As well as appearing in the BBC children's programmes "Dark Season" (alongside Kate Winslet) and "Moondial", Pearce appeared in the "Doctor Who" serial "The Two Doctors" as Chessene, a bloodthirsty alien, taking the role at short notice after Elizabeth Spriggs had left the production. She was later associated with "Doctor Who" again through her appearances in "The Fearmonger" as Sherilyn Harper, an audio drama by Big Finish Productions, and as Admiral Mettna in the webcast story "Death Comes to Time". Pearce returned to "Doctor Who" from 2015, this time opposite John Hurt, as a regular in the Big Finish audio series based on the adventures of the War Doctor, portraying Cardinal Ollistra, a leader of the Time Lords in the Time War who often clashes with the Eighth Doctor and the War Doctor over how far the Time Lords should be willing to go to achieve victory.