In 1982 Patrese moved to Brabham and gained his maiden win at that year's Monaco Grand Prix in rather sensational circumstances. Patrese took the lead when Alain Prost crashed out, only to spin in dampening conditions on the next lap. This left him third behind Didier Pironi and Andrea de Cesaris, who both stopped on the final lap – Pironi with an electrical fault and de Cesaris out of fuel. Later that season he also led the Austrian Grand Prix but retired due to an engine failure. Patrese finished the season tenth, just ahead of his teammate Nelson Piquet. 1983 proved to be a more difficult season. Patrese crashed out late in the race while leading at San Marino - to the cheers of the "tifosi", as his shunt meant that he handed the race win to Ferrari driver Patrick Tambay. He also took pole on home ground at the Italian Grand Prix, before his engine blew up in the early stages of the race: in a 2010 interview he said he suspected that his engine had been left in its qualifying trim, rendering it extremely powerful but fragile, as he had not been offered a new contract for the following year, and had been reluctant to sacrifice his chances of winning his home Grand Prix for teammate Nelson Piquet, who was fighting for the World Championship. Despite scoring a second win at the South African Grand Prix, Patrese only finished ninth while Piquet claimed his second Drivers' Championship title. It would be seven years before he made another visit to the top step of the podium.