TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Diagnostic performance of blood assay
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Change in Distance Walked During a 12 Minute Walk Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in number of remembered items
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Circulating free DNA detection
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of days under treatment with broad-spectrum antibiotics
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Area Under Receiver Operating Characteristics (AUROC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total Noradrenaline and vasopressin requirement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Daytime time-in-range (TIR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of vitamin D
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Complete response within 48 hours after surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hamilton Depression Rating Scale- 17
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Variation in the force of external rotation of the elbow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Berberine plasma and serum concentration (AUC0-48 hours)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety of sirolimus in the management of BSCMs
Endpoint domain: Adverse events/effects
Primary endpoint: Overall response rate (ORR) by the IRC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of subjects with positive immunoassay response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in WOMAC INDEX
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Range of Motion at knee joint both in extension and flexion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Static visual analogue score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tobacco and other drug use reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Dementia Knowledge
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Dementia Attitude
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Pathology progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean percentage of time that the pH of the oesophagus is greater or equal to 4
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: 2-minute Step Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Timed Arm Curl
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 30 second Chair Stand
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Feeding and Eating in AutiSm Together Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: survival of patients treated with suramin
Endpoint domain: Mortality/survival
Primary endpoint: Intraoperative anesthetic dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change on Maternal Antenatal Attachment Scale (MAAS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Overall accuracy value of sECP in CMPA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sensitivity of sECP in CMPA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Specificity of sECP in CMPA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Who Are Dependent on High Flow Oxygen Devices or Invasive Mechanical Ventilation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Compound Action Potential (CAP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in MDS-UPDRS Part III total score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in MDS-UPDRS Part IV total score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Geometric mean titres (GMTs)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Time on One Leg Standing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Standardized uptake values (SUV) of [68Ga]Ga-DFO-B
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Target-to-background ratios of [68Ga]Ga-DFO-B
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Glycated Haemoglobin (HbA1c) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Reduction in odds of respiratory event
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: symptom specific Quality Of Life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Long-term safety of REACT
Endpoint domain: Adverse events/effects
Primary endpoint: Pulse Oximeter Bias
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic property of an AI model
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Individual perception of impairments due to cognitive deficits
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: EuroQol Visual Analogue Scale Score (EQ-VAS)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Engagement composite
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Hair Loss Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Maximum Observed Concentration (Cmax) of LY3537982
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Concentration-Time Curve (AUC[0-inf]) of LY3537982
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC from Time 0 to time of the last measurable concentration (AUClast) of LY3537982
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of adherence to Positively Smoke Free - Mobile (PSF-M)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of participants who complete the low dose chest CT scan within 60 days of enrollment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants With Continuous Laryngoscopy During Exercise Tests
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Incidence of delayed neurocognitive recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in patients' UI symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Number of participants with a score of 5 or greater in VAS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Absence of CSF Leaks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Measles vaccine coverage in children aged 12-23 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Measles vaccine coverage in children 6-12 months at inclusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of Responders based on eosinophil counts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Mean absolute change in total symptom score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: AFEQT Scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Time of OGT and nasogastric tube connection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: blood pressure (BP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: pulse (P)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: respiratory rate (RR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in serum level of low-density lipoprotein cholesterol
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Platelet Aggregometry Light Transmission
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Changes in number of awakenings
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Change in duration of awakenings
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Percent positive change in 8-OHdG
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Expired CO2 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in Urine USG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change in Urine Osmolality
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change in Plasma Creatinine Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Montgomery-Åsberg Depression Rating Scale (MADRS) score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Sheehan Disability Scale (SDS) score
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Quality of Life Enjoyment and Satisfaction Questionnaire Short-Form (Q-LES-Q) score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Delineation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility for the caregiver to engage with and complete baseline assessments
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Feasibility for the caregiver to access educational materials and community resources
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Feasibility for the practice of identifying potential patients/caregivers
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Incidence of COVID-19 cases after vaccination
Endpoint domain: Mortality/survival
Primary endpoint: Incidence of CAKUT in neonates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Area under the concentration-time curve of BI 456906 in plasma (AUC0-∞)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of patients treated who experience treatment-emergent adverse event
Endpoint domain: Adverse events/effects
Primary endpoint: Number of ticks found on clothing
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Number of tick bites
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Changes in self-evaluation questionnaires
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Changes in orbital bony volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Psychological fulfilment at work
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change from baseline in total Corneal Fluorescein Staining (NEI scale)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Change from baseline in Dryness Score (visual analogue scale [VAS] Severity of Dryness)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Changes in oxygen saturation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Number of completed ePRO responses
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Plasma dehydroepiandrosterone levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change in the acrophase of urinary 6-sulphatoxymelatonin (aMT6s) excretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in the acrophase of the rhythm of the median reaction time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Transfusion of red packed blood cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Durability of remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in Vaginal pH
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from Baseline in the deep musculature with the PERFECT protocol
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Analysis of the impact on QoL (Quality of life)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Endothelial progenitor cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Measurement of Providers' Self-Efficacy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: RUBI Implementation fidelity
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Satisfaction with RUBI intervention
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in perceived mental health
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in caregiving burden
Endpoint domain: Resource use
Endpoint subdomain: Societal/carer burden
Primary endpoint: Change in caregiving competence
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Spirometry test results
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Corticospinal excitability measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Muscle function measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Lumbar stability measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Landmark PFS at 6 months
Endpoint domain: Mortality/survival
Primary endpoint: Delta Hemoglobin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Motor function as measured by Dyskinetic Cerebral Palsy Functional Impact Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Gastrointestinal assessment as measured by the Bristol Stool Chart
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Proportion of patients requiring anti-viral treatment
Endpoint domain: Adverse events/effects
Primary endpoint: Change From Baseline in the UAS7
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Per protocol completion rate
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Intent-to-treat completion rate
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Participant satisfaction score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Time to perform TAP Block
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Pain Score Visual Analog Scale (VAS) 0 Hours Post Surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fall Efficacy Scale
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Maximum Expiratory Pressure (PEmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Maximum Inspiratory Pressure (PImax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Surface electromyography (sEMG) Similarity Index (SI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Ocular Surface Disease Index (OSDI) Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Relief Rate of Mammary Gland Pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Taste Assessment scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-anaesthetic discharge scoring
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Kinetics of iron uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change of toleration/wellbeing
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Plasma lutein concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Cognition using the Montreal Cognitive Assessment (MoCA)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Geometric mean concentrations (GMC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Experiences of people using psychedelic substances
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Pharmacokinetics profiles-(AUC0-t)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pharmacokinetics profiles-(Cmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes of serum ALT levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Changes of serum AST levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Normal ASQ-3 score rate
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Normal SDQ score rate
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Normal weight rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Recurrent VTA
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Explanted
Endpoint domain: Mortality/survival
Primary endpoint: Area under the plasma concentration-time curve from time zero to infinity (AUC0-inf) of MB-102
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Correlation of transdermal derived glomerular filtration rate (tGFR) to the plasma-derived indexed glomerular filtration rate (nGFR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: EMG assessment of muscle activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Severity of Mpox lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of hospitalisations
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Percentage of Subjects in CR
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Subjects FC-MRD Negative
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Zarit Burden Interview-Short Form
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Revised Functional Limitations Battery
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Met daily weighing goal
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Met daily active minutes goal
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: At or under daily red foods limit
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Number of participants with detectable viral shedding in nasopharyngeal swab(s)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Number of participants with On-breath volatile markers that correlate with clinical symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants with Biomarker expression changes that correlate with clinical symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Unused opioid prescriptions
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in Traumatic Airway Injury Management Knowledge
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in WAIS-IV Coding Test Score
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Number of Participants With Hypersensitivity Reactions Including Shock and Anaphylaxis
Endpoint domain: Adverse events/effects
Primary endpoint: Time-to-event to achieve WHO level ≤3
Endpoint domain: Mortality/survival
Primary endpoint: Adverse Events (AE) or Serious Adverse Events (SAE)
Endpoint domain: Adverse events/effects
Primary endpoint: Successful aneurysm/PAU treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CaD presence and concentration in nasal mucosa
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CaD presence and concentration in saliva
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes