TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05416853

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Carotid Artery Stenting (CAS)
Description: CAS involves insertion of a catheter or tube into an artery in the groin or the radial, and then threading the catheter through the arteries of the body to the location of the plaque within the carotid artery in the neck. A stent is then placed to cover the plaque and hold the artery open.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Carotid Artery Stenting (CAS)
Description: CAS involves insertion of a catheter or tube into an artery in the groin or the radial, and then threading the catheter through the arteries of the body to the location of the plaque within the carotid artery in the neck. A stent is then placed to cover the plaque and hold the artery open.
Study: NCT05613218

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen
Description: Patients will have nasal cannula or oxygen mask placed as the usual standard of care.~Patients will be screened and randomized in the emergency department to either liberal or restrictive oxygenation after providing informed written consent and oxygen is titrated to the prespecified target range using an automated feedback device (O2MATIC). Consented patients will be randomly allocated to study groups via the web-based system within REDCap. The allocation will be concealed. Time at randomization will be considered as study time zero (T0). All patients will receive usual standard of care except for their O2 management. The intervention will last for 24 h. After 24 h, patients will be switched over to usual care for oxygen therapy. If the treating physician thinks, that the patient need another oxygenation target and it is thought to be harmful to continue with the allocated target, the intervention-phase can be stopped prematurely.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen
Description: Patients will have nasal cannula or oxygen mask placed as the usual standard of care.~Patients will be screened and randomized in the emergency department to either liberal or restrictive oxygenation after providing informed written consent and oxygen is titrated to the prespecified target range using an automated feedback device (O2MATIC). Consented patients will be randomly allocated to study groups via the web-based system within REDCap. The allocation will be concealed. Time at randomization will be considered as study time zero (T0). All patients will receive usual standard of care except for their O2 management. The intervention will last for 24 h. After 24 h, patients will be switched over to usual care for oxygen therapy. If the treating physician thinks, that the patient need another oxygenation target and it is thought to be harmful to continue with the allocated target, the intervention-phase can be stopped prematurely.
Study: NCT06118788

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BG1805
Description: A single infusion of BG1805 Injection administered intravenously.
Study: NCT04643652

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noise Reduction Bundle
Description: Implementation of a bundle of noise reducing interventions. This concerns among other things:~reduction of alarms, phone calls/pagers/ beepers, introduction of a defined period in which there is a reduction of controllable sound (quiet time), etc
Study: NCT05957471

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: BC3195 for Injection
Description: BC3195 via intravenous(IV).
Study: NCT05310175

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: Filiform needles (0.30×50mm, Hanyi brand, Beijing Medical Appliance, China) and the SDZ-V electric acupuncture (Suzhou Medical Appliance) apparatus will be used. After acupuncture at the acupoints group, the needle handle will be connected with the electrode of the electric acupuncture apparatus.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham acupuncture
Description: Shallow needle insertion of 2-3 mm at sham acupoints without manipulation.
Study: NCT05523778

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: placement of pancreatic duct stents before enucleation surgery
Description: Advance placement of pancreatic stents endoscopically

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Direct enucleation surgery
Description: Patients will receive direct enucleation surgery
Study: NCT05549752

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Flecainide Injectable Solution
Description: Intravenous Flecainide at a dose of 2.0mg/kg (maximum dose: 150mg) in 100ml D/W 5% for 10 minutes.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amiodarone Injectable Solution
Description: Intravenous Amiodarone at a dose of 5.0-7.0 mg/kg for 1 hour, and maintenance dose of 50mg/h (maximum dose: 1000mg) for up to 24 hours.
Study: NCT05250388

Intervention type: PROCEDURE
Intervention: Arthroscopic Bankart repair
Description: Arthroscopic Bankart repair is a minimally invasive surgical procedure with the aim to reattach and tighten the detached labrum and ligaments within the shoulder joint.
Study: NCT04794712

Intervention type: DEVICE
Intervention: Venous reflux tools (Ultrasound and Photo plethysmography (PPG))
Description: Venous reflux tools Pain assessment tools

Intervention type: DEVICE
Intervention: Venous reflux tools (Ultrasound and Photo plethysmography (PPG))
Description: Venous reflux tools Pain assessment tools
Study: NCT04199130

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BrainHQ
Description: BrainHQ is a web-based brain-training program. The investigators will assign participants to attention specific modules that they will complete at home with the goal of restoring attentional functions lost through injury via repetitive tasks of graded difficulty.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BrainHQ
Description: BrainHQ is a web-based brain-training program. The investigators will assign participants to attention specific modules that they will complete at home with the goal of restoring attentional functions lost through injury via repetitive tasks of graded difficulty.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal Management Training
Description: This is a manualized, interactive, metacognitive-strategy training designed to promote a mindful approach to complex real-life tasks and reduce lapses in attention via implementation of compensatory mechanisms for monitoring tasks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal Management Training
Description: This is a manualized, interactive, metacognitive-strategy training designed to promote a mindful approach to complex real-life tasks and reduce lapses in attention via implementation of compensatory mechanisms for monitoring tasks.
Study: NCT05480111

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthesia at incision site
Description: 20 ml of 0.25% Bupivacaine will be given at incision site

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sham QL
Description: 20 mls of normal saline given at QL.The QL block will be administered on both the right and left sides. The transducer is placed transverse immediately cranial to the iliac crest and at the level of the posterior axillary line. The needle is then inserted inplane from the lateral edge of the transducer and advanced through the quadratus lumborum (QL) muscle until the needle tip penetrated the epimysium of the anterior part of the QL muscle. The anesthetic is injected after repeated negative aspiration tests for blood in the fascial interspace between the QL and psoas major (PM) muscles posterior to the transversalis fascia

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sham Local
Description: 20 mls of normal saline given at incision site

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QL
Description: QL block involves injection of 19 ml of 0.25% Bupivacaine and iml(4mg) of Decadron in a fascial place formed partly by the posterior surface of the quadratus lumborum muscle.The QL block will be administered on both the right and left sides. The transducer is placed transverse immediately cranial to the iliac crest and at the level of the posterior axillary line. The needle is then inserted inplane from the lateral edge of the transducer and advanced through the quadratus lumborum (QL) muscle until the needle tip penetrated the epimysium of the anterior part of the QL muscle. The anesthetic is injected after repeated negative aspiration tests for blood in the fascial interspace between the QL and psoas major (PM) muscles posterior to the transversalis fascia
Study: NCT05478525

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLY-200
Description: 0.5 g GLY-200 (1 x 0.5 g capsule) BID for 14 days (n=12)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLY-200
Description: 1.0 g GLY-200 (2 x 0.5 g capsules) BID for 14 days (n=12)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLY-200
Description: 2.0 g GLY-200 (4 x 0.5 g capsules) BID for 14 days (n=12)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 placebo capsule BID for 14 days (n=4)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 placebo capsules BID for 14 days (n=4)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 4 placebo capsules BID for 14 days (n=4)
Study: NCT04930341

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-Acupressure
Description: Acupressure is a therapy method performed with an instrument or hand, fingertip, palm, elbow, knee, thumb relaxation and wrist bands on various points representing the waist organs in order to ensure the continuation and balance of the energy in our body.
Study: NCT04986436

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10360
Description: Single or multiple dose(s) of HS-10360

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single or multiple dose(s) of Placebo
Study: NCT05433285

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 Protein Subunit Recombinant Vaccine
Description: SARS-CoV-2 RBD subunit recombinant protein, manufactured by PT. Bio Farma

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator
Description: Covovax® COVID-19 vaccine is a protein-based vaccine candidate engineered from the genetic sequence of the first strain of the SARS-CoV-2 betacoronavirus
Study: NCT05008900

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Salvage radiotherapy
Description: Standard of care salvage radiotherapy to the prostate bed which may include the lymph nodes.
Study: NCT05143372

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vibrolung
Description: Vibroacoustic respiratory therapy
Study: NCT04794712

Intervention type: DEVICE
Intervention: Venous reflux tools (Ultrasound and Photo plethysmography (PPG))
Description: Venous reflux tools Pain assessment tools
Study: NCT05466370

Intervention type: BIOLOGICAL
Intervention: Transfusion of Allogeneic Blood
Description: Transfusion of Allogeneic Blood

Intervention type: BIOLOGICAL
Intervention: Transfusion of Allogeneic Blood
Description: Transfusion of Allogeneic Blood

Intervention type: BIOLOGICAL
Intervention: Transfusion of Allogeneic Blood
Description: Transfusion of Allogeneic Blood

Intervention type: BIOLOGICAL
Intervention: Transfusion of Allogeneic Blood
Description: Transfusion of Allogeneic Blood
Study: NCT04966663

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Antineoplastic agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Antineoplastic agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Antineoplastic agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Antineoplastic agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Antineoplastic agent

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ctDNA blood test
Description: Blood will be collected for ctDNA testing

Intervention type: PROCEDURE
Group type: OTHER
Intervention: ctDNA blood test
Description: Blood will be collected for ctDNA testing
Study: NCT05710445

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augmented Reality
Description: Mixed reality smart glasses will be used to view a virtual monitor which mirrors the ultrasound screen in real-time.
Study: NCT05555420

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SRP+Laser
Description: Non-surgical periodontal therapy in combination with Laser

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SRP+Laser
Description: Non-surgical periodontal therapy in combination with Laser
Study: NCT06109961

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxygen Gas for Inhalation
Description: The active Hyperbaric Oxygen Therapy (HBOT) arm will receive 100% oxygen at 2.0-2.5 atmospheres (ATM).

Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care
Description: The accepted standard of care for perianal Crohn's disease (PCD) involves conventional therapies such as immunosuppressive agents and biologics, which can be used to induce and maintain fistula remission.
Study: NCT06069895

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0113-6856
Description: NNC0113-6856 will be administered as oral tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: NNC0113-6856 matching placebo will be administered as oral tablets.
Study: NCT05842161

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: QUIT-AD
Description: An adapted, six-session cognitive behavioral therapy intervention for smoking cessation and treatment adherence

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Treatment as Usual
Description: Standard treatment for HIV/TB with one session of psychoeducation.
Study: NCT01796405

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clofarabine
Study: NCT05820906

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab+Regorafenib+GC
Description: Cadonilimab:10mg/kg, iv,q3w,D1 Regorafenib: 80mg, po, orally once daily Gemcitabine:1000 mg/m2, iv, Q3W，D1,D8 Cisplatin:25 mg/m2, iv, Q3W, D1,D8
Study: NCT05355883

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remote Ischemic Conditioning (RIC)
Description: See descriptions under arm/group descriptions. RIC is delivered for 5 intervention visits. Visits 1 is the pre-training assessment visit, visits 2-6 are RIC plus training visits, visit 7 is a post-training assessment visit.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham conditioning
Description: See descriptions under arm/group descriptions. Sham conditioning is delivered for 5 intervention visits. Visits 1 is the pre-training assessment visit, visits 2-6 are RIC plus training visits, visit 7 is a post-training assessment visit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hand Arm Bimanual Intensive Therapy (HABIT)
Description: HABIT is a child-friendly, intensive intervention directed at improving bimanual coordination and function of the affected arm. The intervention employed in this study includes various age-appropriate fine and gross motor bimanual activities that will be delivered in a play context. Children practice bimanual activities for 6 hours per day, 5 days per week, for 1 week.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Hand Arm Bimanual Intensive Therapy (HABIT)
Description: HABIT is a child-friendly, intensive intervention directed at improving bimanual coordination and function of the affected arm. The intervention employed in this study includes various age-appropriate fine and gross motor bimanual activities that will be delivered in a play context. Children practice bimanual activities for 6 hours per day, 5 days per week, for 1 week.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bimanual Cup Stacking Training
Description: Children practices bimanual cup stacking, 15 trials/day for 5 consecutive day.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Bimanual Cup Stacking Training
Description: Children practices bimanual cup stacking, 15 trials/day for 5 consecutive day.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Balance training
Description: All children undergo training on a balance board, learning to hold the board level with equal weight on each leg and using various bilateral upper extremity strategies. Participants perform the balance task for 15, 30-second trials per day at visits 2-6.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Balance training
Description: All children undergo training on a balance board, learning to hold the board level with equal weight on each leg and using various bilateral upper extremity strategies. Participants perform the balance task for 15, 30-second trials per day at visits 2-6.
Study: NCT04818593

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ZyMot Multi Sperm Separation Device (850 ul)
Description: 850 uL of untreated semen will be directly deposited into the inlet port of the ZyMotTM Multi device, followed by placement of 750 uL culture medium in the outlet port and throughout the upper collection chamber. The device will then be incubated in a humidified 37C CO2 incubator for 30 minutes. During incubation, the healthiest and most motile sperm will swim through the microporous filter and into the upper collection chamber, where they will be recovered via the outlet port. 500 uL of the sperm sample will be removed and placed in a separate tube for analysis and insemination.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Density Gradient Centrifugation
Description: Density gradient centrifugation will be performed using a one-layer preparation of 90% Isolate in 15 mL conical tubes. Semen will be layered over 1 mL of gradient and then centrifuged for 15 min at 300xg. The supernatant will be removed and discarded. The sperm pellet will be washed by mixing with Multipurpose Handling Medium Complete and centrifuging the sample for 5 min at 400xg. After the wash, the supernatant is removed and discarded and the pellet is re-suspended in culture medium, assessed for sperm parameters, and held at room temperature until insemination.
Study: NCT05297981

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: The patient will be placed in lateral decubitus position. A high frequency linear probe of a transportable Fuji M-Turbo ultrasound system will be placed on the spinous process at T8 level on the parasagittal plane and then slide 2.5-3 cm laterally to visualize the transverse process and erector spinae muscle. Using the inplane technique,then 0.5 ml/kg of 0.25% bupivacaine will be injected between the muscle and transverse process. The same procedure will be performed bilaterally.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Quadratus lumborum block
Description: The patient will be placed in the lateral decubitus position. A low frequency curved probe of a transportable Fuji M-Turbo ultrasound system will be placed horizontally in the anterior axillary line midway between the subcostal margin and the iliac crest to identify the triple abdominal muscle layers.A 22-G, 80-mm needle echogenic needle will be inserted in plane relative to the US probe, into the posterior aspect of the QL muscle (between QL and erector spinae muscle); this is known as QLB type 2. Then, 0.5 ml/kg of 0.25% bupivacaine will be injected behind the muscle as a bolus dose. The block will be performed bilaterally.
Study: NCT06170411

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Elexir (program1)
Description: The Elexir is an external cranial neurostimulator designed for supraorbital neurostimulation, also known as Trigeminal Nerve Stimulation. The Elexir will deliver trigeminal nerve stimulation.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham device
Description: The sham device will deliver sham trigeminal nerve stimulation.
Study: NCT06539923

Intervention type: OTHER
Intervention: retrieving data
Description: Data will be retrieved retrospectively
Study: NCT06446440

Intervention type: PROCEDURE
Intervention: Laparoscopic adhesiolysis
Description: Laparoscopic adhesiolysis

Intervention type: PROCEDURE
Intervention: Open adhesiolysis
Description: Open adhesiolysis
Study: NCT06300658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: Patient will receive preemptive stellate ganglion block (SGB) just before spinal anesthesia.
Study: NCT05182957

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD-1 monoclonal antibody
Description: Anti-PD-1 monoclonal antibody, 200mg i.v d1 (/21d)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide 25mg qd po d1-d10 (/21d)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Azacitidine 75mg/m2 i.v d1-d7 (/21d)
Study: NCT04956159

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
Description: rTMS is a non-invasive procedure in which cerebral electrical activity is influenced by a rapidly changing magnetic field. The magnetic field is created by a plastic-encased coil which is placed over the patient's scalp. The magnetic field can be directed onto specific areas of the brain. rTMS can modulate cerebral activity by low or high frequencies. Over time, the magnetic field pulses can gradually change the activity level of the stimulated brain region and help symptoms of depression and anxiety.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham rTMS
Description: Sham rTMS involves a click replicating the sound of the magnetic discharge, without any magnetic pulse being delivered.
Study: NCT06116825

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1450ppm Fluoride toothpaste
Description: 1450ppm Fluoride toothpaste

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 1000Pppm Fluoride toothpaste
Description: 1000Pppm Fluoride toothpaste
Study: NCT05073809

Intervention type: DIAGNOSTIC_TEST
Intervention: Photoacoustic Imaging Scan
Description: A relatively novel modality that combines exquisite spatial resolution with the ability to image multiple biological tissues, including blood, water and lipid.

Intervention type: DIAGNOSTIC_TEST
Intervention: Photoacoustic Imaging Scan
Description: A relatively novel modality that combines exquisite spatial resolution with the ability to image multiple biological tissues, including blood, water and lipid.
Study: NCT04806607

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 19G FNB
Description: Biopsy specimen adequacy using the 19G FNB

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 19G FNB
Description: Biopsy specimen adequacy using the 19G FNB

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 22G FNB
Description: Biopsy specimen adequacy using the 22G FNB.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 22G FNB
Description: Biopsy specimen adequacy using the 22G FNB.
Study: NCT06263569

Intervention type: PROCEDURE
Intervention: Total hip arthroplasty
Description: Unilateral primary total hip arthroplasty procedure.