TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06740903

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h
Description: Anesthesia induction will be done by doing pre-oxygenation for 3 minutes with 100% oxygen, propofol 2-2.5 mg/kg intravenous (IV) and nalbuphine 0.1mg/kg intravenous (IV). Tracheal intubation will be facilitated by succinylcholine 1.5 mg/kg IV. Anaesthesia will be maintained with isoflurane 0.6 mac, 60% nitrous oxide, 40% oxygen, atracurium 0.5mg/kg bolus followed by 0.15mg/kg maintenance dose every 30 mints until completion of surgery. Patients Intraoperative monitoring will include electrocardiogram leads II and V5, non-invasive blood pressure at 5 min intervals, oxygen saturation, end-tidal carbon dioxide and nasopharyngeal temperature. Patients will be ventilated by intermittent positive pressure ventilation using a circle system to maintain normocapnia. In group A, patients will be given inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h intraoperatively

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: inj. lignocaine infusion @1-2 mg/kg/h
Description: Anesthesia induction will be done by doing pre-oxygenation for 3 minutes with 100% oxygen, propofol 2-2.5 mg/kg intravenous (IV) and nalbuphine 0.1mg/kg intravenous (IV). Tracheal intubation will be facilitated by succinylcholine 1.5 mg/kg IV. Anaesthesia will be maintained with isoflurane 0.6 mac, 60% nitrous oxide, 40% oxygen, atracurium 0.5mg/kg bolus followed by 0.15mg/kg maintenance dose every 30 mints until completion of surgery. Patients Intraoperative monitoring will include electrocardiogram leads II and V5, non-invasive blood pressure at 5 min intervals, oxygen saturation, end-tidal carbon dioxide and nasopharyngeal temperature. Patients will be ventilated by intermittent positive pressure ventilation using a circle system to maintain normocapnia. In group A, patients will be given inj. lignocaine infusion @ 1-2 mg/kg/h intraoperatively
Study: NCT06739824

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Conventional Treatment(CI)
Description: Patients receive a corticosteroid injection followed by conventional treatment, such as standard physical therapy exercises focused on range of motion and strengthening, without the specific manual techniques of the Spencer method.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Spencer Technique (CI)
Description: Patients receive a corticosteroid injection followed by the Spencer technique, which involves a series of specific manual mobilization maneuvers aimed at improving shoulder mobility and reducing pain.
Study: NCT06737978

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AngioSafe Peripheral-5 CTO Crossing System
Description: AngioSafe Peripheral-5 CTO Crossing System is used to help the doctor to pass a guidewire through the blockage in blood vessels below the knee.
Study: NCT06741280

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Profilm Aftas Bucales
Description: The treatment will consist of daily applications of the product as soon as an oral ulcer appears, until its complete disappearance or healing, as follows: application every 8 hours, with the possibility of shortening the interval to 6 hours if needed (a maximum of 3-4 applications).
Study: NCT06739590

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Learning with CT scans
Description: The average performance improvement in this group will serve as the baseline for learning achievable through conventional CT and MR imaging alone.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning with 3D visualization models
Description: Learning anatomical structures using three-dimensional visualization models displayed on a computer.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Learning with 3D-MR visualization models
Description: Viewing and manipulating 3D visualization models to learn anatomical structures using the MR headset.
Study: NCT06738433

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ABB i5
Description: Prebiotic ABB i5 (NextDext®, 5g)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ABB C24
Description: ABB C24: Prebiotic ABB i5 (NextDext®, 5g) + yeast postbiotic ABB C22 (200 mg) in sachets containing 5,2 g
Study: NCT06738953

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Intervention to increase Self Efficacy
Description: Participants in the intervention group will receive a brief (6 sessions of 75-90 min each) cognitive-behavioral intervention. The intervention will be delivered in an online group format (subgroups of 8-12 participants). The courses will be structured according to well-established self-efficacy interventions with proven effectiveness (Bresó et al., 2011; Cieslak et al., 2016; Luszczynska et al., 2007), targeting Bandura's four key sources of self-efficacy (i.e., mastery experience, vicarious experience, verbal persuasion, and physiological/emotional arousal). Each session will consist of a theoretical and a practical part and be structured as follows: opening, discussion of homework (with special emphasis on participants' progress and sharing of experiences), introduction to the topic, practice, answering open questions, closing. The course sessions are accompanied by weekly homework assignments to be completed at home.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo: Weekly Recap and Group Discussion on Psychological Experiments
Description: Participants in the control group will meet in small groups (8-12 participants per group; 6 sessions, similar to the intervention group). They will receive a brief introduction to well-known psychological experiments and findings (e.g., the Asch experiment, selective attention) and discuss their perspectives on these topics, including personal implications of the experiments. Content related to self-efficacy or cognitive-behavioral interventions will be explicitly avoided. To prevent expectancy effects and other biases, participants will not be informed that they are part of the control group. If suspicions arise, participants will be told that group leaders are not allowed to disclose this. Group sessions will be led by a psychologist. The course materials (workbook, slides, and course instructions) will be shared on OSF.
Study: NCT06740110

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bone replacement composite vs standard of care
Description: Bone replacement composite: Before application the Bone replacement composite (size 10 mm) will be mixed with autogenous blood or a saline solution and modelled. Next, the medical device will be applied to the place where teeth extraction is performed.~Standard of care: Before application standard of care (Bio-Oss) will be mixed with autogenous blood or a saline solution and modelled. Next, the standard of care will be applied to the place where teeth extraction is performed. Subsequent application of a collagen membrane (Bio-Gide) will be conducted.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bone replacement composite vs standard of care
Description: Bone replacement composite: Before application the Bone replacement composite (size 10 mm) will be mixed with autogenous blood or a saline solution and modelled. Next, the medical device will be applied to the place where teeth extraction is performed.~Standard of care: Before application standard of care (Bio-Oss) will be mixed with autogenous blood or a saline solution and modelled. Next, the standard of care will be applied to the place where teeth extraction is performed. Subsequent application of a collagen membrane (Bio-Gide) will be conducted.
Study: NCT06740734

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stress ball
Description: Sterile Stress ball for pregnant women during mediolateral episiotomy repair. Participants in the stress ball group will be asked to squeeze and loosen the stress ball in their hands.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Expressive touch applications
Description: During the mediolateral episiotomy repair, expressive touch will be applied to one hand of the mother by the researcher, lasting approximately 15-20 minutes
Study: NCT06739889

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Elongation longitudinaux articular vertebral and columnar decoaption osteo-articulaire also known as ELDOA
Description: ELDOA targtes cervical and upper thoracic spine. ELDOA exercises involves spicific postural holds that improve forward neck posture.The goal of ELDOA is to help reduce stress and increase space in the vertebral joints so that muscles can move freely. The benefits of these stretches include joint mobility, increased fluid absorption in the discs of the spine, flexibility, improved muscle tone, postural alignment, body-mind connection, and coordination. The tension and release created by these stretches helps normalize the posture.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: upper thoracic mobilization
Description: Upper thoracic mobilization, often known as joint mobilization, is a common technique in manual therapy. In order to preserve or restore joint mobility, this approach glides and uses distraction on the joint surfaces.
Study: NCT06740695

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education group
Description: The training materials were prepared in line with the researchers and expert opinions were obtained. Trainings will be given for two weeks. After the trainings are completed, reminder information will be sent to the pregnant women via text messages every other day to inform them that the trainings are continuing. Reminder information prepared as text messages will be sent to the pregnant women's mobile phones. 4 weeks after the first training, the same training will be reminded again via WhatsApp as a summary training by emphasizing key points.~The trainings will be carried out by an expert researcher in the field. In the training content prepared in line with WhatsApp, the risks that may be seen during pregnancy and Gestational Diabetes Mellitus;~* Sensitivity perception and Seriousness perception, perceived risks that may be seen during pregnancy~* Health motivation perception, the pregnant woman's beliefs and practices regarding being healthy,~* Benefit perception, pregnancy follow
Study: NCT06284837

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Access site
Description: The SAFER-TAVI trial is randomized study comparing secondary access via a transradial versus transfemoral approach among patients undergoing transfemoral TAVI for aortic valve disease. Secondary access is gained along with primary access at the commencement of the TAVI procedure and is used for aortography before and after valve deployment and for assessment of the primary femoral access site after closure to confirm haemostasis. For patients assigned to radial access, the radial sheath will be removed using a radial band at the end of the procedure. For patients assigned to femoral access, the puncture site will be obtained under ultrasound guidance and fluoroscopic landmark identification. Unless contraindicated, the use of vascular closure devices will be recommended for all femoral cases. The choice of closure device is at the discretion of the operator. Catheters used in the access groups will be 5 or 6 French size at the discretion of the operator.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Access site
Description: The SAFER-TAVI trial is randomized study comparing secondary access via a transradial versus transfemoral approach among patients undergoing transfemoral TAVI for aortic valve disease. Secondary access is gained along with primary access at the commencement of the TAVI procedure and is used for aortography before and after valve deployment and for assessment of the primary femoral access site after closure to confirm haemostasis. For patients assigned to radial access, the radial sheath will be removed using a radial band at the end of the procedure. For patients assigned to femoral access, the puncture site will be obtained under ultrasound guidance and fluoroscopic landmark identification. Unless contraindicated, the use of vascular closure devices will be recommended for all femoral cases. The choice of closure device is at the discretion of the operator. Catheters used in the access groups will be 5 or 6 French size at the discretion of the operator.
Study: NCT06738979

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQF3510 (Semaglutide Injection)
Description: Semaglutide injection is a long-acting Glucagon-like peptide-1 (GLP-1) receptor agonist.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Wegovy®
Description: Active Comparator
Study: NCT06739187

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality platform on head mounted display
Description: Enhance Virtual Reality platform on a Meta Quest head mounted display
Study: NCT06739226

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Antigen-specific CAR T, CTL and DCvac to treat melanoma.
Description: Antigen-specific CAR T, CTL and DCvac to treat melanoma.
Study: NCT06739863

Intervention type: OTHER
Intervention: healthcare waste management
Description: To evaluate and compare the healthcare waste management practices in primary and secondary hospital Mianwali.~Focuses on assessing the current methods of waste disposal, segregation, treatment, and overall management in healthcare settings at two different levels of care: primary and secondary hospitals.
Study: NCT06739941

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oat fiber (BG-OS)
Description: Beta-glucan oligosaccharide (BG-OS) is beta-glucan predominant, dietary fiber obtained by extracting oat fiber from oat grain and applying a food-grade depolymerization process to shorten the polysaccharide chain length of the fiber. BG-OS retains the fiber structure of oat fiber but has a shorter chain length, which makes it water soluble and easily formulated into any food.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oat fiber (BG-OS)
Description: Beta-glucan oligosaccharide (BG-OS) is beta-glucan predominant, dietary fiber obtained by extracting oat fiber from oat grain and applying a food-grade depolymerization process to shorten the polysaccharide chain length of the fiber. BG-OS retains the fiber structure of oat fiber but has a shorter chain length, which makes it water soluble and easily formulated into any food.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oat fiber (BG-OS)
Description: Beta-glucan oligosaccharide (BG-OS) is beta-glucan predominant, dietary fiber obtained by extracting oat fiber from oat grain and applying a food-grade depolymerization process to shorten the polysaccharide chain length of the fiber. BG-OS retains the fiber structure of oat fiber but has a shorter chain length, which makes it water soluble and easily formulated into any food.
Study: NCT06739213

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYHA1813
Description: The starting dose of SYHA1813 is 20mg QD

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Investigator's Choice Treatment
Description: Investigator's Choice Treatment
Study: NCT06737900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional physical therapy
Description: * Heating pad for 10 minutes~* Core stability exercises for 20 minutes with 10 seconds of rest intervals~* Patients were advised to stretch for 5 minutes then perform lumber stability exercises.~* These stability exercises included side bridges, supine extension bridge, straight leg raise in prone lying, alternate arm and leg raise from quadruped position and prone bridges.~Both groups took sessions thrice a week for a total of 4 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: jandas approach
Description: * Stretching exercise for erector spinae and back extensors muscles~* Stretching exercises for iliopsoas muscle and rectus femoris muscle~* Strengthening exercise for abdominal muscle and gluteal maximus muscle Stretching exercise was performed actively for 3 repetitions x 1 set and 4 days a week Strengthening exercise was performed for 10 second hold and 10 repetitions. All Exercises was performed 3 times per week for total of 4 weeks
Study: NCT06739694

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PNE
Description: A manual therapy(Mulligan´s Mobilization with Movement) and 4 sessions of strenght exercises program was administered for both groups. In addition, a pain neuroscience education protocol was administered for the experimental group for a whole period of 4 weeks (1 session/week, 75mins per session).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Manual therapy
Description: 5 sessions of Mulligan´s Mobilization with Movement and 4 sessions of strenght exercises

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: 5 sessions of Mulligan´s Mobilization with Movement and 4 sessions of strenght exercises
Study: NCT06737523

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CVA
Description: Chiglitazar Sodium in combination with Venetoclax and Azacitidine
Study: NCT06740071

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: somatosensory interactive pelvic floor muscle training
Description: synchronized PFMT guidance through a combination of audio and video

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: somatosensory interactive pelvic floor muscle training
Description: synchronized PFMT guidance through a combination of audio and video
Study: NCT05202470

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TE
Description: After the first meeting, diabetes education videos prepared in two parts a week will be sent to the mobile phones of the individuals. The video submission will be completed in a total of four weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CE
Description: After the first meeting, diabetes education videos prepared in two parts a week will be sent to the mobile phones of the individuals. The video submission will be completed in a total of four weeks.
Study: NCT05165745

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Individualized Feedback
Description: Participants taking PrEP will receive questionnaires regarding self-reported weekly PrEP adherence; they will then receive individualized text-message or email feedback based on their self-reported adherence.
Study: NCT06168227

Intervention type: DRUG
Intervention: Disitamb Vedotin
Description: RC48-ADC based therapy
Study: NCT06276660

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: BCTT
Description: Participants will complete the Buffalo Concussion Treadmill Test, which involves individuals walking at 5.8 km/hr. (3.6 mph) at a 0.0% incline (5.1 km/hr. \[3.2 mph\] if below 5' 10 tall), the treadmill incline is increased 1 degree each minute for the first 15 minutes, then speed increased 0.64 km/hr. (0.4 mph) each minute thereafter.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamic ExIT
Description: The modified EXiT test will complete a 12 minute treadmill interval program followed by a dynamic circuit (10 squat jumps, 10 side to side push ups and 10 medicine ball rotations), jump ball toss, zig zag agility and arrow agility. Parameters will be recorded the same as the established dynamic EXiT test; heart rate and RPE will be recorded at 0, 2, 6:30 and 12 minutes of the treadmill program as well as after the second trial of each activity. The time to complete two trials of the zig zag agility and arrow agility will also be recorded.
Study: NCT05664243

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous genetically modified gamma-delta T cells
Description: Arm A: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with TMZ maintenance

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic genetically modified gamma-delta T cells
Description: Phase 1b and Arm B: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with D1 of TMZ 150mg/m2~Arms C: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with TMZ maintenance

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic genetically modified gamma-delta T cells
Description: Phase 1b and Arm B: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with D1 of TMZ 150mg/m2~Arms C: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with TMZ maintenance

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic genetically modified gamma-delta T cells
Description: Phase 1b and Arm B: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with D1 of TMZ 150mg/m2~Arms C: Cells will be administered on Day 1 of each of 6, 28-day cycles in combination with TMZ maintenance
Study: NCT05442086

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music and Theta Auditory Beat Stimulation
Description: Participants will listen to calm music with theta auditory beat stimulation for 24 minutes

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Pink Noise (control)
Description: Participants will listen to pink noise for 24 minutes
Study: NCT05695209

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coaching and Decision Aid
Description: Four (4) coaching sessions over approximately 12 weeks with integration of Decision Aid contents
Study: NCT04540094

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human albumin
Description: Any preparation of 5% Human Albumin Solution which has marketing authorisation in the UK to be used for this indication and is stocked by local hospital pharmacies at the participating sites, may be prescribed in this study

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Balanced crystalloid solution
Description: Any preparation of intravenous balanced crystalloid which has marketing authorisation in the UK to be used for this indication and is stocked by local hospital pharmacies at the participating sites, may be prescribed in this study.
Study: NCT05806684

Intervention type: OTHER
Intervention: ROP
Description: Correlation between neonatal indirect bilirubin jaundice and ROP.

Intervention type: OTHER
Intervention: ROP
Description: Correlation between neonatal indirect bilirubin jaundice and ROP.
Study: NCT06536231

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Remote ischemic conditioning
Description: Remote ischemic conditioning (RIC) procedure comprise three repetitions of brachial cuff inflation to 200 mmHg for five minutes following deflation to 0 mmHg for another five minutes. The procedure overall took 30 minutes.
Study: NCT06008912

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calisthenic Exercises
Description: Exercises for upper extremity, lower extremity and trunk which applying just patient's own body weight via using body mechanics. There is no need for any tools for exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercises
Description: Exercises which loading cardiovascular, respiratory and muscular system at the same time. Treadmill training will apply in the study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercises
Description: Exercises which loading cardiovascular, respiratory and muscular system at the same time. Treadmill training will apply in the study.