TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05764473

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The impact of MedDiet on cardiometabolic risk factors and menopause symptoms
Description: 12-week randomised parallel cross-over study with 32 participants. Impact of diet on CMR factors and menopause symptoms will be explored with diet quality and adherence to diet determined via diet quality indices for MedDiet and Portfolio diet.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The impact of MedDiet on cardiometabolic risk factors and menopause symptoms
Description: 12-week randomised parallel cross-over study with 32 participants. Impact of diet on CMR factors and menopause symptoms will be explored with diet quality and adherence to diet determined via diet quality indices for MedDiet and Portfolio diet.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The impact of UCLP on cardiometabolic risk factors and menopause symptoms
Description: 12-week randomised parallel cross-over study with 32 participants. Impact of diet on CMR factors and menopause symptoms will be explored with diet quality and adherence to diet determined via diet quality indices for MedDiet and Portfolio diet.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The impact of UCLP on cardiometabolic risk factors and menopause symptoms
Description: 12-week randomised parallel cross-over study with 32 participants. Impact of diet on CMR factors and menopause symptoms will be explored with diet quality and adherence to diet determined via diet quality indices for MedDiet and Portfolio diet.
Study: NCT05502159

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: M-TAPA
Description: Under aseptic conditions, a high-frequency linear probe will be placed on the costochondral angle in the sagittal plane. Then the probe will be slightly angled deeply to visualize the lower view of the perichondrium. We will perform M-TAPA with total of 40 ml (20 ml for each side) of %0,25 bupivacaine.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: EOB
Description: In the supine position, a high-frequency linear US probe (11-12 MHz, Vivid Q) will be covered with a sterile sheath, and an 80 mm block needle (Braun 360°) will be used. The US probe will be placed on the midaxillary line between the spina iliaca anterior superior and the umbilicus. Using the In-Plane technique, 5 ml of saline will be injected under the external oblique muscle of the block needle and the block location will be confirmed. After the block location is confirmed, 20 ml of 0.25% bupivacaine will be administered. The same procedure will be applied to the other side (40 ml of 0.25% bupivacaine in total).
Study: NCT05533203

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Prodencel; an autologous dendritic cell therapeutic tumor vaccine
Description: Subcutaneous injection, each injection point should not exceed 1ml.
Study: NCT05652231

Intervention type: DIAGNOSTIC_TEST
Intervention: caries assessment
Description: the child will examined for dental caries, caries prevalence, caries indices (def and DMF, or DMF)

Intervention type: DIAGNOSTIC_TEST
Intervention: caries assessment
Description: the child will examined for dental caries, caries prevalence, caries indices (def and DMF, or DMF)

Intervention type: DIAGNOSTIC_TEST
Intervention: caries assessment
Description: the child will examined for dental caries, caries prevalence, caries indices (def and DMF, or DMF)
Study: NCT05517369

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hybrid ESD+
Description: Injection of the Lift Up solution, followed by circumcision of the lesion using a snare tip or ESD knife. Using an additional working channel (AWC), the lesion is resected using a grasper and snare.
Study: NCT01269359

Intervention type: PROCEDURE
Intervention: robotic assisted surgery
Description: Robotic guidance: SpineAssist™ (Mazor Surgical Technologies, Caesarea, Israel), is a bone-mounted miniature robot. It is a semi-active system offering surgical tool guidance while leaving performance of the actual surgical operation, such as the drilling, in the surgeon's hands.
Study: NCT06299982

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 608 Q2W
Description: 608 160 mg at week 0 + 80 mg Q2W (5 cycles)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 608 Q4W
Description: 608 160 mg Q4W (3 cycles)
Study: NCT04905446

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Skin tissue biopsy
Description: This procedure is used to sample skin tissue from the upper thigh via a punch biopsy.
Study: NCT05898815

Intervention type: DIAGNOSTIC_TEST
Intervention: Medical record collection
Description: Medical record collection
Study: NCT05110469

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium sulfate
Description: IV Magnesium sulphate 30 mg/kg, labeled as research drug for blinding, were given in 10 minutes while patients were monitored for side effects such as hypotension, bradycardia, nausea, vomiting, itch, allergy, drowsiness, and respiratory depression.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meperidine
Description: IV Meperidine 0.5 mg/kg, labeled as research drug for blinding, were given in 10 minutes while patients were monitored for side effects such as hypotension, bradycardia, nausea, vomiting, itch, allergy, drowsiness, and respiratory depression.
Study: NCT06482320

Intervention type: DIAGNOSTIC_TEST
Intervention: Recording EKG traces on the smartwatch
Description: Upon enrollment, patients are associated with a progressive identification number (ID). They will then be instructed to record a baseline single-lead EKG (EKG 0) to be sent to a dedicated email address. The sender's email address will be recorded and associated with the ID. The main clinical and demographic data will also be collected. Within 30 days of the enlistment date, a 24-hour EKG Holter will be performed. From the date of enlistment and for the following three months, before, after and during the execution of the 24-hour EKG Holter, enrolled patients can send single-lead EKGs (recorder throug the smartwatch) in case of palpitation. The report of the single-lead EKGs will be communicated electively via e-mail (in response to the email sent by the patient and containing the trace in question) in the following days. In case of diagnostic and/or therapeutic measures to be implemented following the reporting of the trace, doctors will take care of it.
Study: NCT05023473

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pericapsular nerve group block
Description: patients will receive pericapsular nerve group block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine Sulfate
Description: morphine will be given to both groups as patient-controlled analgesia PCA

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine Sulfate
Description: morphine will be given to both groups as patient-controlled analgesia PCA
Study: NCT06300723

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BRL-101
Description: CD34 + autologous hematopoietic stem and progenitor cells edited at the BCL11A gene.
Study: NCT04994782

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GAME-EOL
Description: The GAME-EOL involves Hello game booklets as well as meetings with an interventionist. Players (ICD recipient and their family member or friend dyad) take turns asking the questions in their booklet and providing their answers to the question. The gameplay continues until all questions are answered or the dyad wishes to stop. Following the completion of the game play, participants will be offered the opportunity to complete advance directives using the conversation guide and advance directive form included in the conversation guide that accompanies the questionnaire booklet.
Study: NCT06105216

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Crossword and word search puzzles
Description: Students in the intervention group received hard copies of the puzzles at the end of the laboratory practice.
Study: NCT06349187

Intervention type: DIAGNOSTIC_TEST
Intervention: Interview
Description: Interviewing with using the Hall Emotional Intelligence test, the Maslach emotional burnout test, and the test for determining general and specialized digital competencies
Study: NCT05929378

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Lightweight mesh fixation
Description: Lightweight mesh fixation in 3 points

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lightweight mesh fixation
Description: Lightweight mesh fixation in 3 points
Study: NCT05180318

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato]
Description: Esketamine (0.25 mg/kg) will be given intravenously 24-36 hours before surgery (infusion time: 40 min) and immediately after surgery (infusion time: 40 min).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% saline
Description: 0.9% saline
Study: NCT05284851

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Live Attenuated Influenza Vaccine(non freeze-dried)
Description: Live Attenuated Influenza Vaccine Live Attenuated Influenza Vaccine placebo, containing H1, H3 and B type influenza Live Attenuated virus.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Live Attenuated Influenza Vaccine(freeze-dried)
Description: Live Attenuated Influenza Vaccine Live Attenuated Influenza Vaccine placebo, containing H1, H3 and B type influenza Live Attenuated virus.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Live Attenuated Influenza Vaccine placebo
Description: Live Attenuated Influenza Vaccine placebo, not containing H1, H3 and B type influenza Live Attenuated virus.
Study: NCT04945902

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Synchronous Intervention
Description: Weekly one-hour support groups. These support groups will meet virtually using a restricted WebEx channel and will be recorded. In this support group, students will discuss the weekly activities and build connection and support with each other. This group will be led by advanced doctoral students in counseling psychology and overseen by a counseling psychology faculty member, who is also a licensed psychologist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Asynchronous Intervention
Description: The asynchronous intervention will provide access to information and resources for mental health support via Brightspace. The intervention will be six weeks long and each week will have a topic. The weekly topics include: (1) identifying feelings; (2) biology of emotions; (3) mindfulness; (4) recognizing and responding to stress; (5) mental health stigma; and (6) self-care/self-advocacy. Each week, you will be required to complete four types of activities: education, reflective exercises, an activity, and a short assessment. All of these resources will be provided on Brightspace to be completed on your own time but the activities must be completed during the week they are assigned. You will not have to interact with other international students if you are in the asynchronous intervention group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asynchronous Intervention
Description: The asynchronous intervention will provide access to information and resources for mental health support via Brightspace. The intervention will be six weeks long and each week will have a topic. The weekly topics include: (1) identifying feelings; (2) biology of emotions; (3) mindfulness; (4) recognizing and responding to stress; (5) mental health stigma; and (6) self-care/self-advocacy. Each week, you will be required to complete four types of activities: education, reflective exercises, an activity, and a short assessment. All of these resources will be provided on Brightspace to be completed on your own time but the activities must be completed during the week they are assigned. You will not have to interact with other international students if you are in the asynchronous intervention group.
Study: NCT05022784

Intervention type: DRUG
Intervention: Nintedanib
Description: Nintedanib
Study: NCT05791266

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sticker pads containing lavender and ylang ylang oil
Description: Sticker pads , size 160 mm2, were produced by a certified ISO 9001 manufacturer and contained 0.3% lavender oil and 0.7% ylang ylang oil. The sticker pad was attached to the shirts of healthy volunteers for 2 hours. The outcomes were evaluated before, during and 30 minutes after removal of the pad.
Study: NCT05358171

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HIgh UPF controlled diet
Description: Following a two- week eucaloric lead-in diet, participants will be provided and consume a diet emphasizing UPF (81% energy). Diets will be eucaloric (50% carbohydrate, 35% fat,15% protein) matched for dietary soluble and insoluble fiber, added sugar, mono- and polyunsaturated fat, saturated fat, antioxidant nutrients, sodium, pre- and probiotics, and overall diet quality, for 6 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No UPF controlled diet
Description: Following a two- week eucaloric lead-in diet, participants will be provided and consume a diet without UPF (0% energy). Diets will be eucaloric (50% carbohydrate, 35% fat,15% protein) matched for dietary soluble and insoluble fiber, added sugar, mono- and polyunsaturated fat, saturated fat, antioxidant nutrients, sodium, pre- and probiotics, and overall diet quality, for 6 weeks.
Study: NCT04644887

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention: Healthy diet
Description: Dietary guidance in the intervention group is based on the Nordic and Finnish nutrition recommendations with an emphasis on the quality of dietary fat. The aims for the intake of fatty acids will be SFA \< 10 % of energy intake (E%) and mono- and polyunsaturated fatty acids (UFA) \>2/3 of the total fat intake. The key food products such as vegetable oil-based spread, liquid margarine and canola oil are provided to the participants. The participants are recommended to use fat free (e.g. milk, sourdough milk and yogurt) and low fat (e.g. cheese ≤ 17%) dairy products and low-fat meat, poultry, and fish as well as natural nuts and seeds.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention: Healthy diet
Description: Dietary guidance in the intervention group is based on the Nordic and Finnish nutrition recommendations with an emphasis on the quality of dietary fat. The aims for the intake of fatty acids will be SFA \< 10 % of energy intake (E%) and mono- and polyunsaturated fatty acids (UFA) \>2/3 of the total fat intake. The key food products such as vegetable oil-based spread, liquid margarine and canola oil are provided to the participants. The participants are recommended to use fat free (e.g. milk, sourdough milk and yogurt) and low fat (e.g. cheese ≤ 17%) dairy products and low-fat meat, poultry, and fish as well as natural nuts and seeds.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietary intervention: Control diet
Description: The control diet corresponds to the average nutrient intake in the Nordic countries, i.e. the intake of SFA about 15 E% and the proportion of UFA about 50 % of total fat intake. The participants of the control group will get butter-based spread for bread and cooking. They are recommended to use semi-skimmed milk (1,5 %), normal fat yogurt (\~2%), normal fat cheese (\~24-35 %) and avoid consumption of vegetable oils. They are allowed to eat a portion of fish and nuts once a week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietary intervention: Control diet
Description: The control diet corresponds to the average nutrient intake in the Nordic countries, i.e. the intake of SFA about 15 E% and the proportion of UFA about 50 % of total fat intake. The participants of the control group will get butter-based spread for bread and cooking. They are recommended to use semi-skimmed milk (1,5 %), normal fat yogurt (\~2%), normal fat cheese (\~24-35 %) and avoid consumption of vegetable oils. They are allowed to eat a portion of fish and nuts once a week.
Study: NCT04601779

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: VIPP-PUF
Description: The VIPP-PUF Intervention is developed as an add-on to the existing PUF-program to address infants with major cognitive and regulatory vulnerabilities identified at age 9-10 months and adapted to the settings of community health nurses. The intervention (VIPP-PUF) will be created from an evidence-based method, the Video-based Intervention to Promote Positive Parenting (VIPP), to comprise six therapeutic sessions delivered by the community health nurse during home visits over a three months period. The VIPP -PUF builds on teaching the health nurses to promote parents' sensitivity to meet infants' cognitive and regulatory vulnerabilities, while taking in account the particular needs of families of psycho-social disadvantage.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: VIPP-PUF
Description: The VIPP-PUF Intervention is developed as an add-on to the existing PUF-program to address infants with major cognitive and regulatory vulnerabilities identified at age 9-10 months and adapted to the settings of community health nurses. The intervention (VIPP-PUF) will be created from an evidence-based method, the Video-based Intervention to Promote Positive Parenting (VIPP), to comprise six therapeutic sessions delivered by the community health nurse during home visits over a three months period. The VIPP -PUF builds on teaching the health nurses to promote parents' sensitivity to meet infants' cognitive and regulatory vulnerabilities, while taking in account the particular needs of families of psycho-social disadvantage.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: VIPP-PUF
Description: The VIPP-PUF Intervention is developed as an add-on to the existing PUF-program to address infants with major cognitive and regulatory vulnerabilities identified at age 9-10 months and adapted to the settings of community health nurses. The intervention (VIPP-PUF) will be created from an evidence-based method, the Video-based Intervention to Promote Positive Parenting (VIPP), to comprise six therapeutic sessions delivered by the community health nurse during home visits over a three months period. The VIPP -PUF builds on teaching the health nurses to promote parents' sensitivity to meet infants' cognitive and regulatory vulnerabilities, while taking in account the particular needs of families of psycho-social disadvantage.
Study: NCT05222100

Intervention type: DIAGNOSTIC_TEST
Intervention: Mammography screening
Description: Breast screening mammograms use X-rays to look for cancers that are too small to see or feel.

Intervention type: DIAGNOSTIC_TEST
Intervention: Mammography screening
Description: Breast screening mammograms use X-rays to look for cancers that are too small to see or feel.
Study: NCT04759794

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cytology staining
Description: Two stainings will be performed in cytology specimens obtained from the same patient. The cytology specimen will be obtained through brushing cytology using endoscopic retrograde cholangiopancreatography~1. conventional cytology staining method~2. new cytology staining method using the antibody of aminoacyl-tRNA synthetases
Study: NCT05039242

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy)
Description: Participants will receive a Hand exercise program including 8 different movements according to Flat 20 (flexion, extension, radial deviation of the fingers, dorsal flexion, palmar flexion, ulnar deviation of the fingers, and opposition and abduction of thumbs.~Repetitions include 5 times during each session, as given in the study. Balanced resistive hand exercise with use of physio hand ball squeezes including finger abduction and adduction exercises with MCP extended and gross grip.~Each contraction to be held for 3-5 seconds with a 20-second rest between contractions. Five repetitions of each resistive exercise will be done.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotaping with I shaped application
Description: Participants will receive Kinesiotape, by using I application technique from proximal to distal on dorsum of hand and forearm with less than 50% stretch of the subjects on both hands, once a week for a total time period of 4 weeks with 4 KT applications in total (19). Kinesiotape will be worn by the subjects for 3 days. basic hand exercises will accompny it. Weekly assessments will be completed for pain, ROM, joint stiffness, grip strength and ADLs.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotaping with Fan-shaped Application
Description: Participants will receive exercise interventions as group A along with that the Kinesiotape will be applied, by using fan cut application technique on MCP joints involving extensor tendons of fingers on dorsal surface of both hands of subjects, once a week for a total time period of 4 weeks with 4 KT applications in total.~Kinesiotape will be worn by the subjects for 3 days. Less than 50% stretch with space correction technique. basic hand exercises will accompny it. Weekly assessments will be completed for pain, ROM, joint stiffness, grip strength and ADLs.
Study: NCT05590065

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ABLE Exoskeleton
Description: The ABLE Exoskeleton is a lower-limb overground robotic exoskeleton intended for SCI patients for rehabilitation in a clinical setting.
Study: NCT04634747

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PVX-410
Description: PVX-410 in combination with pembrolizumab and chemotherapy
Study: NCT05584176

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iCura COVID-19 Antigen Rapid Home Test
Description: Candidate Ag self-test kit anterior nasal specimen collection and testing will be done under the supervision of qualified site personnel in person. Comparator NP samples shall be collected at least 15 minutes prior to Ag samples with at least 15 minutes between nasal collections including collections that may occur prior to study enrollment. Comparator samples will be collected first by qualified personnel at a study site or physician's office using an FDA authorized nasopharyngeal swab collection kit and SARS-CoV-2 molecular assay.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iCura COVID-19 Antigen Rapid Home Test
Description: Candidate Ag self-test kit anterior nasal specimen collection and testing will be done under the supervision of qualified site personnel in person. Comparator NP samples shall be collected at least 15 minutes prior to Ag samples with at least 15 minutes between nasal collections including collections that may occur prior to study enrollment. Comparator samples will be collected first by qualified personnel at a study site or physician's office using an FDA authorized nasopharyngeal swab collection kit and SARS-CoV-2 molecular assay.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RT-PCR Test
Description: High sensitivity RT-PCR COVID-19 Test

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RT-PCR Test
Description: High sensitivity RT-PCR COVID-19 Test
Study: NCT05916391

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-003
Description: Administration via intraocular injection

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-003
Description: Administration via intraocular injection

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-003
Description: Administration via intraocular injection