Starting for the American national team in 2001, she won a silver medal in the 60 metres competition at the 2001 IAAF World Indoor Championships. She later repeated the event at the 2003 Indoor Championships, but was upgraded to gold winner after Zhanna Block was disqualified for doping. At the 2003 World Championships in Athletics she won silver in the 4 x 100 m relay, along with teammates Chryste Gaines, Inger Miller, and Torri Edwards. Williams also competed in the 4 x 100 metres relay at the 2004 Summer Olympics, with the American team easily winning in the first heat but not being able to finish in the final. In 2002, Angela Williams became the first person to win four consecutive individual NCAA titles in the 100m. In 1999, she won in 11.04 at the age of 19. In 2000, she clocked 11.12, 11.05w in 2001 and 11.29 in 2002.