Mary D'Souza Sequeira (born 18 July 1931) is an Indian female Olympian who competed internationally in track and field and field hockey. She competed in the women's 100 and 200 metres at the 1952 Summer Olympics. D'Souza won a bronze medal in the 200 metres and a silver medal in the relay at the 1951 Asian Games with Pat Mendonca (her cousin), Banoo Gulzar and Roshan Mistry.