TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06724445

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Thabo cartoon
Description: The animated cartoon features Thabo, a Black South African man living with HIV. Through his narrative, viewers follow his daily experiences managing his condition and confronting societal stigma in a South African context. The story explores his interactions with family, friends, and community members, highlighting both challenges and moments of resilience. The animation concludes with Thabo delivering an anti-stigma message directly to viewers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Steve cartoon
Description: The animated cartoon follows Steve, a White man living with HIV. His narrative parallels Thabo's, showing his daily experiences managing HIV and facing societal stigma. The story depicts his interactions with family, friends, and community members, presenting the same situations and challenges as in Thabo's story. The animation ends with Steve delivering the same anti-stigma message to viewers.
Study: NCT06722898

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Supplement
Description: Contains ingredients believed to reduce Blood Alcohol Concentration and symptoms of alcohol impairment.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06724653

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RAS blocker tapering group
Description: RAS blocker tapering out

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: RAS blocker tapering group
Description: RAS blocker tapering out

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RAS blocker tapering group
Description: RAS blocker tapering out

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Beta blocker tapering out
Description: Beta blocker tapering out group

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Beta blocker tapering out
Description: Beta blocker tapering out group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Beta blocker tapering out
Description: Beta blocker tapering out group
Study: NCT06724003

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Computer-based virtual reality simulation
Description: The computer-based virtual practice simulation was created as a single scenario for oral care practice in the unconscious patient. The scenario software was created and designed by the researcher who is an IT specialist. In the formation phase of the scenario, the software was realized by working together with the researcher, the expert faculty member, the nurse and the informatics specialist for the photographs required for the virtual reality application and the steps of the scenario software.
Study: NCT03527069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cipros 10 association
Description: oral, once a day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Crestor 10 mg
Description: oral, once a day.
Study: NCT05868369

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iVR Group
Description: On the day of surgery, the iVR group will receive a 30-minute sessions or dose of iVR therapy in the ambulatory post-anesthesia care unit (PACU) during their stay. The three distraction-based or skills-based iVR modules will consist of either 1) Mindful Escape; 2) Empowered Breathing; or 3) Relaxation videos. The iVR group will be sub-randomized into receiving only one of the three types of modules. The modules will start approximately 30 minutes upon arriving in PACU and will last approximately 30 minutes.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard pain management regimen
Description: In the ambulatory post-anesthesia care unit (PACU) during their stay with have standard postoperative pain protocol (including a pre-operative local field block).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard pain management regimen
Description: In the ambulatory post-anesthesia care unit (PACU) during their stay with have standard postoperative pain protocol (including a pre-operative local field block).
Study: NCT06724263

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: B1962
Description: B1962 has higher VEGF anti angiogenic activity than its competitors. Phase I clinical trials have shown that B1962 has excellent safety and promising therapeutic effects. Large scale clinical studies may achieve better therapeutic effects than similar competitors targeting the same target
Study: NCT06723769

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: rTMS treatment
Description: Repetitive transcranial magnetic stimulation (rTMS) is a new physiotherapy technique for the treatment of PSD Compared to other strategies, it has the advantages of simple operation, non-invasive, painless, and safe. Studies have comprehensively shown that rTMS can effectively improve depressive symptoms in PSD patients

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional treatment
Description: general treatment of stabilizing vital signs (such as antidepressants, stabilizing blood pressure, stabilizing blood sugar, etc. ) and conventional rehabilitation treatment (hemiplegic limb comprehensive training, swallowing speech training, cognitive perception training, etc. ).
Study: NCT06722456

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of protein signatures in stool samples
Description: Stool protein signatures are to be established in parallel to standard clinical evaluation of the intestinal inflammatory activity.

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of protein signatures in stool samples
Description: Stool protein signatures are to be established in parallel to standard clinical evaluation of the intestinal inflammatory activity.

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of protein signatures in stool samples
Description: Stool protein signatures are to be established in parallel to standard clinical evaluation of the intestinal inflammatory activity.
Study: NCT06721988

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: oxycodone and parecoxib sodium combinations
Description: Participants will receive 0.1ml/kg oxycodone (1mg/ml) and 2 ml parecoxib sodium (20 mg/ml) combinations after the anesthesia induction but before the surgical incision. Oxycodone is administered 5 minutes after parecoxib sodium administration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo and parecoxib sodium combinations
Description: Participants will receive 0.1ml/kg placebo (0.9% saline) and 2 ml parecoxib sodium (20 mg/ml) combinations after the anesthesia induction but before the surgical incision. Placebo is administered 5 minutes after parecoxib sodium administration.
Study: NCT06723249

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: stingless bee honey
Description: Participants under intervention group will receive 20g of stingless bee honey in a packet form but participants under control group will not receive any stingless bee honey
Study: NCT06722040

Intervention type: OTHER
Intervention: Implementation of a pediatric triage track
Description: In 2023, a pediatric triage track was implemented at MH1813 to route calls concerning children to specialists in pediatrics, ensuring better expertise.
Study: NCT06722794

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Novel Technique for Fixating the Plate of Ahmed Valve to the Sclera Using a Single Flanged Prolene Suture
Description: This novel technique of fixating the plate of Ahmed glaucoma valve to the sclera using a single flanged prolene suture is an efficient, safe, fast, and reproducible technique that combines the benefits of both fixing the plate providing excellent stability without the complications of free plate techniques and at the same time, minimizing both the risks of conventional old valve plate fixation techniques and the concerns of the relative technical difficulty of suturing due to the difficult access to the posterior globe
Study: NCT06722001

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Brief insomnia intervention interactive e-book
Description: The control group learned through paper health education leaflets and traditional oral explanations; the experimental group used interactive e-books to intervene in learning Brief Behavioral Treatment of Insomnia.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: traditional paper handout
Description: The control group learned through paper health education leaflets and traditional oral explanations; the experimental group used interactive e-books to intervene in learning Brief Behavioral Treatment of Insomnia.
Study: NCT06722144

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal-assisted Therapy
Description: By the professor leader makes social interaction, and helping residents with rehabilitation through the Doctor dogs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal-assisted Therapy
Description: By the professor leader makes social interaction, and helping residents with rehabilitation through the Doctor dogs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal-assisted Therapy
Description: By the professor leader makes social interaction, and helping residents with rehabilitation through the Doctor dogs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal-assisted Therapy
Description: By the professor leader makes social interaction, and helping residents with rehabilitation through the Doctor dogs.
Study: NCT06723730

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Upper Quadrant Core Strengthening protocol
Description: Upper Quadrant Core Strengthening protocol Core strengthening protocol will comprise of following four week protocol.~1. Week one Scapular postural correction and shoulder shrugging exercises~2. Week two External rotation at 0 degree~3. Week three Internal rotation at 0 degree~4. Week four Standing row at 45 and 90 degree , Anterior shoulder stretch and Thoracic exercise in sitting

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Upper Quadrant Core Strengthening protocol
Description: Upper Quadrant Core Strengthening protocol Core strengthening protocol will comprise of following four week protocol.~1. Week one Scapular postural correction and shoulder shrugging exercises~2. Week two External rotation at 0 degree~3. Week three Internal rotation at 0 degree~4. Week four Standing row at 45 and 90 degree , Anterior shoulder stretch and Thoracic exercise in sitting

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mobilization with movement
Description: In addition to upper quadrant core strengthening protocol participants will also perform mobilization with movement.~Mobilization with movement protocol will comprise of following forms.~1. Acromioclavicular joint glides~2. Scapular glides~3. Glenohumeral joint glides ( inferior glides, postero-lateral glides, postero-inferior)
Study: NCT06722313

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Gametes (sperm or second polar bodies, MI eggs) or arrested embryos were reserved for identification of a proband
Description: 1. Targeted deep sequencing for mosaicism detection for patients with suspected gonadal mosaicism, eg. Repeated similar abortion due to the same variant while the couple were tested negative for the variant in the peripheral blood.~2. Ovarian stimulation, embryo culture, biopsy and vitrification as routinely used in the IVF clinical practice.~3. Gametes and arrested embryo preservation by the embryo laboratory during embryo culture.~4. Genetic testing, including multiple displacement amplification for WGA, variant sequencing in WGA products and Infinium Chip protocol for amplified DNA and haplotype analysis
Study: NCT06722014

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STAMP + CBT
Description: A mobile health, smartphone application that provides tailored multi-media, cancer pain psycho-education and self-management advice to participants while facilitating clinician monitoring.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STAMP + CBT
Description: A mobile health, smartphone application that provides tailored multi-media, cancer pain psycho-education and self-management advice to participants while facilitating clinician monitoring.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STAMP + CBT
Description: A mobile health, smartphone application that provides tailored multi-media, cancer pain psycho-education and self-management advice to participants while facilitating clinician monitoring.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Digital Cancer Pain Education Packet
Description: Packet including Articles from the Association for Clinical Oncology and the National Cancer Institute and the pain and medication monitoring form.
Study: NCT06722105

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2 infusions of MSC
Description: 1 MSC(AT) (2x10\^6 cells/kg) injection at M0 and 1 MSC(AT) (2x10\^6 cells/kg) injection at M3

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 1 infusion of MSC
Description: 1 MSC(AT) (2x10\^6 cells/kg) injection at M0 and 1 placebo injection at M3

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo at M0 and M3
Study: NCT06724354

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The Surgical Site Infections Precaution Package Form includes the parameters that should be applied to patients before, during and after surgery.
Description: Surgical site infections are a preventable cause of morbidity following surgical procedures. Strategies to reduce SSI rates should address preoperative, perioperative and postoperative factors, and multiple interventions can be combined into 'bundles'. Adoption of these measures may reduce SSIs, but this is dependent on a high level of package compliance. The aim of this study was to evaluate the change in SSI rates after the implementation of the SSI prevention package after neurosurgical operations. It is thought that if the results of our study are positive, the package form created will be pioneered for use in other patient groups. In addition, reducing SSI rates will shorten the postoperative recovery time of patients and reduce hospital costs.
Study: NCT06219733

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vactosertib
Description: 200 mg PO BID 5 days on / 2 days off

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Imatinib
Description: Imatinib 400 mg PO QD daily
Study: NCT06161766

Intervention type: DRUG
Intervention: terlipressin or noradrenalin plus albumin
Description: Patients with clinical suspicion of HRS-AKI or HRS-AKI-like syndrome in case of previously diagnosed CKD who had received vasoactive treatment for the management of HRS, as defined by the administration of terlipressin or noradrenalin plus albumin.
Study: NCT05869188

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isotretinoin
Description: * Evaluate serum irisin level in acne vulgaris and compare it with healthy control .~* Evaluate the effect of systemic isotretinoin on serum irisin in acne vulgaris patients .

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isotretinoin
Description: * Evaluate serum irisin level in acne vulgaris and compare it with healthy control .~* Evaluate the effect of systemic isotretinoin on serum irisin in acne vulgaris patients .

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isotretinoin
Description: * Evaluate serum irisin level in acne vulgaris and compare it with healthy control .~* Evaluate the effect of systemic isotretinoin on serum irisin in acne vulgaris patients .
Study: NCT06456424

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Phage therapy
Description: Bacteriophage cocktail consisting of phages BP13 and J1P3
Study: NCT04726787

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Bridging Radiotherapy
Description: Bridging Radiotherapy will start immediately after leukapheresis and before Tisagenlecleucel treatment
Study: NCT06063538

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CardiaMend in Combination with Amiodarone
Description: The first three patient will receive 600 mg amiodarone into the intact pericardial space. Amiodarone serum levels will be tested at post operative days 2 and 6. The study will only proceed if there is a serum amiodarone level less than 25% of the normal therapeutic level. This should insure lack of systemic toxicity. After the first 3 patients have demonstrated low amiodarone blood levels, a total of up to 60 patients will be enrolled in the study.~The CardiaMend patch will saturated per the instructions and be sutured into place. Amiodarone will be dripped directly over the heart.
Study: NCT05549804

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KL340399 Intratumoral
Description: KL340399 is a STING-activating. The strength of KL340399 is 0.2 mg/vial or 0.2 mg/vial.
Study: NCT06039449

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VYD222 (pemivibart)
Description: Participants will be dosed on Day 1 followed by redosing at Month 3 (approximately 90 days) with VYD222.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VYD222 (pemivibart)
Description: Participants will be dosed on Day 1 followed by redosing at Month 3 (approximately 90 days) with VYD222.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Participants will be dosed on Day 1 followed by redosing at Month 3 (approximately 90 days) with Placebo.
Study: NCT04321525

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive-behavioral therapy
Description: 10 individual one-hour sessions, with one or two booster sessions at about three months after the tenth session

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personal Construct Therapy
Description: 10 individual one-hour sessions, with one or two booster sessions at about three months after the tenth session

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personal Construct Therapy with virtual reality
Description: 10 individual one-hour sessions, with one or two booster sessions at about three months after the tenth session
Study: NCT05257876

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing exercise
Description: Participants will receive breathing exercise training, and a 4-week self exercise
Study: NCT06096532

Intervention type: OTHER
Group type: OTHER
Intervention: 75 gm oral glucose load
Description: Consumption of 75 gm oral glucose load in order to test nutrient responsiveness

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 75 gm oral glucose load
Description: Consumption of 75 gm oral glucose load in order to test nutrient responsiveness
Study: NCT05840458

Intervention type: PROCEDURE
Intervention: PENG Block
Description: Patient will be placed in the supine position and the ultrasound probe will be placed in the transverse plane over the anterior inferior iliac spine (AIIS) and aligned with the pubic ramus by rotating the probe counterclockwise by approximately 45 degrees. A 22-gauge, 100 mm needle will be inserted using the plane approach from lateral to medial, between the psoas tendon anteriorly and the pubic ramus posteriorly. Following a negative aspiration, 20 mL of 0.375% ropivacaine will be injected. The needle position will be confirmed by visualizing the separation of layers with the dispersion of the injected volume.
Study: NCT05748145

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metronidazole Oral
Description: Metronidazole will be administered per os at 500 mg x 3/day, for 10 days prior to surgery.
Study: NCT06023472

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: microfluidic chip
Description: Microfluidic chip method has been used for sperm sorting in order to select the most motile and morphologically normal sperm for use in assisted reproductive technologies (ART) such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
Study: NCT03003195

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: P10s-PADRE
Description: All research participants will receive the Mimotope P10s-PADRE/MONTANIDE ISA 51 VG vaccine via subcutaneous (SC) injection for a total of 4 vaccinations.
Study: NCT06455215

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Community garden activities
Description: The gardens in the intervention group will receive an 8-week intervention that includes 1) educational materials, 2) healthy cooking demonstrations, food and transportation support and 3) garden social activities. The control group will be asked to abstain from intervention activities. The control group will receive the delayed 8-week intervention one year after the intervention group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community garden activities
Description: The gardens in the intervention group will receive an 8-week intervention that includes 1) educational materials, 2) healthy cooking demonstrations, food and transportation support and 3) garden social activities. The control group will be asked to abstain from intervention activities. The control group will receive the delayed 8-week intervention one year after the intervention group.
Study: NCT06048952

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Music Therapy
Description: Huseyni maqam, Pentatonic music
Study: NCT05536063

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: bilateral erector spinae plane block in pediatric cardiac surgeries
Description: The ESPB will be performed after induction of anesthesia, endotracheal tube insertion and before the start of operation, with the child in a right lateral decubitus position under aseptic precautions. A high frequency linear ultrasound transducer will be placed over the T4 transverse process lateral to the spinous process. After identifying the muscles above the hyperechoic transverse process image, a 5-cm 22 gauge needle will be inserted in-plane in a cephalo-caudad direction. The endpoint is defined as the needle pointing to the tip of transverse process piercing the erector spinae muscle. The local anesthetic will be deposited at this position, After careful negative aspiration, local anesthetic, according to study groups , The process will be repeated on thecontralateral side

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: bilateral erector spinae plane block in pediatric cardiac surgeries
Description: The ESPB will be performed after induction of anesthesia, endotracheal tube insertion and before the start of operation, with the child in a right lateral decubitus position under aseptic precautions. A high frequency linear ultrasound transducer will be placed over the T4 transverse process lateral to the spinous process. After identifying the muscles above the hyperechoic transverse process image, a 5-cm 22 gauge needle will be inserted in-plane in a cephalo-caudad direction. The endpoint is defined as the needle pointing to the tip of transverse process piercing the erector spinae muscle. The local anesthetic will be deposited at this position, After careful negative aspiration, local anesthetic, according to study groups , The process will be repeated on thecontralateral side