Trippier started his career in the youth system at Manchester City but failed to make the breakthrough to the first team, having two loans at Championship club Barnsley. In 2011, he signed for Championship club Burnley on a season-long loan which was made permanent in January 2012 for an undisclosed fee. He was named in the Championship PFA Team of the Year for two consecutive seasons in 2012–13 and 2013–14. In 2014, he secured promotion with Burnley to the Premier League as the team finished runners-up in the Championship. A year later, he signed for Tottenham Hotspur for a £3.5 million fee. After four years in North London, during which he became part of the squad that finished as runners up in the 2019 Champions League final, Trippier joined Spanish side Atletico Madrid, where he helped the team win the 2020–21 La Liga title.