Molecule ID: 1884

IUPAC Name: 7-chloro-4-oxo-1H-quinoline-2-carboxylic acid

Description: The molecule is a quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid. It has a role as a neuroprotective agent and a NMDA receptor antagonist. It is an organochlorine compound and a quinolinemonocarboxylic acid.

SMILES: O=C(O)c1cc(=O)c2ccc(Cl)cc2[nH]1

SELFIES: [O][=C][Branch1][C][O][C][=C][C][=Branch1][C][=O][C][=C][C][=C][Branch1][C][Cl][C][=C][Ring1][#Branch1][NH1][Ring1][N]

InChI: InChI=1S/C10H6ClNO3/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13/h1-4H,(H,12,13)(H,14,15)

Molecular Properties:
- Polar Surface Area: 66.4 Ų
- LogP: 1.9