TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: operative time taken for the surgical removal of impacted lower third molar
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Duration of Treatment (DoT)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Duration of use of nasogastric (NG) tube
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Number of Participants With Medically Attended Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants with AEs of Special Interest, Serious AEs, and AEs Leading to Discontinuation of Study Injection or Study Participation
Endpoint domain: Adverse events/effects
Primary endpoint: Quantity and quality of genetic variants in immunological genes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in the safety management sub-scale of the Epilepsy Self Management Scale (ESMS)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Trained naming items
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Trained comprehension items
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Area under the concentration-curve from time zero to the last quantifiable concentration (AUClast)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual Field Mean Deviation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Prolonged Grief Disorder Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Number of participants who achieve body weight reduction ≥5% from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in total body weight from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Hydration measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of occupational dermato-allergology consultations
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Mindful Attention Awareness Scale (MAAS-15)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: responsive rate of dose escalation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Volumetric bone gain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Lowest SpO2 after emergence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in Engagement in Care
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Onset of sensory analgesia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Long term functional outcomes
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Difficulty in feeding
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Percentage of patients with at least a 20% decrease in nodules
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: delta Esophageal Pressure (ΔPES)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: New biomarkers for diagnosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall safety and tolerability profile
Endpoint domain: Adverse events/effects
Primary endpoint: Preliminary efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of cytokine release syndrome (CRS)
Endpoint domain: Adverse events/effects
Primary endpoint: Care Engagement
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: 12-month freedom from AF recurrence
Endpoint domain: Mortality/survival
Primary endpoint: freedom from a composite of serious adverse events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Digital Game Addiction Scale score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Occurrence of paroxysmal AF
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: THYCA-QoL score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in circulating N-terminal pro-brain natriuretic peptide (NTproBNP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes in stereopsis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Tracheal twitch pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in Diaphragmatic thickness fraction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Changes in plasma osmolality
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in urine specific gravity (USG)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in plasma volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in sweat rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duke Activity Status Index
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Veterans-Specific Activity Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Steep ramp test (peak work rate)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in respiratory strength: maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in functional capacity: 6 minutes walk test (6MWT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Quality of life related with Health (SF-36)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Audiometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Paired associate learning test
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Safety and tolerability of COVID-19 HIPRA vaccine
Endpoint domain: Adverse events/effects
Primary endpoint: Survival Data of Partial Laminate Veneers
Endpoint domain: Mortality/survival
Primary endpoint: maximal organ toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: number of AEs of grade III or greater
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of participation in the CR
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Diagnosis of peri-implantitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lymphatic abnormalities
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Presence of HME-associated adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: MKP-1 activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Foot plantar pressure distribution
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Decrement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Relaxation time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Scan Speed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: FSFI questionnaire score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Shortened second stage of labor
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in maternal blood loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Cost-utility ratio (costs/QALY)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Clinical safety and effectiveness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in radiographic measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: T-lymphocyte levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum Cytokine levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Immunoglobulin A, M, G levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Positive Margin
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: General Cognitive Ability Score
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Core Language Score
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Rezafungin Clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: frequency and severity of device and procedure related adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: within-subject difference between CNC word score at 12-months post-activation and pre-operative aided score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Integrity of the duodenal intestinal barrier
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Degradation of Topoisomerase 2 b
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinical success of pulpotomy treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: % change in Pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sensitivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: specificity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: positive/negative predictive value
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Post-operative Pain
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Functional Shoulder Scale
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Response rate among the randomly sampled participants
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Incidence of respiratory virus detection in symptomatic persons
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Prevalence of post-acute viral symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anatomical knowledge
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Bayley-4 Cognitive Raw Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maternal ferritin concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Otological status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rates of incident DSM-5 mental disorders
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Relapse Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bristol Breastfeeding Assessment Scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Tragus to wall test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Craniovertebral angle assess
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pregnancy Risk Perception Scale (GRP)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Self-Efficacy Scale in Gestational Diabetes (GESGD)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: T.Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Progression-free survival at 6-month
Endpoint domain: Mortality/survival
Primary endpoint: Prevalence and incidence of physical harms
Endpoint domain: Adverse events/effects
Primary endpoint: Prevalence and incidence of psychological harms
Endpoint domain: Adverse events/effects
Primary endpoint: Prevalence and incidence of social harms
Endpoint domain: Adverse events/effects
Primary endpoint: Complete Remission with Incomplete Count Recovery (CRi)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Partial remission rate (PR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: VASA Pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Birth Experience Questionnaire (CEQ)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Oxy-Hemoglobin Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Upper Extremity Function Score of the Korean Version of the Fugl-Meyer Assessment (K-FMA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Grip and Pinch Strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Korean-Modified Barthel Index (K-MBI) score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: final knee range of motion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: incidence of secondary surgery
Endpoint domain: Adverse events/effects
Primary endpoint: Left ventricular outflow tract velocity time integral
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Postoperative Swelling
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in mental health status
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Diagnostic capacity of bpMRI for clinically significant prostate cancer
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Changes in microbial community
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Correlation between clozapine and infections
Endpoint domain: Adverse events/effects
Primary endpoint: Dose Limit Toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Muscle Dynamic Stiffness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Mechanical Stress Relaxation Time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Delivery accuracy of MIIPS 2020
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite of stroke or all-cause mortality
Endpoint domain: Mortality/survival
Primary endpoint: Stroke in the qualifying artery territory
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Participants' ratings of satisfaction with the intervention
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Ratings of Acceptability of intervention to participants
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Immediate energy intake post-fixed lunch meal
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Total delayed post-fixed lunch meal energy intake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Total post-fixed lunch meal energy intake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Transfer Success Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean respiratory system impedance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Proportion of subjects with at least 75% improvement in PASI (PASI 75)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Number of relapses in the past 12 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Baseline ARR (Annualized Relapse Rates)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Markers in adipose tissue dysfunction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Muscular insulin sensitivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Clinical Dementia Rating (CDR) score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Geometric mean titers of anti-SARS-CoV-2 spike IgG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Occurrence of dose-limiting toxicities (DLTs) during Cycle 1
Endpoint domain: Adverse events/effects
Primary endpoint: Occurrence of post-surgical adverse events (AEs) related to BNT116 and cemiplimab
Endpoint domain: Adverse events/effects
Primary endpoint: daily blood glucose concentrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Shoulder Range of Motion in Flexion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Shoulder Range of Motion in Extension
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serious Adverse Device Effect (SADE)-Free Rate at 3 Months
Endpoint domain: Adverse events/effects
Primary endpoint: Implant Success Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Rate of serious adverse event
Endpoint domain: Adverse events/effects
Primary endpoint: Gastrointestinal Symptom Rating Scale-IBS (GSRS-IBS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: IBS quality of life questionnaire (IBS-QoL)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Neoplastic Progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Incidence of grade III to IV aGVHD
Endpoint domain: Adverse events/effects
Primary endpoint: Universal Goniometer for range of motion measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Changes in baseline depressive symptoms
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in baseline test Time up and go
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in baseline balance test, mark speed, and sit and stand chair
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of successful abortions without aspiration or D&E
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in holotranscobalamin
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in methylmalonic acid
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Completed colorectal cancer screening
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Incidence and severity of Treatment-Emergent Adverse Events and Serious Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Mortality Composite Score
Endpoint domain: Mortality/survival
Primary endpoint: Platelet count of ≥ 50 × 10^9/L
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Changes in blood marker levels of inflammation and oxidation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change in plasma volume from baseline to 7 days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in total body water from baseline to 7 days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean area under the log contrast sensitivity function (AULCSF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Metabolic Syndrome Prevalence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Prevalence of primary radial nerve palsy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Memory of therapy content assessed by the Therapy Recall Task
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Feasibility assessed by mean CPT Adherence
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Treatment acceptability after Session 1 assessed by the Credibility and Expectancy (CEQ) questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Device Accuracy - Positive and Negative Percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Device Accuracy - False positive and False negative percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants with Serious Adverse Events (SAEs) and Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Lung Cancer Stigma
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of counts
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Feasibility of repeated BBB disruption
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Seroconversion Rate (SCR) of Hemagglutination inhibition (HAI) antibodies
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of participants with Adverse Reactions (ARs)
Endpoint domain: Adverse events/effects