TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Obstetrical complications
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Fear of child birth
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Diversity of gastrointestinal microbiota
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Circulating Interleukin 6
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Score of Image quality
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of common mental health conditions
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Incidence of common mental health conditions
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Mental health management patterns
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: 'Sick days' and unemployment burden
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Psychological complications
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Safety and tolerability of SP-8356
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With Severe Adverse Event (SAE)
Endpoint domain: Adverse events/effects
Primary endpoint: Area Under the Plasma Concentration Time Curve (AUC) of Brensocatib
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Observed Plasma Concentration (Cmax) of Brensocatib
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to Reach Maximum Observed Plasma Concentration (Tmax) of Brensocatib
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants who Experienced at Least one Adverse Event (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: Parent Self-Rating of Depression
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Parent Self-Rating of Anxiety
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Z score of weight gain at 36 weeks corrected gestational age
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain self-assessment
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: X-ray changes of osteoarthritis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Emotional awareness of rural children
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Emotion regulation self-efficacy of rural children
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from Baseline Growth Hormone Post exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change from Baseline Insulin-like Growth Factor-1 Post exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Percentage of Participants with Measurable Residual Disease (MRD) Positivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Percentage of Participants with Complete Remission (CR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: All Cause Non-elective Acute Care Post Discharge Utilization
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Demand rate of endotracheal intubation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Levels of circulating anti-nephrin autoantibodies
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: changes in single pulse TMS: mapping
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: changes in single pulse TMS: resting motor threshold
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Time to Clinical improvement (TTCI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intensity of grief
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Improvement in most significant symptom
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Microbiological diagnosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Syndromic diagnosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stiffness of prosthetic feet
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Index of anthropomorphicity IAm
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Index of anthropomorphicity IAb
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MDS-UPDRS III
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to overt myeloid malignancy
Endpoint domain: Mortality/survival
Primary endpoint: Imaging results
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: best objective response during treatment period
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants who experience at least 1 Dose Limiting Toxicity (DLT)
Endpoint domain: Adverse events/effects
Primary endpoint: Objective response rate (ORR) defined as the percentage of participants with partial response or complete response based on RECIST 1.1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Change in ECOG performance status
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Mean change in cochlear implant internal microphone frequency gain response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Grade ≥3 immune-mediated Adverse event
Endpoint domain: Adverse events/effects
Primary endpoint: Reduction in toxicant exposure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adjusted mean change in global health status/QoL score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Average Numeric Rating Scale (NRS)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Weighted Frequency of Intentional Communication
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Vineland-3
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Parenting Efficacy Scale (PES)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Efficacy of ConvaFoam dressings in exudate management
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: De Jong Gierveld Loneliness Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: UCLA Loneliness Scale (Neto)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Patient-reported outcome completion
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Objective Response Rate (ORR-PIT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Test-specific performance outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Noninducibility at the end of procedure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Arrhythmia free survival
Endpoint domain: Mortality/survival
Primary endpoint: Plasma levels of Calcitonin Gene-Related Peptide
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of Participants With HIV Viral Load ≥832 Copies/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Posture and Postural Ability Scale (PPAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bunnell's Scoliometer
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MD Anderson Symptom Inventory for Head and Neck Cancer (MDASI-HN)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: CGM accuracy - mean absolute relative difference (MARD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Willingness to Participate in Clinical Trial
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Antibiotic concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in daytime mean systolic blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in the composite index of antihypertensive drugs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lab Toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Patient-reported genitourinary (GU) symptoms
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Patient-reported gastrointestinal (GI) symptoms
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Grading scores comparison
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: morphometric measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Diagnostic test accuracy - primary reference standard
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic test accuracy - composite reference standard
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Usability of the SanaCoach
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Pseudo-AKI incidence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: New dementia diagnosis
Endpoint domain: Mortality/survival
Primary endpoint: Self-assessed hand function
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Boston Carpal Tunnel Questionnaire (BCTQ) changes
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Global symptoms score (GSS) changes
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Normoxia time SpO2 > 92%
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total volume of new cerebral ischemic lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Quarterly rate of use of AEDs
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Mean dose of AEDs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Contractile properties of Quadriceps muscle
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Anteromedial lunge Functional Performance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Step-down Functional Performance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Balance and reach Functional Performance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: participation rate in both groups
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: response rate at 12 weeks follow-up
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Proportion of patients achieving a response according to preliminary STAR at week 24
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean Change in HbA1C
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: MRS score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Incidence of residual ventral curvature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of meatal stenosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of urethral stricture
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of glans dehiscence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of urethro-cutaneous fistula
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of urethral diverticula formation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of changes in exudate volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: TEAEs (Treatment Emergent Adverse Events)
Endpoint domain: Adverse events/effects
Primary endpoint: TRAEs (Treatment Related Adverse Events)
Endpoint domain: Adverse events/effects
Primary endpoint: SIAEs (Serious Adverse Events)
Endpoint domain: Adverse events/effects
Primary endpoint: SAEs (Serious Adverse Events)
Endpoint domain: Adverse events/effects
Primary endpoint: Change in blood amino acid concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in gut microbiota type
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in gut microbiota population size
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction of interventions number on rectum
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Transcutaneous bilirubin level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fear-avoidance Belief Questionnaire (FABQ)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Number and maturity of oocytes retrieved
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Prevalence of faecal phage carriage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total Dose of IV Morphine in the first 24 hours post op
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of patients responding to nutritional education program
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Percentage of treatment time with mean arterial pressure within 80-90 mmHg
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: remission of the treated fistula
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tissue distribution of 124I-AT-03
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hunger/Satiety
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: numerical analog score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: DEXA (GE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hearing-in-Noise Test Performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Triple Digit in Noise Test Performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Size of auditory neural response in background noise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Timing of auditory neural response in background noise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in 4-Domain NPC Severity Score (US only)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in 5-Domain NPC Severity Score (ex-US)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline urinary organic acids levels after 6-month intervention
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline thyroid disease-related quality of life at 6-months
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change from baseline psoriasis-related quality of life at 6-months
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Rate of Benzodiazepine prescriptions
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Likert pain scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Range of Motion by Goniometer
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: thalamocortical functional connectivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: alpha oscillations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in levels of Short Chain Fatty Acids (SCFA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in levels of branched chain fatty acids (isobutyrate and isovalerate)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in post-operative pain intensity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SLN unilateral detection rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prothrombin time reference interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Activated partial thromboplastin time reference interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Fibrinogen reference interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Hemoglobin reference interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Red blood cell count reference interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: White blood cell count reference interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Activation of the habenula during Pavlovian conditioning
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Habenula response to unexpected loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Preference for high-reward probability
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: TPQue assessment
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: NEI-VFQ-25 assessment
Endpoint domain: Life impact
Endpoint subdomain: Visual functioning
Primary endpoint: Mean Peritoneal Fluid Glucose ratio (D4/D0)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Mean Ultrafiltration Volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean 4 Hour Peritoneal Fluid to Plasma Creatinine (D/P)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Peritoneal Fluid Sodium Dip
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Steatosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver and biliary outcomes
Primary endpoint: Fibrosis Marker FIB-4
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Behavioral Approach Task (BAT) scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Strongness of LiquiBandFIX8®
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Adherence to TRE
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Occurrence of hypoxia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Pain assessed by NRS at rest and movement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Perception threshold for the excitability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-perceived workload
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Parent Subjective Connection to Fetus/Infant
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Prenatal care utilization
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Substance use treatment utilization
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Antihypertensive and/or statin medications dispensed
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in wart number
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change in mean size of genital condyloma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Achievement of Success on the Investigator Global Assessment (IGA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Presence or absence of cardiac murmurs
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Global disability progression
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Limb Volume Maintenance or Improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: progression-free survival rate at 3 months
Endpoint domain: Mortality/survival
Primary endpoint: Overall Changes of Cycloplegic Objective Refraction (spherical equivalent refraction, SER)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes