TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06582979

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Computer-Based Game Therapy
Description: Computer-based game intervention will be done three times a week, every morning before school lessons begin or during break time. Researchers will give a brief explanation of the rules on how to play the game before the intervention begins. In the game, participants will act as a fruit truck delivery driver and will have to sort out fruit delivery to different houses according to the instructions of the game. For example, the instruction starts with delivering a yellow-colored banana to a house with a red-colored roof, or delivering a purple-colored grape to a house with a blue-colored roof. Participants will first have to finish a minimum of three tutorial rounds reaching ≥75% correct delivery. Instructions will be divided into four stages; visual stimulus, auditory stimulus, visual stimulus with an obstacle, auditory stimulus with an obstacle. Each round will last for 2 minutes. Total time needed to complete a single computer-based intervention session is around 30-45 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-Intensity Interval Training
Description: HIIT will be done two times a week during physical education hours (in the school's sports field) led by the school's physical education teacher and also certified physical trainers who have undergone training supervised by a sports medicine physician. Before the start of each HIIT session, participants will have their pulse rate assessed with a pulse oximetry and then undergo warm-up for 5 minutes. The duration of each HIIT session will be continuously extended starting at around 4 minutes (1 tabata block/8 moves) during the first week to 8 minutes (2 tabata block/16 moves) during the final week. A single tabata block moveset incorporates 8 total moves; squat jump, push up, high skipping, burpees, isometric front plank, multi jumps on bench, mountain climber in hand plank and lateral sprint (5m). Each move will be done for 20 seconds, followed by a 10 second rest. Pulse rate will be assessed again after the HIIT session and then participants will undergo cooling down and relaxation.
Study: NCT06322784

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oat bran (dietary fiber)
Description: Dietary fiber, known as the seventh type of nutrients, refers to carbohydrate polymers that have health benefits for the human body, mainly derived from plant cell walls such as grains, fruits, and vegetables.Mediterranean cuisine is a dietary pattern
Study: NCT06581458

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: tDCS
Description: The immediate intervention group will continue to receive five tDCS treatments per week for 6 months. The late intervention group will receive five sham treatments per week for 3 months and then begin receiving five weekly tDCS treatments for an additional 3 months.
Study: NCT06255535

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active iTBS treatment
Description: Participants will undergo three iTBS sessions per day, with 1800 pulses per session, over a 12-week period. Individualized targets will be generated using the pBFS technique.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham iTBS treatment
Description: Participants will undergo three iTBS sessions per day, with 1800 pulses per session, over a 12-week period. Sham stimulation will be delivered through a sham coil with the identical appearance as real coil. Individualized targets will be generated using the pBFS technique.
Study: NCT06378320

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App access and Text message
Description: Access to App and Text messages with app related breastfeeding related question

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App access and Text message
Description: Access to App and Text messages with app related breastfeeding related question

Intervention type: OTHER
Group type: OTHER
Intervention: App access only
Description: Access to App without Text messages with app related breastfeeding related question

Intervention type: OTHER
Group type: OTHER
Intervention: App access only
Description: Access to App without Text messages with app related breastfeeding related question
Study: NCT06098976

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual toothbrush
Description: Manual toothbrush: The patients were taught to use the modified vertical method, and the patient brushed the teeth of the upper and lower jaws using traditional toothbrushes (Diamond, JolleyDent, Damascus, Syria), and anti-plaque toothpaste (Elgydium, UniPharma Co., Ltd, Ashrafiyat Sahnaya, Syria).
Study: NCT04914182

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: LASER
Description: Laser will be applied in specific points for perineal lacerations.

Intervention type: RADIATION
Group type: SHAM_COMPARATOR
Intervention: CONTROL
Description: A control group of sham laser will create for the patients the impression that laser is being played, with the lights of the instrument of on mode turned on, without biological effects.
Study: NCT06581458

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tDCS
Description: The immediate intervention group will continue to receive five tDCS treatments per week for 6 months. The late intervention group will receive five sham treatments per week for 3 months and then begin receiving five weekly tDCS treatments for an additional 3 months.
Study: NCT06583070

Intervention type: RADIATION
Intervention: Radiation therapy
Description: Administer radiation therapy to achieve as complete coverage as possible of all identifiable primary and metastatic lesions in conjunction with targeted and immunotherapy
Study: NCT05959278

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App for vestibular rehabilitation
Description: This app is a platform for performing conventional vestibular rehabilitation remotely

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App for vestibular rehabilitation
Description: This app is a platform for performing conventional vestibular rehabilitation remotely
Study: NCT04941092

Intervention type: OTHER
Intervention: no intervention
Description: no intervention, retrospective comparison
Study: NCT06094075

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance training based on DSI value
Description: The intervention consist of modifying the ongoing resistance exercises. Those with low DSI values will perform ballistics, explosive exercises. Those with high DSI will perform heavy-load training. The resistance training program will consist of 2 sessions per week for 5 weeks (10 sessions in total). The sessions will be separated by a minimum of 48 hours. The strength training group will consist mostly of exercises with high load, whereas the ballistic training group will perform ballistic exercises with low load or without any additional load. The training principle will be the same for both subgroups, consisting of 3 exercises per training session and a total of 6 exercises per week, with four of the exercises being bilateral, one unilateral, and one quasi-unilateral (Bulgarian split squat and scissor jumps).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Normal training group
Description: The participants will do a general training program (not based on DSI values). The resistance training program will consist of 2 sessions per week for 5 weeks (10 sessions in total). The sessions will be separated by a minimum of 48 hours. The strength training group will consist mostly of exercises with high load, whereas the ballistic training group will perform ballistic exercises with low load or without any additional load. The training principle will be the same for both subgroups, consisting of 3 exercises per training session and a total of 6 exercises per week, with four of the exercises being bilateral, one unilateral, and one quasi-unilateral (Bulgarian split squat and scissor jumps).
Study: NCT05898633

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant fragment of human surfactant protein D (rfhSP-D)
Description: Administration of rfhSP-D
Study: NCT06115525

Intervention type: OTHER
Intervention: mNUTRIC score
Description: The mNUTRIC score is a useful means of gauging the nutritional risk of patients in intensive care. Originally designed for IC unit patients, the score is calculated even when patient cooperation is unfeasible, making it applicable for intubated patients. Information necessary for calculation can be obtained from the patient's kin. The mNUTRIC score (without IL-6) classifies patients according to predefined metrics. The following information is necessary: (1) the patient's age, (2) their APACHE II score, (3) their SOFA score, (4) their comorbidities, and (5) the number of days they were hospitalized before being admitted to ICU.

Intervention type: OTHER
Intervention: mNUTRIC score
Description: The mNUTRIC score is a useful means of gauging the nutritional risk of patients in intensive care. Originally designed for IC unit patients, the score is calculated even when patient cooperation is unfeasible, making it applicable for intubated patients. Information necessary for calculation can be obtained from the patient's kin. The mNUTRIC score (without IL-6) classifies patients according to predefined metrics. The following information is necessary: (1) the patient's age, (2) their APACHE II score, (3) their SOFA score, (4) their comorbidities, and (5) the number of days they were hospitalized before being admitted to ICU.

Intervention type: OTHER
Intervention: NRS-2002
Description: The NRS-2002 score is a tool utilised to measure the nutritional risk of patients in intensive care units. This tool was specifically developed for the purpose of evaluating intensive care unit patients and can be calculated without requiring the patient's active involvement. Additionally, it can be applied to patients who have been intubated and the required information can be sourced from their family members or relatives. The Nutritional Risk Screening (NRS)-2002 assesses a patient's nutritional risk based on five variables: (1) recent unexplained weight loss, (2) appetite, (3) BMI, (4) disease-related stress factors (comorbidities), and (5) age over 70 years which is an additional risk factor.

Intervention type: OTHER
Intervention: NRS-2002
Description: The NRS-2002 score is a tool utilised to measure the nutritional risk of patients in intensive care units. This tool was specifically developed for the purpose of evaluating intensive care unit patients and can be calculated without requiring the patient's active involvement. Additionally, it can be applied to patients who have been intubated and the required information can be sourced from their family members or relatives. The Nutritional Risk Screening (NRS)-2002 assesses a patient's nutritional risk based on five variables: (1) recent unexplained weight loss, (2) appetite, (3) BMI, (4) disease-related stress factors (comorbidities), and (5) age over 70 years which is an additional risk factor.
Study: NCT05320172

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Autologous platelet rich plasma eye drops
Description: Fifty milliliters of patient's own whole blood will be placed in five 10-ml vacutainer tubes containing anticoagulant-citrate-dextrose solution (1.4 ml) and centrifuged at 200g for 11 min. The upper two layers of the centrifuged blood, the plasma and buffy coat layer will be separated in a sterile manner and diluted to 20 % (v/v) with a sterile saline solution. The final preparation is divided into 5-ml bottles wrapped in aluminum foil for protection from ultraviolet light. The patients are instructed to store these bottles at -20 °C until required. The bottles being used will be maintained under refrigerated conditions at 4 °C.
Study: NCT05831605

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: venipuncture with near-infrared light
Description: with near-infrared light to locate the veins
Study: NCT04773834

Intervention type: OTHER
Group type: OTHER
Intervention: Digital diabetes prevention program (dDPP)
Description: The digital diabetes prevention program is through the Noom app, and the three devices (Fitbit physical activity tracker, Fitbit weight scale, and self-check hemoglobin a1c kit). This is a one year diabetes prevention program where participants will be expected to participate in 5 to 7 interviews over a 18 month period.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital diabetes prevention program (dDPP)
Description: The digital diabetes prevention program is through the Noom app, and the three devices (Fitbit physical activity tracker, Fitbit weight scale, and self-check hemoglobin a1c kit). This is a one year diabetes prevention program where participants will be expected to participate in 5 to 7 interviews over a 18 month period.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adapted dDPP-EHR tool
Description: This is a product of Phase 1 and 2 of this study where participants will receive detailed text messaging regarding their engagement levels in Noom app.
Study: NCT04826640

Intervention type: OTHER
Intervention: Observational
Description: Observational
Study: NCT06583993

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HNF4α srRNA
Description: HNF4α srRNA will be administered intravenously for the treatment of ICC. The dosing regimen is planned for a second dose 14 ± 3 days post-initial treatment, followed by subsequent treatments every 28 ± 7 days, with adjustments made based on patient tolerance and therapeutic response.
Study: NCT05330260

Intervention type: DIAGNOSTIC_TEST
Intervention: neurocognitive test battery
Description: Assessment of the incidence of late postoperative cognitive decline (LPOCD)

Intervention type: DIAGNOSTIC_TEST
Intervention: neurocognitive test battery
Description: Assessment of the incidence of late postoperative cognitive decline (LPOCD)

Intervention type: DIAGNOSTIC_TEST
Intervention: neurocognitive test battery
Description: Assessment of the incidence of late postoperative cognitive decline (LPOCD)
Study: NCT06394414

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YL201
Description: YL201 (High dose, medium dose and low dose; Q3W) in Combination with Serplulimab (4.5mg/kg; Q3W) with or without Platinum(70 mg/m2; Q3W)-based Chemotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YL201
Description: YL201 (High dose, medium dose and low dose; Q3W) in Combination with Serplulimab (4.5mg/kg; Q3W) with or without Platinum(70 mg/m2; Q3W)-based Chemotherapy.
Study: NCT05516355

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction
Description: The MBSR is an 8-week standardized program (Kabat-Zinn,1990).~During the retreat, participants will receive intensive training during 3 days (from 4:00pm to 9pm the first day and from 7 am to 10 pm including breaks, the second and third days), including focused attention on the breath, open monitoring of awareness in body-scanning, prosocial meditation (i.e. loving kindness and compassion) and gentle yoga. Training is delivered by certified instructors by the University of Massachusetts Centre for Mindfulness (https://www.umassmed.edu/cfm/).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction
Description: The MBSR is an 8-week standardized program (Kabat-Zinn,1990).~During the retreat, participants will receive intensive training during 3 days (from 4:00pm to 9pm the first day and from 7 am to 10 pm including breaks, the second and third days), including focused attention on the breath, open monitoring of awareness in body-scanning, prosocial meditation (i.e. loving kindness and compassion) and gentle yoga. Training is delivered by certified instructors by the University of Massachusetts Centre for Mindfulness (https://www.umassmed.edu/cfm/).
Study: NCT06131931

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CLP Intervention
Description: 4 weekly sessions lasting approximately 60 minutes that will be audio recorded for quality assurance. Each couple will be assigned one RA who will serve as their facilitator and guide them through the Connecting Latinxs en Pareja (CLP) sessions. The RA will deliver the appropriate intervention in either Spanish or English at the couple's preference. Sessions will be delivered via zoom (or comparable secure platform), using established procedures from the team's prior studies. Each participant will complete Qualtrics assessments at baseline, 3-, 6- and 9-months post randomization and biological (hair biomarkers for PrEP and ART adherence) and behavioral and psychosocial data collected.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: WP Intervention
Description: 4 weekly sessions lasting approximately 60 minutes that will be audio recorded for quality assurance. Each couple will be assigned one RA who will serve as their facilitator and guide them through the Wellness Promotion (WP) sessions. The RA will deliver the appropriate intervention in either Spanish or English at the couple's preference. Sessions will be delivered via zoom (or comparable secure platform), using established procedures from the team's prior studies. Each participant will complete Qualtrics assessments at baseline, 3-, 6- and 9-months post randomization and biological (hair biomarkers for PrEP and ART adherence) and behavioral and psychosocial data collected.
Study: NCT05852574

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CP-101
Description: CP101 is an investigational oral microbiome drug designed to deliver a complete and functional microbiome to durably repair intestinal dysbiosis, which is being evaluated for the prevention of recurrent CDI.~CP101 contains live microbial communities, derived from rigorously screened human donor stool that is tested, stabilized, characterized, and formulated into capsules designed specifically for delivery into the small bowel for release, to avoid potential degradation by gastric acid.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CP-101 + Placebo
Description: The placebo in this trial will be presented in capsules that are identical in size, smell, texture, and appearance to those of the CP101 capsules. These will be produced by the BWH investigational drug service
Study: NCT05546515

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Suvorexant (dual orexin receptor antagonist)
Description: Participants will be prescribed up to 30 days of SUVO.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be prescribed up to 30 days of placebo medication.
Study: NCT06475365

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sodium chloride gargle
Description: 15mL salt water gargle
Study: NCT06150664

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTX-8371
Description: Intravenous (IV) infusion (0.1-10.0 mg/kg) every two weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTX-8371
Description: Intravenous (IV) infusion (0.1-10.0 mg/kg) every two weeks.
Study: NCT06471595

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component
Description: The PILI Lifestyle Program (PLP) is an adapted 3-month behavioral lifestyle intervention focused on addressing and initiating weight loss in Native Hawaiians and Pacific Islanders (NHPIs). The PLP covers 8 lessons that offer empirically supported strategies (e.g., plate method, stimulus control) based on the social cognitive theory to improve healthy eating, physical activity, and time and stress management across the 3 months. In this study, the PLP will be enhanced with social determinants of health (SDOH) components that address challenges such as access to healthy foods, housing, and employment issues. There will be 4 SDOH activities relevant to participants' needs and lives. These activities will be delivered during the 3-month PLP.
Study: NCT05514158

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48-ADC
Description: RC48 for injection is a novel antibody-drug conjugate, with a her-2-targeting antibody and a microtube inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC98
Description: RC98 is a recombinant humanized IgG1 monoclonal antibody targeting programmed cell death-Ligand 1 (PD-L1)
Study: NCT06180109

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin film coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Empagliflozin film coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Jardiance film-coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Jardiance film-coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin
Study: NCT05629663

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AR guidance with Hololens 2
Description: The AR instructions were developed as a step-by-step guide, utilizing the dynamic 365 Guide (Software, Microsoft Corporation, Redmond, WA, USA). The AR instructions were delivered using the Microsoft HoloLens 2.
Study: NCT05096000

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: InterMob: a randomized controlled trial aimed at reducing car use in regular car users
Description: Intermob is a theory- and evidence-based behavioral intervention that combines public transport/bicycle and motivational techniques (action planning, personalized transport advice, goal setting).

Intervention type: OTHER
Group type: OTHER
Intervention: Active control: Air pollution information
Description: The active control intervention is based on a discussion about air pollution, the effects of air pollution on health, the association between air pollution and transport.
Study: NCT05870878

Intervention type: OTHER
Group type: OTHER
Intervention: Standard care
Description: Individual lifestyle consultation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: Individual lifestyle consultation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lifestyle program
Description: Lifestyle program focusing on lifestyle advice, coping with stress and adherence to a healthy(er) lifestyle. This program consists of 3 group sessions and an online platform.
Study: NCT05880498

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Intervention
Description: Self-guided mindfulness training using a customized version of the Healthy Minds app
Study: NCT05407038

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Counseling
Description: Receive call from health coach

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Intervention
Description: Undergo routine exercise

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet-Based Intervention
Description: Receive Android tablet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Complete a qualitative interview

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical Device Usage and Evaluation
Description: Wear Garmin Vivofit and Nonin 3150 WristOx2 pulse oximeter
Study: NCT04307628

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walnut
Description: Study participants will eat 2 ounces of walnuts each day.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Nut-Free
Description: Study participants will not eat nuts.