TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05701865

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol Intoxication- Ascending Limb
Description: Participants will be assigned to moderate alcohol dose condition (target breath alcohol concentration .08%) with NIAAA approved alcohol administration procedures and complete the study task on the ascending limb

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol Intoxication- Descending Limb
Description: Participants will be assigned to moderate alcohol dose condition (target breath alcohol concentration .08%) with NIAAA approved alcohol administration procedures and complete the study task on the descending limb

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: No Alcohol Control
Description: Participants will be assigned to a no alcohol control condition
Study: NCT05281874

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive Change (+Change)
Description: This is an integrated social norms-based personalized feedback intervention for college students targeting alcohol misuse and sexual assault. It targets alcohol, sexual assault victimization risk, sexual assault perpetration, and bystander intervention. It is tailored by gender and sexual orientation.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: A healthy lifestyles attention control
Description: A healthy lifestyles attention control will be used as the control condition. We will match the control and intervention conditions on content (text, pictures, number of pages); type (interactive vs. psychoeducation); and average completion time.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive Change (+Change) Plus Booster
Description: Positive Change (+Change) Plus Booster
Study: NCT06770933

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be supplied as a tablet identical to test drug but without VX-01. Placebo packaging will be identical to IP in order to keep study personnel and subjects masked.
Study: NCT06775054

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Magnetic Stimulation
Description: Transcranial Magnetic Stimulation (TMS) is a noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain. It is primarily used to treat depression, particularly in patients who have not responded to traditional treatments such as selective serotonin reuptake inhibitors (SSRIs) or psychotherapy. The most common target area is the dorsolateral prefrontal cortex, which is often underactive in individuals with depression. TMS devices, such as the FDA-approved Magventure system, deliver magnetic pulses to stimulate or inhibit brain activity in the targeted region. This process is believed to help reset or normalize patterns of neural activity associated with depression and other psychiatric disorders. TMS offers a promising alternative for individuals struggling with depression, providing a non-invasive approach with relatively few side effects and notable potential benefits.
Study: NCT05156294

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NovoMatrix
Description: Implants of Camlog Conelog Screw-Line Promote Plus will be placed. Implants will be placed 1 mm below the bone crest. The diameter of the implant will be in the range of 3.8 and 4.3 mm. Consecutively, 4 to 6 mm height healing abutments and the allogenic membrane (NovoMatrix®, BioHorizon) folded in two on top of the implant (secured with the healing abutment), will be placed. Finally, flaps will be sutured with 6/0 polypropylene monofilament. Patients will be instructed to rinse with 15 ml of 0.12% chlorhexidine (Perio-Aid tratamiento, Dentaid SL, Barcelona, Spain) 60 seconds twice per day until suture removal, that will take place 14 days later. Anti-inflammatory drugs will also be prescribed (Ibuprofen 600 mg every 8 hours upon patient´s needs).

Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: Implants of Camlog Conelog Screw-Line Promote Plus will be placed. Implants will be placed 1 mm below the bone crest. The diameter of the implant will be in the range of 3.8 and 4.3 mm. Finally, flaps will be sutured with 6/0 polypropylene monofilament. Patients will be instructed to rinse with 15 ml of 0.12% chlorhexidine (Perio-Aid tratamiento, Dentaid SL, Barcelona, Spain) 60 seconds twice per day until suture removal, that will take place 14 days later. Anti-inflammatory drugs will also be prescribed (Ibuprofen 600 mg every 8 hours upon patient´s needs).
Study: NCT05130307

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: virtual reality game
Description: participants interact with a computer generated world

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: virtual reality game
Description: participants interact with a computer generated world
Study: NCT06108362

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Terlipressin
Description: The medication is dispensed by the nursing staff before surgery and given to the anesthesiologist before the procedure begins

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: The medication is dispensed by the nursing staff before surgery and given to the anesthesiologist before the procedure begins
Study: NCT06399926

Intervention type: DRUG
Intervention: Pemetrexed injection
Description: Group 1（20mg）:induction stage is 20 mg per 24 hours for 72 hours, every 2 weeks; consolidation stage is 20mg per 24 hours for 72 hours, every 3 weeks.

Intervention type: DRUG
Intervention: Pemetrexed injection
Description: Group 1（20mg）:induction stage is 20 mg per 24 hours for 72 hours, every 2 weeks; consolidation stage is 20mg per 24 hours for 72 hours, every 3 weeks.

Intervention type: DRUG
Intervention: Pemetrexed
Description: Group 2（30mg）:induction stage is 30 mg D1，every week.Consolidation stage is 30 mg D1,every 3 weeks.

Intervention type: DRUG
Intervention: Pemetrexed
Description: Group 2（30mg）:induction stage is 30 mg D1，every week.Consolidation stage is 30 mg D1,every 3 weeks.
Study: NCT05150366

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Trans thoracic echocardiography
Description: trans thoracic echocardiography at the beggining and at the end of the placement of the Saint Jude Medical AMULET type prosthesis
Study: NCT06773156

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab + Apatinib
Description: Adebrelimab: Administered by intravenous infusion at a fixed dose of 1200 mg. The infusion should be completed within 30-60 minutes, with a maximum duration of 2 hours. The first dose is given on Day 1, with subsequent doses repeated every 3 weeks. Dose adjustments (either up or down) are not allowed during the study. A maximum delay of 9 weeks for treatment is allowed, or treatment may be terminated.~Apatinib: 250 mg, taken orally after meals, once daily, continuously. The investigator may temporarily pause the dose or adjust the administration schedule based on symptomatic treatment, such as changing to an every-other-day (qod) schedule or a 5-day-on, 2-day-off regimen. Once toxicity resolves, treatment may resume at the original dose.~The combined treatment of Adebrelimab + Apatinib for consolidation therapy should not exceed 24 months in total.
Study: NCT06773351

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane 0 + different doses of ciprofol
Description: Sevoflurane 0% combined with ciprofol 0.1, 0.2, 0.3, 0.4, 0.6mg/kg, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane 0.7% + different doses of ciprofol
Description: Sevoflurane 0.7% combined with ciprofol 0.1, 0.2, 0.3, 0.4, 0.5mg/kg, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane 1.0% + different doses of ciprofol 0.05
Description: Sevoflurane 1.0% combined with ciprofol 0.05, 0.1, 0.2, 0.3, 0.4mg/kg, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane 1.5% + differnet doses of ciprofol
Description: Sevoflurane 1.5% combined with ciprofol 0.05, 0.1, 0.2, 0.3, 0.4mg/kg, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane 2.0% + different doses of ciprofol
Description: Sevoflurane 2.0% combined with ciprofol 0.05, 0.1, 0.15, 0.2, 0.3mg/kg, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane 2.5% + different doses of ciprofol
Description: Sevoflurane 2.5% combined with ciprofol 0.05, 0.1, 0.15, 0.2, 0.3mg/kg, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol 0 + different end-expiratory concentration of sevoflurane
Description: Ciprofol 0 combined with sevoflurane 0.7, 1.5, 2.0, 2.5, 3.5%, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol 0.05mg/kg + different end-expiratory concentration of sevoflurane
Description: Ciprofol 0.05 mg/kg combined with sevoflurane 0.7, 1.5, 2.0, 2.5, 3.5 %, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol 0.1mg/kg + different end-expiratory concentration of sevoflurane
Description: Ciprofol 0.1mg/kg combined with sevoflurane 0.5, 1.5, 2.0, 2.5, 3.0 %, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol 0.2 mg/kg + different end-expiratory concentration of sevoflurane
Description: Ciprofol 0.2 mg/kg combined with sevoflurane 0.5, 1.5, 2.0, 2.5, 3.0 %, respectively.
Study: NCT05596019

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: specific neurodynamic exercises
Description: Specific neurodynamic exercises in women older than 65 years with neck pain
Study: NCT04931888

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EMPOWER
Description: EMPOWER is an adapted social emotional learning (SEL) and wellness education initiative delivered to a community of refugee families that was developed through a pre-pilot in the New Haven Afghan refugee community in 2020. Unlike traditional school-based SEL curricula, EMPOWER partners with community organizations to provide translated and trauma-informed wellness education to family units. The program combines in-person (socially distant) and remote delivery of culturally-informed physical, emotional, and medical wellness tools adapted from evidenced-based behavioral medicine, refugee trauma and recovery, and community health research.
Study: NCT06773351

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol 0.3 mg/kg + different end-expiratory concentration of sevoflurane
Description: Ciprofol 0.3 mg/kg combined with sevoflurane 0.5, 1.0, 1.5, 2.0, 2.5 %, respectively.
Study: NCT04931888

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: EMPOWER
Description: EMPOWER is an adapted social emotional learning (SEL) and wellness education initiative delivered to a community of refugee families that was developed through a pre-pilot in the New Haven Afghan refugee community in 2020. Unlike traditional school-based SEL curricula, EMPOWER partners with community organizations to provide translated and trauma-informed wellness education to family units. The program combines in-person (socially distant) and remote delivery of culturally-informed physical, emotional, and medical wellness tools adapted from evidenced-based behavioral medicine, refugee trauma and recovery, and community health research.
Study: NCT05607212

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kettlebell Swing
Description: Participants will perform two-handed kettlebell swings using the interval training protocol outlined in the study carried out by Jay et. al. (2011). The protocol calls for 30 seconds of work, followed by 30-60 seconds of rest for a total of 10 intervals. The mechanics of the kettlebell swing will follow those outlined in the study carried out by McGill et. al. (2012). All male participants will perform the intervention with a 16kg kettlebell and all female participants will perform the intervention with a 12kg kettlebell to assure reliability. The weight is higher than previous and similar study by Brandon et al to ensure measurable differences between experimental and comparison groups.
Study: NCT06773351

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol 0.4 mg/kg + different end-expiratory concentration of sevoflurane
Description: Ciprofol 0.4 mg/kg combined with sevoflurane 0.5, 1.0, 1.5, 2.0, 2.5 %, respectively.
Study: NCT06774248

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Youth Opioid Recovery Support (YORS)
Description: The Youth Opioid Recovery Support (YORS) model is an innovative wrap-around approach that attempts to address barriers to medication adherence in this vulnerable young adult population. The YORS intervention primary components are (as detailed below):~1. Low barrier access to MOUD, including home delivery, ride-share app transportation and mobile van delivery and low barrier access to MOUD in general~2. Engagement of families in collaborative treatment planning and monitoring with a focus on medication adherence~3. Assertive continuing care: actively tracking and communicating with youth and families by text and social media to promote engagement and adherence~4. Contingency management: to provide incentives for medication adherence
Study: NCT05607212

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isometric Hold
Description: Participants will perform an isometric hold of a kettlebell for 30 seconds followed by 30 seconds of rest for a total of 10 intervals. Participants will mimic initial kettlebell swing position by standing shoulder width apart with their back straight, and hips and knees flexed. Participants will be cued to squeeze their glutes and look straight ahead while they hold the weight for the 30 second interval. All male participants will perform the intervention with a 16kg kettlebell and all female participants will perform the intervention with a 12kg kettlebell to assure reliability.

Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: Control group: participants will be educated on the benefit of a kettlebell swing.
Study: NCT05596019

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: multimodal exercise
Description: Multimodal and nonspecific exercises in women older than 65 years with neck pain
Study: NCT06342674

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Giving breast milk to the newborn according to the circadian rhythm
Description: It is the delivery of milk expressed by the newborn's mother during the neonatal intensive care unit, in accordance with the time of expression. Breast milk follows the circadian rhythm, that is, the milk the mother expresses at night will be given to her infant at night, and the milk she expresses during the day will be given to her infant during the day

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Newborns in the control group will be given expressed milk first, in line with the routine practice of the clinic
Study: NCT05638048

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Precision grip training
Description: First determine patients for holding the ball movement should reach the effective blood flow velocity and best duration - relaxation, and USES the electronic grips and color doppler ultrasonic diagnostic apparatus, for individual patients to choose the best grip the efforts and training, to form the best grip the training plan, and observe the scheme for Peripheral central venous catheter-associated thrombosis prevention effect.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Use maximum strength grip training
Description: Patients were routinely implanted with PICC, and on the basis of health education in the control group, the best continuous-relaxation time, frequency and maximum grip strength of patients were used for grip strength training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health education on routine grip strength training
Description: Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.
Study: NCT06549205

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: device that stimulates the dorsal surface of the tongue
Description: the device will be placed on the dorsal surface of the tongue. this instrument has two electrodes in turn connected to the TENS, so ultra low frequency stimulation (\<0.66 Hz) will be administered

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: device that stimulates the tragus
Description: two electrodes will be placed at tragus level for the administration of dental ULFTENS
Study: NCT04922411

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: STN DBS
Description: PD patients with DBS STN will be scanned and tested with DBS ON and OFF
Study: NCT05730179

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical Conditioning stimulus
Description: Painful mechanical stimulus

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical Conditioning stimulus
Description: Painful mechanical stimulus

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical Conditioning stimulus
Description: Painful mechanical stimulus
Study: NCT06770829

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DiaFOOTCare Program
Description: The DiaFOOTCare Program includes initiatives to support diabetic foot self-management. An e-booklet on type 2 diabetes management and preventive foot care will be shared via WhatsApp or email, along with audio modules for convenient access. An interactive video featuring a simulated patient will visually demonstrate preventive foot care practices and will also be shared digitally. A 25-30-minute face-to-face training session will provide personalized education using a tablet. Goal-tracking cards will be introduced to collaboratively set three-month behavioral goals, with patients documenting their progress during the follow-up. SMS reminders will be sent three times weekly to reinforce adherence. Patients will have digital access to all DiaFOOTCare resources, including the e-booklet, audio modules, and video, for 12 weeks, ensuring accessibility via WhatsApp or email. These measures aim to enhance knowledge, behavior, and self-management practices in preventive diabetic foot care.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Ministry of Health and Education
Description: The active control group will receive routine outpatient follow-ups and a diabetic foot care brochure from the Ministry of Health, explained by the researcher and shared via WhatsApp or email for reference. Goal-tracking cards from the DiaFOOTCare program will be used to set individual diabetic foot self-management behavioral goals collaboratively during the initial interview. Patients will be instructed on how to complete the cards and maintain them over a three-month period. At the end of the follow-up, post-tests will assess outcomes using the Glycemic Control Form, Goal-Tracking Card, Diabetic Foot Knowledge Scale, Foot Care Behavior Scale, Nottingham Functional Foot Care Diagnostic Form, Diabetic Foot Development Follow-up Form, and Diabetic Foot Self-Management Scale. Educational resources, including the e-booklet, audio modules, and video developed in DiaFOOTCare, will also be shared via WhatsApp or email to provide additional support and enhance diabetic foot self-management.
Study: NCT05929612

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Ultra Low Dose 4 Gy Radiation
Description: 4 Gy in 2 fractions
Study: NCT06435273

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD4604
Description: Janus kinase 1 (JAK1) inhibitor

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo to AZD4604
Description: Placebo to AZD4604
Study: NCT05684380

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MAZ-101association
Description: Experimental drug

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DYMISTA®
Description: Active comparator
Study: NCT05379101

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance image (CMR)
Description: A magnetic resonance imaging study for assessment of cardiac structure and intracardiac flow

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance image (CMR)
Description: A magnetic resonance imaging study for assessment of cardiac structure and intracardiac flow
Study: NCT06174142

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High-Frequency ESWT
Description: Participants will receive extracorporeal shock wave therapy at a frequency of 15 Hz and intensity/pressure level 3, with a total of 1800 impulses per session. This intervention will be conducted once per week for six weeks, alongside a standard physical therapy regimen

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-Frequency ESWT Group
Description: Participants will be treated with extracorporeal shock wave therapy at a frequency of 10 Hz and intensity/pressure level 4, also with a total of 1800 impulses per session. This protocol will be delivered weekly for six sessions, accompanied by standardized physical therapy exercises.
Study: NCT05379101

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance image (CMR)
Description: A magnetic resonance imaging study for assessment of cardiac structure and intracardiac flow

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance image (CMR)
Description: A magnetic resonance imaging study for assessment of cardiac structure and intracardiac flow

Intervention type: DIAGNOSTIC_TEST
Intervention: Transthoracic Echocardiogram (TTE)
Description: An imaging test that uses soundwaves that cannot be heard (ultrasound) to take pictures of the heart and vessels.

Intervention type: DIAGNOSTIC_TEST
Intervention: Transthoracic Echocardiogram (TTE)
Description: An imaging test that uses soundwaves that cannot be heard (ultrasound) to take pictures of the heart and vessels.
Study: NCT06068972

Intervention type: DEVICE
Intervention: MolecuLight
Description: Point-of-care fluorescence imaging of high bacterial loads
Study: NCT05102526

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Young Millie prevention program, active teachers
Description: Prevention program: Young Mili, in collaboration with the teacher

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevention program: Young Mili, non active teachers
Description: Prevention program: Young Mili, without the participation of the teacher
Study: NCT06174142

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham ESWT Control Group
Description: Participants in this control group will undergo a sham ESWT procedure that mimics the treatment experience without actual therapeutic effects, ensuring the blinding of participants. This sham therapy will be scheduled once a week for six weeks, in conjunction with the same physical therapy program as the other groups.