VictorJuiz/thesis huggingface dataset:
"Wounded harts": metaphor and desire in the epic-romances of Tasso, Sidney, and Spenser

If we consider the representation of the body in the epic-romances of Torquato Tasso, Philip Sidney, and Edmund Spenser, certain instances of wounding and laceration emerge as crucial turning points in the development of their respective narratives: Clorinda’s redemptive mutilation, Parthenia’s blood-drenched pallor, Amavia’s disquieting suicide, Venus’s insatiable orifice, Amoret’s “perfect hole.” This thesis affords a detailed comparative study of such passages, contending that the wound assumed a critical metaphoric dimension in sixteenth-century epic-romance literature, particularly in relation to the perceived association between body condition and erotic desire. Along with its function as a marker of martial valor and somatic sacredness, the wound, I argue, increasingly is designated in these epic-romances as an interiorizing apparatus, one liable to accrue at any instance into a surplus of unanticipated meaning. As such, the wound becomes an emblem in these texts of what I call the phenomenology of desire—the equation of consummation and loss—as well as the aesthetic and metaphoric mechanism by which these writers seek to overcome it.
The four chapters of this thesis constitute individual but cumulative points of response to the problem of thinking about desire as a type of wound. For Tasso, a wound poses a challenge to physical, psychological, and spiritual integrity, but its remarkable capacity for aestheticization also allows Tasso to envision it as a synthesizer of sacred and erotic affects. For Sidney, the prospect that a wound could define a body as courageous or pathetic, as sacred or corrupt, became both politically and socially troubling, and the New Arcadia, I argue, proleptically attempts to defend Sidney against interpretations of wounds that register them as manifestations of corrupt desire. For Spenser, body fracture and erotic wounding are analogic (indeed, almost indistinguishable), and The Faerie Queene investigates the prospect that confusing these analogies can become an empowering, even revelatory experience. In each of these epic-romances, a wound serves both a literal and a figurative function and, in this way, is established as the foremost image by which these writers imagine strength and mutilation, affect and heroism, epic and romance as being inextricably bound.

Keywords: Torquato Tasso
Edmund Spenser
Early Modern medicine
Renaissance Literature
desire in literature.
body and self
epic-romance
wounds
Philip Sidney
metaphor
Early Modern Literature
Advisor: McCabe, RA
Rydberg ionisation into confined and discrete systems

The energy levels of a hydrogen Rydberg atom approaching a metallic structure are perturbed by the image-charge interaction with the surface. At small atom-surface separations surface ionisation of the Rydberg electron can occur, whereby the electron is transferred to a metal-localised state. In previous studies investigating surface ionisation at bulk metallic surfaces, this state has been part of a conduction band; however this thesis focuses on metallic and structured surfaces where the Rydberg electron transfers into a discrete image-state or hybrid 'well-image state'.
The surface ionisation of hydrogen Rydberg atoms at a Cu(100) projected band-gap surface is investigated experimentally and theoretically. Experimentally, the surface ionisation of an incident beam of hydrogen Rydberg atoms is measured by extraction of the resulting ions. Resonance-enhanced charge transfer is seen for hydrogen Rydberg states that are degenerate with copper-localised image-states. A wavepacket propagation study shows that for on-resonance states the maximum in the surface-ionisation probability is shifted away from the surface by decreasing the collisional velocity.
The discrete hybrid 'well-image states' localised along the surface normal of a thin-film change energy with thin-film thickness. The interaction of hydrogen Rydberg atoms with iron thin films deposited on an insulating substrate is investigated. The preference for electron penetration along the surface normal is seen by the resonance-enhancement of charge transfer at energies where the Rydberg state and well-image state are degenerate. By changing the thickness of the thin film, by in situ depositions, the energies of the well-image state are altered and the Rydberg n-values at which resonances occur, change. At a thickness of 30-monolayer the energetic spacings between the well-image states and the Rydberg states become comparable, and the single well-image state resolution is lost.
A wavepacket-propagation study investigates the interaction of a nanoparticle and low-n hydrogen Rydberg atoms. The nanoparticle has a fully confined potential which at small radii yields well-spaced, fully discrete well-image states. Resonance-enhanced charge transfer occurs when the Rydberg state and the nanoparticle well-image state energy levels are degenerate. However, when there is poor energy matching between the nanoparticle well-image state and the Rydberg atom, no charge transfer is seen i.e. surface ionisation does not occur.
Overall, the work presented here demonstrates the capability of Rydberg-surface studies to identify discrete, high-lying energy levels at specific surfaces.

Keywords: resonant charge transfer
Hydrogen Rydberg atoms
surface ionisation
Advisor: Softley, T
Investigation of the role of the NLP and TDP1 chromatin associated proteins in transcription control in Trypanosoma brucei

The African trypanosome Trypanosoma brucei evades the immune system of the mammalian host by periodically switching its surface coat which is made up of Variant Surface Glycoprotein (VSG). T. brucei shows monoallelic expression of one VSG out of a repertoire of ~1200 genes with the active VSG gene expressed from one of ~15 telomeric expression sites (ESs). The mechanism behind the monoallelic exclusion of ESs is unclear.
NLP was identified as a novel and essential AT-hook protein binding transcriptionally silent simple sequence repeats in T. brucei. I depleted NLP using RNAi in various T. brucei reporter lines containing an eGFP in different transcriptionally silent areas of the genome and monitored derepression of eGFP using flow cytometry. After NLP knock-down, I observed 45-65 fold derepression of silent ESs, and up to 5 fold derepression of other transcriptionally silent areas. Using chromatin immunoprecipitation (ChIP) I found an enrichment of NLP in certain non-transcribed loci including the rDNA spacers. I also found that blocking NLP synthesis results in a rapid fall in levels of the active VSG transcript. Lastly, I discovered using tandem affinity purification (TAP) followed by mass spectrometry that NLP is a part of a novel TbISWI complex in T. brucei, which also includes two previously unidentified protein partners.
The high mobility group B (HMGB) protein family constitutes a major abundant class of non-histone chromatin associated DNA-binding proteins which play a role in chromatin architecture in a wide range of eukaryotes. In T. brucei, the HMGB protein TDP1, which contains two HMG boxes and one DEK C terminal DNA-binding domain, was first identified as binding to VSG ES promoter oligomer sequences. I report that TDP1 is an essential nuclear protein enriched in the nucleolus and expression site body, and is involved in facilitating transcription. Blocking TDP1 synthesis using RNAi mediated knock-down results in approximately 40-90% reduction in transcription of RNA polymerase I transcribed genes. Using ChIP, I find that TDP1 is enriched in the rDNA and on the active VSG ES in bloodstream form T. brucei. Additionally, the relative proportion of TDP1 binding the procyclin promoter compared with the upstream spacer and downstream EP1 genes is greater in procyclic form compared with bloodstream form T. brucei. Lastly, I performed TAP experiments with TDP1 and found that TDP1 interacts with the core histones. These results indicate that TDP1 is an architectural chromatin protein important for transcription control in T. brucei.

Keywords: epigenetics
chromatin regulation
African trypanosomes
Advisor: Rudenko, G
Nella terra di mezzo: cinema e immigrazione in Italia, 1990-2010

The thesis explores the representation of migration to Italy, through the study of a range of films selected for their thematic relevance as much as their aesthetic complexity. Beyond the scope of film analysis, it aims to add a contextualization of the social, political and cultural issues that connect migration and cinema, at the point where film studies and cultural studies converge.

Keywords: Migration
Cinema
Italian
Advisor: Bonsaver, G
An investigation of reasons for Finland's success in PISA

The Programme for International Student Assessment, or PISA, administered by the Organisation for Economic Cooperation and Development, surveyed fifteen-year-olds for the first time in 2000. PISA focuses on mathematics, science, and reading literacy, and intends to undertake a new study every three years. The administration in 2003 added a section that measured problem-solving skills. The results from all three surveys thus far have placed Finland as the highest achieving country in PISA. Finland’s top performances in PISA astonished the educational world. More so than previous cross-national surveys such as TIMSS and PIRLS, PISA has drawn worldwide educational interest towards Finland and its educational system. PISA, unlike TIMSS, does not measure mastery of curriculum, but rather outcomes of education. PISA focuses on real-life applications of knowledge. Triggering global curiosity, the PISA has placed Finland on the itinerary of those wishing to discover the influences behind educational success. This research focuses upon Finland’s historical, cultural, and social context as a part of the Nordic countries and also its immense success in PISA. This project uncovers some of the factors contributing to Finland’s success in education, as indicated by the results in PISA. Finland’s history as a part of both Sweden and Russia has intertwined education with the movement for independence. The struggles after independence, including war and recession, have also reinforced the importance of education within Finnish society. The important status of teachers in Finland, in addition to their high quality, has further enhanced the excellence of the Finnish education system. PISA findings, however, have indicated that the Swedish-speaking Finns score lower than the Finnish-speaking Finns, a phenomenon explored within the research. This project investigates the reasons behind this counterintuitive result. The project incorporates perspectives through interviews with teachers and head teachers from the six sample schools, both Swedish-speaking and Finnish-speaking, Finnish education ministers, PISA creators from the OECD, and Finnish educational researchers and professors responsible for executing PISA in Finland. Their insight, from many different points of view, illuminated different perspectives on PISA and education in Finland.

Keywords: Nordic
comparative education
PISA
Scandinavia
education
Finland
Advisor: Phillips, D
Mathematical modelling of turbidity currents

Turbidity currents are one of the primary means of transport of sediment in the ocean. They are fast-moving, destructive fluid flows which are able to entrain sediment from the seabed and accelerate downslope in a process known as 'ignition'. In this thesis, we investigate one particular model for turbidity currents; the 'Parker model' of Parker, Pantin and Fukushima (1986), which models the current as a continuous sediment stream and consists of four equations for the depth, velocity, sediment concentration and turbulent kinetic energy of the flow.
We propose two reduced forms of the model; a one-equation velocity model and a two-equation shallow-water model. Both these models give an insight into the dynamics of a turbidity current propagating downstream and we find the slope profile to be particularly influential. Regions of supercritical and subcritical flow are identified and the model is solved through a combination of asymptotic approximations and numerical solutions.
We next consider the dynamics of the four-equation model, which provides a particular focus on Parker's turbulent kinetic energy equation. This equation is found to fail catastrophically and predict complex-valued solutions when the sediment-induced stratification of the current becomes large. We propose a new 'transition' model for turbulent kinetic energy which features a switch from an erosional, turbulent regime to a depositional, stably stratified regime. Finally, the transition model is solved for a series of case studies and a numerical parameter study is conducted in an attempt to answer the question 'when does a turbidity current become extinct?'.

Keywords: turbidity currents
density currents
fluid mechanics
mathematical geoscience
gravity currents
Advisor: Fowler, AC
Howell, PD
Information and contracts

This thesis is concentrated broadly in the field of mathematical industrial economics and more specifically upon what is known in the literature as principal-agent relationships. It focuses on investigating the nature of optimal contracts between, say, owners of the firm and the manager appointed by them to run the affairs of the firm or yet again between the owners and the workers employed in the firm.
Chapter 1 introduces by first establishing the background of the analysis and then summarising the results of the thesis. The background consists mainly of implicit contract models, both of the symmetric and asymmetric information kind, and models of moral-hazard. The results of the thesis are contained in four chapters following the introduction.
Chapters 2 and 3 are concerned primarily with the use made of principal agent models in the asymmetric-information implicit contract literature. This literature attempts to explain involuntary unemployment by showing that the inefficiency generated by the asymmetry in information between the principal (firm) and the workers (agent) manifests itself in employment lower than the efficient level. We show instead that results are altered in quite striking ways depending not only on the eventual asymmetry of information but also the asymmetry prevailing, say, when the agent takes his action, but before production occurs.
Chapter 4 makes the case in favour of using the first-order approach in solving principal-agent models by proposing a weakening of the sufficient conditions which make this approach valid. Such weakening extends the range of cases - given by particular configurations of utility and density functions - for which the analytical convenience of the first-order approach may be utilised.
Chapter 5 uses moral-hazard models and the first-order approach to answer the specific question "Should owner-managed firms with limited liability be taxed a higher rate than similar firms with unlimited liability?". The answer is "Yes, but only under certain conditions".
Chapter 6 summarises and draws together the various strands of the arguments presented in the thesis.
Hedge funds: fees, return revisions, and asset disclosure 

This thesis is a collection of three essays on hedge funds with contributions to the empirical understanding of their fees, and their voluntary disclosure of returns and assets under management, using a large consolidation of widely-employed publicly available hedge fund databases.
First, time-series variation in reported fees is analysed using fund launches within hedge fund management companies, and conditioning fees at launch on fund family characteristics. Larger and better performing fund families launch high fee funds. Funds with high management fees at launch do not perform any differently from low fee funds, though funds with high incentive fees marginally outperform. An interval regression technique is proposed to overcome the discrete nature of reported fees.
Secondly, the reliability of voluntary disclosures of financial information is analysed with a different measure of time-variation --- tracking changes to statements of historical performance recorded at different points in time. This uncovers evidence that historical returns are routinely revised. These revisions are not merely random or corrections of earlier mistakes; they are partly forecastable by fund characteristics. Moreover, funds that revise their performance histories, significantly and predictably underperform those that have never revised.
Finally, the availability, and timing, of the selective disclosure of assets under management by funds is examined. More than a third of funds have asset records falling short of returns published. There is evidence of strategic disclosure by funds --- asset reporting drying up after times of fund stress, such as poor performance or outflows. Furthermore, investors should take heed of the greater propensity for shortfall funds to trigger fraud performance flags.
These results suggest that unreliable disclosures: constitute a valuable source of information for current and potential investors; have implications for researchers; and, exhort market regulators to include assets, not just returns, in the debate around mandatory disclosure by financial institutions.

Keywords: Management Companies
Hedge Fund Databases
Hedge Funds
Asset Pricing
Hedge Fund Fees
Revisions
Performance
Assets Under Management
Funds-of-Funds
Voluntary Disclosure
Fraud
Advisor: Ramadorai, T
Improving rapid affinity calculations for drug-protein interactions

The rationalisation of drug potency using three-dimensional structures of protein-ligand complexes is a central paradigm in medicinal research. For over two decades, a major goal has been to find the rules that accurately relate the structure of any protein-ligand complex to its affinity. Addressing this problem is of great concern to the pharmaceutical industry, which uses virtual screens to computationally assay up to many millions of compounds against a protein target. A fast and trustworthy affinity estimator could potentially streamline the drug discovery process, reducing reliance on expensive wet lab experiments, speeding up the discovery of new hits and aiding lead optimization.
Water plays a critical role in drug-protein interactions. To address the often ambiguous nature of water in binding sites, a water placement method was developed and found to be in good agreement with X-ray crystallography, neutron diffraction data and molecular dynamics simulations. The method is fast and has facilitated a large scale study of the statistics of water in ligand binding sites, as well as the creation of models pertaining to water binding free energies and displacement propensities, which are of particular interest to medicinal chemistry.
Structure-based scoring functions employing the explicit water models were developed. Surprisingly, these attempts were no more accurate than the current state of the art, and the models suffered from the same inadequacies which have plagued all previous scoring functions. This suggests a unifying cause behind scoring function inaccuracy. Accordingly, mathematical analyses on the fundamental uncertainties in structure-based modelling were conducted. Using statistical learning theory and information theory, the existence of inherent errors in empirical scoring functions was proven. Among other results, it was found that even the very best generalised structure-based model is significantly limited in its accuracy, and protein-specific models are always likely to be better. The theoretical framework developed herein hints at modelling strategies that operate at the leading edge of achievable accuracy.

Keywords: docking
drug-design
water
scoring-function
molecular-modelling
hydrophobicity
simulations
Advisor: Biggin, P
Garrett, M
Can God be an object of reference?

This thesis is an attempt to give a workable account of 'God', to exhibit its logical status and to show how it can be introduced into language.
The first chapter, after rejecting the view that 'God' is not a referring expression, notes the differences between various types of referring expression, and considers the objections to taking 'God* as a descriptive term, a title, and a proper name. It is concluded that 'God* is the proper name of a spirit, the objections to the other accounts being held to be decisive.
The second chapter explores the notion of a spirit. The view that all persons must be corporeal is rejected and a concept of a person is developed which shows how it is possible for persons, both corporeal and incorporeal, to be identified and individuated. Finally it is shown how it is possible to predicate emotions of incorporeal persons.
The third chapter shows how it is possible, given the nature of God, to fix the reference of 'God'. It is held that certain referring expressions have their references fixed by playing a role in such an interpretation of experience. Religious faith is shown to be such an interpretation of experience, able to fix the reference of referring expressions, because it has criteria for determining the validity of certain statements made within the interpretation. Finally it is shown how the reference of 'God* can be fixed within this interpretation.