TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04921865

Intervention type: DEVICE
Intervention: DPS VA-LCP® Clavicle Plate 2.7 System; DPS VA-LCP® Clavicle Hook Plate 2.7 System
Description: The DPS VA-LCP® Clavicle Plate 2.7 System is indicated for the fixation of clavicle bone fragments. The system consists of three plate types: lateral, shaft, and medial, each available in different sizes and materials (titanium alloy and stainless steel). Each plate is available in left and right.~The DPS VA-LCP® Clavicle Clavicle Hook Plate 2.7 System is indicated or the fixation of lateral clavicle fractures and AC joint dislocations. The Clavicle Hook Plate system consists of three plate types: long, short and button plates.
Study: NCT05642338

Intervention type: DIAGNOSTIC_TEST
Intervention: WATS3D
Description: the WATS3D brush samples the esophagus by abresing the tissue. the brush is directed through the workingchanel of endoscope into the oesophagus
Study: NCT03012243

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Gallbladder aspiration
Description: Percutaneous ultrasound-guided aspiration of bile from the gallbladder. This is performed without leaving a drain in the gallbladder. The aspiration is performed with the intention to relief the pressure in the gallbladder, without drain.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cholecystostomy
Description: Ultrasound-guided insertion of drain in the gallbladder. The drain is left in the gallbladder until clinical assessment and laboratory analyses show that the acute cholecystitis has been successfully treated.
Study: NCT06207513

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Suction Circuit Flushing with Chlorhexidine
Description: Patient intubated with an endotracheal tube and on a mechanical ventilator will receive endotracheal suctioning procedure using an open endotracheal suction catheter that is used multiple times during a 12-hour nursing shift. Flushing of the suctioning circuit will be performed with 40 ml of chlorhexidine gluconate 0.2% after every endotracheal suction procedure

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suction Circuit Flushing with Chlorhexidine
Description: Patient intubated with an endotracheal tube and on a mechanical ventilator will receive endotracheal suctioning procedure using an open endotracheal suction catheter that is used multiple times during a 12-hour nursing shift. Flushing of the suctioning circuit will be performed with 40 ml of chlorhexidine gluconate 0.2% after every endotracheal suction procedure

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suction Circuit Flushing with Chlorhexidine
Description: Patient intubated with an endotracheal tube and on a mechanical ventilator will receive endotracheal suctioning procedure using an open endotracheal suction catheter that is used multiple times during a 12-hour nursing shift. Flushing of the suctioning circuit will be performed with 40 ml of chlorhexidine gluconate 0.2% after every endotracheal suction procedure
Study: NCT06334861

Intervention type: BIOLOGICAL
Intervention: Herpes Zoster adjuvanted recombinant vaccine
Description: patients will receive two doses of vaccine with an interval between the first and second dose of 2 months
Study: NCT05721950

Intervention type: DRUG
Intervention: Brigatinib
Description: Brigatinib Tablets
Study: NCT05148078

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PROMISE (Pediatric Radiation Oncology with Movie Induced Sedation Effect)
Description: Pediatric Radiation Oncology with Movie Induced Sedation Effect (PROMISE) is an interactive, incentive-based movie system that integrates with a video surveillance gating module (VisionRT) to help keep a child's attention and prevent him or her from moving during radiation treatment. This technology is being studied as an alternative sedation solution for pediatric patients needing radiation treatment. As part of the trial, patients will be attempted to have CT simulation scan and first radiation treatment(s) using PROMISE, with general anesthesia on standby should PROMISE be unsuccessful. If PROMISE is unsuccessful for a given patient, then standard of care general anesthesia will be used for that patient's radiation treatment and PROMISE will be reattempted at physician discretion with anesthesia on standby.
Study: NCT05895760

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-component physical exercise online intervention
Description: A multicomponent exercise program was implemented consisting of a combined program of endurance, strength, coordination, balance, and flexibility exercises depending on the level of functional capacity.~Three types of physical exercise programs were designed according to the physical performance level of each participant. The first type of exercise program training was performed for frail adults with an SPPB score of 4 to 6, the second was for the pre-frail adults with an SPPB score of 7 to 9 and the third for robust adults with an SPPB of 10 to 12.
Study: NCT05079282

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-4685
Description: ONO-4685 is administered by IV infusion. The administration of ONO-4685 will be continued until disease progression or unacceptable toxicity is observed
Study: NCT04998045

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Screening and brief intervention for substance use
Description: Screening will be done using the WHO Alcohol Smoking and Substance Involvement Screening Test (ASSIST). The brief intervention will be delivered based on ASSIST risk scores: low risk - verbal positive reinforcement and brief advice on harmful consequences of substance use (ii) moderate risk - brief motivational interviewing (BMI) (iii) high risk - BMI and referral to child psychiatry out-patient clinic. The BMI will be delivered in a single session (approximately 15 minutes) using Feedback Listen Options model (15): (i) providing feedback on screening results (ii) exploring pros and cons of substance use, enquiring about importance of change (iii) exploring options for change.
Study: NCT05912959

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: photo biostimulation
Description: the intervention is a type of wavelength around 820 nm. this method of treatment is totally safe. yet, it has many therapeutic effects on the cellular level as well as tissue and organ level. during treatment with laser, the patient does not feel any specific sensation.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: photo biostimulation
Description: the intervention is a type of wavelength around 820 nm. this method of treatment is totally safe. yet, it has many therapeutic effects on the cellular level as well as tissue and organ level. during treatment with laser, the patient does not feel any specific sensation.
Study: NCT05526729

Intervention type: OTHER
Intervention: Beovu
Description: Prospective observational study. There is no treatment allocation. Patients prescribed with Beovu for the first time for diabetic macular edema are eligible to enroll into this study.
Study: NCT05248737

Intervention type: DIETARY_SUPPLEMENT
Intervention: DHA/EPA bioenhanced chicken
Description: Chicken fed on a high DHA/EPA diet

Intervention type: DIETARY_SUPPLEMENT
Intervention: DHA/EPA bioenhanced chicken
Description: Chicken fed on a high DHA/EPA diet

Intervention type: DIETARY_SUPPLEMENT
Intervention: 25(OH)D bioenhanced chicken
Description: Chicken fed on a high 25(OH)D diet

Intervention type: DIETARY_SUPPLEMENT
Intervention: 25(OH)D bioenhanced chicken
Description: Chicken fed on a high 25(OH)D diet
Study: NCT06007144

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SPIRION Laryngeal Pacemaker System Implantation and follow-up
Description: Timeline of Visits~* Screening~* Baseline: Official baseline, assessment primary \& secondary objectives~* Implantation of device~* Activation \& fitting: Baseline active device; implanted device has just been activated; assessment of secondary objectives only~* 8 FU Visits over 2 years after activation; Includes~  * Baseline Switch Off: results of the visit preceding a 14-day switch-off of the device; assessment of secondary objectives only~ * Endpoints for~    * Pivotal phase: 12 months after activation; official endpoint for assessment of primary \& secondary objectives~   * Active post-pivotal phase: 24-month follow-up; endpoint for all secondary objectives~   * Switch Off: 2 Visits; assessment of secondary objectives only~ * Repeated checkpoints to assess device effects over 2 years: 5 visits; assessment of secondary objectives only~Device shall increase respiratory patency during inspiration, assessed by normalized PIF; other outcome measures are used to assess secondary objectives
Study: NCT06083090

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Yogatherapy
Description: The experimental arm will benefit from support by a physiotherapist trained in yoga, in a group for ten weeks with two weekly sessions of approximately 1 hour each. A new yoga program adapted for the axSPA will be implemented.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy
Description: The comparator arm will benefit from support by a physiotherapist, in groups for ten weeks at the rate of two weekly sessions of approximately 1 hour each. An already existing program adapted for the axSPA will be implemented.
Study: NCT05247268

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Megestrol Acetate 160 MG Oral Tablet
Description: At a dosage of 160 mg/day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Medroxyprogesterone Acetate 500 MG
Description: At a dosage of 500 mg/day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triprorelin Acetate
Description: Intramuscular injection of 3.75mg was given 4 weeks apart and the maximum use are 6 courses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole 2.5mg
Description: At a dosage of 2.5mg/day and no more than 24 weeks
Study: NCT05425836

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard oxygen therapy
Description: nasal cannula
Study: NCT06297525

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STP938
Description: Small molecule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STP938
Description: Small molecule
Study: NCT05651503

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics
Description: In our study oral probiotics Lactobacillus salivarius Oral S1 11 (Prodilac Oral, Frezyderm) will be tested in two Experimental groups

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics
Description: In our study oral probiotics Lactobacillus salivarius Oral S1 11 (Prodilac Oral, Frezyderm) will be tested in two Experimental groups

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet
Description: In order to avoid possible bias, probiotics will be compared with placebo lozenges/no probiotic in two Control groups

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet
Description: In order to avoid possible bias, probiotics will be compared with placebo lozenges/no probiotic in two Control groups
Study: NCT05425836

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HFNC
Description: High flow nasal cannula
Study: NCT05561803

Intervention type: RADIATION
Intervention: Photobiomodulation Therapy
Description: Focal low-level laser therapy, Red Laser (wavelength 633 nm to 685 nm), or Infrared Laser Laser (wavelength 780 nm to 830 nm), with a low-intensity laser equipment of 100 mW and a cross-sectional area of the device beam of 0.0434 cm². The parameters are 1 to 3 J per point, with equidistant points of 1.5 to 2 cm, covering the entire length of the open lesion. Therapy is carried out every 48 hours until the total wound healing, regardless of the number of sessions required.
Study: NCT04973852

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ekso
Description: Exoskeleton walking
Study: NCT06250673

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Diet experiment
Description: For the isotretinoin users

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Diet experiment
Description: For the isotretinoin users
Study: NCT04943679

Intervention type: DRUG
Intervention: Anti-PD-1/PD-L1
Description: Intravenous injection for up to 2 years

Intervention type: DRUG
Intervention: PEG-Interferon Alfa
Description: 3 µg/kg every week by subcutaneous injection for up to 2 years
Study: NCT05432427

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 64Cu-DOTATATE and 18F-FDG
Description: All participants will get a 64Cu-DOTATATE-PET and 18F-FDG-PET/CT.
Study: NCT05231980

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alpha lipoic acid (ALA)
Description: ALA is sold as a dietary supplement, either by itself or incorporated into a multivitamin product. it also has anti-oxidant effect.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alpha lipoic acid (ALA)
Description: ALA is sold as a dietary supplement, either by itself or incorporated into a multivitamin product. it also has anti-oxidant effect.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline (PTX)
Description: Pentoxifylline is a methylxanthine derivative which acts as a vasodilator by increasing blood flow to tissues, inhibits inflammatory responses, and reduces blood viscosity by impeding platelet aggregation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline (PTX)
Description: Pentoxifylline is a methylxanthine derivative which acts as a vasodilator by increasing blood flow to tissues, inhibits inflammatory responses, and reduces blood viscosity by impeding platelet aggregation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clomiphene Citrate
Description: is a medication used to treat infertility in women who do not ovulate

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clomiphene Citrate
Description: is a medication used to treat infertility in women who do not ovulate

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clomiphene Citrate
Description: is a medication used to treat infertility in women who do not ovulate

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clomiphene Citrate
Description: is a medication used to treat infertility in women who do not ovulate
Study: NCT06189794

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rosa damascena oil
Description: Essential oils will used by inhalation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rosa damascena oil
Description: Essential oils will used by inhalation

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Rosa damascena oil
Description: Essential oils will used by inhalation
Study: NCT05787015

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vaccine Norms Feedback
Description: Personalized normative feedback pertaining to normative misperceptions about vaccination rates and hesitant attitudes.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Alcohol Norms Feedback
Description: Personalized normative feedback pertaining to normative misperceptions about alcohol use.
Study: NCT06192368

Intervention type: DEVICE
Group type: OTHER
Intervention: INSPIRE
Description: Virtual reality application for relaxing.
Study: NCT04033692

Intervention type: DEVICE
Intervention: JuggerKnot Mini Soft Anchor
Description: Patient who have been implanted with one or more JuggerKnot Mini Soft Anchor(s) who have undergone repair, repositioning or reattachment of soft tissues, ligament and tendons to the mandible is require for surgical stabilization of the TMJ articular disc.
Study: NCT06192368

Intervention type: DEVICE
Group type: OTHER
Intervention: INSPIRE
Description: Virtual reality application for relaxing.

Intervention type: DEVICE
Group type: OTHER
Intervention: Tablet
Description: Gaming tablet

Intervention type: DEVICE
Group type: OTHER
Intervention: Tablet
Description: Gaming tablet
Study: NCT04271527

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cognitive fusion targeted biopsy
Description: A cognitive fusion targeted biopsy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: cognitive fusion targeted biopsy
Description: A cognitive fusion targeted biopsy
Study: NCT00748735

Intervention type: PROCEDURE
Intervention: Implantation of a cardiac resynchronization therapy device

Intervention type: PROCEDURE
Intervention: Echocardiography (myocardial deformation imaging)
Study: NCT05602909

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Guided biaxial alveolar distraction device
Description: A crestal incision will be done, a surgical guide will be placed to assist the correct position of osteotomy, an Extraosseous alveolar distractor will be placed on the ridge to mark screw sites and then will be removed, A distractor will be stabilized to the basal segment with a monocortical screw.
Study: NCT06189105

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: miss alice face it you love me serum
Description: Facial serum with niacinamide, plant-based collagen and peptides will be applied by each participant to the treatment site according to randomization protocol every evening

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: No treatment (usual skincare rutine)
Description: No treatment (usual skincare rutine)
Study: NCT04461418

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glucocorticoid therapy
Description: The study intervention is defined as treatment with either prednisone or dexamethasone as palliative therapy for the control of neurological symptoms; patients with symptomatic brain metastases with a requirement for glucocorticoid therapy will be treated with an available, standard-of-care immune checkpoint inhibitor regimen.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glucocorticoid therapy
Description: The study intervention is defined as treatment with either prednisone or dexamethasone as palliative therapy for the control of neurological symptoms; patients with symptomatic brain metastases with a requirement for glucocorticoid therapy will be treated with an available, standard-of-care immune checkpoint inhibitor regimen.
Study: NCT05998096

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine-Based Energy Drink
Description: Caffeine-based energy drink containing 200 mg caffeine

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo void of all active ingredients
Study: NCT05384392

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Recorded interview
Description: A recorded clinical interview, transcribed verbatim and blinded analyzed

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical scales
Description: Answering to clinical scales : PANSS (Positive and Negative Syndrome Scale); BPRS (Brief Psychiatric Rating Scale); CDSS (Calgary Depression Scale for Schizophrenia); MADRS (Montgomery-Åsberg Depression Rating Scale); Altman; YMRS (Young Mania Rating Scale); GAF (Global Assessment of Functioning); SF-36 (36-Item Short Form Survey); CGI-S (Clinical Global Impression Scale) et CGI-I (CGI-Improvement)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Blood collection of inflammatory markers (IL-1, sIL-2R, IL-4, IL-6, IL-8 and TNF levels) and 2 EDTA tubes and 2 dry tubes for biological collection (plasma bank and serum bank). This blood sample will be taken during routine sampling.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MRI scans of the brain
Description: The MRI scans of the brain will be performed. This exam is performed in routine care in the context of this pathology
Study: NCT06374784

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole
Description: Atraumatic extraction of non-restorable teeth, then the extracted tooth will be prepared and demineralized using hydrochloric acid (HCL) acid as particulate demineralized dentin graft and processed with injectable platelet rich fibrin. The injectable PRF will be mixed with 5mg/ml metronidazole first then added to the particulate demineralized dentin graft forming sticky demineralized tooth graft with slowly released metronidazole then inserted in the extraction socket and covered then suturing

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF
Description: Atraumatic extraction of non-restorable teeth, then the extracted tooth will be prepared and demineralized using hydrochloric acid (HCL) acid as particulate demineralized dentin graft. The injectable PRF will be added to the particulate demineralized dentin graft forming sticky demineralized tooth graft then inserted in the extraction socket and covered then suturing

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Alveolar ridge preservation using autogenous demineralized dentin graft alone
Description: Atraumatic extraction of non-restorable teeth, then the extracted tooth will be prepared and demineralized using hydrochloric acid (HCL) acid inserted in the extraction socket as particulate demineralized dentin graft
Study: NCT06206330

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Platelet rich plasma
Description: After application of platelet rich plasma after surgery, the patients have examined for infection, hematoma, pain, recurrence and the time of epithelialization of the wound.
Study: NCT05239949

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hypopressive exercises
Description: For hypopressive exercises, the patient will be instructed to inhale, then breathe to expand the ribcage, and then exhale completely. Hold the breath out before relaxing core and ribcage.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic floor exercises
Description: For pelvic floor exercises, the patient is instructed to hold each contraction for 6 seconds.
Study: NCT05391984

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activity oriented treatment
Description: 15 patients will be treated with activity oriented therapy. All subjects will receive 20 therapeutic sessions, 5 times a week over the time span of 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structural oriented treatment
Description: 15 patients will be treated with structural oriented therapy. All subjects will receive 20 therapeutic sessions, 5 times a week over the time span of 4 weeks.
Study: NCT05169645

Intervention type: OTHER
Intervention: Physical activity monitoring - Symptom monitoring
Description: This is an observational study. There is no intervention outside the collection of data from participants. Consenting participants in the study will be provided with a Fitbit activity tracker and asked to wear it for a period of three months.~The Fitbit measures:~* Physical activity using daily step count~* Additional physical activity entries~* Heart rate~* Sleep quality~* Calories burned~* Food log~Participants will be asked to download an app onto their smart phone entitled Athena CX. This app is designed to capture:~* Urticaria symptomatology using the urticaria control test~* Symptoms of depression using 2 items from the PHQ 9~* Symptoms of anxiety using two items from the GAD~* Short form self-compassion scale