Study: NCT05236231

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg
Description: Macitentan 10mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg
Description: Macitentan 10mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg
Description: Macitentan 10mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg
Description: Macitentan 10mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg
Description: Macitentan 10mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg
Description: Macitentan 10mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil 20 mg
Description: Tadalafil 20mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil 20 mg
Description: Tadalafil 20mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil 20 mg
Description: Tadalafil 20mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil 20 mg
Description: Tadalafil 20mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil 20 mg
Description: Tadalafil 20mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil 20 mg
Description: Tadalafil 20mg tablet will be administered orally as per assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg/Tadalafil 20mg FDC
Description: FDC of Macitentan 10 mg/Tadalafil 20 mg will be administered orally as single dose tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg/Tadalafil 20mg FDC
Description: FDC of Macitentan 10 mg/Tadalafil 20 mg will be administered orally as single dose tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg/Tadalafil 20mg FDC
Description: FDC of Macitentan 10 mg/Tadalafil 20 mg will be administered orally as single dose tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg/Tadalafil 20mg FDC
Description: FDC of Macitentan 10 mg/Tadalafil 20 mg will be administered orally as single dose tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg/Tadalafil 20mg FDC
Description: FDC of Macitentan 10 mg/Tadalafil 20 mg will be administered orally as single dose tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan 10 mg/Tadalafil 20mg FDC
Description: FDC of Macitentan 10 mg/Tadalafil 20 mg will be administered orally as single dose tablets.