TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04823468

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Abbott®Ensure
Description: Abbott®Ensure: 55.8 g each time, three times a day, from the beginning to the end of radiotherapy

Intervention type: RADIATION
Group type: OTHER
Intervention: Intensity Modulated Radiation Therapy
Description: The prescribed dose was 68-76 Gy to Planning target volume of the primary tumor (PTVnx), 66-70 Gy to Planning target volume of the cervical lymph node (PTVnd), 60-64 Gy to planning target volume 1 (PTV1), and 50-54 Gy to planning target volume 2 (PTV2) in 30-33 fractions. The details of dose limits for organs at risk were based on the study 0225 from The Radiation Therapy Oncology Group (RTOG 0225).

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity Modulated Radiation Therapy
Description: The prescribed dose was 68-76 Gy to Planning target volume of the primary tumor (PTVnx), 66-70 Gy to Planning target volume of the cervical lymph node (PTVnd), 60-64 Gy to planning target volume 1 (PTV1), and 50-54 Gy to planning target volume 2 (PTV2) in 30-33 fractions. The details of dose limits for organs at risk were based on the study 0225 from The Radiation Therapy Oncology Group (RTOG 0225).

Intervention type: DRUG
Group type: OTHER
Intervention: cisplatin
Description: 80-100 mg/m² cisplatin given intravenously every 3 weeks concurrently with radiotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cisplatin
Description: 80-100 mg/m² cisplatin given intravenously every 3 weeks concurrently with radiotherapy.
Study: NCT04953442

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fit 24
Description: This 12-week goal-setting intervention will test the feasibility of using a Fitbit watch and motivational text messaging to improve physical activity and sleep in Hispanic youth (14-16 years of age) with obesity. Youth will be prompted to set weekly steps per day and hours of sleep per night goals. Text messages will be grounded in the Self-Determination Theory and will provide evidence-based strategies, support, and motivation to encourage youth to meet their goals.
Study: NCT05940181

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: XH001+ sintilimab
Description: During treatment period, subjects will receive 6 cycles of XH001+ sintilimab, followed by sintilimab monotherapy (sintilimab will be administered for up to 18 cycles or for 1 year, whichever comes first).
Study: NCT06010017

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STEPP Intervention
Description: Peer support intervention comprised of five learning modules on psychoeducation and supportive psychotherapy strategies, via virtual platform. If participants do not have a smart device, one will be provided by the study team.
Study: NCT05907369

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active EC training
Description: The active EC includes pairing contamination-related pictures (CSs) with pleasant pictures (USs). The EC training takes about 15 minutes and is administered for ten sessions (5 days a week) in 4 difficulty levels.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sham EC training
Description: The active EC includes pairing contamination-related pictures (CSs) with neutral pictures (USs). The EC training takes about 15 minutes and is administered for ten sessions (5 days a week) in 4 difficulty levels, the same as active EC training.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham EC training
Description: The active EC includes pairing contamination-related pictures (CSs) with neutral pictures (USs). The EC training takes about 15 minutes and is administered for ten sessions (5 days a week) in 4 difficulty levels, the same as active EC training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active tDCS
Description: For the active tDCS, the cathode is placed over the left OFC and the anode over the right cerebellum. The brain stimulation is delivered with a 2mA current intensity for 20 minutes in 10 sessions (5 days a week).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active tDCS
Description: For the active tDCS, the cathode is placed over the left OFC and the anode over the right cerebellum. The brain stimulation is delivered with a 2mA current intensity for 20 minutes in 10 sessions (5 days a week).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sham tDCS
Description: For the sham tDCS, the cathode is placed over the left OFC and the anode over the right cerebellum, the same as active tDCS. The device is on for 20 minutes, but the current intensity is under the threshold of affecting cortical activity modulation. The participants receive the sham tDCS in 10 sessions (5 days a week).

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham tDCS
Description: For the sham tDCS, the cathode is placed over the left OFC and the anode over the right cerebellum, the same as active tDCS. The device is on for 20 minutes, but the current intensity is under the threshold of affecting cortical activity modulation. The participants receive the sham tDCS in 10 sessions (5 days a week).
Study: NCT06331221

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle fatigue Protocol
Description: Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle fatigue Protocol
Description: Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle fatigue Protocol
Description: Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle fatigue Protocol
Description: Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.
Study: NCT05059691

Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Review of medical records

Intervention type: PROCEDURE
Intervention: Transbronchial Cryobiopsy Guided by Three-Dimensional Fluoroscopy
Description: Undergo transbronchial cryobiopsy guided by three-dimensional fluoroscopy
Study: NCT05061121

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: combined effect
Description: Compare the short- and mid-term effects of Mulligan's SNAGs, Myofascial release, and their combination on pain intensity, pain pressure sensitivity, cervical function, range of motion (ROM) and postural stability in CNSNP patients

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: combined effect
Description: Compare the short- and mid-term effects of Mulligan's SNAGs, Myofascial release, and their combination on pain intensity, pain pressure sensitivity, cervical function, range of motion (ROM) and postural stability in CNSNP patients

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: combined effect
Description: Compare the short- and mid-term effects of Mulligan's SNAGs, Myofascial release, and their combination on pain intensity, pain pressure sensitivity, cervical function, range of motion (ROM) and postural stability in CNSNP patients
Study: NCT05941468

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AR Dental Care Training System
Description: AR dental care training system is the first training system used in tooth clean skill learning (including Bass method of brushing and inter-dental toothbrush brushing technique) the world, it has been used to training elementary school children and dental hygiene student. And we are the first study to use this system to learn oral cleaning skill in hospital for patient with T2DM.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AR Dental Care Training System
Description: AR dental care training system is the first training system used in tooth clean skill learning (including Bass method of brushing and inter-dental toothbrush brushing technique) the world, it has been used to training elementary school children and dental hygiene student. And we are the first study to use this system to learn oral cleaning skill in hospital for patient with T2DM.
Study: NCT05824468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zimberelimab
Description: Injectable solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Capsule
Study: NCT04768829

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moringa oleifera leaf 10mg/100ml
Description: ear drops

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ear Drop
Description: plain ear drop formulation without moringa
Study: NCT04800900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmaceutical intervention
Description: A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors deprescribe or introduce or remove prescribed drugs
Study: NCT05640583

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hygieacare System
Description: The device is an FDA cleared colon irrigation device, it will be used according to clearance. The sampling of the colon effluent sampled is the are of study.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hygieacare System
Description: The device is an FDA cleared colon irrigation device, it will be used according to clearance. The sampling of the colon effluent sampled is the are of study.
Study: NCT05221385

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gentulizumab
Description: Gentulizumab is administered IV once a week, with every 4 weeks as an administration cycle.
Study: NCT04626791

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Given SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given IV
Study: NCT05587478

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EDP-323
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EDP-323
Description: Oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match EDP-323, oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match EDP-323, oral administration
Study: NCT05661656

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intra-arterial chemoinfusion of breast cancer
Description: Patients will be cannulated via the femoral artery. Then, a 4F fixed-curve catheter (Cobra catheter, Cook Corporation, Bloomington) was advanced to the ipsilateral subclavian artery. Digital subtraction angiography (DSA) was performed to determine tumor arterial blood supply. Super selection of the internal mammary artery done by micro-catheter. Chemo-infusion was decided by the major feeding artery. The intra-arterial chemoinfusion regimen consisted of docetaxel 75 mg/m2 and epirubicin 50 mg/m2 in 200 mL of normal saline and 5% glucose; the drugs were slowly infused via the catheter over at least 15 minutes. Intraarterial infusion was performed once every 3 weeks on average.
Study: NCT06530043

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Senobi exercises
Description: Senobi exercise began with the comfortable sitting of participants with slow inhalation, filling the lungs for a count of 4-5 seconds and holding the breath for 2-3 seconds.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Jacobsons Muscular relaxation exercises
Description: Jacobsons Muscular relaxation exercises started by tensing the muscles in the toes and then moving up the body tensing and relaxing each muscle group in turn (feet and toes, calves, thighs, hips, lower back, upper back, shoulders, arms, hands, neck, and head) and hold it for 5-7 seconds and released it for 5-7 seconds.
Study: NCT04765852

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High dose probiotic supplement
Description: One probiotic stick pack will be dissolved in 10 mL lukewarm formula milk or breastmilk at body temperature. The dissolved supplement will be fed orally, preferably in the morning, starting on Day 1 until Day 56.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low dose probiotic supplement
Description: One probiotic stick pack will be dissolved in 10 mL lukewarm formula milk or breastmilk at body temperature. The dissolved supplement will be fed orally, preferably in the morning, starting on Day 1 until Day 56.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One placebo stick pack will be dissolved in 10 mL lukewarm formula milk or breastmilk at body temperature. The dissolved supplement will be fed orally, preferably in the morning, starting on Day 1 until Day 56.
Study: NCT04626791

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin Hydrochloride
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Given PO

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rituximab and Hyaluronidase Human
Description: Given IV
Study: NCT06381427

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Interdisciplinary decision-making for perioperative care
Description: Interdisciplinary decision-making for perioperative care involving a cardiologist, anesthesiologist, and surgeon in collaboration with the primary care physician. Decisions include determining whether surgery is feasible or if patient optimization is necessary first. Subsequently, targeted postoperative visits by a heart failure nurse and appropriate postoperative care, also after discharge from the hospital, through the primary care physician.
Study: NCT05876208

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BAND Connect's VirtuaCare™ platform
Description: Band Connect provides a medical-grade and condition-specific platform that augments the clinician workflow by extending the in-clinic MSK rehabilitation experience into the patient's home - leading to higher quality personalized treatment and increased adherence with enhanced economics and reimbursement for the clinic.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard of Care Physical Therapy
Description: Standard of care physical therapy without the use of the BAND CVCP
Study: NCT05742399

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic acid NanoGel
Description: Hyaluronic acid nanoparticles (2%)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo gel
Description: conventional gel having the same color, form and packaging
Study: NCT06320899

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SpineShape System IV straight rod elastic
Description: Implantation of SpineShape System IV straight rod elastic

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SpineShape System IV straight rod medium
Description: Implantation of SpineShape System IV straight rod medium (mid-flex)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SpineShape System IV straight rod stiff
Description: Implantation of SpineShape System IV straight rod stiff (low-flex)
Study: NCT05580549

Intervention type: DIAGNOSTIC_TEST
Intervention: Alcohol biomarker Phosphatidylethanol (PEth)
Description: The prevalence of hazardous alcohol use will be mapped through the biomarker PEth and the questionnaire AUDIT.
Study: NCT05138393

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active self-corrective exercises
Description: Scoliosis specific exercises with an Active self-corrective approach. Non-specific physical activity 60 minutes per day.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Observation
Description: Non-specific physical activity 60 minutes per day.
Study: NCT04385082

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Active Cannabis
Description: Smoked cannabis with THC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Active Cannabis
Description: Smoked cannabis with THC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Cannabis
Description: Placebo smoked cannabis (no THC)
Study: NCT05108194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMS Personalized Sleep Intervention
Description: All participants will be enrolled in the intervention to evaluate the feasibility and acceptability of the SMS-PSI. After the data training and validation phase, participants will be provided with at least one and up to three daily text messages that offer users a specific strategy based on strategies from CBTi. All participants will have access to a user dashboard, which is a web-app that includes personalized sleep-tracking information and the opportunity to customize their messaging. The person-level acceptability and adherence to the sleep strategies will be evaluated via self-report endorsement from daily diary and whether users added suggestions to their calendars. Both adherence and acceptability will be collected and integrated with the selection algorithm to optimize subsequent SMS suggestions.
Study: NCT05408494

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gamified behavioral weight loss treatment
Description: 12-month mHealth fully-gamified version of the same program, comprised of a behavior change program with digital reinforcers for attainment of streaks and milestones, and an integrated neurotraining video game

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gamified behavioral weight loss treatment
Description: 12-month mHealth fully-gamified version of the same program, comprised of a behavior change program with digital reinforcers for attainment of streaks and milestones, and an integrated neurotraining video game

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: mHealth behavioral weight loss treatment
Description: a 12-month mHealth weight loss program that includes digital self-monitoring, simplified and self-selected dietary targets, physical activity and a control (sham) non-game neurotraining

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: mHealth behavioral weight loss treatment
Description: a 12-month mHealth weight loss program that includes digital self-monitoring, simplified and self-selected dietary targets, physical activity and a control (sham) non-game neurotraining
Study: NCT05320614

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Web-Based Education
Description: Web-Based Education Information about the operation that the child will undergo; animation films about the hospital, the operating room and the medical equipment to be used; training with presentation including methods of coping with anxiety, fear and pain, postoperative wound care, possible complications in nutrition and nursing care; educational games Education with Therapeutic Play Method Training with the therapeutic game method for 30-45 minutes in the game room in the service one day before the surgery

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine maintenance Training
Description: Explaining the routine care given to the child and parent in the control group by the pediatric surgery nurse in the service.
Study: NCT04468178

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Total joint arthroplasty of the glenohumeral joint
Description: The arthroplasty of the glenohumeral joint will be performed as an anatomical reconstruction after primary or post-traumatic osteoarthritis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Total joint arthroplasty of the glenohumeral joint
Description: The arthroplasty of the glenohumeral joint will be performed as an anatomical reconstruction after primary or post-traumatic osteoarthritis.
Study: NCT06301763

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oral-esophageal Tube Feeding
Description: During the 15-day treatment, both groups of patients are hospitalized, while conventional care and enteral nutrition support are provided to the two groups. Specifically, conventional care includes health education, dietary adjustments, nasopharyngeal hygiene, management of risk factors (blood pressure and lipid control, etc.), exercise rehabilitation, and psychological support. The frequency and content of these interventions are arranged based on the health condition.The observation group receives Intermittent Oral-esophageal Tube Feeding for enteral nutrition support (developed by the Dysphagia Institute of Zhengzhou University, CN201821314797.2), which is made of silicone material, 40 cm long, with an inner diameter of 0.54 cm.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: nasogastric tube feeding
Description: During the 15-day treatment, both groups of patients are hospitalized, while conventional care and enteral nutrition support are provided to the two groups. Specifically, conventional care includes health education, dietary adjustments, nasopharyngeal hygiene, management of risk factors (blood pressure and lipid control, etc.), exercise rehabilitation, and psychological support. The frequency and content of these interventions are arranged based on the health condition.The control group is provided with nutritional support as nasogastric tube feeding, performed 6-10 times per day according to relevant guidelines, with an interval of more than 2 hours between every two feedings, and a feeding volume not exceeding 200 ml per time.
Study: NCT05229549

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: GOLIKE PLUS 3-16
Description: PKU GOLIKE PLUS 3-16 is a food for special medicinal purposes (FSMP) for the dietary management of PKU.
Study: NCT05587322

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLI5100
Description: Orally via tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLI5100
Description: Orally via tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Orally via tablet
Study: NCT05229549

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: GOLIKE PLUS 3-16
Description: PKU GOLIKE PLUS 3-16 is a food for special medicinal purposes (FSMP) for the dietary management of PKU.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Free AAs
Description: It is an immediate-release free AAs mixture with the same qualitative and quantitative composition of PKU GOLIKE PLUS 3-16.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Free AAs
Description: It is an immediate-release free AAs mixture with the same qualitative and quantitative composition of PKU GOLIKE PLUS 3-16.