SUBJECT: Janumet XR 50mg/1000mg- 1 daily
MESSAGE: Doctor prescribed for type 2 diabetes w/Metformin 500 mg 2 times daily. Pharmacy refused to fill stating overdose of Metformin. Who is right &what is maximum daily dosage of Metformin? Pharmacy is a non-public pharmacy for a major city employer plan provided for employees only.

Summarized question: What is the maximum dosage of metformin?