VictorJuiz/thesis huggingface dataset:
Embedded, Embodied, Envoiced: Contextualizing Complaint in Spenser, Shakespeare, and Mary Wroth
Keywords: complaint
melancholy
monologue
poetry
romance

This thesis investigates the complex interaction between early modern complaint and genres in which it embeds, including epic allegory, tragedy and prose romance. Most criticism treats the complaint as free-standing, but the interactions between genres provide insight into how complaint represents interior, affective experience that remains vitally interrelated with its environment. The Ovidian legacy of Heroides and Metamorphoses enables a complainant to create an inner, affective landscape that has a topographical counterpart in the narrative and engages the sympathy of an audience. The interaction between body and landscape is not just figurative: as the complainant speaks his/her voice resonates in the world, and the breath, tears and blood that the body produces imbue the landscape with affect. The complainant’s body is thus doubly embedded in the environment of the narrative and the genre in which the complaint interacts. Transactions on both levels situate complaint within its historical and cultural contexts, and contribute to its function as an integral part of a literary whole. In The Ruines of Time and Book II of The Faerie Queene, Edmund Spenser presents phenomenological challenges that explore the audiences’ vulnerability to spectacular emotional persuasions. Complaint is doubly inscribed as a scene of the futility of speech and of rhetorical success – a scene that William Shakespeare’s Titus Andronicus populates with legitimate attempts to inspire a change of heart that are met with overwhelming human violence, ultimately turning complaint into a weapon that reifies hegemonic power. In Countess of Montgomery’s Urania, Lady Mary Wroth’s complaints are both embodied and envoiced, positing important connections between speaking, the speaker’s aural experience of her own voice, and the ability to sympathize with others. All three of these authors activate complaint’s intertextual and generically diverse history each time a speaker uses the form, evoking meaningful expectations for this famously elastic genre.
The First Dynasty of the Sealand in History and Tradition
Keywords: Babylonia
First Sealand Dynasty
Middle Babylonian Period
Paleo-Babylonian Period
Second Millennium Mesopotamia

In the latter half of the eighteenth century B.C.E. (in the Middle Chronology), the southernmost regions of Mesopotamia started rebelling against Babylonian royal power, merely one generation after Hammurapi of Babylon had unified the land in annexing the small kingdoms that had emerged at the beginning of the millennium. This rebellion eventually resulted in the formation of a poorly documented kingdom, the Sealand, which would last as an independent state for over two centuries, maintaining itself long after the Amorite dynasty of Babylon fell. Because of the dire lack of sources, this entire period has remained for us largely in the dark, historically and culturally. Late Old Babylonian royal inscriptions are few and the year names become less evocative of political events, early Kassite evidence is even scarcer, and until recently Sealand I sources were near to non-existent. Our incomplete understanding of pottery sequences and the apparent abandonment of several urban centres in southern Babylonia in that period have made and kept this dynasty very elusive. Until now it was known to us almost exclusively through its inclusion into later king lists and chronicles. The publication in 2009 of well over four hundred archival texts bearing date formulae of Sealand I rulers, soon to be followed by a few literary and divinatory texts, finally made it possible to start filling this hiatus. This dissertation proposes a history of the Sealand I kingdom, based on this new evidence and on a reevaluation of the previously known sources. The aspects examined are: the recording and transmission of knowledge on the Sealand I dynasty in Mesopotamian historiography; the political history, including a discussion of the geography and the relative chronology; the panthea and the palace-sponsored cult, which show how the Sealand I kings positioned their rule in a Larsean tradition, but with supra-regional ambitions; the economy â mainly the palatial administration and transformation of agricultural and animal resources, which also reveal a very specific model of institutional integration between the palace and temples.
Hysteria: Potential Dramaturgies Toward a Portrait of Ambiguity
Keywords: Charcot
Ethics of Representation
Hysteria
Modernity
Performance
Trauma

This work asks the question, primarily: what kind of performance is the hysterical attack? And what is the nature of hysteria in and as performance, as it occurred at the Salpêtrière in the nineteenth-century? The Salpêtrière hysteria project was a medical one, but also a theatrical one. The hysteric’s public appearance was a continual ethical provocation, pointing not only to the vulnerability of her person, but the unstable position of her spectator. The hysteric points to the fraught and exciting nature of theatrical representation, continually drawing out dilemmas and unexpected dynamics of witnessing the suffering of others. In the Salpêtrière documents, the gravity of institutional violence committed against female patients at the level of representation is undeniable. This thesis works to express the overt and subtle damages done to hysterical women in Charcot’s hospital: public and private bodily harm, sexual violation, dismissal, objectification, use, exposure, reduction. Simultaneously, the chapters seek to draw attention to the hysteric’s resistance to these phenomena. So often, it is simply by being herself that the hysteric points to the inherent weaknesses in these systemic modes of violence. Photographers were forced to new levels of technical innovation and flexibility in order to capture the hysteric’s fiercely mobile body. Terminology spun out an anxious series of words to try to negotiate her dynamism. The excessive exposure of her emotional, intellectual and sexual life in the Iconographie and on stage, framed by equally excessive empirical constraints, under scrutiny, ultimately reveals the uncontainable remainder of the hysteric’s personhood that slips from view, bringing the inadequacy of positivist and misogynist spectacle into relief. Charcot created a unique mixture of drama and science in his transmission of his findings about hysteria. The hysteric made the medium express beyond expectation.
Investigating Mediators of Endothelial Dysfunction as Potential Therapeutic Targets in Severe Malaria
Keywords: Cerebral malaria
GSNOR
Heme
Hemopexin
Nitric Oxide
S-nitrosylation

Malaria remains a leading cause of global childhood morbidity and mortality. The use of artemisinin-based antimalarials has improved outcomes from severe disease but mortality rates remain high. Adjunctive interventions that target deleterious host responses to infection may improve outcomes beyond that of antimalarials alone. The pathogenesis of severe malaria is incompletely understood; however, endothelial dysfunction is thought to play a critical role in disease severity and outcome. Our overarching hypothesis is that a detailed understanding of mediators regulating malaria-induced endothelial dysfunction, specifically free heme and NO bioavailability, will identify novel therapeutic targets to improve clinical outcomes. Here we show in two independent studies, that Ugandan children presenting with severe malaria have elevated levels of free heme, released during hemolysis, and decreased levels of a protective host protein, hemopexin. Furthermore, ratios of heme:hemopexin are associated with adverse clinical outcomes, including metabolic acidosis, severe anemia, acute kidney injury, and long term mortality. In a preclinical model, the deletion of hemopexin results in increased susceptibility to malaria supporting a mechanistic role for hemopexin in mediating protection from severe disease. In contrast to free heme, nitric oxide (NO) promotes endothelial stability. Increasing NO bioavailability, as induced by deletion of the s-nitrosoglutathione reductase (GSNOR), is associated with improved survival and neurological function in experimental cerebral malaria. Improved outcomes were associated with reduced recruitment of CD4+ and CD8+ T cells into the brain, and increased circulating levels of Angiopoietin-1 associated with preserved endothelial and blood brain barrier integrity. In summary, these data implicate heme and GSNOR in contributing to the pathogenesis of severe malaria, and suggest that interventions that disrupt the toxic effects of these two pathways may improve outcomes from severe and fatal malaria when used in conjunction with antimalarials.
From Conflicts of Sovereignty to Relationships: Recovering Nineteenth Century Relational Internationalist Perspectives in Private International Law
Keywords: Legal History
Private International Law
Public International Law

This thesis seeks to demonstrate that contrary to conventional histories of the discipline, 19th century writings on Private International Law included an internationalist strand that focused on the individual, rather than the state, but adopted an account of the individual as social and relationally constituted. The thesis dispels two common assumptions about the 19th century intellectual history of the field: first, that all individual - and private law – centered perspectives were overly liberal and individualistic and second, that the association between Public and Private International Law enabled the latter to focus on global public goods and global justice generally. By contrast, the thesis shows, on the one hand, that many 19th century theories focused on the relationship between Public and Private International Law injected much of the formalism and alleged neutrality of today’s Private International Law and on the other, that several individual-centered perspectives adopted a relational, rather than individualistic image of the individual. By recovering academic debates in Private International Law between the mid 19th to the mid 20th century, the thesis traces how this “relational internationalist” perspective was misunderstood and eventually disappeared from the memory of the field. Through a detailed analysis of the writings of the three main protagonists of the “relational internationalist” perspective, namely Joseph Story, Carl von Savigny, and Josephus Jitta, the thesis recovers the analytical foundation of this lost theoretical perspective with respect to rights, legitimate authority and the cosmopolitan dimensions of Private International Law. This thesis both tells a different history of 19th century Private International Law than the conventional one, and suggests that its “relational internationalist” component could provide a platform on which to now build a humanist perspective in PrIL which focuses both on the recognition, as well as the social responsibility of individuals in their transnational relationships.
"I may act till the world grows wild and tense": The Performances of E. Pauline Johnson Tekahionwake
Keywords: Canadian theatre history
Indigenous performance
Pauline Johnson
Tekahionwake

This dissertation documents and analyzes the performance history of Mohawk (Kanien’kehá:ka)-English poet and performer E. Pauline Johnson Tekahionwake. She was born in 1861 on the Six Nations Reserve of white and Mohawk parentage. By 1892, Johnson had developed a professional career as a travelling actress. Until her breast cancer diagnosis in 1909, she performed across Canada, the United States, and Great Britain. While on tour she recited her poetry, enacted adaptations of her prose stories, dressed up in fancy costumes, and performed comedic sketches (often in character-based dialect) with various acting partners. Although her performance history is intriguing, most scholarship about Johnson concentrates on the immense impact that her poetry had on the development of Canadian culture and mythology. However, this doctoral study explores the reasons that Johnson’s performances were largely overlooked in critical assessments of her impact. I propose a new set of paradigms and methodological tools to account for very divergent assessments (both appreciative and critical) of this important Indigenous performer by engaging with evocative fragments of Johnson’s archive. To this end, I explore the mutable and transformative quality of Johnson’s theatre history, mostly in chronological format. In addition, I address the substantial sophistication of her strategies and approaches, and the difficulties that she encountered as an Indigenous woman performing to settler audiences, within a framework of specific economies of representation. My examination of Johnson’s theatre history begins with a micro-historical focus on Johnson’s performances of 1892, when she was developing her theatrical skill set and arriving at a set of conventions on which she would rely during her touring life. Next, my dissertation discusses the variations of Johnson’s performances—the constant revision of her persona through both costuming and repertoire. Finally, I offer a detailed analysis of the dramatic repertoire that Johnson enacted in her later years. I draw on a plethora of primary research artifacts (clippings, reviews, performance photos, and scripts related to Johnson’s performance history) and glean significant historical information from these sources through a careful study of theatrical cultures active in the late nineteenth century. This allows for an exploration of the biases that underpin many responses to Johnson’s theatrical history – biases that are, so often, attached to broader critical engagements with Indigenous performance histories.
La fiction littéraire brève haïtienne, entre oraliture kreyòl et écriture française
Keywords: Creole
French
Haiti
Literature
Orality
Short story / lodyans

Dès son émergence dans les périodiques locaux du début du XIXe siècle, la fiction littéraire brève haïtienne d’expression française s’inscrit d’emblée dans une tradition réaliste foncièrement nationaliste qui relève d’un fort souci d’altérité exprimé dans ses sujets ainsi que dans ses caractéristiques formelles, discursives et linguistiques. Ce décentrement littéraire initié par Ignace Nau à travers une prose fictionnelle, qui mise sur l’exploitation de l’oraliture kreyòl visant une écriture haïtienne d’expression française originale, s’avère être la base sur laquelle repose ce que la critique appelle unanimement le « véritable roman haïtien ». Plusieurs auteurs de prose fictionnelle des générations postérieures ont perpétué cette tradition de décentrement, dont tous les éléments se trouvent magistralement cristallisés dans les lodyans littéraires de Justin Lhérisson. Parmi les écrivains-lodyansè haïtiens contemporains, Gary Victor est celui qui a le plus profité de l’héritage littéraire de Nau et de Lhérisson. En raison de son caractère polyphonique et du rire subversif qu’elle suscite, l’œuvre à la fois traditionnelle et postmoderne de Victor, renouvelle le lodyans en y intégrant du fantastique et du réalisme merveilleux, ce qui permet à l’auteur de rendre compte de manière intéressante de la présence de la magie dans la vie sociale, politique et dans l’inconscient collectif du peuple haïtien. Pour confirmer ces hypothèses, nous avons établi un corpus composé de 51 fictions brèves couvrant les principales périodes littéraires haïtiennes. Les œuvres du corpus sont passées au crible d’une analyse méthodique basée sur une approche mixte, s’inscrivant à la fois dans une perspective narratologique et poststructuraliste, qui tient compte de la complexité linguistique du genre narratif bref dans le contexte haïtien dit « franco-créolophone ». Cette étude sur l’évolution historique et théorique de la fiction brève haïtienne répond à certaines questions essentielles au nécessaire renouvellement des études littéraires haïtiennes. Après une remise en cause systématique de la vision ethnocentrique étriquée responsable de la réception négative des œuvres littéraires haïtiennes du XIXe siècle, nous procédons à une analyse détaillée du corpus pour aboutir à une nouvelle tentative de théorisation du lodyans littéraire basée sur un ensemble de critères à la fois formels, discursifs, pragmatiques et linguistiques.
Impact of Maternal Inflammatory Conditions on the Expression of Drug Transporters
Keywords: Drug Transporters
Maternal Inflammation
Pharmacokinetics

Inflammation-mediated changes in drug disposition commonly involve alterations in the expression of drug transporters and drug metabolizing enzymes. Placental drug transporters including ABC and SLC drug transporters are major determinants of fetal drug exposure. We hypothesized that inflammatory conditions during pregnancy would impact fetal drug exposure through alterations in placental transporter expression. Two inflammatory conditions were examined as part of this thesis, HIV infection and obesity. In a series of in vivo studies, pregnant HIV-Transgenic rats (HIV-Tg) as well as pregnant wild-type rats were administered bacterial endotoxin to model the presence of endotoxemia in HIV patients. Endotoxin administration significantly downregulated numerous placental and hepatic drug transporters in both HIV-Tg and WT rats. In addition, the presence of the HIV transgene along with bacterial endotoxin further downregulated the expression of placental P-gp, OATP2B1 and Slco4a1 than was detected with either inflammatory condition alone. This was attributed to an augmented inflammatory response to endotoxin in HIV-Tg rats. Overall the findings of these studies will aid in better predicting drug-disease interactions. As many ART are highly influenced by transporter mediated processes, this will assist in optimizing maternal treatment as well as minimizing vertical transmission and/or fetal toxicity. A second inflammatory condition investigated in this thesis is maternal obesity; which is a low-grade chronic inflammatory condition. However, in an in vivo model of maternal obesity, obesity was neither associated with a measurable inflammatory response, nor was it associated with significant changes in drug transporter expression.
Conceptualizing the State-nation via Education Reform: From Multicultural to Intercultural Citizenship
Keywords: Alternate Globalization
Alternate Pedagogies
Citizenship
Democracy
Education For All
India

Transnational movements of sociopolitical culture defy the integrity of the nation-state. Its organizational principle of singularity, and struggles to accommodate increasing diversity within homogeneity, are challenged by the increasing prominence of alternate and multiple ways of being and knowing. Nation-state education systems organized to deliver citizenship values, fail to rectify the fracture between their quest for multicultural participation and their promotion of conformity within a single ‘national’ identity. Systems of education are products of their respective sociopolitical systems. Hence, notions of citizenship (inclusion) and democracy (participation) must be reformed to facilitate genuine education reform. The nation-state is a sociopolitical project that confines pedagogical reform within the framework of a paradigm. Education reform can only be achieved by substituting the concept of multi-cultural, with inter-cultural citizenship, thereby transforming the unidimensional nation-state into a pluralist state-nation. The state-nation is an ideal-type conceptual framework which is predicated upon a constant (re-)negotiation of categories and their corresponding belonging-identities, so that all boundaries remain liminal and permeable rather than immutable and exclusionary. India has witnessed the longest sustained attempt at education reform, as well as the largest in size and scope, by any national government, international organization or non-government organization. This dissertation examines the participation of statist, civil society and multi-national participants, within the context of education reform in India. It also explores the capacity of the state-nation model of education reform to contribute to an Indian education diplomacy that could influence global Education For All (EFA). Intercultural citizenship as the root of the state-nation, has the potential to become an avenue for South-South dialogue and a means to create alternate notions of ‘modernity’, ‘development’, and ‘globalization’. De-linking education from the nation-state and viewing it in relation to the state-nation, makes possible a profound and far reaching ‘reform’ of ‘education’ from a social justice perspective.
Investigation of Cell Nucleation and Growth in Foam Injection Molding through Visualization
Keywords: Conductive Polymer Composite
Foam Injection Molding
Gas-Counter Pressure
High-Pressure Foam Injection Molding
In-situ Mold Visualization
Mold-opening

Foam injection molding (FIM) is one of the most promising manufacturing methods for thermoplastics, owing to its capability to produce low-density and lightweight products with high dimensional precision at fast manufacturing rates. However, achievement of a uniform fine cell structure is very challenging in this technology. The issue arises from the lack of clear understanding of cell formation mechanisms and complicated bubbles’ dynamics in FIM. Here I employed an in-situ mold visualization technique to closely and continuously monitor foaming phenomena, occurring inside the mold and during injection, in order to uncover underlying mechanisms of cell nucleation and growth in FIM. In this context, an innovative visualization mold is designed and manufactured. Using the visualization mold, I first studied cell nucleation and growth mechanisms in high-pressure FIM, and proposed the strategy of using a melt packing pressure to remove the nucleated cells during mold filling and switch nucleation mechanism from “gate-nucleation” to “shrinkage-induced” nucleation. Then, the application of a gas-counter pressure (GCP) with FIM, and cell nucleation mechanisms in this technology, was thoroughly explored. The investigation on cell nucleation and growth mechanisms was then extended to high-pressure FIM technology followed by precise mold-opening (or high expansion FIM). Inasmuch as composite thermoplastics foams comprise a large percentage of FIM parts, I extended this research to a comprehensive study on the mutual interaction of nucleated cells and carbon fibers dispersed in a polystyrene matrix in high-pressure FIM. The latter was successfully done using the designed visualization mold and the proposed high-pressure FIM protocol.
The Influence of Spatial Heterogeneity of Prey on Predator Growth and Energetics
Keywords: Aquatic Ecology
Food Web
Foraging
Predator-Prey Interactions
Zooplankton
Zooplankton Bioenergetics

Ecosystems are inherently heterogeneous, with organisms distributed in an uneven manner due to physical and biological forces. Animals have evolved to exploit the â patchinessâ of prey items to increase food consumption, yet the energetics associated with foraging in a patchy environment, along with the relationship between prey patches and consumer growth, is not fully understood. To investigate how the patchiness of food influences consumer consumption and growth I devised a series of experiments utilizing the common freshwater cladoceran