Public procurement notice: Contract Notice
Published: 2022-12-23
Buyer: Public Health Institution Clinic for children diseases
Country: MK
Contract type: Supplies
Procedure: Open procedure
CPV classification: 33696500
Submission deadline: 2023-01-16
Award criteria: Lowest price

Technical requirements: procurement of apparatus and tests for metabolic screening for early diagnosis of hereditary metabolic disorders in newborns for an established method with defined reference values ​​based on a study
procurement of apparatus and tests for metabolic screening for early diagnosis of hereditary metabolic disorders in newborns for an established method with defined reference values ​​based on a study of a healthy population (newborns) from the region and for early diagnosis of hereditary metabolic disorders in neonatal and pediatric populations with comorbidities or equivalent
1.Apparatus and tests for metabolic screening for early diagnosis of hereditary metabolic disorders in newborns for an established method with defined reference values ​​based on a study of a healthy
Quaternary pump with a minimum of 4 solvents – to be connected and mixed on the instrument in any configuration at the same time
The mass tandem quadrupole detector must have a compact design so that it can be placed on a table (benchtop)
Mandatory Atmospheric Pressure Ionization Liquid Chromatography Interface (API) to include source and spray unit
A minimum of two built-in tanks for system tuning and calibration automatically included in the instrument control software. Classic syringe pumps and tuning from autosampler vials are not acceptable
In-analyzer transfer optics with double orthogonal design to reduce source contamination and separation of ion clusters formed under atmospheric pressure and for ultra-high resistance to matrix effects
Easy removal of ion source and cone elements and desolvation mechanisms for cleaning and maintenance without turning off instrument vacuum to allow maximum instrument uptime
The ion transfer interface and optics in the analyzer are not subject to routine maintenance, replacement of spare parts or cleaning of spare parts such as transfer lines or capillaries
Positive and negative ionization modes are included as standard instrument options and can be used in the same injection.
Standard ESI/APCI combined ion source (ESCi or equivalent) with a mode switching time of 20 msec maximum
The instrument must have two quadrupole mass analyzers, a collision cell, and mass prefilters to protect against contamination of the main mass analyzers and increase ion resolution with a linear geometric design.
Mandatory change from MS to MS/MS (MRM) scan mode of operation at automated optional intervals of maximum 3 msec to allow validation of methods under ion suppression and matrix effects. The Scan option should be enabled by default in the software.
The instrument should have built-in ion concentration enhancement technology in the mass analyzer to achieve additional selectivity and sensitivity for the following acquisition and scan modes:

Eligibility requirements: statement of the economic operator that in the last 5 years the economic operator or the person who is a member of the management or supervisory body of that economic operator or who has the authority to represent or make decisions or supervise him, in the last five years has not a final court verdict for a crime that has elements of criminal complicity in criminal association, corruption, tax evasion and contributions, terrorism or criminal offenses related to terrorist activities, money laundering and terrorist financing and abuse of child labor and trafficking in human beings; in the Criminal Code; - Certificate for paid taxes, contributions and other public duties from a competent authority of the country where the economic operator is registered; - confirmation that no bankruptcy procedure has been opened by a competent authority or a single document proving the ability; - confirmation that no liquidation procedure has been opened by a competent body or a single document to prove the ability; - Confirmation from the Registry of Penalties for committed criminal acts of legal entities that he has not been sentenced to a secondary penalty ban on participation in public call procedures, awarding public procurement contracts and public-private partnership contracts or a single document proving the ability; - confirmation from the Registry of fines for committed criminal acts of the legal entities that he / she has not been pronounced a secondary penalty of temporary prohibition to perform a certain activity or a single document for proving the ability; - a certificate from the Registry of Penalties for committed criminal acts of the legal entities that he / she has not been sentenced to a secondary penalty of permanent prohibition to perform a certain activity or a single document for proving the ability; - confirmation that no misdemeanor sanction has been pronounced with a final judgment - prohibition to perform a profession, activity or duty or a single document to prove the ability, and - confirmation that he / she has not been pronounced a misdemeanor sanction with a final judgment - temporary prohibition to perform a certain activity or a single document to prove the ability. In order to prove the ability to perform a professional activity, the economic operator must submit: - Certificate for registered activity as proof that it is registered as a natural or legal person for performing the activity related to the subject of procurement or proof that it belongs to an appropriate professional association in accordance with the regulations of the country where it is registered - Decision for wholesale of medical devices in accordance with the Law on Drugs and Medical Devices.