After the fall of Edessa in 1144, Antioch was attacked by Nur ad-Din during the Second Crusade. Much of the eastern part of the Principality was lost, and Raymond was killed at the battle of Inab in 1149. Baldwin III of Jerusalem was technically regent for Raymond's widow Constance until 1153 when she married Raynald of Châtillon. Raynald, too, immediately found himself in conflict with the Byzantines, this time in Cyprus; he made peace with Manuel I Comnenus in 1158, and the next year Manuel arrived to take personal control of the Principality. From thence the Principality of Antioch was to be a vassal of Byzantium until Manuel's death in 1180. Although this arrangement meant that the Principality had to provide a contingent for the Byzantine Army (troops from Antioch participated in an attack on the Seljuk Turks in 1176), it also safeguarded the City against Nur ad-Din at a time when it was in serious danger of being overrun.