VictorJuiz/thesis huggingface dataset:
Information theoretic resources in quantum theory
Keywords: entanglement
discord
quantum operations
quantumness
quantum mechanics
quantum information
physics

Resource identification and quantification is an essential element of both classical and quantum information theory. Entanglement is one of these resources, arising when quantum communication and nonlocal operations are expensive to perform. In the first part of this thesis we quantify the effective entanglement when operations are additionally restricted to account for both fundamental restrictions on operations, such as those arising from superselection rules, as well as experimental errors arising from the imperfections in the apparatus. For an important class of errors we find a linear relationship between the usual and effective higher dimensional generalization of concurrence, a measure of entanglement.
Following the treatment of effective entanglement, we focus on a related concept of nonlocality in the presence of superselection rules (SSR). Here we propose a scheme that may be used to activate nongenuinely multipartite nonlocality, in that a single copy of a state is not multipartite nonlocal, while two or more copies exhibit nongenuinely multipartite nonlocality. The states used exhibit the more powerful genuinely multipartite nonlocality when SSR are not enforced, but not when they are, raising the question of what is needed for genuinely multipartite nonlocality. We show that whenever the number of particles is insufficient, the degrading of genuinely multipartite to nongenuinely multipartite nonlocality is necessary.
While in the first few chapters we focus our attention on understanding the resources present in quantum states, in the final part we turn the picture around and instead treat operations themselves as a resource. We provide our observers with free access to classical operations - ie. those that cannot detect or generate quantum coherence. We show that the operation of interest can then be used to either generate or detect quantum coherence if and only if it violates a particular commutation relation. Using the relative entropy, the commutation relation provides us with a measure of nonclassicality of operations. We show that the measure is a sum of two contributions, the generating power and the distinguishing power, each of which is separately an essential ingredient in quantum communication and information processing. The measure also sheds light on the operational meaning of quantum discord - we show it can be interpreted as the difference in superdense coding capacity between a quantum state and a classical state.
Elephant versus other browsers’ long-term influences on savanna woodland dynamics
Keywords: savanna ecology
zoology
ungulates
ecosystems
competition
African elephants
ecology

A crucial question in the debate about reintroducing elephant culling is whether the long-term effects of elephants and mesobrowsers on woodlands are similar. Sufficiently high biomass-densities of mesobrowsers may, following reduction or removal of elephants, continue to heavily impact earlier life-history stages of a similar suite of woody plants that elephant impacted, preventing these species from maturing. Thus a similar end-point for woodland structure and composition is achieved. No study exists in the literature where woody plant and habitat utilisation of the savanna browser guild has been determined in the same locality over the same period.
A review of 49 years of literature implied that the two groups impact the same core woody-species in the same habitats. Dietary and habitat utilisation of guild members was determined in Hluhluwe-iMfolozi Park, South Africa. A small suite (n = 8) of woody species formed the core diet of all guild members. Herbivores’ densities were determined using a novel GIS approach; all members of the guild showed extensive overlap in habitat use. GPS collars and a GIS were then used to detect zones of different density of impala in the landscape, thus defining, for the first time, a natural fine-grain browsing gradient. Densities of woody seedlings were significantly less (average 48% reduction) in areas of high versus low impala density. A simple browse-browser model, incorporating, in a novel approach, functional groups of plant species, was parameterised from these results and an extensive review of the literature. Outputs suggest that over the long-term (100 years), impala will have a similar impact on woodland structure as elephant. An apparently strong synergistic effect between impala and elephant impact, suggests that reduction or removal of either impala or elephant will radically reduce long-term destruction of woodlands.
In smaller or medium sized reserves, where control of mesobrowser populations is practical, profitable and more acceptable than elephant culling, these findings imply a re-direction of management efforts. Management should consider the biomass-density of both groups, rather than just focus on the system’s perceived ‘keystone’ species. Such principles may also apply to temperate and other systems.
'Flippant dolls' and 'serious artists': professional female singers in Britain, c.1760-1850
Keywords: Singers
Professions
Singing
Arts
Professionalism
Theatre
Performance
Gender
Professionalization
Artistry
Women
Music

Existing accounts of the music profession argue that between 1750 and 1850 musicians acquired a new identity as professional ‘artists’ and experienced a concomitant rise in their social and cultural status. In the absence of sustained investigation, it has often been implied that these changes affected male and female musicians in similar ways. As this thesis contends, this was by no means the case. Arguments in support of female musical professionalism, artistry, and their function in public life were made in this period. Based on the gender-specific nature of the female voice, they were an important defence of women’s public engagement that has been overlooked by gender historians, something which this thesis sets out to correct. However, the public role and professionalism of female musicians were in opposition to the prevailing valorisation of female domesticity and privacy. Furthermore, the notion of women as creative artists was highly unstable in an era which tended to label artistry, ‘genius’ and creativity as male attributes. For these reasons, the idea of female musicians as professional artists was always in tension with contemporary conceptions of gender, making women’s experience of the ‘rise of the artist’ much more contested and uncertain compared to that of men. Those advocating the female singer as professional artist were a minority in the British musical world. Their views co-existed alongside very different and much more prevalent approaches to the female singer which had little to do with the idea of the professional artist. Through examining debates about female singers in printed sources, particularly newspapers and periodicals, alongside case studies based on the surviving documents of specific singers, this thesis builds a picture of increasing diversity in the experiences and representations of female musicians in this period and underlines the controlling influence of gender in shaping responses to them.
A search for the Standard Model Higgs boson via its decay to tau leptons and W bosons at the ATLAS detector
Keywords: particle physics higgs tau atlas cern lhc

Understanding the origin or Electroweak symmetry breaking within the Standard Model was a key motivation for the construction of the Large Hadron Collider (LHC) experiment at CERN. This thesis presents a search for evidence of Higgs boson production in the 4.7 fb−1 of collision data recorded at a centre-of-mass energy of 7 TeV at the ATLAS detector during 2011.
This search is focused on signal events in which a Higgs boson is produced in the mass range 100 < mH < 180 GeV/c2 and subsequently decays to a pair of W bosons or a pair of tau leptons to final states with one hadronically decaying tau lepton and one light lepton. After an event selection criteria has been applied, the number of events in this data sample is consistent with the total background estimate and an upper limit is placed on the SM Higgs boson production rate at 95% confidence level. In addition, the prospects for measuring the SM Higgs coupling strength to tau leptons with the associated Higgs production channels and the full LHC dataset are also presented.
Domain evolution processes in ferroelectric ceramics
Keywords: domain structure
piezoresponse force microscopy
ferroelectrics
Monte Carlo simulation

The aim of this doctoral research is to understand domain evolution processes in ferroelectrics using piezoresponse force microscopy (PFM) and Monte Carlo simulation. The results provide improved knowledge of domain evolution processes, and systematic experimental methods for research on domain evolution.
There has been extensive previous research on domain evolution in ferroelectrics, but the research was mainly constrained to simple domain patterns. However, ferroelectric domains tend to form complex patterns that generate low-energy domain configurations. In this research, several methods such as statistical analysis of PFM data, ex situ/in situ PFM observation under electrical/mechanical loading and combining PFM with electron backscatter diffraction are employed to study domain evolution processes in complex domain patterns. The results show that domain switching almost always takes place by the evolution of pre-existing domain patterns, rather than direct flipping of polarization. Also the net effect of domain evolution processes follows a primary principle that positive work is done by external loads. But this principle is not always followed for microscopic switching processes. Multiple types of domain switching occur simultaneously, and occasionally an overwriting process involves unfavourable as well as favourable domain switching. Domain switching is significantly constrained by the pre-existing domain patterns. Meanwhile, angle-resolved PFM is developed for the systematic interpretation of PFM signal. Using lateral PFM images taken from multiple sample orientations, angle-resolved PFM maps are generated based on the angle of phase reversal in the PFM signal. The resulting maps reliably show complex domain patterns which may not appear in vertical and lateral PFM images.
A model of domain evolution is developed using Monte Carlo simulation. Polarization switching by electric field and mechanical stress in the model is shown to take place via the motion of domain walls between pre-existing domains. Typical domain broadening processes are reproduced through this simulation.
Comprehension of grammar: normal and abnormal development
Keywords: child development
grammar
language comprehension

This thesis is in two parts. Part 1 reviews work on comprehension of grammatical structure in children and describes the development of a new Test for the Reception of Grammar (TRCG). TROG assesses understanding of a variety of grammatical contrasts using a format where the child is required to select from an array a picture to correspond to a phrase or sentence spoken by the tester. Results from 280 normal children aged from 3—6 to 13-2 are presented. It is shown that several grammatical structures are not completely mastered by age 13. and in some instances it appears that the accepted rule that comprehension precedes production is contravened. Data on reliability and validity of TROG are also presented.
Part 2 is Concerned with the application of TROG to 73 children with receptive and expressive developmental language disorders. It is shown that the majority of these children perform below age level both on TROG and on a test of receptive vocabulary. Further. there is a strong relationship between performance on TROG and grammatical complexity of expressive speech. Structures involving decoding of .word order appear to give these children particular difficulty, over and above their general comprehension deficits. Results are discussed in relation to psychological theories of developmental language disorders, and implications for the classification of these disorders are considered.
Manipulating single atoms with optical tweezers
Keywords: dipole trap
optical tweezers
single atom
laser cooling
quantum information
quantum computing

Single atoms are promising candidates for physically implementing quantum bits, the fundamental unit of quantum information. We have built an apparatus for cooling, trapping and imaging single rubidium atoms in microscopic optical tweezers. The traps are formed from a tightly focused off-resonant laser beam, which traps atoms using the optical dipole force. The traps have a diameter of ~1 μm and a depth of ~1 mK.
The novelty of our approach is the use a digital mirror device (DMD) to generate multiple independently movable tweezers from a single laser beam. The DMD consists of an array of micro-mirrors that can be switched on and off, thus acting as a binary amplitude modulator. We use the DMD to imprint a computer-generated hologram on the laser beam, which is converted in to the desired arrangement of traps in the focal plane of a lens. We have developed fast algorithms for calculating binary holograms suitable for the DMD. In addition, we use this method to measure and correct for errors in the phase of the wavefront caused by optical aberrations, which is necessary for producing diffraction-limited focal spots.
Using this apparatus, we have trapped arrays of up to 20 atoms with arbitrary geometrical arrangements. We exploit light-assisted collisions between atoms to ensure there is at most one atom per trapping site. We measure the temperature of the atoms in the traps to be 12 μK, and their lifetime to be 1.4 s. Finally, we demonstrate the ability to select individual atoms from an array and transport them over a distance of 14μm with laser cooling, and 5 μm without.
LYVE-1 and hyaluronan - a molecular velcro
Keywords: LYVE-1
Hyaluronan
Lymphatics

The lymphatic system comprises a network of vessels whose primary functions are the maintenance of extracellular fluid balance and the transport of antigen-presenting cells from the periphery to the lymph nodes, thus facilitating immunological surveillance of the tissues and activation of adaptive immunity. In malignant disease, the lymphatics are both a route for dissemination and a reservoir for metastatic cancers such as cutaneous melanoma and breast carcinoma, where lymph node involvement is an early indicator of prognosis. Yet, despite such obvious importance in disease, the fundamental biology of the lymphatics is poorly understood and critical mechanisms such as those underlying trafficking of dendritic and tumour cells have been largely overlooked.
The focus of this thesis is lymphatic vessel endothelial hyaluronan receptor LYVE-1, and the regulation of its binding to the extracellular matrix glycosaminoglycan, hyaluronan (HA). Found selectively on the surface of lymphatic vessels, but sharing many of the features of the leukocyte homing receptor CD44, LYVE-1 appears a likely candidate for regulation of lymphatic trafficking during the stage at which cells migrate into the vessel. However, the precise function of LYVE-1 in recent years has remained enigmatic, not least because the native receptor is subject to post-translational modification with sialic acid, with the effect that HA binding is inhibited in lymphatic endothelium. The results of this thesis demonstrate that sialylation of LYVE-1 is not a short term regulatory modification, but rather a longer term mechanism that imposes a requirement for higher order receptor complex formation or HA crosslinking to achieve stable binding. This implies that native LYVE-1 is an active HA binding protein even when sialylated, with implications for our understanding of the role played by the receptor in HA uptake and metabolism, and transmigration of lymphatic endothelium by migratory leukocytes. Like CD44, HA binding to LYVE-1 is dependent on multivalent interactions between receptor and ligand, and may be enhanced by processes that increase the avidity of the interaction. Here for the first time it is shown that the native LYVE-1 molecule on lymphatic endothelium may be activated to bind HA following clustering of the receptor, or presentation of HA in a cross-linked form, such as that resulting from incubation with the HA binding protein TSG-6.
Aziridines and aziridinium intermediates in the asymmetric synthesis of beta-substituted-alpha-amino acids and 1,2,3,4-tetrahydroisoquinolines  
Keywords: Aziridiniums
Aziridines
Lithium Amide
Amino Acids
Tetrahydroisoquinolines

This thesis is concerned with the development of methodology for the regioselective ring-opening of aziridines and aziridinium intermediates and its subsequent application to the asymmetric synthesis of β-substituted-α-amino acids and 1,2,3,4-tetrahydroisoquinolines.
Chapter 1 introduces methods for the formation of aziridines and aziridinium ions and focusses on their utility as intermediates in synthesis.
Chapter 2 describes studies into the synthesis of aziridines from enantiopure α-hydroxy-β-amino esters and their subsequent conversion to the corresponding β-hydroxy-α-amino acids via either a regioselective ring-opening with Cl3CCO2H, or a rearrangement promoted by Cl3CCO2H. Application of this procedure to both syn- and anti-configured substrates enabled the syntheses of (S,S)-allo-threonine, (2R,3S)-threonine, (R,R)-3-hydroxyphenylalanine and (2S,3R)-3-hydroxyphenylalanine.
Chapter 3 details attempts to truncate the synthesis described in Chapter 2 by investigating the synthesis of enantiopure anti-β-hydroxy-α-amino acids via the intermediacy of aziridinium ions. These studies culminated in the development of a regioselective and stereospecific one-pot aziridinium formation and ring-opening protocol, leading to the synthesis of a range of C(3)-aryl and C(3)-alkyl substituted anti-β-hydroxy-α-amino acids.
Chapter 4 discusses the conversion of enantiopure anti-α-hydroxy-β-amino esters to anti-β-fluoro-α-amino esters via the regioselective and stereospecific ring-opening of an aziridinium intermediates in situ. The subsequent development of a one-pot deprotection strategy leads to a concise and expedient synthesis of anti-β-fluorophenylalanines. The extension of this methodology to access a representative anti-α,β-diamino acid is also demonstrated.
Chapter 5 describes the development of a one-pot diastereoselective rearrangement of enantiopure α-hydroxy-β-amino esters to 1,2,3,4-tetrahydroisoquinolines. The substrate scope of this reaction manifold is examined and application to the asymmetric synthesis of enantiopure 1,2,3,4-tetrahydroisoquinolines also discussed.
Chapter 6 contains full experimental procedures and characterisation data for all compounds synthesised in Chapters 2, 3, 4 and 5.
Synthesis of complex γ-lactones mediated by manganese(III)
Keywords: lactone
quaternary
manganese
stereocentres

This thesis details the development of manganese(III) acetate-mediated oxidative radical cyclisation methodology. In particular, the use of radicals to form complex, highly sterically congested and strained carbo- and heterocycles in a stereocontrolled manner is described.
Chapter 1 gives a summary of the literature regarding three key areas relevant to this work. Radical reaction mechanisms are introduced, including the use of transition metals and lanthanides in C-centred radical cyclisations. The formation of highly sterically congested vicinal all-carbon quaternary stereocentres is also discussed. Finally, the use of radical cyclisation methodology for the synthesis of complex cyclic structures and applications in natural product total synthesis is examined.
Chapter 2 gives an account of the manganese(III) acetate-mediated cyclisation of 5-pentenyl malonates bearing a terminal aryl group. The effects of the aryl group are tested with a range of electronically varied substituents. The formation of bi- and tricyclic cyclopentane-lactones bearing adjacent quaternary-quaternary-tertiary stereocentres is demonstrated.
Chapter 3 demonstrates the synthesis of highly strained tricyclic bis-lactones. The metal complexes manganese(III) acetate and cerium(IV) ammonium nitrate are shown to give complementary stereoselectivity across a range of cyclisation substrates. Possible synthetic applications of tricyclic bis-lactones are also investigated.
Chapter 4 details an asymmetric formal synthesis of the proteasome inhibitor salinosporamide A. An oxidative radical cyclisation forms the key heterocycle in Danishefsky’s synthesis of this biologically important molecule, and showcases the use of the radical chemistry in natural product synthesis. Full experimental details, selected NMR spectra, and X-ray crystallographic data are also provided.
Bayesian numerical analysis: global optimization and other applications
Keywords: gaussian processes
global optimization
radial basis functions
surrogate approximation

We present a unifying framework for the global optimization of functions which are expensive to evaluate. The framework is based on a Bayesian interpretation of radial basis function interpolation which incorporates existing methods such as Kriging, Gaussian process regression and neural networks. This viewpoint enables the application of Bayesian decision theory to derive a sequential global optimization algorithm which can be extended to include existing algorithms of this type in the literature. By posing the optimization problem as a sequence of sampling decisions, we optimize a general cost function at each stage of the algorithm. An extension to multi-stage decision processes is also discussed.
The key idea of the framework is to replace the underlying expensive function by a cheap surrogate approximation. This enables the use of existing branch and bound techniques to globally optimize the cost function. We present a rigorous analysis of the canonical branch and bound algorithm in this setting as well as newly developed algorithms for other domains including convex sets. In particular, by making use of Lipschitz continuity of the surrogate approximation, we develop an entirely new algorithm based on overlapping balls.
An application of the framework to the integration of expensive functions over rectangular domains and spherical surfaces in low dimensions is also considered. To assess performance of the framework, we apply it to canonical examples from the literature as well as an industrial model problem from oil reservoir simulation.