Wieruszów was granted town rights, when it was part of Piast-ruled Poland. The town developed in the Late Middle Ages under the patronage of the Polish noble Wierusz family. It was a private town, administratively located in the Sieradz Voivodeship in the Greater Poland Province of the Polish Crown. The local Catholic parish was erected in 1386 by Przecław of Pogorzela, Bishop of Wrocław. In 1401, Bernard Wierusz founded the Pauline monastery. Augustyn Kordecki, prior of the Jasna Góra Monastery in Częstochowa, commander of the heroic and successful Polish defense of Jasna Góra during the Swedish invasion in 1655, died in the monastery in Wieruszów in 1673. The monastery was rebuilt in its present form in 1676 in Baroque style. The church interior contains nine Baroque altars and choir stalls from 1682. There is a portrait of Bernard Wierusz, the first owner and founder of the church at the choir.