Task: Class Relation Understanding (ontology: Sciences/Biology)

Which of the following classes is one valid superclass of 'negative regulation of transcription initiation by RNA polymerase II'?

A. 2-dehydro-3-deoxy-D-gluconate aldolase activity
B. 4-hydroxy-2-oxovalerate aldolase activity
C. negative regulation of DNA-templated transcription initiation
D. 3'(2'),5'-bisphosphate nucleotidase activity

Answer: negative regulation of DNA-templated transcription initiation