TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05407038

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT06385054

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: Participants will be taking 1 sachet a day, at a similar time every day, dissolved in 10 ml of lukewarm water.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be taking 1 sachet a day, at a similar time every day, dissolved in 10 ml of lukewarm water.
Study: NCT06297382

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ChatGPT Based Nursing Process Training
Description: ChatGPT Based Nursing Process Training topics:~Lesson 1: Use of artificial intelligence and ChatGPT in healthcare Lesson 2: Using ChatGPT in determining nursing diagnoses and goals Lesson 3: Using ChatGPT to determine nursing interventions Lesson 4: Things to consider and ethical principles when using ChatGPT when creating a nursing process.
Study: NCT05705427

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tenofovir Disoproxil Fumarate 300 MG
Description: Pregnant women in the experimental arm will receive TDF daily beginning in the 3rd trimester of pregnancy and continuing through 1 month postpartum.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Hepatitis B monovalent vaccine
Description: All infants born to women in the study will receive a birth-dose hepatitis B vaccine.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Hepatitis B monovalent vaccine
Description: All infants born to women in the study will receive a birth-dose hepatitis B vaccine.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pregnant women in the placebo arm will receive a placebo pill daily beginning in the 3rd trimester of pregnancy and continuing through 1 month postpartum.
Study: NCT05310812

Intervention type: DIAGNOSTIC_TEST
Intervention: Biochemical evaluation.
Description: Blood will be taken for biochemical evaluation-ELISA.

Intervention type: DIAGNOSTIC_TEST
Intervention: Biochemical evaluation.
Description: Blood will be taken for biochemical evaluation-ELISA.
Study: NCT05809492

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: step test
Description: The step speed of 18 steps/min was chosen for the first level because it is suitable for all subjects and prevents them from being too fast at the end of the test.~the slow standardized initial tempo at Level 1 of 72 beats/min allowed familiarity with the coordinated cascading technology of the tests (step up and down in time with the metronome beat). Regular replacement of the leading leg was encouraged to prevent unilateral leg fatigue and November muscle pain.~pwCF selected 1-minute stage times for each level in accordance with the maximum exercise test (CPET) recommendations in 18; at each new level, the test speed was increased by two steps / minute to ensure a progressive change in exercise parameters; a suitable end test time of 16 minutes was achieved along with an initial speed of 18 steps/min. The fast pace of 194 beats/min (48 steps/min at Level 16), which was eventually reached, it was physically possible to perform safely.
Study: NCT06181513

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Probiotic Blend Capsule
Description: 20 million CFU (Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus helveticus, Bifidobacterium breve)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Probiotic Blend Capsule
Description: 20 million CFU (Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus helveticus, Bifidobacterium breve)
Study: NCT05067816

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Med-South Lifestyle Program
Description: The Med-South Lifestyle Program (MSLP) is an evidence-based behavior change intervention that translates the PREDIMED (Mediterranean) dietary pattern for a southeastern US population and includes support for increased physical activity. To promote healthy dietary intake and increased physical activity, the intervention incorporates theory-based behavioral approaches targeting self-efficacy, self-regulation, and internal motivation. The MSLP is delivered in 4 monthly counseling sessions with 3 interim phone follow-up contacts. A maintenance phase lasting 6 months follows the 4-month MSLP and includes 2 phone contacts about 2 months apart. Participants are counseled individually, with 2 in-person counseling visits (at the 1st and 4th counseling visit) and 5 total phone contacts. Each participant is provided with program materials in a participant manual, a cookbook, and a local resource manual identifying community resources to support making targeted behavior changes.
Study: NCT05516355

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Compassion Cultivation Training
Description: The CCT is an 8-week standardized program (Jinpa, 2010; Jazaieri et al. 2013, 2014) consisting of daily formal and informal practices.~Training will be conducted during 3 days of the retreat (same schedule as the MBSR training). The CCT consists of six sequential steps: 1) Settling the mind and learn how to focus it; 2) Loving kindness and compassion for a loved one practice; 3) Loving kindness and compassion for oneself practice; 4) compassion toward others, embracing shared common humanity and developing appreciation of others; 5) compassion toward others including all beings; and 6) active compassion practices (Tonglen) which involve explicit evocation of the altruistic wish to do something about others' suffering. CCT program is delivered by certified instructors by the University of Stanford Centre for Compassion and Altruism Research and Education (http://ccare.stanford.edu/).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Compassion Cultivation Training
Description: The CCT is an 8-week standardized program (Jinpa, 2010; Jazaieri et al. 2013, 2014) consisting of daily formal and informal practices.~Training will be conducted during 3 days of the retreat (same schedule as the MBSR training). The CCT consists of six sequential steps: 1) Settling the mind and learn how to focus it; 2) Loving kindness and compassion for a loved one practice; 3) Loving kindness and compassion for oneself practice; 4) compassion toward others, embracing shared common humanity and developing appreciation of others; 5) compassion toward others including all beings; and 6) active compassion practices (Tonglen) which involve explicit evocation of the altruistic wish to do something about others' suffering. CCT program is delivered by certified instructors by the University of Stanford Centre for Compassion and Altruism Research and Education (http://ccare.stanford.edu/).
Study: NCT05809492

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: step test
Description: The step speed of 18 steps/min was chosen for the first level because it is suitable for all subjects and prevents them from being too fast at the end of the test.~the slow standardized initial tempo at Level 1 of 72 beats/min allowed familiarity with the coordinated cascading technology of the tests (step up and down in time with the metronome beat). Regular replacement of the leading leg was encouraged to prevent unilateral leg fatigue and November muscle pain.~pwCF selected 1-minute stage times for each level in accordance with the maximum exercise test (CPET) recommendations in 18; at each new level, the test speed was increased by two steps / minute to ensure a progressive change in exercise parameters; a suitable end test time of 16 minutes was achieved along with an initial speed of 18 steps/min. The fast pace of 194 beats/min (48 steps/min at Level 16), which was eventually reached, it was physically possible to perform safely.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: step test
Description: The step speed of 18 steps/min was chosen for the first level because it is suitable for all subjects and prevents them from being too fast at the end of the test.~the slow standardized initial tempo at Level 1 of 72 beats/min allowed familiarity with the coordinated cascading technology of the tests (step up and down in time with the metronome beat). Regular replacement of the leading leg was encouraged to prevent unilateral leg fatigue and November muscle pain.~pwCF selected 1-minute stage times for each level in accordance with the maximum exercise test (CPET) recommendations in 18; at each new level, the test speed was increased by two steps / minute to ensure a progressive change in exercise parameters; a suitable end test time of 16 minutes was achieved along with an initial speed of 18 steps/min. The fast pace of 194 beats/min (48 steps/min at Level 16), which was eventually reached, it was physically possible to perform safely.
Study: NCT05179733

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: six courses of zanubrutinib, rituximab and lenalidomide
Description: Patients in ZR2 group will receive 6 cycles of zanubrutinib 160mg bid, day 1-21, orally, lenalidomide 25mg qd, day 2-11, orally, rituximab 375mg/m², day 1, intravenously, every 21 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: six courses of rituximab combined with low-dose CHOP
Description: Patients in R-miniCHOP group will receive rituximab 375 mg/m² on day 1, cyclophosphamide 400 mg/m², doxorubicin 25 mg/m², and vincristine 1 mg on day 2, and prednisone 40 mg/m² on days 2-6, every 21 days.
Study: NCT05781438

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In-home standing and walking intervention
Description: Parents/legal guardians will be educated on and provided an activity booklet on intensive standing and walking play activities for their infant in a 9 by 9 foot body-weight support system (BWS). Activities include: squatting play at a couch or table, cruising along and between furniture, walking with a push toy or with one or two hands held, walking without support, and kicking and throwing a soft ball.~For 16 weeks, parents/legal guardians will be encouraged to implement the parent-led, intensive standing and walking intervention using BWS for at least 5 days/week for 30-60 min/day, with weekly telehealth calls and monthly home visits to coach parents in identifying key activities and progressing the program.
Study: NCT05471401

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Balloon-tipped catheter
Description: Gastric balloon
Study: NCT06290427

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DaVinci RAPN
Description: Robot-assisted Partial Nephrectomy with DaVinci® Surgical System

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hugo RAS RAPN
Description: Robot-assisted Partial Nephrectomy with Hugo™ RAS System
Study: NCT05391113

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MRI
Description: an fMRI measurement of the BOLD physiological signal for sensory responses

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: an fMRI measurement of the BOLD physiological signal for sensory responses

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: MRI
Description: an fMRI measurement of the BOLD physiological signal for sensory responses

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: EEG
Description: These tests, through videos with a social or non-social content (human presence or absence on the stereoscopic projection), will allow us to study two types of sensorialities (visual and interoceptive). Thus, it will be possible to obtain inter- and exteroceptive profiles of the participants, a direct reflection of the processing of the internal bodily sensations of the body.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: EEG
Description: These tests, through videos with a social or non-social content (human presence or absence on the stereoscopic projection), will allow us to study two types of sensorialities (visual and interoceptive). Thus, it will be possible to obtain inter- and exteroceptive profiles of the participants, a direct reflection of the processing of the internal bodily sensations of the body.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: EEG
Description: These tests, through videos with a social or non-social content (human presence or absence on the stereoscopic projection), will allow us to study two types of sensorialities (visual and interoceptive). Thus, it will be possible to obtain inter- and exteroceptive profiles of the participants, a direct reflection of the processing of the internal bodily sensations of the body.
Study: NCT06439251

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Group 1
Description: The treatment included TENS therapy, hot pack application, stretching exercises, isometric strengthening, straight leg raises with traction, and tibial gliding techniques. Participants in Group A also received Phonophoresis as an experimental technique.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Group 2
Description: The treatment included routine physiotherapy with TENS, hot pack application, stretching exercises, isometric strengthening, straight leg raises with traction, and tibial gliding techniques.
Study: NCT06021028

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: complex proximal carious cavities in posterior teeth.
Description: Selective enamel etching with 37% phosphoric acid for 30 second will be done then the bonding agent will be applied following the manufacturer's instructions.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: complex proximal carious cavities in posterior teeth.
Description: Selective enamel etching with 37% phosphoric acid for 30 second will be done then the bonding agent will be applied following the manufacturer's instructions.
Study: NCT05844852

Intervention type: DEVICE
Group type: OTHER
Intervention: P200TE
Description: The P200TE provides OCT imaging including retinatopography and ONH (optic nerve head) scans.
Study: NCT05067816

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Med-South Lifestyle Program
Description: The Med-South Lifestyle Program (MSLP) is an evidence-based behavior change intervention that translates the PREDIMED (Mediterranean) dietary pattern for a southeastern US population and includes support for increased physical activity. To promote healthy dietary intake and increased physical activity, the intervention incorporates theory-based behavioral approaches targeting self-efficacy, self-regulation, and internal motivation. The MSLP is delivered in 4 monthly counseling sessions with 3 interim phone follow-up contacts. A maintenance phase lasting 6 months follows the 4-month MSLP and includes 2 phone contacts about 2 months apart. Participants are counseled individually, with 2 in-person counseling visits (at the 1st and 4th counseling visit) and 5 total phone contacts. Each participant is provided with program materials in a participant manual, a cookbook, and a local resource manual identifying community resources to support making targeted behavior changes.
Study: NCT05585970

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: procalcitonin
Description: The PCT level in healthy individual without infection is below the limit of detection (0.01 ng/mL), and it is significantly elevated under the stimulation of pathogens

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: procalcitonin
Description: The PCT level in healthy individual without infection is below the limit of detection (0.01 ng/mL), and it is significantly elevated under the stimulation of pathogens

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: procalcitonin
Description: The PCT level in healthy individual without infection is below the limit of detection (0.01 ng/mL), and it is significantly elevated under the stimulation of pathogens
Study: NCT05567029

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risankizumab Dose A
Description: Prefilled Syringe

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risankizumab Dose B
Description: Prefilled Syringe
Study: NCT06031974

Intervention type: BEHAVIORAL
Intervention: DISCO Intervention
Description: optimal medical management in accordance with European Society of Cardiology recommendations + dietary intervention based on Dietary Approaches to Stop Hypertension (DASH diet) + strict monitoring of eating and lifestyle behaviors
Study: NCT04624321

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health and lifestyle tool
Description: Health and lifestyle tool used online

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Usual care
Description: Usual care at ordinary healthcare provider
Study: NCT05634161

Intervention type: OTHER
Intervention: Cognitive improvement software
Description: Cognitive improvement software
Study: NCT06464666

Intervention type: PROCEDURE
Intervention: Renal interlobar artery US
Description: By using convex US transducer, first find interlobar artery. Then get a pulsed wave doppler at renal interlobar artery for similar 3 to 5 waveforms. Measure peak systolic and minimum diastolic velocity and calculate RRI value.

Intervention type: PROCEDURE
Intervention: Renal inter-lobular artery US
Description: By using convex US transducer, first find interlobar artery. Then get a pulsed wave doppler at renal interlobar artery for similar 3 to 5 waveforms. Measure peak systolic and minimum diastolic velocity and calculate RRI value.
Study: NCT05751330

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transcatheter ablation of cardiac ganglionated plexi
Description: The ablative procedure involves applying radiofrequency deliveries in the two~Right atrium anatomical sites close to the two main ganglionic plexuses of the right atrium:~* Inferior-posterior area (site of first ablation) corresponding to the right inferior atrial ganglion located between the inferior vena cava, coronary sinus ostium and near the atrioventricular node~* Upper-posterior area (site of second ablation) corresponding to the right superior atrial ganglion located between the superior vena cava and the posterior surface of the right atrium
Study: NCT05851183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitis Vinifera seed extract medication plus therapeutic lifestyle change
Description: Administer 150mg of Vitis Vinifera seed extract (Entelon®) orally twice a day

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic lifestyle change only
Description: Implementing TLCs is a critical component of a comprehensive treatment plan for varicose veins. A key aspect of TLCs is the optimization of postural habits. Patients are advised to avoid extended sitting or standing periods, which exert additional pressure on the venous system in the lower extremities and exacerbate venous insufficiency. During rest periods, elevating the legs closer to the heart is recommended because this simple yet effective adjustment promotes venous return and reduces the gravitational burden on the venous valves of the legs. The use of graduated compression stockings during waking hours is another therapeutic lifestyle intervention that is often prescribed for patients with varicose veins. Additional TLCs include maintaining optimal body weight and engaging in regular physical exercise Walking or cycling are often recommended because of their effectiveness in promoting lower limb venous return.
Study: NCT06343064

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vebreltinib
Description: Phase Ib is a dose escalation study, the initial dose of Vebreltinib is 100mg/150mg/200mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vebreltinib
Description: Phase Ib is a dose escalation study, the initial dose of Vebreltinib is 100mg/150mg/200mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vebreltinib
Description: Phase Ib is a dose escalation study, the initial dose of Vebreltinib is 100mg/150mg/200mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vebreltinib
Description: Phase Ib is a dose escalation study, the initial dose of Vebreltinib is 100mg/150mg/200mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PLB1004
Description: Phase Ib is a dose escalation study, the initial dose of PLB1004 is 80mg/160mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PLB1004
Description: Phase Ib is a dose escalation study, the initial dose of PLB1004 is 80mg/160mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PLB1004
Description: Phase Ib is a dose escalation study, the initial dose of PLB1004 is 80mg/160mg,according to the result of Phase Ib, will confirm the RP2D.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PLB1004
Description: Phase Ib is a dose escalation study, the initial dose of PLB1004 is 80mg/160mg,according to the result of Phase Ib, will confirm the RP2D.
Study: NCT05686265

Intervention type: DRUG
Intervention: Oxygen
Description: Physiological intervention consisting of 1 hour of mild hypoxia (PaO2 9-10 kPa), 1 hour of mild hyperoxia (PaO2 13-14 kPa), and in healthy subjects also 1 hour of an inspired oxygen fraction of 100%.

Intervention type: DRUG
Intervention: Oxygen
Description: Physiological intervention consisting of 1 hour of mild hypoxia (PaO2 9-10 kPa), 1 hour of mild hyperoxia (PaO2 13-14 kPa), and in healthy subjects also 1 hour of an inspired oxygen fraction of 100%.
Study: NCT05935839

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multispectral optoacoustic tomography
Description: Molecular Imaging of tissue changes using MSOT in macroangiopathy in diabetes. Dual imaging before and after physical stress.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multispectral optoacoustic tomography
Description: Molecular Imaging of tissue changes using MSOT in macroangiopathy in diabetes. Dual imaging before and after physical stress.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multispectral optoacoustic tomography
Description: Molecular Imaging of tissue changes using MSOT in macroangiopathy in diabetes. Dual imaging before and after physical stress.
Study: NCT04721990

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automatic Sound Management 3.0
Description: The investigational front-end features include those within Automatic Sound Management 3.0 (i.e., Ambient Noise and Transient-Noise Reduction, and Adaptive Intelligence). Automatic Sound Management 3.0 will be accessed in the MAESTRO system software. The investigational front-end features within Automatic Sound Management 3.0 will be programmed in the SONNET2EAS processor.