TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05898217

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dairy Milk
Description: Daily, each participant will consume 16 oz of the type of milk (plant based or dairy) two which they are randomized.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Soy Milk
Description: Daily, each participant will consume 16 oz of the type of milk (plant based or dairy) two which they are randomized.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Almond Milk
Description: Daily, each participant will consume 16 oz of the type of milk (plant based or dairy) two which they are randomized.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oat Milk
Description: Daily, each participant will consume 16 oz of the type of milk (plant based or dairy) two which they are randomized.
Study: NCT04840082

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Nasopharyngeal swab for COVID-19 testing
Description: A nasopharyngeal swab was performed endoscopically video guided to measure the actual length from to the mid turbinate and the posterior nasopharyngeal wall
Study: NCT05513339

Intervention type: DEVICE
Intervention: WHOOP strap 4.0
Description: Subjects will wear the WHOOP strap 4.0 for continuous physiologic monitoring.
Study: NCT05154110

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stretching on whole body vibration
Description: SSubjects will be refrained from maximum-effort or new routines for exercise the day before each treatment.Static stretching of hamstring on whole body vibration will include Pre- and post-test active and passive ROM for the both legs, with subjects first undergoing a 5-minute warm-up on a stationary bicycle. The traditional static stretch consisted of a supine active knee extension on whole body vibration (WBV) at 30 Hz at the high amplitude setting will be performed. The stretch will be held at the point of the onset of discomfort 3 times each for 30 seconds, with a 20-second rest period between each stretch. Participants will stretch for 4 days per week for 4 weeks. Active hamstring ROM will be measured via active knee extension using a goniometer with the leg in 90° of hip flexion, with the opposite leg extended. Passive ROM will be measured via clinician-assist ted knee extension with the leg in 90° of hip flexion.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strength training
Description: In second group, strength training will be done for 4 days per week for 4 days. Subjects will have 5 minutes warm up. In 1st week, the protocol will be Nordic hamstring curl (NHC) with bend (3 sets of 8 reps), Prone hamstrings curl (4 sets of 12 reps/leg), Physio-ball leg curl (3 sets of 8 reps), Glute bridge (2 sets of 50 s/leg). In 2nd to 4th week, the protocol will be NHC with bend (3 sets of 12 reps) Prone hamstrings curl (3 sets of 14 reps/leg) Physio-ball leg curl (3 sets of 10 reps) Glute bridge (2 sets of 50 s/leg). There will be 30 seconds rest between each set and 1 minute rest between each exercise . Pre and post AROM and PROM will be measured. Active hamstring ROM will be measured via active knee extension using a goniometer with the leg in 90° of hip flexion, with the opposite leg extended. Passive ROM will be measured via clinician-assisted knee extension with the leg in 90° of hip flexion.
Study: NCT05665010

Intervention type: OTHER
Intervention: Genetic susceptibility
Description: Genetic susceptibility increases the risk of ovarian injury

Intervention type: OTHER
Intervention: Genetic susceptibility
Description: Genetic susceptibility increases the risk of ovarian injury
Study: NCT05491408

Intervention type: DEVICE
Intervention: Cough assist device
Description: A device that facilitates airway secretion clearance in COPD patients, thus avoiding hospitalisations and preventing pneumonias and episodes of respiratory failure \[4,5\].
Study: NCT06518044

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N Acetyl L Cysteine
Description: For subjects in the experimental intervention arm (NAC group), if the patients met the inclusion criteria on day 14 before conditioning, they received NAC from day 14 before conditioning until day +60 post-HSCT. The initial dose of NAC was 400mg orally three times daily (TID). In cases of grade 3 or worse AEs (not including hematologic recovery), dose modifications including dose reductions or interruptions were permitted at the physician's discretion. After the resolution of AEs, the dose was re-escalated from to 400mg TID.
Study: NCT05067517

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nintedanib
Description: Randomized in a 1:1 ratio to either oral nintedanib 150 mg (n=80) or matching placebo (n=80) twice daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Randomized in a 1:1 ratio to either oral nintedanib 150 mg (n=80) or matching placebo (n=80) twice daily.
Study: NCT04899622

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MBSR
Description: Participants will attend weekly online classes (two hours duration) of MBSR for eight weeks. The classes will be delivered live online to groups of up to fifteen participants and will be led by Mindfulness instructors with MSc degrees in Mindfulness Based Interventions. The programme content will be based on the standard MBSR programme and is tailored towards key concerns and difficulties experienced by individuals with chronic pain.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants will attend weekly classes of supervised classes (1 hour) for eight weeks, following the MBSR class. The exercise class will be delivered live online to the group by an experienced Physiotherapist and will consist of a range of flexibility and strengthening exercises which will be advanced every two weeks for the duration of the eight week programme. The exercises will also be available in video format on the mobile application Physitrack which each participant will be invited to download. This will allow the participants to review the exercises between sessions, record online if they have completed each exercise and in addition rate their pain experience while completing the exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online Self-Management Guide
Description: Participants will receive standard evidence based self-guided information which they will access independently via the members area of the study website. This 'Online Self-Management Guide' will consist of eight categories of self-management; (1) What is chronic pain? (2) Chronic pain and nutrition (3) Sleep issues with chronic pain (4) Activity and exercise (5) Pacing (6) Using a pain diary (7) Relaxation and mindfulness and (8) Course summary. The information will be presented in the form of general text, links to online resources and videos. The information in this area will be updated biweekly during the eight week programme with the participants receiving bi-weekly email reminders.
Study: NCT05220878

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GNR-069
Description: Once a week as a subcutaneous injection. The initial dose is 1 mcg/kg.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Nplate
Description: Once a week as a subcutaneous injection. The initial dose is 1 mcg/kg.
Study: NCT06424132

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rewarming Exposure Period
Description: Following cold exposure, the cold vests will be removed, and participants will be offered a warm blanket to ease the transition from cold back to warm temperatures. Participants will then be moved to an adjacent warm room maintained at 30 degrees celsius and asked to return to the resting position of their choice. Participants will then engage in reading and/or digital entertainment for a 3-hour warm exposure period.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rewarming Exposure Period
Description: Following cold exposure, the cold vests will be removed, and participants will be offered a warm blanket to ease the transition from cold back to warm temperatures. Participants will then be moved to an adjacent warm room maintained at 30 degrees celsius and asked to return to the resting position of their choice. Participants will then engage in reading and/or digital entertainment for a 3-hour warm exposure period.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting
Description: Participants will be requested to refrain from food and caloric drinks for 12 hours (starting at 8pm) prior to the study visit. Blood will then be drawn the following morning (between 8 and 9am) 30mins later following a breakfast meal (9:30am- 10am). Participants will be housed in a room with ambient temperature at 25 degrees celsius between the two blood draws.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting
Description: Participants will be requested to refrain from food and caloric drinks for 12 hours (starting at 8pm) prior to the study visit. Blood will then be drawn the following morning (between 8 and 9am) 30mins later following a breakfast meal (9:30am- 10am). Participants will be housed in a room with ambient temperature at 25 degrees celsius between the two blood draws.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting
Description: Participants will be requested to refrain from food and caloric drinks for 12 hours (starting at 8pm) prior to the study visit. Blood will then be drawn the following morning (between 8 and 9am) 30mins later following a breakfast meal (9:30am- 10am). Participants will be housed in a room with ambient temperature at 25 degrees celsius between the two blood draws.
Study: NCT04809571

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Photoacoustic imaging and Confocal Raman spectroscopy measurement
Description: All subjects will first have their basic history and clinical measurements taken, followed by skin physiology measurements and photoacoustic mesoscopic imaging as well as confocal Raman spectroscopy measurements.
Study: NCT05583123

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: restored abutment (OPZAs)
Description: The restorations will be restored by the OPZAs

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: restored abutment (TPZAs)
Description: The restorations will be restored with the TPZAs with friction-fitted titanium bases.
Study: NCT03061435

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Screening anal Pap smear - No high-resolution anoscopy
Description: 75% of patients with negative cytology on their anal Pap smear will not receive high-resolution anoscopy

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Screening anal Pap smear - High-resolution anoscopy
Description: 25% of patients with negative cytology on their anal Pap smear will receive high-resolution anoscopy. All patients with positive (abnormal) cytology on their anal Pap smear will receive high-resolution anoscopy.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Screening anal Pap smear - High-resolution anoscopy
Description: 25% of patients with negative cytology on their anal Pap smear will receive high-resolution anoscopy. All patients with positive (abnormal) cytology on their anal Pap smear will receive high-resolution anoscopy.
Study: NCT06135428

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education Group
Description: Training content was prepared in three stages according to the resilience model in midwives. The training will be in the form of 45-minute presentations and sharings, and individual studies will be carried out in the form of homework according to people's methods of coping with stress. These homework assignments may occasionally include more or less individual meetings depending on the person's coping situation. However, at least 3 meetings will be held. Training and interviews will be conducted by researchers. For this, at least one of the researchers will receive training including personal awareness and motivational interviews.
Study: NCT05420376

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Split Mesh
Description: TEP repair of inguinal hernias using either split or whole mesh

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Split Mesh
Description: TEP repair of inguinal hernias using either split or whole mesh
Study: NCT05022160

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: pudendal nerve block
Description: All patients in the study group will receive bilateral pudendal nerve block at the end of surgery, with help of landmark technique, using 0.5% bupivacaine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pudendal nerve block
Description: All patients in the study group will receive bilateral pudendal nerve block at the end of surgery, with help of landmark technique, using 0.5% bupivacaine
Study: NCT05703750

Intervention type: PROCEDURE
Intervention: TACE ± Systemic therapy
Description: TACE: cTACE (conventional TACE) or dTACE (drug-eluting beads TACE); Systemic therapy: PD-1/PD-L1 inhibitors, VEGF-TKI/bevacizumab, PD-1/PD-L1 inhibitors+VEGF-TKI/bevacizumab, radiotherapy or chemotherapy.

Intervention type: PROCEDURE
Intervention: TACE ± Systemic therapy
Description: TACE: cTACE (conventional TACE) or dTACE (drug-eluting beads TACE); Systemic therapy: PD-1/PD-L1 inhibitors, VEGF-TKI/bevacizumab, PD-1/PD-L1 inhibitors+VEGF-TKI/bevacizumab, radiotherapy or chemotherapy.
Study: NCT06264713

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Immersive Virtual Reality
Description: Patients wear a head-mounted-display and will be immersed in a virtual environment. The stimuli will be provided in the left, center and right visual fields. Eye-tracking biofeedback will be provided about the real-time performance during each exercise.
Study: NCT04585425

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Sleep hygiene advice
Description: Participants receive standard sleep hygiene advice.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep hygiene advice
Description: Participants receive standard sleep hygiene advice.
Study: NCT06264713

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sham Immersive Virtual Reality
Description: The patients performed the same protocol of the experimental group, differently to the immersive virtual reality group, from session 2 to session 8 (7 sessions), the stimuli will be provided in the center and right visual fields.
Study: NCT04585425

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bedtime music listening
Description: Participants in the intervention group listen to their preferred sleep playlist daily at bedtime for minimum 30 minutes.
Study: NCT06168695

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: removable anterior expansion screw
Description: For the upper and lower arches, precise and profound alginate impressions were obtained and plaster study models were created. The removable appliance was constructed using acrylic resin with bilateral occlusal coverage for posterior teeth. The removable appliance was inserted in the patient's mouth and the patient was recalled after 24 hours to check the appliance fit.~Patient was recalled every four weeks until the dental cross-bite was corrected.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Speech and language evaluation
Description: speech evaluation was done by a Phoniatrician and all children were subjected to the Protocol of speech evaluation before expansion screw appliance insertion and after complete correction of anterior crossbite using an articulation test, intelligibility test, and spectrographic analysis.~* Articulation test: Five speech sounds were chosen to be studied /s/, /s /, /z/, /z/, /∫ /. The consonants were tested in the initial, medial, and final word positions.~* Speech intelligibility test : The general intelligibility score was calculated using Speech intelligibility in context: 5 -point scale:~* Spectrographic analysis: Using the computerized speech lab, the child was seated in an upright position \& allowed to talk freely \& repeated syllables were said to him/her.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral Health Related Quality of Life (OHRQoL) Assessment
Description: The Child Perceptions Questionnaire (CPQ 8-10) in Brazilian version was used to gauge how the anterior cross bite affected the children's OHRQoL. It has twenty-five items total, broken down into four health domains (subscales): five questions each about oral symptoms (OS), five questions about functional limitations (FL), five questions about emotional wellbeing (EW), and ten questions about social well-being (SW). The responses never (0), once/twice (1), occasionally (2), often (3), and every day/almost every day (4) are provided for each question on an ordinal scale. The sum of the scores for all questions is used to calculate the scores for each subscale. The CPQ 8-10 was used to assess the OHRQoL before appliance insertion and after complete correction of anterior crossbite.
Study: NCT05480579

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Dose4 placebo of single IV injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBI311
Description: Dose2 IBI311 of single IV injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBI311
Description: Dose4 IBI311 of single IV injection

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Dose3 placebo of single IV injection

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Dose1 placebo of single IV injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBI311
Description: Dose1 IBI311 of single IV injection
Study: NCT05047900

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Rapid antigen testing kit
Description: COVID-19 Saliva Antigen Rapid Test Tigsun COVID-19 Speichel Antigen-Schnelltest

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Rapid antigen testing kit
Description: COVID-19 Saliva Antigen Rapid Test Tigsun COVID-19 Speichel Antigen-Schnelltest
Study: NCT05583916

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Same Day Discharge - Video-Assisted Thoracoscopic Surgery (VATS) Lung
Description: All patients will be scheduled to surgery at the start of the day and will be discharged within the same day as the procedure.
Study: NCT04257890

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral therapy
Description: The CBT focuses on cognitive restructuring to reduce the specific key maladaptive beliefs on Internet gaming suggested by King's model, and develop useful coping skills (self-regulation/control, emotion regulation, problem-solving coping) that are adapted from previous CBT for adolescent IGD. In addition, it provides training on relapse-prevention and maintenance techniques.
Study: NCT05266768

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI346
Description: IBI346 Antibody and IBI346 CAR-T cell injection
Study: NCT05480579

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBI311
Description: Dose 3 IBI311 of single IV injection

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Dose2 placebo of single IV injection
Study: NCT05745168

Intervention type: DIAGNOSTIC_TEST
Intervention: OraQuick
Description: The intervention is based on respondent-driven sampling approach. Each selected seed from hotspots and on social networks is provided with two types of coupons for HIVST kit at partner pharmacy: electronic coupons (e-coupons) consisting of a pictured unique anonymous QR code and identifier and the address of pharmacies; paper coupons consisting of similar information to e-coupon. The seeds will then distribute coupons to their networks physically, via social media, and smart phone applications. Each recruited participant will bring the coupon to be scanned at the pharmacies to receive a free access HIVST kit. There, trained community worker will do the study visit including information/consent, e-CRF filling and providing link to send the test results. These recruited individuals will be considered as wave 1 and will each receive 10 additional coupons to recruit new members in the networks. The next round of individuals recruited and enrolled will be considered as wave 2, and so on.
Study: NCT04257890

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive behavioral therapy
Description: The CBT focuses on cognitive restructuring to reduce the specific key maladaptive beliefs on Internet gaming suggested by King's model, and develop useful coping skills (self-regulation/control, emotion regulation, problem-solving coping) that are adapted from previous CBT for adolescent IGD. In addition, it provides training on relapse-prevention and maintenance techniques.
Study: NCT05676853

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegzilarginase
Description: Individualized disease management which includes severe protein restriction, essential amino acid supplementation and the ammonia scavengers when indicated
Study: NCT05548140

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Novel Motorized Spiral Enteroscopy
Description: This study involves performance of spiral enteroscopy in one arm and single balloon enteroscopy in the other arm in patients who satisfy inclusion criteria

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Novel Motorized Spiral Enteroscopy
Description: This study involves performance of spiral enteroscopy in one arm and single balloon enteroscopy in the other arm in patients who satisfy inclusion criteria
Study: NCT04257890

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education material about IGD
Description: Printed education material introducing IGD will be distributed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education material about IGD
Description: Printed education material introducing IGD will be distributed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education material about CBT
Description: Printed education material introducing CBT will be distributed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education material about CBT
Description: Printed education material introducing CBT will be distributed.
Study: NCT04800627

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pevonedistat
Description: Given IV
Study: NCT06190028

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Iridium A Gel
Description: IRIDIUM® A gel is a sterile, preservative free ophthalmic gel, containing Carbopol, amino acids, Echinacea and Aloe extract. IRIDIUM® A gel is indicated for the protection of the eye surface particularly at night, even in the presence of changes in histological continuity and blepharitic conditions, including those of an iatrogenic nature, following the use of hypotonic eye drops and of the preservatives contained therein.