In 2004, Hoàng Xuân Thanh Khiết won silver medal in Vietnamese Women's Chess Championship, but in 2005, she won Vietnamese Women's Chess Championship. In 2005, Hoàng Xuân Thanh Khiết won 3rd place in Women's World Chess Championship Asian Zonal tournament un got the right to participate in the Women's World Chess Championship. In 2006, Hoàng Xuân Thanh Khiết participated in Women's World Chess Championship by knock-out system and in the first round lost to Xu Yuhua.