In January 2011, Talavera received his first call-up to the Mexico national team by José Manuel de la Torre for a friendly match against Bosnia and Herzegovina. He made his international team debut on 26 March 2011 in a friendly against Paraguay which "El Tri" won 3–1. He was called for the team's 2011 CONCACAF Gold Cup squad as a third choice goalkeeper after José de Jesús Corona and Guillermo Ochoa. Following Corona's "Liguilla" scandal with Cruz Azul and Ochoa's clenbuterol issue, Talavera became Mexico's first-choice goalkeeper, despite having only one international cap. Overall, he saw action in five matches of that tournament and was a starter in the final against United States, where Mexico would go on to win 4–2.