Starting in the centre of Gori the S10 runs north from the Gori Fortress out of town towards the S1 highway. This highway provides a motorway connection to Tbilisi and the western parts of Georgia. Passing underneath the motorway the S10 runs in a straight line through the flat agricultural land towards Karaleti village parallel to the Liakhvi river at a distance of a few kilometers. Even through the road is closed for through traffic into Tskhinvali and South Ossetia, it has importance in the area just south from it with many Georgian communities near the boundary line. The highway connects them with the rest of Georgia. Just north from Ergneti village a roadblock at the boundary line prevents further travel. Since the 2008 war the site is used for conflict resolution meetings and exchange of detainees involving international actors.