VictorJuiz/thesis huggingface dataset:
Novelty detection with extreme value theory in vital-sign monitoring

Every year in the UK, tens of thousands of hospital patients suffer adverse events, such as un- planned transfers to Intensive Therapy Units or unexpected cardiac arrests. Studies have shown that in a large majority of cases, significant physiological abnormalities can be observed within the 24-hour period preceding such events. Such warning signs may go unnoticed, if they occur between observations by the nursing staff, or are simply not identified as such. Timely detection of these warning signs and appropriate escalation schemes have been shown to improve both patient outcomes and the use of hospital resources, most notably by reducing patients’ length of stay.
Automated real-time early-warning systems appear to be cost-efficient answers to the need for continuous vital-sign monitoring. Traditionally, a limitation of such systems has been their sensitivity to noisy and artefactual measurements, resulting in false-alert rates that made them unusable in practice, or earned them the mistrust of clinical staff. Tarassenko et al. (2005) and Hann (2008) proposed a novelty detection approach to the problem of continuous vital- sign monitoring, which, in a clinical trial, was shown to yield clinically acceptable false alert rates. In this approach, an observation is compared to a data fusion model, and its “normality” assessed by comparing a chosen statistic to a pre-set threshold. The method, while informed by large amounts of training data, has a number of heuristic aspects.
This thesis proposes a principled approach to multivariate novelty detection in stochastic time- series, where novelty scores have a probabilistic interpretation, and are explicitly linked to the starting assumptions made. Our approach stems from the observation that novelty detection using complex multivariate, multimodal generative models is generally an ill-defined problem when attempted in the data space. In situations where “novel” is equivalent to “improbable with respect to a probability distribution ”, formulating the problem in a univariate probability space allows us to use classical results of univariate statistical theory. Specifically, we propose a multivariate extension to extreme value theory and, more generally, order statistics, suitable for performing novelty detection in time-series generated from a multivariate, possibly multimodal model.
All the methods introduced in this thesis are applied to a vital-sign monitoring problem and compared to the existing method of choice. We show that it is possible to outperform the existing method while retaining a probabilistic interpretation.
In addition to their application to novelty detection for vital-sign monitoring, contributions in this thesis to existing extreme value theory and order statistics are also valid in the broader context of data-modelling, and may be useful for analysing data from other complex systems.

Keywords: order statistics
novelty detection
extreme value theory
patient monitoring
Advisor: Tarassenko, L
Clifton, D
A study in Augustine and Calvin of the Church regarded as the number of the elect and as the body of the baptized

Preface.
For the greater part of the history of the Christian Church the doctrines of baptism and predestination have been uneasy bed-fellows. At times, the former has gained the predominance and the latter has been relegated to the region of philosophical prolegomena to faith, having no immediate connection with the Christian life. In other periods, the doctrine of predestination has gained the ascendency and the importance of baptism has been minimized. Nevertheless, both these aspects of the Christian faith are strikingly present in the New Testament, and in no way do we find there premonitions of the tensions between them in the later history of the Church. Is this because of the unsystematic nature of the New Testament faith which evaded these difficulties through its own lack of order, or is there a deeper reason for the primitive harmony between these two aspects of Christian theology?
[contined in text ...]
Hominin dispersals and the middle palaeolithic of Arabia

This thesis tests models on the dispersal of hominin populations in the Upper Pleistocene, specifically in relation to the Arabian Peninsula. It does so by conducting a quantified comparison of lithic assemblages from northeast Africa and southwest Asia. Lithic data from new excavations at the Jubbah Palaeolake in northern Saudi Arabia is compared to assemblages from Ethiopia, Sudan, Egypt, Jordan, Iran, Oman and other localities in Saudi Arabia. This is the first detailed inter-regional study of this area for Marine Isotope Stages 5 to 3, a critical spatial and temporal context in debates on both early modern human and Neanderthal demography and dispersal. The spatial and temporal character of the rich Arabian archaeological record correlate with emerging evidence for environmental change in Arabia; in particular the repeated dating of archaeological contexts to periods of climatic amelioration suggests that demographic growth was associated with periods of increased precipitation. The various factors influencing lithic variability and the methodologies by which they can be elucidated are reviewed. In particular this highlights the need for quantified and comparative analyses. A variety of analytical approaches are applied in this thesis, including the use of Correspondence and Principal Components Analyses to develop a nuanced view of lithic variability. Variability in cores is shown to largely reflect the related factors of size and reduction intensity. With analyses of debitage and retouched lithics a broadly similar picture emerges: assemblages which are heavily reduced have small cores and blanks and higher levels of retouch, and elements of shape variation also change in relation to reduction intensity. Elements of residual variability may reflect cultural differences. While it is felt that the evidence presented broadly orientates the Upper Pleistocene Middle Palaeolithic of Arabia to dispersals from Africa, this suggestion is subsumed with a problematization of using lithic evidence to understand dispersals. Aside from the need for further dated archaeological material from Arabia and surrounding countries, lithic analyses need to more thoroughly consider factors such as reduction intensity if we are to make robust inferences on population dispersals.

Keywords: middle palaeolithic
hominin
archaeology
dispersal
lithics
Advisor: Petraglia, M
Dark energy and the inhomogeneous universe

In this thesis, I study the relativistic effects of matter inhomogeneities on the accelerating expansion of the Universe. The acceleration is often taken to be caused by the presence of an exotic fluid called Dark Energy, or else a non-zero 'cosmological constant' term in the field equations of General Relativity. I consider whether this result could instead be an artefact caused by using an incorrect model to interpret observations. The standard 'concordance' cosmological model assumes the Cosmological Principle, which states that the matter distribution on large scales is homogeneous. One possibility is that correction terms appear in the field equations when small-scale inhomogeneities are smoothed over to produce this homogeneous model. These 'backreaction' effects could affect the dynamics of the spacetime, causing an apparent acceleration. I clarify the relationship between acceleration of the averaged spacetime and acceleration inferred from observable quantities, and show that they are closely related in statistically-homogeneous spacetimes.
Another possibility is that the Universe could be inhomogeneous on large scales. If there was a large ‘void’, with us at the centre, the lensing of light by the void could reproduce the observations that imply cosmic acceleration. I show that a popular class of void models, based on spherically-symmetric Lemaitre-Tolman-Bondi spacetimes, are unable to simultaneously fit a selection of observational data, thus effectively ruling-out this possibility. These data include the Kinematic Sunyaev-Zel'dovich (KSZ) effect, which is a distortion/shift of the Cosmic Microwave Background (CMB) frequency spectrum caused by the Compton scattering of photons by hot gas in galaxy clusters. This, and other distortions of the CMB frequency spectrum, are sensitive to the degree of anisotropy in the CMB about a scattering cluster. I suggest tests involving these observables that exploit the strong link between isotropy and homogeneity to (a) distinguish between different causes of a deviation from spatial flatness on the horizon scale, and (b) potentially confirm the Cosmological Principle using observations. Finally, I describe a novel Bayesian CMB component separation method for extracting the Sunyaev-Zel'dovich signal of clusters from CMB sky maps.

Keywords: Sunyaev-Zel'dovich effect
dark energy
inhomogeneous cosmology
cosmology
cosmic microwave background
Gibbs sampling
Advisor: Ferreira, P
Clifton, T
The sources of economic growth in the New Zealand economy after 1950

This thesis investigates some aspects of the ordering of nuclear spin systems at low temperatures. The thesis is divided into two parts.
In part one some nuclear orientation experiments of 74As in Fe and 206Bi and Ni and Fe are described. These nuclei are orientated by the large hyperfine field inside Ni and Fe. The orientation is detected by the anisotropy of the emitted gamma-rays and in the case of 74As by the destruction of this anisotropy by NMR. Chapter one reviews the theory of the nuclear orientation method. To aid in the interpretation of the 206Bi results, some channelling experiments were done. A review of the method of atom location by channelling is given in chapter two. Chapter three describes the apparatus and technique used. The results of the 74AsFe experiments are given in chapter four. In these experiments the magnetic moment of the ground state of 74As was measured to be μ = 1.597(3), the sign of the hyperfine field was found to be positive, and the spin-lattice relaxation time was found to be 120(30) s.
The results of the 206BiNi experiments are given in chapter five. The hyperfine was found to be 390(15) kOe for both diffused polycrystalline and implanted single crystal samples. The multipolarity mixing ratios of many of the gamma,-rays were found. Reorientation of the metastable state of 206Pb was observed, which had not been expected. On the basis of the channelling experiments, this reorientation has been explained by the theory

Advisor: Corden, W
The power of legitimacy: local cooperation and the effectiveness of peace operations

This thesis investigates how peace operations work. It contributes to the larger study of peace operation effectiveness by analysing the processes through which these institutions influence local actors in postconflict societies. Looking beyond traditional concerns with mandates and resources, it aims to understand how a peace operation seeks to achieve its goals, focusing on why local populations might cooperate with or obstruct its activities.
The thesis draws on theories of social power, compliance and legitimation to answer four central questions: what power do peace operations have to achieve their objectives? From where do peace operations derive power? How do local perceptions of an operation enable or constrain its effectiveness? How are peace operations legitimised at the local level, and with what effect?
It begins by critically reviewing the academic literature, arguing that existing approaches are unable to account for important dimensions of peace operation effectiveness because they neglect the local setting in which operations pursue their goals, and the extent to which the achievement of those goals requires local cooperation. It then develops an analytical framework to examine the processes of coercion, inducement and legitimacy through which peace operations seek to shape the decisions and actions of local actors.
This power-legitimacy framework is applied to study the effectiveness of the United Nations Transitional Authority in Cambodia (UNTAC) and the Regional Assistance Mission in Solomon Islands (RAMSI). By comparing variation in local cooperation between and within these cases, the thesis shows that the way a peace operation is locally perceived is an important but often overlooked determinant of its effectiveness. In particular, when local actors perceive a peace operation to be legitimate, they are more likely to behave in ways that assist the operation to achieve its goals. The thesis concludes by discussing the implications of this finding for the future study and practice of peace operations.

Keywords: Cambodia
Solomon Islands
peacekeeping
legitimacy
peace operations
power
Advisor: Foot, R
Prantl, J
Satire in the Old Testament

In recent years, through the process of narrative and literary criticism, scholars have begun suggesting that satire is present in specific texts of the Old Testament. Thus the primary function of this thesis is to analyse the validity of these arguments alongside suggesting different places where satire may be found. To achieve this goal, the thesis begins by analysing and defining satire as a concept. A clear definition provides the thesis with the method needed to identify satire in texts which predate any defined understanding of the concept. The thesis also uses satirical works from throughout history as templates for understanding similar types of satire within the biblical works.
Once this methodology has been established, different genres of the Old Testament form the different chapters of the thesis. It identifies four different places where satire is deployed. Thus it examines satire in narratives, the book of Jonah, prophetic texts and wisdom literature. Each chapter combines new ideas with the analysis of previous scholastic arguments concerning the presence of satire. Within each genre a different type of satire with a range of complexity is deployed. The idol critiques in prophetic texts show simplistic satire. Narrative satire shows both situational and character-based satire. The book of Jonah is an example of hypocritical satire. Finally, satire in the wisdom literature contains a range of different satirical styles.
The thesis concludes that satire is present within the texts of the Old Testament. This has implication to the field of satire. It affirms the existence of pre-Hellenistic satire. Alongside this, it shows that satire is a subconscious human technique, deployable even when the proponent has no defined understanding of the concept. In the field of Old Testament studies it provides an alternative reading of many familiar texts. A satirical reading provides clear insight into authorial intent as well as offering different interpretations of the texts which are examined.

Keywords: Parody
Old Testment
Literary studies
Comic
Satire
Advisor: Day, J
The verse of Lady Mary Wortley Montagu

Lady Mary Wortley Montagu, now known chiefly for her letters, was in her own day famous as a minor poet. This thesis discusses her verse in various genres, relating it to the conventions within which it was written and to the writer's particular interests and aims. It prints the text of all known verse by, or probably by, Lady Mary, with full textual apparatus and explanatory notes. As far as possible all manuscript and printed sources have been collated, their variants recorded, the poems dated, their origins explained, and parallels in other writers listed.
The exercise of authority in early Christianity from about 170 to about 270

This study examines the changing patterns of authority both within and between the local Christian communities at the end of the second century and during the third. Amid the general tightening of Church discipline, the most significant development is the expansion and consolidation of a "monarchical" episcopate rather than the monepiseopate. A monarchical bishop is distinguished from one of the latter type by a greater control over the local congregation, a universal acceptance within his community of his position as chief teacher, having the last word on questions of orthodoxy, and the ability to act without the approval of his clergy and laity.
The activities and writings of the chief Christian writers during the period under review are considered separately, and there is a section devoted to the relationships between the local Churches.
The period commences as the Church begins to emerge from the crisis tfce variegated and largely heretical movement called Gnosticism inflicted upon her. Among the Gnostics, only the Valentinians and the Marcionites formed Churches, as the remainder were gathered (around their teachers) in little groups, usually compared to the philosophical schools, tut also having some similarities with the mystery religion groupings. The general aim was the acquisition of saving knowledge, and the movement was generally characterised by rigid internal divisions, a passionate subjectivity and objection to community discipline, and a belief in secret traditions. Eventually the orthodox communities rejected this entire authority pattern, although the process took longer in Alexandria, where a more refined philosophical Gnosticism exerted considerable influence on Clement, and to some extent on Origen. The organization of the Marcionites was roughly the same as that in the orthodox community at Rome around the middle of the second century, and was quickly bypassed and rejected.
[Please see pdf. for full abstract.]
Reduced dimensionality quantum dynamics of chemical reactions

In this thesis a reduced dimensionality quantum scattering model is applied to the study of polyatomic reactions of type X + CH4 <--> XH + CH3.
Two dimensional quantum scattering of the symmetric hydrogen exchange reaction CH3+CH4 <--> CH4+CH3 is performed on an 18-parameter double-Morse analytical function derived from ab initio calculations at the CCSD(T)/cc-pVTZ//MP2/cc-pVTZ level of theory. Spectator mode motion is approximately treated via inclusion of curvilinear or rectilinear projected zero-point energies in the potential surface. The close-coupled equations are solved using R-matrix propagation. The state-to-state probabilities and integral and differential cross sections show the reaction to be primarily vibrationally adiabatic and backwards scattered. Quantum properties such as heavy-light-heavy oscillating reactivity and resonance features significantly influence the reaction dynamics. Deuterium substitution at the primary site is the dominant kinetic isotope effect. Thermal rate constants are in excellent agreement with experiment.
The method is also applied to the study of electronically nonadiabatic transitions in the CH3 + HCl <--> CH4 + Cl(2PJ) reaction. Electrovibrational basis sets are used to construct the close-coupled equations, which are solved via Rmatrix propagation using a system of three potential energy surfaces coupled by spin-orbit interaction. Ground and excited electronic surfaces are developed using a 29-parameter double-Morse function with ab initio data at the CCSD(T)/ccpV( Q+d)Z-dk//MP2/cc-pV(T+d)Z-dk level of theory, and with basis set extrapolated data, both corrected via curvilinear projected spectator zero-point energies. Coupling surfaces are developed by fitting MCSCF/cc-pV(T+d)Z-dk ab initio spin orbit constants to 8-parameter functions. Scattering calculations are performed for the ground adiabatic and coupled surface models, and reaction probabilities, thermal rate constants and integral and differential cross sections are presented. Thermal rate constants on the basis set extrapolated surface are in excellent agreement with experiment. Characterisation of electronically nonadiabatic nonreactive and reactive transitions indicate the close correlation between vibrational excitation and nonadiabatic transition. A model for comparing the nonadiabatic cross section branching ratio to experiment is discussed.

Keywords: vibrational states
vibronic states
thermal rate constants
potential energy surfaces
reaction rate constants
reaction dynamics
spin-orbit coupling
quantum scattering
spin-orbit interactions
Morse potential
ab initio calculations
Advisor: Clary, D
Networks of imperial tropical medicine: ideas and practices of health and hygiene in the British Empire, 1895-1914

This thesis investigates several previously neglected networks of imperial tropical medicine (ITM) in Britain and its tropical colonies at the turn of the twentieth-century. It argues for the need to bring back the ‘imperial’ to the study of medicine in colonial localities; and, in doing so, redefines the ‘imperial’ in relation to tropical medicine during this period. To accomplish this, the first part of the thesis considers largely ignored popular networks of ITM, including the 1900 London Livingstone Exhibition; guidebooks and manuals for tropical travel, health and hygiene; and commodities such as Burroughs Wellcome & Co.’s (BWC) Tabloid brand medicine chests and tropical clothing. The second part of the thesis investigates important, but under researched professional networks of ITM, including the training and experiences of non-medical missionaries educated at Livingstone College, London and the London Missionary School of Medicine (LMSM); and the formation and reform of the West African Medical Staff (WAMS).
All of the popular and professional networks discussed in this thesis were, for the most part, a response to the urgency generated by domestic and international high politics to ‘improve’ and ‘develop’ Britain’s tropical possessions. While representing a diversity of individuals and interests, one concern that they all shared was the supposed need to preserve Anglo-Saxon health in tropical climates. Such a disparate set of ‘agents of empire’, connected through a common interest, led to a complex set of ideas and practices of ITM, which were informed as much by the environment and climate, as new disciplines such as parasitology. This thesis also demonstrates that a significant fissure existed — within and outside the imperial state — between ideas of ITM and their practice. Ideas of ITM were often aggressively imperial in rhetoric but in practice they generally were not. Therefore, at the start of the twentieth-century ITM was not always working — directly — as a ‘tool of empire’. Nonetheless, this thesis demonstrates that the ‘imperial’ is still the most useful analytical category and organising principle for understanding Western medicine’s relationship to Britain’s tropical possessions during this period. By focusing on both the colony and the metropole, and the uneven power relationship that existed between them, it demonstrates that ideas and practices of medicine and hygiene intended for Britain’s tropical empire were neither colonial nor metropolitan, but imperial.

Keywords: British Empire
imperial medicine
imperialism
Advisor: Harrison, M