TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04614766

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutathera
Description: intravenous administration

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lutathera
Description: intravenous administration
Study: NCT06343922

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: oral motor facilitation technique group
Description: oral motor facilitation technique

Intervention type: OTHER
Group type: OTHER
Intervention: traditional oral motor exercises group
Description: traditional oral motor exercises
Study: NCT06034301

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medication Reminder App
Description: If the participant is randomized to the intervention group, they will:~1. receive a brief education session and be handed a flyer about the importance of medication adherence.~2. get training on how to use the medication reminder app and participant will be given a user guide on how to use the app~3. demonstrate their understanding on an iPad using the teach back method~4. install and set up the medication reminder app on their phone~5. receive a MEMS cap and be given instructions on how to use it with their blood pressure medication. Study team members will use a participant ID to log into the MEMS cap application; no identifiable information will be entered.
Study: NCT06649656

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2252 injection
Description: TQB2252 injection is a compound preparation of TQB2223 monoclonal antibody (LAG-3) and penpulimab (PD-1), with a specification of 300mg TQB2223 monoclonal antibody and 100mg (20ml) penpulimab per bottle.
Study: NCT06649864

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Autologous adipose derived mesenchymal stromal cells (AMSC)
Description: Adipose derived autologous mesenchymal stromal cells; \[\~500,000 cells/cm2\] will be applied once to the biliary anastomosis using approximately 3-5 million cells in 5ml Lactated Ringer solution.
Study: NCT05969626

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 5-dose group of test vaccine
Description: Subjects will be vaccinated on days 0, 3, 7, 14, and 28

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: 5-dose group of control vaccine
Description: Subjects will be vaccinated on days 0, 3, 7, 14, and 28

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4-dose A group of test vaccine
Description: Subjects will be vaccinated on days 0, 3, 7, 14

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4-dose B group of test vaccine
Description: Subjects will be vaccinated on days 0, 3, 7, 28
Study: NCT04821726

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Drug eluting balloon (Vmoky)
Description: Use Vmoky Drug Eluting Balloon to treat patients with symptomatic intracranial atherosclerosis stenosis
Study: NCT00012792

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Exercise Training
Study: NCT06403176

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05442229

Intervention type: OTHER
Intervention: establish a new Chinese children's speech and language norm
Description: 1063 normally developing children and 96 abnormally developing children will be retrospectively enrolled from the medical records of stratified, randomly selected centers. A total of 4137 children with normal development and 448 children with abnormal development aged from 2 to 6 years old will be selected from 11 hospitals in China by multi-center, stratified, unequal proportion random sampling and face-to-face survey. Children's speech and language development was assessed by the Speech and Language Development Scale for children aged 2 to 6, compiled by the Linguistics and Language Research Centre of the Education University of Hong Kong.

Intervention type: OTHER
Intervention: establish a new Chinese children's speech and language norm
Description: 1063 normally developing children and 96 abnormally developing children will be retrospectively enrolled from the medical records of stratified, randomly selected centers. A total of 4137 children with normal development and 448 children with abnormal development aged from 2 to 6 years old will be selected from 11 hospitals in China by multi-center, stratified, unequal proportion random sampling and face-to-face survey. Children's speech and language development was assessed by the Speech and Language Development Scale for children aged 2 to 6, compiled by the Linguistics and Language Research Centre of the Education University of Hong Kong.
Study: NCT05754255

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasal Cannula
Description: A nasal cannula is a medical device to provide supplemental oxygen therapy to people who have lower oxygen levels. There are two types of nasal cannulas: low flow and high flow.~The device has two prongs and sits below the nose. The two prongs deliver oxygen directly into your nostrils.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasal Positive Airway Pressure System
Description: Positive airway pressure (PAP) treatment uses a machine to pump air under pressure into the airway of the lungs. This helps keep the windpipe open during sleep. The forced air delivered by CPAP (continuous positive airway pressure) prevents episodes of airway collapse that block the breathing in people with obstructive sleep apnea and other breathing problems.
Study: NCT05782933

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab combined with or without cyclosporine

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Modified Ponticelli regimen
Description: Corticosteroid and cyclophosphamide
Study: NCT05227391

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Oral Letrozole
Description: Oral Letrozole at a dose of 2.5mg daily will be started on days 3-5 of the menstrual cycle and will be continued for 5 days.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Oral estradiol valerate
Description: Oral estradiol valerate at a dose of 3mg twice daily will be started on days 3-5 of the menstrual cycle.
Study: NCT05173155

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: surgical approach
Description: Comparison of short-term outcomes (patient mobility, quality of life, function, pain, and safety parameters) for the direct anterior approach and Lateral approach for hemiarthroplasty for patients who have experienced a femoral-neck hip fracture.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: surgical approach
Description: Comparison of short-term outcomes (patient mobility, quality of life, function, pain, and safety parameters) for the direct anterior approach and Lateral approach for hemiarthroplasty for patients who have experienced a femoral-neck hip fracture.
Study: NCT04614766

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azedra
Description: intravenous administration
Study: NCT06158737

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JS010 injection
Description: This study adopts a dose escalation design with six preset dose levels, namely 3mg, 30mg, 150mg, 300mg,600mg, 900mg, single subcutaneous injection. A total of 48 healthy subjects were enrolled in the experiment, 8 in each group.They were randomly assigned to receive JS010 injection and matching placebo in a ratio of 3:1. In accordance with the dose-escalation principle,Starting from the lowest initial dose, increasing to the higher dose and proceeding in sequence. Each subject can receive only one dose Level of single subcutaneous administration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: This study adopts a dose escalation design with six preset dose levels, namely 3mg, 30mg, 150mg, 300mg,600mg, 900mg, single subcutaneous injection. A total of 48 healthy subjects were enrolled in the experiment, 8 in each group.They were randomly assigned to receive JS010 injection and matching placebo in a ratio of 3:1. In accordance with the dose-escalation principle,Starting from the lowest initial dose, increasing to the higher dose and proceeding in sequence. Each subject can receive only one dose Level of single subcutaneous administration.
Study: NCT04902859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clonidine Oral Liquid Product
Description: Clonidine prepared from pharmacy with 20 mcg/ml concentration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clonidine Oral Liquid Product
Description: Clonidine prepared from pharmacy with 20 mcg/ml concentration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sterile water
Description: Sterile water used as placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sterile water
Description: Sterile water used as placebo
Study: NCT04900103

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ITV-Pal
Description: Use of new technologies for volunteering
Study: NCT05889650

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: External Lumbar drainage
Description: ELD @ 15 or 20mmHg based on intervention arm with maximum of 10ml/hour drainage
Study: NCT05734885

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Back and Sacral massage massage application
Description: Massage will be applied to the pregnant woman in the position preferred by the pregnant woman. Circular movements are applied to the sacrum with the thumb. Pressure is applied to both sides of the spinal cord with the thumb. The thumb is moved towards the hip of the pregnant woman at 1.5 cm intervals, starting from the lower part of the pelvis and the sacrum. The palm is placed in direct contact with the mother's sacrum and pressure is applıed. The massage is completed by making a bunch of flowers from the sacrum upwards, towards the shoulder and around it.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Back and Sacral massage massage application
Description: Massage will be applied to the pregnant woman in the position preferred by the pregnant woman. Circular movements are applied to the sacrum with the thumb. Pressure is applied to both sides of the spinal cord with the thumb. The thumb is moved towards the hip of the pregnant woman at 1.5 cm intervals, starting from the lower part of the pelvis and the sacrum. The palm is placed in direct contact with the mother's sacrum and pressure is applıed. The massage is completed by making a bunch of flowers from the sacrum upwards, towards the shoulder and around it.
Study: NCT05398328

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active metal appliance
Description: fixed metal labial orthodontic appliance MBT 0.022'' slot

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active metal appliance
Description: fixed metal labial orthodontic appliance MBT 0.022'' slot

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active esthetic appliance
Description: fixed ceramic labial orthodontic appliance MBT 0.022'' slot
Study: NCT06383039

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: Evaluations will be made in the presence of a physiotherapist. Individuals; For demographic information~• Demographic Information Form~For Static Balance Evaluation:~* Wii-Fit~* Balance Error Scoring System~For Dynamic Balance Assessment:~* Star Balance Test~* Timed Get Up and Go Test

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: Evaluations will be made in the presence of a physiotherapist. Individuals; For demographic information~• Demographic Information Form~For Static Balance Evaluation:~* Wii-Fit~* Balance Error Scoring System~For Dynamic Balance Assessment:~* Star Balance Test~* Timed Get Up and Go Test

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: Evaluations will be made in the presence of a physiotherapist. Individuals; For demographic information~• Demographic Information Form~For Static Balance Evaluation:~* Wii-Fit~* Balance Error Scoring System~For Dynamic Balance Assessment:~* Star Balance Test~* Timed Get Up and Go Test
Study: NCT05941026

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structured education
Description: The educational content of the research was created by the researcher in line with the literature and expert opinions and covers the following topics.~Educational subjects~1. Culture and Concepts Related to Culture~2. Culture/Cultural Characteristics and Cultural Elements in Terms of Social Structure~3. Cultural Factors Affecting Health and Disease~4. Concepts and Practices Related to the Field of Study~The training is an online training and continued via video conference, and a session invitation was sent to the participants before each session. In addition, after the training, brochures containing the training topics of each week were prepared and delivered to the participants. The trainings were conducted by the researcher in a total of four sessions (each session 20 minutes) once a week during the training process. During the training, the questions of the participants were answered.
Study: NCT06038591

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Tight
Description: The sleep intervention focuses on enhancing young children's sleep by providing parents with behavioral strategies and support. Interventionists will work with parents on establishing consistent soothing bedtime routines; behavioral regulation to manage bedtime resistance and nighttime wakings; goal setting, problem solving, and action planning; self-monitoring via daily sleep logs; and stimulus control of child's sleep environment.
Study: NCT05398328

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active esthetic appliance
Description: fixed ceramic labial orthodontic appliance MBT 0.022'' slot

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: retention fixed appliance
Description: fixed lingual metal retention appliance

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: retention fixed appliance
Description: fixed lingual metal retention appliance

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: retention removable appliance
Description: removable clear termoplastic retention appliance

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: retention removable appliance
Description: removable clear termoplastic retention appliance
Study: NCT06144502

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5Ways@School
Description: The 5Ways@School intervention is a teaching material consisting of five elements; Take notice, Be active, Keep Learning, Connect, and Give. The intervention will be given in an ordinary classroom setting by the class' main teacher in two school hours of 45 minutes each week for six consecutive weeks, i.e., a total of 12 school hours. The teaching sessions will consist of presentations of the five elements, videos, reflection exercises, focused group discussions, creative group work, and giving the pupils small challenges to practice what they have learned between the weekly sessions.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: 5Ways@School
Description: The 5Ways@School intervention is a teaching material consisting of five elements; Take notice, Be active, Keep Learning, Connect, and Give. The intervention will be given in an ordinary classroom setting by the class' main teacher in two school hours of 45 minutes each week for six consecutive weeks, i.e., a total of 12 school hours. The teaching sessions will consist of presentations of the five elements, videos, reflection exercises, focused group discussions, creative group work, and giving the pupils small challenges to practice what they have learned between the weekly sessions.
Study: NCT05769894

Intervention type: OTHER
Intervention: No intervention given
Description: No intervention is planned. Blood samples will be taken at different stages.

Intervention type: OTHER
Intervention: No intervention given
Description: No intervention is planned. Blood samples will be taken at different stages.

Intervention type: OTHER
Intervention: No intervention given
Description: No intervention is planned. Blood samples will be taken at different stages.

Intervention type: OTHER
Intervention: No intervention given
Description: No intervention is planned. Blood samples will be taken at different stages.

Intervention type: OTHER
Intervention: No intervention given
Description: No intervention is planned. Blood samples will be taken at different stages.
Study: NCT05303805

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane
Description: Topical application of 1 mL sevoflurane per 1 cm2 ulcer area once or two times daily.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Cyteal
Description: Rinsing and cleaning of ulcer.
Study: NCT05962905

Intervention type: OTHER
Intervention: Blood sample
Description: During the standard of care interventional or diagnostic cardiac catheterization, paired arterial and venous blood samples will be obtained. The venous sample will be obtained from 2 cm superior to the clavicle, which is beyond standard of care during the routine cardiac catheterization

Intervention type: OTHER
Intervention: Blood sample
Description: During the standard of care interventional or diagnostic cardiac catheterization, paired arterial and venous blood samples will be obtained. The venous sample will be obtained from 2 cm superior to the clavicle, which is beyond standard of care during the routine cardiac catheterization

Intervention type: DEVICE
Intervention: INVOS monitoring
Description: During the standard of care interventional or diagnostic cardiac catheterization, INVOS monitoring will be used. INVOS™ regional oxygen saturation (rSO2) values will be compared to the calculated global field saturation of cerebral tissue determined from blood sample co-oximetry.

Intervention type: DEVICE
Intervention: INVOS monitoring
Description: During the standard of care interventional or diagnostic cardiac catheterization, INVOS monitoring will be used. INVOS™ regional oxygen saturation (rSO2) values will be compared to the calculated global field saturation of cerebral tissue determined from blood sample co-oximetry.
Study: NCT04803929

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-ILT3 CAR-T
Description: Autologous T cells genetically modified with anti-ILT3 CAR
Study: NCT04925297

Intervention type: OTHER
Intervention: No intervention
Description: No intervention will be given

Intervention type: OTHER
Intervention: No intervention
Description: No intervention will be given
Study: NCT05234515

Intervention type: DIAGNOSTIC_TEST
Intervention: Microbiology swab
Description: Patients will have swabs taken from the nose, mouth, umbilical skin, groin skin, fistula(e), stoma(s) and vascular access device prior to surgery. Patients will be followed for 90 days postoperatively for surgical site infection (SSI) as defined by the centre for disease control (CDC) criteria 2021. Patients who develop an SSI will have both preoperative and postoperative samples sent for genome sequencing.

Intervention type: OTHER
Intervention: Questionnaire
Description: Patients will complete baseline preoperative questionnaires which will be repeated at 30 days and 90 days. These will evaluate generic and wound specific quality of life as well as decision conflict/decision regret.
Study: NCT04354623

Intervention type: OTHER
Intervention: A 6-minute walk test
Description: Each subject will perform a 6-minute walk test during which gait assessment will be obtained from the APDM system (Portland, OR). In addition there will be four video cameras (on the front, back and sides) that will measure raw video data for our gait analysis. The camera does not record any facial data (in fact, 'deepfake' software in the system deletes all facial details) and the patient's movements are converted to a 'stick figure' prior to being saved in the system.

Intervention type: OTHER
Intervention: A 6-minute walk test
Description: Each subject will perform a 6-minute walk test during which gait assessment will be obtained from the APDM system (Portland, OR). In addition there will be four video cameras (on the front, back and sides) that will measure raw video data for our gait analysis. The camera does not record any facial data (in fact, 'deepfake' software in the system deletes all facial details) and the patient's movements are converted to a 'stick figure' prior to being saved in the system.
Study: NCT06154837

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3862995B
Description: GSK3862995B will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3862995B
Description: GSK3862995B will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered.
Study: NCT06489886

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Chicken
Description: This arm will be given a meal of 100 grams (\~32g of protein) boneless-skinless convential chicken breast meat together with 250mL of water

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Regenerative Chicken
Description: This arm will be given a meal of 100 grams (\~32g of protein) boneless-skinless regenerative chicken breast meat together with 250mL of water
Study: NCT05689385

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eHealth-based cardiac rehabilitation
Description: The 12-wk case manager-led eHCR program includes:~1. Individualized exercise prescription according to the results of cardiopulmonary exercise test.~2. At least one session of in-person physical therapy to familiarize participants with the process of exercise training before the initiation of telerehabilitation.~3. Telerehabilitation: a 30-minute moderate aerobic exercise training with remote monitoring and instruction using video conferencing. (Frequency: twice per week in the first 4 weeks, once per week in the 5th-8th week, once every 2 weeks in the 9th-12th week)~4. Additional self-exercise to achieve the target volume of 150-minute moderate aerobic exercise and 2 sessions of resistance training per week.~5. Patient education for secondary prevention delivered regularly via a communication app on the smartphone.~6. Weekly follow-up call from a case manager via phone call or communication app.
Study: NCT06300554

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Healthy Minds Program App
Description: freely available well-being app
Study: NCT06073925

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: VIT D
Description: 50000 IU per week of VIT D

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: VIT D
Description: 50000 IU per week of VIT D
Study: NCT04630405

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Wright jet nebulizer
Description: Roxon Medi-Tech, Montreal, QC, Canada

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Aerogen Solo
Description: Aerogen Ltd., Galway, Ireland
Study: NCT05166083

Intervention type: OTHER
Intervention: Testosterone Hormon Therapy
Description: Testosterone isocaproate, ... ml, 8 doses, once per 21 days