TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Recruitment, completion, and retention rates of participants
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Acceptability according to the Theoretical Framework of Acceptability
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Non-Motor Symptoms Scale, Second Version (NMSS-2)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Incidence of ambulatory systolic blood pressure (BP) > 140 or diastolic > 90
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Need for new or escalated anti-hypertensive medication
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Incidence of moderate-to-severe atherosclerosis of major coronary vessels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Body weight percent change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean change in Alzheimer's Disease Assessment Scale score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Opioid Use Within 24 Hours After Chest Tube Removal
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: BHS-6 score difference
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: C-SSRS score difference
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: NCCN Distress Thermometer score difference
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: MDADI score difference
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: FACT-H&N (Version 4) score difference
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Efficacy of VERU-111
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Weight bearing tolerance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time-frequency characteristics of EEG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Collagen protein synthesis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to onset of serious adverse events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Time to resolution of AEs
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Body Weight Percent
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Activity Completion
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Proportion of participants who experienced 1 or more treatment-emergent AEs
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of participants who discontinued study medication due to an AE
Endpoint domain: Adverse events/effects
Primary endpoint: Probability of successes in patients receiving the combination therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of treatment-emergent events (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Change in the Fugl-Meyer Upper Arm Assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Change in the Action Research Arm Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Change in the Modified Rankin Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Change in general OCD literacy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in stigmatizing attitudes related to OCD associated with a vignette
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Change in comfort in addressing OCD
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Number of Participants with Solicited Injection Site Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants with Immediate AEs Following Vaccinations
Endpoint domain: Adverse events/effects
Primary endpoint: Concentration of dupilumab in serum
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Radiographic Global Impression of Change (RGI-C) Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of treatment-related adverse events leading to study drug discontinuation
Endpoint domain: Adverse events/effects
Primary endpoint: HCPs' knowledge and understanding of hyperglycemia management
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Identification of Complement Factor I Deficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of mast cell activation symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Plasma Concentration-time Curve from Time Zero to Time t (AUC0-t) of Tavapadon
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Child's functional level
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Proportion of AGYW with a sexually-transmitted infection (STI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Proportion of AGYW who complete HIV testing and counseling (HTC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Proportion of AGYW who elect to take pre-exposure prophylaxis (PrEP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Penile oxygen pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: HPV self-sampling return rate
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Proportion of HPVss-positive women well managed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cost and cost-efficacy
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Incidence of Dose-limiting toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: Numbers of subjects with adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Lesion Patency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: mHealth Application Usability
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Functional Movement Disorder Rating
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Poor cardiorespiratory fitness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Desquamation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Irritation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Percent of change in plaque vulnerability parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Assessment of Inspiratory Pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Assessment of Hand Grip Measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Efficacy of treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Headache Pain Freedom
Endpoint domain: Life impact
Endpoint subdomain: Pain
Primary endpoint: Immunogenic Cell Death induced by tumor cryoablation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Patient's Perceptions of Physician Empathy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Leakage Episodes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ocular Alignment at Distant Fixation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ocular Alignment at Near Fixation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Achieving ACR50 and Weight Reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Boston Carpal Tunnel Syndrome Questionnaire Symptom Severity Scale (BCTQ-SSS)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Quick Disabilities of the Arm, Shoulder, and Hand Questionnaire (Quick-DASH)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Boston Carpal Tunnel Syndrome Questionnaire Functional Status Scale (BCTQ-FSS)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change in Erectile Function
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC[0-∞] of ADC-189
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax of ADC-189
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of patients completing post-treatment audiogram
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intraoperative parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intervention adherence
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Aggressiveness of care near the end of life
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Habitual physical activity
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: change in electrical impedance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: duration of CPAP treatment
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Accuracy of transcutaneous laryngeal US
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Variation in the level of mindful eating
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Functional patient-reported outcome
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Number of Treatment-related Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of subjects that complete the study
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Diagnostic accuracy detecting residual fragments
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: severity of chest pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: level of anxiety and depression
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Enhanced Liver Fibrosis (ELF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Coagulation Index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change of pain intensity during migraine attacks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anabolic response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AT-EOS content
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Percentage of participants achieving SRI-4 response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Immunological response measured by differentials of innate immune cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Severity of influenza
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Percentage of patients with complete ctDNA clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duration of ctDNA clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 50% ctDNA clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of water-related injuries
Endpoint domain: Adverse events/effects
Primary endpoint: Time to first occurrence of composite cardiovascular outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Resolution of Irritable Bowel Syndrome
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Abdominal Pain Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Stool Form Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Mayo Bloating Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Distribution of 68Ga-FAPI-JNU in tumors and normal tissues
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Forearm glucose net balance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Achievement of complete closure of the target PG ulcer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Emotional Exhaustion Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: 68Ga-Galmydar PET/CT uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diabetic ketoacidosis events
Endpoint domain: Adverse events/effects
Primary endpoint: Change in CGM-measured time in range (70-180 mg/dL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Brief Symptom Measure
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Concentration of serum Neurofilament Light
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: percentage of change in Online surveys Response Rate
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Metastasis-Free Survival (MRFS)
Endpoint domain: Mortality/survival
Primary endpoint: Accuracy of Ada WRA and HDA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Comprehensiveness of Ada WRA and HDA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement of students' knowledge
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Adaptive healthy measures
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Attitude regarding PCOS
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Time to negative viral nucleic acid detection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Mallet grading system
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fear of Falling Avoidance Behavior
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from baseline in Mucositis Grade
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline in Xerostomia Grade
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: High emotional exhaustion
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: High depersonalization
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Performance score on OSCE
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Change in resuscitation performance retention score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total relief of dental crowding
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Level of agreement for heart rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of >=Grade 3 toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of Technical Success of the Rivet Shunt Implantation Procedure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Reduction of avoidable procedures
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: NAD+ and NADH concentrations in whole blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Blood cell indicators (red blood cells, white blood cells, platelets)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Blood biochemical indicators (liver function, blood lipids, blood sugar, renal function, uric acid, lactate dehydrogenase, creatine kinase)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peripheral blood immune cell phenotype
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Keratitis lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adoption of recommended diet and exercise behavior
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: therapeutic efficacy in depression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Knowledge about TECW
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Accuracy of Loss of Residence measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mitral stenosis severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Mitral stenosis scoring
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Proportion of patients without Post-traumatic stress disorder
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: alpha and beta diversity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: change in retinal oedema
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Performance Evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Efficacy Evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes of macular choroidal thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility of Real-Time Gated 4DCT
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Depth of hypovitaminosis D
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: post-operative intraocular pressure (IOP) reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Symptomatic SARS-COV-2 infections
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: COVID-19 hospitalizations and severe cases
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Survival Outcomes
Endpoint domain: Mortality/survival
Primary endpoint: Root mean square of successive RR interval differences [RMSSD]
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Cholesterol Esterification Percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: 17-OH Progesterone Level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change in hand functional activities
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in maximum grip strength without TS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in maximum grip strength with TS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change on the Mobile Continuous Performance Task (CPT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: baseline blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Second visit blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: baseline heart Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Second visit heart Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: baseline muscle sympathetic nerve activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Second visit muscle sympathetic nerve activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Self-declared abstinence
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: change in sperm volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: change in sperm morphology
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: change in sperm concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Change From Baseline in the Modified Unified Multiple System Atrophy Rating Scale (UMSARS) Part I Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: McGill Core Endurance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in joint function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in Massachusetts General Hospital Rumination Questionnaire (MGH-RQ)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing