for the for the patient and this goes back to stress they show very poor um resilience in the face of even moderate stressors and you can imagine being surrounded by a family living there and they're constantly getting upset and you know like i i think it's like very obvious that this is something that would happen yeah um yeah just causing that split i think the brain just wants to flee and and the other thing is um regarding cultural differences this doesn't seem to be the case if you look at less industrialized countries um more industrialized countries tend to have uh high rates of emotional expression in families and less industrialized countries tend to have better rates of remission better outcomes for patients with schizophrenia and they think it's largely linked to the fact that these families tend to interact in less hostile and critical ways yeah no that's really interesting yeah yeah so i mean you know artie lang wasn't you know entirely wrong um and his criticism of uh the way psychiatry was treating the illness at the time was i think valid um because it was very reductive um and i think just regarding causality and schizophrenia it is insanely complicated and there's like a million different factors and i think it speaks to the fragility of our uh consciousness and our minds and just any one little thing can offset this incredibly uh brilliant system and it could end in like the an utter collapse in our ability to interact with reality um i'm just gonna ask a question about uh something i've been thinking about um revolving schizophrenia and psychosis um because i remember i did some research on it was meditation sleeping psychedelic use trances um and like kind of uh spiritual psychosis i guess and then schizophrenia and psychotic-like disorders and what i found is that with sleeping right before you fall asleep and when you're dreaming the default mode network part of the brain is almost disabled in psychedelics which some people have said is like a psychotic-like state the default mode network is also disabled same with meditation and deep like in deep meditation with psychosis and schizophrenia however the default mode network instead of being off is actually overactive so because there's such kind of similar states at least in my opinion all all of those examples why do you think that schizophrenia and psychosis specifically has such a different reaction in the brain um i mean regarding like the the anatomical reason why is that the uh schizophrenic patients show uh reduced white matter volume um in their brain and white matter is like you can think of it as like uh you know cables have like the i don't know plastic or rubber around them that kind of insulates them and it also makes them uh you know move move the electrical signal signals more quickly um in the same way yeah sort of like uh the myelin sheath that goes around our neurons it like insulates them and it like helps the signals go faster and it kind of nourishes them and everything so to have reduced white matter is bad because that means you're gonna have problems with uh connectivity and um this is uh you know we're gonna see specifically with the default mode network the disassociation pattern of functional connectivity of the subsystems in the default mode network um and that's the kind of anatomical reason so i mean broadly people
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