By 1950 "Le Petoulet" was successful enough to be offered a works drive for the Gordini team, in the newly formed Formula One World Championship racing series. He competed in Formula One every year until his retirement after the 1964 season. During this long career Trintignant scored two victories, both at the Monaco Grand Prix, in 1955 and 1958. 1954 and 1955 were his best Championship years and he finished fourth in the Drivers' Championship in both.