TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Infection within 1 week before ictus
Endpoint domain: Adverse events/effects
Primary endpoint: Cerebrovascular ischemia risk
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: risk of undergoing later surgical repair
Endpoint domain: Mortality/survival
Primary endpoint: Word recall performance
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: hs-CRP serum levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Plasma levels of proBNP, NT-proBNP, BNP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Degree of plasma proBNP glycosylation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Furin activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative spherical equivalent predictability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Decay into dentine at follow-up
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Qualification for RCTs based on exclusion criteria
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: problem-solving
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: percent change in pain (VAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: endogenous insulin concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Response to treatment based on physician assessment of NCI grade of diarrhoea
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Response rates based on patient assessment of diarrhoea
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Seroincidence of presumed typhoid infection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Vaccine seroefficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Greater adduction during deep-squat task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Greater internal rotation moment during deep-squat task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Lower transverse plane range of motion during deep-squat task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Oxygenation level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Saturation recovery time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BMD of the total body and lumbar spine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Energy consumption in prefrontal regions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prefrontal hemodynamic responses (oxygenated hemoglobin levels)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stroop test accuracy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Normal fatigue levels
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: condom use
Endpoint domain: Life impact
Endpoint subdomain: Sexual functioning
Primary endpoint: risky sexual behavior
Endpoint domain: Life impact
Endpoint subdomain: Sexual functioning
Primary endpoint: sputum conversion time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: self-efficacy in establishing achievable goals
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: self-efficacy around knowledge of community resources
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: new skills performed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Endogenous plasma levels of glucosamine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Glucosamine elimination half-life
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: work and social adjustment
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Cholesterol efflux (ChE) from macrophages
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: fixation failures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: average yield loads
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: self-rated confidence communicating with people with aphasia
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: proficiency at engaging in an everyday conversation
Endpoint domain: Life impact
Endpoint subdomain: Communication functioning
Primary endpoint: proficiency obtaining a case history
Endpoint domain: Life impact
Endpoint subdomain: Communication functioning
Primary endpoint: Akt phosphorylation responses to insulin
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: adipocyte lipolysis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Average periimplant bone loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: teenage births
Endpoint domain: Mortality/survival
Primary endpoint: Diagnostic accuracy of MSCT
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: pain index at postoperative day 4
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Knowledge on breast cancer
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Knowledge on breast self examination
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Frequency of BSE practice
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: WI and HAI scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma levels of adrenaline
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: DNS and DNE scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: NPQ score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MPQ score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Frequency of oncogene mutations (PIK3CA and KRAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: time to remedication
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Control of HRV shifts in a parasympathetic direction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: resistivity index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: rate of abnormal placental attachment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Improvement in balance (BBS score)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Absenteeism rates
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Presenteeism rates
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Negative critical work incidents
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Safety and tolerability of pomegranate juice and extract
Endpoint domain: Adverse events/effects
Primary endpoint: Cystoid macular edema
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Percentage of prescribed medication taken
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Functional disability criteria met
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak exercise cardiac output
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: total BMD increase
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Maximum willingness to pay
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: FVIII half-life
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: weight-adjusted clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: in vivo recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Improvements in static balance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvements in dynamic balance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Surgical conditions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Pregnancy salvage rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Resistivity index (RI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Pulsatility index (PI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Functional Independence Measure (FIM)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Functional scores (DASH)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: complete clinical cure rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: tolerability score
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of undesirable effects
Endpoint domain: Adverse events/effects
Primary endpoint: clearance rate of penile warts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Ultrasonographic imaging findings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinical improvements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Electrophysiological improvements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in PASS scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in BBS scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: plasma NOx levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median time to onset of analgesia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean total pain relief score over 8 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient response rate on patient global assessment of response to therapy at 24 hours
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Inflammatory and endothelial responses
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Moderate to severe diarrheal purge
Endpoint domain: Adverse events/effects
Primary endpoint: SMA blood flow volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Sexual activity
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: in-hospital deaths
Endpoint domain: Mortality/survival
Primary endpoint: neutrophil recovery >500/mm3
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: ED50 of phenylephrine infusion rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Total consumption of phenylephrine until delivery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 1-year incidence of diabetes
Endpoint domain: Mortality/survival
Primary endpoint: Average walking speed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: O2peak values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: daytime systolic BP of less than 130 mmHg
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Sensitivity of serial tryptase measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Specificity of serial tryptase measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Satisfactory outcome according to Flynn's criteria
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: duration of medication
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: number of sequelae
Endpoint domain: Adverse events/effects
Primary endpoint: Mean post-PCI hospital stay
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Mean cumulative medical cost per outpatient
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Quality adjusted life years
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: ADL motor and ADL process skills improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in CON 1RM
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Area of muscle injury
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Improvement of inflammatory acne lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Numeric Rating Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: success rate (graft taking)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Epworth Sleepiness Scale (ESS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: rate of disability progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: annual relapse rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increase in plasma volume (PV) at rest
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maintenance of plasma volume (PV) during exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Decrease in total cholesterol (TC)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Decrease in low-density lipoprotein (LDL-c)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Decrease in right carotid intima-media thickness (cIMT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: NIH obstruction percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: MACE rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: rate of cognitive decline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Recording quality of food records
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement of evaluation parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tolerability of phytothermotherapy
Endpoint domain: Adverse events/effects
Primary endpoint: Death during follow-up
Endpoint domain: Mortality/survival
Primary endpoint: Confirmed DVT
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Venous thromboembolism (VTE)
Endpoint domain: Adverse events/effects
Primary endpoint: Improvement in somnolence (ESS)
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Improvement in depressive symptoms (BDI)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: mean percent changes in lumbar spine BMD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean duration of grade 4 neutropenia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Prevalence of unprotected intercourse
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Median interval to wound healing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum IGFBP-3 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change in FACT-H&N score from baseline to 6 months
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: percentage of patients with complete biomarker status able to start adjuvant treatment within 2 months of surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sitting balance improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mortality rates at 3 months
Endpoint domain: Mortality/survival
Primary endpoint: Onset time for femoral nerve block
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: partial remissions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: CA125 levels decrease
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Upper extremity muscle strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: plasma high-sensitivity C-reactive protein levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: monocyte release of TNF-alpha, IL-1beta, IL-6, and monocyte chemoattractant protein-1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: lipid/lipoprotein profile improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Total sedation time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: OSBD‐r scores during manipulation
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Occurrence of desaturation
Endpoint domain: Adverse events/effects
Primary endpoint: errors of the spatial working memory task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Cocaine-induced heart rate elevations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Cocaine craving levels
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in fasting plasma glucose levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in glycosylated haemoglobin levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: mean visual analog scale scores (at rest) at 6 hours after surgery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proven infection rate
Endpoint domain: Adverse events/effects
Primary endpoint: Suspected infection rate
Endpoint domain: Adverse events/effects
Primary endpoint: Duration of time to suspected infection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Incidence of phlebitis
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of catheter-related infection
Endpoint domain: Adverse events/effects
Primary endpoint: Response rate to mailed survey
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Decrement in blood biomarkers implicated in coagulation activation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Improvement in fibrinolytic activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Thromboembolic events reported
Endpoint domain: Adverse events/effects
Primary endpoint: Vz/Fnorm
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hair clearance percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Blood culture-positive fever
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Change in mean 24-h systolic BP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of new-onset hypertension
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Fewer urgent visits to the GP for exacerbations
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Fewer scheduled visits to the GP
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Reduced work absenteeism
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Epidural fentanyl requirement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Wound healing grade
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Incidence of dermatitis
Endpoint domain: Adverse events/effects
Primary endpoint: plaque pH measurements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in overall NEI-VFQ score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: total cardiac mortality
Endpoint domain: Mortality/survival
Primary endpoint: Percentage of patients reaching target IOP (≤18 mmHg)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient preference for TTFC over prior therapy
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life