标题：吴佳妍
简介
  职    称: 副研究员  
职    务: 硕士生导师  
研究方向:  生物信息学
学历:
2000年, 沈阳化工学院, 精细化工学士
2005年, 吉林大学, 物理化学博士 
研究工作经历:
2000年8月--2005年6月,吉林大学,博士生 (指导教授: 中国科学院院士孙家钟教授)
2005年7月--2006年9月,美国Emory大学,博士后 (指导教授: 美国国家艺术与科学院院士Joel M. Bowman教授)
2006年10月--至今 中科院北京基因组研究所，副研究员 
主要研究领域：
吴佳妍博士2000年起在吉林大学攻读博士学位，主要进行大气中重要化学反应的机理研究，在ChemPhysChem，Journal of Chemical Physics, Journal of Computational Chemistry和Chem. Phys. Lett.等专业杂志发表论文十余篇。2004年起对生物化学中酶催化反应的微观动力学进行了研究，采用量子化学计算方法阐述酶的催化性质和反应机理。2005年后，在美国Emory大学Cherry Logan Emerson科学计算中心，主要致力于MULTIMODE化学计算软件的研究和开发，该软件是世界上唯一一款专门用于全局全维势能面的振转能级计算和红外光谱解析的计算软件。2006年底，任职于中国科学院北京基因组研究所，主要从事生物信息学和计算生物学等方面的研究。
目前的研究工作主要有两方面：（1）以生物数据分析和算法设计为主的生物信息学研究；（2）基因组稳定性与基因变异规律研究中的数据挖掘和信息处理，主要内容为DNA修复机制、细胞周期和细胞凋亡相关基因的表达与调控。 
代表论著：
Jiayan Wu, Xinchuan Huang, Stuart Carter and Joel M. Bowman, Variational calculations of vibrational energies of CH4 using an ab initio potential, Chemical Physics Letters, 426, 285 (2006) 
Jia-yan Wu, Jing-yao Liu, Ze-sheng Li, Chia-chung Sun, Theoretical Study of the Reactions of CF3OCHF2 with the Hydroxyl Radical and the Chlorine Atom, ChemPhysChem, 5, 1336, (2004) 
Jia-yan Wu, Jing-yao Liu, Ze-sheng Li, Chia-chung Sun, Dual-level direct dynamics studies for the reactions of CH3OCH3 and CF3OCH3 with the OH radical, Journal of Chemical Physics, 118, 10986, (2003) 
Jia-yan Wu, Jing-yao Liu, Ze-sheng Li, Xu-ri Huang, Chia-chung Sun, Dual-Level Direct Dynamics Studies for the Reactions of Dimethyl Ether with Hydrogen Atom and Methyl Radical, Journal of Computational Chemistry, 24, 593, (2003) 
Jia-yan Wu, Jing-yao Liu, Ze-sheng Li, Xu-ri Huang, Chia-chung Sun, Theoretical study and rate constant calculation for the F + CHFO reaction, Chemical Physics Letters, 369, 504, (2003) 
Jia-yan Wu, Jing-yao Liu, Ze-sheng Li, Xu-ri Huang, Chia-chung Sun, Direct ab initio dynamics calculations of the reaction rates for the hydrogen abstraction reaction Cl+ HC(O)F?HCl +CFO, Physical Chemistry Chemical Physics, 4, 2927, (2002) 
吴佳妍，刘靖尧，李泽生，黄旭日，孙家钟，从头算直接动力学研究反应PCl3 + H ? PCl2 + HCl的速率常数, 高等学校化学学报，12, 263, (2002) 
Amit R. Sharma, Jiayan Wu*, Bastiaan J. Braams, Stuart Carter, Ralf Schneider, Joel M. Bowman, Potential energy surface and MULTIMODE vibrational analysis of C2H3+, Journal of Chemical Physics, 125, 224306, (2006) 
Hui Zhang, Jia-yan Wu, Ze-sheng Li, Jing-yao Liu, Li Sheng and Chia-chung Sun, Dual-level Direct Dynamics Studies on the Reaction Cl + CHBr2Cl, Journal of Computational Chemistry, 26, 1421, (2005) 
Hui Zhang, Jia-yan Wu, Ze-sheng Li, Jing-yao Liu, Li Sheng and Chia-chung Sun, Theoretical Studies on the Reaction OH + CH3SiH2CH3, Journal of Molecular Structure: THEOCHEM, 728, 25, (2005) 
Yue-meng Ji, Jia-yan Wu, Jing-yao Liu, Ze-sheng Li and Chia-chung Sun, Theoretical Study and Rate Constants Calculation for the ClCH2OH + Cl Reaction, Chemical Physics Letters, 417, 345, (2006) 
刘靖尧，吴佳妍，李泽生，黄旭日，孙家钟，直接动力学方法研究反应NCl3 + H ? NCl2 + HCl的速率常数，高等学校化学学报，12, 300, (2002) 
Jing-yao Liu, Ze-sheng Li, Jia-yan Wu, Zhi-gang Wei, Gang Zhang, Chia-chung Sun, Theoretical study and rate constant calculation of the CH2O+CH3 reaction, Journal of Chemical Physics, 119, 7214, (2003) 
Yuan Zhang, Ze-Sheng Li, Jia-yan Wu, Miao Sun, Qing-Chuan Zheng, Chia-Chung Sun, Homology modeling and SN2 displacement reaction of ?uoroacetate 3 dehalogenase from Burkholderia sp. FA1, Biochemical and Biophysical Research Communications, 325, 414, (2004) 
Hui Zhang, Ze-sheng Li, Jia-yan Wu, Jing-yao Liu, Li Sheng and Chia-chung Sun, Dual-level Direct Dynamics Studies on the Reactions of OH radicals with SiH3CH3 and SiH4, Chemical Physics Letters, 409, 355, (2005) 
Bo Li, Jing-yao Liu, Ze-sheng Li, Jia-yan Wu, Chia-chung Sun, Theoretical studies on dynamics and thermochemistry of the reactions CF3CHCl2+Cl?CF3CCl2+HCl and CF3CHFCl+Cl?CF3CFCl+HCl, Journal of Chemical Physics, 120, 6019, (2004) 
Ying Wang, Jing-yao Liu, Ze-sheng Li, Jia-yan Wu, Li Wang and Chia-chung Sun, Ab initio direct dynamics studies on the reactions of Chlorine atom with CH3-nClnCHO (n=1-3), Chemical Physics, 314 , 329, (2005) 
Hui Zhang, Jing-yao Liu, Ze-sheng Li, Li Sheng, Jia-yan Wu and Chia-chung Sun, Ab Initio Direct Dynamics Studies on the Reaction Br + SiH4, Chemical Physics Letters, 405, 240, (2005) 
Ying Wang, Jing-yao Liu, Ze-sheng Li, Li Wang, Jia-yan Wu, and Chia-chung Sun, Direct dynamics study on hydrogen abstraction reaction of CF3CF2CH2OH with OH radical, Journal of Physics Chemical A, 110, 5853, (2006)