TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06374875

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Metabolic surgery
Description: Patients receive either RYGB or SG. The surgical risk, differential impact of each procedure on body weight and other obesity-related diseases, presence of other medical and mental problems, patient's behavioral factors (e.g., postoperative compliance, active smoking), medications, and goals will be considered when the patient and local medical team make a shared decision about the most appropriate surgical procedure

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Incretin-Based Therapy
Description: Three incretin-based medications that have been approved for treatment of obesity including liraglutide, semaglutide, or tirzepatide will be used in the nonsurgical group. Any of these 3 medications (in the injection or oral from) based on availability in each country, access, and clinical indications can be used. If possible, patients will be placed on high-dose tirzepatide (Mounjaro or Zepbound 15 mg once weekly injection) or high-dose semaglutide (Wegovy 2.4 mg once weekly injection or Ozempic 2 mg once weekly injection). Other acceptable, less preferrable, options: liraglutide (Saxenda or Victoza), semaglutide tablet (Rybelsus), or lower dose of tirzepatide and semaglutide injections.
Study: NCT05948475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tinengotinib 8 mg
Description: Subjects randomized to receive tinengotinib will receive a starting dose of either 8 mg QD., self-administered orally QD in 28-day cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tinengotinib 10 mg
Description: Subjects randomized to receive tinengotinib will receive a starting dose of either10 mg QD., self-administered orally QD in 28-day cycles.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Physician's Choice
Description: For subjects receiving FOLFOX or FOLFIRI, the subject will receive treatment every two weeks, with two administrations per each 28-day cycle.
Study: NCT05891340

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Respiratory muscle exercise
Description: respiratory muscle exercise with inspiratory muscle trainer (two times a day)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Endurance exercise
Description: walking exercise 5000 steps/day
Study: NCT04667000

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Forced Air Warming
Description: We will use Forced Air Warming for cesarean patient

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Forced Air Warming
Description: We will use Forced Air Warming for cesarean patient

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Forced Air Warming
Description: We will use Forced Air Warming for cesarean patient
Study: NCT05538520

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Pilates
Description: This group will perform a traditional Pilates session, which consists of stretching exercises, followed by exercises to strengthen the core (trunk flexors and extensors), lower limbs and upper limbs. The total duration of the intervention in this group should be approximately 50 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates without stretching
Description: This group will conduct a non-traditional Pilates session. This is because stretching exercises will be excluded. The muscle strengthening exercises will be the same as in the TP group, so that it is possible to discuss the influence of the inclusion/exclusion of stretching for the considered outcomes. The total duration of the intervention in this group should be approximately 35 minutes.
Study: NCT06010771

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Listening to fairy tales
Description: Fairy tales by children will be chosen by child psychologists. Tales will be read to the children by the researcher. The researcher has a fairy tale therapy certificate. The tale reading will start 5 minutes before the aspiration process and will continue throughout the aspiration process. Tales will be read to children every other day. This process will continue for 3 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Watching Cartoon Film
Description: The cartoons that children will watch will be preferred by child psychologists. Children will be watched cartoons with the help of tablets. Watching cartoons will start 5 minutes before the aspiration process and will continue throughout the aspiration process. Children will be shown cartoons every other day. This process will continue for 3 weeks.
Study: NCT06057584

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: somatosensory-motor integration training
Description: Participants will use both hands to perform functional tasks requiring somatosensory discrimination to provide different somatosensory stimuli to facilitate motor control. The experimental group will receive somatosensory-motor integration training, 3-5 sessions a week, for a total of 15 sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: pure somatosensory training
Description: Participants will use the affected hand to perform somatosensory discrimination tasks, including limb position discrimination and object discrimination.The experimental group will receive pure somatosensory integration training, 3-5 sessions a week, for a total of 15 sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: pure motor training
Description: Participants will conduct bilateral task-oriented training, but the training task does not require somatosensory discrimination. Each round only uses the same target and target position to repeatedly practice the functional task movements, but the target or target position is different in different rounds. The experimental group will receive pure motor integration training, 3-5 sessions a week, for a total of 15 sessions.
Study: NCT06273670

Intervention type: OTHER
Intervention: screening and data collection
Description: Structured questionnaire prepared in English and translated to local language (Arabic). The questionnaire is then linguistically validated by two forwards translations and one backward translation. Data was collected by the investigators who were not participating in the study.~Personal or telephone interview will be conducted with clients and service providers conducted to collect the data.

Intervention type: OTHER
Intervention: screening and data collection
Description: Structured questionnaire prepared in English and translated to local language (Arabic). The questionnaire is then linguistically validated by two forwards translations and one backward translation. Data was collected by the investigators who were not participating in the study.~Personal or telephone interview will be conducted with clients and service providers conducted to collect the data.
Study: NCT05380258

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stress ball
Description: Pregnant women with 4-5 cm cervical dilatation were asked to tighten the ball for 5 seconds and relax for 2 seconds within 20 minutes when their contractions came, and when the cervical opening was 6-8 cm, they were asked to tighten the ball for 5 seconds and relax for 2 seconds within 20 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chewing gum
Description: Pregnant women with 4-5 cm cervical dilatation were asked to squeeze the ball for 5 seconds and loosen it for 2 seconds as soon as their contractions came and within 20 minutes, and when the cervical opening was 6-8 cm, they chewed gum again for 20 minutes.
Study: NCT05529849

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCMCB07
Description: Subcutaneous injection of TCMCB07

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching subcutaneous placebo
Study: NCT04333745

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Controlled Diet
Description: Participant will consume a controlled low oxalate diet for five days

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carbon-13 Oxalate and Sucralose Ingestion
Description: Subjects will ingest a small amount of carbon-13 oxalate and sucralose, dissolved in water.
Study: NCT05752877

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Targeted IL-13 Rα2 UCAR-T cell injection
Description: local administration (intracranial cavity or intravertebral injection after surgery): 1 ampoule (about 2-5 ml, 1-5×10\^7 cells) for 1-2 minutes each time.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Targeted B7-H3 UCAR-T cell injection
Description: local administration (intracranial cavity or intravertebral injection after surgery): 1 ampoule (about 2-5 ml, 1-5×10\^7 cells) for 1-2 minutes each time.
Study: NCT05676619

Intervention type: DEVICE
Group type: OTHER
Intervention: 3D foot scanner
Description: Reliability of 3D foot scanner during repeated scans
Study: NCT06411080

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound evaluation of fluid tolerance
Description: Lung ultrasound for the assessment of B-line artifact and pleural effusion combined with abdominal ultrasound for VExUS assessment. The imaging study will be reviewed by an expert for will generate a report with interpretation regarding the risk of fluid administration. The assessment will be performed at baseline and after 48 hours after randomization.
Study: NCT06360991

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Deep brain stimulation (DBS)
Description: The DBS lead is stereotactically introduced into the target in the brain (vALIC, BNST, amSTN, VC/VS, or NAc) and fixed to the skull; the lead is then connected to a neurostimulator implanted subcutaneously in the subclavicular region.
Study: NCT05738811

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TENS treatment protocol
Description: The 2 sets of electrodes of TENS were placed over the common peroneal nerve as it passes over the head of fibula and the motor point of tibialis anterior to elicit dorsiflexion and eversion of foot.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EMS treatment protocol
Description: The electrodes were placed over the common peroneal nerve as it passes over the head of fibula and the motor point of tibialis anterior to elicit dorsiflexion and eversion of foot. A portable comfy EMS channel was used to apply EMS protocol to set at threshold of muscle contraction level.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercises
Description: Patient were given 30 minutes treatment session, 10 minutes of supported walking 10 minutes of BWS treadmill training 10 minutes of Task-specific over ground locomotor training (LT) There was rest of 2 minutes The frequency of the sessions was five times a week for 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercises
Description: Patient were given 30 minutes treatment session, 10 minutes of supported walking 10 minutes of BWS treadmill training 10 minutes of Task-specific over ground locomotor training (LT) There was rest of 2 minutes The frequency of the sessions was five times a week for 12 weeks.
Study: NCT06174051

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Flashforward EMDR
Description: The Flashforward procedure in EMDR-treatment aims to reduce fear evoked by images of imagined future adverse events.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Flashback EMDR
Description: The Flashback procedure in EMDR-treatment aims to successfuly process the memories of traumatic events that happened in the past.
Study: NCT05629429

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: Olaparib 300mg BID PO

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy drug
Description: Continue platinum based chemotherapy
Study: NCT04993534

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stepped-care DWM/PM+
Description: The DWM program consists of a self-help guide that is complemented with pre-recorded audio exercises. The audio material imparts key information about stress management and guides participants through individual exercises. Additionally, participants are guided by a briefly trained helper. DWM includes five sections (or modules), each of which focuses on a specific skill. In this study, the DWM program will be delivered as an online intervention. The DWM intervention, i.e. both the audios and the self-help guide, have been adapted for use on a smartphone or other device with internet access.~PM+ is a new, brief, psychological intervention program based on cognitive-behavioral therapy (CBT) techniques. The manual involves the following empirically supported elements: problem solving plus stress management, behavioral activation, facing fears, and accessing social support.

Intervention type: OTHER
Group type: OTHER
Intervention: Psychological First Aid + usual care (CAU)
Description: All participants, both in the treatment and the comparison group, will be offered individual Psychological First Aid (PFA) through a face-to-face or teleconferencing meeting. In addition to PFA, both the treatment and the comparison group will receive care-as-usual (CAU); they will be allowed to receive any usual care. CAU may include community care, social/legal support, and psychoeducation.
Study: NCT05138666

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: respiratory sample
Description: tracheal aspirate or sputum if the patient is not intubated

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood sample
Description: Blood sampling drawn from an existing arterial line twice a week
Study: NCT06292572

Intervention type: PROCEDURE
Intervention: Retinal Detachment Surgery
Description: Retinal Detachment Surgery that consists in either Pars Plana Vitrectomy or Scleral Buckling or a combination of both techniques, and with or without use of intraocular tamponade

Intervention type: PROCEDURE
Intervention: Retinal Detachment Surgery
Description: Retinal Detachment Surgery that consists in either Pars Plana Vitrectomy or Scleral Buckling or a combination of both techniques, and with or without use of intraocular tamponade
Study: NCT05147064

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: minimally invasive surgery
Description: using (tubular dilators, surgical microscope, and/ or endoscope). the other group will be operated by conventional inter laminar decompression.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: conventional open surgery
Description: open interlaminar lumbar decompression
Study: NCT06086093

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: RespireAid TM/placebo
Description: Direction: Take 1 sachet(5g) 4 times daily~Indication: Externally contracted seasonal epidemic~Function: Relieving Exterior and Facilitating Lung, clear heat of lung, Wide chest and resolve phlegm

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: RespireAid TM/placebo
Description: Direction: Take 1 sachet(5g) 4 times daily~Indication: Externally contracted seasonal epidemic~Function: Relieving Exterior and Facilitating Lung, clear heat of lung, Wide chest and resolve phlegm
Study: NCT04901481

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Empower Neuromodulation System
Description: Peripheral nerve stimulation with the Empower device. The active and sham treatments only differ by the location of application on the body.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Empower Neuromodulation System
Description: Peripheral nerve stimulation with the Empower device. The active and sham treatments only differ by the location of application on the body.
Study: NCT04572880

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Trabeculectomy
Description: Trabeculectomy is performed

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: XEN®
Description: Microinvasive Surgery with XEN® is performed

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Preserflo®
Description: Microinvasive Surgery with Preserflo® is performed
Study: NCT05765266

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACP Max™
Description: Single 4-6 ml intra-articular (IA) injection of the output of ACP Max™

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Depo-Medrol®
Description: Single IA injection of 40 mg of methylprednisolone acetate (1 ml of solution) mixed with 5 ml of Normal Saline for a total of 6 ml.
Study: NCT05407597

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Icatibant
Description: Solution for injection, 30mg (3mls) administered as a single subcutaneous injection~SARS CoV-2 patients will receive all supportive treatment and medications that are used as standard of care including but not limited to Dexamethasone, Remdesivir, Tocilizumab and antibiotics.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% Sodium Chloride Injection
Description: Solution for injection (3mls) administered as a single subcutaneous injection~SARS CoV-2 patients will receive all supportive treatment and medications that are used as standard of care including but not limited to Dexamethasone, Remdesivir, Tocilizumab and antibiotics.
Study: NCT06368167

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2554
Description: SHR2554
Study: NCT05799599

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stay-Play-Talk Basic
Description: Stay-Play-Talk (SPT) Basic and SGD with augmented peer input in which peers are taught to model verbal responses while simultaneously selecting screen icons with spoken peer input only (i.e., peers taught to model language)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stay-Play-Talk Basic
Description: Stay-Play-Talk (SPT) Basic and SGD with augmented peer input in which peers are taught to model verbal responses while simultaneously selecting screen icons with spoken peer input only (i.e., peers taught to model language)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stay-Play-Talk Basic
Description: Stay-Play-Talk (SPT) Basic and SGD with augmented peer input in which peers are taught to model verbal responses while simultaneously selecting screen icons with spoken peer input only (i.e., peers taught to model language)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stay-Play-Talk Plus
Description: SPT Plus with augmented SGD peer input (i.e., peers taught to use verbal language models concurrently while selecting SGD icons).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stay-Play-Talk Plus
Description: SPT Plus with augmented SGD peer input (i.e., peers taught to use verbal language models concurrently while selecting SGD icons).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stay-Play-Talk Plus
Description: SPT Plus with augmented SGD peer input (i.e., peers taught to use verbal language models concurrently while selecting SGD icons).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stay-Play-Talk Plus
Description: SPT Plus with augmented SGD peer input (i.e., peers taught to use verbal language models concurrently while selecting SGD icons).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stay-Play-Talk Advanced
Description: SPT Advanced adds direct instruction strategies for the children with ASD (i.e., adult prompts, reinforcers, and embedded teaching trials) to increase peer-directed communication.
Study: NCT05132374

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: I-T CHILD
Description: This study will evaluate the I-T CHILD's application in early childhood mental health consultation services provided to family/group family child care programs
Study: NCT05424757

Intervention type: DRUG
Intervention: PEG 3350
Description: Data and biospecimens will be collected from two groups of children:~* Children who have taken PEG 3350 daily for at least 30 days.~* Children who have NOT taken PEG 3350 for at least 30 days.~No changes to medicines are recommended as part of this study.
Study: NCT05900388

Intervention type: DRUG
Intervention: Rivaroxaban (Xarelto, BAY59-7939)
Description: Retrospective cohort analysis using National health registers in Denmark and Sweden; Système National Des Données De Santé (SNDS) in France and Sistema d'Informació per al Desenvolupament de l'Investigació en Atenció Primària (SIDIAP) in Spain

Intervention type: DRUG
Intervention: Standard of care (SOC)
Description: Retrospective cohort analysis using National health registers in Denmark and Sweden; Système National Des Données De Santé (SNDS) in France and Sistema d'Informació per al Desenvolupament de l'Investigació en Atenció Primària (SIDIAP) in Spain. SOC including heparins, Vitamin K antagonists (VKAs) and Other Direct oral anticoagulants (DOACs).
Study: NCT06026748

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XJ103 Injection
Description: XJ103 is a humanized monoclonal antibody.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo contains only excipients.
Study: NCT06197334

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gastro-intestinal biopotentials recording
Description: Participants will undertake two recordings made with the device. The first one will last 1 hour and 30 minutes and will occurs while the participants are fasting. Then, they will eat a standardized meal. Finally, the second recording will take place after the meal ingestion and will last 1 hour and 30 minutes while the participants are in postprandial state.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gastro-intestinal biopotentials recording
Description: Participants will undertake two recordings made with the device. The first one will last 1 hour and 30 minutes and will occurs while the participants are fasting. Then, they will eat a standardized meal. Finally, the second recording will take place after the meal ingestion and will last 1 hour and 30 minutes while the participants are in postprandial state.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gastro-intestinal biopotentials recording
Description: Participants will undertake two recordings made with the device. The first one will last 1 hour and 30 minutes and will occurs while the participants are fasting. Then, they will eat a standardized meal. Finally, the second recording will take place after the meal ingestion and will last 1 hour and 30 minutes while the participants are in postprandial state.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gastro-intestinal biopotentials recording
Description: Participants will undertake two recordings made with the device. The first one will last 1 hour and 30 minutes and will occurs while the participants are fasting. Then, they will eat a standardized meal. Finally, the second recording will take place after the meal ingestion and will last 1 hour and 30 minutes while the participants are in postprandial state.
Study: NCT06030336

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Health Report
Description: The Home Health Report has been described in the intervention arm description.
Study: NCT05149664

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Therapeutic ultrasound (TUS)
Description: As described elsewhere, a sleeve is wrapped around the subject's targeted calf such that the inner lining with attached transducers are positioned around the calf muscle, with a gel-skin interface. The ultrasound energy is transmitted from these transducers to the deeper layers of the muscle.