TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06704464

Intervention type: OTHER
Intervention: Manual Dexterity
Description: Individuals who meet the inclusion criteria will be evaluated for manual dexterity using MMDT, 9-HPT, ABILHAND, and JTHFT.

Intervention type: OTHER
Intervention: Manual Dexterity (only MMDT)
Description: Individuals who meet the inclusion criteria will be evaluated for manual dexterity using MMDT on a predetermined day.

Intervention type: OTHER
Intervention: disability level
Description: Individuals who meet the inclusion criteria will be evaluated for disability level using EDSS
Study: NCT05566769

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NMOSDCopilot smartphone application
Description: NMOSDCopilot includes active tests for walking, cognition, dexterity and vision, and e-questionnaires related to pain, fatigue, quality of life, bladder and bowel dysfunction, depression
Study: NCT05377814

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Volitional help sheet
Description: Participants are asked to choose from a list of strategies for increasing physical activity
Study: NCT05197270

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4D-150 IVT
Description: 4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Aflibercept IVT
Description: Commercially available Active Comparator Other Name: Eylea
Study: NCT05786196

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ab-interno canaloplasty utilizing the iTrack Advance device
Description: 360 degree microcatheterization and viscodilation of Schlemm's canal

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ab-interno canaloplasty utilizing the OMNI Surgical System
Description: 360 degree microcatheterization and viscodilation of Schlemm's canal
Study: NCT06538350

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telemedicine Consultation
Description: Telemedicine intervention will be delivered via Zoom and Video WhatsApp platforms via a secure internet connection.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Face-to-Face Consultation
Description: Face-to-Face consultation according to the standard of care.
Study: NCT05676450

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: cell-free DNA
Description: Given by IV (vein)
Study: NCT04938843

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: F. prausnitzii and D. piger
Description: Dietary supplementation with capsules containing F. prausnitzii and D. piger once daily for 12 consecutive weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Dietary supplementation with placebo capsules identical to those containing F. prausnitzii and D. piger once daily for 12 consecutive weeks
Study: NCT06417788

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dental implant placement
Description: Dental implant placement guided by Navident® (ClaroNav Inc., Toronto, Canada)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Static guided implant placement
Description: Dental implant placement guided by a stereolithographic pilot drill guide.
Study: NCT05544344

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy ReStart
Description: In addition to receiving mental health services as usual, subjects receive services from health coaches over a four-month period to assist them in creating a Restart plan and attaining related life goals.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Services as Usual
Description: Subjects receive mental health services as usual.
Study: NCT06220253

Intervention type: PROCEDURE
Group type: OTHER
Intervention: vaginal hysterectomy by bipolar vessels sealing
Description: The surgery will take place according to the canonical times of vaginal hysterectomy and all the support structures will be coagulated and cut by a bipolar vessel sealing instrument

Intervention type: PROCEDURE
Group type: OTHER
Intervention: vaginal hysterectomy by traditional technique
Description: The surgery will take place according to the canonical times of vaginal hysterectomy and all the support structures will be sutured by absorbable threads
Study: NCT06067139

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SHUTi
Description: Each core includes a variety of interactive features, such as animations, vignettes, myth and reality buttons that reveal common misperceptions and facts about sleep, learn more buttons that provide in-depth information about a topic, and quizzes. All cores follow a similar structure with objectives, main content, homework, and review. Participants are free to revisit cores as many times as they like.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Patient Education
Description: The PE website will present content in a simple, static form, without interactive components; and all content on the website will be provided at once, rather than in modules that unlock over time. The PE website will also not provide personalized or individually tailored treatment recommendations.
Study: NCT06398574

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real dry needling
Description: With the subject lying supine, a dry needling technique will be applied to the infraspinatus muscle. First, the most hyperalgesic point in the muscle will be located. Subsequently, Hong's fast-in and fast-out technique will be applied. Ten incisions will be made

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham dry needling
Description: With the subject lying supine, a sham dry needling technique will be applied to the infraspinatus muscle. First, the most hyperalgesic point in the muscle will be located. Subsequently, Hong's fast-in and fast-out technique will be applied. Ten incisions will be made, simulating the real technique
Study: NCT06133270

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0560-0004
Description: NNC0560-0004, Oral administration (taken through the mouth)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (NNC0560-0004)
Description: Placebo matching NNC0560-0004, Oral administration (taken through the mouth)
Study: NCT05313958

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cladribine
Description: 5mg/㎡/day d1-5 in 2 hours, before the use of Cytarabine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: G-CSF
Description: 5ug/kg/day d0-5,if Peripheral blood leukocytes\<20,000/ul

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: 2g/㎡/day d1-5 in 4 hours, after the use of Cladribine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Idarubicin
Description: Idarubicin 10mg/m2/day or mitoxantrone 10mg/m2/day on day 1-3 in the induction therapy II

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitoxantrone
Description: Idarubicin 10mg/m2/day or mitoxantrone 10mg/m2/day on day 1-3 in the induction therapy II

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sorafenib
Description: 200mg/m2/day was taken orally until molecular biology remission for 2 years
Study: NCT05601843

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Electrical Nerve Stimulation (TENS)
Description: TENS pads will be applied in a frame pattern around the area of maximal pain, as pointed out by the patient. The pads will be no more than 6 cm and no less than 3 cm away from the subjective area of maximal pain. The frequency of the TENS machine will be set to 100 Hz and the patient will be instructed on how to increase and decrease the amplitude based on their comfort. The patient will also be instructed on how to turn off the machine if they wish for any reason. Research assistants will be standing by during the intervention period to intervene if the patient requires assistance with the device.
Study: NCT06706726

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: sentinel lymph node biopsy
Description: sentinel lymph node biopsy during the management of breast cancer

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single-port robotic-assisted axillary lymph node dissection
Description: Single-port robotic-assisted（Endoscopic Instrument Control System SP1000) axillary lymph node dissection during the management of breast cancer
Study: NCT06707766

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oculomotor Exercise along with conventional Therapy
Description: Oculomotor Exercises: Saccadic eye movement, Smooth pursuit, Adaptation X1, Adaptation X2.~Time duration will be 2 minutes for each exercise.~conventional therapy: hot pack 20 mins Kendall exercises: Strengthening the deep cervical flexor, Stretching the cervical extensors, Strengthening shoulder retraction, Stretching of the pectoralis major muscle strengthening exercise: 12 repetitions\* 3 sets, 2-8 sec hold stretching exercise was: 3 reps\* 30 seconds' hold~Total duration of treatment would be 4 weeks, 3 days a week with total 12 sessions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sub-occipital muscle energy technique along with Conventional Therapy
Description: Sub-occipital muscle energy technique (PIR) 3 rep \* 1 set with 20 sec hold~conventional therapy: hot pack 20 mins Kendall exercises: Strengthening the deep cervical flexor, Stretching the cervical extensors, Strengthening shoulder retraction, Stretching of the pectoralis major muscle~strengthening exercise: 12 repetitions\* 3 sets, 2-8 sec hold stretching exercise was: 3 reps\* 30 seconds' hold~Total duration of treatment would be 4 weeks, 3 days a week with total 12 sessions.
Study: NCT06729190

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: biofeedback
Description: biofeedback therapy and FES at anti spastic muscles(shoulders flexors, elbow and wrist extensors) while doing specific exercises (including basic reaching, grasping, carrying, release

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Physical therapy program
Description: Flexibility exercises for shorted muscles and spastic muscles, Strengthening training focusing on the trunk lower limb and upper limb muscles for weak muscles, Postural control exercise in different positions and different surfaces, General endurance training, Exercises to facilitate hand function, Exercises included, grasping a cube, transferring cube, removing and placing pegs, releasing cube and placing cubes. Strengthening exercises of the intrinsic muscles of the hand

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Physical therapy program
Description: Flexibility exercises for shorted muscles and spastic muscles, Strengthening training focusing on the trunk lower limb and upper limb muscles for weak muscles, Postural control exercise in different positions and different surfaces, General endurance training, Exercises to facilitate hand function, Exercises included, grasping a cube, transferring cube, removing and placing pegs, releasing cube and placing cubes. Strengthening exercises of the intrinsic muscles of the hand
Study: NCT05576129

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TGP-tACS
Description: 38 min and 20s of 4mA peak-to-peak theta-gamma stimulation with 75 Hz-gamma coupled to the peak of 6Hz-theta waves. 3s ramp-up at the beginning of stimulation and 3s ramp-down at the end of stimulation.~Administered using a Starstim® device and 5 gel electrodes with a πcm² area.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham-tACS
Description: 38 min and 20s of alternation between 10s of 4mA peak-to-peak TGP- tACS and a 6 min 30s stimulation-free interval. Each stimulation consists of 3s ramp-up, 4s TGP stimulation and 3s ramp-down. Administered using a Starstim® device and 5 gel electrodes with a πcm² area.
Study: NCT04813042

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Working Out Dads
Description: The WOD is a manualised group intervention underpinned by solution-focused therapy and social cognitive theories. Psychoeducation about the transition to fatherhood and its potential impacts on wellbeing and family relationships is provided. Fathers are encouraged to share practical ideas for managing stress, revisit previous strategies, validate what they are doing well, and explore solutions.~The group discussion is followed by a structured group fitness session provided by a personal trainer. This session focuses on body weight exercises, cardio-based activities, stretching, mobility and incidental activity.~Fathers in the WOD study arm receive 10 weeks of encouraging text messages - one each week during the intervention, and four in the weeks after. These will be sent via the WhatsApp group created for each WOD group. These text messages and the WhatsApp group are designed to facilitate fathers' active engagement with the intervention, and to maintain contact with each other.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: The Usual Care arm, also known as 'Talking about being dad' comprises a telephone consultation with a qualified mental health professional. Topics including in this consultation include: (a) discuss family and fathering; (b) health and wellbeing; (c) mental health symptoms and conduct a risk assessment for suicidal ideation; (d) current supports and support needs; (e) provide referral options to telephone support services (PANDA; MensLine); and (f) encourage a general practitioner visit to discuss a mental health care plan.
Study: NCT04776213

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mavenclad®
Description: This low interventional extension study involves the follow up of participants in the parent study. The participants were followed up for an additional 2 year period (until 4 years after initial administration of Mavenclad® tablets), during which the participants were not treated with Mavenclad®, as per European Medicines Agency (EMA) label of Mavenclad®.
Study: NCT05646537

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neuro-Linguistic Programming Techniques
Description: The new behavior creation technique of NLP is based on the argument that the imagination process and reality are recorded in the same way in the brain.~Using the Participant's eye movements and imagination . He will be asked to imagine himself while caring for the stoma. participient will then be asked to re-enact the process with the correct stages of stoma care and the jurals that must be adhered to in order to successfully care for it.~Questions will be asked about where he can find the support he needs to carry out this process successfully. At the end of this whole process, he will be expected to construct what life is like with a stoma.The technique will be applied to the patient once and will be instructed to remember this successful process every time he or she feels distressed about the stoma.~At the end of 6 months, the quality of life and compliance will be evaluated by asking the scale questions again.
Study: NCT06179563

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: On-Demand Telemonitoring
Description: Patients assigned to the on-demand intervention group do not have to use the app at set time intervals but will be asked to use the app at their own discretion, in case of symptoms. This implies that patients have full control over their monitoring activities. Patients have the option to reach out to the hospital whenever they feel the need.
Study: NCT05611723

Intervention type: OTHER
Intervention: Exposure to disability
Description: Disability status assessed by functional measures
Study: NCT04959032

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lumateperone 42 mg
Description: Lumateperone 42 mg capsules administered orally, once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching capsules administered orally, once daily.
Study: NCT05533034

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: * 1 supervised session of rehabilitation, including a cardiac stress test (to define maximal intensity for aerobic activities), aerobic activity with interval training of moderate and progressive intensity (walking), and respiratory exercise using a volumetric spirometer, and strengthening exercises for lower and upper limbs.~* 3 months of self-managed home exercises. Patients will be asked to use a tracker activity when performing home exercises to self-monitor cardiac frequency and to assess their adherence.
Study: NCT06338410

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kangaroo Mother Care
Description: KMC is a care system for LBW and preterm infants at birth, based on skin-to-skin contact between the infant and the mother and exclusive breast feeding. The mother carries her Preterm infant for at least one hour per day. Urine collected before and after skin-to-skin contact.
Study: NCT06031337

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA
Description: quantitative determination of salivary SOX7 using an Enzyme Linked Immunosorbent assay (ELISA) kit based on the sandwich principle according to the manufacturer's protocol.

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA
Description: quantitative determination of salivary SOX7 using an Enzyme Linked Immunosorbent assay (ELISA) kit based on the sandwich principle according to the manufacturer's protocol.
Study: NCT06276621

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Bridge Program
Description: The Family Bridge Program consists of 7 components, delivered by a trained lay navigator, the Guide. The program includes: (1) orientation to the hospital, unit, room, and hospital resources (e.g., toiletries, loaner phone chargers); (2)unmet social needs assessment, followed by connection to appropriate resources (e.g., food vouchers, community-based transportation); (3)communication and cultural preference assessment (eg, preferred language, comfort asking questions, and health-related cultural beliefs), which is communicated to the medical team and documented in the electronic health record;(4)communication coaching for parents/caregivers to help them clarify and practice asking questions of the medical team; (5)emotional support via daily check-ins during the hospital stay; (6)assistance with logistics ; and (7)one follow-up phone call, 2 days post-discharge, to address remaining questions and connect families to ongoing services if needed.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Care as usual - resources only
Description: Families randomized to the control arm will receive FBP written resources, which the Guide (and interpreter, as needed) will review with them over \~5-15 minutes one time. This includes information on hospital services (e.g., cafeteria coupons), community resources (e.g., food and housing support), the structure and roles of the medical team, and the daily hospital schedule. Parents will be informed that their child's nurse is available to help them.
Study: NCT06300086

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Electronically delivered nudging letters to patients with CKD
Description: Patients in the active arm will receive a digital nudge letter as part of the study. The nudge letter will be delivered at baseline. Letters will be delivered through the official, mandatory Danish electronic letter system.~The control arm will consist of patients with CKD randomized to not receive digital nudge letters (usual care).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Electronically delivered nudging letters to patients with CKD
Description: Patients in the active arm will receive a digital nudge letter as part of the study. The nudge letter will be delivered at baseline. Letters will be delivered through the official, mandatory Danish electronic letter system.~The control arm will consist of patients with CKD randomized to not receive digital nudge letters (usual care).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Electronically delivered nudging letter to associated GPs of patients with CKD
Description: The associated GPs of the patients in the active arm will receive one digital nudge letter as part of the study. The nudge letter will be delivered at baseline. The letters will be delivered through the official, mandatory Danish electronic letter system.~The control arm will consist of patients with CKD whose associated GP was randomized to not receive a digital nudge letter (usual care).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Electronically delivered nudging letter to associated GPs of patients with CKD
Description: The associated GPs of the patients in the active arm will receive one digital nudge letter as part of the study. The nudge letter will be delivered at baseline. The letters will be delivered through the official, mandatory Danish electronic letter system.~The control arm will consist of patients with CKD whose associated GP was randomized to not receive a digital nudge letter (usual care).
Study: NCT05373043

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mitoquinone
Description: Mito-Q is a supplement that targets mitochondrial function. Linking a triphenyl-phosphonium cation to coenzyme-Q, to produce Mito-Q, results in a lipophilic compound, which, due to the large mitochondrial membrane potential, selectively accumulates within mitochondria. This targeted antioxidant approach results in 50- to 100-fold more Mito-Q accumulation compared to non-targeted antioxidant delivery.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Mitoquinone
Description: Mito-Q is a supplement that targets mitochondrial function. Linking a triphenyl-phosphonium cation to coenzyme-Q, to produce Mito-Q, results in a lipophilic compound, which, due to the large mitochondrial membrane potential, selectively accumulates within mitochondria. This targeted antioxidant approach results in 50- to 100-fold more Mito-Q accumulation compared to non-targeted antioxidant delivery.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A placebo will be used in combination with exercise rehabilitation allowing for a double blinded placebo controlled design.