TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06546059

Intervention type: DEVICE
Group type: OTHER
Intervention: narrow band ultraviolet-B
Description: vitiligo patients will recevie twice sessions per week
Study: NCT05115708

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ab externo viscotrabeculotomy
Description: In brief, a fornix-based conjunctival incision is followed by fashioning and dissection of a triangular scleral flap. Radial incisions at the limbus followed to identify Schlemm's canal. viscotrabeculotomy, is performed by injection of high-viscosity sodium hyaluronate (Healon GV, Pfizer, NY) into Schlemm's canal prior to completion of the procedure with the metal trabeculotome. while a Nylon 10/0 suture in inserted into schlemm's canal in visco-circumferential-suture trabeculotomy group

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: The Kahook dual blade® (KDB) assisted ab-interno trabeculotomy
Description: The Kahook dual blade® (KDB) assisted ab-interno trabeculotomy
Study: NCT05739539

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: optical coherence tomography angiography
Description: optical coherence tomography angiography will be done postoperatively in both groups to assess the retinal microvascular changes
Study: NCT04710368

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Evolocumab Injections
Description: Administered on day 1 (the day of the first treatment) and through week 26 with a personal injector or prefilled auto injector/pens.
Study: NCT05739539

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: optical coherence tomography angiography
Description: optical coherence tomography angiography will be done postoperatively in both groups to assess the retinal microvascular changes

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: spectral domain optical coherence tomography
Description: optical coherence tomography for ganglion cell complex (GCC) measurement and assessment of macular edema or epiretinal membrane formation will be done postoperatively in both groups

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: spectral domain optical coherence tomography
Description: optical coherence tomography for ganglion cell complex (GCC) measurement and assessment of macular edema or epiretinal membrane formation will be done postoperatively in both groups
Study: NCT05802771

Intervention type: PROCEDURE
Intervention: surgical resection
Description: surgical resection of the lung cancer
Study: NCT05334459

Intervention type: RADIATION
Intervention: radiotherapy
Description: Oligometastatic disease (defined here as 5 or fewer sites of metastatic disease involving 3 or fewer organ systems)~* Primary tumor biopsy, Metastatic site biopsy (Bone, liver, etc) (if there is, based on institutional practice)~  o ER / PR /Her2 /Ki67 study)~* Collection of CTC.~* Radiotherapy (RT) to the primary breast tumor (Hypo fractionated)~* All patients will receive the standard of care treatment with CDK4/6 inhibitor + AI for 6 months (at least 26 weeks).~  o Denosumab, Biphosphonate for bone metastasis~* RT to metastatic side (if visible). Continue Systemic therapy~* 12 months, patients will have LRT surgery (BCS/mastectomy + LN evaluation; SLNB+ALND) + RT (based on the institutional practice). Collect CTC and ER/PR/Her 2 in the final specimen~* ST will be continued until progression and/or unmanageable toxicity.~* Radiologic evaluation every 3-6-month based on institutional practice.
Study: NCT05784922

Intervention type: OTHER
Intervention: Educational Lung Cancer Screening (LCS) Video
Description: An educational video on lung cancer screening tailored to Hispanic current and former smokers.

Intervention type: OTHER
Intervention: Educational Lung Cancer Screening (LCS) Video
Description: An educational video on lung cancer screening tailored to Hispanic current and former smokers.

Intervention type: OTHER
Intervention: Educational Lung Cancer Screening (LCS) Video
Description: An educational video on lung cancer screening tailored to Hispanic current and former smokers.
Study: NCT05874310

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-002
Description: Comparison of different dosages of FT-002

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-002
Description: Comparison of different dosages of FT-002

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-002
Description: Comparison of different dosages of FT-002
Study: NCT05768399

Intervention type: DIAGNOSTIC_TEST
Intervention: The level of biomarkers in Peripheral blood
Description: All participants will be extracted 5ml peripheral blood into the anticoagulant tube by nurses and the peripheral blood will be detected for biomarkers of asthma. Children with asthma will take pulmonary function, blood test and specific IgE test etc. The lung function test will be performed by professional technicians and the results will be interpreted by specialists. The blood test and specific IgE test will be collected by specialist nurses and the results will be issued by professional inspectors. Children with asthma and their guardians will be asked for filling the questionnaire of Childhood Asthma Control Test (C-ACT). And then the doctor will check and calculate the scores after completion.

Intervention type: DIAGNOSTIC_TEST
Intervention: The level of biomarkers in Peripheral blood
Description: All participants will be extracted 5ml peripheral blood into the anticoagulant tube by nurses and the peripheral blood will be detected for biomarkers of asthma. Children with asthma will take pulmonary function, blood test and specific IgE test etc. The lung function test will be performed by professional technicians and the results will be interpreted by specialists. The blood test and specific IgE test will be collected by specialist nurses and the results will be issued by professional inspectors. Children with asthma and their guardians will be asked for filling the questionnaire of Childhood Asthma Control Test (C-ACT). And then the doctor will check and calculate the scores after completion.
Study: NCT05474547

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation
Description: Students will meditate for 30 min every day for 10 days
Study: NCT04594733

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: minocycline (200 mg daily) and NAC (1200 mg daily) followed by placebo
Description: minocycline (200 mg daily) and NAC (1200 mg daily) followed by placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo followed by minocycline (200 mg daily) and NAC (1200 mg daily)
Description: Placebo followed by minocycline (200 mg daily) and NAC (1200 mg daily)
Study: NCT04319146

Intervention type: PROCEDURE
Group type: OTHER
Intervention: robot-assisted radical prostatectomy
Description: robot-assisted radical prostatectomy as first-line treatment
Study: NCT05560009

Intervention type: DRUG
Intervention: Fluorodopa F 18
Description: Given IV

Intervention type: PROCEDURE
Intervention: Magnetic Resonance Imaging
Description: Undergo PET/MRI

Intervention type: PROCEDURE
Intervention: Positron Emission Tomography
Description: Undergo PET/MRI

Intervention type: RADIATION
Intervention: Radiation Therapy
Description: Receive standard of care radiation therapy

Intervention type: PROCEDURE
Intervention: Surgical Procedure
Description: Undergo standard of care surgery
Study: NCT04970407

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Botulinum toxin type A
Description: Intramuscular Injection, concentration 300 units (U)

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Botulinum toxin type A
Description: Intramuscular Injection, concentration 50 U

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Botulinum toxin type A
Description: Intramuscular Injection, concentration 50 U
Study: NCT05786599

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: methadone
Description: The treatment arm will take methadone 2 mg PO q8h and a placebo called placeboD PO qdaily. PlaceboD and duloxetine will be placed in capsules to be virtually indistinguishable.~Participants will be followed (televisit or in-person) by assessors every week; this will take approximately 15 minutes. This includes review of questionnaire(s), adverse events (and any potential management), and recommendations on dose titration. To maintain blinding and ensure standardization across assessors, titration protocols will be provided. If pain is not controlled, the assessors will instruct the participant to increase their methadone/placeboM drug by 1 capsule PO q8h and their duloxetine/placeboD drug to 2 capsules PO qdaily (the study maximum). If there are poorly tolerated adverse events the dose will be reduced to the previously tolerated dose, and then the following week they may attempt to titrate up again per the above protocol.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: duloxetine
Description: The control arm will receive duloxetine 30 mg PO qdaily, and a placebo called placeboM PO q8h. PlaceboM and methadone will be placed in capsules to be virtually indistinguishable.~Participants will be followed (televisit or in-person) by assessors every week; this will take approximately 15 minutes. This includes review of questionnaire(s), adverse events (and any potential management), and recommendations on dose titration. To maintain blinding and ensure standardization across assessors, titration protocols will be provided. If pain is not controlled, the assessors will instruct the participant to increase their methadone/placeboM drug by 1 capsule PO q8h and their duloxetine/placeboD drug to 2 capsules PO qdaily (the study maximum). If there are poorly tolerated adverse events the dose will be reduced to the previously tolerated dose, and then the following week they may attempt to titrate up again per the above protocol.
Study: NCT04938596

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Respiratory bundle
Description: * Provision of N95 masks and strong recommendation of use to all household contacts and the index case when sharing a room together, for 2 weeks~* Recommendation to index case to sleep in a room alone, with the door closed and avoid sharing room with others during 2 weeks~* Promotion of strategies to improve house ventilation during 2 weeks~* Provision of a TB leaflet and nurse education about TB transmission.
Study: NCT06333483

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Obecabtagene autoleucel (obe-cel)
Description: Following lymphodepletion with chemotherapy (cyclophosphamide and fludarabine) patients will be treated with a single dose of obe-cel
Study: NCT05365334

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low intensity exercise session
Description: subjects will exercise at 30% maximal oxygen consumption (VO2max) for 45-60 minutes

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate intensity exercise session
Description: subjects will exercise at 65% maximal oxygen consumption (VO2max) for 30-45 minutes

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High intensity exercise session
Description: subjects will completed 10x1minute exercise intervals at maximal oxygen consumption (VO2max) with 1 minute active recovery between
Study: NCT05475834

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SIM0417
Description: Single oral dose of 750 mg SIM0417 coadministered with 100 mg ritonavir.
Study: NCT04163926

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intervention Group cataract follow up
Description: Intervention group will have cataract follow up conducted by the referring optometrist 4-6 weeks after surgery

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care consultant follow up
Description: Usual care group - Consultant led post op follow up
Study: NCT05911789

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Online adaptive radiation therapy
Description: A dose of 45Gy will be delivered to planning target volume (PTV)
Study: NCT06186596

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Triamcinolone delivered via injection assistance device
Description: 0.1mL of 1% to 2% triamcinolone solution will be delivered to up to 3 facial inflammatory acne lesions
Study: NCT05777083

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: KardiaMobile 6L
Description: Before coronary angiography, all participants will contact both fingers on the two probes at the front side of portable 6-leads electrocardiogram recorder (KardiaMobile 6L), and be recorded all six leads by contacting the other side of probe at lower extremities (left hip bone ridge, thigh, knee, lower abdomen, etc.).

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: KardiaMobile 6L
Description: Before coronary angiography, all participants will contact both fingers on the two probes at the front side of portable 6-leads electrocardiogram recorder (KardiaMobile 6L), and be recorded all six leads by contacting the other side of probe at lower extremities (left hip bone ridge, thigh, knee, lower abdomen, etc.).
Study: NCT05298436

Intervention type: OTHER
Intervention: Follow-up interview
Description: All participants will be followed up at defined time points post-stroke by face-to-face or telephone interview or postal questionnaire.

Intervention type: OTHER
Intervention: Follow-up interview
Description: All participants will be followed up at defined time points post-stroke by face-to-face or telephone interview or postal questionnaire.
Study: NCT05709405

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reading intervention
Description: The intervention will use a reading program called Lesing for alle (Reading for all) based on the research of Accessible Literacy Learning (ALL) which is an evidence-based approach, designed to teach reading skills to students with various intellectual disabilities, including autism spectrum disorders
Study: NCT06077435

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AI
Description: AI system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AI
Description: AI system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AI
Description: AI system
Study: NCT05172882

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wound site infiltration
Description: Block fluids that were prepared as 20 ml 0.25% bupivacaine before the intervention, will be applied through the upper and lower incision lips on the suprainguinal surgical site.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transversalis fascia plane block
Description: External, internal oblique, and transversus abdominis muscles will be visualized by the ultrasound device. After transversalis fascia will be seen, transversalis fascia plane block will be performed. As a block fluid 20 ml 0.25% bupivacaine will be applied.
Study: NCT05372679

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Renal denervation
Description: The TIVUS system will be used for renal denervation
Study: NCT05716529

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rehabilitation protocol
Description: It's a four phases rehabilitation protocol mainly based on the remodeling process of the graft., emphasizing full passive knee extension, immediate weight bearing as tolerated and functional exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: rehabilitation protocol
Description: It's a four phases rehabilitation protocol mainly based on the remodeling process of the graft., emphasizing full passive knee extension, immediate weight bearing as tolerated and functional exercises
Study: NCT04443959

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PUMAS
Description: Treatment consists of 6 weekly telemedicine sessions during pregnancy.
Study: NCT06485336

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin 40mg
Description: Each tablet will be taken once daily for 84 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Each tablet will be taken once daily for 84 days.
Study: NCT06171022

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cherry seed pillow
Description: 4 Weeks, 5 days a week, in addition to the routine physiotherapy application, 20 minutes of heated cherry seed pillow will be applied to the participant's back area.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: 4 Weeks, 5 days a week, in addition to the routine physiotherapy application, 20 minutes of hotpack will be applied to the participant's back area.
Study: NCT05015725

Intervention type: DIAGNOSTIC_TEST
Intervention: Quality of life assessment, biochemical measures
Description: Psychological tests: ThyDQol, ThySRQ and the Somatosensory Amplification Scale (SASS) adding up to \~50 items including demographic variables.~Recording of basic anthropometric data. Blood draw Laboratory tests: TSH, T3, FT3, FT4, aTPO, rT3, serum cholesterol, CK, GOT, GPT, creatinine and sodium levels.
Study: NCT04871347

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TWP-101
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TWP-101
Description: IV infusion
Study: NCT06151210

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5219
Description: 1 tablet/day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Stillen® Tab
Description: 3 tablets/day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DA-5219 Placebo
Description: 1 tablet/day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Stillen® Tab Placebo
Description: 3 tablets/day
Study: NCT06342479

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Discharge Education
Description: Discharge education will be provided.
Study: NCT04342013

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Clinical Decision Support Application
Description: Robust, real-time medication-related clinical decision support application for use in the operating room. The application is fully integrated with existing clinical systems. It provides visual alerts for medication errors and adverse medication events at the point-of-care.
Study: NCT05194241

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: One MORE
Description: One MORE is a 2-hour adaptation of the manualized MORE program and will be divided into four, 30-minute segments. In the first segment, participants will be introduced to mindfulness and guided though a body scan practice, which directs participants to systematically shift attention from one part of the body to the next. Mindful pain management will be the focus of the second segment and participants will be guided through a mindfulness of pain practice in which they will learn to deconstruct pain into sensory, emotional, cognitive, and behavioral components. The third segment will focus on managing the negative thoughts and emotion that can amplify pain with mindful reappraisal, and the fourth segment will focus on increasing the positive emotions that can attenuate pain with mindful savoring.
Study: NCT05834920

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial pulse stimulation (TPS)
Description: Participants will be treated with the TPS device NEUROLITH (Storz Medical AG). Treatments will be administered for up to 12 sessions within 4 weeks, each session consisting of 6000 TPS pulses of 0.2 mJ/mm².

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neurofeedback
Description: Participants will engage in a neurofeedback game designed to increase the ratio of theta/beta frequency bands in electroencephalography measurement. This intervention will be delivered for up to 12 sessions within 4 weeks.
Study: NCT05262855

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]FAPI-46
Description: \[68Ga\]-FAPI-46 is a radioactive diagnostic agent indicated for use with Positron Emission Tomography (PET) imaging for the detection of Fibroblast Activation Protein (FAP) positive cancer cells and cancer-associated fibroblasts (CAF) in patients with pancreatic ductal adenocarcinoma (PDAC).
Study: NCT06045494

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Meiji Yogurt Group
Description: Participants in this arm need to eat assigned product for 12 weeks, one bottle each day.
Study: NCT05171205

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Spinal cord stimulation (SCS) is a very thin electrode implanted in the dorsal epidural space of the spinal cord to improve the patient's symptoms by stimulating the spinal nerves with pulsed electrical currents, which attenuate or enhance the flow of nerve impulses from the periphery to the central system, i.e., stimulating thick fibers to achieve therapeutic results. SCS system consists of three components: an electrode implanted in the epidural space of the patient's spinal cord, a stimulator implanted subcutaneously in the abdomen or buttocks that delivers electrical impulses, and an extension cord that connects the two.
Study: NCT06391437

Intervention type: DIAGNOSTIC_TEST
Intervention: Extraction of blood sample
Description: Blood samples will be collected from all patients during the first 24 h of admission before enteral nutrition and/ or parenteral nutrition.

Intervention type: DIAGNOSTIC_TEST
Intervention: Extraction of blood sample
Description: Blood samples will be collected from all patients during the first 24 h of admission before enteral nutrition and/ or parenteral nutrition.
Study: NCT05643209

Intervention type: PROCEDURE
Group type: OTHER
Intervention: ablation
Description: epicardial substrate homogenization (ablating abnormal fragmented prolonged low-frequency ventricular electrograms) in consecutive patients undergoing catheter ablation
Study: NCT06174545

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pigment Solution Program
Description: adjuvant therapy for melasma that contains of combination formula consisting of morning cream - containing kojic acid, Vitamin E, Vitamin A and AquaxylTM complex; night cream - contains kojic acid, glycolic acid and AquaxylTM complex, scrub granules; and cleaning fluid containing vegetable oil and lactic acid.
Study: NCT06227065

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitomycin
Description: In PDOs from patients that show highest response to Mitomycin, this drug will be instilled intravesically once weekly for 6 times.~Mitomycin C will be used as 20mg dry powder. Prior to use, the powder will be dissolved in 50ml of 0.9% saline solution according to the manufacturer instructions

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: In PDOs from patients that show highest response to Gemcitabine, this drug will be instilled intravesically once weekly for 6 times.~Gemcitabine will be used as 2000 mg/50ml. For intravesical application, 1000mg of gemcitabine (corresponding to 25ml) will be diluted in 25ml 0.9% saline solution, to obtain the gemcitabine concentration of 1000mg/50ml used for instillation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: In PDOs from patients that show highest response to Docetaxel, this drug will be instilled intravesically once weekly for 6 times.~Docetaxel will be used as 140mg/7ml solution. For intravesical application, 48.825ml of saline will be added to 1.875ml Docetaxel solution (according 37.5mg of Docetaxel). The concentration of this solution is 0.74mg/ml by a total volume of the instillation solution of 50,7.