The 4th U.S. Artillery, Battery E was an artillery battery that served in the Union Army during the American Civil War. The unit fought at the battles of Kernstown, Port Republic, Rappahannock Station, Second Bull Run, Chantilly, Antietam, and Fredericksburg in 1862. The battery transferred to the Cavalry Corps where it served for the rest of the war. In 1863, 4th U.S. Artillery, Battery E fought at Chancellorsville, Gettysburg, Culpeper, Bristoe Station, and Mine Run. In 1864, the unit fought at the Wilderness, Todd's Tavern, Yellow Tavern, Totopotomoy, Cold Harbor, the Wilson-Kautz Raid, Opequon, Fisher's Hill, and Cedar Creek. In 1865, it saw action at Dinwiddie Court House, Five Forks, Sailor's Creek, and Appomattox before taking part in the Grand Review of the Armies.