TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04246346

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: An interactive chatbot for patient decision aid
Description: A chatbot embedded into a mobile application which is able to bidirectionally interact with patients and provide standard general information, quantitative risk information on the possible outcomes of cataract surgery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Senior ophthalmologists
Description: Senior ophthalmologists would communicate with patients and provide standard general information, quantitative risk information on the possible outcomes of cataract surgery.
Study: NCT05407324

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dazucorilant 300 mg
Description: 300 mg of dazucorilant will be administered once daily in 4 softgel capsules of 75 mg dazucorilant/capsule.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dazucorilant 150 mg
Description: Dazucorilant and placebo will be administered once daily in 4 softgel capsules, 2 capsules with 75 mg dazucorilant/capsule and 2 capsules of placebo equivalent.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered once daily in 4 softgel capsules of placebo equivalent.
Study: NCT06584890

Intervention type: OTHER
Intervention: decision
Description: decision-making process regarding patient discharge from the Intensive Care Unit (ICU)

Intervention type: OTHER
Intervention: decision
Description: decision-making process regarding patient discharge from the Intensive Care Unit (ICU)
Study: NCT05626439

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Staccato alprazolam
Description: Study participants will receive single dose of Staccato alprazolam by inhalation at pre-specified time points.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Staccato alprazolam
Description: Study participants will receive single dose of Staccato alprazolam by inhalation at pre-specified time points.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral alprazolam
Description: Study participants will receive single dose of oral alprazolam at pre-specified time points.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral alprazolam
Description: Study participants will receive single dose of oral alprazolam at pre-specified time points.
Study: NCT05321511

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triptorelin acetate (a-GnRH)
Description: Adminsitration of triptoreline acetate 0.2 mg for final oocyte maturation in the second ovarian stimuation inthe Double stimulation protocol.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ovitrelle® (hCG)
Description: Adminsitration of coriogonadotropine alfa 250 mcg for final oocyte maturation in the second ovarian stimuation inthe Double stimulation protocol.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decapeptyl 0.1 mg® (a-GnRH) and Ovitrelle® (hCG) used together
Description: Adminsitration of triptoreline acetate 0.2 mg and coriogonadotropine alfa 250 mcg for final oocyte maturation in the second ovarian stimuation inthe Double stimulation protocol.
Study: NCT04918498

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: early physiotherapy programs
Description: establishment of multidisciplinary teams, safety assessment, early activity physiotherapy and respiratory physiotherapy

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: routine treatment
Description: provide routine nursing and rehabilitation program
Study: NCT05749250

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acoustic cavitation of ultrasound enhancing agents
Description: Cavitation therapy
Study: NCT05173675

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empathy in Action for life with diabetes.
Description: In Phase 1 (Months 1-6) participants receive (Program):~1. Empathetic communications: A dedicated partner (lightly-trained lay person) who communicates with them via phone with timing and frequency defined by the participant within certain parameters. Two letters mailed during the 6 months that compile anonymized learnings from all participants in the callers panel of 10-20 participants, written as a newsletter to share back with the participant.~2. Material Incentives: One choice of health tool (weight scale or pedometer) selected with the caller in week 1 and expected to be received in weeks 3-5. Two small recognition gifts (valued at US$25) chosen by the caller based on their understanding of the participants preferences, and sent at month 2.5 and 4.5.~3. Educational Materials: Printed DM management educational materials mailed right after enrollment and randomization, and expected to be received in weeks 1-2.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control Phase 2 Materials Only
Description: 1. Material Incentives:~   a. Choice of health tool (weight scale or pedometer) and 2 health promoting gifts chosen by the caller at the end of their 6 month measurement visit.~   i. Health tool is mailed out within the 7th month ii. Health promoting gifts are mailed out in the 8th and 10th month~2. Educational Materials a. The same educational materials mailed to participants in the intervention arm Program will be mailed to control arm participants after they complete their 6 months visit
Study: NCT05420870

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: exercise
Description: Six weeks of exercise intervention~To meet weekly 150 min of moderate to vigorous physical activity and twice weekly strength exercise General description of the exercise program~Main goal of the supervised exercise (1 hour per session, twice a week) are three folds. 1) Instruct participants to correctly perform prescribed exercises. 2) Encourage participants to be compliant to exercise program. 3) Participants were encouraged to hand in their exercise diary~Main goal of the home-based exercise is to perform calisthenics exercise daily. Participants were encouraged to perform at least one set of exercise (8-12 different exercises) and stretching (At least 3 days per week, but preferably most of the days) daily~Basic 8 exercises which increase ROM and strength of shoulder, lower back, Hip, Knee and ankle Additional 4 exercise to increase core strength and stability
Study: NCT05941455

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Venus-Neo Surgical Aortic Valve
Description: Implant of a Venus-Neo Surgical Aortic Valve
Study: NCT04468516

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KKT
Description: Vibroacoustic sound waves applied focally.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: sham KKT
Description: sham KKT
Study: NCT05553301

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Quadrivalent Influenza mRNA Vaccine MRT5407
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Quadrivalent Influenza mRNA Vaccine MRT5407
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Recombinant Influenza Vaccine
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza Standard Dose Vaccine
Description: Pharmaceutical Form: Liquid suspension for injection in pre-filled syringe~Route of Administration: Intramuscular Injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza High-Dose Vaccine
Description: Pharmaceutical Form: Liquid suspension for injection in pre-filled syringe~Route of Administration: Intramuscular Injection
Study: NCT05661851

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Investigational Lubricating Eye Drop in a Novelia® bottle
Description: Investigational Product

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Blink® Tears eye Drops
Description: Control Product
Study: NCT06103188

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo pill will be given to the patients 1 hour prior to their planned surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Diazepam
Description: Diazepam will be given to the patients 1 hour prior to their planned surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin
Description: Melatonin will be given to the patients 1 hour prior to their planned surgery.
Study: NCT06343805

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor
Study: NCT06040866

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise training
Description: Exercise training will be applied in the non-menstrual period during 2 menstrual cycles as stretching and relaxation exercises. Stretching exercises will include general stretching and specific stretching exercises and will take approximately 20 minutes in total. After the stretching exercises, relaxation exercise will be performed with diaphragmatic breathing for 10 minutes. The exercises will be performed with music accompanied by a physiotherapist once a week, and it will be recommended to do the exercises as a home program for 2 sessions a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Exercise training will be applied in the non-menstrual period during 2 menstrual cycles as stretching and relaxation exercises. Stretching exercises will include general stretching and specific stretching exercises and will take approximately 20 minutes in total. After the stretching exercises, relaxation exercise will be performed with diaphragmatic breathing for 10 minutes. The exercises will be performed with music accompanied by a physiotherapist once a week, and it will be recommended to do the exercises as a home program for 2 sessions a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain neuroscience education
Description: Participants in the first research arm will be given pain neuroscience education once a week for 2 weeks after their first menstruation. The training will be repeated with a reminder session at the end of the 2nd menstruation.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Biomedical pain education
Description: Participants in the second research arm will be given biomedical pain education once a week for 2 weeks after their first menstruation. The training will be repeated with a reminder session at the end of the 2nd menstruation.
Study: NCT05869903

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orforglipron
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orforglipron
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orforglipron
Description: Administered orally.
Study: NCT06407986

Intervention type: DIAGNOSTIC_TEST
Intervention: pulmonary function test
Description: Whether the estimated value of FEV1 and FVC is greater than 80%.

Intervention type: DIAGNOSTIC_TEST
Intervention: pulmonary function test
Description: Whether the estimated value of FEV1 and FVC is greater than 80%.
Study: NCT04917289

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Started chemotherapy or change the current adjuvant therapy
Study: NCT05869903

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally.
Study: NCT05083130

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: a wake prone positioning
Description: The team will give written and verbal advice and if necessary aid patients' positioning themselves in the prone position for at least 8 hours per day. The exact duration of prone sessions will be determined according to ward schedules to take account of nursing procedures, meal times and mitigation strategies. Other methods to encourage the maintenance of prone position includes phone calls to patients, carers or education of carers.
Study: NCT05962580

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Isolated anterior cruciate ligament reconstruction with lateral extra articular tenodesis
Description: Anatomical single bundle ACLR with modified Lemiere technique

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Isolated anterior cruciate ligament reconstruction only
Description: arthroscopic anatomical single bundle ACL Reconstruction
Study: NCT06000943

Intervention type: OTHER
Intervention: Low vs Intermediate vs High surgical risk stratified according with SAPT/DAPT/OAC and OAC+SAPT
Description: All patients undergoing TAVR will be stratified according with surgical risk level and all combination of antithrombotic therapy at discharge~Low risk (SAPT vs DAPT and OAC vs OAC+SAPT) Intermediate risk (SAPT vs DAPT and OAC vs OAC+SAPT) High risk (SAPT vs DAPT and OAC vs OAC+SAPT)

Intervention type: OTHER
Intervention: Low vs Intermediate vs High surgical risk stratified according with SAPT/DAPT/OAC and OAC+SAPT
Description: All patients undergoing TAVR will be stratified according with surgical risk level and all combination of antithrombotic therapy at discharge~Low risk (SAPT vs DAPT and OAC vs OAC+SAPT) Intermediate risk (SAPT vs DAPT and OAC vs OAC+SAPT) High risk (SAPT vs DAPT and OAC vs OAC+SAPT)

Intervention type: OTHER
Intervention: Low vs Intermediate vs High surgical risk stratified according with SAPT/DAPT/OAC and OAC+SAPT
Description: All patients undergoing TAVR will be stratified according with surgical risk level and all combination of antithrombotic therapy at discharge~Low risk (SAPT vs DAPT and OAC vs OAC+SAPT) Intermediate risk (SAPT vs DAPT and OAC vs OAC+SAPT) High risk (SAPT vs DAPT and OAC vs OAC+SAPT)
Study: NCT06345989

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Alginate impression
Description: Alginate impression

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intraoral scan
Description: Intraoral scan with Trios 3Shape Scanner
Study: NCT05231785

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALN-APP
Description: ALN-APP will be administered intrathecally (IT)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALN-APP
Description: ALN-APP will be administered intrathecally (IT)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered IT
Study: NCT06354829

Intervention type: DIAGNOSTIC_TEST
Intervention: Medical imaging procedures
Description: The following medical imaging procedure will b applied: Magnetic resonance images (MRI), computerized tomography images (CT), and ultrasound images (US).

Intervention type: DIAGNOSTIC_TEST
Intervention: Medical imaging procedures
Description: The following medical imaging procedure will b applied: Magnetic resonance images (MRI), computerized tomography images (CT), and ultrasound images (US).
Study: NCT05006768

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Barcimiant
Description: 1 tablet contains 4 mg Barcitinib

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olumiant (first dose)
Description: 1 tablet contains 4 mg Barcitinib

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olumiant (second dose)
Description: 1 tablet contains 4 mg Barcitinib
Study: NCT05509816

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imlunestrant
Description: Administered orally.
Study: NCT05913089

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2450 injection + Chemotherapy
Description: TQB2450 injection is a humanized monoclonal antibody targeting programmed death ligand -1 (PD-L1).~Chemotherapy is a systematic treatment that kill fast growing cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2450 injection + Anlotinib Hydrochloride Capsule
Description: TQB2450 injection is a humanized monoclonal antibody targeting programmed death ligand -1 (PD-L1).~Anlotinib hydrochloride is a muti-target tyrosine kinase inhibitor.
Study: NCT06557070

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Emotional Freedom Technique
Description: Emotional freedom technique (EFT) is a method to help manage emotions and troubling thoughts and lower stress and anxiety. EFT is applying by tapping. To do EFT, you tap your fingertips on certain points on your hand, head, and torso which are used in acupuncture.
Study: NCT06004999

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole body vibration
Description: All patients will be pedaling for 5 minutes, followed by a warm-up phase with 5 minutes of stretching for the hamstring, gastrocnemius, soleus, and quadriceps muscles.~Afterward, the following exercise program on the vibration platform will be applied to the 1st group.~* Lunge,~* Squat,~* Deep squat,~* Wide stance squat,~* Calves,~* Deep calves. The exercise time will be 6 minutes in the first week, and the exercise time will be increased in the following weeks, and the total exercise time will continue at 18 minutes in the last week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The exercise program on flat ground without a vibration platform
Description: All patients will be pedaling for 5 minutes, followed by a warm-up phase with 5 minutes of stretching for the hamstring, gastrocnemius, soleus, and quadriceps muscles.~Afterward, the following exercise program will be applied to the group.~The exercise program will be applied to the 2nd group (controls) on flat ground without a vibration platform.~* Lunge,~* Squat,~* Deep squat,~* Wide stance squat,~* Calves,~* Deep calves. The exercise time will be 6 minutes in the first week, and the exercise time will be increased in the following weeks, and the total exercise time will continue at 18 minutes in the last week.
Study: NCT05448183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab, Gemcitabine,Oxaliplatin
Description: Toripalimab, 240mg, IV infusion, every 3 weeks (q3w), combined withTACE (Gemcitabine 1000mg/m2 , Oxaliplatin 135mg/m2) in a cycle of 3 weeks(q3w).
Study: NCT05475132

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exergaming
Description: exercise games will be done for a total of 8 weeks ,100min of exergaming/week (5 days × 20 min).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Dexterity Exercises
Description: Exercises traditionally used for dexterity will be done for 8 weeks, 100min of exercises/week (5days × 20 min)
Study: NCT04800354

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-led Mindfulness Based Intervention
Description: Nurses will read patients a brief (1 minute) scripted, introduction to mindfulness and then have them listen to a very brief (1 minute 30 second) guided mindfulness practice validated in our prior research to encourage focused attention on breath and body sensations and open monitoring and acceptance of discursive thoughts, negative emotions, and pain. Finally, patients will be given an audio recording of the mindful pain management technique for use any time they experience intense pain or take pain medication before and after surgery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-led Pain Psychoeducation
Description: Nurses will provide psychoeducation about pain along with common pain coping strategies, such as rest, ice, and elevation, for use any time they experience intense pain or take pain medication before and after surgery.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Nurse-led Pain Psychoeducation
Description: Nurses will provide psychoeducation about pain along with common pain coping strategies, such as rest, ice, and elevation, for use any time they experience intense pain or take pain medication before and after surgery.
Study: NCT05754931

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep neck flexors training + Conventional therapy
Description: Hold for 10 sec and repeated 10 times.Patients will be treated 3 times a week for 4 consecutive weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscles energy techniques + conventional therapy
Description: position of patient is in maximal comfort and lengthening After engaging the barrier use of an isometric contraction Feel the release and lengthen the muscle repeated for 4 time per session Patients will be treated 3 times a week for 4 consecutive weeks
Study: NCT05317182

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Occlusal Splints Analogic-Analogic
Description: Take a conventional impression to the patient and conventional fabrication of the splint.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Occlusal Splints Analogic-Digital
Description: Take a conventional impression to the patient and digital fabrication of the splint.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Occlusal Splints Digital-Digital
Description: Take a digital impression to the patient and digital fabrication of the splint.
Study: NCT06295289

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hybrid Closed-loop Insulin Delivery System
Description: The Hybrid Closed-loop Insulin Delivery System system consisted of a Medtronic pump, a continuous glucose monitoring system（SIBIONICS®）and an open-source algorithm integrated into the phone. Insulin pump therapy group consisted of a Medtronic pump, and a continuous glucose monitoring system（SIBIONICS®). The difference between the two groups is that the artificial pancreas system automatically regulates the basal rate to maintain blood glucose in a target range.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Insulin pump
Description: Participants used conventional insulin pumps to control blood glucose, At the same time, a continuous glucose monitoring system was used to monitor glucose changes. Health care providers adjust the insulin dose of patients according to their blood glucose level.