Early in 1864 came the Battle of Morton's Ford, on February 6 and 7, and three months later the Overland Campaign began. The 5th Michigan saw action in several battles of this campaign, including the Battle of the Wilderness on May 6 and 7, the Battle of Totopotomoy Creek from May 28 to 31, and the Battle of Cold Harbor from May 31 to June 1. After the First Battle of Deep Bottom on July 27 and 28, the unit was ordered back towards Washington, D.C., to take part in Sheridan's Shenandoah Valley Campaign from August to October. The 5th Michigan saw action in the Battles of Trevilian Station, Opequon, Fisher's Hill, and Cedar Creek. The next spring, in late March and early April 1865, the regiment took part in a series of battles of the Appomattox Campaign: at Dinwiddie Court House, Five Forks, Sayler's Creek, Appomattox Station, and finally Appomattox Court House, which ended with the surrender of the Confederate Army. After participating in one last expedition, the regiment headed to Washington in May, where it took part in the Grand Review of the Armies.