TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06739174

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Confidence Be 1-Piece Closed Bag
Description: Active Chamber Filter - Circle Shape

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Confidence Natural 1-Piece Closed Bag
Description: Protective Filter - Circle Shape
Study: NCT05587998

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: Participants will receive IV dose of Morphine as stated in arm description.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Morphine
Description: Participants will receive IV dose of Morphine as stated in arm description.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD4041
Description: Participants will receive oral doses of AZD4041 as stated in arm description.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive oral doses of placebo as stated in arm description.
Study: NCT04906187

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Arm A : intraoperative ANI monitoring of nociception
Description: For the experimental group (arm A), the sufentanil doses are adjusted to maintain an ANI between 50 and 70. Morphine doses are adjusted from 0.05 to 0.05 µg / ml. Intraoperative data will be collected for ANI, TIVA and hemodynamics.

Intervention type: OTHER
Group type: OTHER
Intervention: Arm B : no specific monitoring of nociception
Description: For the control group (arm B), adjustments to the opioid doses are made in relation to the hemodynamic reactions of the patient and the operating times. Intraoperative data will be collected for TIVA and hemodynamics.
Study: NCT05459935

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PBM Tonsil Arm
Description: exposure of hypertrophic tonsils to photobiomodulation
Study: NCT06739174

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Confidence Be go 1-Piece Closed Bag
Description: Active Chamber Filter - Hexagon Shape
Study: NCT06741020

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab, Oxaliplatin, Fluorouracil,Leucovorin
Description: Chemotherapy drugs including Oxaliplatin, Fluorouracil,Leucovorin and immunotherapy durgs Adebrelimab will infuse to liver by transarterial catheter toward to the lesion.
Study: NCT05913245

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Maltodextrin 12.5%
Description: Preoperative Maltodextrin 12.5%

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Water
Description: Preoperative water
Study: NCT05726058

Intervention type: DEVICE
Group type: OTHER
Intervention: XyCAM with oxygen
Description: After the standard imaging protocols, participants will be asked to inhale 100% oxygen through a mask and will be re-imaged using the XyCAM RI or XyCAM FC.

Intervention type: DEVICE
Group type: OTHER
Intervention: XyCAM with oxygen
Description: After the standard imaging protocols, participants will be asked to inhale 100% oxygen through a mask and will be re-imaged using the XyCAM RI or XyCAM FC.
Study: NCT05459935

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham PBM Tonsil Arm
Description: non-powered exposure of hypertrophic tonsils to photobiomodulation
Study: NCT04284436

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treadmill walking
Description: Treadmill walking 4 days per week for 30 minutes in the target heart rate

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treadmill walking
Description: Treadmill walking 4 days per week for 30 minutes in the target heart rate
Study: NCT05726058

Intervention type: DEVICE
Group type: OTHER
Intervention: XyCAM with oxygen
Description: After the standard imaging protocols, participants will be asked to inhale 100% oxygen through a mask and will be re-imaged using the XyCAM RI or XyCAM FC.
Study: NCT06736665

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Orbital atherectomy
Description: The Diamondback-360 (OAS) (Abbott) device is used to perform this technique, consisting of a bidirectional, diamond-coated orbital crown that utilizes a combination of centrifugal force (creating elliptical orbits) and surface abrasion to modify the calcified plaque and increase distensibility. Additionally, the pulsatile impact of the crown at high speed can create microfractures in deep calcium. As a result, a single 1.25 mm crown can treat vessels ranging from 2.5 to 4 mm in diameter.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intravascular lithotripsy
Description: The Shockwave Medical Intravascular Lithotripsy System (Shockwave Medical) is a balloon that emits pulsatile sonic waves capable of fracturing intracoronary calcium. This therapy is administered by advancing a catheter and inflating the balloon at low pressure to deliver sonic pulses.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Optical Coherence Tomography (OCT)
Description: Optical Coherence Tomography (OCT) is an intravascular imaging modality that uses near-infrared light to provide high-definition, cross-sectional and three-dimensional images of the vessel microstructure.~These images provide additional information on the degree and characteristics of coronary artery disease compared to angiography which doesn't delineate the composition of the coronary artery. With automated, highly accurate measurements, OCT can guide stent selection, placement, and deployment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Optical Coherence Tomography (OCT)
Description: Optical Coherence Tomography (OCT) is an intravascular imaging modality that uses near-infrared light to provide high-definition, cross-sectional and three-dimensional images of the vessel microstructure.~These images provide additional information on the degree and characteristics of coronary artery disease compared to angiography which doesn't delineate the composition of the coronary artery. With automated, highly accurate measurements, OCT can guide stent selection, placement, and deployment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous coronary intervention with stent implantation
Description: All patients will undergo percutaneous coronary intervention with drug-eluting stent implantation after plaque modification using the technique assigned by randomization.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous coronary intervention with stent implantation
Description: All patients will undergo percutaneous coronary intervention with drug-eluting stent implantation after plaque modification using the technique assigned by randomization.
Study: NCT06739447

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Consumer Wearable Device Vital Sign Measurement
Description: Consumer Wearable Devices such as the Fitbit, are durable devices that can provide vital sign data.
Study: NCT06738186

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video-based exercise program
Description: The video-based exercise program - Bliib fit -mach mit! focuses on mobilization, muscle strengthening (focus on lower and upper extremities), coordination, balance, and relaxation. Each participant requires the use of a chair for support and to perform exercises in a seated position, if required. The group sessions are supervised by a care professional or registered activation specialist of the residential care facility.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Caregiver-led activation program
Description: The caregiver-led activation program (DESKK- Demenzspezifisches Kurzzeitpflegekonzept) is instructed and carried out by care professionals (e.g., nursing staff) as optimized standard care conducted individually or in groups.
Study: NCT06739135

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Visual feedback training
Description: Visual feedback training to modify use of the accelerator pedal when driving in a driving simulator, to reduce the % of time driving with the pedal pushed down more than 9 degrees
Study: NCT06739317

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation
Description: Subjects receive Stereotactic Body Radiotherapy combined with Camrelizumab and Apatinib as conversion therapy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: First line therapy
Description: Subjects receive Camrelizumab intravenously. Subjects receive Apatinib orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: First line therapy
Description: Subjects receive Camrelizumab intravenously. Subjects receive Apatinib orally.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: operation
Description: If subjects suitable for hepatic resection after conversion therapy, radical surgery and postoperative adjuvant therapy will be performed.
Study: NCT06740292

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: conventional miniplates
Description: conventional miniplates in double configuration

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: InterFlex plates
Description: InterFlex plates in configuration
Study: NCT06736847

Intervention type: PROCEDURE
Intervention: distal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision (CME) in gastric cancer
Description: distal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision (CME) in gastric cancer
Study: NCT06738212

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group A aerobic exercises
Description: Group A will perform the aerobic exercises (such as bicycling, treadmill and running) Aerobic exercises 15min/session for each exercise, 2 times/week. Frequency: 2 times /week Intensity: Easy to moderate about 60 to 75% of maximum heart rate Type: treadmill, bicycling, running Time: 45min/session~Bicycling:~15~- Start with gentle, low-intensity cycling and gradually increase as comfort allows - Aim for regular, consistent cycling sessions (e.g., 2-3 times a week,15min/session) - Consider incorporating other exercises, like stretching or yoga, to complement cycling.~Running~To get started with running for dysmenorrhea:~1. Start with short distances and gradually increase as comfort allows~2. Aim for regular, consistent running sessions (e.g., 2-3 times a week,15 minute/session)~3. Consider incorporating other exercises, like stretching or yoga, to complement running.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group B Aviva exercises
Description: Group B will perform the Aviva exercises in 18 different movements. Aviva exercise intervention method is based on a carefully structured, mild-to-moderate intensity series of 18 movement sequences and aerobic exercises 30min/session, 2 times/week (20)~Aviva Methods of exercises:~These exercises are a carefully structured, intense, and methodical series of movement sequences, including a 5 min warm-up exercise at the beginning and 5 min cooling-down exercises at the end of the session. These exercises are performed in Standing, Sitting, Supine lying, prone lying
Study: NCT06741293

Intervention type: OTHER
Intervention: No intervention: observational study
Description: No intervention: observational study

Intervention type: OTHER
Intervention: No intervention: observational study
Description: No intervention: observational study

Intervention type: OTHER
Intervention: No intervention: observational study
Description: No intervention: observational study

Intervention type: OTHER
Intervention: No intervention: observational study
Description: No intervention: observational study
Study: NCT06739148

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Level Laser Therapy
Description: Low-level laser therapy can increase cellular energy production, making it useful as a pre-conditioning treatment to prevent muscle contraction fatigue or as a post-contraction therapy to accelerate fatigue recovery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: blood flow restriction
Description: Its advantage is that during training, it can surpass the \&#34;overload principle,\&#34; allowing for effective muscle cross-sectional area growth with relatively light weight training (20%-50% of 1RM or 20%-40% of MVC).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: blood flow restriction
Description: Its advantage is that during training, it can surpass the \&#34;overload principle,\&#34; allowing for effective muscle cross-sectional area growth with relatively light weight training (20%-50% of 1RM or 20%-40% of MVC).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neuromuscular Electrical Stimulation
Description: It is a strength training method that uses electrical currents to stimulate nerve and muscle activation, helping to maintain muscle mass, increase blood flow, and slow down or prevent muscle atrophy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neuromuscular Electrical Stimulation
Description: It is a strength training method that uses electrical currents to stimulate nerve and muscle activation, helping to maintain muscle mass, increase blood flow, and slow down or prevent muscle atrophy.
Study: NCT06486805

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: N acetyl cysteine
Description: N-acetylcysteine (NAC) is a small molecule containing a thiol (sulfhydryl-containing) group, which has antioxidant properties and is freely filterable, thus making it readily accessible to the intracellular compartment
Study: NCT05979012

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MIndfulness Listening to Jazz
Description: All groups will complete a baseline and 4-week follow-up survey.~Participants in Jazz Group 1 and Jazz Group 2 will engage in daily listening 4-week intervention.It is up to them if they want to listen to the daily recordings.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Listening to Jazz
Description: All groups will complete a baseline and 4-week follow-up survey.~Participants in Jazz Group 1 and Jazz Group 2 will engage in daily listening 4-week intervention.They will have access to electronic audio recordings, with the order of listening labeled for each day. The recordings will increase gradually throughout the study, starting with about 10 minutes each day in the first week and reaching 30 minutes each day in the final week. The schedule is as follows: Week 1= 10 minutes, Week 2= 15 minutes, Week 3= 20 minutes Week 4= 30 minutes. It is up to them if they want to listen to the daily recordings.
Study: NCT05730608

Intervention type: OTHER
Group type: OTHER
Intervention: 18F-FDG PET/CT
Description: Included breast cancer patients will undergo a 18F-FDG PET/CT scan in addition to conventional imaging with CT and bone scintigraphy.

Intervention type: OTHER
Group type: OTHER
Intervention: 18F-FDG PET/CT
Description: Included breast cancer patients will undergo a 18F-FDG PET/CT scan in addition to conventional imaging with CT and bone scintigraphy.
Study: NCT05888714

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental FES cycling
Description: Using the experimental, new FES cycling device, provide neuromuscular electrical stimulation of the gluteal, quadriceps and hamstring muscles at sufficient intensity to cause muscle contraction and push the cycle ergometer pedals for 30 minutes, for 16 treatment sessions (twice a week, for 8 weeks), in addition to conventional physical therapy for muscle strengthening.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Comparator FES cycling
Description: Using the comparator, marketed FES cycling device, provide neuromuscular electrical stimulation of the gluteal, quadriceps and hamstring muscles at sufficient intensity to cause muscle contraction and push the cycle ergometer pedals for 30 minutes, for 16 treatment sessions (twice a week, for 8 weeks), in addition to conventional physical therapy for muscle strengthening.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Conventional physical therapy for muscle strengthening, for 16 treatment sessions (twice a week, for 8 weeks).
Study: NCT05102201

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Paro (social robot) intervention
Description: Participants in the Paro group will receive a group (6-8 people as a group), facilitated, and 30-minute weekly session Paro intervention for 6 weeks
Study: NCT05196698

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Flow Oxygen Therapy
Description: HFOT will be delivered validated medical devices and established as follow:~* Patient will be acclimatized to HFOT which will aim to achieve a flow of air of 30L/min at a temperature of 34°C using dedicated nasal canula.~* Once patient acclimatized, oxygen will be entrained in the HFOT device at a flow that will aim to achieve a saturation \> 90%. An arterial blood gas will be performed with such oxygen delivery, flowrate and temperature to ensure a PaO2 ≥ 8kPa

Intervention type: OTHER
Group type: OTHER
Intervention: Long-term oxygen therapy
Description: LTOT delivery will be performed according to French guidelines
Study: NCT06083467

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Brain MRI Scan
Description: MRI scan of the brain

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Neurologic exam
Description: Neurologic exam and assessments, including video interview
Study: NCT05086068

Intervention type: DEVICE
Group type: OTHER
Intervention: Arthrosamid
Description: Intra-articular hydrogel injection comprising of water and cross-linked polyacrylamide.
Study: NCT05455762

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The intervention consists of 8 week of combined resistance and aerobic exercise. Patients will exercise 6 days a week;3 days aerobic ones and 3 days resistance ones. The aerobic exercise include 20 minutes of walking divided into three parts. In the first five minute the patients walks slowly to warm up, in the next 10 minutes the patient will speedup to reach the intensity described by the physiotherapist. In the last 5 minutes the patient walks like the first five minutes. The middle 10 minutes may be increased or not based on patient's weekly report. The resistance training consists of 5 exercise; hip abduction, shoulder abduction, bridging, elbow flexion and knee extension. each of these exercises is done in 3 set of 10 repetition with one minute break between each set. Based on patients' weekly report a 0.5 kilogram weight might be added.
Study: NCT04735575

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: EMB-06
Description: EMB-06 is a FIT-Ig® bispecific antibody against BCMA and CD3.
Study: NCT06329089

Intervention type: PROCEDURE
Intervention: Reoperative Sentinel Lymph Node Biopsy
Description: Reoperative sentinel lymph node biopsy refers to a surgical procedure performed when there is a need to re-examine the sentinel lymph nodes (SLNs) in patients who have previously undergone breast cancer surgery. The sentinel lymph nodes are the first lymph nodes to which cancer cells are likely to spread from the primary tumor. During the procedure, the surgeon locates and removes the previously identified sentinel lymph nodes using techniques such as lymphatic mapping and injection of a radiotracer or dye. The removed lymph nodes are then examined by a pathologist to determine if there is any evidence of cancer spread.
Study: NCT06486805

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: the same volume of normal saline
Study: NCT04910087

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Sonographic optic nerve sheath diameter measurement
Description: With the linear ultrasound probe operating at 11 MHz in B mode, it will be measured in 2 planes, 3.0 mm behind the optic disc, the transverse plane where the probe is placed horizontally and the sagittal plane where the probe is placed vertically. Then, the average of these measurements will be recorded for both eyes every 10 minutes.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Sonographic optic nerve sheath diameter measurement
Description: With the linear ultrasound probe operating at 11 MHz in B mode, it will be measured in 2 planes, 3.0 mm behind the optic disc, the transverse plane where the probe is placed horizontally and the sagittal plane where the probe is placed vertically. Then, the average of these measurements will be recorded for both eyes every 10 minutes.
Study: NCT06512220

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin 25 mg
Description: The psilocybin used in this study meets quality specifications suitable for human research use. The active drug is encapsulated using a hydroxypropyl methylcellulose (HPMC) capsule and contains 25 mg of psilocybin. The psilocybin will be administered once during the trial in combination with or without risperidone 1 mg. It will also be administered in conjunction with supportive therapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin 25 mg
Description: The psilocybin used in this study meets quality specifications suitable for human research use. The active drug is encapsulated using a hydroxypropyl methylcellulose (HPMC) capsule and contains 25 mg of psilocybin. The psilocybin will be administered once during the trial in combination with or without risperidone 1 mg. It will also be administered in conjunction with supportive therapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risperidone 1 MG
Description: The risperidone is encapsulated using a cellulose capsule and contains 1 mg of risperidone. The risperidone will be administered once during the trial in combination with psilocybin 25 mg. It will also be administered with supportive therapy.
Study: NCT04889898

Intervention type: DEVICE
Intervention: Digital recording of speech and swallow sounds using the Beiwe Digital Health App on a personal smartphone
Description: \[Patients only\] Weekly completion of audio recordings of speech and swallowing performed at home by the subject using the study smartphone application on their personal device.

Intervention type: RADIATION
Intervention: Modified Barium Swallow Study (MBSS)
Description: \[Patients only\] MBSS is an instrumented evaluation of oropharyngeal swallowing function that is performed using videofluoroscopy.

Intervention type: BEHAVIORAL
Intervention: Speech Intelligibility Test (SIT)
Description: \[Patients only\] The SIT is a standardized test for measuring speech intelligibility.
Study: NCT05763862

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genetic testing
Description: Same information as details in the experimental arm.
Study: NCT05633355

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rocatinlimab
Description: Subcutaneous (SC) injection
Study: NCT04889898

Intervention type: BEHAVIORAL
Intervention: SIT Scoring
Description: \[Listeners only\] Listeners will judge the intelligibility of speech recordings made by patients in the study.