The series brings together four or five participants, sometimes from opposing sides. The first episode reunited the team behind the world's first IVF baby, Louise Brown. Other examples include Robben Island prisoners in Cape Town, representatives from Labour and BBC to discuss the Hutton Inquiry, perpetrators and victims of the Brighton hotel bombing, and Maids of Honour from the 1953 Coronation. The panel discussion is interspersed with archive audio and narration of the event by the presenter.