TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06736041

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: M-M-R II vaccine
Description: Pharmaceutical form:Powder, lyophilized, for suspension for reconstitution-Route of administration:Subcutaneous or Intramuscular

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: M-M-R II vaccine
Description: Pharmaceutical form:Powder, lyophilized, for suspension for reconstitution-Route of administration:Subcutaneous or Intramuscular

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RotaTeq
Description: Pharmaceutical form:Solution-Route of administration:Oral

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: RotaTeq
Description: Pharmaceutical form:Solution-Route of administration:Oral

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaxelis vaccine
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaxelis vaccine
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Varivax
Description: Pharmaceutical form:Powder, lyophilized, for suspension for reconstitution-Route of administration:Subcutaneous or Intramuscular

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Varivax
Description: Pharmaceutical form:Powder, lyophilized, for suspension for reconstitution-Route of administration:Subcutaneous or Intramuscular

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Hexaxim Vaccine
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hexaxim Vaccine
Description: Pharmaceutical form:Suspension for injection-Route of administration:Intramuscular
Study: NCT06737393

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Backfill
Description: Participants undergoing laparoscopic hysterectomy have the bladder filled with 200 mL saline prior to Foley removal at the end of surgery.
Study: NCT06738550

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: inulin
Description: In the patients of the experimental group, the nutritional intervention is personalized, agave inulin supplementation is provided 9 gr per day, A 6-month follow-up is provided

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lactulose oral solution
Description: In the patients of the experimental group, the nutritional intervention is personalized, A 6-month follow-up is provided and taken syrup lactulose 10 ml every 8 hours
Study: NCT06756490

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HY-2003 (10 mg/ml), BELKYRA and placebo
Description: Participants received HY-2003 (10 mg/ml), or BELKYRA, or placebo administered up to 10 mL per treatment session at intervals of approximately 4 weeks for up to a maximum of 6 treatments.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HY-2003 (5 mg/ml) and placebo
Description: Participants received HY-2003 (5 mg/ml) or placebo administered up to 10 mL per treatment session at intervals of approximately 2 weeks for up to a maximum of 6 treatments.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HY-2003 (5 mg/ml) and placebo
Description: Participants received HY-2003 (10 mg/ml) or placebo administered up to 10 mL per treatment session at intervals of approximately 4 weeks for up to a maximum of 6 treatments. It is possible to explore the maximum number of administrations exceeding six treatment sessions.
Study: NCT06758271

Intervention type: DRUG
Intervention: Avacopan
Description: oral administration
Study: NCT06770478

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 68Ga-MY6349 PET/CT Scan
Description: The imaging agent 68Ga-MY6349 used in this project is synthesized following the standards for radiopharmaceutical production, with reference to the Chinese Pharmacopoeia (quality standards for 18F-FDG). The pH value is between 5.0 and 8.0; the radiochemical purity is not less than 95%, and the bacterial endotoxin content in each milliliter of solution is less than 15EU; the radioactive concentration is not less than 37 MBq/mL; the solvent residues comply with the regulations. Specification: 185\~1850 MBq/ml Characteristics: Clear, colorless, no visible particles. Radioactive physical half-life: 68Ga is 68 minutes. Expiry: Calculated from the time of labeling, stable for 3 half-lives. Administration method: Intravenous injection. Dosage: 0.05-0.1mCi/kg, flush with 5 mL of saline after injection.
Study: NCT06774521

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: There is no intervention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: reformer
Description: Reformer exercises:~Foodwork Swan Short Spin Long Stretch Keen Stretch Hug Tree Bridge Pulling Straps Short Box Abdominal Hundred Twist Star

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mat
Description: Mat exercises:~Neck exercises Trunk stabilization exercises Shoulder exercises Posture exercises
Study: NCT06772155

Intervention type: PROCEDURE
Intervention: Ventriculostomy
Description: Involves inserting a catheter into the brain's ventricular system to drain cerebrospinal fluid (CSF) and reduce intracranial pressure (ICP). This is a common procedure performed in this type of patient. It can be performed by a frontal approach, using a standard point 10cm from the nasion and 3cm lateral to the midline in the skull. A burr hole is performed and then the catheter is inserted in the frontal horn of the ventricular system. Then the catheter is tunneled subcutaneously and connected to an external ventricular drain collection system that allows also ICP measurement.

Intervention type: PROCEDURE
Intervention: Ventriculostomy + Locking Device
Description: Involves inserting a catheter into the brain's ventricular system to drain cerebrospinal fluid (CSF) and reduce intracranial pressure (ICP). This is an alternative procedure performed for this type of patient. It can be performed by a frontal approach, using a standard point 10cm from the nasion and 3cm lateral to the midline in the skull. A burr hole is performed and then the catheter is inserted in the frontal horn of the ventricular system. During the insertion, a locking device is attached and secured at the burr hole defect. Then the catheter is tunneled subcutaneously and connected to an external ventricular drain collection system that allows also ICP measurement.
Study: NCT06771856

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care CBTi
Description: Standard Care CBTi will take 10 weeks, during which the participant will receive 5 online les-sons and 3 online face-to-face talks with the therapist. The construction of the online intervention was based on self-help materials, research of the literature, and patient interviews. It consists of 5 online les-sons and incorporates elements commonly used in face-to-face CBTi. The 5 online lessons, one introduced every second week, cover the following topics: Education, stimulus control, sleep restriction, relaxation, cognitions. The intervention is supported by online coaching, with feedback aimed at reviewing exercis-es, clarifying information, and motivating patients to continue the course and make necessary behavioral changes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Care CBTi
Description: Standard Care CBTi will take 10 weeks, during which the participant will receive 5 online les-sons and 3 online face-to-face talks with the therapist. The construction of the online intervention was based on self-help materials, research of the literature, and patient interviews. It consists of 5 online les-sons and incorporates elements commonly used in face-to-face CBTi. The 5 online lessons, one introduced every second week, cover the following topics: Education, stimulus control, sleep restriction, relaxation, cognitions. The intervention is supported by online coaching, with feedback aimed at reviewing exercis-es, clarifying information, and motivating patients to continue the course and make necessary behavioral changes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stepped Care CBTi
Description: The stepped care approach in CBTi entails a two-step approach. Participants in this group all receive an initial entry level session of 1 hour delivered by a trained physiotherapist. Step 1: The entry level in this stepped care approach will imply a single, 1-hour long session, administered by a physiotherapist. This single session will cover: 1) education on sleep, sleep pressure, circadian rhythms; 2) introducing entry-level CBT-i principles (e.g., optimizing sleep environment, pre-bedtime food and beverage consumption) 3) pinpointing 2 to 3 of the most relevant strategies for the participant; and 4) creating an action plan for consistent implementation of these strategies over the next month. One month after 'Step 1' the participants' score on the Insomnia Severity Index (T1) will guide further decision making. Those with ISI scores \<12 will enter the follow-up phase immediately. Those with ISI scores ≥12 after step 1 will be referred to standard care CBTi.
Study: NCT06779578

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bipolar pulsed radiofrequency
Description: Bipolar pulsed radiofrequency ablation: the active comparator
Study: NCT04729426

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peanut Ball Position
Description: The group of healthy pregnant women who meet the inclusion criteria will be determined by randomization according to the order of application to the delivery room. A group (intervention group) will be given positions using the peanut ball tool in active phase and transition phase and the positions will be changed every 30 minutes.
Study: NCT06779578

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Mopolar pulsed radiofrequency
Description: Monopolar pulsed radiofrequency ablation: the placebo
Study: NCT06777550

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SimucaseTM
Description: experiment group - who will receive the clinical learning method using SimucaseTM
Study: NCT04593498

Intervention type: DIAGNOSTIC_TEST
Intervention: Holter recording
Description: Holter recording with Zenicor Flex ECG during 14 days.

Intervention type: DIAGNOSTIC_TEST
Intervention: Holter recording
Description: Holter recording with Zenicor Flex ECG during 14 days.

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography (Echo)
Description: Echocardiography: Comprehensive transthoracic echocardiography with special focus on atrial dimension and function.

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography (Echo)
Description: Echocardiography: Comprehensive transthoracic echocardiography with special focus on atrial dimension and function.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample
Description: Blood sample: 2 x 10 ml EDTA plasma sampled from venous blood at index and at 21 months. Troponin T, NTproBNP, Na, K, Creatinine. Sample for Biobank for future analysis.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample
Description: Blood sample: 2 x 10 ml EDTA plasma sampled from venous blood at index and at 21 months. Troponin T, NTproBNP, Na, K, Creatinine. Sample for Biobank for future analysis.

Intervention type: DIAGNOSTIC_TEST
Intervention: 24 hour ambulatory blood pressure monitoring And Arteriograph
Description: To assess artery stiffness.

Intervention type: DIAGNOSTIC_TEST
Intervention: 24 hour ambulatory blood pressure monitoring And Arteriograph
Description: To assess artery stiffness.
Study: NCT05323552

Intervention type: PROCEDURE
Intervention: Laparoscopic TEP hernia repair without curare and without orotracheal intubation.
Description: All the techniques and protocols used for this monocentric study are standardized:~* The anesthesia is general, the anesthetic products administered are identical,~* ventilation is ensured by the use of a laryngeal mask airway, without curare administered~* the surgery is an extraperitoneal laparoscopy with an optical trocar under the umbilical and two operators with the placement of a preformed type 3G polypropylene prosthesis~* the analgesic protocol is free of opioids (Opioid Free Anesthesia - OFA)
Study: NCT06658899

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CRD-4730
Description: Oral CRD-4730 in tablet form
Study: NCT06777550

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Clinical Learning
Description: Problem-based learning case-study case studies
Study: NCT06778551

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Description: A therapeutic exercise protocol will be carried out, consisting of 2 sessions per week for 8 weeks, supervised and guided by a physiotherapist. The objective is to improve thoracic mobility, as well as the strength and motor control of the scapular retractor and protractor muscles (middle and lower trapezius, rhomboids, and serratus anterior) and the rotator cuff.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control (Standard treatment)
Description: The protocol will include the application of therapeutic ultrasound. For this application, ultrasound gel will be used to reduce friction and improve the transmission of waves. Using a 5 cm² transducer, pulsed ultrasound will be applied at a frequency of 3 MHz and an intensity of 1 W/cm² for 10 minutes. Patients will be informed that they should not feel any sensation during the procedure, and if they do, the intensity will be reduced. Finally, kinesitherapy will be applied through classic shoulder mobility exercises.
Study: NCT06780839

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ensartinib
Description: Patients will receive Ensartinib 225mg QD by MRD test guided, if MRD test shows negative, only ensartinib will be given. if MRD test turns from negative to posive, patients will receive step-up treatment, which is ensartibe plus platinum - based doublet chemotherapy no more than 4 cycles. If MRD test turns from posive to negative, only ensartinib will be given. if MRD test constantly shows positive, MDT will determine the next step ensartib-based therapy.
Study: NCT06773013

Intervention type: DEVICE
Group type: OTHER
Intervention: Acoustic Resonance (Sound) Therapy
Description: Sonu consists of an acoustic Vibrational Headband worn circumferentially at the level of the forehead; and a Smartphone App, paired to the Headband. The App determines acoustic resonant frequencies of the subject's nasal cavity (using the facial image) and delivers treatment through bone conduction transducers in the headband

Intervention type: DEVICE
Group type: OTHER
Intervention: Acoustic Resonance (Sound) Therapy
Description: Sonu consists of an acoustic Vibrational Headband worn circumferentially at the level of the forehead; and a Smartphone App, paired to the Headband. The App determines acoustic resonant frequencies of the subject's nasal cavity (using the facial image) and delivers treatment through bone conduction transducers in the headband
Study: NCT06781190

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Green motherhood education
Description: Pregnant women selected for the experimental group will receive 4 weeks of green motherhood training.
Study: NCT06781684

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ulna shaft fracture fixation in children by intramedullary k wire
Description: * In the 1st group The Antegrade intramedullary k wire with appropriate diameter according to the child ulna diameter is introduced from the olecranon of the fractured ulna,cross the fracture site after good reduction under C arm in the anterioposterior and lateral views and the wire continues until reaching before the distal ulna .~* In the 2nd group The Retrograde intramedullary k wire with appropriate diameter is introduced from the diatal end of the ulna and cross the fracture site after good reduction under C arm and continues until reaching before the olecranon.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ulna shaft fracture fixation in children by intramedullary k wire
Description: * In the 1st group The Antegrade intramedullary k wire with appropriate diameter according to the child ulna diameter is introduced from the olecranon of the fractured ulna,cross the fracture site after good reduction under C arm in the anterioposterior and lateral views and the wire continues until reaching before the distal ulna .~* In the 2nd group The Retrograde intramedullary k wire with appropriate diameter is introduced from the diatal end of the ulna and cross the fracture site after good reduction under C arm and continues until reaching before the olecranon.
Study: NCT06781138

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional stabilization splint
Description: conventional versus 3D designed and printed stabilization splints

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D designed and printed stabilization splints
Description: Conventional versus 3D designed and printed stabilization splints
Study: NCT06771687

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High intensity interval training
Description: A 12-week high intensity interval training program, with 30 minutes of exercise three times a week. The trainings can be completed at home and will be digitally supervised.
Study: NCT06774911

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: YUIT
Description: Product with protein source from pea and rice.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: P_PS
Description: Product with protein source from soy protein.
Study: NCT06780878

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive muscle relaxation technique
Description: PMR focuses on the relationship between muscle tension and relaxation. By deliberately tensing a muscle group for a few seconds and then releasing the tension, individuals become more aware of the sensation of relaxation.~Group A Participants will receive PMR for 10 minutes each session, 3 sessions per week for 2 weeks and outcome measures will be recorded pre and post for each session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stretching exercises
Description: Stretching exercises are physical activities designed to improve the flexibility of muscles and joints. These exercises involve elongating specific muscle groups to enhance their elasticity and improve the range of motion around a joint.~Participants will be given 15 second stretches for each large muscle group, 3 sessions per week, for 2 weeks. Outcome measures will be assessed pre and post intervention.
Study: NCT06781307

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: skin to skin
Description: Intervention measures include 1 hour of skin-to-skin contact between mother and baby every day from day 1 to day 30 postpartum.
Study: NCT06782347

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Proactive Care
Description: The proactive care intervention was designed to be similar to proactive care approaches used successfully in the tobacco control area. These proactive care procedures have not yet been adequately evaluated in the exercise promotion area.
Study: NCT06782087

Intervention type: DRUG
Group type: OTHER
Intervention: nano chitosan
Description: nano chitosan
Study: NCT06781047

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Trunk Focused Rehabilitation (TFR)
Description: Abdominal stabilization progression for TFR is applied with simultaneous breathing exercise for 3 days a week, 45 minutes aday, 8 weeks (24 sessions in total)(8).~1. Basic Abdominal Stabilization Training, Task-Focused Exercises (without spinal diagonal and rotational components)(8,12).~   Warm-up: 5 minutes, Global Stretching and Relaxation(9,10,11). Extremity load, elastic band, and unstable surface are added as stabilization is achieved in neurodevelopmental positions, respectively, without disrupting trunk muscle activation. Task-oriented exercises(12).~   Cooling Down: Warm-up exercises are repeated.~2. General Posture and Asymmetry Training Brochure (includes adolescent, family, and team members)(13-17).~Each exercise starts with 3 seconds and gradually progresses to 10 seconds, 10 repetitions, 3 sets.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Rehabilitation Group (CRG)
Description: The group receives conventional treatment 2 days a week, 40 minutes each session.~1. Normal Joint Movement (NEH)~2. Stretching for the lower, and upper extremities and around the hips~3. Lying activities~4. Curl up (assisted, unaided)~5. Bridging exercise, cat camel exercise, posterior pelvic tilt exercise~6. Walking training~7. Climbing and descending stairs~8. Weight transfer exercises at standing, sitting It is an intervention performed by a physiotherapist who regularly follows up in a special education and rehabilitation center.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Rehabilitation Group (CRG)
Description: The group receives conventional treatment 2 days a week, 40 minutes each session.~1. Normal Joint Movement (NEH)~2. Stretching for the lower, and upper extremities and around the hips~3. Lying activities~4. Curl up (assisted, unaided)~5. Bridging exercise, cat camel exercise, posterior pelvic tilt exercise~6. Walking training~7. Climbing and descending stairs~8. Weight transfer exercises at standing, sitting It is an intervention performed by a physiotherapist who regularly follows up in a special education and rehabilitation center.
Study: NCT05164536

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amyvid
Description: All participants will undergo a single β-amyloid PET scan with Amyvid.
Study: NCT05084261

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BT051 200 mg
Description: Oral BT051 200 mg once daily for 28 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BT051 800 mg
Description: Oral BT051 800 mg once daily for 28 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BT051 3200 mg
Description: Oral BT051 3200 mg once daily for 28 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo
Description: Placebo Matching BT051
Study: NCT04378634

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Sub-maximal exercise test

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Sub-maximal exercise test

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Sub-maximal exercise test

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Sub-maximal exercise test

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mental Stress Test
Description: Computerised mental arithmetic challenges and social evaluative threat tasks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mental Stress Test
Description: Computerised mental arithmetic challenges and social evaluative threat tasks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mental Stress Test
Description: Computerised mental arithmetic challenges and social evaluative threat tasks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mental Stress Test
Description: Computerised mental arithmetic challenges and social evaluative threat tasks