At the 2006 Italian Grand Prix, Yamamoto had a major effect on the championship after suffering a tyre delamination during qualifying, which consigned him to last place on the grid. Later on in the session, Fernando Alonso punctured a tyre on debris from this incident, an occurrence which would eventually result in the points leader being penalised for blocking Felipe Massa and dropping from fifth to tenth on the grid. During the race, Yamamoto suffered hydraulic problems and had to start from the pit lane, eventually retiring when it became terminal.