TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06054191

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dabrafenib + Trametinib
Description: Dabrafenib 150mg BID + Trametinib 2mg QD/（2 cycles）

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capmatinib
Description: Capmatinib 400mg BID/（2 cycles）
Study: NCT06156683

Intervention type: OTHER
Intervention: Multiple sclerosis disease modifying drug
Description: There is no treatment allocation. Women with multiple sclerosis with a recorded pregnancy outcome during the inclusion period will be recruited.

Intervention type: OTHER
Intervention: Multiple sclerosis disease modifying drug
Description: There is no treatment allocation. Women with multiple sclerosis with a recorded pregnancy outcome during the inclusion period will be recruited.

Intervention type: OTHER
Intervention: Multiple sclerosis disease modifying drug
Description: There is no treatment allocation. Women with multiple sclerosis with a recorded pregnancy outcome during the inclusion period will be recruited.
Study: NCT05725070

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 212Pb-NG001
Description: 212Pb-NG001 is a targeted alpha-emitting radiopharmaceutical conjugated to a PSMA targeting peptide.~Patients will receive an initial single 10 MBq dose IV to explore the imaging potential of 212Pb-NG001.
Study: NCT05194644

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine physical therapy+ Sensorimotor stimulation
Description: Gustatory, Tactile, Olfactory, Visual and Auditory Stimulation will be applied in sensory stimulation and in motor stimulation strengthening, Proprioceptive neuromuscular facilitation techniques, Balance exercises will be performed

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Routine physical therapy
Description: Active and passive Range of motion exercise of upper and lower limb, Transfer from bed to chair, Sit to stand practice

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine physical therapy
Description: Active and passive Range of motion exercise of upper and lower limb, Transfer from bed to chair, Sit to stand practice
Study: NCT06236477

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Personalized Music
Description: Music that is familiar to the child will be played via bluetooth speaker throughout their immediate perioperative care

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: No Music
Description: Participants will receive standard care without music.
Study: NCT05472467

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: 200mg IV Q3W. Every three weeks is a cycle

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: stereotactic body radiation therapy
Description: stereotactic body radiation therapy for Oligometastases 35Gy/5f(7.0Gy/f,5f per week)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Squamous carcinoma: docetaxel 60 mg/m2, d1 + cisplatin 25 mg/m2, d1-3 or carboplatin AUC=4-6 d1, 21 days for one cycle, up to 4 cycles.~Non-squamous carcinoma: pemetrexed 500 mg/m2, d1 + cisplatin 25 mg/m2, d1-3 or carboplatin AUC=4-6, d1,21 days for one cycle, up to 4 cycles.
Study: NCT05353049

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bathing technique based on Basale Stimulation
Description: The relaxing somatic modelling technique will be applied, framed within the concept of Basal Stimulation®. To do this, the user remains seated and the parts of the body that are not being washed at that moment are covered with a towel, favouring the preservation of the user's privacy. The user is lathered up with soft mittens previously moistened with lukewarm water and lathered up. This process shall be carried out starting from the shoulder in a proximal to distal direction on the upper limbs, lower limbs and trunk (taking into account the sagittal anatomical plane) and in a cephalic to caudal direction (taking into account the transverse anatomical plane).~Subsequently, rinsing is carried out following the same guidelines as described above, using moistened soft mittens. Finally, intimate hygiene is performed with a disposable soapy sponge and the soap is rinsed off again with moistened soft terrycloth mittens. Throughout the whole process, the activity is explained to the user.
Study: NCT06470113

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: simultaneous cognitive training with transcranial magnetic stimulation
Description: simultaneous cognitive training with transcranial magnetic stimulation can enhance the therapeutic effect and improve brain function non-invasively.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: simultaneous cognitive training with transcranial magnetic stimulation
Description: simultaneous cognitive training with transcranial magnetic stimulation can enhance the therapeutic effect and improve brain function non-invasively.
Study: NCT05182463

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon Alfa-2B
Description: Different usage of peginterferon Alfa-2B and/or Nucleos(t)ide analogs in arm/group descriptions are depended on the wishes of the patient and the advice of the attending doctor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon Alfa-2B
Description: Different usage of peginterferon Alfa-2B and/or Nucleos(t)ide analogs in arm/group descriptions are depended on the wishes of the patient and the advice of the attending doctor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon Alfa-2B
Description: Different usage of peginterferon Alfa-2B and/or Nucleos(t)ide analogs in arm/group descriptions are depended on the wishes of the patient and the advice of the attending doctor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon Alfa-2B
Description: Different usage of peginterferon Alfa-2B and/or Nucleos(t)ide analogs in arm/group descriptions are depended on the wishes of the patient and the advice of the attending doctor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nucleoside Analogs
Description: Nucleos(t)ide analogs refer to one of the first-line drugs, including ETV, TDF and TAF.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nucleoside Analogs
Description: Nucleos(t)ide analogs refer to one of the first-line drugs, including ETV, TDF and TAF.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nucleoside Analogs
Description: Nucleos(t)ide analogs refer to one of the first-line drugs, including ETV, TDF and TAF.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nucleoside Analogs
Description: Nucleos(t)ide analogs refer to one of the first-line drugs, including ETV, TDF and TAF.
Study: NCT06219265

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dance Therapy
Description: A single-centre prospective randomised controlled trial will be conducted with a minimum of 48 patients with severe mental disorder (SMD) who will be randomised into two groups, 1 intervention group receiving dance therapy (n=24) and 1 control group receiving no intervention or treatment (n=24).~In addition, there will be an intervention group of healthy people who will receive dance therapy (n=20).~All the tests, will be carried out with patients with SMD and only the EEG for healthy people, in order to determine their baseline state. The dance therapy program will last for 20 sessions over 10 weeks.~The 44 people in the two experimental groups will participate in a 10-week intervention program with 2 sessions per week in which they will work for 1 hour on memory, attention and executive functions through dance and movement, ending with 10 minutes of Mindfulness.~The 24 people in the control group will not receive any type of intervention.
Study: NCT05205122

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combined trabeculotomy-trabeculectomy with mitomycin C
Description: Combined trabeculotomy-trabeculectomy with mitomycin C Will be done in all cases
Study: NCT00013221

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Exercise
Study: NCT05373407

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aerobic exercise
Description: participants will perform different dosage of the same intervention, one group will perform moderate intensity and the other will perform low intensity aerobic training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aerobic exercise
Description: participants will perform different dosage of the same intervention, one group will perform moderate intensity and the other will perform low intensity aerobic training
Study: NCT06035913

Intervention type: DRUG
Intervention: Dihydroergot mesylate
Description: take medicine
Study: NCT05790369

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance training (New ankle machine training)
Description: A six week workout plan, the subjects receive on site or online guidance from professional coaches every two weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Resistance training (Elastic band training )
Description: A six week workout plan, the subjects receive on site or online guidance from professional coaches every two weeks.
Study: NCT05264922

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tisseel Injectable Product
Description: Fibrin glue will provide an inert, biocompatible, viscous substance able to remain within the Rotator Cuff (RC) defect rather than injecting SVF cells in saline.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tisseel Injectable Product
Description: Fibrin glue will provide an inert, biocompatible, viscous substance able to remain within the Rotator Cuff (RC) defect rather than injecting SVF cells in saline.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Stromal Vascular Fraction Cells
Description: Stromal Vascular Fraction cells are autologously harvested, processed and reinjected into the affected shoulder.
Study: NCT05027555

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multisensory training
Description: Multisensory training included marching on the foam with visual deprivation and treadmill training with visual deprivation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional training
Description: Conventional training included strengthening, balance training and gait training
Study: NCT05234307

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adenosine A2B Receptor Antagonist PBF-1129
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Correlative studies

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given IV
Study: NCT05166772

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Donafenib
Description: 200 mg BID，oral administration will start before the first HAIC treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 200 mg，Q3W，Intravenous infusion will performe before HAIC treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HAIC
Description: Q3W. The total number of HAIC treatments was determined by the investigator based on patient needs. Dose: Oxaliplatin 85 mg / m2 for 2h, Calcium folinate 400 mg / m2 for 2h, 5-FU 400 mg / m2 for 10min, followed by 5-FU 1200 mg / m2 for 23 hours);
Study: NCT05033782

Intervention type: OTHER
Intervention: questionnaire
Description: Each included patient will be given a paper questionnaire, with the following questions:~* Zip code of patient's iterative residences since 2018, as well as the zip code of residence at the time of the 2 confinements~* Occupational status~* Occurrence of COVID infection/date needed for hospitalization~* During the COVID-19 outbreak, did the patient: avoid seeing a doctor, avoid going to health care facilities, stop background treatment for MS. If yes to any of the questions, the reason, date and duration of the cessation will be asked.~Other sources of data will be used together:~Clinical data from the OFSEP registry Pollution data from approved air quality monitoring associations Data on the circulation of influenza and gastroenteritis, produced by Santé Publique France
Study: NCT05823675

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itolizumab
Description: Subjects will receive Itolizumab concomitant within 72 hours of systematic Corticosteroids.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itolizumab
Description: Subjects will receive Itolizumab concomitant within 72 hours of systematic Corticosteroids.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itolizumab
Description: Subjects will receive Itolizumab concomitant within 72 hours of systematic Corticosteroids.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itolizumab
Description: Subjects will receive Itolizumab concomitant within 72 hours of systematic Corticosteroids.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: Methylprednisolone will be taperred as required

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: Methylprednisolone will be taperred as required

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: Methylprednisolone will be taperred as required

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: Methylprednisolone will be taperred as required
Study: NCT06445946

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Individuals randomized to this arm will receive oral metformin tablets for their Gestational diabetes mellitus treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin
Description: Individuals randomized to this arm will receive injectable insulin for their Gestational diabetes mellitus treatment.
Study: NCT05018832

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AlloRx
Description: cultured allogeneic adult umbilical cord derived mesenchymal stem cells
Study: NCT01864499

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ultrasound measurement of variations in the diameter of the sheath of the optic nerve
Description: pre-and postoperative optic nerve and J2 and J5 for all patients

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ultrasound measurement of variations in the diameter of the sheath of the optic nerve
Description: pre-and postoperative optic nerve and J2 and J5 for all patients
Study: NCT06490913

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 1000mg/m2, bid, d1-d14，q3w，1cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: oxaliplatin
Description: 130mg/m2, ivgtt, d1，q3w，1cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: cetuximab 500mg/m2, q2w

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: 85mg/m2, d1,q2w

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin
Description: 400mg/m2, d1,q2w

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-FU
Description: 400mg/m2，d1,q2w
Study: NCT05710120

Intervention type: OTHER
Intervention: Hepatitis C Screening Alerts in CHORUS™
Description: ZS Associates developed a machine learning-based model that provides a numeric % chance of returning a positive hepatitis C test for a patient without diagnosed hepatitis C infection. The data used to develop the model included a US-based large scale data source including electronic medical records, medical claims, and pharmacy claims as well as social determinants of health identified from open-source data.~Clinical Health Outcomes Reporting \& Utilization Service (CHORUS™) is a web-based reporting solution that transforms electronic health record data into meaningful information for healthcare providers. CHORUS™ generates a weekly email report that alerts clinics to patients who have a scheduled appt in the coming week and may require attention. In the after period of this study, the alert will identify patients who are eligible to be screened for hepatitis C infection and provide the % chance of returning a positive hepatitis C infection test.

Intervention type: OTHER
Intervention: Standard of Care
Description: CHORUS™ is a service provided to participating clinics and has been used by AIDS Healthcare Foundation for normal healthcare operations for quality improvement and retention in care in recent years. NO alerts identifying patients who are eligible to be screening for hepatitis C infection will be disseminated.
Study: NCT05735691

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: High-Intensity Treadmill Training
Description: Participants will walk on a treadmill at a speed that produces 70-80% of age-adjusted heart rate reserve or a rating of perceived exertion of 17/20. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts, with 2-3 minutes rest between bouts.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: High-Intensity Treadmill Training
Description: Participants will walk on a treadmill at a speed that produces 70-80% of age-adjusted heart rate reserve or a rating of perceived exertion of 17/20. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts, with 2-3 minutes rest between bouts.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Treadmill Training with Perturbations
Description: Participants will walk on a treadmill and a perturbation of the treadmill will be produced every 20s. Perturbations will randomly occur in the forward, backward, right or left directions, with a perturbation size set to 80% of stability threshold. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts with 2-3 minutes rest between bouts.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Treadmill Training with Perturbations
Description: Participants will walk on a treadmill and a perturbation of the treadmill will be produced every 20s. Perturbations will randomly occur in the forward, backward, right or left directions, with a perturbation size set to 80% of stability threshold. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts with 2-3 minutes rest between bouts.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Treadmill Training
Description: Participants will walk on a treadmill at a speed that produces 30-40% of age-adjusted heart rate reserve. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts, with 2-3 minutes rest between bouts.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard Treadmill Training
Description: Participants will walk on a treadmill at a speed that produces 30-40% of age-adjusted heart rate reserve. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts, with 2-3 minutes rest between bouts.
Study: NCT05097703

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Resource
Description: The sleep resource is a card game to be played by children and caregivers as part of their bedtime routine. It includes exercises to help prepare the child for sleep, including deep breathing, mindfulness and light movement. Caregivers will be asked to use the resource for a minimum of three nights a week over a four week period, and complete pre and post outcome measures as well as sleep and resource use diaries for their children
Study: NCT06136377

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-PSMA-617 PET scan
Description: Patients then begin their first course of treatment an average of 2 months after the 68Ga-PSMA-11 PET scan, with IVR usually divided into a total of 6 courses. During the first course of treatment, patients undergo an initial SPECT scan 5h (±1h) post-injection, and return to the nuclear medicine department for three further SPECT scans, at 24h, 4 days and 8 days post-injection.
Study: NCT05019898

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: pupillometry
Description: Step 1: The triage will be carried out by the nurse. The nurse will then perform a self-assessment of the patient's pain using a simple verbal scale.~The nurse will then record the patient's self-assessment of his pain using the numeric scale for pain.~Step 2: Immediately after this first assessment, eligible patients will be approached by the study investigator to be included in the study.~Step 3: If the patient gives informed consent, the study investigator will perform~* The quantification of their anxiety~* An assessment of pain by a NeuroLight videopupillometer (iDmed, Marseille, France) using two dynamic tests, the Pupillary Unrest in Ambient Light (PUAL) and the pupillary light reflex.~Step 4: One hour after the triage, a second pain assessment will be performed. Step 5: The same pupillometry measurements will be taken immediately after the nurse has assessed the pain.
Study: NCT05233020

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: robotic
Description: fifteen patients undergo robotic operation

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: hybrid
Description: fifteen patients undergo hybrid operation
Study: NCT05513248

Intervention type: PROCEDURE
Intervention: anatomic lung resection
Description: includes minimally invasive or open lung segmentectomy, lobectomy, bilobectomy and pneumonectomy
Study: NCT04831489

Intervention type: RADIATION
Intervention: Imaging
Description: pre and postoperative CT scan of lung

Intervention type: RADIATION
Intervention: Imaging
Description: pre and postoperative CT scan of lung
Study: NCT05645497

Intervention type: PROCEDURE
Intervention: Surgery with FACET FIXATION implants
Description: Surgical treatment of degenerative lumbar spinal stenosis by lumbar decompression with FACET FIXATION implants

Intervention type: PROCEDURE
Intervention: Surgery with Pedicle Screw
Description: Surgical treatment of degenerative lumbar spinal stenosis by lumbar decompression with Pedicle Screw
Study: NCT06482736

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extracorporeal Shockwave Therapy
Description: Extracorporeal Shockwave Therapy could reduce the pain of myofascial pain syndrome by pain signal alteration, promoting angiogenesis and increasing perfusion in ischemic tissues induced by sensitization of nociceptors and muscle ischemia.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extracorporeal Shockwave Therapy
Description: Extracorporeal Shockwave Therapy could reduce the pain of myofascial pain syndrome by pain signal alteration, promoting angiogenesis and increasing perfusion in ischemic tissues induced by sensitization of nociceptors and muscle ischemia.
Study: NCT05877053

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CK-4021586
Description: CK-4021586

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CK-4021586
Description: CK-4021586

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CK-4021586
Description: CK-4021586

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for CK-4021586
Description: Placebo for CK-4021586

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for CK-4021586
Description: Placebo for CK-4021586