TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Safe recommended phase 2 dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in Glycosylated Hemoglobin (HbA1c) at Week 104
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Blood levels of bioactive metabolites
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Number of differentially expressed immune cell populations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: patient reported fatigue
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Ipsilateral Breast Tumour Recurrence
Endpoint domain: Mortality/survival
Primary endpoint: Index apoptotic (Ratio Bax/Bcl-2) of granulosa cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: GDF9
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BMP15
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in serum Ang-2 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Efficacy of treatment in non-purulent exacerbations of COPD
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in RBANS score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Time to first audible bowel sound
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Balance Measure from force platform (COP Measure)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With First 2 Cycles Dose Limiting Toxicity (DLT) for Combination A
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants With Confirmed Objective Response (OR) as Per RECIST v 1.1 by Investigator Assessment for Combination A
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Difference in intrahepatic lipid (IHL) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Difference in intramyocellular lipid (IMCL) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Triglyceride Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Number of patients with rare adverse drug reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Change in alkaline phosphatase (AP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change in serum glutamic - pyruvic transaminase (SGPT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change in airway resistance at 5HZ (R5)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Percentage of Patients With iPTH Serum Concentration >110 pg/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: urine exosome protein abundance pattern
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: urine electrolyte ratio in a spot urine
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: 24-h urine collection adherence to DASH diet
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Need for endotracheal intubation
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: peptide YY (PYY) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Accuracy of detection of fungal pneumonia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Receptive Language Skills
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Expressive Language Skills
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Time of early onset
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of Craving
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Alterations of the total body composition
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Expiratory pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Modified Rankin Scale (early)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Modified Rankin Scale (late)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Short-Form Healthy Survey Questionnaire (SF-36)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Intraocular pressure smaller than 20 mmHg
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Anxiety
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Depression
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Frequency of menstrually-associated migraine (MAM)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Duration of menstrually-associated migraine (MAM)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Presence or absence of associated symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in cognitive function as measured by ADAS-J cog
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in clinician's impression of change as measured by CIBIC plus-J
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Degree of depression
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Evolution of arterial elastance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Evolution of Stroke Volume (SV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: change in the Medication Appropriateness Index (MAI)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: change in the Assessment of Underutilization (AOU)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of patients meeting eligibility cut-off thresholds
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Percentage of patients who consent to participation
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of logins and time spent on the SPIN-SELF program
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Predictive molecular abnormalities assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change Scores of The Knee Injury and Osteoarthritis Outcome Score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change Scores of The Short Physical Performance Battery (SPPB)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Cognition levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Proportion of patients with proper oropharyngeal airway
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic validity for histological class discrimination
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mortality among AF patients compared with that of the general population
Endpoint domain: Mortality/survival
Primary endpoint: Number of patients with stroke in (non-valvular) AF-patients
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of newly diagnosed patients with (non-valvular) AF per year
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Improved Neuropsychometric Changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Degree of lower urinary tract symptoms (IPSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Occurrence of Severe (Grade 4) Neutropenia
Endpoint domain: Adverse events/effects
Primary endpoint: Maternal hypotension needing vasopressors
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Sensitivity of vh-DNA detection
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Genetic variants contributing to lung cancer risk
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Number of Participants With Physical Examination Abnormalities Reported as TEAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With 12-lead Electrocardiogram (ECG) Abnormalities Reported as TEAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With TEAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Impact on intestinal environment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Number of Participants With New Crime
Endpoint domain: Adverse events/effects
Primary endpoint: Decrease in the dose of vasopressors
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: type and number of genetic abnormalities
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvements in Pulmonary parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Improvements in Cardiovascular parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in ejection fraction (EF(%))
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Endothelial Function (Brachial Artery Reactivity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Time Taken to Complete a Sentence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Circumferences of the affected and unaffected side
Endpoint domain: Physiological/clinical
Endpoint subdomain: Lymphatic system outcomes
Primary endpoint: Rate of symptomatic radiation pneumonitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Reduction in AF burden after ablation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Time to recurrence of persistent AF
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Slope of 25 OH vitamin D3 level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Average hours of CPAP use per night
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Distance from nasopharynx surface to closest wall of internal carotid artery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in lifestyle behaviours
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Time to Transplant Engraftment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequencies of Viral Shedding
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Number of Participants Reporting Solicited Injection-Site or Systemic Reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Change in frequency of the cluster headache attacks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in intensity of the cluster headache attacks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of ECGs abnormalities
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes of the subjects' quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Changes of the subjects' physiological needs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: American Orthopaedic Foot and Ankle Society (AOFAS) score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Objective Response Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Measurement of CD4/CD8 T lymphocyte subsets
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Pharmacokinetics of 6-MP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Pathological complete response of breast and lymph nodes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Length of intraluminal filling defect on CTA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Recurrence of actinic keratosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Target Lesions with IGA Score of 0 or 1
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duration without catheter
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Liver Iron Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Whole blood collection volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Average Sitting Diastolic Blood Pressure (DBP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Percentage of successful placements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Placebo magnitude
Endpoint domain: Adverse events/effects
Primary endpoint: Nocebo magnitude
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Attending the Recommended Number of Postnatal Care Appointments
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Number of Participants Practicing Exclusive Breastfeeding at 3 Months Postpartum
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Number of Participants Using Effective Modern Contraception at 8 Months Postpartum
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Improvement in Shoulder Function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Success of sensory block level at T6
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time-interval weighted summed pain intensity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Complete response rate in prostatectomy specimens
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Improvement in internal rotation of the shoulder
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in Performance of Daily Activities
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Percentage of Average Maximum Heart Rate During Exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Patient Observer Scar Scale
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: number of patients who successfully complete 2 IA injections
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ZincProtoporphyrinIX measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Estimated Two-year Event-free Survival (EFS)
Endpoint domain: Mortality/survival
Primary endpoint: RO5323441 concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adjusted Performance
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Number of device-initiated ventricular defibrillations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of anti-tachycardia pacing events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Macrophage/monocyte HO-1 protein levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Rate of preterm pre-eclampsia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Documented heart disease checklist
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Histological cirrhosis checklist
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver outcomes
Primary endpoint: Hepatocellular carcinoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: arrhythmic event
Endpoint domain: Adverse events/effects
Primary endpoint: Total Score of the Scale Of Prodromal Symptoms
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: change of intra ocular pressure (IOP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Fistula healing rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: tear cytokine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of grade II-IV graft versus host disease (GVHD)
Endpoint domain: Adverse events/effects
Primary endpoint: Changes in Physical Function
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Pressure at Zero Volume (PV0)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Abdominal Elastance (E)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: rate of post-collection TU-to-testosterone conversion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Proportion of Neonate Survival at Discharge From Hospital
Endpoint domain: Mortality/survival
Primary endpoint: Participants Requiring Supplemental Oxygen
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Mean ETDRS visual acuity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Liver Recovery Rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total Bilirubin Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: INR Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Extent and intensity of C11-Erlotinib accumulation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Absolute Change in Facial Inflammatory Lesion Counts at Week 12
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants With Investigator Global Assessment (IGA) Success at Week 12
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in incontinent episode frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Prevalence and relative abundance of selected fecal microbial taxa
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Clinically Significant Hematology Laboratory Abnormalities
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Maximum Post-Baseline Values: Liver Enzymes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Worst Post-Baseline Values for Urinalysis Parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: response rate at the end of therapy protocol
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: risk of respiratory failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Adherence to physical activity regimen
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Motor Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: HIV shedding
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Change in urinary protein/creatinine ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Brain Measures
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of patients with pathological downstaging
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Proportion of patients with biochemical treatment response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Progression Free Survival rate at 6 months
Endpoint domain: Mortality/survival
Primary endpoint: Clinical Response by RECIST Criteria
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Severity of Myasthenia Gravis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in T Cell subtypes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: E/e' (Early Mitral Inflow Doppler Velocity to the Early Diastolic Mitral Annulus Velocity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Stable or Improved Predicted Forced Expiratory Volume 1 (FEV-1)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Improved, Stable or Declined Forced Expiratory Volume 1 (FEV-1) Slope at 6 Months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: intensity of low back pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes