Cora was a member of the Red Sox team that won the 2007 World Series. During the regular season, he appeared in 83 games and batted .246 with three home runs and 18 RBI. In the postseason, he appeared as a late-innings defensive replacement in two games of the 2007 ALCS and two games of the World Series. He had one plate appearance, a sacrifice bunt in World Series game 3.