Major Zane participated in the fighting in the vicinity of Belleau Wood, when the untried Marines came up against the 461st Imperial German Infantry, a unit that Colonel Robert D. Heinl called "the largest single body of combat-seasoned regular troops which Marines had confronted since Bladensburg" (1814). Zane took part in the second phase of the assault, when the 2nd Battalion 6th Marines and 3rd Battalion 6th Marines entered the wood, and remained in action through the entire period of fighting.