"Boquita" Sensini debuted for his national team in 1987, and played his last match in 2000. He played in the World Cup 1990, 1994 and 1998. In the 1990 FIFA World Cup Final Sensini conceded the disputed penalty kick from which West Germany scored their winning goal. He helped his country to a third-place finish at the 1989 Copa América, and he was also part of the championship teams in the 1991 Copa América and 1993 Copa América tournaments, as well as the silver medal-winning team at the 1996 Summer Olympics in Atlanta, as one of the three over-23 players allowed per squad.