Task: Class Definition Understanding (ontology: Sciences/Biology)

Which of the following definitions best describes 'Brodmann (1909) area 16'?

A. the concept, or the concept, is part of the frontal cortex in the human brain. It is between BA10 and BA45. the concept is known as the concept. In the human it occupies approximately the middle third of the middle frontal gyrus and the most rostral portion of the inferior frontal gyrus. the concept roughly corresponds with the dorsolateral prefrontal cortex (DLPFC), although the borders of the concept are based on cytoarchitecture rather than function. The DLPFC also encompasses part of granular frontal area 9, directly adjacent on the dorsal surface of the cortex. Cytoarchitecturally, the concept is bounded dorsally by the granular frontal area 9, rostroventrally by the frontopolar area 10 and caudally by the triangular area 45 (Brodmann-1909). There is some discrepancy between the extent of BA8 (Brodmann-1905) and the same area as described by Walker (1940).
B. the concept, also the concept or the concept, is part of the temporal cortex in the human brain. BA 38 is at the the concept, known as the the concept. the concept is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. It is located primarily in the most rostral portions of the superior temporal gyrus and the middle temporal gyrus. Cytoarchitecturally it is bounded caudally by the inferior temporal area 20, the middle temporal area 21, the superior temporal area 22 and the ectorhinal area 36 (Brodmann-1909). Cytoarchitectonic and chemoarchitectonic studies find that it contains at least seven subareas, one of which, TG, is unique to humans. 'The functional significance of this area TG is not known, but it may bind complex, highly processed perceptual inputs to visceral emotional responses.' This area is among the earliest affected by Alzheimer's disease and the earliest involved at the start of temporal lobe seizures.
C. The the concept, also known in the human brain as the dorsal anterior cingulate area 32, refers to a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. In the human it forms an outer arc around the anterior cingulate gyrus. The cingulate sulcus defines approximately its inner boundary and the superior rostral sulcus (H) its ventral boundary; rostrally it extends almost to the margin of the frontal lobe. Cytoarchitecturally it is bounded internally by the ventral anterior cingulate area 24, externally by medial margins of the agranular frontal area 6, intermediate frontal area 8, granular frontal area 9, frontopolar area 10, and prefrontal area 11-1909. (Brodmann19-09). Dorsal region of anterior cingulate gyrus is associated with rational thought processes, most notably active during the Stroop task.
D. the concept is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It is a relatively undifferentiated cortical area that Brodmann regarded as part of the insula because of the relation of its innermost multiform layer (VI) with the claustrum (VICl). The laminar organization of cortex is almost totally lacking. The molecular layer (I) is wide as in area 15 of Brodmann-1905. The space between layer I and layer VI is composed of a mixture of pyramidal cells and spindle cells with no significant number of granule cells. Pyramidal cells clump in the outer part to form glomeruli similar to those seen in some of the primary olfactory areas (Brodmann-1905). This term also refers to an area known as peripaleocortical claustral - a cytoarchitecturally defined (agranular) portion of the insula at its rostral extreme where it approaches most closely the claustrum and the prepyriform area (Stephan-76).

Answer: the concept is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It is a relatively undifferentiated cortical area that Brodmann regarded as part of the insula because of the relation of its innermost multiform layer (VI) with the claustrum (VICl). The laminar organization of cortex is almost totally lacking. The molecular layer (I) is wide as in area 15 of Brodmann-1905. The space between layer I and layer VI is composed of a mixture of pyramidal cells and spindle cells with no significant number of granule cells. Pyramidal cells clump in the outer part to form glomeruli similar to those seen in some of the primary olfactory areas (Brodmann-1905). This term also refers to an area known as peripaleocortical claustral - a cytoarchitecturally defined (agranular) portion of the insula at its rostral extreme where it approaches most closely the claustrum and the prepyriform area (Stephan-76).