TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05644171

Intervention type: DEVICE
Group type: OTHER
Intervention: RESToration Of Rehabilitative function with Epidural spinal Stimulation
Description: Three patients with chronic motor SCI will be recruited in total for this study. The recruited patients will not be randomized nor blinded due to the nature of this study. Pre-op rehabilitation session will take place over 4 weeks. 1 month post-surgical implants, patients will undergo 24 weeks of rehabilitation. The training sessions may continue to take place after the stipulated 24 weeks as long the electrode remains implanted, and the patient is available.
Study: NCT05699174

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care PO (oral) antibiotics
Description: An intervention in this study includes randomization of patients with an infected nonunion to PO (oral) antibiotics for up to 6 weeks post hospitalization. The exact type of oral antibiotic will be depended on the patient's infection diagnosis.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Intravenous (IV) antibiotics
Description: An intervention in this study includes randomization of patients with an infected nonunion to intravenous (IV) antibiotics for up to 6 weeks post hospitalization. The exact type of IV antibiotic will be depended on the patient's infection diagnosis.
Study: NCT06387680

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Effect of Peanut Ball Use on Labor Memory, Labor Satisfaction, Delivery Length, and Neonatal APGAR Score: A Randomized Controlled Trial
Description: The Effect of Peanut Ball Use on Labor Memory, Labor Satisfaction, Delivery Length, and Neonatal APGAR Score: A Randomized Controlled Trial
Study: NCT01297400

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Investigational Drug, MW-III
Description: Topical application, twice a day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Silvadene® Cream 1% [Silver Sulfadiazine]
Description: Topical application, twice a day
Study: NCT04428606

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Metabolic Rheostat
Description: Metabolic Rheostat™ Ingredients: Ginseng extract, Ginseng root extract, berberine chloride, Livaux (gold kiwi powder), MegaSporeBiotic, and MenaquinGold (vitamin K2-7) powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Butyrate Ultra
Description: An anerobic probiotic supplement that contains butyrate-producing Butyricicoccus pullicaecorum 25-3T, vitamin K2, and fenugreek to maintain healthy glucose balance.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06318533

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: anti-CD19 CAR NK cells
Description: Patients will receive Fludarabine (30mg/m2 per day) and Cyclophosphamide (300mg/m2 per day) on day -5, -4, and -3, followed by Anti-CD19 CAR NK cells infusion.
Study: NCT06030843

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 10 MG
Description: Empagliflozin 10 MG

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo containing Lactose content (0.26 gram)
Study: NCT06233526

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chemotherapy regiments based on the transcriptomic profile and in vitro drug sensitivity test
Description: 1. Leukemia cells from newly diagnosed and relapsed children with AML were tested for high throughput in vitro drug sensitivity and resistance.~2. Combined with multi-omics sequencing technology such as whole exome and transcriptome, the data of drug sensitivity, drug resistance and genomic characteristics of children AML patients were integrated, and the internal rules between drug sensitivity or drug resistance and molecular characteristics such as gene fusion, gene mutation and abnormal gene expression of children AML patients were deeply analyzed, and the molecular characteristics of drug sensitivity in children AML were mapped
Study: NCT05490420

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: manual lymphatic drainage (MLD)
Description: MLD is a manual technique that is applied to the lymphatic system with a pressure of approximately 40-50mmHg and increases the working speed of lymphatic nodules/collectors. Its main purpose is to support microcirculation by accelerating lymphatic flow and to prevent/remove interstitial fluid accumulation that may cause fascial adhesions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: manual lymphatic drainage (MLD)
Description: MLD is a manual technique that is applied to the lymphatic system with a pressure of approximately 40-50mmHg and increases the working speed of lymphatic nodules/collectors. Its main purpose is to support microcirculation by accelerating lymphatic flow and to prevent/remove interstitial fluid accumulation that may cause fascial adhesions.
Study: NCT04506294

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: eScreen system
Description: The eScreen system is composed of a child screening component and a parent information component. The child screening component is delivered via a game-like interface and includes assessment of current pain, PTSS, and functional recovery. Children are asked to play the game at least 3x/week. The parent information component consists of text / email messages sent to parents at least weekly that summarize child ratings and include a link to an online dashboard with additional personalized information for parents.
Study: NCT06084130

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zolpidem
Description: 10 milligrams zolpidem contained in white-color opaque medicine capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: corn-starch contained in identical white-color opaque medicine capsule
Study: NCT06483880

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Albendazole
Description: Patients will receive albendazole therapy at the recommended dosage.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive the placebo, which will be starch tablets in the same dosage of albendazole.
Study: NCT06388473

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tailored implementation intervention
Description: The tailored implementation intervention comprised of six implementation strategies: 1) Involve executive boards, 2) Mandate change, 3) Provide education and training, 4) Identify and prepare champions, 5) The use of information and communication technology and 6) Audit and provide feedback.
Study: NCT05506397

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupressure
Description: Acupressure is a technique based on stimulating certain points on the body with stimulation methods such as hands and fingers.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Acupressure
Description: Acupressure is a technique based on stimulating certain points on the body with stimulation methods such as hands and fingers.
Study: NCT04957290

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NOX66
Description: NOX66 800 mg daily (400 mg suppository twice daily \[BID\]).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NOX66
Description: NOX66 1200 mg daily (600 mg suppository BID).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NOX66
Description: NOX66 1600 mg daily (800 mg suppository BID).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NOX66
Description: NOX66 2400 mg daily (1200 mg suppository BID).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NOX66
Description: NOX66 RP2D

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NOX66
Description: NOX66 RP2D

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: EBRT
Description: The dose levels of EBRT will be either 8 Gy as a single fraction, or 20/25 Gy as 5 fractions given over 5 to 10 days.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: EBRT
Description: The dose levels of EBRT will be either 8 Gy as a single fraction, or 20/25 Gy as 5 fractions given over 5 to 10 days.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: EBRT
Description: The dose levels of EBRT will be either 8 Gy as a single fraction, or 20/25 Gy as 5 fractions given over 5 to 10 days.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: EBRT
Description: The dose levels of EBRT will be either 8 Gy as a single fraction, or 20/25 Gy as 5 fractions given over 5 to 10 days.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: EBRT
Description: The dose levels of EBRT will be either 8 Gy as a single fraction, or 20/25 Gy as 5 fractions given over 5 to 10 days.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: EBRT
Description: The dose levels of EBRT will be either 8 Gy as a single fraction, or 20/25 Gy as 5 fractions given over 5 to 10 days.
Study: NCT04780542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yo Puedo Sentirme Bien- Clinician-Guided version
Description: Internet delivered Cognitive Behavioral Therapy- Guided version

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Yo Puedo Sentirme Bien- Self-Guided version
Description: Internet delivered Cognitive Behavioral Therapy- Self-Guided version
Study: NCT05399316

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Inulin
Description: Natural fiber supplement extracted from chicory

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Natural non-fermentable sugar
Study: NCT05227339

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RAE
Description: Subjects in the interventional group will have access to the RAE Health mobile app which receives continuous physiologic data from a wearable device. Algorithms embedded in the RAE app detect stress and craving events, and trigger mobile phone notifications when detected. Notifications are paired to real-time mindfulness based interventions.
Study: NCT05589285

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Injection of autologous whole blood to the plantar fascia
Description: Patients assigned in this group will have 2 ml of blood withdrawn from a peripheral vein, then mixed with 1 mL Lidocaine 2% for a total of 3mL volume in one syringe. The patient will be asked to lie down in the clinic bed, and the injection will be administered to the plantar fascia by the principal investigator using a sterile technique.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Injection of normal saline to the plantar fascia
Description: This will be the control group receiving sham injection. Patients will have 2 ml of blood withdrawn from a peripheral vein for blinding proposes. They will be asked to lie down on the clinic bed, 1 ml of normal saline will be administered under sterile technique by the principal investigator. The blood that was withdrawn initially will be discarded.
Study: NCT05345925

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Moderato
Description: Several algorithms comprising CNT will be delivered by the Moderato Implantable Pulse Generator. Each application will last approximately 3 min with 2 minutes baseline (regular pacing) between them. Hence, each subject will serve as its own control (during pacing) and test (during CNT application). Furthermore, the average control value for the whole group will be compared with the average test values of CNT algorithms at the different ventricular lead locations for efficacy assessments. Stratification of subjects by initial hemodynamic parameters (such as Ejection Fraction, for example) would be possible depending on the total number of subjects in each group.
Study: NCT05597293

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Glucose monitoring using FreeStyle Libre 2
Description: Glucose monitoring in patients with type 2 diabetes using FreeStyle Libre 2

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Glucose monitoring using FreeStyle Libre pro iQ
Description: Glucose monitoring in patients with type 2 diabetes using FreeStyle Libre pro iQ
Study: NCT05449704

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5218
Description: single dose administration (DA-5218 one tablet once a day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5218
Description: single dose administration (DA-5218 one tablet once a day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5218-R1 + DA-5218-R2 + DA-5218-R3
Description: single dose administration (DA-5218-R1 one tablet once a day + DA-5218-R2 one tablet once a day + DA-5218-R3 one tablet once a day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5218-R1 + DA-5218-R2 + DA-5218-R3
Description: single dose administration (DA-5218-R1 one tablet once a day + DA-5218-R2 one tablet once a day + DA-5218-R3 one tablet once a day)
Study: NCT05249478

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine and fentanyl
Description: bupivacaine and fentanyl will be infused through the catheter

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine and fentanyl
Description: bupivacaine and fentanyl will be infused through the catheter

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine and fentanyl
Description: bupivacaine and fentanyl will be infused through the catheter
Study: NCT05019118

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental milk
Description: UNICLA milk naturally enriched in selenium and omega-3.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental yogur
Description: UNICLA yogur naturally enriched in selenium and omega-3.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental fresh cheese
Description: UNICLA fresh cheese naturally enriched in selenium and omega-3.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo milk
Description: Conventional milk

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo yogur
Description: Conventional yogur

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo fresh cheese
Description: Conventional fresh cheese
Study: NCT06304467

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contingency Management
Description: Study subjects who have received a liver transplant and have been randomized to the treatment arm will receive contingency management, a positive reinforcement behavioral treatment with escalating rewards for consecutive either negative urine and blood tests (or lower value of metabolites than the previous week for PeTH) depending on which results are received first, capped at a maximum of $80 (in the form of a gift card) at the week 10 visit.
Study: NCT05922800

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electro Press Needle
Description: Body acupoints will be stimulated by the press needles 0.25mm in diameter and 2mm in length and ear acupoints will be stimulated by the press needles 0.25mm in diameter and 0.9mm in length (all from ZhenXing Brand, Hangzhou Yuanli Medical Appliance Factory, China). After sterilization of the local skin, the needle will be pressed to the acupoints and the tape will be sticked to the skin. Then, the electric device (φ44×15.8mm Type ZXHPAMDZB-02C) together with the electrode patch will be sticked to the surface of skin (on top of the sticky tapes of the press needle) in the area of CV4 and bilateral EX-CA1, and bilateral SP6 respectively. The electric device will be switch to the mode of dense intermittent wave, and the current intensity will be increased gradually till the muscles around jumps slightly.All the needles on the body acupoints will be removed after each session, while those on the auricular acupoints can be kept for as long as 6 hours (removed before going to bed).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gamma-Oryzanol
Description: The patients in this group were given orally gamma-oryzanol tablets 20mg each time, three times a day, for 6 months.
Study: NCT04420936

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MAINTAIN PRIME Lifestyle Coaching
Description: Participants will receive two years patient support consisting of supportive coaching via EHR patient portal and tracking tools with EHR. Participants will also receive primary care physician (PCP) support with real time progress reports with counseling tips via EHR prior to visits, notification of weight changes greater or equal to 10 pounds, and annual PCP feedback.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control tracking
Description: Participants will receive two years of patient support consisting of prevention updates via EHR patient portal and tracking tools within the EHR. Participants in this group will not receive primary care physician (PCP) support.
Study: NCT05082597

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low energy ESWT
Description: Therapeutic sessions: 4(once a week, for 4 weeks) Total dosage: 2500 shoots over axillary cord lesion (1000 over most fibrotic area, 500 over upper arm, 500 over forearm, 500 over other area) Energy: 0.056-0.065mJ/mm2
Study: NCT05864092

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Goggles
Description: We will offer patients virtual reality goggles with guided meditation software in addition to standard medical therapy (NSAID and opioid).
Study: NCT05744245

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swallow Strength and Skill Training
Description: Practice swallowing exercises with biofeedback and strength and skill targets

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swallow Strength and Skill Training
Description: Practice swallowing exercises with biofeedback and strength and skill targets
Study: NCT04960839

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Prophylactic contralateral breast irradiation
Description: The whole contralateral breast will be irradiated once daily, 5 days a week, for 5-6 weeks, using 1.8-2 Gy/fx to a total dose of 45-50 Gy.
Study: NCT05066542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NDPP + Basketball (BB)
Description: DPP Hoops: Participants in this arm will participate in the traditional NDPP program delivered virtually by certified NDPP coaches along with virtual fitness sessions and in-person basketball sessions. During Months 1-4, participants will attend a 60-minute virtually facilitated session of the NDPP curriculum, followed by a 30- minute virtual fitness session. During that same week, participants will meet in person, for a 90-minute BB session. During Months 5-8, virtual NDPP curriculum sessions will be held every two weeks and there will no longer be a 30-minute online fitness session succeeding the session. During this same four-month period, 60-minute, in-person BB sessions will be held weekly. During Months 9-12, participants will attend a monthly 60-minute NDPP curriculum session and biweekly 60-minute in-person BB sessions. Participants will submit a weekly weight report during the 12 month participation and will complete the ASA 24 hour food recall every 90 days.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: NDPP Standard of Care SOC
Description: DPP: Participants in this arm will participate in the traditional NDPP program delivered virtually by certified NDPP coaches. During Months 1-4 participants will attend a 60-minute virtually facilitated session of the NDPP curriculum. During Months 5-8, virtual NDPP curriculum sessions will be held every two weeks. During Months 9-12, participants will attend a monthly 60-minute NDPP curriculum session. Participants will submit a weekly weight report during the 12 month participation and will complete the ASA 24 hour food recall every 90 days.
Study: NCT06131099

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dohsa hou exercises
Description: Dohsa hou is a type of psychomotor therapy that helps improve psychological problems by using bodily movements, sensation and relaxation experience.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard treatment protocal
Description: Standard treatment including soft tissue massage therapy, task specific training interventions, bicycle training and aerobic exercises.
Study: NCT06337019

Intervention type: OTHER
Intervention: Cohort observational
Description: Cohort observational
Study: NCT05501119

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A Program of SUPPORT-D (dementia)
Description: The SUPPORT-D intervention consists educational materials will be presented in a format with enhanced content (face-to-face virtually delivered by nurse interventionist via telehealth (e.g., MS Teams), with printed booklet, and identical digital content (electronic pdf and recorded videos of printed content). The SUPPORT-D intervention will be addressed in four sequential sections including: 1) understanding the disease 2) caring for myself; 3) information for the caregiver; and 4) planning for the future. Within the four sections of the intervention seven topics are addressed included symptom management, understanding your disease, putting safety first, ongoing conversations, respite care, palliative care, and alternative treatments. Participants will attend a total of 4 study visits across 8 weeks (approximately every 2 weeks).
Study: NCT06162208

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard exercise program based on telerehabilitation
Description: Exercises included in a standard exercise program based on telerehabilitation; Week 0-3 Patellar mobilization Isometric quadriceps femoris exercise Terminal extension exercise Active assisted knee flexion Straight leg lift Active hip abduction Active assisted knee flexion in sitting SAFTE Cold pack application Week 3-6 Straight leg raises with weights Hip abduction in weighted side lying Knee flexion in the prone position Knee extension in weight-bearing sitting Sliding forward in the chair to increase the knee flexion angle Standing weighted hip abduction Standing knee flexion with weight Squat Walking Climbing stairs Action observation therapy will be practiced by watching videos of all exercises with a focus on close-up action.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard exercise program based on telerehabilitation
Description: Exercises included in a standard exercise program based on telerehabilitation; Week 0-3 Patellar mobilization Isometric quadriceps femoris exercise Terminal extension exercise Active assisted knee flexion Straight leg lift Active hip abduction Active assisted knee flexion in sitting SAFTE Cold pack application Week 3-6 Straight leg raises with weights Hip abduction in weighted side lying Knee flexion in the prone position Knee extension in weight-bearing sitting Sliding forward in the chair to increase the knee flexion angle Standing weighted hip abduction Standing knee flexion with weight Squat Walking Climbing stairs Action observation therapy will be practiced by watching videos of all exercises with a focus on close-up action.
Study: NCT05689333

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vista Vitrectomy Probe
Description: Vitrectomy will be performed through 27 GA Vista Ophthalmics vitrector