TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06596837

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality
Description: The investigators manipulated the following two variables within the experimental design:~Immersion in the virtual environment. This was a nominal variable with two levels: a low-immersive environment (Other group) and a highly immersive environment (Experimental group) using the Cold River application.~Order of virtual reality (VR) deployment during the first session. This was also a nominal variable with two levels: VR during the first part of the dressing change (removing the dressing) and VR during the second part of the dressing change (cleaning the wound and applying a new dressing). In each subsequent session, the order of VR deployment was swapped for each participant.~The values of both variables were assigned to participants according to their numbers (e.g., 1. highly immersive, VR first; 2. low immersive, VR first; 3. highly immersive, VR last; 4. low immersive, VR last, etc.).

Intervention type: DEVICE
Group type: OTHER
Intervention: virtual reality
Description: The investigators manipulated the following two variables within the experimental design:~Immersion in the virtual environment. This was a nominal variable with two levels: a low-immersive environment (Other group) and a highly immersive environment (Experimental group) using the Cold River application.~Order of virtual reality (VR) deployment during the first session. This was also a nominal variable with two levels: VR during the first part of the dressing change (removing the dressing) and VR during the second part of the dressing change (cleaning the wound and applying a new dressing). In each subsequent session, the order of VR deployment was swapped for each participant.~The values of both variables were assigned to participants according to their numbers (e.g., 1. highly immersive, VR first; 2. low immersive, VR first; 3. highly immersive, VR last; 4. low immersive, VR last, etc.).
Study: NCT06597071

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: NeuraLight PD
Description: NeuraLight software-based platform for PD patients

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: NeuraLight PSP
Description: NeuraLight software-based platform for PSP patients

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: NeuraLight MSA
Description: NeuraLight software-based platform for MSA patients

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: NeuraLight
Description: NeuraLight software-based platform
Study: NCT06591611

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PEEK reinforced fixed all-on-four prosthesis
Description: Fabricating a fixed prosthesis for patients with completely edentulous mandibles reinforced with PEEK

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEEK reinforced fixed all-on-four prosthesis
Description: Fabricating a fixed prosthesis for patients with completely edentulous mandibles reinforced with PEEK
Study: NCT06601023

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychosocial intervention
Description: The PM+MiLE is a low-intensity intervention. The intervention will cover relevant aspects of brief mindfulness, legal education, awareness of human rights and challenges of complaint, including support. The problem management ambit will include understanding adversity, managing stress, managing problems, getting going and keep doing, strengthening social support and staying well and looking forward, including positive behaviour modification.The intervention will also incorporate child development and building positive parenting interactions with children.
Study: NCT06600646

Intervention type: DIAGNOSTIC_TEST
Intervention: Bronchoscopy
Description: Bronchoscopy will be performed in patients with refractory or unexplained chronic cough and healthy controls.

Intervention type: DIAGNOSTIC_TEST
Intervention: Bronchoscopy
Description: Bronchoscopy will be performed in patients with refractory or unexplained chronic cough and healthy controls.
Study: NCT06597669

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Placement of stainless steel crowns on primary molars
Description: Preformed metal crowns have been placed to treat caries in primary molars

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Placement of stainless steel crowns on primary molars
Description: Preformed metal crowns have been placed to treat caries in primary molars
Study: NCT06594874

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10370
Description: HS-10370 administered orally every day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10370
Description: HS-10370 administered orally every day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10370
Description: HS-10370 administered orally every day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10370
Description: HS-10370 administered orally every day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10370
Description: HS-10370 administered orally every day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Administered intravenously every 21 days; dose by label.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Administered intravenously every 21 days; dose by label.
Study: NCT06588036

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotic
Description: . The primary outcome measure will be the mean time from the initiation of treatment to the resolution of diarrhea symptoms. This objective seeks to provide evidence-based insights into the optimal management strategies for childhood diarrhea and inform clinical practice guidelines.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotic
Description: . The primary outcome measure will be the mean time from the initiation of treatment to the resolution of diarrhea symptoms. This objective seeks to provide evidence-based insights into the optimal management strategies for childhood diarrhea and inform clinical practice guidelines.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Duration
Description: every participant is alloted a group based on RCT.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Smecta
Description: Group 4 will be given smecta scahet
Study: NCT06587815

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: musical starry sky projector
Description: Children in intervention group received musical starry sky projector during their sleep time
Study: NCT06599593

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: SQ-LNS
Description: CHW provides all children ages 6-24 months who do not have acute malnutrition with SQ-LNS (Enov'nutributter; Nutriset; 20 g/day, approximately 100-120 calories).

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: SQ-LNS
Description: CHW provides all children ages 6-24 months who do not have acute malnutrition with SQ-LNS (Enov'nutributter; Nutriset; 20 g/day, approximately 100-120 calories).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated Nutritional Screening
Description: In conjunction with SMC administration, CHWs screen children for MUAC. CHW refers children with MUAC \&lt;12.5 to the CSPS for MAM/SAM care and to receive all standard nutritional program.
Study: NCT06591845

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ziresovir 125 mg
Description: Active Substance: Ziresovir, Pharmaceutical Form: Suspension, Route of Administration: Oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ziresovir 500 mg
Description: Active Substance: Ziresovir, Pharmaceutical Form: Suspension, Route of Administration: Oral

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Active Substance: Placebo, Pharmaceutical Form: Suspension, Route of Administration: Oral

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin hydrochloride tablet 400 mg
Description: Active Substance: Moxifloxacin hydrochloride Pharmaceutical Form: Tablet Route of Administration: Oral
Study: NCT06591247

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Double Baloon Catheter
Description: A double Baloon Catheter will be inserted for 12 hours to one of the arms of the study

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Membrane Stripping
Description: Stripping will be considered as 3-5 rotations of separating the amniotic sac from the cervix and will be perfomed twice (every 4-6 hours)
Study: NCT06597500

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3923868
Description: GSK3923868 will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3923868
Description: GSK3923868 will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Itraconazole will be administered.
Study: NCT06494449

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Higher protein
Description: An acute mixed meal containing higher protein

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lower protein
Description: An acute mixed meal containing lower protein
Study: NCT06594861

Intervention type: OTHER
Intervention: No intervention
Description: No intervention.

Intervention type: OTHER
Intervention: No intervention
Description: No intervention.
Study: NCT06592326

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 9MW2821
Description: 9MW2821, 1.25mg/kg, intravenous (IV) infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Toripalimab, 240mg, intravenous (IV) infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gemcitabine
Description: Gemcitabine: 1000mg/m2, intravenous (IV) infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin/Carboplatin
Description: Cisplatin: 70mg/m2 or Carboplatin: AUC=4.5/5, intravenous (IV) infusion.
Study: NCT06604156

Intervention type: DEVICE
Intervention: EEG monitoring
Description: During gastrointestinal endoscopy, electroencephalogram (EEG) monitoring will be conducted using qCON and qNOX technologies to assess patients\&amp;amp;#39; sedation and analgesia status while they undergo painless gastrointestinal endoscopy. This will be combined with visual assessments (such as cough reflex, respiratory depression, and limb movement) and clinical physiological monitoring (including vital signs and pulse oximetry) to explore and establish a stable and optimal depth of sedation for anesthesia.

Intervention type: DEVICE
Intervention: EEG monitoring
Description: During gastrointestinal endoscopy, electroencephalogram (EEG) monitoring will be conducted using qCON and qNOX technologies to assess patients\&amp;amp;#39; sedation and analgesia status while they undergo painless gastrointestinal endoscopy. This will be combined with visual assessments (such as cough reflex, respiratory depression, and limb movement) and clinical physiological monitoring (including vital signs and pulse oximetry) to explore and establish a stable and optimal depth of sedation for anesthesia.
Study: NCT05482971

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropeginterferon alfa-2b-njft (P1101)
Description: Ropeginterferon alfa-2b-njft (P1101)
Study: NCT06590155

Intervention type: DRUG
Group type: OTHER
Intervention: Erythropoietin
Description: the role of erythropoietin in improving neonatal hypoxic ischemic encephalopathy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Erythropoietin
Description: the role of erythropoietin in improving neonatal hypoxic ischemic encephalopathy
Study: NCT06597799

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MRT-6160
Description: Orally administered tablets of MRT-6160

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MRT-6160
Description: Orally administered tablets of MRT-6160

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Orally administered tablets of placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Orally administered tablets of placebo
Study: NCT05156385

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sample for the determination of antihypertensives or their metabolites.
Description: 15 ml of Blood sample for the determination of antihypertensives or their metabolites

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaire on sexual activity
Description: Questionnaire on sexual activity in women

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Scale on hospital anxiety and depression
Description: Scale on hospital anxiety and depression to detect anxious and depressive symptoms (14 questions)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Morisky Questionaire
Description: anti-hypertensive medication compliance questionnaire
Study: NCT06591130

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Youth culturally adapted manual assisted psychological intervention (Y-CMAP)
Description: YCMAP (Youth culturally adapted manual assisted psychological intervention) is based on CBT principles. It comprises of 8-10 sessions delivered individually over 3 months (weekly for 1 month then fortnightly), lasting for 60 minutes. The intervention includes psycho-education and a comprehensive cognitive behavioural assessment of the self-harm attempt using virtual stories of four young people. Therapists and young person choose from a list of techniques those which are most relevant to the young person's problems. Therapy is therefore adapted to fit with the young person's problems and primarily utilises problem solving, CBT, and dialectical therapy strategies to bring about change. To help determine the most appropriate coping strategy a coping tree is designed. Training in assertiveness and anger management are offered to help the young person to develop resilience to cope with stress.
Study: NCT06587425

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM-302+Candonilimab+Capecitabine
Description: LM-302: 1.8mg/kg ivgtt d1, q2w; Canonilimab: 6mg/kg ivgtt d1, q2w; Capecitabine: 1000mg/m\^2 po bid d1-10, q2w.
Study: NCT06596278

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Memesto
Description: Memesto wearable audio player
Study: NCT06474832

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-intensity interval training
Description: Training on a stationary bike and integrated with exergame (Jbike, JACFIT, USA), the exercise games connect to a map in the app through sensors, allowing players from different countries to ride together and complete the map, thus increasing the diversity of the training, including a warm-up and cool-down at 30% HRR for 5 minutes each. Perform HIIT with 5 intervals at 80% heart rate reserve (HRR), each interval lasting 4 minutes, with 3-minute intervals at 40% HRR between each interval.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Moderate intensity continuous training
Description: Training on a stationary bike and integrated with exergame (Jbike, JACFIT, USA), the exercise games connect to a map in the app through sensors, allowing players from different countries to ride together and complete the map, thus increasing the diversity of the training, including a warm-up and cool-down at 30% HRR for 5 minutes each. Perform continuous exercise at 59% HRR for 35 minutes.
Study: NCT06604091

Intervention type: OTHER
Intervention: Treatment protocol
Description: The treatment protocols of ovarian stimulation include long protocol and antagonist protocol. The protocols for frozen embryo transplantation include natural protocol, mild ovarian stimulation, hormone replacement treatment (HRT) protocol and down-regulation combining with HRT protocol. The treatment protocols are refined in above protocols. Treatment of patients follow the principle of clinical practice in real world.

Intervention type: OTHER
Intervention: Treatment protocol
Description: The treatment protocols of ovarian stimulation include long protocol and antagonist protocol. The protocols for frozen embryo transplantation include natural protocol, mild ovarian stimulation, hormone replacement treatment (HRT) protocol and down-regulation combining with HRT protocol. The treatment protocols are refined in above protocols. Treatment of patients follow the principle of clinical practice in real world.

Intervention type: OTHER
Intervention: Treatment protocol
Description: The treatment protocols of ovarian stimulation include long protocol and antagonist protocol. The protocols for frozen embryo transplantation include natural protocol, mild ovarian stimulation, hormone replacement treatment (HRT) protocol and down-regulation combining with HRT protocol. The treatment protocols are refined in above protocols. Treatment of patients follow the principle of clinical practice in real world.

Intervention type: OTHER
Intervention: Treatment protocol
Description: The treatment protocols of ovarian stimulation include long protocol and antagonist protocol. The protocols for frozen embryo transplantation include natural protocol, mild ovarian stimulation, hormone replacement treatment (HRT) protocol and down-regulation combining with HRT protocol. The treatment protocols are refined in above protocols. Treatment of patients follow the principle of clinical practice in real world.
Study: NCT05458713

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Laser acupuncture
Description: Irradiate acupoints with low power laser

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Laser acupuncture
Description: Irradiate acupoints with low power laser

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Laser acupuncture
Description: Irradiate acupoints with low power laser

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Laser acupuncture
Description: Irradiate acupoints with low power laser

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Laser acupuncture
Description: Irradiate acupoints with low power laser
Study: NCT05782452

Intervention type: PROCEDURE
Intervention: Ophthalmic examination
Description: Facial photographs of the participants were obtained at the time of enrolment. Pre- and post-operative anterior eye segment photographs were obtained under diffuse, direct focal and retro illumination. Clinical data, including basic information, family history, and comprehensive pre- and post-operative ophthalmic examination findings, were recorded.

Intervention type: GENETIC
Intervention: Whole-exome sequencing
Description: Performing whole-exome sequencing and bioinformatics analysis.
Study: NCT05458713

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Laser acupuncture
Description: Irradiate acupoints with low power laser
Study: NCT06448117

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mind Nutrition
Description: The 6-month nutrition intervention includes two individual and three group dietary counseling sessions. During the first individual meeting, a research dietitian will assess the participants' diet quality and eating habits, and each participant will set personal goals in cooperation with the research dietitian. At the second individual meeting, the attainment of the goals will be evaluated, and potential challenges and solutions discussed. Each group session has its theme and content in the following chronological order:~1. Introduction to the theme and importance of a regular meal frequency~2. Principals of health-promoting diet, mindful eating~3. Successful eating regulation skills, psychology of the long-term lifestyle changes.~Additionally, participants receive home assignments and a workbook containing informational material and exercises.
Study: NCT05801120

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketogenic food products
Description: Participants will be given a ketogenic food product prior to the hyperbaric oxygen exposure.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketogenic food products
Description: Participants will be given a ketogenic food product prior to the hyperbaric oxygen exposure.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketogenic food products
Description: Participants will be given a ketogenic food product prior to the hyperbaric oxygen exposure.
Study: NCT05609487

Intervention type: OTHER
Group type: OTHER
Intervention: As usual
Description: Patients included in the control phase, i.e. without intervention, will be asked not to oppose participation in the research, after having received the presentation of the study and the information notice. The data collection will be similar to the data collection during the intervention period.

Intervention type: DEVICE
Group type: OTHER
Intervention: Protection plan
Description: The intervention consists of making the protection plan in a co-constructed process with the care user. This tool is built in 6 steps, is written and takes 20 to 40 minutes to complete.~These 6 steps allow to identify the first signs of a suicidal crisis and to identify different strategies to face it. They are constructed in an ascending order, with the aim of being used by the care user in an autonomous situation.
Study: NCT05423210

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Atezolizumab + FSRT radiation
Description: Atezolizumab 840mg IV every 2 weeks Fractionated Stereotactic Radiotherapy