TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05867459

Intervention type: DIAGNOSTIC_TEST
Intervention: Serum creatinine
Description: The test wil be measured for all pt in study to detect of their grade of CKD

Intervention type: DIAGNOSTIC_TEST
Intervention: Alb /creat ratio or 24h urine protein
Description: Test will be measured to detect type and sevirity of proteinuria

Intervention type: DIAGNOSTIC_TEST
Intervention: Serum electrolyte
Description: The test will be measured in all pt to detect renal tubular state

Intervention type: DIAGNOSTIC_TEST
Intervention: Urine analysis
Description: It is mirror of kidney

Intervention type: DIAGNOSTIC_TEST
Intervention: Abdominal ultrasound
Description: To detect the anatomy and any structural abnormality in kidneys

Intervention type: DIAGNOSTIC_TEST
Intervention: Renal biobsy
Description: Is done but not for all pt but for pt that can do it and agree for it .the test is used for detection of type of CKD or type of glomerionephritis

Intervention type: OTHER
Intervention: Clinical assesment
Description: Clinical assessment:~age, kidney disease history, history of DM or HTN ,history of pregnancy during study, therapy in early pregnancy , body weight, body height, and . Mean arterial pressure (MAP) . Body mass index (BMI). According to age and Scr level, the estimated glomerular filtration rate (eGFR) was calculated by CKD-EPI Creatinine Equation (2021)~Evaluation of pregnancy outcomes :Adverse pregnancy outcomes included maternal death, severe preeclampsia ,eclampsia ,duration of hospital stay and type of care need, mode of delivery ,need of blood transfusion , gestational age during delivary for detet preterm birth early preterm or late preterm from or extremely preterm \> 28W, birth weigh for low birthweight ,very low birth weight , extremely low birth weight,NICU admission,IUGR, still birth ,abortion, and neonatal death.
Study: NCT05007769

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ramucirumab
Description: Will be supplied by Lilly Oncology, free of charge to the participant

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab will be commercially available.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-803
Description: Will be supplied free of charge to the participants by ImmunityBio
Study: NCT05653323

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-993
Description: Suspension for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-993
Description: Suspension for oral administration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Suspension for oral administration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Suspension for oral administration.
Study: NCT05351853

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Omnivore
Description: This study will evaluate effects of plant based diets (vegan and vegetarian). 60 omnivore individuals will be included. 20 of the participants will continue their omnivore diet as control group. 20 of the participants will change their diet to vegetarian, and 20 of them will change their diet to vegan.

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Vegetarian
Description: 20 of the participants will change their diet to vegetarian diet. In this group participants will not eat any meat or meat product but can eat/drink milk products, egg and other animal products.

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Vegan
Description: 20 of the participants will change their diet to vegan diet. In this group participants will not eat any kind of animal products.
Study: NCT05342220

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Remote ischemic preconditioning
Description: Remote ischemic preconditioning through inflation of a blood pressure cuff to pressure values \> 200mmHg for 5 minutes followed by 5 minutes of reperfusion (3 times each) before electrocardioversion Electrical cardioversion for atrial fibrillation (100, 150, 200 Joule)

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham preconditioning
Description: Inflation of a blood pressure cuff to pressure values \~ 10mmHg for 5 minutes followed by 5 minutes of reperfusion (3 times each) before electrocardioversion
Study: NCT04492345

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Isokinetic reeducation
Description: Conventional rehabilitation session and isokinetic during 7 weeks

Intervention type: OTHER
Group type: OTHER
Intervention: Conventional reeducation
Description: Conventional rehabilitation session during 7 weeks
Study: NCT05032768

Intervention type: RADIATION
Intervention: post-operative radiotherapy
Description: Breast cancer patients who have received reconstructive surgery will receive post-operative radiotherapy.

Intervention type: RADIATION
Intervention: post-operative radiotherapy
Description: Breast cancer patients who have received reconstructive surgery will receive post-operative radiotherapy.
Study: NCT06445309

Intervention type: OTHER
Intervention: Sensory test of functional plant-based drink
Description: Once the volunteers have been recruited, a telephone interview lasting less than 10 minutes will be carried out where what the study consists of will be explained as well as the information sheet for the participant will be read to them so that they understand what the study consists of. study. Once the necessary questions have been asked according to the inclusion criteria, if the participant enters the study, data such as name, surname, age, gender, smoker, consumer of vegetable drinks, pathologies and contact information will be collected. If the participant does not enter the study, their personal data will no longer be collected and they will be informed that according to the exclusion criteria they can no longer participate in the study. Once these data are obtained, it will be randomized using the EXCEL program.
Study: NCT06385405

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Individualized alpha frequency Transcranial Magnetic Stimulation (αTMS) Treatment
Description: The target site for alpha frequency Transcranial Magnetic Stimulation (αTMS) was identified based on alterations in alpha band spectral connectivity, which were measured using four frontal electroencephalography (EEG) channels (F1, F3, F5, FC3) subsequent to 10Hz transcranial magnetic stimulation (TMS). Alpha band spectral connectivity refers to the degree of similarity between the spectral waveforms of the alpha band across channels. The alpha frequency stimulation rate was defined as the highest spectral peak within the alpha band ranging from 7 to 13 Hz of the target channel. Each treatment cycle consisted of 20 daily sessions over a 4-week span, and stimulation was administered for 2 seconds every minute for a total duration of 20 minutes at 80% of the individual's motor threshold.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 10Hz-frequency TMS treatment over the left dorsolateral prefrontal cortex (DLPFC)
Description: Prefrontal Transcranial Magnetic Stimulation (TMS) therapy repeated daily over 4 weeks (20 sessions) is US Food and Drug Administration (FDA) approved for treating Major Depressive Disorder in adults who have not responded to prior antidepressant medications. The strongest evidence supports high-frequency treatment over the left dorsolateral prefrontal cortex (DLPFC). The common stimulation frequency is 10Hz. It is usually applied for a duration of 4 weeks, 5 days a week.
Study: NCT06503029

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Invisalign Cleaning Crystals
Description: Invisalign Cleaning Crystals are used as a cleaning method for orthodontic clear aligners. It includes Sodium Sulfate as an active ingredient.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fittey Dent Cleaning Tablet
Description: Fittey Dent Cleaning Tablet is used as a cleaning method for orthodontic clear aligners. It includes Sodium Perborate as an active ingredient.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Listeren Mouthwash
Description: Listeren Mouthwash is used as a cleaning method for orthodontic clear aligners. It includes Eucalyptol and Menthol as active ingredients.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Toothbrush and Water
Description: Toothbrush and water is used as a cleaning method for orthodontic clear aligners that as recommended by the aligner manufacturer.
Study: NCT05210296

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercises
Description: Therapeutic exercise will be applied to the elderly

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercises
Description: Therapeutic exercise will be applied to the elderly
Study: NCT05039398

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: The workplace receives dialogue and guidance during the WEA workplace inspection as per WEA standard practice.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialogue and guidance over telephone
Description: In addition to receiving dialogue and guidance during WEA workplace inspection as standard practice by the WEA, the Dialogue and guidance over telephone receives up to 2 hours of supplemental dialogue and guidance after WEA inspection with the WEA inspector. This is conducted over the telephone.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialogue and guidance at physical meeting
Description: In addition to receiving dialogue and guidance during WEA workplace inspection as standard practice by the WEA, the Dialogue and guidance at physical meeting receives up to 2 hours of supplemental dialogue and guidance after WEA inspection with the WEA inspector. This is conducted as a physical meeting.
Study: NCT04560569

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albuvirtide
Description: Long-Acting HIV-1 Fusion Inhibitor (chemically modified peptide targeting HIV-1 gp41)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albuvirtide
Description: Long-Acting HIV-1 Fusion Inhibitor (chemically modified peptide targeting HIV-1 gp41)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3BNC117 Antibody
Description: Recombinant, fully human mAb of the IgG1κ isotype that specifically binds to HIV-1 gp120

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3BNC117 Antibody
Description: Recombinant, fully human mAb of the IgG1κ isotype that specifically binds to HIV-1 gp120
Study: NCT06209671

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: INS19 CAR-T Cells
Description: INS19 CAR-T Cells, 1-2×10\^7 cells, treatment follows a lymphodepletion. Drug: Fludarabine Recommendation: 25-30 mg/m\^2/day (D-5\~D-3), determined by tumor burden at baseline. Drug: Cyclophosphamide Recommendation: 250-300 mg/m\^2/day (D-5\~D-3), determined by tumor burden at baseline.
Study: NCT06274671

Intervention type: OTHER
Intervention: Magnetic Resonance Imaging
Description: A Magnetic Resonance Imaging (duration: about 60 minutes) with research sequences for the visualization of alterations of the glymphatic system.

Intervention type: OTHER
Intervention: Magnetic Resonance Imaging
Description: A Magnetic Resonance Imaging (duration: about 60 minutes) with research sequences for the visualization of alterations of the glymphatic system.
Study: NCT05629195

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: tunneled PICC
Description: PICC catheter is inserted into the superior vena cava through the upper brachial vein by establishing a subcutaneous tunnel

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tunneled PICC
Description: PICC catheter is inserted into the superior vena cava through the upper brachial vein by establishing a subcutaneous tunnel
Study: NCT06634680

Intervention type: PROCEDURE
Intervention: Procedure: Selection of parent(mother or father) according to children preference
Description: Children will choose the parent who will accompany them.

Intervention type: PROCEDURE
Intervention: Procedure: Both parents will accompany the children.
Description: Both parents will accompany the children.
Study: NCT06115408

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dienogest 2 MG
Description: Clinical trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-acetyl cysteine
Description: Clinical trial
Study: NCT04864509

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Melatonin 10 MG
Description: Nightly dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Nightly dose
Study: NCT04823520

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TCA
Description: All patients will receive 6 sessions at 2 weeks intervals,the half face which will recieve MDA and TCA,MDA will be done before appling TCA.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TCA
Description: All patients will receive 6 sessions at 2 weeks intervals,the half face which will recieve MDA and TCA,MDA will be done before appling TCA.
Study: NCT05311098

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cryoablation
Description: Treatment of atrial fibrillation with cryoablation catheters
Study: NCT06065865

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guidance document
Description: The main intervention of interest is the guidance document, which is explained under 'Arms'. Within the treatment trajectory, that is based on the guidance document, the participants can receive a combination of NIKA, and parent and child can both get EMDR-therapy. The therapies are combined in one treatment trajectory.~NIKA consists of 5 weekly sessions during which participants are videotaped by a trained therapist. The therapist will provide personalized feedback to the parent, which is focused on reducing disrupted parenting behavior and increasing sensitive parenting behavior. EMDR is a brief trauma therapy (in this trial a maximum of six 90-min sessions for the parent and a maximum of six 60-min sessions for the child) aimed at reducing the negative load of the memories of traumatic events. Both parent and child can receive this therapy. During the weekly sessions, the participant is asked to bring the traumatic event to mind while the therapist provides a distracting task.
Study: NCT06312748

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-Citrulline
Description: 100 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-Citrulline
Description: 100 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for L-Citrulline
Description: L-Citrulline-matched Placebo tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for L-Citrulline
Description: L-Citrulline-matched Placebo tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BH4
Description: 10mg/kg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BH4
Description: 10mg/kg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for BH4
Description: BH4-matched Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for BH4
Description: BH4-matched Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: 10 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: 10 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for Atorvastatin
Description: Atorvastatin-matched Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for Atorvastatin
Description: Atorvastatin-matched Placebo
Study: NCT05074849

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A 90-minute self-care education + bi-weekly 30-minute one-on-one follow-up phone discussion
Description: A 90-minute group session to educate patients on foot self-care strategies (daily foot hygiene and cleanliness, foot protection, use of insoles and smart watch). Follow-up Care: A biweekly 30-minute one-on-one follow-up phone discussion (i.e., daily foot hygiene and cleanliness, foot protection, use of insoles and smart watch, addressing feedback and questions regarding the intervention and prevention of foot-related complications).
Study: NCT05968287

Intervention type: DIAGNOSTIC_TEST
Intervention: The Leukocyte ImmunoTest™ (LIT™)
Description: The baseline LIT scores was performed for two parallel groups. The sequential LIT score was also performed for patients with various infection conditions with/without sepsis.

Intervention type: DIAGNOSTIC_TEST
Intervention: The Leukocyte ImmunoTest™ (LIT™)
Description: The baseline LIT scores was performed for two parallel groups. The sequential LIT score was also performed for patients with various infection conditions with/without sepsis.
Study: NCT05594823

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide
Description: Subjects will be given a regimen that determines a variable daily dose of diuretic (furosemide) based on daily self-measured weights as part of the standard of care ambulatory management of chronic heart failure. Follow-up will occur at 90 days with routine bloodwork to monitor renal function.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ambulatory heart failure management with fixed dose furosemide
Description: Subjects will be prescribed a fixed daily dose of diuretic (furosemide) as part of the standard of care ambulatory management of chronic heart failure. Follow-up will occur at 90 days with routine bloodwork to monitor renal function.
Study: NCT05662410

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Three monthly injections of intravitreal aflibercept
Description: Three monthly intravitreal injection of aflibercept (2.0mg / 0.05ml) after diagnosis of pathychoroid neovasculopathy.
Study: NCT04726462

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional exercises
Description: The exercise program is planned as a function-oriented exercise program aimed at improving balance skills, increasing lower extremity muscle strength and functions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Posture exercises
Description: The exercise program was planned by focusing on posture exercises in order to increase the postural smoothness of the participants.
Study: NCT06357351

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: vestibular incision sub periosteal tunnel access ( VISTA) technique.
Description: In comparison between the two groups, the first group uses collagen membrane and the other group uses advanced PRF using the same surgical technique (VISTA)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: vestibular incision sub periosteal tunnel access ( VISTA) technique.
Description: In comparison between the two groups, the first group uses collagen membrane and the other group uses advanced PRF using the same surgical technique (VISTA)
Study: NCT05810272

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Metabolic Trial
Description: Participants will undergo a metabolic trial to assess for their anabolic response to a protein-carbohydrate meal.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Metabolic Trial
Description: Participants will undergo a metabolic trial to assess for their anabolic response to a protein-carbohydrate meal.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 15 sit-to-stands with calf raises
Description: Participants (n=10; 5F/5M) will be randomized to perform 15 sit-to-stands with calf raises every 30 minutes for the 4 hour duration between muscle biopsies
Study: NCT06486311

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: satellite implant
Description: Satellite implant is a additional holding component as a stabilizer to provide a polygonal support to distribute forces and moments on single-standing implants give the implant sufficient resistance to withstand masticatory forces or at least keep it in a stable position during an unloaded healing period to achieve stabilization and subsequent osseointegration of implants.
Study: NCT06398860

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SIOHPS
Description: The intervention is comprised of several core components such as targeted education, daily team reflections and support for systematic management. First, a two hour education will be conducted for management, HCW involved in patient safety work, safety representatives and intervention facilitators. The second core component is a short daily team reflection conducted by HCW at the unit in connection to the end of work shifts. These are standardized to support identification of situations at work related to both Safety I and II perspective for both occupational health and patient safety as well as learning. The third component includes risk assessment, planning and implementation of appropriate measures, follow up and evaluation, based in information identified in the second component. The steps in this component targets the management and should be conducted in close collaboration with HCW involved in patient safety work and the safety representatives.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wait-list
Description: No intervention
Study: NCT06236698

Intervention type: DIAGNOSTIC_TEST
Intervention: 24-hour urinary aldosterone
Description: Collect 24-hour urine from each participant and complete the detection of urinary aldosterone content.

Intervention type: DIAGNOSTIC_TEST
Intervention: 24-hour urinary aldosterone
Description: Collect 24-hour urine from each participant and complete the detection of urinary aldosterone content.
Study: NCT05364372

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Symptom assessment only
Description: Dyads will receive 12 weekly phone calls to assess symptom management.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Symptom management and lifestyle intervention
Description: Survivor and caregiver dyads will work together with a coach to establish diet and physical activity change SMART goals. Motivational interviewing based weekly coaching sessions will review symptom management and goal attainment and then enact strategies to modify goals to be more relevant and achievable.
Study: NCT06082089

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Divorce Adjustment Program (DAP)
Description: This is a brief group intervention program for divorced women. It consists of 6 sessions for participants with children and 5 sessions for participants without children. Each session lasts approximately 2.5-3 hours focusing on one of the difficulties experienced by women after divorce (i.e., self-perception, emotions and emotion regulation, social problems, family-related problems, problems with ex-spouse and children (for participants with children)). In this study, the DAP will be implemented in online format.
Study: NCT05147623

Intervention type: PROCEDURE
Intervention: Any surgery/procedure
Description: Any surgery/procedure in all adult patients that were performed in an operating room
Study: NCT05467254

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CLL1+CD33 CAR-T
Description: CLL1+CD33 CAR-T is a new type CAR-T cells therapy for patients with acute myeloid leukemia.
Study: NCT05950711

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combination use of MBCT and IV Ketamine
Description: Group with Major Depression who will receive a single dose of IV Ketamine embedded within a course of MBCT.