MSF's first mission was to the Nicaraguan capital, Managua, where a 1972 earthquake had destroyed most of the city and killed between 10,000 and 30,000 people. The organization, today known for its quick response in an emergency, arrived three days after the Red Cross had set up a relief mission. On 18 and 19 September 1974, Hurricane Fifi caused major flooding in Honduras and killed thousands of people (estimates vary), and MSF set up its first long-term medical relief mission.