TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Distance between the cusps of canines (conventional technique)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anti-Mullerian hormone (AMH) serum level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: prevalence of hepatic steatosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Post-treatment pain assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Appearance of edemas, blisters, bubbles or scars
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Skin color evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: adverse event (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: serious adverse event (SAE)
Endpoint domain: Adverse events/effects
Primary endpoint: Generalization of cognitive effects
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Young Mania rating scale scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Biological Rhythm Interview Evaluation scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hamilton Depression rating scale scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Participant Adherence to TENS
Endpoint domain: Life impact
Endpoint subdomain: Other resource use
Primary endpoint: Safety outcome measures (SAEs, AEs, and local and systemic reactogenicity)
Endpoint domain: Adverse events/effects
Primary endpoint: Rates of Readmissions
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Rates of Emergency Department Visit
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Rates of Referrals to Homecare
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Reaction time of the Emotional Stop Signal (SSRT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Wound healing within 7 days post-operation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Retention rate associated with study completion
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Compliance with study dosing regimen (VAS-D)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Compliance with study dosing regimen (quantity of unused product)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Safety of ECE50
Endpoint domain: Adverse events/effects
Primary endpoint: Performance of ECE50
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occult breast cancer frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Radiographic union rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Clinical union rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Proportion of Participants With Severe COVID-19
Endpoint domain: Adverse events/effects
Primary endpoint: Cycline D1 expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Professional Quality of Life (ProQOL)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Late Life Function and Disability Instrument (LLFDI)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Step Count
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: availability of saphenous trunks as possible grafts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Change in high-sensitivity cardiac Troponin levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes in peri-implant keratinized mucosa width
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in total score of the Paediatric Quality of Life Inventory Version 4.0 (PedsQL™)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: CGM accuracy - fingerstick values
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: CGM accuracy - serum and arterial glucose values
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Percentage of Participants in Cohort 1 Achieving Clinical Remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Who Discontinued Due to an AE
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants Who Had One or More Serious Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with adverse events (AEs), serious adverse events (SAEs), and withdrawals due to AEs
Endpoint domain: Adverse events/effects
Primary endpoint: Maximum reduction of serum HBsAg levels from Baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants achieving complete response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Any adverse reaction that results in a clinical decision to stop immunisations
Endpoint domain: Adverse events/effects
Primary endpoint: Total IgG Binding antibody response rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of Participants With Serious Adverse Events (SAEs) and Treatment Emergent Adverse Events (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Maximum Tolerated Dose (MTD) and Recommended Phase II Dose (RP2D)
Endpoint domain: Adverse events/effects
Primary endpoint: Borg Rating of Perceived Exertion (RPE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall response rate (ORR: CR+PR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility Retention Rate
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Change from Baseline Brief Pain Inventory (BPI) Interference Scale
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Change from Baseline Patient Health Questionnaire (PHQ)-8
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Graft Retention on Slit Lamp Examination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Incidence of Post-operative Adverse Events Requiring Treatment
Endpoint domain: Adverse events/effects
Primary endpoint: Average drop in SpO2 from baseline to nadir
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Pulmonary Regurgitation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Spinal H-reflex excitability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Post-Concussion Symptom Severity Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Chronic success
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite Complete Remission (CRc)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Change in Severity of Adolescent Depressive Symptoms, Self-report
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Severity of Adolescent Depressive Symptoms, Parent-report
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Persistence of donor NK cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum retinyl ester area-under-the-effect-curve
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Hair Doxycycline Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma Doxycycline Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Urine Doxycycline Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Free and Cued Selective Reminding Test (FCSRT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Diagnostic performance for detection of glaucoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ophthalmic outcomes
Primary endpoint: hepatocellular carcinoma recurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Durability of effect on HBV parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Gastrointestinal Symptom Rating Scale (GSRS) Total Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Forced expiratory volume in 1 second (FEV1) Decline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: real world time to the next treatment or death
Endpoint domain: Mortality/survival
Primary endpoint: Incidence of TESAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Overall Response Rate (ORR) by mRECIST
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Gastric Cancer Development
Endpoint domain: Mortality/survival
Primary endpoint: Change in Gut Microbiome Diversity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Change in Oral Microbiome Diversity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: 3-years Overall Survival Rate
Endpoint domain: Mortality/survival
Primary endpoint: straight leg test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: sit and reach test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: finger-ground distance measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Ultrasonography
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Demonstrated Skill Score in communication skills
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: sensitivity of the i-ROP DL system
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: specificity of the i-ROP DL system
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Return to Work/Functional Activity
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Rate of Participant Recruitment
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Rate of Participant Engagement with Patient Navigator
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Rate of Participant Engagement with PainTrainer
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: 30-day net adverse clinical event (NACE)
Endpoint domain: Adverse events/effects
Primary endpoint: Collection of daily urine samples
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Human Mass Balance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of biochemical leak or fistula after pancreatectomy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Global Clinical Impression - Severity Scale (CGI-S)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Hernia Recurrence Rates
Endpoint domain: Adverse events/effects
Primary endpoint: Morningness-Eveningness Questionnaire (MEQ)
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Pregnancy-Unique Quantification of Emesis and Nausea (PUQE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Oral Glucose Tolerance Testing (OGTT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Incidence of Safety Outcomes
Endpoint domain: Adverse events/effects
Primary endpoint: Amount of anesthesia waste generated per surgical case
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Days of first flatus
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Post op nausea vomiting
Endpoint domain: Adverse events/effects
Primary endpoint: Blood glucose excursion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: ED visit rates at 12 months
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: patient reported sense of mastery
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Mean Inter-trial Coherence (ITC) Magnitude of 40 Hz-derived Auditory Steady-state Response (ASSR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Reduction in severity of psoriasis by 75% (PASI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Reduction in severity of psoriasis by at least 2 points (sPGA score)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: wound size measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Daily PTSD symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Virus-specific antibodies levels in serum
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Frequencies and numbers of circulating T cell subsets, B cell subsets, dendritic cells, NK cells in peripheral blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Levels of antigen-specific IgE and IgG4, IFN-γ, IL-4, IL-5, IL-10, IL-17A, and IL-21 in serum
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Positive conversion rate of specific IgG antibodies by serotype
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Occurrence of Dose-Limiting Toxicities (DLT)
Endpoint domain: Adverse events/effects
Primary endpoint: Kidney transplant rejection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Efficiency (ETDRS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Utility of RWD matching report
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Utility of the IMC report
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: rate of stringent complete response (sCR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Attitude towards diet therapy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in time spent in moderate to vigorous physical activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lapor Pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Labor Comfort
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Mean strut coverage thickness of stent
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Differentiation of vertebral bone marrow pathological lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Parent Comprehension of Discharge Instructions
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Parent Adherence to Discharge Instructions
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Number of CMC with any type of post-discharge morbidity
Endpoint domain: Adverse events/effects
Primary endpoint: Postoperative visual analogue scale (VAS) scores
Endpoint domain: Life impact
Endpoint subdomain: Pain
Primary endpoint: Total morphine consumption during hospitalization
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Gut Microbiome Genomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Oral mucositis ulcers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: First intubation success rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Accuracy of MRI in breast cancer subtyping
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Appearance of Botryomycoma
Endpoint domain: Adverse events/effects
Primary endpoint: Recurrence of Botryomycoma
Endpoint domain: Adverse events/effects
Primary endpoint: Perceived Cognitive Function
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Other signs of toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: Esthetic Improvement of white spot lesion
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Tooth remineralization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Early Bathing Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Newborn Body Temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: The duration of umbilical cord fall
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Geometric mean concentration (GMC) of serum anti-PT, FHA, PRN, FIM 2&3, DT, TT antibodies
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Proportion of serum anti-DT and TT antibodies ≥ 0.1IU/ml
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Safety and tolerability of [203Pb]Pb-PSV359
Endpoint domain: Adverse events/effects
Primary endpoint: Safety and tolerability of [212Pb]Pb-PSV359
Endpoint domain: Adverse events/effects
Primary endpoint: Antitumor efficacy of [212Pb]Pb-PSV359
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Assessment of resistive index for early predictions of acute parenchymal rejection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Early detection of vascular complications
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Proportion of Asymptomatic Patients
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Manifest Refraction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual Symptoms/Complaints
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Management of chronic pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Relapse rate at 2 years
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Changes in attentional functioning
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Changes in executive functioning
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Types, frequency and severity of adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Prosthetic complication rate
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of eligible patients that consent
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Percentage of patients randomized to the restrictive 7 gm/dL threshold that tolerate this transfusion trigger
Endpoint domain: Adverse events/effects
Primary endpoint: Indication for early termination based on interim analyses of safety
Endpoint domain: Adverse events/effects
Primary endpoint: Liver fat estimation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Radiographic alignment of the knee
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Forgotten joint score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: QoR - 15
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Cardiac apex beat (HRV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: NIPS scale score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: NIAPAS scale score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: ∆SOFA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of participants with Complete Closure of the target ulcer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Miscarriage management outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Frequency of isthmocele
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Predicting Clinical Outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Oral cavity assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 3 year Disease-Free Survival (DFS)
Endpoint domain: Mortality/survival
Primary endpoint: 24-hour Systolic Blood Pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Annual device-related serious adverse event (SADE) rate
Endpoint domain: Adverse events/effects
Primary endpoint: Blinded evaluation period (BEP) responder rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Health-Related Quality-of-Life Indicators
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life