TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Change in low frequency hearing thresholds measured by pure tone audiometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Words-in-Noise Test score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Haemostatic assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change from baseline levels in pro-inflammatory circulating markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Environmental spatter produced during dental appointments
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Total Opioid Requirement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from fundamental Motor Skills
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from language development
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change from physical activity level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in daily hypoxemia burden
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Identification of TCR match
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite Dysautonomia Symptom Score (COMPASS 31)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in total score of the PROMIS 8b SD to assess sleep disturbance
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Change in sleep onset variability
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Change of psychological stress
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Proportion of screened participants that are eligible
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Proportion of enrolled participants that are randomized
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Proportion of average time delay to enrollment
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Proportion of retention among participants randomized to the Intervention Group
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Proportion of retention among participants randomized
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of participants who adhere to assigned treatment
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Soft Ball Throw Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 50 Yard Dash
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 1 Mile Run Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline of white blood cells (10^3/μL) at 3 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change from baseline of hemoglobin level (g/dL) at 3 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change from baseline of creatinine (mg/dL) at 3 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change from baseline in Quick Inventory of Depressive Symptoms
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Self-efficacy in delivering smoking cessation intervention
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Empathy in delivering smoking cessation intervention
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Lasater Clinical Judgment Rubric
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of pelvic organ prolapse
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Incidence of urinary incontinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Incidence of sexual function
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Self reported quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Fat degeneration of muscles
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: lesion clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Success rate of tissue integration of the implant
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Determination of the maximum tolerated dose (MTD)
Endpoint domain: Adverse events/effects
Primary endpoint: Interincisal opening
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clicking
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prediction of disease progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Neurovisual assessment results
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Retention at 12 weeks
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Satisfaction at intervention completion
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Satisfaction at study completion
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Area under the time-concentration curve from 0 to t hours (AUC0-t)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the time-concentration curve from 0 to infinity (AUC0-∞)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of hypoxemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in mean unmedicated diurnal Intraocular Pressure (IOP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Autism Behavior Checklist (ABC)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in passive range of motion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Time to reconstruct haematopoietic function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change in intermuscular coordination patterns
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Major Adverse events (MAE) within 30 days after procedure
Endpoint domain: Adverse events/effects
Primary endpoint: Success rate of thoracoabdominal aortic aneurysm treatment 12 months after procedure
Endpoint domain: Mortality/survival
Primary endpoint: incidence of superficial surgical site infection
Endpoint domain: Adverse events/effects
Primary endpoint: Alert according to the connected tablet
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in the Working Alliance Inventory (WAI-S)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Barriers for Adolescent Seeking Health (BASH)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Attitudes toward Psychological Help-Seeking Scale (ATPHS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Symptoms of premenstrual syndrome to reduce (PMSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Significant postoperative bleeding
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of participants achieving 75% reduction in PASI score (PASI-75)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Number of participants with treatment-emergent adverse event (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Acute change in slow-wave activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Incidence of dose limiting toxicity (DLT) events
Endpoint domain: Adverse events/effects
Primary endpoint: Percent correct monosyllabic word scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adaptive sentence in noise scores (AuSTIN)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax: maximum observed plasma concentration of Lu AF82422
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tmax: time to maximum observed concentration of Lu AF82422
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Concentration (Cmax) of IBI362
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Concentration Versus Time Curve (AUC) of IBI362
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: radKIDS Safety Knowledge
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Child Rosenberg Self-esteem Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Self-efficacy with safety skills
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Piers-Harris Self-Concept Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Walking speed on plank in virtual reality
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Distance walked on plank
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adverse events associated with psilocybin administration
Endpoint domain: Adverse events/effects
Primary endpoint: Food Record
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: General Anxiety Disorder
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Percentage of patients with SSDDS score improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Modified Medical Research Council (mMRC) Dyspnea Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Karnofsky Performance Scale (KPS)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Ongoing pregnancy rate at 12 weeks' gestation
Endpoint domain: Mortality/survival
Primary endpoint: Efficacy of NAs therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Back pain functional scale
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Postural stability by using Biodex Balance System
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax of rivaroxaban in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC0-t of rivaroxaban in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline in pain score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Usability of Quick Reference Instructions (QRI) - Critical Steps
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Usability of Test Kit
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Usability of Quick Reference Instructions (QRI) - Subject Test Result and Observer Confirmation
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Usability of Quick Reference Instructions (QRI) - Interpretation of Example Test Results
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Vowel and consonant identification
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Word recognition
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Sentence recognition
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in Beck Scale for Suicidal Ideation (SSI) scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: change of bone height around dental implants
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: change of bone density around dental implants
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Clinical characteristics of patients with spontaneous recurrent miscarriages
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Percentage of eyes with Uncorrected Distance Visual Acuity (UDVA) of 20/40 or better
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of eyes with Manifest Refractive Spherical Equivalent (MRSE) within 0.50 Diopter of intended correction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of eyes with Manifest Refractive Spherical Equivalent (MRSE) within 1.00 Diopter of intended correction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: proportion of participants treated with HST-NEETs within 1 week of ASCT
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: efficacy of HST-NEETs in reducing HIV intact proviral
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Local Tumour Control
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Clinical image quality
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SPF determination
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline DV-C levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Parental presence
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in urine albumin-to-creatinine ratio (UACR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Rate of vaginal bleeding in early pregnancy
Endpoint domain: Adverse events/effects
Primary endpoint: Risk of skin and mucous membrane contamination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Maximum tolerated dose (MTD) of NAC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Survival (OS) of patients with hormone/castration-sensitive PC
Endpoint domain: Mortality/survival
Primary endpoint: Progression-Free Survival of patients with hormone/castration-sensitive PC
Endpoint domain: Mortality/survival
Primary endpoint: Overall Response Rate of patients with hormone/castration-sensitive PC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Survival (OS) of patients with castration resistant PC treated with Luthetium-177-PSMA therapy
Endpoint domain: Mortality/survival
Primary endpoint: Progression-Free Survival (PFS) of patients with castration resistant PC treated with Luthetium-177-PSMA therapy
Endpoint domain: Mortality/survival
Primary endpoint: Area under the concentration-curve from time 0 to the last quantifiable concentration (AUClast)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in serum Indoxyl sulfate (IS) level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in visual Analog scale (VAS) score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Dermatology life quality index (DLQI)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Incidence of adverse events of CFI-402257 as a single agent
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of adverse events of CFI-402257 in combination with fulvestrant
Endpoint domain: Adverse events/effects
Primary endpoint: Neck ROM
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Community-level mean mid-upper arm circumference (MUAC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nutritional outcomes
Primary endpoint: Change in the Functional Assessment of Cancer Therapy - Breast (FACT-B)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Composite score of proportion of patients undergoing unnecessary interventions
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Health-related quality of life: general
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Health-related quality of life: brain tumor specific
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Health-related quality of life: productivity
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Health-related quality of life: medical consumption
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Percent Change in Convulsive Seizure Frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Percent Change in Major Motor Drop (MMD) Seizure Frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: IKDC-Subjective Score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Impact of vaccination campaign on immunization coverage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pathologic ablation zone
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Diagnostic value of clinical ultrasound
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Stages of Stenosing Tenosynovitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: selective attention, inhibition, and processing speed
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change From Baseline in Disease Activity Score Based on 28-joints Count with ESR (DAS28-ESR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in Functional status Based on Multidimensional Health Assessment Questionnaire (MDHAQ)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Number of Participants with Complete Response (CR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of Participants with Partial Response (PR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of Participants with Disease Progression (PD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Number of Clinically Significant Abnormal Results from Physical examinations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Clinically Significant Abnormal Results From Laboratory measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-reported negative affect
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: SAE Frequency
Endpoint domain: Adverse events/effects
Primary endpoint: Solicited systemic reaction frequency
Endpoint domain: Adverse events/effects
Primary endpoint: Prolactinotrophic effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Cerebral bleedings
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Short-form McGill Pain Questionnaire (SF-MPQ)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ototoxicity - BERA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Ototoxicity - Audiometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Differences in Cq values (qPCR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in letters read at near
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of any adverse events (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: NK cells and T cell activation subsets
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change of Movement Disorders Association, Unified Parkinson's Disease Rating Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of Balance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of Functional Reach Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Response after daratumumab treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety of daratumumab
Endpoint domain: Adverse events/effects
Primary endpoint: Methemoglobin kinetics
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Smartphone Addiction Scale - short version (SAS-SV)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Cranio-vertebral angle
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Reproductive Health Knowledge
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Complex response (CRc) rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent of approached participants who consent to study participation
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention