TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Change in the level of ingested omega-3 fatty acids
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in the level of ingested vitamin D
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in the level of ingested fibre
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Dynamic balance ability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ability to modulate brain activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: successful intubation at first attempt
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: post-induction hypotension
Endpoint domain: Adverse events/effects
Primary endpoint: labral echo homogeneity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: labral shape
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: labral hypoechoic cleft
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in anxiety levels
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Coronary re-access after TAVR procedure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: B-cell mediated disease incidence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Amount (%) of weight regain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Proportion of patients diagnosed with gestational diabetes mellitus
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Quality of information from and communication with health care professionals
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Vaginal health index score (VHIS)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: The Vulvovaginal Symptom Questionnaire (VSQ)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Day-to-Day Impact of Vaginal Aging Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Variation of Interleukin-6 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Tissue expression of HMGB1
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tissue expression of active caspase 3
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of subsequent fracture
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Resolution of CD-associated diarrhea (CDAD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Change from Baseline pelvic floor muscle strength at 6 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change from Baseline pelvic floor electrophysiology at 6 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change from Baseline pelvic floor muscle strength at 1 year postpartum
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change from Baseline pelvic floor electrophysiology at 1 year postpartum
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Onset of radiation induced mucositis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in severity of radiation induced mucositis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Agitation-Sedation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Completion of neoadjuvant chemotherapy and surgical tumor resection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Incidence of PICS and its components
Endpoint domain: Mortality/survival
Primary endpoint: Health-related quality of life (HRQoL) using EQ-5D-5L
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Cognitive Function using Montreal Cognitive Assessment (MoCA)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Time to achieve successful cannulation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Decrease of ≥ 0.5mmol/L in FPG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Decrease of ≥ 0.5 points of percentage of HbA1c
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Proportion of Participants Who Experienced a Systemic Allergic Reaction to Pfizer-BioNTech Vaccine
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of Participants Who Experienced a Systemic Allergic Reaction to Moderna Vaccine
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence rate of abnormal laboratory test results
Endpoint domain: Adverse events/effects
Primary endpoint: DLT incidence rate
Endpoint domain: Adverse events/effects
Primary endpoint: Engraftment of donor microbiota
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in microbiome characteristics over time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Amount of cfDNA/NETs in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in UPDRS-III
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: NPPV subjective tolerance
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Pain Relief by Visual Analogue Scale (VAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Activities of daily living by Neck Disability Index (NDI)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Cervical Compression Test by Spurling's Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Major Pathological Response (MPR) rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of genetic testing by 6 months
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Efficacy of analgesia using FLACC Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Threshold sensitivity values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of the ABI-effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants with left ventricular systolic dysfunction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Pharmacokinetics of 1-hydroxymidazolam
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence to oral medication
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Concentration of excreted thymine dimers in urine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 1-year ADT-free survival
Endpoint domain: Mortality/survival
Primary endpoint: Probability of Radiotherapy-related Toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: Static and Dynamic Postural Stability Tests
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Risk of delaying antibiotic therapy
Endpoint domain: Adverse events/effects
Primary endpoint: Pain assessment using algometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Spinal mobility measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pathological complete response (pCR) rate
Endpoint domain: Mortality/survival
Primary endpoint: postoperative rebleeding rate
Endpoint domain: Adverse events/effects
Primary endpoint: Correct inhaler technique 30 days post discharge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reach of the TELE-TOC intervention
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Mean serum vitamin D
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Six Minute Walk Test Distance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: IL-6 Levels 24 Hours After Vaccine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: IL-10 Levels 24 Hours After Vaccine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: TNF-alpha Levels 24 Hours After Vaccine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: IFN-gamma Levels 24 Hours After Vaccine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Severe (grade 3+) adverse effects
Endpoint domain: Adverse events/effects
Primary endpoint: systolic blood pressure (mmHg)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Heart rate (heart beats per minute)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes in unmet needs
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Cosmetic appearance of the breast
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Pain minimization during urethral catheterization and cystoscopy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Neurotransmitter Concentration Fluctuation in Visual Memory
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Neurotransmitter Concentration Fluctuation and Pupillary Diameter in Sustained Attention Tasks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Neurotransmitter Concentration Fluctuation in Neuroeconomics Tasks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: CHWs' satisfaction
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Palm grip strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 5 SIT TO STAND
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in fraction of exhaled nitric oxide (FeNo)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Radiation dose to target volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Radiation dose to left lung
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Radiation dose to heart
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: cumulative live birth per IVF cycle
Endpoint domain: Mortality/survival
Primary endpoint: NASA Task Load Index (NASA-TLX)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Plaque size estimation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Plaque progression estimate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Ionized magnesium levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Skeletal Muscle Contractile Properties
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in self-reported medication adherence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in self-reported health-related quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in self-reported beliefs about medicines
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improvement in therapeutic adhesion
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Parent FCR attendance
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of participants with abnormal laboratory
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in overall mean satisfaction score of NDPOQ
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Overall mean score of perceived impact section from uMARS
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Overall mean score of HSUS
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Digestive quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: GDMT score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence rate of Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of successful completion of TORS without conversion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Recruitment Pace
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Retention Percent
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Anti-transglutaminase-IgA titer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: chair-stand test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 12-item MS walking scale (MSWS-12)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Rate of Perceived Exertion
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: early disease response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Lenses With Axis Orientation Within Plus or Minus 30 Degrees
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anatomical reproductibility of the dental impression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quality of care
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Occurrence of adherent perinephric fat
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of infants with type 1 or 2 ROP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Amplitude of median nerve dermatomal somatosensory evoked potential
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Distal Latency of median nerve dermatomal somatosensory evoked potential
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Pain Pressure Threshold on upper trapezius
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Hand grip Strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Level of radiating pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Count of Gatekeeper Behaviors Used
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Demonstrating a Significant Clinically Meaningful Response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction of ICP below treatment threshold
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-operative pain at 24 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-operative pain at 48 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anxiety measurement
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Time to bladder reaching large, ovoid shape
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Area Under the Concentration-Time Curve (AUC[0-inf])
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC from Time 0 to time of the last measurable concentration (AUClast)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Receipt of sexually transmitted infection (STI) testing in the past three months
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Colonization of the gut by aerobic Gram negative rods and yeasts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: LAD Pulsatility index (PI) modification
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Health and Appearance of the Skin in the Periorbital Area
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Average change in intraocular pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants with Clinically-driven Target Lesion Re-intervened
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Status Anxiety Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from baseline in morning serum androstenedione (A4)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change in Carer Burden Scale mean score
Endpoint domain: Life impact
Endpoint subdomain: Societal/carer burden
Primary endpoint: Proportion of participants without treatment failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Concentration of platelet activation markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Percentage of Participants Achieving ≥ 1 Stage Improvement in Histological Fibrosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Percentage of Participants Achieving NASH Resolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Change of cognitive functioning in elderly without intellectual disability
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change of cognitive functioning in persons with intellectual disability
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: hypopharyngeal mean peak pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of subjects with fracture healing
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change from Baseline in Five times sit-to-stand time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in Patient-Reported Outcomes Measurement Information System (PROMIS) - Physical Function
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change from Baseline in Quiet unstable sitting test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Slope of change in dentate nuclei magnetic susceptibility
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Slope of change in dentate volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Slope of change in total cerebellar volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Discontinuing From Study Therapy Due to AE
Endpoint domain: Adverse events/effects
Primary endpoint: change in the secretion of IL-17 from activated CD4+ T cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Endocan blood levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Response based on Facial Vitiligo Area Scoring Index 75 (F-VASI75) at Week 52
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Smell Threshold, Identification and Discrimination (TDI score)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum pain score on Post-operative day 30
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Consumption of daily morphine equivalents 3 days post operatively
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Consumption of daily morphine equivalents 3 months post operatively
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to Loss of Efficacy or pain recurrence
Endpoint domain: Adverse events/effects
Primary endpoint: Type, frequency, severity, and attribution of AEs/SAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Sortilin (ng/ml)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: LDL (mg/dl)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in collagen probe uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: DHEAS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Insulin-mediated eNOS phosphorylation at 6 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Insulin-mediated eNOS phosphorylation at 14 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Percent change in wrinkle severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of Patients Experiencing at Least One Clinically Significant Event (CSE)
Endpoint domain: Adverse events/effects