TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06207565

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vestibular Flap Group
Description: Achieving the vestibular flap, a 1-cm long horizontal vestibular access incision using a 15c blade 3-4mm apical to the mucogingival junction of the hopeless tooth, exposing the alveolar bone. Flap dissection in a coronal direction to detach the periosteum is completed, forming a sub-periosteal tunnel.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Single Flap Approach group
Description: A modified envelope flap originally reported as an access flap for single implant insertion in areas of esthetic relevance will be performed. A sulcular incision on the labial aspect extending at least one tooth mesial and distal to the implant site (permitting enough accessibility for bone augmentation) is done. The flap is reflected by performing a split-thickness flap elevation starting from the interproximal incisions, leaving the anatomical papillae in situ. While the full-thickness flap elevation is performed on the labial aspect of the included surgical area, starting at the sulcus, and reaching at least 3 mm apical to the bone crest.
Study: NCT05018910

Intervention type: OTHER
Group type: OTHER
Intervention: Skin to Skin
Description: During routine Skin-to-skin sessions, the heart rate variability of the infant will be measured.
Study: NCT05722158

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Dietary supplementation with placebo.
Description: Volunteers will be provided with the placebo. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP1.
Description: Volunteers will be provided with the collagen-derived product CP1. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP2.
Description: Volunteers will be provided with the collagen-derived product CP2. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study: NCT06112912

Intervention type: OTHER
Intervention: REAL Essentials Advance
Description: REA is a relationship education curriculum developed by the Center for Relationship Education for high school-age youth. REA teaches youth critical relationship skills and practical approaches for navigating the social dynamics of friendship and love. The curriculum draws on several theories of behavior change, including social cognitive theory, theory of planned behavior, social inoculation theory, social norms theory, and behavior change theory.~REA includes 87 lessons organized into 10 units. The units cover topics such as healthy relationships, effective communication, commitment, planning for the future, job readiness, and sexual health.
Study: NCT04840368

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dancing
Description: Participants randomized to the dance group will take part in a dance intervention programme for 12 weeks, including 3 sessions per week (non-consecutive days), each lasting 60 min. Dance classes will be performed individually at home, guided by an expertise instructor, as live sessions online. They will include a variety of rhythms such as salsa, merengue, jazz dance, aerobics, etc. The dance sessions will include a warm up of approximately 10 min (posture, join mobility and dance technique), a main part of 40 min (practicing isolated dance moves and learning of specific choreographic routines), and a cool down of 10 min (muscle stretching and relaxation).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dancing
Description: Participants randomized to the dance group will take part in a dance intervention programme for 12 weeks, including 3 sessions per week (non-consecutive days), each lasting 60 min. Dance classes will be performed individually at home, guided by an expertise instructor, as live sessions online. They will include a variety of rhythms such as salsa, merengue, jazz dance, aerobics, etc. The dance sessions will include a warm up of approximately 10 min (posture, join mobility and dance technique), a main part of 40 min (practicing isolated dance moves and learning of specific choreographic routines), and a cool down of 10 min (muscle stretching and relaxation).
Study: NCT05700097

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dengzhanxixin Injection
Description: Experimental arms for low, and high dose for the standard protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dengzhanxixin Injection
Description: Experimental arms for low, and high dose for the standard protocol

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo injection
Description: placebo control arm for the standard protocol
Study: NCT06505902

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Exercise by bicycle and performing diffusing capacity measurements at the same time with arterial blood gasses.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Exercise by bicycle and performing diffusing capacity measurements at the same time with arterial blood gasses.
Study: NCT05004025

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Novocure Optune
Description: Novacure Optune with Opdivo and Yervoy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Opdivo
Description: Novacure Optune with Opdivo and Yervoy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Yervoy
Description: Novacure Optune with Opdivo and Yervoy
Study: NCT06264375

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: see group description

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: see group description
Study: NCT06028139

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Continuous glucose monitoring and health coaching
Description: Each CGM device will work for 14 days. The participants will use the CGM devices for the first two-week period in the first three months of the trial, and the first two-week period of the second three months of the trial.~Participants will interact with health coach throughout the study duration.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: EMPOWER mobile app
Description: Nudges will be delivered through the EMPOWER mobile app. Participants will log lifestyle information such as diet and physical activity, and clinical information such as medication and HbA1c levels through the EMPOWER mobile app.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EMPOWER mobile app
Description: Nudges will be delivered through the EMPOWER mobile app. Participants will log lifestyle information such as diet and physical activity, and clinical information such as medication and HbA1c levels through the EMPOWER mobile app.
Study: NCT06514274

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berberine
Description: Berberine 500 mg, twice daily for 14 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Vonoprazan 20 mg, twice daily for 14 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin
Description: Amoxicillin 1000mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: Amoxicillin 1000mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bismuth
Description: Bismuth 220mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clarithromycin
Description: Clarithromy 500mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Esomeprazole
Description: Esomeprazole 10mg, twice daily for 14 days.
Study: NCT05722158

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP3.
Description: Volunteers will be provided with the collagen-derived product CP3. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP4.
Description: Volunteers will be provided with the collagen-derived product CP4. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study: NCT05797051

Intervention type: DIAGNOSTIC_TEST
Intervention: Microscopic hyperspectral imaging system
Description: Microscopic hyperspectral imaging system

Intervention type: DIAGNOSTIC_TEST
Intervention: Microscopic hyperspectral imaging system
Description: Microscopic hyperspectral imaging system

Intervention type: DIAGNOSTIC_TEST
Intervention: Microscopic hyperspectral imaging system
Description: Microscopic hyperspectral imaging system

Intervention type: DIAGNOSTIC_TEST
Intervention: Microscopic hyperspectral imaging system
Description: Microscopic hyperspectral imaging system
Study: NCT05994963

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sisunatovir
Description: Administered as either capsules in fasted state or tablet in fasted or fed state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sisunatovir
Description: Administered as either capsules in fasted state or tablet in fasted or fed state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sisunatovir
Description: Administered as either capsules in fasted state or tablet in fasted or fed state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sisunatovir
Description: Administered as either capsules in fasted state or tablet in fasted or fed state.
Study: NCT00737542

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lidocaine
Study: NCT05994963

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sisunatovir
Description: Administered as either capsules in fasted state or tablet in fasted or fed state.
Study: NCT05813613

Intervention type: OTHER
Intervention: Squatting with the aid of Kynapsis Virtual Training apparatus.
Description: Squatting exercise was performed using a virtual reality (VR) machine (kynapsis) for guidance in both groups. Squats were performed while the hands were kept in front of the bodies and the knees flexed to 90 degrees following a rhythm of two seconds for descent, two second ascent mimicking the movement done on the VR machine.

Intervention type: OTHER
Intervention: Squatting with the aid of Kynapsis Virtual Training apparatus.
Description: Squatting exercise was performed using a virtual reality (VR) machine (kynapsis) for guidance in both groups. Squats were performed while the hands were kept in front of the bodies and the knees flexed to 90 degrees following a rhythm of two seconds for descent, two second ascent mimicking the movement done on the VR machine.
Study: NCT04657354

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Assessment
Description: Early surgical assessment
Study: NCT05569616

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hand massage
Description: Hand massage is a simple comfort intervention that involves touch and conveys care that can easily be incorporated independently into routine nursing care activities. Hand massage is a western technique that includes five basic classical massage manipulations, including eufluorage, petrissage, friction, tapotman and vibration. Kolcaba et al. (2006) hand massage procedure will be applied with baby oil for 20 minutes, three times a week (12 times in total) for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Play activity
Description: The number of people for the Jenga game was determined as two people in order to strengthen the social relationship among the elderly and to strengthen their psychomotor skills. Each game will be played with two people. For this reason, the elderly will be divided into five separate groups, two people each.These groups will be played the Jenga game for one hour a week on a certain day of the week, accompanied by the researcher, during the activity hours determined by the nursing home. After the game activity (Jenga) application is completed at the end of the fourth week, the post-test scales will be re-administered to the elderly by the researcher.
Study: NCT05007262

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tangningtongluo tablets
Description: Four pills each time and three times a day after meals.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcium dobesilate capsules
Description: 1 capsule at a time, tid,po.(morning, midday, and evening), used on an empty stomach.
Study: NCT06170190

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBI133
Description: IBI133:~The provisional dose levels are planned to be evaluated, but it is possible for additional and/or intermediate dose levels to be added during the course of the study. Q3W
Study: NCT05971368

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: thoracic paravertebal block
Description: o Group A: Patients will receive ultrasound guided thoraxic paravertebral block with 0.25% bupivacaine 0.4 ml/kg (max. 40 ml and not exceeding toxic dose of bupivacaine 2.5mg/kg) after induction of anesthesia.~A high-frequency linear ultrasound probe will be placed between transverse processes from the T4 level (the level of port introduction) in the paramedian plane while patients is in the lateral decubitus position. The transverse processes, superior costotransverse ligaments, and pleura will be well visualized. The block needle (22 gauge) will be advanced until it crosses the superior costotransverse ligament. The prepared 0.25% bupivacaine will be administered at 0.4 mL/kg (max. 40 mL) in the thoracic paravertebral space. Depression of the pleura will be observed as a result of the spread of local anesthetic.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: serratus anterior muscle block
Description: Group B: Patients will receive ultrasound guided serratus anterior muscle block with 0.25% bupivacaine 0.4 ml/kg (max. 40 ml and not exceeding toxic dose of bupivacaine 2.5mg/kg) after induction of anesthesia.~While the patient is in the supine position, a high-frequency linear ultrasound probe will be placed horizontally on the mid-axillary line at the level of 4th or 5th ribs on the side of the block. The serratus anterior, latissimus dorsi, and intercostal muscles will be identified. The block needle (22-gauge) will be advanced below the serratus anterior muscle (SAM) towards the fifth rib (using in-plane technique). The prepared 0.25% bupivacaine will be administered at 0.4 mL/kg (max. 40 mL) between the SAM and the rib. It will be observed that the solution of local anesthesia will spread between the SAM and the rib.
Study: NCT05117593

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FBL-MTX
Description: FBL-MTX is available as sterile liposomal dispersion for injection at nominal dose strength of 1 mg/mL of methotrexate free base. The dose of 0.1 mg was selected as starting dose in the present study. Three subsequent FBL-MTX dose levels are pre-planned: 0.33 mg, 1 mg and 2.5 mg.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will consist of sterile saline 0.9% NaCl solution.
Study: NCT05825313

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Podcast Using
Description: Students in the experimental group listened to podcast episodes any time they desired following the course every week during the semester from February 2021 to June 2021.
Study: NCT06054438

Intervention type: OTHER
Group type: OTHER
Intervention: Chinese medicine nutritional supplement Cs4
Description: Cs4 will be provided by Chinese Pharm, produced by GMP standard manufacturing. The intervention will be given according to the product instruction. Each capsule is 0.4g. According to the product sheet, adults should take 3-4 capsules daily as a way to nourish and strengthen the lungs and kidneys. In our study, the participants are people with long-COVID symptoms. Therefore, in order to achieve maximum efficacy, we will follow the directions and let participants take the maximum amount allowed by the product which is 4 capsules daily. Participants will take one capsule (each 400mg) 4 times a day, for a total of 1.6g. Treatment will last 12 weeks.

Intervention type: OTHER
Group type: OTHER
Intervention: Chinese medicine nutritional supplement Cs4
Description: Cs4 will be provided by Chinese Pharm, produced by GMP standard manufacturing. The intervention will be given according to the product instruction. Each capsule is 0.4g. According to the product sheet, adults should take 3-4 capsules daily as a way to nourish and strengthen the lungs and kidneys. In our study, the participants are people with long-COVID symptoms. Therefore, in order to achieve maximum efficacy, we will follow the directions and let participants take the maximum amount allowed by the product which is 4 capsules daily. Participants will take one capsule (each 400mg) 4 times a day, for a total of 1.6g. Treatment will last 12 weeks.
Study: NCT05210972

Intervention type: RADIATION
Intervention: Cardiac catheterization
Description: All the study population will be exposed to diagnostic coronary angiography and invasive coronary intervention as per standard guidelines.

Intervention type: RADIATION
Intervention: Cardiac catheterization
Description: All the study population will be exposed to diagnostic coronary angiography and invasive coronary intervention as per standard guidelines.

Intervention type: RADIATION
Intervention: Cardiac catheterization
Description: All the study population will be exposed to diagnostic coronary angiography and invasive coronary intervention as per standard guidelines.
Study: NCT03641430

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supportive care with OCT product
Description: Participants will apply over-the-counter product for a certain period with or without light challenge. We will perform clinical assessments of the skin associated with product application as well as assess these changes with and without light challenge. Skin biopsies will be obtained following standard medical practice and will be used to analyze skin markers related to photoaging, pigmentation, oxidative stress, and other dermatologic conditions.
Study: NCT04655638

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Flow Nasal Therapy
Description: High flow nasal therapy will be delivered by any device (standalone machine or ventilators able to deliver it). The initial flow rate will be set at 40 L/min and potentially increased up to 60 L/min, according to patient tolerance. Large-bore nasal prongs will be selected according to the size of patients' nostrils (i.e. 2/3 of the diameter of the patient's nostril). A surgical mask will be placed on top of the HFNT interface. The temperature will be set at 37°C or 34 °C according to the patient's comfort. The FiO2 will be adjusted to maintain SpO2 between 92-96%.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Oxygen Therapy
Description: Conventional Oxygen therapy will be delivered by any device or combination of devices used for delivering oxygen such as nasal cannula, Venturi Mask or Mask with or without a reservoir bag as per usual local practice. Oxygen flow will be titrated to achieve SpO2 between 92-96%.
Study: NCT05310890

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai chi training
Description: Tai chi, also called tai chi chuan, is an ancient Chinese form of exercise originally created as a fighting art. It is a kind of gentle physical exercise and stretching, which involves a series of movements performed in a slow, focused manner and accompanied by deep breathing.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Group activity
Description: A organizer will lead the subjects to participate in group activities once a quarter. In group activities, there will be popular science lectures and interactive games.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group activity
Description: A organizer will lead the subjects to participate in group activities once a quarter. In group activities, there will be popular science lectures and interactive games.
Study: NCT05535023

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR444245
Description: Given by vein (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: Given by vein (IV)
Study: NCT05444907

Intervention type: OTHER
Intervention: No Intervention / Exposure
Description: No intervention / exposure since this is an observational study

Intervention type: OTHER
Intervention: No Intervention / Exposure
Description: No intervention / exposure since this is an observational study
Study: NCT05841485

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of coronary microvascular dysfunction using intracoronary pressure-temperature wire
Description: The primary assessment method in this study is the measurement of coronary microvascular dysfunction using a pressure-temperature wire to determine coronary flow reserve (CFR) and index of microvascular resistance (IMR).

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of coronary microvascular dysfunction using intracoronary pressure-temperature wire
Description: The primary assessment method in this study is the measurement of coronary microvascular dysfunction using a pressure-temperature wire to determine coronary flow reserve (CFR) and index of microvascular resistance (IMR).
Study: NCT06338371

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pelvic Floor exercise training
Description: The level of sexual function was determined by implementing FSFI for all individuals included in the sample. The participants were divided into two groups, control and training groups, using the randomization program on the computer. Pelvic floor exercise training was given to one group. Trainings were conducted online on different days. Each training lasted 120 minutes. After training was completed, women in the training group were instructed to perform three sets of 8-12 repetitive pelvic floor muscle contractions per day and to use an exercise diary to record their practice. Women in the training group were also given a booklet and the recording of the training video was shared. the training, a brochure explaining how to perform the pelvic floor muscle exercises, which was included in the training content, was prepared and delivered to the training group on the first day of each week. After the training, FSFI was applied to both groups 3 times, in the 1st, 2nd, and 3rd months.