TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05735600

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AyuDa Virtual: Aprender y Utilizar Decisiones Apreciables (Spanish) - Learning and Utilizing Significant Choices (English)
Description: The intervention was developed based on the Social Learning Theory, considering both environmental and cognitive factors influencing parent behavior and modeling for children. Researchers have modified a five-module virtual intervention from the Cooking Healthy and Delicious Manual (Cocinando Delicioso y Saludable Manual, Spanish version), which incorporates behavior change strategies for improving diet quality, screen time, physical activity/sedentary behavior, socioeconomic status/food security, and sleep duration.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: AyuDa Written: Aprender y Utilizar Decisiones Apreciables (Spanish) - Learning and Utilizing Significant Choices (English)
Description: The intervention was developed based on the Social Learning Theory, considering both environmental and cognitive factors influencing parent behavior and modeling for children. Researchers have modified a five-module virtual intervention from the Cooking Healthy and Delicious Manual (Cocinando Delicioso y Saludable Manual, Spanish version), which incorporates behavior change strategies for improving diet quality, screen time, physical activity/sedentary behavior, socioeconomic status/food security, and sleep duration.
Study: NCT06031103

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mini-PCNL procedure
Description: Mini-PCNL~. A 12 Fr rigid nephroscope and a Holmium:YAG laser as energy source was used for surgery Percutaneous renal puncture was achieved with an 18 Ga needle after displaying renal collecting system with contrast material. and tract dilatation was achieved using Amplatz dilators up to 16-18 Fr according to patient age

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: RIRS procedure
Description: RIRS Technique the 9.5 Fr ureteral access sheath (UAS). UAS was inserted over the guide wire under fluoroscopy control. A flexible ureteroscope was passed through the UAS. If the UAS did not pass over the guide wire, the investigator moved the flexible ureteroscopy over the guide wire without access sheat
Study: NCT05316116

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Siltuximab
Description: Siltuximab will be given on day 1 of each cycle. The dose will be 11 mg/kg given over 1 hour by intravenous infusion. Each cycle is three weeks (+-3 days).
Study: NCT05734105

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ripretinib
Description: 50 mg tablets

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sunitinib
Description: 12.5 mg tablets
Study: NCT05959759

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dimethyl fumarate
Description: dimethyl fumarate enteric capsule (the initial dose is 120 mg twice a day, and after 7 days, the dose will be increased to the maintenance dose of 240 mg twice a day, for 6 months), 30 patients for this arm.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo with the same appearance (color, taste, size, shape), 30 patients for this arm.
Study: NCT04912687

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: EGFR gene mutation analysis on liquid biopsy
Description: Blood samples will be collected at inclusion for plasma DNA collection and analysis.
Study: NCT04558398

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance exercise training
Description: Each session will be performed at home, with resistance bands used to provide resistance. Participants will be guided to increase the resistance if over 15 repetitions can be performed prior to fatigue. Weekly contact will be made with participants to encourage participation and to guide the exercise.~Each session will include:~2 min warm-up jogging on the spot~2 sets of 12-15 repetitions of:~Squats~Hip flexion~Hip extension~Hip abduction~Seated row~Bench press~Lateral raises~2 min jogging on the spot cooldown.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-intensity interval training
Description: Each session will include:~* 2 min warm-up: jogging on the spot~* Each of the following exercises performed for 60seconds, interspaced by 90 seconds rest~  * Star jumps~ * Standing squats~ * On-the-spot sprints~ * Standing squats~ * Star jumps~* 2 min cool-down: jogging on the spot~Participants will be contacted weekly to encourage participation and to guide the exercise
Study: NCT04907019

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rifampicin，SY-004
Description: On the morning of D1, the subjects will take orally 80 mg of SY-004 Capsules on an empty stomach.Fasting will be performed within 4 hours after taking the medicine. From D8 to D14, the subjects will take orally 600 mg rifampicin before breakfast every day. On the day of D15, the subjects will take orally 600 mg rifampicin and 80 mg SY-004 Capsules on an empty stomach.~From D16 to D21, subjects will take orally 600 mg of rifampicin before breakfast every day.The patient can be discharged from the hospital after completing the safety examination on D22.
Study: NCT04472416

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VRD in addition to standardized analgesic protocol
Description: Use of VRD in addition to standardized analgesic protoco for abdominal VAC dressing change
Study: NCT05185505

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: 1200 mg administered every three weeks for up to 6 months (up to 8 cycles) during the liver transplant waiting period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: 15 mg/kg administered every three weeks for up to 6 months (up to 8 cycles) during the liver transplant waiting period
Study: NCT06633926

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition Education
Description: Given nutrition education

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Counseling
Description: Given lifestyle recommendations

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yoga
Description: Participate in yoga

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Marma therapy
Description: Participate in marma therapeutic touch

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: Attend online HEI sessions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality of Life Questionnaire Administration
Description: Self-reported questionnaires are given to participants to complete

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality of Life Questionnaire Administration
Description: Self-reported questionnaires are given to participants to complete
Study: NCT05695560

Intervention type: OTHER
Intervention: No Intervention
Description: As this is an observational study, no intervention will be administered.

Intervention type: OTHER
Intervention: No Intervention
Description: As this is an observational study, no intervention will be administered.
Study: NCT06114303

Intervention type: OTHER
Intervention: Stool sampling
Description: 1 stool sample is taken during the study with a stool sample kit

Intervention type: OTHER
Intervention: Stool sampling
Description: 1 stool sample is taken during the study with a stool sample kit
Study: NCT06122675

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DBS
Description: Implanted in the cerebellum.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: DBS
Description: Implanted in the cerebellum.
Study: NCT06645366

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Treatment with BTL-785F
Description: Three (3) treatment sessions will be applied to the subjects' face and neck using the BTL-785F system equipped with the BTL-785-4-4 tip on BTL-785-4 applicator, lasting from 20 to 60 minutes depending on the size of the treated area. Each treatment will be spaced 2 - 6 weeks apart, after the complete healing of scabs.
Study: NCT05092126

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Calculate oxygen consumption

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Calculate oxygen consumption
Study: NCT06405100

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Supportive care+Prednisone
Description: Supportive care: Control blood pressure:ACEI/ARB; Diet that is low in fat and salt; Stop smoking; Moderate exercise.~Induction period: 1mg/kg/day. The maximum dose is not more than 60mg. The duration of adequate prednisone is a minimum of 4 weeks and a maximum of 16 weeks.~Maintenance period: A reduction of 5-10mg/wk was initiated after 2 weeks of complete remission and finally discontinued after 6 months of maintenance at 5mg/day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Supportive care+Tacrolimus+Ripertamab
Description: Supportive care: Control blood pressure:ACEI/ARB; Diet that is low in fat and salt; Stop smoking; Moderate exercise.~Tacrolimus：Induction period: 0.05mg/kg/d. It will be given in two doses 12 hours apart. The blood concentration should be up to 5-10ng/ml. Maintenance therapy was initiated two weeks after complete remission; Maintenance period: Reduced to a blood concentration of 3-8ng/ml, and stopped after 6 months of maintenance treatment.~Ripertamab: Given twice every two weeks at a dose of 1000mg. 1000mg is added at 6 months.
Study: NCT05798715

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gleptomet 50/1000(Metformin HCl & Sitagliptin)
Description: Test drug

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Janumet 50/1000(Metformin HCl & Sitagliptin)
Description: Reference drug
Study: NCT06331663

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remifentanil
Description: first start with remifentanil 5.0 ng/ml, and use the up and down method as adjust 0.5 ng/ml of concentration of remifentanil each time. Inadequate antinociception (Surgical Pleth Index(SPI) \> 80 and hyperdynamics (the increased heart rate (HR) and mean blood pressure (MBP) above 20% of baseline or HR\>100bpm and arterial blood pressure(ABP)\>180/100mmHg)) is defined as failure, therefore we increase remifentanil by 0.5 ng/ml; otherwise, the setting is considered successful without abovementioned situations.
Study: NCT06402383

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaccination Provision
Description: HPV vaccination #1 will be offered by provider at the first visit when the HPV self-sample is collected. HPV Vaccination #2 will be offered at 6 months for HPV negative women and at 12 months for HPV positive women.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaccination Provision 2
Description: HPV vaccination #1 will be offered by the provider after an HPV negative result is received with vaccine #2 given at 3 months after negative test results obtained.~For HPV positive women - vaccination #1 will be offered at 12 months and vaccination #2 will be offered at the 15 month mark.
Study: NCT06225843

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sotevtamab
Description: Sotevtamab is an inhibitor of the epithelial to mesenchymal transition. It is a fully humanized monoclonal antibody of IgG2 isotype against tumor-associated secreted clusterin (TA-sCLU)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: FOLFOX
Description: FOLFOX is a chemotherapy regimen for treatment of colorectal cancer, made up of the drugs folinic acid, fluorouracil, and oxaliplatin.
Study: NCT06405100

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Supportive care+Ripertamab
Description: Supportive care: Control blood pressure:ACEI/ARB; Diet that is low in fat and salt; Stop smoking; Moderate exercise.~Ripertamab: Given twice every two weeks at a dose of 1000mg. 1000mg is added at 6 months.
Study: NCT06111768

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: Receipt of 10mg oral dose of dapagliflozin once daily for three days
Study: NCT05049057

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Erenumab 140 Mg/mL Subcutaneous Solution
Description: Active erenumab delivered via subcutaneous injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo delivered via subcutaneous injection.
Study: NCT06195930

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vericiguat (BAY1021189) 5 mg
Description: Vericiguat (BAY1021189) will be taken as 5 mg tablet 1x daily over at least 14 days up to 18 days (+ 4 days time window allowed)
Study: NCT04194840

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical therapy consult
Description: Physical therapy consult to assess physical functioning on a separate office visit prior to attending the Transplant Wellness Clinic. Full evaluation that incorporates several tools to measure the risk of falling and to assess mobility and strength

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive Assessment
Description: Montreal cognitive assessment (MoCA) and the Blessed Orientation-Memory-Concentration Test (BOMC)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cancer Aging Research Group (CARG) assessment
Description: CARG assessment - utilized to capture information about a participant's medical history as well as functional, cognitive, and psychosocial status

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medication Review
Description: Medication Review via Beers Assessment

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutrition assessment
Description: Nutrition assessment Via Mini Nutrition Assessment (MNA)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laboratory studies
Description: Laboratory studies including urine toxicology screen, C-reactive protein, albumin, pre-albumin, vitamin D

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient satisfaction questionnaire
Description: Patient satisfaction questionnaire

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physician Questionnaire
Description: Physician Questionnaire:~Questionnaire to learn about physician satisfaction with information received from reports and participant questionnaires.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient follow-up questionnaire
Description: Patient follow-up questionnaire:~Questionnaire to learn more about participant opinions concerning the clinic and the quality of care received during visits with specialists
Study: NCT06151093

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video-based games intervention
Description: These games are applied via using Nintendo Wii~1st - 2nd Week Applications~* Basic Step~* Penguin slide (right-left weight transfer)~* Snowball flight (right-left weight transfer)~* Tilt city (right-left weight transfer)~  3rd-4th Week Applications~* Advanced Step~* Snowball flight (right-left weight transfer)~* Penguin slide (right-left weight transfer)~* Table tilt (weight transfer in 4 directions)~  5th-6th Week Applications~* Advanced Step~* Table tilt (weight transfer in 4 directions)~* Balance bubble (weight transfer to 4 directions)~* Ski slalom (weight transfer in 4 directions)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Balance exercises
Description: 1st-2nd Week Applications On a flat-hard surface;~* Standing on 2 legs~* Stepping forward and backward (separately for both feet)~* Getting into the tandem position and maintaining the position (separately for both feet)~* Standing on one leg (separately for both feet)~* Weight transfer in four directions~* Taking a step back towards the step~* Stepping on the stability ball~  3rd-4th Week Applications All exercises which applied in 1st and 2nd week are applied on mat.~  5th-6th Week Applications On the balance board;~* Standing on 2 legs~* Stepping forward and backward (separately for both feet)~* Getting into the tandem position and maintaining the position (separately for both feet)~* Standing on one leg (separately for both feet)~* Weight transfer in four directions~* Catching balls thrown by the enforcer
Study: NCT06339853

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WELT-IP with wearable devices (Apple/galaxy watch. Oura ring)
Description: WELT-IP (an investigational digital therapeutic) is an CBT-I based intervention designed to treat insomnia, conducted in 6 sessions. It is a comprehensive program delivering sleep restriction, stimulation control, muscle relaxation, cognitive treatment, and sleep hygiene education. Main features are sleep diary, sleep reports, daily lessons of CBT-I, muscle relaxation techniques, and cognitive intervention through chatbot. By using WELT-IP simultaneously with wearing an Apple Watch/Galaxy Watch and Oura Ring, sleep and environmental data can be collected.
Study: NCT05447065

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D supplement
Description: Only the experimental group (D) received the vitamin D supplement.
Study: NCT06228716

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Training with hybrid simulation method
Description: Subcutaneous biological drug self-administration training was given by the researcher in two stages, theoretical and practical, face to face. Power point presentation and training brochure were used in theoretical training. The practical training given after the theoretical training was given using the Hybrid simulation method. The Wearable Subcutaneous Injection Hybrid Simulator developed by the researcher was worn by the individuals after being informed about its purpose and function. Afterwards, they were expected to apply the subcutaneous application step by step as explained to them. Each application step they made incorrectly was corrected and repeated with the support of the researcher. The application was considered successful if they completed all application steps correctly from start to finish. The training took approximately 40 minutes. After the practical training, the individuals' questions, if any, were answered and the training was terminated.
Study: NCT06215235

Intervention type: OTHER
Intervention: Bright light therapy
Description: for 2 weeks the patient will take place for a 10.000lux lamp for 20-30 minutes.
Study: NCT04801251

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Echocardiographic examination
Description: Each patient included will undergo full cardiac physical examination and echocardiographic examination

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Echocardiographic examination
Description: Each patient included will undergo full cardiac physical examination and echocardiographic examination
Study: NCT05681117

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: multi-component nutrition education
Description: Classroom-based nutrition education 40 minutes once a week for 4 weeks~SMS Reminders SMS reminders containing healthy nutrition tips 2 times a week, 1 weekday, 1 weekend, starting with nutrition education and throughout the education (4 weeks)~Brochure Distribution Brochures prepared in accordance with the content of classroom-based nutrition education were distributed immediately after the nutrition education.~Controversial Supermarket Tour Nutrition label reading activity aimed at gaining the ability to evaluate product contents, in line with the information explained in module 4, in the supermarket tour planned to be organized once with an appropriate number of student groups (maximum 7 people) after the nutrition education
Study: NCT05444699

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone Sodium Phosphate
Description: Oral suspension administered 1 mg/kg once a day for three days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sugar syrup
Description: Oral suspension administered the same amount in milliliters as experimental product once a day for three days
Study: NCT05660629

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan Mobilization
Description: Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mulligan Mobilization
Description: Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier.
Study: NCT04767464

Intervention type: OTHER
Group type: OTHER
Intervention: Compass Course
Description: The Compass Course is an 8-session group course designed to address purpose in life of those with Breast Cancer. Enrollment in this arm will involve participation in the Compass Course virtually.
Study: NCT05551390

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: one-time umbilical cord milking
Description: Before UCM procedures, in the case of vaginal delivery, the maternity doctor or nurse held the newborn below the level of the introitus. In the case of a cesarean section, the surgeon carries the newborn below the level of the incision.~Then maternity nurse or doctor swiped blood in length 20 centimeters of umbilical cord into the newborn, according to the number of swipes that assigned, then cutting the umbilical cord by the international standard methods. Newborns after birth were cared for and assessed according to the newborn nursing standards of QSMH in the department of pediatrics.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: three-times umbilical cord milking
Description: Before UCM procedures, in the case of vaginal delivery, the maternity doctor or nurse held the newborn below the level of the introitus. In the case of a cesarean section, the surgeon carries the newborn below the level of the incision.~Then maternity nurse or doctor swiped blood in length 20 centimeters of umbilical cord into the newborn, according to the number of swipes that assigned, then cutting the umbilical cord by the international standard methods. Newborns after birth were cared for and assessed according to the newborn nursing standards of QSMH in the department of pediatrics.
Study: NCT06139926

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine administered intranasally
Description: Intranasal administration of dexmedetomidine (plain) was given at the bedside of the ward as per the pre-tested recommended dose. The patient's vital signs were maintained. On the day of surgery, 30 min before induction of anesthesia, intranasal dexmedetomidine (original solution) was administered in the operating room at the pre-tested recommended dose.

Intervention type: DRUG
Group type: OTHER
Intervention: Dexmedetomidine administered intranasally
Description: Intranasal administration of dexmedetomidine (plain) was given at the bedside of the ward as per the pre-tested recommended dose. The patient's vital signs were maintained. On the day of surgery, 30 min before induction of anesthesia, intranasal dexmedetomidine (original solution) was administered in the operating room at the pre-tested recommended dose.