TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06429124

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dietary Intervention
Description: Participants will be instructed to follow a 16/8 regimen characterized by 16 hours of fasting and an 8-hour eating window daily, on approximately 5 days/week, for 3 months. Previous research has shown that 16 hours of fasting is feasible, safe and well-tolerated among older adults, and that most persons report easy adjustment (Anton, Lee et al. 2019, Lee, Sypniewski et al. 2020). The intervention will be implemented through individual and group sessions with participants and will involve extensive education, coaching, guidance, and support throughout the 3-month intervention. Educational materials on lifestyle factors including physical activity will be provided to each participant. We will be also be collecting data on physical activity and sedentary behavior. These data will be co-variates when we conduct the statistical analysis.
Study: NCT05335265

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment training
Description: Face-to-face:Metered-DoseInhalerTraining gave 3 times on the 1st day, 2 times on the 2nd day, once on the 3rd day.During discharge, inhaler technical evaluation were done according to the Application Steps of Inhalation Techniques Evaluation Form checklist prepared by using the Patient's Booklet of the Turkish Thoracic Society (TTS).The people who is evaluate the patient's inhaler technique (IT) on the day of discharge was someone different from the health personnel who provided the training. In IT control, the patient's performance was evaluated simultaneously by 2 observers.~Video training:Training gave 3 times on the 1st day, 2 times on the 2nd day,once on the 3rd day.The TTS-Virtual Training Video were used.During discharge,inhaler technical evaluation was done same with face-to-face training.The person who is evaluate the patient's IT was someone different from the training personnel.In IT observation,it was used same method with face-to-face training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment training
Description: Face-to-face:Metered-DoseInhalerTraining gave 3 times on the 1st day, 2 times on the 2nd day, once on the 3rd day.During discharge, inhaler technical evaluation were done according to the Application Steps of Inhalation Techniques Evaluation Form checklist prepared by using the Patient's Booklet of the Turkish Thoracic Society (TTS).The people who is evaluate the patient's inhaler technique (IT) on the day of discharge was someone different from the health personnel who provided the training. In IT control, the patient's performance was evaluated simultaneously by 2 observers.~Video training:Training gave 3 times on the 1st day, 2 times on the 2nd day,once on the 3rd day.The TTS-Virtual Training Video were used.During discharge,inhaler technical evaluation was done same with face-to-face training.The person who is evaluate the patient's IT was someone different from the training personnel.In IT observation,it was used same method with face-to-face training.
Study: NCT05897502

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: multimedia education
Description: The experimental group use multimedia education, 20 minute nutrition education courses each time, a total of 8 courses.~The control group use routine education.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: multimedia education
Description: The experimental group use multimedia education, 20 minute nutrition education courses each time, a total of 8 courses.~The control group use routine education.
Study: NCT06134895

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tramadol with Ketamine
Description: Tramadol with Ketamine is being provided randomly using prospective, double-blind

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol
Description: Tramadol alone is being provided randomly using prospective, double-blind
Study: NCT05463705

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention to address diffusion of responsibility
Description: PCPs will receive an email from a peer offering encouragement and support in prescribing SGLT-2is and GLP-1RAs that includes specific components designed to reduce diffusion of responsibility. Specifically, these elements will be adapted from interventions that mitigate diffusion of responsibility in other contexts, including: (1) assigning responsibility to individuals or smaller groups, (2) increased perceived harm of the situation to be addressed (3) highlighting competence to act, and (4) modeling the desired behavior. The email will also contain a link to clinical and administrative information to support prescribing and an offer for direct support from the peer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention to address diffusion of responsibility + simplification of prescribing
Description: PCPs will receive the same contact addressing diffusion of responsibility as in the Intervention to address diffusion of responsibility arm, but will additionally have access to an experienced administrative team for diabetes medication insurance authorization support, by routing their clinic note through the EHR. PCPs will be informed, suing the same email outreach, how to access the administrative team, which consists of medical and administrative assistants and currently supports prescribing within the endocrinology division. The team will follow up with the pharmacy to determine coverage, complete prior authorizations, determine alternate covered options, and track progress.
Study: NCT06217185

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib
Description: Pyrotinib 400mg qd po continuously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: For Trastuzumab, the loading dose for the first treatment cycle is 8 mg/kg, and for subsequent cycles, 6 mg/kg. It is to be used once every three weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Taxanes
Description: Taxanes: Usual clinical dose is administered, in a 21-day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine: 650mg/m2 each time, given twice daily
Study: NCT04008563

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bariatric Surgery
Description: Patients who are randomized to the intervention group will receive a progestin intrauterine device and be referred for bariatric service to undergo bariatric surgery within 3 months of their study consent.
Study: NCT05757960

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Physiotherapy
Description: Various physiotherapeutic techniques are used in three defined sessions. Before the first session, a dental examination is performed and a clinical functional status is obtained to assess the extent of temporomandibular dysfunction. The results are recorded on validated questionnaires.
Study: NCT04911218

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GlideSheath Slender 5Fr arterial sheath
Description: Placement of GlideSheath Slender 5Fr arterial sheath for coronary angiography through the distal radial artery (anatomical snuffbox).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional 5Fr arterial sheath
Description: Placement of conventional 5Fr arterial sheath for coronary angiography through the distal radial artery (anatomical snuffbox).
Study: NCT04879537

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Telemedical support
Description: The nursing homes participating in the project will be equipped with telemedical equipment. This will allow teleconsultations to take place when needed. In addition, an early warning system will be introduced and, within the framework of the teleconsultation, a trained medical assistant can be sent to the care facility if necessary, who can carry out medical activities on site under a physician's delegated instructions. In addition, an electronic patient file will be introduced which can be accessed by the telemedicine physician and the general practitioner.
Study: NCT04903379

Intervention type: OTHER
Group type: OTHER
Intervention: Education
Description: An explanation of contemporary pain science and a description of effective treatment strategies used by people with a history of persistent pain.
Study: NCT06511726

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: Induction chemotherapy and immunotherapy: Cadonilimab + cisplatin + albumin-bound paclitaxel, for a total of 2 cycles (cisplatin 75 mg/m² + albumin-bound paclitaxel 260 mg/m² q3w, Cadonilimab 10 mg/kg q3w).
Study: NCT06466213

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: single exercise bout about one-leg exercise
Description: cycle exercise includes single leg
Study: NCT05191680

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apalutamide Oral Tablet [Erleada]
Description: Apalutamide is a selective Androgen Receptor (AR) inhibitor that binds directly to the ligand-binding domain of the AR.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apalutamide Oral Tablet [Erleada]
Description: Apalutamide is a selective Androgen Receptor (AR) inhibitor that binds directly to the ligand-binding domain of the AR.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match apalutamide
Study: NCT04778501

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IOL implantation experimental
Description: Mono- or bilateral implantation of toric intraocular lenses PODEYE TORIC. If only one eye qualifies for toric lens implantation due to small amount of pre-existing corneal astigmatism, one eye will be implanted with PODEYE TORIC and the contralateral eye will be receive an implantation with the monofocal parent lens PODEYE (PhysIOL sa/nv, Liège, Belgium).
Study: NCT05617092

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy treatment
Description: physiotherapy individualized treatment according to the needs of the patient and clinical findings and symptoms
Study: NCT05767957

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation physiotherapy
Description: Rehabilitation physiotherapy by physiotherapist using conventional technique alone.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive-behavioral therapies in addition to rehabilitation physiotherapy
Description: Rehabilitation physiotherapy by physiotherapist according to conventional technique, with the addition of techniques from cognitive-behavioral therapies.
Study: NCT06407362

Intervention type: DIAGNOSTIC_TEST
Intervention: Cerebral Oxygen Saturation
Description: We have designed this study to evaluate the accuracy of PVI, PI and rSO2 in both ventilation modes in patients undergoing septorhinoplasty operation under general anaesthesia
Study: NCT06077422

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bupivacaine liposome injectable suspension
Description: Bupivacaine liposome injectable suspension (Exparel) will be administered by ultrasound-guided ESP block, unilaterally if thoracotomy on ipsilateral side, bilaterally if median sternotomy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: Bupivacaine HCl (Marcaine) will be administered by ultrasound-guided ESP block, unilaterally if thoracotomy on ipsilateral side, bilaterally if median sternotomy.
Study: NCT01549847

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-carnitine and piracetam
Description: L-carnitine/piracetam (990mg/810mg) PO BID

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo PO BID
Study: NCT05205707

Intervention type: DIAGNOSTIC_TEST
Intervention: ACE serum levels
Description: Circulating ACE2 level will be measured

Intervention type: DIAGNOSTIC_TEST
Intervention: ACE serum levels
Description: Circulating ACE2 level will be measured
Study: NCT06065722

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Akynzeo
Description: OLANZAPINE

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Akynzeo
Description: OLANZAPINE
Study: NCT06092060

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: the group GS (probiotic)
Description: The probiotic-supplemented group will receive 2 capsules of freeze-dried powder of a probiotic mixture containing the following bacterial strains twice a day, 3-month: Bifidobacterium lactis W52, Lactobacillus brevis W63, Lactobacillus casei W56, Lactococcus lactis W19, Lactococcus lactis W58, Lactobacillus acidophilus W37, Bifidobacterium bifidum W23, Bifidobacterium lactis W51, Lactobacillus salivarius W24

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: the group GP (placebo)
Description: The placebo group will receive 2 capsules consisting of the probiotic product carrier, which is corn starch and maltodextrin, twice a day, 3-month.
Study: NCT06057155

Intervention type: DIAGNOSTIC_TEST
Intervention: ultrasound optic nerve sheath diameter assessment
Description: ultrasound optic nerve sheath diameter assessment
Study: NCT06450951

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Urinary EDC metabolite testing
Description: Mail-in urine samples tested for metabolites of bisphenols, phthalates, parabens, and oxybenzone.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Urinary EDC metabolite testing
Description: Mail-in urine samples tested for metabolites of bisphenols, phthalates, parabens, and oxybenzone.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational curriculum
Description: A self-directed online interactive curriculum of EDC material, with access to live coaches and an online forum.
Study: NCT05492162

Intervention type: OTHER
Group type: OTHER
Intervention: well-being promotion intervention
Description: The intervention will be organized on both conferences and workshops.~Four themes will be covered :~* Well-being (Workshops)~* Smoking prevention (Conference)~* Balanced diet (Workshop)~* Optimal organization for daily healthy living (Conference)
Study: NCT06133101

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard Soy Milk
Description: Consumption of commercially available soy milk

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 2% Fat Cow's Milk
Description: Consumption of commercially available 2% cow's milk
Study: NCT05301218

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: angioplasty
Description: Coronary angioplasty, also called percutaneous coronary intervention, is a procedure used to open clogged heart arteries. Angioplasty uses a tiny balloon catheter that is inserted in a blocked blood vessel to help widen it and improve blood flow to the heart
Study: NCT06087510

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: Different doses of esketamine in the esketamine-dexmedetomidine combination as a supplement to sufentanil for postoperative analgesia.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Esketamine
Description: Different doses of esketamine in the esketamine-dexmedetomidine combination as a supplement to sufentanil for postoperative analgesia.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: Different doses of esketamine in the esketamine-dexmedetomidine combination as a supplement to sufentanil for postoperative analgesia.
Study: NCT05301218

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: angioplasty
Description: Coronary angioplasty, also called percutaneous coronary intervention, is a procedure used to open clogged heart arteries. Angioplasty uses a tiny balloon catheter that is inserted in a blocked blood vessel to help widen it and improve blood flow to the heart
Study: NCT04627857

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual toothbrush
Description: Patients in group 1 (''reference procedure'') receive a manual toothbrush with a small compact head to facilitate access to the posterior teeth and soft bristles.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Manual toothbrush and water flosser (Philips Sonicare AirFloss)
Description: - Group 2 patients receive a manual toothbrush with a small, compact head for easy access to the posterior teeth and soft bristles. They also receive a Philips brand interdental microjet (Philips Sonicare AirFloss Ultra) which must be filled with water.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sonic toothbrush
Description: - Group 3 patients receive a rechargeable sonic electric toothbrush from Philipps with an integrated excess pressure sensor and a compact toothbrush head for easy access to the posterior teeth.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sonic toothbrush (Philips Sonicare) and water flosser (Philips Sonicare AirFloss)
Description: - Group 4 patients receive a Philips Sonicare ProtectiveClean rechargeable sonic electric toothbrush with an integrated excess pressure sensor and 2 compact toothbrush heads for easy access to the posterior teeth. They also receive an interdental microjet from Philips (Philips Sonicare AirFloss Ultra) which must be filled with water.
Study: NCT06596226

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pathways Parent Mediated Intervention
Description: Pathways-trained research clinicians will conduct 90-minute weekly coaching sessions with caregivers in the family's home or other convenient location. Caregivers will receive a written version of the program manual. Sessions will review information about social communication, infusing mutual gaze in social sensory routines, and using naturalistic developmental behavioral strategies. Interventionists will demonstrate intervention strategies and provide caregivers with practice feedback and self-reflection.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pathways Parent Mediated Intervention without Mutual Gaze
Description: Pathways-trained research clinicians will conduct 90-minute weekly coaching sessions with caregivers in the family's home or other convenient location. Caregivers will receive a written version of the program manual. Sessions will review information about social communication, social sensory routines, and naturalistic developmental behavioral strategies described in the program manual. Interventionists will demonstrate intervention strategies and provide caregivers with practice feedback and self-reflection.
Study: NCT06606262

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tonsillotomy
Description: Bilateral partial removal of the palatine tonsils to a level between the pharyngeal pillars and the tonsillar capsule. Surgery will be performed under general anesthesia using monopolar electrocautery.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tonsillectomy
Description: Bilateral extracapsular removal of palatine tonsils. Surgery will be performed under general anesthesia using cold knife dissection.
Study: NCT06597695

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine-assisted psychotherapy
Description: Ketamine-assisted psychotherapy delivered in a group format
Study: NCT06618339

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Mindfulness-based intervention
Description: 8 Session Mindfulness-based intervention

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Mindfulness-based intervention
Description: 8 Session Mindfulness-based intervention
Study: NCT06623162

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gemcitabine + cisplatine
Description: 4 cycles
Study: NCT06622239

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone
Description: naltrexone 50mg for 6 weeks
Study: NCT05111275

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive exercises
Description: Exercises that stimulate and train memory, attention, executive functions, language and gnosis.
Study: NCT06622239

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo for 6 weeks
Study: NCT06624735

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: psychometry
Description: ADHD test and measurement of IQ level

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: psychometry
Description: ADHD test and measurement of IQ level
Study: NCT05917522

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Abatacept
Description: Injection: 125 mg/mL of a clear to slightly opalescent, colorless to pale-yellow solution in a single-dose prefilled ClickJect autoinjector

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care at US Transplant Centers
Description: Control group, remaining on SOC (Tacrolimus/ Mycophenolic Acid (MPA)/ Prednisone (Pred))
Study: NCT05196347

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: In dapagliflozin arm, subjects will be received dapagliflozin 5 mg for 4 weeks. Uptitration to 10 mg will be done between 5 to 12th weeks, if eGFR dip \<20%.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin
Description: In dapagliflozin arm, subjects will be received dapagliflozin 5 mg for 4 weeks. Uptitration to 10 mg will be done between 5 to 12th weeks, if eGFR dip \<20%.
Study: NCT04741477

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD
Description: CBD will be topically applied

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC
Description: THC will be topically applied

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: a placebo product (without cannabinoids) will be topically applied
Study: NCT05812118

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical active learning
Description: The intervention will last for 8-10 weeks. The ALPHYL intervention will be conducted in physical education (PE) and non-PE lessons by teachers. In addition to the PE lessons, at least three physically active activities in subjects other than PE will be conducted every day (5 days per week), with a total duration of approximately 30 minutes of light and moderate-to-vigorous physical activity per day. The weekly dose of physically active learning will thus be 100-150 minutes, so that a volume of 800-1200 minutes is foreseen during the 8-10 weeks. The PE classes will also be conducted in a mix of cooperative learning, non-linear pedagogy and health-based PE.
Study: NCT05748561

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant human erythropoietin 4,000 UI and 2,000 UI
Description: Intravenous recombinant human erythropoietin (10,000 IU every 24 hours for 5 days)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methylprednisolone succinate 500 mg
Description: Intravenous Methylprednisolone succinate (1 g daily for 5 days)
Study: NCT05312983

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audiological and vestibular tests
Description: 6h of audiological and vestibular tests divide in 3 sessions :~* Session A : objective audiological tests~* Session B ; subjective audiological tests~* Session C : balance tests.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: A 10 mL blood sample will be collected during the study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: neurocognitive self-questionnaire
Description: Four self-questionnaires to fill out to measure sleep quality, memory and emotional state