TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Number of subjects with small‐intestinal mucosal injuries
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: median late rotation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: severe early rotation
Endpoint domain: Adverse events/effects
Primary endpoint: anticlockwise rotation occurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 30-day NACEs
Endpoint domain: Mortality/survival
Primary endpoint: BARC 2-5 type bleeding
Endpoint domain: Adverse events/effects
Primary endpoint: Pain on most days for at least a month
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intermittent pain in DIP and PIP joints
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean arterial pressure (MAP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Sensory taste preferences for milk and salty snack foods
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Adherence to adequate dosage of antidepressant medication for 90 days or more
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Quality of care rated as good to excellent
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: 50% or more improvement on the Symptom Checklist‐90 Depressive Symptom Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Remission at week 6
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rectal bleeding resolution
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: level of depressive symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: hemodynamic results
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: EPDS score >=12 at six months
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: percentage of time with pH <4
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: sleep fragmentation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Perceived Medication Benefit score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: juice consumption
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: fruit servings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: vegetable servings
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Common drug-related toxicities
Endpoint domain: Adverse events/effects
Primary endpoint: Sensitivity and specificity of the (13)C-EUBT
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in clinical parameters
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean cost saving
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Need for additional oral analgesics
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: physiologic distress
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: motor organization
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: self-regulatory ability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of neonatal hypocalcemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Increased gestational age at delivery
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improved neonatal weight
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Less admission to neonatal intensive care unit
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Cognitive and memory function improvements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Treatment efficacy for female pattern hair loss
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Endothelial dysfunction (ED) prevalence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Overall therapeutic effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: FIM gain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Returning home
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: elation
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: cumulative risk of rebleeding
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Incidence of recurrent adenoma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: incidence of PONV
Endpoint domain: Adverse events/effects
Primary endpoint: Decreased circulating levels of von Willebrand factor antigen
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Impairment of platelet function (closure time with collagen/epinephrine)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: painfree walking distance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ankle/arm index
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: frequency and severity of side effects
Endpoint domain: Adverse events/effects
Primary endpoint: lesion count reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: levels of anxiety and depression
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: frequency of probable mental disorder
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Locating colonic lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rates of PAEs
Endpoint domain: Adverse events/effects
Primary endpoint: Rates of musculoskeletal PAEs
Endpoint domain: Adverse events/effects
Primary endpoint: General cognitive index improvement
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Immediate recall domain improvement
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Hooper Visual Organization Test improvement
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Post-treatment erythema
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Post-treatment hyperpigmentation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Relief of depression
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Patient satisfaction with procedure
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Acceptability of repeat procedure
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Markers of mitochondrial biogenesis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Central retinal artery resistance index (CRA RI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Ocular blood flow amplitude (OBFa)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Axial length (AL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intravaginal ejaculatory latency time (IELT)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patients' subjective feelings of ejaculatory control
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Patients' sexual satisfaction
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: overall disease activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Expression levels of VLA-4 and LFA-1 on immune cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Serum levels of soluble VCAM-1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Volumes of T2-weighted plaques
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: acute myoPS response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: integrated myoPS increase
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Compliance with preventive measures
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Response criteria met
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: SDNN10
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: BRS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: maintenance of exercise capacity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: improved health‐related quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: eradication of baseline pathogens
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: time to pathogen eradication
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time lost for work/daily activities
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Days spent on hospital visits
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Convenience and satisfaction with treatment
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Incidence of abusive head injuries
Endpoint domain: Mortality/survival
Primary endpoint: Area under the plasma concentration-time curve (AUC) of tamoxifen
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak plasma concentration (Cmax) of tamoxifen
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Elimination half-life (t1/2) of tamoxifen
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: patient cost of hospitalization
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: curve correction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Severity of Alcohol Withdrawal Syndrome (AWS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duration of ICU treatment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: symptomatic and pathologic therapeutic effect
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: levels of gastric mucosal Zn, Cu, cAMP, SOD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: serum LPO levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Shortening of atrial effective refractory period (ERP)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Increased dispersion of refractoriness
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Degree of integration and normalisation of clinical data reports
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of early perineal wound complications
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Composite of death, myocardial infarction, emergency bypass, or target lesion revascularization
Endpoint domain: Mortality/survival
Primary endpoint: PIP (Peak Inspiratory Pressure)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: C (Compliance)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: PETCO2 (End-tidal CO2)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Desire to Eat
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: mean number of cardiac risk factors above target
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: patients with systolic blood pressure below target
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: sitting systolic/diastolic BP reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: decision preparedness
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: decision conflict
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Hunger score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: morbidity mainly due to heart failure and ischemic cerebrovascular events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Genomic similarity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Maximum accuracy of SNP selection
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: subjective knowledge
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: treatment preferences
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: pain-related quality of life
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Acid-related sensitization
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: category fluency performance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: smoke-free status
Endpoint domain: Mortality/survival
Primary endpoint: Heart rate during submaximal and peak exercise
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Ratio between low and high frequency spectral components of heart rate variability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: primary closure rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: short‐term neonatal outcomes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MACCE event rate
Endpoint domain: Mortality/survival
Primary endpoint: Increased early and late phase symptoms after allergen challenge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain at rest and upon movement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Recovery of nonassisted mobilization
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Increment in PaO2/FIO2 ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Decrease in venous admixture
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: 5-year major amputation rate
Endpoint domain: Mortality/survival
Primary endpoint: 5-year amputation-free survival
Endpoint domain: Mortality/survival
Primary endpoint: total body mass
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ventral striatal activity during anticipatory reward/loss processing
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Inflammatory giant-cell deposit formation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: intraoperative opioids requirements
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: M1-area under the curve (AUC(0-30h))
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: gingival blood flow recovery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: pocket depth reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: healing time of sore nipples
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Peak PRL responses
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in collagen I deposition in lymph node specimens
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in collagen I deposition in adipose tissue specimens
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in fibronectin deposition in adipose tissue
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time required for getting up
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time required for walking
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time required for re-establishment of gastrointestinal transit
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Burden
Endpoint domain: Life impact
Endpoint subdomain: Societal/carer burden
Primary endpoint: incidence and severity of toxic reactions
Endpoint domain: Adverse events/effects
Primary endpoint: rate of operation following neoadjuvant chemotherapy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Primary bloodstream infections (BSI)
Endpoint domain: Adverse events/effects
Primary endpoint: Tracheal lesions at time of extubation
Endpoint domain: Adverse events/effects
Primary endpoint: composite CV outcome
Endpoint domain: Mortality/survival
Primary endpoint: kidney outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Overall confidence
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in CGI-I score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient satisfaction with wound closure
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Time taken for application of tissue adhesive
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of normal resonance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of nonhypernasal outcome
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Success rate of Furlow double-Z palatoplasty
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tendon regeneration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tolerability of avagacestat
Endpoint domain: Adverse events/effects
Primary endpoint: pulsatile cortisol secretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: radical resectability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: lymph node metastasis rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: time-averaged pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Health-related Quality of Life (HrQoL)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Quality-adjusted life years at 10 years
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Cardiovascular readmission rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Quality of Recovery‐40 scores
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: MMA (Mean Aqueous Humor Outflow)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hand eczema severity index score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Dermatology life quality index score
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Sensitivity and specificity for myopic refractive error detection
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative endophthalmitis
Endpoint domain: Adverse events/effects
Primary endpoint: Final tHcy levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Dynamic pulmonary compliance
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Hormonal stress responses (e.g., plasma epinephrine, norepinephrine)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Cases of pneumonia
Endpoint domain: Adverse events/effects
Primary endpoint: Time to healing
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Duration of treatment in the ED
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Number of isoetharine treatments required
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: MM neutrophils reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Upper limb goal attainment
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Isometric knee extension peak torque
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: diastolic blood pressure values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: overall sexual functioning (total PISQ‐12 scores)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Risk of developing ACPA-positive RA
Endpoint domain: Mortality/survival