of course dr octopus at the beginning of the amazing spider-man annual one we see doctor octopus escaping from prison mentally controlling his mechanical arms to break him out once free from prison octavius calls a meeting with some of the deadliest spider-man villains such as craven hunter mysterio and electro they're also waiting for vulture and sandman anyway craven ultimately says octavius has a great idea each of us almost defeated spider-man alone together how could we fail once vulture and sandman show up octavia says great now we can start here's the plan we learned that the plan is to have each villain fight spider-man at a specific place that will give them the upper hand and after each fight spider-man will become weaker and weaker until ultimately one of them takes him down we actually go over this in great detail in our origin of the sinister six episode so if you want to know more about how the first confrontation with the sinister six went down check out that video right here sometime after this in the amazing spider-man issues NUMBER_TOKEN-NUMBER_TOKEN we got the doc ock win story basically doctor octopus goes after spider-man once again trying to kill spidey once and for all but this time he has his ultimate plan and zaps spider-man with the nullifier not to be confused with the ultimate nullifier something completely different once hit with this device spider-man loses his memory octavius realizes he can use this to his advantage and is able to convince spider-man that the two are actually partners basically octavius comes to the conclusion that spider-man on his side working with him is more valuable to him than just killing the web head but like most evil geniuses doc ock's arrogance and overconfidence ultimately cost him the win meaning spider-man would come too and defeat octavius leaving him arrested while spider-man got away after this we have the death shall come storyline which took place in the amazing spider-man issues NUMBER_TOKEN through NUMBER_TOKEN. now this is a storyline i had to mention because in it dr octopus becomes the catalyst for the death of george stacy and the irony is it was an accident but nonetheless it happened because of doc ock you see doctor octopus accidentally smashed a chimney on top of a building and the debris started coming down and was about to land on top of a small child but george stacy pushed himself out of the way sacrificing himself point is if green goblin is responsible for gwen stacy's death doctor octopus is responsible for her father george stacy's death accident or not moving along we have another great story arc called the web of death in this story spider-man is basically down and out and suffering from a deadly poison he's also having really bad emotional traumas and basically is just in a bad state both physically and mentally and when dr octopus finds out about this he doesn't try to kick spider-man when he's down no he actually tries to help spider-man it's a story that shows the other side of doctor octopus and a deeper
START_SELFPROMO_TOKEN actually go over this in great detail in our origin of the sinister six episode so if you want to know more about how the first confrontation with the sinister six went down check out that video right here END_SELFPROMO_TOKEN