TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05902910

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LUNA-EMG Robot
Description: During phase B, patients will benefit from functional rehabilitation of their upper limbs and from 30mn of training assisted by the LUMA-EMG robot.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LUNA-EMG Robot
Description: During phase B, patients will benefit from functional rehabilitation of their upper limbs and from 30mn of training assisted by the LUMA-EMG robot.
Study: NCT05636748

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-GP1 PET/CT
Description: Patient will receive 1 18F-GP1 PET/CT

Intervention type: DIAGNOSTIC_TEST
Intervention: Agitated Contrast Echocardiogram
Description: Agitated saline and ultrasound contrast will be performed to assess for intracardiac shunts and left ventricular thrombus.

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI Head
Description: Where necessary, if the CT head is normal or the clinical diagnosis of a stroke is not definite, a research MRI head will be undertaken if this has not already been performed as part of standard care.

Intervention type: DIAGNOSTIC_TEST
Intervention: ECG Monitoring
Description: All patients who do not have evidence of atrial fibrillation or atrial flutter on their 12-lead ECG will undergo an ECG Holter monitor for up to 7 days. This will be part of their standard care. If this has not been arranged by the usual care team this will be performed as a research procedure.
Study: NCT06226740

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single Visit Non Surgical Root Canal Treatment Protocol
Description: The current study aimed to compare the effects of different obturation techniques on postoperative pain level and radiographic healing in non-surgical endodontic treatment applied in a single visit in teeth with single root canal and apical periodontitis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single Visit Non Surgical Root Canal Treatment Protocol
Description: The current study aimed to compare the effects of different obturation techniques on postoperative pain level and radiographic healing in non-surgical endodontic treatment applied in a single visit in teeth with single root canal and apical periodontitis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single Visit Non Surgical Root Canal Treatment Protocol
Description: The current study aimed to compare the effects of different obturation techniques on postoperative pain level and radiographic healing in non-surgical endodontic treatment applied in a single visit in teeth with single root canal and apical periodontitis.
Study: NCT05576259

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: oVRcome phone app with headset
Description: The intervention oVRcome is self-help VRET for social anxiety, that is delivered through a smartphone application (app) in combination with headset that holds the smartphone and uses 360º video. oVRcome includes 6 modules of psychoeducation, relaxation, mindfulness, cognitive techniques, exposure through VR, and a relapse prevention module which are aimed to be completed weekly.
Study: NCT06021171

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Partially hydrolyzed guar gum + bifidobacterium lactis
Description: Synbiotic Supplement: Contains 5 grams of prebiotic fiber (Sunfiber®) and 8 billion active probiotics (Bifidobacterium lactis).

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Partially hydrolyzed guar gum
Description: 5 g Partially hydrolyzed guar gum

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: 5 g Maltodextrin
Study: NCT04705129

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanubrutinib
Description: 160mg Bid, D1-21, po

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: 200mg, D1, ivgtt
Study: NCT06238518

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intravascular Lithotripsy
Description: The size of the IVL balloon catheter is selected in a 1:1 ratio to the distal reference vessel diameter. The balloon catheter is then inflated to 4 atm, and 10 impulses are delivered. Subsequently, the balloon is inflated to 8 atm and then deflated to re-establish blood flow. Up to 100 impulses can be delivered, and the balloon can be repositioned within the lesion. In cases involving multiple lesions with different reference vessel diameters, various sizes of IVL balloons may be employed. If the IVL balloon catheter is unable to pass through the lesion, pre-dilatation can be performed using a smaller diameter noncompliant balloon or rotational atherectomy.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional lesion preparation strategy
Description: Conventional lesion preparation strategy includes the use of Compliant, noncompliant, cutting, or scoring balloons, Excimer laser coronary atherectomy, or Rotational atherectomy at the discretion of the operator.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional lesion preparation strategy
Description: Conventional lesion preparation strategy includes the use of Compliant, noncompliant, cutting, or scoring balloons, Excimer laser coronary atherectomy, or Rotational atherectomy at the discretion of the operator.
Study: NCT05941728

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Avocado
Description: The intervention treatment will contain avocado

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oil + Fiber
Description: The active comparator will contain a snack with oils and fibers that mimic an avocado

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Average American Diet
Description: The sham comparator will contain foods/beverages that mimic a standard American Diet
Study: NCT04987736

Intervention type: DIAGNOSTIC_TEST
Intervention: RT-PCR
Description: COVID 19 diagonostic test
Study: NCT05111054

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Exercise
Description: Acute leg-based resistance exercise bout (3 sets performed to volitional failure on leg extension and leg curl machines)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Exercise
Description: Acute leg-based resistance exercise bout (3 sets performed to volitional failure on leg extension and leg curl machines)
Study: NCT06520800

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treatment and handling obesity-related comorbidities in adolescents through exercise
Description: Tailor-made, one-to-one, physical exercise program
Study: NCT05105451

Intervention type: OTHER
Intervention: Collecting clinical data, EGG，arterial blood gas data and venous blood sample
Description: Collecting clinical data(before induction of anesthesia and first day after surgery), EGG（first day after surgery），arterial blood gas data(before induction of anesthesia and first day after surgery) and venous blood sample （before induction of anesthesia and first day, third day and 7th day after surgery）

Intervention type: OTHER
Intervention: Collecting clinical data, EGG，arterial blood gas data and venous blood sample
Description: Collecting clinical data(before induction of anesthesia and first day after surgery), EGG（first day after surgery），arterial blood gas data(before induction of anesthesia and first day after surgery) and venous blood sample （before induction of anesthesia and first day, third day and 7th day after surgery）
Study: NCT06079541

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX003142 will be administered orally
Description: oral once

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX003142 will be administered orally
Description: oral once

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX003142 will be administered orally
Description: oral once

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo in Cohorts 1 to 7
Description: oral once

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo in 3 Cohorts
Description: oral once
Study: NCT05506579

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercises for knees, lower back, hip/groin and pelvic floor muscles in an expanded warm up program
Description: Rhythmic gymnastics clubs allocated to the intervention group will be visited by a physiotherapist (the PhD candidate), which will perform thorough teaching of coaches and gymnasts on how to perform the exercises in the expanded warm up program. During the same visit, before commencing PFMT, the gymnasts will have an individual session were a portable 2D ultrasound machine (GE Healthcare -Logiq e R7, GE\>12L-RS - 5-13 MHz Wideband Linear Probe) will be used to teach and assess ability to perform a correct PFM contraction. The probe is placed suprapubically and provides concurrent visible biofeedback of the PFM contraction. Adherence to the intervention will be registered weekly by the coach in a training diary and asked for as an additional question in the monthly OSTRC-H2 sent to the gymnasts. Reminders will be sent by phone to the coaches every week. To assure proper execution and motivation, the PhD candidate will perform one extra visit midterm.
Study: NCT05773729

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: BD211
Description: Genetically modified CD34+ autologous stem cells were transfused intravenously with single dosing.
Study: NCT04232358

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Corticosteroid injection
Description: Corticosteroid injections are administered ultrasound guided in the bursa adjacent to the achilles tendon insertion every 4 weeks until symptoms resolve with at maximum of 3 injections.
Study: NCT05361525

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: modified saldhana's technique
Description: tummy tuck with anatomic definition using liposuction

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Traditional abdominoplasty
Description: uses the traditional technique of abdominoplasty with liposuction with v-shaped dissection till the coastal margin
Study: NCT04897906

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education Group
Description: Mother care, newborn care and breastfeeding education will be provided to pregnant women in the third trimester of pregnancy.
Study: NCT05406076

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: oral motor therapy
Description: Rigorous Chinese language oral motor therapy, including treatment of oral perceptual disorders and treatment of oral motor disorders. The treatment follows three basic principles: a combination of basic training and specific treatment; a combination of self-help and assisted treatment; and a combination of exercises, cues, and stimulation techniques. 30-40 min/session, 1 session/day, 5 sessions/week.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: oral motor therapy
Description: Rigorous Chinese language oral motor therapy, including treatment of oral perceptual disorders and treatment of oral motor disorders. The treatment follows three basic principles: a combination of basic training and specific treatment; a combination of self-help and assisted treatment; and a combination of exercises, cues, and stimulation techniques. 30-40 min/session, 1 session/day, 5 sessions/week.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ABA
Description: The mainstream ASD intervention approach with evidence-based support is currently recognized worldwide. Treatment follows the operational core principles of ABA, which are to establish learning goals based on the child's ability level, design teaching situations and select reinforcers for them, change the child's behavior problems with operational constraints, and to eliminate or improve problem behaviors through appropriate interventions to shape new adaptive behaviors. The training time is at least 20 hours per week.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ABA
Description: The mainstream ASD intervention approach with evidence-based support is currently recognized worldwide. Treatment follows the operational core principles of ABA, which are to establish learning goals based on the child's ability level, design teaching situations and select reinforcers for them, change the child's behavior problems with operational constraints, and to eliminate or improve problem behaviors through appropriate interventions to shape new adaptive behaviors. The training time is at least 20 hours per week.
Study: NCT05727969

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine at a a rate of 0.5 μg/kg/hour will be infused with induction of anesthesia.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lactated Ringer
Description: Lactated ringer solution at a a rate of 0.5 μg/kg/hour will be infused with induction of anesthesia.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Hypospadias
Description: Children who will undergone hypospadias surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hypospadias
Description: Children who will undergone hypospadias surgery

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Surgical pleth index
Description: The SPI value will be measured using Datex-Ohmeda (GE Healthcare,Madison,WI 53707-7550 USA) monitoring system.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical pleth index
Description: The SPI value will be measured using Datex-Ohmeda (GE Healthcare,Madison,WI 53707-7550 USA) monitoring system.
Study: NCT04806217

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Theory of Mind
Description: Patients will be submitted to different neuropsychological tests used in routine and the non-verbal false belief task through in the Theory of Mind
Study: NCT06207331

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine 0.5 μg/kg
Description: Participants inhale the atomized 0.5 μg/kg dexmedetomidine in 2 ml of 0.9% saline.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine 1 μg/kg
Description: Participants inhale the atomized 1 μg/kg dexmedetomidine in 2 ml of 0.9% saline.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Participants inhale atomized 2 ml 0.9% saline.
Study: NCT04232358

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Local anesthesia injections
Description: Local anesthesia injections are administered ultrasound guided in the bursa adjacent to the achilles tendon insertion every 4 weeks until symptoms resolve with at maximum of 3 injections.
Study: NCT06473181

Intervention type: OTHER
Group type: OTHER
Intervention: Core stability exercises
Description: Exercises applied to trunk , pelvis and abdomen to improve ability to stand , walk and balance.
Study: NCT05698485

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cleansing Balm
Description: DermResults Cleansing Balm w/ Avocado Oil twice daily

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facial Serum
Description: DermResults Advanced Serum w/ Hyaluronic Acid twice daily

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moisturizer
Description: DermResults Advanced Moisturizer w/ Hyaluronic Acid twice daily
Study: NCT04906811

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AuraGen 1-2-3 with AuraClens system (BK190433)
Description: Fat grafting to the breast in patients undergoing an aesthetic procedure without a breast implant. Device used: AuraGen 1-2-3 with AuraClens system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Revolve System (K120902)
Description: Fat grafting to the breast in patients undergoing an aesthetic procedure without a breast implant. Device used: Revolve System
Study: NCT05584514

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sentence Stimulus
Description: The sentences are designed such that a specific target word is either (a) Plausible (normal), (b) a semantic pragmatic violation, or (c) a morpho-syntactic violation. Example: e.g., Every morning at breakfast, the boys would (A: EAT)/ (B.PLANT )/ (C. EATS ) eggs...

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auditory Noise
Description: The sentences will be presented either A) in quiet, or B) with speech- shaped stationary background noise presented 3dB below the speech.
Study: NCT05894109

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: zinc citrate 50 mg
Description: will take zinc citrate 4 days before and 1 week after botulinum toxin injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Microcrystalline Cellulose
Description: will take placebo 4 days before and 1 week after botulinum toxin injection
Study: NCT05686603

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece
Description: Picosecond laser is a novel technology characterized by ultra-short, picosecond pulse duration which can be effective for many skin conditions, such as pigmentation, photoaging and wrinkles reduction. When combined with micro-lens array (MLA) optics, high-intensity, micro-injury zones can be generated in the epidermis and dermis, causing optical breakdown of surrounding tissue and stimulating of dermal remodeling with mild side-effects. Previous studies had showed the picosecond lasers with MLA afforded better or similar clinical outcomes as well as fewer side-effects in treating acne scar than non-ablative lasers.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: a ablative fractional 2940-nm Er:YAG laser
Description: 2940-nm erbium yttrium aluminum garnet (Er:YAG) laser is one of the most commonly used treatments for atrophic acne scars, which can remove the damage tissue of the scars and allow collagen remodeling and re-epithelialization.
Study: NCT05542420

Intervention type: OTHER
Intervention: No treatment given
Description: The study will be based on data already recorded in the medical record
Study: NCT04243564

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Supraglottic device (SGD)
Description: Positioning of SGD as temporary ventilatory device before tracheal intubation
Study: NCT05208177

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1802＋camrelizumab + famitinib
Description: SHR-1802 for injection，q3w； Camrelizumab for injection, q3w; Famitinib malate capsules, qd.
Study: NCT05354180

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: navicular mobilization
Description: Plantar glide combined with rotation of navicular bone against the talus The glide will be given in 20 repetitions of 3 sets, for 5 days a week

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rigid tapping
Description: A non-elastic zinc oxide sports tape will be applied to patients. Patient will be advised to protect the tape from getting wet.~Tape will be changed on every 3rd day (48 hours) on Wednesday and Friday.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Navicular Mobilization and Rigid Taping
Description: Plantar glide combined with rotation of navicular bone against the talus The glide will be given in 20 repetitions of 3 sets, for 5 days a week.~A non-elastic zinc oxide sports tape will be applied to patients. Patient will be advised to protect the tape from getting wet.~Tape will be changed on every 3rd day (48 hours) on Wednesday and Friday.
Study: NCT06288997

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active transcranial alternating current stimulation
Description: Hi-tACS with a current level of 15mA with a patented frequency of 77.5Hz.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial alternating current stimulation
Description: The device for the sham group has the same appearance and technical settings as the one used in the active group, designed to produce similar sensations on the scalp, but without effective penetration of the electric field into the brain.
Study: NCT05714410

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: PHGG
Description: PHGG

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: PHGG
Description: PHGG
Study: NCT05893186

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep Brain Stimulation, STN
Description: DBS of the STN, within FDA-approved limits and labeling, for symptoms of PD

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GP Deep Brain Stimulation
Description: PD with GP DBS, within FDA-approved limits and labeling, for symptoms of PD.
Study: NCT06583876

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Coriofix System
Description: Treatment of functional mitral regurgitation by reducing the mitral valve annular area through ablation of the posterior annulus.
Study: NCT05804136

Intervention type: DEVICE
Group type: OTHER
Intervention: Duramesh
Description: Laparotomy closure with Duramesh

Intervention type: DEVICE
Group type: OTHER
Intervention: Polydioxanone suture
Description: Laparotomy closure with standard PDS
Study: NCT06122831

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ05105 Tablets
Description: TQ05105 Tablets is a Janus kinase 1 (JAK1) and Janus kinase 2 (JAK2) Inhibitor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3617 Capsules
Description: TQB3617 Capsules is a Bromodomain and Extra-Terminal (BET) Inhibitor
Study: NCT06166992

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1291583
Description: BI 1291583

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1291583
Description: BI 1291583

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-BI 1291583
Description: \[14C\]-BI 1291583

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-BI 1291583
Description: \[14C\]-BI 1291583