Frederick R. Weedon (1784–1857) was a contract surgeon to the U.S. Army during the Second Seminole War and was the physician who attended to the ailing Seminole warriors Osceola and Uchee Billy after their capture, and was notorious for decapitating their heads after they died. Weedon was born in Maryland, moved to Alabama and then the Florida Territory where he was the first to receive a permit for land under the Armed Occupation Act of 1842 in Mosquito County (today that area is St. Lucie County).