TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06384963

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Atrial pacing with respiratory sinus arrhythmia (RSA) variability
Description: The intervention in this study is a modification of the pacing output from a standard external pacemaker such that it will approximate the RSA variation found in healthy subjects. A pacemaker (PACE204, Osypka Medical AG), similar to those currently in common use in post-CABG patients, will be adapted to receive an additional input signal based on the respiratory signal (Ceryx device). The respiration signal will be combined with the ECG signal to determine the appropriate pacing interval. The pacing impulse will be delivered by the pacemaker unit.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Monotonic right atrial overdrive pacing
Description: Pacing is delivered by a PACE204 pacemaker (Osypka Medical AG) delivering standard monotonic right atrial pacing
Study: NCT06132789

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried
Description: This vaccine（1.0ml） is produced by Ab\&b Biotechnology Co., Ltd.JS. Subjects will receive the Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried vaccinated by intramuscular injection.
Study: NCT05381844

Intervention type: OTHER
Intervention: Blood sampling
Description: 30 ml blood sampling for virological research

Intervention type: OTHER
Intervention: Blood sampling
Description: 30 ml blood sampling for virological research
Study: NCT06132789

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried
Description: This vaccine（1.0ml） is produced by Ab\&b Biotechnology Co., Ltd.JS. Subjects will receive the Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried vaccinated by intramuscular injection.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried
Description: This vaccine（1.0ml） is produced by Ab\&b Biotechnology Co., Ltd.JS. Subjects will receive the Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried vaccinated by intramuscular injection.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried
Description: This vaccine（1.0ml） is produced by Ab\&b Biotechnology Co., Ltd.JS. Subjects will receive the Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried vaccinated by intramuscular injection.
Study: NCT06698042

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab (+) Berahyaluronidase alfa
Description: Administered subcutaneously on Day 1 of each cycle

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pembrolizumab
Description: Administered intravenously on Day 1 of each cycle
Study: NCT05039307

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational and motivational strategy
Description: The intervention will focus on the following topics A) Healthy diet: food pyramid, a healthy plate distribution, type of carbohydrates and fats, healthy cooking techniques and healthy oils. B) Physical activity: definition, types of physical activity, advantages and benefits, examples, active physical activity sessions. C) Weight control: strategies, benefits and healthy weight gain during pregnancy. D) Knowledge and awareness of T2DM and GDM: definition, prevention, management and complications. These topics will be delivered through individualized education, group sessions and focus groups. Participants will be provided with printed material at baseline and also during the individual education sessions at the household containing a brief summary of the topics covered. The motivational components of goal setting and the use of a pedometer will be incorporated explained during the individual education sessions. The intervention will be primarily delivered by trained peer educators.
Study: NCT06736236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inspiratory muscle warm-up
Description: This study will use a respiratory muscle warm-up protocol set at 40% of the maximal inspiratory pressure (MIP) using the POWERbreath® device, as this intensity has been shown to optimally stimulate respiratory muscles. The protocol involves two sets of 30 breaths with a 60-second rest between sets, performed with participants sitting and using a nose clip. Participants will be trained in this technique during the familiarization session and monitored throughout the tests to ensure proper execution.

Intervention type: OTHER
Group type: OTHER
Intervention: General warm-up (Control)
Description: The general warm-up (Control) protocol will include exercises such as running and dynamic, active, and passive movements tailored to the diverse sports disciplines in the study. These movements will follow the principles of elevation, activation, and mobilization, focusing on increasing mobility from the arms and shoulders to the lower back and legs. Each session will involve demonstrations emphasizing proper technique and speed, with participants completing a consistent number of repetitions. Researchers will monitor participants closely to ensure correct form and execution throughout the intervention.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Inspiratory muscle warm-up placebo (IMW %15)
Description: The respiratory muscle warm-up protocol will be conducted at 15% of maximal inspiratory pressure (MIP) using the POWERbreath® device. This placebo protocol will involve two sets of 30 breaths, separated by a 60-second rest, with participants seated and wearing a nose clip. Training for the technique will occur during a familiarization session, and participants will be observed during tests to ensure proper execution. The purpose of this protocol is to serve as a placebo, masking the actual aim of the study to enhance data reliability.
Study: NCT06748469

Intervention type: PROCEDURE
Intervention: The duration of the intervention will be 240 seconds
Description: Dorsal Root Ganglion pulsed radiofrequency 240sec

Intervention type: PROCEDURE
Intervention: Dorsal Root Ganglion pulsed radiofrequency 480sec
Description: The duration of the intervention will be 480 seconds
Study: NCT06750289

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: ICS-LABA
Description: ICS-LABA inhalation

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: ICS-LABA
Description: ICS-LABA inhalation

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: benralizumab
Description: Benralizumab. SC injection.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Placebo for Benralizumab
Description: Placebo for Benralizumab (aka, placebo). SC injection.
Study: NCT06748430

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Grape variety control
Description: Reference grape variety

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Grape variety 1
Description: First grape variety to evaluate

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Grape variety 2
Description: Second grape variety to evaluate
Study: NCT06749145

Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Portable 1-lead electrocardiogram
Description: Portable 1-lead electrocardiogram (ECG) performed with the FDA-approved AliveCor KardiaMobile device.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Portable 1-lead electrocardiogram
Description: Portable 1-lead electrocardiogram (ECG) performed with the FDA-approved AliveCor KardiaMobile device.

Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Point-of-care ultrasound
Description: Point-of-care ultrasound performed with the FDA-approved Butterfly iQ device.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Point-of-care ultrasound
Description: Point-of-care ultrasound performed with the FDA-approved Butterfly iQ device.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AI-ECG risk algorithm
Description: Artificial intelligence (AI) risk algorithm for aortic stenosis using a 1-lead electrocardiogram

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AI-POCUS
Description: Artificial intelligence (AI) risk algorithm for aortic stenosis using cardiac ultrasound plax videos.
Study: NCT06748573

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SafeGuard FocusTM compression bandage
Description: If randomized to the study group, The study device was applied immediately after pocket closure using following steps:~* Preparation: cleaning wound and surrounding area.~* Placement: application of isobetadine gauze and transparent bandage. Study device placement at the level of the pocket.~* Applying compression: inflation of 60ml of air. If oozing persisted 5ml increments were added (maximum of 120ml) until oozing stopped.~The study device was gradually deflated by removal of 20ml of air every 2 hours. When oozing occurred 5ml increments were added until oozing stopped. When all air was deflated the study device was left in deflated mode and changed by conventional bandage at discharge.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional bandage
Description: If randomized to the control group, compressive bandage was applied immediately after pocket closure. The bandage was removed after 6 hours and changed by conventional bandage.
Study: NCT06749275

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 5,000 ppm fluoride toothpaste
Description: In group 1, toothbrushing with toothpaste of 5,000 ppm of fluoride twice per day for two minutes, after breakfast and before bedtime. Participants will be also instructed not to rinse with water after brushing and to only eliminate the excess of the dentifrice by spitting out. The amount of toothpaste to be used had to be about the size of a pea.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 22,600 ppm fluoride varnish
Description: The application protocol of 5% fluoride varnish will be used together with the 1,450 ppm paste with the same protocol of the group 1: toothbrushing with toothpaste of 1.450 ppm of fluoride twice per day for two minutes, after breakfast and before bedtime. Participants will be also instructed not to rinse with water after brushing and to only eliminate the excess of the dentifrice by spitting out. The amount of toothpaste to be used had to be about the size of a pea.
Study: NCT06297317

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound measurement of triceps surae muscle-tendon architecture
Description: The resting plantar-flexors MTU architecture assessment was performed using a conventional B-mode and extended-field-of-view (EFOV) ultrasound imaging. Achille tendon cross-sectionnal area, Medial gastrocnemius thickness, pennation angle, fascicle length and muscle length were collected on the dominant lower limb.
Study: NCT06038214

Intervention type: OTHER
Intervention: core exercises
Description: 1.5 minutes walking 2. Stretching exercise~* hallowing in supine and side lying position~* Bracing in supine and side lying position~* Bracing on the prone and forearms~* Bracing in the crawling position~* Bracing in laptop, half-lap and standing position~* Heel slide exercise~* Bridge building exercise~* Unilateral limb flexion exercise in crawling position~* Reciprocal heel slide exercise in supine position~* Bilateral lower extremity lifting exercise~* Unilateral lower extremity flexion in bridging position~* Side bridging exercise with knees extended~* Unilateral lower extremity extension in crawling position~* Contralateral lower and upper extremity lift in the crawling position~* Straight and oblique trunk flexion~* Straight and oblique trunk flexion with hip and knee flexed to 90°~* bracing on the ball~* squat~* bracing while walking

Intervention type: OTHER
Intervention: home exercises
Description: Right and left rotation of the head~* lateral flexion of the head~* Flexion and extension of the head~* Stretching the neck extensors~* pectoral stretch~* Stretching the hip extensors~* Hamstrig stretching~* Stretching the lumbar extensors~* Abdominal strengthening~* bridging~* Hip abduction strengthening~* hip extension strengthening~* Upper extremity resistant flexion~* Upper extremity resistant abduction~* Upper extremity relaxation exercise~* Capsule stretching~* Stretching the hip flexors~* Stretching the lower extremity adductors~* relaxation exercise
Study: NCT06749275

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 38% SDF
Description: The application protocol of 38% SDF annually will be used together with the 1,450 ppm paste with the same protocol of the group 2: toothbrushing with toothpaste of 1.450 ppm of fluoride twice per day for two minutes, after breakfast and before bedtime. Participants will be also instructed not to rinse with water after brushing and to only eliminate the excess of the dentifrice by spitting out. The amount of toothpaste to be used had to be about the size of a pea.
Study: NCT06750211

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: METs
Description: * Hot pack for 10 minutes.~* Neck isometrics with 10 second hold.~* Each series of neck isometrics strengthening exercises had three movements including cervical flexion, cervical extension and cervical side flexion.~* Muscle energy technique protocol: The individual was in a position of supine. The therapist was at the edge of bed, near the participants head. the therapist positioned the joint at the point of beginning range of motion resistance when performing a given movement. When the therapist felt restriction, positioned the cervical spine in that region and apply the resistive force. Patient was instructed to contract isometrically for five seconds without exceeding the therapist force. thereafter, therapist counterforce gradually reduced and patient was asked to relaxed. Therapist move the joint into new point of barrier and same protocol repeated three times.~Patient came thrice per week for a total of 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MCTE along with METs
Description: ▪ Hot pack for 10 minutes.~* Neck isometrics with 10 second hold.~* Each series of neck isometrics strengthening exercises had three movements including cervical flexion, cervical extension and cervical side flexion.~* After it was treated with motor control therapeutic exercises together with muscle energy technique. Motor control therapeutic exercises included cranio-cervical flexor exercises, cranio-cervical extensor exercises, co contraction of flexor and extensor and synergy exercise for strengthening deep neck flexor. Exercises were performed in three sets with 10 repetitions with an approximate duration of 10 to 20 minutes. They were advised to perform at home once in a day, five times in a week for a duration of 4 weeks.~All exercises were performed three times per week for total of 4 weeks.
Study: NCT06750354

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: papworth technique
Description: For Group A: The Papworth breathing technique consists of a series of diaphragmatic breathing and relaxation exercises, and teaches patients which muscles to use when breathing and how to avoid breathing too or too fast by emphasizing nose breathing. The technique is altered to suit activity; this allows the technique to be integrated by patients into their everyday lives with subsequent improvements in quality of life.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: aerobic training
Description: Aerobic training exercises are any activities that raise heart rate and make breathing somewhat harder. The activity you are doing must be constant and continuous. Examples of aerobic activities are~Walking or hiking Jogging or running Biking Swimming Rowing In-line skating Cross-country skiing Exercising on a stair-climber or elliptical machine

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: aerobic training
Description: Aerobic training exercises are any activities that raise heart rate and make breathing somewhat harder. The activity you are doing must be constant and continuous. Examples of aerobic activities are~Walking or hiking Jogging or running Biking Swimming Rowing In-line skating Cross-country skiing Exercising on a stair-climber or elliptical machine
Study: NCT06206720

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide for Suspension
Description: 15 mg/kg BID group: 15 subjects will receive Deuremidevir Hydrobromide for Suspension once every 12 hours, total 10 times.~20 mg/kg BID group: 15 subjects will receive Deuremidevir Hydrobromide for Suspension once every 12 hours, total 10 times.~20 mg/kg TID group: 15 subjects will receive Deuremidevir Hydrobromide for Suspension 3 times every day, total 15 times.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 15 mg/kg BID group: 5 subjects will receive placebo once every 12 hours, total 10 times.~20 mg/kg BID group: 5 subjects will receive placebo once every 12 hours, total 10 times.~20 mg/kg TID group: 5 subjects will receive placebo 3 times every day, total 15 times.
Study: NCT06308315

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rhythmic balance visual auditory exercise + Routine physical therapy
Description: 5 minute warm-up activities.~Bal-A-Vis-X training includes:~1. Ball Rectangle; A and B hold one ball in each hand, simultaneously bounce right balls to patient left hand; while balls bounce, clap left balls on right hand; catch patient ball with left hand; continue pattern. Bounces must be simultaneous. (10 minutes)~2. Ball rectangle in which one hand has to toss a ball to a partner and the other hand catch an incoming bag from the partner and 2 ball drop/pass/catch, two-foot jumping forward, tandem walking on ground. (10 minutes)~Routine Physical therapy treatment includes:~Range of Motion exercises, Stretching, Strength, balance training for 15 minutes~5 minute cool-down activities.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strength Training + Routine Physical Therapy
Description: The expert managed sessions based on:~5 minute warm-up activities. 5 minute cool-down activities. Strength training includes 5 tasks for 20 minutes~1. core strengthening,~2. upper and lower limbs strength in both static positions as well as with dynamic movements~3. standing long jump,~4. knee push-ups,~5. sit-ups~Routine Physical therapy treatment will be given for 15 minutes.~It includes:~Range of Motion exercises, Stretching, Strength, balance training.
Study: NCT04860466

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CC-96673
Description: IV Infusion
Study: NCT06211296

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Shortcut
Description: Splitting bioprosthetic aortic valve leaflets
Study: NCT05317936

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirtobrutinib
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: GIven by PO
Study: NCT05020457

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SI-B001
Description: SI-B001 is administered by intravenous drip once weekly (QW). 120 min ± 10 min after the first intravenous drip, if the infusion reaction is tolerable during the first dose, the subsequent infusion can be completed within 60-120 min (unless agreed or required by the investigator, the infusion time can be extended), if SI-B001 and chemotherapy are used on the same day, the infusion of chemotherapeutic drugs should be continued after the completion of SI-B001 infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SI-B001
Description: SI-B001 is administered by intravenous drip once weekly (QW). 120 min ± 10 min after the first intravenous drip, if the infusion reaction is tolerable during the first dose, the subsequent infusion can be completed within 60-120 min (unless agreed or required by the investigator, the infusion time can be extended), if SI-B001 and chemotherapy are used on the same day, the infusion of chemotherapeutic drugs should be continued after the completion of SI-B001 infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SI-B001
Description: SI-B001 is administered by intravenous drip once weekly (QW). 120 min ± 10 min after the first intravenous drip, if the infusion reaction is tolerable during the first dose, the subsequent infusion can be completed within 60-120 min (unless agreed or required by the investigator, the infusion time can be extended), if SI-B001 and chemotherapy are used on the same day, the infusion of chemotherapeutic drugs should be continued after the completion of SI-B001 infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AP or TP
Description: AP or TP should be administered immediately after SI-B001 is completed. The administration of AP or TP should refer to the drug instructions and standard usage.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Docetaxel should be administered immediately after SI-B001 is completed. The administration of Docetaxel should refer to the drug instructions and standard usage.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Docetaxel should be administered immediately after SI-B001 is completed. The administration of Docetaxel should refer to the drug instructions and standard usage.
Study: NCT06266689

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Personalized Diet Information
Description: These participants will receive a report detailing their genomic food data based on the investigators' DNA metabarcoding technique in addition to standard dietary guidance to see if receiving the report modifies what they choose to feed their infant.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Personalized Diet Information
Description: These participants will receive a report detailing their genomic food data based on the investigators' DNA metabarcoding technique in addition to standard dietary guidance to see if receiving the report modifies what they choose to feed their infant.
Study: NCT06049212

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sacituzumab tirumotecan
Description: Sacituzumab tirumotecan injection powder for intravenous (IV) infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sacituzumab tirumotecan
Description: Sacituzumab tirumotecan injection powder for intravenous (IV) infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab solution for IV infusion.