Public procurement notice: Contract Notice
Published: 2016-06-30
Buyer: Ministry of Defence, DSTL, Defence Science and Technology Laboratory (DSTL)
Country: UK
Region: Wiltshire CC
Contract type: Supplies
Procedure: Open procedure
CPV classification: 33000000 | 33600000: Pharmaceutical products | 33680000 | 71900000 | 73000000
Estimated value: 450000 GBP
Submission deadline: 2016-08-19
Award criteria: The most economic tender

Technical requirements: The requirement is for venous administration in support of clinical trials for a nerve agent antidote as an emergency therapy. The buffer will be a 10ml fill of a 100mM citrate buffer and the Placebo will be colour matched to a 100mg/ml solution of HI-6 in diluent.
Design and manufacture of a buffer for the dilution of an intra-venous (IV) administered powder filled vial of HI-6. The Placebo is required for intra-venous administration in support of clinical trials for a nerve agent antidote as an emergency therapy. The buffer will be a 10ml fill of a 100mM citrate buffer and the Placebo will be colour matched to a 100mg/ml solution of HI-6 in Diluent. The programme will be submitted to National Regulatory Agencies in the United Kingdom, Canada and The Netherlands, and consequently, the development of these sterile products must comply with all relevant quality guidelines. This includes, manufacture and preparation of drug product, stability measurements and release activities as required. The final Diluent is intended to be treated as a medicinal product for regulatory approval and the Placebo should be suitable for use in clinical trials at all phases.
The contracting authority considers that this contract may be suitable for economic operators that are small or medium enterprises (SMEs). However, any selection of tenderers will be based solely on the criteria set out for the procurement. Suppliers interested in working with the Ministry of Defence should register on the MOD Supplier Information Database (SID) Register, available at: www.contracts.mod.uk The MOD SID is a database of active and potential suppliers available to all MOD and UK Defence procurement personnel, and is the main supplier database of MOD Procurement organisations. Please note the registration and publication of a company profile on the MOD SID does not mean or imply that the supplier has in any way been vetted or approved by the MOD. Suppliers wishing to compete for advertised MOD contracts must respond to any specific call for competition by submitting a separate expression of interest in accordance with the instructions of the purchasing organisation.
From 2.4.2014, the Government is introducing its new Government Security Classifications Policy (GSC) to replace the current Government Protective Marking Scheme. A key aspect of this is the reduction in the number of security classifications used. All suppliers to the Department are encouraged to make themselves aware of the changes as it may impact on this Requirement. The link below to the Gov.uk website provides information on the new GSC.
The Authority reserves the right to amend any condition related to security of information to reflect any changes in national law or government policy. If any contract documents are accompanied by instructions on safeguarding classified information (e.g. a Security Aspects Letter), the Authority reserves the right to amend the terms of these instructions to reflect any changes in national law or government policy, whether in respect of the applicable protective marking scheme, specific protective markings given, the aspects to which any protective marking applies or otherwise.
Advertising Regime OJEU: This contract opportunity is published in the Official Journal of the European Union (OJEU), the MoD Defence Contracts Bulletin and www.contracts.mod.uk
Suppliers must read through this set of instructions and follow the process to respond to this opportunity.
You must register on this site to respond, if you are already registered you will not need to register again, simply use your existing username and password. Please note there is a password reminder link on the homepage.
The deadline for submitting your response(s) is detailed within this contract notice, you will also have visibility of the deadline date, once you have added the Access code via DCO as the opening and closing date is visible within the opportunity.
Please ensure that you allow yourself plenty of time when responding to this opportunity prior to the closing date and time, especially if you have been asked to upload documents.
If you experience any difficulties please refer to the online Frequently Asked Questions (FAQs) or the User Guides or contact the MOD DCO help desk by emailing: support@contracts.mod.uk or Telephone. 0800 282 324.

Eligibility requirements: Selection criteria as stated in the procurement documents.

Award value: 450000