TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Lymph nodes identified compared to imaging
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lymph nodes identified compared to surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in attention
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Changes in memory
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Changes in executive function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in sorbitol (mmol/mol creatinine)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in ICARS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in Antithrombin III (ATIII)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: No improvement in SOFA score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: alpha-6 integrin expression levels in leukemic blasts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Power output during time trial
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Systemic microvascular function
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum level of antioxidant enzymes protein concentration of SOD, CAT and glutathione-peroxidase
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Detection of miRNA of interest
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in HIV testing
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: occurrence of procedure specific complications
Endpoint domain: Adverse events/effects
Primary endpoint: successful retrograde puncture
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: technical success after failed antegrade approach
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Detection of pre-cervical/cervical cancer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: excellent recovery assessed by mRS score of 0-1 (%)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Minimal lumen area (MLA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in treatment satisfaction
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Rankin score at 3 months
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Time-to-first event occurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in the Severity of PTSD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Aspartate transaminase (AST)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in alanine aminotransferase (ALT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Degree of reduction of CMV and/or ADV viral load
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: quality of pain relief
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in Total Serum Immunoglobulin-G (IgG) Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum Concentration of Nipocalimab over Time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clearance (CL) of Nipocalimab
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of treatment-emergent adverse events (TEAE) ≥ grade 3
Endpoint domain: Adverse events/effects
Primary endpoint: Change of psychological well-being
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change of emotional intelligence level
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change of perceived stress level
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Incidence of hearing impairment worse than graded 2
Endpoint domain: Adverse events/effects
Primary endpoint: Change in neck functional activities
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Number of participants with Dose limiting toxicity at Dose Level 1
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with Dose limiting toxicity at Dose Level 2
Endpoint domain: Adverse events/effects
Primary endpoint: Extremity volumes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in Modified Rankin Scale
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in the 5 Times Sit to Stand Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Charge integration efficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Colorectal adenoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Clinical outcomes of diarrhoeal disease
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Clinical complete response (CCR) rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Natural Killer Cell Number
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Natural Killer Cell Number and Function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: NK Cell Function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: HRM score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of acute acoustic trauma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Delta HRV during the 6MWT
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Pulse rate changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to discontinuation of dapagliflozin
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Cerebral vascular event
Endpoint domain: Adverse events/effects
Primary endpoint: BARC 3-5 bleeding events
Endpoint domain: Adverse events/effects
Primary endpoint: Diameter of optic nerve
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Transseptal puncture success rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Change from Baseline in SF-36 Scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change from Baseline in TCU-HLTHFORM Scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change from Baseline Pain Intensity at 7 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline Pain Interference at 7 weeks
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Maximum tolerated dose (MTD) of BGB-24714
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Sensitivity and specificity of cough sound analysis to detect COVID-19
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Sensitivity and specificity of cough sound analysis to detect recent medical care for COVID-19
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequency of Deaths
Endpoint domain: Mortality/survival
Primary endpoint: Area Under the Plasma Concentration-Time Curve (AUC0-inf) of Transporter Cocktail
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Plasma Concentration-Time Curve (AUC0-inf) of Evobrutinib
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Observed Plasma Concentration (Cmax) of Transporter Cocktail
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Salivary biomarkers related to bone turnover
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Oral motor assessment scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Major Congenital Malformations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: 1-repetition maximum for strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Secondary infections in patients with HIV/AIDS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: quick SEPSIS RELATED ORGAN FAILURE ASSESSMENT (qSOFA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in protein expression profile
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage area reduction (PAR) of wounds
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Nighttime Sleep SWA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequency of moderate/severe acute exacerbation of COPD
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Seroprevalence of DENV, ZIKV, CHIKV
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Post-op opioid use
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Change in aesthetics and amount of color masking of the lesion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Urinary plasticizers levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Families' Burden
Endpoint domain: Resource use
Endpoint subdomain: Societal/carer burden
Primary endpoint: Indication of most pain relief
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Gynaecological examination gown usage
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: RPSA serum concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sum of Pain Intensity Difference (SPID0-60min)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of responder patients at 60 minutes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of Spinal Cord Ischemia Onset
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Visual Scale Self-Report Anxiety
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in chemotherapy-induced peripheral neuropathy (CIPN)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change From Baseline in Average Sleep Latency
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: rate of blood pressure reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Rate of wound area change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: mortality in intensive care unit
Endpoint domain: Mortality/survival
Primary endpoint: Late toxicity reduction
Endpoint domain: Adverse events/effects
Primary endpoint: Engagement in goal-concordant oncofertility care
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Proportion of patients receiving actionable data
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of CD Participants With PRO-2 Remission at Week 14
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Percentage of UC Participants With PRO-2 Remission at Week 14
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Spanish speaking patient satisfaction of care
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Spanish Speaking family satisfaction of care
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Overall Driving Score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: number of patients presenting with symptoms and signs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: number of patients affected with genetic mutations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: frequency of intraoperative and early postoperative embolism
Endpoint domain: Adverse events/effects
Primary endpoint: Prevalence of post traumatic stress syndrome
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Cytokine production capacity of circulating immune cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of participants recovered with clear endoscopic examination
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of accepted interventions
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Proportion of all interventions
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Preparedness for Decision Making
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Shared Decision Making (CollaboRATE-Parent version)
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Shared Decision Making (CAHPS-SDM survey)
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Shared decision making (SDM-Q-DOC version)
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Successful completion of PRDR WBRT treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Functional Health in Women
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Power to Change in Women
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Average daily pain relief score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rosenbek penetration-aspiration scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: Swallowing outcomes
Primary endpoint: Overall Neuropathy Limitation Scale (ONLS) score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Pain severity measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Initial quality of life measurement
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Thrombus resolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Detection of IBD-related microbiome-derived biomarkers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative incidence rate of ctDNA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Detrusor pressure measurement accuracy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Time to First Increase in Dependence Level Above Baseline
Endpoint domain: Life impact
Endpoint subdomain: Functional status
Primary endpoint: Adherence to the training techniques
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Treg cells frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Cytokines levels (IL-22, IL-21, IL-35, IL-33)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: AUCt of CKD-378
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax of CKD-378
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Chronic obstructive pulmonary disease severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Feasibility of sensorimotor signatures as biomarkers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Continuous CAP
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes to QTc interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Negative conversion rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Quantitative study of blood FDG:palmitate balance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Safety of NMES
Endpoint domain: Adverse events/effects
Primary endpoint: Acceptability of NMES
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Preoperative Heart Rate Variability (HRV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Completion rates of research assessments
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Lesion size after chemotherapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Modified Borg dyspnea Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: 6-minutes walk Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SATED SLEEP questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Detection of early hepatocellular carcinoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Maximum Time Sprint
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ultrasound lesion of gout
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change from baseline in mean diurnal intraocular pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent change from baseline in mean diurnal intraocular pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bacterial infection
Endpoint domain: Adverse events/effects
Primary endpoint: Cardiac decompensation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Total amount of opioid doses in 24 hours post-op
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Length of time of chest tube insertion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Assessment of improvement of tear trough
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient satisfaction of topical hyaluronic acid nanoparticles in treatment of tear trough
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Incidence of side effects of topical hyaluronic acid nanoparticles around eyes
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of recurrence leading to re-intervention
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Attendance to early cardiac rehabilitation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Drop-out of early cardiac rehabilitation
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Patient Assessment of Constipation Symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Numbers of bedside fall incidents
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Rowland Morris Disability questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Quantification of neutrophils extracellular traps
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Visual Analogue Scale (VAS) lower back pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in brachial FMD
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in cardiac function (global longitudinal strain)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of participants who experience adverse events as defined by most recent CTCAE throughout the exercise intervention
Endpoint domain: Adverse events/effects
Primary endpoint: Change in meridian energy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Global cognitive functioning (IQ)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Visuo-spatial functioning
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Number of days free from mechanical ventilation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Self-regulation of Eating Behaviour
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in State-Trait Anxiety Inventory (STAI) questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in EmBody/EmFace
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: changes in subjective response
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Ad libitum energy intake (KJ)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: non-inferiority of doxycycline compared to BPG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes