标题：单自兴
教学情况
讲授本科生课程："元素有机化学"，"精细合成技术"，"现代合成技术"
讲授硕士研究生课程：,"元素有机化学进展","不对称合成化学"，"手性化合物化学"
指导博士和硕士研究生近20多人
2000年以来主持的主要科研项目
1．新型手性双官能Lewis酸催化的不对称反应研究
国家自然科学基金, 2007.1-2009.12, 项目主持人
2．新型手性催化剂的开发及在不对称合成中的应用研究
国家自然科学基金, 2004.1-2006.12, 项目主持人
3．固态超分子体系介入的不对称反应研究
国家自然科学基金, 2000.1-2002.12, 项目主持人
4．广谱抗炎手性药物(S)-(+)-布洛芬的制备方法学研究
湖北省科委重点科研项目,1998.1-2000.12, 项目主持人.
参加国家自然科学基金，国际合作项目等多项。
获奖情况
有机硼化合物的制备、性质、结构表征及其在有机合成中的应用
赵德杰, 单自兴*，黄世文，湖北省自然科学二等奖(2000) (*通讯联系人)
国际学术会议邀请报告：
Convenient Preparation of Enantiopure 1,1"-Bi-2-naphthols and Asymmetric Reactions Mediated by 1,1"-Bi-2-naphtholborane Derivatives
Zixing Shan，The Invited Lecture on the 15th International Symposium on Chirality  (Chirality 2003; ISCD-15), 2003, Shizuoka, Japan.
专著
绿色精细化工导论， 贡长生，单自兴等编著，化学工业出版社， 2005年第一版
2000年后授权的发明专利（六项）： 
1．螯合手性硼酸酯及其制备方法和用途
单自兴，刘德军，褚运波，中国发明专利，ZL 03 1 18710.2 （2006）
2．100％ee的(R)- 或(S)-1,1&cent;-联-2-萘酚的制备方法
单自兴，熊  英, 中国发明专利，ZL 200410012746.0 （2005）
3．L-(+)-2-氨基-1-对硝基苯基-1,3-丙二醇的酮缩合物的制备方法
单自兴,万波勇,王国平, 中国发明专利：ZL 00114346.8 (2004)
4．(S)-布洛芬的制备方法
单自兴，万波勇，中国发明专利：ZL 01106592.3 (2003)
5．一种(S)-布洛芬的制备方法
单自兴，万波勇，中国发明专利：ZL 01114245.6 (2003)
6．高对映纯(R)-(+)-和(S)-(-)-1,1&cent;-联-2-萘酚制备新方法
单自兴,王国平,段  标,赵德杰，中国发明专利：ZL 93103325.x（2000）
正在审查中的发明专利五项（略）
发表论文
近年代表性论文 (2003-2006, SCI)：
1  Chiral Borate Esters in Asymmetric Synthesis 5: Asymmetric Reduction of Oxime Ethers Promoted by Chiral Spiroborate Esters with an O3BN Framework 
Yunbo Chu, Zixing Shan, Dejun Liu, Nannan Sun, J. Org. Chem. 2006, 71(10)，3998
2  Chiral Diols: A New Class of Additives for Direct Aldol Reaction Catalyzed by L-proline
Yan Zhou, Zixing Shan, J. Org. Chem. 2006, accepted
3  Selective Oxidation of Polyfunctional 2-Amino-1,3-propanediol Derivatives
Zixing Shan and Guojian Lu, J. Org. Chem. 2004, 69(10), 3593
4  Chiral Borate Esters in Asymmetric Synthesis: 6. Hydrolytically Stable Tricoordinated Chiral Bicyclodiboronate Ester: Synthesis, Structure Characterization and Theoretical Investigation 
Yan Zhou, Zixing Shan, Boshan Wang, Peng Xie, Organometallics 2006, 25 (20), 4917
5  Chiral Borate Esters in Asymmetric Synthesis 4: Chiral spiroborate esters catalyzed highly enantioselective direct aldol reaction
Yan Zhou, Zixing Shan, Tetrahedron, 2006, 62(10), 5692
6  Convenient Preparation of Enantiopure 1,1&cent;-Bi-2-anphthols via Inclusion Complexation of (1S,2S)-N-Benzyl-N,N-dimethyl- [1,3-dihydroxyl-1-(4&cent;- nitrophenyl)]-2-propylammonium Chloride
Ha Wuzu, Shan Zixing*，Tetrahedron: Asymmetry. 2006, 17, 854 
7  (R)- or (S)-Bi-2-naphthol Assisted, L-Proline Catalyzed Direct Aldol Reaction
Yan Zhou, Zixing Shan, Tetrahedron: Asymmetry. 2006, 17(11)，1671
8  Synthesis of Spirobiindanes via Bis-cyclization Reaction of the 1,5-diaryl-3-pentanones Catalyzed by Heteropoly Acids
Kun.Lan, Zixin.Shan and Shao Fan, Tetrahedron Lett, 2006, 47, 4343
9  Highly Chemoselective Synthesis of 1,2,3,4,5-Pentasubstituted Cyclohexanols under Solvent-free Condition
Luo Xinxiang, Shan Zixing, Tetrahedron Lett. 2006, 47, 5623
10  Chiral Borate Esters in Asymmetric Synthesis 2: Asymmetric Borane Reduction of Prochiral Ketones in the Presence of a Chiral Spiroborate Ester
Liu D. J., Shan Z. X., Zhou Y., Qin J. G. Helv. Chim. Acta, 2004, 87(9), 2310.
11  A new and practical method for preparing enantiopure 1,1&cent;-bi-2-nanphthol &frac34;&frac34; resolution of racemic 1,1&cent;- bi-2-nanphthol using threo-(1S,2S)-2-amino-1-(4&cent;-nitrophenyl)-1,3-propanediol cyclohexanone condensate
Dejun Liu, Zixing Shan*, Fei Liu, Chunguang Xiao, Guojian Lu and Jingui Qin, Helv. Chim. Acta, 2003, 86(1), 157.
12  Chiral Borate Esters in Asymmetric Synthesis 1: The First Asymmetric Reaction Catalyzed by Chiral Spiroborate Esters with a O3BN Framework
Liu D. J., Shan Z. X., Qin J. G., Chin. J. Chem., 2004, 22(11), 1336
13  A rapid preparation, properties and structure of diastereomeric 1,1&cent;-bi-2-naphtholboric acid (S)-proline anhydrides
Zixing Shan*, Shimin Liu, Dejun Liu, Chin. J. Chem. 2003, 21(10), 1373
14  Preparation and Properties of Chiral Spiroborate Esters with a O3BN Framework
Zixing Shan, Yan Zhou, Dejun Liu, Wuzu Ha, Synth. React. Inorg. Metal-org. Nono-Metal Chem. 2005, 35(4), 275
15  手性硼酸酯介入的不对称合成 3: 前手性亚胺在(R)-或(S)-1,1&cent;-联-2-萘酚硼酸-(S)-脯氨酸衍生物存在下的不对称催化还原