TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Time from balloon insertion to delivery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage change in blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: overall dyspeptic symptom intensity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: risk of severe visual loss
Endpoint domain: Mortality/survival
Primary endpoint: change in size of neovascular membranes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: risk of elevated intraocular pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ocular outcomes
Primary endpoint: Change in cardiac output (L/min)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Mean score of physical activity
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Total iodine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Iodine injection rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proliferation index of γδ‐T cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Symptoms of illness
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: temporal and spatial gait performance parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of referrals to smoking cessation services
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: PCEA bolus requirements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Willingness to undergo HPV self-testing
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Likelihood to attend follow-up after positive HPV test
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: PCDR normalization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: wound-related complications and mortality
Endpoint domain: Adverse events/effects
Primary endpoint: Disease-Free Survival (DFS) at 10 years
Endpoint domain: Mortality/survival
Primary endpoint: Overall Survival (OS) at 10 years
Endpoint domain: Mortality/survival
Primary endpoint: Percentage weight loss (%WL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Worst joint pain scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Lower transfusions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Shortened hospitalization
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Improved diastolic function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: conductance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: bicycle helmet use
Endpoint domain: Life impact
Endpoint subdomain: null
Primary endpoint: eto2 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: plaque index score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Oral health outcomes
Primary endpoint: average mucositis score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in facial skin complaints
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: stereopsis level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Thermal sensation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MIBG defect size
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Percentage of subjects who were louse-free one day after treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Improvement in proprioception
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-reported functional difficulty
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Postoperative troponin T levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: recovery index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Prevalence of suboptimal plasma levels of vitamins E, B12, and C
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: catheter-related septicemia
Endpoint domain: Adverse events/effects
Primary endpoint: HiSCR achievement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: HS-PGA Response achievement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: duration to first occurrence
Endpoint domain: Mortality/survival
Primary endpoint: likelihood of addressing or focusing on a topic
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: cumulative problem alerts
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Adverse effects of aspirin therapy
Endpoint domain: Adverse events/effects
Primary endpoint: Saturation of oxygen in arterial blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: pH of arterial blood
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Percentage of patients showing > 50% reduction in VAS pain score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of patients not requiring analgesic drugs
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean post-procedural VAS pain score reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean static pain score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Glucose improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Antisteatogenic effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Correctly identified problem drinkers
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Referral behaviour of physicians
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sum score of key and other signs and symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: duration of physical exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: total workload during ergometric test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Increase in diagnostic yield of GPA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: LEP N2-P2 PtP amplitude
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AMS score improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: BFR to vascular occlusion and local heat
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Free radicals
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Arrhythmia episodes
Endpoint domain: Adverse events/effects
Primary endpoint: Glucose profiles
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Mean left ventricular wall thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: N-terminal prohormone of brain natriuretic peptide
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: number of viable airborne bacteria
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: 2-year progression-free survival (PFS) rate
Endpoint domain: Mortality/survival
Primary endpoint: Achievement of European LDL-C goals
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Volume of pericardial effusion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of postoperative atrial fibrillation
Endpoint domain: Adverse events/effects
Primary endpoint: All recorded S&R injuries
Endpoint domain: Adverse events/effects
Primary endpoint: Medically treated S&R injuries
Endpoint domain: Adverse events/effects
Primary endpoint: Need for local anaesthetic supplementation
Endpoint domain: Adverse events/effects
Primary endpoint: Volume of supplemental local anaesthetic
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Need for additional sedation or analgesia
Endpoint domain: Adverse events/effects
Primary endpoint: rectal temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: ASSIST scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: adherence to moodManager
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: predicted effect-site propofol concentrations for adequate anesthesia
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Endoscopic findings
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Nucleoside analogue mutations (NAM)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Q151M complex
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: M184V mutations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CHADS2 scores ≥1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Reactive hyperaemia index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: maximal endothelium‐dependent vasodilatation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Plasma concentrations of T4
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Major symptom complex score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total symptom complex score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean arterial sevoflurane concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean arterial desflurane concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fraction uptake of the volatile agents
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient perceived autonomy support
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improvement in diagnosis scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in management scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Detection of melanoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Duration of numbness of soft tissues
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lexical ability performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: bleeding or incomplete abortion requiring hospital stay
Endpoint domain: Adverse events/effects
Primary endpoint: sustained biochemical response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: virologic end-of-treatment response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: average monthly health expenditures
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Cumulative survival rates on palatal/buccal surfaces
Endpoint domain: Mortality/survival
Primary endpoint: Changes in transcriptomic response of genes related to cardiovascular risk
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Voriconazole AUC(0-)(infinity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: progressive heart failure death
Endpoint domain: Mortality/survival
Primary endpoint: Overall compliance to treatment
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Quality of bowel preparation (BBPS score ≥7)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Ease of bowel prep regimen
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: OQ value
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of transparency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: serum triglycerides (TG)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: new palmitate levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Upper body strength improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Lower body flexibility improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Onset of Primary Open-Angle Glaucoma (POAG)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 1-year actuarial patient survival rate
Endpoint domain: Mortality/survival
Primary endpoint: 1-year actuarial kidney survival rate
Endpoint domain: Mortality/survival
Primary endpoint: 1-year actuarial pancreas survival rate
Endpoint domain: Mortality/survival
Primary endpoint: earlier detection of seizures
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Serum total or Derp-specific IgE levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: rate of fluid administration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Amount of beta-carotene required to form 1 microg retinol
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Low adherence to dapivirine ring
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Not returning the dapivirine ring
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Incidence of MACCE
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Creatinine kinase‐myocardial band (CK‐MB) isoform elevations
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Rate of POD (Postoperative Delirium)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of POCD (Postoperative Cognitive Dysfunction)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: baseline FHR
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: number of fetal movements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in PWD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of physically active patients meeting activity recommendations
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in MMSE
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Lack of decline of MMSE below 23
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Anti-IIa activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: visualization of cell morphology
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sample preservation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Inter-laboratory agreement of HPV testing
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: total effective dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: dose length product
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Six- and 12-month survival
Endpoint domain: Mortality/survival
Primary endpoint: Freedom from acute rejection
Endpoint domain: Physiological/clinical
Primary endpoint: Portal venous diameter
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Lower fasting and postprandial blood glucose
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Overall diabetes knowledge
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Hours exercised per week
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Test experience rating
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Uptake of glucose into the forearm muscle
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Fatty acid suppression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in (a-a)DO2
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in MAS scores for muscle groups
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: EQ‐5D index value
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: problems in mobility
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: problems in pain or discomfort
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Late toxicity (grade 2 or 3 xerostomia)
Endpoint domain: Adverse events/effects
Primary endpoint: Daily fat consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Postoperative IV morphine consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: nitroglycerine requirement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: number of attacks of headache
Endpoint domain: Adverse events/effects
Primary endpoint: Isolation of H. pylori from gastric aspirates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Proportion of children making any ARI visits
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Median number of ARI visits/child
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time and cost saving benefits
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Medical personnel dose
Endpoint domain: Physiological/clinical
Endpoint subdomain: Radiation exposure outcomes
Primary endpoint: Dose area product
Endpoint domain: Physiological/clinical
Endpoint subdomain: Radiation exposure outcomes
Primary endpoint: Women's perceptions of antenatal care
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improvement of nasal obstruction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative change in nasal volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of delayed ischemic neurological deficit
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Modified Rankin Scale score of 4, 5, or 6
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Risk of CRB
Endpoint domain: Adverse events/effects
Primary endpoint: Change in ulcer size
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intensity of delusions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: median combined final score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean time to completion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adverse reactions intervention
Endpoint domain: Adverse events/effects
Primary endpoint: Primary stability of implants
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: CD4(+) T‐cell and humoral immune responses
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Need for later mechanical ventilation (MV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Eradication rate of V-AC in CAM-susceptible H. pylori-infected patients
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Eradication rate of PPI-AC in CAM-susceptible H. pylori-infected patients
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Eradication rate of V-AC in CAM-resistant H. pylori-infected patients
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: overall work impairment
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: impairment in functioning due to FM
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: 6 minute-walk-distance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: St. George's Respiratory Questionnaire score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: serum concentrations of estrone
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes