TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06221189

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACT-CSP
Description: The ACT treatment will consist of three 45 to 60-min weekly sessions to be delivered to the caregiver in an individual format via online videoconferencing application e.g. ZOOM or WhatsApp within 3 weeks. The ACT-CSP can be delivered via face-to-face on request. Each session has a specific content with pre-planned materials and mindfulness exercises and metaphors. Psychological-based homework will be assigned at the end of each session. The components of ACT process will be emphasized in the intervention programme, which include perspective taking, self-as-context and defusion (i.e. recognizing worry thoughts as thoughts only), identifying values and acceptance of present-moment experience with respect to the values, and committed action.
Study: NCT04927754

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral guidance
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. As a result, the effect of the cartoon-assisted distraction technique during dental treatment on behavior in pediatric patients was evaluated.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain assessment
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. It was assessed the effect of the cartoon-assisted audio/visual distraction technique usage on paediatric patient's pain during dental care.
Study: NCT04998617

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Toothpaste without curcumin
Description: Subjects will be given toothpaste to be used during this study without curcumin
Study: NCT06397365

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: medical hypnosis
Description: The first hypnosis session (V2) consists of a safe place suggestion. Through this type of suggestions, patients will safely experience the dissociative state, and will be given tools (recordings of sessions) to perform self-hypnosis at home between the visits. The suggestions will help the patient to visualize an imaginary place where they feel well and safe, a protective place to rest. In this first session, CPAP treatment will be introduced during hypnosis, with specific suggestions relating to the use of this treatment.~The second session (V3) The second session will also use the safe place. We will adapt the suggestions according to the experience reported by the patient on the day of the visit. During this session, we'll focus on changes in the patient's perception of the CPAP machine.~Patients will also be given the recording of each session to perform self-hypnosis at home between the visits.
Study: NCT04927754

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain assessment
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. It was assessed the effect of the cartoon-assisted audio/visual distraction technique usage on paediatric patient's pain during dental care.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dental anxiety assessment
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. It was evaluated the effect of the cartoon-assisted audio/visual distraction technique usage on paediatric patient's dental anxiety during treatment sessions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dental anxiety assessment
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. It was evaluated the effect of the cartoon-assisted audio/visual distraction technique usage on paediatric patient's dental anxiety during treatment sessions.
Study: NCT05861609

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual care with respect to Spinal Cord Stimulation implantation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standardized pain medication tapering
Description: A standardized pain medication tapering program before Spinal Cord Stimulator implantation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Personalized pain medication tapering
Description: A personalized pain medication tapering program before Spinal Cord Stimulator implantation.
Study: NCT05276830

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BXCL501
Description: Sublingual film containing 40 Micrograms BXCL501

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BXCL501
Description: Sublingual film containing 60 Micrograms BXCL501

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo film
Description: Matching Sublingual Placebo film
Study: NCT06448351

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection
Study: NCT05353556

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inspiratory Muscle Training (IMT)
Description: The IMT protocol will consist of home-based high-intensity daily training - two cycles of 30 breaths with a 1-min rest between sets, twice a day for 8 weeks using an IMT Threshold device (Threshold IMT Philips® Respironics, Inc). The intensity of the training will be set to 50% of each patient's maximal inspiratory pressure measured every week and was adjusted weekly based on the modified Borg scale from 4 to 6 regarding respiratory effort performed during the session.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham IMT
Description: The IMT protocol will consist of home-based daily training - two cycles of 30 breaths with a 1-min rest between sets, twice a day for 8 weeks using an IMT Threshold device (Threshold IMT Philips® Respironics, Inc). The intensity of the training will be set to the lowest intensity of the IMT Threshold device.
Study: NCT05346081

Intervention type: DEVICE
Intervention: Electrical impedance tomography
Description: Electrical impedance tomography (EIT) is a potential alternative non-invasive diagnostic screening measure to spirometry.

Intervention type: DEVICE
Intervention: Electrical impedance tomography
Description: Electrical impedance tomography (EIT) is a potential alternative non-invasive diagnostic screening measure to spirometry.
Study: NCT06448351

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection
Study: NCT06318650

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Demineralized Dentin Matrix
Description: preparation of Allogenic Demineralized Dentin Matrix: Extracted teeth will be collected from the Departments of oral maxillofacial surgery and periodontics, Cairo university. Cleaning the teeth from any caries, Filings, cement, tartar, soft tissue debris and prosthetic components will be performed using a diamond bur under abundant irrigation with physiological water. Then it will be proceeded to the following steps~1. (Washing with Distilled water ) 2. (Quick Freezing with liquid nitrogen, then Grinding to particle size of 300- 800 μm). 3.(Ultrasonic Cleaning cycles, 1st with Distilled water , 2nd with 5-7% Hydrogen Perioxide then 3rd with Distilled water for at 60-80 o) 4. (Defatting with Chloroform Methanol Solution1:0.5. 5. (Demineralization with0.5N HCL) 6. (Dehydration with Neutral Ethyl Alcohol then Defatting with Chloroform Methanol Solution 1:0.5 for ) 7. (Washing with Normal Saline \& Freeze Drying then Sterilization using Ethylene oxide gas).

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Demineralized freeze-dried bone allograft (DFDBA)
Description: combination allograft, is a particulate bone graft combining 70% mineralized ground cortical with 30% demineralized ground cortical Particle sizing: 250 - 1000um.
Study: NCT06449079

Intervention type: OTHER
Intervention: Machine learning
Description: Analysis of data with machine learning methods

Intervention type: OTHER
Intervention: Machine learning
Description: Analysis of data with machine learning methods
Study: NCT06448351

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection
Study: NCT05273385

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nanodropper
Description: Device to apply liquid medication to eyes
Study: NCT06448351

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Carbon Monoxide Measurement
Description: Undergo CO test
Study: NCT05634187

Intervention type: DEVICE
Intervention: Functional endoscopy
Description: Transnasal endoscopy by an ultrathin video endoscope
Study: NCT06448351

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Carbon Monoxide Measurement
Description: Undergo CO test
Study: NCT05050617

Intervention type: DIAGNOSTIC_TEST
Intervention: Point-of-care echocardiography
Description: Subjects will undergo point-of-care echocardiography at the time of presentation/enrollment to assess for evidence of right sided heart dilation/strain.
Study: NCT05113225

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Micro-swim up technique
Description: processing and selection of the sperm for ICSI in the same dish

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Micro-swim up technique
Description: processing and selection of the sperm for ICSI in the same dish
Study: NCT05740670

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dr. Kellyann's Bone Broth
Description: Participants will have two bone broth phases, each three weeks in length. Bone broth phases will be separated by a one-week maintenance phase. A one-week maintenance phase will also occur after the second bone broth phase. Each week of a broth phase will consist of five feeding days and five fasting days. On feeding days, participants will consume one packet of bone broth, twice each day, as snacks between meals. On fasting days, participants will consume one packet of bone broth every two hours for a total of seven packets each day.
Study: NCT05494814

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Child Care Centers Served Meals Prepared by Central Kitchen
Description: The child care centers who are served by the central kitchen will receive meals that include locally sourced fresh fruits and vegetables to serve their staff and children.
Study: NCT06120088

Intervention type: DRUG
Intervention: Bubpivacaine
Description: Bupivacaine is a long-acting local anesthetic commonly used to provide pain relief by blocking nerve signals in a specific area. It's often utilized for various medical procedures and surgeries, offering prolonged numbing effects.

Intervention type: DRUG
Intervention: Bubpivacaine
Description: Bupivacaine is a long-acting local anesthetic commonly used to provide pain relief by blocking nerve signals in a specific area. It's often utilized for various medical procedures and surgeries, offering prolonged numbing effects.

Intervention type: DRUG
Intervention: Bubpivacaine
Description: Bupivacaine is a long-acting local anesthetic commonly used to provide pain relief by blocking nerve signals in a specific area. It's often utilized for various medical procedures and surgeries, offering prolonged numbing effects.

Intervention type: DRUG
Intervention: dexamethasone
Description: Dexamethasone is a potent corticosteroid with anti-inflammatory properties. It's frequently employed as an adjunct in medical treatments to reduce inflammation and swelling, and in some cases, to prevent nausea and vomiting associated with certain medications or procedures.

Intervention type: DRUG
Intervention: fentanyl
Description: Fentanyl is a powerful synthetic opioid pain reliever. It acts on the central nervous system to alleviate severe pain. Fentanyl is significantly potent and is used in medical settings for acute pain management, such as during surgeries or for chronic pain in cases where other opioids may not be as effective.
Study: NCT05854056

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conservative rehabilitation protocol
Description: See Arms section
Study: NCT05378906

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRV/COBI FDC
Description: Participants will receive a single oral dose of DRV/COBI FDC tablet dispersed in water as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRV/COBI FDC
Description: Participants will receive a single oral dose of DRV/COBI FDC tablet dispersed in water as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: COBI
Description: Participants will receive a single oral dose of COBI tablet as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: COBI
Description: Participants will receive a single oral dose of COBI tablet as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRV
Description: Participants will receive single oral dose of DRV suspension as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRV
Description: Participants will receive single oral dose of DRV suspension as per the assigned treatment sequence.
Study: NCT06634030

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RhPDGF-BB
Description: 0.3 mg/mL rhPDGF-BB

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Normal saline
Study: NCT06550986

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: False Lumen Embolization System, IMPEDE-FX RapidFill
Description: Embolization of the false lumen of an aortic dissection
Study: NCT06370026

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: KSD-101
Description: Patients will receive approximately 5x10\^6 DC vaccine via subcutaneous injections bi-weekly,total 3-5 times.
Study: NCT04996615

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT04766762

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture combined with placebo
Description: This group will include 48 patients. Patients in this group will receive acupuncture combined with placebo. Participants are in the supine position. The bilateral Tianrong (SI 17) acupoints are needled for 1-1.5 inch with the direction tilted back 45±5 degrees. The bilateral Fengchi (GB 20) acupoints are needled for 0.5-1 inch with the direction tilted to nose. The bilateral Neiguan (PC 6) acupoints are also needled for 0.5-1 inch with the straight direction. In addition, 4-6 additional acupoints can be identified according to different syndrome types of patients. The needles are kept for 30 min, the treatment frequency is 3 times per week, and the treatment duration lasts 8 weeks. Meanwhile, the dosage of placebo is 1 capsule twice a day and the treatment duration also lasts 8 weeks.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Sham acupuncture combined with flunarizine hydrochloride
Description: This group will include 48 patients. Participants in this group will receive sham acupuncture plus flunarizine hydrochloride. Participants are in the supine position and sham acupuncture is conducted. The bilateral Tianrong (SI 17) acupoints, Fengchi (GB 20) acupoints and Neiguan (PC 6) acupoints are selected, and 4-6 additional acupoints can be identified according to the syndrome type of the participants. The needles are kept for 30 min, the treatment frequency is 3 times per week, and the treatment duration lasts 8 weeks. Moreover, the dosage of flunarizine hydrochloride is 5mg twice a day and the treatment duration also lasts 8 weeks.
Study: NCT06130956

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vegan diet
Description: Vegan diet for 2 weeks before surgery

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Omnivorous diet
Description: Omnivorous diet for 2 weeks before surgery
Study: NCT05327387

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: model-based electrical brain stimulation
Description: Electrical pulse train stimulation delivered to medication refractory epilepsy patients with electrodes already implanted based on clinical criteria for standard monitoring unrelated to this study. The delivery of the electrical brain stimulation can be guided by neural biomarkers of symptom levels computed from ongoing neural activity and by input-output models of neural response to stimulation therapy. The parameters of electrical stimulation will be constrained to be within clinically safe ranges.
Study: NCT05402657

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy
Description: UBRUL-FP involves ultrabrief right unilateral ECT delivered using a novel frontoparietal montage, where the anterior electrode is shifted frontally to a position above the midpoint of the right eye to avoid temporal lobe stimulation (and reduce memory side effects). UBRUL-FP will be delivered using standard ECT devices.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy
Description: UBRUL-TP is the standard form of ultrabrief right unilateral ECT, using the conventional temporoparietal (d'Elia) electrode placement, where the anterior electrode is placed over the right temporal lobe. UBRUL-TP will be delivered using standard ECT devices.
Study: NCT06570941

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chylobinoid Topical Cream
Description: The topical cream is applied to the effected area to reduce or eliminate the symptoms of restless leg syndrome
Study: NCT04056533

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CMV CTLs
Description: The donor derived cytomegalovirus specific T lymphocytes (CMV-CTL) will be transfused to the patients. The patients will receive CMV-CTL cells when their donors are sero-positive for CMV-DNA 21 days after transplant. The CMV-DNA levels will be monitored weekly for at least 100 days after the HAPLO. If after the initial dose of CMV-CTL cells the patient develops a viral infection, then they may be eligible to receive a CMV specific antiviral drug.
Study: NCT05967299

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZMA001 (BC-NKA-20008)
Description: ZMA001 is a fully human, monoclonal antibody (IgG1) that inhibits migration of activated monocytes and macrophages and reduces pulmonary vascular remodeling and pulmonary artery pressure in pre-clinical rodent models of pulmonary arterial hypertension (PAH).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 30mg/ml Sucrose