TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Self-efficacy of geriatric oral hygiene scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Behavioral intention of geriatric oral hygiene scale
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Genetic diversity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Variant frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Periimplant marginal bone loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Vancouver Scar Scale (VSS) scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Manuel ability classification system (MACS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline ABILHAND-Kids at 8 weeks
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Infrared Thermal Camera (IRT) Calculated Human Body Temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Average Oral Thermometer Body Temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Forehead Thermometer Body Temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Average Ear Thermometer Body Temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improved sleep EEG
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Ankle instability assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in FVC%
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Decision Making Quality
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Detection of unsuspected distant metastases
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Protective humoral response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Degree of commissural alignment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Successful coronary re-access
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Presence of leaflet thrombosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change from the Baseline in the Oral Health-Related Quality of Life (OHRQoL)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Number of participants who experience dose limiting toxicities (DLTs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants who experience one or more treatment-emergent adverse events (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants who experience one or more treatment-related adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Time to union/rate of non-union
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Rates of malunion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Flynn Score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Incidence of adverse events (AEs), serious adverse events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Healthy Life Style Behaviors Scale II
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Sun Protection Behavior Scale
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Platelet aggregation of PRP samples in the presence of PAF
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Screening of plasma levels of cholesterol (PL, LDL, HDL, VLDL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Screening plasma levels of inflammatory markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Screening plasma levels of triglycerides
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Time to re-epithelialization of neurotrophic ulcer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: COPD screening questionnaire from Terrassa (EGARPOC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: COPD assessment in primary care to identify undiagnosed respiratory disease and exacerbation risk questionnaire (CAPTURE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Post Operative Opioid Use
Endpoint domain: Adverse events/effects
Primary endpoint: Numeric pain scale (NRS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Western Ontario and McMaster OA Index (WOMAC)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Maximum tolerated dose (MTD) and/or Recommended phase 2 dose (RP2D)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain/discomfort perception
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Perceived Maternity Self-Efficacy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Individual index of loss aversion
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Subjective report of decreased anxiety
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: changes in POP-Q score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient Preference for Pacemaker Device Features
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in French bleeding score (FBS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic accuracy of pre-embolization Computed Tomography Angiography (CTA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Daytime systolic blood pressure variability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Post treatment pathological staging
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: psychophysical health related events
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of Adverse Events (AEs) and Severe AEs
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Serious Adverse Events (SAEs) and Fatal SAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Substance Use Problem Recognition
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Taking Steps to Change Substance Use
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Substance-related Problems
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Composite success rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mandibular Function Impairment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Two-fold decrease in gene expression of ACE2, TMPRSS2, BSG, PPIA, PPIB, DPP4, IFNA1, IFNB1, IFNG, IFNL1, IFNL2 and ISG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Postpartum comfort scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Amount of Breast Milk the Baby Receives
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Blood Oxygen Level Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximal Oxygen Uptake - VO2max
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to cessation during cardiopulmonary testing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Glucagon Level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: ROS Level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Observed Plasma Concentration (Cmax) of IXP
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Concentration Versus Time Curve From the Time of Dosing Extrapolated to Infinity (AUC0-inf) of IXP
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Word form recall accuracy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Accuracy of generalizing novel verb to a new syntactic frame
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative urine volume output
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Complete resolved rate of foveoschisis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: onset of sarcopenia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Presence Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Anti-PRP IgG Geometric Mean Concentration (GMC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Symptomatic change of fibromyalgia
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in vascular density of the retinal capillary plexuses
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Semen concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Spermatozoa motility and morphology
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Eating Pathology Symptom Inventory (EPSI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Eating Disorder Examination Questionnaire (EDE-Q)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Muscularity Oriented Eating Test (MOET)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Muscle Dysmorphic Disorder Inventory (MDDI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Eating Pathology Symptom Inventory-Clinician Rated Version (EPSI-CRV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: degree of tooth sensitivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in CDVA at 3 months follow-up
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of unexpected Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Genotyping of FNDC5 rs3480
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Measure of IL-35 in serum
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cure rate of empyema
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement rate of empyema
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequency of SARS-CoV-2 infection
Endpoint domain: Adverse events/effects
Primary endpoint: L4-5 Supraspinous Ligament Pain pressure threshold
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Estimation of tube size
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain Scale Rating
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Basement Membrane Thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in smooth muscle cell mass
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: analgesic effectiveness on midline sternotomy pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Centre of pressure during single leg stance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in ambulatory systolic and diastolic blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Prevalence of vaccination uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Subjective Usability
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Memory change tested on Ray Auditory Verbal Learning Task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Memory change tested on Benson Complex Figure Draw and Memory
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Number of participants with immediate adverse events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with solicited injection site reactions or systemic reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Change in the frequency of heavy drinking
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Child's target vegetable preference
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Child's target vegetable liking
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Child's willingness to taste target vegetable
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Child target vegetable ad libitum consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Relative Bioavailability of LY03010 compared to INVEGA SUSTENNA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in caregiver burden score
Endpoint domain: Resource use
Endpoint subdomain: Societal/carer burden
Primary endpoint: Change in anxiety on STAI score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Total anaesthesia-related time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Detection of Pulmonary Hypertension (PH)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Stratification of PH severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Time from randomization to discharge
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Change from baseline neuropsychological study at early period (one month)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline neuropsychological study at late period (one year)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from early period (one month) neuropsychological study at late period (one year)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-UVA pigmentation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Lung-tissue immune-checkpoint profile in acute rejection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Lung-tissue immune-checkpoint profile in chronic rejection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Epicardial fat volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: time spent on LIMS
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Chimeric antigen receptor (CAR) T-cell product efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diabetes Distress Score-T1
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Perception of family-centered care level
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: CD30 distribution visualisation by PET-scan
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety profile of the 89Zr-brentuximab tracer
Endpoint domain: Adverse events/effects
Primary endpoint: Relation of 89Zr-brentuximab biodistribution and CD30 expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Difference in cortisol levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Phlebitis Assessment Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Birth Experience Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Percentage of participants with at least one safety event
Endpoint domain: Adverse events/effects
Primary endpoint: Subjective Drug Intensity Ratings
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Child's level of physical activity
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Duration of screen time (TV/computer)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Status of organized planned physical activity
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Cormack-Lehane classification
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: CRESS response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post Operative pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean time spent in positions of high ergonomic risk
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma Antimicrobial Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bronchoalveolar Antimicrobial Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Antimicrobial lung tissue penetration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: RCB 0-1 points ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean difference of 24-h natriuresis and daily sodium elimination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Composite response rate of GL severity at maximal frown
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in perceived selfcare
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Registered sickness absence
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: IBS Symptom Severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of VAS pain scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of micturitions per 24h
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Reported confidence with LTBI management
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Rates of recruitment and retention
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Ratings of satisfaction
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: changes in cerebral perfusion after surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: neurological status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 25(OH)D maternal serum level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: 1,25(OH)2D maternal serum level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: VDBP maternal serum level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: 24,25(OH)2D maternal serum level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Numbers of participants with hyperbilirubinemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Accuracy of the model predicting cerebral palsy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Acute and chronic long COVID symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Pain Assessment - Oxford Hip Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in mobility, self-care, usual activities, pain/discomfort and anxiety/depression - EuroQol
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change in physical, mental, and social health - PROMIS Global-10
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in fecal hemoglobin content
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Binocular photopic Distance Corrected Intermediate Visual Acuity (DCIVA) at 66 cm
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Symptom Distress scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: PAC-SYM Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: MRI-derived free water (FW) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peripheral blood mononuclear cell (PBMC) nuclear receptor-related 1 protein (Nurr1) mRNA expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum neurofilament light chain (NfL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes