In the heats of the 100 metres, Kwakye finished in second place behind Torri Edwards, clocking a time of 11.30 seconds, allowing her to progress through to the quarter-final stage. In the quarter-final, she was beaten to the line by Shelly-Ann Fraser and Evgeniya Polyakova, but still qualified for the semi-final by finishing in third place. In the semi-final on 17 August 2008, Kwakye finished third, with a time of 11.19. She became the first British woman to reach the 100 metres final since Heather Oakes in 1984. At these Olympics, Kwakye was also the only European athlete to appear in the final. In the final, she clocked 11.14, a personal best, to finish in sixth place, ahead of Debbie Ferguson-McKenzie of the Bahamas and Torri Edwards of the US.