TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Premenstrual syndrome scale (PMSS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Incidence of Bladder cancer
Endpoint domain: Mortality/survival
Primary endpoint: Insulin sensitivity and β-cell function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Muscle relative refractory period (MRRP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Early supernormality (ESN)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Sputum Bacterial Culture
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: bleeding pattern preferences
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improvement in pulmonary congestion score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Improvement in heart failure symptoms score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Actual adverse events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Actual preventable adverse events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Patients Who Are Opiate-free
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Patients Who Are Opiate-free at 10-14 Days Postoperatively
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Parents' Postoperative Pain Measure (PPPM) Scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in severity of eating disorder symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in severity of depressive symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in body image self-esteem
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Area under the plasma concentration-time curve from time zero to time of the last quantifiable concentration (AUC[0-T])
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time-intensity curves
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: incident chronic renal failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: incident pulmonary disease
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: incident cardiac failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: incident pulmonary hypertension
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: diagnosed with Post COVID
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: incident psychiatric disease
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Determine the Recommended Phase 2 Dose (RP2D)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Safety of the CT Lucia 601 IOL
Endpoint domain: Adverse events/effects
Primary endpoint: Detection of retinopathy of prematurity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ophthalmic outcomes
Primary endpoint: Bristol Stool Scale (BGS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Disease severity in children with pneumonia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Subjects Experiencing Treatment-Emergent Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Changes in parameters of intestinal barrier function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Incidence and Severity of Dose-limiting Toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Evaluation of muscle strength from an isokinetic device
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Evaluation of the preferential speed of walking in an ecological situation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Evaluation of the energy cost of walking
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Difference in proportion of elevated plasma lipoprotein(a)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Heart Failure Hospitalizations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: KCCQ Improvement
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: R2* Index within the homolateral black substance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: O₂ Saturation (mmHg) (SpO₂)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Severity of pushing behavior
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: self-efficacy scale scores of adherence to drug therapy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of new patients with Cerebral Arteriovenous malformation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Motor control disorder
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Core muscles endurance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of children who complete vision evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Clinical Global Impression scale - Severity (CGI-S) score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Child and Adolescent Trauma Screening (CATS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: WHO-5 Well-being Index
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Subjective symptom improvement
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Desires for Drug
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: % of bleedings reaching hemostasis within 3 minutes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Primary molar relationship
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Perceived Stress Scale (PSS-14)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Testicular self-examination behavior
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in symptom severity (patient report)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Patients' Health-related quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Difference and change in percentage of readmissions
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Bladder Compliance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Bladder Sensation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change in skin mitochondrial health and biological age
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change in skin barrier function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Vergence facility
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total standard drinks
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in ctDNA Level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hearing in Noise Test (CHINT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reading span test (CRST)
Endpoint domain: Cognitive functioning
Primary endpoint: Blood neurological biomarkers levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Cognitive disorders assessment (global assessment)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Memory disorder assessment
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Anxiety self-assessment
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Pain self-assessment
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Geometric mean titer of antibodies
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Cross-reactivity against different VAR2CSA variants
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Percentage of binding inhibitory activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum TMAO levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Echocardiographic dyssynchrony index (Global Left Ventricular Myocardial Work Efficiency)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Biomarkers related to cancer metastasis and drug resistance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Economic Burden
Endpoint domain: Resource use
Endpoint subdomain: Societal/carer burden
Primary endpoint: Disease Burden
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Diagnostic accuracy of AI algorithm
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Post-anesthesia care unit (PACU) pain score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pulpal floor temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Restoration temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Biochemically confirmed point-prevalence abstinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mortality at three months after hospital discharge
Endpoint domain: Mortality/survival
Primary endpoint: Mortality at twelve months after hospital discharge
Endpoint domain: Mortality/survival
Primary endpoint: Upper Limb Functionality
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of Serum Creatinine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Number of Participants Requiring Intubation
Endpoint domain: Adverse events/effects
Primary endpoint: Hospice and Palliative Care Questionnaire (HPCQ)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Acute cell rejection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Severe adverse reactions and events rate
Endpoint domain: Adverse events/effects
Primary endpoint: Body surface area ≤1%
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Calcaneo-tibial angle measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Navicular bone drop test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Normalized Dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in HBsAg from baseline at 24 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Metabolic power
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plantar flexor strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: safety (AE or SAE)
Endpoint domain: Adverse events/effects
Primary endpoint: Change from baseline on the Classroom Performance Survey (CPS)
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Change from baseline on the School Functioning Scale (SFS)
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Change from baseline on the Children's Organizational Skills Scale--Parent Report (COSS-P)
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Assessment of redox status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Evaluation of glycation status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quantification of arterial target organ damage (TOD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: 12-week forced expiratory volume in 1 second (FEV1) (% predicted) change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: composite outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CGH-array abnormality
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sodium weight
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Efficacy of tele-rehabilitation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Area under the concentration curve for plasma caffeine (AUC0-t)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak caffeine concentration (Cmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to maximal plasma caffeine concentration (Tmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum prealbumin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Uremic toxins assay
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Aβ40 and Aβ42 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: P-Tau levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: NFL levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Cardiac function recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Safety of the DiaSole insole
Endpoint domain: Adverse events/effects
Primary endpoint: Rates of adoption of rTMS in Nicotine Dependence Clinic
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in Step Count via the ActiGraph wGT3X-BTLE Accelerometer
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in six-minute walk test (6MWT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in pain measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: PIC Score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: FOC based performance of students after simulation
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: FOC based performance of students after internship
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: CCTA without obstructive CAD
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Adherence to the recommended amount of study product
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Product palatability rated on a Likert scale by the patient after 28 days
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Gastrointestinal tolerance daily diary as reported by the patient
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Change in Phe levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: plasma tacrolimus concentration without adjustment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: plasma tacrolimus concentration with adjustment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stability Quotient of Implants (SQI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Horizontal bone dimensions (HBDs)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peri-implant Bone Density (PBD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean change of height
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean change of Height for Age - Z score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Soft Tissue Stability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SPECT/CT-based 99mTc-DARPinG3 uptake value in primary tumor
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SPECT-based tumor-to-background ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Evaluation of endocrine system disruptions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Detection rate of ctDNA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of ctDNA in blood samples
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Healing rates of large periapical lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of patients with category 0-1
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Immune cell comparison in blood and colonic biopsies
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Geometric Mean Titers (GMTs) of HI antibody
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Intraprocedural Major Device-Related Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Microbiome diversity index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Transepidermal Waterloss (g/h/m2)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Muscle stiffness (change)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Average change in MADRS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility of weaning strategies
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Plasma Concentration During the Dosing Interval at Steady State (CmaxSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Plasma Concentration Versus Time Curve for One Dosing Interval at Steady State (AUC(0-t)ss)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Intervention-Related Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Measurement of Biomarker Response to an Intervention in the Blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Level of CRP (C-reactive protein)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Pro-inflammatory cytokines level (IL-1, IL-6, TNF-α)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Symptom Severity Measurement
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Mental Health Status
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in mental health recovery
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Postural balance: Mean velocity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Functional assessment: Walking speed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Functional assessment: Duration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Numeric Pain Rate Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hand Held Dynamometer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Study Completion Rate
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Changes in burnout score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Major organ deterioration progression-free survival (PFS)
Endpoint domain: Mortality/survival
Primary endpoint: Safety of DP CD8 TIL
Endpoint domain: Adverse events/effects
Primary endpoint: Change in occurrence of recurrent caries
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Change in occurrence of marginal stains
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 12-month progression-free survival rate
Endpoint domain: Mortality/survival
Primary endpoint: Change in MDASI scores
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Incidents of dehydration
Endpoint domain: Adverse events/effects
Primary endpoint: Change from baseline Pain at 18 days
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Change from baseline Quality of Life at 18 days
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change from baseline Knee Health Status at 18 days
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning