标题：李惠静
甘肃省公安厅副巡视员
李惠静 女，汉族，1956年11月出生，山西吉县人，出生地上海市，中央党校大学学历，中共党员。原任省公安厅机关党委专职副书记，2011年7月任省公安厅副巡视员。
哈尔滨工业大学（威海）副教授
基本信息姓　名： 李惠静
职务职称： 博士/副教授/硕士生导师
性　别： 女
专　业： 有机合成/天然产物化学
主要研究方向1. 海洋天然产物分离分析、结构鉴定、合成、结构修饰以及构效关系研究 
2. 与海洋天然产物合成相关的有机合成方法学研究 
3. 高附加值原料药及中间体的研发以及专利药物的合成工艺改进 
4. 催化不对称有机合成新反应和新策略研究 
5. 金属催化的有机新反应研究
学习经历1998 青岛科技大学 分析化学 学士学位 
2004 中国科学院化学研究所 有机化学 博士学位
工作经历2004 美国奥勒冈州立大学 天然产物化学 博士后
2009 法国巴黎大学 金属有机化学 博士后
2011哈尔滨工业大学威海校区海洋科学与技术学院任职 副教授
主要研究成果与获奖情况在中国科学院分子识别与功能重点实验室、美国奥勒冈州立大学环境健康科学中心和法国巴黎大学金属催化实验室从事研究工作多年，在电化学分析、有机合成、天然产物分离分析及结构鉴定、天然产物结构修饰和化学生物学等领域积累了较为丰富的研究经验。发展了三唑类化合物的合成新方法，研究了其生物活性及构效关系。探索了电化学和酶化学在有机合成中的应用。利用Ga3+与手性半冠醚配体的有效结合，成功实现了水介质中高选择性的催化不对称Mukaiyama-Aldol反应。利用有机降解方法和质谱等分析方法鉴定了啤酒花单宁酸的结构，发展组合串联质谱新方法实现复杂、痕量且不稳定的原花色素天然产物的结构鉴定。首次发现了金属Ga3+催化的一种新型串联反应，最多一步反应可同时产生6个环，可以快捷方便的应用于神经抑制剂的合成和复杂多环大分子化合物的合成。
主要学术兼职1.中国化学会会员
2.法国化学会会员
3.美国质谱协会会员
发表论文选列在国内外科技期刊上公开发表学术文章25篇（第一作者19篇），书籍2部（第一作者），应邀口头报告4次（第一作者），会议论文6篇（第一作者4篇）。代表性论文：
[1]Li Hui-Jing, Guillot Regis, Gandon Vincent.* “A Gallium-Catalyzed Cycloisomerization/ Friedel−Crafts Tandem” Journal of Organic Chemistry 2010, 75 (24), 8435–8449. (IF: 4.002)
[2]Li Hui-Jing, Deinzer Max L.* “The mass spectral analysis of isolated hops A-type proanthocyanidins by electrospray ionization tandem mass spectrometry” Journal of Mass Spectrometry 2008, 43(10), 1353–1363. (IF: 3.289)
[3]Li Hui-Jing, Deinzer Max L.* “Tandem mass spectrometry for sequencing proanthocyanidins” Analytical Chemistry 2007, 79, 1739–1748. (IF: 5.874)
[4]Li Hui-Jing, Deinzer Max L.* “Structural identification and distribution of proanthocyanidins in 13 different hops” J. Agric. Food Chem. 2006, 54, 4048–4056. (IF: 2.816)
[5]Li Hui-Jing, Tian Hong-Yu, Wu Yan-Chao, Chen Yong-Jun, Liu Li, Wang Dong,* Li Chao-Jun.* “Aqueous asymmetric Mukaiyama aldol reaction catalyzed by chiral gallium lewis acid with Trost-type semi-crown ligands” Advanced Synthesis & Catalysis 2005, 347, 1247–1256. (IF: 5.250)
[6]Li Hui-Jing, Zhao Jun-Ling, Chen Yong-Jun, Liu Li, Wang Dong,* Li Chao-Jun.* “Water-promoted direct aerobic oxidation of enol silyl ether to a-hydroxyl ketones without catalyst” Green Chemistry 2005, 7, 61–63. (IF: 5.472)
[7]Li Hui-Jing, Tian Hong-Yu, Chen Yong-Jun, Wang Dong,* Li Chao-Jun.* “Chiral anionic surfactants for asymmetric Mukaiyama aldol-type reaction in water” Journal of Chemical Research 2003, 153–156.
[8]Li Hui-Jing, Tian Hong-Yu, Chen Yong-Jun, Wang Dong,* Li Chao-Jun.* “Novel chiral gallium Lewis acid catalysts with semi-crown ligands for aqueous asymmetric Mukaiyama aldol reactions” Chemical Communications 2002, 2994–2995. (IF: 5.787)
[9] Li Hui-Jing,u Liang-Zhong,* Zhang Shu-Sheng*Synthesis of (N,N-diethylamino)ethyl caproate by using Ti(OBu)4 catalyst. Journal of Qingdao Institute of Chemical Technology 2001, 22, 147–148.
[10] Wu Yan-Chao,* Li Hui-Jing, Liu Li, Demoulin Nicolas, Liu Zhe, Wang Dong, Chen Yong-Jun.* “ Hafnium triflate as an efficient catalyst for direct Friedel-Crafts reaction of chromene hemiacetals” Advanced Synthesis & Catalysis 2011, 353, 907–912. (IF: 5.250)
[11] Wu Yan-Chao,* Li Hui-Jing, Liu Li, Liu Zhe, Wang Dong, Chen Yong- Jun.* “Cascade reaction of β,γ-unsaturated α-ketoesters with phenols in trityl chloride/TFA system. Highly selective synthesis of 4-aryl-2H-chromenes and their applications” Organic & Biomolecular Chemistry 2011, 9, 2868–2877. (IF: 3.451)
[12] Wu Yan-Chao,* Li Hui-Jing, Liu Li, Demoulin Nicolas, Liu Zhe, Wang Dong, Chen Yong-Jun.* “Facile Synthesis of Spiropyrans from Chromene Hemiacetal Esters and Bifunctional Nucleophiles” Synlett, 2011, (11), 1573–1578. (IF: 2.447)
[13] Wu Yan-Chao,* Li Hui-Jing, Yang Hua-Zheng. “A sensitive and highly selective fluorescent sensor for In3+” Organic & Biomolecular Chemistry 2010, 8, 3394–3397. (IF: 3.451)
[14] Wu Yan-Chao,* Li Hui-Jing, Liu Li, Wang Dong, Yang Hua-Zheng, Chen Yong-Jun.* “Efficient construction of pyrazolo[1,5-a]pyrimidine scaffold and its exploration as a new heterocyclic fluorescent platform” Journal of Fluorescence 2010, 18, 357–363. (IF:1.966)
[15] Tian Hong-Yu, Li Hui-Jing, Chen Yong-Jun, Wang Dong,* Li Chao-Jun.* Development of Highly Effective Encapsulating Surfactants for Mukaiyama Aldol Reactions in Water. Industrial & Engineering Chemistry Research 2002, 41, 4523–4527 (IF: 2.071)
[16] Pan Gebo, Li Hui-Jing, Yuan Qunhui, Chen Yongjun,* Wan Lijun,* Bai Chunli. Ordered arrays of semi-crown ligands on an Au(III) electrode surface: In situ STM study. Science in China, Series B: Chemistry. 2004, 47, 320–325. (IF: 1.042)
[17] Xu Liang-Zhong,* Li Hui-Jing, Zhang Shu-Sheng* Studies on syntheses and biological activities of novel triazole compounds containing phosphorodithioate groups. Journal of Qingdao Institute of Chemical Technology 2000, 21, 80–82.
[18] Xu Liang-Zhong,* Li Hui-Jing, The study of 2% Hypertonic abamectin Bla and alphacypermethrin EC. Journal of Qingdao Institute of Chemical Technology 2000, 21, 75–77
[19] Xu Liang-Zhong,* Li Hui-Jing, Zhang Shu-Sheng* Progress of 1,2,4-triazole fungicides. Journal of Qingdao Institute of Chemical Technology 2000, 21, 201–205.
[20] Wu Yan-Chao, Chen Yong-Jun, Li Hui-Jing, Zou Xiao-Mao, Hu Fang-Zhong, Yang Hua-Zheng.* Synthesis of trifluoromethyl-promoted functional pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-d] [1,2,3,5]tetrazine- 4(3H)-ones. Journal of Fluorine Chemistry 2006, 127, 409–416. (IF: 1.719)
[21] Wu Yan-Chao, Liu Li, Li Hui-Jing, Wang Dong, Chen Yong-Jun.* Skraup-Doebner-von Miller quinoline synthesis revisited: Reversal of the regiochemistry for gamma-aryl-beta, gamma-unsaturated alpha-ketoesters Journal of Organic Chemistry 2006, 71, 6592–6595 (IF: 4.002，引用次数34)
[22] Xu Liang-Zhong,* Zhang Shu-Sheng,* Li Hui-Jing, Jiao Kui. Studies on synthesis and biological activities of novel triazole compounds containing 1,3-dioxolane. Chemical Research in Chinese Universities 2002, 18, 284–286. (IF: 0.460)
[23] Zhang Shu-Sheng,* Jiao Kui,* Li Hui-Jing, Chen Hong-Yuan. Spectroscopic and electrochemical studies on the enzyme-catalyzed reaction of PAP-H2O2-HRP. Chemical Journal of Chinese Universities 2000, 21, 710–712. (IF: 0.656)
[24] Xu Liang-Zhong,* Ye Qing-Guo, Li Hui-Jing, Jiao Kui, Zhang Shu-Sheng.* Structure and characterization of O,O-diethylthiophosphoryl- hydrazine o-vanillin Schiff base nickel(II) complex: NiC24H36N4O8P2S2 Journal of Chemical Crystallography 2000, 30, 463–467 (IF: 0.666)
[25]Zhang Shu-Sheng,* Jiao Kui,* Chen Hong-Yuan, Li Hui-Jing. Spectroscopic and electrochemical studies on the MAP-H2O2-HRP voltammetric enzyme-linked immunoassay system. Acta Chimica Sinica 1999, 57, 922–930. (IF: 0.611)
[26] Li Hui-Jing, Guillot Regis, Gandon Vincent. A Gallium-Catalyzed Cycloisomerization/ Friedel−Crafts Tandem. Journées de Chimie Organique Ecole Polytechnique, Palaiseau-21-23 Septembre, 2010.
[27] Li Hui-Jing, Deinzer Max L. New protocols based on tandem mass spectrometry to rapidly and completely sequence natural product – proanthocyanidins. 54th ASMS conference, 2006, Seattle, Washington, USA
[28] Miranda, Cristobal L., Chung Woon-Gye, Li Hui-Jing, Stevens Jan F., Claudia S. Maier. Approach for evaluating the effects of proanthocyanidins on rotenone-induced toxicity in SH-SY5Y neuroblastoma cells. 54th ASMS conference, 2006, Seattle, Washington, USA
[29] Li Hui-Jing, Deinzer Max L. Characterization of proanthocyanidin oligomers in hops by HPLC-APCI-MS-(MS). 53th ASMS conference, 2005, San Antonio, Texas, USA
[30] Li Hui-Jing, Tian Hong-Yu, Liu Li, Chen Yong-Jun, Wang Dong. A novel chiral Ga(III) catalyst for enantioselective aldol reactions in aqueous media. The 24th Annual Meeting of the Chinese Chemical Society. 2004, Apri. 24-27, p01-0-058. Changsha, P. R. China. 
[31]Zhang Shu-Sheng,* Jiao Kui,* Li Hui-Jing. Studies on the enzyme-catalyzed reaction of voltammetric enzyme-linked immunoassay system based on p-aminophenol as substrate. Proceedings of International, Eighth Beijing conference and exhibition on instrumental analysis, 1999, 25-28. Beijing, P. R. China.
著作及译著1. Li Hui-Jing, Deinzer Max L. “Chapter 32-Proanthocyanidins in hops” in Beer in Health and Disease Prevention (Editor(s): Preedy, Victor R. Publisher: Elsevier Inc., Burlington, England), 2009, 333–348.
2. Li Hui-Jing, Deinzer Max L. “Chapter 9-Polyphenolic Compounds in Hops” in Hop Flavor and Aroma (Editor(s): Thomas H. Shellhammer. Publisher: Master Brewers Association of the Americas, Minnesota, USA), 2009, 99–121.
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