TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06266702

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Oil with Phospholipids
Description: Consumed on white bread

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Oil with Phospholipids
Description: Consumed on white bread

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Polyunsaturated Oil Blend
Description: Consumed on white bread

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Polyunsaturated Oil Blend
Description: Consumed on white bread
Study: NCT05286359

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: NxTekTM Malaria Pf Plus Rapid Diagnostic Test Device
Description: NxTekTM Malaria Pf/Pv Plus: A sensitive rapid chromatographic immunoassay for the qualitative detection of histidine-rich protein 2 (HRP2) and Plasmodium lactate dehydrogenase (pLDH) of Plasmodium falciparum(P.f.) on one test line and of pLDH of Plasmodium vivax (P.v.) malaria on a second test line in human whole blood. This test is a lateral flow test for in vitro professional diagnostic use and intended as an aid to early diagnosis of Malaria infection in-patients with clinical symptoms.~NxTekTM Malaria Pf Plus: A sensitive rapid chromatographic immunoassay for the qualitative detection of histidine-rich protein 2 (HRP2) and pLDH on a single test line of Plasmodium falciparum(P.f.) malaria in human whole blood. This test is a lateral flow test for in vitro professional diagnostic use and intended as an aid to early diagnosis of Malaria infection in-patients with clinical symptoms.
Study: NCT04935840

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: FertyBiotic Pregnancy
Description: DHA, folic acid, Iodine, iron, Lactobacillus rhamnosus, Lactobacillus reuterii, magnesium, zinc, vitamin D3, Vitamin C, Vitamin E, Group B vitamins and Biotin

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: 400 mcg of folic acid
Study: NCT05167175

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib tablet
Description: Lynparza (Olaparib tablets) 300 mg should be taken orally twice daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abiraterone acetate
Description: Qingkeshu (Abiraterone acetate tablets) 1000 mg should be taken orally once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone tablet
Description: Prednisone Tablets should be taken 5 mg once daily.
Study: NCT05267990

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Multi-Detector Computed Tomography
Description: Coronary angiography calcium score via Multi-Detector Computed Tomography
Study: NCT05556564

Intervention type: DRUG
Intervention: observational study
Description: No intervention, observational study
Study: NCT04872556

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Laser acupuncture device
Description: The experiment group would arrange laser acupuncture on day1 and day3 after Taxanes treatment. In the mean while, blood tests were performed with the C-Reactive protein, erythrocyte sedimentation rate, Interleukin-6 for each participants. Evaluation would be records on day1, day3, and day 8 after Taxanes treatment.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Pseudo-laser acupuncture
Description: The experiment group would arrange Pseudo-laser acupuncture on day1 and day3 after Taxanes treatment. In the mean while, blood tests were performed with the C-Reactive protein, erythrocyte sedimentation rate, Interleukin-6 for each participants. Evaluation would be records on day1, day3, and day 8 after Taxanes treatment.
Study: NCT04898972

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based stress reduction intervention
Description: The 8-group sessions of MBSR will be conducted once a week, lasting two and a half hours, with two additional sessions in the following two months. Between sessions, participants will have to practice at home for 45 minutes a day, 6 days a week. For the practice, patients and caregivers will be provided with audio files containing the meditations proposed in the classroom, readings, and the diary of the practice. During the sessions, the following mindfulness-based techniques will be introduced: body scan; sitting meditation; awareness movement exercises; and walking meditation.The sessions will be held face to face or online using common videoconferencing platforms, such as Skype or Zoom, based on the preferences of the participants. This will facilitate the participation of patients and caregivers, overcoming the obstacles related to travel. The course will be taught by certified mindfulness teachers with experience in MBSR interventions on patients with respiratory diseases.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Information on stress reduction
Description: COPD patient-caregiver dyads will be delivered by hand, sent by email or by post an information booklet Coping with your chronic disease, targeting COPD patients, to teach them how to manage stress. This booklet, available in Italian, provides simple information on the meaning of stress and anxiety, and suggests some actions that people can implement at home to reduce stress.
Study: NCT05583500

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental: Single group: excentric exercise protocol
Description: Excentric exercise protocol will be performed for all subjets, consisted of 10 sets of 20 repetitions of squats, jumping from a height of 50 cm
Study: NCT05307796

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategy training
Description: The strategy training of focus in this study is metacognitive strategy training intended to build awareness of naming and methods to overcome instances of difficult naming. Strategy training involves (a) teaching the participant to identify instances in which they are unable to name objects, (b) learn a 6-feature framework (e.g. group, use, action) that has been identified to support semantic feature activation in aphasia, (c) learn and practice strategies to utilize the framework in instances of word finding difficulty
Study: NCT04750733

Intervention type: OTHER
Intervention: Assessment
Description: Assessment of core strength and endurance, muscle strength, postural sway in different condition, physical capacity and fatigue
Study: NCT05345288

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BrainHQ cognitive training
Description: Posit Science's BrainHQ exercises are based on the science of neuroplasticity, also called brain plasticity. Brain plasticity is your brain's natural ability to remodel itself throughout life. The brain is always changing, sometimes for better, and sometimes for worse. What BrainHQ's exercises do is harness that change and direct it in ways that can enhance your overall performance and improve the quality of your life. BrainHQ exercises are grouped into six categories: Attention, Memory, Brain Speed, Intelligence, People Skills, and Navigation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BrainHQ control games
Description: BrainHQ also offers control games for research studies. The control activities will be games similar to candy crush, connect four, gem swap and battleship.
Study: NCT03853122

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best current practice exercise programme
Description: Therapeutic Physical Exercise programme based on the protocol of Afredson (for Achilles and patellar tendinopathies) and LEAP (for gluteal tendinopathy).~Achilles tendinopathy: ALFREDSON ECCENTRIC PROTOCOL: 3 sets of 15 repetitions of two eccentric exercises~Patellar tendinopathy: ALFREDSON ECCENTRIC PROTOCOL: 3 sets of 15 repetions of one eccentric exercise~Gluteal Tendinopathy: EXERCISE LEAP PROTOCOL: an exercise programme divided into stages with progression in different exercises, volumes and loads

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental exercise programme
Description: Therapeutic Physical Exercise programme structured in five stages oriented to specific neuromuscular adaptations based on the characteristics of the neuromuscular system, once daily, three times/week, sets, repetitions and load based on individually performed tests.
Study: NCT05624723

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB054707
Description: INCB054707 75 mg will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB054707
Description: INCB054707 75 mg will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB054707
Description: INCB054707 75 mg will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB054707
Description: INCB054707 75 mg will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB054707
Description: INCB054707 75 mg will be administered orally
Study: NCT05843890

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Structured and tailored PainGuide
Description: Participants will receive specific instruction to complete one module a week over the first 4 weeks. Participants will then receive tailored messaging using scores from the assessments completed during T1(baseline visit) from the PROMIS 29+2.~Participants will be asked to complete surveys over 24 weeks.~All participants will also be registered with a Fitbit device that is linked to the PainGuide to capture movement data (daily step counts).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard PainGuide
Description: Participants in the control group will not receive any messaging once enrolled. Participants will be asked to complete surveys over 24 weeks.~All participants will also be registered with a Fitbit device that is linked to the PainGuide to capture movement data (daily step counts).
Study: NCT05943418

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wysa for Worry
Description: The Wysa for Worry cCBT program is a week-based cCBT programme consisting of specialised cognitive behavior therapy (CBT) interventions delivered through a conversational agent.~Each week of the programme focuses on a different CBT technique or intervention, which is explained in a short weekly video. Following each video, the technique or intervention is discussed and practiced with Wysa's AI chatbot.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: App-based Psychoeducation
Description: The control will include the weekly delivery of active psychoeducational resources.
Study: NCT05501665

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Correlative studies
Study: NCT06441760

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video teleconsultation
Description: Each team will participate in 4 video-recorded simulated transports in fully equipped ambulances. Each team will provide resuscitative care in 4 simulated high-risk pediatric transports. EMS personnel will provide care in the ambulance while PEM physicians will provide medical direction remotely using video to communicate with EMS personnel via tablet devices.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Audio support
Description: Each team will participate in 4 video-recorded simulated transports in fully equipped ambulances. Each team will provide resuscitative care in 4 simulated high-risk pediatric transports. EMS personnel will provide care in the ambulance while EM physicians will provide medical direction remotely using audio to communicate with EMS personnel via tablet devices.
Study: NCT04738136

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-1226
Description: S-1226 has two components delivered by inhalation. It is a mixture of perfluorooctylbromide (PFOB) delivered in vapour form within a medical gas mixture containing CO2. The PFOB component remains the same but the medical gas component contains 4%, 8%, or 12% CO2
Study: NCT06215300

Intervention type: GENETIC
Intervention: coronary artery bypass grafting
Description: coronary artery bypass grafting

Intervention type: GENETIC
Intervention: coronary artery bypass grafting
Description: coronary artery bypass grafting
Study: NCT05542667

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Giomer varnish
Description: * After dryness and isolation are accomplished, Giomer varnish ( PRG coat barrier, by Shofu) will be applied once at the first treatment visit, one drop of PRG Coat Barrier ACTIVE will be added to the container provided in the package containing PRG Coat Barrier BASE the materials will be mixed together with a disposable tip provided by the kit a thin layer is to be applied and left untouched for 3 seconds according to manufacturer instructions and finally varnish is to be light-cured.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Fluoride varnish
Description: After dryness and isolation are accomplished, fluoride varnish (Biflourid 10, by Voco ) single-use type, the foil in the single-use Bifluorid 10 will be pierced using Micro-Tim brush, then a thin layer of the varnish is to be applied using a micro brush for four sessions at a frequency of one session each week, the varnish will be left undisturbed for 10-20 seconds then air-dried according to manufacturer instructions.
Study: NCT05872100

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MINDFULNESS BASED APPLICATION
Description: * The effectiveness of mindfulness practices in the field of health~* Breathing exercise~* Discussing and sharing about exercise~* Introduction of informal and formal mindfulness practices~* Communication exercise with conscious awareness~* Sounds and thoughts meditation~* The concept of compassion~* Biological foundations of compassion~* Self-compassion~* Barriers to compassion~* Coping with compelling emotions~* Coping with the intensity of compassion~* Compassionate mindfulness attitudes~* Admission stages and improving acceptance~* Compassion Meditation~* Courtesy Meditation~* My partner activity~* Body Scan~* Mindfulness Sitting Meditation~* Receiving feedback on the development of mindfulness skills and the content of the training program~* Integration of conscious awareness exercises in daily life for the future
Study: NCT06592755

Intervention type: PROCEDURE
Intervention: single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection
Description: The included patients chose to undergo single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection via the subclavian approach based on patients preference.

Intervention type: PROCEDURE
Intervention: conventional open surgery
Description: These patients chose to undergo total thyroidectomy with central compartment neck dissection via conventional open surgery based on patients preference.
Study: NCT06514703

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CT-Guided Genicular Nerve Ablation
Description: This procedure involves using computed tomography (CT) imaging to guide the precise placement of a needle for the ablation of genicular nerves in the knee. The goal is to disrupt the pain signals caused by osteoarthritis, providing long-term pain relief. The intervention is performed under local anesthesia and is aimed at patients who have not responded adequately to conservative pain management strategies.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fluoroscopic-Guided Genicular Nerve Ablation
Description: This procedure utilizes fluoroscopy to accurately guide the needle placement for the ablation of genicular nerves associated with osteoarthritis knee pain. The technique focuses on minimizing pain and improving functional mobility by disrupting nerve pathways that transmit pain signals. Like the CT-guided approach, it is intended for use in patients whose symptoms have not been sufficiently managed with non-invasive treatments.
Study: NCT06618781

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sedation
Description: Preoperatively, 2 mg intravenous midazolam was administered to the patients. Intravenous 0.5 mg/kg propofol and 0.5 mcg/kg fentanyl were used for induction. Intravenous 0.5-1 mg/kg propofol was administered to provide an intraoperative bispectral index of 40-60, and when the Vizel analog score was \>4, intravenous 0.1-1 mcg/kg remifentanil was administered.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sedation + Quadratus Lumborum Block
Description: Before the procedure, the patient was placed in the left lateral position and a Quadratus Lumborum Block was applied at the thoracic 8-10 level. A total of 20 cc blocking fluid consisting of 14 cc of 0.5% bupivacaine and 6 cc of 2% lidocaine was used for the block. A minimum of 30 minutes was waited after the block. 2 mg of intravenous midazolam was administered before being taken to the operating room. Intravenous 0.5 mg/kg propofol and 0.5 mcg/kg fentanyl were used for induction. Intravenous 0.5-1 mg/kg propofol was administered to provide an intraoperative bispectral index of 40-60, and intravenous 0.1-1 mcg/kg remifentanil was administered when the Vizel analog score was \>4.
Study: NCT06619418

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TENS device
Description: will be using an FDA- cleared TENS device for electrical stimulation (TENS 7000, Compass Health Brands) in combination with commercially-available headphones for acoustic stimulation (AKG 845 BT).Will be shown how to use the device, trained on the multimodal stimulation procedure, and sent home with the device for 12 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Integrative health modalities
Description: will be instructed on the integrative health modalities for this study. They will be given a tablet that includes the videos for the visually guided deep breathing. They will also receive the reflective journal and be set up for health coaching visits. At the end of the 12 weeks, this group of participants will return to the U of M campus and complete an interview about satisfaction and usability of the IH modalities.
Study: NCT06621264

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Description: Patients enrolled in this group will receive a detailed 6-month exercise prescription aimed at providing in-home low fatiguing walking training (at light-moderate intensity, or 2-3 out of 10 of the CR10 Borg\&#39;s scale). The program consists of a two daily 10-minute interval walking sessions (1 minute walking : 1 minute resting) at a prescribed speed controlled by a digital metronome (https://www.youtube.com/watch?v=ki8YX_t-0jA). The training speed will be set up according to the patients baseline walking capacity (approximately 50% lower than the habitual gait speed) and will be weekly increased until reaching the habitual gait speed. The training time will be maintained constant throughout the entire program. Exercise prescription will be updated during two intermediate hospital visits at the 1st and 3rd months. Patients will be provided with a digital application properly developed to keep pacing and to record the correct training execution.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control (Standard treatment)
Description: Patients enrolled in the Co group will receive standard CKD-PAD care, including optimal medical therapy and nutritional advices
Study: NCT06621199

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitoxantrone hydrochloride liposome
Description: Mitoxantrone hydrochloride liposome 24 mg/m\^2 on day 1, every 4 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Cytarabine 100 mg/m\^2 on day 1-5, every 4 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax 100 mg on day 2，200 mg on day 3，400 mg on day 4-10, every 4 weeks
Study: NCT06622967

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CadAI-B
Description: The ultrasound is performed following the usual process. If there are any lesions or areas of concern identified by the patient, a more detailed analysis is conducted on the affected area.~When a lesion is confirmed, the examiner verifies the results through the frozen image, while also securing the results displayed on CadAI-B.~The examiner uses the analysis from CadAI-B as a reference to make the final BI-RADS classification.~Static images and cine clips are captured from the most suspicious areas.
Study: NCT06360003

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Right Ventricular Outflow Tract Posterior Septum Pacing
Description: The Right Ventricular Outflow Tract (RVOT) posterior septum pacing is routinely performed to observe the QRS complex characteristics of the 12 lead ECG (with a focus on comparing their differences with the R-wave amplitude of spontaneous ventricular arrhythmias in the right chest (V1\~V3) leads). When the pacing-induced R-wave amplitudes are all lower than spontaneous VAs in V1\~V3, we predict the origin of Left Ventricular Outflow Tract (LVOT), mapping and ablation in LVOT; otherwise we predict the origin of RVOT, mapping and ablation in RVOT.If fails, go to the opposite site to do mapping and ablation. If still fails, go to distal great cardiac vein (DGCV) to do mapping and ablation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: systemic mapping and ablation
Description: The TC or ST ablation catheter is delivered to ventricular outflow tract (VOT) to perform systemic mapping and ablation.
Study: NCT06622252

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 13-week session program
Description: The newly designed intervention was split into three major components - Healthy Literacy, Caregiver Wellness, and Culturally Competent Care and is delivered throughout a 13-session program delivered via Zoom. Sessions are guided by a psychologist, nutritionist, spirituality specialist, social worker, case coordinator, oncologist and traditional Chinese medicine practitioner. Sessions are intended for caregivers specifically, however, other members of the family may join if they choose to.