TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Mean change in total YMRS score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence With Intervention
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Number of Participants With Adverse Treatment-altering Events
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Plasma Nitrate Levels, Micromoles/Liter
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Plasma Nitrite Levels, Micromoles/Liter
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Incidence of Inhibitory Antibodies Against Coagulation Factor IX
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Incidence of all Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of deaths due to AEs
Endpoint domain: Adverse events/effects
Primary endpoint: Cardiac Tamponade
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Pericardiocentesis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Change in number of binge drinking days
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Any stroke or death within 30 days after the stenting procedure
Endpoint domain: Mortality/survival
Primary endpoint: Number of Participants Successfully Consuming Peanut Protein
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of change in estimated glomerular filtration rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Rate of change in albuminuria
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Safety of PB103
Endpoint domain: Adverse events/effects
Primary endpoint: Measure of Symptom Change
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Infection rate in mosquitoes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Absolute Percent Change in Written Naming (Trained Items)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Absolute Percent Change in Written Naming (Untrained Items)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Absolute Percent Change in Oral Naming (Trained Items)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Absolute Percent Change in Oral Naming (Untrained Items)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Running skill assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Weight transferring skill assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hand dribbling skill assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Underhand catching skill assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: FitnessGram test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Daily physical activity participation in minutes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cognitive, motivational and decision-making behaviors
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Changes in pulse pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Phenotypic variation due to genetic polymorphisms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain Visual Analog Scale Change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Experiencing Sudden Cardiac Death (SCD)
Endpoint domain: Mortality/survival
Primary endpoint: Changes from baseline in 24-hour insulin requirements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change of EROA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Communications regarding family health history and risk for disease
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Beliefs about the causes and controllability of disease onset
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Development of strategies to adopt health promoting behaviors
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Microbiome alterations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: New or re-emergence of oral lesion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: oral cancer diagnosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Body appreciation
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Body dysmorphic disorder symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Functionality appreciation
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: MRI measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: TCTD measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Survival (OS) for participants with relapsed/refractory multiple myeloma (RRMM)
Endpoint domain: Mortality/survival
Primary endpoint: Overall Survival (OS) for participants with newly-diagnosed multiple myeloma (NDMM)
Endpoint domain: Mortality/survival
Primary endpoint: Progression-Free Survival (PFS) for participants with relapsed/refractory multiple myeloma (RRMM)
Endpoint domain: Mortality/survival
Primary endpoint: Progression-Free Survival (PFS) for participants with newly-diagnosed multiple myeloma (NDMM)
Endpoint domain: Mortality/survival
Primary endpoint: Change on the 17-item Hamilton Rating Scale for Depression (HRSD-17)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in visual acuity of the amblyopic eye
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Clinical Renal Function Lab Abnormalities
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Rate of Device- or Procedure-Related Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Death (age of onset and cause)
Endpoint domain: Mortality/survival
Primary endpoint: Percentage of subjects achieving seroprotection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Percentage of subjects achieving seroconversion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Efficacy (immune response of COVID vaccines)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: blood count
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Expression profiling of circulating microRNAs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Inflammatory responses of cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: 30 day open vascular surgery free rate
Endpoint domain: Mortality/survival
Primary endpoint: Change in vaginal dryness from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Reproductive system and breast outcomes
Primary endpoint: Change in frequency of involuntary urination (urinary incontinence) from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Change in frequency of involuntary urination during physical activities (stress urinary incontinence)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Number of incontinence episodes per day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of Biopsy Proven Acute Rejection (BPAR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Percentage of Participants with Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Gross Motor Function Measure (GMFM) score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: safety and efficacy of SmartPill
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Opioid Usage After Surgery
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Percentage of Participants With Clinical Remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate and degree of OHSS
Endpoint domain: Adverse events/effects
Primary endpoint: scan grade
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: thickness of trunk stabilizer muscles
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: the degree of loss of functionality in low back pain
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: The score of quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Phenotype severity classes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Global gene expression profiles
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Healthcare services utilization
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Changes in Circulating Tumor Cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: differences in elasticity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: differences in compliance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: skin phenotype variability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change in sTfR
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Mean Change From Baseline in UAS7 at Week 12 (Multiple Imputation) of Adult Subjects
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean Change From Baseline in UAS7 at Week 12 (Observed Data) of Adolescent Subjects (FAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Salivary Cortisol levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Neuroelectric outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Academic Achievement outcome
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Postoperative surgical site pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative tourniquet site pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Experiencing Grade 3, 4, or 5 Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: change in baseline hypoglycemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Treatment discontinuation rate due to treatment-related adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Severity of Mouth Pain Scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of postoperative surgical site infections
Endpoint domain: Adverse events/effects
Primary endpoint: Cerebrovascular complication after interventional therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Incidence of in-stent stenosis after stent deployment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Liver triglycerides
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: AUC 0-inf
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Radiographic Response Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in skin thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: metabolic stability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Mean Change of Collateral Circulation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Umbilical artery doppler
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of Surviving Participants That Completed the Study
Endpoint domain: Mortality/survival
Primary endpoint: Kansas City Cardiomyopathy Questionnaire (KCCQ)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: AUClast of Telmisartan and S-amlodipine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax of Telmisartan and S-amlodipine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Learning and memory change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ocular subjective symptoms
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Ocular objective symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Portal vein thrombosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Clavien-Dindo classification of surgical complications
Endpoint domain: Adverse events/effects
Primary endpoint: Chemotherapy Toxicity (%FN Risk)
Endpoint domain: Adverse events/effects
Primary endpoint: Absolute Neutrophil Count (ANC) Across All Cycles
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Number of Participants With All-cause Mortality by Any/no Grade 4 CIN and/or FN
Endpoint domain: Mortality/survival
Primary endpoint: Occurrence of treatment-emergent adverse events (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Reasonable causal relationship between darolutamide and an adverse event (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: Action taken related to darolutamide treatment
Endpoint domain: Adverse events/effects
Primary endpoint: Adverse Reactions (ARs)
Endpoint domain: Adverse events/effects
Primary endpoint: Serious Adverse Reactions (SARs)
Endpoint domain: Adverse events/effects
Primary endpoint: Force error in the precision grip task
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Handwriting task performance
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Brief Resilience Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Nottingham Health Profile
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Mindful Attention Awareness Scale
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Body Awareness Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Richard-Campbell Sleep Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Lateral bridge test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants with Clinical Fractures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Number of Participants With Recanalization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in SF-36 Score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in Fatigue Severity Scale Score
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Change in Beck Depression Inventory Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: PCR adjusted efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Parental quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Family function
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Multifocal Electroretinogram Amplitudes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinical index score (CIS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in mentalizing brain network functional connectivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Incidence of lymphedema of arm and hand
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Deterioration of dermal backflow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Volumetric Response Rate to Treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Inherited immunodeficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Blood Pressure (Systolic)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Muscle Rigidity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Environmental risk exposure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reliance Rate
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of Participants in Remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in SARS-CoV-2 Testing Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in SARS-CoV-2 Test Positivity Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Apnea-hypopnea index (AHI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Incidence of Any Grade Cytokine Release Syndrome (CRS)
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of Clinical Episodes of Malaria
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Interleukin 6 measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Tumor necrosis factor determination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Ventilation In-homogeneity using lung clearance index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Neurocognitive function using a standardized score
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Health Related Quality of Life as measured by PedsQL
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Functional Status as measured by the pediatric functional status scale
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Change in insulin concentration in blood during the cephalic phase of insulin secretion in healthy individuals
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change in insulin concentration in blood during the cephalic phase of insulin secretion in obese patients with type 2 diabetes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Thigh muscle hypertrophy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Near final height (NFH) standard deviation score (SDS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: spinal cord gray matter area
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mental health inpatient days
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Number of suicides
Endpoint domain: Mortality/survival
Primary endpoint: iRECIST Clinical Benefit Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Frequency of Adverse Events (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: Change in DXA score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the plasma concentration versus time curve (AUC) of ENG
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma maximum concentration (Cmax) of ENG
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma minimum concentration (Cmin) of ENG
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to maximum concentration (Tmax) of ENG
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: short-term complete response rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: long-term complete response rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CNS metabolic changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Hamilton Depression Rating Scale (HDRS) score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: motor scales
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: quality of life scales
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: biomarkers from blood and urine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants With at Least 30 Percent Reduction in Blood Phenylalanine Level
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes