TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Prevalence of acute stress disorder
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MACE risk reduction
Endpoint domain: Mortality/survival
Primary endpoint: number of treatment escalations needed to maintain intraocular pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: number of visits needed throughout the follow-up period
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: need for trabeculectomy
Endpoint domain: Adverse events/effects
Primary endpoint: preserved lung function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Pain/discomfort
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Mean chest compression depth (CCD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean chest compression rate (CCR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain catastrophing
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: 24-h urine protein
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: acute care use
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Mean change in SUA from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Breastfeeding rate of mothers returning to work after giving birth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Seattle Angina Questionnaire (SAQ)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Risk of ASD associated with ADHD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Angiographic vasospasm occurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: New vasospasm-related neurological symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Delayed ischemic neurological deficits/strokes
Endpoint domain: Adverse events/effects
Primary endpoint: OEP adherence
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Psychosocial factors improvement
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Mean change in ETDRS BCVA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Risk of Heart Failure (HF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Risk of Type 2 Diabetes (T2D)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: long-term outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient preparedness for surgery
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Pain intensity (visual analog scale score)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quality of pain (McGill pain questionnaire score)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sustained recovery rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Influenza vaccine knowledge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tdap vaccine knowledge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intention to receive vaccines
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improvement of dizziness symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement of negative mood
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Time to TB
Endpoint domain: Mortality/survival
Primary endpoint: Pigmentation scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Water content of the stratum corneum
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: LCQ-T total score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Circulating 25(OH)D2 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Total serum levels of 25(OH)D
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Circulating vitamin D (vitamin D2 + vitamin D3)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Confidence in accessing SRH services
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Belief in consistent birth control use
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Control over birth control use
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Extubation bucking frequency
Endpoint domain: Adverse events/effects
Primary endpoint: Post-extubation sore throat rate
Endpoint domain: Adverse events/effects
Primary endpoint: excellent cosmetic and functional results
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: 24-month primary patency rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Suturing duration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Number of suture packs used
Endpoint domain: Adverse events/effects
Primary endpoint: Subjective difficulty of suturing
Endpoint domain: Adverse events/effects
Primary endpoint: Reduction of antibiotic prescriptions for upper respiratory infections (URI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction of antibiotic prescriptions for bronchitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum oxygen consumption (VO2max)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Heart Rate (HR) at the end of initial workload
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Workload necessary to maintain exercising HR
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: atrial-arrhythmia-free survival
Endpoint domain: Mortality/survival
Primary endpoint: Incidence of AKI (Acute Kidney Injury)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: weekly attack rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: severity-weighted attack rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cognitive CMD risk perception
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Lower dose of epidural analgesia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Shorter opioid requirement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quitting-related attitudes and intentions
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Perioperative opioid consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Barthel Index of activities of daily living scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: National Institutes of Health Stroke Scale scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Gain of ETDRS letters from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: office visit-to-visit ARV of SBP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: evening day-to-day BPV indexes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Postoperative adverse effects
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of urine occult blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Urinary outcomes
Primary endpoint: Frequency of gout attacks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: intake of total grains
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: intake of protein
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: ΔE00 values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Unplanned reoperation for hematoma
Endpoint domain: Adverse events/effects
Primary endpoint: nighttime sleep complaints
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: ADHD severity
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Endoscopically diagnosed oesophageal lesions (EDEL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative AF recurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reading level of PEMs
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Complexity of side effects description
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Total score of humanistic medical skills assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: satisfaction with initial wound healing and appearance
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Polyp recurrence rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Major Molecular Response (MMR) at 18 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intraoperative hemodynamic changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: flexion–rotation test to the more restricted side at T1
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: flexion–rotation test to the more restricted side at T2
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: flexion–rotation test to the less restricted side at T1
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: post-treatment anxiety scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of hazards identified
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: HIV-infected infants alive, in care, and virally suppressed at 12 months
Endpoint domain: Mortality/survival
Primary endpoint: Sympathovagal balance (LF:HF ratio)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Motor symptoms reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-operative anaemia incidence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Krimmer-Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Need for central venous access
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Microbial diversity (alpha and beta diversity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinical Disability Index (CDI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sustained Disability Index (SDI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-care adherence scores
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: daily stool number change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: normalized C-reactive protein levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: clot lysis time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Viral load suppression at follow-up
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-reported adherence at follow-up
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Choice of fruit
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Desire for unhealthy products
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Intention to consume unhealthy products
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Softer stooling pattern
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Difficulties in passing stool
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Change in RBC from perioperative to postoperative period
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Deformation Amplitude Ratio (DA ratio)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Inverse Radius (InvRadMax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: A2 Time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SPI values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improved recruitment
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Flexibility of trial delivery
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Reduction in neonatal mortality
Endpoint domain: Mortality/survival
Primary endpoint: Proportion of patients who never reached baseline seizure frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Median time-to-nth seizure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Longest duration of convulsive seizure-free days
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Depression score reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Newborns with danger signs immediately after birth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: modified Rankin Scale (mRS) scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Use of home dialysis at 180 days
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change of scar width
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient satisfaction with treatment results
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Gingival health
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Craniovertebral angles improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Head tilt improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Strength and endurance of DCF muscles improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PAT1 expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 5,000 m running performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Participants' perceptions of clinical feedback
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: TGP-IgA1 levels in nasal fluid
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: TGP-IgA2 levels in nasal fluid
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum TGP-IgG4 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: percentage weight gain above target
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: change in weight per week
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: overall failures
Endpoint domain: Mortality/survival
Primary endpoint: surgical failures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: composite adverse outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AF/AT recurrence rates
Endpoint domain: Mortality/survival
Primary endpoint: Kaplan‐Meier AF/AT‐free survival curve rates
Endpoint domain: Mortality/survival
Primary endpoint: Reduction in serum ECM‐neoepitope biomarkers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of postoperative adverse reactions
Endpoint domain: Adverse events/effects
Primary endpoint: VAS scores at 7 days post-operation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Excellent and good rate of recovery
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: mean knowledge test scores
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Serum concentrations of TG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Serum concentrations of total saturated FA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Serum concentrations of ω‐3 PUFA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: depressive symptom response trajectory
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: acne lesion count reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: hydration (stratum corneum hydration)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: residual swelling on the 30th post-OP day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: monthly average days with neurological symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Migraine-Specific Quality of Life scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: completion and reaction times of working memory and attention activities
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Dairy fat intake reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BC 007 area under the concentration-time curve (AUC0-24)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Drug-related adverse events (increase in bleeding time)
Endpoint domain: Adverse events/effects
Primary endpoint: fGPCR-AAb neutralisation efficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite reach distance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Help-seeking intentions for leukocoria
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Help-seeking intentions for strabismus
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: hCG positive pregnancy rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: FIX-IT score improvement
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Rate of superficial infection
Endpoint domain: Adverse events/effects
Primary endpoint: normalized asthma exacerbations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Comprehensive QoL
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: High‐sensitivity C‐reactive protein (hs‐CRP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Tumor necrosis factor (TNFα)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: improved physical self-efficacy
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: ability to perform physical activity
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Discriminability index
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Days Alive and Hospitalized (DAH365)
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Mortality days
Endpoint domain: Mortality/survival
Primary endpoint: Major thromboembolism and death
Endpoint domain: Mortality/survival
Primary endpoint: Functionality improvements
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Clinical improvement within 28 days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Recovery time of spontaneous breathing and extubation time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BCS score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change in Peri-implant Bone Level (PBL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: freedom from congestion at 72h
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: degree of dyspnoea assessed using the Borg scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Graft rupture rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Contralateral ACL injury rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Willingness to discuss advance care planning before illness
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: serum IL-6 level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes