标题：有机合成现代方法
图书信息
出版社: 世界图书出版公司; 第1版 (2008年10月1日)
外文书名: Modern Methods of Organic Synthesis
丛书名: 经典英文化学教材系列
平装: 493页
正文语种: 简体中文, 英语
开本: 16
ISBN: 9787506292702
条形码: 9787506292702
尺寸: 25.8 x 18.2 x 2.8 cm
重量: 821 g
作者简介
作者：(英国)卡如萨 (Carruthers.W.)
内容简介
《有机合成现代方法(第4版)》初版于1971年，1978年出了第2 版，1986年出了第3版，1987年至2002年，《有机合成现代方法(第4版)》共重印9次，2004年第4版，2005年重印出版，由此可见，这是一部很受欢迎的经典教科书。书中介绍有机合成化学的基本原理，重点阐述了近代有机化学的新方法，新试剂和新理论在有机合成中的应用。在经典有机合成的框架内引入现代方法，概念清晰，引证丰富，重点突出，文字精炼。论述上注意由浅入深，不同层次的读者均可从中受益。
目录
Preface to the first edition
Preface to the fourth edition
1 Formation of carbon-carbon single bonds
1.1 Main-group chemistry
1.1.1 Alkylation of enolates and enamines
1.1.2 Conjugate addition reactions of enolates and enamines
1.1.3 The aldol reaction
1.1.4 Asymmetric methodology with enolates and enamines
1.1.5 0rganolithium reagents
1.1.6 0rganomagnesium reagents
1.1.7 Organozinc reagents
1.1.8 Allylic organometallics of boron, silicon and tin
1.2 Transition-metal chemistry
Problems
1.2.1 Organocopper reagents
1.2.2 Organochromium chemistry
1.2.3 Organocobalt chemistry
1.2.4 0rganopalladium chemistry
2 Formation of carbon-carbon double bonds
2.1 [3-Elimination reactions
2.2 Pyrolytic syn eliminations
2.3 Fragmentation reactions
2.4 Alkenes from hydrazones
2.5 Alkenes from 1,2-diols
2.6 Alkenes from alkynes
2.7 The Wittig and related reactions
2.8 Alkenes from sulfones
2.9 Alkenes using titanium or chromium reagents
2.10 Alkene metathesis reactions
Problems
3 Pericyclic reactions
3.1 The Diels-Alder cycloaddition reaction
3.1.1 The dienophile
3.1.2 The diene
3.1.3 Regiochemistry of the Diels-Alder reaction
3.1.4 Stereochemistry of the Diels-Alder reaction
3.1.5 Intramolecular Diels-Alder reactions
3.1.6 The retro Diels-Alder reaction
3.1.7 Asymmetric Diels-Alder reactions
3.2 [2+2] Cycloaddition reactions
3.3 Cycloaddition reactions with allyl cations and allyl anions
3.4 1,3-Dipolar cycloaddition reactions
3.5 The ene reaction
3.6 [3,3]-Sigmatropic rearrangements
3.6.1 The Cope rearrangement
3.6.2 The Claisen rearrangement
3.7 [2,3]-Sigmatropic rearrangements
3.8 Electrocyclic reactions
Problems
4 Radical and carbene chemistry
4.1 Radicals
4.1.1 Radical abstraction reactions
4.1.2 Radical addition reactions
4.2 Carbenes
Problems
Functionalization of alkenes
5.1 Hydroboration
5.1.1 Reactions of organoboranes
5.2 Epoxidation and aziridination
5.2.1 Epoxidation
5.2.2 Asymmetric epoxidation
5.2.3 Aziridination
5.3 Dihydroxylation
5.3.1 Dihydroxylation with osmium tetroxide
5.3.2 Other methods of dihydroxylation
5.3.3 Amino-hydroxylation
5.4 Oxidative cleavage
5.5 Palladium-catalysed oxidation of aikenes
Problems
6 Oxidation
6.1 Oxidation of hydrocarbons
6.1.1 Alkanes
6.1.2 Aromatic hydrocarbons
6.1.3 Alkenes
6.2 Oxidation of alcohols
6.2.1 Chromium reagents
6.2.2 Oxidation via alkoxysulfonium salts
6.2.3 Manganese reagents
6.2.4 Other metal-based oxidants
6.2.5 Other non-metal-based oxidants
6.2.6 oxidation to carboxylic acids or esters
6.3 Oxidation of ketones
6.3.1 a,~~3-Unsaturated ketones
6.3.2 a-Hydroxy-ketones
6.3.3 Baeyer-Villiger oxidation of ketones
Problems
7 Reduction
7.1 Catalytic hydrogenation
7.2 Reduction by dissolving metals
7.3 Reduction by hydride-transfer reagents
7.3.3 Derivatives of lithium aluminium hydride and sodium
borohydride
7.3.4 Mixed lithium aluminium hydride-aluminium chloride
reagents
7.3.5 Diisobutylaluminium hydride (DIBAL-H)
7.3.6 Sodium cyanoborohydride and sodium
triacetoxyborohydride
7.3.7 Borane and derivatives
7.4 Other methods of reduction
7.4.1 Enzyme catalysed
7.4.2 Wolff-Kishner reduction
7.4.3 Reductions with diimide
7.4.4 Reductions with trialkylsilanes
Problems
Answers to problems
Index