In the 2009–10 season, Shakhtar regained the Premier League title. On 28 August, he played in Shakhtar's 1–0 extra time loss to Barcelona in the 2009 UEFA Super Cup, picking up a yellow card on 65 minutes. He scored the third goal in a 4–1 away victory over Club Brugge in the Europa League. He scored a goal and picked up a yellow card in a 2–0 Ukrainian Cup victory over Dynamo Kyiv on 28 October. He netted his first league goal of the season in a 2–1 victory against Zorya Luhansk on 20 March. On 3 April, he scored the only goal in a league victory over Obolon. Srna played 39 matches, 26 in the league, and scored four goals, two of which came in the league.