TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: skeletal muscle blood flow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change in therapy due to monitoring
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: 1-year implant failure rates
Endpoint domain: Mortality/survival
Primary endpoint: 1-year patient failure rates
Endpoint domain: Mortality/survival
Primary endpoint: proportion of recurrences
Endpoint domain: Mortality/survival
Primary endpoint: Physician attendance at training
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Perceived preparedness to counsel smokers
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Office-based tobacco control activities
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PCL-M ratings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual analog scale score for pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: superior resolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: workload ratings
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: allogeneic red cell transfusion rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: proportion of patients requiring fresh frozen plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Positive vasovagal response
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: VAS reductions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: EQ-5D improvement
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: ODI score decrease
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Level of depressive symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CSF protein carbonyl concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Asthmatic attacks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PEF values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of hematuria of any grade
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Moderate or severe discomfort or bladder spasms
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of urinary tract infections (UTIs)
Endpoint domain: Adverse events/effects
Primary endpoint: Disease Activity Score of 28 joints (DAS‐28)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum high‐sensitivity C‐reactive protein (hs‐CRP) concentrations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: forehead cortex blood flow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Risk activities for transmission of zoonotic tuberculosis
Endpoint domain: Adverse events/effects
Primary endpoint: Knowledge about tuberculosis
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: 12‐Item Short‐Form Health Survey mental component scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Chance-corrected agreement (kappa)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improvement in Chinese medical clinical symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: partial pressure arterial oxygen/inspiratory fraction of oxygen (P/F) ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: lung compliance (Cdyn)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: 6-minute walking speed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Human Activity Profile
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SF-36 Physical Component summary score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Eight-hour mean plasma glucose levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Changes in students' knowledge about problems associated with under age drinking
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increases in parent‐child communication about alcohol use
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Students' alcohol use rates
Endpoint domain: Adverse events/effects
Primary endpoint: ATRS score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Retention at 6-month postpartum
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Early infant testing at 4-6 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: initial virological failure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: initial virological failure with antiretroviral resistance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Resolution of gross hematuria
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: early motor development
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative endothelial cell loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Corneal pachymetry
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean ISQ value
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: primary events
Endpoint domain: Mortality/survival
Primary endpoint: Wheelchair Skills Test score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Provocative dose of methacholine causing a 20% fall in FEV(1)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Mean trough plasma theophylline concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Symptoms of hypoglycemia
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Acceptance and value of PGx testing
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: DAS28 (CRP) <2.6
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Repeat PSA test or prostate biopsy
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Occurrence of NEC stage ≥ 2
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Correct classification of very severe disease in newborns
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Esophagitis improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Reflux index improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Reduction in inflammatory lesion counts
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Skin irritation tolerance
Endpoint domain: Adverse events/effects
Primary endpoint: mRNA expression of MUC4, MUC13, and MUC15
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement on the LSAS
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Requirement for intubation within 72 hours
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: prolongation of pregnancy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Retention of abstinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: visits to general practice or hospital
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: dose of beclomethasone dipropionate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maternal self-efficacy regarding influenza vaccine use
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Incidence rate ratio of leprosy
Endpoint domain: Mortality/survival
Primary endpoint: Reaching the therapeutic goal
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: 2h postprandial plasma glucose
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: plasma triglyceride
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Mean decimal BCVA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 4-week prolonged abstinence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Thrombin generation (prothrombin F1+2)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Fibrinolytic potential
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Keratocyte densities in the anterior and posterior stromal flap and anterior retroablation layer
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: alpha(1,2)fucosyltransferase activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MDRO-infections per 1000 inpatient days
Endpoint domain: Adverse events/effects
Primary endpoint: Area under the curve (AUC) from time 0 to time of last measurable plasma concentration (AUC0‐t)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under the curve (AUC) from time 0 to infinity (AUC0‐inf)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Plasma concentration at 12 h (C12 h)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Laugh index
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: DGH level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sustained smoking reduction rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: perceived confidence in using the food label
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Voice onset time of the consonant [d]
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Body Mass Index (BMI) SDS reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of children classified as grossly overweight
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: VE/VCO(2) slope
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: optimal time to commence dialysis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Cure rate at D11
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Recovery confirmation at D25
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: diabetes risk
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Incidence of postoperative atrial fibrillation
Endpoint domain: Mortality/survival
Primary endpoint: Knee injury and Osteoarthritis Outcome Score (KOOS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: clinical pain relief
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: RRI response to skin incision
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Levels of agreement of MDT members
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Decision sharing
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Consensus
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Confidence in the decision
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Severity of inflammation of the palate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of glossitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Colonization of the oral mucosa by Candida
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: VAS for total pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Recovery of the hemiparetic upper limb
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: normalisation of slow wave activity in the EEG
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: mobility of implants compared to natural teeth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: stability assessment using Periotest
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: changes in PTVs for implant-bone complex evaluation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 24 months LFS
Endpoint domain: Mortality/survival
Primary endpoint: 24 months overall survival (OS)
Endpoint domain: Mortality/survival
Primary endpoint: Mean difference in Na excretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Occurrence of headaches
Endpoint domain: Adverse events/effects
Primary endpoint: 28-day headache rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fat weight loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Undetectable viral load
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Adherence to antiretroviral therapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: rate of new nonmelanoma skin cancers
Endpoint domain: Mortality/survival
Primary endpoint: rate of new basal-cell carcinomas
Endpoint domain: Mortality/survival
Primary endpoint: rate of new squamous-cell carcinomas
Endpoint domain: Mortality/survival
Primary endpoint: number of actinic keratoses
Endpoint domain: Mortality/survival
Primary endpoint: Attractiveness of smokers
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Pregnancy prevention
Endpoint domain: Mortality/survival
Primary endpoint: secretion clearance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adverse events (hematomas, seromas, wound infections, etc.)
Endpoint domain: Adverse events/effects
Primary endpoint: Mean scores of Hong Kong index of dyspepsia severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Rate of H. pylori infection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: % PEF (Peak Expiratory Flow)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: complete chest wall recoil
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Changes in muscle VAS at 8 and 16 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Physician global VAS at 16 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: HAM-D(6) score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Development of anti-infliximab antibodies
Endpoint domain: Adverse events/effects
Primary endpoint: Trough serum infliximab levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in MGI scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in BI scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean SHIM score improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient satisfaction (EDITS score)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: GCF MMP-8 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean PD scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean GI scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: average total number of ampoules of hMG
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: length of administration of hMG
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: time interval between GnRHa initiation to oocyte retrieval
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Improvement of clinical signs and symptoms of rosacea
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Reduction of skin reactivity to trigger factors
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: nocturnal urine output
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: number of nocturia episodes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Sensitivity of xMAP technology
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Specificity of xMAP technology
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Kappa value for consistency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum level of Tpo
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: RPC
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: RP%
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Hourly intraoperative blood loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Total fat reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Saturated fat reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Intraoperative blood loss >1,000 mL
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median liver transection time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Postoperative bile leakage
Endpoint domain: Adverse events/effects
Primary endpoint: QTcI change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Higher alcohol consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Cumulative NIPS score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Remission rates (Hamilton depression scale score <8)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Deepening of anterior chamber depth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of pregnancy-associated hypertension
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Adverse perinatal outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: self-perceived fatigue
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: colorectal cancer incidence
Endpoint domain: Mortality/survival
Primary endpoint: Serum ß2‐m levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Expression of leptin genes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Expression profiles of transcripts as biomarkers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: All-cause 12-month mortality
Endpoint domain: Mortality/survival
Primary endpoint: reductions in AS and interpretation biases
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increase in hair counts
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of responders to BoNT‐A
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Yale‐Brown Obsessive Compulsive Scale (YBOCS) scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Bioavailability of trovafloxacin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum serum concentration (Cmax) of trovafloxacin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to Cmax of trovafloxacin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Decrease in back pain-related disability
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Total quality-of-life scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Recurrent bleeding
Endpoint domain: Adverse events/effects
Primary endpoint: Disease activity flare
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Clinical variables of arthritis activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: weight and shape concern
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: general self-esteem
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing