TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04885829

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tocilizumab Prefilled Syringe
Description: 0.9ml Subcutaneous pre-filled syringes containing 162mg of Tocilizumab.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tocilizumab Prefilled Syringe
Description: 0.9ml Subcutaneous pre-filled syringes containing 162mg of Tocilizumab.
Study: NCT05839093

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Inferior Alveolar Nerve Block Group
Description: A standard IANB injection with a conventional dental injector and a 27-G needle. After determining the injection site and performing aspiration, 1.8 mL of solution was injected at a rate of 1 mL/min to block the inferior alveolar nerve. After achieving lip anesthesia, infiltration was performed at the buccal side of the affected tooth with 0.5 mL using a normal syringe and a 27-G needle. The needle insertion point was the middle of the mesiodistal distance of the crown. Five minutes later, the teeth were isolated and the endodontic procedure was started.
Study: NCT04945395

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FES and Conventional training
Description: The experimental group will be fitted with the Functional electrical stimulation system L300 Go to be used during 4 weeks of inpatient rehabilitation in the subacute phase after hemiplegic stroke. Settings will be adjusted continuously to enhance dorsiflexion of the affected foot during walking and mobility training.
Study: NCT06019468

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Envolizumab combined with radiotherapy
Description: Application of Envolizumab combined with radiotherapy for neoadjuvant treatment of locally advanced thymic cancer. Firstly, 20-40Gy radiation therapy was administered 10-20 times. Within one week after the start of radiation therapy, Envolizumab (300 mg, D1, Q3W, subcutaneous injection) was administered. Immunotherapy was maintained for 2-4 cycles, and surgery was performed after evaluation by the attending physician.
Study: NCT05343702

Intervention type: DRUG
Intervention: priming with rocuronium
Description: Following induction (paralysis after onset of the induction effect) in routine rapid sequence intubation protocols While paralysis is applied, it is aimed to shorten the half-life of rocuronium by administering a subparalytic dose of rocuronium approximately 3-5 minutes before induction in the priming technique
Study: NCT05156138

Intervention type: OTHER
Intervention: no interventions as it is a case control observational study
Description: no interventions as it is a case control observational study

Intervention type: OTHER
Intervention: no interventions as it is a case control observational study
Description: no interventions as it is a case control observational study
Study: NCT05839093

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraligamentary Injection Group
Description: An infiltration was performed at the buccal side of the affected tooth with 0.5 mL using a normal syringe and a 27-G needle. Then, an intraligamentary injection was performed with a special pressure injection syringe (Sopira Citoject, Kulzer, Hanau, Germany) and a 30-G needle. The needle was placed alongside the tooth and inserted at a 30 angle relative to the longitudinal axis of the crown with the needle between the teeth and the bone. Then, in the mesiobuccal, distobuccal, mesiolingual and distolingual portions of teeth, 0.18 mL of the solution was injected. Five minutes later, the teeth were isolated and the endodontic procedure was started.
Study: NCT05106257

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-management education (long)
Description: The self-management education condition is based on the Living Well with COPD program. The program consists of a mailed booklet and structured phone counseling delivered by certified COPD educators. Topics include disease information, breathing retraining, action planning, medication use, energy conservation, and following good health habits. The long condition consists of five, weekly calls (30-45 minutes each) following a structured curriculum of patient education topics.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-management education (long)
Description: The self-management education condition is based on the Living Well with COPD program. The program consists of a mailed booklet and structured phone counseling delivered by certified COPD educators. Topics include disease information, breathing retraining, action planning, medication use, energy conservation, and following good health habits. The long condition consists of five, weekly calls (30-45 minutes each) following a structured curriculum of patient education topics.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-management education (long)
Description: The self-management education condition is based on the Living Well with COPD program. The program consists of a mailed booklet and structured phone counseling delivered by certified COPD educators. Topics include disease information, breathing retraining, action planning, medication use, energy conservation, and following good health habits. The long condition consists of five, weekly calls (30-45 minutes each) following a structured curriculum of patient education topics.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-management education (long)
Description: The self-management education condition is based on the Living Well with COPD program. The program consists of a mailed booklet and structured phone counseling delivered by certified COPD educators. Topics include disease information, breathing retraining, action planning, medication use, energy conservation, and following good health habits. The long condition consists of five, weekly calls (30-45 minutes each) following a structured curriculum of patient education topics.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-management education (long)
Description: The self-management education condition is based on the Living Well with COPD program. The program consists of a mailed booklet and structured phone counseling delivered by certified COPD educators. Topics include disease information, breathing retraining, action planning, medication use, energy conservation, and following good health habits. The long condition consists of five, weekly calls (30-45 minutes each) following a structured curriculum of patient education topics.
Study: NCT05191576

Intervention type: OTHER
Intervention: Children's sleep habits questionnaire (CSHQ)
Description: 1. Children's Sleep Habits Questionnaire is a validated tool to screen sleep behavior in young children's assessment of pediatric sleep problems.~2. DSM-V Level II Sleep Disturbance- Child Report. is retrospective, 8-item self-report used to assess the pure domain of sleep disturbances in children and adolescents age of 11-17 years in the past seven days.Higher scores indicate more severe sleep disorders. High scores on a particular domain might indicate significant and problematic areas for the child that may warrant further assessment.~3. DSM -V Sleep Disturbance -Adult Report. is used to assess the pure domain of sleep disturbances in adults for the past seven days.~   SDQ).is used to screen emotional and behavioral problems in children.~4. SDQ is used to screen emotional and behavioral problems in children.

Intervention type: OTHER
Intervention: Children's sleep habits questionnaire (CSHQ)
Description: 1. Children's Sleep Habits Questionnaire is a validated tool to screen sleep behavior in young children's assessment of pediatric sleep problems.~2. DSM-V Level II Sleep Disturbance- Child Report. is retrospective, 8-item self-report used to assess the pure domain of sleep disturbances in children and adolescents age of 11-17 years in the past seven days.Higher scores indicate more severe sleep disorders. High scores on a particular domain might indicate significant and problematic areas for the child that may warrant further assessment.~3. DSM -V Sleep Disturbance -Adult Report. is used to assess the pure domain of sleep disturbances in adults for the past seven days.~   SDQ).is used to screen emotional and behavioral problems in children.~4. SDQ is used to screen emotional and behavioral problems in children.
Study: NCT06486259

Intervention type: OTHER
Intervention: Controlled mechanical ventilation
Description: Patients were ventilated under similar tidal volume, respiratory rate, and plateau pressure. PEEP was the adjustment variable to reach a similar plateau pressure

Intervention type: OTHER
Intervention: Controlled mechanical ventilation
Description: Patients were ventilated under similar tidal volume, respiratory rate, and plateau pressure. PEEP was the adjustment variable to reach a similar plateau pressure
Study: NCT04969250

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Moderna mRNA-1273 COVID-19 vaccine
Description: 100 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Moderna mRNA-1273 COVID-19 vaccine
Description: 100 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Moderna mRNA-1273 COVID-19 vaccine
Description: 100 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Moderna mRNA-1273 COVID-19 vaccine
Description: 100 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pfizer BNT162b2 COVID-19 vaccine
Description: 30 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pfizer BNT162b2 COVID-19 vaccine
Description: 30 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pfizer BNT162b2 COVID-19 vaccine
Description: 30 µg intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pfizer BNT162b2 COVID-19 vaccine
Description: 30 µg intramuscular injection
Study: NCT06046573

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support and information
Description: Emotional and technical support. Information about the long-term effects of cancer.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral activation
Description: Behavioral activation with existential themes and emphasis on values and relationships.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral activation
Description: Behavioral activation with existential themes and emphasis on values and relationships.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral activation
Description: Behavioral activation with existential themes and emphasis on values and relationships.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral activation
Description: Behavioral activation with existential themes and emphasis on values and relationships.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Systematic exposure with mindfulness training
Description: Systematic exposure with mindfulness training with a focus on anxiety about health and/or death, body image, and cancer-related trauma.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Systematic exposure with mindfulness training
Description: Systematic exposure with mindfulness training with a focus on anxiety about health and/or death, body image, and cancer-related trauma.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Systematic exposure with mindfulness training
Description: Systematic exposure with mindfulness training with a focus on anxiety about health and/or death, body image, and cancer-related trauma.
Study: NCT06352398

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: erector spina plan block
Description: erector spina plan block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Serratus posterior superior intercostal plan block (SPSIPB)
Description: Serratus posterior superior intercostal plan block (SPSIPB)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.25% bupivacaine
Description: Before the operation, 0.25% bupivacaine 30 ml was administered to both groups.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.25% bupivacaine
Description: Before the operation, 0.25% bupivacaine 30 ml was administered to both groups.
Study: NCT05377333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3457263
Description: Administered SC.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3457263
Description: Administered SC.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Administered SC.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dulaglutide
Description: Administered SC.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dulaglutide
Description: Administered SC.
Study: NCT06046573

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Systematic exposure with mindfulness training
Description: Systematic exposure with mindfulness training with a focus on anxiety about health and/or death, body image, and cancer-related trauma.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promotion of health behaviors
Description: An overview of self-management techniques in terms of physical exercise, dietary advice, and strategies for improved sleep.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promotion of health behaviors
Description: An overview of self-management techniques in terms of physical exercise, dietary advice, and strategies for improved sleep.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promotion of health behaviors
Description: An overview of self-management techniques in terms of physical exercise, dietary advice, and strategies for improved sleep.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promotion of health behaviors
Description: An overview of self-management techniques in terms of physical exercise, dietary advice, and strategies for improved sleep.
Study: NCT05571917

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP)
Description: This intervention is an integrated psychosocial treatment of two established treatments for chronic pain and Opioid Use Disorder (OUD). This intervention focuses on reducing pain interference and preventing relapse to opioid misuse.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhance Usual Care (EUC)
Description: This intervention consists of psychoeducational materials about chronic pain treatment resources, signs and management of opioid overdose and overdose prevention. This intervention also consists of a brief, remote visit with a study therapist, lasting approximately 15 minutes.
Study: NCT04812912

Intervention type: DIAGNOSTIC_TEST
Intervention: Hormone biomarker analysis
Description: For female patients, hormone biomarker analysis will be performed to measure: anti-Mullerian hormone (AMH), estradiol and FSH in the blood. In male patients, hormone biomarkers of testicular function and spermatogenesis will be monitored: testosterone, inhibin B, steroid hormone binding globulin (SHBG) and FSH. Sperm analysis will also be performed in male patients to monitor changes in sperm count.

Intervention type: DIAGNOSTIC_TEST
Intervention: Hormone biomarker analysis
Description: For female patients, hormone biomarker analysis will be performed to measure: anti-Mullerian hormone (AMH), estradiol and FSH in the blood. In male patients, hormone biomarkers of testicular function and spermatogenesis will be monitored: testosterone, inhibin B, steroid hormone binding globulin (SHBG) and FSH. Sperm analysis will also be performed in male patients to monitor changes in sperm count.

Intervention type: BEHAVIORAL
Intervention: QoL Questionnaires
Description: All participants will respond to protocol questionnaires, which will include both validated questionnaires as well as non-validated ones. This design will allow for basic demographic, psychosocial and sexual-health-related data to be obtained.

Intervention type: BEHAVIORAL
Intervention: QoL Questionnaires
Description: All participants will respond to protocol questionnaires, which will include both validated questionnaires as well as non-validated ones. This design will allow for basic demographic, psychosocial and sexual-health-related data to be obtained.
Study: NCT04945395

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AFO and Conventional training
Description: The control group will be fitted with an ankle-foot-orthosis (AFO) according to clinical practice to enhance dorsiflexion of the foot while taking part in conventional rehabilitation interventions during 4 weeks of inpatient rehabilitation including walking and mobility training in the subacute phase after hemiplegic stroke
Study: NCT04896489

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrocortisone 20 MG
Description: Participants receive Hydrocortisone 20 MG

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants receive placebo
Study: NCT05818735

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electroacupuncture (EA) treatment
Description: The regular acupuncture treatment will be applied at the acupoints including Baihui (GV20), Yintang (GV29), Guanyuan (RN4), Qihai (RN6), bilateral ZuSanli (ST36) and bilateral SanYinjiao (SP6). After needle insertion, rotating or lifting-thrusting manipulation will be applied for 'De qi' sensation. Three pairs of electrodes of the electroacupuncture apparatus will be connected to the needles of GV20 and GV29, and bilateral ST36 and SP6 for 25 minutes, delivering a continuous wave with a frequency of 2-8Hz which is based on the tolerance of each patient. The selection of matching acupuncture points will be determined by the acupuncturist according to the patients' different syndrome patterns.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: sham acupuncture (SA) treatment
Description: The sham acpunture treatment will be applied at the same acupoints as the EA treatment with the Streitberger placebo needles. When the blunt needle tip of the placebo needles touches the skin, the patient will get a pricking sensation, but there is no real needle inserted into the skin. The electroacupuncture apparatus will be set on the table beside the patients and two pairs of electrodes will be connected to the needles at bilateral ST36 and SP6. Acupuncturists will turn on the apparatus but all indicators will be set to '0'. Participants will be informed when needles are removed after 25 minutes. Acupuncturists will use dry cotton balls to press the skin around the acupoints when withdrawing the needles so that patients can feel the withdrawal of the 'needles'.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Escitalopram 10mg
Description: Escitalopram will be used as the antidepressants for relieving patients' depressive mood. The dose of the drug will be the minimum clinical starting dose of 10 mg once daily, taken orally in the morning, for a period of 3 months. During the intervention period, patients will be allowed to increase the drug dose (up to 20 mg) according to their mental status. Patients will record the details of the drug dose, duration of dosing,responses and possible side effects on a drug dairy. Pateints will receive 7 tablets of escitalopram from an independent dispencer at a set time each week. They may receive additional dose of escitalopram once again during the week if necessary and it will be recorded by the dispenser.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo drugs are tablets of the same color and size as escitalopram tablets, consisting mainly of starch, and will be tested for safety before being used in the trial. The way the medication is dispensed, the details of how the medication is administered, the dosage, and the record of the drug diary are consistent with the application of the real drugs.
Study: NCT04866264

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: eNutrition Optimizer
Description: The eNutrition optimizer is based on the electronic food frequency questionnaire (FFQ) used in the multicentre randomized controlled trail DO-HEALTH \[56\] developed by the CAM. The FFQ is split up in sections of 33 food groups and contains 216 items. It asks the user on the relative frequency of consumption of the different foods showing a picture of the food in the portion size of interest. Within the eNutrition Optimizer, the FFQ will be extended to create an output of the user's adherence to the Mediterranean diet, the MIND diet and the adherence with the current dietary recommendations for micro- and macronutrients provided by the Swiss Society for Nutrition and the DACH-references, compare it to the DO-HEALTH population and give recommendations on how to improve the score.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: eNutrition Optimizer
Description: The eNutrition optimizer is based on the electronic food frequency questionnaire (FFQ) used in the multicentre randomized controlled trail DO-HEALTH \[56\] developed by the CAM. The FFQ is split up in sections of 33 food groups and contains 216 items. It asks the user on the relative frequency of consumption of the different foods showing a picture of the food in the portion size of interest. Within the eNutrition Optimizer, the FFQ will be extended to create an output of the user's adherence to the Mediterranean diet, the MIND diet and the adherence with the current dietary recommendations for micro- and macronutrients provided by the Swiss Society for Nutrition and the DACH-references, compare it to the DO-HEALTH population and give recommendations on how to improve the score.