标题：异噻唑啉酮
基本信息
中文名称:异噻唑啉酮 
中文别名:凯松防腐剂;5-氯-2-甲基-1-异噻唑啉-3-酮和2-甲基-1-异噻唑啉-3-酮的混合物;(5-氯-2-甲基-4-异噻唑-3-酮)+(2-甲基-4-异噻唑-3-酮);卡松[1]
英文名称:Kathon 886
英文别名:Kathon biocide; 5-Chloro-2-methyl-3(2H)-isothiazolone with 2-methyl-3(2H)-isothiazolone; 5-Chloro-2-methyl-4-isothiazolin-3-one; Isothiazolinone; 5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone; 2-methyl-1,2-thiazol-3(2H)-one - 5-chloro-2-methyl-1,2-thiazol-3(2H)-one (1:1)
CAS:55965-84-9;96118-96-6
EINECS:-
分子式:C8H9ClN2O2S2
分子量:264.7523
物化性质
沸点： 200.2°C at 760 mmHg 
闪点： 74.9°C 
蒸汽压： 0.328mmHg at 25°C 
InChI： InChI=1/C4H4ClNOS.C4H5NOS/c1-6-4(7)2-3(5)8-6;1-5-4(6)2-3-7-5/h2H,1H3;2-3H,1H3 
一、性能与用途异噻唑啉酮主要由5-氯-2-甲基-4-异噻唑啉-3-酮（CMI）和 2-甲基-4-异噻唑啉-3-酮（MI）组成。异噻唑啉酮是通过断开细菌和藻类蛋白质的键而起杀生作用的。异噻唑啉酮与微生物接触后，能迅速地不可逆地抑制其生长，从而导致微生物细胞的死亡，故对常见细菌、真菌、藻类等具有很强的抑制和杀灭作用。杀生效率高，降解性好，具有不产生残留、操作安全、配伍性好、稳定性强、使用成本低等特点。能与氯及大多数阴、阳离子及非离子表面活性剂相混溶。高剂量时，异噻唑啉酮对生物粘泥剥离有显著效果。
异噻唑啉酮是一种广谱、高效、低毒、非氧化性杀生剂。广泛运用于油田、造纸、农药、切削油、皮革、油墨、染料、制革等行业。
二、技术指标：行业标准HG/T 3657—2008水处理剂 异噻唑啉酮衍生物 
项 目指 标​1类2类​外 观棕黄色透明液体淡黄或淡绿色透明液体活性物含量/% 14.0～15.01.50～1.80PH值2.0-4.0 2.0-5.0密度(20℃)g/cm1.26～1.321.02～1.05CMI/MI（质量百分数）/%2.5-3.42.5-3.4三、使用方法异噻唑啉酮2类产品作粘泥剥离剂时，投加浓度150-300mg/l；作杀菌剂时，每隔3-7天投加一次，投加剂量80~100mg/L。能与氯气等氧化型杀菌剂同时使用，不能用于含硫化物的冷却水系统。异噻唑啉酮季胺盐复合使用效果较佳。
异噻唑啉酮做工业杀菌防霉剂使用时，一般浓度为0.05-0.4%
四、包装与贮存异噻唑啉酮塑料桶包装，每桶25kg或根据用户要求确定；贮于室内阴凉处，贮存期十个月。
五、安全防护异噻唑啉酮有腐蚀性、对皮肤和眼睛有刺激性，操作时应配备防护眼镜和胶手套，一旦接触皮肤、眼睛时，应立即用大量清水冲洗。
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异噻唑啉酮的合成
异噻唑啉酮的合成从基础原料出发，分三步。
1.二硫代二丙酸二甲酯的制备 
2.二甲基二硫代二丙酰胺的制备
3.异噻唑啉酮的制备
Isothiazolinones
Isothiazolinones
【CAS】26172-55-4, 2682-20-4 Molecular weight: 115.16 
Properties:　Isothiazolinones is composed of 5-chloro-2-methyl-4-thiazoline-3-ketone (CMI) and 2-methyl-4-thiazoline-3-ketone (MI). The bactericidal effect of Isothiazolinones is carried out through breaking the bond between bacteria and algae protein. When contacted with microbes, Isothiazolinones can quickly inhibit their growth, thus leading to death of these microbes. Isothiazolinones has strong inhibition and biocidal effects on ordinary bacteria, fungi and alga, and has many advantages such as high biocidal efficiency, good degradation, no residual, safety in operation, good compatibleness, good stabilization, low cost in operation. 
Isothiazolinones can mix with chlorine and most cation, anion, and non-ionic surfactants. When used at high dosage, its biosludge stripping effect is excellent. 
Isothiazolinones is a kind of fungicidal with properties of broad spectrum, high efficiency, low toxicity and non-oxidative, it is the ideal biocidal in industrial circulating cool water system and in wastewater treatment in oilfield, papermaking, pesticide, cutting oil, leather, detergent and cosmetics etc.. 
Specification:　Notes: 2%, 4% and 8% or any concentration can be supplied on demands.
itemsindex​Grade IGrade II​AppearanceAmber transparent liquidLight yellow or light green transparent liquidActive content % 14.0 min1.50 minpH value（as it）1.0-4.02.0-5.0Density （20℃）g/cm31.25 min1.02 minCMI/MI (wt %)2.5-4.02.5-4.0Usage:　When used as sludge stripper for grade II, the dosage of 150-300mg/L is preferred, when used as boicide, the dosage of 80-100mg/L is preferred, and charges every 3-7 days. No used together with oxidative fungicidal such as chlorine, and no used in cooling water system containing sulfur. When used together with quaternary amine, the effect will be better. When used as industrial fungicide, the dosage of 0.05-0.4% is preferred. 
Package and Storage:　25kg in plastic barrel, or confirmed by clients. Storage for ten months in room shady and dry place. 
Safety Protection:　Corrosive, Avoid contact with eye and skin, Wear splash resistant safety goggles and rubber glores.once contacted, flush with water. 
Keywords: Isothiazolinones,Isothiazolinones China