TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Jaeger notation near uncorrected visual acuity change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of prostate cancer diagnoses
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Percentage of Participants Who Experienced a More Than 50% Reduction in Expired Carbon Monoxide (CO) Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Average Pittsburgh Sleep Quality Inventory (PSQI) Score
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Change in Distance Walked (Meters) on the 6-minute Walk Test (6MWT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in isokinetic knee extension and flexion peak torque
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in handgrip strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Peak Vertical Ground Reaction Forces (vGRF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Degree of helpfulness of the symptom management manual
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of accepted liver registrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: reduction in maximum symptom days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of spontaneous sinus rhythm recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: MNA-SF score for undernutrition screening
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Time to first opioid
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety and tolerability of carbon monoxide
Endpoint domain: Adverse events/effects
Primary endpoint: Mean Fractional Anisotropy in C5 to C8 nerve roots
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Number of Patients With Wound Complications
Endpoint domain: Adverse events/effects
Primary endpoint: Re-operation Rates
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Complete Molecular Response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Upper extremity circumference
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Emotional Eating - 2-weeks Post-intervention
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Emotional Eating - 3-months Post-Intervention
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Total antioxidant activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Decrement (elasticity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in Frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: end-tidal carbon dioxide (ETCO2)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Serum level of Brain derived neurotrophic factor
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Number of Days Survived Without a Fall
Endpoint domain: Mortality/survival
Primary endpoint: Area under the ROC curve of the Soluble Fibrin for the diagnosis of PE
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: postoperative prevalence of stress incontinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Incidence of heart attacks
Endpoint domain: Mortality/survival
Primary endpoint: Decision making abilities
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of intrusion of the traumatic memory
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: VDJ and VJ segment comparison in immunoglobulin chains
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Mutational diversity following vaccine-induced affinity maturation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Objective Response (OR) (Partial Responses + Complete Responses)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Maximum Tolerated Dose (MTD) of Short Infusion LMB-100 + Nab Paclitaxel
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Tolerated Dose (MTD) of Continuous Infusion LMB-100
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of participants with HoFH due to LDLR mutations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevention of first episode of hepatic encephalopathy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Successful drainage of abscess
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Change in Expiratory Flow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Dietary Sodium Restriction Questionnaire (DSRQ) score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: DC-STAMP expression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Disease severity in PsA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Treatment response in PsA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Receiving bDMARDs in Monotherapy
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Number of Patients With Nausea and Emesis
Endpoint domain: Adverse events/effects
Primary endpoint: Number Receiving Rescue Antiemetics
Endpoint domain: Adverse events/effects
Primary endpoint: Concentration of sufentanil in human breast milk
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Volume of human breast milk
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Dose of sufentanil in human breast milk
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual perception and cognition
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in Hemodynamic Parameters of Radial/Ulnar Artery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes in Hemodynamic Parameters of Brachial Artery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes in Cross-sectional Area of Radial/Ulnar Artery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Painfree walking distance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mass balance recovery of total radioactivity (Ae) in urine, faeces and expired air
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak Plasma Concentration (Cmax), pitolisant and major metabolites
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the plasma concentration versus time curve [AUC(0-tau), AUC(0-inf), %AUCextrap], pitolisant and major metabolites
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of hOGTT venous plasma equivalent glucose results within ±10% of paired venous plasma glucose
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Response probability (confirmed complete and partial response)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Severity of envenomation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain, VAS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of consultancies for sexually transmitted diseases
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Rivermead Behavioral Memory Test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Everyday Cognition Scale
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Older Peoples Quality of Life Questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: %CD4 Expressing CCR5 HIV Co-receptor in the Cervix and Endometrium
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Intervention offer by practitioner
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in muscle tone of biceps brachii and rectus femoris
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Change in maximal extension of elbow and knee
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Distance walked in six minute walking test (6MWT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent of Blood Glucose Results Within +/-15mg/dL or +/-20%
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Craving as Assessed by the Brief Substance Craving Scale (BSCS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Craving as Assessed by the Obsessive Compulsive Drug Use Scale (OCDUS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cue Reactivity as Assessed by a Visual Analogue Scale (VAS) of Cocaine Craving
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Brain White Matter (WM) Integrity as Assessed by Diffusion Tensor Imaging (DTI) Fractional Anisotropy (FA) Value (Region - Posterior Thalamic Radiation)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Incidence of dementia diagnosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Incidence of Minimal Cognitive Impairment (MCI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Area Under Plasma Concentration-time Curve (AUC0-t)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Plasma Concentration-Time Curve (AUC0-inf)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of patients with a score of 0 for cells in the anterior chamber
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of patients with no clinically evidenced bacterial infection
Endpoint domain: Adverse events/effects
Primary endpoint: Ham-D (Hamilton Depression Rating Scale for Depression) 17-item
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Clinical Global Impression - Severity Scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Quality of Life, Enjoyment and Satisfaction Questionnaire (Q-LES-Q)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Area under the curve (AUC) of cutaneous blood flow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: 20-meter walk test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: isokinetic muscle performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: duration of cerebral desaturation events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Positive conversion rate of MuV hemagglutination inhibition antibody
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Positive conversion rate of MuV neutralization antibody
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Protective effect of the MuV vaccine in preventing mumps
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Paranoid Thinking
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Psychotic Symptoms
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Participant Acceptability
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in CTS symptom severity score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Correlation of pre-treatment strain with post-treatment changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient satisfaction of rehabilitation method
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Peripheral arterial tone
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of Participants Who Achieved Morphologic CR
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: neurosensory disturbance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Diastolic echocardiographic changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Participation and refusal rate of Dignity Therapy
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Overall satisfaction of patients and their relatives
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Number of exacerbation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Breath Delta Value
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Vital signs (body temperature)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Vital signs (heart rate/pulse)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Subject in Agreement (Bigger Eyes)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of Subject in Agreement (Defines Eyes)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of Subject in Agreement (Enhance Eyes)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in resilience levels
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: unsafe sex self-report survey item
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Abnormal Involuntary Movement Scale (AIMS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Change in Wisconsin Card Sorting Test (WCST)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Change in Continuous Performance Test (CPT)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: NEST Scale Total Score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of participants experiencing an AE/SAE
Endpoint domain: Adverse events/effects
Primary endpoint: 48 Hour Post-surgical Opioid Use
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Number of participants with PCO
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in anxiety-Hospital Anxiety and Depression Scale (HADS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in depression-Hospital Anxiety and Depression Scale (HADS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in post-traumatic stress measured by the PTSD Checklist for DSM-5 (PCL-5)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in health-related quality of life measured by Medical Outcomes Study 12-item Short-Form General Health Survey (SF-12)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change in Mental Health Self-Efficacy Scale (MHSES) score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: hemoglobin increase after therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Time of Elimination of Phenytoin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Accuracy of the assignment of bleed vs. non-bleed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Accuracy of patient reported bleeding compared to HHUS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 60-day ≥Grade 3 Pancreatic Complication Rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Quality of mesorectal excision
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: 1-hour Platelet Reactivity Unit (PRU)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in capacity to conduct Root Cause Analysis
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Improvement in capacity to lead patient safety ISO certification review
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Mean of Serum Low-density Lipoprotein Cholesterol (LDL-C)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Bone mineral mass
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bone strength-strain index
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants with Dose-Limiting Toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Maximum Tolerated Dose (MTD) of DCDS0780A
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Recommended Phase 2 Dose (RP2D) of DCDS0780A
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of intrinsic ventricular events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of grade 2-4 diarrhea
Endpoint domain: Adverse events/effects
Primary endpoint: Risk of developing small bowel neoplasia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Proportion of women who die
Endpoint domain: Mortality/survival
Primary endpoint: Proportion of women who undergo hysterectomy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Number of Participants Who Experienced Clinical or Laboratory Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Feasibility of emobilize application
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Acceptability of emobilize application
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Alzheimer's Disease Assessment Scale-cognitive Subscale (ADAS-cog)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Number of Participants With a Significant Increase in Perfusion Defects
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Tooth Movement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Subjects With Mixed Chimerism
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent of Eyes Experiencing at Least 1 Grade Reduction in LWE
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline in CDRS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall coparenting quality
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Quality of coparenting around infant sleep contexts
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Quality of infant sleep
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Incidence of varicose veins
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Incidence of superficial thrombophlebitis and DVT
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Control of center of pressure (COP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AEs (spontaneous and solicited)
Endpoint domain: Adverse events/effects
Primary endpoint: Pharmacokinetic parameters (AUClast, Cmax, Tmax)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Voriconazole concentration in serum
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to complete reduction of the fracture
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Percentage of Participants Achieving EASI75
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Glasgow Outcome Scale Extended (GOSE) score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Locoregional Recurrence Rates
Endpoint domain: Mortality/survival
Primary endpoint: Distant Failure Rate
Endpoint domain: Mortality/survival
Primary endpoint: Rate of Major Pathologic Treatment Effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Graft re-rupture
Endpoint domain: Adverse events/effects
Primary endpoint: Learning Effectiveness
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning