TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05938816

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction (MBSR)
Description: MBSR consists of weekly two-hour sessions for eight weeks, and a 7.5 hour retreat between weeks 6 and 7. The MBSR intervention will be facilitated by an experienced and certified MBSR teacher. MBSR curriculum strongly encourages completion of home practice assignments (\~30 minutes daily) to help integration of concepts into daily life. Participants will receive audio CDs and a DVD to help guide home practice.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Health and Wellness Education (HWE)
Description: HWE is a didactic-based group intervention designed as an active comparator for randomized-controlled trials of MBSR. HWE provides instruction to participants regarding improving their emotional and physical health. In contrast to MBSR, there are no attempts to train participants' breathing, movement, or meditation habits or practices. HWE is administered in 8 weekly 2.5-hour classes with home practice to be completed between sessions (matched to MBSR for amount and effort). HWE also features one extended 7.5-hour retreat, similar to MBSR.84 Dr. Autumn Gallegos (consultant) has conducted trials of MBSR among veterans with PTSD using a HWE control group, and will provide mentorship to the PI in administering the HWE intervention. Dr. Kaplan and a trained RA will facilitate HWE.
Study: NCT05512364

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elacestrant
Description: 400mg QD orally on a continuous dosing schedule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tamoxifen
Description: 20 mg QD orally on a continuous dosing schedule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Letrozole 2.5mg
Description: 2.5 mg QD orally on a continuous dosing schedule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anastrozole 1mg
Description: 1 mg QD orally on a continuous dosing schedule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exemestane 25 MG
Description: 25 mg QD orally on a continuous dosing schedule
Study: NCT05032430

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CCC
Description: A mix of mindfulness-based stress reduction, mindful eating, and mindful parenting strategies.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: Consists of strategies meant to enhance health and well-being (e.g., health education, strategies to get more physical activity) but does not include mindfulness as an active ingredient.
Study: NCT04807569

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peripheral magnetic neuromodulation
Description: Non-invasive peripheral magnetic neuromodulation using the BTL Emsella magnetic stimulator according to the manufacturer's standard protocol: pelvic floor rehabilitation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Taking drug Tamsulosin
Description: Tamsulosin at a dose of 0.4 mg x 1 time per day orally for 1 month.
Study: NCT06139380

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine
Description: This is medication which is commonly used for sedation in the emergency department. At the analgesic dose, this medication can be used to reduce the pain via other routes such as intranasal.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sterile water
Description: Intranasal sterile water was administered via syringe.
Study: NCT05938881

Intervention type: PROCEDURE
Intervention: self-cut mesh procedure
Description: transvaginal mesh procedure using self-cut mesh

Intervention type: PROCEDURE
Intervention: mesh-kit procedure
Description: transvaginal mesh procedure using mesh-kit
Study: NCT05325138

Intervention type: OTHER
Intervention: Interview
Description: Parents of girls aged 9-14yearsold will undergo an interview to determine their knowledge, attitudes and beliefs concerning HPV vaccination
Study: NCT05327478

Intervention type: PROCEDURE
Intervention: NRP
Description: Normothermic Regional Perfusion

Intervention type: PROCEDURE
Intervention: NRP
Description: Normothermic Regional Perfusion

Intervention type: PROCEDURE
Intervention: DHOPE
Description: Dual Hypothermic Oxygenated Perfusion

Intervention type: PROCEDURE
Intervention: DHOPE
Description: Dual Hypothermic Oxygenated Perfusion

Intervention type: PROCEDURE
Intervention: COR-NMP
Description: Controlled Oxygenated Rewarming Normothermic Machine Perfusion
Study: NCT04918940

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Determination of COVID-19 vacciantion efficacy
Description: Samples will be taken after each vaccine injection to perform Sars-Cov-2 serology and Elispot interferon gamma and 3 months after the first vaccine injection
Study: NCT05466448

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RZL-012
Description: concentration of injected formulation 50 mg/mL RZL-012 of 7.5 mg/0.15 mL/injection point that results in a maximum total dose/volume of 240±30 mg/4.8±0.6 mL RZL-012
Study: NCT05006807

Intervention type: DEVICE
Intervention: Mechanomyograph Twitch Monitor
Description: Measurement of train-of-four count and ratio and post tetanic count

Intervention type: DEVICE
Intervention: Stimpod Twitch Monitor
Description: Measurement of train-of-four count and ratio and post tetanic count

Intervention type: DEVICE
Intervention: TetraGraph Twitch Monitor
Description: Measurement of train-of-four count and ratio and post titanic count

Intervention type: DEVICE
Intervention: TwitchView Twitch Monitor
Description: Measurement of train-of-four count and ratio and post tetanic count

Intervention type: DEVICE
Intervention: Nihon Kohden Twitch Monitor
Description: Measurement of train-of-four count and ratio and post tetanic count

Intervention type: OTHER
Intervention: Palpation of twitch count
Description: The train-of-four count is determined by manual palpation of the evoked twitch response
Study: NCT04713358

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nalmefene
Description: Immediately Intravenous injection of Nalmefene (0.25 g/kg, plus normal saline to 1ml) after surgery

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal Saline
Description: Immediately Intravenous injection of normal saline 1ml after surgery
Study: NCT06430749

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microtaze
Description: Targeted Microwave Tissue Coagulation
Study: NCT04992832

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: human umbilical cord mesenchymal stem cells
Description: Human umbilical cord mesenchymal stem cells were peripheral intravenous infused to experimental group.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: human serum albumin
Description: Saline solution containing 1 percent human serum albumin will be infused to the control group.
Study: NCT05255562

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Combined Serratus Anterior Plane Block
Description: Combined deep and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic Paravertebral Block
Description: Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.
Study: NCT05857202

Intervention type: DRUG
Intervention: Analgesics, Opioid
Description: Drugs were given immediately after the surgery, and correlation between analgesic use and parameters of oxidative stress and inflammation was assessed.

Intervention type: DRUG
Intervention: Analgesics, Opioid
Description: Drugs were given immediately after the surgery, and correlation between analgesic use and parameters of oxidative stress and inflammation was assessed.

Intervention type: DRUG
Intervention: Analgesics, Non-Narcotic
Description: Drugs were given immediately after the surgery, and correlation between analgesic use and parameters of oxidative stress and inflammation was assessed.

Intervention type: DRUG
Intervention: Analgesics, Non-Narcotic
Description: Drugs were given immediately after the surgery, and correlation between analgesic use and parameters of oxidative stress and inflammation was assessed.
Study: NCT05404854

Intervention type: OTHER
Intervention: Physical Activity
Description: wearing an accelerometer for 7 days before and after the rehabilitation program

Intervention type: OTHER
Intervention: sedentarity
Description: wearing an accelerometer for 7 days before and after the rehabilitation program

Intervention type: OTHER
Intervention: Measurement of explicit motivation
Description: Explicit motivation will be assessed using self-report questionnaires. Explicit attitudes using a 7-point bipolar response scale, participants will be asked to indicate for each of the 4 pairs of positive and negative adjectives used how much they associate them with regular PA and sedentary behaviors, respectively. Perceived behavioral control using a 7-point bipolar response scale, patients will be asked to indicate how well they felt they were able to engage in regular PA, and limit their sedentary behaviors, respectively, based on two items. Intentions using a 7-point bipolar response scale, patients will be asked to indicate how much they intend to adopt regular physical activity, and limit their sedentary behaviors, respectively, according to two items. Fears and beliefs related to physical activity and work will be measured by the FABQ in its French version

Intervention type: OTHER
Intervention: Measurement of implicit attitudes
Description: Implicit attitudes will be assessed by administering an Implicit Association Test on physical and sedentary activities. Sitting in front of a computer, participants will see a series of words appear in the middle of the screen referring to 4 conceptual categories - located at the top of the screen. Two represent the targeted behaviours (here, physical activity versus sedentary lifestyle) while the remaining two represent attributes (here, positive versus negative adjectives). The adjectives used will be the same as those used to measure explicit attitudes. The instructions given to the participant are to classify the words as quickly as possible, according to the semantic category to which they belong
Study: NCT05182229

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home-based (a hybrid model) CDT
Description: Participants will be provided therapist-administered, in person complete decongestive therapy (CDT) two times per week for two weeks (4 sessions), followed by real-time, virtual CDT consultations two times per week for three weeks (7 sessions) and one in person follow-up visit.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Clinic-based CDT
Description: Participants will be provided therapist administered, in-person CDT two times per week for six weeks (12 sessions).
Study: NCT05652868

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MYTX-011
Description: MYTX-011 will be administered as an intravenous infusion every 21 days.
Study: NCT05669248

Intervention type: DIAGNOSTIC_TEST
Intervention: mid covid-19 patients
Description: Collect the patient's whole blood for testing
Study: NCT05458232

Intervention type: DRUG
Intervention: Tadalafil 5mg
Description: Subjects will ingest one 5mg tablet of tadalafil each evening for 14 days.
Study: NCT04953637

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy
Description: Participants in the physiotherapy group will receive gait and balance focused physiotherapy at One Step Ahead Mobility physiotherapy clinic for 1-hour per day, 3 times/week for 8 weeks.
Study: NCT05983367

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ompenaclid
Description: Ompenaclid (RGX-202-01)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Bevacizumab
Description: Bevacizumab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOLFIRI regimen
Description: FOLFIRI regimen (irinotecan 180 mg/m2 over 90 minutes concurrently with folinic acid 400 mg/m2 over 2 hours, and then 5-FU 2400 mg/m2 over 46 hours on Days 1 and 15 of each 28-day cycle)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: FOLFIRI regimen
Description: FOLFIRI regimen (irinotecan 180 mg/m2 over 90 minutes concurrently with folinic acid 400 mg/m2 over 2 hours, and then 5-FU 2400 mg/m2 over 46 hours on Days 1 and 15 of each 28-day cycle)
Study: NCT05361018

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Whole Body Vibration exercise - WBV
Description: participants will be randomised to two different training interventions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole Body Vibration exercise - WBV
Description: participants will be randomised to two different training interventions
Study: NCT05895175

Intervention type: OTHER
Intervention: Questionnaires
Description: Questionnaires

Intervention type: OTHER
Intervention: Questionnaires
Description: Questionnaires
Study: NCT05801523

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: laparoscopic ethanol sclerotherapy
Description: ethanol (96%) sclerapy of endometrioma - endometrioma is filled with ethanol via foley catether, left for 10 min and than aspirated, endometrioma is washed with saline

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: laparoscopic cystectomy of endometrioma
Description: cystectomy of endometrioma - removal of endometrioma from ovary surgically
Study: NCT04766424

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep extension intervention
Description: Participants will receive a fitbit and 8 weekly sleep-related educational materials via email and telephone coaching to review their sleep tracker data, set goals, trouble shoot any problems, and increase motivation.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Health education
Description: Participants will receive 8 weekly health education newsletters delivered via email.
Study: NCT06478199

Intervention type: DIAGNOSTIC_TEST
Intervention: semen analysis
Description: lab invesigation

Intervention type: DIAGNOSTIC_TEST
Intervention: semen analysis
Description: lab invesigation
Study: NCT06407479

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: proprioceptive neuromuscular facilitation technique group
Description: Proprioceptive Neuromuscular Facilitation Technique group; In addition to the exercises applied to the participants and the control group, combined isotonic contractions and dynamic stabilization will be used as facilitation techniques, and hold-relax technique will be used as an inhibition technique.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eccentric muscle training technique application group
Description: Eccentric Muscle Training Technique: Participants will receive eccentric muscle training in addition to the exercises given to the control group. Before the application, 5-minute warm-up exercises will be given to the neck area. Eccentric muscle training will be applied to the muscles of the participants in the cervical region. Eccentric exercise will be strengthened in the cervical region muscles in the direction of movement in each plane, that is, flexion / extension and lateral flexion. The movements will first be explained and demonstrated to the patient.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: No intervention will be made.
Study: NCT05474651

Intervention type: OTHER
Intervention: Questionnaires set
Description: Participants will be asked to respond to the demographic information sheet, characteristics of smoking sheet, the Fagerstrom Test of Nicotine Dependence,Smoking Self-efficacy Questionnaire, Cigarette Withdrawal Scale, smoking hazard questionnaire, motivation to quit smoking sheet, ability to quit smoking sheet, alcohol consumption, International Physical Activity Questionnaire.
Study: NCT06255210

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine+Cisplatin(GP); Cyclophosphamide+Etoposide+Cisplatin(CEP)
Description: When the Ki67% index of the tumor is ≥ 25%, patients were treated with the GP regimen for induction chemotherapy; When the Ki67% index of the tumor is \< 25%, patients were treated with the CEP regimen for induction chemotherapy.
Study: NCT05065671

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tolcapone 100 MG
Description: Tolcapone 100 mg by mouth once

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Duloxetine 20 MG
Description: Duloxetine 20 mg by mouth once
Study: NCT05857540

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Plyometric and strengthening exercises
Description: Each session includes 2 upper-extremity plyometric exercises in bodyweight or with weight ball for 15-20 minutes and 4-5 strengthening exercises with band, dumbbell or barbell for 30-35 minutes. The difficulty of the movement protocol will increase weekly. They will be trained 2 times per week for 6 weeks with an average duration of 50 min per session.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Strengthening exercise
Description: Each session includes 5 upper-extremity strengthening exercises with band, dumbbell or barbell for 50 minutes. The difficulty of the movement protocol will increase weekly. They will be trained 2 times per week for 6 weeks with an average duration of 50 min per session.
Study: NCT05734807

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nucleoside/nucleotide reverse transcriptase inhibitors (NrtIs)
Description: Subjects will receive NrtIs therapy for 24 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HH-003 and NrtIs
Description: Subjects will receive HH-003 20 mg/kg intravenously Q2W and NrtIs therapy for 24 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HH-003, NrtIs and PEG-IFN-α
Description: Subjects will receive HH-003 20 mg/kg intravenously Q2W, NrtIs therapy and PEG-IFN-α 180μg SC QW for 24 weeks.
Study: NCT06321393

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 7-week Core stabilization exercise with abdominal drawing-in maneuver technique
Description: A 7-week core stabilization exercise with abdominal drawing-in maneuver technique consists of 2 stages, including the first stage (week 1-2) and the second stage (week 3-7) consisting of exercise program for 20-minute sessions with 3 sessions per week for 7 weeks. These exercise program will be provided to the participants via a weekly video call with the main researcher as a telerehabilitation program.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 7-week Core stabilization exercise with abdominal drawing-in maneuver technique
Description: A 7-week core stabilization exercise with abdominal drawing-in maneuver technique consists of 2 stages, including the first stage (week 1-2) and the second stage (week 3-7) consisting of exercise program for 20-minute sessions with 3 sessions per week for 7 weeks. These exercise program will be provided to the participants via a weekly video call with the main researcher as a telerehabilitation program.
Study: NCT05168566

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sutetinib Maleate Capsule
Description: Study drug to be taken orally with or without food (with food preferred) for up to13 cycles
Study: NCT05594589

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lemborexant
Description: Lemborexant oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lemborexant
Description: Lemborexant oral tablet.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: PBO
Description: Lemborexant-matched PBO tablet.
Study: NCT05212935

Intervention type: BIOLOGICAL
Intervention: Rotavirus Vaccine
Description: administration of the 3 doses of Rotavirus human bovine pentavalent reassortant vaccine
Study: NCT05334511

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional Electrical Stimulation
Description: functional electrical stimulation with Frequency 20 pps with Pulse width of 300 msec.
Study: NCT05603663

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Informing study subjects about their high CVD polygenic risk score
Description: During a visit, the family physician will announce the value of the subject's polygenic risk for CVD (either at the start or end of the trial, depending on the group) and discuss what it means, calculate the subject's overall risk for CVD using the Kardiokompass tool, advise the subject on weight loss and physical activity, and, if necessary, commence preventive treatment. Between visits, a mobile application will be utilized to collect data about the subjects' level of physical activity and body weight as well as to send reminders to the subjects every two weeks regarding exercise and healthy lifestyle choices.
Study: NCT06336759

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Restylane Defyne
Description: Twenty (20) subjects with thin skin will be recruited and treated with Restylane Defyne.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Restylane Lyft
Description: Twenty (20) subjects with thick skin will be recruited and treated with Restylane Lyft.