In early January 2011 Wyludda revealed in Bild that she had to have her right leg amputated because of Sepsis. After losing her leg she returned to athletics and began entering para-sport competitions. In 2012, she represented Germany at the London Paralympics becoming the first German athlete to have represented her country at both Olympic and Paralympic Games. In 2014, she entered the IPC European Championships in Swansea, taking the bronze medal in the F57 discus and silver in the shot put.