TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Survival without severe neurological sequelae (CPC 1-2) at 3 months
Endpoint domain: Mortality/survival
Primary endpoint: Maximum Observed Plasma Concentration (Cmax) of PF-07321332
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Area Under the Plasma Concentration-time Profile From Time Zero (0) to Extrapolated Infinite Time (AUCinf) of PF-07321332
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Renal Clearance (CLr) of PF-07321332
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: BSID-III cognitive z-score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BSID-III language z-score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BSID-III motor z-score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BSID-III social-emotional z-score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: BSID-III adaptive behavior z-score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Freedom from Atrial Fibrillation/Atrial Flutter (AT/AF) Recurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in NT-proBNP Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Proportion of weight increase relative to baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Safety and tolerability of Thymus Nuclear Extract
Endpoint domain: Adverse events/effects
Primary endpoint: 5D-ASC total OAV score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Engagement with recruitment message
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Proportion of participants with complete wound closure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Late lumen loss at 9 months after index PCI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in plasma concentration of amikacin during the first 24 hours after administration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in plasma concentration of piperacillin during the first 24 hours after administration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in plasma concentration of tazobactam during the first 24 hours after administration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: life quality score (SPF 36)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: life quality score (EQ-5D-5L)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: End-of-Life Care Preferences Documentation
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Performance of the autonomic nervous system
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Print concept knowledge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Alphabet knowledge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Name Writing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Spelling
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: score of Picture Arrangement subtest at WISC-III
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: score of a Motor Planning test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Vestibular Rehabilitation Benefit Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Safety of CAR-NK cell therapy
Endpoint domain: Adverse events/effects
Primary endpoint: Efficiency of CAR-NK cell therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Abstain from health-risk behaviour
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Violent acts
Endpoint domain: Adverse events/effects
Primary endpoint: Excitement Factor of the Positive and Negative Syndrome Scale (PANSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Severe postoperative morbidity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility of monitoring fetal signals
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Safety of the prototype device
Endpoint domain: Adverse events/effects
Primary endpoint: Neurobehavioral Symptoms Inventory
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Incidence of intestinal barrier injury
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Observed ADL motor ability
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Selfreported ADL ability
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Shoulder Pain And Disability Index
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Quick Disability of the Hand, Arm and Shoulder
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Evaluation of joint range of motion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post Traumatic Stress Disorder (PTSD) Change in Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in sarcopenia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Performance on computerized tasks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Resting state and event-related electrophysiology
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in blood kynurenic acid (KYNA) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Maximum observed plasma concentration (Cmax) of ABBV-903
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of septic cardiomyopathy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: change in patients weekly step count
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: change in fatigue level
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: incidence of residual neuromuscular block
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Shoulder pain and disability index (SPADI) Score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: change-from-baseline in QTc interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Headache Disability Index
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: successful extraction of teeth
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: MOAA/s scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: no need for rescue medications
Endpoint domain: Adverse events/effects
Primary endpoint: Time of PFO tunnel passage
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Amount of Opioid Medication Required for Pain Relief
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of adverse events (AEs) and serious adverse events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of adverse events leading to discontinuation (DAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Area under the plasma concentration curve from zero to the last quantifiable concentration (AUClast)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Child age and sex-adjusted Body Mass Index (BMI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Effectiveness of Transformainal Epidural Injection
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quantification of anti PD-1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: CLUE Comfort Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: PTSD Checklist (PCL-5)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: hand grip
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to confirmed progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak Force (forefoot)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Force Impulse (forefoot)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak Force (hindfoot)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Force Impulse (hindfoot)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Numerical Pain Rating Scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Modified Socket Comfort Score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Detection of subclinical phrenic nerve injury
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Changes in diaphragm kinetics
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Birth control satisfaction
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Health-related work productivity
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Object Response Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportional Change From Baseline in Serum Concentration of NT-proBNP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Kidney survival post transplant
Endpoint domain: Mortality/survival
Primary endpoint: Push up test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Seated medicine ball throw test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Unilateral single arm shot put test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postural Assessment Scale for Stroke Patients (PASS-T)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Retained
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Children's symptoms as reported by parents
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Food literacy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Occurrence of thromboembolic event(s)
Endpoint domain: Adverse events/effects
Primary endpoint: Reduction of postoperative low-cardiac output syndrome (LCOS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of early drug discontinuation
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Incidence of LVEF < 40%
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Late Onset Sepsis (LOS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Weight measurement of preterm baby
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: complication rate of surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Bone geometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility of the BABE program (sample size)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Feasibility of the BABE program (retention)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Feasibility of the BABE program (randomization)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Mean attack frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Il-6 concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Il-18 concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Il-4 concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Intubation-free survival rate
Endpoint domain: Mortality/survival
Primary endpoint: Change in demoralization Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in k parameter of the delay discounting task (DDT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in total number of premature responses in the 4-choice serial reaction time task (4-CSRTT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Specificity and Sensitivity of screening markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lactate synthesis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Working Memory (WM) improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Percentage of atrial fibrosis in the left atrium
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in energy expenditure (kcals/day)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in respiratory exchange ratio (au)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: change in alveolar ridge width
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Risk of re-offending
Endpoint domain: Adverse events/effects
Primary endpoint: Failed nutritional recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Number of Grade >= 2 Cytokine Release Syndrome (CRS) Events
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Adverse Events (AEs) of Special Interest (CRS and ICANS)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants with Treatment-emergent adverse events (TEAEs), Serious Adverse Events (SAEs), and Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: PTE resolution rate 1 month after thrombectomy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline in heart rate during stressful lethal force decision making task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change from baseline in respiration rate during stressful lethal force decision making task
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline in heart rate variability during stressful lethal force decision making task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change over time in alpha amylase during stressful lethal force decision making task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change over time in cortisol during stressful lethal force decision making task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Reduced PHQ-9 Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduced GAD-7 Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increased Quality of Life Score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Desensitising effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Side-effect frequency and severity
Endpoint domain: Adverse events/effects
Primary endpoint: Time to peak change in numerical rating scale (NRS, 0-10)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 24 hour urine volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: 24 hour urine creatinine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: PHQ-A results
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: IPT-AG Fidelity
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Cerebrovascular reactivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Correlation between venous whole blood potassium and capillary potassium
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Percent of Participants Screened Eligible
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Percent of Participants Enrolled
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Percent of Participants Retained
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Foot and ankle ability measure (FAAM)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Cumberland Ankle Instability Tool (CAIT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in pain scores as measured by USSQ Pain Survey
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in pain scores as measured by PROMIS questionnaire
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in pain scores as measured by Likert Scale Questionnaire
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in serum angiotensinogen from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change in endothelial cell percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUCtau of Bulevirtide (BLV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax,ss of Bulevirtide (BLV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Extracutaneous manifestations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of vaginal bleeding
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Safety of TCD601
Endpoint domain: Adverse events/effects
Primary endpoint: Acceptability of Study Procedures
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: prevalence of MG infection
Endpoint domain: Adverse events/effects
Primary endpoint: prevalence of MG resistance mutations
Endpoint domain: Adverse events/effects
Primary endpoint: Progression through the ACLS clinical simulation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum tolerated dose (MTD) of [225Ac]-FPI-2059
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Radiation dose of [111In]-FPI-2058 and [225Ac]-FPI-2059
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Complete obliteration of varices
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Changes in resting-state connectivity (FC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in dopamine (DA) availability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in fMRI activation on an apathy related task
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serious Adverse Events (SAEs) related to the BPF implant
Endpoint domain: Adverse events/effects
Primary endpoint: Bronchopleural Fistula (BPF) closure at 3 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total energy (kcal) ordered
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Rate of clinically relevant postoperative pancreatic fistula (POPF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Complete Response Rate (CR rate)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite complete remission rate (CRc)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of DLT AEs
Endpoint domain: Adverse events/effects
Primary endpoint: MTD and RP2D of TARA-002
Endpoint domain: Adverse events/effects
Primary endpoint: Knee Injury and Osteoarthritis Outcome Score (KOOS) PAIN
Endpoint domain: Life impact
Endpoint subdomain: Pain
Primary endpoint: Incidence of significant decrease in ventilation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Percent of patients achieving PSA < 0.05 ng/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the plasma concentration-time curve from time 0 to time t (AUC(0-t))
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the plasma concentration-time curve from time 0 to infinity (AUC(0-∞))
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in MRI biomarkers of endothelial dysfunction: aortic arch
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes