TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06423209

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strength training program
Description: Strength training program to be developed during 16 weeks. There will be 3 exercise sessions per week and those participants who perform at least 2 sessions during the program will be considered for the statistical analysis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strength training program
Description: Strength training program to be developed during 16 weeks. There will be 3 exercise sessions per week and those participants who perform at least 2 sessions during the program will be considered for the statistical analysis.
Study: NCT04862585

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ranitidine
Description: Given IV and/or PO
Study: NCT05525325

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: General Anesthesia
Description: Patients randomized to the GA arm are intubated after anesthetic induction. For this purpose, they are pre-oxygenated with an oxygen mask and non-invasive monitoring is established. After sufficient pre-oxygenation has been applied, analgesic and sedative medication are administered. If the patient is sufficiently long nil by mouth they are manually ventilated before a muscle relaxant is administered. A rapid-sequence induction is performed with administration of an opioid, sedative and muscle relaxant in rapid succession and without intermediate manual ventilation in non-nil by mouth patients. To secure the airway, an endotracheal tube is inserted into the trachea with the aid of a laryngoscope. After insertion of the endotracheal tube, its endotracheal position is confirmed with auscultation and capnography. GA maintenance therapy with opioids, sedatives and catecholamines, if needed, will then be started.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General Anesthesia
Description: Patients randomized to the GA arm are intubated after anesthetic induction. For this purpose, they are pre-oxygenated with an oxygen mask and non-invasive monitoring is established. After sufficient pre-oxygenation has been applied, analgesic and sedative medication are administered. If the patient is sufficiently long nil by mouth they are manually ventilated before a muscle relaxant is administered. A rapid-sequence induction is performed with administration of an opioid, sedative and muscle relaxant in rapid succession and without intermediate manual ventilation in non-nil by mouth patients. To secure the airway, an endotracheal tube is inserted into the trachea with the aid of a laryngoscope. After insertion of the endotracheal tube, its endotracheal position is confirmed with auscultation and capnography. GA maintenance therapy with opioids, sedatives and catecholamines, if needed, will then be started.
Study: NCT04796155

Intervention type: DIAGNOSTIC_TEST
Intervention: Intrapartum ultrasound
Description: Intrapartum ultrasound will be performed by suprapubic and transperineal approach for 30 seconds.
Study: NCT06388993

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Collection
Description: Comparing the two collection systems for bone marrow aspirate
Study: NCT05889065

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy
Description: group A will receive conventional physical therapy including~10~ultrasound(1.5w/cm2~,3 MHz continuous type, duration 10 minutes),hot packs (on affected region of shoulder for 10 minutes),shoulder ROM, stretching exercises, and joint mobilization five times per week for two weeks with 40 minutes duration of each session. Maitland mobilization will be given in supine position.~· After giving glenohumeral joint distraction, caudal, dorsal, and ventral glides will be given at a rate of 2-3 oscillation/second for 1 to 2 minutes to patients. Grade I or II rhythmic oscillations will be applied in free range.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional Physical Therapy
Description: group A will receive conventional physical therapy including~10~ultrasound(1.5w/cm2~,3 MHz continuous type, duration 10 minutes),hot packs (on affected region of shoulder for 10 minutes),shoulder ROM, stretching exercises, and joint mobilization five times per week for two weeks with 40 minutes duration of each session. Maitland mobilization will be given in supine position.~· After giving glenohumeral joint distraction, caudal, dorsal, and ventral glides will be given at a rate of 2-3 oscillation/second for 1 to 2 minutes to patients. Grade I or II rhythmic oscillations will be applied in free range.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PNF techniques
Description: In this group 20 repetitions of diagonal scapular pattern (anterior elevation and posterior depression, posterior elevation and anterior depression) with 20 seconds rest period will be given to subjects. PNF techniques of rhythmic initiation and repeated contractions will be used in all patterns, applied for 40 minutes.
Study: NCT05139433

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telepsychotherapy
Description: 5 weekly psychotherapy sessions that will cover the following contents: psychoeducation on stress responses, family communication, relaxation and mindful techniques, emotion recognition, management of irritability, behavioral activation and cognitive restructuring. The sessions will be implemented via the internet by a trained psychologist. Participants will also have access to the psychoeducational videos described at intervention 2

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychoeducational Videos
Description: 15 educational videos to be watched by the families. There will be one video about psychoeducation on stress responses, one about family communication, four about mindfulness and relaxation techniques, two about emotion recognition, one about management of irritability, one about behavioral activation, three about healthy routines, one about cognitive restructuring, and one about management of anxiety crisis.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychoeducational Videos
Description: 15 educational videos to be watched by the families. There will be one video about psychoeducation on stress responses, one about family communication, four about mindfulness and relaxation techniques, two about emotion recognition, one about management of irritability, one about behavioral activation, three about healthy routines, one about cognitive restructuring, and one about management of anxiety crisis.
Study: NCT06502431

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: phase contrast sequences
Description: patients will benefit from phase contrast sequences complementary to the morphological MRI performed as part of the patient management.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: phase contrast sequences
Description: patients will benefit from phase contrast sequences complementary to the morphological MRI performed as part of the patient management.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: phase contrast sequences
Description: patients will benefit from phase contrast sequences complementary to the morphological MRI performed as part of the patient management.
Study: NCT05958641

Intervention type: OTHER
Intervention: Questionnaires
Description: Participants will be asked to complete the questionnaire including general demographic information, the cognition, resistance and use of NPS as well as the behavioral expression of addiction susceptibility genes and adverse childhood experience.
Study: NCT06322953

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Direct-Acting Oral Anticoagulants (used as per local standard practice)
Description: Direct-acting oral anticoagulants to be prescribed as per local standard practice at either 1 or 4 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Direct-Acting Oral Anticoagulants (used as per local standard practice)
Description: Direct-acting oral anticoagulants to be prescribed as per local standard practice at either 1 or 4 weeks.
Study: NCT00729768

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: basiliximab
Description: 2 intravenous doses

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: basiliximab
Description: 2 intravenous doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: efalizumab
Description: Subcutaneous repeating dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mycophenolate mofetil
Description: Oral repeating dose

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: mycophenolate mofetil
Description: Oral repeating dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: corticosteroids
Description: Repeating doses

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: corticosteroids
Description: Repeating doses

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cyclosporine
Description: Oral repeating dose
Study: NCT04727853

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: irinotecan liposome injection
Description: Drug: irinotecan liposome injection
Study: NCT04647916

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sacituzumab Govitecan
Description: Given IV
Study: NCT06185647

Intervention type: OTHER
Intervention: No intervention. Observational retrospective study
Description: No intervention.
Study: NCT05780892

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Wellbeing
Description: Participants in this intervention will learn cognitive behavioral therapy tools to identify unhelpful beliefs and thought patterns, increase motivation through SMART goal making, and increase relaxation and stress management techniques through deep breathing, progressive muscle relaxation and pleasant activity scheduling. Additionally, participants will learn acceptance and commitment therapy tools to increase cognitive flexibility and resilience through acceptance and diffusion work, being present through contact with present moment and self as context and doing what matters through committed actions and value identification.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EHR Skills Optimization
Description: Participants in this intervention will learn how to better utilize the EHR by gaining knowledge and skills in the EHR. Session topics include, but are not limited to, understanding current usage patterns and behaviors in the EHR, optimization of the table of contents for easier chart navigation, integration of specialty-focused workflows with current EHR documentation and chart review tools, and recommendations to be more efficient and reduce amount of time spent in the EHR.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Performance Improvement
Description: This intervention focuses on improving participants perception of Keck Medicine as a positive workplace environment by supporting participants in gaining basic performance improvement knowledge and skills through didactic training, group discussions based on sociocultural learning theory, and hands on practice leading a performance improvement project. Sessions will review performance improvement concepts such as Lean wastes, systems thinking, change management and sustainability. Participants in this intervention will then identify a project area of focus that they want to improve and develop a project charter. Once a project area has been identified, participants will be put into breakout rooms to discuss successes and challenges as well as receive feedback on their project from peers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: Participants randomly assigned to the control condition will continue as usual care and will not complete any intervention during the duration of the study.
Study: NCT05261048

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic Proprioceptive neuromuscular facilitation in addition to Conventional Physical Therapy
Description: The experimental group received both conventional and Pelvic PNF for 30 minutes each, once in a day, 4 days per week. The experimental group will be given anterior elevation-Posterior depression pattern with the techniques of Rhythmic initiation, Slow reversal and Stabilizing reversal. These techniques will be given on affected side for total 30 minutes with 15 minutes of pelvic PNF in one session with rest periods in between. Participants will be positioned into side lying with both hip flexion 1000 and knee flexion 450, neck supported by a pillow with flexion of 300. Hand placement for anterior elevation over the crest of the ilium one hand overlaps other for posterior depression heel of the one hand hold with other hand on the ischial tuberosity.~Pull up and Push down command will be given along with the techniques of rhythmic initiation, slow reversal and stabilizing reversal.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Conventional Physical Therapy
Description: Conventional physiotherapy will be asked to perform truncal exercises in spine and sitting position for total 30 minutes including rest periods in between, once in a day for 4 days per week.~Exercises in supine position included (pelvic bridging, unilateral pelvic bridging, upper trunk rotation (clasped hand), lower trunk rotation (crook lying) with 3 repetitions for each exercise.~In sitting position, exercises included flexion and extension of lower trunk, rotation of upper and lower trunk, forward and lateral reach with 3 repetitions for each exercise.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physical Therapy
Description: Conventional physiotherapy will be asked to perform truncal exercises in spine and sitting position for total 30 minutes including rest periods in between, once in a day for 4 days per week.~Exercises in supine position included (pelvic bridging, unilateral pelvic bridging, upper trunk rotation (clasped hand), lower trunk rotation (crook lying) with 3 repetitions for each exercise.~In sitting position, exercises included flexion and extension of lower trunk, rotation of upper and lower trunk, forward and lateral reach with 3 repetitions for each exercise.
Study: NCT05386797

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Geniculate Artery Embolization
Description: The GAE procedure involves the use of an embolization agent to block blood flow to specific areas of the knee. Under sedo-analgesia, access to the target vessels is gained through the femoral or radial artery. GAE is performed with angiography to visualize blood vessels to assess the affected knee joint and ensure successful treatment.
Study: NCT05260515

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Staying Sharp intervention
Description: In the Staying Sharp online program, participants have the opportunity to select which health pillars they are most interested in improving (Be social, Engage your brain, Manage stress, Ongoing exercise, Restorative sleep, and Eat right). After selecting the health pillars, participants can set plans and goals. There are designated activities in each health pillar for participants to complete, including watch videos, read articles, or play games. Participants will follow a step-by-step guide to achieve these goals. The website tracks the status of these goals.~Participants will use Staying Sharp program for 4 months. Research staff will call participants to encourage participants to use the program. Right after the completion of the 4-month program, we will send out a survey to understand user experiences. We will follow participants for another 4 months. After 4 months follow-up, an exit study survey will be conducted either via videoconferences or in-person visits.
Study: NCT05056987

Intervention type: DEVICE
Group type: OTHER
Intervention: Lehfilcon A contact lenses
Description: CE-marked spherical soft contact lenses worn according to to the product package insert/Instructions for Use

Intervention type: DEVICE
Group type: OTHER
Intervention: Lehfilcon A contact lenses
Description: CE-marked spherical soft contact lenses worn according to to the product package insert/Instructions for Use

Intervention type: DEVICE
Group type: OTHER
Intervention: Senofilcon A contact lenses
Description: CE-marked spherical soft contact lenses worn according to to the product package insert/Instructions for Use

Intervention type: DEVICE
Group type: OTHER
Intervention: Senofilcon A contact lenses
Description: CE-marked spherical soft contact lenses worn according to to the product package insert/Instructions for Use

Intervention type: DEVICE
Group type: OTHER
Intervention: AOSEPT PLUS with HydraGlyde
Description: Hydrogen peroxide-based cleaning and disinfecting solution

Intervention type: DEVICE
Group type: OTHER
Intervention: AOSEPT PLUS with HydraGlyde
Description: Hydrogen peroxide-based cleaning and disinfecting solution
Study: NCT05247554

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxychloroquine + low-dose prednisone
Description: Hydroxychloroquine, tablets, 400mg/day for 6 months combined with Prednisone, 20mg/day for 1 month, then 10mg/day for 20 weeks (ie up to M6). The cumulative doses of prednisone during the 6 months of the study will be 1820mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisone
Description: prednisone, tablets, 40mg/day for 4 weeks, then 30mg/day for 2 weeks, then 20mg/day for 2 weeks, then 15mg/day for 2 weeks, then 10mg/day for 14 weeks (i.e. up to 6 months ).~The cumulative doses of prednisone during the 6 months of the study will be 2870mg
Study: NCT05402397

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Losartan Potassium
Description: Patients will receive losartan potassium for 30 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan Potassium
Description: Patients will receive losartan potassium for 30 days.
Study: NCT05727787

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiation Treatment
Description: Single fraction SBRT 27 Gy
Study: NCT05772494

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Assessment of activity limitations, SDO and DOA
Description: The assessment is made with two instruments (DOA, SDO), and finally the occupational therapist includes the analysis and summary of activity limitations to the sickness certificate. For comparative reasons the participant will answer to a sociodemographic questionnaire focusing on work situation and sick leave

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: All assessments concerning activity limitations are made using usual routines, primarily by the sick-listing physician. For comparative reasons the participant will answer to a sociodemographic questionnaire focusing on work situation and sick leave
Study: NCT04997759

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neostigmine and Sugammadex
Description: Compare both groups efficacy of reverse the neuromuscular blocking agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neostigmine and Sugammadex
Description: Compare both groups efficacy of reverse the neuromuscular blocking agent
Study: NCT05914441

Intervention type: OTHER
Intervention: Standard clinical practice
Description: The study will be carried out in the context of the usual clinical practice conditions, not imposing restrictions on the participating physician or influencing their normal clinical practice.
Study: NCT04825483

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Weight loss
Description: Participants will receive resources to support the weight loss program including a recipe book, activities book and how-to guide. The diet program comprises two phases: 1) intensive weight loss through a ketogenic Very Low Calorie Diet (VLCD), including meal replacements for two meals/day, and 2) transition from ketogenic VLCD onto a longer-term eating plan for weight maintenance. Meal replacements will be provided free of charge for up to 6 months. Participants will be encouraged to lose at least 10% body weight.
Study: NCT05839301

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational live attenuated varicella vaccine (lot 1)
Description: 0.5ml/vial

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational live attenuated varicella vaccine (lot 2)
Description: 0.5ml/vial

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational live attenuated varicella vaccine (lot 3)
Description: 0.5ml/vial
Study: NCT05039086

Intervention type: DRUG
Intervention: PDE5 inhibitor
Description: PDE5 inhibitors (sildenafil, tadalafil) claim is used as the exposure group.

Intervention type: DRUG
Intervention: Endothelin Receptor Antagonists
Description: Endothelin receptor antagonists (bosentan, ambrisentan, macitentan) claim is used as the reference group.
Study: NCT04825483

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Participants will receive resources to facilitate the physiotherapy management plan, including information about the video-conference platform, osteoarthritis information, an exercise plan/log book and a booklet of possible exercises. The physiotherapist consultations include a structured, progressive exercise and physical activity plan. Participants will be given exercise resistance bands and a ankle weight for home exercises.~Physiotherapists will choose from a list of exercises, aiming to prescribe 5-6 at once. Intensity is determined using a modified Rating of Perceived Exertion (RPE) scale, where it should feel hard to very hard to perform a full set of each exercises. Participants are encouraged to complete exercises three times per week. Physiotherapists encourage the participant to increase their general and incidental levels of physical/aerobic activity based on their individual needs and goals, as well as their current level of activity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants will receive resources to facilitate the physiotherapy management plan, including information about the video-conference platform, osteoarthritis information, an exercise plan/log book and a booklet of possible exercises. The physiotherapist consultations include a structured, progressive exercise and physical activity plan. Participants will be given exercise resistance bands and a ankle weight for home exercises.~Physiotherapists will choose from a list of exercises, aiming to prescribe 5-6 at once. Intensity is determined using a modified Rating of Perceived Exertion (RPE) scale, where it should feel hard to very hard to perform a full set of each exercises. Participants are encouraged to complete exercises three times per week. Physiotherapists encourage the participant to increase their general and incidental levels of physical/aerobic activity based on their individual needs and goals, as well as their current level of activity.
Study: NCT04779372

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: smartphone-based dCBT-I from a Wechat applet
Description: Participants will receive 6-week smartphone-based dCBT-I from a Wechat applet.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: sleep education
Description: Participants will receive sleep education like the advices getting from common sleep clinic.