TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06313515

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous Spinal Cord Stimulation
Description: Non-invasive electrical stimulation of the spinal cord over the skin

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Spinal Cord Stimulation
Description: Non-invasive electrical stimulation of the spinal cord over the skin

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Arm-crank bike exercise
Description: Exercise using an arm-bike to target cardiovascular functioning.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Arm-crank bike exercise
Description: Exercise using an arm-bike to target cardiovascular functioning.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Stimulation
Description: Non-invasive electrical stimulation of a lower extremity muscle group over the skin.
Study: NCT04447807

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Metacognitive Training
Description: MCT is a structured, interactive approach that addresses cognitive biases, social cognition, and self-esteem. This study will conducted this intervention using group format, on a weekly basis, with duration of 9 weeks total.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as Usual
Description: Patients will continue to receive medical attention in the Bipolar Disorder Program -PROMAN- part of the University of São Paulo Medical School.
Study: NCT05377996

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XMT-1660
Description: XMT-1660 will be administered through a vein in your arm or port catheter (intravenously)
Study: NCT05853497

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-Component Weight Loss Intervention
Description: The intervention group will receive weekly 1-on-1 health coaching with a very-low calorie nutrition plan prior to total knee replacement and a conventional weight maintenance nutrition plan after surgery.
Study: NCT06060899

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pneumoperitoneum 14mmHg
Description: Performing surgery in 14mmHg pneumoperitoneum pressure

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pneumoperitoneum 10mmHg
Description: Performing surgery in 10mmHg pneumoperitoneum pressure
Study: NCT06578468

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: End-tidal oxygen monitor
Description: The only additional equipment required for this study is the Philips™ IntelliVue G7m Gas Analyser Module 866173. This provides a non-dispersive infrared measurement of respiratory gases and a paramagnetic measurement of oxygen. At Lincoln Medical Center, the gas analyser used will be a Philips G5 gas analyser connected to a Philips Intellivue MP 70. At the University of New Mexico Medical Center, the Masimo root monitor is used.~The gas analysers produce display waves for O2 and CO2, together with numerics for end-tidal values for O2 and CO2 and to our knowledge, there are no differences in values between the various devices used. The gas sampling occurs through a side-stream sampling tube at a rate of 200ml/min ±20 ml/min, which is either obtained from a nasal cannula in the spontaneously breathing patient or a sidestream line if connected to a BVM.
Study: NCT05538741

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bolus of remimazolam
Description: 0.19-0.25 mg/kg for 60-80 years old 0.14-0.19 mg/kg for \>80 years old

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Continuous infusion of remimazolam
Description: 12 mg/kg/hr until loss of consciousness
Study: NCT06053268

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Headspace
Description: The intervention will be delivered via the Headspace mobile application. The basic application program includes daily 10-minute sessions in guided mindfulness meditation that include mindful breathing, body awareness, emotion and thought recognition, and attentional control
Study: NCT06510153

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Environmental Music Therapy
Description: The music will consist of improvised music at a slow to moderate tempo, using free-flowing melodies, and simple chord progressions, focusing on creating moments of tension and resolution during approximately 20 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pre-recorded music
Description: The protocol for pre-recorded music is the same as for EMT.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard care only
Description: Standard care in the emergency room waiting room as provided by each hospital without being exposed to EMT or pre-recorded music.
Study: NCT06229444

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ILI Predictive Alerts, Reactive Content, and Proactive Content
Description: Participants receive ILI-related education, feedback, and opportunities to self-monitor ILI symptoms, in addition they also receive alerts about potential ILI illness, and reactive and personalized content about protective health behaviors.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ILI Predictive Alerts, Reactive Content
Description: Participants receive alerts about potential ILI illness, and reactive and personalized content about protective health behaviors.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Proactive Content
Description: Participants receive ILI-related education, feedback, and opportunities to self-monitor ILI symptoms.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: No Intervention
Description: Participants will not receive predictive alerts or reactive content after reporting symptoms or proactive IILI-related health educational content
Study: NCT05202119

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial direct current stimulation
Description: Transcranial direct current stimulation (tDCS) a non-invasive brain stimulation technique where a weak direct current (2 mA) is applied on the scalp through electrodes. The current modulates the underlying neural activity. The sessions are 30 minutes, 3-5 time a week.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Transcranial direct current stimulation
Description: To blind the participants of the stimulation, a standardized sham protocol is used where the current ramped up and then down breifly in the beginning and end of each session to simulate active stimulation.
Study: NCT04979546

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intensive Use of Patient Reported Outcome Measures and Open PROM Availability to Treating Neurologist
Description: Baseline, 6 months, and 12 months administration of HADS, EQ5D, MFIS, PDDS, PHQ-9 questionnaires in addition to Open ended text response to (limit 280 characters) What are the top 3 things you would like your MS Neurologist to know about you right now?~Additionally, the treating neurologist will be prompted to view the text response to the 3-item prompt in addition to the PROM questionnaire scores for participants in the interventional group.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative Use of Patient Reported Outcome Measures and Blinded PROM Availability to Treating Neurologist
Description: Baseline and 12 months administration of HADS, EQ5D, MFIS, PDDS, PHQ-9 questionnaires in addition to Open ended text response to (limit 280 characters) What are the top 3 things you would like your MS Neurologist to know about you right now?~Additionally, the treating neurologist will only be prompted to view the text response to the 3-item prompt, and will not be able to access the PROM questionnaire scores for participants in the control group.
Study: NCT04467437

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Gait Training
Description: Training that targets rehabilitation of walking function

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Gait Training
Description: Training that targets rehabilitation of walking function

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous Spinal Stimulation
Description: Non-invasive electrical stimulation of the spinal cord over the skin combined with gait training
Study: NCT06059664

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Finerenone Oral Tablet
Description: Blinded study of finerenone vs. placebo in kidney transplant recipients. Participants will take finerenone or placebo once daily for 12 months. The drug will be up- or down-titrated according to potassium levels.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Blinded study of finerenone vs. placebo in kidney transplant recipients. Participants will take finerenone or placebo once daily for 12 months. The drug will be up- or down-titrated according to potassium levels.
Study: NCT05027230

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0601 for Injection
Description: A multiple-dose design to evaluate the safety,tolerability and efficacy of two doses of STSP-0601 for injection in patients with inhibitory hemophilia

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0601 for Injection
Description: A multiple-dose design to evaluate the safety,tolerability and efficacy of two doses of STSP-0601 for injection in patients with inhibitory hemophilia
Study: NCT05745909

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic or open low-anterior resection of the rectum with TME and created loop transverse colostomy
Description: The loop transverse colostomy is matured without torsion using a plastic retainer. The stoma protrudes 2-3 cm. The loop of the transverse colon is sutured with interrupted sutures using an absorbable 3/0 polyglactin suture without piercing the intestinal wall. The intestinal lumen is opened through a transverse incision on the antimesenteric border.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic or open low-anterior resection of the rectum with TME and created loop ileostomy
Description: The loop ileostomy is matured 25-30 cm from the ileocecal angle without torsion and without a retainer, so that stoma protrudes 2-3 cm. The loop of the ileum is sutured with interrupted sutures using an absorbable 3/0 polyglactin suture without piercing the intestinal wall. The intestinal lumen is opened through a transverse incision on the antimesenteric border.
Study: NCT05546879

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NP137
Description: NP137 at 9 or 14 mg/kg IV will be administered every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab will be administered by IV infusion at a fixed dose of 1200 mg on Day 1 of each 21-days cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab will be administered by IV infusion at a dose of 15 mg/kg on Day 1 of each 21-day cycle
Study: NCT06197997

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chicago Parent Program (CPP)
Description: The Chicago Parent Program (CPP) is a 12-session group-based parenting intervention designed to strengthen parenting skills and parent engagement in children's learning and improve children's social-emotional and behavioral competence.
Study: NCT05536635

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: breathing techniques
Description: Intervention will be daily use of breathing techniques thought by the researcher as explained in detail in arm/group descriptions
Study: NCT04896151

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental
Description: The MMPI-2-RF-EX is a broadband, self-report measure of personality and psychopathology was developed for research purposes in order to develop the MMPI-3 (Ben-Porath \& Tellegen, 2020), which is comprised of a subset of MMPI-2-RF-EX items.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental
Description: The MMPI-2-RF-EX is a broadband, self-report measure of personality and psychopathology was developed for research purposes in order to develop the MMPI-3 (Ben-Porath \& Tellegen, 2020), which is comprised of a subset of MMPI-2-RF-EX items.
Study: NCT06006559

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EYU688
Description: EYU688 administered by oral route

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo administered orally as capsules
Study: NCT06112990

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: creatine monohydrate
Description: Creatine is part of the phosphagen system and plays a critical role in energy metabolism. Creatine monohydrate supplementation increases availability of creatine and phosphocreatine in the skeletal muscle. Increased phosphocreatine enables greater buffering of adenosine triphosphate, an organic compound providing energy to cells, enhancing training volume (e.g., an individual can work-out harder and longer).This augmentation in exercise capacity amplifies training adaptations. Additionally, creatine monohydrate supplementation reduces levels of inflammatory markers, which are associated with severe muscle loss.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo supplementation consists of a flavorless, colorless, dextrose powder and will be supplied in concealed, unlabeled packaging.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based, telehealth
Description: Home-based, individualized, whole-body RT program, supervised via the telehealth platform within the electronic medical record system. The RT program consists of 12 resistance exercises, focusing on all major muscle groups including upper and lower body, core, and whole-body. Exercises within each participant's individualized RT program progress with a periodization model as recommended by the American College of Sports Medicine. In addition, the cancer exercise trainer will inquire about space availability in the home for completing resistance prior to developing the personalized prescription. This logistical information is key to ensure feasibility of completing the exercises prescribed. Participants will be provided with beginner and advanced sets of elastic resistance bands to enable progression throughout the 52-week study.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Home-based, telehealth
Description: Home-based, individualized, whole-body RT program, supervised via the telehealth platform within the electronic medical record system. The RT program consists of 12 resistance exercises, focusing on all major muscle groups including upper and lower body, core, and whole-body. Exercises within each participant's individualized RT program progress with a periodization model as recommended by the American College of Sports Medicine. In addition, the cancer exercise trainer will inquire about space availability in the home for completing resistance prior to developing the personalized prescription. This logistical information is key to ensure feasibility of completing the exercises prescribed. Participants will be provided with beginner and advanced sets of elastic resistance bands to enable progression throughout the 52-week study.
Study: NCT05202639

Intervention type: OTHER
Intervention: Questionnaire
Description: A questionnaire will be sent by e-mail to the mother and to the father separately. A return of the completed questionnaire is expected within 6 weeks via a secure internal platform pertained to the HCL (Hospices Civils de Lyon).~The aim of this questionnaire is to identify the factors associated with the continuation or not of pregnancy after diagnosis of severe fetal pathology and after legal authorization of medical termination of pregnancy given by the Multidisciplinary Center of Prenatal Diagnosis.

Intervention type: OTHER
Intervention: Questionnaire
Description: A questionnaire will be sent by e-mail to the mother and to the father separately. A return of the completed questionnaire is expected within 6 weeks via a secure internal platform pertained to the HCL (Hospices Civils de Lyon).~The aim of this questionnaire is to identify the factors associated with the continuation or not of pregnancy after diagnosis of severe fetal pathology and after legal authorization of medical termination of pregnancy given by the Multidisciplinary Center of Prenatal Diagnosis.
Study: NCT05743400

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thymoglobulin 25 milligrams (mg) Injection
Description: Patients will receive thymoglobulin between 5 and 20 milligrams/kilograms (mg/kg) as an intravenous infusion over a period of 2 to 5 days depending on the dose and the transplant package chosen by the physician.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood test
Description: Thymoglobulin® serum levels~Time frame : samples will be drawn at the following points :~* 1 after each end of perfusion ;~* 1 though concentration before each perfusion ;~* 3 blood samples in 3 different days during the first week;~* 1 weekly for 2 weeks post HSCT.
Study: NCT06603168

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Autonomic Recalibration Treatment
Description: An initial history to r/o pathology and document a chief complaint relevant to pain is conducted. An initial head to toe assessment of withdrawal or startle reflex behavior in response to palpation is performed to identify trigger points and establish patterns of sympathetic dominance throughout the myofascial system. The pattern of sympathetic dominance (pattern of trigger point) is addressed during treatment by Primal Reflex Release Technique Protocol to inhibit somatic afferent feedback loops and rebalance the autonomic nervous system towards a state of parasympathetic dominance. The absence of a trigger point indicates that the treatment is complete.
Study: NCT06588569

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multi-mode tumor treatment system
Description: The intervention for this arm involves the use of a novel multi-mode tumor treatment system, developed by Shanghai MAaGI Medical Technology Co., Ltd. The system combines cryoablation and radiofrequency ablation in a single device. During the treatment, the tumor tissue is rapidly frozen to create an ice ball larger than the lesion by 5mm, followed by thawing and rewarming. Subsequently, the lesion is treated with radiofrequency ablation according to conventional procedures to ensure complete ablation within a safety margin of 5-10mm around the tumor.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency ablation therapeutic apparatus
Description: The intervention for this arm involves the use of conventional radiofrequency ablation equipment, which is developed by MedSphere International (Shanghai) Co., Ltd.. During the treatment, the tumor is ablated using predefined power and time settings to ensure complete ablation within a safety margin of 5-10mm around the tumor.
Study: NCT06598618

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Graston technique+ Conventional PT
Description: IASTM technique (graston technique) on iliotibial band. Frequency 2 sessions of stroking with 20 seconds rest in between 3 times/week for 3 consecutive weeks Intensity as tolerated by patient. Conventional PT including 1- Therapeutic ultrasound at frequency of 3.5 MHZ for 10 minutes. 2- Stretching exercise of hamstrings. 3-Isometric exercises of Quadriceps

Intervention type: OTHER
Group type: OTHER
Intervention: Muscle energy technique + Conventional PT
Description: Muscle energy technique (post facilitation stretch) on iliotibial band. Frequency 10 repetitions 3 times/week for 3 consecutive weeks Intensity starting from 50 percent resistance across barrier provided by physiotherapist.. Conventional PT including 1- Therapeutic ultrasound at frequency of 3.5 MHZ for 10 minutes. 2- Stretching exercise of hamstrings. 3-Isometric exercises of Quadriceps.
Study: NCT06598579

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Cognitive Therapy
Description: Mindfulness-Based Cognitive Therapy (MBCT) is a form of psychotherapy that combines principles of cognitive therapy with mindfulness practices focused on increasing non-judgemental awareness of the present moment. It was designed to help individuals, particularly those with depression, stop rumination and a cycle of negative thought patterns that lead to emotional distress including depression. It is a well established depression EBT. The Vietnamese version of the program (MBCT-VN) is a group treatment involving from five to ten participants (depending on how many participants are able to be recruited) per group.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Treatment-as-usual involving Buddhist meditation
Description: MBCT and other mindfulness interventions were originally derived from Buddhist meditation, modifed to be non-secular and focused on treatment of depression and other mental health and behavioral problems rather than on spiritual development. In the present study, a treatment-as-usual condition involving Buddhist meditation will be used. The project will assess the characteristics of the Buddhist meditation delivered for the control group participants at pagoda meditation retreats but will not influence this control condition in any way.
Study: NCT06594484

Intervention type: OTHER
Intervention: Ml Based Algorithm 1
Description: The values in the ML algorithm were selected according to logistic regression analysis and the values used in the other six scores tested. The success rate of the constructed networks correct predictions was considered as the success rate of the algorithm. The usefulness of the test was determined through AUROC analysis. Two algorithms were tested in our study. In the first algorithm (ML1), the dependent variable was erythrocyte suspension (ES) consumption, and the independent variables included patients; demographic data, laboratory data, and operational data

Intervention type: OTHER
Intervention: Ml Based Algroithm 2
Description: is an Ml algorithm created by combining commonly used bleeding scores

Intervention type: OTHER
Intervention: Bleeding Scores
Description: ACTION CRUSCADE TRACK WILL-BLEED PAPWORTH TRUST ACTAPORT skores used to predict ES need
Study: NCT06595927

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Cervical extensor endurance test
Description: Monitoring the clinical parameters of head and neck immobility during the cervical extensor endurance test to correlate them with muscular activity by MRI and other cervical clinical tests

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cervical extensor endurance test
Description: Monitoring the clinical parameters of head and neck immobility during the cervical extensor endurance test to correlate them with muscular activity by MRI and other cervical clinical tests
Study: NCT06592274

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HB0017
Description: 300mg Q12W

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HB0017
Description: HB0017 300mg Q8W

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HB0017
Description: HB0017 150mg Q4W