Clark was harpist with the Denver Philharmonic Society as a young woman. In 1915 she performed at the Panama-Pacific International Exposition in San Francisco, demonstrating harps for the Rudolph Wurlitzer Company. In 1917 and 1918 she toured North America with Swiss cellist Elsa Ruegger. During the 1919-1920 season, she was harpist with the Seattle Symphony Orchestra. She transcribed and arranged Charles Wakefield Cadman's "From the Land of the Sky Blue Water" for solo harp. By 1928 she was billed as "America's foremost harpist." In 1931, she served on the faculty of the Mount St. Mary's College summer school, teaching harp.