标题：达朝山
学习经历
2010年3月—2011年3月，美国宾夕法尼亚大学化学系, 访问学者，合作者Patrick J. Walsh教授。
2000年9月—2003年6月，兰州大学生命科学学院生物化学与分子生物学研究所，从事博士学位的学习和研究工作，获得理学博士学位，导师王锐教授。 
1998年9月—2000年6月，兰州大学生命科学学院生物化学与分子生物学研究所，从事硕士学位的学习和研究工作，获得理学硕士学位，导师王锐教授。 
1986年9月—1990年6月，兰州大学原生物系植物生理专业学习，获得理学学士学位。
工作经历
2010-至今，兰州大学，生命科学学院生物化学与分子生物学研究所，教授，博士生导师。 
2007-2010，兰州大学，生命科学学院生物化学与分子生物学研究所，副教授，硕士生导师。 
2005-2007，兰州大学，生命科学学院生物化学与分子生物学研究所，讲师，硕士生导师。 
2003-2005，兰州大学，生命科学学院生物化学与分子生物学研究所，讲师。 
1990-1997，甘肃省科学院，生物研究所，研究实习员。 　
研究方向
主要从事手性药物与多肽合成法放学研究。我们研究组现在的兴趣主要集中于：（1）手性药物的绿色与原子经济性相关的不对称催化合成方法学研究；（2）不对称格式反应合成手性药物及其中间体；（3）高级结构相关酶模拟物的合成与催化活性研究。
项目成果
国家自然科学基金项目：
格氏试剂的钝化及其在手性配体作用下对醛的不对称加成反应研究，国家自然科学基金，No. 20672051，28万元，2007年至2009年。 
脱水酶的高级结构肽模拟物的设计、合成及其催化β-羰基醇脱水反应过程中的手性识别作用研究，国家自然科学基金，No. 21072087, 36万元，2011年至2013年。　
所获奖励
2008年甘肃省自然科学奖一等奖。完成人：王锐，许兆青，达朝山，杨晓武，张邦志。项目名称：具有重要医药用途的若干不对称催化合成方法学研究 。（2008-Z1-002-R3）。 
2009第十六届“甘肃省普通高等学校青年教师成才奖”。　
发表文章
Da, Chao-Shan; Xin, Zhuo-Qun; Xiao, Yi-Nan; Wang, Heng-Shan; Su, Wu; Yang, Fan; Wang, Rui. 新的含大体积取代基的β-氨基醇配体的合成及在二乙基锌对芳香醛的不对称加成反应中的应用, 有机化学 2004, 24, 943-945.
刘大学，汪权，张立臣，达朝山，王锐, 手性联萘酚锂盐催化下三甲基硅氰与芳香醛的对映选择加成反应研究, 高等学校化学学报 2001，22，601-602. (CAJ)
粟武，王恒山，达朝山，王锐, 光活性1,1'-联萘酚(BINOL)的不对称合成, 高等学校化学学报 2000，21，1408-1409. (CAJ)
王恒山，杨晓武，粟武，刘大学，达朝山，王锐, 树脂固定化手性联萘酚2钛催化剂的合成及其催化特性研究, 高等学校化学学报 2000，21，1524-1525. (CAJ)
一、发表SCI论文情况
Zhang, J.; Stanciu, C.; Wang, B.; Hussain, M. M.; Da, C. S.; Carroll, P. J.; Dreher, S. D.; Walsh, P. J. Palladium-Catalyzed Allylic Substitution with (η-Arene-CH2Z)Cr(CO)3- Based Nucleophiles. J. Am. Chem. Soc.2011, 133, 20552-20560.
Qin, L.; Li, L.; Yi, L.; Da, C. S.; Zhou, Y. F. Direct Asymmetric N-Specific Reaction of Nitrosobenzene with Aldehydes Catalyzed by a Chiral Primary Amine-Based Organocatalyst, Chirality2011, 23, 527-533.
Fan, X. Y.; Yang, Y. X.; Zhuo, F. F.; Yu, S. L.; Li, X.; Guo, Q. P.; Du, Z. X.; Da, C. S. AlCl3 and BDMAEE: A Pair of Potent Reactive Regulators of Aryl Grignard Reagents and Highly Catalytic Asymmetric Arylation of Aldehydes Chem. Eur. J.2010, 16, 7988-7991. 
This work was highlighted by Synfacts (Yamamoto, H.; Brady, P. Synfacts2010, 10, 1164). 
Liu, Y.; Da, C. S.; Yu, S. L.; Yin, X. G.; Wang, J. R.; Fan, X. Y.; Li, W. P.; Wang, R. Catalytic Highly Enantioselective Alkylation of Aldehydes with Deactivated Grignard Reagents and Synthesis of Bioactive Intermediate Secondary Arylpropanols J. Org. Chem.2010, 75, 6869 -6878.
Zhu, G. J.; Da, C. S.; Jia, Y. N.; Ma, X.; Yi, L. Direct Asymmetric Aldol Reaction Catalyzed by C2-symmetrical Chiral Primary Amine Organocatalysts, Lett. Org. Chem.2010, 7, 15-20. 
Da, C. S.; Wang, J. R.; Yin, X. G.; Fan, X. Y.; Liu, Y.; Yu, S. L., Highly Catalytic Asymmetric Addition of Deactivated Alkyl Grignard Reagents to Aldehydes, Org. Lett.2009, 11, 5578-5581. This work was highlighted by Synfacts(Lautens, M.; Candito, D. A. Synfacts2010, 3, 323.) andOrganic Chemistry: Highlights (Taber, D. F. Org. Chem. Highlights 2010, July 12.) 
Wu, F. C.; Da, C. S.; Du, Z. X.; Guo, Q. P.; Li, W. P.; Yi, L.; Jia, Y. N.; Ma, X. N-Primary-Amine-Terminal β-Turn Tetrapeptides as Organocatalysts for Highly Enantioselective Aldol Reaction, J. Org. Chem.2009, 74, 4812-4818.
Da, C. S.; Che, L. P.; Guo, Q. P.; Wu, F. C.; Ma, X.; Jia, Y. N. 2,4-Dinitrophenol as An Effective Cocatalyst: Greatly Improving the Activities and Enantioselectivities of Primary Amine Organocatalysts for Asymmetric Aldol Reactions, J. Org. Chem.2009, 74, 2541-2546. 
Ma, X.; Da, C. S.; Yi, L.; Jia, Y. N.; Guo, Q. P.; Che, L. P.; Wu, F. C.; Wang, J. R.; Li, W. P. Highly efficient primary amine organocatalysts for the direct asymmetric aldol reaction in brine, Tetrahedron: Asymmetry2009, 20, 1419-1424.
Jia, Y. N.; Wu, F. C.; Ma, X.; Zhu, G. J.; Da, C. S. Highly efficient prolinamide-based organocatalysts for the direct asymmetric aldol reaction in brine, Tetrahedron Lett.2009, 50, 3059-3062.
Yang, R. Y.; Da, C. S.; Yi, L.; Wu, F. C.; Li, H. Asymmetric conjugate addition of unmodified propionaldehyde to β-nitrostyrenes catalyzed by readily available proline-based dipeptidols, Lett. Org. Chem.2009, 6, 44-49. 
Li, H.; Da, C.-S.; Xiao, Y. H.; Li, X.; Su, Y. N. Direct Asymmetric Aldol Reaction of Aryl Ketones with Aryl Aldehydes Catalyzed by Chiral BINOL-Derived Zincate Catalyst, J. Org. Chem.2008, 73, 7398-7401.
Da, C. S.; Ni, M.; Han, Z. J.; Yang, F.; Wang, R. Novel non-azacyclo 1,2-amino alcohols derived from phenylalanine and highly enantioselective addition of diethylzinc to aryl aldehydes, J. Mol. Catal. A: Chem.2006, 245, 1-7.
Han, Z. J.; Da, C. S.; Qiu, L.; Ni, M.; Zhou, Y. F.; Wang, R. The natural amino acid derived chiral sulfonamide ligands in the catalytic asymmetric addition of phenylacetylene to aldehydes, Lett. Org. Chem.2006, 3, 143-148. 
Ni, M.; Wang, R.; Han, Z. J.; Mao, B.; Da, C. S.; Liu, L.; Chen, C. Synthesis of new C2-symmetrical bissulfonamide ligands and application in the enantioselective addition of alkynylzinc to aldehydes and ketones, Adv. Synth. Catal. 2005, 347, 1659-1665.
Kang, Y. F.; Wang, R.; Liu, L.; Da, C. S.; Yan, W. J.; Xu, Z. Q. Enantioselective alkynylation of aromatic aldehydes catalyzed by new chiral oxazolidine ligands, Tetrahedron Lett.2005, 46, 863-865.
Han, Z. J.; Da, C. S.; Xu, Z. Q.; Ni, M.; Wang, R. The asymmetric addition of phenylacetylene to aldehydes catalyzed by L-leucine derived chiral sulfonamide alcohol ligands, J. Mol. Catal. A.: Chem. 2005, 236, 32-38. 
Da, C. S.; Xin, Z. Q.; Xiao, Y. N.; Wang, H. S.; Su, W.; Yang, F.; Wang, R. Novel β-Aminoalcohols with Bulky Substituents and the Application in Enantioselective Addition of Diethyl Zinc to Arylaldehydes(in Chinese), Chin. J. Org. Chem.2004, 24, 943-945.
Zhou, Y. F.; Wang, R.; Xu, Z. Q.; Yan, W. J.; Liu, L.; Gao, Y. F.; Da, C. S. Boc-L-proline as a new chiral ligand for enant ioselective phenylacetylene addition to aromatic aldehydes, Tetrahedron: Asymmetry2004, 15, 589-591.
Xu, Z. Q.; Wang, R.; Xu, J. K.; Da, C. S.; Yan, W. J.; Chen, C. Highly enantioselective addition of phenylacetylene to aldehydes catalyzed by a β-sulfonamide alcohol-titanium complex, Angew. Chem., Int. Ed.2003, 42, 5747-5749.
Wang, H. S.; Da, C. S.; Xin, Z. Q.; Su, W.; Xiao, Y. N.; Liu, D. X.; Wang, R. Enantioselective conjugate addition of diethylzinc to chalcone catalyzed by Ni(acac)2 and chiral β-amino alcohols, Chin. J. Chem.2003, 21, 1105-1107.
Da, C. S.; Han, Z. J.; Ni, M.; Yang, F.; Liu, D. X.; Zhou, Y. F.; Wang, R. A convenient synthesis of piperidine-based β-amino alcohols from L-Phe and highly enantioselective addition of diethyl zinc to aldehydes, Tetrahedron: Asymmetry2003, 14, 659-665. 
Da, C. S.; Wei, J.; Dong, S. L.; Xin, Z. Q.; Liu, D. X.; Xu, Z. Q.; Wang, R. Highly catalytic enantioselective epoxidation of enones with weak base bicarbonate and hydrogen peroxide, Synth.Commun.2003, 33, 2787-2792.
Xin, Z. Q.; Da, C. S.; Dong, S. L.; Liu, D. X.; Wei, J.; Wang, R. A novel method for the synthesis of (R)-2,2'-dihydroxy-1,1'-binaphthyl-3,3'-dicarboxylic acid by asymmetric oxidative coupling of a chiral β-naphthol derivative catalyzed by CuCl, Tetrahedron: Asymmetry2002, 13, 1937-1940.
Liu, D. X.; Zhang, L. C.; Wang, Q.; Da, C.-S.; Xin, Z. Q.; Wang, R.; Choi, M. C. K.; Chan, A. S. C. The application of chiral aminonaphthols in the enantioselective addition of diethylzinc to aryl aldehydes, Org. Lett. 2001, 3, 2733-2735.
Yang, X. W.; Shen, J. H.; Da, C. S.; Wang, H. S.; Su, W.; Liu, D. X.; Wang, R.; Choi, M. C. K.; Chan, A. S. C. Highly enantioselective addition of diethylzinc to aldehydes catalyzed by a new chiral C2-symmetric Ti-diol complex, Tetrahedron Lett. 2001, 42, 6573-6575.
Liu, D. X.; Wang, Q.; Zhang, L. C.; Da, C. S.; Wang, R. Trimethylsilylcyanation of Aromatic Aldehydes Catalyzed by BINOL-Li Salt (in Chinese), Chem. J. Chin. Univ.2001, 22, 601-602.
Yang, X. W.; Su, W.; Liu, D. X.; Wang, H. S.; Shen, J. H.; Da, C. S.; Wang, R.; Chan, A. S. C. Preparation and application of polymer-grafted Ti-BINOL complexes as chiral catalysts in the enantioselective addition of diethylzinc to aldehydes, Tetrahedron2001, 56, 3511-3516.
Yang, X. W.; Sheng, J. H.; Da, C. S.; Wang, H. S.; Su, W.; Wang, R.; Chan, A. S. C. Polymer-Supported BINOL Ligand for the Titanium-Catalyzed Diethylzinc Addition to Aldehydes: A Remarkable Positive Influence of the Support on the Enantioselectivity of the Catalyst, J. Org. Chem.2000, 65, 295-266.
Su, W.; Wang, H. S.; Da, C. S.; Wang, R. Asymmetric Synthesis of Optically Active 1,1'-Bi-2-Naphthol (in Chinese), Chem. J. Chin. Univ.2000, 21, 1408-1409.
Wang, H. S.; Yang, X. W.; Su, W.; Liu, D. X.; Da, C. S.; Wang, R. Preparation of a Polymer Supported BINOL-Ti Catalyst and Its Application in Asymmetric Addition of Diethylzinc to Aldehydes (in Chinese), Chem. J. Chin. Univ.2000, 21, 1524-1525. 
Yang, X. W.; Shen, J. H.; Da, C. S.; Wang, R.; Choi, M. C. K.; Yang, L.; Wong, K. Chiral pyrrolidine derivatives as catalysts in the enantioselective addition of diethylzinc to aldehydes, Tetrahedron: Asymmetry1999, 10, 133-138.
二、专利申请
达朝山，樊新元，卓芳芳，杨永新，不对称催化法合成光学活性二级芳基醇，申请号：CN ，公开号： ， 2010年5月27日。 
达朝山，苏亚宁，洪满贵，保英明，曹福军，一种生长抑素的合成方法，申请号：CN，公开号：，2009年6月3日。 
三、参编书籍
达朝山，王 锐：高效手性配体的设计合成及其在二乙基锌对醛的不对称加成反应中的应用，《不对称有机反应》（第一版），李月明、范青华、陈新滋主编，化学工业出版社，北京，中国，2005年，第6章：pp275-291。
社会工作
现任甘肃省化学会第十六届理事会理事[1]。