On 19 July Doornbos was appointed as a Minardi race driver for the 2005 German Grand Prix onwards, replacing Austrian Patrick Friesacher, who had encountered sponsorship issues. In his first Formula One race, he collided with Jacques Villeneuve, the man who gave advice to Doornbos to start his career as a race driver. Doornbos raced a total of eight Grand Prix for the team, his best result being a 13th position in the Turkish and Belgian Grands Prix.