TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Normalization of lean volume of the gallbladder
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Complete resolution of BS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: rate of successful DRA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of asymptomatic cerebral micro-thromboembolism
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of hemopericardium
Endpoint domain: Adverse events/effects
Primary endpoint: Positivity rate of DuCV
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Median infarct volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mRS score distribution
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative incidence of AMI
Endpoint domain: Mortality/survival
Primary endpoint: Inconsistent condom use
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Risk of pregnancy and STI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: AUC of the combined nomogram model
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of premature delivery
Endpoint domain: Adverse events/effects
Primary endpoint: Compulsory hospital admissions
Endpoint domain: Mortality/survival
Primary endpoint: Self-perceived symptoms
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Recovery score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: average deviation distance of K-wire placement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: average deviation distance of pedicle screw placement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Effectiveness
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: modified Rankin Scale score of 0-1 at 90 days
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: any intracranial hemorrhage within 22-36 h
Endpoint domain: Adverse events/effects
Primary endpoint: Plasma concentration-time profiles of empagliflozin and lobeglitazone
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tolerability of treatment groups
Endpoint domain: Adverse events/effects
Primary endpoint: slowed disease progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improvements in motor symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improvements in behavioral symptoms
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: NICU mortality risk
Endpoint domain: Mortality/survival
Primary endpoint: Increase in MoCA score by 2 or more points
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: 1-km performance time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Disruption of connectivity in striato-cortical networks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: ability of walking at the BPI-I
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Oxford staining scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Unplanned intubations
Endpoint domain: Adverse events/effects
Primary endpoint: mean percentage of online lunch items per student that were 'Everyday'
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean percentage of online lunch items per student that were 'Should not be sold'
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Word recognition in quiet
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Signal-to-noise ratio improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: decreased uncertainty
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Nighttime diary-rated VMS frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Average 4-week ISI within-person decrease from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time taken for suturing task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: LS-CAT score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: E/E' ratio (diastolic function)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Ratings of letter clarity
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Incidence of Clostridium difficile infections (CDI)
Endpoint domain: Adverse events/effects
Primary endpoint: hCG-detected pregnancies
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: pregnancy losses
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: viability of microbial cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: vitality of biofilms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: healing after laser ablation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Higher functioning after treatment
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Reduction in anxiety, depression, and insomnia symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Positive effects on Parkinson-specific function
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: clinico-histological remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean peak eosinophil counts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: deep endoscopic remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: exposure to fluoroscopy
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Average symptom severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: two-year rate of death or HFH
Endpoint domain: Mortality/survival
Primary endpoint: improving survival
Endpoint domain: Mortality/survival
Primary endpoint: overall score of sexual function
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Knee pain on the first night after surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Daytime pain in the thigh at 2 weeks after TKA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: D-dimer level 3 months after TKA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Rate of major coronary evaginations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Development of a thin homogeneous neointimal layer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: CVAI improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Parental perception of cranial changes
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: ΔCRQ-D
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: visual retrograde memory
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: retrograde memory side-effects
Endpoint domain: Adverse events/effects
Primary endpoint: Overall accuracy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Sensitivity for distinguishing nodules
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Sensitivity for distinguishing malignancy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Strength-root mean square (biceps brachii, triceps brachii, flexor digitorum)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: EQ5D overall health score one year after surgery
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: EORTC‐QLQ‐C30 overall health score one year postoperatively
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: mean changes in dystrophin expression (% normal)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean exon 53 skipping level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in frequency of vessel segments with severe inflammation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvements in visceral fat
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Physical component SF-36
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: monocular acuity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: interocular acuity differences
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fracture-related infection and nonunion
Endpoint domain: Adverse events/effects
Primary endpoint: Composite primary events
Endpoint domain: Mortality/survival
Primary endpoint: Serum artepillin C levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Harm perceptions
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: AUC0-∞ of abiraterone
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax of abiraterone
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bioavailability of N-AbA 300 mg
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: nutrition-related attitudes
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: preferences
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: overall vegetable behavior score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: length of stay (LOS)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: HAMD-24 score reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Responder rates for HAMD-24 scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to LOC (MOAA/S score ≤ 1)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of haemodynamic events
Endpoint domain: Adverse events/effects
Primary endpoint: Increased diversity of bacterial species
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Global health status/quality of life scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Time to deterioration for pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to deterioration for dysphagia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: delirium
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Cumulative time of hypotension
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of individuals delivering within 24 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: enhancement of motor cortical excitability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: composite endpoint occurrence
Endpoint domain: Mortality/survival
Primary endpoint: Quality-of-life dimension of joint damage perception
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Perceived functional abilities (lying/sitting/kneeling/standing)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Perceived functional abilities (complex lower extremities activities)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: ALN tumor burden
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: ETDRS letter score at 1 year
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: health and wellbeing improvement
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: mental health response
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Pain reduction during childbirth
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Anticipatory anhedonia
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: General depression symptoms
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Cue‐P3 amplitude during MID reward trials
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: creativity measurements
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Adherence to recommended annual follow-up eye care
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Balance improvement (Mini-BEST test)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Response rate (≥50% reduction from baseline in MMDs)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increase in α and β waves
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Reduction in audio-reaction time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Reduction in choice-based visual-reaction time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Patients achieving TO
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sustained clinical improvement rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: meropenem AUC0-24 h in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: meropenem AUC0-24 h in ELF
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Receipt of timely treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 90-day stent patency rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: median duration of stent patency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hope supporting elements of ACP conversations
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Reduction in immediate antibiotic prescriptions
Endpoint domain: Adverse events/effects
Primary endpoint: Improved glucose levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Hoogland score of 4 (active follicle-like structures)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Absence of COC withdrawal bleeding
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Fertility knowledge gains
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intentions to optimize behaviours
Endpoint domain: Life impact
Endpoint subdomain: null
Primary endpoint: Chronic kidney disease risk
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: physical and psychological capacities
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Screening participation rate
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: femoral neck aBMD change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: total hip aBMD change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: adverse reproductive health outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Risk of CSFL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 6MWD z-score improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic performance in differentiating AIS/MIA from IAC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient satisfaction with anesthetic technique
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Facilitation of sequential reaching task
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean consumption of additional analgesic drugs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Physiological and behavioral instability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: subcutaneous fat percentage change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: visceral fat percentage change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: liver fat percentage change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: pancreatic fat percentage change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: average increase in tPSA after exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total per patient cost
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: OCD severity reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in overvalued ideation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain-free ratings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall headache relief
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Progression within 6 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: distal siVaw improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: total SCORAD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: POEM
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: SA colonization status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: OPTION5 score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: quality of life (MLwHFQ)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: time to ≥50% decline in eGFR
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: development of end stage renal disease (ESRD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Retention rates at 3 and 6 months
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: learning gain in strategic knowledge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: extraneous cognitive load
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Mean hyperopic shift of TCRP
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Posterior corneal curvature (Km) steepening
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in fine motor control
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Return to pre-dystonia performance levels
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Biomechanical characteristics restoration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mobility of operated teeth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Annualized rate of moderate to severe COPD exacerbations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Lung function (FEV1, FVC, RV, and TLC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Quality of life (SGRQ-C and CAT)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Image quality of 640-slice CT scan
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Effective radiation dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Stabilometric platform measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Days spent with delirium
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of participants excluded due to SWEDD status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Full-mouth plaque reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequency of alanine transaminase or aspartate transaminase >3× upper limit of normal
Endpoint domain: Adverse events/effects