TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05021471

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: biofeedback
Description: Twenty nine (29) patients will be treated stretching of hamstring with pressure biofeedback.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: hamstrings stretching
Description: Twenty nine (29) patients will be treated stretching of hamstring without pressure biofeedback.
Study: NCT06406166

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lifei Xiaoji Wan
Description: The Lifei Xiaoji Wan consists of ginseng, blackhead, rhubarb, aster, forehu, and thin on

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional treatment with Western medicine
Description: Conventional treatment with Western medicine
Study: NCT05753540

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laser therapy
Description: Multiwave locked system laser therapy

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham laser therapy
Description: Sham laser therapy
Study: NCT06234176

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalised psychomotor therapy
Description: The content of the sessions will be personalised and determined solely by a qualified psychomotor therapist in charge of the patient, based on each participant's individual psychomotor profile, as determined from the initial assessment.~The 12 sessions will take place with the same PT in a dedicated room at the centre where the patient is being treated. The sessions will consist of a range of playful static and dynamic body exercises, including exercises for emotional and tonic regulation, tonic-postural adaptation, and perceptual-motor adaptation.~Not all participants in the GP group will have the same progression, nature or frequency of exercises over the 12 sessions.~The study only allows for individual treatment. Other therapeutic approaches such as balneotherapy sessions, animal mediation, adapted physical activity programmes or targeted relaxation programmes are not permitted.~During each session, the participant will be required to complete the Duke health profile.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual treatment
Description: Participants in the GC group will continue to receive their usual depression treatment without any changes to their prescribed therapies. Their participation in the study will involve weekly monitoring of their quality of life using the Duke scale. A nurse or psychomotor therapist will conduct this monitoring during a weekly fifteen-minute telephone interview. The follow-up will begin one week after the inclusion visit and will last for 12 weeks. Telephone appointments will be scheduled jointly with the participant based on their availability.
Study: NCT06121804

Intervention type: DRUG
Intervention: Immunosuppressive Agents
Description: Prescribing immunosuppressive agents

Intervention type: DRUG
Intervention: Immunosuppressive Agents
Description: Prescribing immunosuppressive agents
Study: NCT06154928

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Drinking Warm Water Intervention
Description: Patients in the Warm Water Group (WG) received a warm water drinking intervention post-laparoscopic cholecystectomy. Before intake, the bed head was elevated to 45°C, and gagging and swallowing reflexes were assessed using an Abeslang to touch the oropharynx. Nausea indicated a positive reflex. Two patients with negative reflexes were excluded from WG. To maintain water temperature, individual insulated cups with thermal features were used, preventing infection transmission. Water was boiled in a clinic kettle, cooled to 37-38°C, and given to patients to drink within 15 minutes. Swallowing ability was monitored after the first sip; successful swallowing allowed the patient to continue. Patients were observed for 15 minutes with an aspirator on standby for aspiration risks. No complications occurred during the water drinking process in WG.
Study: NCT06497803

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nurse-Led Body Protection Education
Description: Based on BST and Safe Touches education programs and in line with the studies conducted in the literature on children who are not visually impaired, NLBPE was created by the researchers (Akgul et al., 2021; Citak-Tunc et al., 2018; Pulido, 2019; Wurtele, 2007). The program aims to teach visually impaired children how to protect the private parts of their bodies, to distinguish between good and bad touch, to distinguish between good and bad secrets, to say no, scream, and ask for help when necessary. As education tools, dolls and distress whistles were used. In order for children to learn the private parts of their bodies, a doll was used. The practice of Say No, Scream, Run, and Blow Your Whistle While Running in order for the students to protect their body from bad touch was applied by the students one by one firstly, and in groups later.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reminder Education Brochure
Description: The brochure was prepared in line with the NLBPE and included what is a good touch and a bad touch, how to distinguish a good touch from a bad touch, examples of good touch and bad touch, and what to do when encountered with a bad touch (Say No, Scream, Run, and Blow Your Whistle While Running). The brochure, the content of which was prepared by the researcher, was translated into Braille Alphabet by a visually impaired teacher working at the school where the research was conducted, before it was distributed to the intervention group members.
Study: NCT06327776

Intervention type: OTHER
Intervention: Serum and saliva biomarkers
Description: 2x5mL blood samples and saliva samples will be used to determine the performance of different blood based and saliva biomarkers for determining diagnostic management and prognosis in mTBI patients.
Study: NCT06342336

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-IT101 Injection
Description: Adoptive transfer of 5x10\^9-6x10\^10 autologous TIL to patients i.v. in 30-60 minutes.
Study: NCT05275582

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CARE
Description: Behavioral intervention including~-30 minute meeting alone with behavioral health educator (in person or virtual using VA's VVC system) 4 weeks of optional self monitoring using an app of substance use behavior, mood, other behavioral processes 2 optional 15-minute phone calls with behavioral health educator

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CARE
Description: Behavioral intervention including~-30 minute meeting alone with behavioral health educator (in person or virtual using VA's VVC system) 4 weeks of optional self monitoring using an app of substance use behavior, mood, other behavioral processes 2 optional 15-minute phone calls with behavioral health educator
Study: NCT05880667

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Adaptive Stereotactic Body Radiation
Description: Radiation therapy is given following generation of planning imaging at the time of simulation. A recent development has been diagnostic quality onboard imaging incorporated within radiation treatment machines. The incorporation of onboard imaging into standard practice has allowed the use Stereotactic Body Radiation (SBRT), which is a precise radiation technique that allows safe delivery of ablative radiation doses.~More recently, the development of improved technologies and software have allowed radiation plans to be generated and delivered that are specific to the anatomy of the very moment the patient is being treated. This novel ability to adjust the radiation treatment plan based upon real time imaging is termed adaptive radiation therapy. This study will utilize the novel adaptive radiation therapy technology in a patient population with technically challenging disease to deliver ablative radiation with an appropriately low toxicity rate.
Study: NCT05615142

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Low Dose Radiotherapy
Description: LDRT at dose escalation levels: 2 Gy/1f, 4 Gy/2f, 6 Gy/3f with conventional external beam radiation.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: stereotactic body radiation therapy
Description: Partial SBRT at dose escalation levels: 10 Gy/1f, 20 Gy/2f, 30 Gy/3f.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 Inhibitors
Description: Patients will receive treatment with PD-1 inhibitor (dose as recommended in the instruction manual) every 3 weeks for a maximum of 48 months.
Study: NCT04757805

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound
Description: Ultrasound to locate the appropriate lumbar interspace to perform spinal anesthesia.
Study: NCT06004323

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital health literacy intervention
Description: Participants from the intervention group will be invited to join virtual or face-to-face training, watch short videos on social media, participate in virtual bi-weekly group discussion, and fill in questionnaires for five times during the course of the study
Study: NCT04660786

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: triamcinolone acetonide
Description: local immunosuprresent

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: vitamin D
Description: local immunomodulator
Study: NCT05536375

Intervention type: OTHER
Group type: OTHER
Intervention: Exhaled breath condensate collection and blood draw
Description: Venepuncture- 10mls of blood to be collected~and~Exhaled breath condensate (EBC) collection method- this involved breathing in and out through a disposable device (akin to breathing onto cold glass to produce condensate) with an external cooler device. The R Tube starter kit is a complete disposable EBC collection kit and It has been used in many research clinical investigations.
Study: NCT06091059

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound MRI fusion
Description: Fused MRI images with direct ultrasound guidance
Study: NCT06454045

Intervention type: DRUG
Intervention: Clopidogrel
Description: Clopidogrel 75 mg once a day for 14 days.

Intervention type: DRUG
Intervention: Clopidogrel
Description: Clopidogrel 75 mg once a day for 14 days.
Study: NCT04641169

Intervention type: PROCEDURE
Group type: OTHER
Intervention: echocardiography
Description: Four measurements in echocardiography performed in addition to standard care
Study: NCT04210999

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Homebased resistance training
Description: Resistance training at home instructed via a smart phone training app

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Supervised heavy slow resistance training
Description: Heavy slow resistance training in the gym instructed by a physiotherapist
Study: NCT05707247

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: software
Description: The experimental medical device is a prototype software. It is a patient interface.~The device comes in the form of a smartphone with a touch screen
Study: NCT05575297

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate Sodium
Description: Methotrexate oral administration alone

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate Sodium
Description: Methotrexate oral administration alone

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate Sodium
Description: Methotrexate oral administration alone

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate Sodium
Description: Methotrexate oral administration alone

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifampicin Sodium
Description: Co-administration of methotrexate and rifampicin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifampicin Sodium
Description: Co-administration of methotrexate and rifampicin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Febuxostat Tablets
Description: Co-administration of methotrexate and febuxostat

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Febuxostat Tablets
Description: Co-administration of methotrexate and febuxostat
Study: NCT04936685

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Meningococcal Polysaccharide (Serogroups A, C, W, and Y) Tetanus Toxoid Conjugate Vaccine
Description: Liquid solution for injection Intramuscular

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Meningococcal Polysaccharide (Serogroups A, C, W, and Y) Tetanus Toxoid Conjugate Vaccine
Description: Liquid solution for injection Intramuscular
Study: NCT06013514

Intervention type: DEVICE
Intervention: PERLE Sterile Smooth Opaque gel filled mammary implants
Description: Sterile smooth opaque gel filled mammary implants will be implanted in adult women having breast surgery for either augmentation, reconstruction or revision surgery. Different ranges of implants will be used to suit patient needs
Study: NCT05392647

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hetrombopag
Description: All eligible patients were given hetrombopag orally at an initial dose of 5 mg once daily after overnight fasting (\>8 hours of fasting) and at least 2 hours before a meal . The dose of hetrombopag could be modified on the basis of the platelet count of patients after 2 weeks of administration.
Study: NCT05761613

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CeraShield Endotracheal Tube
Description: An endotracheal tube coated with with an antimicrobial hydrophilic coating containing ceragenins (CSAs)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Endotracheal tube with subglottic secretion drainage
Description: An endotracheal tube with subglottic secretion drainage
Study: NCT05051969

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remote Mindfulness-Based Stress Reduction Program
Description: Enrolled participants will participate in a remote-delivered (online with audio and video) Mindfulness-Based Stress Reduction (MBSR) program. MBSR is a well established behavioral health intervention consisting of 10-sessions lasting 2.5 hours, with one session lasting 7.5 hours in an all-day retreat format over a 2-month period.
Study: NCT04331093

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1210+Apatinib
Description: Drug: SHR-1210 SHR-1210 will be administered as a 30-minute IV infusion Q2W at a dose of 200mg~Drug: Apatinib Apatinib tablet will be administered orally,once daily until progression
Study: NCT06323213

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 610
Description: 610 subcutaneously injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo subcutaneously injection.
Study: NCT04969588

Intervention type: DIAGNOSTIC_TEST
Intervention: Microsoft Azure Kinect Developer Kit
Description: 3D images and 3D joint coordinates are obtained.

Intervention type: DIAGNOSTIC_TEST
Intervention: Bioelectrical impedance analyzer
Description: Fat mass, fat-free mass and percentage body fat in total body and body segments are estimated.

Intervention type: DIAGNOSTIC_TEST
Intervention: Dual Energy X-ray Absorptiometry
Description: Skeletal length and body composition are estimated.
Study: NCT04739592

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: alendronate sodium vitamin D3 tablets
Description: once per week for one year

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: once per week for one year
Study: NCT05274529

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological health and flexibility
Description: A remote coaching programme concentrating on psychological health and flexibility

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Work ability
Description: A remote coaching programme concentrating on work ability

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep and recovery
Description: A remote coaching programme concentrating on sleep and recovery

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy lifestyle
Description: A remote coaching programme concentrating on healthy lifestyle

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No coaching
Description: Participants also have the option to choose no coaching for the coming 3 month period.
Study: NCT04591171

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: n-of-1 trial guided clinical decision making
Description: The n-of-1 trial will, on the level of the individual patient, test which treatment strategy produces superior blood pressure reduction without unacceptable side effects. After discussion with the patient/caregiver dyad to identify whether they have specific concerns about particular medications, the nephrologist (clinician) will decide which two drugs and dosages will be tested in the n-of-1 trial (the protocol does not determine drug or dose). The two drugs chosen by the clinician will be assessed at clinician-selected dosing in a randomized treatment order (e.g., ABAB) for two weeks per treatment period and two treatment periods per drug.
Study: NCT05492851

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zilretta
Description: Intra-articular injection to treat knee osteoarthritis

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Synvisc-One 48 MG in 6 ML Prefilled Syringe
Description: Intra-articular injection to treat knee osteoarthritis

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Monovisc 88 MG Per 4 ML Prefilled Syringe
Description: Intra-articular injection to treat knee osteoarthritis
Study: NCT04716751

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Neoadjuvant treatment stage: Toripalimab 240mg, Carboplatin AUC5+ paclitaxel 200 mg/m ², iv, 3 weeks per cycle, 2-4 cycles in total; Surgical treatment stage: Patients with tracheal malignant tumor received radical surgery after neoadjuvant therapy, and patients who could not or refused surgical treatment due to various reasons were treated with multidisciplinary discussion.~Adjuvant treatment stage: Toripalimab 240mg, Carboplatin AUC5+ paclitaxel 200 mg/m ²,iv, up to 4 cycles (including neoadjuvant stage).
Study: NCT05809505

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 360-degree Turn Test
Description: The 360-degree turn test is a measure of dynamic balance. The person tested turns in a complete circle (360 degrees) while the time to complete and/or the number of steps to complete the turn is recorded.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Expanded Disability Status Scale
Description: The Expanded Disability Status Scale (EDSS) is a method of quantifying disability in multiple sclerosis and monitoring changes in the level of disability over time. It is widely used in clinical trials and in the assessment of people with multiple sclerosis. The EDSS scale ranges from 0 to 10 in 0.5 unit increments that represent higher levels of disability.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Perceived Exertion
Description: The Borg Rating of Perceived Exertion (RPE) is a way of measuring physical activity intensity level. Perceived exertion is how hard you feel like your body is working. It is based on the physical sensations a person experiences during physical activity, including increased heart rate, increased respiration or breathing rate, increased sweating, and muscle fatigue. Although this is a subjective measure, your exertion rating based on a 6 to 20 rating scale, may provide a fairly good estimate of your actual heart rate during physical activity.
Study: NCT05733182

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 3000K Reading lamp
Description: Reading lamp with custom-made circuitry to emit light of 3000K colour temperature

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 4500K Reading lamp
Description: Reading lamp with custom-made circuitry to emit light of 4500K colour temperature
Study: NCT04711343

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT2306
Description: 150mg/1 ml; single dose；prefilled syringe; subcutaneous injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cosentyx (US-licensed)
Description: 150mg/1 ml; single dose；prefilled syringe; subcutaneous injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cosentyx (EU-licensed)
Description: 150mg/1 ml; single dose；prefilled syringe; subcutaneous injection
Study: NCT04745871

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PSMA PET/CT
Description: The PSMA PET/CT will be performed on an outpatient in the nuclear medicine department of the Brest University Hospital (CHRU). For this exam, the administration of 2-4 MBq/kg of 68Ga-HBED-CC-PSMA will be performed to patient by a single intravenous injection.
Study: NCT05162430

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: 0.1mg/kg, 0.2mg/kg, 0.3mg/kg, 0.4mg, kg, 0.5mg/kg Propofol was injected to five groups of P1, P2, P3, P4 and P5, respectively, and 5mg dexamethasone sodium phosphate was given to groups P1, P2, P3, P4, P5 and D1 after 30s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: 0.1mg/kg, 0.2mg/kg, 0.3mg/kg, 0.4mg, kg, 0.5mg/kg Propofol was injected to five groups of P1, P2, P3, P4 and P5, respectively, and 5mg dexamethasone sodium phosphate was given to groups P1, P2, P3, P4, P5 and D1 after 30s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: 0.1mg/kg, 0.2mg/kg, 0.3mg/kg, 0.4mg, kg, 0.5mg/kg Propofol was injected to five groups of P1, P2, P3, P4 and P5, respectively, and 5mg dexamethasone sodium phosphate was given to groups P1, P2, P3, P4, P5 and D1 after 30s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: 0.1mg/kg, 0.2mg/kg, 0.3mg/kg, 0.4mg, kg, 0.5mg/kg Propofol was injected to five groups of P1, P2, P3, P4 and P5, respectively, and 5mg dexamethasone sodium phosphate was given to groups P1, P2, P3, P4, P5 and D1 after 30s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: 0.1mg/kg, 0.2mg/kg, 0.3mg/kg, 0.4mg, kg, 0.5mg/kg Propofol was injected to five groups of P1, P2, P3, P4 and P5, respectively, and 5mg dexamethasone sodium phosphate was given to groups P1, P2, P3, P4, P5 and D1 after 30s
Study: NCT05403840

Intervention type: PROCEDURE
Intervention: Mitral valve surgery
Description: Surgical mitral valve repair or replacement

Intervention type: PROCEDURE
Intervention: Transcatheter mitral valve intervention
Description: Transcatheter mitral valve repair or replacement
Study: NCT05481827

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: GT005
Description: GT005 is a gene therapy for GA and is a recombinant adeno-associated viral serotype 2 (AAV2) vector encoding for human complement factor I. GT005 was administered to all participants in an antecedent study prior to enrollment in ORACLE and GT005 is not administered in the ORACLE study.
Study: NCT06121531

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Soft Contact Lens
Description: Vision Correction

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Soft Contact Lens
Description: Vision Correction