TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: total headache activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: headache-free days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Freedom from primary thromboembolism
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean pressure gradient values
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: months without disease relapse
Endpoint domain: Mortality/survival
Primary endpoint: months of moderate or worse toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: Central retinal thickness (CRT) change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of clinically significant pseudophakic cystoid macular oedema (PCME)
Endpoint domain: Adverse events/effects
Primary endpoint: language development
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Average saving with PHACO compared to ECCE
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Plasma level of P-selectin
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: TXB2 concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: self-reported analgesic use
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: angles of abduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of pulmonary hypertensive crises
Endpoint domain: Adverse events/effects
Primary endpoint: OSCE results
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mood disturbance
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: spirituality
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Hemoglobin concentrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Iron deficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Vitamin A deficiency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Forced expiratory flow between 25% and 75% of vital capacity (FEF(25%-75%))
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Diffusing capacity of the lungs for carbon monoxide (DLCO)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Total improvement rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative score of UPDRS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ST-segment resolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Myocardial blush grade
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Immunogenicity detection rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cumulative infliximab dose
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Drug cost
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Care quality
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: TNF‐α levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ADPN levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Condition-specific quality of life improvements
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Cumulative primary patency rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Overall cumulative limb salvage
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: COX/CS ratio improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Thrombolytic failure
Endpoint domain: Adverse events/effects
Primary endpoint: Total opioid consumption
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Consumption of analgesic drugs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Seroma occurrence
Endpoint domain: Adverse events/effects
Primary endpoint: LDL-cholesterol levels reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: hs-CRP levels reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: self-esteem
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Cost per life-year gained
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Feelings of hunger
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Sensation of epigastric distension
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Repeat Recurrence-Free Survival (rRFS) rates
Endpoint domain: Mortality/survival
Primary endpoint: Successful first-pass intubation rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Severe life-threatening complications
Endpoint domain: Adverse events/effects
Primary endpoint: Transverse dental arch relationships
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Spasticity of the paretic knee
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neuromuscular outcomes
Primary endpoint: 1-year cardiac mortality
Endpoint domain: Mortality/survival
Primary endpoint: 1-year myocardial infarction (MI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: mean oxyhemoglobin saturation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: total arousal index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Sexual arousal
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Perceived disinhibition
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Viewing behavior
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: simple task mobility test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Integral quality-of-life indicator
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: infants with healthy weight-for-age measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: breastfeed exclusively for six months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improved cognitive development at 18 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Physical component score of the SF-36
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: comfort level
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Respiratory Disturbance Index (RDI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Patient compliance (nights per week of mask appliance)
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: SF‐36 scale of health
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: satisfaction scores for nursing work
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Increased daily steps
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: total awake 'Off-time'
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: absolute awake time spent 'On' without troublesome dyskinesia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Unified Parkinson's Disease Rating Scale motor scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Kansas City Cardiomyopathy Questionnaire (KCCQ) scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: B-type natriuretic peptide (BNP) levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Proportions of patients maintaining antibody responses
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: number of dermal papillae
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: fibroblasts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: vessels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Physeal fibular injury
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Metaphyseal fibular injury
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Need for dialysis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Need for ventilatory support
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Daily NPS reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Left ventricular end-diastolic volume index reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Left ventricular end-systolic volume index reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Left ventricular mass index regression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Knowledge about fertility
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Awareness of preconception health
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Craving relief
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Shear bond strength (SBS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ACR 20 responders
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: EULAR responders
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: death rate before or on Day 28
Endpoint domain: Mortality/survival
Primary endpoint: forced vital capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: plasma prostacyclin levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: plasma leukotriene levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Qmax improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: tolerance at 1 week
Endpoint domain: Adverse events/effects
Primary endpoint: clinically significant varices
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: ESS improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean MWT sleep latency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CGI-C improvement
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change from baseline in AHI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Turbinate edema and nasal obstruction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Nasal volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Elimination rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Low density lipoprotein (LDL)‐cholesterol levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: High density lipoprotein (HDL)‐cholesterol levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Inflammatory markers (IL-6 and TNF-α)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: infiltration rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: cannulation time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: subpopulation treatment effect pattern analysis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 5-year failure-free survival rate
Endpoint domain: Mortality/survival
Primary endpoint: 5-year cumulative survival rate without chipping
Endpoint domain: Mortality/survival
Primary endpoint: 5-year cumulative survival rate without debonding
Endpoint domain: Mortality/survival
Primary endpoint: Ejection fraction estimation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Subcutaneous fat reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: EEG coherence levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: RAL gain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction of deep pockets
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cervical flexion active ROM
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cervical extension active ROM
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Roland‐Morris Disability Questionnaire scores
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Time to successful tracheal intubation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Leak pressures
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Major adverse cardiac events (MACE) rate
Endpoint domain: Adverse events/effects
Primary endpoint: Target lesion revascularization (TLR) rate
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of patients achieving mean diurnal IOP ≤15 mm Hg
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: escalation of care
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Oral hygiene compliance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC(0-t) for cyclophosphamide
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC(0-t) for 4-OH metabolite
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUC(0-t) for DCE
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Aortic systolic pressure decrease
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Improvement in MBI
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Falls Efficacy Scale score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Psychiatric morbidity
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: T cell response to Japanese cedar pollen
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Amygdala and posterior hippocampus activation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: intention to receive the HPV vaccine
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: vaccine uptake behaviour
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: %Δ insulin enhancements
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: %Δ PAI‐1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: %Δ t‐PA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Improvement of parkinsonian signs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: intent to recommend
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: number of days with records
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Vital sign measurements (blood pressure and heart rate)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Quality-adjusted life year
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Quality of life evaluation
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: change from baseline in trough FEV(1) on day 29
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Time to maturity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Potency rates at 12 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Continence rates at 12 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Need for blood transfusion
Endpoint domain: Adverse events/effects
Primary endpoint: urinary albumin excretion (UAE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: academic performance
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: mean change in HbA1c
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: patient-reported outcome scores for social functioning
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: CD4 count decline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: EQ5D based QALYs
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: combined risk of moderate or severe cerebral palsy or death
Endpoint domain: Mortality/survival
Primary endpoint: Death from cancer
Endpoint domain: Mortality/survival
Primary endpoint: Local-regional control
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient compliance
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Systemic toxicity
Endpoint domain: Adverse events/effects
Primary endpoint: Satisfaction with recovery (SRQ)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Total volume of injectate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean heartburn score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: ability to belch
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: satisfaction with outcome
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: postoperative exercise capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: LDL-C reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Triglycerides reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: risky drinking behaviors
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence attitudes
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Adherence behaviours
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Confidence in asthma self-management
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Vision-related quality of life improvement
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Minimum plasma concentration (C(trough))
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma ANP levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Urinary excretion of urodilatin (U(URO)V)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean systemic exposure (AUC) of SMV and SMV-acid
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean peak concentrations (Cmax) of SMV and SMV-acid
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of probable or verified stroke
Endpoint domain: Mortality/survival
Primary endpoint: Cumulative incidence of stroke
Endpoint domain: Mortality/survival
Primary endpoint: incidence of unstable angina episodes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: number of totally occluded vessels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: long-term all-cause mortality
Endpoint domain: Mortality/survival
Primary endpoint: HF events
Endpoint domain: Mortality/survival
Primary endpoint: patient-reported tolerance score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: LDAEP modulation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in glycemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Improvement in lipemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Theophylline use
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: fewer alcohol-related consequences
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes