标题：吴季辉
人物简介
吴季辉，男，教授，博士生导师。
1982年毕业于中国科学技术大学生物系细胞生物学专业，1988在中国科学院生物物理所获理学硕士学位。
1995.1-1996.1，瑞士苏黎世联邦高工分子生物和生物物理研究所进修核磁实验技术及蛋白质的结构修正方法。
1982.10-1985.8，在中国科学院武汉病毒研究所工作，从事轮状病毒的ds-RNA研究及植物病毒的保存等工作。
1988.10－现在，在中国科学技术大学生命科学学院任教并从事核磁共振和结构生物学的研究工作。
Yunyu Shi and Jihui Wu . (2007) Structural basis of protein–protein interaction studied by NMR. Journal of Structural and Functional Genomics. 8(2-3):67-72. [Full Text] 
Jie Wen, Pei Zhou, Jihui Wu (2012) Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl–methyl NOESY for large proteins Journal of Magnetic Resonance. Available online 9 March 2012 [Full Text] 
Xinxin Li, Kaixian Liu, Fudong Li, Juncheng Wang, Hongda Huang, Jihui Wu,and Yunyu Shi (2012) Structure of the C-terminal tandem BRCT repeats of Rtt107 reveals a critical role in the interaction with γH2A during DNA damage repair . JBC. Published on January 19, 2012 [Full Text]
Yu Qiu, Wen Zhang, Chen Zhao, Yan Wang, Weiwei Wang, Jiahai Zhang, Zhiyong Zhang, Guohong Li, Yunyu Shi, Xiaoming Tu and Jihui Wu (2012)
Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA Biochem. J. (2012) 442 (527–538) [Full Text]
Zhenhua Shao, Fudong Li, Shirley M.-H. Sy, Wei Yan, Zhiyong Zhang, Deshun Gong, Bin Wen, Michael S.Y. Huen, Qingguo Gong, Jihui Wu, Yunyu Shi , (2012) Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure, Journal of Structural Biology,Volume 177, Issue 2, February 2012, Pages 459–468 [Full Text] 
Weiwei Wang, Lijun Wang, Yang Zou, Jiahai Zhang, Qingguo Gong, Jihui Wu, Yunyu Shi* (2011) Cooperation of Escherichia coli Hfq hexamers in DsrA binding, Genes & Development. 25(19):2106-2117. [Full Text] 
Hu H, Liu Y, Wang M, Fang J, Huang H, Yang N, Li Y, Wang J, Yao X, Shi Y, Li G, Xu RM，(2011) Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP. Genes Dev. 25(9):901-906. [Full Text] 
Su Qin, Lei Jin, Jiahai Zhang, Lei Liu, Peng Ji, Mian Wu, Jihui Wu and Yunyu Shi. (2011) Recognition of unmodified histone H3 by the first PHD finger of Bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases MOZ and MORF. Journal of Biological Chemistry, 286(42):36944-36955 [Full Text] 
Jianping Liu, Jiahai Zhang, Qingguo Gong, Peng Xiong, Hongda Huang, Bo Wu, Guowei Lu, Jihui Wu and Yunyu Shi. (2011) Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain. Journal of Biological Chemistry, 286(33):29218-29226 [Full Text] 
Jie Wen, Jihui Wu, and Pei Zhou. (2011) Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins. Journal of Magnetic Resonance 209(1): 94-100 [Full Text] 
Fangming Wu, Yiwei Liu, Zhiqiang Zhu, Hongda Huang, Bo Ding, Jihui Wu, and Yunyu Shi (2011) The 1.9 Å crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones. Journal of Structural Biology. 174(1):213-222 [Full Text] 
Peng Ji, Guang Yang, Jiahai Zhang, Jiawen Wu, Zhengjun Chen, Qingguo Gong, Jihui Wu, Yunyu Shi (2011) Solution structure of the second PDZ domain of zonula occludens 1. Proteins: Structure, Function, and Bioinformatics ,79(4):1342-1346 [Full Text] 
Bin Rui, Tie Shen, Hong Zhou, Jianping Liu, Jiusheng Chen, Xiaosong Pan, Haiyan Liu, Jihui Wu, Haoran Zheng and Yunyu Shi. (2010) A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress. BMC Systems Biology, 4: 122. [Full Text] 
Yiwei Liu#, Hongda Huang#, Bo O. Zhou, Shan-Shan Wang, Yingxia Hu, Xu Li, Jianping Liu, Jianye Zang, Liwen Niu, Jihui Wu, Jin-Qiu Zhou, Maikun Teng, and Yunyu Shi. (2010) Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing. Journal of Biological Chemistry, 285(6):4251-62. [Full Text] 
Xingsheng Wang, Shaojie Zhang, Jiahai Zhang, Xiaojuan Huang, Chao Xu, Weiwei Wang, Zhijun Liu, Jihui Wu, and Yunyu Shi. (2010) A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR. Journal of Biological Chemistry, 285(7):4951-63. [Full Text] 
Xiaojuan Huang, Monique Beullens, Jiahai Zhang, Yi Zhou, Emilia Nicolaescu, Bart Lesage, Qi Hu, Jihui Wu, Mathieu Bollen, and Yunyu Shi. (2009) Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21. Journal of Biological Chemistry, 284(37):25375-87. [Full Text] 
Jingjun Hong , Jiahai Zhang , Zhijun Liu , Su Qin , Jihui Wu and Yunyu Shi. (2009) Solution Structure of S. cerevisiae PDCD5like protein and its promoting role in H2O2-induced apoptosis in yeast. Biochemistry, 48(29):6824-34. [Full Text] 
Zhijun Liu, Jiahai Zhang, Xingsheng Wang, Yanwei Ding, Jihui Wu , Yunyu Shi. (2009) Temperature-induced partially unfolded state of hUBF HMG Box-5: Conformational and dynamic investigations of the Box-5 thermal intermediate ensemble. Proteins: Structure, Function, and Bioinformatics, 77(2):432-47. [Full Text] [Supporting Information] 
Tie Shen, Weiqun Shen, Ying Xiong, Haiyan Liu, Haoran Zheng, Hong Zhou, Bin Rui, Jianping Liu, Jihui Wu, Yunyu Shi. (2009) Increasing the accuracy of mass isotopomer analysis through calibration curves constructed using biologically synthesized compounds. Journal of Mass Spectrometry 44(7):1066-80. [Full Text] 
Ying Liu, Xiqing Wang, Jiahai Zhang, Hongda Huang, Bo Ding, Jihui Wu, and Yunyu Shi. (2008) Structural Basis and Binding Properties of the Second Bromodomain of Brd4 with Acetylated Histone Tails. Biochemistry, 47 (24): 6403–6417 [Full Text] 
Jiangxin Liu, Jiahai Zhang, Yinshan Yang, Hongda Huang, Weiqun Shen, Qi Hu, Xingsheng Wang, Jihui Wu, and Yunyu Shi. (2008) Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor. Protein Science. 17:1003-1014. [Full Text]