标题：杜大明
个人履历
1989年获郑州大学理学学士学位。
1992年获南开大学理学硕士学位。
1995年获南开大学理学博士学位。
1995-1997年山东大学讲师。
1997-1999年山东大学副教授。
1996-1997年香港中文大学访问学者。
1998-1999年香港科技大学博士后。
1999-2001年北京大学博士后。
2001-2008年北京大学化学学院副教授。
2008年起北京理工大学化工与环境学院教授。
研究兴趣和领域
1. 新型手性配体、有机催化剂设计合成及不对称催化反应研究，发展不对称合成的先进方法学。
2. 化学药物及药物中间体的合成。
代表性论文和专著
1. Yang, W.; Du, D. M.* Chiral squaramide-catalyzed highly diastereo- and enantioselective direct Michael addition of nitroalkanes to nitroalkenes. Chem. Commun. 2011, 47(47), 12706–12708.
2. Yang, W.; Du, D. M.* Chiral squaramide-catalyzed highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes. Adv. Synth. Catal. 2011, 353(8), 1241–1246.
3. Yang, W.; Du, D. M.* Highly enantioselective Michael addition of nitroalkanes to chalcones using chiral squaramides as hydrogen bonding organocatalysts. Org. Lett. 2010, 12(23), 5450–5453.
4. Liu, H.; Du, D. M.* Development of diphenylamine-linked bis(imidazoline) ligands and their application in asymmetric Friedel-Crafts alkylation of indole derivatives with nitroalkenes. Adv. Synth. Catal. 2010, 352(7), 1113–1118.
5. Guo, Q. S.; Du, D. M.*; Xu, J. The development of new double axially chiral phosphoric acids and their catalytic asymmetric transfer hydrogenation of quinolines. Angew. Chem. Int. Ed. 2008, 47(4), 759–762. 
6. Zhou, W. M.; Liu, H.; Du, D. M.* Organocatalytic highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes. Org. Lett. 2008, 10(13), 2817–2820.
7. Liu, H.; Lu, S. F.; Xu, J.; Du, D. M.* Asymmetric Friedel-Crafts alkylation of electron-rich N-heterocycles with nitroalkenes catalyzed by diphenylamine-tethered bis(oxazoline) and bis(thiazoline)-Zn(II) complexes. Chem. Asian J. 2008, 3(7), 1111–1121.
8. Liu, H.; Xu, J.; Du, D. M.* Asymmetric Friedel-Crafts alkylation of methoxyfuran with nitroalkenes catalyzed by diphenylamine-tethered bis(oxazoline)-Zn(II) complexes. Org. Lett. 2007, 9(23), 4725–4728.
9. Lu, S. F.; Du, D. M.*; Xu, J.; Zhang, S. W. Asymmetric conjugate addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) zinc complexes. J. Am. Chem. Soc. 2006, 128(23), 7418-7419.  
10. Du, D. M.*; Fang, T.; Xu, J.; Zhang, S. W. Structurally well-defined, recoverable C3-symmetric tris(b-hydroxy phosphoramide) catalyzed enantioselective borane reduction of ketones. Org. Lett. 2006, 8(7), 1327-1330. 
11. Lu, S. F.; Du, D. M.*; Xu, J. Enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II) complex. Org. Lett. 2006, 8(10), 2115-2118. 
12. Du, D. M.*; Lu, S. F.; Fang, T.; Xu, J.* Asymmetric Henry reaction catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) complexes: metal-controlled reversal of enantioselectivity. J. Org. Chem. 2005, 70(9), 3712-3715.
13. Fang, T.; Du, D. M.*; Lu, S. F.; Xu, J.* Synthesis of C3-symmetric tris(b-hydroxy amide) ligands and their Ti(IV) complex-catalyzed enantioselective alkynylation of aldehydes. Org. Lett. 2005, 7(11), 2081-2084. 
14. Du, D. M.; Carlier, P. R.* Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer’s disease. Current Pharm. Design 2004, 10(25), 3141-3156.  
15. Carlier, P. R.*; Du, D. M.; Han, Y. F.; Liu, J.; Perola, E.; Williams, I. D.; Pang, Y. P. Dimerization of an inactive fragment of Huperzine A produces a drug with twice the potency of the natural product. Angew. Chem. Int. Ed. 2000, 39(10), 1775-1777.
16. Yang, X. P.; Du, D. M.; Li, Q.; Mak, T. C. W.; Wong, H. N. C.*  Synthesis, structure and inclusion properties of 1,4,15,18-tetrahedro-1,4,15,18-tetraoxodibenzo[b,h]tetraphenylene.  Chem. Commun. 1999, (16), 1607-1608.