Public procurement notice: Voluntary Ex Ante Transparency Notice
Published: 2021-04-16
Buyer: Oslo Universitetssykehus HF (hovedenhet)
Country: NO
Contract type: Supplies
Procedure: Contract award without prior publication
CPV classification: 33100000
Estimated value: 82516318 NOK
Award criteria: The most economic tender

Technical requirements: Avdeling for Medisinsk Genetikk, OUS, (the Department of Medical Genetics at Oslo University Hospital (OUS)) will procure sequencers for high throughput sequencing (HTS)/next generation sequencing, well suited to large scale exome and genomic sequencing. The department has a Novaseq, HiSeq4000 and HiSeq3000 that can be used as back-up during downtimes.
Avdeling for Medisinsk Genetikk, OUS, [the Department of Medical Genetics at Oslo University Hospital (OUS)] will procure sequencers for high throughput sequencing (HTS)/next generation sequencing, well suited to large scale exome and genomic sequencing. The department has a Novaseq, HiSeq4000 and HiSeq3000 that can be used as back-up during downtimes.
This framework agreement with contract number xxxxxxxxxx is ongoing and applies as long as at least one instrument is in use. The framework agreements include the options described in Appendix 4.1. The award of contract for consumables will follow the award of contract for the purchase of the system.
II.1) The capacity must also be high and flexible, with a sequencing output of 200 — 3000 Gb data per run;
II.2) The laboratory needs both exome and genomic sequencing for various issues. To maintain a quick response time, it is important that these can be run on the same flow cell;
II.3) It must be possible to split the instrument's flow cell so that different samples/projects can be run in parallel. In addition, it must be possible to start the instrument's flow cells at different times, independently of each other;
II.4) The requirement highlights the need for flexibility in regard to whether analysis time or capacity should be prioritised, as there will be instances where urgent samples must be processed. These will have an acceptable analysis time of 30 hours;
II.5) The instrument must be able to handle different protocols. PCR free sample preparation will be quicker (with multiple benefits), while other protocols needed can only be found PCR based;
II.6) It is very important that the sample preparation is automatic and fast. The Department has Hamilton MicroStar pipetting robots that are used for sample preparation, and therefore there must be finished validated sample preparation protocols for Hamilton MicroStar for exome and genomic sequencing. Preferably, other protocols must also be adapted to Hamilton MicroStar;
II.7) Different protocols can be optimal with different reading lengths. For a large number of analyses, longer fragments such as 250 bp will be an advantage, as this for e.g. can lead to seeing longer haplotypes, have higher sensitivity in regard to structural variation, and be advantageous to be able to separate pseudogenes from real genes. The Department also offers 16S metagenomic sequencing as a service, and for this utilises a procedure with 250 bp reads; (https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-017-0279-1). The instrument must be flexible so that short read lengths are also possible, as this will be advantageous as regards costs, and because some of the protocols will not require 250 bp read lengths. Flexibility is expected within 100-500 bp drives;
II.8) FASTQ, BAM and VCF are standard formats for the software that the department uses for analysis and interpretation of the sequencing data;
II.9) There must be instrument-compatible reagents with extra cycles (minimum 25) to allow for special analyses when required, for example, single cell libraries;
II.11) The instrument must be able to use reagents for the preparation of libraries from third party suppliers;
III. In addition, the Medical Genetics Department emphasises a need for < 48 response time from when OUS contacts the supplier until the service technician is on site.
The basis is that Illumina is the only supplier that, due to technical reasons, can deliver in accordance with the requirements. The prior information notice is founded in-line with the Public Procurement Regulations § 21-5. The terms in PPR § 13-4 (2) and 13-1 (5) are considered fulfilled, as well as the value of the full service contract and a contract for consumables for the lifetime of the equipment.


Winner: Illumina Norway AS
Award value: 82516318