TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Change from Baseline in Forced Expiratory Volume in 1 second (FEV1) to 6 hours postdose on Day 1 in Part B
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in levels of IgA1 O-glycosylation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Attendance in Treatment
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Provider Rated Engagement
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: International Myositis And Clinical Studies group-Total Improvement Score (IMACS-TIS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline Pain Assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Concordance with PGT
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Success rate (first pass success) with Video laryngoscope with Macintosh blade C-MAC
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Success rate (first pass success) with hyperangulated video laryngoscope D-BLADE
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Success rate (first pass success) with Conventional laryngoscope
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Success rate (first pass success) with Surgical airway protection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Success rate (first pass success) with Bougie/tube introducer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Change in PROMIS Pain Interference
Endpoint domain: Life impact
Endpoint subdomain: Pain
Primary endpoint: Change in Average Daily Step Count
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change in Sleep-Wake Cycling Maturity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in length of time spent in sleep
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in the number of awakenings in a 3 hour time period
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Whole Brain Butyrate PET Radiotracer Binding
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Size of the latent intact proviral HIV reservoir in cell-associated HIV DNA (Ca-DNA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Size of the latent defective proviral HIV reservoir in cell-associated HIV DNA (Ca-DNA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: blood MAIT cells frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Clinical Complete Remission Rate (CRR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: cough symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in GACAT performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Circumference measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bioimpedance spectroscopy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: VAS (Visual Analog Scale) Pain
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Surgical complications graded as Accordion grade 3 or more
Endpoint domain: Adverse events/effects
Primary endpoint: American Society of Anesthesiologists (ASA) physical status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Premenstrual syndrome assessment scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Premenstrual syndrome specific life satisfaction scale
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: DAS depression stress anxiety assessment scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Fatigue evaluation
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Number of patients with immediate infusion reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Development of Acute graft versus host disease (GvHD)
Endpoint domain: Adverse events/effects
Primary endpoint: Risk for chronic GVHD
Endpoint domain: Adverse events/effects
Primary endpoint: Number of scans to gain competency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Psychological assessment outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of wound area reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Alveolar ridge dimension changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Macrovascular function (Flow mediated dilatation%)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Mechanical evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in macrovascular function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in central arterial stiffness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: longitudinal change in the S/F
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean change on the Montgomery-Åsberg Depression Rating Scale (MADRS) total score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Rate of first-attempt tracheal intubation success
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: SF-12 (Quality of Life)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Plasma concentrations of ZSP1273
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ankle radiographic angles
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Severity of Lupus Nephritis in participants
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: 36-Item Short Form Health Survey (SF-36) total score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Tolerability assessment by evaluation of the number of subjects who will not withdraw prematurely from the study
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Change in hazardous drinking
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in frequency of alcohol-opioid co-use
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Average of Home Blood Pressure Values
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Variation in tidal volume distribution
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Intracranial Objective Response Rate (IC-ORR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Number of Lesions With Technical Success
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Prevalence of work related musculoskeletal disorders
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Annualized Aggregate Relapse Rate (ARR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Gait Outcome Assessment List-(GOAL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Complete sensory femoral nerve block
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Improvement in quality of life (EORTC QLQ - BM22)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Improvement in quality of life (EORTC QLQ-C15-PAL questionnaire)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change from Baseline in IKDC
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Total Number of Emergency Department Visits
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Cost to Medicaid for all Emergency Department Visits
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Knee flexion moment impulse
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cartilage T2 relaxation time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite of all-cause mortality or heart failure hospitalization
Endpoint domain: Mortality/survival
Primary endpoint: Mean overnight transcutaneous carbon dioxide
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Proportion of cancer patients with a venous thromboembolic event (VTE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Rate of local and systemic reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Biological monitoring of blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Proportion of pregnant women seen in antenatal care who are tested for HIV and syphilis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Proportion of HIV-positive pregnant women seen in antenatal care who are on antiretroviral therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Proportion of HIV-exposed infants seen in antenatal care who are tested for HIV by 6 weeks of age
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Case fatality rate per 1,000 HIV-exposed neonates admitted to Sally Mugabe Central Hospital
Endpoint domain: Mortality/survival
Primary endpoint: MPR rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Lesion margins
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lesion internal enhancement pattern
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Treatment-Related Mortality Rates
Endpoint domain: Mortality/survival
Primary endpoint: Incidence of sarcopenia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in language composite outcome
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Executive Composite Outcome
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Global Cognitive Scores
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Frequency of PRN intravesical administrations
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of Patient Mortalities (48 hours)
Endpoint domain: Mortality/survival
Primary endpoint: Number of Major Bleeding Occurrences
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Mean Pulmonary Arterial Pressure (mmHg)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Efficacy of ST-100 Ophthalmic Solution measured by Schirmer's test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Completion of serial blood and ePRO collections
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Concentration above the minimum inhibitory concentration (MIC) ≥ 50 % of the time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Kofoed Ankle Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of major or clinically relevant non-major bleeding events
Endpoint domain: Adverse events/effects
Primary endpoint: Mean Change From Baseline in Total Nasal Symptom Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety and tolerability of treatment with si-544
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of patients initiating TPT
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Retention of enrolled patients
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: IBS-Symptom Severity Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of total antibodies to AAV8
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Occurrence of neutralizing antibodies to AAV8
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Geometric mean titers (GMT) of IgG antibody
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Geometric mean titers (GMT) of HBGA blocking antibody
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in Focal Cerebral Arteriopathy Severity Score (FCASS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change from baseline in TMH
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequency of polycystic ovary syndrome
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: 20km cycling timetrial performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Foot temperature measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Residual Volume at 1st Flow-stop
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of revision procedures
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: duration of i.v. antibiotics application
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in material characteristics
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total recovery of radioactivity in urine, feces, and total excreta
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Columbia-Suicide Severity Rating Scale (C-SSRS) Response
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Percent Change from Baseline in Observed Countable Motor Seizure Frequency (per 28 Days) During the Treatment Period
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Mean change in alpha diversity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diet specific changes in secondary bile acids
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Diet-specific changes in inflammatory marker
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Hair follicle survival rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peripheral inflammatory status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in NRS score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximal Exercise Performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sub-maximal Exercise Performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fatiguing Isometric Exercise Performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Types of complications in neglected inhaled foreign body
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of participants with Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Change from Baseline Weight at 4 Months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change from Baseline Body Mass Index (BMI) at 4 Months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change from Baseline Health-Related Well-being at 4 Months
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Outcome of Cardiac patients admitted to PICU
Endpoint domain: Mortality/survival
Primary endpoint: Percentage of Participants With Antibody Titers >=1:8 Against Meningococcal Serogroups A, C, W, and Y
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Percentage of Participants With CR
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic accuracy of sonographic venous Doppler imaging
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Science motivation
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Science identity
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Ferritin difference
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Rates of blood transfusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Annualized Rate of Moderate and Severe COPD Exacerbations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Child's Emotional and Behavioural Symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: clinical overall response rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Anxiety Severity and Impairment Scale change
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Investigator-Confirmed Progression-Free Survival (PFS)
Endpoint domain: Mortality/survival
Primary endpoint: Change in serum d-dimer levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Detection of SARS-CoV-2 on nasopharyngeal samples
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Detection of SARS-CoV-2 on saliva samples by mass spectrometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: International Knee Documentation Committee (IKDC) Subjective Measure
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Patient-Reported Outcomes Measurement Information System (PROMIS) Global-10
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: McMurray Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ad-libitum meal consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Blood HbA1C %
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: The Diabetes self-management score using the (DSMQ)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in BSA score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change in DLQI score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Incidence of hard embolic adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of hard arrhythmic adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Fluctuation pattern of spirometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Fluctuation pattern of FeNO
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Fluctuation pattern of IOS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Treatment success with biological
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: trend of Asthma Control Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: trend of Asthma Quality of Life Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Number of patients completing the ERCP procedure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Fluctuation of Intraocular pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of Uterine contractions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Measure of variation of incontinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Measure of variation of urinary urgency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Vaccine titers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bystander (local) tumor response rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Reference interval for hormone therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anxiolysis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: American Orthopaedic Foot and Ankle Society scores (AOFAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Degree of lower esophageal sphincter contraction and relaxation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Collagen content in muscle biopsy specimens
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes