passages.id: 27457
passages.type: title
passages.text: Acute renal failure in high dose carboplatin chemotherapy.
passages.id: 27458
passages.type: abstract
passages.text: Carboplatin has been reported to cause acute renal failure when administered in high doses to adult patients. We report a 4 1/2-year-old girl who was treated with high-dose carboplatin for metastatic parameningeal embryonal rhabdomyosarcoma. Acute renal failure developed followed by a slow partial recovery of renal function. Possible contributing factors are discussed.