TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05558878

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ambroxol Oral Product
Description: Drug: Ambroxol (75 mg capsule)~Ambroxol is a mucolytic and expectorant drug. Ambroxol has been approved as lozenges for topical analgesia of sore throat in pharyngitis owing to its local anesthetic properties. Anti-inflammatory properties of ambroxol were confirmed by numerous studies. Ambroxol affect neuronal transduction by blocking (TTX)-resistant Na+ channels (Nav1.8) in small (pain-sensing) dorsal root ganglion neurons more potently than TTX-sensitive channels.
Study: NCT05616936

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: injectable platelet rich fibrin
Description: injectable platelet rich fibrin

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: injectable platelet rich fibrin
Description: injectable platelet rich fibrin

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: injectable platelet rich fibrin
Description: injectable platelet rich fibrin
Study: NCT05304507

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: I-PROTECT model
Description: The I-PROTECT model is based on existing research and knowledge of experts in sport medicine, sport psychology and implementation science, with the involvement of end-users throughout the process. The interdisciplinary intervention includes exercises based on physical and psychological principles of effective injury prevention training, specifically tailored for youth handball players, and support for developing a continuous implementation strategy. The intervention is delivered through a mobile application specifically developed for the I-PROTECT project (the I-PROTECT GO), including coach, player, club administrator, and caregiver modules. Coaches are introduced to the intervention in a workshop, and they will conduct the exercises with their teams during handball practice. Players will have support for conducting exercises on their own, and club administrators for developing an implementation strategy. Caregivers will have tailored information about injury prevention training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: Youth coaches in the control group club will be asked to use injury prevention training available in the coach education material (Ready for handball), i.e., current practice in Sweden.
Study: NCT05012293

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baseline
Description: 5-min urban park video clip (Presented on a TV)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fatigue Manipulation
Description: 20-min 2-back task (Presented on a computer)
Study: NCT06149858

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hernioplasty
Description: ventral hernia repair with mesh

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hernioplasty
Description: ventral hernia repair with mesh
Study: NCT06118060

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupressure
Description: In this study, the frequency of acupressure was twice a day (the interval between each acupressure was more than 6 hours, 6:00 to 9:00 in the morning and 1:00 to 4:00 in the afternoon); the acupressure was applied from the first day after surgery for a total of 5 days, that is, each patient received a total of 10 acupressure; the duration was 5 minutes, and the bilateral acupressure required 10 minutes.
Study: NCT05166304

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rebamipide
Description: patients will receive the standard therapy plus 100 mg Rebamipide three times daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: patients will receive the standard therapy (methotrexate) plus placebo tablets
Study: NCT06392880

Intervention type: OTHER
Group type: OTHER
Intervention: Floss Band
Description: A floss band will be applied to the ankle joint and the participant will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Floss Band
Description: A floss band will be applied to the ankle joint and the participant will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Floss Band
Description: A floss band will be applied to the ankle joint and the participant will practice various weight-bearing active ankle motions simultaneously.
Study: NCT05583318

Intervention type: OTHER
Intervention: Data collection
Description: Data from hematological malignancy registries
Study: NCT06392880

Intervention type: OTHER
Group type: OTHER
Intervention: Mulligan Mobilization
Description: Mulligan mobilization will be applied to the ankle joint and the participant will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan Mobilization
Description: Mulligan mobilization will be applied to the ankle joint and the participant will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan Mobilization
Description: Mulligan mobilization will be applied to the ankle joint and the participant will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: Participants will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Participants will practice various weight-bearing active ankle motions simultaneously.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Participants will practice various weight-bearing active ankle motions simultaneously.
Study: NCT05946473

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gum base containing xylitol and essencial oils
Description: Participants will be asked to chew 2 pieces of chewing gum containing additives for 10 minutes after eating in the morning, and after one meal in the evening, for a four-week period

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Gum base with no additives
Description: Participants will be asked to chew 2 pieces of pure gum base for 10 minutes after eating in the morning, and after one meal in the evening, for a four-week period
Study: NCT05840081

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk or yogurt beverage
Description: Commercially available milk or yogurt (depending on experimental arm) will be incorporated into flavored drinks/smoothies to minimize perceived differences among these items, preserving the double-blind nature of the study design.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk or yogurt beverage
Description: Commercially available milk or yogurt (depending on experimental arm) will be incorporated into flavored drinks/smoothies to minimize perceived differences among these items, preserving the double-blind nature of the study design.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk or yogurt beverage
Description: Commercially available milk or yogurt (depending on experimental arm) will be incorporated into flavored drinks/smoothies to minimize perceived differences among these items, preserving the double-blind nature of the study design.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk or yogurt beverage
Description: Commercially available milk or yogurt (depending on experimental arm) will be incorporated into flavored drinks/smoothies to minimize perceived differences among these items, preserving the double-blind nature of the study design.
Study: NCT05583318

Intervention type: OTHER
Intervention: Questionnaires
Description: 9 questionnaires were sent out:~1. QLQ-C30 and SF-12 Quality of Life Questionnaire.~2. Oral quality of life questionnaire QLQ-OH15~3. Sexuality questionnaire SHQ-C22~4. Anxiety and depression questionnaire HADS,~5. Rosenberg Self-Esteem Questionnaire~6. RNLI Reintegration to Normal Life Questionnaire~7. Social Support Questionnaire SSQ6,~8. Socio-economic status questionnaire EPICES,~9. Complementary questionnaire collecting data on socio-professional status.
Study: NCT05110677

Intervention type: DEVICE
Intervention: Multispectral Optoacoustic Tomography (MSOT)
Description: non-invasive transcutaneous imaging of subcellular muscle components
Study: NCT06438172

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HCP1803-3
Description: Take it once daily for 8 weeks orally.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RLD2001-1
Description: Take it once daily for 8 weeks orally.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: HPP2003-3
Description: Placebo drug. Take it once daily for 8 weeks orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HPP2002-1
Description: Placebo drug. Take it once daily for 8 weeks orally.
Study: NCT05946408

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised antenatal exercises
Description: Supervised antenatal exercises along with education twice a week. Protocol consists of warm up (10 min), Aerobic training (20 mins, 60-75% of max. HR), Strength training (25 minutes), followed by a cool down of 15 minutes.~The Interventions to be provided for a period of 12 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Antenatal Education
Description: Antenatal education at 12th week of pregnancy. Which consists of education on Posture in pregnancy, Role of pelvic floor muscles, Labor and breathing and relaxation techniques.
Study: NCT06287320

Intervention type: RADIATION
Intervention: concurrent or sequential chemoradiotherapy
Description: Thoracic radiation therapy(with the prescribed dose of 50-70 Gy), concurrently or sequentially combined with platinum-based doublet chemotherapy.

Intervention type: RADIATION
Intervention: concurrent or sequential chemoradiotherapy
Description: Thoracic radiation therapy(with the prescribed dose of 50-70 Gy), concurrently or sequentially combined with platinum-based doublet chemotherapy.

Intervention type: DRUG
Intervention: Immunotherapy
Description: anti-PD-1/anti-PD-L1 immune checkpoint inhibitors
Study: NCT04332588

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]FMISO PET/MRI imaging
Description: \[18F\]FMISO PET/MRI imaging

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]FMISO PET/MRI imaging
Description: \[18F\]FMISO PET/MRI imaging
Study: NCT04989855

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib plus Tislelizumab
Description: 2 cycles of Fruquintinib(F) 5mg QD d1-d14 + Tislelizumab(T) 200mg IV d1, Q3W as preoperative therapy, and F +T after TME as postoperative therapy for 6 months
Study: NCT05417854

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Splenic Ultrasound
Description: Daily ultrasound application to the spleen of approximately 18 minutes per day, 5 days per week for up to 8 weeks, in addition to standard clinical care.
Study: NCT06319105

Intervention type: OTHER
Intervention: Standard intervention: Offer PrEP choice
Description: This hybrid observational-implementation study will observe the implementation of a choice of oral pre-exposure prophylaxis or long-acting injectable cabotegravir for pre-exposure prophylaxis for all participants.
Study: NCT06194773

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Totalfil
Description: Root canal treatment using TotalFil sealer

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: NeoSealer
Description: Root canal treatment using NeoSealer

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: AH-Plus sealer
Description: Root canal treatment using AH-Plus sealer
Study: NCT05934500

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol Oil
Description: Subjects will self administer CBD sublingually

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol Oil
Description: Subjects will self administer CBD sublingually
Study: NCT06370455

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: comparison of septal advancement flap effect on nasal tip in primary rhinoplasty to columellar strut technique
Description: All patients will be operated on under general anesthesia through an open rhinoplasty then will undergo 2 different procedures according to each group.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: comparison of septal advancement flap effect on nasal tip in primary rhinoplasty to columellar strut technique
Description: All patients will be operated on under general anesthesia through an open rhinoplasty then will undergo 2 different procedures according to each group.
Study: NCT04925895

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamic soft tissue mobilization
Description: Dynamic soft tissue mobilization will be given in the following sequence, In supine position with 90˚ flexion of knee and hip joint deep longitudinal strokes will be applied from distal to proximal direction along with the tightened area of hamstring while passively stretching the hamstring. Total 5 longitudinal strokes will be applied followed by shaking for 20 seconds. Then progressed to the next dynamic technique in the above-mentioned sequence but the patient will be asked to do leg extension actively to achieve reciprocal inhibition of the hamstring muscle. In The next step, the subject will apply a force to the therapist's hand to engage the hamstring eccentrically as the muscle will be lengthened to its end range. In that position, the therapist will apply 5 deep longitudinal strokes from the distal towards the proximal direction on tight hamstring muscles.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Proprioceptive neuromuscular facilitation stretching
Description: The position of the patient will be supine lying with 90⁰ flexion of hip. Therapist will passively extend the knee joint where patient will feel a mild stretch. Then therapist will ask the patient to do knee flexion in counter resistance applied by the therapist by using about 50% of his maximum strength and isometric contraction of hamstring muscles will be achieved. Patient will maintain that isometric contraction for 8 seconds then relax on therapist command. Just after relaxation therapist will further stretch the hamstring muscle to the point of mild to moderate painless stretch and patient will hold it for 30 seconds. Three repetitions will be applied in each session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cryotherapy
Description: application of cold pack on knee joint for 10 minutes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cryotherapy
Description: application of cold pack on knee joint for 10 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Isometric knee strengthening excercises
Description: i. Isometric hip adductors exercises in crook lying: Two sets of 10 repetitions with a 10-seconds hold will be carried out.~ii. Isometric quadriceps strengthening exercises in supine lying: A towel roll underneath the knee joint will be used to perform this exercise. Two sets of 10 repetitions with a 10-seconds hold will be performed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isometric knee strengthening excercises
Description: i. Isometric hip adductors exercises in crook lying: Two sets of 10 repetitions with a 10-seconds hold will be carried out.~ii. Isometric quadriceps strengthening exercises in supine lying: A towel roll underneath the knee joint will be used to perform this exercise. Two sets of 10 repetitions with a 10-seconds hold will be performed.
Study: NCT05779826

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Play dough
Description: In the play dough group, play dough was used during the treatment of children receiving nebulizer therapy.
Study: NCT05275062

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IM92 CAR-T cells
Description: 2.5×10\^8 CAR-T cells
Study: NCT06430281

Intervention type: OTHER
Intervention: Manual therapy
Description: A manual force will be applied to a manikin positioned on a chiropractic treatment table. The force exerted during the manual therapy must align with the trial label indicated on the Manual Therapy Force Perception \[MTFP\] scale.
Study: NCT05480813

Intervention type: DEVICE
Group type: OTHER
Intervention: Automated KINCISE™ impaction system versus handheld traditional mallet
Description: The KINCISE™ Surgical Automated System (KINCISE) (DePuy Synthes Products, Inc, Warsaw, IN) was developed to replace the handheld mallet traditionally used in total hip arthroplasty (THA). The device is an FDA-approved medical instrument.

Intervention type: OTHER
Group type: OTHER
Intervention: Efficiency and ergonomics analysis and physical assessments
Description: Operational efficiency, ergonomic impaction, cognitive/physical/stress level evaluations,
Study: NCT05452278

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product A
Description: Tobacco-free pouch, 14 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product A
Description: Tobacco-free pouch, 14 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product A
Description: Tobacco-free pouch, 14 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product A
Description: Tobacco-free pouch, 14 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product B
Description: Tobacco-free pouch, 16 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product B
Description: Tobacco-free pouch, 16 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product B
Description: Tobacco-free pouch, 16 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product B
Description: Tobacco-free pouch, 16 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product C
Description: Tobacco-free pouch, 20 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product C
Description: Tobacco-free pouch, 20 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product C
Description: Tobacco-free pouch, 20 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product C
Description: Tobacco-free pouch, 20 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product D
Description: Tobacco pouch, 16.6 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product D
Description: Tobacco pouch, 16.6 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product D
Description: Tobacco pouch, 16.6 mg nicotine/pouch, used for 20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product D
Description: Tobacco pouch, 16.6 mg nicotine/pouch, used for 20 minutes
Study: NCT06420973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48+carboplatin±bevacizumab
Description: RC48 (2.5mg/kg iv on d1 , every 21d for 6 cycles) + Carboplatin (AUC5 iv on d1 every 21d for 6 cycles)±Bevacizumab (7.5-15mg/kg iv on d1 every 21d for 6 cycles) for treatment followed by RC48 (2.5mg/kg iv on d1 , every 21d for 8 cycles)±Bevacizumab (7.5-15mg/kg iv on d1 every 21d for progress ) maintenance therapy.
Study: NCT05393609

Intervention type: PROCEDURE
Intervention: Sigmoidectomy
Description: Conventional laparoscopic resection of the sigmoid colon

Intervention type: DIETARY_SUPPLEMENT
Intervention: Conservative
Description: According to current practice including advice on supplementary dietary fiber, analgetics, or laxatives when indicated.
Study: NCT06539572

Intervention type: PROCEDURE
Intervention: Cleft lip repair; palatoplasty; alveolar bone grafting
Description: cleft surgical treatment based on Chang Gung Craniofacial Center Protocol for cleft treatment
Study: NCT05769179

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage group
Description: Massage group will be applied classic massage and cervical stabilisation exercises 3 days a week for 4 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Connective tissue massage group
Description: Connective tissue massage group will be applied connective tissue massage and cervical stabilisation exercises 3 days a week for 4 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobilization group
Description: Mobilization group will be applied cervical mobilization techniques and cervical stabilisation exercises 3 days a week for 4 weeks
Study: NCT05416294

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Primary Relief
Description: The group will receive PENS treatment using Primary Relief in addition to the multimodal analgesia (morphine, ketorolac, methyl, prednisolone, adrenaline) including the periarticular infiltration of local anaesthetic and/or femoral or epidural catheter for postoperative pain management (bupivacaine, ropivacaine).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Inactive Primary Relief
Description: The group will receive a sham device with multimodal analgesia (morphine, ketorolac, methyl, prednisolone, adrenaline), including the periarticular infiltration of local anaesthetic and/or femoral or epidural catheter for postoperative pain management (bupivacaine, ropivacaine).
Study: NCT05108987

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Morning
Description: Exercise at moderate to hard intensity will be performed in the morning for up to 10 sessions for about 1 hour under supervision in the morning.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Afternoon
Description: Exercise at moderate to hard intensity will be performed in the morning for up to 10 sessions for about 1 hour under supervision in the afternoon.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Afternoon
Description: Exercise at moderate to hard intensity will be performed in the morning for up to 10 sessions for about 1 hour under supervision in the afternoon.