My husband was diagnosed last month with cholangiocarcinoma and is currently going through chemotherapy. He is on extended release morphine sulphate for pain. Initially, he was taking Miralax to fend off constipation, but his doctor changed him to Senna and, unfortunately, is now experiencing constipation . . . the Senna is not working effectively for him and he has not voided his bowels in 3 days. This AM he took Miralax again, but has had no relief. He has taken several short walks, hoping the exercise would help, but nothing so far. What other recommendations might you have for the constipation? Another dose of Miralax?

Summarized question: What causes constipation when with cholangiocarcinoma?