He qualified for his second PDC World Championship in 2012, where he beat Dennis Nilsson 4-2 in legs in the preliminary round to set up a last 64 meeting with 15-time world champion, Phil Taylor. He was beaten 0-3 but did manage to win three legs during the match, including breaking Taylor's throw twice. Taylor said after the match that Muramatsu would have "frightened any pro" with the level of his performance during the match. He moved to 94 in the PDC Order of Merit after the Championship. Muramatsu represented Japan with Morihiro Hashimoto in the 2012 PDC World Cup of Darts and together they were beaten 2-5 by Sweden in the first round.