TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04851301

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Virtual Reality
Description: Participants will be assigned to an immersive VR environment.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Active Virtual Reality
Description: Participants will be assigned to an immersive VR environment.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Active Virtual Reality
Description: Participants will be assigned to an immersive VR environment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: sham Virtual Reality
Description: Participants will be assigned to a sham VR environment without the immersive experience.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: sham Virtual Reality
Description: Participants will be assigned to a sham VR environment without the immersive experience.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: sham Virtual Reality
Description: Participants will be assigned to a sham VR environment without the immersive experience.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No Intervention
Description: Participants will experience tonic pain tolerance tests without exposure to any environments.

Intervention type: OTHER
Group type: OTHER
Intervention: No Intervention
Description: Participants will experience tonic pain tolerance tests without exposure to any environments.
Study: NCT04975568

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App and face-to-face physical therapy
Description: Patients will use an app with health tests, general information about the study, personalized HTEP based in McGill's Program after their evaluations, and several online materials related with healthcare and healthy habits linked to social media sites. During the app used they will have 6 face-to-face sessions in 6 people groups with a physical Therapist in a 3 months period
Study: NCT06566794

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine Tablet
Description: 0,5 x 100 mg tablet (50 mg caffeine).
Study: NCT04975568

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: App physical therapy
Description: Patients will use an app with health tests, general information about the study, personalized HTEP based in McGill's Program after their evaluations, and several online materials related with healthcare and healthy habits linked to social media sites.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App physical therapy
Description: Patients will use an app with health tests, general information about the study, personalized HTEP based in McGill's Program after their evaluations, and several online materials related with healthcare and healthy habits linked to social media sites.
Study: NCT06720038

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 0.5 mL of the high dose VAX-31
Description: 31 valent pneumococcal conjugate vaccine

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: 0.5 mL dose of PCV20
Description: 20 valent pneumococcal conjugate vaccine
Study: NCT06721455

Intervention type: OTHER
Intervention: blood sampling
Description: Discarded blood samples will be taken from routine clinical labs drawn during and after heart surgery.
Study: NCT06721273

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Iodine
Description: In intervention group women will take 150 µg daily (one tablet per day, Tavan Institute, Tehran, Iran) that will be 2 months before starting the new in vitro fertilization (IVF) cycle.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Women will take a placebo tablet daily (containing white wheat flour, which is similar to iodine table in terms of size, shape, and color, Tavan Institute, Tehran, Iran) 2 months before starting the new IVF cycle.
Study: NCT06721338

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical thrombectomy via blood flow reversal using BOBBY balloon guide catheter
Description: After 2 min. of mechanical thrombectomy (MT), the side port of a BOBBY balloon guide catheter will be flushed again with heparin and the balloon deflated. A follow up angiogram will be performed to determine whether to proceed with another MT pass using the same procedure or to stop if successful recanalization has been achieved. At the end of the procedure, multiple angiograms will be performed and used to record the final TICI score. Angiograms of neck vessels will be used to rule out complications. Groin angiograms will evaluate the puncture site before closure. The catheters will then be removed, allowing hemostasis to be achieved in the groin. An angioseal closure device will be used on the arterial site if not contraindicated and a venous Vascade for the venous side.
Study: NCT06721078

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Peer navigation effectiveness
Description: To determine the effectiveness of peer navigation on viral suppression and retention in care among adolescents living with HIV in South Africa.
Study: NCT06720571

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Auricular vagal neuromodulation therapy (aVNT)
Description: The aVNT device used in our study (Parasym ®) consists of a small portable unit connected to stimulation electrodes placed on the left ear. These electrodes deliver painless electrical microcurrents through the skin to stimulate the auricular branch of the vagus nerve (ABVN). The device parameters will be defined in accordance with the recommendations for use of the Parasym ® device and the pilot studies: frequency of 25 Hz, pulse width of 250 µS, and an intensity of 1 mA to 36 mA. Stimulation sessions will last for four hours each day, each of which can be divided into two sessions and conducted over a period of nine months. Patients will adjust the intensity at each session according to their comfort level, starting with a gradual increase until they feel a slight tingling sensation, followed by a decrease until discomfort disappears completely. Stimulation should take place during a relaxing activity but not should not take place during sleep, meals or major physical activity.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Auricular vagal neuromodulation therapy (aVNT)
Description: The sham stimulation control condition will be performed using the same aVNT Parasym® device under similar conditions (four hours a day, seven days a week, for nine months) but with a different location (without afferent vagus nerve fibers) or a control condition integrated into the device.
Study: NCT06720753

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Opposite to emotion action
Description: Participants will be taught the opposite action skill from Dialectical Behavior Therapy

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GIVE
Description: Participants will be taught the GIVE skill from Dialectical Behavior Therapy
Study: NCT06721910

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tocilizumab
Description: Blockade of the interleukin-6 receptor
Study: NCT06566794

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine Tablet
Description: 0,5 x 100 mg tablet (50 mg caffeine).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Caffeine Tablet
Description: 0,5 x 100 mg tablet (50 mg caffeine).
Study: NCT06721910

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Infusion of 100 ml normal saline
Study: NCT06719921

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: AF ablation
Description: The primary ablation strategy for both groups will be pulmonary vein isolation (PVI).~Other additional ablation, including but not limited to linear ablation, complex fractionated atrial electrogram (CFAE) ablation, or superior vena cava (SVC) isolation is not recommended unless necessitated by one of the following:~* Documented atrial flutter (AFL) or atrial tachycardia (AT) observed during the procedure, or~* Arrhythmias originating from the specific region requiring intervention.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: AF ablation
Description: The primary ablation strategy for both groups will be pulmonary vein isolation (PVI).~Other additional ablation, including but not limited to linear ablation, complex fractionated atrial electrogram (CFAE) ablation, or superior vena cava (SVC) isolation is not recommended unless necessitated by one of the following:~* Documented atrial flutter (AFL) or atrial tachycardia (AT) observed during the procedure, or~* Arrhythmias originating from the specific region requiring intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AF ablation in a non-fluoroscopic EP lab
Description: This procedure will take place in a non-fluoroscopic lab.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: AF ablation in a fluoroscopic lab
Description: This procedure will take place in a fluoroscopic lab.
Study: NCT06332391

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Exercise-similar cardiac pacing
Description: Cardiac pacing using subjects already-implanted cardioverter defibrillator to reproduced exercise heart rate envelope.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham cardiac pacing
Description: Simulated (rates selected using programmer but not initiated) cardiac pacing using subjects already-implanted cardioverter defibrillator to reproduced exercise heart rate envelope.
Study: NCT06721650

Intervention type: OTHER
Group type: OTHER
Intervention: Perturbation-Based Balance Training
Description: Perturbation-based balance training (PBT; or reactive balance training or perturbation training) is balance training that uses repeated, externally applied mechanical perturbations to trigger rapid reactions to regain postural stability in a safe and controlled environment

Intervention type: OTHER
Group type: OTHER
Intervention: the selected physical therapy exercise program
Description: trunk control therapeutic exercise, static and dynamic balance treaining exercises

Intervention type: OTHER
Group type: OTHER
Intervention: the selected physical therapy exercise program
Description: trunk control therapeutic exercise, static and dynamic balance treaining exercises
Study: NCT06721676

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcatheter aortic valve replacement in severe aortic stenosis
Description: transcatheter aortic valve replacement with A² Flex and commissural alignment technology in severe aortic stenosis
Study: NCT06719726

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PECS I Block
Description: The PECS I block is a regional anesthesia technique performed preoperatively under ultrasound guidance. It involves the injection of 10 mL of 0.5% bupivacaine between the pectoralis major and pectoralis minor muscles to block the medial and lateral pectoral nerves. This procedure targets the right breast in the study to reduce postoperative pain and is compared to local anesthetic infiltration.
Study: NCT05827224

Intervention type: DEVICE
Intervention: Lotrafilcon B spherical soft contact lenses
Description: Commercially available silicone hydrogel contact lenses

Intervention type: DEVICE
Intervention: Lotrafilcon B spherical soft contact lenses with comfort additive
Description: Commercially available silicone hydrogel contact lenses

Intervention type: DEVICE
Intervention: Lotrafilcon B toric soft contact lenses with comfort additive
Description: Commercially available silicone hydrogel contact lenses
Study: NCT06719726

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Local Anesthetic Infiltration
Description: Local anesthetic infiltration involves the intraoperative administration of 10 mL of 0.5% bupivacaine under direct visualization into the pectoralis major muscle and the edges of the dissected muscle. This procedure targets the left breast in the study for pain management and is compared to the PECS I block.
Study: NCT06721104

Intervention type: OTHER
Intervention: Dual Task
Description: The dual-task abilities of individuals will be assessed by adding motor and cognitive tasks to the 10-Meter Walk Test. The tasks given to participants are as follows:~Single Motor Task (comfortable walking): The individual is asked to walk at a normal pace, and the time is recorded.~Motor-Motor Dual Task: The individual carries a half-filled water bottle in each hand while walking, and the time is recorded.~Motor-Cognitive Dual Task (mental): The individual counts backward from 10 in increments of one while walking, and the time is recorded.~Motor-Cognitive Dual Task (memory): The individual is asked to recall three previously mentioned words while walking, and the time is recorded.
Study: NCT06563973

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk odor
Description: One hour before feeding time, 2 cc of breast milk was dripped onto a sterile sponge and placed inside the baby's incubator, close to the baby's nose (3 cm).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pacifier
Description: To support oral feeding, a pacifier was given for 3 minutes one hour before feeding time and for 2 minutes 10 minutes before feeding time.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pacifier
Description: To support oral feeding, a pacifier was given for 3 minutes one hour before feeding time and for 2 minutes 10 minutes before feeding time.
Study: NCT05319977

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile incentive-based intervention
Description: a technology-based behavioral intervention to address maternal alcohol use with mobile breathalyzer technology or/and urinalysis for biochemical verification of alcohol use, contingent financial incentives on alcohol abstinence, and text-based health promotion.
Study: NCT05072093

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PrEP discontinuation intervention
Description: Men taking daily oral PrEP (Truvada) will receive a monthly screener through the mobile app. If answers to screener questions indicate a participant is at risk for PrEP discontinuation, then a peer navigator will deliver a motivational interviewing intervention and a clinician will consult with the participant. These efforts are intended to avert PrEP discontinuation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Offering of on-demand oral PrEP
Description: For men who are not interested in daily oral PrEP or plan to discontinue daily oral PrEP, the investigators will offer on-demand oral PrEP (Truvada) which will allow them to take it immediately before/after a sexual encounter. It is hoped that this will serve as an alternative to daily oral PrEP use that is desirable for some people.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Offering of STI PEP
Description: All men in the cohort will be offered STI PEP (doxycycline) to use after condomless sex with the goal of averting STI diagnoses. At a dosage of 200 mg to be taken in a single dose ideally within 24 hours of possible exposure (e.g. condomless anal sex) and no later than 72 hours after exposure. Participants will be dispensed enough pills to allow for up to 3 weekly doses of 200mg doxycycline (i.e. 6 pills/week) for 3 months (the interval between STI testing visits).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Injectable PrEP
Description: For men who are interested in injectable PrEP, they will be referred to local providers to access Apretude (Cabotegravir injection) every two months. In the study, their use of the medication will be monitored through monthly surveys during which they have the option to indicate interest in switching to oral PrEP.
Study: NCT06538545

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sitting position is used in Experimental Arms 1-2
Description: sitting position Comparison of sitting position and lithotomy position in labor

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sitting position is used in Experimental Arms 1-2
Description: sitting position Comparison of sitting position and lithotomy position in labor

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sitting position is used in Experimental Arms 1-2
Description: sitting position Comparison of sitting position and lithotomy position in labor

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sitting position is used in Experimental Arms 1-2
Description: sitting position Comparison of sitting position and lithotomy position in labor
Study: NCT04851301

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: No Intervention
Description: Participants will experience tonic pain tolerance tests without exposure to any environments.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Naloxone
Description: 4mg of Naloxone will be administered (0.1 mL of 40 mg/ml naloxone solution given intranasally).~A random allocation sequence will be independently generated by the UM Pharmacy. The Principal investigator will call for each experiment.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Saline
Description: Intranasal Normal Saline (0.1 mL 0.9% sodium chloride) will be administered shortly before beginning the fMRI experiment.~A random allocation sequence will be independently generated by the UM Pharmacy. The Principal investigator will call for each experiment.

Intervention type: OTHER
Group type: OTHER
Intervention: Natural history
Description: Participants will not be provided Naloxone or Saline.
Study: NCT05827224

Intervention type: DEVICE
Intervention: Comfilcon A spherical soft contact lenses
Description: Commercially available silicone hydrogel contact lenses

Intervention type: DEVICE
Intervention: Comfilcon A toric soft contact lenses
Description: Commercially available silicone hydrogel contact lenses
Study: NCT05969353

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: accupunture
Description: BFA

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: accupunture
Description: BFA
Study: NCT05442359

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nano-bio fusion gingival gel
Description: Thin coat applied to cover the palate after free gingival graft harvest. A stent will be placed to retain its effect. Patients will receive the gel to be used at home twice daily till 3rd week and once in the 4th week

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: stent
Description: Applied as a palatal stent for palatal wound
Study: NCT04045600

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trad FCT
Description: This intervention emulates a traditional reinforcement schedule-thinning method during FCT in which clinicians program delays to reinforcement without discriminative stimuli (e.g., the child learns that some FCRs result in reinforcement and some do not). By programming reinforcement approximately every 15 s, the rate of reinforcement will be equivalent to mult FCT. During Period 1 of this project, trad FCT served as an appropriate control condition to which mult FCT could be compared.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trad FCT
Description: This intervention emulates a traditional reinforcement schedule-thinning method during FCT in which clinicians program delays to reinforcement without discriminative stimuli (e.g., the child learns that some FCRs result in reinforcement and some do not). By programming reinforcement approximately every 15 s, the rate of reinforcement will be equivalent to mult FCT. During Period 1 of this project, trad FCT served as an appropriate control condition to which mult FCT could be compared.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mult FCT
Description: This intervention involves correlating discriminative stimuli (e.g., purple and yellow index cards) with times in which reinforcement for the functional communication response (FCR) is and is not available. During Period 1 of this project, this procedure resulted in rapid reduction of destructive behavior and mitigated resurgence and renewal when the discriminative stimuli were used as programmed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mult FCT + Stimulus Fading
Description: This condition is similar to mult FCT except that the experimenters will gradually incorporate natural stimuli (e.g., rugs, tables, lamps) into sessions to approximate target settings that may occasion relapse typically without such gradual stimulus fading.
Study: NCT06361316

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan liposome injection
Description: Postoperative adjuvant therapy
Study: NCT06538233

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buffered articaine
Description: Injecting buffered articaine in maxillary anterior region and evaluate pain response.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Non buffered articaine
Description: Injecting non buffered articaine in maxillary anterior region and evaluate pain response.
Study: NCT06230744

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Lifestyle
Description: All participants will receive diet and exercise goals and coaching.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle II
Description: All participants will receive diet and exercise goals and coaching.
Study: NCT05669625

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational live attenuated varicella vaccine
Description: 0.5 ml/vial

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of live attenuated varicella vaccine
Description: 0.5 ml/vial
Study: NCT05882825

Intervention type: OTHER
Intervention: Dry Needling Therapy Knowledge and Awareness Questionnaire
Description: Dry Needling Therapy Knowledge and Awareness Questionnaire is a questionnaire consisting of a total of 14 questions created by the researchers who are specialized in the field. The correct answer to each question is one point. A high score indicates a high level of knowledge and awareness, while a low score indicates a low level of awareness and knowledge.
Study: NCT05120986

Intervention type: OTHER
Intervention: IND/GLY/MF
Description: Prospective observational cohort study. There is no treatment allocation. Patients will be invited to participate in the study when attending participating community pharmacies with a first prescription of IND/GLY/MF with sensor or IND/GLY/MF without sensor

Intervention type: OTHER
Intervention: IND/GLY/MF
Description: Prospective observational cohort study. There is no treatment allocation. Patients will be invited to participate in the study when attending participating community pharmacies with a first prescription of IND/GLY/MF with sensor or IND/GLY/MF without sensor
Study: NCT05707273

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Autologous Anti-CD19 CAR-expressing T Lymphocytes
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration and Biopsy
Description: Undergo bone marrow aspirate
Study: NCT05778214

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Interventional Robotic System
Description: Cerebral angiography was performed by using the interventional robotic system