Study: NCT05708885

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction
Description: To reduce the laryngeal movement and St.Eso excursion we will use a device constructed in our laboratory which can induce an adjustable resistance to excursion of the larynx. This handmade device that is worn around the neck consists of a band and a concave plastic disk which serves as a support structure for an inflatable polyethylene bag which is connected to a hand pump and pressure gauge. When worn around the neck the inflatable bag rests in position on the thyroid cartilage with a portion of it hung over above the cartilage creating resistance to its superior excursion when fixed by closure straps. A known external force may be applied to the thyroid by partially inflating the bag to a specific pressure reading on the gauge. The soft and compliant bag conforms to the larynx while applying a resistive force to anterior and superior distraction of the hyolaryngeal complex during swallowing.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction
Description: To reduce the laryngeal movement and St.Eso excursion we will use a device constructed in our laboratory which can induce an adjustable resistance to excursion of the larynx. This handmade device that is worn around the neck consists of a band and a concave plastic disk which serves as a support structure for an inflatable polyethylene bag which is connected to a hand pump and pressure gauge. When worn around the neck the inflatable bag rests in position on the thyroid cartilage with a portion of it hung over above the cartilage creating resistance to its superior excursion when fixed by closure straps. A known external force may be applied to the thyroid by partially inflating the bag to a specific pressure reading on the gauge. The soft and compliant bag conforms to the larynx while applying a resistive force to anterior and superior distraction of the hyolaryngeal complex during swallowing.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction
Description: To reduce the laryngeal movement and St.Eso excursion we will use a device constructed in our laboratory which can induce an adjustable resistance to excursion of the larynx. This handmade device that is worn around the neck consists of a band and a concave plastic disk which serves as a support structure for an inflatable polyethylene bag which is connected to a hand pump and pressure gauge. When worn around the neck the inflatable bag rests in position on the thyroid cartilage with a portion of it hung over above the cartilage creating resistance to its superior excursion when fixed by closure straps. A known external force may be applied to the thyroid by partially inflating the bag to a specific pressure reading on the gauge. The soft and compliant bag conforms to the larynx while applying a resistive force to anterior and superior distraction of the hyolaryngeal complex during swallowing.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Description: Use the previously mentioned wearable device (sRED) and exercise regimen described previously for studying the effect of increase in anterosuperior excursion of the larynx/St.Eso on St.Eso peristaltic function.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Description: Use the previously mentioned wearable device (sRED) and exercise regimen described previously for studying the effect of increase in anterosuperior excursion of the larynx/St.Eso on St.Eso peristaltic function.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Description: Use the previously mentioned wearable device (sRED) and exercise regimen described previously for studying the effect of increase in anterosuperior excursion of the larynx/St.Eso on St.Eso peristaltic function.