Zambia competed at the 2000 Summer Paralympics in Sydney, Australia. It was the country's second participation in the Paralympic Games. Wheelchair athlete Lango Sinkamba, who had competed in the 1996 Games, took part for the second time, entering the marathon. Visually impaired sprinter Nancy Kalaba, Zambia's only other representative, made her Paralympic début, in the 100m race. Neither of them won a medal.