passages.id: 12735
passages.type: title
passages.text: Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis.
passages.id: 12736
passages.type: abstract
passages.text: Skin rashes, proteinuria, systemic lupus erythematosus, polymyositis and myasthenia gravis have all been recorded as complications of penicillamine therapy in patients with rheumatoid arthritis. A patient who had developed all 5 is now described. The skin lesion resembled elastosis perforans serpiginosa, which has been reported as a rare side effect in patients with Wilson's disease but not in patients with rheumatoid arthritis treated with penicillamine.