In , Speed became the first American driver to race in Formula One since Michael Andretti in , when he made his début at the 2006 Bahrain Grand Prix for Scuderia Toro Rosso. He contested 28 races, before he was replaced midway through the season by Sebastian Vettel. Speed later turned his career towards stock car racing, specifically NASCAR where he drove for Team Red Bull, Whitney Motorsports and Leavine Family Racing in the Sprint Cup Series. Subsequently, he moved into Global Rallycross with Andretti Autosport, winning the title in 2015, 2016 and 2017. He won the 2018 Americas Rallycross Championship with Andretti before racing in 2019 with Subaru Rally Team USA.