Tricyclic antidepressant

Table columns:
Compound
SERT
NET
DAT
5-HT1A
5-HT2A
5-HT2C
5-HT6
5-HT7
α1
α2
D2
H1
H2
mACh
σ1
σ2

Table rows:
cells: Amineptine
>100,000
10,000
1,000–1,400
>100,000
74,000
ND
ND
ND
>100,000
>100,000
>100,000
≥13,000
ND
>100,000
ND
ND
cells: Amitriptyline
2.8–4.3
19–35
3,250
≥450
18–23
4.0
65–141
93–123
4.4–24
114–690
196–1,460
0.5–1.1
66
9.6
300
ND
cells: Amoxapine
58
16
4,310
ND
0.5
2.0
6.0–50
41
50
2,600
3.6–160
7.9–25
ND
1,000
ND
ND
cells: Butriptyline
≥1,360
5,100
3,940
7,000
380
ND
ND
ND
570
4,800
ND
1.1
ND
35
ND
ND
cells: Clomipramine
0.14–0.28
38–54
≥2,190
≥7,000
27–36
65
54
127
3.2–38
≥535
78–190
13–31
209
37
546
ND
cells: Desipramine
18–163
0.63–3.5
3,190
≥6,400
115–350
244–748
ND
>1,000
23–130
≥1,379
3,400
60–110
1,550
66–198
≥1,990
≥1,610
cells: Dibenzepin
ND
ND
>10,000
>10,000
≥1,500
ND
ND
ND
>10,000
>10,000
>10,000
23
1,950
1,750
ND
ND
cells: Dosulepin
8.6–78
46–70
5,310
4,000
152
ND
ND
ND
419
2,400
ND
3.6–4.0
ND
25–26
ND
ND
cells: Doxepin
68–210
13–58
≥4,600
276
11–27
8.8–200
136
ND
24
28–1,270
360
0.09–1.23
174
23–80
ND
ND
cells: Imipramine
1.3–1.4
20–37
8,500
≥5,800
80–150
120
190–209
>1,000
32
3,100
620–726
7.6–37
550
46
332–520
327–2,100
cells: Iprindole
≥1,620
1,260
6,530
2,800
217–280
206
ND
ND
2,300
8,600
6,300
100–130
200–8,300
2,100
>10,000
ND
cells: Lofepramine
70
5.4
>10,000
4,600
200
ND
ND
ND
100
2,700
2,000
245–360
4,270
67
2,520
ND
cells: Maprotiline
5,800
11–12
1,000
ND
51
122
ND
50
90
9,400
350–665
0.79–2.0
776
570
ND
ND
cells: Norclomipramine
40
0.45
2,100
19,000
130
ND
ND
ND
190
1,800
1,200
450
ND
92
ND
ND
cells: Northiaden
192
25
2,539
2,623
141
ND
ND
ND
950
ND
ND
25
ND
110
ND
ND
cells: Nortriptyline
15–18
1.8–4.4
1,140
294
5.0–41
8.5
148
ND
55
2,030
2,570
3.0–15
646
37
2,000
ND
cells: Opipramol
≥2,200
≥700
≥3,000
>10,000
120
ND
ND
ND
200
6,100
120–300
6.0
4,470
3,300
0.2–50
110
cells: Protriptyline
19.6
1.41
2,100
3,800
70
ND
ND
ND
130
6,600
2,300
7.2–25
398
25
ND
ND
cells: Tianeptine
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
>10,000
cells: Trimipramine
149–2,110
≥2,450
≥3,780
8,000
32
537
ND
ND
24
680
143–210
0.27–1.5
41
58
ND
ND
cells: Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site. For assay species and references, see the individual drug articles. Most but not all values are for human proteins.

Questions about this table:
originalText: what is an example of a tricyclic antidepressant
answer: answerTexts: Amineptine