Task: Class Definition Understanding (ontology: Sciences/Biology)

Which of the following definitions best describes '49,XXXXX syndrome'?

A. A rare sex chromosome abnormality in which a female child has 3 extra X chromosomes.
B. A rare Y chromosome number anomaly that affects only males. The disease has characteristics of mild-moderate developmental delay (especially speech), normal to mild intellectual disability, large, irregular teeth with poor enamel, tall stature and acne. Radioulnar stenosis and clinodactyly have also been associated. Boys generally present normal genitalia, while hypogonadism and infertility is frequently reported in adult males.
C. A type of hypogonadism in a person whose karyotype is 46,XY. People with the concept are born with the appearance of a normal female in most anatomic respects except that the child has nonfunctional streak gonads instead of ovaries or testes. As their ovaries produce no important body changes before puberty, a defect of the reproductive system typically remains unsuspected until puberty fails to occur. They appear to be normal women and are generally considered so.
D. A gonadal dysgenesis syndrome characterized by the absence of a part or all of one of the sex chromosomes. Signs and symptoms include short stature, webbing of neck, low-set ears, hypogonadism, and sterility.

Answer: A rare sex chromosome abnormality in which a female child has 3 extra X chromosomes.