TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Antral motility inhibition
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Motilin secretion inhibition
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Cholecystokinin (CCK) secretion increase
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Area under curve (AUC0-24)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quality of life of residents
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Epithelialization at 7 days after extraction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Wound healing outcomes
Primary endpoint: Angiogenesis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Regular use of contraceptives
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean number of capsules taken daily
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Contrast-induced nephropathy diagnosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Mean creatinine value
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Mean trapezius muscle activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Serum concentrations of metabolites
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Area of demineralization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cure rate against C. sinensis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Cure rate for hookworm
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: AVNRT recurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: immediate ablation failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: permanent AV block
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in International Prostate Symptom Score (IPSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Accuracy in incongruent trials
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lengths of ICU and post-ICU stay
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: graft failure rate
Endpoint domain: Mortality/survival
Primary endpoint: FFI values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: hind foot AOFAS scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ankle proprioception sense
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: functional oral intake
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: communication abilities
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: speech intelligibility
Endpoint domain: Life impact
Endpoint subdomain: Communication functioning
Primary endpoint: Severity of GI symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Negative impact of side effects on routine activities
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: IL-18 mRNA expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: SLAM mRNA expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: self-reported anger scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: staff ratings of patient behaviour
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improvement in general well-being
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: % body fat change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Aerobic performance change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improved AV
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduced plasma leptin concentrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Increased VO2peak
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 6-km time-trial performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: incidence of abdominal complications
Endpoint domain: Adverse events/effects
Primary endpoint: incidence of pancreatic fistulas
Endpoint domain: Adverse events/effects
Primary endpoint: 5-year Disease-Specific Survival (DSS)
Endpoint domain: Mortality/survival
Primary endpoint: 5-year Recurrence-Free Survival (RFS)
Endpoint domain: Mortality/survival
Primary endpoint: uptake of a mental health outreach program
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in CH3 SH readings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in H2 S readings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in ADAS cog score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in NPI score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Need for anti-diarrheal medication
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Positive responses during testing phases
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sensitivity of the protocols
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Specificity of the protocols
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: decreased pain intensity during motion at 24 h post-operatively
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: total quality of recovery 40 questionnaire score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: analgesic satisfaction
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: high frequency norm of HRV
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Surgical time efficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Physician certainty in prescribing iv-tPA
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Accuracy of lung nodule volumetry
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Positive rate of p53 and p63 protein expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Reduction of plasma glucose
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Proportion of participants with HIV‐1 RNA ≥50 copies/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Local recurrence (LR) incidence
Endpoint domain: Mortality/survival
Primary endpoint: improved blood glucose control
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: improved daily functioning
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Surface roughness of Ionofil U
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Willingness to use microbicides
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Clinical Global Impression of Improvement scale responses
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Improvement in oral health behaviours
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Assessment of eligibility
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Assessment of potential benefit from trial therapy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Risk of nonvertebral fractures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Coronary collateral conductance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: plaque growth inhibition
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Estimated Glomerular Filtration Rate (GFR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Antibody titers ≥1:8
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Percentage of participants positive for EV71-IgM
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: RVV seroconversion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Antibiotic susceptibility
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: peak amplitude of EMG burst of RMMA episodes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: self-reported reduction of tooth grinding
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: self-reported reduction of morning jaw stiffness
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Development of shock
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: knowledge scores about treatment options
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: MRC-Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of ICU-AW
Endpoint domain: Adverse events/effects
Primary endpoint: Improvement in students' KSAs regarding safety in health care
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Functional Ambulation Profile score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Walking work economy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Root mean square of vertical acceleration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Metabolic syndrome scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Discrepancies resolved in the first 48 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 30-day favorable functional outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 90-day negligible dependence
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Repeated exercise performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: incidence of lower UTI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Transfusion utilization
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Length of stay in the hospital
Endpoint domain: Resource use
Primary endpoint: total pulmonary resistance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Time to all-cause death or cardiovascular or renal hospitalization
Endpoint domain: Mortality/survival
Primary endpoint: radionuclide clearance retention
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Increase in subjective anxiety
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increase in panic symptom scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: rate of response to BA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient accountability
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Sustain behavior change
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Improvement >10 mm on the PGA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total MRSS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of patients who failed medical therapy and were deemed surgical candidates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in RSDI scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in CSS scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: T4 AUC
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Improvement of gingival health
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ejaculations per week/satisfaction with sex life
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Scores of concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum lipoprotein levels (TC, HDL-C, LDL-C, TG)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Insulin levels and HOMA scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: risk of treatment failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: overall 10-year survival
Endpoint domain: Mortality/survival
Primary endpoint: PCa incidence
Endpoint domain: Mortality/survival
Primary endpoint: lower urinary tract symptoms
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Mean change in predicted FEV1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: GRD decrease
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ACL mean gain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: LENT/SOMA scale scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: function/bother scale scores
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: clinic attendance rates
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Active Ankle Dorsiflexion Range of Motion (AADFROM)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Implementation of palliative care policy
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: mean additional cost per patient over 3 years
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Success rate in weaning off RAM NC
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma and serum uric acid levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Tophus resolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Flare incidence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual analog scale for pain
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Serum BDNF concentrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 2-year risk of progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Progression of central visual field defects
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Presence of mature biofilm
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Epinephrine concentrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Total TS activity in cancer tissues
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of TS inhibition in cancer tissues
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of parturient that required ephedrine
Endpoint domain: Adverse events/effects
Primary endpoint: improvements in SF-36 social functioning
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: improvements in mental health scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: improvements in pain quality scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 8‐iso‐PGF(2alpha) urinary excretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: 11‐dehydro‐thromboxane B(2) urinary excretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Detection of definitive glaucoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: No deaths
Endpoint domain: Mortality/survival
Primary endpoint: No intensive care unit admittances
Endpoint domain: Adverse events/effects
Primary endpoint: SAR symptom severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Decrease in breast volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall satisfaction about the reconstructed breast
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Painfulness scores
Endpoint domain: Adverse events/effects
Primary endpoint: Pain reduction during local anesthetic injections
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in SF-36 mental health domain scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in SF-36 physical health domain scores
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: 30‐second Chair Stand Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Insulin demand
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Gastrointestinal intolerance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Postpartum blood loss at 1 hour after delivery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Frequency of moderate PPH (500‐999 mL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: proportion of patients with neovascular complications
Endpoint domain: Adverse events/effects
Primary endpoint: overall voicing
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: ease and effectiveness of cleaning
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Pain assessment improvement
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Mean serum zinc levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Reduction in ventilatory requirements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Earlier diuresis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: SBS values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean time from incident infection to development of VIN 1-3
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: pre-dinner blood glucose values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postural stability in monopedal stance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postural stability in bipedal stance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fullerton Advanced Balance Scale score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Knowledge of HCC and hepatitis B
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: PG-YBOCS total score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Morphine equivalent daily dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence scores
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: urgent reintervention (rePCI)
Endpoint domain: Mortality/survival
Primary endpoint: Responder rate in the Mini Balance Evaluation Systems Test subscore reactive postural control
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median time to arrival at the mannequin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median value of the total searched area
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median area searched per minute
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Vitamin D status
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Isokinetic dynamometer strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: suicidal ideation rates
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: 24-h urinary CTX-II excretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 24-h urinary CTX-I excretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes