标题：巢晖
个人简介
巢晖（Hui Chao），男，1970年3月出生，籍贯湖南汨罗，理学博士，教授，博士生导师。[1]
学术简历
学士（1988-1992）：湖南科技大学化学化工学院；  
硕士（1994-1997）：南开大学化学学院；
博士（1997-2000）：中山大学化学与化学工程学院；
访问学者 (2000-2003)：香港科技大学化学系；
博士后（2004-2005）：美国Texas A&M大学化学系；
讲师（2000-2002）、副教授（2002-2007）：中山大学化学与化学工程学院；
教授（2008-至今 ）：中山大学化学与化学工程学院；
2002年6月被遴选为中山大学无机化学专业/化学生物学专业硕士生导师；
2005年-至今：光电材料与技术国家重点实验室固定研究人员。
科研方向
1.金属配合物与DNA/RNA相互作用研究（包括DNA/RNA结构识别、光断裂及转录抑制）。
2.配合物超分子体系光电转换和光致电子与能量转移调控研究。
3.多吡啶配合物为基元的分子器件设计及其光电性能应用。[2]
学术成绩
1．已发表学术论文40多篇, 其中SCI收录论文30篇。  
2．现主持国家自然科学基金1项，参加国家、省自然科学基金及国家重点实验室开放课题基金5项。
(1) 国家自然科学基金项目（2002.1-2004.12）：钌多吡啶配合物为基元的某些分子器件设计及其应用，项目负责人。
(2) 国家自然科学基金项目（2001.1-2003.12）：金属配合物研究DNA的结构、功能及作用机制，主要成员。
(3) 国家自然科学基金重点项目（2003.1-2005.12）：金属配合物、生物大分子蛋白质和DNA的相互作用，主要成员。
(4) 广东省自然科学项目（2003.1-2005.12）：抗癌性多吡啶类配合物量子化学研究、计算机模拟及合成, 主要成员。
(5) 配位化学国家重点实验室（南京大学）开放课题基金（2002.4-2004.3）：位点和顺序专一RNA和DNA切割剂合成及其作用机制，主要成员。
(6) 生命有机化学国家重点实验室（中科院上海有机化学研究所）开放课题基金(2000.7-2003.6)：核酸的结构与功能关系中的重大化学问题的研究，主要成员。
教学科研成果
“金属酶模型化合物的结构、生物功能、作用机制之间规律性”，中国高校自然科学奖二等奖，2000年（排名第九）。
主要论著
（均为SCI收录）：
1. Feng Gao, Hui Chao*, Feng Zhou, Xin Chen, Yuan-Fang Wei, Kang-Cheng Zheng, Liang-Nian Ji*, “Synthesis, DNA binding and topoisomerase II inhibition activities of ruthenium(II) polypyridyl complex containing 11-aminopteridino[6,7-f][1,10]phenanthrolin-13(12H)-one”,J. Inorg. Biochem. ,2008, in press.
2. Feng Gao, Hui Chao*, Liang-Nian Ji*,“DNA-Binding, Photocleavge and Topoisomerase Inhibiting of Functionalized Ruthenium(II) Polypyridyl Complexes”,Chemistry & Biodiversity, 2008, in press. (Review)
3. Hui-Juan Yu, Hui Chao*, Long Jiang, Lv-Ying Li, Shu-Mei Huang and Liang-Nian Ji*, “Single oxygen-mediated DNA photocleavage of a di-bithiazolyl ruthenium(II) complex [Ru(btz)2(dppz)]2+”, Inorg. Chem. Commun. ,2008, in press.
4. Feng Gao, Hui Chao*, Yuan-Fang Wei, Yi-Xian Yuan, Bin Peng, Xin Chen, Kang-Cheng Zheng and Liang-Nian Ji*, “Synthesis, DNA-Binding and Photocleavage Studies of Ruthenium(II) Complexes [Ru(phen)2(ppd)]2+ and [Ru(phen)(ppd)2]2+ (ppd = Pteridino[6,7-f][1,10]- phenanthroline-1,13(10H,12H)-dione, phen = 1,10-Phenanthroline)”, Helv. Chim. Acta, 2008, in press.
5. F. Albert Cotton, Hui Chao*, Zhong Li, Carlos A. Murillo, Qingsheng Wang, “Effect of axial anthracene ligands on the luminescence of trinickel molecular wires”, J. Organomet. Chem., 2008, in press.
6.巢晖*，高峰，计亮年*，“钌(II)多吡啶配合物与DNA相互作用研究”，化学进展，2007，19(12)，1844-1851。 (化学生物学专辑，Review)
7. Feng Gao, Hui Chao*, Jin-Quan Wang, Yi-Xian Yuan, Bin Sun, Yuan-Fang Wei, Bin Peng and Liang-Nian Ji*, “Targeting topoisomerase II with the chiral DNA-intercalating ruthenium(II) polypyridyl complexes”,J. Biol. Inorg. Chem., 2007, 12, 1015-1027.
8. Bin Peng, Hui Chao*, Bin Sun, Hong Li, Feng Gao and Liang-Nian Ji*, “Syntheses, DNA-binding and photocleavage studies of cobalt(III) mixed-polypyridyl complexes: [Co(phen)2(dpta)]3+ and [Co(phen)2(amtp)]3+”, J. Inorg. Biochem. ,2007, 101, 404-411.
9. Feng Gao, Hui Chao*, Feng Zhou, Bin Peng, Liang-Nian Ji*, “pH responsive “off-on-off” luminescent switch of a novel ruthenium(II) complex [Ru(bpy)2(pipipH2)]2+”, Inorg. Chem. Commun., 2007, 10, 170-173.
10. Feng Gao, Hui Chao*, Feng Zhou, Lian-Cai Xu, Kang-Cheng Zheng, Liang-Nian Ji*,“Synthesis, Characterization, and DNA-Binding Properties of the Chiral Ruthenium(II) Complexes Δ- and Λ-[Ru(bpy)2(dmppd)]2+ (dmppd = 10,12-Dimethylpteridino- [6,7-f][1,10]phenanthroline-11,13(10H,12H)-dione; bpy = 2,2’-Bipyridine)”, Helv. Chim. Acta, 2007, 90, 36-51.
11. F. Albert Cotton, Hui Chao*, Carlos A. Murillo* and Qingsheng Wang, “A trimetal chain cocooned by two heptadentate polypyridylamide ligands”,Dalton Trans. ,2006, 5416-5422.
12. Feng Gao, Hui Chao*, Feng Zhou, Yi-Xian Yuan, Bin Peng and Liang-Nian Ji*, “DNA interactions of a functionalized ruthenium(II) mixed-polypyridyl complex [Ru(bpy)2ppd]2+”,J. Inorg. Biochem., 2006, 100, 1487-1494.
13. Yun-Jun Liu, Hui Chao*, Yi-Xian Yuan, Hui-Juan Yu and Liang-Nian Ji*,“Ruthenium(II) mixed-ligand complexes containing 2-(6-methyl-3-chromonyl)imidazo- [4,5-f][1,10]phenanthroline: synthesis, DNA-binding and photocleavage studies”,Inorg. Chim. Acta, 2006, 359, 3807-3814.
14. Hui Chao, Liang-Nian Ji, “Chapter 11. Cobalt complexes as potential pharmaceutical agents”, in Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine, Eds. Marcel Gielen and Edward R. T. Tiekink, May, 2005, John Wiley & Sons Ltd (ISBN: 0-470-86403-6). (Book Chapter)
15. Hui Chao*, Lian-Nian Ji, “DNA interactions with Ru(II) polypyridine complexes containing asymmetric ligands”, Bioinorganic Chemistry and Application, 2005, 3, 15-28.（Review）
16. Yun-Jun Liu, Hui Chao*, Jun-Hua Yao, Li-Feng Tan, Yi-Xian Yuan, Liang-Nian Ji, “Ruthenium(II) complexes containing asymmetric 2-(pyrazin-2-yl)naphthoimidazole: syntheses, characterization, DNA-binding and photocleavage studies”,Inorg. Chim. Acta, 2005, 358, 1904-1910.
17. Li-Feng Tan, Hui Chao*, Yun-Jun Liu, Hong Li, Bin Sun, Liang-Nian Ji*, “DNA-binding and photocleavage studies of [Ru(phen)2(NMIP)]2+”, Inorg. Chim. Acta, 2005, 358, 2191-2198.
18. Yun-Jun Liu, Hui Chao*, Li-Feng Tan, Yi-Xian Yuan, Wei Wei, Liang-Nian Ji*. “Interaction of polypyridyl ruthenium(II) complex containing asymmetric ligand with DNA”. J. Inorg. Biochem. ,2005, 99, 530-537.
19. Li-Feng Tan, Hui Chao*, Hong Li, Yun-Jun Liu, Bin Sun, Wei Wei, Liang-Nian Ji*. “Synthesis, characterization, DNA-binding and photocleavage studies of [Ru(bpy)2(PPIP)]2+ and [Ru(phen)2(PPIP)]2+”.J. Inorg. Biochem. ,2005, 99, 513-520.
20. Yun-Jun Liu, Hui Chao*, Jun-Hua Yao, Hong Li, Yi-Xian Yuan, Liang-Nian Ji*. “Synthesis, characterization and DNA interaction studies of [Ru(bpy)2(CMIP)]2+ and [Ru(phen)2(CMIP)]2+ (CMIP = 2-(3-chromonyl)imidazo[4,5-f][1,10]-phenanthroline)”. Helv. Chim. Acta, 2004, 87, 3119-3130.
21. Xiang-Li Wang, Hui Chao*, Hong Li, Xian-Lan Hong, Yun-Jun Liu, Li-Feng Tan, Liang-Nian Ji*. “DNA interactions of cobalt(III) mixed-polypyridyl complexes containing asymmetric ligands.” J. Inorg. Biochem. ,2004, 6, 1143-1150.
22. Xiang-Li Wang, Hui Chao*, Hong Li, Xian-Lan Hong, Liang-Nian Ji*, Xiao-Yuan Li*. “Synthesis, crystal structure and DNA cleavage activities of copper(II) complexes with asymmetric tridentate ligands.”, J. Inorg. Biochem. ,2004, 98, 423-429.
23. Xian-Lan Hong, Hui Chao*, Li-Jun Lin, Kang-Cheng Zheng*, Hong Li, Xiang-Li Wang, Feng-Cun Yun, Liang-Nian Ji*. “Synthesis, characterization and DNA-binding properties of complexes [Ru(dppt)(dipn)]2+ and [Ru(pta)(dipn)]2+.” Helv. Chim. Acta., 2004, 87, 1180-1193.
24. Xian-Lan Hong, Hui Chao*, Jun-Hua Yao, Hong Li, Liang-Nian Ji*. “Synthesis, characterization, electrochemistry and solvatochromic studies of [Ru(dppt)(dien)]2+ and [Ru(pta)(dien)]2+ ”. Polyhedron, 2004, 23, 815-821.
25. Hui Chao*, Zhi-Ren Qiu, Li-Rong Cai, Hao Zhang, Xiao-Yuan Li*, Kam-Sing Wong, Liang-Nian Ji*. “Mono-, di- and tetranuclear ruthenium(II) complexes containing 3-(pyridin-2-yl)-as-triazino[5,6-f]1,10-phenanthroline: synthesis, characterization, electrochemical and photophysical properties.” Inorg. Chem., 2003, 42, 8823-8830.
26. Cai-Wu Jiang, Hui Chao*, Hong Li, Liang-Nian Ji*, “Syntheses, Characterization and DNA-binding Studies of Ruthenium(II) Terpyridine Complexes: [Ru(tpy)(PHBI)]2+ and [Ru(tpy)(PHNI)]2+.” J. Inorg. Biochem., 2003, 93, 247-255.
27. Cai-Wu Jiang, Hui Chao*, Xian-Lan Hong, Hong Li, Wen-Jie Mei, Liang-Nian Ji*, “Enantiopreferential DNA-
28. Hui Chao*, Wen-Jie Mei, Qi-Wen Huang, Liang-Nian Ji*, “DNA Binding Studies of Ruthenium(II) Complexes Containing Asymmetric Tridentate Ligands.” J. Inorg. Biochem.,2002, 92, 165-170