TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06761807

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electrophysiology study of heart
Description: The procedure will be done comparatively for each patient; before the device placement and immediately after the procedure.~This will be done approaching the same sheath that is placed for ASD device closure (the right femoral vein).~Only one quadripolar EP catheter will be used, it will be placed in high right atrium then at His bundle.~The EP study will include:~Assessment of SAN function using cSNRT (through HRA pacing) Assessment of AH and HV intervals (through His bundle EGM) Assessment of antegrade AVN RP (refractory period) and AVN WP (Wenckebach point) through extra-stimuli and incremental atrial pacing.~Any inducible arrhythmia will be reported
Study: NCT06021158

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Hybrid automated Lyumjev delivery system with carbohydrate counting
Description: In this system, a Lyumjev insulin bolus is initiated at mealtime based on the total grams of carbohydrates counted. This is the same as commercial hybrid closed-loop insulin therapy (standard treatment).

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Hybrid automated Lyumjev delivery system with meal size estimation
Description: In this system, a Lyumjev insulin bolus is initiated at mealtime based on the qualitative amount of carbohydrates estimated (e.g., low-carb meal).

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Fully automated Lyumjev delivery system with meal detection
Description: In this system, the patient does not initiate a Lyumjev insulin bolus at mealtime. An algorithm is used to detect a meal and administer a subsequent bolus, rather than requiring a carbohydrate count.
Study: NCT04652869

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: Mindfulness is a type of meditation in which you focus on being intensely aware of what you're sensing and feeling in the moment, without interpretation or judgment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: Mindfulness is a type of meditation in which you focus on being intensely aware of what you're sensing and feeling in the moment, without interpretation or judgment.
Study: NCT05757154

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet
Description: All intervention arms are coffee. Three different types of coffee is tested. Differences in type of bean, degree of roasting and preparation method.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet
Description: All intervention arms are coffee. Three different types of coffee is tested. Differences in type of bean, degree of roasting and preparation method.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet
Description: All intervention arms are coffee. Three different types of coffee is tested. Differences in type of bean, degree of roasting and preparation method.
Study: NCT05343130

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Brain-Computer Interface
Description: Hand movement will be elicited using functional electrical stimulation activated by the brain-computer interface based on hand movement intention.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Brain-Computer Interface
Description: Hand movement will be elicited using functional electrical stimulation which activation will be independent of the brain-computer interface based on hand movement intention.
Study: NCT06326788

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Short Duration Moderate Intensity Soleus Push-ups
Description: Participants will start soleus pushups in sitting positions. To do so, the participants will be in a seated position, the legs will be at 90 degrees to the floor, and the feet will be placed flat on the ground.~Participants will then move their heels up and down continuously. Soleus push-ups will be performed with moderate intensity using weights which will be placed on their laps.~Participants will perform this activity till 60-70% of their maximum heart rate is achieved and maintained.
Study: NCT06036160

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated care
Description: Psychiatric follow-up, cognitive behavioral therapy, physical exercise, psychoeducation
Study: NCT06326788

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SUSTAINED SOLEUS PUSH-UPS
Description: Participants will start soles push-ups in sitting. To do so, the participants will be in a seated position, the legs will be at 90 degrees to the floor, and the feet will be placed flat on the ground.~Participants will then move their heels up and down continuously. Sustained soleus push-ups will be performed with light intensity for up to 270 mins.~No external resistance will be added. Participants will be provided with a maximum 4-minute break time after every 90 mins intervention. In the meantime, their blood sample will be collected.
Study: NCT05902936

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpotomy for mature permanent mandibular molars
Description: Performing pulpotomy for mature teeth that involves removal of the coronal pulp tissue that is diseased or inflammed followed by placement of a biocompatible material with the intent of maintaining the vitality of the remaining radicular pulp tissue.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulpotomy for mature permanent mandibular molars
Description: Performing pulpotomy for mature teeth that involves removal of the coronal pulp tissue that is diseased or inflammed followed by placement of a biocompatible material with the intent of maintaining the vitality of the remaining radicular pulp tissue.
Study: NCT06509165

Intervention type: PROCEDURE
Intervention: Modified coronally advanced flap technique
Description: Subepithelial connective tissue graft was applied to the relevant areas with a modified coronally placed flap technique to cover the gingival recession.

Intervention type: PROCEDURE
Intervention: Tunnel technique
Description: Subepithelial connective tissue graft was applied to the relevant areas with the tunnel technique to cover the gingival recession.
Study: NCT04727294

Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Series of questions covering COVID-19 diagnosis and treatment, changes in myeloma treatment and care, clinical trial familiarity, health and fitness, and quality of life.
Study: NCT05075499

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 vaccination
Description: Blood sample obtained before, 1 , 3 and 6 months after the intervention
Study: NCT05083546

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gly-low
Description: MGO cocktail containing a combination of alpha-lipoic acid, nicotinamide, thiamine, pyridoxamine, and piperine

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: sugar pill
Study: NCT06415981

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hypoglossal nerve and/or Ansa Cervicalis stimulation
Description: Device stimulation of the hypoglossal nerve and/or Ansa Cervicalis
Study: NCT05370963

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hylase versus dexmedtemodine
Description: fluroscopic guided lumber epidural injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hylase versus dexmedtemodine
Description: fluroscopic guided lumber epidural injection
Study: NCT05879770

Intervention type: OTHER
Intervention: suture material
Description: Some patients have had a shouldice repair with wire in the past and others with Prolene.

Intervention type: OTHER
Intervention: suture material
Description: Some patients have had a shouldice repair with wire in the past and others with Prolene.
Study: NCT05075499

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 vaccination
Description: Blood sample obtained before, 1 , 3 and 6 months after the intervention

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 vaccination
Description: Blood sample obtained before, 1 , 3 and 6 months after the intervention
Study: NCT05159492

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PVI using PEF
Description: PVI using PEF

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PVI using CFRF
Description: PVI using CFRF
Study: NCT04269577

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SSP training
Description: Participants will practice the Swipe Slide Pattern (SSP) task. On day 1, participants perform two runs of the SSP-task (only one pattern), each lasting approx. 10 min, within an MR scanner. During each run, nine trials of 30s are performed, alternated with rest periods of 14s. In addition, instructions are provided before each trial (i.e. view of the pattern, 4s), as well as an answer option (i.e. participants have circle a random number from zero to nine, 6s). For the following four days (day 2-5), participants will continue practice of the SSP-task at home. During the at-home-sessions, participants will perform nine trials of 12 patterns each, alternated with rest periods of 14s. Instruction are also included. During at home practice, the same pattern as during scans is included, in combination with two new patterns.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SSP training
Description: Participants will practice the Swipe Slide Pattern (SSP) task. On day 1, participants perform two runs of the SSP-task (only one pattern), each lasting approx. 10 min, within an MR scanner. During each run, nine trials of 30s are performed, alternated with rest periods of 14s. In addition, instructions are provided before each trial (i.e. view of the pattern, 4s), as well as an answer option (i.e. participants have circle a random number from zero to nine, 6s). For the following four days (day 2-5), participants will continue practice of the SSP-task at home. During the at-home-sessions, participants will perform nine trials of 12 patterns each, alternated with rest periods of 14s. Instruction are also included. During at home practice, the same pattern as during scans is included, in combination with two new patterns.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SSP training
Description: Participants will practice the Swipe Slide Pattern (SSP) task. On day 1, participants perform two runs of the SSP-task (only one pattern), each lasting approx. 10 min, within an MR scanner. During each run, nine trials of 30s are performed, alternated with rest periods of 14s. In addition, instructions are provided before each trial (i.e. view of the pattern, 4s), as well as an answer option (i.e. participants have circle a random number from zero to nine, 6s). For the following four days (day 2-5), participants will continue practice of the SSP-task at home. During the at-home-sessions, participants will perform nine trials of 12 patterns each, alternated with rest periods of 14s. Instruction are also included. During at home practice, the same pattern as during scans is included, in combination with two new patterns.
Study: NCT05019742

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPH3127
Description: SPH3127 - selective renin inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPH3127
Description: SPH3127 - selective renin inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo
Study: NCT05801757

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam
Description: Using two different doses of remidazolam for continuous pumping to maintain anesthetic effect

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam
Description: Using two different doses of remidazolam for continuous pumping to maintain anesthetic effect

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: propofol 2-3mg/kg/h
Study: NCT04867850

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Individual clinicians will receive an automated weekly email detailing a weekly roster of their upcoming repeat-patient visits (Index Visit) with patients at high risk of 6-month mortality as determined by a validated machine learning prognostic algorithm. Clinicians will receive a HIPAA compliant text message on the morning of the appointment reminding them to consider a serious illness conversation with patients on the list.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinician Nudge
Description: Clinicians will receive the usual care weekly email and text message described above under Usual Care. In addition, embedded in the weekly email, clinicians will receive performance feedback information detailing their documented SICs relative to those documented by peers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinician Nudge
Description: Clinicians will receive the usual care weekly email and text message described above under Usual Care. In addition, embedded in the weekly email, clinicians will receive performance feedback information detailing their documented SICs relative to those documented by peers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient Nudge
Description: Ahead of the Index Visit, high risk patients as identified by the prognostic algorithm will receive a nudge via personal text message and email consisting of a normalizing message prompting patients with a personalized link to a short electronic questionnaire on SIC topics.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient Nudge
Description: Ahead of the Index Visit, high risk patients as identified by the prognostic algorithm will receive a nudge via personal text message and email consisting of a normalizing message prompting patients with a personalized link to a short electronic questionnaire on SIC topics.
Study: NCT05357677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR419
Description: SR419 capsule
Study: NCT05971485

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin 10 mg
Description: Melatonin 10 mg will be used. 5 mg·kg-1 dissolved in 2 ml of distilled water via enteral route in one single dose 30 minutes before the venous cannula insertion

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo group will receive 2 ml of distilled water as a placebo 30 minutes before venous cannula insertion.
Study: NCT06329427

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dragon Ambient eXperience (DAX) Copilot
Description: The tool (DAX) listens to the conversation between a clinician and patient/caregiver during their visit, provides transcriptions between different speakers for the clinician to review, edit, and included in the final EHR notes.
Study: NCT04834154

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness
Description: 6 weekly 2.0 hour video-conferenced group sessions with the following components: 1) short grounding meditation, 2) check in/review of prior weeks practice and symptoms, 3) educational topic, 3) main meditation, 4) reflection on meditation, and 5) action plan formation

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: Wait list control
Study: NCT04765423

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: [F-18] NaF PET/CT
Description: Radiotracer F-18 NaF used on the PET/CT imaging

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: [F-18] fluciclovine PET/CT
Description: F-18 fluciclovine (Axumin ®) used on the PET/CT camera
Study: NCT03587831

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vertical Sleeve Gastrectomy
Description: Surgical Procedure: Vertical Sleeve Gastrectomy

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle Modification Counseling
Description: Behavioral Intervention: Lifestyle Modification Counseling

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Modification Counseling
Description: Behavioral Intervention: Lifestyle Modification Counseling
Study: NCT05980364

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Technology-based training structured according to the Health Promotion Model
Description: Experimental group: A video recording was created with a total of 6 zoom applications to be shared with the patients. The content of the video recordings consists of a presentation accompanied by a slide show with open-ended questions prepared by considering the basic concepts of the trainings and the Health Promotion Model. Video recordings, each of which lasted approximately 15-25 minutes, were shared with patients once a week for a total of 6 weeks via WhatsApp. After each video, patients were given three days to watch the video recordings and create their own responses. After this three-day period, the researcher called the patients with whom he shared the content and gave counseling for 10-15 minutes and received feedback. Follow-up was done in the second 6-week period. During the monitoring process, two reminder interviews were made over the phone, with an interval of 2 weeks, for reminder and counseling, and the post-test data were collected at the end of the monitoring period.
Study: NCT06357871

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05764304

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sinomenine
Description: Participants will receive one intra-articular injection every 4 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glucocorticoid
Description: Participants will receive one intra-articular injection every 4 months
Study: NCT04480190

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: IV Gemcitabine 1000mg/m2 to be given on Days 1, Day 8 (Before Cisplatin); 3 week cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV Cisplatin 25mg/m2 to be given on Days 1, Day 8

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Infusional 5-FU 225 mg/m2/d via Continuous IV infusion, to be given Days 1-5 and 8-12 during RT

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Short course ChemoRT
Description: Radiation Therapy:~Sim: All patients will undergo 4D-CT simulation with 3 hours fasting with or without IV contrast. Compression may be used depending on the tumor motion.~Radiation Target Volume: The gross tumor volume (GTV) will be defined on all relevant imaging datasets including diagnostic CT, MRI, MRCP and/or ERCP data. An iGTV will be generated using the 4D datasets. The clinical target volume (CTV) will include the entire iGTV as well as portal lymphatic and celiac nodal space for all patients with selective treatment of the SMA and pancreaticoduodenal depending on the tumor location. A 5 mm margin will be added to the CTV to generate the planning target volume (PTV).~Radiation Dose: The dose will be 30 Gy in 10 fractions (3 Gy per fraction) for all patients using either 3D Conformal or Intensity Modulated Radiation Therapy techniques.
Study: NCT04732130

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Time-Restricted Feeding
Description: Participants are instructed to limit food intake to maximum 8 hours per day.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Alternate Day Fasting
Description: Participants are instructed to fast every other day.
Study: NCT05041595

Intervention type: DIAGNOSTIC_TEST
Intervention: Lyme diagnostic assay
Description: Serological and immunoresponse assay

Intervention type: DIAGNOSTIC_TEST
Intervention: Lyme diagnostic assay
Description: Serological and immunoresponse assay
Study: NCT06089213

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: real-time intervention
Description: An individual exercise program will be carried out at home, supervised remotely via videoconference.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: real-time intervention
Description: An individual exercise program will be carried out at home, supervised remotely via videoconference.
Study: NCT05077995

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polar M200
Description: Participants will have to wear the activity monitors (AP and Polar M200) for at least 7 days. Minutes spent in each activity type will be summed to a total day score. Participants will be instructed to do their regular daily life activities without limitation, but to note their main activity categories in an activity diary, with a main focus on cycling and participation in structured exercise.
Study: NCT05105282

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Two different blocks with same local anesthetic volume
Description: Deep serratus anterior block and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Two different blocks with same local anesthetic volume
Description: Deep serratus anterior block and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.
Study: NCT05848700

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SEP-363856
Description: SEP-363856 Tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo Tablet