VictorJuiz/thesis huggingface dataset:
Model testing and analysis of interactions between tunnels in clay
Keywords: tunnelling

This dissertation describes a study of the interaction between closely spaced tunnels during shield tunnel construction, concentrating on the study of the short-term incremental behaviour of the liner. Carefully controlled physical model tests were carried out and the test results were complemented by a limited amount of numerical analysis. In the physical model tests described in this dissertation, two groups of tests were carried out at a laboratory scale; one set of tests studied closely spaced parallel tunnels and the other set investigated perpendicular tunnels. An important feature of the study was that a novel model tunnelling machine was designed and developed as part of the research. Thin steel tubes were used to model the tunnel linings. The experimental technique adopted in the preparation of clay samples (which is a well-established procedure) was found to produce high quality samples. Good repeatability was achieved in preparing the kaolin samples. The tunnelling machine allowed tunnel liners to be installed using similar procedures to those adopted in the construction of full scale shield tunnels using an earth pressure balance approach. The instrumentation system used in this experimental programme are shown to produce reliable data. During the model tests measurements were made of liner strains, pore water pressures and total stresses acting on the liner. Errors in the data logging system were shown to be very small (of the order of less than 2% of peak values). The mechanisms governing the structural interaction between closely spaced tunnels are highly complex. The tunnel installation was shown to modify the stresses acting on the liner of the adjacent tunnel. These stress increments led, in turn, to line deformations and induced bending moments. The nature of the interaction mechanisms depends on the geometric configuration of the tunnels, the liner properties, and overconsolidation ratio. For the parallel tunnels, the pillar width ratio (W/D) is an important parameter governing the magnitude of the interaction effects. the interaction effects increase as the pillar width ratio is reduced. Increasing the liner flexibility was found to reduce the induced bending moments but to increase the induced displacements. The interaction effects were larger in overconsolidated clay than normally consolidated clay. The worst case for interaction effects occurs when the pillar width is small, the liner is flexible and the value of OCR is large. Three-dimensional considerations suggest that interaction between parallel tunnels may be more severe than those measured in the corresponding perpendicular tunnel tests. However, the different nature of the mechanisms in the two cases appear to be more significant than this geometric effect.
Integration of rationale management with multi-criteria decision analysis, probabilistic forecasting and semantics: application to the UK energy sector
Keywords: semantics
probabilistic forecasting
energy and water
IBIS
energy ontology
decision ontology
MCDA
decision support systems

This thesis presents a new integrated tool and decision support framework to approach complex problems resulting from the interaction of many multi-criteria issues. The framework is embedded in an integrated tool called OUTDO (Oxford University Tool for Decision Organisation). OUTDO integrates Multi-Criteria Decision Analysis (MCDA), decision rationale management with a modified Issue-Based Information Systems (IBIS) representation, and probabilistic forecasting to effectively capture the essential reasons why decisions are made and to dynamically re-use the rationale. In doing so, it allows exploration of how changes in external parameters affect complicated and uncertain decision making processes in the present and in the future.
Once the decision maker constructs his or her own decision process, OUTDO checks if the decision process is consistent and coherent and looks for possible ways to improve it using three new semantic-based decision support approaches. For this reason, two ontologies (the Decision Ontology and the Energy Ontology) were integrated into OUTDO to provide it with these semantic capabilities. The Decision Ontology keeps a record of the decision rationale extracted from OUTDO and the Energy Ontology describes the energy generation domain, focusing on the water requirement in thermoelectric power plants.
A case study, with the objective of recommending electricity generation and steam condensation technologies for ten different regions in the UK, is used to verify OUTDO’s features and reach conclusions about the overall work.
Volcanic and magmatic processes at a young spreading centre in Afar, Ethiopia
Keywords: volcanology
Afar
tectonics
petrogenesis

The Dabbahu-Manda Hararo rift segment is a ~25 x 60 km rift zone in Afar, Ethiopia, where a series of axial dyke intrusions has recently occurred. Basaltic eruptions associated with individual dyking events between 2007-2010 have been fed from fissures along the rift axis and been relatively short-lived events lasting less than 60 hours. The volume of melt delivered to the rift surface by these eruptions has been a minor component of the total melt volume supplied to the shallow crust since the onset of the active rifting phase in 2005 and the current intruded to erupted melt ratio for the 2005-2010 period is ~260:1. This is below typical values for magmatic rift zones and may suggest that further volcanism is likely to occur before this activity ceases. 40Ar/39Ar geochronology of basaltic lavas from the flank of the rift and from a region of off-axis volcanism to the west of the rift zone gives ages of 25 – 450 ka. These constrain the development of a prominent axial graben in the northern part of the rift to < 30 ka and based on the age-distribution of lavas across the rift flank suggests that volcanism has been focused to the present neo-volcanic zone for at least 200 ka. Geochemical and isotopic constraints on melt generation suggest ~4-6 % partial melting of fertile mantle beneath rift at depth of ~100-75 km. Lavas erupted at the rift axis and from off-axis volcanoes are derived from a common mantle source, however, axial lavas are shown to represent slightly greater extents of partial melting suggesting a focused mantle melting anomaly, such as those seen at ocean ridges, is forming beneath the rift zone.
The effect of electoral institutions on party membership in central and east Europe
Keywords: Party Funding Regulation
Comparative Government
Electoral Institutions
Central and East Europe
Electoral Systems
Politics
Democratisation

Party membership levels in the new democracies of central and east European were predicted to remain universally low, stymied by post-communist legacies, the availability of state funding and the prevalence of mass media communications (van Biezen, 2003; Kopecký, 2007). However, more than two decades after the fall of the Berlin Wall, membership levels vary considerably between countries, and also between individual parties within party systems. Using freshly gathered party membership data, elite surveys and interviews, this thesis explores a number of institutional hypotheses to test whether, as in western democracies, electoral institutions influence how parties organise and campaign. This thesis finds that national electoral systems, municipal electoral rules and business funding regulations have an observable impact on how parties use their members. In particular, 'decentralised' electoral systems encourage greater involvement of members in voter contacting and other small campaign tasks. This thesis concludes that, contrary to the dominant literature, the availability of state funding has little impact on party membership recruitment. Instead, central and east European parties' attitudes to members are shaped by a complex interaction of institutional, cultural, ideological and strategic factors.
High density ammonia storage materials
Keywords: hydrogen storage
ammines
ammonia storage
ammoniates
borohydrides
ammonia

This Thesis considers the use of solid-state metal ammines as ammonia storage materials and endeavours to understand these materials on a fundamental chemical level. The ammines of LiBH₄, MgCl₂, MgBr₂, MgI₂ and Mg(BH₄)₂, are investigated. The structures of lithium borohydride ammines, Li(NH₃)nBH₄ with n = 1, 2, 3 and 4 are solved using X-ray and neutron diffraction, vibrational spectroscopy, nuclear magnetic resonance, and first-principles calculations. The reversibility, bonding and ammonia storage properties of this system are discussed, and investigated using gravimetric analysis and vibrational spectroscopy. The ammines of magnesium halides are investigated using X-ray and neutron powder diffraction, gravimetric techniques, nuclear magnetic resonance, first-principles calculations and vibrational spectroscopy. Their disordered structures, bonding, and decomposition are discussed, and the trends in their properties are used to interpret the properties of other ammines. The ammines of magnesium borohydride are investigated using X-ray and neutron powder diffraction, gravimetric techniques, first-principles calculations and vibrational spectroscopy. The structure, decomposition and reversibility of Mg(NH₃)₆(BH₄)₂ as an ammonia store are presented. Throughout the Thesis and at the end of each Chapter the possibility of using these ammines as solid-state ammonia stores is discussed.
Electrochemical properties of redox mediators at carbon electrodes
Keywords: cobalt phthalocyanine
cyclic voltammetry
quinone
carbon
nitrite
Marcus-Hush-Chidsey theory
sensing
potential distribution
modified electrode
electrochemistry

Chapter1 gives an overview of the basic principles of electrochemistry.
A rigorous electrochemical study on the solution phase and solid phase cobalt phthalocyanine (CoPC) is presented in chapter2. The formof CoPC on carbon electrodes was characterized by scanning electron microscope (SEM). The use of CoPC modified edge plane pyrolytic graphite (CoPC-EPPG) for sensing nitrite (NO₂⁻) was also investigated. It was found that the claimed mediator CoPC has no influence on the process. A bare glassy carbon (GC) electrode was successfully applied for the quantitative determination of nitrite as a simple alternative to the modified electrodes reported in the literature (chapter3).
Chapter4 compares the voltammetric responses of an edge plane pyrolytic graphite electrode covalently modifed with 2-anthraquinonyl groups (EPPG-AQ2) and solution phase anthraquinone monosulphonate (AQMS) in the presence of a limited concentration of protons. The solution phase and surface bound species show analogous responses resulting in split waves. Digisim™ simulation of the AQMS voltammetry have shown that the pH adjacent to the electrode may be altered by up to 5-6 pH units in low buffered solutions; this is caused by the consumption of protons during the electrochemical reaction.
Chapters5 and 6 compare the electrochemical properties of 2-anthraquinonyl groups covalently attached to an edge plane pyrolytic graphite (EPPG) and to a gold electrode. In both cases simulations using newly developedMarcus-Hush-Chidsey theory for a 2e⁻ process assuming a uniform surface did not achieve a good agreement between theory and experiment. Subsequently two models of surface inhomogeneity were investigated: a distribution of formal potentials, EӨ, and a distribution of electron tunneling distances, r₀. For both EPPG-AQ2 and Au-AQ2 modified electrodes the simulation involving EӨ distribution turned out to be the most adequate. This is the first time that Marcus-Hush-Chidsey theory has been applied to a 2e⁻ system.
Chapter7 briefly summarizes the obtained results.
Ordering transitions and localisation properties of frustrated systems
Keywords: frustration
phase transitions
localisation
critical phenomena

In this work we investigate themes related to many-body systems in which multiple ground states are accessible, a condition known as frustration. Frustration can arise in a number of contexts, and we consider the consequences of this situation with some examples from condensed-matter physics.
In some magnetic materials interactions between spins are such that no single spin configuration provides a unique ground state. In the class of frustrated magnets where the number of ground states is extensive, thermal fluctuations are strong even at temperatures significantly below the interaction strength. At such temperatures spins are highly correlated, and small perturbations may have profound consequences.
In this thesis we provide an example of this. By considering classical n-component spins with nearest-neigbour exchange on a frustrated octahedral lattice we show that – in the limit where exchange interactions are large – the system is in a disordered, correlated phase where correlations have the form of a dipole field. This is termed a Coulomb phase. From this phase we induce an ordering transition, lifting the degeneracy with weak, additional short-range interactions. By studying the transition in the solvable limit of n &rightarrow; ∞, we discover that the transition has identical thermodynamics to that of a magnetic system interacting through long-range, dipolar forces. Finally, we provide a more apposite characterisation of the transition, where the high-temperature side of the transition is described through the fluctuations of solenoidal fields, and the ordering corresponds to a condensation of these fields.
In a separate part of the thesis, we investigate the influence of disorder on frustrated lattices. We study a two-dimensional tight-binding model with nearest-neighbour hopping and on-site disorder. Restricting the allowed states to being those from the low-lying manifold of ground states, the disorder feeds through to act as effective disorder in the hopping terms, which decay algebraically with distance. The quasi-long range nature of this effective hopping leads to a situation in which the resultant single-particle eigenstates are critical, and we probe their behaviour numerically with a transfer matrix calculation.
The Aza-Bohlmann cyclisation and the synthesis of Pandanus alkaloids
Keywords: Furan
oxidative spirocyclisation
spiroaminal
spiroaminoacetal

Bohlmann et al. reported the oxidative spirocyclisation of 2-(ω-hydroxyalkyl)furans under Clauson-Kaas conditions to furnish 1,6-dioxaspiro[4.5]dec-3-enes, thereafter termed the “Bohlmann cyclisation.” This thesis describes the development of an analogous aza-Bohlmann cyclisation. Treatment of 2-(ω-aminoalkyl)furans with m-CPBA or singlet oxygen generates hydroxy- or methoxybutenolides, respectively, which undergo spirocyclisation upon treatment with H₂SO₄ to generate [4.4]- and [4.5]-spiroaminoacetals.
The axial/equatorial preferences of N-sulfonylspiroaminoacetals featuring a 3-O-isovaleryl or 3-O-benzyl substituent are described. Acid-catalysed equilibration revealed that in acetonitrile the axial isomer is thermodynamically favoured for both substrates.
The first total synthesis of the spiroaminoacetal alkaloid pandamarilactone-1 is discussed, via an aza-Bohlmann cyclisation, in 13 steps and 3% overall yield from 4-pentyn-1-ol.
Base excision repair of radiation-induced DNA damage in mammalian cells
Keywords: ionising radiation
Base excision repair
XRCC1
clustered DNA damage
FEN1

A specific feature of ionising radiation is the formation of clustered DNA damage, where two or more lesions form within one to two helical turns of the DNA induced by a single radiation track. The complexity of ionising radiation-induced DNA damage increases with increasing ionisation density and it has been shown that complex DNA damage has reduced efficiency of repairability. In mammalian cells, base excision repair (BER) is the predominant pathway for the repair of non-DSB clustered DNA lesions and is split into two sub-pathways known as short patch (SP) BER and long patch (LP) BER. SP-BER is the predominant pathway, especially in the repair of isolated DNA lesions. However, LP-BER is thought to play a greater role in the repair of radiation-induced clustered lesions. In this study, cell lines were generated stably expressing the fluorescently tagged BER proteins, XRCC1-YFP (marker for SP-BER) or FEN1-GFP (marker for LP-BER). The recruitment and loss of XRCC1-YFP and FEN1-GFP to sites of DNA damage induced by both ultrasoft X-ray (USX), a form of low linear energy transfer (LET) radiation, and near infrared (NIR) laser microbeam irradiation (‘mimic’ high LET radiation) was visualised in real-time and the decay kinetics of the fluorescently-tagged proteins determined. The half-life of fluorescence decay of FEN1-GFP following USX irradiation was longer than that of XRCC1-YFP, indicating that LP-BER is a slower process than SP-BER. Additionally, the fluorescence decay of XRCC1-YFP after NIR laser microbeam irradiation was fitted by bi-exponential decays with a fast component and a slow component, reflecting the involvement of XRCC1 in the repair of different types of DNA damage. In contrast to USX irradiation, where the XRCC1-YFP fluorescence decay reached background levels by 20 min, XRCC1-YFP still persisted at some of the NIR laser induced DNA damage sites even after 4 hours. This is consistent with the fact that the laser induces more complex damage that presents a major challenge to the repair proteins, persisting for much longer than the simple damage caused by low LET USX irradiation. Persistent, unrepaired DNA damage can potentially lead to mutations and replication-induced DSBs if it persists into S-phase. PARP1 inhibition reduced the recruitment of XRCC1 to DNA damage sites. However, a considerable amount of XRCC1 was still detected at the DNA damage sites, leading to the conclusion that there is a subset of DNA damage that requires XRCC1 but not PARP1 for repair. Understanding how clustered damage is repaired by the BER pathway can aid the design of future therapies which can be used in combination with radiotherapy to enhance the radiosensitisation effect. Knockdown of FEN1 was investigated and found to radiosensitise A549 (adenocarcinoma) cells, possibly as a result of an excess of unrepaired radiation-induced lesions requiring LP-BER for repair, although FEN1 knockdown alone induced cell death in non-cancerous BEAS-2B cells.
Thought, perception and the creative act: a study of the work of four contemporary French poets: Pierre Alferi, Valère Novarina, Anne Portugal and Christophe Tarkos
Keywords: language
poetry
contemporary
French
thought
creativity
perception

In this thesis I suggest that the work of the four contemporary poets studied manifests the vital role perceptual experience plays in the creation of literary texts. I engage primarily in the analysis of particular texts in order to argue for a shift in critical focus away from the explicit manipulation or exteriorization of the physical aspects of poetry (for example versification and explicit visual presentation) in order to concentrate on the role sensory aspects of thought play within it. Emphasis is therefore put on the way these poets draw from sensory experience, and the effect this has on the way their poetry functions. A shift away from traditional critical vocabulary is considered necessary in part due to the fact that discussions of the physical aspects of poetry often carry with them a variety of preconceptions concerning the nature of language, thought and the thinking subject. The tendency to pose dividing lines between mind and body, word and image, the physical and non-physical aspects of language has characterized the history of Western thought, and neither literature nor literary criticism have been exempt from the conceptual presuppositions inherent in such binary systems. Here, I consider how the work of Pierre Alferi, Valère Novarina, Anne Portugal and Christophe Tarkos transcends such dualisms, using the analysis of specific works to develop a critical approach that reflects their exploration of the ambiguity of the boundaries that separate different sorts of experience and means of expression. The thesis is therefore structured around the development of three concepts, ‘pensée-vue’, ‘pensée-voix’ and ‘pensée-toucher’, inspired directly by the texts studied, that are intended to indicate the vital role different forms of perception play in both the creation and experience of poetic texts. It is hoped that the development of an approach that emphasizes the connection between thought, perception and creativity will suggest the fertility of a shift in critical focus in domains beyond that of contemporary French poetry.
Identifying vital sign abnormality in acutely-ill patients
Keywords: Monitoring
Machine Learning
Patient
Data Fusion

The Emergency Department (ED) provides the first line of care for anyone seeking treatment for an urgent problem caused by an accident or illness . Physiological observations in the ED are a required part of patient care, and are used to monitor a patient's condition. Manual observations are recorded regularly by nursing staff, using a Track and Trigger (T&T;) system, in which higher scores indicate greater physiological abnormality.
An observational study at the John Radcliffe Hospital, Oxford, was conducted to assess the effectiveness of T&T; in the ED. Retrospective analysis showed that the effectivenessof T&T; was limited by poor completion, and incorrect calculation of T&T; scores. In response, we computed a retrospective, fully completed, scoring system which showedvery clear improvements in both sensitivity and specificity.
In addition to nurse observations, higher acuity ED patients have their vital signs continuously monitored by bedside monitors. However, the alerts generated by the monitors are routinely ignored due to their high false alert rate. We investigated whether a baseline data fusion model and two alternative techniques, weighted Parzen windows and Support Vector Machines, could identify events relating to vital sign abnormality while keeping the number of false alerts to a minimum. The performance of each model was assessed by calculating its sensitivity and specificity. However, it was not possible to select an optimal model, due to the difficulty in assessing the relative importance of maximising true alertsand minimising false alerts.
In the final part of this thesis, two limitations of the data fusion models are highlighted. Firstly, missing data is not handled coherently within the current models, and secondly the models do not make use of temporal information. One method of addressing both of these issues, Gaussian processes, was considered. Using this method, a novel framework was derived that allowed for alerts to be generated even when there is uncertainty in the vital sign values.