Deriglazova climbed her first World Cup podium in 2011 with a silver medal in Tauberbischofsheim. She was stopped by Korea's Nam Hyun-hee in the table of 16 of the 2011 World Championships in Catania. In the team event, Russia defeated France in the quarter-finals, then Korea to meet the Italian "Dream Team". Russia lost by a single hit and were doomed to a silver medal. At the 2012 European Championships she defeated reigning Olympic silver medallist Arianna Errigo in the semi-finals and prevailed over teammate Kamilla Gafurzianova to earn her first senior individual title. For her Olympic début at London 2012, she was defeated 8–15 in the second round of the individual event by France's Ysaora Thibus. In the team event Russia got the best of Japan, then of South Korea. They met No.1 rivals Italy in the final. Deriglazova opened the match against five-time Olympic champion Valentina Vezzali and was defeated 2–5. Her teammates could not contain Italy either and Russia were eventually defeated 31–45.