TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04901312

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adolescent Community Reinforcement Approach
Description: The Adolescent Community Reinforcement Approach (A-CRA) is a developmentally-appropriate behavioral treatment for youth and young adults ages 12 to 24 years old with substance use disorders. A-CRA seeks to increase the family, social, and educational/vocational reinforces to support recovery. This intervention has been implemented in outpatient, intensive outpatient, and residential treatment settings. A-CRA includes guidelines for three types of sessions: individuals alone, parents/caregivers alone, and individuals and parents/caregivers together. According to the individual's needs and self-assessment of happiness in multiple life areas, clinicians choose from a variety of A-CRA procedures that address, for example, problem-solving skills to cope with day-to-day stressors, communication skills, and active participation in positive social and recreational activities with the goal of improving life satisfaction and eliminating alcohol and substance use problems.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adolescent Community Reinforcement Approach
Description: The Adolescent Community Reinforcement Approach (A-CRA) is a developmentally-appropriate behavioral treatment for youth and young adults ages 12 to 24 years old with substance use disorders. A-CRA seeks to increase the family, social, and educational/vocational reinforces to support recovery. This intervention has been implemented in outpatient, intensive outpatient, and residential treatment settings. A-CRA includes guidelines for three types of sessions: individuals alone, parents/caregivers alone, and individuals and parents/caregivers together. According to the individual's needs and self-assessment of happiness in multiple life areas, clinicians choose from a variety of A-CRA procedures that address, for example, problem-solving skills to cope with day-to-day stressors, communication skills, and active participation in positive social and recreational activities with the goal of improving life satisfaction and eliminating alcohol and substance use problems.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Assertive Continuing Care
Description: Assertive Continuing Care (ACC) uses Community Reinforcement Approach (CRA) procedures, home visits, and case management for individuals following an initial substance use treatment episode. It stresses rapid initiation of services after discharge from residential, intensive outpatient, or regular outpatient treatment in order to promote recovery and prevent relapse.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Assertive Continuing Care
Description: Assertive Continuing Care (ACC) uses Community Reinforcement Approach (CRA) procedures, home visits, and case management for individuals following an initial substance use treatment episode. It stresses rapid initiation of services after discharge from residential, intensive outpatient, or regular outpatient treatment in order to promote recovery and prevent relapse.
Study: NCT05975242

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone diabetes management application
Description: The intervention is a smartphone diabetes management application that is combined with structured blood glucose testing.
Study: NCT04843488

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Guided bone regeneration with a PTFE membrane
Description: Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Guided bone regeneration with a PTFE+collagen membrane
Description: Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws and covered with a Collagen membrane subsequently.
Study: NCT06032884

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: continuous renal replacement therapy (CRRT)
Description: renal replacement therapy (RRT).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intermittent hemodialysis (IHD)
Description: renal replacement therapy (RRT).
Study: NCT06477627

Intervention type: OTHER
Group type: OTHER
Intervention: change of environment
Description: The participants will change from inland to coastal environment to see the effect. We will take VAMS blood samples and nose swabs from the participant to measure this effect.

Intervention type: OTHER
Group type: OTHER
Intervention: no intervention
Description: reference groups, stay in their coastal or inland environment

Intervention type: OTHER
Group type: OTHER
Intervention: no intervention
Description: reference groups, stay in their coastal or inland environment
Study: NCT05425160

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive lower limb activities (Chair rise and Step ups)
Description: Progressive lower limb activities (Chair rise and Step ups) were be carried out weekly for upto 6 weeks. Before initiation, cardiopulmonary parameters i.e. Heart rate, oxygen saturation, cardiac output and stroke volume were measured at baseline and later at the termination of activity on each week. Initially, five repeated chair rise were conducted through SPPB and the time was noted to complete the task and step ups through 6MWD for a total period of 30 min. Lastly, fatigue component was assessed via FAS.
Study: NCT04901312

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trauma Affect Regulation Guide for Education and Therapy
Description: Trauma Affect Regulation: Guide for Education and Therapy is a psychosocial intervention for traumatized adolescents, adults, and families, and for workforce and organizational responses to secondary/vicarious traumatization. T4, the 4-session version, provides education about the impact of complex traumatic stress on the brain's stress response system, and strengths-based practical skills for re-setting the trauma-related alarm/survival reactions that occur in complex PTSD.
Study: NCT05425160

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard aerobic exercise i.e. low intensity walking
Description: Standard aerobic exercise i.e. low intensity walking were conducted in both the groups. Follow up phone calls and 1 OPD visit were scheduled accordingly
Study: NCT04901312

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Motivational interviewing is a collaborative, person-centered form of guiding to elicit and strengthen motivation for change.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Motivational interviewing is a collaborative, person-centered form of guiding to elicit and strengthen motivation for change.
Study: NCT05883553

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Usability and added value of device within sexual activity
Description: Participants and there partners will be asked to use the device over the course of 4 months, during which both will provide answers to questionnaires on quality of relation and sexual life, and detailed questions on the usability and the added value of the used device during sexual activity along with overall satisfaction with the device.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Usability and added value of device within sexual activity
Description: Participants and there partners will be asked to use the device over the course of 4 months, during which both will provide answers to questionnaires on quality of relation and sexual life, and detailed questions on the usability and the added value of the used device during sexual activity along with overall satisfaction with the device.
Study: NCT04550221

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Shauriana
Description: The components of this intervention are: four weekly in-person sessions with a trained peer intervention specialist; optional additional in-person or by phone check-ins after the in-person sessions are delivered; and optional monthly group sessions. The four in-person health education and coaching sessions will be delivered once per week, by trained peer facilitators who identify as GBMSM. These sessions will focus on the following topics: sexual health basics (understanding how HIV and STIs are transmitted, prevented, and diagnosed/treated), relationships (types of relationships we have, characteristics of healthy relationships, communication skills), stress and coping (understanding mental health challenges, adaptive and maladaptive coping strategies), and healthy sexuality and empowerment (understanding sexual orientation and gender identity, challenging stereotypes about GBMSM, making sexual choices).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Shauriana
Description: The components of this intervention are: four weekly in-person sessions with a trained peer intervention specialist; optional additional in-person or by phone check-ins after the in-person sessions are delivered; and optional monthly group sessions. The four in-person health education and coaching sessions will be delivered once per week, by trained peer facilitators who identify as GBMSM. These sessions will focus on the following topics: sexual health basics (understanding how HIV and STIs are transmitted, prevented, and diagnosed/treated), relationships (types of relationships we have, characteristics of healthy relationships, communication skills), stress and coping (understanding mental health challenges, adaptive and maladaptive coping strategies), and healthy sexuality and empowerment (understanding sexual orientation and gender identity, challenging stereotypes about GBMSM, making sexual choices).
Study: NCT06006312

Intervention type: DIAGNOSTIC_TEST
Intervention: fecal elastase-1 test
Description: Personal information of the enrolled subjects will be collected and a fecal collection device will be distributed. Fecal elastase-1 levels will be measured after the fecal sample is collected.
Study: NCT04901312

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Opioid Education Workbook
Description: A digital workbook designed to be completed on a computer in about 2 hours. Topics include opioid use, opioid use disorder, and prevention and treatment of opioid overdose.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Opioid Education Workbook
Description: A digital workbook designed to be completed on a computer in about 2 hours. Topics include opioid use, opioid use disorder, and prevention and treatment of opioid overdose.
Study: NCT06006312

Intervention type: DIAGNOSTIC_TEST
Intervention: fecal elastase-1 test
Description: Personal information of the enrolled subjects will be collected and a fecal collection device will be distributed. Fecal elastase-1 levels will be measured after the fecal sample is collected.

Intervention type: DIAGNOSTIC_TEST
Intervention: fecal elastase-1 test
Description: Personal information of the enrolled subjects will be collected and a fecal collection device will be distributed. Fecal elastase-1 levels will be measured after the fecal sample is collected.
Study: NCT06583460

Intervention type: OTHER
Group type: OTHER
Intervention: Early and systematic oncosexological supporting care
Description: Each patient included in the study will be cared by an anthropologist and a sexologist.~This therapeutic support care will be based on :~* 2 qualitative semi-directive interviews (Baseline and M18),~* 2 individual consultations with questionnaires (Baseline and M18).~The qualitative semi-structured interviews will be conducted with the anthropologist, and the individual consultations with the sexologist.~At the end of the first oncosexology consultation, patients will be given the opportunity to decide whether or not to accept further systematic oncosexology support care, which will be based on :~* 3 individual and/or couple consultations,~* 3 group workshops.~Patients are under no obligation to accept this additional oncosexology support care.
Study: NCT06006312

Intervention type: DIAGNOSTIC_TEST
Intervention: fecal elastase-1 test
Description: Personal information of the enrolled subjects will be collected and a fecal collection device will be distributed. Fecal elastase-1 levels will be measured after the fecal sample is collected.

Intervention type: DIAGNOSTIC_TEST
Intervention: 72-hour fecal fat quantification
Description: Enrolled subjects will eat a standard meal (100g of fat) daily for five consecutive days and collect stool samples for the last 72h. The fat content in the sample will be quantitatively detected and the fat absorption coefficient will be calculated.

Intervention type: DIAGNOSTIC_TEST
Intervention: blood sample test
Description: The enrolled subjects will undergo oral glucose tolerance test and will be collected blood samples for measurement of plasma glucose, insulin level, C-peptide level, glycosylated hemoglobin and vitamin.

Intervention type: DIAGNOSTIC_TEST
Intervention: blood sample test
Description: The enrolled subjects will undergo oral glucose tolerance test and will be collected blood samples for measurement of plasma glucose, insulin level, C-peptide level, glycosylated hemoglobin and vitamin.
Study: NCT06392451

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: LIAISON NES FLU A/B, RSV, & COVID-19
Description: The LIAISON® NES FLU A/B, RSV \& COVID-19 real-time (RT) PCR assay is a Point of Care (POC) system that enables the extraction, amplification, detection and differentiation of influenza A, Influenza B, respiratory syncytial virus (RSV) and SARS-CoV-2 viral RNA from dry nasal swabs (NS). The system consists of the LIAISON® NES FLU A/B, RSV \& COVID-19 cartridge, the LIAISON® NES system (with LIAISON® NES Software), and associated accessories. In the LIAISON® NES FLU A/B, RSV \& COVID-19 cartridge, extraction reagents and lyophilized fluorescent probes are used together with corresponding forward and reverse primers to extract and amplify influenza A, influenza B, RSV, SARS-CoV-2 and internal control RNA targets.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: LIAISON PLEX Respiratory Flex Assay
Description: The LIAISON PLEX® (also known as VERIGENE® II) RSP Flex Assay is an automated test for the detection and identification of common viruses and bacteria, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA, from upper respiratory specimens. The VERIGENE® II Respiratory Flex (RSP Flex) Assay is performed on the VERIGENE® II System. The VERIGENE® II System is an automated platform that performs sample preparation and is capable of polymerase chain reaction (PCR) for the detection of target-specific nucleic acids. The VERIGENE® II System is a fully automated, bench-top sample-to-answer device. The test reagents are supplied in a single, disposable test cartridge.
Study: NCT05764278

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercise
Description: exercise group: first bed exercise after 0\~24hr onset ; sit at bed after 24\~48hr onset control group: first bed exercise after 24\~48hr onset ; sit at bed after 48\~72hr onset

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: exercise group: first bed exercise after 0\~24hr onset ; sit at bed after 24\~48hr onset control group: first bed exercise after 24\~48hr onset ; sit at bed after 48\~72hr onset
Study: NCT04813536

Intervention type: OTHER
Intervention: the Standard Shiftwork Index questionnaire
Description: 1. Biographical information: This includes personal data (e.g., age, sex, marital status, and domestic situations), shift details (e.g., shift start and end times), organization of shiftwork, and general job satisfaction~2. Sleep and fatigue: Measures the effect of shiftwork on perceived sleep quality and quantity and fatigue

Intervention type: OTHER
Intervention: the Standard Shiftwork Index questionnaire
Description: 1. Biographical information: This includes personal data (e.g., age, sex, marital status, and domestic situations), shift details (e.g., shift start and end times), organization of shiftwork, and general job satisfaction~2. Sleep and fatigue: Measures the effect of shiftwork on perceived sleep quality and quantity and fatigue
Study: NCT05213260

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Flipped Teaching method
Description: Before the clinical skill laboratory session, the students will receive the learning materials that they have to read and assimilate before the in-class part which will include interactive, discussion-oriented, and practice-oriented activities.
Study: NCT00846326

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: oxymetazoline-fluticasone propionate
Description: Oxymetazoline 0.05% w/v Fluticasone propionate 0.05% w/w 2 squirts in each nostril twice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxymetazoline
Description: oxymetazoline 0.05% w/v and placebo nasal spray 2 squirts in each nostril twice daily
Study: NCT06071819

Intervention type: DIAGNOSTIC_TEST
Intervention: Structured Clinical Interview for DSM-5
Description: A structured interview will be administered to confirm the diagnosis reported in clinical charts

Intervention type: DIAGNOSTIC_TEST
Intervention: Structured Clinical Interview for DSM-5
Description: A structured interview will be administered to confirm the diagnosis reported in clinical charts
Study: NCT05179694

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Prostate biopsy
Description: Prostate biopsy via either the Transrectal route (comparator) or Transperineal route (experimental), each under local anaesthetic.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Prostate biopsy
Description: Prostate biopsy via either the Transrectal route (comparator) or Transperineal route (experimental), each under local anaesthetic.
Study: NCT06415617

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychoeducation
Description: The content of psychoeducation is based on Five Ways of Well-being which covers Be active, Connect, Take Notice, Keep learning and Giving . The participants will be engaged in psychoeducation through group discussion, individualised goal setting and reflective exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Attention control
Description: The content of the sessions mainly focuses on physical health information, such as healthy eating, physical exercise, prevention of falls, and pain management.
Study: NCT04813536

Intervention type: OTHER
Intervention: complete blood picture
Description: 5ml blood to estimate changes of total leucocytic count, Hemoglobin, eosinophilic, monocyte

Intervention type: OTHER
Intervention: complete blood picture
Description: 5ml blood to estimate changes of total leucocytic count, Hemoglobin, eosinophilic, monocyte

Intervention type: OTHER
Intervention: lipid profile
Description: 5ml blood to estimate changes of plasma triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and HDL-C

Intervention type: OTHER
Intervention: lipid profile
Description: 5ml blood to estimate changes of plasma triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and HDL-C
Study: NCT05051449

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Hydrochloride
Description: Ketamine will be administered by a nurse in a 2-week treatment phase, during which participants will receive six IV infusions of 0.5 mg/kg (over 40-50 minutes) ketamine three times per week. Infusion days for patients will be on Mondays, Wednesdays, and Fridays, +/- 1 day. Ketamine infusions will take place at the UMB General Clinical Research Center (GCRC). The GCRC nurse will deliver ketamine within a private exam room. The infusions will last 40-50 min, and the participant will be observed by the GCRC clinical staff for 2 hours post-infusion. Vital signs will be monitored throughout the treatment; specifically, blood pressure, pulse ox and heart rate will be checked prior to treatment, q20 minutes during infusion, and q30-60 minutes after infusion for up to three hours.
Study: NCT05415449

Intervention type: DEVICE
Intervention: Gus gear protective wearable device
Description: Gus gear protective wearable device for central line.
Study: NCT04658030

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VR 360 video surgery preparation
Description: Preparing children on the surgery by a virtual reality 360 degrees video tour from the pediatric ward to the surgery room. In this video all information is given necessary for the surgery. This takes a maximum of 30 minutes and will be performed 1 time.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care as usual
Description: Preparing the children for surgery with the care as usual. A booklet that can be viewed by the children and parents at home.
Study: NCT05709899

Intervention type: OTHER
Group type: OTHER
Intervention: nerve blocks
Description: Comparison of ultrasound-guided erector spinae plane block and transmuscular quadratus lumborum block for postoperative analgesia in abdominal cancer surgeries.

Intervention type: OTHER
Group type: OTHER
Intervention: nerve blocks
Description: Comparison of ultrasound-guided erector spinae plane block and transmuscular quadratus lumborum block for postoperative analgesia in abdominal cancer surgeries.
Study: NCT04400539

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intrapleural photodynamic therapy with videothoracoscopy
Description: MPM patients will be first administrated 20 mg/kg of oral photosensitizer, 5-Aminolevulinic Acid (5-ALA) {Gliolan®}, 4 to 6 hours prior undergoing thoracoscopy (VATS). During VATS procedure, after a qualitative control of the fluorescence of tumor lesions and some guided pleural tumor biopsies, the pleural cavity will be illuminated using a flexible probe and laser source at a specific wavelength for 5-ALA (400-500 nm; 25 J/cm2) during 15 minutes (6 fractions of 2.5 minutes separated by 5 pauses of 2 minutes each to improve tissue oxygenation for the PDT reaction). An IPC device (but no talc) will be inserted and used for pleurodesis and may permit to collect further pleural effusion samples. As 5-ALA has a short half-life and thus does not need extensive precautions to avoid patient photosensitivity, the patient would not stay longer than a standard procedure (about 2-3 days in the hospital)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab Injection
Description: Seven to 10 days after VATS, patients will start to be treated by Nivolumab 240mg IV every 2 weeks till progression (CT-scan reassessment every 8 cycles), unacceptable toxicity, or maximum 2 years.
Study: NCT04712851

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV