VictorJuiz/thesis huggingface dataset:
A Methodological Framework for Decision-theoretic Adaptation of Software Interaction and Assistance
Keywords: intelligent assistance
decision theory
software interaction
adaptive interfaces

In order to facilitate software interaction and increase user satisfaction, various research efforts have tackled the problem of software customization by modeling the user’s goals, skills, and preferences. In this thesis, we focus on run-time solutions for adapting various interface and interaction aspects of software. From an intelligent agent’s perspective, the system views this customization problem as a decision-theoretic planning problem under uncertainty about the user. We propose a methodological framework for developing intelligent software interaction and assistance. This framework has been instantiated in various case studies which are reviewed in the thesis. Through efforts of data collection experiments to learn model parameters, simulation experiments to assess system feasibility and adaptivity, and usability testing to assess user receptiveness, our case studies show that our approach can effectively carry out customizations according to different user preferences and adapt to changing preferences over time.
Transition Metal Catalysis: Construction of C–N and C–C bonds en route to Nitrogen Heterocycles, Chiral Esters and 6-deoxyerythronolide B
Keywords: transition metal catalysis
C–N and C–C bond formation
C–H bond fuctionalization
C–O bond activation
nitrogen heterocycles
carbonylation
total synthesis
6-deoxyerythronolide B

The Dong research group is interested in harnessing the power of transition metal catalysis to transform simple molecules and reagents (such as carbon monoxide, hydrogen gas, olefins, and C–H and C–O bonds) into valuable products (such as functionalized heterocycles, chiral carbonyl compounds and natural products). This thesis will describe our continual effort to achieve this goal. Part I describes the Pd-catalyzed functionalization of sp2 and sp3 C–H bonds. Carbon monoxide is used as a stoichiometric reductant in the cyclization of diarylnitroalkenes to afford biologically relevant 3-arylindoles and other N-containing heterocycles with carbon dioxide as the only stoichiometric byproduct. Also, an aryl sulfoxide moiety is shown to direct the arylation of sp3 C–H bonds to afford beta-functionalized amides. Part II describes the Ru-catalyzed sp3 C–O bond activation of alkoxypyridines and related heterocycles. In this transformation, an O- to N-alkyl migratory rearrangement occurs to afford N-alkylated pyridones which are structures found in many natural products and pharmaceutical agents. Part III describes our pursuit of metal-catalyzed asymmetric synthesis. Readily available benzylic bromides are carbonylated with carbon monoxide in alcoholic solvent mixtures. The resulting medicinally relevant 2-arylpropionic esters are obtained with moderate to good enantioselectivities. Preliminary results for the asymmetric hydrogenation of gem-diarylethylenes and novel ligand development are also disclosed. Part IV describes our efforts towards the total synthesis of 6-deoxyerythronolide B. Our retrosynthetic analysis of the macrolide antibiotic involves disconnections at the lactone linkage and between C7 and C8. The two equally complex fragments were prepared via reliable aldol, hydroboration, crotylation and redox chemistry. Rather than the typical macrolactonization method to form the 14-membered ring, we propose an alternative strategy where we plan to cyclize with a metal-catalyzed ring-closing metathesis event. Currently, this step is under investigation by other members in the group.
The Normativity of Nonstandard Emotions: An Essay on Poignancy and Sentimentality
Keywords: emotions
normativity
poignancy
sentimentality
nostalgia

This dissertation examines a particular quality of emotion experience that has received little attention in contemporary philosophical and psychological studies of the emotions. This is inversely proportional to the significant attention it receives in literature. I will refer to it as poignancy. Poignant emotions, such as nostalgia and the lyrical feelings pervasive in poetry, are emotions about time’s passage, or the fleetingness of things. My inquiry concerns the normative evaluation of such emotion experiences. Episodes of nostalgia and lyrical emotions are typically experienced as profound while they last, but they are also notoriously apt to be dismissed as sentimental, even by those who feel their pull. Sentimentality is a term of censure that exclusively targets emotions and emotionality; if an emotion is sentimental, then something about it is supposed to be false and wrong. But what are the merits of this charge against poignant emotions? When one has a nostalgic or lyrical emotion episode and reproaches oneself for being sentimental, who is correct—the person in the first moment, convinced by the emotion, or the person in the next, who doubts or retracts it? To adjudicate these disputes, we must turn to what I call the standard model of emotion evaluation that has emerged in the philosophy of emotions. This is a normative apparatus that enjoys wide consensus, but it has been built to evaluate the standard stock of examples in the literature, such as fear. Its application to nonstandard cases has not been undertaken. A major task of this dissertation is therefore to analyze poignant emotions in such a way that renders them evaluable on this model. However, once these analyses are in place, it turns out that the normative evaluation of poignant emotions yields surprising conclusions. In spite of their stigmatization, nostalgic aestheticizations of the past are much less vulnerable to the charge of sentimentality than commonly assumed. And lyrical feelings about the fleetingness of things are almost entirely immune to the charge, in a way that risks undermining our critical discourse about such emotion experiences.
Fighting Fires Together: Essays on Alliances among Fire Departments
Keywords: Strategy
Alliances

Organizations enter into strategic alliances for economic value that cannot be achieved by working alone. Despite the potential benefits many alliances fail to meet their goals, destroy value, and end in termination. Success within alliances is neither automatic nor assured. The ways that organizations arrange their alliances to contend with impediments to success is of great practical and theoretical importance. This thesis studies how formal and informal arrangements arise over time and influence the performance of U.S. fire departments. The first study empirically describes how formal contracting influences performance of the alliance and its members. I analyze a sample of responses by US fire departments to fires over 11 years, and I describe how contracting affects four dimensions of performance: arrival minutes, resolution minutes, property damage, and casualties. I find (i) the effect of contracts varies across qualitatively different outcomes, (ii) that contracts deliver separate costs and benefits at the level of the alliance and the organization, and (iii) that estimates are sensitive to matching on pre-contracting covariates including social context. The second study examines the role played by social context in contracting. Looking at the hazard of contracting between pairs of alliance partners I examine the effects of increased embeddedness in (i) focal relationships and in (ii) networks of outside relation- ships. I find that qualitative differences in prior interactions partly explain the decision to formally contract. I find that differences in arrangements with other partners affect formal contracting both directly and indirectly through interpretations of dyadic history. These findings suggest that models of relational mechanisms that accumulate within a relationship work both in parallel and interactively with broader social networks. The third study investigates how the design of alliances affects the performance of their members. I distinguish between (i) the extent to which departments rely on their own resources versus those of their alliance partners, (ii) the formality of arrangements, and (iii) performance in terms of property damage and casualties. I find that formal contracts are needed to improve some aspects of performance while informal arrangements are sufficient for others. This finding suggests a nuanced relationship among alliance structures and outcomes.
A Comparative Study of ELL and EL1 Narrative Competence During the Kindergarten Years
Keywords: narrative competence
English Language Learners
emergent literacy
vocabulary
story generation

Stories are complex linguistic constructions through which we share our interpretations of the social world. The ability to comprehend and produce stories is referred to as narrative competence. Narrative competence is rooted in social interactions in the preschool years that foster a sense of story structure and familiarity with story language. It has been shown to play a critical role in reading and writing achievement in the elementary school years since the language of literacy, like the language of storytelling, is predominantly decontextualized. The mastery of decontextualized language poses a significant challenge for children who enter kindergarten with little previous exposure to the majority language. The storytelling ability of these children was the focus of the present study. The study's primary aim was to examine second language narrative competence across the kindergarten years by comparing the fictional stories generated by a cross-section of EL1 and ELL junior and senior kindergarten children in response to a wordless picture book from the point of view of macrostructure (story structure), microstructure (story language), and the use of evaluative language. Grade and gender differences across and within language groups were also considered. A second aim of the study was to examine the relationship between narrative competence and receptive vocabulary and between narrative competence and print-based emergent reading skill. Overall, the results suggested that the ELL children's narratives were comparable to those of their EL1 counterparts with respect to most measures of microstructure, and with respect to macrostructure and evaluative language use. The one clear language-based difference favouring the EL1 children related to morpho-syntactic quality. Age-related differences were obtained on most measures and the results suggested parallel developmental trajectories across language groups. Gender was found to play a more prominent role in ELL than EL1 narrative performance. Few aspects of narrative were predicted by receptive vocabulary, suggesting dissociation between word- and discourse-level skills, particularly among the ELL children. On the other hand, emergent literacy scores predicted several aspects of microstructure, macrostructure and evaluative language use. The study provides evidence that various aspects of narrative competence might be differentially related to vocabulary and emergent literacy skills in ELL and EL1 kindergarten children.
The Sequence and Function Relationship of Elastin: How Repetitive Sequences can Influence the Physical Properties of Elastin
Keywords: Elastin
Bioinformatics
Low complexity sequence
Biomaterial

Elastin is an essential extracellular protein that is a key component of elastic fibres, providing elasticity to cardiac, dermal, and arterial tissues. During the development of the human cardiovascular system, elastin self-assembles before being integrated into fibres, undergoing no significant turnover during the human lifetime. Abnormalities in elastin can adversely affect its self-assembly, and may lead to malformed elastic fibres. Due to the longevity required of these fibres, even minor abnormalities may have a large cumulative effect over the course of a lifetime, leading to late-onset vascular diseases. This thesis project has identified important, over-represented repetitive elements in elastin which are believed to be important for the self-assembly and elastomeric properties of elastin. Initial studies of single nucleotide polymorphisms (SNPs) from the HapMap project and dbSNP resulted in a set of genetic variation sites in the elastin gene. Based on these studies, glycine to serine and lysine to arginine substitutions were introduced in elastin-like polypeptides. The self-assembly properties of the resulting elastin-like polypeptides were observed under microscope and measured using absorbance at 440nm. Assembled polypeptides were also cross-linked to form thin membranes whose mechanical and physical properties were measured and compared. These mutations resulted in markedly different behavior than wild-type elastin-like proteins, suggesting that mutations in the repetitive elements of the elastin sequence can lead to adverse changes in the physical and functional properties of the resulting protein. Using next-generation sequencing, patients with thoracic aortic aneurysms are being genotyped to discover polymorphisms which may adversely affect the self-assembly properties of elastin, providing a link between genetic variation in elastin and cardiovascular disease.
Reading, Writing and Pedagogy: The Impact of Ontario Education Faculties' P/J Programs on Graduates' Knowledge and Ability to Teach
Keywords: elementary
literacy
education
preservice
faculty
reading
writing
teaching
pedagogy
content

The purpose of this study was to determine the impact of Ontario’s Primary/Junior teacher preparation programs on graduates’ knowledge and ability to apply what they know about literacy education. The research examined the content of the programs, the extent to which this content reflected evidence-based components of literacy instruction, and the degree of variability across programs. A range of strategies including self-reporting by graduates, interviews, and reviews of course materials (e.g., course outlines, course topic schedules, reading lists) were used to examine the breadth and depth of what was covered in the required literacy courses. A proportional sample of 210 graduates representing all nine English-speaking faculties of education in Ontario completed surveys and submitted course materials. Twenty-nine of these also participated in in-depth interviews. Interviewees were asked to reflect upon their understanding and ability to apply what they had learned, as well as to offer their impressions of their programs and to discuss their personal feelings of preparedness to teach literacy. Quantitative and qualitative research methods were used to describe and summarize findings. Process/Outcome Matrices revealed various themes. In summary, faculty literacy programs varied greatly with respect to both length and content. Course materials and descriptions from graduates also suggested that variability across sections within programs was as great as that across programs. Although courses covered theories of child development they generally lacked a theoretical framework for literacy instruction. Moreover, many respondents reported learning little about how to teach reading and writing. Such responses were more prevalent in certain programs. Many graduates believed that explicit instruction is a necessary component of “good” literacy teaching, however, most graduates were not able to demonstrate an understanding of the complexities of language and literacy, and many could not describe how to implement effective literacy instruction, or to address the diverse needs of students. Recommendations include: lengthening the required faculty literacy courses in order to provide more breadth and depth of coverage; refining the manner in which instruction in literacy education is provided at faculties; increasing the vigilance with which governing bodies oversee faculty literacy course content; and improving practicum placement experiences.
Disruption of Giant Molecular Clouds by Massive Star Clusters
Keywords: Star formation
Interstellar Medium

The lifetime of a Giant Molecular Cloud (GMC) and the total mass of stars that form within it are crucial to the understanding of star formation rates across a whole galaxy. In particular, the stars within a GMC may dictate its disruption and the quenching of further star formation. Indeed, observations show that the Milky Way contains GMCs with extensive expanding bubbles while the most massive stars are still alive. Simulating entire GMCs is challenging, due to the large variety of physics that needs to be included, and the computational power required to accurately simulate a GMC over tens of millions of years. Using the radiative-magneto-hydrodynamic code Enzo, I have run many simulations of GMCs. I obtain robust results for the fraction of gas converted into stars and the lifetimes of the GMCs: (A) In simulations with no stellar outputs (or ``feedback''), clusters form at a rate of 30% of GMC mass per free fall time; the GMCs were not disrupted but contained forming stars. (B) Including ionization gas pressure or radiation pressure into the simulations, both separately and together, the star formation was quenched at between 5% and 21% of the original GMC mass. The clouds were fully disrupted within two dynamical times after the first cluster formed. The radiation pressure contributed the most to the disruption of the GMC and fully quenched star formation even without ionization. (C) Simulations that included supernovae showed that they are not dynamically important to GMC disruption and have only minor effects on subsequent star formation. (D) The inclusion of a few micro Gauss magnetic field across the cloud slightly reduced the star formation rate but accelerated GMC disruption by reducing bubble shell disruption and leaking. These simulations show that new born stars quench further star formation and completely disrupt the parent GMC. The low star formation rate and the short lifetimes of GMCs shown here can explain the low star formation rate across the whole galaxy.
Development and Testing of a Nurse Practitioner Secondary Prevention Intervention for Patients after Acute Myocardial Infarction
Keywords: secondary prevention
acute myocardial infarction
nurse practitioner
cardiac prevention
cardiac rehabilitation
adherence
quality improvement

Patients with acute myocardial infarction (AMI) are at high risk for reinfarction and death, with the highest rate of death and reinfarction occurring within 30 days of AMI. Therapies that have been shown to reduce these risks (secondary prevention) continue to be underutilized. Nurse practitioners are well positioned to provide secondary prevention during and following hospitalization. The purpose of this pilot study was to examine the feasibility, acceptability, and preliminary effects of an NP delivered secondary prevention intervention. The specific objectives were: 1) to describe NP activities when delivering the secondary prevention intervention; 2) to evaluate the effect of the NP intervention on the rate of implementation of evidence-based secondary prevention treatment strategies and the patients’ achievement of secondary prevention target goals; and, 3) to examine the relationship between the NP activities delivering the intervention and secondary prevention goal achievement by patients. A prospective cohort design was used, in which patients’ achievement of target goals were compared between patients who received secondary prevention care from an NP and those who received usual care. The sample of convenience consisted of 65 patients with AMI. Data on practice activities and implementation of secondary prevention by the NP were collected before discharge from hospital and one week, two weeks, six weeks and 3 months after discharge. Data on patients’ achievement of goals were obtained before discharge from hospital and 3 months after discharge from both groups. This study’s results provide preliminary evidence that an NP delivered secondary prevention intervention, beginning prior to discharge and continuing for three months post myocardial infarction, significantly improves the implementation and uptake of guideline based secondary prevention treatments and risk factor reduction strategies. NP-led interventions such as this warrant replication. The unique contribution of the NP with this patient population is the training and skills needed to deliver all aspects of secondary prevention, including pharmacological and nonpharmacological therapies, without the immediate availability of a physician.
Why Teachers Trust School Leaders
Keywords: trust
leadership
teachers
leaders

Research indicates trust in schools significantly relates to student achievement and trust in school leaders significantly relates to trust in schools. This study expands on the existing research by identifying behaviours principals display and teachers identify that correspond to antecedent conditions of trust, as identified in the research literature. Principalunderstandings are compared to teacher articulated thoughts in order to identify if shared understandings and interpretations of events are a component of trust in schools. Seventeen survey questions about trust were asked in 138 schools. Three high trust and three low trust schools were identified via deviation from the grand mean. Interview data related to a broad spectrum of school structures and daily events was gathered at the six identified schools from a randomly selected group of teachers and each school’s principal. The interview data was coded using antecedent conditions of trust as the organizational units for analysis. Supporting previous research, this thesis finds teacher data identified the antecedent conditions that are described most frequently by teachers as being Competence, Consistency and Reliability,Openness and Respect. Principal data identified the antecedent conditions of trust as being similar, not identical. There are relevant differences described in elements within the antecedents between teachers and school leaders. Overall, the results confirm the findings of Bryk and Schneider and Tschannen-Moran, while adding detail to the understanding of what matters in trust when in-school educators reflect on issues of organizational life.
Effects of Silicon Variation on Nano-scale Solid-state Memories
Keywords: SRAM
MRAM
STT-MRAM
Silicon Variation

This thesis explores means of mitigating the effects of silicon variation on SRAM by means of circuit techniques. This thesis also explores novel read and write techniques for MRAM that support a non-destructive read operation and power-saving write operations in the face of device and silicon variation. First, this thesis proposes the use of a cross-coupled bit line BL biasing scheme that retains an SRAM's fast access speed while reducing the read-access failures in the presence of Vt variation, without excessively increasing the SRAM cell size. It is shown, by extensive Monte-Carlo simulations using 22-nm predictive CMOS models, that the proposed scheme reduces the cell area by 6.5% compared to the conventional BL biasing schemes also analyzed. Second, this thesis proposes a 10T SRAM cell that supports lower voltage operation, achieves lower static power dissipation, and is similar in area to the 6T SRAM cell when the 3-sigma variation of Vt exceeds 40% of nominal Vt. The 10T cell achieves improved write functionality, in comparison to the 6T cell, by preemptively turning off the cell's power supply to the side of the cell that is being pulled low, while not disturbing any unselected cells. Write access time is not affected, as the positive-feedback required to quickly regenerate CMOS voltage levels remains intact. Finally, this thesis proposes a negative-resistance read scheme and write scheme for spin-torque-transfer (STT) MRAM. A negative resistance shunting an STT-MRAM cell guarantees a non-destructive read operation, and saves power during write operations compared with a conventional scheme. Measurements confirm an 7ns non-destructive read access time without the use of a typical sense amplifier and an average write power savings of 10.5% for a 16Kb STT-MRAM fabricated in 0.13um CMOS using a CoFeB/MgO/CoFeB MTJ.