TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05330494

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation(TEAS)
Description: transcutaneous electrical acupoint stimulation (TEAS), the modern therapies derived from traditional acupuncture, which could activate nerve endings or fibers and generate action potentials.s. TEAS uses self-adhesive electrodes placed on the surface of acupoints, instead of needles for electrical stimulation.The resulting stimulation signals, which are transmitted to the spinal cord and brain, stimulate the central nervous system to generate specific chemical mediators to induce relevant physiological effects.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation(TEAS)
Description: transcutaneous electrical acupoint stimulation (TEAS), the modern therapies derived from traditional acupuncture, which could activate nerve endings or fibers and generate action potentials.s. TEAS uses self-adhesive electrodes placed on the surface of acupoints, instead of needles for electrical stimulation.The resulting stimulation signals, which are transmitted to the spinal cord and brain, stimulate the central nervous system to generate specific chemical mediators to induce relevant physiological effects.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation(TEAS)
Description: transcutaneous electrical acupoint stimulation (TEAS), the modern therapies derived from traditional acupuncture, which could activate nerve endings or fibers and generate action potentials.s. TEAS uses self-adhesive electrodes placed on the surface of acupoints, instead of needles for electrical stimulation.The resulting stimulation signals, which are transmitted to the spinal cord and brain, stimulate the central nervous system to generate specific chemical mediators to induce relevant physiological effects.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: transcutaneous electrical acupoint stimulation(TEAS)
Description: transcutaneous electrical acupoint stimulation (TEAS), the modern therapies derived from traditional acupuncture, which could activate nerve endings or fibers and generate action potentials.s. TEAS uses self-adhesive electrodes placed on the surface of acupoints, instead of needles for electrical stimulation.The resulting stimulation signals, which are transmitted to the spinal cord and brain, stimulate the central nervous system to generate specific chemical mediators to induce relevant physiological effects.
Study: NCT06205563

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: high-intensity interval training
Description: High-intensity interval training (to significantly faster breathing, a significant increase in breathing depth, a significant increase in heart rate, sweating, and the need to stop exercising and adjust your breathing before you can speak; Energy expenditure (METy ≥6.00 in children) : Participants randomly assigned to HIIT will perform a 10-minute warm-up at 60-70% of their maximum heart rate (HRmax). After this, they will walk, run, or bike at 85-95% of their maximum heart rate for four sessions of four minutes each, with three minutes of active recovery (50-70% of their maximum heart rate) in between. The participants were given a five-minute cooling-off period at the end, for a total of 40 minutes of exercise. Participants will be required to participate in supervised exercise classes at least five times and up to seven times a week for 12 weeks. Each participant will be free to wear a smart electronic sports bracelet, which can be used to punch in sports.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: moderate intensity continuous training
Description: Moderate intensity continuous training (rapid breathing, rapid heart rate, slight sweating, but still able to talk easily; Energy expenditure (children METy) 3.00 to 5.99) : Participants randomly assigned to the MICT group will walk, run, or cycle continuously for 40 minutes at 60-70% HRmax. Participants will be required to participate in supervised exercise classes at least five times and up to seven times a week for 12 weeks. Each participant will be free to wear a smart electronic sports bracelet, which can be used to punch in sports.
Study: NCT05284214

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sargramostim
Description: Sargramostim for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sargramostim
Description: Sargramostim for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab-containing therapy
Description: Treatment for cancer containing ipilimumab at either 1 mg/kg or 3 mg/kg, intravenously..

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab-containing therapy
Description: Treatment for cancer containing ipilimumab at either 1 mg/kg or 3 mg/kg, intravenously..
Study: NCT05627232

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tazemetostat
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liposome-encapsulated Daunorubicin-Cytarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liposome-encapsulated Daunorubicin-Cytarabine
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration and Biopsy
Description: Undergo bone marrow aspiration and biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration and Biopsy
Description: Undergo bone marrow aspiration and biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Description: Given PO
Study: NCT04919031

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Inspiratory muscle trainer
Description: POWER breathe IMT is a drug-free, hand-held breathing training device. The medical term for this type of breathing training is Inspiratory Muscle Training, or IMT. POWER breathe IMT exercises the main muscles you use to breathe in, primarily your diaphragm and intercostal

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inspiratory muscle trainer
Description: POWER breathe IMT is a drug-free, hand-held breathing training device. The medical term for this type of breathing training is Inspiratory Muscle Training, or IMT. POWER breathe IMT exercises the main muscles you use to breathe in, primarily your diaphragm and intercostal

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: diaphragmatic release
Description: diaphragmatic release is a manual technique use for restoring the ability of the diaphragm to go through a full range of motion
Study: NCT00693537

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: 4 weeks in-hospital exercise training (6x15 min bicycle/day, 5 days/week) followed by a 5 months ambulatory exercise program (30 min ergometer/day, 5 days/week, plus 1h group exercise/week)
Study: NCT06497283

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Binaural sound
Description: Binaural sound: Binaural sound will be applied.
Study: NCT04595474

Intervention type: DEVICE
Intervention: Transient Elastography
Description: Transient elastography is a noninvasive imaging modality used to assess NAFLD and advanced fibrosis
Study: NCT05769413

Intervention type: OTHER
Intervention: Patient Participation Form
Description: A form that consists of revised osteoporosis knowledge test, osteoporosis self-efficacy scale, and osteoporosis health belief scale.
Study: NCT05738369

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Biogaia L. reuteri Prodentis® lozenges
Description: Participants were instructed to use the lozenges twice daily after brushing their teeth; once in the morning and once in the evening

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Hersheyland Ice Breakers Mints sugar free lozenges
Description: Hersheyland Ice Breakers Mints sugar free lozenges
Study: NCT04307589

Intervention type: OTHER
Intervention: Observation
Description: An observational follow-up study will be implemented over a period of 2 years, consisting of 3 test occasions with a fixed time interval of 1 year in between (T0 = baseline, T1 = 12 months, T2 = 24 months). Data will be collected in participants who provide grandchild care in a non-residential grandparent context as well as in a sample of non-caregiving grandparents and a sample of middle-aged and older adults not being a grandparent. All three samples will thus be prospectively monitored over a period of 2 years.

Intervention type: OTHER
Intervention: Observation
Description: An observational follow-up study will be implemented over a period of 2 years, consisting of 3 test occasions with a fixed time interval of 1 year in between (T0 = baseline, T1 = 12 months, T2 = 24 months). Data will be collected in participants who provide grandchild care in a non-residential grandparent context as well as in a sample of non-caregiving grandparents and a sample of middle-aged and older adults not being a grandparent. All three samples will thus be prospectively monitored over a period of 2 years.
Study: NCT05786352

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ERAS protocol
Description: The combination of interventions explained in arm descriptions.
Study: NCT05454475

Intervention type: OTHER
Intervention: Change the water injection temperature
Description: Water injection is a routine procedure for endoscopy of small probe ultrasound, and our intervention is to change the water temperature and observe the effects of different water temperatures on patient safety and comfort.

Intervention type: OTHER
Intervention: Change the water injection temperature
Description: Water injection is a routine procedure for endoscopy of small probe ultrasound, and our intervention is to change the water temperature and observe the effects of different water temperatures on patient safety and comfort.
Study: NCT04307589

Intervention type: OTHER
Intervention: Observation
Description: An observational follow-up study will be implemented over a period of 2 years, consisting of 3 test occasions with a fixed time interval of 1 year in between (T0 = baseline, T1 = 12 months, T2 = 24 months). Data will be collected in participants who provide grandchild care in a non-residential grandparent context as well as in a sample of non-caregiving grandparents and a sample of middle-aged and older adults not being a grandparent. All three samples will thus be prospectively monitored over a period of 2 years.
Study: NCT05790915

Intervention type: COMBINATION_PRODUCT
Intervention: Standardized interventions
Description: Standardized interventions according organ dysfunction
Study: NCT06497283

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Binaural sound
Description: Binaural sound: Binaural sound will be applied.
Study: NCT06352151

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine Physiotherapy Group
Description: Children with Down syndrome who receive routine physical therapy treatment in special education centers will undergo evaluation after eight weeks of treatment, followed by a control evaluation after 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Orofacial Treatment Group
Description: The orofacial treatment group receives therapeutic orofacial treatment in addition to routine physiotherapy treatment. Each week, one or two target exercises will be taught to the child with Down syndrome, and the exercises will gradually increase throughout the process. Parental involvement will be encouraged during the treatment to ensure active participation in therapy.~The goals of the therapy are as follows:~First Goal: Nasal hygiene and Sleep hygiene education~Second Goal: Nasal Breathing Exercise Training~Third Goal: Creating Awareness of Tongue Resting Position~Fourth Goal: Creating Lip Position Awareness - Lip Exercises~Goal Five: Chewing Muscle Exercises~Sixth Goal: Strengthening the Soft Palate~Seventh Goal: Reshaping Correct Swallowing

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Yoga Group
Description: The therapeutic yoga group receives therapeutic yoga treatment and routine physiotherapy treatment. Children with Down syndrome will be given yoga exercises suitable for their age.
Study: NCT05483699

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Squeezing a ball
Description: The children in the squeezing soft ball group were given the ball before the procedure. They were told to squeeze and loosen the ball with the hand that was not used for the procedure while intravenous cannula was being inserted.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blowing bubbles
Description: The children in the blowing bubble group were shown the bubble blower before intravenous cannulation and they were told how bubbles were formed and how they would blow. During intravenous cannulation, the child blew the blower

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kaleidoscope
Description: Children in the Kaleidoscope group were given the kaleidoscope before intravenous cannulation and they were shown how to use it. The children were told to look at the kaleidoscope during the procedure until the procedure ended
Study: NCT05501080

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Super selective adrenal artery embolization
Description: Superselective adrenal arterial embolization is an operation to inject embolic agent into adrenal artery through catheter to embolize part of adrenal gland, so as to reduce the secretion of adrenal hormone and reduce blood pressure.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Spironolactone
Description: Aldosterone receptor antagonists are recommended by guidelines for the treatment of bilateral primary aldosteronism.
Study: NCT06400290

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous coronary intervention (PCI)
Description: Coronary artery stenting for stable angina

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Symptom assessment during experimentally induced ischaemia
Description: Transient experimental balloon occlusion across coronary stenosis to determine the symptoms conferred by ischaemia at this stenosis.
Study: NCT05449340

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BEAUTIFY application
Description: Interview with the coordinating nurse in the postoperative period to install the BEAUTIFY application on the patient's smartphone and to train her to record any Patients will monitor their symptoms weekly. In case of toxicity grade \> 2, the nurse will contact the patient for further information.
Study: NCT05929391

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Recycling orthodontic brackets
Description: T0: The adhesive removal will be performed by high-speed hand piece with tungsten carbide bur. the bur will be changed every five attachments. T1: Control group of T0. T2: The adhesive removal will be performed by sandblasting via Micro-etcher.~T3: Control group of T2.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Recycling orthodontic brackets
Description: T0: The adhesive removal will be performed by high-speed hand piece with tungsten carbide bur. the bur will be changed every five attachments. T1: Control group of T0. T2: The adhesive removal will be performed by sandblasting via Micro-etcher.~T3: Control group of T2.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Recycling orthodontic brackets
Description: T0: The adhesive removal will be performed by high-speed hand piece with tungsten carbide bur. the bur will be changed every five attachments. T1: Control group of T0. T2: The adhesive removal will be performed by sandblasting via Micro-etcher.~T3: Control group of T2.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Recycling orthodontic brackets
Description: T0: The adhesive removal will be performed by high-speed hand piece with tungsten carbide bur. the bur will be changed every five attachments. T1: Control group of T0. T2: The adhesive removal will be performed by sandblasting via Micro-etcher.~T3: Control group of T2.
Study: NCT04679623

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Midazolam Injection, 10mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Seizalam
Description: Seizalam, 10 mg
Study: NCT06644833

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation
Description: Transcranial Magnetic Stimulation (rTMS) sessions, targeting the dorsolateral prefrontal cortex, at a frequency of 10 Hz. Each session will last approximately 30 minutes, with 5 sessions per week for 4 to 6 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antidepressant
Description: Selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants, SNRIs
Study: NCT06110936

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous Spinal Direct Current Stimulation
Description: Transcutaneous spinal direct current stimulation (ts-DCS), a neuromodulation technique, is one of the non-invasive brain stimulation techniques. ts-DCS occurs when a continuous and low-intensity electric current passes through electrodes with moist sponges placed on the spinal cord.
Study: NCT05454475

Intervention type: OTHER
Intervention: Change the water injection temperature
Description: Water injection is a routine procedure for endoscopy of small probe ultrasound, and our intervention is to change the water temperature and observe the effects of different water temperatures on patient safety and comfort.
Study: NCT05728840

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Immersive virtual reality gamified cognitive activities
Description: This intervention will include 20 sessions of training with the experimental rehabilitation program using immersive VR cognitive gamified activities, in addition to the standard of care.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Double neuropsychological standard activities
Description: This intervention will include 20 sessions of training using a standard neuropsychological rehabilitation program, in addition to the standard of care.
Study: NCT05510310

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast stimulation
Description: By breast pump
Study: NCT06110936

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Spinal Direct Current Stimulation
Description: Transcutaneous spinal direct current stimulation (ts-DCS), a neuromodulation technique, is one of the non-invasive brain stimulation techniques. ts-DCS occurs when a continuous and low-intensity electric current passes through electrodes with moist sponges placed on the spinal cord.
Study: NCT05510310

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Oxytocin
Description: Oxytocin will be administered intravenously and titrated
Study: NCT03700034

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mHealth Integrated Model of Antenatal Care
Description: In the intervention facilities, antenatal care (ANC) will be provided to all pregnant women using the mIRA electronic decision support system (EDSS) by ANMs (Auxiliary Nurse Midwife), Staff nurses, or Medical Officers (MOs). These frontline healthcare workers (FHWs) will be trained to use the EDSS and will also be provided refresher training on the guideline-recommended processes of ANC. This training will enable them to use the mIRA EDSS in the provision of ANC. Non-physician FHWs (ANMs and staff nurses) will screen, detect, and refer PIH, GDM, and severe anemia cases. They will not prescribe treatments, but will carry out all other duties including diagnosis, referral to the MO to prescribe drugs, provide lifestyle advice, follow-up, and subsequently support adherence to management plans.
Study: NCT06597058

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MAR
Description: Once-daily tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: MAR
Description: Once-daily tablet
Study: NCT06692296

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Balance training over stabilometric platform
Description: The treatment using the stabilometric platform (a total of 20 sessions) generally includes an initial phase (approximately 5 minutes) of training and warm-up in monitor mode, during which the patient becomes familiar with the equipment. The patient then moves on to training library mode, which includes the following subcategories: (1) Stabilometric tracings in both static and dynamic phases (10 minutes); (2) Dexterity exercises in both static and dynamic phases (10 minutes); (3) Imbalance exercises in both static and dynamic phases (10 minutes).~The goal during this phase is to increase the patient's stability limits and provoke balance reactions through load shifts in all directions. The session concludes with 10 minutes of TecnoBody Exergames, which help to automate the functions learned within a more complex activity.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Balance training by means of conventional rehabilitation
Description: Conventional rehabilitation to improve balance includes an initial phase of tissue mobilization, particularly of the foot structures (approximately 5 minutes per foot), in order to prepare them for the subsequent activation phase. This is followed by a phase focused on activating the anti-gravity muscles and aligning the trunk within the chosen setting (10 minutes). The treatment continues with balance training, both static and dynamic, load transfers, and dual-task exercises using external references (15 minutes). The session concludes with functional exercises relevant to the patient's daily life context (10 minutes).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Balance training by means of conventional rehabilitation
Description: Conventional rehabilitation to improve balance includes an initial phase of tissue mobilization, particularly of the foot structures (approximately 5 minutes per foot), in order to prepare them for the subsequent activation phase. This is followed by a phase focused on activating the anti-gravity muscles and aligning the trunk within the chosen setting (10 minutes). The treatment continues with balance training, both static and dynamic, load transfers, and dual-task exercises using external references (15 minutes). The session concludes with functional exercises relevant to the patient's daily life context (10 minutes).
Study: NCT06631183

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-help information based on principles of behavioral activation
Description: Participants will engage with the self-help tool e-couch (https://ecouch.com.au). In the first week, they will complete the depression information submodule from the depression program. Over the following four weeks, they will complete submodules on behavioral activation and physical activity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-help information based on principles of cognitive restructuring
Description: Participants will engage with the self-help tool e-couch (https://ecouch.com.au). In the first week, they will complete the depression information submodule from the depression program. Over the following four weeks, they will complete submodules on cognitive restructuring.