TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04214327

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Strengthening Families Program Online eLearning Game
Description: Families (parent/caregiver and children) are to play-test a highly interactive online gamified version of the Strengthening Families Program called SFP Online, with 10 lessons that utilize three 10-minute mini-sessions and games that teach parents evidence-based parenting and family relationship skills and teach youth social, life, and alcohol and drug refusal skills. Skills are reinforced through gaming. Game points are achieved by right answers to self-correcting mini-quizzes for low-stakes failure and through actual reported home practice of the skills. The SFP parenting skills have been shown to reduce risk factors and increase protective factors that prevent youth substance abuse.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Strengthening Families Program Online eLearning Game
Description: Families (parent/caregiver and children) are to play-test a highly interactive online gamified version of the Strengthening Families Program called SFP Online, with 10 lessons that utilize three 10-minute mini-sessions and games that teach parents evidence-based parenting and family relationship skills and teach youth social, life, and alcohol and drug refusal skills. Skills are reinforced through gaming. Game points are achieved by right answers to self-correcting mini-quizzes for low-stakes failure and through actual reported home practice of the skills. The SFP parenting skills have been shown to reduce risk factors and increase protective factors that prevent youth substance abuse.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SFP Home-use DVD
Description: Family views an 11-session SFP video series online or at home using a DVD that contains the same program and lesson content as the online condition; however, the lesson material is more static without the interaction required in the gamified version of SFP Online.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Wait-Listed Control
Description: Families receive no active intervention for 22 weeks; however, during this wait time, participants receive weekly email reminders that contain riddles and puzzles for youth and parents receive nutritional information and food preparation recipes. Following conclusion of the initial trial the wait-listed control sites are then administered the 10-session SFP Online intervention
Study: NCT05170269

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BT097
Description: Subjects will receive BT097 200 U per kg of maternal body weight intravenously every 2 weeks until at least GW 17
Study: NCT06378697

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK111
Description: Drug: AK111 subcutaneous injection at week 0,1, 4 and 4-weekly thereafter until week 48.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo+AK111
Description: Placebo+AK111 placebo subcutaneous injection at week 0,1, 4,8 and 12 follow AK111 4-weekly thereafter until week 48.
Study: NCT05901155

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MedAL-mentor
Description: MedAL-mentor is a near real-time monitoring and benchmarking dashboard based on data collected through ePOCT+, providing direct feedback on several clinical indicators (antibiotic prescription, performance of key measurements, signs, and diagnostic tests).
Study: NCT00959777

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-3031

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Filgrastim
Study: NCT06141200

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NW Roselle
Description: NW Roselle is a powdered extract from the flowers of Hibiscus Sabdariffa (300mg) and the leaves of Olea europaea (200 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Captopril 25Mg Tab
Description: Active Comparator
Study: NCT05475847

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Tumor Infiltrating Lymphocytes (C-TIL052A) Injection
Description: C-TIL052A injection followed by injection of IL-2
Study: NCT06728241

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: VR Games
Description: Patients randomized to this condition will receive a total of ten sessions of VR games.
Study: NCT05203705

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 1, for 12 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 2, for 12 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 3, for 12 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 4, for 12 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Enoxaparin
Description: Enoxaparin, for 12 days
Study: NCT04864366

Intervention type: DRUG
Intervention: Tenofovir Alafenamide 25 MG [Vemlidy]
Description: TAF is administered as a 25mg/tablet, taken orally with food once daily, for 48 weeks.

Intervention type: DRUG
Intervention: Tenofovir Alafenamide 25 MG [Vemlidy]
Description: TAF is administered as a 25mg/tablet, taken orally with food once daily, for 48 weeks.
Study: NCT06544850

Intervention type: OTHER
Intervention: experimental group
Description: Oswestry Low Back Pain Questionnaire will be used to assess functional limitations in daily life activities of patients with low back pain. Recognize mobile application will be used to assess lateralization performance. Evaluation will be made with hand, foot and back modules of this application. Reaction time and accuracy given at the end of the application will be recorded. The most accurate response instruction will be given in the shortest possible time. Visual Analog Scale (VAS) will be used to measure general pain status of patients. Tampa Kinesiophobia Scale will be used to assess fear of movement. Pain catastrophizing level will be assessed with Pain Catastrophizing Scale. Two-point discrimination device will be used to assess two-point discrimination. Central Sensitization Inventory will be used for central sensitization findings.

Intervention type: OTHER
Intervention: control group
Description: Healthy volunteer participants who meet the inclusion criteria will be evaluated with the tests applied to the experimental group
Study: NCT04831047

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxymetazoline hydrochloride 0.1% ophthalmic solution
Description: One drop of Upneeq (Oxymetazoline hydrochloride 0.1% ophthalmic solution) will be applied to the ocular surface of each eye.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Placebo
Description: One drop of placebo (balanced saline solution) will be applied to the ocular surface of each eye.
Study: NCT05635175

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hip abductors physiotherapy self training
Description: hip abductors self training program during 7 to 10 weeks associate with a PFMT

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard pelvic floor muscle training
Description: Standard pelvic floor muscle training

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard pelvic floor muscle training
Description: Standard pelvic floor muscle training

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard pelvic floor muscle training self training
Description: Standard pelvic floor muscle training self training
Study: NCT04411186

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Enhanced Recovery After Surgery (ERAS) Protocol
Description: Subjects receive standard MUSC ERAS protocol - fluid intake, hydration, anti-emetics, pain control, and several other considerations.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ERAS and 5 Lung Protective Interventions
Description: Subjects will receive the standard MUSC ERAS protocol - fluid intake, hydration, anti-emetics, pain control, and several other considerations. The subject will also receive the following lung protective interventions:~Pressure control ventilation-volume guaranteed (PCV-VG) ventilation at approximately 7cc/kg of predicted body weight (derived from combination of sex and height) Positive end-expiratory pressure (PEEP) 7cm H2O5 Immediately post intubation recruitment breath (30cm water for 30 seconds) Every 1 hour recruitment breath (30cm water for 30 seconds) 40% FIO2 initially - titrate up as necessary to maintain SPO2 \>94%
Study: NCT04669379

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EXPECT: Preoperative optimization of patient's expectations
Description: Patients work through an online-tool (around 30 minutes). This preoperative intervention aims to optimize patients' expectations by focusing on positive and realistic expectations regarding the surgery-benefits and recovery process, giving information, and giving advice for coping resources.
Study: NCT05616377

Intervention type: OTHER
Intervention: Surgery or Radiotherapy
Description: Participants who underwent target therapy and surgery or radiotherapy were divided into target therapy + local therapy group. Participants who underwent target therapy alone were divided into target therapy alone group

Intervention type: OTHER
Intervention: before or after target therapy
Description: Participants who underwent surgery or radiotherapy before target therapy were divided into local therapy before target therapy group. Participants who underwent surgery or radiotherapy after target therapy were divided into local therapy after target therapy group.
Study: NCT06723899

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CanWork
Description: CanWork is an online, occupational therapy intervention to develop knowledge and skills to manage cancer-related symptoms that interfere with return to work. It consists of five, 90-minute group-based modules and an individual meeting between the occupational therapist facilitator and each participant. Each of the five-week group-based modules consists of two components: (i) education and peer-led discussion of cancer-related symptom management and supports available to manage difficulties in work and (ii) goal setting to facilitate application of knowledge and skills to work-related activities. Weekly topics include managing fatigue in work, understanding cancer-related cognitive impairments, strategies for managing physical and mental health in work and effective communication with employers and colleagues. The individual meeting between each participant and the occupational therapist is focused on designing a tailored return to work plan for each participant.
Study: NCT06737796

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Finger Feeding
Description: feeding method
Study: NCT05347017

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Alveolar ridge preservation using autogenous demineralized dentin block graft
Description: Atraumatic extraction of non restorable tooth, then the extracted tooth will be prepared and demineralized by HCL acid and inserted as demineralized dentin block graft in the socket
Study: NCT06737796

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: syringe feeding
Description: feeding method
Study: NCT06738706

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intermittent hypoxia-hyperoxia treatment
Description: The intermittent hypoxia-hyperoxia training refers to 4 cycles of 10-minute hypoxia inhalation interspersed with 20-minute hyperoxia, which is performed once daily for 14 days within 2 to 3 weeks.
Study: NCT05347017

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Alveolar ridge preservation using autogenous bone block graft
Description: Atraumatic extraction of non restorable tooth, then the autogenous bone block graft will be harvested from the maxillary tuberosity and reshaped and inserted into the socket
Study: NCT06741085

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: osimertinib
Description: oral EGFR-TKI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: osimertinib
Description: oral EGFR-TKI

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: stereotactic radiosurgery (SRS)
Description: 0-20mm-18Gy x 1, 21Gy x 1 ,9Gy x 3~20mm or larger- 9Gy x 3, 6Gy x 5, 5Gy x 5
Study: NCT06740799

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quizartinib
Description: Participants will receive a single oral dose of 30 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quizartinib
Description: Participants will receive a single oral dose of 30 mg
Study: NCT06737718

Intervention type: OTHER
Intervention: Eye tracking
Description: The eye-tracking session will take place in the Pediatric Radiology department of Necker Hospital. The child will be seated in front of a computer screen. Films and images with social and/or non-social content will be shown to the children. The session will be unique, will last approximately 15 minutes and will not involve any constraints for the child.~Eye tracking allows to measure where and how a person looks. An infrared light is emitted towards the subject's eye. It is reflected there and a camera records the reflections generated, allowing a real-time calculation of the position of the gaze. The technique is harmless and non-invasive.

Intervention type: OTHER
Intervention: Eye tracking
Description: The eye-tracking session will take place in the Pediatric Radiology department of Necker Hospital. The child will be seated in front of a computer screen. Films and images with social and/or non-social content will be shown to the children. The session will be unique, will last approximately 15 minutes and will not involve any constraints for the child.~Eye tracking allows to measure where and how a person looks. An infrared light is emitted towards the subject's eye. It is reflected there and a camera records the reflections generated, allowing a real-time calculation of the position of the gaze. The technique is harmless and non-invasive.

Intervention type: OTHER
Intervention: Data collection from patients' medical files
Description: Data collection from patients' medical files:~* Brain imaging data if this examination was carried out as part of the patient's care,~* Angelman syndrome genotypes.
Study: NCT06740253

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Placebo intravaginal ring (IVR)
Description: Antibody-Based Nonhormonal Placebo Contraceptive Intravaginal Ring
Study: NCT06740526

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sibeprenlimab
Description: Sibeprelimab SC (Period 1)~Sibeprelimab SC (Period 2)
Study: NCT06736678

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oral Immunonutrition
Description: Patients receive enteral immunonutrition, Oral Impact® Nestle for 6 weeks from one week before radiotherapy;
Study: NCT06736912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IN-114199 2.5mg or placebo
Description: IN-114199 2.5mg or placebo (1 Tablet, QD)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IN-114199 2.5mg or placebo
Description: IN-114199 2.5mg or placebo (1 Tablet, QD)
Study: NCT05318833

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS7415
Description: Drug: HRS7415
Study: NCT04886245

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video sequences
Description: videos will be made of each participant, during the realization of 5 movements that are the simple closure of the eyelids, the forced closure of the eyelids, the labial protrusion on the sound \[o\], the labial protrusion on the sound \[pu\] and the wide smile uncovering the teeth.~Then, a video sequence will be realized thanks to the dedicated software Tobii Pro Lab®.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Video sequences
Description: videos will be made of each participant, during the realization of 5 movements that are the simple closure of the eyelids, the forced closure of the eyelids, the labial protrusion on the sound \[o\], the labial protrusion on the sound \[pu\] and the wide smile uncovering the teeth.~Then, a video sequence will be realized thanks to the dedicated software Tobii Pro Lab®.
Study: NCT05717205

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: technetium scitigraphy
Description: patients will have a technetium scintraphy confirming or ruling out gastroparesis. Then the patients will have a gastroscopy with tissue samples from antrum and fundus. During gastroscopy an endo-flip ballon will meassure the distensibility in pylorus.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: technetium scitigraphy
Description: patients will have a technetium scintraphy confirming or ruling out gastroparesis. Then the patients will have a gastroscopy with tissue samples from antrum and fundus. During gastroscopy an endo-flip ballon will meassure the distensibility in pylorus.
Study: NCT04918472

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MCCE
Description: Mangetically controlled capsule endoscopy will be performed
Study: NCT04940585

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ROSE Program
Description: The program includes 6 group sessions and an individual session 4-6 weeks after birth. Each session will last 60 minutes and will be conducted over Webex. The key areas that will be discussed during the sessions include: Psychoeducation, Adjusting to life with baby, Effective communication, Asking for what you need, and Planning for the future.
Study: NCT04869852

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food
Description: 85g mango, 4x/week
Study: NCT04964583

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hydroxychloroquine with Azithromycin
Description: Fixed combination of Hydroxychloroquine with Azithromycin 200 mg / 250 mg one tablet every 12 hours for five days and continue with Hydroxychloroquine 200 mg one tablet every 12 hours for 5 more days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxychloroquine with Azithromycin
Description: Fixed combination of Hydroxychloroquine with Azithromycin 200 mg / 250 mg one tablet every 12 hours for five days and continue with Hydroxychloroquine 200 mg one tablet every 12 hours for 5 more days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Hydroxychloroquine with Azithromycin
Description: Fixed combination of Hydroxychloroquine with Azithromycin 200 mg / 250 mg one tablet every 12 hours for five days and continue with Hydroxychloroquine 200 mg one tablet every 12 hours for 5 more days.
Study: NCT05707949

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atogepant
Description: Oral Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atogepant
Description: Oral Tablet
Study: NCT05730114

Intervention type: DRUG
Intervention: Antiplatelet Drug
Description: anti-P2Y12 oral agent administered during primary percutaneous coronary intervention.

Intervention type: DRUG
Intervention: Antiplatelet Drug
Description: anti-P2Y12 oral agent administered during primary percutaneous coronary intervention.

Intervention type: DRUG
Intervention: Antiplatelet Drug
Description: anti-P2Y12 oral agent administered during primary percutaneous coronary intervention.
Study: NCT05526365

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reduced Idea Density
Description: Question idea density reduced (ratio of propositions to total words used).
Study: NCT05395364

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention program BeE-school
Description: The intervention program will be co-developed and directed to school professionals. It will be based on the promotion of health literacy and lifestyles.
Study: NCT05869045

Intervention type: OTHER
Intervention: Diaphragm shortening fraction measurement by point-of-care ultrasound.
Description: A noninvasive and feasible method to assess diaphragmatic function and predict the prognosis of patients with respiratory failure presenting to the emergency department. The method consists of measuring the diaphragmatic thickness at the end of inspiration and expiration using a linear probe placed in the subcostal region and calculating the percentage of change using the formula: diaphragmatic thickness at the end of inspiration - diaphragmatic thickness at the end of expiration/diaphragmatic thickness at the end of expiration×100. A value lower than 10% indicates diaphragmatic dysfunction and a higher risk of adverse outcomes.

Intervention type: OTHER
Intervention: Diaphragm shortening fraction measurement by point-of-care ultrasound.
Description: A noninvasive and feasible method to assess diaphragmatic function and predict the prognosis of patients with respiratory failure presenting to the emergency department. The method consists of measuring the diaphragmatic thickness at the end of inspiration and expiration using a linear probe placed in the subcostal region and calculating the percentage of change using the formula: diaphragmatic thickness at the end of inspiration - diaphragmatic thickness at the end of expiration/diaphragmatic thickness at the end of expiration×100. A value lower than 10% indicates diaphragmatic dysfunction and a higher risk of adverse outcomes.
Study: NCT05707884

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: critical care management
Description: The different sedation methods result in considerable differences in terms of set-up costs and the management of the patient, which will be examined in a direct comparison.
Study: NCT06317038

Intervention type: DEVICE
Group type: OTHER
Intervention: Total 30 Contact Lens
Description: Patients will be give a contact lens for 1 month
Study: NCT05418660

Intervention type: DRUG
Intervention: Immunotherapy
Description: At least 24 months with Pembrolizumab, Nivolumab or Atezolizumab in any treatment line

Intervention type: DRUG
Intervention: Immunotherapy
Description: At least 24 months with Pembrolizumab, Nivolumab or Atezolizumab in any treatment line
Study: NCT06305442

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Microbiota-Directed Food
Description: MDF is a microbiota directed food for malnourished children aged 6 months and above. It is in sachet form. The sachet contains 92 gm of supplements and provides approximately 506 kcal.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ready-to-Use Supplementary Food
Description: RUSF is standard ready-to-use supplementary food for MAM children aged 6 months and above.
Study: NCT05152199

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Cystoscopy - with use of obturator sheath
Description: The intervention arm will include the use of the obturator sheath upon entry into the urethra during rigid cystoscopy.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cystoscopy - without use of obturator sheath
Description: The intervention arm will not include the use of the obturator sheath upon entry into the urethra during rigid cystoscopy, but will consist of using the telescope under direct visualization.