TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06155006

Intervention type: DIAGNOSTIC_TEST
Intervention: rapid diagnostic test HCV Ab Plus Rapid test
Description: The sample will be taken by trained personnel by capillary puncture of the thumb region of the fingers of the right hand, after asepsis and antisepsis, the rapid diagnostic test HCV Ab Plus Rapid test with INVIMA registration 2018RD-0002353-R1 will be used with operational characteristics that allow its performance at the point of care obtaining a result in 15 to 20 minutes. This rapid test for antibodies against HCV may be replaced by another test with similar operational characteristics (sensitivity and specificity).
Study: NCT06311955

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Carbon ion radiotherapy
Description: The patients will receive 72GyE per 18 fractions of carbon ion radiotherapy. Patients with thymus cancer should be combined with platinum-based regimen (including etoposide combined with cisplatin / carboplatin / loplatin / nedaplatin; paclitaxel combined with cisplatin or cisplatin / carboplatin / loplatin / nedaplatin; docetaxel combined with cisplatin / carboplatin / loplatin / nedaplatin) for at least 4 cycles. The primary endpoint was progression-free survival and toxicities, and the secondary endpoint was local relapse-free survival, overall survival and cause-specific survival.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: combined with platinum-based regimen
Description: combined with platinum-based regimen
Study: NCT05580263

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: aerobic exercise
Description: The main AE program will be designed and controlled for at least moderate intensity of heart rate reserve (HRR) lasting 30 minutes. The goal of intensity will be set at least 40% of HRR during the first two weeks, and then progressively increase the targeted intensity at the end of 16 weeks with 60% HRR. The motions will design by involving core muscle training (e.g., march, step touch, lunge, V-step, box step, twist, knee up, scoop, and scissors).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: aerobic exercise
Description: The main AE program will be designed and controlled for at least moderate intensity of heart rate reserve (HRR) lasting 30 minutes. The goal of intensity will be set at least 40% of HRR during the first two weeks, and then progressively increase the targeted intensity at the end of 16 weeks with 60% HRR. The motions will design by involving core muscle training (e.g., march, step touch, lunge, V-step, box step, twist, knee up, scoop, and scissors).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: resistance exercise
Description: In the process, the participants will be instructed by resisting the weight smoothly, and peaking at hold. RE prescription consist of 2-4 sets with 10-15 repetitions per set with a rest interval of 1-2 minutes between sets to improve muscular fitness.~The first two weeks will start with two sets of 10-15 repetitions and then gradually progress on four sets of 15 repetitions at the end of 16 weeks. The total duration of RE will lasting around 15 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: resistance exercise
Description: In the process, the participants will be instructed by resisting the weight smoothly, and peaking at hold. RE prescription consist of 2-4 sets with 10-15 repetitions per set with a rest interval of 1-2 minutes between sets to improve muscular fitness.~The first two weeks will start with two sets of 10-15 repetitions and then gradually progress on four sets of 15 repetitions at the end of 16 weeks. The total duration of RE will lasting around 15 minutes.
Study: NCT05887713

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental: Alpha-Stim 100
Description: Subjects in CES intervention group will run CES at home daily for 6 weeks. Study staff will call weekly to ensure adherence to CES treatment, gather CES usage data for the week and to answer any questions.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Comparator
Description: Subjects in CES sham group will run sham CES at home daily for 6 weeks. Study staff will call weekly to ensure adherence to sham CES treatment, gather sham CES usage data for the week and to answer any questions.
Study: NCT06408077

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NaCl-Administration
Description: Intravenous administration of NaCl 3% until an increase of plasma sodium of 5 to 8 mmol/l has been achieved
Study: NCT06014853

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOL-804-F
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOL-804-F
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOL-804-F
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOL-804-F
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zytiga
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zytiga
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zytiga
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zytiga
Description: All subjects who have been fasting for at least 10 hours prior to administration will take investigational products orally with water on the administration day of each period.
Study: NCT05291546

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGN9035
Description: Part A: Single dose administered by IV infusion on day 1. Part B: Selected doses administered by IV infusion on day 2 or 22.
Study: NCT04770324

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Interposition supraciliary implant
Description: Surgical placement of 2 interposition supraciliary implant in the supraciliary space
Study: NCT05326789

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: REBOA catheter
Description: balloon occlusion of the aorta during cardiac arrest to optimize coronary and cerebral perfusion.
Study: NCT04762238

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diacutaneous Fibrolysis
Description: Diacutaneous Fibrolysis is a non invasive physiotherapeutic technique applied by means of a set of metallic hooks ending a spatula with bevelled edges that help to treat the muscles and conjunctive tissues and trying to improve mobility between mobility between muscle planes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Diacutaneous Fibrolysis
Description: Diacutaneous Fibrolysis is a non invasive physiotherapeutic technique applied by means of a set of metallic hooks ending a spatula with bevelled edges that help to treat the muscles and conjunctive tissues and trying to improve mobility between mobility between muscle planes.
Study: NCT05538494

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BFR intervention
Description: Training is applied to this group using low-load exercises with restriction of blood flow. Based on the variables used by the major part of the protocols used in studies on the ERFS, the protocol that will be applied to this group will consist of the following parameters.~* Training: 1 series of 30 repetitions followed by 3 series of 15 repetitions of squats~* Rest between series: Duration of 45 seconds.~* Workload: 30% of 1RM.~* Cadence: 2 seconds for the concentric phase and 2 seconds for the eccentric phase (2:2).~* Cuff pressure: The inflation pressure will be individualized for each individual.~A pressure equivalent to 80% of the minimum pressure necessary for the total occlusion of the femoral artery.~• Cuff placement: proximal quadriceps.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High load intervention
Description: A program will be applied to this group of exercise with high loads as a method of treatment in which the following will be applied parameters:~* Training: 4 series of 12 repetitions of squats.~* Rest between series: Duration 2 minutes.~* Workload: 70% of 1RM.
Study: NCT05374642

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive training
Description: tablet-based cognitive training for 12 weeks, 30 minutes each time, at least 5 times a week

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: active control
Description: tablet-based cognitive training tasks with weak or no difficulty changes, 5 times a week, 30 minutes each time for 12 weeks
Study: NCT05443464

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OSSM-001
Description: Direct IV infusion of OSSM-001

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OSSM-001
Description: Direct IV infusion of OSSM-001

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OSSM-001
Description: Direct IV infusion of OSSM-001

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OSSM-001
Description: Direct IV infusion of OSSM-001
Study: NCT05658458

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vericiguat (Verquvo, BAY1021189)
Description: The recommended starting dose of vericiguat is 2.5 mg once daily, taken with food. The dose of vericiguat would be doubled approximately every 2 weeks to reach the target maintenance dose of 10 mg once daily, as tolerated by the participant.
Study: NCT05291546

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGN9035
Description: Part A: Single dose administered by IV infusion on day 1. Part B: Selected doses administered by IV infusion on day 2 or 22.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGN5381
Description: Part B: Selected doses administered by IV infusion on day 1.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Part A: Single dose administered by IV infusion on day1. Part B: Single dose administered by IV infusion on day 1, day 2 and/or day 22.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Part A: Single dose administered by IV infusion on day1. Part B: Single dose administered by IV infusion on day 1, day 2 and/or day 22.
Study: NCT05910203

Intervention type: OTHER
Group type: OTHER
Intervention: The effectiveness of education
Description: Training will be provided on smoking cessation.

Intervention type: OTHER
Group type: OTHER
Intervention: The effectiveness of education
Description: Training will be provided on smoking cessation.
Study: NCT05211674

Intervention type: OTHER
Intervention: quantified analysis of postural control during activities of daily living
Description: functional tests that reproduce tasks of daily living (timed up and go test with and without dual cognitive task, modified Glittre ADL test)

Intervention type: OTHER
Intervention: quantified analysis of postural control during activities of daily living
Description: functional tests that reproduce tasks of daily living (timed up and go test with and without dual cognitive task, modified Glittre ADL test)
Study: NCT06547333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM310
Description: CM310 Recombinant Humanized Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM310
Description: CM310 Recombinant Humanized Monoclonal Antibody Injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06406582

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Zirconia laminate veneer
Description: Zirconia veneers are milled with computer-aided manufacturing technology from multilayered zirconia discs with shade matched with adjacent teeth. After sintering, veneer surfaces are treated with a hydrofluoric acid-nitric acid mixture. Next, veneers are cut back if necessary to provide space for characterization. Veneers are bonded with a light-cured veneer adhesive system (Relyx Veneer LC, 3M, USA).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Lithium Disilicate laminate veneer
Description: Lithium Disilicate veneers are milled with computer-aided manufacturing technology from lithium disilicate blocks with shade matched with adjacent teeth. After sintering, veneer surfaces are treated with hydrofluoric acid. Next, veneers are cut back if necessary to provide space for characterization. Veneers are bonded with a light-cured veneer adhesive system (Relyx Veneer LC, 3M, USA).
Study: NCT05547919

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 18F-PSMA PET/CT
Description: Patients with metastasized gastrointestinal tumors, that exhibit histological PSMA expression, receive an additional 18F-PSMA PET/CT to routine imaging.
Study: NCT05117684

Intervention type: PROCEDURE
Intervention: Novel
Description: Balloon- Occlusion thrombolysis was done in adjunct to thrombus maceration, balloon sweeping and thrombosuction.

Intervention type: PROCEDURE
Intervention: Conventional
Description: Continuous catheter directed thrombolysis (Continuous urokinase infusion) was done along with thrombus maceration, balloon sweeping and thrombosuction.
Study: NCT06131983

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-DUX4 for Injection
Description: single or multiple doses of ARO-DUX4 by intravenous (IV) infusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: calculated volume to match active treatment by IV infusion
Study: NCT05199233

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Muse S™ Headband system
Description: Clinical grade, headband style, wireless EEG (electroencephalogram is a test used to evaluate the electrical activity in the brain) system and designed to interact with a mobile device (smartphone or tablet).
Study: NCT04644276

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mask with Mask Adhesive/Arm 1
Description: Patients will be randomized to Arm1 if they receive the mask adhesive and mask on the first study night then the mask without the mask adhesive on the second study night.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Mask without Mask Adhesive / Arm 2
Description: Patients will be randomized to Arm 2 if they receive the mask without mask adhesive on the first study night then the mask adhesive with the mask on the second study night.
Study: NCT04727450

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive training
Description: Involves participants engaging in selected games which require thinking skills to be played in a group of 2-4 people.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive training
Description: Involves participants engaging in selected games which require thinking skills to be played in a group of 2-4 people.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive training
Description: Involves participants engaging in selected games which require thinking skills to be played in a group of 2-4 people.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: physical training
Description: Involves learning of preselected routines of line dancing taught by a line dance instructor.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: physical training
Description: Involves learning of preselected routines of line dancing taught by a line dance instructor.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: physical training
Description: Involves learning of preselected routines of line dancing taught by a line dance instructor.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Combination of cognitive and physical training (CCPT)-BIGMAP
Description: BIGMAP is a program engaging participants in specially designed cognitive/memory games together with physical training (Fu \& Chow, 2019).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Combination of cognitive and physical training (CCPT)-BIGMAP
Description: BIGMAP is a program engaging participants in specially designed cognitive/memory games together with physical training (Fu \& Chow, 2019).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Combination of cognitive and physical training (CCPT)-BIGMAP
Description: BIGMAP is a program engaging participants in specially designed cognitive/memory games together with physical training (Fu \& Chow, 2019).
Study: NCT04736485

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: perioperative treatment
Description: FLOT + Spartalizumab
Study: NCT05869331

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Early mobilization
Description: Patients randomized to nonoperative treatment have already received treatment using early mobilization in the original trial, and all fractures have been confirmed healed. Mobilization consisted of 5 repetitions of full finger extension followed by maximum finger flexion, and 5 such sets of 5 were required per day for the first 6 weeks. Buddy taping or resting splint was offered if the patient experienced difficulty, and mobilization was performed by all patients in this treatment arm.
Study: NCT06373354

Intervention type: DEVICE
Intervention: Digital Breast Tomosynthesis (DBT)
Description: Undergo tomosynthesis imaging
Study: NCT05898581

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PENG Block
Description: Participants will receive a PENG block with local anesthetics (which is a freezing medication, in this case, 0.5% ropivacaine) before receiving spinal anesthesia.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Control Group
Description: Participants will receive a sham PENG block performed with 20ml of normal saline solution before spinal anesthesia. After, patients will receive ILAI (performed by the operating surgeon) with a plain solution of ropivacaine 0.25% 60ml.
Study: NCT06280638

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual stent-guided incremental optimization strategy (VIOS)
Description: PCI is performed according to strategy recommended by Imaging-Heart Team based on VIOS protocol.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard angiographic strategy
Description: PCI is performed based on international guidelines, local protocols and practice.
Study: NCT05869331

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Operative treatment
Description: Patients randomized to operative treatment have already received treatment using open reduction and internal fixation (ORIF) with cortical screws in the original trial, and all fractures have been confirmed healed. Surgery was performed under general anaesthesia through a dorsal incision centered over the fractured metacarpal. Reduction was performed under visual inspection and fixation performed using 2 or more cortical screws (Synthes Compact Hand 2.0) as first option. At the surgeons preference fixation using plate and screw fixation was also allowed. Postoperatively patients were put in a plaster cast for two weeks and then hand therapy was initiated.
Study: NCT06288854

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: weight gain each group
Description: weight gain after 12 Weeks
Study: NCT05540353

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transvaginal photobiomodulation
Description: Low light laser therapy applied transvaginally using a small vaginal wand with sterile disposable wand covers. The intervention last 3-5 minutes based on a surface area calculation performed at the beginning of the intervention, and involves a gentle in and out motion of the wand to deliver light energy to the muscles of the pelvic floor.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham therapy
Description: Use of the same vaginal wand as active arm, but without activation of the machine. The intervention last 3-5 minutes, and involves a gentle in and out motion of the wand to massage the muscles of the pelvic floor, without delivery of light therapy.
Study: NCT06093269

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood samples
Description: For all subjects (short kinetics):~* Pre-injection of cefazolin~* Start of next dialysis~* Two hours after start of subsequent dialysis~* End of next dialysis, before cefazolin administration~Only in hospitalized subjects (rich kinetics):~* 30 minutes, 1h and 2h after cefazolin injection, to describe the cefazolin peak and possible post-dialysis rebound~* 12h, 24h and 36h after cefazolin injection, to better describe cefazolin elimination and distribution
Study: NCT05944588

Intervention type: OTHER
Intervention: Pulmonary Ultrasound
Description: 2 pulmonary ultrasound exams, one before respiratory weaning test, and one other at the end of the respiratory weaning test, before extubation

Intervention type: OTHER
Intervention: Pulmonary Ultrasound
Description: 2 pulmonary ultrasound exams, one before respiratory weaning test, and one other at the end of the respiratory weaning test, before extubation
Study: NCT06280768

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2004 injection
Description: dose 1 or dose 2 or dose 3 or dose 4 or dose 5 or dose 6
Study: NCT05339841

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile health application
Description: The mHealth app delivers a personalized support program of digital health. Specifically, using ad hoc designed algorithms which uses the data self-reported by the subject and/or collected by the recruiter at baseline, the App delivers periodic messages with advice, motivational reminders and support to improve lifestyle habits and risk factor control.
Study: NCT06331039

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PFMT
Description: PFM exercises were done. Each session were 45 minutes, 2 days a week on a group basis with the physiotherapist, and 1 day a week as a home program, for 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PFMT+Otago
Description: It were done by combining Otago exercises and PFM exercises. Each session were 45 minutes, 2 days a week on a group basis with the physiotherapist, and 1 day a week as a home program, for 12 weeks.
Study: NCT06288854

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: weight gain each group
Description: weight gain after 12 Weeks
Study: NCT05911360

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DTG/3TC
Description: DTG/3TC FDC will be administered once daily.