TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Number of Participants With Mycological Efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Comprehensive Efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Systolic Pulmonary Artery Pressure (mmHg) - Mean Change From Baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Diastolic Pulmonary Artery Pressure (mmHg) - Mean Change From Baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Pulmonary Vascular Resistance (Dyne*Sec/cm^5) - Mean Change From Baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Frequency of endometrial contractions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in the frequency of subendometrial contractions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duration of the reduction in subendometrial contractions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With ≥1 Treatment Emergent Adverse Event in Any Category
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With Clinically Relevant Abnormalities in Vital Signs (Pulse, Blood Pressure and Body Temperature)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Clinically Relevant Abnormalities in 12-lead Safety ECG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: ACC visits
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Change in Alcohol Consumption measured by The Timeline Follow-Back (TLFB)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Drinking Intentions as measured by a modified version of the Daily Drinking Questionnaire (DDQ)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Changes in Psychological Well-being Outcomes as measured by the Center for Epidemiological Studies Depression Scale (CES-D)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Number of Participants With Myocardial Necrosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Red blood cell folate status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in serum folate status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: change from baseline dry eye condition at 1 month
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intraoperative corneal clarity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: change from baseline corneal damage at 1 month
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Geometric Mean Titers (GMT) at Day 56
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Tolerance of the form of oral supplementation
Endpoint domain: Adverse events/effects
Primary endpoint: Reduction in SCORAD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Packing Density With the Number of Coils Implanted
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time of Fluoroscopic Exposure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Procedural Device-related Serious Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Cmax of ex vivo IFN-a production by PBMCs, corrected for baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Cmax of ex vivo IL-6 production by PBMCs, corrected for baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Total 30 day post-discharge home opioid use
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Stroke Impact Scale Survey
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Resting State Electroencephalography
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Kinematic Assessment of Performance on finger to nose test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of successful organ transplantation
Endpoint domain: Mortality/survival
Primary endpoint: Proportion of AS assessment responders ASAS20
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence to iron ingot use
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence to oral iron use
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Natural history of hemoglobin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Presence of open breast wound
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Rate of ER visits
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Days to readmission
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Progression Free Survival (PFS) at 12 months
Endpoint domain: Mortality/survival
Primary endpoint: Work stability
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Change in blood vessel diameter after PLM
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Change in blood vessel flow rate after PLM
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: change in lens opacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum tolerated dose of tirapazamine
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Pregnancies Per Year
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Cumulative Pearl Index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: incidence of HCC events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Area under the curve from the time of dosing to infinity [AUC(0-inf)]
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Terminal elimination half life (T1/2)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Control of Diabetes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Control of Hypertension
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Prevalence rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intensity of pain after endodontic treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Use of mental health services
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: number of patients hospitalised for more than 24 hours
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Peripheral blood absolute monocyte/leukocyte count
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: occurrence of Traumatic Dental Injury
Endpoint domain: Adverse events/effects
Primary endpoint: Complete histologic response rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time until clinical improvement or hospital discharge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Who Experienced at Least 1 Adverse Event Causally Related to the Administration of the Study Drug
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants Who Experienced at Least 1 Adverse Event Temporally Related to the Study Drug
Endpoint domain: Adverse events/effects
Primary endpoint: Recurrence of ventral hernia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Palpability of the Restorelle Direct Fix A&P
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Subjects With Meningococcal Serogroup C Serum Bactericidal Titers Equal to or Above Cut-off Value
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Heartbeat
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Improvement in PRAM score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total and relapse-free survival rate
Endpoint domain: Mortality/survival
Primary endpoint: Clinically significant side effect occurrence
Endpoint domain: Adverse events/effects
Primary endpoint: Perceived Stress Scale Scores
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Overall Stent Thrombosis Rate
Endpoint domain: Mortality/survival
Primary endpoint: Integrated pulmoner index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Puls oxymetry
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Heavy Drinking Episodes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hepatic Triglyceride Content Measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Area under the serial Force Expiration volume1 from time 0 to 12 hours (AUC0-12 hours)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Hepatitis B Virus - HBV-DNA less than 20,000 copies/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Alanine Transaminase (ALT) Normalization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-efficacy for diabetes management
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Olfactory identification score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Unstimulated Salivary Flow Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: step counter
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of Functional Independence Measure
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Self-reported abstinence from tobacco
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Cerebral saturation changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ratio of psychoactive drugs/medicines in whole blood-plasma-saliva
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: correlation to symptoms of impairment
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Safety & tolerability of TG100801
Endpoint domain: Adverse events/effects
Primary endpoint: Plasma concentrations of 3TC and 3TC-TP
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diabetes risk as assessed by disposition index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Functional capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Uncorrected Distance Visual Acuity (UCDVA) of 20/20 or Better
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants requiring revision or with Device Related Serious Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Radiographic osteolysis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum TNF alpha AUC (0-28)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Salivary TNF alpha AUC (0-28)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum Interleukin 1 AUC (0-28)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Total Anesthesia NonTechnical Skills (ANTS) Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PedsQL Gastro
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Overall prevalence of HPV subtypes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Number of Participants With Major Bleeding (MB)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With Clinically Relevant Non-Major Bleeding (CRNMB)
Endpoint domain: Adverse events/effects
Primary endpoint: Sexual risk behaviors
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Sputum conversion at 6 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Safety Evaluation assessed by Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Safety Evaluation assessed by Serious Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Safety Evaluation assessed by Tumor Marker Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: CANTAB Spatial Working Memory
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Automated Working Memory Assessment Listening Recall
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: variability in midazolam exposure and response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: variability in morphine exposure and response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Risk of thyroid disease
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Occurrence of Adverse Events (AEs) Leading to Dose Reduction
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Bifidobacterium composition of stool
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Change in Pulse Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in chest pain score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Duration of intravitreal injection procedure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: HIV-1 viral load in throat wash
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: HIV-1 viral load in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Candida CFU level in throat wash
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in fMRI Activation in Participants With Dyslexia Alone (Pseudoword Rhyming and Semantic-category)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in fMRI Activation in Participants With Dyslexia Alone (Stroop Attention Tasks)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in fMRI Activation in Participants With ADHD or ADHD + Dyslexia (Pseudoword Rhyming and Semantic-category Tasks)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in fMRI Activation in Participants With ADHD or ADHD + Dyslexia (Stroop Tasks)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Eye gaze correlates with CAM-ICU
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of a postoperative delirium episode
Endpoint domain: Adverse events/effects
Primary endpoint: Renal Clearance [CL(R)] for AG-348
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Area Under the Concentration-Time Curve From Time Zero to Infinity Concentration [AUC(0-inf)]
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median of systolic 24-hour ambulatory blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Re-operation for recurrence rate
Endpoint domain: Mortality/survival
Primary endpoint: anti-tumor efficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Frequency of HER2 expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Secondary attack rate of influenza and RSV
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Acne vulgaris severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Number of Participants With Either an Infection or a Grade III or IV Adverse Event
Endpoint domain: Adverse events/effects
Primary endpoint: change in emotional balance
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Area Under Curve (AUC)0-t, AUC0-∞
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Tmax
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: t1/2
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Cmax
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: WHO Treatment Emergent Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Non-WHO Listed Treatment Emergent Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: lung ultrasound score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Brain Nicotinamide Adenine Dinucleotide Metabolites NAD+/NADH
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Brain Phosphocreatine (PCr)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Brain Creatine Kinase (CK) Forward Reaction Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Brain Parenchymal pH
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Concentration-time Curve of BI 474121 in Plasma (AUC0-tz)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Measured Concentration of BI 474121 in Plasma (Cmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall response rate as assessed by Independent Review Committee (IRC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Experiencing Treatment-Emergent Serious Adverse Events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Time taken to perform laparoscopic assisted colectomy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Number of surgical steps completed
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Number of operative errors committed
Endpoint domain: Adverse events/effects
Primary endpoint: Subjective Effects
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cold Pressor Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Memory for Medical Information
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Cooking Breakfast task
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Virtual Week task
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in arthritis pain on walking VAS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pupillary variance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Loss of the Retro Placental Sonolucent Zone
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Abnormal Placental Lacunae
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Mean Difference in Monosyllabic Word Scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Functional modified Rankin score at 3 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain measurement using FLACC Pain Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Angle of diplopia deviation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intravascular glucose concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: EGFR mutation detection accuracy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Primary tumor recurrence
Endpoint domain: Mortality/survival
Primary endpoint: Tobacco reduction and abstinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Baseline Brief Psychiatric Rating Scale (BPRS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Health-Related Quality of Life (HRQOL)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: mechanical alignment (MA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: anatomic alignment (AA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: femoral bowing angle (FBA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes