TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05173610

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation: Stereotactic body radiotherapy (SBRT)
Description: Patients will be treated with stereotactic body radiotherapy (SBRT) for oligometastasis from hepatocellular carcinoma.~1. Target delineation The GTV is set using diagnostic CT, MRI, PET-CT, etc. CTV is delineated including the microscopic range in GTV and internal margin using 4D-CT. The PTV is expanded by considering the uncertainty of the daily patient posture setting and placement.~2. Radiotherapy All patients are treated using 3D-CRT, IMRT, or VMAT. Total dose and fractionations will be determined depending on the location and character of the metastasized tumor. Detailed radiation prescriptions is summarized in the following paragraph.~   i. Liver: 48-60 Gy in 4 fractions ii. Lung: 45-60 Gy in 3-4 fractions iii. Brain: 27-30 Gy in 3-5 fractions iv. bone: 24-40 Gy in 3-5 fractions v. adrenal gland: 30-60 Gy in 3-8 fractions vi. other organ: depending on the clinicians' decision
Study: NCT04994873

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STEP
Description: Behavioral intervention to increase positive affect

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced TAU
Description: Standard care plus a phone app with a personalized safety plan
Study: NCT03276052

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aclidinium Bromide 400 μg
Description: Aclidinium Bromide 400 μg BID inhalation powder. One oral inhalation via Genuair® dry powder inhaler (DPI)
Study: NCT05489653

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mixed music
Description: Learn about the effects of listening to music and doing activities with it on sleep.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: mixed music
Description: Learn about the effects of listening to music and doing activities with it on sleep.
Study: NCT03402789

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docosahexaenoic Acid
Description: Docosahexaenoic acid 1,200mg daily plus 2 hours of eye patching daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral Tablet
Description: Placebo tablet daily plus 2 hours of eye patching daily
Study: NCT06059521

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Software refraction with Eye Test Technology in a mobilerone
Description: Refraction is done by software App by a mobilerone software installed.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Retinoscopy
Description: Retinoscopy is an objective refraction method with retinoscope.
Study: NCT05462977

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group exercise program
Description: Participants will be asked to join a music-based group exercise program for 24 weeks (up to 6 days/week, 30 - 45 min/day), which is designed for older adults with functional limitations to safely exercise on a chair or in a supported standing posture for the improvement of aerobic capacity, upper and lower body strength, and balance control at a gradually increasing pace in synchrony with music.
Study: NCT05004038

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: BCG Vaccine AJVaccines
Description: Single intradermal injection of BCG Vaccine according to published Summary of Product Characteristics

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: BCG Vaccine AJVaccines
Description: Single intradermal injection of BCG Vaccine according to published Summary of Product Characteristics
Study: NCT06284993

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: electroacupuncture(more frequent)
Description: With the patient in a prone position, the local skin will be routinely sterilized, Ashi points will be perpendicularly inserted into the plantar fascia layer with a depth of approximately 15-20 mm depending on the location. BL57, KI3, and BL60 will be punched perpendicularly 10-15 mm deep into the skin. All needles except the Ashi points will be manually stimulated with small, equal manipulations of lifting, thrusting, twirling, and rotating to achieve De qi (a sensation including soreness, numbness, distention, and heaviness), and the practitioner has a feeling of needle sinking and tightness. The electroacupuncture instrument is connected to the needle handle of BL57 and BL60 respectively. During the needle retention period, except for BL57 and BL60, which are connected to the electroacupuncture instrument, Ashi points and KI3 perform a small and uniform twisting technique three times every 10 min, and a total of 3 times within 30min.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: electroacupuncture(less frequent)
Description: The intervention is the same as Group M except that the frequency of acupuncture will be once per week acupuncture. During the treatment period, in addition to acupuncture, patients will be visited twice a week for a total of 8 visits by telephone or in person. If the content of the visit aligns with the established efficacy evaluation visit in the program, it will be carried out as planned. If not, the patient will be inquired about the progress of their condition since the previous treatment, any rescue medication taken, and other relevant information. Visits that do not involve improvement in relevant indicators of study concern do not need to be recorded.~The electroacupuncture will last for 30 min and will be performed three sessions per week or one session per week for a total of 12 or 4 sessions in four consecutive weeks. Participants in both groups will be treated and (or) evaluated separately.
Study: NCT05706142

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imagery Education
Description: Within the scope of motor imagery training, a presentation will be made to the students of pediatric rehabilitation lecture in the intervention group about what motor imagery is. PETTLEP model will be used for imagery training. In this model, imagery training will be prepared in accordance with our purpose, taking into account the physical, environmental, time, task, learning, emotion and personal subheadings. In the training sessions, relaxation exercises will be given for 5 minutes first. After the relaxation exercises, special colic massage imagery training will be given to newborns for 10 minutes. The massage will also be shown as practically at class.
Study: NCT06061289

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: SP Detox Program
Description: The production use and disposal of toxic chemicals and synthetic materials have increased the risk of exposure to health-threatening toxins. Causal relationships between toxic chemicals and diseases have been well established. However, many patients endure chronic symptoms that are associated with exposure to toxins before advanced stages of specific diseases are realized. Thus, there is a great demand for noninvasive laboratory tests that can provide timely assessment of chemical exposure and the capability of hepatic detoxification
Study: NCT05517213

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Chemotherapy combined with rhG-CSF is widely used in autologous hematopoietic stem cell mobilization programs. For patients who do not meet the criteria of stem cell collection, they can be mobilized again after 1 month of rest. Chemotherapy +rhG-CSF mobilization or rhG-CSF+ ploxafo steady-state mobilization can be used.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Chemotherapy combined with rhG-CSF is widely used in autologous hematopoietic stem cell mobilization programs. For patients who do not meet the criteria of stem cell collection, they can be mobilized again after 1 month of rest. Chemotherapy +rhG-CSF mobilization or rhG-CSF+ ploxafo steady-state mobilization can be used.
Study: NCT05615831

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance Training with Blood flow restriction
Description: Participants will perform six weeks of blood flow restriction (60% occlusion) combined with resistance training at 30% of 1RM. The intervention comprises five exercises: incline chest press, seated row, leg press, knee extension, and knee flexion. The protocol is as follows: 30 repetitions followed by three sets of 15 repetitions for a total of four sets and 75 repetitions per exercise. There will be a one-minute recovery between sets where the cuffs remain inflated and a four-minute recovery between exercises where the cuffs will be deflated.
Study: NCT06346366

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bihormonal artificial pancreas (BIHAP) / closed loop
Description: The investigational device is a dual-hormonal fully closed loop system (BIHAP; industrial name AP® 5, Inreda Diabetic B.V.) which aims at optimally controlling plasma glucose levels. This BIHAP contains of two pumps for subcutaneous infusion of either insulin (Humalog, 3 ml pre-fill cartridge, Eli Lilly) or glucagon (GlucaGen, Novo Nordisk; 3.15 ml cartridge Accu-Chek Spirit, Roche) via an infusion set (Accu-Chek Insight Flex or AccuChek Flex Link, Roche), two subcutaneously placed glucose-sensors (Guardian, Medtronic) and an algorithm driving pump infusion rates based on the sensor input. Daily self-measurements of blood glucose (SMBGs; Accu-Chek Instant, Roche) are needed for calibration of the glucose sensors.~The BIHAP-system has to be worn continuously, except while showering.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bihormonal artificial pancreas (BIHAP) / closed loop
Description: The investigational device is a dual-hormonal fully closed loop system (BIHAP; industrial name AP® 5, Inreda Diabetic B.V.) which aims at optimally controlling plasma glucose levels. This BIHAP contains of two pumps for subcutaneous infusion of either insulin (Humalog, 3 ml pre-fill cartridge, Eli Lilly) or glucagon (GlucaGen, Novo Nordisk; 3.15 ml cartridge Accu-Chek Spirit, Roche) via an infusion set (Accu-Chek Insight Flex or AccuChek Flex Link, Roche), two subcutaneously placed glucose-sensors (Guardian, Medtronic) and an algorithm driving pump infusion rates based on the sensor input. Daily self-measurements of blood glucose (SMBGs; Accu-Chek Instant, Roche) are needed for calibration of the glucose sensors.~The BIHAP-system has to be worn continuously, except while showering.
Study: NCT05615337

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MBSR
Description: The MBSR is an eight-week group-based psychoeducational program. It is performed in weekly group sessions with the duration of 2.5 hours and a half-day retreat of 4 hours.~The program involves focused attention, consisting of body scan, yoga, and meditation. This program trains participants to be attentive to their thoughts, emotions, and sensations. There are also discussions on relevant topics related to the physiology of stress and strategies of coping. Materials for home practice are provided.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HPP
Description: The HPP has the same structure of MBSR, including different components such as music, nutrition, cognitive enhancement, risk factors for dementia, and physical activity. During the half-day retreat participants are involved in watercolor painting activities. Materials for home practice are also provided.
Study: NCT04949568

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Self-Management Behaviors
Description: The intervention is to be delivered by a diabetes educator.
Study: NCT05244460

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Droperidol Injectable Product
Description: Treatment
Study: NCT05075200

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: Participants in both groups will be given single intravenous bolus of TXA 20 mg/kg over 15 min after induction of spinal (or other regional technique) or general anesthesia as per standard of care.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: Participants in both groups will be given single intravenous bolus of TXA 20 mg/kg over 15 min after induction of spinal (or other regional technique) or general anesthesia as per standard of care.
Study: NCT04118140

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Somatic Acupressure
Description: 7-week self-acupressure plus usual care (an education booklet)

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham acupressure
Description: Same dose as the true acupressure group but on the sham acupoints plus usual care (an education booklet)

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Usual care
Description: Usual care only (an education booklet)
Study: NCT05244460

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diphenhydramine
Description: Treatment
Study: NCT04615260

Intervention type: DEVICE
Group type: OTHER
Intervention: NanoBone
Description: Nanobone® Synthetic Bone Graft is a nanocrystalline hydroxyapatite imbedded in a silica gel matrix. The nanocrystalline structure accurately replicates autologous hydroxyapatite and the silica gel matrix that rapidly transforms into an osteogenic matrix post-implantation. NanoBone promotes remodeling by acting as a strong osteoinductive material. NanoBone® is available as a putty.
Study: NCT04118140

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care only (an education booklet)

Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: Usual care only (an education booklet)
Study: NCT06289088

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: First Intervention
Description: Firstly, For individuals with low back pain, all measurements will be evaluated without wearing any orthosis. The waist circumference of individuals with low back pain will be measured and the orthosis was adapted to the appropriate orthosis size by the prosthetist orthotist. After waiting with the orthosis for half an hour, the measurements will be repeated. Then, the person will be asked to wear the orthosis without any intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Second Intervention
Description: Firstly, The waist circumference of individuals with low back pain will be measured and the orthosis will be adapted to the appropriate orthosis size by the prosthetist orthotist. After waiting with the orthosis for half an hour, the person will be asked to wear the orthosis without any intervention and the outcome measurements will be repeated. After waiting with the orthosis for half an hour, all measurements will be evaluated without wearing any orthosis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Third Intervention
Description: Firstly, the person will be asked to wear the orthosis without any intervention and the outcome measurements will be done. The waist circumference of individuals with low back pain will be measured and the orthosis will be adapted to the appropriate orthosis size by the prosthetist orthotist. After waiting with the orthosis for half an hour, all measurements will be evaluated without wearing any orthosis. Lastly, The waist circumference of individuals with low back pain will be measured and the orthosis will be adapted to the appropriate orthosis size by the prosthetist orthotis. After waiting with the orthosis for half an hour, all measurements will be evaluated.
Study: NCT04947878

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prompt list
Description: The patients in the intervention group will review a prompt list before their visit.
Study: NCT04525989

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiation therapy
Description: 5 x 5 Gy external radiation therapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation therapy
Description: 5 x 5 Gy external radiation therapy
Study: NCT05703620

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Renal Denervation
Description: All eligible participants receive ultrasound based renal denervation to both kidneys on all eligible vessels

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Renal Denervation
Description: All eligible participants receive ultrasound based renal denervation to both kidneys on all eligible vessels

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Renal Denervation
Description: All eligible participants receive ultrasound based renal denervation to both kidneys on all eligible vessels
Study: NCT05497622

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Quantitative Ultrasound
Description: Ultrasound assessment of Trapezius muscle

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Quantitative Ultrasound
Description: Ultrasound assessment of Trapezius muscle

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Osteopathic TART Assessment
Description: Evaluation of the 4 diagnostic criteria:~1. Tissue Texture abnormality~2. Asymmetry~3. Restriction of Motion~4. Tenderness

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Osteopathic TART Assessment
Description: Evaluation of the 4 diagnostic criteria:~1. Tissue Texture abnormality~2. Asymmetry~3. Restriction of Motion~4. Tenderness

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulation Treatment
Description: Use of manual techniques such as soft tissue stretching, resisted isometric stretches, fascial relaxation and counter strain.
Study: NCT04676308

Intervention type: OTHER
Intervention: Artificial Intelligence
Description: Artificial intelligence

Intervention type: OTHER
Intervention: Artificial Intelligence
Description: Artificial intelligence
Study: NCT05128162

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Two oral doses of psilocybin in a capsule formulation taken approximately 2 weeks apart.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychotherapy
Description: 1. Pre-dose preparatory sessions; 2. Dosing day monitoring; and, 3. Post-dose integration sessions.
Study: NCT05615987

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Onabotulinumtoxina for Injection
Description: 200iu/2ml in both groups

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Onabotulinumtoxina for Injection
Description: 200iu/2ml in both groups
Study: NCT04677426

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyperpolarized Xe129
Description: Whether magnetic resonance imaging (MRI) using inhaled hyper-polarized 129 Xenon gas can help visualize impaired lung function to assess patients with cHP and IPF.
Study: NCT05995730

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lavender oil inhalation
Description: Lavender inhalation will be administered to this group. Participants will be asked to drop three drops of lavender oil solution on a small piece of cotton on the 1st, 2nd, and 3rd days of their first menstrual bleeding after enrollment in the study, hold it 7-10 cm from their noses, and sniff for 5 minutes. Participants will be asked to apply this application immediately after the onset of dysmenorrhea pain on the first day of their menstruation and to continue regularly every 8 hours for the first three days of menstrual bleeding. Participants will be asked to apply this application in the same way in two consecutive menstrual cycles and the participants will be followed in this process.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Olive oil will be administered to the placebo group. The application will be similar to the experimental group.
Study: NCT06461585

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sprint interval training
Description: Group A the Interventional group will receive SIT . Group A will perform SIT 3 times a week for 30-second sprints on a cycle ergometer with 4 minutes of rest between each sprint, complete session will be for 30 -40 minutes. Group B will receive the aerobic exercise. Group B will perform the aerobic exercise for 30-40 minutes of moderate-intensity continuous exercise on a treadmill and stationary cycle

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sprint interval training
Description: Group A the Interventional group will receive SIT . Group A will perform SIT 3 times a week for 30-second sprints on a cycle ergometer with 4 minutes of rest between each sprint, complete session will be for 30 -40 minutes. Group B will receive the aerobic exercise. Group B will perform the aerobic exercise for 30-40 minutes of moderate-intensity continuous exercise on a treadmill and stationary cycle
Study: NCT05149950

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active internet treatment
Description: The patient gets access to the internet treatment via a secure login to 1177 The care guide e-services on 1177.se. The treatment lasts for six months and includes 12 treatment modules. The patient works with each module for two weeks. The modules have different numbers of sections, but most have 4-5 sections. The modules consist mainly of text but also films and pictures are included. It is also possible to listen to the text. The modules end with one or more exercises to be performed before the next module is activated for the patient. Participants receive feedback on the information from therapists via the email function in the treatment program. The therapist provides individual feedback on completed exercises and answers questions that the patient has.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Active internet treatment
Description: The patient gets access to the internet treatment via a secure login to 1177 The care guide e-services on 1177.se. The treatment lasts for six months and includes 12 treatment modules. The patient works with each module for two weeks. The modules have different numbers of sections, but most have 4-5 sections. The modules consist mainly of text but also films and pictures are included. It is also possible to listen to the text. The modules end with one or more exercises to be performed before the next module is activated for the patient. Participants receive feedback on the information from therapists via the email function in the treatment program. The therapist provides individual feedback on completed exercises and answers questions that the patient has.
Study: NCT06002867

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SAPB (Serratus Anterior Plan) Block
Description: The patient will be in the supine position. The area where the procedure will be performed will be cleaned with povidone iodine. Using a 22-gauge, 80 mm insulated Quincke needle with a high frequency (10-18 MHz) ultrasound linear probe covered with a sterile sheath, the latissimus dorsi muscle and the serratus muscle will be visualized at the level of the 4th and 5th ribs. After determining the fascia between the two muscles, the block needle will be advanced from caudal to cranial and 40 ml of 0.25% bupivacaine (local anesthetic) will be injected on the serratus muscle between the two muscles.