TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05383495

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Intranasal dexmedetomidine 3 mcg/kg \[100 mcg/mL (max 200 mcg or 2 mL)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam Nasal Spray
Description: Intranasal midazolam 0.4 mg/kg \[5 mg/mL (max 10 mg or 2 mL)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitrous oxide
Description: 50% nitrous oxide in 50% oxygen by face mask
Study: NCT06109064

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decetabine
Description: Patients will be treated with Decetabine (20mg/m\^2/d on days 1 to 5) or Azacitidine (75mg/m\^2/d on days 1 to 7)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Patients will be treated with Decetabine (20mg/m\^2/d on days 1 to 5) or Azacitidine (75mg/m\^2/d on days 1 to 7)
Study: NCT05263427

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TOCONAUTE
Description: This study will be carried out during delivery. The will be placed on the mother's abdomen to capture fetal and maternal heart rate as well as the uterine contractions in parallel of the cardiotocograph.~For each of the participants, the TOCONAUTE will remain on the mother's abdomen till childbirth. This procedure will not affect the usual care of the patient.
Study: NCT06138769

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Lenvatinib 12 mg (body weight 60 kg or greater) or 8 mg (body weight \< 60 kg) once orally every day
Study: NCT06457867

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: microfragmented adipose tissue loaded on bovine graft
Description: microfragmented adipose tissue loaded on bovine graft on ridge preservation

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: microfragmented adipose tissue loaded on bovine graft
Description: microfragmented adipose tissue loaded on bovine graft on ridge preservation
Study: NCT05575362

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group A
Description: Group A will receive Epleys maneuver and Cawthorne Cooksey exercise for two weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group B
Description: Group B will receive Half Somersault maneuver along with Cawthorne Cooksey exercise for two weeks.
Study: NCT06529913

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Collection of environmental, biological, and clinical data
Description: All enrolled patients/healthy volunteers will undergo:~* measurement of serum and urine concentration of metals (nickel, cobalt, chromium, palladium, molybdenum, aluminium, and copper).~* Patch test to metals.~* Within-breath analysis of oscillometry parameters.~* Measurement of serum zonulin.~* Measurement of serum levels of protein oxidation products.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Collection of environmental, biological, and clinical data
Description: All enrolled patients/healthy volunteers will undergo:~* measurement of serum and urine concentration of metals (nickel, cobalt, chromium, palladium, molybdenum, aluminium, and copper).~* Patch test to metals.~* Within-breath analysis of oscillometry parameters.~* Measurement of serum zonulin.~* Measurement of serum levels of protein oxidation products.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Collection of environmental, biological, and clinical data
Description: All enrolled patients/healthy volunteers will undergo:~* measurement of serum and urine concentration of metals (nickel, cobalt, chromium, palladium, molybdenum, aluminium, and copper).~* Patch test to metals.~* Within-breath analysis of oscillometry parameters.~* Measurement of serum zonulin.~* Measurement of serum levels of protein oxidation products.
Study: NCT05054426

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: intravenous versus intrathecal methotrexate

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: intravenous versus intrathecal methotrexate
Study: NCT06333665

Intervention type: OTHER
Intervention: Whether there is type 2 diabetes mellitus before surgery
Description: Patients were grouped according to whether they had type 2 diabetes mellitus before surgery
Study: NCT06278766

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-552
Description: Oral Solution
Study: NCT04644211

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Pill taken by mouth.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Pill taken by mouth.
Study: NCT05142683

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment As Usual
Description: Various typical interventions for adolescents with depression.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CARIBOU-2
Description: Integrated Care Pathway intervention for adolescents with depression.
Study: NCT06244888

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention Targeting Stress and Emotion Regulation
Description: This intervention involves learning and practicing relaxation exercises and setting aside time for pleasurable activities.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention Targeting Motivation and Self-efficacy for Weight Management
Description: This intervention involves identifying values related to weight, lifestyle, and health; identifying barriers to value-consistent living; exploring the consequences of letting barriers drive behavior; and 4) setting goals that are small, specific, attainable, and values-consistent.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention for Normalization of Eating
Description: This intervention involves dietary self-monitoring with the goal of staying within a calorie goal ranging from 1,200 kcal/day to 1,800 kcal/day. Participants are also provided with meal planning tools and encouraged to addresses hunger and cravings by promoting feelings of satiety via consumption of foods that are high in volume but low in calories.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention Targeting Physical Activity and Sleep
Description: This simple intervention prompts participants at the start of the day to schedule up to 30 minutes of moderate-to-vigorous intensity physical activity; brisk walking is encouraged. Participants also set a bedtime and wake time and are encouraged to set a reminder alarm to ensure at least 8 hours of sleep.
Study: NCT04698499

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swallowing exercise from home
Description: Treatment Arm A will consist of using pen and paper to complete the exercises. This is considered standard care. Treatment Arm B will consist of using Mobili-T to complete the exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Swallowing exercise from home
Description: Treatment Arm A will consist of using pen and paper to complete the exercises. This is considered standard care. Treatment Arm B will consist of using Mobili-T to complete the exercises.
Study: NCT06493448

Intervention type: OTHER
Intervention: observation
Description: This is an observational study.

Intervention type: OTHER
Intervention: observation
Description: This is an observational study.

Intervention type: OTHER
Intervention: observation
Description: This is an observational study.
Study: NCT05195385

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Low-dose computed tomography of the chest
Description: Baseline low dose Ct acquisition, then at 1 year and 2 years to depict suspicious lung nodules
Study: NCT05169866

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nifekalant
Description: Patients identified with new-onset atrial fibrillation with a sustained duration of greater than 1 minutes and less than 48 hours will be considered for the study. Patients randomized to nifekalant arm will receive a bolus of 0.3mg/kg IV in the first 5 minutes and a maintenance dose of 0.2-0.4mg/kg/h for 24 hours.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amiodarone
Description: Patients identified with new-onset atrial fibrillation with a sustained duration of greater than 1 minutes and less than 48 hours will be considered for the study. Patients randomized to amiodarone arm will receive a bolus of 150mg IV in the first 10 minutes and a maintenance dose of 0.5-1mg/min for 24 hours.
Study: NCT03664271

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: in-clinic video intervention
Description: Video with information about eczema and eczema treatment, to be watched in clinic and at home

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: at home video intervention
Description: Video with information about eczema and eczema treatment, to be watched at home only
Study: NCT05461742

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity intervention
Description: While the final content and structure of the intervention will be informed by community advisory board, participants will receive a culturally adapted, Social Cognitive Theory and Transtheoretical Model-based PA intervention. The evidence-based, theory guided aerobic physical activity intervention will systematically build upon the investigators' prior studies and includes the following components: goal setting, in-person physical activity sessions, and written materials.
Study: NCT04801069

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nocturnal Ventilation
Description: AirCurve 10CS PaceWave (Resmed)
Study: NCT06018233

Intervention type: OTHER
Intervention: New proposal for regime creation
Description: Interviews and building of proposals in the light of the information obtained and desk based research
Study: NCT05531981

Intervention type: OTHER
Intervention: detect HPV E7 ctDNA
Description: Peripheral blood was collected from the patients, and the copy number of HPV E7 gene in ctDNA was accurately detected by ddPCR

Intervention type: OTHER
Intervention: detect HPV E7 ctDNA
Description: Peripheral blood was collected from the patients, and the copy number of HPV E7 gene in ctDNA was accurately detected by ddPCR
Study: NCT06206460

Intervention type: OTHER
Intervention: Online Assessment
Description: Online Assessment which consists of:~* Sociodemographic data (life changes, medical and gynaecological history)~* German PMS symptom diary retrospectively for last menstrual cycle~* Quality of Life Inventory (SF-12)~* Expectancy of relief

Intervention type: OTHER
Intervention: Online Assessment
Description: Online Assessment which consists of:~* Sociodemographic data (life changes, medical and gynaecological history)~* German PMS symptom diary retrospectively for last menstrual cycle~* Quality of Life Inventory (SF-12)~* Expectancy of relief
Study: NCT05263557

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dehydroepiandrosterone (DHEA)
Description: Dehydroepiandrosterone (DHEA) at a dose of 150mg once daily for 7 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 11-ketoandrostenedione (11KA4)
Description: 11ketoandrostenedione (11KA4) at a doses of 150mg once daily for 7 days.
Study: NCT05759494

Intervention type: DIAGNOSTIC_TEST
Intervention: rapid diagnostic test (multiplex PCR filmArray)
Description: novel diagnostic platform, the FilmArray®, which combines automated sample preparation, nucleic acid extraction and PCR-based detection of 31 separate targets from a single unprocessed sample in one hour. It combines nesting and multiplexing of the PCR (referred to here as nested multiplex or nmPCR) together with DNA melting curve analysis.
Study: NCT04756804

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 70% v/v Isopropyl Alcohol Surgical Solution
Description: Patient preoperative skin preparation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol
Description: Patient preoperative skin preparation
Study: NCT04648683

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Individual telehealth mindfulness
Description: Participants who enroll and complete lumbar spine surgery will participate in a one-on-one telehealth-delivered (online with audio and video) mindfulness intervention with a trained mindfulness therapist. The intervention is adapted from mindfulness-based cognitive therapy and includes eight, weekly sessions lasting 75 minutes each (except the first session which lasts 90 minutes).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group telehealth mindfulness
Description: Participants who enroll and complete lumbar spine surgery will participate in a group-delivered telehealth (online with audio and video) mindfulness intervention with a trained mindfulness therapist. The intervention is adapted from mindfulness-based cognitive therapy and includes eight, weekly sessions lasting 90 minutes each.
Study: NCT05898724

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blank group
Description: include six orthodontic patients, which have a surgical procedure to install two orthodontic titanium miniscrews in the two lateral parts of the maxilla of each patient, so this group will include 12 installed orthodontic titanium miniscrews.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Silver hydroxyapatite
Description: include six orthodontic patients, which have a surgical procedure to install two silver hydroxyapatite nano-coated orthodontic titanium miniscrews in the two lateral parts of the maxilla of each patient, so this group will include 12 installed silver hydroxyapatite nano-coated orthodontic titanium miniscrews.
Study: NCT05287178

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DBT Skills + Parent Training
Description: The DBT Skills +PT group intervention integrates DBT Skills, Parent Management Training (PMT), and Emotion Coaching (EC). Each session includes a mindfulness practice, homework review to discuss use of skills previously learned, didactics to learn a new set of DBT and PT skills, and assignment of homework. The DBT Skills portions cover the four modules of traditional DBT Skills: Mindfulness, Emotion Regulation, Distress Tolerance (including skills specifically focused on managing difficulties with addiction), and Interpersonal Effectiveness. PT skills include both PMT and EC components such as: praise, use of parental attention to reward positive behavior, reward systems, effective commands and consequences, psychoeducation on children's emotional development, teaching children to label emotions, validating children's emotions, and handling children's negative emotions, and fostering positive emotions.
Study: NCT03922048

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: Single-dose instillation of approximately 0.17 mL/kg (total dose does not exceed 10.5 mL) of HTX-011.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl
Description: Bupivacaine HCl 0.25% (without epinephrine) (total dose not to exceed 75 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl
Description: Bupivacaine HCl 0.25% (without epinephrine) (total dose not to exceed 75 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl
Description: Bupivacaine HCl 0.25% (without epinephrine) (total dose not to exceed 75 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl
Description: Bupivacaine HCl 0.25% (without epinephrine) (total dose not to exceed 75 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl
Description: Bupivacaine HCl 0.25% (without epinephrine) (total dose not to exceed 75 mg).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: Dose to be determined from Cohort 1.
Study: NCT05898724

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Zinc oxide
Description: include six orthodontic patients, which have a surgical procedure to install two zinc oxide nano-coated orthodontic titanium miniscrews in the two lateral parts of the maxilla of each patient, so this group will include 12 installed zinc oxide nano-coated orthodontic titanium miniscrews.
Study: NCT06394310

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dry needling
Description: The dry needling technique will employ in the current proposed study follows the standard technique for needling patients with spasticity
Study: NCT03922048

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: Dose to be determined from Cohort 1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: Dose to be determined from Cohorts 1 and 2.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: Dose to be determined from Cohort 1 Part A.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Luer Lock Applicator
Description: Applicator for instillation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Luer Lock Applicator
Description: Applicator for instillation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Luer Lock Applicator
Description: Applicator for instillation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Luer Lock Applicator
Description: Applicator for instillation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Luer Lock Applicator
Description: Applicator for instillation.
Study: NCT05075109

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Frequency TENS
Description: 30 minutes of high frequency TENS (100 Hz, 200 us) over the muscle belly of triceps and wrist extensors, for 5 days per week over 8 weeks combined with task related training.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Frequency TENS
Description: 30 minutes of low frequency TENS (20 Hz, 0.2 us) over the muscle belly of triceps and wrist extensors, for 5 days per week over 8 weeks. And combined with 30 minutes of TRT.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Task Related Training
Description: Each session of TRT would include:~1. postural control, 2. shoulder mobilization, 3. weight bearing exercises 4. Functional activities that will comprise of simple tasks to more advanced movement patterns as follows:~* Reaching activities~  1. Forward supported reach with cane on tabletop~ 2. Reaching against gravity~ 3. Reaching overhead with active wrist/hand movements~ 4. Dynamic reaching to target e.g. catch a ball~* Grasping, holding and release~  1. Grasp, hold and release objects with gravity minimized~ 2. Pick up and move/release small objects on table~ 3. Pick up and move/release large objects without proximal support~ 4. Incorporate pinch grips in hold and release including stacking, lifting and overhead activity~* Upper limb ADL~  1. Brushing hair, putting on scarf~ 2. Opening bottles, turning off water tap~ 3. Writing, drawing~ 4. Folding of towels, hanging towels and setting table~ 5. Self-feeding
Study: NCT06394310

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham dry needling
Description: In the control group, The investigators will use the methods proposed by Cushman et al. to apply sham dry needling (DN) to our participants
Study: NCT06187207

Intervention type: DIAGNOSTIC_TEST
Intervention: Hand acceleration time (HAT) measurement
Description: Hand Duplex Ultrasound to measure the Hand Acceleration Time (HAT)
Study: NCT05352230

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Free style libre-2
Description: A cross-over design will allow estimation of feasibility and acceptability of patients using CGM vs patients using blood glucose meter monitoring (conventional therapy). The study will consist on two phases, the first will last three months, then it will be a two months of washout period followed by the crossover, then the second phase will last another three months. Patients in the conventional therapy group will also use masked CGM (CGM professional) during the first two and last two weeks of their study phase with the purpose of collecting CGM-parameters information. The cross over randomization will be stratified by donor type (live vs deceased) using a web-based randomization tool. During the washout period the patients will continue using blood glucose meter monitoring

Intervention type: DEVICE
Group type: OTHER
Intervention: Free style libre-2
Description: A cross-over design will allow estimation of feasibility and acceptability of patients using CGM vs patients using blood glucose meter monitoring (conventional therapy). The study will consist on two phases, the first will last three months, then it will be a two months of washout period followed by the crossover, then the second phase will last another three months. Patients in the conventional therapy group will also use masked CGM (CGM professional) during the first two and last two weeks of their study phase with the purpose of collecting CGM-parameters information. The cross over randomization will be stratified by donor type (live vs deceased) using a web-based randomization tool. During the washout period the patients will continue using blood glucose meter monitoring
Study: NCT04904250

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Emboshield
Description: a distall occlusion Emboshield NAV6 will be used as the embolism protection device during CAS

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Spider
Description: a distal SpiderFX will be used as the embolism protection device during CAS
Study: NCT04748107

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Impendence Cardiography
Description: ICG is a noninvasive method of determining the amount of blood flow using the Non-Invasive Cardiac System - Cardiac Surveyor (NICaS) system, which provides an assessment of the cardiovascular system, respiratory system, and fluid retention.