TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Number of subjects with abnormal blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of subjects with abnormal heart rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of subjects with abnormal 12-lead ECG assessment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of subjects with abnormal findings on lead II cardiac monitoring
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: incidence, severity of adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: incidence, severity and duration of intraoral pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: clinically significant changes in vital signs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total Volumetric Wear
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Liver inflammation and fibrosis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Liver and biliary outcomes
Primary endpoint: Percentage of Participants Achieving Virologic Response (HBV DNA < 20 IU/mL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Percentage of Participants Who Experienced Graded Treatment-Emergent Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants Who Experienced Graded Treatment-Emergent Laboratory Abnormalities
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of major adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Reported Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of Infections post-infusion
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Self-reported Ability to Participate in Community Activities
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Acute salt sensitivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 129I kinetics
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in VAS score of spontaneous pain intensity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in VAS score of dynamic mechanical allodynia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in the medication satisfaction questionnaire (MSQ) score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of Participants With Solicited Local (Injection Site) Adverse Events (AEs) for 7 Days After Vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With Solicited Systemic Adverse Events (AEs) for 7 Days After Vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With Unsolicited Adverse Events (AEs) for 28 Days After Vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: Chest compression parameter
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Subjective effects scores for Urge to Smoke (UTS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Maximum change in pulse rate relative to baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Incidence of postoperative residual curarization
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neuromuscular outcomes
Primary endpoint: Change in serum lipid peroxide levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in levels of serum carotenoid
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Pre-therapy/Pre-procedure Stress Level Measured by Blood Pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Pre-therapy/Pre-procedure Stress Level Measured by Pulse
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Pre-therapy/Pre-procedure Stress Level Measured by Respiratory Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Pre-therapy/Pre-procedure Anxiety Level
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Level of thrombospondin (TSP1) and pigment epithelium derived factor (PEDF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Local tendon tissue displacement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Geometric mean AUCt
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in spherical equivalent refractive (RSE)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Resumption of oral feeding
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of penetration and aspiration
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of MRD negativity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Self-Reported Physical Activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: differences in Quality of Life from AQLQ(S)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: differences in FEV1 and FVC from spirometry
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: gastric levels of total antioxidant capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: gastric lipid peroxide levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: EMG Latency between intercostal muscles contraction and perineal muscles contraction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Individuals Diagnosed With Antisocial Personality Disorder
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hours/week spent in Moderate to Vigorous Physical Activity (MVPA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Satisfaction of patients and family members
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Acute renal injury
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Transport of exudate from wound bed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sustained and selective aspects of visual attention
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Visual memory function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Left ventricle longitudinal function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Functional reserve during rest and/or after exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of Participants With Unsafe Swallowing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Amount of Residue in the Pharynx
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duration of the Time Interval Between the Bolus Entering the Pharynx and Onset of the Pharyngeal Swallow (Swallow Reaction Time)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Relief of IBS symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Number of Participants With Residue of Concern
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum Anterior Isometric Tongue Pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Regular Effort Saliva Swallow Tongue Pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Unsafe Swallows
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Probability of persistent undetectable molecular residual disease (UMRD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Incidence of catheter-related infectious complications
Endpoint domain: Adverse events/effects
Primary endpoint: Time between catheter insertion and catheter failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Desaturation during ERCP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Mean of the individually heart rate corrected QT interval (QTcI) values
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Mean Urinary Free Cortisol (mUFC) ≤ 1.0xULN
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Percentage of Participants Without Treatment Failure During 2-Years of Observation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in metabolic indicators
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Improvement in fitness measures
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean change of ISNCSCI Motor Scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Ocular tensional fluctuation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in mean daily pain rating
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Change from baseline E/E' on echocardiography at 12 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Composite of death, myocardial infarction, cerebrovascular event, need of intervention on renal arteries and renal function impairment
Endpoint domain: Adverse events/effects
Primary endpoint: Regression of diabetic retinopathy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: number of patients cured
Endpoint domain: Mortality/survival
Primary endpoint: Heart-rate corrected QT (QTc) interval
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Proportion of patients with HIV RNA < 400 copies/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of patients with HIV RNA < 50 copies/mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Hemoglobin A1c Value (%)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Humoral immune response in terms of vaccine-homologous hemagglutination inhibition (HI) antibody titers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change from Baseline in Stress Scores at 8 Weeks
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Symptoms improvement at follow-up
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improved dietary quality
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Transition Dyspnoea Index (TDI) score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Area Under the Curve (AUC) 0-30min in FEV1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: postoperative residual discrepancy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Skin and Soft Tissue Infection (SSTI)
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of Methicillin-resistant Staphylococcus Aureus (MRSA)-Associated SSTI
Endpoint domain: Adverse events/effects
Primary endpoint: size of PDA
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Alcohol Use
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Tobacco Use
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Safety of the TCR-T treatment
Endpoint domain: Adverse events/effects
Primary endpoint: Successful return to sinus rhythm
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: sensitivity and specificity of ICG-based fluorescence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Proportion of subjects reaching iPTH target at 20th week
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Proportion of subjects reaching iPTH target at 32nd week
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Pituitary uptake of Ga-68-NODAGA-exendin
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Hearing Handicap Inventory for the Elderly/Adults (HHIE/A)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Bridging stent patency at 12 months
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Absence of procedure related complications and bridging stent related endoleaks at 12 months
Endpoint domain: Adverse events/effects
Primary endpoint: Neonatal Respiratory Failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Percentage of Days Transmitted
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in Intentions to engage in safer sex behavior at 6 months
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Intentions to engage in safer sex behavior at 1 year
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Proportion of Patients in Disease Remission at Six Months
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Achieving Clinical Remission at Week 24
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of Participants Achieving Endoscopic Remission
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Modification of nutritional status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: lower back pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: EEG and fMRI concordance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Colon Cleansing Procedure (ITT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Colon Cleansing Procedure (PP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Median Number of UUI Episodes Per Day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in total lipid content in the liver
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Visibility of Rotation Mark
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: change in abdominal leak point pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Multiple Sleep Latency Test (MSLT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Sleep
Primary endpoint: Psychomotor Vigilance Task (PVT)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Postexposure chemoprophylaxis efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Oseltamivir safety
Endpoint domain: Adverse events/effects
Primary endpoint: Postexposure chemoprophylaxis costs
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Change in Dim Light Melatonin Onset
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Number of Patients Who Relapsed
Endpoint domain: Adverse events/effects
Primary endpoint: Decrease of interleukin-4/interferon gamma index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Imatinib area under the curve
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Numeric rated scale
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Ultrafiltered volume during a study session
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Major pathologic response (MPR) rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: disability change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: gait speed change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Amount of Study Drug Required to Achieve Initial Hemodynamic Stabilization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: North Star Assessment for dysferlinopathy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Early Speech Perception Four Choice Spondee and Monosyllable
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Phonetically Balanced-Kindergarten
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cardiovascular mortality or non-fatal ACS
Endpoint domain: Mortality/survival
Primary endpoint: Womac Pain Score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Adalimumab failure at Week 24
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Laryngostroboscopic exam results
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of peripheral vascular resistance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Changes in blood lipid levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in pain ratings after blanket use
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Delis-Kaplan Executive Function System (D-KEFS) Stroop Inhibition-Switching Task
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cognitive functioning
Primary endpoint: Radiologic evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in fat z-score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement of psoriasis area and severity index scores (PASI scores)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall evaluation of the researchers (Physician Global Assessment, PGA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Symptom score reduce index (SSRI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Usability of the MKit WebApp
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Acceptability of the MKit WebApp
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Operative Forearm Bone Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total Body Bone Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Elbow Flexion Strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Forearm Supination Strength
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: MOTOR ASSESSMENT SCALE (MAS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: WOLF MOTOR FUNCTION TEST (WMFT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: FUGL- MEYER ASSESSMENT TEST
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PADSS score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in tinnitus loudness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Clinical status of tinnitus
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Proportion of patients who prematurely discontinued the study due to adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of patients without hepatic encephalopathy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Reproducibility of [F18]HX4 PET Imaging
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Exacerbations reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Delta IGF-I SDS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Changes in fibroid-related symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in cigarette smoking behaviors
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent change in flow-mediated vasodilation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in heart rate variability indices
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Percent change in carotid intimal media thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Corneal Aberration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: % change in LDL-C from baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes