The previous opinion of health workers who are against the administration of the cholera vaccine voiced that resources should be directed at rehydration and the provision of safe water and improved sanitation. This is because sanitised environments, appropriately cooking food before consumption, using sterilised water and following general personal hygiene, decrease the spread of cholera. As of yet, cholera control activities have been focused on emergency responses to outbreaks, with limited attention to the underlying causes that can prevent future recurrence. However, the development of new and improved cholera vaccines has allowed this approach to be revised. Further, recent research has advanced our understanding of cholera, its transmission and the immune response. Subsequently, a result of these advances has been the development of experimental cholera vaccines derived from non-living and attenuated live strains. The FDA recently approved a single dose live oral cholera vaccine called Vaxchora for adults aged 18–64 who are travelling to an area of active cholera transmission. Furthermore, a Haiti study shows lasting protection from a two-dose cholera vaccine. During the 2010–2017 cholera outbreak in Haiti, those who received the two doses of the vaccine were 76% less likely to become sick. This protection lasted 4 years.