The 43rd were sent to South Africa for service in the Eighth Xhosa War in 1851. In 1852 a detachment from the regiment departed Simon's Town aboard the troopship HMS "Birkenhead" bound for Port Elizabeth. At two o'clock in the morning on 28 February 1852, the ship struck rocks at Danger Point, just off Gansbaai. The troops assembled on deck, and allowed the women and children to board the lifeboats first, but then stood firm as the ship sank when told by officers that jumping overboard and swimming to the lifeboats would mostly likely upset those boats and endanger the civilian passengers. 357 men drowned. The bravery and discipline shown by British troops which included a detachment of the 43rd under the command of Lieutenant Girardot during the ship-wreck received much publicity in England and abroad. King Frederick of Prussia ordered that the story of the bravery shown during the sinking of the troopship be read out to each regiment of his army as an example of devotion to duty.