TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Incidence of Obstructive Sleep Apnea
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Sibling Prosocial Behavior
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Sibling Intimacy
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Sibling Relationship Inventory: Negativity Subscale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Sensitivity of AF detection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Specificity of AF detection
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Remifentanil TCI effect site concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-Operative Persistent Pain
Endpoint domain: Adverse events/effects
Primary endpoint: Maximal Plasma Concentration (Cmax) of AGN-223575
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 30d mortality rate
Endpoint domain: Mortality/survival
Primary endpoint: Composite of ISTH Major Bleeding/Clinically Relevant Non-major Bleeding
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants With a Decrease of ≥50% in Prostatic Specific Antigen (PSA)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Objective Response Rate (ORR) Based on RECIST 1.1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Patients with at least one severe adverse event
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of offers accepted
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Affective bias in decreasing condition
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Serum Escitalopram levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cerebral presynaptic density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Visual Analog Scale (VAS) Change From Baseline
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: PHQ-9 Completed Fidelity
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in Glycemic profiles
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Rate of rise in PSA
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to viral clearance (RT-PCR negativity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Change in Social Connectedness (SC)
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Change in Resting heart rate variability (HRV)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in HRV reactivity to stress induction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in HRV recovery from stress induction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: serum concentration of ANXA2
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: urinary concentration of ANXA2
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Free light chain removal
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Response Rate (ORR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in child morbidity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage Changes in Fibroblast Growth Factor-23 (FGF-23) Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Percentage Changes in Parathyroid Hormone (PTH) Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: reduction of neuropathic foot pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in Severity of Cold Symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cure (reduced pain, swelling and otorrhea)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline to Week 116 in Global Outcome
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: total amount of insulin required for glycemic control
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Recurrence of intimate partner violence
Endpoint domain: Adverse events/effects
Primary endpoint: Health-specific quality of life
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Harms of screening and/or usual care
Endpoint domain: Adverse events/effects
Primary endpoint: Efficacy of Dexamethasone for PONV
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 2-item nausea-score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Arm function as measured by the Box and Block test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Walking speed as measured by the 6 minutes walk test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Patient Health Questionnaire (PHQ-8)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Pregnancy rate (>12 weeks)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Spontaneous abortion rate
Endpoint domain: Adverse events/effects
Primary endpoint: Clinical success rate of pulpotomy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Radiographic success rate of pulpotomy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Annualized Qualifying Relapse Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Confirmed Objective Disease Response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Sjögren's syndrome disease activity index
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of intraepithelial neoplasia grade 3 or worse (CIN3+)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Percentage of Participants Who Experienced Treatment-Emergent Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants Who Experienced Treatment Emergent Serious Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Percentage of Participants Who Experienced Grade 3 or Higher Laboratory Abnormalities
Endpoint domain: Adverse events/effects
Primary endpoint: urinary spot albumin creatine excretion ratio (UACR) change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Number of Patients With Treatment Related GI and/or GU Toxicity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: SpO2 Percentage
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of anaemia (Haemoglobin<11 g/dL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Number of Angina Episodes Per Week
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Prolonged Abstinence from Smoking
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Acetabular wear
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pneumococcal vaccination rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Mean Percent Body Weight Change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: First Hospitalization for Cardiovascular Reason
Endpoint domain: Mortality/survival
Primary endpoint: Interference Control
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Change in GRID-HAMD17 Total Score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Number of Hemorrhage events
Endpoint domain: Adverse events/effects
Primary endpoint: Number of other AEs
Endpoint domain: Adverse events/effects
Primary endpoint: Cardiac index measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Connectivity as Measured by fMRI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Degree of corneal steepening
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PCL Overall Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Social continence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Proportion of items exchanged during counseling
Endpoint domain: Life impact
Endpoint subdomain: Delivery of care
Primary endpoint: Time to Mycobacterium tuberculosis sputum culture conversion to negative
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Change in the total AUDIT-C score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of emergency department visits
Endpoint domain: Resource use
Endpoint subdomain: Hospital
Primary endpoint: Change of peripheral blood pressure
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Changes in eicosanoids/metabolites including PGE2, PGE3
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cytologic results of the cervico-uterine smear
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Histologic results of the cervical biopsies
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Extent of dysplastic lesions
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Local disease recurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Number of patients with skeletal involvement assessed by PET/MR
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: risk of perinatal transmission of HIV
Endpoint domain: Mortality/survival
Primary endpoint: rate of HIV disease progression
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change From Baseline in Knee Pain as Assessed by Average of Daily Pain Numeric Rating Scale at Week 8
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean Change in Haemoglobin Concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Disease-specific metabolic/microbiomic biomarker patterns
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Facial Swelling
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hepatic iron overload quantification
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Hepatic fat overload quantification
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Steps count
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 6MWT speed
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in the Area Under the Concentration vs. Time Curve
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Change from baseline Peak Expiratory Flow (PEF) at 8 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change from baseline Maximum Inspiratory Pressure (MIP) at 8 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change from baseline Maximum Expiratory Pressure (MEP) at 8 weeks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Degree of decrease in internal rotation contracture of the shoulder
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Percentage seizure-free
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neurological outcomes
Primary endpoint: Absolute Change From Baseline in 6-minute Walking Distance (6MWD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: nerve growth factor levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Difference in axilo-rectal temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Circadian Amplitude
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: REM Sleep Phenomena
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Objective Daytime Sleepiness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Doctor evaluations using the POSAS scoring range
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: changes in Il-36 levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Changes in functional status (Barthel Index)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Changes in functional status (Mini Mental State Evaluation)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Changes in functional status (GDS Yesavage)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Changes in functional status (Trail Making Test)
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Academic Performance
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Average number of late complications
Endpoint domain: Adverse events/effects
Primary endpoint: Repigmentation at surgery site
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Solicited local or systemic reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Vaccine Adherence
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Patency of the Target Lesion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Freedom From Clinically-Driven Target Lesion Revascularization (CD-TLR)
Endpoint domain: Adverse events/effects
Primary endpoint: Freedom From Unplanned, Unavoidable Major Amputation of the Index Limb
Endpoint domain: Adverse events/effects
Primary endpoint: Changes in BSS (Bronchitis Severity Score) - cough domain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Changes in BSS (Bronchitis Severity Score) total score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Number of MRI Related Patient Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Adverse Device Effects During MRI Visit
Endpoint domain: Adverse events/effects
Primary endpoint: Occurrence of FMT-related treatment emergent (serious) adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: HER2 Status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Fractional muscle protein synthesis and breakdown rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Net fractional muscle protein synthesis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Personal and Social Performance
Endpoint domain: Life impact
Endpoint subdomain: Social functioning
Primary endpoint: Maximal Insulin Secretion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Willingness to undergo chemotherapy
Endpoint domain: Life impact
Endpoint subdomain: Personal circumstances
Primary endpoint: Percentage of Subjects With at Least 4-fold Increase in Anti-Vi ELISA Titers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Amniotic fluid leaks
Endpoint domain: Physiological/clinical
Endpoint subdomain: Pregnancy and childbirth outcomes
Primary endpoint: Peroperative bloodloss
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Cell Concentration in Suction Skin Blister Fluid
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Levels of Inflammatory Mediators in Suction Skin Blister Fluid
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Persistence and Recurrence of Anal Warts
Endpoint domain: Adverse events/effects
Primary endpoint: long-term adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: plasma superoxide dismutase activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: plasma catalase activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Development of CSA-AKI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Consistent usability
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Incidence of adverse events associated with TCE use
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Absolute FEV1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Cough frequency and severity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change of sputum
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Lung snoring
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Neutrophil response (influx of PMNs to the airways)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: AUCτ,ss of Rosuvastatin and Telmisartan, Amlodipine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cmax, ss of Rosuvastatin and Telmisartan, Amlodipine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in job strain
Endpoint domain: Life impact
Endpoint subdomain: Role functioning
Primary endpoint: Incidence of complicated filter retrieval
Endpoint domain: Adverse events/effects
Primary endpoint: Maximal Thoracic Apical Deviation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Hb response rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Number of Subjects With Any Serious Adverse Events (SAEs) From Day 1 up to Day 61
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Subjects With Hematological Laboratory Results Change With Respect to Normal Laboratory Ranges and Versus Baseline
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Amount of fructose escaping first-pass hepatic extraction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Counting of lymphocyte populations (pre-chemotherapy)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Counting of lymphocyte populations (post-chemotherapy)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Incidence of retinopathy of prematurity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Ophthalmological outcomes
Primary endpoint: Booster effect ratios of GMT
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change from baseline in IC
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Percent predicted FEV1
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Fecal Calprotectin levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: number of bacteria
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Proteins in the aqueous humor
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Incidence of Acute Cellular Rejection
Endpoint domain: Adverse events/effects
Primary endpoint: Proportion of patients with CR or PR as best overall response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Inadequate health literacy
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change From Baseline in Forced Vital Capacity (FVC) Rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: mMASI Scoring
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Number of Days Alive Without Renal, Hemodynamic, or Electrical Clinical Worsening
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Changes in perceived pain intensity
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Safety laboratory tests
Endpoint domain: Adverse events/effects
Primary endpoint: Average Change From Baseline in Modified Ashworth Scale-Bohannon (MAS-B) Score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Musculoskeletal and connective tissue outcomes
Primary endpoint: Major adverse cardiac and/or cerebrovascular events (MACCE)
Endpoint domain: Adverse events/effects
Primary endpoint: Left to right flow through the device
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Dosimetric efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in MDS-UPDRS part III score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes