Coming off a primetime victory over Cincinnati, the Colts flew to Reliant Stadium for an AFC South rematch with the Houston Texans. Heading into this game, Indianapolis had never lost a game to the Texans, winning their first 9 games against them. In the first quarter, the Colts got an early shock as RB Ron Dayne ran for a 3-yard touchdown and a 6-yard touchdown run.  Indianapolis would respond with 37-yard touchdown pass from QB Peyton Manning to WR Marvin Harrison. In the second quarter, the Colts tied the game with Manning completing a 9-yard touchdown pass to WR Aaron Moorehead. However, Houston reclaimed its lead with QB David Carr's 3-yard touchdown pass to RB Vonta Leach. In the third quarter, Indianapolis crept closer with K Adam Vinatieri making a 33-yard field goal for the only score of the period. In the fourth quarter, the Texans responded with kicker Kris Brown's 42-yard field goal. Afterwards, the Colts tied the game with Manning hooking up with Harrison again on a 7-yard touchdown pass, Harrison's second of the game. However, Houston managed to pull off a huge upset with Kris Brown's game-winning 48-yard field goal as time expired, giving Indianapolis their first ever loss against them. With the loss, the Colts fell to 11-4. Colts QB Peyton Manning finished the game 21 of 27 for 205 yards passing with three touchdowns and Texans QB David Carr finished with 163 passing yards on completing 16 of 23 passes with one touchdown. Rookie RB Joseph Addai ran the ball 15 times for 100 yards and former Heisman Trophy winner Ron Dayne finished the game with 153 rushing yards on 32 carries. After this game, the Colts were now 11-4, having lost 4 of 6 after a 9-0 start and dropped to 4-4 on the road.

Question: Which team was in the lead in the second quarter?
Answer: Houston reclaimed its lead

Question: How many passes did Harrison catch?
Answer: 2

Question: Who threw the longest touchdown pass?
Answer: Peyton Manning

Question: Who caught the shortest touchdown pass?
Answer: Harrison

Question: How many passing touchdowns of 10-yards or less were scored?
Answer: 3

Question: How many more passing touchdowns did Peyton Manning have compared to David Carr?
Answer: 2

Question: How many field goals over 40-yards were kicked?
Answer: 2

Question: How many yards did Ron Dayne gain on his first two touchdowns?
Answer: 9

Question: How many more yards did Peyton Manning gain on his first touchdown when compared to Ron Dayne's first two touchdowns?
Answer: 28

Question: Which quarterback threw for the shortest touchdown?
Answer: David Carr

Question: How many total completions were gained when both quarterback's stats are observed?
Answer: 37

Question: How many total incompletions were gained when both quarterback's stats are observed?
Answer: 13

Question: Which quarterback threw for more incomplete passes during the game?
Answer: David Carr

Question: How many yards per passing play did Peyton Manning average during this game?
Answer: 9.76

Question: How many yards per passing play did David Carr average during this game?
Answer: 10.18

Question: How many more passing yards did Peyton Manning have when compared to Joseph Addai's rushing yards?
Answer: 105

Question: How many yards per rush did Joseph Addai average throughout the game?
Answer: 6.66

Question: How many field goals did Brown kick in the fourth quarter?
Answer: 2

Question: How many field goals did Brown kick in the second half?
Answer: 2

Question: How many field goals did Vinatieri kick in the third quarter?
Answer: 1

Question: How many field goals did Vinatieri kick in the second half?
Answer: 1