标题：汪海健
个人简历
2006.4-至今，复旦大学生命科学学院与生物医学研究院，副教授；
2004.7-2006.3，复旦大学生命科学学院与生物医学研究院，讲师；
2003.7-2004.6，国家人类基因组北方研究中心，研究助理；
2000.9-2003.6，军事医学科学院放射与辐射医学研究所，细胞生物学专业人类与医学遗传学方向博士生，获理学博士学位；
1997.9-2000.6, 南京农业大学动物医学院，预防兽医学专业分子病毒学方向硕士生，获农学硕士学位；
1993.9-1997.6, 湖北农学院动物科学系，畜牧兽医专业本科生，获农学学士学位；
研究方向
研究领域包括复杂疾病的遗传易感性，比较与进化药物基因组学，以及分子水平人类适应性进化。目前研究方向为P450和ABC转运体等药物代谢酶的进化与功能基因组学。对疾病的遗传分析，不仅需要从横向的空间上分析不同群体或个体的遗传变异对疾病谱和易感性的影响，而且需要在纵向的进化历史中，把疾病的自然史和人类的分子适应性进化结合起来，考察人类起源迁移的群体历史中，动态变化的环境风险因素对疾病相关基因的达尔文分子选择。运用群体遗传学与分子进化的原理与方法，结合分子与细胞生物学的实验手段，以及基于家系或群体的疾病连锁与关联分析，从多个水平研究“疾病遗传与人类进化”，不仅对探询人类进化的自然史有重要理论意义，而且对了解包括肿瘤与心脑血管疾病等重大复杂疾病的病因学，以及疾病谱和药物反应性的群体差异，并最终促进疾病群体预防和个体化治疗，亦有重大现实意义。 
获奖情况
2005年全国优秀博士论文提名;
2005年军队科技进步一等奖（第五完成人）；
2005年北京市科技进步一等奖（第八完成人）；
2005年中华医学科技二等奖（第八完成人）；
2005年第八届“北京青年优秀科技论文”一等奖；
1998年南京农业大学“品学兼优研究生”
代表性论文和专著
（以发表时间为序，* 并列第一作者; §并列通讯作者）：
1. Haijian Wang*, Keyue Ding*, Yang Zhang, Li Jin, Iftikhar J. Kullo, Fuchu He. Comparative and Evolutionary Pharmacogenetics of ABCB1: Complex Signatures of Positive Selection on Coding and Regulatory Regions. (Pharmacogenet Genomics 2007, in press; SCI 2005 IF = 5.882) 
2. Haijian Wang, Bingtao Hao, Xiaoping Chen, Naiqing Zhao, Gang Cheng, Yan Jiang, Yang Liu, Chengzhao Lin, Wen Tan, Daru Lu, Qingyi Wei, Li Jin, Dongxin Lin§, and Fuchu He§. Beta-2 adrenergic receptor gene (ADRB2) polymorphism and risk for lung adenocarcinoma: A case-control study in a Chinese population. Cancer Lett. 2006; 240: 297-305. (SCI 2005 IF = 3.049)
3. Haijian Wang, Yan Jiang, Yang Liu, Chengzhao Lin, Gang Cheng, Xiaoping Chen, Bingtao Hao, Wen Tan, Dongxin Lin§, and Fuchu He§. CYP2J2*7 single nucleotide polymorphism in a Chinese population. Clin Chim Acta 2006, 365:125-8. (SCI 2005 IF = 2.149)
4. Xiaoping Chen, Haijian Wang, Weimin Xie, Renxiang Liang, Zhongliang Wei, Lianteng Zhi, Xiumei Zhang, Bingtao Hao, Shaofei Zhong, Gangqiao Zhou, Lingqiang Zhang, Xue Gao, Yunping Zhu and Fuchu He. Association of CYP1A2 genetic polymorphisms with hepatocellular carcinoma susceptibility: a case-control study in a high-risk region of China. Pharmacogenet Genomics 2006; 16:219-227. (SCI 2005 IF = 5.882)
5. Bingtao Hao, Xiaoping Miao, Yi Li, Xuemei Zhang, Tong Sun, Gang Liang, Yanlin Zhao, Yifeng Zhou, Haijian Wang, Xiaoping Chen, Lingqiang Zhang, Wen Tan, Qingyi Wei, Dongxin Lin, and Fuchu He. A Novel T-77C Polymorphism in XRCC1 Contributes to Diminished Promoter Activity and Increased Lung Cancer Susceptibility. (Oncogene 2006; 25: 3613-20, SCI 2005 IF = 6.872)
6. Xiaoping Chen, Liqing Wang, Lianteng Zhi, Gangqiao Zhou, Haijian Wang, Xiumei Zhang, Bingtao Hao, Yunping Zhu Zeneng Cheng, Fuchu He. The G-113A polymorphism in CYP1A2 affects the caffeine metabolic ratio in a Chinese population. Clin Pharmacol Ther. 2005; 78: 249-59. (SCI 2005 IF = 7.526)
7. Haijian Wang, Bingtao Hao, Kaixin Zhou, Xiaoping Chen, Songfeng Wu, Gangqiao Zhou, Yunping Zhu, and Fuchu He. Linkage disequilibrium and haplotype architecture for two ABC transporter genes (ABCC1 and ABCG2) in Chinese population: implications for pharmacogenomic association study. Ann Hum Genet. 2004, 68: 563-573. (SCI 2003 IF = 3.102)
8. Bingtao Hao, Haijian Wang, Kaixin Zhou, Yi Li, Xiaoping Chen, Gangqiao Zhou, Yunping Zhu, Xiaoping Miao, Wen Tan, Qingyi Wei, Dongxin Lin§, and Fuchu He§. Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma. Cancer Res. 2004, 64(12): 4378-4384. (SCI 2003 IF = 8.649)
9. Haijian Wang*, Wen Tan*, Bingtao Hao, Xiaoping Miao, Gangqiao Zhou, Fuchu He§, and Dongxin Lin§. Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active Cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer Res. 2003, 63(22): 8057-8061. (SCI 2002 IF = 8.318)
10. Guo-Lin Chen*, Haijian Wang*, Wei Wang, Zhen-Hua Xu, Gan Zhou, Fuchu He§, and Hong-Hao Zhou§. Histamine N-methyltransferase gene polymorphisms in Chinese and their relationship with enzyme activity in erythrocyte. Pharmacogenet; 2003, 13 (7): 389-397. (SCI 2002 IF = 5.540)
11. Heyi Yang, Haijian Wang, Jie Wang, Yun Cai, Gangqiao Zhou, Fuchu He and Xiaohong Qian. Multiplex single-nucleotide polymorphism genotyping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Biochem 2003; 314(1): 54-62. (SCI 2002 IF = 2.370)
12. 汪海健, 贺福初. 生物异源物传感系统研究进展. 生命的化学. 2003; 23(2): 97-99.[1]