TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Between-day coefficient of variance (CV) for VO2 peak
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative 24-hour rescue analgesic consumption
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Peripheral Muscle Oxygenation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: change in disease activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: change in Partial Mayo Scoring Index (PMSI) assessment for Ulcerative Colitis Activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Appendicular Lean Mass
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline Depression Anxiety Stress Scale - 21 (DASS-21) scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from baseline Maslach Burnout Inventory-Educators Survey (MBI-ES) scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from baseline Stress levels
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Perception of patient
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Biopsychosocial characteristic assessment
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: PTSD screening rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PTSD diagnoses rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PTSD prescribed treatment rates
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Changes in the skin hydration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Changes in the skin glossiness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Changes in the skin firmness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Changes in the skin elasticity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Changes in the melanin content
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Changes in the proportion of crow's feet area
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Stem Migration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Social Connectedness A, Change from Baseline to Post Intervention
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Social Connectedness B, Change from Baseline to Post Intervention
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Occurrence of adverse events/reactions within 30 minutes after each dose of inoculation
Endpoint domain: Adverse events/effects
Primary endpoint: Occurrence of serious adverse events within 6 months from the first dose to the full course of vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: KDQOL-36 score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Incidence of Adverse events reaction
Endpoint domain: Adverse events/effects
Primary endpoint: Glycoprotein E(gE)-specific antibody and cell mediated immunity (CMI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serious Adverse Events (SAEs) and potential immune-mediated diseases (pIMDs)
Endpoint domain: Adverse events/effects
Primary endpoint: Muscular strength of the shoulder complex
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Abdominal-lumbar stability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total score of the Gastrointestinal Symptom Rating Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Procoagulant effect on platelet function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Changes in Ideation Severity
Endpoint domain: Adverse events/effects
Primary endpoint: Changes in Behavior
Endpoint domain: Adverse events/effects
Primary endpoint: Drooling Severity Scale (DSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Drooling Frequency Scale (DFS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Short-term response rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: interproximal clinical attachment level gain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Provider understanding of patient's visit expectations
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: motor symptoms evaluated with Hoehn and Yahr (HY) score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: motor and non motor symptoms evaluated with MDS-UPDRS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: clinical evaluation of cognitive impairment by MoCA test score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: IBD not meeting the DTT-IBD criteria
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Efficiency of induction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Brain tumor progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: motion sequences of epileptic seizures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in levels of pro-inflammatory cytokine interleukin-6
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in levels of inflammatory gene expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Information retention short-term
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in PHQ-9 Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Perceived Stress Scale Score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Morisky Treatment Adherence Scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: The World Health Organization Quality of Life Instrument, Short Form
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Bipolar Disorder Functioning Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Vital signs measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in Cellular senescence markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: local pressure pain thresholds
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative incidence of COVID-19 infection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Cmax of GBPA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUClast of GBPA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improvement of pain on the Harris Hip Score (HHS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinical evaluation of gait limping on the Harris Hip Score (HHS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Continuity of care in MOUD
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Percentage of time in target sedation range without rescue sedation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes to blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes to forearm blood flow velocity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes to plasma L-arginine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Changes to oral nitric oxide
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Changes to blood nitrate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Changes to blood peroxynitrite levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in unstimulated Salivary flow rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline on the ADHD-Rating Scale (ADHD-RS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from Baseline on the Self-Perception Profile for Children (SPPC)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change from Baseline on the Social Responsiveness Scale (SRS-2)
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Change from Baseline on the Social Skills Improvement System Rating Scales (SSIS-RS)
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Mottling incidence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mottling score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Premenstrual Symptoms
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Number of Drinking Days Per Month
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Binge Drinking Days Per Month
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Use of Sexual Violence Harm Reduction Strategies
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Infectious complication after cystectomy
Endpoint domain: Adverse events/effects
Primary endpoint: Total Adverse Reaction Incidence Rate
Endpoint domain: Adverse events/effects
Primary endpoint: Pathogen clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Average hospitalization cost per visit
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Inter-rater reliability regarding frailty
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Forced Expiratory Volume in one Second (FEV1)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Safety of tumor resection
Endpoint domain: Adverse events/effects
Primary endpoint: AUROC for PRE-DELIRIC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUROC for E-PRE-DELIRIC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of adequate cleansing of the small intestine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Percentage of eligible young adults that agree to participate in the study
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Time for recruitment
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: 1-year Event-Free Survival (EFS) rate
Endpoint domain: Mortality/survival
Primary endpoint: Tumor uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Vaping cessation rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adequacy of hyperglycemia prescription
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Consolidation of primary and periprosthetic fractures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: CARE© Score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Response Rate to CARE© questionnaires
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of adverse events or severe adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Macrovascular endothelial function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: severe nomophobia score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in overactive bladder symptom score (OABSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinically relevant complication of glucocorticoid therapy
Endpoint domain: Adverse events/effects
Primary endpoint: Value of eGFR
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change in Posner reaction times
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: change in hair thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: change in hair growth rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Volumetric measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Flank Skin Laxity Scale (FSLS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in VO2 max
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Confidence in Behavior
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Breast-feeding Self-efficacy Scale (BSS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Poor Milk Perception Scale (PMPS)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Self-Management
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Exercise Status
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Successful balloon inflation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Nursing Interns' Knowledge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Nursing Interns' performance
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Self-Instructional Module Feedback
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Time from spinal anesthesia to T10 block (min)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time from spinal anesthesia to T4 block (min)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BCI test performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Thrombus volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Device-related target vessel complications
Endpoint domain: Adverse events/effects
Primary endpoint: Drug Liking Visual Analog Scale (VAS)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change of left ventricular end-diastolic volume index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of cardiac toxicity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Accuracy of sMMG to detect respiratory effort
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: anxiety levels change
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Total pathological complete response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of Tissue healing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of biopsy-confirmed acute rejection (BPAR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Insomnia disorder incidence
Endpoint domain: Adverse events/effects
Primary endpoint: Change of insomnia symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Facial Pain Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Centimetric measurement of the thorax
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Back range of motion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Inspiratory and expiratory capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Nerve Conduction Study - Distal Latency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Rasch-built Overall Disability Scale (R-ODS) for CIDP Score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Successful dye injection
Endpoint domain: Adverse events/effects
Primary endpoint: Lung Cancer Quality of Life Scale (FACT-L)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Evaluation of tumor efficacy using RECIST criteria
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Evaluation of the severity of hirsutism
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Evaluation of biochemical indicators
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Acceptability of CAB+RPV LA implementation by patients
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Feasibility of CAB+RPV LA implementation by patients
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Acceptability of CAB+RPV LA implementation by staff
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Feasibility of CAB+RPV LA implementation by staff
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Plantar Fascia Mechanical Properties
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Freedom from all atrial tachyarrhythmias
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in quality of chest compressions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Rescuer's Fatigue
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Change in multifidus muscle size (cross-sectional area) in cm^2
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in gluteal muscle size (cross-sectional area) in cm^2
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Percent change in multifidus muscle fatty infiltration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Percent change in gluteal muscle fatty infiltration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Diagnosis of ATTRwt
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-perceived preparedness to handle vaccination concerns
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Positive Detection Accuracy (PDA) of D-Tect Patch
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: proportion of visual fixation time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Disease progression-free survival rate
Endpoint domain: Mortality/survival
Primary endpoint: Continuous Glucose Monitoring System Performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Incidence of clinically significant Adverse Events (AEs) and Serious Adverse Events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Mental health challenges
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in the Percentage of Trials That the Participant Chooses to Perform the Hard Task
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Responses Correct per Second
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean Systolic Blood Pressure Change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in empathy levels IRI
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in empathy levels EQ
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Atrial Fibrillation Knowledge Scale
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: heart function parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Non-Prescription Opioid Use
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Overdose Risk Behavior
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Pain Intensity and Interference - PEG
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Pain Interference - PROMIS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Two-years disease free survival (2y-DFS)
Endpoint domain: Mortality/survival
Primary endpoint: Levels of insulin resistance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: percentage correctly identified phonemes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Accurately Identified
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes