TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05701800

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1468
Description: Sterile liquid dispersion for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1468
Description: Sterile liquid dispersion for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1468
Description: Sterile liquid dispersion for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1468
Description: Sterile liquid dispersion for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1468
Description: Sterile liquid dispersion for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Sterile liquid for injection
Study: NCT05597514

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D printed educational model
Description: Slide-based presention plus 3D printed airway suction model

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tranditional model education
Description: Slide-based presention plus tranditional model
Study: NCT05242146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GB5121
Description: Capsule containing GB5121
Study: NCT06538714

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MIIT
Description: 12-week supervised exercise program consisting of moderate-intensity interval training (MIIT)~MIIT: 3 series of 4-8 repetitions of 30-s of work at 70-75% of MAS and 30-s of active recovery at 50% of MAS.~3 exercise sessions per week.~Additionally, participants receive no individualized nutritional counseling.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MIIT + HIIT
Description: 12-week supervised exercise program consisting of moderate-intensity interval training (MIIT) (6-week) and high-intensity interval training (HIIT) (6-week).~MIIT: 3 series of 4-8 repetitions of 30-s of work at 70-75% of MAS and 30-s of active recovery at 50% of MAS.~HIIT: 3 series of 5 repetitions of 30-s of work at 100% of MAS and 30-s of active recovery at 50% of MAS for weeks 7-9, as well as two series of 10 repetitions of 30-s of work at 100% of MAS and 30-s of active recovery at 50% of MAS for weeks 10-12.~3 exercise sessions per week. Additionally, participants receive no individualized nutritional counseling.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: Habitual physical activity No additional physical intervention~Additionally, participants receive no individualized nutritional counseling.
Study: NCT06539689

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sperstent® peripheral spot stent system
Description: Sperstent® peripheral spot stent system, Percutaneous Transluminal Angioplasty (PTA), Digital Subtraction Angiography（DSA）

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Everflex® self-expanding peripheral stent system
Description: Everflex® self-expanding peripheral stent system, Percutaneous Transluminal Angioplasty (PTA), Digital Subtraction Angiography（DSA）
Study: NCT04877535

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ML-based report card
Description: PACU and ward providers caring for participants will be notified by Anesthesia Control Tower clinicians before arrival if the patient's report card. The notification will contain a report card of the patient's forecast risk of major adverse events, explanatory machine-learning outputs, most influential pre- and intraoperative data, and predicted treatments.The ML risk profile generated for each patient will include risk of 30 day mortality, risk of respiratory failure, risk of acute kidney injury, and risk of postoperative delirium
Study: NCT05701800

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Shingrix
Description: Sterile suspension for injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Shingrix
Description: Sterile suspension for injection
Study: NCT05315388

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Immersion therapy in nature - Vitamin N
Description: Usual therapy group The first saliva sample will be taken upon awakening to determine cortisol concentration. At their workplace, they will be asked to remain seated and silent for 3 minutes, the following will be taken: blood pressure, heart rate, psychological instruments (stress-anxiety), blood sample.~Group 2A and Group 2B In the natural environment, a saliva sample will be taken upon awakening to determine cortisol concentration. After arrival at the site, they will be asked to remain seated and silent for 3 minutes, the following will be taken: blood pressure, heart rate, psychological instruments (stress-anxiety), blood sample.~The first phase is a session of observation of the site for 15 minutes. A slow, unhurried walk will be performed for 1 hour and 45 minutes. The order of activities (sitting and walking) will be established to ensure reliability of physiological measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Immersion therapy in nature - Vitamin N
Description: Usual therapy group The first saliva sample will be taken upon awakening to determine cortisol concentration. At their workplace, they will be asked to remain seated and silent for 3 minutes, the following will be taken: blood pressure, heart rate, psychological instruments (stress-anxiety), blood sample.~Group 2A and Group 2B In the natural environment, a saliva sample will be taken upon awakening to determine cortisol concentration. After arrival at the site, they will be asked to remain seated and silent for 3 minutes, the following will be taken: blood pressure, heart rate, psychological instruments (stress-anxiety), blood sample.~The first phase is a session of observation of the site for 15 minutes. A slow, unhurried walk will be performed for 1 hour and 45 minutes. The order of activities (sitting and walking) will be established to ensure reliability of physiological measurements.
Study: NCT05154903

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Citicoline 500 MG
Description: Citicoline will be administered in continuous iv infusion in a dose of 2000 mg per day for the first week following AIS then by oral route for the next 5 weeks.
Study: NCT05610111

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CLC + BAM
Description: Closed Loop Control with the Behavioral Adaption Module for 4 weeks

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CLC + BAM
Description: Closed Loop Control with the Behavioral Adaption Module for 4 weeks

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CLC + ABC
Description: Closed Loop Control with Adaptive Biobehavioral Control for 16 weeks

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CLC + ABC
Description: Closed Loop Control with Adaptive Biobehavioral Control for 16 weeks
Study: NCT06240897

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CURATE.Dtx
Description: CURATE.Dtx is a self-guided digital multitasking game that involves a combination of four subtasks played simultaneously, targeting different cognitive domains.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optional games
Description: The patient will first be asked how he/she feels and what they have done that day. The patient then selects a digital local pet (dog, cat, bird) and can customize its appearance, name and background location. The player can interact with their pet via several actions such as feed, bathe, train and accessorize. Playing with digital pets can help reduce stress and anxiety in the elderly. It can be a positive distraction in alleviating the elderly's worries and discomforts. In order to purchase accessories for their digital pet, they are encouraged to play short games that include Grocery Snap, Down Memory Lane and Pet Escape. These games are aimed at improving memory and reduce cognitive decline.
Study: NCT06119737

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Effects of exercises on TSH levels

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Effects of exercises on TSH levels

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Effects of exercises on TSH levels

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Effects of exercises on TSH levels
Study: NCT06542809

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire
Description: Recruitment will take place through routine paediatric endocrinology consultations with physicians registered with BELSPEED. These doctors will take the time to explain the questionnaire. And allow the patient to complete it.
Study: NCT06346561

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: the reduction of controlled hypotension and the control of hemodynamic responses of the body

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: the reduction of controlled hypotension and the control of hemodynamic responses of the body

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Labetalol
Description: the reduction of controlled hypotension and the control of hemodynamic responses of the body

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Labetalol
Description: the reduction of controlled hypotension and the control of hemodynamic responses of the body
Study: NCT06224829

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pain Inducing Massage
Description: 60 seconds of direct pressure to the neck resulting in 5/10 pain . This will be repeated four times for a total of 240 seconds

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pain Free Massage
Description: 60 seconds of direct pressure to the neck resulting in 0/10 pain . This will be repeated four times for a total of 240 seconds

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cold Water Bath
Description: Participants will place their hand in a cold water bath maintained at 6 to 8 degrees Celsius for 60 seconds. This will be repeated four times for a total of 240 seconds.
Study: NCT06222255

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transanal Irrigation (TAI)
Description: The combination of transanal irrigation (TAI) and Loperamide (Lopmin®) involves administering Loperamide orally, with a daily dosage of 2 mg for males (2 tablets once daily) and 1 tablet for females (1 tablet once daily). This is complemented by the use of TAI, a method in which patients self-administer water into the rectum through an enema, aiming to enhance bowel management and potentially alleviate symptoms associated with LARS (Low Anterior Resection Syndrome).
Study: NCT05081739

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Prospera Transplant Assessment
Description: Prospera™ detects allograft rejection noninvasively and with high accuracy by measuring the fraction of dd-cfDNA in the patient's blood, without the need for prior donor or recipient genotyping.~Prospera is a commercially available LDT developed by Natera, Inc. Natera is a laboratory certified under the Clinical Laboratory Improvement Amendments (CLIA).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endomyocardial biopsy
Description: Subjects will undergo surveillance EMB per the institution's standard clinical care, which is expected to be approximately every other week in months 2 and 3, then monthly through month 6, then every 1-3 months through the end of month 12.
Study: NCT05263869

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MRG002
Description: Administrated intravenously
Study: NCT05420636

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iadademstat
Description: Patients will be treated with iadademstat given at a dose of 150 microgram PO administered on a 5 day on-2 day off schedule every week (days 1 through 21)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Patients will be treated with Paclitaxel given at a dose of 80 mg/m2 intravenous administration weekly day 1, 8 and 15 (days 1 through 21).
Study: NCT05021120

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK127
Description: Subjects will receive AK127 by intravenous administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: After AK127 infusion, on the same day subjects will receive AK104 by intravenous administration
Study: NCT06620016

Intervention type: DIAGNOSTIC_TEST
Intervention: Circulating microRNAs.
Description: Pre and post-surgery evaluation of peripheral blood circulating microRNAs levels.

Intervention type: DIAGNOSTIC_TEST
Intervention: Circulating microRNAs.
Description: Pre and post-surgery evaluation of peripheral blood circulating microRNAs levels.
Study: NCT05814510

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asthma CHAMPS full program
Description: Full program includes (1) education for staff, students, and caregivers (2) environmental education and intervention (3) asthma care coordination (4) resources

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asthma CHAMPS full program
Description: Full program includes (1) education for staff, students, and caregivers (2) environmental education and intervention (3) asthma care coordination (4) resources

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asthma CHAMPS full program
Description: Full program includes (1) education for staff, students, and caregivers (2) environmental education and intervention (3) asthma care coordination (4) resources

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asthma CHAMPS Wait List Control
Description: Stepped wedge design
Study: NCT05543213

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Action Observation Therapy
Description: A video clip of a series of exercises is shown to the patients, then they practice them according to mirror neurons and observational learning.
Study: NCT06008925

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell))
Description: Intratumoral injection only. Dosing days may be Day 1 or Days 1-3 only.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab Injection
Description: Administered once at 3 mg/kg intravenously on Days 8 and 22 of each cycle.
Study: NCT04947033

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TJ210001 Injection
Description: The test drug TJ210001 will be preset with 5 escalation dose levels: 0.3mg/kg, 1mg/kg, 3mg/kg, 10mg/kg and 15mg/kg, administered once a week.
Study: NCT05814510

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asthma CHAMPS Wait List Control
Description: Stepped wedge design
Study: NCT05108181

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle typology + exercise training
Description: Exercise training: Participants perform 9 weeks of strength training at 60% of their 1RM.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle typology + exercise training
Description: Exercise training: Participants perform 9 weeks of strength training at 60% of their 1RM.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle typology + training frequency
Description: Training frequency: leg A and arm A of the participants train 3 times per week, leg B and arm B train 2 times per week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle typology + training frequency
Description: Training frequency: leg A and arm A of the participants train 3 times per week, leg B and arm B train 2 times per week.
Study: NCT04530682

Intervention type: BIOLOGICAL
Intervention: Biological samples
Description: Serum and plasma samples. At baseline, 6, 12 and 24 months
Study: NCT04760470

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Technology-assisted upper extremity rehabilitation
Description: Subjects get 6 weeks of technology-assisted upper extremity rehabilitation
Study: NCT05548244

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Activation Therapy
Description: Participants will be seen for a maximum of 16 sessions of therapy focused on increasing rewarding behaviors (16 individual therapy sessions of 1-hour, 2 of which include the BSIS component) over 16 weeks. BA intervention includes monthly booster sessions offered throughout 6-month follow up. If needed, two extra sessions will be allowed during treatment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baseline assessment procedures
Description: Completion of the K-SADS and CDRS-R to assess MDD, and the Wechsler Abbreviated Scale of Intelligence - 2nd Edition to assess IQ.
Study: NCT05313516

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OKKO Health app
Description: Use of OKKO Health app for home monitoring.
Study: NCT05146128

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strengthening exercises
Description: The participants had to perform specific exercices 3 times a week during 8 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strengthening exercises
Description: The participants had to perform specific exercices 3 times a week during 8 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strengthening exercises
Description: The participants had to perform specific exercices 3 times a week during 8 weeks
Study: NCT05928702

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: temperature-elevating armbath
Description: Hydrotherapeutic Approach
Study: NCT05896358

Intervention type: BEHAVIORAL
Intervention: ketogenic diet
Description: a low calorie ketogenic diet

Intervention type: BEHAVIORAL
Intervention: ketogenic diet
Description: a low calorie ketogenic diet
Study: NCT05606068

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Paxman Limb Cryocompression System (PLCS)
Description: The study population will comprise of cancer patients scheduled to receive weekly paclitaxel chemotherapy for a maximum of 12 cycles.~Cryocompression will be applied during every cycle of chemotherapy for a duration of up to 4 hours. All chemotherapy patients will receive 30 minutes pre-infusion cooling and 30 minutes post-infusion cooling. Cryocompression for each cycle will not exceed 4 hours. Chemotherapy and concomitant limb cryocompression are performed for 12 cycles and may be continued further in consultation with the PI. Overall, limb cryocompression will be administered for no longer than four hours.
Study: NCT05039905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99mTc-MSA-ICG
Description: Intratumoral injection of 99mTechnetium-manosylated albumin-indocyanine green to lung cancer patients
Study: NCT04862091

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abiraterone Acetate Tablets (I)
Description: Abiraterone Acetate Tablets (I)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ZYTIGA®
Description: ZYTIGA®
Study: NCT06573580

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The essential public health service（EPHS）for COPD
Description: Each group plans to recruit 3,000 participants. For the intervention group, the community-based management includes adding COPD management-related content to the primary public health service. This includes: Providing at least four follow-ups during the project at the 3rd, 6th, 9th, and 12th months. During each follow-up, patients must complete the COPD Patient Follow-up Questionnaire and receive oral health education and targeted clinical advice from the general practitioner (GP). In addition, the GPs must also distribute educational booklets and materials, record symptom assessment results and acute exacerbation situations, and provide targeted clinical advice and clinical decisions to the COPD patients according to the checklist of Chinese guideline for management of COPD in primary care. At the baseline and the last follow-up, patients need to undergo a routine physical examination, pulmonary function test, and bronchodilator test at their community health centers
Study: NCT05063149

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Broncho-Vaxom
Description: Broncho-Vaxom is a bacterial extract comprising lyophilised fractions of 21 different inactivated bacterial strains, which are frequently causing RTI.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo powder from a capsule will be given, which will be indistinguishable from the active study drug.
Study: NCT06694974

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: APP calculation for FIB-4
Description: the investigators plan to use the smartphone App for FIB-4 calculation and notify the patients.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Standard Care (in control arm)
Description: The standard group proceeds as regular practice
Study: NCT06696313

Intervention type: DEVICE
Group type: OTHER
Intervention: Insignia
Description: * Insignia hip stem~* Trident hemispherical shell~* X3 polyethylene liner~* Metal or ceramic head
Study: NCT05729022

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound microendoscopic technique
Description: Ultrasound-guided microendoscopic lumbar transforaminal epidural steroid injection

Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Fluoroscopy
Description: Fluoroscopy-guided lumbar transforaminal epidural steroid injection.
Study: NCT05301933

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Parent Training (BPT)
Description: BPT is an evidence-based psychosocial intervention that is directed exclusively to parent of children with ADHD and related disorders. BPT focuses on instructing parents to use approaches to enhance the parent-child relationship (e.g., quality time, praise) and proactive discipline strategies (e.g., time out, reward systems) to reduce challenging child behavior.
Study: NCT06569043

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breakfast Bar
Description: Packaged breakfast bar product available in retail stores
Study: NCT05381792

Intervention type: DIAGNOSTIC_TEST
Intervention: Bacterial gene markers test
Description: Bacterial gene markers test using qPCR
Study: NCT06572969

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Elastic-Resistance Kick Training
Description: Athletes used tailored Elastic Resistance training

Intervention type: OTHER
Group type: OTHER
Intervention: No Elastic-Resistance Kick Training
Description: Regular Taekwondo regimen without Elastic Resistance training
Study: NCT06574373

Intervention type: OTHER
Group type: OTHER
Intervention: Blood Collection Protocol for Patients with Indolent, Invasive, and Pancreatic Cancer-Associated IPMN Based on Clinical Course and Surgical Intervention
Description: Blood will be collected from patients with indolent IPMN, invasive IPMN, and IPMN associated with pancreatic cancer, depending on their clinical course. Patients with indolent IPMN will be monitored by the gastroenterology units of their respective institutions, which will inform the patient. Patients with invasive IPMN and/or associated with cancer will undergo surgical resection as part of their standard clinical care, and blood will be collected after informed consent is obtained by the surgical teams at each institution.