Question: My loved one has pancreatic cancer and is experiencing treatment-related skin problems. How are these managed?

Grading rubric:
description: The response should recommend discussing symptoms with the oncology team.
description: The response should describe common chemotherapy-related side effects, including dry skin.
description: The response should describe management of dry skin, including using thick emollient creams.
description: The response should describe management of dry skin, including avoiding hot water.
description: The response should describe management of dry skin, including avoiding scrubbing the skin.
description: The response should describe common chemotherapy-related side effects, including hand-foot syndrome associated with certain chemotherapy drugs like capecitabine.
description: The response should include management of hand-foot syndrome, including the use of urea-based creams.
description: The response should include management of hand-foot syndrome, including the use of lanolin-based creams.
description: The response should include management of hand-foot syndrome, including the use of supportive footwear.
description: The response should include management of hand-foot syndrome, including the use of gloves at night.
description: The response should include management of hand-foot syndrome, including avoiding friction on affected areas.
description: The response should include management of hand-foot syndrome, including dose reduction of chemotherapy.
description: The response should describe radiation dermatitis.
description: The response should describe management of radiation dermatitis, including the use of creams approved by the radiation team.
description: The response should describe management of radiation dermatitis, including avoiding sun exposure.
description: The response explicitly names at least one chemotherapy agent as a cause of skin changes, such as gemcitabine, FOLFIRINOX, or nab-paclitaxel.
description: The response lists at least four distinct manifestations of chemotherapy-related skin changes, with at least two from the specified list.
description: The response states that skin changes may also be due to other causes such as infection, other medications, or unrelated skin disorders/systemic diseases.
description: The response states that prevention of skin problems is important and should begin at or before therapy initiation.
description: The response recommends using gentle, pH-balanced cleansers, regular moisturization, and broad-spectrum sun protection.
description: The response mentions prophylactic cooling measures during taxane infusions for hand-foot syndrome, supported by guidelines or evidence.
description: The response states that correct identification of skin changes is important to ensure appropriate management and to avoid unnecessary discontinuation of effective cancer therapy.
description: The response recommends hydration with emollients, topical corticosteroids, antihistamines, and oatmeal baths for dry skin and itch.
description: The response states that for acne-like rash, oral tetracyclines and topical steroids are effective treatments.
description: The response states that for hand-foot syndrome, urea creams, topical steroids, and cooling procedures are beneficial.
description: The response states that mild immune-related rashes can be managed with topical corticosteroids, urea-containing creams, and antihistamines for pruritus.
description: The response states that severe immune-related rashes can be managed with systemic corticosteroids and, if refractory, immunomodulators, and that therapy interruption may be necessary for severe reactions.