Wendlinger's Formula One debut came at the 1991 Japanese Grand Prix at Suzuka, bringing some money to the beleaguered Leyton House team in place of long-serving Ivan Capelli. He qualified in 22nd place in a field of 26, but was unable to convert that into anything more, after he retired due to a big collision at turn one, between himself, JJ Lehto, Andrea de Cesaris and Emanuele Pirro. His second race didn't fare much better as the Adelaide circuit was a wash-out, torrential rain leading to a curtailed event. Wendlinger was classified in 20th place, two laps down on eventual winner Ayrton Senna, after aquaplaning on some of the huge puddles of water present that day.