TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05178108

Intervention type: OTHER
Group type: OTHER
Intervention: Real-time MRI of swallowing
Description: The examination recording a total of 9 sequences of less than 30 seconds will be performed, in transverse section (passing through the epiglottis), frontal section, in the plane of the posterior pharyngeal wall, and in median sagittal section.~Each bolus of 20 ml will be administered in full, in one go, using a syringe. It is kept in the mouth for a few seconds and swallowed on demand.~The semi-liquid bolus of 20 ml comes from the mixture of 198 ml of pineapple juice to 10 gr of Nutilis Powder (NUTRICIA), food thickener containing neither gluten, nor lactose.~Ingredients: Dextrin-maltose, thickeners (modified starch (corn), tara gum, xanthan gum, guar gum).~* 3 sequences with no food~* 3 sequences with ingestion of a liquid bolus of 20 ml (pineapple juice) mouth closed~* 3 sequences with ingestion of a semi-liquid bolus of 20 ml (pineapple juice + Nutilis Powder) mouth closed
Study: NCT05871333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan 50mg Tab
Description: Losartan 50 mg oral tablets
Study: NCT06260826

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Auto CPAP via nasal mask (JPAP machine)
Description: Auto Continuous Positive Airway Pressure via nasal mask using the JPAP system (Metran, Saitama, Japan) which can provide CPAP with a range of 2-10 cmH2O, the initial CPAP 2 cmH2O, then reach 7.5 cmH2O after a ramping time. CPAP values may vary with each breath until the obstruction is resolved

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Constant CPAP via facial mask (O2-Max Trio system)
Description: Patients connected to the O2-Max Trio CPAP system (Pulmodyne, Indianapolis, USA) with a facial mask that was adjusted to maintain a CPAP at 7.5 cm H2O and FiO2 30% continuously for the following 1 hour
Study: NCT04936919

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BroadBand Light
Description: Treatment arm will receive Broadband light treatment
Study: NCT06564753

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Drug: Placebo daily and orally
Description: • Placebo comparator

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NA-931, dose 1, daily and orally
Description: Drug: NA-931 dose 1, daily and orally~• NA-931 is a peptide quadruple GLP-1, IGF-1, GIP , Glucagon quadruple agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NA-931, dose2, daily and orally
Description: Drug: NA-931 dose 2, daily and orally~• NA-931 is a peptide quadruple GLP-1, IGF-1, GIP , Glucagon quadruple agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NA-931 dose 3, daily and orally
Description: Drug: NA-931 dose 3, daily and orally~• NA-931 is a peptide quadruple GLP-1, IGF-1, GIP , Glucagon quadruple agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NA-931 dose 4, daily and orally
Description: Drug: NA-931 dose 4, daily and orally~• NA-931 is a peptide quadruple GLP-1, IGF-1, GIP , Glucagon quadruple agonist
Study: NCT03952845

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Capsaicinoid
Description: This is a tolerability study on doses lower than previously published for the use of intranasal capsaicinoid in the treatment of rhinitis
Study: NCT06721754

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Negative Pressure Wound Treatment
Description: Negative Pressure Wound Treatment promotes healing by applying subatmospheric pressure to reduce inflammatory exudate and stimulate granulation tissue.
Study: NCT06759987

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: self-care behavior intervention
Description: The intervention group received the self-care behavior intervention program based on the interaction model of health behavior
Study: NCT06758817

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MedDiet+ intervention
Description: Study arm will consume a Mediterranean like style diet enriched in fermented foods for 12 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: General dietary recommendations
Description: Study arm will be given general healthy eating advice at baseline.
Study: NCT06759675

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: group based exercise with Cognitive functional therapy
Description: 1. Cognitive functional therapy CFT A cognitive functional therapy is the behavioral approach which is used to treat low back pain. This approach has 3 components Making sense of pain Exposure with control Lifestyle changes~2. Group exercises Group exercises will be the exercises that perform on all individuals. It is performed in a group session having 3 components Pain education Exercises Relaxation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group based exercise
Description: Group exercises Group exercises will be the exercises that perform on all individuals. It is performed in a group session having 3 components Pain education Exercises Relaxation
Study: NCT06759584

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: To Compare clinical outcome of dexamethasone phonophoresis in a (continuous and pulsed) maneuver for management of Temporomandibular Disorders
Study: NCT05708014

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention LuvHub
Description: From day 1 to day 487 (i.e., entire 16-month duration, post baseline) of the trial, participants randomized to the intervention arm will have access to use the five modules as directed. The LuvHub intervention includes modules focused on topics of: HIV/STI prevention, sexual agreements, communication/decision-making skills, strengthening relationships and creating goals, and physical activity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Waitlist Control LuvHub
Description: From day 243 to day 487 (i.e., starting after 8-month assessment) of the trial, participants randomized to the waitlist control condition will have access to use the five modules as directed. The LuvHub intervention includes modules focused on topics of: HIV/STI prevention, sexual agreements, communication/decision-making skills, strengthening relationships and creating goals, and physical activity.
Study: NCT06343987

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: 12-week physical activity program with training 3 times a week. The training consists of high-intensity training such as weight-lifting and cardiovascular training, and low-intensity training such as relaxation and stretching.
Study: NCT05019729

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VRC-MALMAB0114-00-AB
Description: VRC-MALMAB0114-00-AB (L9LS) is a monoclonal antibody that binds an epitope of the Plasmodium falciparum circumsporozoite protein.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VRC-MALMAB0114-00-AB
Description: VRC-MALMAB0114-00-AB (L9LS) is a monoclonal antibody that binds an epitope of the Plasmodium falciparum circumsporozoite protein.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VRC-MALMAB0114-00-AB
Description: VRC-MALMAB0114-00-AB (L9LS) is a monoclonal antibody that binds an epitope of the Plasmodium falciparum circumsporozoite protein.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VRC-MALMAB0114-00-AB
Description: VRC-MALMAB0114-00-AB (L9LS) is a monoclonal antibody that binds an epitope of the Plasmodium falciparum circumsporozoite protein.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VRC-MALMAB0114-00-AB
Description: VRC-MALMAB0114-00-AB (L9LS) is a monoclonal antibody that binds an epitope of the Plasmodium falciparum circumsporozoite protein.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plasmodium falciparum (P. falciparum) sporozoite challenge
Description: Participants were exposed to bites on the forearm from mosquitoes infected with Plasmodium falciparum

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plasmodium falciparum (P. falciparum) sporozoite challenge
Description: Participants were exposed to bites on the forearm from mosquitoes infected with Plasmodium falciparum

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plasmodium falciparum (P. falciparum) sporozoite challenge
Description: Participants were exposed to bites on the forearm from mosquitoes infected with Plasmodium falciparum

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plasmodium falciparum (P. falciparum) sporozoite challenge
Description: Participants were exposed to bites on the forearm from mosquitoes infected with Plasmodium falciparum

Intervention type: OTHER
Group type: OTHER
Intervention: Plasmodium falciparum (P. falciparum) sporozoite challenge
Description: Participants were exposed to bites on the forearm from mosquitoes infected with Plasmodium falciparum
Study: NCT06759584

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: To Compare clinical outcome of dexamethasone phonophoresis in a (continuous and pulsed) maneuver for management of Temporomandibular Disorders

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: To Compare clinical outcome of dexamethasone phonophoresis in a (continuous and pulsed) maneuver for management of Temporomandibular Disorders
Study: NCT06182163

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sedentary time intervention
Description: Tests the effect of a multi-component mobile health (mHealth) intervention on reducing sedentary behavior among adolescents and young adults (AYAs) with ALL during maintenance therapy. The intervention includes an app-based peer support group for study participants via WhatsApp, individualized coaching sessions with study staff, and prompts to move delivered via a Fitbit wearable fitness tracker.
Study: NCT06758609

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mechanical thrombectomy
Description: Mechanical thrombectomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical thrombectomy
Description: Mechanical thrombectomy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4°C saline infusion
Description: Patients received a total of 350 ml of 4°C saline infusion in addition to mechanical thrombectomy (MT).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Normothermic saline infusion
Description: Patients received a total of 350 ml of roomtemperature saline infusion in addition to mechanical thrombectomy (MT).
Study: NCT06759285

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental (cradle position)
Description: The newborn in cot bed was swaddled freely with the help of a thin blanket during feeding. Then, the nurse, wearing a box apron, took the baby in her arms and gave it a cradle position. The baby's physiological parameters and Comfort Scale were filled in before feeding began. The baby was kept in a cradle position on the researcher's lap during feeding. Immediately after feeding, without changing the baby's position, the physiological parameters and Comfort Scale were evaluated a second time, and again 15 minutes after feeding, without changing the position, the physiological parameters and Comfort Scale were evaluated a third time and recorded. Then, the baby was gently and slowly laid down on the denim bed as usual (right lateral).
Study: NCT06760208

Intervention type: BIOLOGICAL
Intervention: Pneumococcal 20-valent conjugate vaccine
Description: For intramuscular use only. One dose (0.5 mL) of Pneumococcal 20-valent conjugate vaccine should be administered intramuscularly, preferably in the deltoid muscle, with care to avoid injection into or near nerves and blood vessels.
Study: NCT06759038

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: C-MAC blade D video laryngoscope
Description: C-MAC blade D Video Laryngoscope is used for difficult intubation and for better glottic view

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Macintosh Laryngoscope
Description: Macintosh Laryngoscope is conventional laryngoscope used generally for intubations
Study: NCT05377736

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Molecular analyses
Description: Collect thyroid tissue for molecular analysis from the histological specimen collected by routine surgery
Study: NCT05848674

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CArdiac Brief INtervention (CABIN)
Description: CABIN is designed as a brief intervention with a facilitated discussion between a patient and a nurse, with the provision of a short leaflet that summarises information and acts as an aide memoir. The discussion takes place in a quiet area and is intended to last 15-20 minutes. CABIN involves a nurse listening to the patient and recognising any concerns he / she may have and / or identifying erroneous beliefs. It also provides the patient with personalised education on coronary artery disease and cardiac rehabilitation (i.e., information about stenting, stent placement, medication, and purpose / potential benefits of cardiac rehabilitation), along with facilitating psychological and emotional support discussions with a nurse (i.e., explaining causes of a STEMI, discussing support / treatment options, and exploring methods of improving health).

Intervention type: OTHER
Group type: OTHER
Intervention: Refined version of CABIN
Description: Participants of the control group will receive a refined version of CABIN, which excludes psychological and emotional support discussions with a nurse and details some standard discharge information (information about coronary artery disease and stenting / stent placement).
Study: NCT05852925

Intervention type: OTHER
Group type: OTHER
Intervention: Traditional Venipuncture
Description: Traditional blood collection is performed and the necessary amount of blood is collected into the collection tubes (either SST or Lithium Heparin tubes based on the biomarker being tested).

Intervention type: DEVICE
Group type: OTHER
Intervention: Tasso+
Description: The Tasso+ is the blood self-collection device used in the study and this device enables the collection of microliter capillary whole blood samples into compatible reservoirs. In this study, the reservoirs utilized include either SST or Lithium Heparin microtainers based on the biomarker being tested.
Study: NCT05966766

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mozart selections
Description: Music will be played from a speaker connected to a media-playing device for participants to listen to for set durations of time. Music will be selections by Mozart of previously studied and shown to reduce anxiety.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Patient-preferred music selections
Description: Music will be played from a speaker connected to a media-playing device for participants to listen to for set durations of time. Music will be selections of patient choice.
Study: NCT05223036

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Biopsy
Description: Undergo biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Gastrointestinal Endoscopy
Description: Undergo GI endoscopy

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Gastrointestinal Endoscopy
Description: Undergo GI endoscopy

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Obeticholic Acid
Description: Given PO

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Administration
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT06031350

Intervention type: DIAGNOSTIC_TEST
Intervention: Optical Coherence Tomography Angiography
Description: Optovue, Inc., Fremont, CA, USA

Intervention type: DIAGNOSTIC_TEST
Intervention: Optical Coherence Tomography Angiography
Description: Optovue, Inc., Fremont, CA, USA
Study: NCT06555146

Intervention type: DRUG
Group type: OTHER
Intervention: Semaglutide, 0.5 mg/mL
Description: 1 subcutaneous injection on baseline day

Intervention type: DRUG
Group type: OTHER
Intervention: Semaglutide, 0.5 mg/mL
Description: 1 subcutaneous injection on baseline day

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo, Saline
Description: 1 subcutaneous injection on baseline day

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo, Saline
Description: 1 subcutaneous injection on baseline day
Study: NCT05290142

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Training with Coaching (DT-C)
Description: An identical digital training course and helpline will be available for the participants in this group. In addition to receiving the same digital training resources as the DT group, participants in DT-C will receive weekly individualized telephone calls from a coach who will motivate them and troubleshoot towards course completion. The focus will be on clarifying learning objectives and redirecting participants to relevant materials rather than providing new learning opportunities. Participants will also be able to send text messages to coaches with queries related to course content, progress and technical difficulties. Coaches will reply to participants' messages within one working day and send reminders about upcoming telephone sessions, as well as prompts if the participant has not logged into the course for 3 consecutive days.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self-Guided Digital Training
Description: Participants will be enrolled in a digital training course that addresses non-specific counselling skills and skills specific to an evidence-based problem-solving intervention. The course will be available offline and online on a smartphone app (called 'Sangath Training') as well as a website (https://training.sangath.in/login/index.php) that can be accessed through an internet-enabled device. The training will be delivered through didactic lectures, role-play demonstrations, and recommended readings spread across 16 modules. Participants will be provided with automated feedback on their learning through self-assessment quizzes after each module. Modules will be available sequentially and unlocked after accessing all content in the preceding module, over a period of 4 weeks. Technical helpline: Participants will also have an option to message a centralized helpline for assistance with accessing and navigating the digital interface.
Study: NCT04825236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MyVoice:CF
Description: Participants will be given access to MyVoice:CF, a web-based decision aid (DA). This tool includes information about fertility, genetics, parenting, pregnancy, and breastfeeding within the context of cystic fibrosis (CF). The tool includes interactive elements designed to give users the ability to assess and reflect on their own reproductive goals and experiences and promote self-efficacy to engage in shared decision-making with their CF and women's health providers.~Upon completion of use of the decision aid, a summary sheet is generated based on the user's interaction with the tool. This summary is supplied to the provider prior to the next appointment.
Study: NCT06461780

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Line-based questionnaire follow-up
Description: The participant will use LINE group to report irAE severity, distress, financial toxicity and change trajectory of quality of life in one-year follow-up. If the severity grade of irAE reach the threshold and require referral, an alarm will appear to notify the research team to conduct and transfer to a clinical specialitst, or refer to the emergency room for treatment. Additionally, the Line group will also provide clinical relevant immunotherapy health education information currently and routinely used in study site. Patients can view it according to their interests, but the APP will not actively promote it.
Study: NCT06426303

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone
Description: 12-week randomized double blinded placebo-controlled drug trial titrating drug/placebo dose after 1 week.
Study: NCT06527612

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary rehabilitation exercise programme
Description: In addition to standard medical treatment, the EGr will undergo an exercise program. The initial exercise training will be conducted in the hospital, followed by online exercise sessions via video conferencing three times a week during the first week. From the second week onwards, they will be asked to perform their exercises at home three times a week using provided exercise videos and will be monitored for one year. Compliance with the exercise regimen will be assessed through a weekly survey shared in a WhatsApp group established for the exercise group patients.
Study: NCT06266858

Intervention type: OTHER
Group type: OTHER
Intervention: rehydration
Description: The fasting patients in anaesthetised receive saline rehydration to maintain central venous pressure of 6-8 cmH2O when undergoing UCG.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: UCG
Description: UCG is the most common imaging modality to assess the mitral regurgitation in clinical and also is the primary modality recommended by guidelines. At the beginning of the study, the fasting patients receive UCG in the different situation such as pre-anaesthetic, post-anaesthetic and post-rehydration.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: UCG
Description: UCG is the most common imaging modality to assess the mitral regurgitation in clinical and also is the primary modality recommended by guidelines. At the beginning of the study, the fasting patients receive UCG in the different situation such as pre-anaesthetic, post-anaesthetic and post-rehydration.
Study: NCT05897346

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 'Learning while serving' training program
Description: The training program will involve training workshops, hands-on sessions, and a smoker referral competition.

Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: A 3-hour training workshops in the control group are regarded as usual care since the training workshops are also conducted regularly to other secondary or tertiary schools.
Study: NCT05162248

Intervention type: DIAGNOSTIC_TEST
Intervention: Microsatellite instability analysis
Description: Molecular analysis for Microsatellite Instability (MSI) status was performed using immunohistochemistry (IHC). IHC now recognized as an approved method to highly precision predict MSI in colorectal cancer.
Study: NCT05111899

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Newborn Health Education
Description: Community influencers will receive training and give community education to women and their families regarding newborn health.