With Toronto, Cone was 4–3 with a 2.55 ERA and 47 strikeouts. Combined with the 214 strikeouts he had with the Mets, his 261 strikeouts led the major leagues and were career-highs. Cone headed to the post-season for the second time in his career as the Blue Jays won the American League East. The Jays defeated the Oakland Athletics in the 1992 American League Championship Series, and the Atlanta Braves in the World Series, to give Cone his first World Series ring, and become the first Canadian team to win the World Series. For his part, Cone went 1–1 with a 3.22 ERA in the post-season.