From 20 September 1508 to March 1514, he was governor of Capranica, Lazio. During the War of the League of Cambrai, he was named legate to the papal army on 11 December 1510. He participated in the planning of the conquest of Concordia sulla Secchia on 17 December 1510 and the victory at the Siege of Mirandola on 20 January 1511.