TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04691752

Intervention type: OTHER
Intervention: Audit
Description: Audit from clinical records
Study: NCT06564324

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Taletrectinib
Description: Approximately 138 ROS-1TKI- naïve ROS1+NSCLC patients will be randomized in a 1:1 ration to one of 2 study arms: Arm A: Taletrectinib monotherapy at 600 mg once daily (QD), continuously; Arm B: Crizotinib monotherapy at 250 mg twice daily (BID), continuously.~Each cycle duration will be 28 days. Participants will be treated until they experience progressive disease (PD) assessed by the blinded Independent Review Committee (BIRC), intolerable toxicity, or another discontinuation criterion is met.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Crizotinib
Description: Approximately 138 ROS-1TKI- naïve ROS1+NSCLC patients will be randomized in a 1:1 ration to one of 2 study arms: Arm A: Taletrectinib monotherapy at 600 mg once daily (QD), continuously; Arm B: Crizotinib monotherapy at 250 mg twice daily (BID), continuously.~Each cycle duration will be 28 days. Participants will be treated until they experience progressive disease (PD) assessed by the blinded Independent Review Committee (BIRC), intolerable toxicity, or another discontinuation criterion is met. Crossover from control group (crizotinib) to taletrectinib is also permitted, at the Investigator's discretion with the Sponsor's approval, for qualifying participants who have experienced objective progression confirmed by the BIRC.
Study: NCT05613400

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Simvastatin 10mg
Description: One simvastatin 10mg-tablet

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ezetimibe 10mg
Description: One ezetimibe 10mg-tablet
Study: NCT04859673

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: radial extracorpeal shock wave
Description: Swiss DolorClast® Master - Shockwave Therapy System will be used to apply the radial extracorporeal shock wave. It consists of master console, Evo Blue hand-piece, 15mm and 36mm interchangeable contact heads (applicators), contact gel, cart, and external compressor

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: radial extracorpeal shock wave
Description: Swiss DolorClast® Master - Shockwave Therapy System will be used to apply the radial extracorporeal shock wave. It consists of master console, Evo Blue hand-piece, 15mm and 36mm interchangeable contact heads (applicators), contact gel, cart, and external compressor
Study: NCT05545007

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Hypofractionated Radiosurgery (HSRS)
Description: HSRS converges multiple radiation beams to deliver a single, large dose of radiation to a discrete tumor target with high precision, thereby minimizing radiation dose to the surrounding normal tissue.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiosurgery (HSRS)
Description: HSRS converges multiple radiation beams to deliver a single, large dose of radiation to a discrete tumor target with high precision, thereby minimizing radiation dose to the surrounding normal tissue.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Brain metastases surgical resection
Description: Complete surgical resection of brain lesions with adeguate margins.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Brain metastases surgical resection
Description: Complete surgical resection of brain lesions with adeguate margins.
Study: NCT05856188

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Glutamine
Description: Biologic
Study: NCT05159128

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo to JNJ-75105186 will be administered orally in Parts 1 and 2.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo to JNJ-75105186 will be administered orally in Parts 1 and 2.
Study: NCT06411405

Intervention type: OTHER
Intervention: Maternal medical history
Description: See above; multiple factors to be collected broadly grouped into maternal medical, obstetric, and sociodemographic/lifestyle factors.
Study: NCT05856188

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Glutamine
Description: Biologic
Study: NCT05882357

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ELX/TEZ/IVA
Description: Fixed-dose combination granules for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ELX/TEZ/IVA
Description: Fixed-dose combination granules for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IVA
Description: Granules for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IVA
Description: Granules for oral administration
Study: NCT06556771

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gongs mobilization + conventional physical therapy
Description: 3 per week , mobilization for 5 minutes , exercise 3 sets for 10 repetitions for 4 consecutive weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kaltenborn mobilization along with traction + conventional therapy
Description: 3 per week , mobilization for 5 minutes , exercise 3 sets for 10 repetitions for 4 consecutive weeks.
Study: NCT06558331

Intervention type: OTHER
Intervention: Preoperative Quality of Recovery-15 (QoR-15T)
Description: The quality of recovery score (QoR)-15 questionnaire, preoperative

Intervention type: OTHER
Intervention: Preoperative Quality of Recovery-15 (QoR-15T)
Description: The quality of recovery score (QoR)-15 questionnaire, preoperative
Study: NCT06448637

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Drug Coated Balloon (DCB)
Description: Drug Coated Balloon (DCB) in patients with indication of Percutaneous Coronary Intervention (PCI)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Drug Eluting Stent (DES)
Description: Drug Eluting Stent (DES) in patients with indication of Percutaneous Coronary Intervention (PCI)
Study: NCT04904484

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iZephyr hood
Description: Assessment of an aerosol containment device
Study: NCT06558331

Intervention type: OTHER
Intervention: Postoperative 24th hour Quality of Recovery-15 (QoR-15T)
Description: The quality of recovery score (QoR)-15 questionnaire, postoperative 24th hour

Intervention type: OTHER
Intervention: Postoperative 24th hour Quality of Recovery-15 (QoR-15T)
Description: The quality of recovery score (QoR)-15 questionnaire, postoperative 24th hour
Study: NCT06416475

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Mankai supplementation
Description: The overall dose of the three Mankai duckweed beverages/day contains \~10 grams of dry matter.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Water consumption
Description: Water consumption
Study: NCT06039514

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GGTCA-AD mobile app
Description: The intervention will be done through an adaptation of the GGTCA app for teenagers: GGTCA-AD. This app is used to work on the dysfunctional beliefs that are associated with eating disorders. The app is made up of a series of levels comprising the topics that are normally worked on in cognitive behavior therapy (CBT) in relation to eating disorders. At each level, affirmations in the form of beliefs appear on the screen, and the person must accept them if they are functional, adaptive and positive; or reject them if they are dysfunctional, maladaptive and negative.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: GGNeutra mobile app
Description: the control group will complete another module belonging to the GGTUDE digital platform. Specifically, this app is called GGNEUTRA, and the statements that compose it are totally independent of the target of the study. The operation is similar, sentences appear in the center of the screen, but in this case, the person must accept those sentences that are true, for example: Madrid is the capital of Spain, by dragging it to the top of the screen; and reject those that are false, for example: Tokyo is the capital of Spain, by dragging it to the bottom of the screen.
Study: NCT04788693

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical rehabilitation of gait with motor imagery
Description: Physical rehabilitation of gait is a type of non-invasive treatment that seeks to change the way of performing a task or motor function (in this case, gait) through movement modification and corrected repeated practice, taking into account the alterations, limitations and considerations related to the disease suffered by the person. In this intervention, in addition to physical exercise to correct gait, mental exercises will be included in which the patient visualizes himself performing the exercises that he will then develop with the body.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical rehabilitation of gait without motor imagery
Description: Physical rehabilitation of gait is a type of non-invasive treatment that seeks to change the way of performing a task or motor function (in this case, gait) through movement modification and corrected repeated practice, taking into account the alterations, limitations and considerations related to the disease suffered by the person. Motor imagery exercises are not included in this program.
Study: NCT06641336

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RehAtt
Description: Each patient received the RehAtt intervention.
Study: NCT06589999

Intervention type: DIAGNOSTIC_TEST
Intervention: MP2RAGE sequence
Description: Addition of MRI sequence MP2RAGE
Study: NCT06669702

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 12-week home based exercise
Description: Patients allocated to the exercise arm will be prescribed a home-based walking exercise programme consisting of 30 minutes of walking on 5 days per week at an rating of perceived exertion in the range of 12-14 (somewhat hard). Each patient's heart rate range will be established during the baseline exercise test by recording the heart rate response at the required RPE target range. This will be provided to each patient to use in conjunction with the activity monitor they will be given to wear on their non-dominant wrist. The monitor reports heart rate and records daily steps, distance and activity duration.~Participants can break down the exercise time in a way that suits their time, i.e., they can do 3 × 10 minutes, 2 × 15 minutes, etc.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine care
Description: Participants in this group will continue with their current routine care and will be given a diary of exercises that they can do, which are usually given to them as part of their health care routine by physiotherapists or consultants. The diary has information about yoga-like stretching practices.
Study: NCT06459804

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electro Dry Needling
Description: Standard Physiotherapy:~It will include Hot pack (10 min), Stretching of levator scapulae (3 times with 30 seconds hold), Scapular stabilization exercises (10 times with 5 seconds hold).~Scapular Stabilization exercises will be comprised of four exercise programs. The participants will sit on the knees in 90° flexion position, and a Swiss ball will be propped up between the stomach and chest.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dry Needling
Description: Dry Needling
Study: NCT06392932

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: QDOT Micro ablation catheter
Description: QDOT Micro ablation catheter

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ST SF ablation catheter
Description: ST SF ablation catheter
Study: NCT06554171

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hippotherapy group
Description: In addition to conventional physiotherapy, training will be given in the Hippotherapy Simulator for 15 minutes a day, 5 days a week for 4 weeks. The hippotherapy simulator serves a wide range of purposes from recreational use that mimics the movements of a real horse or can make similar movements, to fitness, exercise, sports, education and therapy and is suitable for use by individuals with cerebral palsy.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control group
Description: In addition to conventional physiotherapy, the control group will be allowed to sit in the Hippotherapy Simulature for 15 minutes a day, 5 days a week for 4 weeks. However, the simulator will be kept in closed position to prevent oscillations.
Study: NCT04881565

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Reactive balance training
Description: During each one-hour session, participants will experience 40-50 perturbations (i.e. approximately one perturbation per training minute) during standing and/or walking activities. The perturbations will be applied in any direction (e.g. forwards, sideways, backwards, etc.) To create a perturbation, the researcher will apply unexpected pushes or pulls to a safety harness at waist level. The perturbation will be sufficient in magnitude to elicit a stepping response from the participant. Throughout the session, participants will complete challenging balance tasks, customized to their ability level. Balance tasks will be organized into five categories: stable, quasi-mobile, mobile, unpredictable and participant-selected.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reactive balance training
Description: During each one-hour session, participants will experience 40-50 perturbations (i.e. approximately one perturbation per training minute) during standing and/or walking activities. The perturbations will be applied in any direction (e.g. forwards, sideways, backwards, etc.) To create a perturbation, the researcher will apply unexpected pushes or pulls to a safety harness at waist level. The perturbation will be sufficient in magnitude to elicit a stepping response from the participant. Throughout the session, participants will complete challenging balance tasks, customized to their ability level. Balance tasks will be organized into five categories: stable, quasi-mobile, mobile, unpredictable and participant-selected.
Study: NCT05650996

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ADL/Cast Care instruction
Description: Participants in the experimental group will watch a video instructing them on early ADL participation after DRF fracture treated in a cast and cast care. Participants in the experimental group will also receive a handout on ADL participation and cast care.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cast Care Instruction
Description: Participants in the control group will watch a video instructing them on cast care. Participants in the control group will receive a handout on cast care.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cast Care Instruction
Description: Participants in the control group will watch a video instructing them on cast care. Participants in the control group will receive a handout on cast care.
Study: NCT04282915

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reducing Stigma among Healthcare Providers (RESHAPE)
Description: Mental health service users are trained using Photo Voice to develop recovery story testimonials. They then participate in primary care providers mental health Gap Action Programme training. In addition, aspirational figures are trained to provider testimonials and conduct myth-busting.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: mental health Gap Action Programme
Description: The mental health Gap Action Programme is a training program for primary care providers in mental health services. The curriculum has been developed by the World Health Organization and was adapted in Nepal and certified by the Ministry of Health.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mental health Gap Action Programme
Description: The mental health Gap Action Programme is a training program for primary care providers in mental health services. The curriculum has been developed by the World Health Organization and was adapted in Nepal and certified by the Ministry of Health.
Study: NCT06673654

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib Topical Cream 1.5%
Description: The investigational product is to be self-administered by applying a thin layer twice daily to cover the affected areas up to 20% body surface area for approximately 8 weeks. The maximum weekly dose of the study drug should not exceed 60 g.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: OPZELURA (Ruxolitinib) Cream
Description: The investigational product is to be self-administered by applying a thin layer twice daily to cover the affected areas up to 20% body surface area for approximately 8 weeks. The maximum weekly dose of the study drug should not exceed 60 g.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The investigational product is to be self-administered by applying a thin layer twice daily to cover the affected areas up to 20% body surface area for approximately 8 weeks. The maximum weekly dose of the study drug should not exceed 60 g.
Study: NCT06240130

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Partial pulpotomy
Description: after caries removal and pulp exposure pulp tissue is amputated and wound lavage done with 3% NaOCl in partial pulpotomy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Partial pulpotomy
Description: after caries removal and pulp exposure pulp tissue is amputated and wound lavage done with 2% Chlorhexidine in partial pulpotomy
Study: NCT05369767

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAD, SHR-2004
Description: Ascending dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SAD, SHR-2004 placebo
Description: Ascending dose
Study: NCT06412224

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RRG001
Description: Administered by subretinal injection. Dosage form: injection.
Study: NCT05890950

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: K-757 and K-833
Description: Both administered orally

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching placebo to K-757 and K-833
Description: Both administered orally
Study: NCT03866954

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: EE-TP
Description: Ecoli thymidine phoshorylase encapsulated within autologous erythrocytes
Study: NCT05025124

Intervention type: DEVICE
Intervention: Entia Liberty
Description: Home monitoring system

Intervention type: DEVICE
Intervention: Entia Liberty
Description: Home monitoring system
Study: NCT05479539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Action observation therapy
Description: Participants will watch 12-minute video-clips followed by 8 minutes of motor imagery. Video-clips observation and imagination will be focused un shoulder tasks occuring on the three planes of motion.
Study: NCT05399238

Intervention type: DEVICE
Intervention: The objective is to measure the temperature of the lingual dorsum
Description: Subjects will make one visit to our clinic with burning mouth syndrome and control healthy . They will be asked to acclimate to room temperature for at least 20 minutes. Subjects are requested not to consume hot drinks or food for at least an hour before imaging and not to use any skin preparations.

Intervention type: DEVICE
Intervention: The objective is to measure the temperature of the lingual dorsum
Description: Subjects will make one visit to our clinic with burning mouth syndrome and control healthy . They will be asked to acclimate to room temperature for at least 20 minutes. Subjects are requested not to consume hot drinks or food for at least an hour before imaging and not to use any skin preparations.
Study: NCT05633576

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: steroid eye drops
Description: Self-administration of steroid eye drops three times a day for four consecutive weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Self-administration of placebo eye drops three times a day for four consecutive weeks.
Study: NCT06503055

Intervention type: OTHER
Intervention: Questionnaire
Description: A questionnaire targeting a convenience sample of medical field professionals including physicians with different specialties, pharmacists, medical students, nursing staff, and the general population in Gharbia governorate (about 1000 subjects).~The questionnaire will be written and digital in both Arabic and English versions. Moreover, an awareness campaign will be designed to educate the participants on appropriate antibiotic use principles.

Intervention type: OTHER
Intervention: Questionnaire
Description: A questionnaire targeting a convenience sample of medical field professionals including physicians with different specialties, pharmacists, medical students, nursing staff, and the general population in Gharbia governorate (about 1000 subjects).~The questionnaire will be written and digital in both Arabic and English versions. Moreover, an awareness campaign will be designed to educate the participants on appropriate antibiotic use principles.
Study: NCT06151483

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Alpha-Agonist
Description: The maternal systolic blood pressure was consistently maintained above 80% of the preoperative baseline value from the initiation of spinal anesthesia until fetal delivery.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: α-adrenergic receptor agonist
Description: The maternal systolic blood pressure was consistently maintained above 90% of the preoperative baseline value from the initiation of spinal anesthesia until fetal delivery.
Study: NCT06625372

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: SMOF lipid
Description: The SMOF lipid is given to the patient as a fat component of total parenteral nutrition.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: INTRALIPIDS
Description: The Intralipid will be given to the patient as fat component of total parenteral nutrition.
Study: NCT05509127

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modified universal adhesive
Description: Application of the modified universal adhesive is done according to manufacturer's instructions using a micro-brush. It is actively rubbed for 20 seconds, gently air-dried for 5 seconds then light cured for 20 seconds.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Conventional universal adhesive
Description: Application of the conventional Single Bond Universal adhesive is done using a micro-brush followed by rubbing for 20 seconds, gentle air drying for 5 seconds then light curing for 20 seconds.
Study: NCT05366751

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAGE-324
Description: SAGE-324 oral tablets