TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06217055

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: general anesthesia with sevoflurane
Description: The surgery will be performed under mechanical ventilation with inhalation general anesthesia
Study: NCT04958525

Intervention type: PROCEDURE
Intervention: Keyhole neuroendoscopic transfrontal ultrasound-guided hematoma removal
Description: Keyhole neuroendoscopic transfrontal ultrasound-guided hematoma removal in basal ganglia region:According to the brain CT scan and reconstruct the operation plan, choose a side by 2 cm before the coronal suture line 4 cm and 3 cm center longitudinal incision formation of 2 cm bone drilling the hole, ultrasonic measurement and the size of hematoma puncture depth, and guide the puncture direction, the transparent channel under endoscopic direct placement hematoma backend, after entering the hematoma cavity, under the neural endoscopic removal of hematoma,Wash the hematoma cavity with warm salt water.Bipolar electrocoagulation hemostasis for active bleeding.An indwelling drainage tube was placed in the hematoma cavity, and ultrasonography determined that the hematoma was cleared satisfily without active bleeding.

Intervention type: PROCEDURE
Intervention: Small bone window craniotomy for hematoma removal under microscope
Description: Small bone window craniotomy for hematoma removal under microscope:Small bone window craniotomy in frontotemporal region, no blood vessels and non-functional areas of the hematoma nearest to the cortex was cut open, the hematoma was removed under the microscope and the cavity of the hematoma was washed with warm saline, and bipolar electrocoagulation hemostasis was performed for active bleeding.An indwelling drainage tube was placed in the hematoma cavity and the operation was completed without active bleeding.
Study: NCT06194565

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99mTc-ABH2
Description: Each patient will receive an intravenous injection of 99mTc-ABH2, and undergo a SPECT/CT scan within specified time.
Study: NCT05360381

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX35
Description: A Recombinant Human Anti-EGFR and Anti-4-1BB Bispecific Antibody, HLX35 will be administered as a single intravenous (IV) infusion on Day 1 in each 14-day cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX35
Description: A Recombinant Human Anti-EGFR and Anti-4-1BB Bispecific Antibody, HLX35 will be administered as a single intravenous (IV) infusion on Day 1 in each 14-day cycle
Study: NCT06243263

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacain
Description: At the end of the surgery, after wound closure, an inferior alveolar nerve block with 2ml bupivacaine 0,5 % will be realized.
Study: NCT05371743

Intervention type: DIAGNOSTIC_TEST
Intervention: Plasma RNA isolation, qPCR analysis of micro RNA
Description: qPCR will be performed using Taqman microRNA assays (Applied Biosystems, Foster City, CA, USA) according to the manufacturer's protocol. Total RNAs going to be used to make cDNAs using TaqMan microRNA RT Kit. Diluted cDNAs were mixed with TaqMan Universal PCR Master Mix (No AmpErase UNG). Taqman miRNA assay will run in the 7500 Real-Time PCR System (Applied Biosystems). miR-39 also will be used as an exogenous control. All assays will be done in triplicates. The expression levels will be evaluated using the comparative cycle threshold (∆∆_Ct) method

Intervention type: DIAGNOSTIC_TEST
Intervention: estimation of serum level of IL2
Description: 2ml of patient serum will be used to measure IL 2 in patients with different groups by ELISA technique.~The techniques will be done in the central research laboratory in Sohag university hospital

Intervention type: DIAGNOSTIC_TEST
Intervention: estimation of serum level of IL17
Description: 2ml of patient serum will be used to measure IL17 in patients with different groups by ELISA technique.~The techniques will be done in the central research laboratory in Sohag university hospital
Study: NCT05770791

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Black Seed ( Nigella Sativa)
Description: Intervention will be given once a day for 1 month, total 30 days Data will be collected at baseline and at the end of the intervention at 30th day

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Cumin Seed (Cuminum Cyminum)
Description: Intervention will be given once a day for 1 month, total 30 days Data will be collected at baseline and at the end of the intervention at 30th day
Study: NCT06201377

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Periodontal Access Surgery+ Suture with chlorhexidine
Description: Periodontal conventional surgery will be performed as treatment of periodontal diseases in patients who present active periodontal pockets. At the end of the surgery, the surgeon will suture the flap with the absorbable polyglactin 910 suture coated with chlorhexidine (Novosyn Chlorhexidine). Standardized post-surgical recommendations will be followed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Periodontal Access Surgery+ Suture without chlorhexidine
Description: Periodontal conventional surgery will be performed as treatment of periodontal diseases in patients who present active periodontal pockets. At the end of the surgery, the surgeon will suture the flap with the absorbable polyglactin 910 suture (Novosyn). Standardized post-surgical recommendations will be followed.
Study: NCT04982315

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard Acupuncture
Description: The standard acupuncture intervention is based on classical Chinese acupuncture therapy. Participants randomized to standard acupuncture will receive up to 15 acupuncture treatments over 3 months with the total number being determined by the patient and acupuncturist together. All treatments will include acupuncture needling only. They will be provided at medical facilities or in private acupuncturists' offices.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Enhanced Acupuncture
Description: The enhanced acupuncture intervention includes the 3 months of standard acupuncture plus an additional 3 months of maintenance acupuncture. Participants randomized to enhanced acupuncture will receive up to 21 acupuncture treatments over 6 months. The maintenance acupuncture treatment sessions are expected to consist of the same intervention used in the first 3 months of care described in the standard acupuncture arm, plus up to 6 treatments during the maintenance phase. All treatments will include acupuncture needling only. They will be provided at medical facilities or in private acupuncturists' offices.
Study: NCT05003180

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical stabilization
Description: The surgical stabilization can be either open or minimally invasive. The recommended procedure is posterior fixation with pedicle screws and rods. Both short and long segment fixation are allowed in the study. It is up to the treating surgeon to decide on fusion or decompression. If feasible, pedicle screws are inserted in the fractured vertebra.
Study: NCT04739319

Intervention type: OTHER
Intervention: N/A Observational study
Description: N/A Observational study
Study: NCT05085093

Intervention type: BIOLOGICAL
Intervention: HPV vaccine
Description: Patients choose to be vaccinated or not to be vaccinated with HPV vaccine according to their own wishes
Study: NCT05287958

Intervention type: DIAGNOSTIC_TEST
Intervention: EIT
Description: EIT comprises a chest belt that is connected to a computer via a universal serial bus (USB) or an Ethernet cable. The chest belt captures EIT data, which is transmitted via the USB or Ethernet cable to the computer. Tomography-like impedance images of the lungs are computed and displayed on the computer. The impedance images will be used to evaluate lung recruitment and other pulmonary function parameters that are currently measured using standard-of-care PFT devices.

Intervention type: DIAGNOSTIC_TEST
Intervention: EIT
Description: EIT comprises a chest belt that is connected to a computer via a universal serial bus (USB) or an Ethernet cable. The chest belt captures EIT data, which is transmitted via the USB or Ethernet cable to the computer. Tomography-like impedance images of the lungs are computed and displayed on the computer. The impedance images will be used to evaluate lung recruitment and other pulmonary function parameters that are currently measured using standard-of-care PFT devices.
Study: NCT05651074

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vicagrel and omeprazole
Description: 18 mg vicagrel capsules and 40 mg omeprazole magnesium enteric-coated tablets
Study: NCT05930912

Intervention type: DIAGNOSTIC_TEST
Intervention: Psychoanalysis
Description: Case-specific psychoanalysis is performed, including the participant's background during birth.

Intervention type: DRUG
Intervention: sertraline 50mg
Description: After the initial assessment of 50 mg/d, the treatment dosage is determined at 100 mg/d.

Intervention type: DRUG
Intervention: Duloxetine 20 MG
Description: Duloxetine is used with 20 mg/night for subsidiary effects with sertraline.

Intervention type: BEHAVIORAL
Intervention: Cognitive Behavioral Therapy
Description: CBT is tailored to the participant's current activities and life decisions.
Study: NCT04725136

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FURESTEM-AD inj
Description: Repeated administration group: 3 times high or low dose at 4 week intervals. Single administration group: 1 time high or low dose, 2 times placebo injection at 4 week intervals Placebo: 3 times placebo injection at 4 week intervals.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FURESTEM-AD inj
Description: Repeated administration group: 3 times high or low dose at 4 week intervals. Single administration group: 1 time high or low dose, 2 times placebo injection at 4 week intervals Placebo: 3 times placebo injection at 4 week intervals.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FURESTEM-AD inj
Description: Repeated administration group: 3 times high or low dose at 4 week intervals. Single administration group: 1 time high or low dose, 2 times placebo injection at 4 week intervals Placebo: 3 times placebo injection at 4 week intervals.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FURESTEM-AD inj
Description: Repeated administration group: 3 times high or low dose at 4 week intervals. Single administration group: 1 time high or low dose, 2 times placebo injection at 4 week intervals Placebo: 3 times placebo injection at 4 week intervals.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: FURESTEM-AD inj
Description: Repeated administration group: 3 times high or low dose at 4 week intervals. Single administration group: 1 time high or low dose, 2 times placebo injection at 4 week intervals Placebo: 3 times placebo injection at 4 week intervals.
Study: NCT05869617

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aquatic exercise
Description: Participants in the aquatic therapy group will receive aquatic therapy in a HydroWorx aquatic therapy pool at Hydrathletics.~In the aquatic therapy group the 20 minutes of aerobic exercise at each visit will involve walking on an underwater treadmill. The intensity of the walking will be determined by the participant at self-selected intensities that are not perceived to cause a lasting increase in pain for one hour after the exercise session.~The 20 minutes of strengthening exercise will focus on movement patterns that simulate common daily functional activities. Initial intensity of exercises will be determined in collaboration between the health professional and patient by testing the intensity of the exercise that allows the participant to perform 8 repetitions without experiencing a lasting increased in pain. Exercise intensity will be increased weekly by either increasing the number of repetitions or increasing resistance.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Land-based Exercise
Description: Traditional land-based training will take place the Hydrathletics gym with similar exercises provided to the aquatic therapy group.~The aerobic exercise for the land-based therapy group will be 20 minutes of treadmill walking. The intensity will be determined by the participant at self-selected intensities that are not perceived to cause a lasting increase in pain for one hour after the exercise session.~The 20 minutes of strengthening exercise will focus on similar movement patterns to the aquatic therapy group to simulate common daily functional activities. Initial intensity of exercises will be determined in collaboration between the health professional and patient by testing the intensity of the exercise that allows the participant to perform 8 repetitions without experiencing a lasting increased in pain. Exercise intensity will be increased weekly by either increasing the number of repetitions or the resistance used for the exercise.
Study: NCT05723666

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group watching virtual reality glasses
Description: A nature video will be watched with virtual reality glasses.
Study: NCT06463041

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental, comparator and control
Description: How does implementing a GetUp Assist device in addition to a daily low-intensity functional or traditional training program affect Norwegian female office workers' physical health after 12 weeks?
Study: NCT06134648

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose L
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose A
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose A
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose A
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose B
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose B
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV/hMPV vaccine candidate Dose B
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection
Study: NCT05004766

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Robot assisted gait training with virtual reality
Description: Using the VR system during robot training, the auditory stimulation of VR was applied along with the image of walking of a forest road or coastal road at the same speed as the robot walking speed. The VR programs are a composition of scenic beaty with sounds of nature. Each program is a blend of scenes such as the ocean, desert, forest, flowers, waterfalls, and wildlife.
Study: NCT06134648

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular Injection
Study: NCT05905224

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Invisalign 7-day wear protocol
Description: Clear Aligners' (Invisalign, Align technology, San Jose, Calif) 7-day wear protocol

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Invisalign 3-day wear protocol
Description: Clear Aligners' (Invisalign, Align technology, San Jose, Calif) 3-day wear protocol
Study: NCT04835220

Intervention type: OTHER
Group type: OTHER
Intervention: Telehealth Calls
Description: The telehealth nurse will record data in a case report form within the VA REDCap electronic data capture system that is stored within the VA firewall.
Study: NCT04897932

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: RS - WP06
Description: Ad hoc use of handheld urinal

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: RS - WP06
Description: Ad hoc use of handheld urinal

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: RS - WP06
Description: Ad hoc use of handheld urinal

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: RS - WP06
Description: Ad hoc use of handheld urinal
Study: NCT06145061

Intervention type: DEVICE
Intervention: all patients and healthy people will receive at least 3 infrared thermal imaging examinations of acupoints and pain threshold examinations of acupoints.
Description: Infrared thermal imaging detection scheme of acupoints:Detection equipment NEC R550 infrared thermal imager.Records the corresponding acupoints coordinates,and starts to collect the infrared thermal image.and 6 images will be taken continuously for each detected part.The infrared thermograms were stored and extract the temperature values of the corresponding coordinates of the acupoints.The average temperature values of the acupoints in the six infrared thermograms were calculated as their temperatures.Pain threshold detection scheme of acupoints:The instrument and equipment use the FDX25 hand-held pain threshold test instrument to explore the acupoints.Place the probe of the pain measuring instrument vertically on the pain measuring acupoint, slowly and steadily press downward at a constant speed, and stop pressing immediately when the subject begins to feel pain. At this point, the reading on the display is the subject's pain threshold. All acupoints shall be measured once in total.

Intervention type: DEVICE
Intervention: all patients and healthy people will receive at least 3 infrared thermal imaging examinations of acupoints and pain threshold examinations of acupoints.
Description: Infrared thermal imaging detection scheme of acupoints:Detection equipment NEC R550 infrared thermal imager.Records the corresponding acupoints coordinates,and starts to collect the infrared thermal image.and 6 images will be taken continuously for each detected part.The infrared thermograms were stored and extract the temperature values of the corresponding coordinates of the acupoints.The average temperature values of the acupoints in the six infrared thermograms were calculated as their temperatures.Pain threshold detection scheme of acupoints:The instrument and equipment use the FDX25 hand-held pain threshold test instrument to explore the acupoints.Place the probe of the pain measuring instrument vertically on the pain measuring acupoint, slowly and steadily press downward at a constant speed, and stop pressing immediately when the subject begins to feel pain. At this point, the reading on the display is the subject's pain threshold. All acupoints shall be measured once in total.
Study: NCT05231395

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inspiratory Muscle Training Group
Description: Patients in the training group will receive inspiratory muscle training with the PowerBreathe® (inspiratory muscle training device) at 50% of the maximal inspiratory pressure.~Patients in the training group inspiratory muscle training will be given 2 sets of 15 minutes a day for a total of 30 minutes/per day or a single session for 30 minutes/week, 7 days/week for a total of 8 weeks.~Patients in the training group will be given respiratory muscle strength training with a home program 6 days a week under the supervision of a physiotherapist 1 day a week.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Control Group
Description: Control group will be given breathing exercises 120 times/day, 7days/week, for 8 weeks as home program.~Control group will be followed-up by telephone once a week
Study: NCT05983679

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample
Description: Blood sample
Study: NCT05848960

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hypercaloric, hyperproteic oral supplement
Description: 2 supplements per day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mediterranean diet
Description: Mediterranean diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: Mediterranean diet
Study: NCT06364306

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Robotically-assisted ventral hernia repair (RVHR)
Description: 3 8mm robotic trocars are placed intraabdominally and the DaVinci Xi-robotic system is docked. Adhesiolysis from any adherent structures to the abdominal wall is performed. Incision of the lateral verge of the retromuscular space and retromuscular dissection. Superior and inferior cross-over to the contralateral retromuscular space and dissection of the hernia sac.~Unilateral or bilateral transversus abdominis release (TAR) is performed, if necessary. Running suture with absorbable barbed suture of the posterior rectus sheath and peritoneum, as appropriate. Synthetic retromuscular mesh placement with a mesh-size as large as the prepared surface allows. Closure of the anterior rectus sheath with absorbable barbed running suture. Port extraction, skin closure. Dressing from xyphoid to pubis and 6 lateral dressings for blinding purposes.
Study: NCT06497933

Intervention type: PROCEDURE
Intervention: Atrial fibrillation ablation
Description: Pulmonary veins isolation potentially associated with other atrial lesions, performed with the pentaspline PFA catheter

Intervention type: PROCEDURE
Intervention: Atrial fibrillation ablation
Description: Pulmonary veins isolation potentially associated with other atrial lesions, performed with the pentaspline PFA catheter

Intervention type: PROCEDURE
Intervention: Atrial fibrillation ablation
Description: Pulmonary veins isolation potentially associated with other atrial lesions, performed with the pentaspline PFA catheter
Study: NCT06364306

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open ventral hernia repair (OVHR)
Description: Median laparotomy with a minimal length of the previous scar (in case of incisional hernia) and adhesiolysis is performed, where necessary, to liberate the abdominal wall and the ventral hernia from adhesions. Bilateral dissection of the posterior rectus sheath under visualisation and sparing of the epigastric vessels and neurovascular bundles. Closure of the posterior rectus sheath with a slowly-absorbable running suture. Indication for a uni- or bilateral TAR identical to the intervention group. Retromuscular synthetic mesh placement with a mesh-size as far as the prepared surface allows. Mesh fixation optional with either absorbable sutures to the posterior sheath or with glubran glue. Closure of the anterior rectus sheath with a slowly-absorbable running suture. Skin closure. Dressing from xyphoid to pubis and 6 lateral dressings for blinding purposes.