On 29 June 2011, Pulzetti was signed by Bologna for €3.3 million, with half of the fee paid via Riccardo Regno. He signed a four-year contract worth about €320,000 net annually, plus bonuses. He played a full season with Bologna in 2011–12, but appeared only occasionally the following season. He spent the 2013–14 season on loan at Serie B club Siena, and returned to his first club, Cesena, for 2014–15, also on loan.