TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05801224

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nitric Oxide
Description: 20ppm for 15 minutes delivered by INO max(Nitric Oxide) Company : INO therapeutics, Inc.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nitric Oxide
Description: 20ppm for 15 minutes delivered by INO max(Nitric Oxide) Company : INO therapeutics, Inc.
Study: NCT06551714

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Phase 1 cardiac rehabilitation
Description: Day 1:Patients were informed about the surgery, positioning and mobilization.Range of motion (ROM), respiratory control, diaphragmatic breathing, pursed lip breathing, thoracal expansion exercises, assisted coughing,forced expiration techniques, which are the components of active breathing techniques cycle (ABTC), were taught.The use of incentive spirometry (IS) was demonstrated.Patients were performed 10 repetitions of IS exercises, and 5 repetitions ABTC and were asked to repeat them every hour.The patient was made to sit for 10 minutes and was walked 60 meters twice a day.~2:ROM, IS and diaphragmatic breathing exercises were applied 10 times each.ABTC was repeated in 5 sets. 120 meters was walked 5 times during the day.~3:Sitting time was increased to 30 minutes and walking distance was increased to 240 meters.5 steps were climbed.~4:Walking distance was increased to 360 meters.One flight of stairs was climbed.Discharge training was given.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Phase 1 cardiac rehabilitation
Description: Day 1:Patients were informed about the surgery, positioning and mobilization.Range of motion (ROM), respiratory control, diaphragmatic breathing, pursed lip breathing, thoracal expansion exercises, assisted coughing,forced expiration techniques, which are the components of active breathing techniques cycle (ABTC), were taught.The use of incentive spirometry (IS) was demonstrated.Patients were performed 10 repetitions of IS exercises, and 5 repetitions ABTC and were asked to repeat them every hour.The patient was made to sit for 10 minutes and was walked 60 meters twice a day.~2:ROM, IS and diaphragmatic breathing exercises were applied 10 times each.ABTC was repeated in 5 sets. 120 meters was walked 5 times during the day.~3:Sitting time was increased to 30 minutes and walking distance was increased to 240 meters.5 steps were climbed.~4:Walking distance was increased to 360 meters.One flight of stairs was climbed.Discharge training was given.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Neurophysiological facilitation techniques
Description: In addition to the phase 1 cardiac rehabilitation program for the group receiving neurophysiological facilitation (NPF) techniques:~NPF techniques such as perioral stimulation, intercostal tension, anterior basal lift, vertebral pressure, moderate manual pressure and abdominal co-contraction were applied for ten times for ten seconds.~Diaphragm facilitation exercise was performed by inhaling against resistance and holding the breath against resistance for 5 seconds.~Unilateral and bilateral upper extremity proprioceptive neuromuscular facilitation (PNF) movements combined with breathing were performed.~NPF techniques were performed 10 times each day throughout the treatment, while other applications (diaphragm facilitation, combined breathing exercise with upper extremity PNF technique and respiratory facilitation) were performed 5 times on the first day and 10 times on the other three days.
Study: NCT04684472

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Modified anti-CD19 CAR T cells
Description: intravenous infusion
Study: NCT05385549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imatinib Mesylate
Description: Imatinib Mesylate, 400 mg once daily, oral. 5 years of adjuvant imatinib treatment (standard treatment 3years + IP treatment : 2yesrs)
Study: NCT05570890

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Foam
Description: The foam will be used to make an unstable surface.
Study: NCT05840107

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GC012F injection
Description: GC012F injection is an autologous dual CAR-T targeted BCMA and CD19. A single infusion of CAR-T cells will be administered intravenously
Study: NCT06488339

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein and oil supplement
Description: Take 1 sachet/day replaced dinner
Study: NCT05585398

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IncobotulinumtoxinA
Description: Intradermal injections using different delivery methods (conventional needle and microneedles)
Study: NCT05810428

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: GKRS-VR training
Description: One month after radiosurgery, GKRS-VR subjects will receive neuromodulation treatment twice a week (30' per time), for 8 consecutive weeks followed by 9 months of remote rehabilitation. GKRS-VR group will perform neuromodulation based on VR sensorimotor rehabilitation using an immersive system developed ad-hoc. Treatments will include voluntary mimic movements reinforced by VR augmented feedback, consisting in the reflection of a real-time avatar animation, multiplied when needed, associated with different targets to reach based on specific facial gestures. The execution of motion multiplier on avatar will be allowed in order to personalize treatments, emphasizing a graded exposure to pain perception. In addition, the investigators will develop a dedicated mobile-application for remote rehabilitation with the aim of prescribing VR augmented feedback home exercises and immersive VR pain neuromodulation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: Control Group will undergo only radiosurgery with no rehabilitation and they will perform only clinical evaluation at study entry, after three months and one year.
Study: NCT05593497

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capivasertib
Description: 400 mg (2 tablets) BID given on an intermittent weekly dosing schedule. Patients will be dosed on Days 1 to 4 in each week (4 days on, 3 days off). Treatment will be given in combination with abiraterone for 16 weeks duration (+/- 1 week for surgery window).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: abiraterone acetate
Description: Administered orally as tablets at a dosage of 1000 mg daily. To be administered with prednisone 5mg po daily.~Subjects will be on concurrent GNRH agonist therapy (leuprolide, administered as standard of care). Intensified androgen deprivation (iADT) consisting of abiraterone and leuprolide will be administered for a 4 week run-in prior to addition of capivasertib.
Study: NCT06246318

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality
Description: The virtual reality protocol here is based on perceptual-motor activities, supported by Nintendo Wii resources. The user will be able to control a game character in a virtual environment using a remote control with a motion sensor. Wii Fit Plus requires the use of the Wii Balance Board that the player stands on during gameplay. The Wii Balance Board is not a wobbly balance board, but is able to detect and track the user's center of balance, a feature used extensively in the game. Wii Fit Plus includes more than 40 activities including yoga, strength training, aerobics and balance games. During the virtual reality application, different games will be preferred in each session depending on the duration of the games. Virtual reality application will be carried out in a corner prepared for virtual reality application in the room where the conventional occupational therapy session is held. Families have the right to observe and attend all sessions whenever they wish.

Intervention type: OTHER
Group type: OTHER
Intervention: conventional occupational therapy
Description: Sensory integration and gross motor training approaches will be used in the conventional occupational therapy program. A manualized protocol based on Ayres sensory integration principles will be followed (Schaaf et al., 2012). The intervention will be carried out by a licensed occupational therapist trained in sensory integration.~This approach suggests that if a child engages in individually adapted sensorimotor activities, the nervous system is better able to modulate, organize, and integrate sensory information and is also more likely to use sensory information in adaptive ways (Ayres, 1972). Components of the intervention include a sensory-rich, playful, child-centered approach, providing a decision challenge, and facilitating increasingly complex adaptive behaviors by engaging the child in individually tailored, developmentally appropriate play interactions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional occupational therapy
Description: Sensory integration and gross motor training approaches will be used in the conventional occupational therapy program. A manualized protocol based on Ayres sensory integration principles will be followed (Schaaf et al., 2012). The intervention will be carried out by a licensed occupational therapist trained in sensory integration.~This approach suggests that if a child engages in individually adapted sensorimotor activities, the nervous system is better able to modulate, organize, and integrate sensory information and is also more likely to use sensory information in adaptive ways (Ayres, 1972). Components of the intervention include a sensory-rich, playful, child-centered approach, providing a decision challenge, and facilitating increasingly complex adaptive behaviors by engaging the child in individually tailored, developmentally appropriate play interactions
Study: NCT05896852

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: physical activity
Description: Participants will increase their physical activity through walking.
Study: NCT06230978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Habit workup
Description: The patient and pharmacist will work together to specify a cue to help them take their medicine every day (e.g. brushing teeth, getting dressed, eating breakfast, making coffee, alarms, visual reminders etc).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Medication Counseling
Description: The pharmacist provides standard counseling on the new medication
Study: NCT05230433

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: High-fat Challenge
Description: The shake will be composed of a mixture of BOOST Glucose Control(R) (Nestlé Products) supplemented with palm oil. Each participant will consume a volume of liquid equivalent to 25% of their estimated daily caloric needs, calculated by the USDA Dietary Reference Intakes using a moderate activity factor.
Study: NCT06340984

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Montelukast 10 Mg Oral Tablet
Description: group modrate and severe acne will receive Montelukast therapy , dose: 10mg/day, duration of therapy: three months., Quantitively assay of level of serum intercellular adhesion molecule -1 will be measured by performing an enzyme-linked immune sorbent assay (E LISA) in group moderate acne vs group severe acne pre Montelukast treatment and after three months of treatment vs control group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Montelukast 10 Mg Oral Tablet
Description: group modrate and severe acne will receive Montelukast therapy , dose: 10mg/day, duration of therapy: three months., Quantitively assay of level of serum intercellular adhesion molecule -1 will be measured by performing an enzyme-linked immune sorbent assay (E LISA) in group moderate acne vs group severe acne pre Montelukast treatment and after three months of treatment vs control group
Study: NCT06305169

Intervention type: DIAGNOSTIC_TEST
Intervention: Gastropanel
Description: Gastropanel is a commercially available blood test which given serum levels of pepsinogen I and II and gastrin 17 along with helicobacter pylori infection status
Study: NCT06230978

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Medication Counseling
Description: The pharmacist provides standard counseling on the new medication
Study: NCT04649047

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal-oriented episodic future thinking
Description: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Study: NCT06419972

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: multimodal physiotherapy programme
Description: The intervention to which the climacteric women will be subjected will consist of a combined program of education and general strength and pelvic floor muscles exercises of 8 weeks duration, at a rate of 2 sessions/week. Each of the sessions will last 60 min, except for the first one, which will be 90 min.
Study: NCT06179420

Intervention type: OTHER
Intervention: total cumulative gonadotrophin usage
Description: total dosage in IU

Intervention type: OTHER
Intervention: total cumulative gonadotrophin usage
Description: total dosage in IU
Study: NCT05368116

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video Assisted Self Management Program
Description: The main aim of this intervention is to educate the cancer patients receiving chemotherapy regarding the management of chemotherapy related side effects.~It will be one to one teaching session of 10-20 minutes conducted by the principal researcher with the help of a video on self management of chemotherapy related side effects and the video will focus on the self management of selected side effects of chemotherapy including nausea vomiting , Diarrhea , Fever , Mucositis , Skin changes , and Alopecia related distress.~The participants were given video when they comes to the Oncology day care and researcher instructs the participants to watch the video and at the same time the doubts asked by the participants were cleared by the researcher.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Standard of care
Study: NCT06633120

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IVM
Description: Immature oocytes will be retrieved from small ovarian follicles and matured overnight in the laboratory prior to undergoing fertilization and embryo culture.
Study: NCT05009511

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning through feedback
Description: The goal of this investigation is to examine the influence of feedback timing on learning and brain function.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning through feedback
Description: The goal of this investigation is to examine the influence of feedback timing on learning and brain function.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning through feedback
Description: The goal of this investigation is to examine the influence of feedback timing on learning and brain function.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning through feedback
Description: The goal of this investigation is to examine the influence of feedback timing on learning and brain function.
Study: NCT05190861

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: droplet digital PCR method
Description: The droplet digital PCR method can detect nucleic acids from the most common pathogens (approximately 90%) responsible for BSIs according to Chinet2020 and takes about 4 hours to perform, reporting within the first 24h of suspected sepsis/septic shock.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: blood culture
Description: Blood culture is a conventional microbiological method of pathogen detection. Results from blood cultures are usually not available until 24 to 72 hours after sampling.
Study: NCT04836676

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: C-REX Device
Description: The investigational devices are C-REX LapAid Cath or C-REX RectoAid Cath. C-REX LapAid Cath consists of an invasive surgical part, i.e. anastomotic ring comprised of two LapAn coupled by DMC/DM, intended for short-term use, and surgical instruments for assisting the placement of the anastomotic ring to intestine.~C-REX RectoAid Cath consists of an invasive surgical part, i.e. an anastomotic ring comprised of RectoAn and LapAn, intended for short-term use, and surgical instruments for assisting the placement of the anastomotic ring to intestine.~C-REX LapAid Cath and C-REX RectoAid Cath are easy to use, with unique possibility to control and validate the integrity of the anastomosis during and after surgery.
Study: NCT06429462

Intervention type: DIAGNOSTIC_TEST
Intervention: smartphone camera sensor tool
Description: The study will involve the development and validation of a computer vision-based approach (using cameras to assess movements) to monitor knee flexion and extension, and a walking pattern assessment.

Intervention type: DIAGNOSTIC_TEST
Intervention: smartphone camera sensor tool
Description: The study will involve the development and validation of a computer vision-based approach (using cameras to assess movements) to monitor knee flexion and extension, and a walking pattern assessment.
Study: NCT04945967

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: New Method
Description: Physiological flexion in therapeutic positioning, oral stimulation, stimulation of synergistic movements, and stimulation for non-nutritive sucking by using special designed pacifier for premature infant.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Method
Description: Oral stimulation and non-nutritive sucking stimulation using usual pacifier.
Study: NCT05895903

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Screw expander
Description: threadform screw expanders with special condensing burs for lateralization and compaction of bone

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Osseodensification drills
Description: special drills to expand narrow alveolar ridges.
Study: NCT05473286

Intervention type: DRUG
Intervention: Oral Semaglutide
Description: Patients will be treated with commercially available oral semaglutide according to local label and to routine clinical practice at the discretion of the treating physician. The decision to initiate treatment with commercially available oral semaglutide has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician based on local label before and independently from the decision to include the patient in this study.
Study: NCT05205369

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 10-week home-based Yi Jin Bang exercise program
Description: Each participant in this group will do a home-based Yi Jin Bang exercise program four times a week for ten consecutive weeks, which consists of ten minutes of warm-up, 18 minutes of Yi Jin Bang exercise (ten exercises), and ten minutes of cool-down. To learn how to conduct the home-based exercise session, each participant will be invited to one introductory session before starting the prescribed exercise program. Two experienced Yi Jin Bang instructors will lead the introductory session. Besides, in order to monitor participants' adherence and help them to conduct self-training, we will use the Zoom Meeting application. Zoom can capture and record participants' movements through the webcam. During the introduction sessions, we will teach participants how to use Zoom. Furthermore, we will provide support for adherence to the home exercise sessions through telephone calls or e-mail every two weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 10-week home-based usual exercise therapy program
Description: Among exercise therapy in the treatment of SAPS, stretching and strengthening protocols are often used . Therefore, participants in this group will do a standardized home-based stretching and strengthening exercise program four times per week for ten weeks, which is set up according to a previous study. This program has been demonstrated that can be effective in reducing pain and improving function in patients with SAPS. For strengthening exercises, elastic bands will be used. To learn how to conduct the self-training program, each participant in this group will also be invited to one introductory session before starting the prescribed exercise training. Two certificated physiotherapists will lead the introductory session. In addition, a video demonstration clip will be given to each participant to provide a home reference, and the Zoom Meeting application will be used to help monitor the exercise.
Study: NCT05414955

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neuromodulation
Description: Neuromodulation
Study: NCT05361642

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl 0.5% Injectable Solution
Description: using nasal block including sphenopalatine ganglion block with general anesthesia to optimize surgical field

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: using dexmedetomidine with induction of general anesthesia to optimize surgical field
Study: NCT06263049

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: transurethral resection of prostate
Description: resection of prostate by using bipolar cautarization

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: transurethral resection of prostate
Description: resection of prostate by using bipolar cautarization
Study: NCT05718193

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DeFrame
Description: The DeFrame system is applicated during colonoscopy. The DeFrame system superimposes a rectangular box on the polyp lesion area in the colonoscopy field of view, notifying the endoscopists of the presence of the lesion.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Classified DeFrame
Description: The Classified DeFrame system is applicated during colonoscopy. The Classified DeFrame system superimposes a rectangular box on the polyp lesion area in the colonoscopy field of view, the color of the rectangle box will turn blue when the polyp is considered as an adenoma, notifying the endoscopists of the presence of the lesion.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: conventional colonoscopy
Description: conventional colonoscopy