Well, when we do talk about Quebec, the first thing that strikes our mind the high number of individuals that are migrating to Quebec. There is no doubt it must be because of the calmness
Well, when we do talk about Quebec, the first thing that strikes our mind the high number of individuals that are migrating to Quebec. There is no doubt it must be because of the calmness and the silent and happy environment that you find there. However, immigration to Quebec isn’t that easy and involves a great deal of legal formalities that must be dealt with ease and in a proper manner. Many do even look out to find the Quebec Skilled Worker Visa but they fail to get it. Thus, we have brought forward you the opportunity to get it without much issue. The work needed to deal by you is giving us all the required documents and your full faith on us. Nile Immigration will handle the rest of the matters that aren’t easy for a common man.
Well, if you are moving to Quebec, you should know of the fact about it. For your help, we have mentioned some of the greatest things that you must know about Quebec.
Quebec is a part of Canada and comes under the list of thirteen Provinces and territories of Canada. It can be said to be a island as it is well surrounded by Bay throughout. To the West, it is bordered by the province of Ontario and waterbodies of Hudson Bay and James Bay. To the east of this province, we can find the Gulf of Saint Lawrence and the beautiful Newfoundland and Labrador. Well, the greatest of all fact is that Quebec is the largest province by area that Canada ever had and specially second largest administrative division. Along with Ontario, historically, this province is considered to be the part of Central Canada.
More about Quebec
Quebec is no doubtedly the most populated province of Canada after Ontario in the list. In Canada, it is quite difficult to find a whole population speaking in French but with the time, Quebec got involved much more in speaking French. In fact, French is the sole provincial official language of Quebec which is definitely a boast for the French speaking population. You will even find English speaking population and they are mostly found towards the west of the island of Montreal but majority of them can be found in Outaouais, Eastern Townships, and Gaspe regions.
Speaking of the Quebec Skilled Worker Immigration Processing Time is not more than 13 months. Hardly does it take more than 3 months when there are certain problems with the documents required otherwise once the required fund is provided the immigrant can immigrate to Quebec without facing any issue. However, even if any of the minimum requirements hasn’t been met then the immigration may be cancelled. Same happens with the restriction opposed by the province, if anyone violate the restriction they immigration will be terminated after proper procedure conducted. However, with the help of Nile Immigration, you won’t have to face any of the following. So, its time to cheer up.


Many patients who suffer from chronic symptoms have had the experience of going to the doctor, getting diagnostic tests, and then being told, “all the tests are normal”.
How can this be? How can someone feel so poorly, yet have normal tests?
Here is the main reason. Almost every test and diagnostic procedure in conventional medicine is focused on uncovering a disease. In other words, the tests and procedures are looking for pathology. They are looking for something that is broken. They are looking for something that will show evidence of organ or structural damage. They are also looking for markers that indicate a “disease”.
For example, a blood test can show a high sugar level, elevated cholesterol, or a poorly functioning kidney. A cardiac catheterization can reveal a blocked artery, a bone density scan will see if you have osteoporosis.
However, none of these tests will show why you have these problems, and certainly none of these tests will be abnormal until you actually have a pathological condition (a disease).
Functional tests, on the hand are looking for imbalances in physiology, biochemistry, energy, and anatomy and, of course functionality.
Functional tests can detect imbalances that can lead to disease. These imbalances may precede true pathological (disease) manifestations by years or decades. By addressing (correcting) these imbalances early enough, wellness can be restored and overt disease prevented.
Here are some examples of some functional tests:
A comprehensive digestive stool analysis (CDSA)- this is a battery of tests which measure chemicals in a stool sample. This test can detect species of bacteria and fungus, digestive enzyme levels, PH, absorption of fat, digestion of protein and several other parameters.
Serum homocysteine levels- homocysteineis a toxic amino acid that becomes elevated when B vitamin function is suboptimal. Elevated homocysteine is a surrogate marker for lack of available methyl groups in the system. These methyl groups are normally utilized to produce neurotransmitters, detoxify tissues, and serve as anti-oxidants and a long list of other functions. When methyl groups are depleted (and homocysteine is elevated) diseases such as coronary artery disease, birth defects, diabetes, high blood pressure, cancer, kidney problems and many others can result.
Metabolically Directed Functional Testing- This is a method of assessing several different mechanisms that control biochemical and physiological function. Acid-base balance, autonomic balance, anabolic-catabolic balance, electrolyte balance and blood sugar regulation can all be quantified through this method. Imbalances in any of the aforementioned control mechanisms can lead to a multitude of symptoms and long-term damage.
A Chinese Medicine evaluation based on characteristic signs in tongue diagnosis, pulses diagnosis, facial complexion, and body structure.
Functional testing can reveal imbalances in physiology, biochemistry, structure, energy and function. Once these imbalances are identified, a program to reverse them can be developed.
There is an ancient saying “an ounce of prevention is worth a pound of cure”. Utilizing functional testing methods can lead to true prevention of health problems.
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Written by: Roshan Dwivedi
As a video streaming platform owner, we are aware of the challenges and concerns you have with regards to your videos’ access, security and piracy. This is why Muvi takes utmost care in ensuring that technologically there are no gaps or leakages in our platform that will allow any unauthorized access to your videos. Muvi Studio boasts of top most security in both hardware and software including Firewalls, Encryption, DRM etc. to fend off pirates.
While speaking to all of you, we heard a common concern – how can we prevent screen capture software or recording off the screen using cameras?
Muvi today is happy to announce the launch of our Watermarking feature that tries to address this very problem. With watermarking enabled onto your accounts, whenever a video is played by your viewers, Muvi will discreetly display the users Id and IP address on the video player during video playback at random locations and random time intervals. This will be done in a non-intrusive manner, so that it doesn’t compromise the viewers video viewing experience.
With this feature, we take one step closer in making it difficult for someone to copy the videos illegally.
So go ahead and login to your account to enable Watermarking across your videos and let’s defeat video piracy together!
Not on Muvi yet? Click here to start your 14-days Free Trial and take our platform for a test drive.


Mo2 Properties Makes Your Life Easier, That’s Why!
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Using proprietary research, Expertise — an organization that helps people find the best local experts — selects the top service professionals in over 100 business categories in 1,000 geographical areas. Each business is assessed annually on the basis on reputation, credibility, experience, availability and professionalism.
In 2018, Expertise evaluated 703 property managers serving Chicago and picked the top 20. And guess what? Mo2 Properties made the cut! We were cited for our wide range of rental and construction management services, our knowledgeable and professional staff, and our responsiveness and flexibilities.


Dr Martin Walker
Martin is interested in the development and application of mathematical transmission and statistical models to: inform the design and implementation of interventions against tropical diseases; to assist with the design and optimisation of clinical trials of antiparasitic drugs, and to identify atypical antiparasitic drug responses potentially indicative of emerging drug resistance. Martin also has a number of methodological interests in statistical and mathematical aspects of infectious and non-infectious disease epidemiology.
Martin's current projects include:
Mathematical modelling of novel macrofilaricidal drugs for river blindness: from patients to populations? - Drugs for Neglected Diseases initiative - This project involves the development of clinical trial simulators and infection transmission models to optimise the design of antifilarial drug trials and to assess the potential epidemiological impact of new treatments as complementary intervention tools to accelerate progress towards the elimination of filarial infections.
Evaluating variation among anthelmintic drug responses to support the control and elimination of human helminthiases (QuoVadis) - World Health Organization/TDR - This project involves evaluating variation in individuals’ responses to the drugs distributed to millions of people around the world as part of the World Health Organization’s strategy of preventative chemotherapy to control and eliminate human helminthiases. This work will define expected levels of inter-person variation in drug responses for use as a reference to identify suspicious or suboptimal responses—potentially indicative of emerging drug resistance—in people exposed to multiple rounds of mass drug administration.
Modelling alternative treatment strategies for onchocerciasis: moxidectin for control and elimination - Medicines Development for Global Health - This projects involves projecting the potential epidemiological impact of using moxidectin—repurposed from veterinary to human medicine—to accelerate progress towards the elimination of onchocerciasis (river blindness) in Africa. The work will translate existing individual data from phase II and phase III clinical trials that show superiority of moxidectin over ivermectin—the current gold standard treatment for onchocerciasis—into population-level health benefits and revised timelines to elimination.


Saint Francis Solanus
Celebrated: on July 14.
The name in Old German means “free”.
Francis began his service in Spain, where he was also born. In 1589, he embarked as a missionary to South America to work with the indigenous people. He was accepted into the Franciscan convent in Lima. Over fifteen years of missionary work, following the example of the American apostles, he preached the gospel and baptized thousands of indigenous people. He healed the sick, advised leaders, and preached to the people, being considered a messenger of God by all. Later, Francis became the guardian of the Franciscan convent of the Queen of Angels in Lima, where he astonished everyone with miracles. He was given the name “the wonderworker of the New World.” Because of his virtue, he was admired throughout the Americas.
Patron of: Various places in South America have proclaimed him a special patron, following the example of Lima. He is also the patron saint of Argentina, Uruguay, Chile, Peru, Franciscan missions, and the missionary society.
Variations of the name: Francis, Fran, Frank, Frankie, Franny, Francy, Franciscus.


By Sierra Lauder, Director of Events and Downtown Development, Tillamook Area Chamber of Commerce
Happy New Year!! Things have been busy since the start of the 2018, with lots of progress on the bridge and the beginning of the development of the “Crosstown Connections” trail, along with curb, gutter, and sidewalk work. Demolition of the old bridge is underway this week, and the calendar is full of bridge work in the next couple of weeks as some big pours go in. If you’ve been to the Feed Store lately down on Front St., you’ve likely noticed the incredible progress at Sue H. Elmore Park, and maybe noted the new sidewalk and driveway from Front St. into Burden’s.
Along First near Pacific, the curbing in front of the Pioneer Museum is coming together nicely, and the intricate radial pattern that is designed for that space should be coming soon. On the Post Office side, the brick wall is being finished this week, and the next couple of weeks includes the electrical work, concrete and track for the new gate that will be installed into the rear parking area.
On Main, the heating oil tank that was discovered in front of Everything Pets has been addressed, and that space filled so progress on the remaining vaults and northern stretch of sidewalk can move forward. Access to Tangled Yarns will shift from the north (Second St. south along Main to the door) to the south (so you will approach from Third, passing Sunflower Flats, Annie’s Country Sportswear, and Everything Pets). Decisions about how to handle the more massive tank between Third and Fourth are still being made.
Meanwhile, excavation crews have plenty to do tackling the clearing and beginning of the trail making process for the new “Crosstown Connections” path. The photo above shows the design and path of the trail that will lead from the Hoquarton Slough all the way to Goodspeed Park. For those of you who might need more of an incentive to try that trail out, later this spring Werner Gourmet Meats will be opening their Deli and Tasting Room, where you can follow that trail from downtown all the way through Goodspeed Park and across Third St to the big flag and enjoy a pint of Werner Brewing Company beer and an amazing lunch. I’ll see you there.
Cheers to a fulfilling and rewarding 2018!


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over 25 years experience
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Newcastle Demolition is a family owned and operated demolition business. We have extensive experience in the performance of demolition works involving residential, commercial and government projects in the Newcastle, Lake Macquarie, Port Stephens Hunter Valley and Regional NSW areas.
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Dr. Paul Krebsbach, one of the nation’s leading researchers in tissue engineering and stem cell biology and a respected academic leader, has been appointed dean of the UCLA School of Dentistry.
Executive Vice Chancellor and Provost Scott Waugh announced today that Krebsbach will become the eighth dean of UCLA Dentistry, effective June 30. He will succeed Dr. No-Hee Park, who has served as dean since 1998 and is returning to teaching and research.
Krebsbach has been a member of the faculty at the University of Michigan since 1996. He is the Roy H. Roberts Professor of Dentistry and a professor of biomedical engineering, and he has served as chair of the department of biologic and materials sciences and division of prosthodontics since 2005. Prior to that, he was a senior staff fellow for three years at the National Institute of Dental and Craniofacial Research, one of the National Institutes of Health.
“Paul brings to UCLA a national reputation as an exceptional leader as well as a deep understanding of the unique mission of public research universities,” Waugh said. “I am confident that he will build upon the School of Dentistry’s tradition of excellence.”
The recipient of the International Association for Dental Research’s 2010 Distinguished Scientist Award for Basic Research in Biological Mineralization, Krebsbach is the author of more than 180 articles and chapters, and he holds two patents. His research focuses on the cell and molecular biology of mineralized tissues and self-renewal of adult and pluripotent stem cells. He has been the principal investigator of research funded by nearly $19.5 million in grants.
“I am thrilled to become part of the UCLA community of scholars,” Krebsbach said. “The School of Dentistry attracts the very best students and the faculty is exceptional. I’m looking forward to working together to take on the new challenges in dental education and to seizing new and exciting opportunities.”
For 10 years, Krebsbach served on the editorial boards of the International Journal of Oral and Maxillofacial Surgery and the Journal of Bone and Mineral Research. He currently is on the editorial boards of Bone Research, the Journal of Healthcare Leadership and the International Journal of Oral Science.
Krebsbach earned a bachelor’s degree in biology from the University of St. Thomas, a D.D.S. from the University of Minnesota, and a doctorate in biomedical sciences and certificate in periodontology from the University of Connecticut Health Center.
He is a fellow of the American Association for the Advancement of Science and the American Institute for Medical and Biological Engineering, and was awarded the William J. Gies Award by the International Association for Dental Research/American Association for Dental Research and an Independent Scientist Award by the NIH and NIDCR. Earlier this year, he completed a one-year term as president of the AADR, and he is a member of the American Dental Association, the American Society for Bone and Mineral Research and the IADR.


Welcome To ColfaxPolice.net!
We Protect & Serve Our Citizens
Colfax Police is a local law enforcement agency that serves the Colfax and surrounding communities. We are committed to providing exceptional service to our citizens, by enforcing the law and protecting life and property.
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"Serving with community pride"
To enforce the law using the principles of our mission statement in an on going effort to maintain a safe and secure environment for the citizens of the Village of Colfax.
ABOUT THE COLFAX POLICE DEPARTMENT
We've Been Protecting The Community Since 1892
The Village of Colfax was established in 1880, in Illinois.
The Colfax Police Department serves the citizens of Colfax with community pride.
Ritchie Cooper serves as Chief of Police and is aided by seven sworn officers.
Keeping our Schools Safe
The Village of Colfax Police Department provides police protection for the Ridgeview School District #19. It is our mission to keep Ridgeview safe for the students, faculty and families. If you have information that may help us achieve our goal please click here and you will be sent to our anonymous reporting. We need your information not your name. Let's keep Ridgeview Safe! GO MUSTANGS!
The Colfax Police Department will serve the citizenry utilizing a commitment to excellence and understanding. Officers are encouraged to find real solutions to real problems by listening and caring. The law will be enforced without bias or prejudice and our commitment to honesty and integrity will not be compromised.
Commitment to excellence - represents our commitment to the best training and equipment possible.
Understanding - represents a belief that the police department must represent the personality of the community and community leaders that it serves with appreciation for its concerns and tolerances.
Real solutions to real problems - represents problem solving policing, caring enough to get to know the people and identify the real problem so that real solutions can be developed. Quotas and production standards accomplish nothing.
WHO WE ARE
We Are Committed To Protecting & Serving The Community
The Police Department in Colfax, Illinois is committed to serving with community pride. The department's motto "Serving with community pride" shows how much they care about the people of Colfax and their safety.
News & Alerts
Halloween activities postponed until Saturday, 11/2/19! - Thursday, October 31, 2019
PUBLIC NOTICE - Monday, July 22, 2013
Dumping in Storm Drains Prohibited - Tuesday, July 3, 2012
Golf Carts and Recreational Off-highway Vehicles - Monday, November 21, 2011
Internet Crime Complaint Center - Wednesday, July 13, 2011
Warning: Phishing scam using local number on caller ID - Thursday, March 17, 2011
WARNING: PHISHING SCAM - Wednesday, June 16, 2010


Originally published: https://chrishedges.substack.com/p/the-chris-hedges-report-with-columbia
The Zionist movement from its inception has used deception, violence, ethnic cleansing and discrimination to solidify its apartheid state. The genocide in Gaza is another chapter in this 100-year war.
02 December 2023 | Chris Hedges Report
The conflict between the Palestinians and Israel, which has reached a terrifying crescendo with the savage obliteration of Gaza, is the outcome of a 100-year-old colonial occupation by Jewish Zionists in Israel backed by major imperial powers, starting with the British and a century later with the United States. This century-long assault by Israel has one objective – to force an indigenous people from their land. The historian Rashid Khalid breaks what he calls “the hundred years of war on Palestine” into six periods. The first is the British support for Jewish Zionists during the British occupation of Palestine from 1917 and 1939. The second declaration of war is the 1947-1948 Nakbeh, or catastrophe, that saw Zionist militias ethnically cleanse 750,000 Palestinians from historic Palestine and carry out a series of massacres. The third is 1967 war when Israel seized the West Bank, East Jerusalem and Gaza and expelled another 250,000 Palestinians. The fourth declaration of war on Palestine was Ariel Sharon’s invasion of Lebanon and the siege of Beirut, followed by the departure of Palestinian Liberation Organization (PLO) fighters to Tunisia and the 1982 massacre at the Sabra and Shatila refugee camps. The fourth war against the Palestinians began with the first intifada, or uprising in 1987, continued with the second intifada and is taking place with the Israeli brutal assault on Gaza. The backdrop to this century of war by Israel on the Palestinians is the failure by Arab leaders to offer meaningful support to the Palestinians, in fact these leaders often colluded with Israel to weaken the Palestinian resistance movement. Joining me in the studio to discuss Israel’s settler colonial project, how it is being played out in Gaza and its consequences, is Rashid Khalidi, the Edward Said Professor of Modern Arab Studies at Columbia University and the author of “The Hundred Years’ War on Palestine: A History of Settler Colonization and Resistance, 1917-2017.”


For the couple that loves to cook, enjoys intimate home gatherings and entertaining, our custom engraved rectangle cutting board is the gift of the season. Personalize this custom cutting board for a thoughtful and functional gift they'll love! It can also double as a cheese board for your best charcuterie presentation.
This custom engraved cutting board is designed and with a modern style and can be personalized with a last name + date. A must have holiday gift for the season!
To Order: Provide custom text in the provided text box. Custom text should follow the same format as what is shown. Extra text may result in additional fees. A digital proof will be sent via email to confirm the design is correct before we begin production.
// DETAILS //
Size: 14" x 10"
- * Color of cutting board and etching can vary from piece to piece. Some may be lighter and some darker. This is a natural condition of the bamboo.
- Sizing of custom text will vary depending on name length. Text will be scaled to a proportionate size for the cutting board.
- * Letters are computer generated using font styles that do not allow for manipulating how the letters appear.
All Happily Ever Etched products are designed & produced in-house.
By purchasing a custom item from Happily Ever Etched, you are agreeing to our Custom Order Terms and Shipping & Returns Policy.


Effective Flange Width of Steel Box Girder Bridge According to British Specifications and Japanese Specifications
- 10.2991/ifeesm-17.2018.247How to use a DOI?
- Steel box, Shear lag, Effective width
The British specifications and Japanese specifications are often referred to calculate effective flange width in order to analyze shear lag effect of steel box girder. However, there are some differences between the two specifications. According to the two specifications ,the effective widthes of a simple supported bridge, a continuous girder bridge with two spans and a continuous girder bridge with three spans are discussed. From the results, we can draw the conclusion that it is pessimistic and simple to calculate effective width of simple support beam according to Japanese specifications.The wide span ratio is the key factor for effective width of box girder bridge in British and Japanese specifications. It is more accurate to calculate the effective width of box girder bridge with British specifications.
- © 2018, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Huili Wang AU - Qi Wang AU - Sifeng Qin PY - 2018/02 DA - 2018/02 TI - Effective Flange Width of Steel Box Girder Bridge According to British Specifications and Japanese Specifications BT - Proceedings of the 2017 3rd International Forum on Energy, Environment Science and Materials (IFEESM 2017) PB - Atlantis Press SP - 1364 EP - 1368 SN - 2352-5401 UR - https://doi.org/10.2991/ifeesm-17.2018.247 DO - 10.2991/ifeesm-17.2018.247 ID - Wang2018/02 ER -


As one of the primary nutrition sources for humans, milk is a major agricultural product in many countries. Fat content is an important factor to evaluate milk quality, but current characterization techniques either involve complicated procedures or require expensive instrumentation.
Young-Tae Chang, National University of Singapore, and colleagues have identified a turn-on fluorescent sensor for rapid and sensitive milk fat measurements through a hyper throughput screening from 10,000 candidates. This BODIPY dye exhibits enhanced emission with increased fat content in milk samples, as a result of disassembly of aggregates that quench fluorescence.
The researchers have incorporated the sensing material into a fiber-optic-based detection system, enabling facile and convenient quantification of fat content in samples ranging from fresh milk to skim milk (0.1 to 4.2 % fat content). They believe this new system can significantly streamline existing milk quality control process.
- Milk Quality Control: Instant and Quantitative Milk Fat Determination with a BODIPY Sensor-based Fluorescence Detector,
Wang Xu, Jiaojiao Bai, Juanjuan Peng, Animesh Samanta, Divyanshu Arya, Young-Tae Chang,
Chem. Commun. 2014.


Our platform constructs two types of networks for users to investigate the lipid metabolism pathways and lipid-related gene enrichment.
The ‘Reactome Network’ contains the interaction of multiple lipids and genes and are summarized from the Reactome database,
which is a curated database encompassed pathways and reactions in human biology.
This function supports users to discover the metabolic networks between small molecules within Reactome Network topologies and their interactions with proteins.
We integrated the reactions in these pathways and explore the metabolic flow and regulatory proteins of the inputted lipids.
This information will be used to build an interactive network containing different nodes such as Biochemical Reaction, Small Molecule, Protein or Complex.
Lipid-related gene enrichment
By summarising the pathways from KEGG, Reactome, and GO databases, we present the functions networks of the user-defined lipid-related gene sets.
The mapped genes of the user-selected lipid class will be enriched and illustrated in the circular network diagram,
which allows users explore the significant functions and the relationship between lipid-related pathways and genes based on their lipid classes.


Ecole Normal Supérieur d’Enseignement Technologique ENSET-Skikda. Azzaba. Alger.
Université Mentouri Constantine faculté des sciences de l'ingénieur département de Génie mécanique.
The article deals with magnetic field of free convective flows in cavities similar to those used in artificial growth of single crystals from melts (horizontal Bridgman configurations) and having aspect ratios an equal to “4”. The combined effect of wall electrical conductivity and vertical direction of the magnetic field on the buoyancy induced flow of mercury was investigated numerically. The validation of the numerical method was achieved by comparison with both experimental and analytical data found in the literature. The plotted results for variation of velocity, temperature and Nusselt number in terms of the Hartmann number Ha and Rayleigh number “Ra” showed a considerable decrease in convection intensity as the magnetic field is increased, especially for values of “Gr” situated around 107. The calculations also showed that the vertically directed magnetic field (perpendicular to the x-z plane) is the most effective in controlling the flow and hence the speed of growth of the crystal. Also, wall electrical conductivity enhances damping by changing the distribution of the induced electric current to one which augments the magnitude of the Lorentz force.


Until now, there was no clear reason why sudden unexpected death in epilepsy (SUDEP) occurs. In a paper published today in the journal Brain, researchers have identified key aspects of fatal and non-fatal seizures.
SUDEP is unusual, occurring without warning in up to 12 per cent of people with epilepsy and up to 40 per cent of people with uncontrolled seizures, such as those not managed with medication or surgery (refractory epilepsy). SUDEP leaves no anatomical clues behind, making it difficult to understand how a seizure becomes life-threatening.
Building on CURE Epilepsy- and BC Epilepsy Society-funded research that Dr. Stuart Cain and Prof. Terrance Snutch began in 2014, the team has now identified regions of the brain that become inactive after seizures in mouse models. Depolarization of neurons is part of the process by which signals in the brain are normally transmitted between nerve cells. However, following seizures or traumatic brain injury, a severe and long lasting “spreading depolarization” occurs which instead silences activity as it moves through specific brain regions. This new research confirms that if spreading depolarization engages the brainstem, the result is fatal.
Seizures and migraine can engage similar processes in the brain, and so the team took a model with a genetic mutation found in humans causing chronic migraines and severe seizures, then monitored brain cell swelling that occurs simultaneously with spreading depolarization in real time via diffusion-weighted magnetic resonance imaging (MRI). What they found was that during fatal seizure events, depolarization spread to the brainstem, first arresting breathing; cardiac arrest followed, leading to death within a minute of the seizure. The brainstem plays an important role in regulating cardiovascular and respiratory function. In non-fatal seizures, depolarization did not spread to the brainstem.
“Spreading depolarization is the result of an intense excitement of the neurons, such as a seizure, followed by a long-lasting period of inactivity that travels outward to neighbouring neurons from the excitement point,” explains Dr. Cain. “It moves outward like a wave across the brain; the downstream silencing effect of the seizure depends on what region of the brain is affected by the wave.”
Dr. Cain and Prof. Snutch are hopeful that by identifying regions affected by cellular inactivity after seizure their team will be able to find a therapeutic target to prevent sudden death post-seizure. The next phase of this project aims to investigate potential drugs that may prevent the spread of depolarization into the brainstem. Dr. Cain is now involved in the next phase of drug development for neurological disorders at the Centre for Drug Research and Development (CDRD), where they are driving discoveries from the lab into new therapies in the clinic.
“At this stage we’re encouraged that our SUDEP model seems to be effective; these findings add to the fundamental understanding of the processes underlying SUDEP risk, and our model shows promise towards helping us identify predictive biomarkers in people with epilepsy at risk of SUDEP in the future,” says Dr. Cain.
- Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice (Brain, February 1, 2019)
- Commentary: Brainstem spreading depolarization: rapid descent into the shadow of SUDEP (Dr. Jeffrey Noebels, Brain. February 1, 2019)
- New funding to help find cause of sudden unexpected death in epilepsy


"Estate administration" refers to the procedure which must be followed when the estate of a person who has recently died is being distributed, either according to his or her wishes as laid out in a will, or the laws regulating the distribution of the assets of a person who dies without a will.
If the decedent (the person who died) left a will, the process of estate administration in Dyer Indiana will usually be carried out according to the instructions in the will.
Wills typically name an executor. The executor's role revolves around guaranteeing that the instructions in the will are implemented.
The person named as executor of an estate usually has some work ahead of them. To ensure that they actually follow through on their commitments, most people name as executor the person who will get the most money, or other benefit, if the will is given effect as written. Because an estate can't be distributed until the administration process is complete, the executor has an incentive to see it through.
What if The Will Does Not Name an Executor?
If a Dyer, Indiana will does not assign anyone to serve as executor, or there is no will, the court has to choose someone to fill that role.
This is most often the person who stands to gain the most from the will, or who would inherit the most under Indiana's intestacy laws. Intestacy is the system that every state has in order to deal with the property of people who die without a will. It usually distributes the property to the closest living relatives of the decedent, assuming they can be located.
If no executor is named in the will, anyone with a share in the will can apply to the court in Dyer, Indiana to be the executor of the estate, if they wish.
Whoever is assigned to serve as executor, it is their job to act as the representative of the estate. Among other jobs, they have to account for the decedent's debts and assets, and inform any beneficiaries who might be unaware of the situation.
Can a Dyer, Indiana Estate Administration Attorney Help?
If you are the executor of an estate, and don't know how to handle some of the legal and financial complexities that may arise, an experienced Dyer, Indiana lawyer can make this process a great deal easier.


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In conclusion, investing in real estate offers tremendous opportunities for wealth creation, and Stars & Stripe is an excellent partner to help you discover the best deals in the market. With their market research, diversification options, experienced team, and transparent communication, they provide a comprehensive platform for investors to achieve their financial goals.


If mom tips the weight scales, she may also tip her offspring, and subsequent generations, toward metabolic dysfunction. And mom’s influence may be conveyed through the maternal germline, which means that future generations could consume healthy diets and still be predisposed to obesity-related conditions such as type 2 diabetes and heart disease.
New research shows that a mother's obesity—and its associated metabolic problems—can be inherited through mitochondrial DNA (mtDNA) present in the unfertilized oocyte, or egg. This finding comes from a mouse study that was conducted at Washington University School of Medicine in St. Louis, where scientists fed female mice a high-fat, high-sugar diet from before conception until weaning and then followed the outcomes in the next three generations of offspring, all fed a control diet.
From 6 weeks prior to conception until weaning, the scientists fed mice a high-fat, high-sugar diet comprised of about 60% fat and 20% sugar. “This mimics more of the Western diet,” said Kelle H. Moley, M.D., the School of Medicine's James P. Crane Professor of Obstetrics and Gynecology. “Basically, it's like eating fast food every day.”
The results of a study led by Dr. Moley appeared June 16 in the journal Cell Reports, in an article entitled, “Maternal Metabolic Syndrome Programs Mitochondrial Dysfunction via Germline Changes across Three Generations.”
“We found that, despite consuming a normal diet, the first, second, and third generations of female offspring developed mitochondrial dysfunction and abnormal mitochondrial morphology in their skeletal muscle,” wrote the article’s authors. “Moreover, the mitochondrial dynamic proteins DRP-1 and OPA1 were misexpressed in the skeletal muscles of F1, F2, and F3 mice, suggesting an imbalance of fission and fusion. Mitochondrial abnormalities were also present in the germ cells of F1 and F2 females, suggesting that transmission of the mitochondrial phenotype occurred through the maternal germline.”
More research is needed to determine if a consistent diet low in fat and sugar, as well as regular exercise, may reverse genetic metabolic abnormalities.
“It's important to note that in humans, in which the diets of children closely mirror those of their parents, the effects of maternal metabolic syndrome may be greater than in our mouse model,” Dr. Moley noted. “In any case, eating nutritiously is critical.”
“Research, including this study, points to poor maternal nutrition and a predisposition to obesity,” Dr. Morely continued. “Our findings indicate that a mother's obesity can impair the health of later generations. This is particularly important because more than two-thirds of reproductive-age women in the United States are overweight or obese.”
In the current study, Dr. Morely and colleagues considered the possibility tha tearly-life exposure to maternal obesity affects the epigenome. There is already evidence that changes to the nuclear epigenome may promote metabolic disease in offspring. In addition, there could be changes to mtDNA. Such changes, which are inherited through the maternal germline, may provide a mechanism for transmission of metabolic dysfunction.
“Although we did not examine the epigenetic mechanisms leading to inheritance of abnormal mitochondrial phenotypes,” wrote the authors, “our data showing altered mitochondrial metabolism, morphology, and OPA1 expression in offspring germ cells suggest that both modification of nuclear-encoded mitochondrial genes and altered mtDNA play a role.”


Uriekste castle mound
Uriekste castle mound is located in Lizuma parish, in a remote, wooded area on the steep right bank of the Uriekste river, about 800 m NW of Lāčkaktu houses.
The castle mound is built on a half-kilometer-long, flat hill that stretches from southwest to northeast. Along the western and northern side of this hill, which is about 13 m high, flows along a meadow, huddled at the foot of the hill, the Uriekste River.
The slopes are naturally steep, without additional fortifications. In the direction of A the plateau becomes lower than ~ 1m, the river moves further to A, therefore the eastern slope of the castle mound is flatter and lower. The side of this castle mound is additionally fortified with a ditch, a fuzzy rampart up to 6 m wide, behind which there was again a ditch, which is now barely perceptible and is about 50 cm deep. Such a protection system encloses the rest of the plateau, because on the south side the slope is quite flat, but in the south the plateau of the castle mound is level with the rest of the plateau. The ditches and embankments on the south side are very blurred and drooping. In the west, the fortifications end on the steep bank of Uriekste.
The plateau of the castle mound is leveled, in some places small, sunken pits. The layer of culture is not found, gray sand is exposed under the moss. The whole castle mound and its surroundings are overgrown with spruce and pine trees, new Christmas trees are also starting to grow in the undergrowth, so the monument is quite difficult to see. No new damage.
People say that the castle once stood on the hill.
However, the low, wooded location and poor earthworks make this castle mound a war hideout.
The list of information source can be found here .


LONDON--(BUSINESS WIRE)--Growing digitization and significant technological advancements have propelled the innovation and growth of smart manufacturing. There are various crucial benefits to adopting smart manufacturing across industries and has become a necessary addition. However, efficiently adopting smart manufacturing, particularly through the COVID-19 pandemic, can be extremely challenging. How can companies successfully incorporate and reap the benefits of smart manufacturing? Infiniti’s custom market research solutions provide companies with crucial insights regarding market trends, market growth, and comprehensive data regarding smart manufacturing.
Request a free proposal to know how Infiniti’s data-driven market intelligence solutions are helping top manufacturers across the globe to strategically implement smart manufacturing technologies.
Technological advancements in the manufacturing industry have evolved substantially in recent years. Smart manufacturing is the most current, highly beneficial result of these advancements. Smart manufacturing can accurately predict requirements, identify errors, as well as make innovation and the manufacturing process more manageable. It is the process of combining and implementing various technologies and solutions into the traditional manufacturing process. The industrial internet of things (IIOT) plays a crucial role in successfully implementing these technologies and achieving business goals in the best possible way. Especially when the world is becoming predominantly digital, the manufacturing industry must be flexible and make this change. However, manufacturers need to leverage custom market research solutions and help their companies grow efficiently and strategically. In this article, Infiniti’s experts highlight the benefits of smart manufacturing and the benefits of custom market research for manufacturers.
“Currently, smart manufacturing is becoming the focus of manufacturing globally. It is the integration of the manufacturing industry and new-age information communication technology. As this change permeates the manufacture process in the form of smart factories and the adoption of industry 4.0, it is transforming traditional manufacturing for the better,” says a smart manufacturing expert at Infiniti Research.
Smart manufacturing is highly beneficial and crucial across industries and sectors currently. Infiniti’s custom market research experts highlighted the following significant benefits of smart manufacturing:
- Automated Data: Smart manufacturing provides managers with precise data and the ability to measure key performance indicators more efficiently
- Predictive Maintenance: Smart factory managers can predict and resolve maintenance issues better and faster
- Significant Cost Reductions: It increases forecast accuracy and reduces waste, helping reduce costs with proper demand management
- Enhanced Productivity: By providing seamless data on machine maintenance, potential bottlenecks, and other inefficiencies, it helps managers enhance productivity
Get in touch with an industry expert for more insights on implementing smart manufacturing technologies efficiently, and transforming your business.
About Infiniti Research
Established in 2003, Infiniti Research is a leading market intelligence company providing smart solutions to address your business challenges. Infiniti Research studies markets in more than 100 countries to help analyze competitive activity, see beyond market disruptions, and develop intelligent business strategies. To know more, visit: https://www.infinitiresearch.com/about-us


The commercial exploitation of the first wind farm in Russia with a capacity of 35 MW has been started. The wind park was built by Fortum (member of RAWI).
Work on the project was launched in December 2015, the company won an extraordinary tender for wind power, introducing the site in the Ulyanovsk region. In accordance with the terms of the tender, the capital costs for the construction of the wind farm to receive support were to be about 7 billion rubles. In the future, the selection of suppliers of wind turbines was chosen by the Chinese company DongFung, which supplied 14 wind turbines with a capacity of 2.5 MW each.
In February 2016, design work was started, and in May 2017 – construction work on the construction of a wind farm. In the design and construction of the wind farm took part mainly Russian companies, many of whom first participated in such a project.
Renewable energy sources have become the main business of the company in Russia To develop its wind energy business, the company jointly in the technological giant Rosnano created a fund for investments in wind energy. As a technological partner, Vestas (member of RAWI), a global company, has been selected, which localizes the production of its wind generators in Russia.
In accordance with the results of the competition in 2017, the joint venture Fortum and Rusnano – Fortum Energy LLC will build up to 2022 1000 MW of wind farms.


Information about Research:
The College of Science and Health Professions (COSHP) at King Saud bin Abdulaziz University for Health Sciences is home to three academic departments: the Basic Science Department, the English Language Department, and the Humanities Department. This diversity paves the way for a wide spectrum of research outcomes spanning various fields of study. Each department offers unique perspectives and approaches, fostering an active research environment within the college and opening doors for multidisciplinary projects.
Furthermore, the college actively promotes internal collaboration in research with King Abdullah International Medical Research Center (KAIMRC) and King Abdulaziz Medical City (KAMC). The college also supports external collaborations with organizations such as the King Abdulaziz City for Science and Technology (KACST) and the Ministry of Education.
In support of academic research and education studies, the college maintains a comprehensive database of student academic performance records. Researchers may access this invaluable resource once they secure approval from the Institutional Review Board (IRB) at KAIMRC. This database equips researchers with the essential data needed to conduct their education studies effectively.
COSHP is committed to fostering an environment that encourages collaboration and research, making resources accessible to further the pursuit of knowledge and excellence in basic science, humanities, English language, and educational research.
The college is actively promoting the research environment through
Establishing a dedicated research laboratory with the capacity to accommodate over 20 researchers, offering invaluable opportunities for faculty members to conduct their research. The current active research projects in the lab are centered around the fields of chemistry and stem cell research.
Employing highly qualified research assistants who play a pivotal role in supporting faculty members in their research endeavors. These assistants are involved in tasks such as data collection, experimental work, and data analysis.
Offering workshops such as "The Journey to Academic Promotion," designed to guide new faculty members through the research journey and provide resources and opportunities within the college and the university. These workshops also provide insights into research fundings and grant applications.
Providing an academic course, RESC 201 (Research Skills), aimed at introducing students to fundamental scientific research concepts under the guidance of faculty from the Basic Science Department. The course covers various research aspects, including different types of publications, research ethics (Institutional Review Board - IRB and plagiarism), essential research components (research questions/hypotheses, methodology, results, discussion/conclusions), and various referencing styles.
· Organizing a range of research activities, including
· Organizing Research Talk Series weekly.
·COSHP Poster Day.
·COSHP Research Annual Forum.
·Organizing Research Talk Series weekly.


What’s in a name?
Many people ask us about the meaning of our name, T’zikal. The short answer? It’s derived from the Mayan word meaning sanctified or blessed. It can also refer to something that is pure, cleansed or unburdened. This, in the deepest sense, reflects our approach to beauty, our reverence for nature and belief in the purity of true self care.
There are endless reasons to be drawn to Mayan culture. The Maya were a civilization who understood the power of simple, natural ingredients and honored the land that provided them. They were and are a people who cultivate interesting and effective beauty rituals that harness such ingredients, a people who value and ritualize healing, bathing and cleansing as key components of personal beauty. And we’re not the only ones fascinated and inspired by the Mayan approach to beauty – just look to the rising popularity of Mayan-inspired spa treatments.
Thus, in the initial exploration phase of the brand, we were led to an indigenous Mayan land and one of the most exquisite places on earth: the rainforests of Central America. Lush and pristine, brimming with natural riches – here is where we uncovered a legendary beauty secret and the heart of our collection: the ojon palm nut. With meticulous care, following time-honored traditions, we extracted its potent oil and harnessed its transforming powers. It naturally followed that we would choose a name from the culture that inspired and is the philosophical core of the brand.
We aspire to be the first Mayan prestige beauty brand. In that effort, we sought to further enhance the ingredients we’d discovered by engaging the most sophisticated European skincare labs, seeking to achieve a level of luxury that only modern science could provide. The result is a radically efficacious formula, one that, we believe, has earned the title of sanctified or, more aptly, T’zikal.
👉 Learn more about the brand and shop our collection.


OVER 50 YEARS OF EXPERIENCE
Crown Enterprises, LLC is a private, family-owned commercial real estate and development firm based out of Warren, Michigan. Our company has over five decades of experience in building out turnkey commercial real estate properties for large companies and enterprises across the United States and Canada. In addition to our turnkey commercial real estate development, we also operate as the landlord and manager of the properties we develop.
What separates Crown from the competition is our dual experience as not only commercial real estate managers and developers, but also business owners and landlords. We own all of the properties in our portfolio and our related companies operate within many of them. We know what it's like to be on the other side of the deal, which is why large brands put their full trust in Crown when it comes to even their most demanding projects.


Digital marketing has evolved into a cornerstone for businesses aiming to thrive in the online landscape. In this digital age, where consumer behaviors constantly shift, having robust digital marketing solutions is paramount for sustained success. Enter CognitoJS, a game-changing platform that redefines how businesses approach digital marketing.
In the vast realm of digital marketing, businesses are continually seeking innovative solutions to enhance their online presence and engage with their target audience effectively. CognitoJS emerges as a leading player in this space, offering a comprehensive suite of tools designed to streamline and elevate digital marketing strategies.
II. Importance of Digital Marketing
In a world where consumers are more connected than ever, the importance of digital marketing cannot be overstated. Statistics reveal a significant shift towards online interactions, making it imperative for businesses to invest in digital strategies for brand visibility and revenue growth.
III. CognitoJS: A Game-Changing Solution
CognitoJS stands out among digital marketing solutions, providing a unique set of features that empower businesses to navigate the complexities of the digital landscape with ease. From advanced analytics to personalized marketing campaigns, CognitoJS is a versatile tool for modern businesses.
IV. Target Audience and Customization
Understanding the target audience is crucial in digital marketing success. CognitoJS excels in this aspect, offering tools for precise audience segmentation and customization. Businesses can tailor their marketing efforts to resonate with their audience effectively.
V. User-Friendly Interface
One notable feature of CognitoJS is its user-friendly interface. In an industry often plagued by complexity, CognitoJS simplifies the user experience, making it accessible even for those without extensive technical expertise.
VI. Analytics and Insights
Data-driven decision-making is at the core of successful digital marketing campaigns. CognitoJS provides robust analytics and insights, allowing businesses to glean valuable information and optimize their strategies for maximum impact.
VII. Integrations with Other Tools
CognitoJS understands the importance of a cohesive marketing stack. The platform seamlessly integrates with other tools, ensuring a smooth workflow and enhancing the overall efficiency of a company’s marketing efforts.
VIII. Case Studies and Success Stories
Real-world examples speak volumes. CognitoJS has a track record of contributing to the success of businesses across various industries. Case studies and success stories highlight the tangible benefits, from increased ROI to substantial brand growth.
IX. Future Trends in Digital Marketing
As digital marketing continues to evolve, businesses need solutions that can adapt to emerging trends. CognitoJS remains at the forefront, consistently updating its features to align with the future of digital marketing.
X. Pricing Plans and Affordability
Affordability is a key consideration for businesses of all sizes. CognitoJS offers transparent pricing plans, ensuring that businesses, whether startups or enterprises, can access powerful digital marketing tools without breaking the bank.


Helicity Space, an in-space nuclear fusion propulsion startup, nabbed a $5M seed round to begin developing its novel engine.
The funding will allow the Pasadena, CA-based company to advance R&D of its recent breakthrough discovery of extremely stable plasma jets used for fusion reaction. Investors include Airbus Ventures, TRE Advisors, Voyager Space Holdings, E2MC Space, Urania Ventures, and Gaingels.
Fusion 101: Nuclear fusion (the opposite reaction to the more common fission) is the process that powers the sun. However, harnessing the energy source on Earth—let alone in space—has proven difficult, with only one net energy fusion reaction ever achieved.
Mini-sun engines: If and when it can be mastered, fusion could offer a near-inexhaustible energy source, potentially revolutionizing space propulsion by allowing spacecraft to travel farther, faster.
“In the space sector, fusion propulsion has been the holy grail since the 60s,” Helicity cofounder Stephane Lintner told Payload. “Fusion is the only reaction that gets you a level of energy that allows you to break away from the limits that we have right now with chemical.”
- Conventional chemical propulsion generates very high power but expends fuel quickly.
- Electric propulsion is fuel-efficient but is limited by power and thrust.
Mars, Jupiter, interstellar: The company says that when its Helicity Drive engines are operational (at least 10+ years out), it could propel a spacecraft to Mars in two months, Jupiter in one year, and interstellar space in just ten years. For comparison, it took NASA’s Perseverance rover about seven months to reach the Red Planet.
The company and its investors are well aware of the magnitude of the work ahead. Helicity will have to master the fusion reaction before it can look ahead to developing operational engines. The company’s product roadmap:
- 2026: Demo its plasma jets reconnecting—before fusion net gain.
- 2032: Test flight with fusion augmenting solar electric propulsion.
- 2040s: Self-sustaining engines.
Geek out: Helicity’s fusion engines will employ a pulsed magneto-inertial confinement technique. How it works:
- Multiple plasma jets are shot along a track in the engine.
- The jets merge and compress, reaching fusion conditions at 100M degrees Fahrenheit.
- The fusion reaction fuses deuterium (hydrogen) atoms, resulting in energy for direct thrust.


A study printed within the 2010 publication of the Australian Dental Journal says about 16% of adults around australia have a very high dental fear. Such dental anxiety might not appear just like a serious problem, yet it will have major implications on the healthiness of many Australians.
If somebody is scared of going to the dental professional, he/she’d finish up getting poorer dental health in addition to going to the dental professional less regularly. Fundamental essentials sort of people that simply do not show up for his or her scheduled appointments using the dental professional or perhaps cancel such appointments.
Why People Fear Dentists
Individuals who fear dentists have different causes of their fear. In a few instances, adults have painful recollections, etched inside their minds, of bad encounters they experienced when going to the dental professional throughout their childhood years. Indeed, children could be deeply impacted by painful encounters as a result of united nations-empathic dentists, that will keep on into the adult years.
In some cases, many people might have the mistaken thought that dental care would hurt. Fortunately, dental professionals are more and more conscious of their patients’ fear. Dentists are adopting effective, patient-friendly ways of provide stress-free and mild dental hygiene to any or all patients.
Through a number of methods, dental professionals can effectively identify and counter dental anxiety in patients.
Need For Dental professional Visits
A realization of the significance of regular dental check-up may help you overcome your fear. Being able to access services is instrumental in making certain good dental health. Indeed, the Ada recommends that adults must have a verbal visit at least one time inside a 6-month period.
You need to understand that dentists don’t merely treat dental health problems. Additionally they serve the vital role of assisting you maintain healthy teeth and gums. Which means that regular dental visits could make you less vulnerable to poor dental health.
Some Other Reasons For Staying away from Dentists
Fear is not the only real reason people avoid dentists. A number of other reasons exist, including cost constraints. A 2011 report printed within the Australian Institute of Health insurance and Welfare reveals which more than one-third of Australian dentate adults either delayed or completely prevented going to the dental professional due to cost issues.
Not getting dental insurance plans is yet another component that plays a role in avoidance of dental visits. A 2011 study through the Australian Institute of Health insurance and Welfare reveals that double the amount number of uninsured adults (45%) prevented going to the dental professional, when compared with insured adults (22.9%). This highlights the critical role that insurance plays in dental health. Upfront barriers, particularly, really are a potential barrier that insurance will help overcome.
Patient indifference is yet another aspect that includes to avoidance of dental visits. This kind of indifference towards dentistry can adversely affect dental health.
There also exist instances by which people only go to the dental professional like a last measure. Instead of opting for regular dental check-ups, they merely go to the dental professional when impacted by particular dental issues. This is not advisable since protection against dental issues (permitted through regular dental visits) is a far greater dental health plan when compared with management of dental issues.


At CES 2013, Asus has shown off an All-In-One PC that runs Windows 8 when it is docked and can run Android 4.1 Jelly Bean when it is tablet mode. The device boasts of a giant 18.4-inch IPS Full HD display.
Asus has added yet another device to its Transformer line up. This time it’s an AIO (All-in-One) desktop that can transform into a tablet. The beauty of this device is that it will give users the best of both worlds – Windows and Android. Yes, the device runs Windows 8 as well as Android 4.1 Jelly Bean.
When docked in, the device is powered by a third-gen Intel processors and Nvidia discrete graphics. When removed from the dock, the tablet is powered by an Nvidia Tegra 3 processor for running Android. Switching between the Oses is as simple as pushing a button.
The Asus Transformer AiO has an 18.4-inch Full HD 1920×1080 pixel IPS display and users can still access the Windows 8 desktop via a wireless connection if they wish. In its press release Asus has said, “makes it easy to carry the tablet from room to room and a built-in stand keeps the display at the perfect angle for tabletop use.”
The Transformer AiO adds support to an integral handle that makes it easy to carry the device while on the go. How this translates in the practical world still remains to be seen, as carrying an 18.4-inch device doesn’t sound extremely convenient. Asus has 16GB of storage on the Android side for the tablets use, and 1TB storage for Windows 8.
The device is expected to hit store shelves in Q1 2013 and can have a starting price of $1,299.


For a retailer for professional mobile phone units, I'm typically requested what requirements needs to be viewed as when revamping or changing a company mobile phone technique. When there are various personal things to consider which are precise to every situation, The majority of these tumble under the umbrella of realizing what you may have and what you will need, and finding the best cost.
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Future, you should discover the functions you will need at the lowest selling price. In truth, it’s as simple as it Appears. Should you be increasing, you may simply increase a lot more lines and handsets at the side of your recent setup, so capabilities genuinely don’t implement Except that you are upgrading handsets. In case you are only growing the same set up, you will be roughly relegated to adding additional of what you already have. In case you are changing a cellular phone process, even so, features and rate are your main consideration.
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Scripture Read: Genesis 29 - 30:24
Title: The Deceiver is Deceived and God is Still in Control
(H) Highlight verse:: "So Jacob served seven years for Rachel, and they seemed to him but a few days because of the love he had for her" Genesis 29:20
(E) Explain: The plot thickens. The deceptions run deeper. Jealousy and envy abound. I continually say that this family account could easily be a soap opera and daily, we see why. However, in all of this deception (Laban tricks Jacob into 14 years of service for two daughters in marriage, when he only had eyes for one), jealousy (Jacob loved Rachel more than Lean, but Leah gave him children), human intervention (To "get back" at her sister Rachel gave Jacob her servant Bilhah to him father children with her and Leah gave her servant Zilpah to have children with him), God was still at work. In this hot mess of a family where bitterness and jealousy were rampant, God was able to make something good come from it. God took four mothers and one father to establish or bring about the 12 patriarchs of Israel Yes, God worked wonders out this chaos.
(A) Application: Humans make messes. We/I do stupid things on a daily basis. I like to "help" God in running my life. The problem is, I allow sins to be present in my life and ultimately these sins affect my life and my relationships. I do a fantastic job of tearing apart something that God has created. I am like a child, sometimes, who likes to disassemble things, just to see how they work and my disassembling often ends up pretty bad. Fortunately, God is patient with me and puts back together that which I tore apart. God is in control and He knows what He is doing. I love that God can take a disassembled mess and make a beautiful thing out of it.
(R) Respond: Thank you for being patient with me God. I love that you remain faithful even when i am not. May I live this day in a way that gives you full control of my life. May I not meddle with what you are doing, but also may I not sit back apathetically and do nothing. I want to be in tune with you, so I may do what you have planned for me this day.
Jeff has been in full-time ministry for thirty years. He currently serves as Executive Director at Anchor House Ministry at SeaPort Manatee in Palmetto, FL and he is a part-time Campus Pastor at West Bradenton Southside in Bradenton, Florida.
Jeff Has authored A Lent Devotional (A Spiritual Journey to Lent) an Advent Devotional (The Advent of Jesus) and a devotional on the book of James (James: Where Faith and Life Meet). All three are available on Amazon.
He is married to Carrie and they have four children, Micaiah, Gabe, Simon, and Berea.
Preview or purchase Jeff's Books


Knot theory is a branch of topology that deals with mathematical knots and links. A knot is an embedding of a circle into the 3-dimensional space. A union of knots is called a link or a catenane. As the chromosome of E. coli is closed circular, the core axis of its double stranded DNA can be considered as a knot. A site-specific recombination of DNA can be modeled mathematically by using a band surgery, a local move on a knot or a link as in the figure below. In biological experiments it is observed that some site-specific recombination reactions change the topology of DNA. Using this topological information, we can characterize the mechanisms of the site-specific recombination reactions as applications of results on band surgeries.
In our recent study, applying new mathematical results we characterized unlinking of replicated chromosome of E. coli by the FtsK-dependent XerC/XerD-dif recombination. There we determined the number of recombination steps needed to unlink replication catenanes. We showed that the stepwise unlinking as in the figure is the only possible pathway if we assume that the crossing number of DNA knot or link is reduced at each recombination. We also characterized the topological mechanism for these unlinking reactions.
Reference: “FtsK-dependent XerCD-dif recombination unlinks replication catenanes in a stepwise manner”, Koya Shimokawa, Kai Ishihara, Ian Grainge, David J. Sherratt, and Mariel Vazquez, Proc. Natl. Acad. Sci. U S A (in press).


Long before the Metro began transporting passengers between Newcastle and the suburbs, the so-called ‘Tyneside electrics’ ran the lines.
The move to suburban electric trains in the early 20th century came as a result of North Eastern Railways losing nearly four million passengers to the expanding tram system in the two years between 1901 and 1903.
The electrics ran successfully until the 1960s when falling passenger numbers and outdated rolling stock and infrastructure led to their withdrawal and replacement by diesel trains.
The last electric train ran south of the river in 1963, and north of the river four years later.
When Metro began operating in 1980, it incorporated much of the former electric network.
These largely unseen pictures recall the long-gone ‘electric multiple units’ - trains - and some of the stations on both sides of the Tyne in the 1950s and 1960s.
They are published courtesy of the Armstrong Railway Photographic Trust. The trust was formed after the death in 1987 of lifelong railway enthusiast Jack Armstrong from Northallerton.
During his long life, Jack had taken a comprehensive and significantly historic collection of photographs mainly in the North East. He recorded not only trains but stations, signal boxes and virtually every area of railway infrastructure.
A group of North East-based railway enthusiasts raised sufficient funds to purchase the whole collection. Thousands of images have now been digitised.
Trustee David Dunn said: “Armstrong Railway Photographic Trust has over 330,000 images mainly on railway subjects, but also ships on the Tyne, buses, collieries, and more.”
If you have any old North East transport images you’d like to add to the Armstrong Trust collection, email David at firstname.lastname@example.org


Trend-setting 5-axis technology to facilitate economical machining of complex geometries.
The measure of all (milling) things.
The trendsetting 5 axis technology in hyperMILL can typically yield time savings of more than 25 per cent while lowering tool wear and increasing contour accuracy for more cost-efficient production thanks to continuous machining. Challenging geometries such as high and steep walls require many different tool inclinations in precisely delineated milling areas.
5 axis simultaneous machining with hyperMILL 5AXIS is based on what users are already familiar with: milling with a tilted tool. Yet the machining process is now quicker, the surface results are better and programming is much less complicated. Thanks to easy programming with automatic collision checking and avoidance, this technology can also be used as a solution for many standard milling jobs.
- Easy programming for milling applications with indexed orientation.
- Process reliability due to proven fully automated collision checking and avoidance.
- Multiple tilt strategies are available: 3+2, automatic indexing and 5 axis simultaneous machining.
- Familiar 3D strategies, such as Z-level machining or rest machining have been expanded to include 5 axis processing.
- A broad spectrum of machining strategies for surfaces, cavities and special machining tasks.
- All 5 axis strategies are available in the hyperMILL® interface.
- 5 axis shape offset roughing and finishing for simple and time-saving programming of shaped and wrapped surfaces.


This time of year has always held a particular place in my heart, mostly because it's right around my birthday. And this birthday year is particularly special because it happens to be my 40th on this planet. As I retrospect on my existence, I must say that I'm content with my place in this world, and I wish the same for you.
I also love this time because we have begun laying the groundwork for our garden. Though it may look barren, there is potential for future growth. The trees are just blossoming with fragrant white plum flowers and delicate pink peach flowers. Though the threat of deer attacks is omnipresent, I'm feeling especially optimistic this year.
GAIA REBORN BOOK LAUNCH
The big news I have to share is the official launch of GAIA REBORN! The second book in the Ascended series, GAIA REBORN takes place two years after the events of GAIA HUNTED. The novel is available for sale at your favorite retailer. Below is the blurb of the novel and a link to the first chapter.
Of course Mattie Fisher runs away. Her power to remember past lives is threatening her stability. Every dream pushes her deeper into the abyss as the voices from the past crowd her very sense of self.
Hawaii seems like the perfect place to hide for the rest of her life—until she’s discovered by the gods of war, who want her dead, and Jared Stone, the man she loves but swore she’d never see again. They drag Mattie back into the world of the Ascended.
To survive, Mattie must harness her powers at the Lyceum, a school deep in the desert. She assumes the gods there are allies but soon learns that they’re as dangerous as any enemy she’s ever faced.
The only way Mattie will live is if she conquers her fears and fully embraces a destiny that could destroy the very people she wants to protect.
READ the first chapter
ORDER GAIA REBORN
Thank you for all your support and I hope you enjoy GAIA REBORN.
Be well and happy reading!
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Italian Referendum: Gold Confounds—Again
Recent events (the Austrian vote, the Italian referendum) that could have boosted the gold price have had the opposite effect. As with the Brexit and Trump’s election, gold spiked up but came down sharply, giving fuel to the conspiracy theorists’ claims that the financial and governmental elite is working in suppress the global gold price.
Strength in gold is seen as recognition that the global economy is in a dangerous state, and neither the big money nor the politicians want to see this interpretation gain credence. For the former it would mean a market collapse, destroying wealth, and for the latter it would damage the perception that all is well with the global economy, despite indicators that this is not the case.
Modern day politics is about perception. If people believe that all is well they will spend at levels that will help the economy. In the US there is plenty of evidence that the average person is worse off than they were a few years ago. Yet there was a consumer spending splurge on Cyber Monday that broke all records. This is unsustainable, but when will the myth that all is well with the world be understood by public?
A comfortable existence may be on the way out. There are votes against the establishment, but in no case has the majority been large enough to carry much more than 50% of the vote, so there are still a substantial number of people who are happy with the status quo. The protest vote will have to grow if there is to be any serious perception change.
Part of the underperformance of gold after the Italian result has been put down to dollar strength, given a sharp fall in the euro, as the result is seen as having the potential to upset the euro and precipitate an Italian banking system meltdown, with an adverse effect on the whole European banking sector, to which the Italian banks are severely in debt. But the resultant dollar strength has been short lived, while gold has remained around $12 down on its Friday close.


The History of Shenandoah Medical Center
For nearly 100 years, Shenandoah Medical Center has provided exceptional healthcare to the residents of Shenandoah and the surrounding communities. It began in 1911 with a donation of $25,000 by Catherine and Henry Hand for the erection of a hospital building. In 1918 the construction of Hand Hospital was complete.
This early facility had very simple equipment, with no laboratory or x-ray capabilities, and only a skylight for illumination in the operating room. By 1920, thirteen doctors served at the hospital. Many miracles were performed and lives were saved, despite treacherous mud roads leading to the hospital, no antibiotics, and limited resources.
In 1976, changes in medical care and advances in technology moved the hospital to consider extensive updates. A fundraising drive resulted in a gift of 10 acres from Jack Foster, an adjoining 1.2 acre gift by Edward May, and $3.5 million from donations and bond sales. A new, 44-bed hospital with improved facilities was constructed and opened in 1979. The new building was renamed Shenandoah Memorial Hospital.
Throughout the years following, renovations and improvements continued. In 1993, the hospital announced plans for an expansion to provide state-of-the-art treatment of cancer and kidney dysfunction, launching the Clarkson Cancer Institute and Kidney Dialysis Center the following year. In 1998, the Shenandoah Outpatient Clinic facility was opened. In 2004, a new Disease Prevention & Wellness Center was completed, and in 2006, a new women’s health clinic was launched. The hospital was renamed Shenandoah Medical Center.
While facilities and technologies have changed over the years, our dedication to the Shenandoah area has remained consistent and unwavering. We proudly stand in a rich history of enhancing the health and lives of the people of our community.


The message reads, in part:
“I would like to congratulate you on the 10th anniversary of the Russian Historical Society’s reconstitution. Relying on many traditions created by Society members in 1866, the reconstituted RHS has pooled the efforts of the state, society and professional historians to create a national historical culture, preserve national history and foster objective historical knowledge at the nationwide level and in individual regions of Russia.
An active and creative stand of RHS members, including the leading research institutions, universities, museums, archives, libraries and individual historians, is helping enhance the standards of historical education, increase the accessibility of archival heritage and strengthen the positions of the national historical science. Of great importance today are the RHS education projects, which are designed for a broad range of young people interested in history.
The Russian Historical Society has always been noted for professionalism, commitment to the historical truth and respect for all periods in our past. During the ongoing special military operation in Ukraine, the RHS has reaffirmed its solid patriotic stand through deeds and is doing an important and much-needed job.”


Consistency is not necessary: One positive study is not counterbalanced by a negative one. It can be easier to fail to find an effect than it is to prove an effect exists. The Seletun Scientific Panel notes that complete “consistency” of study findings is not to be expected, and it should not be interpreted as a necessary pre-condition for a consensus linking EMF exposure to health impacts. “Consistency in nature does not require that all or even a majority of studies find the same effect.” 8 This sensible sentiment is corroborated by the WHO, “A demand for scientific proof is always a formula for inaction and delay and usually the first reaction of the guilty … in fact scientific proof has never been, is not and should not be the basis for political and legal action.” 9
Author of page Dr. Erica Mallery-Blythe, see credits for graphics owners. If you wish to use or discuss any content from this site, please contact the relevant author / owner either directly or via ‘contact’ above. A link to the references for each section will also be coming soon.


Defeating The Threat
Allen-Vanguard is a leader in providing customized solutions for defeating Radio Frequency (RF) based terrorist and extremist threats; these include the continued global threat posed by Radio Controlled IEDs (RCIEDs) and the increasing prevalence of Drones (Unmanned Aerial Systems (UAS)) used for both nuisance and more lethal means. Defense Forces, Public Safety & Security agencies around the world trust our capability solutions to provide integrated capabilities to help save lives every day.
All of Allen-Vanguard’s capabilities are developed and delivered in conjunction with domain knowledge experts and intimate support is provided by our Field Service Representatives, who are subject matter experts in the field of RF protection systems. Their front-line experience in combat theatres, law enforcement and intelligence ensures that customers receive the analysis, advice, training and support necessary to foresee and prevent current and emerging threats.
Users worldwide trust Allen-Vanguard capabilities for protection of personnel and facilities to ensure safe and secure freedom of movement as they complete their dangerous missions. Our operationally proven systems are developed in close collaboration with end users, tested to provide the highest levels of assurance and supported worldwide to ensure maximum operational availability.
To learn more about how Allen-Vanguard can provide your organization with a customized and integrated solution, please contact your authorized Allen-Vanguard representative today.
Mike joined Allen-Vanguard as our Electronic Warfare Director in November 2004 after having served over 28 years in the Canadian Army.
President/General Manager Electronic Systems
Mike spent the majority of his career in the fields of Signals Intelligence (SIGINT) and Electronic Warfare (EW). Career highlights include Officer Commanding the Canadian Detachment at the National Security Agency at Ft George G. Meade in Maryland where he was employed in the Operations Directorate. He also served at the Medina Regional Security Operations Center (MRSOC), San Antonio, Texas. In addition to his operational duties, he was a member of the Board of Directors of this 1800 plus organization that was responsible for strategic direction and planning for a multi-service organization that included Army, Marines, Airforce, Navy and civilian personnel. In 2002 Mike was selected for a tour in Afghanistan as the Officer-in-Charge of the multi-national Signals Intelligence Electronic Warfare Operations Center (SEWOC) and ECM/EW advisor to the Kabul Multi-National Brigade Commander and also served as the Senior Signals Intelligence officer for Canada.
Mike has served in a variety of positions at Allen Vanguard, including engineering team lead for the UK, ECM program director, ES Business Develop Lead, as well as his current role of President and General Manager.
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Dying without a will can have a devastating impact on a family. Without a will, property is divided according to state law, without regard to your wishes or expectations. Beloved family members and friends who do not fall under the intestate succession laws could be left with nothing while distant, unknown or estranged family members may inherit your property. A simple will can help avoid dying intestate and keep your family together after your death.
The loss of a friend or family member can be a tragic time. However, fighting over their money and property can bring out the worst in people. When an individual prepares a clear estate plan to distribute their property, everyone involved understands that the property was distributed according to the decedent's wishes. Without an estate plan, battles over property distribution can tear a family apart.
An individual who dies without a will is considered to have died “intestate”. Without an estate plan in place to transfer property, the courts will step in to distribute the decedent's property through a process known as probate. This can be an expensive and drawn-out process that leaves grieving friends and family in limbo for months or years.
During probate, the court will identify and inventory property, appraise the value of property, pay out any debts and taxes, deduct court, legal and probate fees, and distribute any property left over according to state intestacy laws.
Under California intestate succession laws, a surviving spouse generally receives the decedent's share of community property. If there are no surviving children, parents, siblings or children of siblings, the surviving spouse receives the decedent's separate property. If the decedent left at least one parent, child, sibling or child(ren) of a sibling, the surviving spouse gets either (a) half of the separate property; or (b) one-third, if the decedent left more than one such issue.
Without a surviving spouse, the distribution of property can be more complicated, depending on the number of descendants, children, grandchildren, parents, siblings, grandparents or nieces and nephews. If there are no surviving heirs, the decedent's property is usually distributed to the State of California.
California's intestacy laws can be confusing, especially given the makeup of modern families. A couple separated for years may still be considered married under the law, while a long-term partner may have no legal claim for property of the estate. If the individual or couple moved between states over the years, their property accumulated over that time may be partially considered individual property or common property. This can lead to unintended and unequal distribution of their property after death and cause fighting between family members.
There are separate considerations regarding half blood relatives, adopted children and individuals who do not survive very long after the decedent passes away. Individuals involved in killing the decedent, or abusing an elderly decedent may be prevented from benefiting from their actions. Talk to your attorney with any questions about intestate succession or property transfers after death.
If you have any questions about estate planning, making a will or preparing a trust, contact Butterfield Schechter LLP. We will advise you on your estate planning options, help you protect your family, and avoid conflicts that can later tear families apart. Contact our office today with any questions on how we can help you and your family succeed.


A conference in the metaverse? An idea of a faraway future? No – actual reality in the here and now – as being part of Immersive X, a conference set in the Metaverse.
DEXLab's founders, Roberta Di Palma and Jonas Heller, presented a novel perspective on personal branding in the virtual space. Their session revealed into the transformative potential of Virtual Reality (VR) in enhancing personal presentation skills, a crucial aspect of professional development and personal branding.
Their presentation, "Excel in Personal Branding: Exploring VR’s Potential to Improve Personal Presentation Skills", highlighted the importance of crafting a unique professional identity in today's competitive market. They emphasized how enhanced presentation skills, one of many crucial soft skills of the 21st century, can significantly influence career opportunities, trust-building in professional relationships, and visibility across digital platforms.
The duo stressed the role of VR in training and upskilling, especially in university settings where the foundation for critical thinking, collaboration, creativity, and communication skills - the 4Cs - are laid. They presented compelling research indicating the effectiveness of VR in reducing public speaking anxiety, thereby bolstering presentation skills - a requirement in 40% of job descriptions across various fields.
A key focus of their talk was the integration of Constructivist and Situated Learning Theories in VR training. This approach enhances learners' experience by situating them in realistic and social contexts, thus improving motivation and learning outcomes. Their research underscores the role of feedback mechanisms and presence factors in VR and their impact on motivation, learning, and skills transferability.
The presentation concluded with practical implications for VR training design, emphasizing the importance of balanced social and spatial presence in VR environments to foster effective personal branding. This balance, they argued, is crucial in avoiding overwhelming scenarios while maintaining focus on brand goals.
Their talk at Immersive X not only illuminated the path for personal branding in the VR world but also set the stage for future innovations in VR-based learning and development. As pioneers in this field, Di Palma and Heller's insights have the potential to revolutionize how professionals present and brand themselves in the ever-evolving digital age.


The Essentials of – 101
Families at times face challenges in determination of parenthood among some of their siblings. In such an instance, it means there is need to seek for testing solutions that help determine the dna connection of the siblings through use of the prevalent need. Of importance when sourcing for the kits is to ensure that the it comes with ease of usage as well as the accessibility factors. They come in handy to help avoid the high cost of laboratory home testing while removing any doubts that may be prevalent within the family.
There is need for an easy process when sourcing for the kits to be used for dna testing. Identification of a reliable dealer therefore comes in handy and this serves to ensure the kit comes in the right packaging. The dealer selected therefore needs to have a platform created through which the buyers easily get the opportunity to source for the products. Researching and consulting with industry players in this respect comes in handy to ensure that the buyer makes informed choices.
Among the things of importance in dna testing is to ensure that the user gets accurate results. The results sought in the process entails having the right parental connection between certain siblings. This also has an impact on the siblings to undergo the test. Kits sought to serve the prevalent needs therefore needs to among other things have the right quality and an assurance on performance. Authentication and certification of the kit comes in as important factors to be considered in the process.
At home dna test kits come in different format. Both personal and legal results are generated using different models. The personal kits in this respect produces results that can only be used within the family level. While seeking for results to use on legal matters, there is need as well to seek for the recommend kits to the purpose. For this reason, there is need to ensure that the sourcing process clearly indicates the intended usage of the results. Provision of the information therefore serves o guide the dealer in selection of the kits to provide.
Every community comprise of a certain range of families. The parents and siblings however need to know their right and correct parentage. It is for this reason that dna test kits comes in handy. With the need to have accurate the right results, the buyer must undertake due consideration of the available choices and ensure they pick only kits that are genuine and with capacity to deliver. This entails among other things seeking for a genuine dealer who provides with the right and accurate kits to serve the prevalent needs.


Job Opening | Editor 'Index Buddhicus'
Brill Academic Publishers is looking for two to four indexers for its new bibliography for Buddhist Studies -edited in close collaboration with the Käte Hamburger Kolleg 'Dynamics in the History of Religion' at Ruhr University's Center for Religious Studies. The workspace is situated at Ruhr University Bochum, Germany.
The Index Buddhicus will be the academic bibliographical reference in the field of Buddhist studies. It will consist of bibliographical records for monographs, reviews, chapters in edited volumes, journal articles, reference works, electronic resources, and whatever is deemed relevant. The Index Buddhicus will cover Western language secondary literature.
Indexing will be done online on the basis of detailed instructions and guidelines. In their daily work the indexer(s) will report directly to their supervisor the managing editor, Mr. Richard Mahoney.
- the identification of (sources of) relevant secondary literature
- editing and feeding the resulting bibliographical records into the Index Buddhicus database
- linking each record to a carefully designed classification and keyword list
- advising the managing editor on further optimisation of the classification and keyword list
- supervising the work of external bibliographical correspondents
- advising the managing editor and publisher on issues such as representation at conferences, marketing opportunities, improvement of the user interface, etc.
- preparing any spin-offs from the Index Buddhicus database
- min. MA level knowledge in the field of Buddhist Studies
- preferably experience in bibliographical work
- be meticulous and efficient while at the same time
- be well-versed in working with databases and aware of developments in electronic publishing and usage.
- be able to work within deadlines
The editors will be appointed on a project basis, but in the longer run a fixed position within the framework of the project belongs to the possibilities. The position is on the basis of a 50% to 75% full-time equivalent. Initial duration is for the period of twelve months. Salary is an hourly basis ranging from € 15 - € 18. Indexing a sample of articles will be part of the selection procedure. The project will officially start in December 2013 or January 2014.
In case you are interested, please contact Prof. Sven Bretfeld, Ruhr University Bochum, Universitaetsstr. 150, FNO 01/176, 44780 Bochum. Applications should be send in digital form (pdf) to sven.bretfeld[at]rub.de before 22 October.