TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05142397

Intervention type: PROCEDURE
Intervention: Focused Ultrasound
Description: Focused ultrasound generates heat effects, mechanical effects and cavitation effects that denature the diseased tissues, facilitate necrosis and allow them to be replaced by surrounding normal healthy tissues.
Study: NCT05734612

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine
Description: Patients in the intervention group receive loading dose of colchicine 1 x 2 mg followed by colchicine 2 x 0,5 mg daily for two consecutive days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (lactose)
Description: Patients in the control group receive loading dose of placebo (lactose) 1 x 2 mg followed by lactose 2 x 0,5 mg daily for two consecutive days.
Study: NCT06447194

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail
Description: Please refer to description for interventional group.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 100mL paraspinal normal saline injection intraoperatively, once.
Study: NCT05622240

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99mTc-MIRC213
Description: 99mTc-MIRC213 were intravenous injected into the patients before the wholebody and SPECT/CT scans

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99mTc-MIRC213
Description: 99mTc-MIRC213 were intravenous injected into the patients before the wholebody and SPECT/CT scans
Study: NCT05776719

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health & Wellness
Description: PowerPoint slide decks will be shown via shared screen. The wellness group will be largely educational in nature and will encourage discussion, setting goals, and making healthy choices. Similar topics covered in this group have been used previously in health promotion classes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Warrior Renew
Description: The group format includes warm-up community building exercises, psychoeducational presentation of material standardized by the use of PowerPoint slides, followed by discussion of the information and interactive exercises, and closes with exercises to improve affect management skills, such as mindfulness or guided imagery.
Study: NCT04875936

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motor Imagery and Real-Time fMRI Neurofeedback
Description: Survivors of left-hemisphere stroke (\<10 weeks post-stroke) or healthy volunteers will use right-hand motor imagery coupled with fMRI neurofeedback to help them re-engage the left hemisphere by shifting brain activation leftward relative to the initial left-right asymmetry. Following group assignment, participants will perform a motor imagery task and complete 3 sessions of motor imagery and reading tasks in the MRI scanner over 3 weeks. During the MRI sessions they will receive real time neurofeedback about how well they are engaging the left side of their brain compared to the right side. They will also practice the same task for 30 min a day as homework using the most effective motor imagery strategy that worked for them in the MRI scanner.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Motor Imagery and Sham fMRI Neurofeedback
Description: Survivors of left-hemisphere stroke (\<10 weeks post-stroke) or healthy volunteers will practice right-hand motor imagery coupled with sham fMRI neurofeedback. As the experimental group, participants will perform a motor imagery task and complete 3 sessions of motor imagery and reading tasks in the MRI scanner over 3 weeks. However, during the MRI sessions they will receive sham neurofeedback on the basis of another participant's brain activity. Like the experimental group, they will also practice the same task for 30 min a day as homework.
Study: NCT05347446

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hybrid ESD
Description: Method of removing colon lesion

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-hybrid ESD
Description: Method of removing colon lesion
Study: NCT06599840

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Parent intervention
Description: This is a novel intervention based on established CBT-based parenting strategies that are regularly used to strengthen parent-child cooperation and reduce conflicts. Here, the strategies are adapted to address typical challenges of T1D family life. The program structure consists of six weekly modules and a seventh booster module. Each of the first six modules has a theme with information on a parental strategy associated with the theme, self-reflective questions, and an assignment where parents plan to implement the strategy during the upcoming week. One month later, a seventh session is held to summarize the program and make plans for future progress.
Study: NCT06587737

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine 0.5 MG
Description: colchicine 0.5mg once-daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: matching placebo, lacking active ingredient, once-daily
Study: NCT05062213

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moisturizer Body Lotion
Description: Moisturizer Body Lotion
Study: NCT06600022

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SCTB41
Description: SCTB41 of different doses,IV,every 3 weeks
Study: NCT06680232

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PBGENE-HBV
Description: PBGENE-HBV is an in vivo gene editing intervention based on a novel proprietary ARCUS® platform designed to potentially cure chronic hepatitis B virus (HBV) by eliminating cccDNA, the key source of replicating hepatitis B virus, while also inactivating integrated HBV DNA in hepatocytes.
Study: NCT06680427

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Siegel Transcatheter Aortic Valve (TAVR)
Description: Replacement of native aortic valve with the Siegel Transcatheter Aortic Valve (TAVR) by a transfemoral approach.
Study: NCT04616560

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo echocardiography

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multigated Acquisition Scan
Description: Undergo MUGA

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Trastuzumab Deruxtecan
Description: Given IV
Study: NCT06624644

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LNS8801
Description: G protein-coupled estrogen receptor (GPER) agonist

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LNS8801
Description: G protein-coupled estrogen receptor (GPER) agonist

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Recombinant monoclonal antibody (anti-PD1)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy (dacarbazine or temozolomide)
Description: chemotherapy (dacarbazine, temozolomide)

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Immunotherapy (Pembrolizumab)
Description: pembrolizumab

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Immunotherapy (nivolumab and relatlimab)
Description: nivolumab and relatlimab

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Immunotherapy (ipilimumab and nivolumab)
Description: ipilimumab and nivolumab
Study: NCT06629831

Intervention type: OTHER
Intervention: group with complications
Description: Complications in patients undergoing cytoreduction surgery for ovarian cancer

Intervention type: OTHER
Intervention: group without complications
Description: Complications in patients undergoing cytoreduction surgery for ovarian cancer
Study: NCT06629844

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The VR dementia education group
Description: The intervention group will receive the VR dementia education program, which will be conducted once for each participant, and each session will accommodate a maximum of 20 participants. The VR dementia education program will follow the flow below, integrating video dramatizations, VR experiences, lectures, and discussions. The program is designed to simulate real-life dementia care situations, encourage reflection, and enhance nursing students' understanding of dementia management. The following are the steps for intervention: Introduction (3 minutes), Pre-Program Questionnaire (10 minutes), Lecture Introduction (2 minutes), Bad Drama (Unfriendly Communication) (10 minutes), Bad VR (10 minutes), Discussion (5 minutes), Lecture 1: What is Dementia? (10 minutes), Good VR (10 minutes), Good Drama (10 minutes), Lecture 2: What Can We Do to Support PLWD? (5 minutes), N-impro (10 minutes), Post-Program Questionnaire (10 minutes), Conclusion (5 minutes).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The control group
Description: The intervention begins with an introduction to the VR dementia program, outlining its objectives and setting participant expectations. A pre-program questionnaire follows to assess baseline knowledge, attitudes, and intention to assist people with dementia. A brief lecture introduces a dramatization showing ineffective communication with a PLWD, followed by a VR scenario highlighting poor care practices. After discussing these observations, participants attend a lecture explaining dementia's symptoms and progression, with culturally adapted video content for Indonesian audiences. Next, a positive VR scenario demonstrates best practices in dementia care, followed by a video on supportive communication. A second lecture offers practical strategies for caregiving and communication, complemented by an N-impro session to deepen understanding. The session concludes with a post-program questionnaire and final reflection to encourage real-world application of the learned skills.
Study: NCT06634316

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mediterranean diet
Description: Mediterranean diet recommendations and daily physical exercise

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: Mediterranean diet recommendations and daily physical exercise

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: Mediterranean diet recommendations and daily physical exercise

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hypercaloric, hyperproteic oral nutritional supplement
Description: Hypercaloric, hyperproteic oral supplement combined with Mediterranean diet recommendations (2 per day) and daily physical exercise

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein module
Description: Protein module (10g/day) combined with Mediterranean diet recommendations and daily physical exercise

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D supplementation
Description: Calcifediol supplement administered orally in order to reach sufficiency levels (30 ng/ml)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Vitamin D supplementation
Description: Calcifediol supplement administered orally in order to reach sufficiency levels (30 ng/ml)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Vitamin D supplementation
Description: Calcifediol supplement administered orally in order to reach sufficiency levels (30 ng/ml)

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Physical exercise
Description: Physical exercise adapted to patients with heart failure (Cardiac rehabilitation)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: Physical exercise adapted to patients with heart failure (Cardiac rehabilitation)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: Physical exercise adapted to patients with heart failure (Cardiac rehabilitation)
Study: NCT06633861

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: spot-check measurement
Description: Spot-check measurement: different Philips SpO2 sensors and Philips FAST pulse oximeter system, capnography
Study: NCT06633952

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MediTrain
Description: MediTrain is a tablet-based, meditation-inspired, cognitive training game aimed at improving self-regulation of internal attention and distractions. It was developed in collaboration with meditation thought-leader Jack Kornfield, and Zynga, a world-class video game company. It was created to make benefits of concentrative meditation more easily accessible to anyone, including complete novices. This is achieved by creating a game that yields quantifiable and attainable goals, provides feedback, and includes an adaptive algorithm to gradually increase difficulty as users improve.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Worder
Description: Worder was designed to enhance visual motor and visual spatial skills in individuals of all ages and cognitive abilities. Visual processing is required for all cognitive abilities that involve vision including attention, working memory, and task management. Worder's goal is to improve cognitive function more broadly by developing this critical skill underlying multiple abilities.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: noninvasive neurostimulation device
Description: A noninvasive neurostimulation device will be used to deliver theta frequency stimulation or sham stimulation to the frontal part of the brain.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: noninvasive neurostimulation device
Description: A noninvasive neurostimulation device will be used to deliver theta frequency stimulation or sham stimulation to the frontal part of the brain.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wrist worn multi-sensor watches
Description: Stress and sleep data will be recorded at home throughout the intervention using FDA-approved wrist worn multi-sensor watches.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wrist worn multi-sensor watches
Description: Stress and sleep data will be recorded at home throughout the intervention using FDA-approved wrist worn multi-sensor watches.
Study: NCT06633185

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: phenytoin cream
Description: application of the cream after internal anal sphincterotomy versus non application.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: no phenytoin cream
Description: Non application of the phenytoin cream
Study: NCT06634147

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Multicomponent individualized exercise intervention As mentioned earlier, patients in the control group (G0) will receive the usual care currently provided to other patients, which includes a referral to physical therapy if needed.~The intervention for the multicomponent physical exercise intervention group (G1) will consist of a multicomponent physical training program that includes progressive and supervised aerobic endurance, strength, and balance training lasting 4-7 days during their hospitalization. This will be supervised by the research team from the Geriatrics Unit. Additionally, after hospital discharge, they will receive individualized guidelines to engage in multicomponent physical exercise for 3 months, along with individualized recommendations from the Nutrition and Dietetics Service of HUN.~The multicomponent physical training program will consist of chair squat exercises. The main part of the training will utilize machines for strength training for the lower extremit
Study: NCT05997095

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromuscular electrical stimulation (NMES/0
Description: NMES will be applied for 30 min and will be delivered using an approved, CE-marked device (Premier Combo Plus, Med-Fit Ltd, UK) using two large (7.5 × 13 cm) electrodes placed proximally and distally over the lateral quadriceps. The set protocols will be pre-programmed into to the device and the amplitude value will match the setting that was determined during a familiarisation visit

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neuromuscular electrical stimulation (NMES/0
Description: NMES will be applied for 30 min and will be delivered using an approved, CE-marked device (Premier Combo Plus, Med-Fit Ltd, UK) using two large (7.5 × 13 cm) electrodes placed proximally and distally over the lateral quadriceps. The set protocols will be pre-programmed into to the device and the amplitude value will match the setting that was determined during a familiarisation visit

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromuscular electrical stimulation (NMES/0
Description: NMES will be applied for 30 min and will be delivered using an approved, CE-marked device (Premier Combo Plus, Med-Fit Ltd, UK) using two large (7.5 × 13 cm) electrodes placed proximally and distally over the lateral quadriceps. The set protocols will be pre-programmed into to the device and the amplitude value will match the setting that was determined during a familiarisation visit
Study: NCT05350605

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding position education with lactation simulation model
Description: pregnant women will receive training with a lactation simulation model once in the last trimester.The pregnant woman will wear the lactation simulation model during the education period and show what she has learned practically on the model.Mothers who have given birth will be supported to practice the breastfeeding position in the postpartum service.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding position education with lactation simulation model
Description: pregnant women will receive training with a lactation simulation model once in the last trimester.The pregnant woman will wear the lactation simulation model during the education period and show what she has learned practically on the model.Mothers who have given birth will be supported to practice the breastfeeding position in the postpartum service.
Study: NCT06736730

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hospital-Linked Violence Intervention Program
Description: Activation of Operation Good, our community partner with a history of direct violence interruption in the streets and longitudinal health and wellness services to firearm injured patient (i.e. linking and aiding those who have suffered from violent injury to mental healthcare, job services, educational services)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Community Event Support
Description: A menu of services provided to the community in an activated cluster where funding will be provided to assist that community in holding events that support overall health and wellness (community clean-up, legal advisory services, pop-up clinic for blood pressure checks).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Unrestricted Cash Assistance
Description: A participant in an activated cluster after firearm injury will receive two disbursements of 500$. One at the time of initial hospital evaluation and a second disbursement \~1 month later to offset the financial burden associated with firearm injury on the individual.
Study: NCT06776809

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music listening
Description: Selection of Sufi music will be played to the patients during the course of the operation.
Study: NCT06775314

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cleanser
Description: Cleanser consist of Triethyl citrate and Pyruvic acid, will be given to subjects to be applied every morning, evening and night in group 2

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Combination cream
Description: combination cream consist of Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic acid will be given to subjects to be applied every morning, evening and night in group 2

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: spot cream
Description: spot cream consist of Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol, will be given to subjects to be applied every morning and evening in group 2

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Adapalene 0,1% cream
Description: adapalene 0.1% cream will be given to subjects to be applied every night in group 1 and 2

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adapalene 0,1% cream
Description: adapalene 0.1% cream will be given to subjects to be applied every night in group 1 and 2

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo cleanser
Description: placebo cleanser will be given to subjects to be applied every morning, evening and night in group 1
Study: NCT06045767

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab 50 MG Injection [Keytruda]
Description: Chemo-immunotherapy combination
Study: NCT05687812

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Cephalaria Syriaca flour-added bread
Description: 100g of test bread (consisting of 0.2% Cephalaria Syriaca flour bread) containing 50g of carbohydrates (KH).

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Cephalaria Syriaca flour-added bread
Description: 100g of test bread (consisting of 0.2% Cephalaria Syriaca flour bread) containing 50g of carbohydrates (KH).

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Cephalaria Syriaca flour-added bread
Description: 100g of test bread (consisting of 0.2% Cephalaria Syriaca flour bread) containing 50g of carbohydrates (KH).
Study: NCT06495229

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CM310
Description: IL-4Rα monoclonal antibody
Study: NCT06245057

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maternity care home model (MCHM)
Description: The maternity care home model is defined as office based prenatal care integrated with comprehensive social services.
Study: NCT05713721

Intervention type: OTHER
Intervention: 24 hours drug withdrawal of dopaminergic medication
Description: Examinations will be done under chronic dopaminergic treatment and after a 24 hours dopaminergic drug withdrawal.

Intervention type: OTHER
Intervention: Evaluation of deep brain stimulation
Description: Examinations will be done before and after implantation of deep brain stimulation (clinically optimal stimulation vs. switched off stimulation)
Study: NCT04981743

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nigella Sativa capsule twice daily
Description: investigate the safety and efficacy of Nigella Sativa versus Vitamin D3 versus Nigella Sativa / vitamin D3 combination as supplement for management of COVID-19 .

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nigella Sativa capsule twice daily
Description: investigate the safety and efficacy of Nigella Sativa versus Vitamin D3 versus Nigella Sativa / vitamin D3 combination as supplement for management of COVID-19 .

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nigella Sativa capsule twice daily
Description: investigate the safety and efficacy of Nigella Sativa versus Vitamin D3 versus Nigella Sativa / vitamin D3 combination as supplement for management of COVID-19 .