After two years at Oregon, Wise turned professional after the NCAA championship. He made his professional debut after qualifying for the U.S. Open, also his first major championship appearance. He missed the cut after shooting rounds of 74-76. In his third start as a professional, he won the Syncrude Oil Country Championship on the PGA Tour Canada. He finished fourth on the Order of Merit and earned a Web.com Tour card for the 2017 season.