Rapuano officiated in the World Series in 2001 and 2003, as well as the All-Star game in 1995 and 2008. He also worked in five League Championship Series (1999, 2000, 2002, 2004, 2005) and seven Division Series (1997, 1998, 2001, 2003, 2006, 2008, 2010), and the NL's one-game wild card playoff in 1999. He was also an umpire in the 2009 World Baseball Classic. Rapuano wore number 19 from 2000 to his retirement in 2012 (Rapuano wore number 23 during his NL tenure, but AL umpire Rick Reed had more seniority and claimed the number).