TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06349824

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: injection Dextrose water
Description: dextrose will be injected around median nerve in wrist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: injection Dextrose water
Description: dextrose will be injected around median nerve in wrist

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: USG machine
Description: usg guided nerve hydrdissection

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: USG machine
Description: usg guided nerve hydrdissection

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: USG machine
Description: usg guided nerve hydrdissection
Study: NCT04880239

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Posterior colpoperineorrhaphy
Description: Patients having a sacralcolpopexy will be randomized to ultra lightweight mesh (Coloplast Restorelle) with posterior colpoperineorrhaphy or the same procedure without the posterior colpoperineorrhaphy
Study: NCT03110484

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed 500 MG
Description: Pemetrexed 500 mg/m2

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Erlotinib
Description: Erlotinib 100mg once daily
Study: NCT05638581

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: LTOWB
Description: Participants will receive Low Titer O Whole Blood administered intravenously or intraosseously.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Components
Description: Participants will receive separated blood components (i.e., units of red cells, plasma, platelets, and cryoprecipitate) co-administered intravenously or intraosseously.
Study: NCT06468566

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound light scattering imaging equipment
Description: Radiologists use ultrasound light scattering imaging to evaluate the benign and malignant nature of breast nodules

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound light scattering imaging equipment
Description: Radiologists use ultrasound light scattering imaging to evaluate the benign and malignant nature of breast nodules
Study: NCT05766293

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Fibroblast cell lines not subjected to shockwaves from extracorporeal shockwave device
Description: Fibroblast cell lines (n=10) without shockwave exposure
Study: NCT05806073

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Elective neck dissection
Description: patient underwent elective neck dissection(level I-III) as initial treatment, along with the excision of the primary tumor

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Therapeutic neck dissection
Description: patient underwent Therapeutic neck dissection(level I-V) as initial treatment, along with the excision of the primary tumor
Study: NCT05846971

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational materials on validated methylation assay
Description: Educational materials include overall information on the assay including what the test does, how to use the test and report, and performance metrics on the test.
Study: NCT05720273

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: palicalcitol
Description: This study does not interfere with the clinical medication of the researchers, and the usage and dosage of the drugs will be recorded according to the actual use. The recommended starting dose of palicalcitol may be based on body weight, baseline iPTH, or combined with prior medication. Dose adjustment should be determined according to pre-dialysis iPTH, Ca and P. iPTH levels should be maintained at 150-300pg/ml, while Ca and P levels should be closely monitored. If hypercalcemia occurs, the dose should be reduced or medication should be discontinued until these parameters return to normal; Subsequently, the dose of palicalcitol should be restarted at a lower dose. If PTH levels decrease as a result of treatment, the dose of medication may need to be reduced accordingly. The dose adjustment interval is 2-4 weeks, and the dose can be adjusted immediately for safety reasons.
Study: NCT04749277

Intervention type: OTHER
Intervention: CAD EYE® (Fujifilm, Europe, Gesellschaft mit beschränkter Haftung, Dusseldorf, Germany)
Description: Methods plan~Phase 1. Brief virtual chromoendoscopy training on the characterization of colorectal polyps (WLI, LCI and BLI)~Phase 2. CAD EYE® system applied during colonoscopy retrieval:~2.1. CAD EYE® system OFF: Virtual chromoendoscopy (BLI) - independently characterization of a suspected polyp in WLI and BLI by the first endoscopist and by the second endoscopist (iconographic record) 2.2. CAD EYE® system ON: Characterization mode (BLI): Characterization of a suspected polyp by CAD EYE® and respectively level of characterization (1 to 3) (iconographic record) Phase 3. Histopathological evaluation (pathologist with gastrointestinal expertise): Resection and recovery of a suspected polyp for anatomopathological characterization
Study: NCT05848180

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ankle proprioceptive training (APT)
Description: APT comprise of exercises including towel curls, uni-leg stance on foam with activity, writing alphabets on gym ball with toes, picking marbles with toes.~BT includes tendem walk, side leg raises, sit to stand, side walk, back leg raise

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Balance training (BT)
Description: Balance training exercises comprising of side walk, tandem walk, standing on one leg, walking with alternating arm raise up to 90 degrees

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Balance training (BT)
Description: Balance training exercises comprising of side walk, tandem walk, standing on one leg, walking with alternating arm raise up to 90 degrees
Study: NCT05289076

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy drug
Description: Different combinations of chemotherapies will be tested in combination with monoclonal antibodies in zebrafish embryos against inplanted patients livermetastatic tissues.
Study: NCT05508399

Intervention type: OTHER
Intervention: DNA panel and RNA Sequencing
Description: Interventions include collecting samples, DNA panel test and full transcriptome sequencing.~Before collecting samples, obtaining written informed consent from patient in advance.~1. Blood cell samples;~2. Paraffin sample of residual tumor tissue of biopsy;~3. Paraffin sample of residual tumor tissue and paracancer tissue after gastrectomy.
Study: NCT06219486

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: D-dimer
Description: The investigators will measure a D-dimer test on participants and randomize on informing the physician on the value.
Study: NCT05892146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prevention therapy
Description: Sacubitril/Valsartan (25/80) mg twice a day for 1 year

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rescue therapy
Description: Sacubitril/Valsartan (25/80) mg twice a day for 1 year
Study: NCT05991830

Intervention type: PROCEDURE
Intervention: General anesthesia
Description: Older adults during elective surgery under general anesthesia with propofol, frontal EEG will recorded and a baseline plasma sample will be taken
Study: NCT05355649

Intervention type: DEVICE
Group type: OTHER
Intervention: PREGNOLIA SYSTEM
Description: The Pregnolia System is composed of two products: an active device (Pregnolia Control Unit) and a single-use sterile probe (Pregnolia Probe).~The intended use of the Pregnolia System is to provide information about the mechanical properties of the uterine cervix by assessing the tissue stiffness through a proxy parameter (the closing pressure, denominated CSI, or Cervical Stiffness Index, in mbar). The Pregnolia System is intended to be used in conjunction with the information obtained from the clinical evaluation of the patient and in addition to other standard examinations.
Study: NCT05294939

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketone monoester
Description: Consumption of 800mg/kg body weight of ketone monoester, divided in two intakes. The mixture will be prepared with bicarbonate. In addition, every hour they should consume 90g of carbohydrates.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control product consumption
Description: Consumption of placebo product (carbohydrates) masked with citric, divided in two intakes. The mixture will be prepared with bicarbonate. In addition, 90g of carbohydrates should be consumed every hour.
Study: NCT05363488

Intervention type: DRUG
Intervention: Bosutinib
Description: Patients receiving bosutinib treatment
Study: NCT04794738

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554
Description: SHR8554 Injection; high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554
Description: SHR8554 Injection; low dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline Solution
Description: Saline Solution

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Morphine
Study: NCT06101368

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Phsical Activity
Description: Combined Aerobic and Resistance Training

Intervention type: DRUG
Group type: OTHER
Intervention: Medication
Description: The drug will maintain their usual activity level, foot care, diet, and blood glucose diary on a regular basis. Continue the prescribed medication
Study: NCT05865951

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Isometric Exercises
Description: Isometric (same length) strengthening exercises of the neck muscles will be performed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isotonic Exercises
Description: Isotonic strengthening exercises for the neck muscles will be performed.
Study: NCT04614844

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Simulation Intervention
Description: Participants randomized to the intervention arm will receive CRI:SIS as a three-hour simulation session.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants randomized to the control arm will participate in four shift data collections, with no additional intervention.
Study: NCT05221008

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508；Placebo
Description: Group A:SHR6508 low dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508；Placebo
Description: Group B:SHR6508 medium dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508；Placebo
Description: Group C:SHR6508 high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508；Placebo
Description: Group D:SHR6508 high dose(single dose)
Study: NCT05370794

Intervention type: DRUG
Intervention: rhCG= Ovitrelle®, 250g/0.5ml = 26000IU/ml, Merck-Serono
Description: recombinant hCG

Intervention type: DRUG
Intervention: rFSH = Gonal F®, 300IU/0.5ml, Merck-Serono
Description: recombinant FSH
Study: NCT05760235

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic sleeve gastroplasty (ESG)
Description: ESG will be performed under general anaesthesia with orotracheal intubation. The Endomina® suturing system (EndoTools Therapeutics S.A., Gosselies, Belgium) mounted on a single channel endoscope will be used. This system allows to obtain full thickness gastric sutures through the gastric wall of the gastric body, leaving the antrum and the gastric fundus free15. The procedure will be performed with the patient in supine position. Carbon dioxide will be blown to stretch the gastric lumen. An initial endoscopic evaluation will be performed immediately to confirm the absence of any contraindication to ESG before suturing. The ESG starts with the reduction of the gastric body, suturing from distal to proximal and starting from the notch of the angulus and ending at the level of the fundus. 4-8 full thickness stitches will be placed, with 2 passes per stitch.
Study: NCT05484843

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: telenursing training based on self-care theory
Description: * A training guide based on the self-care theory specific to individuals diagnosed with stroke was prepared.~* Identification of the study/control group (randomization)~* Patients were informed and consents were obtained.~* Sample suitability was evaluated in line with the cognitive levels and inclusion criteria of patients diagnosed with stroke.~* All patients included in the sample group were pre-tested before discharge.~* Training was offered for the study group patients in line with the guide prepared based on self-care theory.~* Tele-nursing training was applied to the study group patients.~* Control group patients were followed up~* Post-tests were administered at the end of the 12-week period~* The training of the control group patients was completed~* Your data has been evaluated

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: telenursing training based on self-care theory
Description: * A training guide based on the self-care theory specific to individuals diagnosed with stroke was prepared.~* Identification of the study/control group (randomization)~* Patients were informed and consents were obtained.~* Sample suitability was evaluated in line with the cognitive levels and inclusion criteria of patients diagnosed with stroke.~* All patients included in the sample group were pre-tested before discharge.~* Training was offered for the study group patients in line with the guide prepared based on self-care theory.~* Tele-nursing training was applied to the study group patients.~* Control group patients were followed up~* Post-tests were administered at the end of the 12-week period~* The training of the control group patients was completed~* Your data has been evaluated

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: just observation
Description: For 3 months, patients were observed without intervention. The standard discharge training of the clinic was given.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: just observation
Description: For 3 months, patients were observed without intervention. The standard discharge training of the clinic was given.
Study: NCT05386082

Intervention type: OTHER
Intervention: Modified Delphi process
Description: The study involves a brief demographics survey and Delphi process, i.e. three rounds of information and surveys, in which participants will be asked to score/rank potential metrics.
Study: NCT06483542

Intervention type: OTHER
Intervention: bioenergetic balance
Description: Bioenergetic balance is calculated for all patients who had a resting energy expenditure measurement with indirect calorimetry.
Study: NCT05832528

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-FODMAP diet
Description: 6-week Low-FODMAP diet in patients with functional dyspepsia
Study: NCT05174117

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: single irradiation
Description: 46-48h irradiation after photosensitizer injection: power density: 200mW·cm-2, irradiation time: 900s, volume density: 180 J·cm-2

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Double irradiation
Description: 46-48h, 72h after photosensitizer injection, divided into two irradiation times: power density: 200mW·cm-2, irradiation time: 900s, volume density: 180 J·cm-2;Power density: 200mW·cm-2, irradiation time: 300s, volume density: 60 J·cm-2.
Study: NCT06487780

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle-focused Occupational Therapy Intervention
Description: The proposed intervention, led by trained occupational therapists, will focus on establishing sustainable self-care routines. It will consist of approximately 12 biweekly sessions, each lasting about an hour on average. Therapists will customize session timing and duration based on participant needs.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: Participants in the education group will receive standardized education materials on diabetic foot ulcers (DFUs), foot care, and offloading treatment to prevent foot ulcer recurrence.
Study: NCT06000592

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digitimer
Description: transcutaneous spinal cord stimulation for blood pressure control following spinal cord injury.
Study: NCT05118113

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Collection of mobilized hematopoietic stem cells (apheresis products) from healthy volunteers
Description: Mobilisation of hematopoietic stem cells by injection of filgrastim (authorized auxiliary medicinal product) for 4 consecutive days and leukapheresis on Day 5
Study: NCT05480176

Intervention type: OTHER
Intervention: Comprehensive intervention and management Ⅰ
Description: Mainly health advisory.

Intervention type: OTHER
Intervention: Comprehensive intervention and management Ⅱ
Description: Health advisory and regular follow-ups.

Intervention type: OTHER
Intervention: Comprehensive intervention and management Ⅲ
Description: Pharmaceutical and non-pharmaceutical (e.g. health advisory, rehabilitation, etc.) interventions according to standardized clinical guidelines, with regular follow-ups.
Study: NCT06079931

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Babaodan Capsule
Description: The patient received 66-66Gy/30-33F radiation therapy. During radiation therapy, concurrent chemotherapy includes receiving 45mg/m2 paclitaxel and carboplatin (AUC 2) once a week; From the start of radiation therapy to 2 months after the completion of CCRT, the patient takes 2 capsules of Babaodan orally every day, tid (1.8 g/day), and systemic corticosteroids can be used for acute radiation pneumonia patients with G ≥ 2.
Study: NCT05068986

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Asthma education
Description: All the study participants were subjected to an educational asthma program for 3 months for providing parents and children with information and skills to manage their asthma ,which was presented from the the first session, through providing a written asthma action plan, information about avoiding triggers, training in the correct use of medicines, including inhaler technique, information and support to maximize adherence . All patients were followed up by a phone call every 2 weeks and follow up visit monthly to confirm compliance to the educational program
Study: NCT04748939

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: recombinant subunit herpes zoster vaccine
Description: vaccine administration

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: recombinant subunit herpes zoster vaccine
Description: vaccine administration
Study: NCT04531592

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Valproic acid
Description: Valproate sodium in 5-ml single-dose vials containing 100 mg/ml of VPA. The appropriate dose of 140 mg/kg, based on the subject's weight at study entry, will be diluted in isotonic saline solution to a final volume of 300 ml for administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Isotonic saline solution
Description: Isotonic saline solution consisting of 0.9% sodium chloride in the volume of 300 ml for administration
Study: NCT05293548

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant COVID-19 Vaccine (CHO cell，NVSI-06-09)
Description: Intramuscular injection of Recombinant COVID-19 Vaccine (CHO cell，NVSI-06-09) in the deltoid muscle of the upper arm

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Inactivated COVID-19 vaccine (Vero cells)
Description: Biological/Vaccine: Inactivated COVID-19 vaccine (Vero cells) Intramuscular injection of Inactivated COVID-19 vaccine (Vero cells) in the deltoid muscle of the upper arm
Study: NCT06301308

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Intraurethral lidocaine gel alone
Description: participants received 10 ml of intraurethral lidocaine gel at a concentration of 2%

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraurethral lidocaine gel + lidocaine 2% injection
Description: participants received 10 ml of intraurethral lidocaine gel at a concentration of 2% and using the injection of lidocaine 2% to irrigate the urethra using a 20 ml syringe.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intraurethral lidocaine gel + liquid paraffinl
Description: Liquid paraffin were used to lubricate hte cystoscopy tube AND participants received 10 ml of intraurethral lidocaine gel at a concentration of 2%
Study: NCT05680493

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Manual pressure release
Description: lengthens the muscle up to the increasing resistance, then gradually applies gentle pressure on MTrp until fingers feels a definite increase in tissue resistance (first barrier). Pressure would maintain until clinician sense relief of tension

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dry needling
Description: A filiform needle is inserted at 45 degree in to trigger point and then twirl the needle up and down to release trigger point

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Heat therapy
Description: Hydro collator pack will be placed on affected area for relaxation and pain relief for 15 min

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Heat therapy
Description: Hydro collator pack will be placed on affected area for relaxation and pain relief for 15 min
Study: NCT06031298

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dentin Graft
Description: Dentin graft is a grafting technique of autogenous origin that uses the teeth extracted from the patient for the graft material preparation.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Dentin Graft
Description: Dentin graft is a grafting technique of autogenous origin that uses the teeth extracted from the patient for the graft material preparation.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Dentin Graft
Description: Dentin graft is a grafting technique of autogenous origin that uses the teeth extracted from the patient for the graft material preparation.
Study: NCT05576480

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Short-course radiotherapy
Description: 5×5Gy in Week 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Penpulimab
Description: Apply once in the first week, then every 3 weeks from the third week for four cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAPEOX
Description: Apply every 3 weeks from week 3 for 4 cycles

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TME surgery
Description: Patient will receive radical rectal cancer surgery
Study: NCT06236230

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: levodopa/carbidopa/entacapone
Description: On Day 1, subjects will be treated with levodopa/carbidopa/entacapone. Based on previous regimen. The dosage of levodopa/carbidopa/entacapone will be equal to the previous total daily dose of LD, and the frequency of administration of levodopa/carbidopa/entacapone is three or four times a day.~Levodopa/carbidopa/entacapone could be titrated in next 2 weeks according to the investigator's judgment, based on individual clinical response and tolerability.~After 2-week titration, the dose of levodopa/carbidopa/entacapone will remain as constant as possible to the end of study.