TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT02989012

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GanMaoKangNing Granules
Description: 3 times a day, 2 bags each time.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Analogous Oseltamivir Phosphate Capsules
Description: 2 times a day,1 capsule each time.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Oseltamivir Phosphate Capsules
Description: 2 times a day,1 capsule each time.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Analogous GanMaoKangNing Granules
Description: 3 times a day, 2 bags each time.
Study: NCT06200584

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olanzapine
Description: Antipsychotic Agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quetiapine
Description: Antipsychotic Agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risperidone and Vitamin D and Vitamin E
Description: vitamin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olanzapine and Vitamin D and Vitamin E
Description: vitamin and Antipsychotic agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quetiapine and Vitamin D and Vitamin E
Description: Vitamin and Antipsychotic agents
Study: NCT05181579

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manuel therapy
Description: Some sacroiliac manipulation and mobilization techniques will be applied to patients by an experienced physiatrist. Patients in the manual therapy group will receive 5 sessions of sacroiliac joint manipulation once a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sacroiliac joint injection
Description: Corticosteroid (1 ml 40 mg methylprednisolone) and local anesthetic (1 ml 1% lidocaine) will be injected into the sacroiliac joint using a 22 G spinal needle, guided by fluoroscopy (C-arm fluoroscopy) by an experienced physiatrist. It will be applied just one time.
Study: NCT05579080

Intervention type: DEVICE
Intervention: noninvasive ventilation
Description: The medical records whose patients used some type of non-invasive ventilatory device and devices that promote oxygen supplementation will be analyzed.

Intervention type: DEVICE
Intervention: noninvasive ventilation
Description: The medical records whose patients used some type of non-invasive ventilatory device and devices that promote oxygen supplementation will be analyzed.

Intervention type: DEVICE
Intervention: noninvasive ventilation
Description: The medical records whose patients used some type of non-invasive ventilatory device and devices that promote oxygen supplementation will be analyzed.

Intervention type: DEVICE
Intervention: noninvasive ventilation
Description: The medical records whose patients used some type of non-invasive ventilatory device and devices that promote oxygen supplementation will be analyzed.
Study: NCT05741060

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-equol
Description: Experimental drug

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo - 10 mg per day for 24 months of tablets that will be the same size/shape/color as the s-equol tablets.
Study: NCT06343558

Intervention type: OTHER
Intervention: Questionnaires, clinical scales and instrumental tests
Description: Questionnaires, clinical scales and instrumental tests to collect a wide range of balance and gait measures.

Intervention type: OTHER
Intervention: Questionnaires, clinical scales and instrumental tests
Description: Questionnaires, clinical scales and instrumental tests to collect a wide range of balance and gait measures.

Intervention type: OTHER
Intervention: Questionnaires, clinical scales and instrumental tests
Description: Questionnaires, clinical scales and instrumental tests to collect a wide range of balance and gait measures.

Intervention type: OTHER
Intervention: Questionnaires, clinical scales and instrumental tests
Description: Questionnaires, clinical scales and instrumental tests to collect a wide range of balance and gait measures.

Intervention type: OTHER
Intervention: Questionnaires, clinical scales and instrumental tests
Description: Questionnaires, clinical scales and instrumental tests to collect a wide range of balance and gait measures.
Study: NCT04868461

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Unheated Whey Protein (UWP) beverage
Description: The preload is made from whey protein powder. The energy load of the preload is 119.7 kcal and has banana flavor and sweetener.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Heated Whey Protein (HWP) beverage
Description: The preload is made from whey protein powder of 95% and it is heated for a certain amount of time. The energy load of the preload is 119.7 kcal and has banana flavor and sweetener.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Casein (Cas) beverage
Description: The preload is made from casein powder. The energy load of the preload is 105 kcal and has banana flavor and sweetener.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Water
Description: The preload is water acting as a control and contain the same banana flavor and sweetener to match the other three intervention - protein beverages.
Study: NCT06056791

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: INKmune
Description: INKmune is a patented biologic delivery system and method for cancer treatment using in vivo priming and activation of natural killer (NK) cells in order to achieve tumor cell lysis. INKmune is a suspension of INB16 cells which have been rendered replication incompetent that does not require donor matching.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: INKmune
Description: INKmune is a patented biologic delivery system and method for cancer treatment using in vivo priming and activation of natural killer (NK) cells in order to achieve tumor cell lysis. INKmune is a suspension of INB16 cells which have been rendered replication incompetent that does not require donor matching.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: INKmune
Description: INKmune is a patented biologic delivery system and method for cancer treatment using in vivo priming and activation of natural killer (NK) cells in order to achieve tumor cell lysis. INKmune is a suspension of INB16 cells which have been rendered replication incompetent that does not require donor matching.
Study: NCT05939804

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TENS
Description: TENS will be applied to the experimental group on the 0th and 1st days after the surgery, and the pain assessment at the time of movement/rest before and after the procedure will be made by the researcher.
Study: NCT06012578

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ISM5411
Description: Investigational Drug

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: ISM5411 Matching Placebo
Study: NCT04835038

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Bicarbonate Ringer's Injection
Description: Intraoperative fluid therapy performed with BRS (Sodium Bicarbonate Ringer's Injection)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sodium Lactated Ringer's Injection
Description: Intraoperative fluid therapy performed with LRS (Sodium Lactated Ringer's Injection)
Study: NCT06540196

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: NodeAI
Description: The ultrasound video and images of each LN will be analyzed by NodeAI, which will assign a CLNS for each LN based on the four ultrasonographic features of the CLNS, predict LN malignancy, and determine whether to biopsy it or not.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Surgeon
Description: The ultrasound video and images of each LN will first be analyzed by the surgeon, who will assign a CLNS for each LN based on the four ultrasonographic features of the CLNS, predict LN malignancy, and determine whether to biopsy it or not.
Study: NCT06028646

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dynamic Airway CT scan (DA-CT)
Description: Patient will be asked to perform movements during the scan.
Study: NCT05840276

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryoneurolysis
Description: The VISUAL-ICE uses a combination of argon and helium, to create a highly localized cold zone with temperatures between -20 and -100°C. A probe will be inserted percutaneously at the target AFCN and IBSN guided by ultrasound visualization to accurately determine the location of the nerve and to account for adjacent neurovascular structures and variations in anatomical structures. The target locations are drawn directly on the patients' skin prior to treatment along which a dose of local anesthetic will be injected subcutaneously before treatment. Cryoneurolysis at each target site requires 2 freeze cycles with a duration of 3 mins, and with thaw cycles between 20-40 seconds.
Study: NCT04630652

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risankizumab-Rzaa
Description: Risankizumab at a dose of 150 mg with injections administered at baseline, week 4 and week 16 following FDA-approved dosage and time periods

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Punch biopsies of the skin at baseline visit
Description: Two 6 mm punch biopsies of the skin at baseline visit

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Punch biopsies of the skin at week 28 visit
Description: One 6 mm punch biopsy of the skin at week 28 visit
Study: NCT06510517

Intervention type: OTHER
Intervention: Calculation of Mechanical Power.
Description: Total respiratory rate (RR). Positive end-expiratory pressure (PEEP) (the external or applied PEEP) recorded, not the total PEEP, or intrinsic PEEP. The plateau pressure (Pplat) was measured during an inspiratory pause on the ventilator. Peak inspiratory pressure (Ppeak) should be obtained while the patient is relaxed, not coughing or moving in bed. MP was calculated according to Gattinoni's simplified mechanical power equation as follows (3,8):~MP(J/min)=0.098×VT×RR×(Ppeak-0.5×ΔP).

Intervention type: OTHER
Intervention: Measurement Diaphragmatic Excursion after first SBT
Description: Chest ultrasound to assess diaphragmatic excursion (DE(. M-mode was used to record the movement of the diaphragm during tidal breathing when the sampling line and diaphragm were as vertical as possible (not \< 70°). The data was measured from the first respiratory cycle at 0 min after SBT. The DE at 0 min, 5 min, and 30 min of SBT was respectively named as DE0, DE5, and DE30. The variation of right DE between each time point was named as ΔDE30-5 and ΔDE30-0. (7)
Study: NCT05840276

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: A sham needles will be inserted percutaneously at the target AFCN and IBSN guided by ultrasound visualization. The target locations are drawn directly on the patients' skin prior to treatment along which a dose of local anesthetic will be injected subcutaneously before treatment. Sham will simulate cryoneurolysis at each target site for 2 freeze cycles with a duration of 3 mins, and also simulate thaw cycles between 20-40 seconds. No temperature changes will actually occur although the experience and sounds will be similar to cryoneurolysis
Study: NCT06001801

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Prevention Program
Description: The DPP group is led by the Community Health and Social Services Center (CHASS) community health workers (CHWs). For this study, the workers will deliver 16 weekly sessions (core phase) followed by two monthly sessions (maintenance phase). Each session lasts one hour plus the time required to weigh each participant and review food and activity logs.~This program will help participants make healthy lifestyle changes. Examples are improvements in eating and physical activity. The goal is that participants lose some weight and eat healthier food.~Sessions will be offered in-person in a room with video capacity to allow attendance of participants that cannot attend in person. For those participating virtually, the CHWs will briefly review with them what participants logged.~Participation in this project should last approximately 6-months.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diabetes Prevention Program
Description: The DPP group is led by the Community Health and Social Services Center (CHASS) community health workers (CHWs). For this study, the workers will deliver 16 weekly sessions (core phase) followed by two monthly sessions (maintenance phase). Each session lasts one hour plus the time required to weigh each participant and review food and activity logs.~This program will help participants make healthy lifestyle changes. Examples are improvements in eating and physical activity. The goal is that participants lose some weight and eat healthier food.~Sessions will be offered in-person in a room with video capacity to allow attendance of participants that cannot attend in person. For those participating virtually, the CHWs will briefly review with them what participants logged.~Participation in this project should last approximately 6-months.
Study: NCT06026358

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tirbanibulin
Description: subjects receive 2,5 mgTirbanibulin in 250 mg ointment with daily administration of one single sachet on the left hand and 250mg ointment placebo on the right hand for 5 d in a single-blinded manner.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirbanibulin
Description: subjects receive 2,5 mgTirbanibulin in 250 mg ointment with daily administration of one single sachet on the left hand and 250mg ointment placebo on the right hand for 5 d in a single-blinded manner.
Study: NCT05639023

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manipulation Techniques
Description: Subjects will received 12 times orthopedic manipulation. Three times of treatment per months, and less than twice a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy Scoliosis-Specific Exercise
Description: Subjects will receive 14 supervise training, 5 times of intensive supervise training for first two weeks and then 1-2 trainings per month for the rest. Subjects are encouraged to perform home exercise everyday on their own throughout the study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy Scoliosis-Specific Exercise
Description: Subjects will receive 14 supervise training, 5 times of intensive supervise training for first two weeks and then 1-2 trainings per month for the rest. Subjects are encouraged to perform home exercise everyday on their own throughout the study.
Study: NCT05165069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mecobalamin 5 MG Disintegrating Oral Tablet
Description: Mecobalamin 0.5mg / time, 3 times / day,was taken continuously for 6 months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo 0.5mg / time, 3 times / day,was taken continuously for 6 months
Study: NCT05784155

Intervention type: DRUG
Group type: OTHER
Intervention: Test Drug(JW0302) or Reference Drug(C2206)
Description: Test Drug: single administration of JW0302 Reference Drug: single administration of C2206~Tablet, Oral, QD for 1 Days, Washout period is more than 14 days after administration

Intervention type: DRUG
Group type: OTHER
Intervention: Test Drug(JW0302) or Reference Drug(C2206)
Description: Test Drug: single administration of JW0302 Reference Drug: single administration of C2206~Tablet, Oral, QD for 1 Days, Washout period is more than 14 days after administration
Study: NCT06256445

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Polyene Phosphatidylcholine
Description: Formulated as an injectable solution containing Polyene Phosphatidylcholine at concentration of 25 mg/mL

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching placebo of AYP-101
Description: Phosphate buffered saline placebo for injection
Study: NCT05462483

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rice Sock and Instructions to heat the quadriceps.
Description: A rice sock will be provided to the experimental group to heat the quadriceps 3x per day for six weeks. The participants will be encouraged to heat before and after rehabilitation exercises as well.
Study: NCT06048055

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous auricular vagus nerve stimulation
Description: Patients in this group will be treated with 12 sessions of transcutaneous auricular nerve stimulation, three sessions per week for four weeks. The stimulation of the left auricular branch of the vagus nerve will be performed by conventional transcutaneous electrical nerve stimulation (TENS) through a Gamna Duo 200 electrotherapy device with one channel and two electrodes (5mm diameter disposable adhesive stimulation electrodes). The TENS parameters will be used: 30 30-minute treatment time, a pulse width of 200 milliseconds, and a pulse frequency of 20 hertz. The intensity of stimulation will be individually adjusted according to the patient's perceptual threshold. The perceptual threshold (PT) is defined as the minimum amount of electricity required to perceive electrical stimulation on the skin described as a pricking or tingling sensation. The stimulation intensity will be set at super-threshold levels, such as 200% of the patient's perceptual threshold.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: selected physical therapy program
Description: The selected physical therapy program session will be from 25 to 30 minutes, three sessions per week for four weeks. The program will be selected mainly for stretching for shortened upper limb muscles, strengthening for weak upper limb muscles, occupational therapy for hand, trunk, and pelvic control exercises, and gait training.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: selected physical therapy program
Description: The selected physical therapy program session will be from 25 to 30 minutes, three sessions per week for four weeks. The program will be selected mainly for stretching for shortened upper limb muscles, strengthening for weak upper limb muscles, occupational therapy for hand, trunk, and pelvic control exercises, and gait training.
Study: NCT06378372

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music therapy based on piano learning
Description: The intervention will consist of pianistic training. Patients will receive piano classes adapted to their competence designed to achieve motor, sensory and behavioral control.
Study: NCT04057456

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo diet
Description: The dietitian will assist in developing a diet that is isocaloric to the anti-inflammatory diet and healthy (for the sake of the participants' well-being, and to blind participants), while allowing many foods that are (counterintuitively) pro-inflammatory (e.g. whole wheat bread, white beans, oats, soy, eggplant, raspberries, pumpkin seeds, popcorn, etc). Occasional cheat foods are built into the placebo diet but with more pro-inflammatory options (e.g. two glasses of wine per week).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo diet
Description: The dietitian will assist in developing a diet that is isocaloric to the anti-inflammatory diet and healthy (for the sake of the participants' well-being, and to blind participants), while allowing many foods that are (counterintuitively) pro-inflammatory (e.g. whole wheat bread, white beans, oats, soy, eggplant, raspberries, pumpkin seeds, popcorn, etc). Occasional cheat foods are built into the placebo diet but with more pro-inflammatory options (e.g. two glasses of wine per week).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Anti-inflammatory diet
Description: Participants will also be given a list of foods that they are allowed on the anti-inflammatory diet, and a list of foods to avoid so that they can make informed substitutions to the meals and ingredients that they are given. The study participants will be given a one-week meal plan with accompanying recipes. Occasional cheat foods are built into the anti-inflammatory diet (e.g. two bottles of beer per week)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Anti-inflammatory diet
Description: Participants will also be given a list of foods that they are allowed on the anti-inflammatory diet, and a list of foods to avoid so that they can make informed substitutions to the meals and ingredients that they are given. The study participants will be given a one-week meal plan with accompanying recipes. Occasional cheat foods are built into the anti-inflammatory diet (e.g. two bottles of beer per week)
Study: NCT06001801

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: INSPIRA
Description: This intervention will include the DPP plus additional interventions. The additional interventions include: participants to stay for an extra 30 minutes following the regular DPP sessions. In these INSPIRA sessions, participants will be trained in providing mutual peer support, be matched with a peer partner and asked to talk at least once a week, receive vouchers or gift cards, discuss participants action plans with the peer partner, and share challenges, successes, and tips from the CHW and others in the session.~CHWs will provide brief trainings on autonomy-supportive peer support approaches over the first three weeks of sessions.~Participation in this project should last approximately 6-months.
Study: NCT04832971

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-ANG3
Description: ARO-ANG3 Injection
Study: NCT04057456

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nabilone Capsules
Description: Capsules will be 0.5mg nabilone. Participants will undergo a 5-week titration period by taking 1 (0.5mg) nabilone capsule per day for a three-day period. The dose will be increased on a fixed schedule by 1 (0.5mg) capsule every three days to a maximum of 8 capsules/day (4mg). Dosage will be maintained if higher doses are not tolerated or if sufficient relief is obtained (at least a 2-point change on the NRS). Once the appropriate nabilone (or placebo) dosage for each participant is determined, participants will begin their respective interventions over the course of the 4-week treatment period.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nabilone Capsules
Description: Capsules will be 0.5mg nabilone. Participants will undergo a 5-week titration period by taking 1 (0.5mg) nabilone capsule per day for a three-day period. The dose will be increased on a fixed schedule by 1 (0.5mg) capsule every three days to a maximum of 8 capsules/day (4mg). Dosage will be maintained if higher doses are not tolerated or if sufficient relief is obtained (at least a 2-point change on the NRS). Once the appropriate nabilone (or placebo) dosage for each participant is determined, participants will begin their respective interventions over the course of the 4-week treatment period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo capsules
Description: Placebo capsules contain no active ingredient. Participants on placebo capsules will undergo the same 5-week titration period and intervention period as those on active treatment.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsules
Description: Placebo capsules contain no active ingredient. Participants on placebo capsules will undergo the same 5-week titration period and intervention period as those on active treatment.