TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Objective response per iRECIST
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Percent Married at 12 Months
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Couples' average report of relationship happiness at 12 Months
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Individual psychological distress at 12 Months
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Anti-SARS-Cov2 seroconversion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in Cough Frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall response rate to therapy with ribavirin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Block onset Time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: proportion of post-operative chemo-radiotherapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Pharmacokinetics of erlotinib
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ST segment depression on ECG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Bone Mineral Density (BMD) of the Total Hip and Spine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Implant outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sustained Weight Loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in blood nicotine levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change in average cigarettes smoked per day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Average NJOY Kings puffs used per day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Urinary Tract Infection
Endpoint domain: Adverse events/effects
Primary endpoint: Differentiation of bacterial and viral infections
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Neuronal activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Bowel function Index (BFI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Circumference of the affected limb on hospital admission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of representative biopsies for diagnostic purposes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Change From Baseline in EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of NCI CTC Toxicity III°/IV°
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of severe bleedings
Endpoint domain: Adverse events/effects
Primary endpoint: Maximal Administered Dose (MAD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma concentration of simvastatin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diagnostic accuracy of ImmunoXpert™
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Keratinized Tissue Width
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Task performance (response time)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants achieving RVNA titer ≥ lower limit of quantification
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Geometric Mean Titer Ratio (GMTR) of individual RVNA titer (post-/pre-vaccination)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: QuIC-A score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Linear and angular positioning of the brackets
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Need of Any Blood Products Transfusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Hamilton Anxiety Scale (HAM-A) Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Number of Adverse Drug Reactions/Serious Adverse Drug Reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Fecal continence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Lower extremity functional
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Surgical scarring
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Global satisfaction of the surgery
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Increase in savings balance
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Short-term postoperative pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Treatment Engagement
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Post-surgical Pain Rating Using the Visual Analog Scale (VAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-surgical Opioid Utilization Using Electronic Medication Review
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in Y Balance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Single-Leg-Stance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Lower Extremity Motor Coordination Test (LEMOCOT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Pedalo Sensamove Balance Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Progression-free Survival at Six Months (PFS6)
Endpoint domain: Mortality/survival
Primary endpoint: Steady state plasma DTG pharmacokinetics (PK) parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Objective pathologic response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Objective imaging response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants Free of Live Head Lice and Free of Viable Eggs
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: acute safety of intravenously injected trace dose of [18F]F-AraG
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion non-pregnant subjects virally suppressed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of pregnant subjects who adhere to ART
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: number of patients with calprotectin elevation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes from baseline in systolic and diastolic blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Bone Pain Related Quality of Life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Percentage of P-glycoprotein-positive specimens found negative by efflux assay
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants with pericardial effusion with or without tamponade
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with Electrode Dislocation
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with Bleeding complications
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with Infections complications
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with access site complications
Endpoint domain: Adverse events/effects
Primary endpoint: Number of participants with Pneumothorax
Endpoint domain: Adverse events/effects
Primary endpoint: Change from baseline of alveolar ridge thickness at 4 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline of radiographic bone level on CBCT at 1 year post-op
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline of radiographic bone level assessment at 1 year post-op, on periapical x-ray
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline of bone plate thickness at 4 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Polymorphism in the KISS1/GPR54 pathway genes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Genetic profile shift
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Percentage of ventricular pacing
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Atrial Fibrillation/Atrial Arrhythmia Evolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Cardiac Function Evolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Opioid-Related Adverse Effects
Endpoint domain: Adverse events/effects
Primary endpoint: Excitability of weak muscle pathways
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Reduction in size of wound
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Agreement between AHI measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: response rate of neoadjuvant chemotherapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of PFO in children with migraine headaches
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Kappa agreement on anal exam results
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fetal position assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Estimated reoperations rate at 10 years follow-up
Endpoint domain: Mortality/survival
Primary endpoint: Proportion of patients experiencing financial difficulties
Endpoint domain: Life impact
Endpoint subdomain: Societal/carer burden
Primary endpoint: Depression as measured by the CES-D
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: PHQ-9 (depression) score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Correlation of BIS and PSI
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of thirst intensity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Chronic pain after two years
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Oseltamivir carboxylate levels (Cmax and AUC(0-12))
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Toxicity/feasibility
Endpoint domain: Adverse events/effects
Primary endpoint: Decrease in tumor cell proliferation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Differential change in suicidal ideation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Necessity to perform endotracheal intubation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Disclosure rates for social needs questions
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Correlation between usual physical exercise tests and exercise test measured via mobile COPD status test app
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Knee Osteoarthritis Outcome Score (KOOS) Pain Subscale
Endpoint domain: Life impact
Endpoint subdomain: Pain
Primary endpoint: Ocular surface index score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of migraine headache days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Side effects and toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: changes in neurocognitive test scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: changes in measures of community functioning
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Knee implant survivorship
Endpoint domain: Mortality/survival
Primary endpoint: Proportion of subjects achieving sustained virologic response (SVR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Susceptibility to filarial infection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Development of filarial disease
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Response to chemotherapy
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Lumbar Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in Femoral Neck Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in Trochanter Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in Hip Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Number of Patients Eligible Compared to the Number Approached and Enrolled
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Changes in the Saint George's Respiratory Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Achieving 30 minutes of daily exercise, four or more times each week
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Patients With Adverse Events (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: Skin microvascular blood flow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: awake systolic blood pressure (SBP) changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: sleep systolic blood pressure (SBP) changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: oxygen desaturation index (ODI) changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: episodes of cholangitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Sensory and motor block
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Average FLACC Pain Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Successful collection of HMR imaging data
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: VCAM-1 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants With Negative Cough Stress Test (CST)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinically significant changes in laboratory tests
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Cough reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Performance Evaluation of Perimount Heart Valve
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Safety and efficacy of Nasogastric/Orogastric tube placement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Recognition of anatomical markers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Critical errors
Endpoint domain: Adverse events/effects
Primary endpoint: Progression-free Survival Rate at Weeks 17 and 25
Endpoint domain: Mortality/survival
Primary endpoint: Objective Response Rate at Weeks 17 and 25
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: proportion of patients who could withdraw from prednisone and hydrocortisone
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Utilisation in terms of dose and dosing interval
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: SARS-CoV-2 reinfection rate
Endpoint domain: Adverse events/effects
Primary endpoint: Blood level of AMH
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Basal level of AMH
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Detection rates of specific tissular miRNAs in blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Detection of diabetic nephropathy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Area Under the Curve (AUC[0-24 h])
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Half-life (T[1/2])
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Weekly Change in 24-Hour Average Pain Rating
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in the UPDRS-III Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: FEV1 area under the curve (0-12 hours)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Peak FEV1 after 6 weeks of treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Rate of Change in Intentions for Mammography
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Ammonia plasma concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Recurrence of atrial fibrillation/atrial tachycardia/atrial flutter
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Appearance of Scar
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Mouth-opening odds ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Auto-CPAP pressure level odds ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Sleep position odds ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Respiratory effort (increase in the Jawac signal > 0.3 mm) odds ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Reduction in Acute Per-prostatic Rectal Ulcer Events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Effectiveness of Space Creation in Protecting Rectum From Toxicity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of HIV and STI self-test kits delivered
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Intracellular tenofovir diphosphate levels in dried blood spots
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of thromboembolic events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Clinical Global Impression - Severity scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Area under the serum concentration (AUC) versus time curve from zero to last quantifiable concentration [AUC(0-last)]
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the concentration-time curve in serum from time zero extrapolated to infinity [AUC(0-inf)]
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Confirmation of sentinel lymph node at surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Lymphatic system outcomes
Primary endpoint: Incidence of immune related adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of acute and late radiation toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Accuracy compared with ground truth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sero-prevalence of Bordetella pertussis infection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: anti-PT antibody levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: anti-PT seropositivity status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: anti-PT seronegativity status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: clearance of the parasite
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Cornea and conjunctiva staining (Oxford score)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reliability of NKI i-PAS signals
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Escore of combined risk factor control
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in total liver fat fraction by Magnetic resonance imaging (MRI) from baseline to 12 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Sleep Functioning
Endpoint domain: Life impact
Endpoint subdomain: Sleep