Study: NCT05519839

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIC Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of co-formulated mix of various doses and formulations of CIC Vaccine given on Day 0 and Day 70

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator
Description: Intramuscular (deltoid) injection of placebo given on Day 70.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 rS Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of in-clinic mix of various doses of SARS-CoV-2 rS vaccine given on Day 0 and Day 70 .

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 rS Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of in-clinic mix of various doses of SARS-CoV-2 rS vaccine given on Day 0 and Day 70 .

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 rS Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of in-clinic mix of various doses of SARS-CoV-2 rS vaccine given on Day 0 and Day 70 .

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 rS Vaccine with Matrix-M Adjuvant
Description: Intramuscular (deltoid) injections of in-clinic mix of various doses of SARS-CoV-2 rS vaccine given on Day 0 and Day 70 .