Molecule ID: 3657

IUPAC Name: hydroxyurea

Description: The molecule is a member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. It has a role as a DNA synthesis inhibitor, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an antineoplastic agent, a genotoxin, an antimetabolite, a teratogenic agent, a radical scavenger, an immunomodulator and an antimitotic. It is a member of ureas and a one-carbon compound.

SMILES: N=C(O)NO

SELFIES: [N][=C][Branch1][C][O][N][O]

InChI: InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)

Molecular Properties:
- Polar Surface Area: 75.4 Ų
- LogP: -1.8