Tarcondimotus at first supported Pompey in the civil war against Julius Caesar, but after Pompey's defeat and death, he was pardoned by Caesar and confirmed in his title and possessions. The name of Tarcondimotus' daughter is probably an indication that he received the Roman citizenship from Caesar as well. During the Liberators' civil war, he sided with Gaius Cassius Longinus, and after that with Mark Antony, whom he followed in the opening stages of the war against Octavian.