TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06379308

Intervention type: OTHER
Intervention: questionaries
Description: Questionaries will be administered :~* Anterior Cruciate Ligament Return to Sport and Injury (ACL-RSI)~* Tegner Activity Scale (TAS)~* Simple Knee Value (SKV)~* International Knee Documentation Commitee (IKDC)

Intervention type: OTHER
Intervention: datas of medical record
Description: datas of medical record will be collected : epidemiological data, morphological data, operative data, clinical and functional outcomes, and surgical complication.
Study: NCT05987566

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Morning meal challenge
Description: A Western-style diet meal which will be individualized for caloric consumption by estimated total daily energy expenditure eaten after 1 hour of waking up in the morning

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evening meal challenge
Description: A Western-style diet meal which will be individualized for caloric consumption by estimated total daily energy expenditure eaten within 1 hour of going to bed
Study: NCT05933486

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tongluo-Kaibi tablet plus placebo of pregabalin
Description: Tongluo-Kaibi Tablet 0.93g qd； Placebo of pregabalin 150mg qd. If the patient can tolerate it, it will be increased to 150mg bid one week later. If the patient cannot tolerate it, it will be maintained at 150mg qd until the 8th week.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: placebo of Tongluo-Kaibi tablet plus pregabalin
Description: placebo of Tongluo-Kaibi Tablet 0.93g qd； Pregabalin 150mg qd. If the patient can tolerate it, it will be increased to 150mg bid one week later. If the patient cannot tolerate it, it will be maintained at 150mg qd until the 8th week.
Study: NCT05547282

Intervention type: RADIATION
Group type: OTHER
Intervention: At the same time, the original regimen of immunomaintenance therapy was continued, according to the frequency of the original immunization regimen once every 3 weeks until progress.
Description: At the same time, the original regimen of immunomaintenance therapy was continued, according to the frequency of the original immunization regimen once every 3 weeks until progress.
Study: NCT05785572

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: supraescapular nerve radiofrequency
Description: supraescapular nerve radiofrequency or interescalenic braquial plexus for pain control in shoulder arthroplasty surgery

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: interescalenic braquial plexus
Description: supraescapular nerve radiofrequency or interescalenic braquial plexus for pain control in shoulder arthroplasty surgery
Study: NCT05919290

Intervention type: OTHER
Group type: OTHER
Intervention: MRI
Description: Non-invasive imaging technique that is used to take pictures of organs within the body.

Intervention type: OTHER
Group type: OTHER
Intervention: MRI
Description: Non-invasive imaging technique that is used to take pictures of organs within the body.
Study: NCT05909930

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic resistance exercise
Description: Therapeutic exercise program based on individualized progressive resistance exercises performed during 6 months at home, with a frequency of 1-3 sessions per week at the hospital.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: Education applied during all the therapeutic process, focusing on diverting the patient's attention away from the structural lesion, explaining the relationship between pain/disability and tissue injury, explaining the meaning of pain during exercises, and explaining the objectives of the implemented treatments.
Study: NCT06474910

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Connective tissue massage
Description: In addition to the exercise program for hand rehabilitation, 15 patients in this group will receive connective tissue massage of the hand and forearm area. The exercise program will include stretching exercises for the hand, strengthening exercises, normal joint movement exercises, functional exercises and tendon sliding exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Only exercise program will be applied to 15 patients in this group. The exercise program will include stretching exercises for the hand, strengthening exercises, normal joint movement exercises, functional exercises and tendon sliding exercises.
Study: NCT05303870

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Improving access to psychological therapies (IAPT)
Description: IAPT services provide evidence-based treatments for people with depression and anxiety disorders, and comorbid long-term physical health conditions or medically unexplained symptoms. IAPT services are characterised by three key principles:~1. Evidence-Based psychological therapies at the appropriate dose: NICE recommended therapies matched to the mental health problem, at the intensity and duration designed to optimise outcomes.~2. Appropriately trained and supervised workforce.~3. Routine outcome monitoring.
Study: NCT06003192

Intervention type: OTHER
Group type: OTHER
Intervention: Universal Opt-out HIV Screening
Description: Using a tablet device, offering universal opt-out HIV screening to adolescents seeking care in a pediatric emergency department.
Study: NCT05874323

Intervention type: GENETIC
Group type: OTHER
Intervention: Detection of RAGE gene polymorphism (rs1800625)
Description: Detection of RAGE gene polymorphism (rs1800625) By Molecular analysis (real time PCR)

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Detection of RAGE gene polymorphism (rs1800625)
Description: Detection of RAGE gene polymorphism (rs1800625) By Molecular analysis (real time PCR)
Study: NCT05320250

Intervention type: OTHER
Intervention: Single saliva collection
Description: 1 ml of saliva will be collected with Salivette swabs.

Intervention type: OTHER
Intervention: Single saliva collection
Description: 1 ml of saliva will be collected with Salivette swabs.

Intervention type: OTHER
Intervention: Single saliva collection
Description: 1 ml of saliva will be collected with Salivette swabs.
Study: NCT05353270

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yoga
Description: Yoga sessions will be completed 5 times per week for 4 weeks.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Waitlist control
Description: Waitlisted participants will maintain their normal exercise and diet for 4 weeks. After follow up testing at week 4, participants will be rerandomized to the yoga condition.
Study: NCT05320250

Intervention type: OTHER
Intervention: Saliva collection, longitudinal
Description: 1 ml of saliva will be collected with Salivette swabs. Subjects diagnosed with PD will undergo assessments and saliva sampling before starting rehabilitation treatment (T0), at the end of treatment (T1) and 3 months after the end of treatment (T2).
Study: NCT05540574

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zolpidem
Description: 5mg (and up to10mg) Diphenhydramine given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zolpidem
Description: 5mg (and up to10mg) Diphenhydramine given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching Placebo given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching Placebo given orally
Study: NCT05993559

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Arm I (No PMRT)
Description: The purpose of this study is to confirm that in patients with breast cancer who have undergone mastectomy after prior neoadjuvant chemotherapy, omitting radiotherapy is non-inferior to post-mastectomy radiotherapy (PMRT) in terms of 5-year disease-free survival (DFS) in patients with pathologic complete remission and a good response to treatment corresponding to RCB class 0-I, compared to patients treated with PMRT.

Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Arm II (PMRT)
Description: The purpose of this study is to confirm that in patients with breast cancer who have undergone mastectomy after prior neoadjuvant chemotherapy, omitting radiotherapy is non-inferior to post-mastectomy radiotherapy (PMRT) in terms of 5-year disease-free survival (DFS) in patients with pathologic complete remission and a good response to treatment corresponding to RCB class 0-I, compared to patients treated with PMRT.
Study: NCT06046625

Intervention type: OTHER
Intervention: Regular care with additional administration of a semi-structured interview
Description: Patients receiving regular care. In addition, a semi-structured interview is conducted.~The semi-structured interviews take place once after completion of the care pathway (after all appointments for check-ups associated with the treatment). The interview contains questions about the experience of patients with the care, the needs in this care, the experiences with the information received, the support/guidance, the turnaround time, the treatment received and areas for improvement.
Study: NCT05221723

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Exercise Training Group
Description: Participants will participate in a maximum of twice weekly exercise classes (90 minutes each class) for a total of 6 months. While participants will be encouraged to attend as many classes as able, there is no minimum requirement for class attendance. During the exercise classes, participants will participate in a 10-minute warm up, followed by 30-60 minutes of aerobic, resistance and/or balance training up to a maximum intensity of 8/10 on the rating of perceived exertion scale. Participants will finish each class with a 10-minute cool-down consisting of lower intensity exercise.
Study: NCT05309551

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IMT- Intervention group
Description: The resistive load will be readjusted weekly to reach 50% of maximal inspiratory pressure (MIP).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: IMT- Placebo group
Description: The inspiratory resistive load will be adjusted to the minimum value of the device (9 cm H2O) during all inspiratory muscle training sessions.
Study: NCT04961853

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Ultrasound and MRI
Description: Ultrasound examination and magnetic resonance imaging on the hand
Study: NCT04697810

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Namodenoson
Description: 25 mg q12hours x 36 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching capsules q12hours x 36 weeks
Study: NCT05861687

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esomeprazole
Description: Administered once a day per-oral (PO) with the dose of 0.4 mg/kg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lansoprazole
Description: Administered once a day per-oral (PO) with the dose of 15 mg if individual's body mass was \<30 kg, and 30 mg if it was \>30 kg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin
Description: Administered thrice a day per-oral (PO) with the dose of 25 mg/kg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: Administered thrice a day per-oral (PO) with the dose of 25 mg/kg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clarithromycin
Description: Administered twice a day per-oral with the dose of 7.5 mg/kg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clarithromycin
Description: Administered twice a day per-oral with the dose of 7.5 mg/kg
Study: NCT05895162

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JUVIA zinc containing vaginal gel treatment
Description: Women receive a single oral dose of fluconazole (150mg) followed by treatment with JUVIA zinc containing vaginal gel (daily for 2 weeks and twice per week thereafter).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluconazole 150Mg Tab
Description: Women receive oral fluconazole treatment with a single dose of oral fluconazole (150 mg).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluconazole 150Mg Tab
Description: Women receive oral fluconazole treatment with a single dose of oral fluconazole (150 mg).
Study: NCT06363279

Intervention type: OTHER
Group type: OTHER
Intervention: Conducting questionnaires
Description: The questionnaires will be administered online or in person.
Study: NCT04649268

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Group B
Description: The C2 CARE C2 Physio 2019.2 has been developed for physiotherapy rehabilitation purposes including vestibular disorders. Virtual reality environments will be provided via the VR Oculus Quest headset as part of the OKS exposure incorporated within a customised VRT programme. Participants will attend 45 minute individualised supervised sessions once weekly for 8 weeks. Participants in this rehabilitation group will also have a home-based exercise programme to practise on days not attending clinic. The home-based programme will incorporate customised VRT exercises with exposure to VR environments using the VR Oculus Quest headset.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group A
Description: Optokinetic stimulation treatment delivered through visual motion DVDs. Individualised 45 minute supervised sessions will occur for this group also once weekly for 8 weeks together with a home-based customised VRT programme incorporation the DVD to practise on days not attending clinic. Participants will have to use the OKS DVD for their exercises at home daily for 8 weeks as part of the prescribed home exercise programme.
Study: NCT05384379

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inhaled BZ371B
Description: Intubated patients suffering from ARDS will receive BZ371B in a dose of 12 mg. This will be divided into 2 nebulizations, each with 10 ml. The first nebulization is at a dose of 3 mg and the second at a dose of 9 mg.
Study: NCT05206591

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Secukinumab
Description: Secukinumab 300 s.c.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06494007

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sodium chloride
Description: The Diltiazem monotherapy group received 6.66 mL of IV sodium chloride 0.9% (NaCl) prior to receiving IV weight-adjusted diltiazem.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 90 mg of calcium
Description: The Diltiazem with 90 mg calcium group received 3.33 mL of IV calcium chloride (CaCl2, 90 mg) and 3.33 mL of IV NaCl 0.9% as pretreatment over 5-10 min prior to receiving IV diltiazem.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 180 mg Calcium
Description: The Diltiazem with 180 mg calcium group received 6.66 mL of IV CaCl2 (180 mg) as pretreatment prior to receiving IV diltiazem.
Study: NCT06138964

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: siSPARC + siLR4A microneedle patches
Description: siSPARC + siLR4A microneedle patch

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: siSPARC microneedle patch
Description: siSPARC microneedle patch
Study: NCT04710953

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous positive airway pressure machine
Description: CPAP device set at 6-8cmH2O for several hours
Study: NCT05335226

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combined haploidentical and umbilical cord blood allogeneic stem cell transplantation
Description: Patients will receive umbilical cord blood allogeneic stem cell transplantation at the same day as the haploidentical stem cell transplantation. (HLA 6-10/10, TNC≥1-3×10-7/Kg)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: haploidentical hematopoietic stem cell transplantation
Description: Receive haploidentical hematopoietic stem cell transplantation (HLA 6-10/10)
Study: NCT05987553

Intervention type: OTHER
Intervention: e-learning program
Description: All participants participate in this intervention: an e-learning program about the recognition of actinic keratosis. The program exists of 30 cases. Each case exists of a question and thorough explanation including references to various sources.
Study: NCT05342181

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Static exercises
Description: Participants will be treated with static core muscle exercises that are traditional group of exercises :~1. supine bridge~2. plank~3. oblique crunch~4. side lying with Abduction~This program includes static exercises performed thrice a week for 4 weeks.This exercise comprises 5 minutes warm up and slight stretching.Rest time of 2-3 minutes with proper stretching in between sets of activity. Subjects will be requested to undertake cool down exercises, which include aerobic workouts followed by stretching exercises, at the end of each day's exercise programme. Before beginning the next session's training, the subjects will be asked if they had any discomfort.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamic exercises
Description: Participants will be treated with dynamic core muscle exercises that were swiss ball exercises~1. bridging~2. straight leg raise in prone lying~3. straight leg raise with hand raise in prone lying~4. pelvic tilts~This program includes static exercises performed thrice a week for 4 weeks.This exercise comprises 5 minutes warm up and slight stretching.Rest time of 2-3 minutes with proper stretching in between sets of activity. Subjects will be requested to undertake cool down exercises, which include aerobic workouts followed by stretching exercises, at the end of each day's exercise programme. Before beginning the next session's training, the subjects will be asked if they had any discomfort.
Study: NCT04665336

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Circadian Timing Program
Description: Sleep hygiene training will be provided to the participants. They will be asked to make lifestyle changes according to the Circadian Timing Program created by the researcher.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Hygiene Training
Description: Sleep hygiene training will be given by the researcher. There will also be sleep hygiene training sections on the website.
Study: NCT04866888

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: closure of the uterine wall defect
Description: Uterine exteriorization followed by pealing of amniotic membranes to reach an accessible pole of the placenta to detect a plan of cleavage behind it. The independent hand of the surgeon passed through the previous plan from points of least resistance to high resistance. The defect will be repaired from the inner aspect of the uterus via running sutures using Vicryl (1-0) on a round needle, 45mm. the suture will pass from one edge to hitch the bed and pass to the other edge till we completely close the defect subsequently, controlling the bleeding. Uterine scar closure by running sutures in two layers, where the first layer compresses the placental bed defect externally.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ultrasound
Description: Before the procedure transabdominal and transvaginal ultrasound will be done to diagnose PAS and to map the uterine wall defects.~After 3 months,Transabdominal and transvaginal ultrasound with different modalities to assess the uterine wall, the cavity, endometrium, myometrium and the cervix. Isthmocele will be defined as a defect at uterine wall where residual myometrium thickness and ratio between residual myometrium and total myometrium thickness will be measured and recorded. The shape of the isthmocele will be also recorded.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: outpatient hysteroscopy
Description: Office hysteroscope will be done after patient consent to evaluate the uterine cavity if the patient is symptomatic or with abnormal sonography. It will be performed in the proliferative phase of the menstrual cycle. Non-steroidal anti-inflammatory will be given one hour before the procedure, then the patient will be in lithotomy position. Following aseptic rules, the rigid 4 mm hysteroscope will be inserted into the uterus through the cervix without using speculum nor tenaculum. Any pathology will be identified, and data will be recorded.
Study: NCT06104644

Intervention type: DRUG
Intervention: Deucravacitinib
Description: Non-interventional observational study of patients receiving treatment with commercially available deucravacitinib 6 mg once daily according to the Summary of Product Characteristics
Study: NCT05511493

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: fractional Erbium-YAG laser
Description: Platelet-rich plasma with fractional Erbium-YAG laser in localized stable vitiligo

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: microneedling
Description: Platelet-rich plasma with microneedling in localized stable vitiligo
Study: NCT04711148

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: orelabrutinib
Description: Orelabrutinib is a white, round, uncoated tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: orelabrutinib
Description: Orelabrutinib is a white, round, uncoated tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: orelabrutinib
Description: Orelabrutinib is a white, round, uncoated tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: orelabrutinib
Description: Orelabrutinib is a white, round, uncoated tablet
Study: NCT05597865

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Economic Empowerment Intervention
Description: Economic Empowerment Intervention comprising Financial Literacy Sessions and Youth Development Accounts

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Alcohol and Drug Use Risk Reduction Sessions
Description: All participants in the control and treatment arm will receive Alcohol and Drug Use Risk Reduction sessions tailored for Adolescents and Youths Living with HIV.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol and Drug Use Risk Reduction Sessions
Description: All participants in the control and treatment arm will receive Alcohol and Drug Use Risk Reduction sessions tailored for Adolescents and Youths Living with HIV.
Study: NCT05010850

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Colovac
Description: A removable, temporary intraluminal bypass device designed to safely postpone the creation of a protective stoma until 10 days after surgery for only patients who need it (do not have a healed anastomosis)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Stoma Creation
Description: Protective ileostomy
Study: NCT05071495

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartphone application
Description: Smartphone application named Signal, which connects patients and health providers