TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05644184

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 (mOPV1)
Description: The Sabin Monovalent Oral Poliomyelitis Vaccine Type 1 control and challenge vaccine (mOPV1) contains ≥ 10\^6.0 CCID50 per 0.1 mL (2 drops) dose.
Study: NCT06301386

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: Patients receive oral everolimus once daily on days 1-28. Treatment repeats every 28 days in the absence of disease progression or unacceptable toxicity.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1
Description: 200mg intravenously every 3 weeks (Q3W), was administered until the occurrence of unacceptable toxic effects, or disease progression, withdrawal of consent, or withdrawal as judged by the investigator.
Study: NCT04699396

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mobilisation With Movement 1
Description: Application of a sustained passive accessory movement to a joint (talus or fibula) while the patient actively performs a forward lean/lunge that was previously limited.~3 sets of 10 repetitions of a glide applied to the talus were performed, followed by 3 sets of 10 repetitions of a glide applied to the fibula.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mobilisation With Movement 1
Description: Application of a sustained passive accessory movement to a joint (talus or fibula) while the patient actively performs a forward lean/lunge that was previously limited.~3 sets of 10 repetitions of a glide applied to the talus were performed, followed by 3 sets of 10 repetitions of a glide applied to the fibula.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mobilisation With Movement 2
Description: Application of a sustained passive accessory movement to a joint (talus or fibula) while the patient actively performs a forward lean/lunge that was previously limited.~3 sets of 10 repetitions of a glide applied to the fibula were performed, followed by 3 sets of 10 repetitions of a glide applied to the talus.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mobilisation With Movement 2
Description: Application of a sustained passive accessory movement to a joint (talus or fibula) while the patient actively performs a forward lean/lunge that was previously limited.~3 sets of 10 repetitions of a glide applied to the fibula were performed, followed by 3 sets of 10 repetitions of a glide applied to the talus.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The Placebo group participants performed the same number of sets and repetitions (6 sets of 20 repetitions) of lean/lunge forward into dorsiflexion, without any glide application.
Study: NCT04697173

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single consent
Description: A single consent form for possible procedures the child may undergo while in the PICU
Study: NCT04754074

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Weekly education related to behavior change

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized coaching
Description: Weekly calls with personalized coaches in behavior modification, nutrition, and physical activity/exercise.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weekly behavior modification challenges
Description: Weekly challenges to address behavior change
Study: NCT05663593

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK31858, tablet
Description: Starting dose in single ascending dose: 5 mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo, tablet
Description: Matching placebo
Study: NCT05250804

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Helfer Skin Tap Technique
Description: Helfer Skin Tap Technique is a technique in which the researcher taps the Dorso gluteal muscle by counting 1-15 with the palmar aspect of fingers (non-dominant hand) in rhythmic manner before inserting the injection intra muscularly at 90 degree and remove the needle quickly again by tapping and counting 1-3.
Study: NCT06035380

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo group
Description: aromatherapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mint oil group
Description: aromatherapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rose oil group
Description: aromatherapy
Study: NCT06490965

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive Transcranial Magnetic Stimulation
Description: Transcranial Magnetic Stimulation (TMS) involves generating a magnetic field with specific spatial and temporal properties, allowing the induction of electric current in conductive material near this field. The electro-physiological principle of TMS is based on placing a coil over the skull that will induce a magnetic field generating action potentials in neuronal tissue in response to each TMS pulse. The repetitive application of TMS pulses (rTMS) allows for the modulation of neuronal excitability for a period after rTMS, ranging from inhibition, in the case of low frequencies (\~1 Hz), or facilitation if high frequencies (equal to or greater than 5 Hz) are used.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation
Description: Transcranial Magnetic Stimulation (TMS) involves generating a magnetic field with specific spatial and temporal properties, allowing the induction of electric current in conductive material near this field. The electro-physiological principle of TMS is based on placing a coil over the skull that will induce a magnetic field generating action potentials in neuronal tissue in response to each TMS pulse. The repetitive application of TMS pulses (rTMS) allows for the modulation of neuronal excitability for a period after rTMS, ranging from inhibition, in the case of low frequencies (\~1 Hz), or facilitation if high frequencies (equal to or greater than 5 Hz) are used.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neuronavigation
Description: Neuronavigation is a non-invasive method that allows the creation of computerized three-dimensional models of brain structures based on neuroimaging exams of each individual (e.g., cranial magnetic resonance imaging). As such, this method has been used for various purposes, such as assisting in neurosurgery or mapping functional regions of the brain, but also in the context of TMS (Transcranial Magnetic Stimulation). In this latter area, its use as support for TMS has been employed for therapeutic, diagnostic, and research purposes. The neuronavigation system consists of several components, namely a locating camera, locators for the TMS coil, an adjustable headband with locators, a calibration system for these elements, and the neuronavigation software, which is installed on a supporting computer.
Study: NCT05210764

Intervention type: DRUG
Intervention: propofol
Description: General anesthesia is induced and maintained mainly with propofol.

Intervention type: DRUG
Intervention: sevoflurane
Description: General anesthesia is induced and maintained mainly with sevoflurane.

Intervention type: DRUG
Intervention: S-ketamine
Description: General anesthesia is induced mainly with S-ketamine and maintained mainly with propofol.
Study: NCT06142526

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DividPro film
Description: DividPro Film is a sterile biodegradable translucent film that served as a physical barrier for preventing the adhesion between two adjacent layers of tissue in wound healing process.
Study: NCT04856670

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Cataract surgery- Manual or femtosecond laser assisted

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Cataract surgery- Manual or femtosecond laser assisted

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Cataract surgery- Manual or femtosecond laser assisted

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Cataract surgery- Manual or femtosecond laser assisted
Study: NCT03610542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Triggers for anxiety
Description: Students learn about different triggers for anxiety, what the signs and indicators of anxiety are, and identify their own triggers for anxiety
Study: NCT05733403

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: isotonic solution
Description: Isotonic solutions are IV fluids that have a similar concentration of dissolved particles as blood.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: isotonic solution
Description: Isotonic solutions are IV fluids that have a similar concentration of dissolved particles as blood.
Study: NCT05993871

Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical Evaluation/Questionnaires
Description: Anthropometric measures, somatosensory assessment (NPS, UENS, TCNS), autonomic assessment (COMPASS-31, Ewing battery), and severity and quality of life evaluation (NPS, TCNS, COMPASS-31, and EuroQOL-5D-5L index score)
Study: NCT05733403

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Noradrenaline
Description: Noradrenaline itself is classified as a sympathomimetic drug: its effects when given by intravenous injection of increasing heart rate and force and constricting blood vessels make it very useful for treating medical emergencies that involve critically low blood pressure.
Study: NCT06490965

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuronavigation
Description: Neuronavigation is a non-invasive method that allows the creation of computerized three-dimensional models of brain structures based on neuroimaging exams of each individual (e.g., cranial magnetic resonance imaging). As such, this method has been used for various purposes, such as assisting in neurosurgery or mapping functional regions of the brain, but also in the context of TMS (Transcranial Magnetic Stimulation). In this latter area, its use as support for TMS has been employed for therapeutic, diagnostic, and research purposes. The neuronavigation system consists of several components, namely a locating camera, locators for the TMS coil, an adjustable headband with locators, a calibration system for these elements, and the neuronavigation software, which is installed on a supporting computer.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Magnetic Resonance Imaging (MRI) is a non-invasive medical imaging technique that generates detailed images of the internal structures of the body using a strong magnetic field and radio waves. It provides high-resolution images of soft tissues, such as organs, muscles, and the brain, helping doctors diagnose and monitor various conditions, including injuries, tumors, and neurological disorders. MRI is particularly useful because it does not involve ionizing radiation, making it safer for patients than other imaging methods like X-rays or CT scans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Magnetic Resonance Imaging (MRI) is a non-invasive medical imaging technique that generates detailed images of the internal structures of the body using a strong magnetic field and radio waves. It provides high-resolution images of soft tissues, such as organs, muscles, and the brain, helping doctors diagnose and monitor various conditions, including injuries, tumors, and neurological disorders. MRI is particularly useful because it does not involve ionizing radiation, making it safer for patients than other imaging methods like X-rays or CT scans.
Study: NCT06070038

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integrated Behaviour Change Based Intervention Materials
Description: The intervention will be delivered over a three-month period as a series of four zoom hosted workshops, online content, and a moderated social support group. Zoom workshops will last 45 minutes and will target key constructs from the integrated behavior change model. Main topics of the workshops are autonomy Supportive parenting (Week 1), goal setting and outcome beliefs (Week 3), physical activity norms (Week 5), and encouraging self-efficacy and maintenance (Week 8). Following each workshop, participants will receive links to online content that builds on workshop themes, such as messages, worksheets, and reflection tasks. Throughout the trial, participants will be able to participate in social support chat groups to discuss their progress with other members of the intervention group and intervention facilitators.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Integrated Behaviour Change Based Intervention Materials
Description: The intervention will be delivered over a three-month period as a series of four zoom hosted workshops, online content, and a moderated social support group. Zoom workshops will last 45 minutes and will target key constructs from the integrated behavior change model. Main topics of the workshops are autonomy Supportive parenting (Week 1), goal setting and outcome beliefs (Week 3), physical activity norms (Week 5), and encouraging self-efficacy and maintenance (Week 8). Following each workshop, participants will receive links to online content that builds on workshop themes, such as messages, worksheets, and reflection tasks. Throughout the trial, participants will be able to participate in social support chat groups to discuss their progress with other members of the intervention group and intervention facilitators.
Study: NCT03610542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Triggers for anxiety
Description: Students learn about different triggers for anxiety, what the signs and indicators of anxiety are, and identify their own triggers for anxiety

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Identifying and challenging negative thoughts
Description: Students learn about the types of unrealistic thoughts that underpin anxiety and how anxiety can be reduced with more realistic thoughts. Students identify their own unrealistic thoughts that contribute to anxiety and what more realistic thoughts can be used.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Identifying and challenging negative thoughts
Description: Students learn about the types of unrealistic thoughts that underpin anxiety and how anxiety can be reduced with more realistic thoughts. Students identify their own unrealistic thoughts that contribute to anxiety and what more realistic thoughts can be used.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Relaxation
Description: Students are taught to relax through (1) breathing exercises, (2) progressive muscle relaxation, and (3) imagery. Student practice these techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Relaxation
Description: Students are taught to relax through (1) breathing exercises, (2) progressive muscle relaxation, and (3) imagery. Student practice these techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal Setting
Description: Students learn how to set goals, monitor goal progress, and check when goals have been achieved. Students then identify their own goals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal Setting
Description: Students learn how to set goals, monitor goal progress, and check when goals have been achieved. Students then identify their own goals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Overcoming avoidance
Description: Students identify ways that they avoid anxiety-provoking situations (e.g., procrastinating exam study). Students develop plans for exposure to anxiety-provoking situations and learn study strategies to build confidence.
Study: NCT03610542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Overcoming avoidance
Description: Students identify ways that they avoid anxiety-provoking situations (e.g., procrastinating exam study). Students develop plans for exposure to anxiety-provoking situations and learn study strategies to build confidence.
Study: NCT04193150

Intervention type: DIAGNOSTIC_TEST
Intervention: Full pulmonary specialist assessment
Description: Please see description for the intervention arm.
Study: NCT06059755

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross education
Description: For strength training resistance exercises with a load of 60% of one repetition maximum will be performed targeting the muscle involved in upper limb function. Strength will be measured using the grip strength test/hand held dynamometer. Patients will undergo 45 minute session per day, 3 days per week for 6 weeks.
Study: NCT04980183

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Arthroscopic surgical robot
Description: The surgeon performs cruciate ligament bone canal positioning and ligament reconstruction with the assistance of an arthroscopic surgical robot

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional arthroscopic cruciate ligament reconstruction
Description: The surgeon performs conventional arthroscopic cruciate ligament reconstruction surgery without other auxiliary equipment
Study: NCT05386433

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paxlovid
Description: Paxlovid contains two medicines: nirmatrelvir and ritonavir. Nirmatrelvir \[PF-07321332\] is a SARS-CoV-2 main protease (Mpro) inhibitor (also known as SARS-CoV2 3CL protease inhibitor) that works by inhibiting viral replication in the early stages of the disease to prevent progression to severe COVID-19.~Ritonavir is co-administered with nirmatrelvir to help slow its metabolism in order for it to remain active in the body for longer periods of time at higher concentrations to help combat the virus.
Study: NCT05983783

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: This is Triple drug regimen for mHSPC

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rezvilutamide
Description: This is doubling drug regimen for mHSPC
Study: NCT05983146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-7053 Injection
Description: HRS-7053 is administered by intravenous (IV) infusion once a week (QW) for one treatment cycle every 4 weeks
Study: NCT06059755

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror Therapy
Description: Participants will be asked to sit in front of a table of appropriate height with their arms resting on the table and a mirror (35 cm × 35 cm) placed between the patient's arms. The non-affected arm will be placed in front of the mirror and the affected arm will be placed and obscured. Appropriate movement tasks will be selected according to the function of the affected upper limb. This exercise will be performed 45 minutes per day, 3 times per week for 6 weeks
Study: NCT05786118

Intervention type: OTHER
Intervention: No intervention
Description: There is no intervention in this study

Intervention type: OTHER
Intervention: No intervention
Description: There is no intervention in this study
Study: NCT06274762

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Training and BSE application on a model
Description: A breast cancer awareness training designed according to the headings of sensitivity, seriousness, benefit, obstacle perception, health motivation and self-efficacy, which are the steps of the health belief model, followed by applied BSE on a model.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training and BSE application on a model
Description: A breast cancer awareness training designed according to the headings of sensitivity, seriousness, benefit, obstacle perception, health motivation and self-efficacy, which are the steps of the health belief model, followed by applied BSE on a model.
Study: NCT06353139

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Modified olfactory training device
Description: Conduct olfactory training in patients with olfactory disorders

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Modified olfactory training device
Description: Conduct olfactory training in patients with olfactory disorders
Study: NCT05993871

Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical Evaluation/Questionnaires
Description: Anthropometric measures, somatosensory assessment (NPS, UENS, TCNS), autonomic assessment (COMPASS-31, Ewing battery), and severity and quality of life evaluation (NPS, TCNS, COMPASS-31, and EuroQOL-5D-5L index score)

Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical Evaluation/Questionnaires
Description: Anthropometric measures, somatosensory assessment (NPS, UENS, TCNS), autonomic assessment (COMPASS-31, Ewing battery), and severity and quality of life evaluation (NPS, TCNS, COMPASS-31, and EuroQOL-5D-5L index score)
Study: NCT05386433

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: standard-of-care
Description: standard-of-care of COVID-19

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standard-of-care
Description: standard-of-care of COVID-19
Study: NCT04526977

Intervention type: DIAGNOSTIC_TEST
Intervention: Immune response study
Description: * ACE2 and CD26 receptor study~* Cytokine profile: Quantification of plasma cytokine levels~* SARS-CoV-2 CD4/CD8 T cell response~* TLR7/8 activation~* KIR characterization
Study: NCT05337241

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Saline Enhanced Radiofrequency (SERF) Ablation
Description: The Durablate intramural needle catheter delivers heated saline to target tissue in the left ventricle to target mid-myocardial and epicardial VT substrates