TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04716426

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tetracycline hydrochloride 3%
Description: Proprietary formulation composed of FDA approved inactive ingredients and the active pharmaceutical ingredient tetracycline hydrochloride.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Formulation composed of FDA approved inactive ingredients.
Study: NCT06527339

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling with Vibration
Description: In the PS+V technique, no movements will be performed with the needle once it is correctly inserted. Instead, only vibratory stimulus will be applied for 10 minutes. Since this is a completely novel technique, the optimal duration of application is not yet known; however, it is considered that 10 minutes may be sufficient to demonstrate an effect.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Dry Needling
Description: In the conventional PS technique, the needle will be inserted into the MTrP using the fast-in and fast-out technique described by Hong (1994) at an approximate frequency of 1 insertion per second (1 Hz) without completely withdrawing the needle from the skin. This technique will be maintained for 30 seconds in an attempt to elicit a local twitch response. After the procedure, the treated area will be firmly compressed with a cotton pad for three seconds.
Study: NCT04944459

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Muse-S headband; InteraXon Inc., RRID:SCR_014418
Description: Muse-S is used as a technology-supported Mindfulness Training (tsMT) device as a way to introduce meditation as a method for managing chronic pain in individuals as it facilitates the learning process, requires minimal training to use and provides mechanisms to enhance compliance and track progress. The availability of direct feedback data from Muse-S may encourage the participant to perform meditation sessions and may increase time spent in the calm brain state.
Study: NCT04933773

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Movement artifact - knocking
Description: 60 seconds motion artifact simulation - knocking with sensors

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Movement artifact - tremor
Description: 60 seconds motion artifact simulation - tremor with sensors
Study: NCT06150950

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cardiac rehabilitation
Description: Cardiac rehabilitation is a multifaceted, comprehensive therapeutic intervention of personalized, supervised exercise training that is beneficial and well-studied among patients with non-ACHD heart failure and has consistently been shown to improve QOL. Unfortunately, cardiac rehabilitation has been underutilized with an overall participation \<50% of eligible patients despite international guidelines advocating for more consistent deployment of cardiac rehabilitation. A major a barrier to cardiac rehabilitation is access, as CMS-mandates a physician be within 3 minutes of the rehabilitation facility to assure insurance reimbursement. This mandate limits isolated, outpatient cardiac rehabilitation programs, especially in rural communities.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: For participants randomized to the usual care (no cardiac rehabilitation group), cardiac rehabilitation will not be initiated between randomization and for up to 16 weeks following randomization. The study protocol controls only referral to cardiac rehabilitation. All other aspects of the cardiac care, such as titration of guideline directed medical therapy will be at the discretion of clinicians.
Study: NCT04933773

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Movement artifact - tremor
Description: 60 seconds motion artifact simulation - tremor with sensors

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artifact - ambient light
Description: 60 seconds artifact simulation - ambient light using sensor opening

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artifact - ambient light
Description: 60 seconds artifact simulation - ambient light using sensor opening

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artifact - low perfusion
Description: 60 seconds artifact simulation - reduced perfusion using a cuff

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artifact - low perfusion
Description: 60 seconds artifact simulation - reduced perfusion using a cuff

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SpO2 measurement
Description: Two SpO2 measuring devices are active simultaneously on one hand during measurement.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SpO2 measurement
Description: Two SpO2 measuring devices are active simultaneously on one hand during measurement.
Study: NCT05010837

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesio taping with abdominal exercises
Description: Experimental group was given kinesio taping along with abdominal exercises. Kinesio taping was applied in I-band technique. the first band is applied on rectus abdominis from origin to insertion starting from pubic symphysis till the xiphoid process. the second band is applied bilaterally on the left and right side external oblique muscles.~Abdominal exercises consist of 2-3 sets of 8 to 12 repetitions of head lift with bracing, head lift with pelvic tilt, pelvic clock, bridging, knee rolling and deep breathing exercises for 1 to 4 weeks.~From 5 to 8 weeks Same abdominal exercises with 5 sets and 15 to 20 repetitions were performed along with kinesio taping.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Abdominal exercises
Description: Abdominal exercises consist of 2-3 sets of 8 to 12 repetitions of head lift with bracing, head lift with pelvic tilt, pelvic clock, bridging, knee rolling and deep breathing exercises for 1 to 4 weeks.~From 5 to 8 weeks Same abdominal exercises with 5 sets and 15 to 20 repetitions were performed.
Study: NCT05002829

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Restricted Duration of SOC Antibiotic Use
Description: Standard of Care Antibiotic use will be restricted to none or up to 24 hours of post-operative antibiotics.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Liberal Duration of SOC Antibiotic Use
Description: Standard of Care Antibiotic use will be permitted for 24 hours or up to 4 days of post-operative antibiotics.
Study: NCT05028192

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT05620316

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BOTOX® Injection
Description: 100 MU of botulinum toxin type A (BOTOX® - Allergan Inc. - Dublin - Ireland) were diluted in 2ml of saline. Patients were injected with 10 MU of BTXA per side at two sites into the masseter muscle bilaterally. The first site was the inferior prominent part of the masseter muscle observed when the subject was asked to clench, and the other site was 5 mm below the first point

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Prick skin
Description: patients were pricked twice at the inferior prominent part of the masseter muscle observed using the stinger pen used in the blood glucose meter; it is less painful and provides psychological benefits, instead of injecting the physiological saline into the muscle to avoid the severe pain without a benefit to the patient which would not conform to the ethical standards.
Study: NCT04924335

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector spinae plane block
Description: Preoperative ultrasound-guided bilateral erector spinae plane block with 20 ml 0.025% bupivacaine.
Study: NCT05239481

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: colonoscopy position identification sheet
Description: According to the body position requirements of the left lying position during colonoscopy, the research group used ink to add the body position prompt sign on the disposable bed sheet .Through the position identification, patients can intuitively understand the position that should be used in the operation and the position that should be placed in each part of the body.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Traditional disposable cleaning sheet
Description: Traditional disposable cleaning sheets were used during control colonoscopy.Before the examination, the nursing staff took a unified and simple language to guide the patient.
Study: NCT05384340

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beetroot juice rich in nitrate
Description: On the first day, an acute test will be carried out with beet juice rich in nitrate, in which two units of juice will be provided, totaling 140 ml (800 mg of nitrate) for each protocol. That is, each participant will receive 2 units of juice bottles. From the second to the seventh day, participants will receive 6 units of vials of the juice corresponding to the first intervention on the first visit to the laboratory and will drink one vial a day for a week. Of the 8 units (100%), six bottles (75%) will be provided for the participants to take home. On the seventh day of the intervention, the participants will return to the laboratory for the consumption of the seventh and last bottle of juice. Between one protocol and another, a 7-day washout interval will be given for the purification of the compounds provided by the protocols.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Beetroot juice rich in nitrate
Description: On the first day, an acute test will be carried out with beet juice rich in nitrate, in which two units of juice will be provided, totaling 140 ml (800 mg of nitrate) for each protocol. That is, each participant will receive 2 units of juice bottles. From the second to the seventh day, participants will receive 6 units of vials of the juice corresponding to the first intervention on the first visit to the laboratory and will drink one vial a day for a week. Of the 8 units (100%), six bottles (75%) will be provided for the participants to take home. On the seventh day of the intervention, the participants will return to the laboratory for the consumption of the seventh and last bottle of juice. Between one protocol and another, a 7-day washout interval will be given for the purification of the compounds provided by the protocols.
Study: NCT05672290

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrical stimulation 1
Description: External electrical stimulation will be applied for 30 minutes 3 days a week during 6 weeks. Electrodes were placed around the pelvis.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrical stimulation 2
Description: External electrical stimulation will be applied for 30 minutes one day a week during 6 weeks. Electrodes were placed around the pelvis.
Study: NCT05452889

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-FGLN PET Imaging
Description: PET/CT Imaging: The duration of PET will be around 90 minutes. Women should have negative pregnancy test prior to the study. An arterial line will be placed in the radial artery for arterial blood sampling and this will be performed by an experienced anesthesiologist. An intravenous catheter will be placed in the subject's opposite arm, which will be used for radiotracer administration. A low-dose helical CT scan will be performed during a \~15 sec inspiratory breath hold and used for CT-based attenuation correction of PET emission data and as an anatomical reference for image analyses. Blood Sampling: For the PET scan, the amount of blood will not be more than 43 arterial samples and a blood volume loss of no more than 60 ml (4-5 tablespoonfuls). Participants will be retained in the PET facility following the PET scan to evaluate for bleeding from the arterial puncture site and/or to promote urination to increase elimination of the radiotracer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: (18F)FPGLU
Description: \[F-18\]FGln is a natural glutamine derivative was synthesized to explore its potential application of imaging glutamine uptake for cancer diagnosis. The proposed research study will provide preliminary evidence of the potential to utilize \[F-18\]FGln as a non-invasive imaging biomarker of glutamine flux and metabolism across a range of PAH subjects.
Study: NCT06304116

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Rehabilitation therapy
Description: During the treatment, All the participants were provided with the rehabilitation therapy, which included routine rehabilitation, cognitive training, swallowing function training and nutrition support.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: During the treatment, All the participants were provided with the rehabilitation therapy, which included routine rehabilitation, cognitive training, swallowing function training and nutrition support.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Stellate ganglion block
Description: The percutaneous approach via the paratracheal route was used for Stellate ganglion block . The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: The percutaneous approach via the paratracheal route was used for Stellate ganglion block . The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine Hydrochloride
Description: Based on the invention above, the patients in the observation group were provided with Stellate ganglion block , using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g). The percutaneous approach via the paratracheal route was used for Stellate ganglion block . The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.
Study: NCT06389630

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: video-assisted training group
Description: This group will be taught subcutaneous insulin injection through video-supported training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: low fidelity simulation model group
Description: This group will be taught subcutaneous insulin injection on a low-fidelity simulation model.
Study: NCT04818658

Intervention type: OTHER
Intervention: Assessment of the stainless steel crown using the Hall Technique and Compomer Restoration on primary molars
Description: Intra-oral clinical examination is performed and restorations are evaluated by the practitioner. Periapical radiography is taken according to national guidelines.

Intervention type: OTHER
Intervention: Assessment of the stainless steel crown using the Hall Technique and Compomer Restoration on primary molars
Description: Intra-oral clinical examination is performed and restorations are evaluated by the practitioner. Periapical radiography is taken according to national guidelines.
Study: NCT05339360

Intervention type: PROCEDURE
Intervention: Femoral fixation with intramedullary nails
Description: Femoral fracture fixation Femoral Osteotomy
Study: NCT05515731

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous platelet-rich plasma (PRP) eye drops
Description: Autologous platelet-rich plasma (PRP) eye drops are used as a sole or adjunctive therapy in many ophthalmological conditions including dry eye, macular holes, retinitis pigmentosa and perforated corneal ulcers. Actions of PRP in these conditions are attributed to the plethora of growth and healing factors concentrated in different PRP preparations.
Study: NCT05150184

Intervention type: OTHER
Intervention: Non-interventional
Description: observational study, thus no different arm/groups
Study: NCT04604145

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen
Description: Obtain self-collected saliva sample, perform SARS-CoV-2 testing using the Eppendorf Thermal Cycler Polymerase chain reaction (PCR) system on 30 samples associated with a positive and 30 samples associated with a negative NP sample, then compare saliva results to healthcare worker collected NP sample results evaluated on either the BioFire® FilmArray® Torch® system or the Cepheid® GeneXpert® (gold standard).

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen
Description: Obtain self-collected saliva sample, perform SARS-CoV-2 testing using the Eppendorf Thermal Cycler Polymerase chain reaction (PCR) system on 30 samples associated with a positive and 30 samples associated with a negative NP sample, then compare saliva results to healthcare worker collected NP sample results evaluated on either the BioFire® FilmArray® Torch® system or the Cepheid® GeneXpert® (gold standard).
Study: NCT05724732

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GT201
Description: Autologous tumor infiltrating lymphocyte injection
Study: NCT06214975

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EXOPULSE Mollii Suit Stimulation
Description: We designed a randomized crossover, sham-controlled, double-blind trial to demonstrate the improvement of motor functions and stroke related symptoms following a single session of active versus sham EXOPULSE Mollii suit stimulation. in phase 1, the patient will receive two stimulations separated by a two-week washout period. The patients will be randomized to receive either active/sham or sham/active and both patients and investigators will be blinded to the order in which the stimulation will be given. A 2-week washout period should be enough to prevent a potential carry over effect. Two weeks after the end of phase 1, a second open label phase (phase 2) of this trial will be proposed to all patients where they will receive active stimulation every other day at home over four weeks (for a total of 14 sessions). This will help understand the long term effects of EXOPULSE Mollii suit stimulation on stroke related symptoms.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: EXOPULSE Mollii Suit Stimulation
Description: We designed a randomized crossover, sham-controlled, double-blind trial to demonstrate the improvement of motor functions and stroke related symptoms following a single session of active versus sham EXOPULSE Mollii suit stimulation. in phase 1, the patient will receive two stimulations separated by a two-week washout period. The patients will be randomized to receive either active/sham or sham/active and both patients and investigators will be blinded to the order in which the stimulation will be given. A 2-week washout period should be enough to prevent a potential carry over effect. Two weeks after the end of phase 1, a second open label phase (phase 2) of this trial will be proposed to all patients where they will receive active stimulation every other day at home over four weeks (for a total of 14 sessions). This will help understand the long term effects of EXOPULSE Mollii suit stimulation on stroke related symptoms.
Study: NCT06352580

Intervention type: OTHER
Intervention: Survey
Description: 26 survey questions were administered face to face to parents, which they could answer in a short time.
Study: NCT04834817

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Celluma POD
Description: A blue and near infrared handheld LED device
Study: NCT05004571

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EQU-001
Description: EQU-001 in 10 and 20 mg capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo