TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: feasibility of surveying clinicians
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: range of team situational awareness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction of overall symptoms
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PVI (Pleth Variability Index)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: PPV (Pulse Pressure Variation)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Prevalence of affective and anxiety disorders
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Prevalence of adjustment disorder
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Prevalence of substance use disorders
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Overall GI symptom score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Indwelling time
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Device related serious adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: Physician Global Assessment (PGA) Score of Clear/Almost Clear
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Impact of Dermatological Disease on Quality of Life (DLQI ≤5)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Changes in transcriptome profile of hypothalamic cells
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Victorian Institute of Sports Assessment (VISA-P) score
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Cerebellum Dependent Associative Learning (% CRs)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Completion of the Grooved Pegboard Motor Task (Reaction Time/Accuracy)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: CANTAB Motor Screening Test (Reaction Time)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change of Quality of Life Over Time
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change of Self Management Skills Over Time
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Improvements in Preventable Conditions
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: walking steps and walking time
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Acceptability of social needs screening
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Number of adverse events (AE)
Endpoint domain: Adverse events/effects
Primary endpoint: Time to First Atrial Fibrillation (AF) Recurrence or Atrial Flutter Emergence
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Number of days bleeding
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mean Change in Daily Evening Peak Expiratory Flow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Number of Participants With Non Serious Adverse Events (Non-SAEs) and Serious Adverse Events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants With Worst Case Hematology Parameters of Potential Clinical Importance (PCI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Change From Baseline in Activated Partial Thromboplastin Time and Prothrombin Time at Indicated Time Points
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Pain assessed by NRS
Endpoint domain: Life impact
Endpoint subdomain: Fatigue
Primary endpoint: Percentage of Participants with Complete Resection After IDS
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Percentage of Participants with Different CC Scores After IDS
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: pain free time
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: early tumour response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Incidence of defined adverse events
Endpoint domain: Adverse events/effects
Primary endpoint: 18F-Fluoride activity
Endpoint domain: Physiological/clinical
Endpoint subdomain: Bone and joint outcomes
Primary endpoint: Incidence of hypotension after anesthesia induction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Forced Expiratory Volume in 1 Second (FEV1) AUC0-4h
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Efficacy of Flutiform pMDI 50/5μg
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: voiding and storage symptoms improvement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: sexual function changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Amplitude of displacement of thoraco-abdominal compartments
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: neuropathic pain yes/no
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: grading of pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in burden of caregivers
Endpoint domain: Life impact
Endpoint subdomain: Societal/carer burden
Primary endpoint: Maximum plasma drug concentration (Cmax) of sotagliflozin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area under curve (AUC) of sotagliflozin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Postoperative RUQ Pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Post-Discharge Readmission
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Gastrointestinal Side Effects and Quality of Life (Total Score of GSRS)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Number of Participants With Cytomegalovirus Infection or Disease
Endpoint domain: Adverse events/effects
Primary endpoint: Safety of anti-CD-20
Endpoint domain: Adverse events/effects
Primary endpoint: Clinical progression measured as Constant score change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to Sterilization of CSF
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of patients with CDAI < 150
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Auditory Hallucinations reduction
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Modified Borg Scale of Perceived Exertion
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 6 Min walk test (Distance in meters)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Macular thickness measurement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: ST-segment elevation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Volume of blood products transfused
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Endotracheal intubation success rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Pittsburgh sleep quality index (PSQI) score
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Change in Hamilton Depression Scale (HAMD-17) score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Clearance of sodium and lithium
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Fractional excretion of sodium and lithium
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Maximum tolerated dose (MTD) of JAK2 inhibitor WP1066
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of adverse events assessed using NCI CTC
Endpoint domain: Adverse events/effects
Primary endpoint: Rate of skin and soft tissue infections
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: Echogenicity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Major pathologic response (mpCR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Reversal of Cholestasis
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage Change of the Total Score of the Grading Scales for Meibomian Gland Dysfunction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pharmacokinetic profile of levosimendan and its metabolites
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of MRSA and EESBL infections
Endpoint domain: Adverse events/effects
Primary endpoint: Successful removal of all stones from the bile duct
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Insulin sensitivity indices (HOMA IR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Visual field mean deviation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Pervasive Developmental Disorders Screening Test-II Stage 2
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Brief Infant-Toddler Social and Emotional Assessment (BITSEA)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Maximum Tolerated Dose (MTD) of clarithromycin
Endpoint domain: Adverse events/effects
Primary endpoint: Erythrocyte Glutathione Reductase Activation Coefficient
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Intracranial disease progression time
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Proportion of time spent in normoxemia (85-92%)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Diet-related greenhouse gas emissions
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Diet-related land use
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Diet-related water use
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Frequency of Satisfying Sexual Events
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: N-Back Task
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Phase angle as an indicator of nutrition status
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Incidence of violence or aggression by patients directed towards emergency staff
Endpoint domain: Adverse events/effects
Primary endpoint: Incidence of violence or aggression by patients's accompanying persons directed towards emergency staff
Endpoint domain: Adverse events/effects
Primary endpoint: Change in proportion of CD59 on the endothelial cell surface
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Trough Plasma Levels (Ctrough) of Calcitriol
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: The Observed Peak Drug Concentration (Cmax) of Calcitriol
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Area Under the Concentration-Time Curve From Pre-Application (T0) Through 9 Hours Post Dosing (AUC [0-9 Hours])
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Concentration of cytokines
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Number of new prescriptions for FDA-Approved osteoporosis medications
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Efficacy of nitroprusside gel in improving IUD insertion experience
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tolerability of nitroprusside gel
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Patient Activation in Care (PAM)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in Health Status (SF-12v2™): Physical Health Sub-scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in Health Status (SF-12v2™): Mental Health Sub-scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: PK parameters of buprenorphine
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intoxication and withdrawal
Endpoint domain: Adverse events/effects
Primary endpoint: Reduction in clinical patch test score for dermatitis
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Reduction in severity of eczema using the PGA score
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change from Baseline Health knowledge score
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Proportion of patients with modified Rankin scale (mRS) ≤2
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percentage of patients reaching BP goal
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Percentage of patients with HbA1c <7% and no severe nocturnal hypoglycemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: HI Antibody Titre Seroconversion Rate After the First Vaccination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: HI Antibody Titre Seroconversion Rate After the Second Vaccination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Percentage of Participants Achieving a HI Antibody Titre of 1:40 or More After the First Vaccination
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Infant survival rate
Endpoint domain: Mortality/survival
Primary endpoint: GAD7 score change
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Assessment of anesthesia depth
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Tinnitus Functional Index (TFI)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Iowa Tinnitus Handicap Questionnaire version 1 (ITHQ)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Zung Self-Rating Depression Scale (SDS)
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: World Health Organization Quality Of Life (WHOQOL)-BREF
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Number of Subjects With Post-surgical Otorrhea
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Subjects' Anxiety State
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: changes of blood metabolomics
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Level of health promotion
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Disease prevention
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Acceptability and usefulness of both the CHAP health review and the ASK Diary
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Average blood pressure readings
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in Score in Spence Children's Anxiety Scale
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change From Baseline in Body Mass Index (BMI) at Week 52
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in Glycosylated Hemoglobin (HbA1c) at Week 52
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Number of Participants With Extrapyramidal Symptoms
Endpoint domain: Adverse events/effects
Primary endpoint: Difference in percentage of sessions that were attended
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: Incidence of Pulmonary Embolism
Endpoint domain: Mortality/survival
Primary endpoint: Maximal Change in NRS Pain Scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Cesarean rate
Endpoint domain: Mortality/survival
Primary endpoint: Conclusive diagnosis of Fabry disease
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Local Injection Site Reactions
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Who Discontinue Study Drug or Withdraw From the Study
Endpoint domain: Adverse events/effects
Primary endpoint: Plasma level of kidney injury molecule-1 (KIM-1)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Renal and urinary outcomes
Primary endpoint: Mean changes in respiratory tidal volume
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Changes in intraoperative management practices
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Biphasic Alcohol Effects Scale - Stimulation
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Profile of Mood States - Vigor
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Subjective High From Alcohol Scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in CSF Abeta42
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change From Baseline in CSF Total Tau
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change From Baseline in CSF P-tau181
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change From Baseline in CSF Neurogranin
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change From Baseline in CSF Neurofilament Light Chain
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Change in fasting plasma HDLc concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change in Glycated Hemoglobin (HbA1c) (%)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Accuracy of liver ultrasound in predicting VOD
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in area under the curve after meal challenge
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in salivary proteins
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Dementia Pain Management Knowledge Score
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Tolerability of Low dose Radiotherapy
Endpoint domain: Adverse events/effects
Primary endpoint: Standardized phase angle measure
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Duration of noninvasive mechanical ventilation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: 3-hr postprandial glucose response
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Percentage of time participants spend within the therapeutic INR range
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: SpO2/FIO2 increment
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: RR change
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: vascular reactivity of brachial artery
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: occurrence of cough
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Reduction of back and leg pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: MRI defined failure of the cuff repair
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Total Drain Days
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Total Drain Output
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Reduction in inflammatory cytokines
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Average Adequate Relief Rate
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Adequate Relief of IBS Pain and Discomfort
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Ratings on Irritable Bowel Syndrome Quality of Life (IBSQoL) Scale
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Duration of Tofacitinib Drug Survival
Endpoint domain: Mortality/survival
Primary endpoint: Efficacy Endpoint
Endpoint domain: Physiological/clinical
Primary endpoint: Levels of pain
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: maximum tolerated dosage (MTD)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Improvement in bowel management
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes