TrialPanorama/TrialPanorama-database huggingface dataset:
Primary endpoint: Adherence to TDF at 3-months on PrEP
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Adherence to TDF at 6 Months Post-partum
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Adherence to TFV-DP at 6-month Visit
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent of Cases with Changes in Treatment Recommendation
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Skin temperature in supra-clavicular region in basal condition (TSCRbasal)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Skin temperature in supra-clavicular region during a cold test (TSCRcold)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Baseline difference in skin temperature in supra-clavicular region (diff TSCR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overall Tumor Response Rate (ORR)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Change in Beck Depression Inventory score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: leak fraction
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quality of palliative care
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Charcot Marie Tooth Neuropathy Score (CMTNS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Normalization of blood testosterone levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Endocrine outcomes
Primary endpoint: Change From Baseline in the 7-day mean score for pelvic pain
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Internalized stigma
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Tenofovir-diphosphate (TFV-DP) Levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Respiratory symptoms and related physical limitation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: PHQ-9 Total Scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Patient or Caregiver Activation at Discharge
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Potential Post-Discharge Adverse Events
Endpoint domain: Adverse events/effects
Primary endpoint: Time to reach maximum plasma concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum PCSK9 concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Microcirculatory flow index of small and medium vessels
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: epileptogenicity index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Rate of recurrence of atrial fibrillation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Length of time to first recurrence of atrial fibrillation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Two-year Disease Free Survival
Endpoint domain: Mortality/survival
Primary endpoint: Melasma Area and Severity Index
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change of symptom score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in vomiting scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Pain level measured by visual analog scale
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: 6 Minute Walk Test (6 MWT) distance
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Rate of structural and functional changes to retinal thickness
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: CDAI Clinical Response -100 at Week 8
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Single Leg Squat Test (SLS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stabilometry variable x displacement open eyes before dry needling
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stabilometry variable y displacement open eyes before dry needling
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Stabilometry variable center of pressure area open eyes before dry needling
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Safety Outcomes
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Hamilton Depression Rating Scale-17 Item
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Change in PTSD Checklist score
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Feasibility (patient perspective)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Feasibility (clinician perspective)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Acceptability (patient perspective)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Satisfaction (patient perspective)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: measured skin temperature
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Change From Baseline in Weekly Average of (Daily) Average Pain Intensity (WAAPI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Local tumor progression (LTP) rates
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Clinical outcome measure of disability
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Overjet
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Visual analogue pain scale at rest and on movement
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to AVF Primary Unassisted Patency
Endpoint domain: Physiological/clinical
Endpoint subdomain: Vascular outcomes
Primary endpoint: Number of patients correctly identified as low axillary tumor load carriers by ultrasound imaging workflow
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Number of patients correctly identified as low axillary tumor load carriers by tumor load information
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Number of patients correctly identified as low axillary tumor load carriers by combined methods
Endpoint domain: Physiological/clinical
Endpoint subdomain: Blood and lymphatic system outcomes
Primary endpoint: Efficacy and safety of GM-CT-01
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: B-type lines on thoracic ultrasound
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Intraepidermal fiber density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Autonomic function
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Discovery of Lesions on brain MRI
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Number of Participants With Major Adverse Cardiovascular Event (MACE)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Participants Who Used the Test Product at Correct Age (18 Years or Older)
Endpoint domain: Resource use
Endpoint subdomain: Need for further intervention
Primary endpoint: Number of Participants Who Did Not Exceed the Correct Frequency of Use (2 Sprays Per Nostril Per Day)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of Participants With Improved Symptoms Who Reduced the Doses to 1 Spray Per Nostril Per Day
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Time to first detection of CMV infection or disease within 6 months post-prophylaxis
Endpoint domain: Adverse events/effects
Primary endpoint: Time to first detection of CMV infection or disease within 18 months post-transplant
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Plasma Protoporphyrin IX Level
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: TNF-α concentrations in plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Cuff pressure values
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Number of measurements outside target range
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Procedural and long-term safety
Endpoint domain: Adverse events/effects
Primary endpoint: Change in clinical characteristics of scleroderma patients
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change in baseline pain intensity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sino-Nasal Outcome 20 (SNOT-20)
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: composite of death or readmission
Endpoint domain: Mortality/survival
Primary endpoint: Change in Deep Sleep
Endpoint domain: Life impact
Endpoint subdomain: Sleep
Primary endpoint: Six-Month Symptomatic Radiation Necrosis Proportion
Endpoint domain: Adverse events/effects
Primary endpoint: Frequency of vaccine-related solicited adverse events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Severity of vaccine-related solicited adverse events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Frequency of vaccine-related lower respiratory illness
Endpoint domain: Adverse events/effects
Primary endpoint: Tumor Infiltrating T Lymphocyte (TIL) Density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Cell Cycle and Cancer Proliferation Genetic Signature
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: intensity of the treatment burden perceived by residents
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Change in oxygenation index (OI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change in Liebowitz Social Anxiety Scale scores
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Pinch-holding-up activity (PHUA) test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Semmes-Weinstein monofilament (SWM)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Purdue Pegboard test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Michigan Hand Outcomes Questionnaire (MHQ)
Endpoint domain: Life impact
Endpoint subdomain: Physical functioning
Primary endpoint: Diabetes-39 (D-39)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Moving two-point discrimination (M2PD) test
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: DNA Repair Enzyme Signature biomarkers profiles
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Number of Subjects With at Least One Incidence of Treatment-Emergent Adverse Events (TEAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Subjects Who Withdraw Due to Adverse Events (AEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Number of Subjects With at Least One Incidence of Serious Adverse Events (SAEs)
Endpoint domain: Adverse events/effects
Primary endpoint: Patient's Impression of Change
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Changes from baseline in pulse rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Skeletal-related Event-free Survival
Endpoint domain: Mortality/survival
Primary endpoint: Percent of IgG With Galactosylation, Fucosylation and/or Sialylation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Severity of symptoms of common cold
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Occurrence of permanent pacemaker implantation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes
Primary endpoint: Percentage of acceptance of a COVID-19 vaccine
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Hepatitis C virus (HCV) RNA levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Infections and infestations outcomes
Primary endpoint: changes in the baroreflex
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change in coefficient of fecal fat absorption
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: Percent carbon dioxide expired by 13C-mixed triglyceride breath test
Endpoint domain: Physiological/clinical
Endpoint subdomain: Gastrointestinal outcomes
Primary endpoint: rate of change in the absolute diameter of the aortic root and ascending aorta
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: change in systolic 24-h ambulatory BP
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Mean percentage change of Psoriasis Areas Severity Index (PASI)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Magnitude of the Analgesic Effect (NRS Pain Intensity)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Intra-abdominal bleeding
Endpoint domain: Adverse events/effects
Primary endpoint: Intra-abdominal infection
Endpoint domain: Adverse events/effects
Primary endpoint: Prevalence of Sleep Disordered Breathing (SDB)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Presence of unknown substrate in exhalation sample
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Incidence of dose-limiting toxicities (DLT)
Endpoint domain: Adverse events/effects
Primary endpoint: Depression severity measured by HamD29
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: Warm Detection Thresholds
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain to Supra-threshold Heat Stimuli
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Mechanical Pain Thresholds and Sensitivity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Trans-epidermal Water Loss (TEWL)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Skin and subcutaneous tissue outcomes
Primary endpoint: Plasma PK parameters (AUC, tmax, Cmax, t1/2)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Evoked Related Potentials
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Response to Onset of Effect Questionnaire items 2 and 5
Endpoint domain: Life impact
Endpoint subdomain: Perceived health status
Primary endpoint: Wound State
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: DFU wound recurrence
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Exacerbation events
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Lung density
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Cmax of Fimasartan, Amlodipine and Rosuvastatin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AUCt of Fimasartan, Amlodipine and Rosuvastatin
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change of best-corrected visual acuity
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Fasting Blood Lipid Profiles (TG levels)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: One-year progression-free survival (PFS) rate
Endpoint domain: Mortality/survival
Primary endpoint: Total amount of bacterial species in peri-implantitis processes
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: ALA change
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Quality of Life (EORTC QLQC30)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Quality of Life (EORTC QLQCR29)
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Number of Participants With Target Lesion Failure (TLF)
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Time-saving associated with the two procedures
Endpoint domain: Resource use
Endpoint subdomain: Other resource use
Primary endpoint: time spent in safe blood glucose range
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: recurrent VTE including DVT and PE
Endpoint domain: Mortality/survival
Primary endpoint: Major Bleeding (MB)
Endpoint domain: Adverse events/effects
Primary endpoint: Clinical Relevant Non Major Bleeding (CRNMB)
Endpoint domain: Adverse events/effects
Primary endpoint: sphingolipid levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Retinal microvessels density
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Change From Baseline in Average AM and PM Subject-reported 12-hour Reflective Total Nasal Symptom Score (rTNSS)
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Assessment of Skills and Knowledge
Endpoint domain: Life impact
Endpoint subdomain: Cognitive functioning
Primary endpoint: Safety and reactogenicity of AdCh3NSmut and Ad6NSmut
Endpoint domain: Adverse events/effects
Primary endpoint: Change in Viral Load
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change in Immunoglobulin G COVID-19 Titers
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Change from baseline in weekly mean SBM frequency
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Pain Score with dressing changes
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Forgotten joint score
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: VS-EFP regulation success
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Heart rate compliance ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Attachment Gain
Endpoint domain: Life impact
Endpoint subdomain: Emotional functioning/wellbeing
Primary endpoint: incidence of critical illness neuromuscular abnormalities
Endpoint domain: Physiological/clinical
Endpoint subdomain: Nervous system outcomes
Primary endpoint: Cavernous sinus invasion
Endpoint domain: Physiological/clinical
Endpoint subdomain: Neoplasms and related outcomes
Primary endpoint: Paclitaxel pharmacokinetics
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: self-management skills
Endpoint domain: Life impact
Endpoint subdomain: null
Primary endpoint: Headache Scores
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Sensitivity and specificity of CAPTURE
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: AR-67 half life in tumor and plasma
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Percent of Patients Who Reach Consensus Target HBA1c
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Sensitivity and specificity to predict Level 1 hypoglycemia
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Core temperature achievement ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Influenza vaccination efficacy
Endpoint domain: Physiological/clinical
Endpoint subdomain: Immune system outcomes
Primary endpoint: Rate of change in the number of binge days per week
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Self-reported subsequent falls
Endpoint domain: Adverse events/effects
Primary endpoint: Solicited Adverse Events Following Vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: Unsolicited Adverse Events Following Vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: Serious Adverse Events Following Vaccination
Endpoint domain: Adverse events/effects
Primary endpoint: Quality of Life (FAC-G7) questionnaire
Endpoint domain: Life impact
Endpoint subdomain: Global quality of life
Primary endpoint: Change from baseline oxygen uptake
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change from baseline respiratory exchange ratio
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change from baseline ventilation
Endpoint domain: Physiological/clinical
Endpoint subdomain: Respiratory outcomes
Primary endpoint: Change from baseline heart rate
Endpoint domain: Physiological/clinical
Endpoint subdomain: Cardiovascular outcomes
Primary endpoint: Change from baseline blood lactate concentration
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Change from baseline stride length
Endpoint domain: Physiological/clinical
Endpoint subdomain: General outcomes
Primary endpoint: Serum amino acid, acylcarnitine and thyroxine levels
Endpoint domain: Physiological/clinical
Endpoint subdomain: Metabolic and nutritional outcomes
Primary endpoint: Radiographic assessments of fusion and instability
Endpoint domain: Physiological/clinical
Endpoint subdomain: Surgical and medical procedures outcomes