She returned to Norfolk for repairs on 1 January 1847, then arrived at Veracruz on 21 March 1847, carrying Perry to take command of the American fleet. At once she and her men plunged into amphibious operations against Veracruz, supplying guns and their crews to be taken ashore for the battery which fought the city to surrender in four days. Through the remainder of the war, "Mississippi" contributed guns, men, and boats to a series of coastal raids on Mexico’s east coast, taking part in the capture of Tabasco in June 1847.