Study: NCT06418633

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 60-minute walking test
Description: Treadmill walking test in the morning, 2 hours after breakfast, following a clinical examination, resting 12-lead electrocardiogram and blood pressure measurement. After a 3-minute warm-up and walking of speed 2.5 km per hour, no incline, the speed and incline are gradually increased to reach a target heart rate close to the theoretical ventilatory threshold, around 70% of the theoretical maximum value (evaluated by Astrand's formula: 220-age), i.e. aerobic conditions of moderate intensity so that prolonged effort can be maintained. Test performed in presence of a physician trained in stress testing. Emergency cart and defibrillator available in the department. Intra-hospital vital emergency protocol in place, with resuscitation teams on standby. The cardiology department, in the same building, can be contacted in the event of a cardiological abnormality during the test or recovery. The test takes 60 minutes, including a 3-minute initial warm-up.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 60-minute walking test
Description: Treadmill walking test in the morning, 2 hours after breakfast, following a clinical examination, resting 12-lead electrocardiogram and blood pressure measurement. After a 3-minute warm-up and walking of speed 2.5 km per hour, no incline, the speed and incline are gradually increased to reach a target heart rate close to the theoretical ventilatory threshold, around 70% of the theoretical maximum value (evaluated by Astrand's formula: 220-age), i.e. aerobic conditions of moderate intensity so that prolonged effort can be maintained. Test performed in presence of a physician trained in stress testing. Emergency cart and defibrillator available in the department. Intra-hospital vital emergency protocol in place, with resuscitation teams on standby. The cardiology department, in the same building, can be contacted in the event of a cardiological abnormality during the test or recovery. The test takes 60 minutes, including a 3-minute initial warm-up.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 60-minute walking test
Description: Treadmill walking test in the morning, 2 hours after breakfast, following a clinical examination, resting 12-lead electrocardiogram and blood pressure measurement. After a 3-minute warm-up and walking of speed 2.5 km per hour, no incline, the speed and incline are gradually increased to reach a target heart rate close to the theoretical ventilatory threshold, around 70% of the theoretical maximum value (evaluated by Astrand's formula: 220-age), i.e. aerobic conditions of moderate intensity so that prolonged effort can be maintained. Test performed in presence of a physician trained in stress testing. Emergency cart and defibrillator available in the department. Intra-hospital vital emergency protocol in place, with resuscitation teams on standby. The cardiology department, in the same building, can be contacted in the event of a cardiological abnormality during the test or recovery. The test takes 60 minutes, including a 3-minute initial warm-up.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 60-minute walking test
Description: Treadmill walking test in the morning, 2 hours after breakfast, following a clinical examination, resting 12-lead electrocardiogram and blood pressure measurement. After a 3-minute warm-up and walking of speed 2.5 km per hour, no incline, the speed and incline are gradually increased to reach a target heart rate close to the theoretical ventilatory threshold, around 70% of the theoretical maximum value (evaluated by Astrand's formula: 220-age), i.e. aerobic conditions of moderate intensity so that prolonged effort can be maintained. Test performed in presence of a physician trained in stress testing. Emergency cart and defibrillator available in the department. Intra-hospital vital emergency protocol in place, with resuscitation teams on standby. The cardiology department, in the same building, can be contacted in the event of a cardiological abnormality during the test or recovery. The test takes 60 minutes, including a 3-minute initial warm-up.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Static blood test
Description: 33.3 ml of blood will be taken from each participant whilst at rest, before undergoing the 60-minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Static blood test
Description: 33.3 ml of blood will be taken from each participant whilst at rest, before undergoing the 60-minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Static blood test
Description: 33.3 ml of blood will be taken from each participant whilst at rest, before undergoing the 60-minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Static blood test
Description: 33.3 ml of blood will be taken from each participant whilst at rest, before undergoing the 60-minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Post-effort blood test
Description: 33.3 ml of blood will be taken from each participant immediately after undergoing the 60-minute walking test.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Post-effort blood test
Description: 33.3 ml of blood will be taken from each participant immediately after undergoing the 60-minute walking test.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Post-effort blood test
Description: 33.3 ml of blood will be taken from each participant immediately after undergoing the 60-minute walking test.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Post-effort blood test
Description: 33.3 ml of blood will be taken from each participant immediately after undergoing the 60-minute walking test.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrocardiogram
Description: An electrocardiogram will be carried out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrocardiogram
Description: An electrocardiogram will be carried out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrocardiogram
Description: An electrocardiogram will be carried out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrocardiogram
Description: An electrocardiogram will be carried out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood pressure monitoring
Description: Blood pressure will be monitored out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood pressure monitoring
Description: Blood pressure will be monitored out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood pressure monitoring
Description: Blood pressure will be monitored out throughout the exercise period and during the first 30 minutes of recovery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood pressure monitoring
Description: Blood pressure will be monitored out throughout the exercise period and during the first 30 minutes of recovery.