Between 1837 and 1847 the 27th Regiment was engaged in several of the Xhosa Wars in South Africa. In 1840, the spelling 'Enniskillen' was changed to 'Inniskilling'. The Gaelic form of the name is "Inis Ceithleann" ('the Island of Kathleen'), which is captured by various anglicisations. The Regiment was also nicknamed "The Skins". From 1854 and 1868 it served in India as part of the suppression of the Indian Mutiny and helped to maintain law and order in North-West India.