Urías pitched two innings of relief in game five of the 2016 National League Division Series, picking up the win. At 20 years, 62 days old he became the youngest Dodgers pitcher to ever pitch in the postseason. He was two weeks younger than Don Drysdale was in game four of the 1956 World Series. He was also the fourth-youngest pitcher in MLB postseason history, behind Ken Brett (1967 World Series), Bert Blyleven (1970 ALCS), and Don Gullett (1970 NLCS and 1970 World Series). He became the youngest pitcher ever to start a postseason game when he started game four of the 2016 National League Championship Series. He allowed four runs in only innings in the game.