Lozano moved to the United States in 1980 to play for the Washington Diplomats, but soon returned to Belgium, being acquired by R.S.C. Anderlecht where he continued to regularly put on stellar performances. In 1982–83, he was instrumental in the Brussels side's UEFA Cup conquest – a 2–1 aggregate win against S.L. Benfica – scoring in the second leg in Lisbon with his head.