TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Distribution of nine body constitutions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Placental histological evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the plasma concentration-time curve from time zero to time of the last quantifiable concentration AUC(0-T)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the plasma concentration-time curve from time zero extrapolated to infinite time AUC(INF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of subjects achieving Low Disease Activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cerebrospinal fluid (CSF) valdecoxib concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Non-serious Adverse Events (Non-SAEs) and Serious Adverse Events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Non-progressive Disease (Non-PD) Rate at Week 12
Endpoint domain: Mortality/survival
Primary endpoint: Safety of the WFMA-based cortical interface
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Who Did Not Experience a Flare
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence to current guideline
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Incidence of myocardial injury defined by new Hs-cTnI elevation postoperatively
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of postoperative renal injury using investigational renal biomarkers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: duration of submaximal exercise tolerance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: kilocalories ordered
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Rate of cervical dilatation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Measured levels of cyclobenzaprine and norcyclobenzaprine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety and tolerability of TNX-102 SL Tablets
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of patients with tumor tissue expressing specific target antigens
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Proportion of patients with tumor tissue overexpressing c-MET
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Proportion of patients with tumor tissue expressing a predefined gene-expression signature
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Identification of active bleeding
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Change in the Basophil Proteome
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in number of suicide attempts/self-harming acts
Endpoint domain: Adverse events/effects
Primary endpoint: Clinical Improvement of Negative Symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quantitative measure of neck strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Percentage of Participants Who Did Not Require a Rescue Sedative
Endpoint domain: Adverse events/effects
Primary endpoint: Social and Occupational Functioning Assessment Scale (SOFAS) Scores
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: 3-months WOMAC score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Quality of Recovery
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Wound Healing indices (WHI) assessed on 4th day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Wound Healing indices (WHI) assessed on 7th day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Correlation with clinical outcome after 6 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) Activity Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAE)
Endpoint domain: Adverse events/effects
Primary endpoint: Listening effort
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Stroop Color and Word test
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Rey Complex Figure Test
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Symbol-Digit Modalities Test
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Trail Making Test A and B
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Verbal Fluency Test (category and lexical)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Logical Memory Test A
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Quantification of brain glucose uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Quantification of brain acetoacetate uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Cariogenic bacteria reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Success rate of nasotracheal intubation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Total ventilation time during intensive care unit stay
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: anxiety states
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: cortisol and DHEA levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PSA levels in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Amyloid Deposition
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Time to complete the running course
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Monitoring of pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Monitoring of temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adverse reactions to anesthesia
Endpoint domain: Adverse events/effects
Primary endpoint: Kidney function changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Insulin responsiveness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Progression-free Survival at 6 Months and 12 Months
Endpoint domain: Mortality/survival
Primary endpoint: treatment failure at 72h after initiation of antibiotics
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: in-hospital treatment failure due to multiple causes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: levels of peripheral leukocyte SMN protein
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Changes of serum hs-CRP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Changes of serum TNF-alpha
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Changes of serum IL-6
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Changes of serum IL-10
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Rate of normalized urodynamic findings
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Muscle structure evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Addiction severity
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Physician Observer Scar Assessment Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Blood CK level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CMAS score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Success of the popliteal plexus block
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Diagnosis of joint effusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: methylation changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Secondary Traumatic Stress
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: fatty liver index (FLI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: liver stiffness (LS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Composite outcome measure of calorie, protein, fat, and carbohydrate intake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: High Intensity Service Utilization Rate
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Cognitive profiles in social cognition
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Number of subjects with adverse events following single doses
Endpoint domain: Adverse events/effects
Primary endpoint: Number of subjects with adverse events following multiple doses
Endpoint domain: Adverse events/effects
Primary endpoint: Composite of all-cause death, non-fatal myocardial infarction, non-fatal stroke, stent thrombosis, or urgent revascularization
Endpoint domain: Mortality/survival
Primary endpoint: Percentage and intensity of local and general signs and symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: colour changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of biological activity of serum
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants With ≥50% Pain Reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Participation in exercise (weekly minutes of exercise)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: number of flap failures
Endpoint domain: Adverse events/effects
Primary endpoint: Change in glycaemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Maximum Tolerated Dose (MTD) based on Dose Limiting Toxicities (DLTs)
Endpoint domain: Adverse events/effects
Primary endpoint: Change of the Functional Assessment of Chronic Illness Therapy -Fatigue (FACIT-F) score
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Change of the Pittsburgh Sleep Quality Index (PSQI) score
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Change of the carotid-femoral pulse wave velocity (cfPWV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Survey Completion
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Engagement rate of participants in sending photos via email
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: TEAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Loss of HCV RNA at end of treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Maximum observed plasma concentration of BMS-963272 (Cmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time of maximum observed concentration of BMS-963272 (Tmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the concentration-time curve in one dosing interval (AUC(TAU))
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean Clinical Scoring Scale for dermatitis (CSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Assessment of nasal cavity and nasopharyngeal tissue damage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of rehospitalizations for heart failure exacerbation
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Number of emergency room visits for heart failure exacerbation
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Sustained Virologic Response 24
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Incidence of IgG against SARS-CoV-2
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of participants experiencing toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: Time to Effective Airway
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Reintubation rate at 72 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Maximum tolerated dose based on dose-limiting toxicity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Amount excreted (Ae)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of the administered dose (%Ae)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative recovery (CumAe)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of cumulative recovery of the administered dose (Cum%Ae)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in free-water accumulation in the substantia nigra
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in blood oxygen level-dependent (BOLD) signal in the posterior putamen
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in blood oxygen level-dependent (BOLD) signal in M1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in blood oxygen level-dependent (BOLD) signal in the supplementary motor area (SMA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Rey verbal memory test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stroop Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Area under the curve for phospholipid fatty acids
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Carotid intima-media thickening (IMT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Complete Response (CR)
Endpoint domain: Mortality/survival
Primary endpoint: Serum cystatin C level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of patients alive over the course of treatment
Endpoint domain: Mortality/survival
Primary endpoint: Regional recurrence
Endpoint domain: Mortality/survival
Primary endpoint: Distant recurrence (progression)
Endpoint domain: Mortality/survival
Primary endpoint: Organ-specific excess lifetime attributable risk (LAR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean AUC of beta-cryptoxanthin concentration in blood plasma chylomicrons
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Time to mechanical failure of catheter
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rehospitalization for worsening of heart failure symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Occurrence of serious or non-serious adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Mean Hospital stay
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: shoulder function
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Unified Dystonia Rating Scale (UDRS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Berg Balance Assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fall Efficacy Scale -International
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Anticipatory Postural Adjustment- Compensatory Postural Adjustment measures
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: First time to analgesic requirement
Endpoint domain: Adverse events/effects
Primary endpoint: Average distance to pediatric emergency care
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Diagnosis of sleep disordered breathing
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Preference weight scores for HCC treatment attributes
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Diagnosed with specific cause for chILD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Brain morphometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Systolic Blood Pressure after Normal Saline Infusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Systolic Blood Pressure after 20% Intralipid @ 20cc/hr Infusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Systolic Blood Pressure after 20% Intralipid @ 40cc/hr Infusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Systolic Blood Pressure after Oral 32-gram Fat Load
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Systolic Blood Pressure after Oral 64-gram Fat Load
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: 24 Hour Pain Intensity at Rest
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Resolution of Type 2 Diabetes Mellitus
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Sensitivity of percentage words/phonemes correct
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sensitivity of speech reception threshold for numbers and sentences in noise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sensitivity of aided hearing thresholds
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sensitivity of loudness ratings for narrow band noise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Blood Collection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change of functional decline at 1 month
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Fibrosis reversal based on Fibrotest
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fibrosis reversal based on Hepatic Elastography
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fibrosis reversal based on METAVIR
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety endpoint based on clinical side effects
Endpoint domain: Adverse events/effects
Primary endpoint: Generalised Anxiety
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Cardiopulmonary Exercise Capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: left ventricle end-systolic volume (LVESV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Crown Failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Dental outcomes
Primary endpoint: Rates of fatty acid oxidation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Sleep induction and maintenance
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: First flatus after surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: First stool after surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Hemoglobin level below 11 g/dl
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Urinary excretion of modified nucleosides
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in mean posterior wall common carotid intima-media thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Participants Response Rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Blood oxygen saturations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in bone turnover markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Lesion Activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Smoking Cue Reactivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes