Study: NCT06372483

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VMX-C001
Description: VMX-C001 is human factor X engineered to be insensitive to factor Xa DOACs

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VMX-C001
Description: VMX-C001 is human factor X engineered to be insensitive to factor Xa DOACs

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VMX-C001
Description: VMX-C001 is human factor X engineered to be insensitive to factor Xa DOACs

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VMX-C001
Description: VMX-C001 is human factor X engineered to be insensitive to factor Xa DOACs

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VMX-C001
Description: VMX-C001 is human factor X engineered to be insensitive to factor Xa DOACs

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: VMX-C001 matched placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: VMX-C001 matched placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: VMX-C001 matched placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: VMX-C001 matched placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: VMX-C001 matched placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 20 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Apixaban 5 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Apixaban 5 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Apixaban 5 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Edoxaban 60 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Edoxaban 60 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Edoxaban 60 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Edoxaban 60 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Edoxaban 60 mg Oral Tablet
Description: Fxa DOAC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Edoxaban 60 mg Oral Tablet
Description: Fxa DOAC