VictorJuiz/thesis huggingface dataset:
Physiologically-mediated Interaction between Children with Profound Disabilities and Their Environment
Keywords: disability
autonomic nervous system

This thesis explores the physiologically-mediated interactions between children with profound disabilities and their environment. Using a structure inspired by the musical theme and variation compositional form, the concept of using physiological signals to enrich person-environment interaction will be addressed in two themes. The first theme explores how children with profound disabilities can use their physiological signals to interact with their environment. The variations on this theme: 1) appraise the literature and establish that peripheral autonomic nervous system signals can be controlled by mental activities; 2) present an algorithm that classifies an individual’s mental state using patterns of electrodermal activity to an accuracy of over 80%, and; 3) discusses the challenges with and potential solutions to creating an physiologically-based interaction pathway for children with profound disabilities. The second theme explores how physiological signals can be used to assess the effect of the environmental milieu on a child with profound disabilities. The variations on this theme: 1) demonstrate the effects of the built environment on the life activities of a severely disabled individual by developing and evaluating the effects of a custom-tailored computer access technology; 2) illustrate how the physiological signals of profoundly disabled children are influenced by their social environment by studying the effect of Therapeutic Clowns on children in a long-term rehabilitation setting; and 3) illustrate how differential physiological responses to sounds in the environmental milieu can be used to inform and improve voluntary physiologically-mediated person-environment interaction. The coda of the thesis presents a conceptual framework that has the potential to enrich the interaction between profoundly disabled children and their environment, using music generated from physiological signal patterns to modify their environmental milieu, constructs of personhood and their identity.
The Third-phase of the Yungang Cave Complex—Its Architectural Structure, Subject Matter, Composition and Style
Keywords: Yungang Cave Temples
Images
Shanxi Buddhist Caves
Buddhist Cave temples
donors
patrons
Tan Yao
Longmen Buddhist Caves
Shitanghui Buddhist Caves
Monastic life and Buddhist art
Emperor Xiaowen
Lady Feng

Abstract The Yungang Cave Complex in Shanxi province is one of the largest Buddhist sculpture repositories produced during the Northern and Southern Dynasties. This thesis argues that the iconographic evolution of the Yungang caves underwent three developing phases which can be summarized as the five Tan Yao Caves phase, the transitional period, and the sinicized third-phase under the reigns of five Northern Wei (386-534) emperors Wencheng 文成 (452-465), Xianwen 獻文 (466-471), Xiaowen 孝文(471-499), Xuanwu 宣武 (500-515) and Xiaoming 孝明 (516-528). This dissertation studies the Yungang third-phase caves, namely those caves executed after the capital was moved from Pingcheng 平城 to Luoyang 洛陽in the year 494. It focuses primarily on what we call the western-end caves, which are composed of all the caves from cave 21 to cave 45, and as cave 5-10 and cave 5-11 are typical representations of the third-phase and even today are well preserved, they are also included in this study. Using typology method, as well as primary literary sources, this study places the western-end caves in their historical, social and religious context while focusing on four perspectives: architectural lay-out, iconographic composition, subject matter and style of representation. It deals with such questions as: what these images represent, what is their connection with Buddhist literature, what is the origin of the style of the western-end caves, what is the relationship between sculpture and painting, what is the relationship between the monastic life and Buddhist art, what was the status of Yungang after the transfer of the capital to the south, and who were the patrons. This study sheds new light on the changes in the iconographic motifs over the time from the first-phase to the third-phase and constructs a timeline for the sequence of construction of the western-end caves. The study also investigates the iconographical inter-relationship between the Yungang third-phase caves and those in the Longmen and to a lesser extent, the Gongxian complexes, as well as some relatively small caves in Shanxi province in order to trace the spread of the “Yungang Style.” This will map out the evolution in Buddhist iconographical style throughout the Central Plain of China. Although the caves of the first two phases have been studied extensively, this study is the first comprehensive examination of the Yungang third-phase caves. It is also the first investigation of the interrelationship between the Yungang style and that of other sites such as Longmen and Gongxian, as well as individual caves in the Shanxi area. This work is based on a broad consultation of primary text material and, most importantly, on first hand site observations by the researcher, which are documented by an extensive photographic record.
Poetic Properties: Legal Forms and Literary Documents in Early English Literature
Keywords: Old English Law
Wulfstan
Cnut
First Worcester Fragment
Laȝamon
South English Legendary
Piers Plowman
Mum and the Sothsegger
Diplomatics
Textual Criticism

This thesis argues that the Middle English alliterative prosody of the Piers Plowman tradition was influenced by a discourse combining law, history, homily and poetry which was inherited from the administrative practices of the Anglo-Saxon period. As literary and legal textual genres developed recognizably distinct formal characteristics in the later Middle Ages, the combination of homiletic rhetoric and alliterative sound-patterning evoked a surviving discourse in which the formal characteristics of poems and documents were less clearly distinguished. Thus insofar as it evoked Anglo-Saxon textual culture, Piers Plowman provided a formal model which was particularly suitable to criticisms of political institutions that consolidated their power by developing new distinctions between the genres of bureaucratic texts. In each of the texts and traditions studied – Wulfstan’s homiletic law code I–II Cnut and its Latin translations, The First Worcester Fragment, Laȝamon’s Arthurian Brut chronicle-poem, The South English Legendary "Life of St. Egwine", and the Piers Plowman tradition poem Mum and the Sothsegger – apparently “literary” devices are used to authorize historically-based “legal” claims, particularly on behalf of ecclesiastical institutions looking to maintain their local influence in the face of increasingly consolidated royal administrative authority. Though oaths played a much less important procedural role after the Norman Conquest than they did in the Anglo-Saxon period, the appearance of "creative" authenticating procedures in "commemorative" texts created the appearance of orality to post-Conquest readers, to criticize a government which claimed its English "common" law to originate in the remotest recorded antiquity, even as it abandoned the practices actually recorded in the earliest surviving law codes and documents to be written in England. Comparing these texts allows a deeper understanding of their shared authenticating strategies, and also a re-appraisal of the methods we use to describe the relationships between medieval documents and authors, literature and law, texts and contexts. Appended to the dissertation is an edition of the SEL "Life of St. Egwine." Because Egwine's hagiographic tradition is so thematically invested in political concerns and closely interconnected with legal documents attributed to Egwine himself, the edition provides an opportunity to take a "disjunctively" literary and diplomatic approach to the tradition, in the process exploring some of the practical implications of the larger theoretical issues raised by the thesis as a whole.
Evolving Paradigms in the Treatment of Hepatitis B
Keywords: Hepatitis B
Meta-analysis
Bayesian
Utility

Hepatitis B is a serious global health problem with over 2 billion people infected worldwide and 350 million suffering from chronic hepatitis B (CHB) infection. Infection can lead to chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC) accounting for 320,000 deaths per year. Numerous treatments are available, but with a growing number of therapies each with considerable trade-offs, the optimal treatment strategy is not transparent. This dissertation investigates the relative efficacy of treatments for CHB and estimates the health related quality of life (HRQOL) and health utilities of mild to advanced CHB patients. A systematic review of published randomized controlled trials comparing surrogate outcomes for the first year of treatment was performed. Bayesian mixed treatment comparison meta-analysis was used to synthesize odds ratios, including 95% credible intervals and predicted probabilities of each outcome comparing all currently available treatments in HBeAg-positive and/or HBeAg-negative CHB patients. Among HBeAg-positive patients, tenofovir and entecavir were most effective, while in HBeAg-negative patients, tenofovir was the treatment of choice. Health state utilities and HRQOL for patients with CHB stratified by disease stage were elicited from patients attending tertiary care clinics at the University Health Network in Toronto. Respondents completed the standard gamble, EQ5D, Health Utilities Index Mark 3 (HUI3), Short-Form 36 version-2 and a demographics survey in their preferred language of English, Cantonese or Mandarin. Patient charts were accessed to determine disease stage and co-morbidities. The study included 433 patients of which: 294 had no cirrhosis, 79 had compensated cirrhosis, 7 had decompensated cirrhosis, 23 had HCC and 30 had received liver transplants. Mean standard gamble utilities were 0.89, 0.87, 0.82, 0.84 and 0.86 for the respective disease stages. HRQOL in CHB patients was only impaired at later stages of disease. Neither chronic infection nor antiviral treatment lowered HRQOL. Patients with CHB do not experience lower HRQOL as seen in patients with hepatitis C. The next step in this area of research is to incorporate the estimates synthesized by the current studies into a decision model evaluating the cost-effectiveness of treatment to provide guidance on the optimal therapy for patients with HBeAg-positive and HBeAg-negative CHB.
Emergent Inpatient Admissions and Delayed Hospital Discharges
Keywords: hospital discharge
system dynamics

Emergency Department (ED) congestion can be better understood by examining overall system impacts, in particular inpatient admissions and discharges. This study first investigates trends of inpatient admissions, volume of patients in the ED who have been admitted (ED “boarders”), length of stay, and bed resources of three major admitting services at our teaching institution. It was found that patients admitted to the General Internal Medicine (GIM) service constituted the majority of ED boarders by default rather than design, as GIM served as a safety net for specialty services. This study investigates operational factors that impact discharge and found that day of the week and holidays followed by team organization and scheduling are significant predictors of daily variation in discharge rates. Based on these results, next, a system dynamics computer simulation was built to test the impact of various discharge smoothing strategies on the number of ED boarders. Next, this study uses the framework and tools of system dynamics methodology to design a conceptual model of the ED boarder problem that may be used as a generalizable roadmap to create sustainable improvements in ED congestion. Finally, this study introduces a novel real time metric of hospital operational discharge efficiency- daily discharge rate – to bring focus on the underlying causes of discharge variation and help indicate opportunities for improvement.
Development and Implementation of Gene Ontology Cluster Analysis of Protein Array Data
Keywords: molecular biology
bioinformatics
protein array
cluster
Gene Ontology
partitioning around medoids
protein-protein interaction
cancer
LNX1
PDZ

Decoding the genomes from organisms that encompass all taxonomies provides the foundation for extensive, large scale studies of biological molecules such as RNA, protein and carbohydrates. The high-throughput studies facilitated by the existence of these genome sequences necessitate the development of new analytic methods for the interpretation of large sets of results. The work herein focuses on the development of a novel clustering method for the analysis of protein array results and examines its utilization in the analysis of integrated interaction data sets. Sets of proteins that interact with a molecule of interest were clustered according to their functional similarity. The simUI distance metric in the statistical analysis package BioConductor was applied to measure the similarity of two proteins utilizing the assembly of their Gene Ontology annotation. Clusters were identified by partitioning around medoids and interpreted using the summary label provided by the Gene Ontology annotation of the medoid. The utility of the method was tested on two published yeast protein array data sets and shown to allow interpretation of the data to yield novel biological hypotheses. We performed a protein array screen using the E3 ubiquitin ligase and PDZ domain-containing protein LNX1. We combined these results with other published LNX1 interactors to produce a set of 220 proteins that was clustered according to Gene Ontology annotation. From the clustering results, 14 proteins were selected for subsequent examination by co-immunoprecipitation, of which 8 proteins were confirmed as LNX1 interactors. Recognition of 6 proteins by specific LNX1 PDZ domains was confirmed by fusion protein pull-downs. This work supports the role of LNX1 as a signalling scaffold. The interpretation of protein array results using our novel clustering method facilitated the identification of candidate molecules for subsequent experimental analysis. Thus our analytical method facilitates identification of biologically relevant molecules within a large data set, making this method an essential component of complex, high-throughput experimentation.
Prostate Cancer Websites: One Size Does Not Fit All
Keywords: prostate cancer
eHealth
information filtering
information tailoring
recommender system
patient education

A North American man has approximately a one in six chance of being diagnosed with prostate cancer in his lifetime. In most cases, there is no clearly optimal treatment, so he may be invited to participate in a treatment decision between several medically reasonable options, each with potential short- and long-term side effects. Information needs are high at diagnosis and can continue to be elevated for years or decades. Many men and their families seek information online, where, due partly to the array of websites available and high variation in information preferences, it can be difficult to find personally relevant and useful websites. This research sought to address this issue by developing methods to categorize prostate cancer websites and exploring quantitative and qualitative relationships between websites, information-seekers, and individuals’ assessments of websites. The research involved a series of three studies. In the first study, 29 men with prostate cancer participated in a needs assessment involving questionnaires, an interview, and interaction with a prototype website. In the second study, a detailed classification system was developed and applied to a set of forty websites selected to be representative of the variety of prostate cancer websites available. The third (online) study collected clinical, cognitive, and psychosocial details from 65 participants along with their ratings of websites from study two. A number of hypotheses were tested. One finding was that, compared to men with greater trust, men with lower trust in their physician tended to judge commercial websites as less relevant and useful, and found websites with descriptions of personal experiences more relevant and useful. Analyses also addressed a number of exploratory questions, including whether website and individual attributes might predict preferences for websites. Using discriminant analysis on 80% of the data, two functions were identified that predicted ratings significantly better than chance. These relationships were then validated with 20% of the data held back for testing. The results are discussed in terms of their implications for information tailoring and recommender systems for prostate cancer patients searching for information online. Limitations of the current research and recommendations for future research are also presented.
Lamentations of a Lovelorn Soul: Self-portraits in the Poetry of Dahlia Ravikovitch
Keywords: Dahlia Ravikovitch
Hebrew Poetry
Layers of Hebrew Language and Literature
Self-portraiture

The poetry of Dahlia Ravikovitch presents as self-writing nestled in the wide embrace of non-linear écriture féminine. Each poem offers a glimpse of the persona: body and soul, the music of her voice and the perspective of her spirit. Together the poems comprise verbal self-portraits of a lovelorn soul, torn between impulses to fully remember and deliberately forget. Through years of love, life, disappointment, bouts of depression and renewed promise, Dahlia Ravikovitch continued to compose. Through the crystals of poetry the speaker examines, from varying angles and in multiple refractions of light, those figures of alterity who are her self. For Ravikovitch poetry was the only neutral space in which her self could comfortably exist and, even so, not always. The poet-persona experiences love in unsuitable proportions. She receives too little; she goes ‘overboard’ and ‘out of bounds’ in giving too much. She experiences love, even when accessible, as an affliction. She suffers love. She laments love. The persona performs her malaise through contrasting physical sensations, idiosyncrasies and profound cravings. Her personal thermostat is erratic. She exhibits pronounced wardrobe-predilections. Her throat reacts to a flow of eros and creative vitality or lack thereof. She yearns for pure memory and thirsts for pure essence. The speaker’s gallery displays an elaborate montage of a golden apple endowed with gifts of wisdom, eros, poetry and passion, alongside portraits of a royal chanteuse and a skilled scribe. Crucial brushstrokes illuminate lovers and sinners, souls in flames, shipwrecks, lyric-expressive throats in various states of constriction and release, as well as voices of collective responsibility. Ravikovitch encrypts her poetry with rich resources of biblical, rabbinic, medieval and early modern Hebrew literature. She forwards the linguistic and literary resonance of these layers. She innovates upon their motifs through feats in the dimensions of feminine writing, intertextual engagements and postmodern poetics.
Un/Disciplined Performance: Nonprofessionalized Theatre in Canada's Professional Era
Keywords: Canadian
theatre
Edmonton
Toronto
Bourdieu
Foucault
amateur
professional
drama
institutions
public policy
Canada
University College
University of Toronto
Walterdale
Alumnae Theatre
discourse analysis
cultural production
field theory
Actors' Equity
disciplines
historiography

The discourse of Western theatre practice is founded on, and maintained as, a legitimizing struggle between the terms “professional” and “amateur.” This study moves beyond the traditional signifiers of Canadian amateur theatre—the Little Theatre Movement, the Dominion Drama Festival and connotations of “inferior” and “dilettantish”—to examine two nonprofessionalized companies that have witnessed the professionalization of Anglo-Canadian theatre in order to argue for the relevance and vitality of contemporary “nonprofessionalized” theatre practices. By drawing from Pierre Bourdieu’s field theory and Michel Foucault’s discourse theory and theories of formations of disciplines, this study argues that theatre professions seek to discipline, delegitimize and exclude nonprofessionalizing practices in order to gain capital (economic, social and cultural) at the expense of the creative freedoms inherent in nonprofessionalized work. It also considers the ways in which theatre scholarship omits critical discussion of amateur practice and how the term “amateur” is co-opted as a clouded pejorative signifier and erased by the contested term “community” within theatre discourse (institutions, practices and the Canadian imaginary). Following a case study approach based on archival documents, the study provides the foundation for a social history of Alumnae Theatre Company (1918- ), beginning with its early years as part of the University of Toronto’s University College Alumnae Association, by examining the relationship between amateur theatre practice and campus philanthropy, followed by Alumnae’s impact on Toronto’s professionalizing theatre scene in the context of alterity in Canadian theatre discourse. It then examines Walterdale Theatre Associates’ (1958- ) relationship to the emerging theatre profession before and after the opening of Edmonton’s Citadel Theatre in 1965 to argue that Walterdale benefits the profession and its professionalizing artists while negotiating complex concerns over institutionalization. Their longevity is explained, in part, by the fact that both companies operate “as if” professional, yet outside of professionalized disciplinary regimes.
Three Essays in Applied Microeconomics
Keywords: Discrete choice
Spatial differentiation
Retail banking
Household model
Parental investment
Matchmaker

In this thesis, I investigate economic and policy implications of individual choice decisions, including consumers’ choices among differentiated products and households’ decisions on intra-household resource allocations. In the first chapter, I develop a consumer demand model for US retail banking services in which consumers have preference over the geographical convenience of their banks’ networks. The purpose of the study is to identify consumers’ taste for branch network convenience in the US banking industry and to assess the effect of this demand motive on bank revenues, consumer surplus, and market structure. I show that consumers value the geographical convenience of their bank branch network to a large extent. Specifically, a branch that is one mile closer is equivalent to a branch with a 0.4 percent higher annual interest rate. Furthermore, consumers value proximity of the branch network to both their residence and workplace. The counterfactual experiment shows that banks with a larger number of branches enjoy greater network benefits in terms of revenue. Meanwhile, consumers benefit from the reduction in their expected travel distance by choosing depository institutions with large-scale networks. The second chapter examines how parents adjust bride-prices and land divisions to compensate their sons for differences in their schooling expenditures in rural China. The model is tested using data from a unique household interview survey carried out in Hebei Province. The main estimate implies that when a son receives one yuan less in schooling investment than his brother, he will obtain 0.7 yuan more in observable marital and post-marital transfers as partial compensation. This marginal compensation estimate is quantitatively larger than any comparable estimate using North American data, suggesting that the unitary model is a useful model of resource allocation for sons in traditional agricultural families. As a supplement to Chapter 2, Chapter 3 investigates matchmakers’ negotiation role in rural Chinese marriages and its impact on marital transfer from the parents to the children at the time of marriage. Using a unique household-level dataset collected in Hebei province, I find that a negotiator’s involvement can raise the total marital transfer by 20 percent, which supports my public goods story.