TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05944809

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rhTPO
Description: Standard treatment options:~Radiotherapy: 95% planning target volume （planning target volume，PTV） ≥45Gy(without simultaneous boost).~Concurrent chemotherapy:~Weekly regimen: paclitaxel 50mg/m2 d1, nedaplatin/cisplatin 25 mg/m2d1, a total of 5 cycles.~Three weeks regimen: paclitaxel 135-175mg/m2 d1, nedaplatin/cisplatin 80mg/m2, a total of 2 cycles.~The active bone marrow was determined by magnetic resonance（magnetic resonance，MR）, and the dose limits are: V5\<95%,V10\<85%,V20\<60%，V30\<40%；95%PTV\>45Gy.~rhTPO，15000U ih. qw(during the radiotherapy course)
Study: NCT06026072

Intervention type: OTHER
Group type: OTHER
Intervention: CLAD-V SCORE
Description: the CLAD-V score is measured by the doctor during the emergency take care. After 7 days the patient will be call back to compare the prediction of CLAD-V score and the reality of surgical intervention or no.
Study: NCT04737083

Intervention type: GENETIC
Intervention: CGH array
Description: a CGH array is systematically offer to women when the fetus show bilateral clubfoot during prenatal ultrasound screening
Study: NCT05085041

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-Component eHealth Intervention, namely Healthy Online Parental Education (HOPE)
Description: The investigators will provide 8 sessions of a multi-component education intervention to the participants in the intervention group. Each session will address parental nutrition knowledge, self-efficacy, and attitudes around feeding, parental modeling of healthy foods, and skill development to increase success in making behavioral changes. The intervention curriculum will be informed by Social Cognitive Theory to help parents guide young children to engage in healthy eating behaviors through modeling (Curriculum Design). The investigators will deliver the intervention using multicomponent to enhance and maximize the learning experiences of the participants for successful behavior changes. The intervention will be comprised of instructional videos, text messages with key information, online cooking activities, and telephone consultation (Modality).
Study: NCT05281627

Intervention type: OTHER
Intervention: Emergency Laparotomy
Description: All patients undergoing Emergency Laparotomy
Study: NCT05296551

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Motor Task
Description: A visuomotor task is presented where an individual must match their knee to an ellipse that moves up and down on a screen, resulting in a marching-in-place motion at a specified frequency.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive-motor dual-task
Description: While performing the Motor Task intervention, letters of different colors and orientation randomly appear one at a time on the screen. During the Cognitive-motor dual-task, individuals are instructed to count the number of times that either 1 (simple cognitive task), or 2 (complex cognitive task) characters appear on the screen during the motor task.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive-motor dual-task
Description: While performing the Motor Task intervention, letters of different colors and orientation randomly appear one at a time on the screen. During the Cognitive-motor dual-task, individuals are instructed to count the number of times that either 1 (simple cognitive task), or 2 (complex cognitive task) characters appear on the screen during the motor task.
Study: NCT06158464

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional Capacity Evaluation
Description: In a FCE, an occupational therapist will evaluate a patient's ability to perform work-related tasks, using a battery of tests. Depending on the circumstances, he/she will for instance test fatigue, ask the patient to kneel, lift objects, or assess concentration. This assessment lasts ± 4 hours and includes physical tests and tests related to the (previous or reference) profession of the client. This means that an explicit match is made between the functional capacities of the patient (what is he/she capable of) and the demands of a certain job (what is he/she expected to do). Following this assessment, the occupational therapist will explain the results of this assessment to the patient. The evaluation will therefore take place during one or two visits.
Study: NCT06093542

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD7053
Description: Randomised participants will receive AZD7503 subcutaneously.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Randomised participants will receive placebo subcutaneously.
Study: NCT05375162

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General Mindfulness Training
Description: Participants assigned to this condition will be instructed to watch 1 (1-2 mins), mindfulness education videos each week which lay the foundation for what mindfulness is and how it can be an important health behavior. Each week participants will also be asked to listen to general guided mindfulness audio files ≥5 days/ week. The length of recordings will gradually increase each week from 3-5 to 25-30 minutes. All videos and recording will be available via the Opt2Move app.
Study: NCT05645796

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Adopted contrast media amount by using different approaches
Description: Using different contrast media approaches recommended by literature to explore the impact on the contrast enhancement in chest CT

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Adopted contrast media amount by using different approaches
Description: Using different contrast media approaches recommended by literature to explore the impact on the contrast enhancement in chest CT
Study: NCT05375162

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General Mindfulness Training
Description: Participants assigned to this condition will be instructed to watch 1 (1-2 mins), mindfulness education videos each week which lay the foundation for what mindfulness is and how it can be an important health behavior. Each week participants will also be asked to listen to general guided mindfulness audio files ≥5 days/ week. The length of recordings will gradually increase each week from 3-5 to 25-30 minutes. All videos and recording will be available via the Opt2Move app.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MVPA-Specific Mindfulness Training
Description: Participants assigned to the MVPA-specific mindfulness training component will be instructed to watch 1-2 brief (1-2 minute), mindfulness education videos each week which lay the foundation for what mindfulness is and the importance of linking mindful awareness with MVPA. Each week participants will be provided access to MVPA-specific guided mindfulness audio files (e.g., 10-minute treadmill walking meditation, 20-minute bicycling meditation) that they will be asked to listen to during ≥3 MVPA sessions/week. The length and intensity of these audio files will correspond to their progression in the program. All videos and recordings will be accessed via the Opt2Move app.
Study: NCT04742010

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zoledronic Acid
Description: * A single treatment 21 days before bariatric surgery with Zoledronic acid 5 mg or placebo (an interval of 5 to 180 days is accepted)~* Pharmaceutical form: Solution for infusion (100 ml normal saline containing 5 mg zoledronic acid or placebo)~* Administration: slow intravenous infusion with a duration of at least 15 minutes

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: as above
Study: NCT06558032

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tamsulosin 0.4 mg Sustained Release Tablet (produced by PT Dexa Medica, Indonesia)
Description: One tablet of the test drug was given orally under fasting condition

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Harnal® OCAS 0.4 mg Prolonged Release Tablet (produced by Astellas Pharma Europe B.V., The Netherlands, imported by PT Combiphar, Indonesia)
Description: One tablet of the test drug was given orally under fasting condition
Study: NCT05375162

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MVPA-Specific Mindfulness Training
Description: Participants assigned to the MVPA-specific mindfulness training component will be instructed to watch 1-2 brief (1-2 minute), mindfulness education videos each week which lay the foundation for what mindfulness is and the importance of linking mindful awareness with MVPA. Each week participants will be provided access to MVPA-specific guided mindfulness audio files (e.g., 10-minute treadmill walking meditation, 20-minute bicycling meditation) that they will be asked to listen to during ≥3 MVPA sessions/week. The length and intensity of these audio files will correspond to their progression in the program. All videos and recordings will be accessed via the Opt2Move app.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MVPA-Specific Mindfulness Training
Description: Participants assigned to the MVPA-specific mindfulness training component will be instructed to watch 1-2 brief (1-2 minute), mindfulness education videos each week which lay the foundation for what mindfulness is and the importance of linking mindful awareness with MVPA. Each week participants will be provided access to MVPA-specific guided mindfulness audio files (e.g., 10-minute treadmill walking meditation, 20-minute bicycling meditation) that they will be asked to listen to during ≥3 MVPA sessions/week. The length and intensity of these audio files will correspond to their progression in the program. All videos and recordings will be accessed via the Opt2Move app.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MVPA-Specific Mindfulness Training
Description: Participants assigned to the MVPA-specific mindfulness training component will be instructed to watch 1-2 brief (1-2 minute), mindfulness education videos each week which lay the foundation for what mindfulness is and the importance of linking mindful awareness with MVPA. Each week participants will be provided access to MVPA-specific guided mindfulness audio files (e.g., 10-minute treadmill walking meditation, 20-minute bicycling meditation) that they will be asked to listen to during ≥3 MVPA sessions/week. The length and intensity of these audio files will correspond to their progression in the program. All videos and recordings will be accessed via the Opt2Move app.
Study: NCT06354400

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core stabilization training
Description: Isometric exercises of the abdominal muscles in the supine, prone, and squatting positions; isotonic exercises in the supine, prone, squatting, and side-lying positions; isotonic exercises in coordination with the extremity movements in the supine, prone, and crawling positions; and trunk rotation exercises in the sitting position will be performed. The Swiss ball will be used for dynamic exercises. It will include isometric and isotonic exercises of the abdominal muscles. Exercises will start with 3 sets of 20 repetitions, gradually increase in intensity on static and dynamic surfaces, and progress towards difficulty. Each exercise will be performed in coordination with breathing control. Breathing control will be coordinated with every exercise.
Study: NCT06479434

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Females diagnosed with polycystic syndrome will be given metformin tablets for 8 weeks and followed up. Blood samples will be collected along with anthropometric data (weight (kg), height (m) etc)
Study: NCT06436209

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multitask Practice Intervention (MPI)
Description: Multitask practice intervention (MPI) includes multiple behavioral testing sessions during which participants receive practice with multitasking two tasks using the psychological refractory period procedure.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Single-task Practice Intervention (SPI)
Description: Single task practice intervention (SPI) includes multiple behavioral testing sessions during which participants receive separate practice on two tasks.
Study: NCT05373082

Intervention type: OTHER
Intervention: questionnaire completion
Description: Questionnaire to be completed by patients
Study: NCT05877352

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intraoperative Electron Radiotherapy (IOERT)
Description: IOERT can be defined as the direct application of high-energy electron beam irradiation to a tumour bed during an operative procedure. This approach permits precise delivery of a single large fraction of radiation directly and specifically to high recurrence risk anatomical target areas, which the treating clinicians (surgeon and attending clinical oncologist) predict will be a close or involved margin, while simultaneously displacing and shielding dose-limiting radiosensitive structures such as the small bowel or ureter or any anastomoses, if not involved by tumour.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intraoperative Electron Radiotherapy (IOERT)
Description: IOERT can be defined as the direct application of high-energy electron beam irradiation to a tumour bed during an operative procedure. This approach permits precise delivery of a single large fraction of radiation directly and specifically to high recurrence risk anatomical target areas, which the treating clinicians (surgeon and attending clinical oncologist) predict will be a close or involved margin, while simultaneously displacing and shielding dose-limiting radiosensitive structures such as the small bowel or ureter or any anastomoses, if not involved by tumour.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extended Margin Surgery
Description: Surgery intended to remove both a tumour and any metastases

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extended Margin Surgery
Description: Surgery intended to remove both a tumour and any metastases

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extended Margin Surgery
Description: Surgery intended to remove both a tumour and any metastases
Study: NCT05775874

Intervention type: DRUG
Group type: OTHER
Intervention: AZD4547
Description: Initiation dose: 80mg BID,po.

Intervention type: DRUG
Group type: OTHER
Intervention: Tislelizumab
Description: Tislelizumab:200mg Q3W
Study: NCT04996160

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Description: Oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Description: Oral
Study: NCT04901988

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab 10 MG/ML
Description: Eligible patients randomised to Arm B will receive 480 mg nivolumab monotherapy 4 weekly via IV infusion for up to 2 years.
Study: NCT06058286

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Continuous quality improvement
Description: Continuous quality improvement (CQI) is an approach to develop healthcare providers' capacity to improve quality of care processes and improve adherence to clinical guidelines. Key features of CQI include systematic, data-guided activities, designing interventions (or changes to facility processes) with local conditions in mind, and iterative development and testing of interventions. The approach is based on the premise that valuable improvement in organisational processes can be achieved through bottom-up initiatives of stakeholders and providers. It requires a 'team-based' culture of staff working together to collect and use available data to evaluate the effect of local solutions. Facility staff drive the development of solutions to quality of care shortcomings that they feel are best suited to the local context, and CQI works within existing resource constraints so it does not require large long-term investments to sustain improvements.
Study: NCT03988283

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Personalized neoantigen DNA vaccine
Description: At each vaccination time point, patients will receive one injection of the neoantigen DNA vaccine, one injection into the vastus lateralis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Papivax Biotech TDS-IM v2.0
Description: All study injections will be given intramuscularly using an integrated electroporation device (TDS-IM v2.0 device - Papivax Biotech).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Peripheral blood draw
Description: -After trial enrollment and up to 7 days after the first vaccine dose (baseline); no more than 2 weeks after the 3rd vaccine dose; no more than 2 weeks after the 6th vaccine dose; two weeks after the last dose; time of progression or discontinuation (optional)
Study: NCT06633237

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core training program in female amateur basketball players
Description: The intervention consists of a core training program specifically designed to improve core and trunk stability in female amateur basketball players. The program is integrated into the warm-up routine and is applied twice a week over an 8-week period. Each session lasts approximately 12-15 minutes and includes five exercises. The training program is divided into three phases of progression, gradually increasing the difficulty of the exercises over the 8 weeks by incorporating more dynamic and functional movements.
Study: NCT06427837

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Same 2nd course
Description: The same snack food will be served in the second course

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Different 2nd course
Description: A different snack food will be served in the second course
Study: NCT06406218

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Phase I Cardiac Rehabilitation Exercise Training
Description: A) In the morning, take a supine position and perform straight leg raises with each leg individually, lifting to a height of 30° and holding for 3-5 seconds. Raise both arms to the side of the head to a 90° angle and hold for 5-10 seconds. Inhale deeply when exerting force and exhale slowly when lowering. Alternate between leg lifts and arm raises, performing 5 sets per session. Adjust intensity based on individual condition and may be repeated. In the afternoon, sit beside the bed for 5 minutes. B) After transitioning to secondary care according to the patient's condition, stand beside the bed for 5 minutes in the morning; in the afternoon, march in place beside the bed for 5 minutes. C) Walk beside the bed for 10 minutes per session, twice a day. D) Move around and doing activities under supervision inside the ward, 10 minutes per session, twice a day.~Spend approximately one day at each level, gradually progressing the exercise to the patient's tolerance level.
Study: NCT05149677

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music therapy
Description: Music therapy intervention + Standard of Care for labor pain
Study: NCT06179927

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: QT voice
Description: The subjects will undergo a pre-intervention assessment phase that will consist of administering the Theory Of Mind (TOM) test found in the NEuroPSYcology second edition (NEPSY) battery, part A; the same test will be re-submitted at the end of the intervention. Having ascertained the presence of the inclusion criteria and following randomization of the sample, the Experimental Group constituted of 20 children, will be administered the research task, which involves 12 sessions, one per week lasting 45 minutes. the experimental group will view 12 social scenes made via tablet. In the scenario, the depictions will be presented in color. They, guided by QT Robot's narrator voice, will have to choose from two or three alternatives the one that represents the appropriate mental state by selecting it on the tablet. Consequently, audio visual feedback will be provided, via the robot, to return information to the subject about the accuracy of the response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Image stimuli
Description: The subjects will undergo a pre-intervention assessment phase that will consist of administering the Theory Of Mind (TOM) test found in the NEuroPSYcology second edition (NEPSY) battery, part A; the same test will be re-submitted at the end of the intervention. Having ascertained the presence of the inclusion criteria and following randomization of the sample, the control group constituted of 20 children, will be administered the research task, which involves 12 sessions, one per week lasting 45 minutes. the experimental group will view 12 social scenes on paper. They, guided by the narrator's voice of the operator will have to choose from two or three alternatives the one that represents the appropriate mental state by indicating it on the paper. Consequently, feedback will be provided by the operator to return information to the subject on the accuracy of the response.
Study: NCT06430359

Intervention type: DIAGNOSTIC_TEST
Intervention: urine and blood test
Description: 3 urine collections of an 8h period. One blood sample for liver function test and copper assessment

Intervention type: DIAGNOSTIC_TEST
Intervention: urine and blood test
Description: 3 urine collections of an 8h period. One blood sample for liver function test and copper assessment

Intervention type: DIAGNOSTIC_TEST
Intervention: urine and blood test
Description: 3 urine collections of an 8h period. One blood sample for liver function test and copper assessment
Study: NCT05990153

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial Release (MR)
Description: Myofascial release therapy is a type of gentle, constant massage that releases tightness and pain throughout myofascial tissues.
Study: NCT06386055

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active exercise
Description: The intervention group will be provided with training courses for 3 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active exercise
Description: The intervention group will be provided with training courses for 3 months.
Study: NCT05228132

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pristine™ Long-Term Hemodialysis Catheter
Description: Placement of the Pristine™ Long-Term Hemodialysis Catheter Placement.
Study: NCT05948527

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high flow nasal canula
Description: administration of high flow nasal canula at initial flow 35 liters per minute and Fio2 (fraction of inspired oxygen of 50%) with titration to reach oxygen saturation of 88-92%.
Study: NCT01297946

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Conventional continuous subcutaneous insulin infusion therapy

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual-hormone closed-loop