So was awarded the Samford Fellowship in March 2016, enabling him to secure Vladimir Tukmakov as his coach. In August 2016, So finished clear first at the 2016 Sinquefield Cup, ahead of former World Champions Viswanathan Anand and Veselin Topalov, 2014 winner Fabiano Caruana, and 2015 winner Levon Aronian. He won 2 games and drew 7 games. In December 2016, So also finished clear first at the 2016 London Chess Classic, ahead of former World Champions Viswanathan Anand, Vladimir Kramnik and Veselin Topalov. He won 3 games and drew 6 games (+3−0=6). In winning the Sinquefield Cup, the London Chess Classic, and finishing second at the Your Next Move Leuven rapid and blitz tournament, he won the 2016 Grand Chess Tour. So's first appearance for the United States yielded individual gold medal for board 3 as well as team gold at the Chess Olympiad held in Baku.