Gheorghe Grigore Cantacuzino (22 September 1833 – 22 March 1913), was a Romanian politician and lawyer, one of the leading Conservative Party policymakers. Among his political posts were minister of public instruction in Romania, president of the chamber, and president of the senate. He twice served as the Prime Minister of Romania: between 23 April 1899 and 19 July 1900, and between 4 January 1906 and 24 March 1907. He resigned from office after failing to put down the large-scale peasants' revolt. He was the 20th Romanian politician to serve as PM.