TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06743919

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium sulfate 50% - 1g/h
Description: magnesium sulfate group 20 ml bupivacaine 0.25% plus 500 mg magnesium sulfate in 5ml normal saline on both sides.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dexmedetomidine 0.5 µg/kg IV
Description: dexmedetomidine group 20 ml bupivacaine 0.25% plus o .5 microg per kg dexmedetomidine in 5 ml normal saline on both sides.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine
Description: 20 ml bupivacaine 0.25% plus 5 ml normal saline on both sides.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine
Description: 20 ml bupivacaine 0.25% plus 5 ml normal saline on both sides.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Bupivacaine
Description: 20 ml bupivacaine 0.25% plus 5 ml normal saline on both sides.
Study: NCT06745219

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: herombopag
Description: receive harombopag for the prevention of thrombocytopenia in the next cycle of chemotherapy
Study: NCT06200116

Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study: NCT06743763

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: fNIRS-based neurofeedback
Description: fNIRS-based neurofeedback is provided during a simulated classroom scenario where the child participants are asked to learn to regulate their attention based on the feedback provided by the fNIRS on the oxygenated haemoglobin level in their prefrontal cortex.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: fNIRS-based neurofeedback
Description: fNIRS-based neurofeedback is provided during a simulated classroom scenario where the child participants are asked to learn to regulate their attention based on the feedback provided by the fNIRS on the oxygenated haemoglobin level in their prefrontal cortex.
Study: NCT04928287

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: HB-adMSCs
Description: HB-adMSCs will be administered intravenously to study participants who qualify.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: HB-adMSCs
Description: HB-adMSCs will be administered intravenously to study participants who qualify.
Study: NCT06743763

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtual Reality Simulated Classroom
Description: A simulated classroom scenario is integrated in VR setting and children are asked to complete academic tasks in the simulated classroom.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Simulated Classroom
Description: A simulated classroom scenario is integrated in VR setting and children are asked to complete academic tasks in the simulated classroom.
Study: NCT06745063

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin
Description: 12 week treatment with 10mg empagliflozin daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 12 week treatment with 10mg placebo daily
Study: NCT06743958

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise intervention
Description: Specific strength and balance training intervention during neoadjuvant chemotherapy, twice per week for 30 min, progression according to individual status
Study: NCT06744595

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood or salvia samples

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: Receive personalized EPIC message

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Genetic Counseling
Description: Receive pre-genetic test counseling

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Genetic Counseling
Description: Receive post-genetic test counseling

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genetic Testing for Cancer Risk
Description: Undergo SOC genetic testing

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study: NCT06744660

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Aptitude Medical Systems Metrix COVID Test
Description: The Metrix COVID Test is a real-time reverse transcription loop-mediated isothermal amplification reaction (RT-LAMP) test that has been designed to detect viral RNA from SARS-CoV-2 via electrochemical detection using the Metrix Reader. Detection of SARS-CoV-2 gene targets will produce a positive SARS-CoV-2 result. If no target is detected and the internal control amplifies, the result is negative. If no amplification is detected in any of the channels, an invalid result is displayed.
Study: NCT06744374

Intervention type: DRUG
Intervention: BGF
Description: Budesonide/glycopyrrolate/formoterol fumarate

Intervention type: DRUG
Intervention: MITT
Description: Multiple-inhaler triple therapy
Study: NCT06744855

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Non-invasive circulation gloves
Description: Non-invasive class I medical device, circulation gloves with semiconductors embedded in the fabric.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Fabric gloves
Description: These gloves will look and feel identical to the active circulation gloves, but will not have semiconductors embedded in the fabric.
Study: NCT06744426

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR1015
Description: One tablet administered alone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BR1015-2
Description: One tablet administered alone
Study: NCT04744662

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: sham injection
Description: sham injection is done by touching the eye surface with a syringe without a needle
Study: NCT06744426

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BR1015-3
Description: One tablet administered alone
Study: NCT06745687

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM336
Description: Patients received subcutaneous CM-336 80 mg once weekly in 28-d cycles after two step-up priming doses of 3 mg and 20 mg given on day 1 and day 4 of cycle 1 and cycle2. Then patients will be given 160mg every 2 weeks from cycle 3 to cycle 6. The dosing interval is adjusted according to the evaluation of efficacy every 6 cycles from cycle 7 to cycle 24.
Study: NCT06745089

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intense pulsed light
Description: Intense pulsed light exerts photothermal, photochemical effects, and photobiomodulation on meibomian glands.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: thermal pulsation therapy
Description: Thermal pulsation therapy utilizes local heating and massage on the eyelids.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ocular lubricant
Description: Ocular lubricants moisturize the ocular surface.
Study: NCT04928287

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered intravenously to study participants who qualify.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered intravenously to study participants who qualify.
Study: NCT06745791

Intervention type: DEVICE
Intervention: BoneMRI
Description: BoneMRI is a quantitative 3D MRI technique,capable of generating CT-like, quantitative radiodensity bone MRI images to visualize cortical and trabecular bone, allowing to assess bone structure and morphology, in addition to regular clinical MRI images.
Study: NCT06744504

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cytarabine
Description: Cytarabine combined with daunorubicin was used for induction therapy. According to the different doses of cytarabine, it was divided into standard dose group and intermediate dose group.In addition, high doses of cytarabine are also used for post-remission treatment.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cytarabine
Description: Cytarabine combined with daunorubicin was used for induction therapy. According to the different doses of cytarabine, it was divided into standard dose group and intermediate dose group.In addition, high doses of cytarabine are also used for post-remission treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: daunorubicin
Description: combined with cytarabine and used for induction therapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: daunorubicin
Description: combined with cytarabine and used for induction therapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: idarubicin
Description: combined with cytarabine and cyclophosphamide and used for post-remission treatment

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: idarubicin
Description: combined with cytarabine and cyclophosphamide and used for post-remission treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cyclophosphamide
Description: combined with cytarabine and idarubicin and used for post-remission treatment

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cyclophosphamide
Description: combined with cytarabine and idarubicin and used for post-remission treatment
Study: NCT04938349

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dual task perturbation training
Description: Participants will play six cognitive games targeting working memory, executive functioning, visuomotor reactions, and language fluency provided in standing. Following which they will receive 12 slips without performing cognitive task (Single task training) at the highest intensity and 12 slips during standing while performing a cognitive task (dual task). Also, they will then undergo 12 dual task walking trials (at self-selected speed) followed by 12 walking slips.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dual task perturbation training
Description: Participants will play six cognitive games targeting working memory, executive functioning, visuomotor reactions, and language fluency provided in standing. Following which they will receive 12 slips without performing cognitive task (Single task training) at the highest intensity and 12 slips during standing while performing a cognitive task (dual task). Also, they will then undergo 12 dual task walking trials (at self-selected speed) followed by 12 walking slips.
Study: NCT06183164

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindfulness: Awareness-Based Stress Reduction Program
Description: The mindfulness-based stress reduction program was applied to the patients in the experimental group once a week, for 150 minutes, for 8 weeks and 8 times in total. Then, an intermediate test is applied to the patients. After the interim test, patients are asked to repeat the mindfulness-based stress reduction program individually for 8 weeks (between weeks 8-16). In addition, after the conscious awareness-based stress reduction program is applied to the patients in the experimental group by the researcher, the 'Conscious Awareness-Based Stress Reduction Program' booklet prepared by the researcher is given to the patients as a guide. experimental group.
Study: NCT04938349

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dual task perturbation training
Description: Participants will play six cognitive games targeting working memory, executive functioning, visuomotor reactions, and language fluency provided in standing. Following which they will receive 12 slips without performing cognitive task (Single task training) at the highest intensity and 12 slips during standing while performing a cognitive task (dual task). Also, they will then undergo 12 dual task walking trials (at self-selected speed) followed by 12 walking slips.
Study: NCT04758403

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Navigation Bronchoscopy
Description: Navigation Bronchoscopy procedure will be performed per product instructions and the institution's standard practice.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Navigation Bronchoscopy
Description: Navigation Bronchoscopy procedure will be performed per product instructions and the institution's standard practice.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Cone beam computed tomography (CBCT)
Description: Per Protocol
Study: NCT04776005

Intervention type: OTHER
Intervention: Data collection
Description: Assessment of the efficacy and immunogenicity of the anti-Sars-COv2 vaccines in patients treated for malignant pathology.

Intervention type: OTHER
Intervention: Data collection
Description: Assessment of the efficacy and immunogenicity of the anti-Sars-COv2 vaccines in patients treated for malignant pathology.
Study: NCT05811208

Intervention type: DEVICE
Intervention: automated pupillometry
Description: Automated pupillometry every 6 hours

Intervention type: DIAGNOSTIC_TEST
Intervention: questionnaire
Description: CAM ICU questionnaire will be used for delirium screening the incidence of pain will be assessed using 3 valid scales. The Visual Analogue Scale (VAS), the Behavioral Pain Scale (BPS) and the Critical Care Observational Tool (CPOT) will be used.~questionnaires will be done the same time as pupillometry
Study: NCT04634877

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: IV infusion
Study: NCT05940649

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continuous norepinephrine administration
Description: In patients randomized to continuous norepinephrine administration, hypotension (= mean arterial pressure \< 65mmHg) will be treated with continuous norepinephrine infusion. The norepinephrine perfusion line will be connected to the saline infusion line using a three-way valve. Treating anesthesiologists will be free to reduce or increase the norepinephrine infusion rate anytime.
Study: NCT05394051

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive Affect Regulation sKills (PARK)
Description: The goal of the PARK program is to reduce feelings of anxiety, depression, and social isolation, as well as increase well-being and a sense of meaning and purpose through the practice of positive emotion skills via a self-guided online platform.~The total time involved from the beginning to the end of the intervention portion of the study is approximately 6 months (includes 6-week PARK course, baseline and follow-up assessments. Wait list controls will be assessed at similar time intervals and will be offered PARK at end of follow-up.
Study: NCT06290037

Intervention type: DEVICE
Group type: OTHER
Intervention: VR Driving Simulator
Description: Evaluation of usual road driving abilities and assessment of response capabilities in accident-prone situations through a VR driving simulator

Intervention type: OTHER
Group type: OTHER
Intervention: Computerized Neurocognitive Function Test
Description: Evaluation of cognitive levels including attention and memory (the Trail Making Test, Digit Span Test, Auditory (or Visual) Continuous Performance Test , and Card Sorting)

Intervention type: OTHER
Group type: OTHER
Intervention: Driver Test Station
Description: Conducting qualified tests of a person's basic physical driving ability including steering, acceleration and braking, using Driver Test Station(Autoadapt AB, Stenkullen, Sweden)

Intervention type: OTHER
Group type: OTHER
Intervention: Short Physical Performance Battery
Description: Evaluation of functional capability and provide a measure of the biological age of an older individual by measuring lower extremity physical performance status(standing balance, walking speed, and chair stand tests).

Intervention type: OTHER
Group type: OTHER
Intervention: On-road field driving Test
Description: Researchers and driver's license supervisors ride in the driver's license test vehicle to evaluate the subject's actual driving ability. the validity of the VR simulator by comparing the results of the VR simulator with the actual vehicle driving ability.
Study: NCT06518642

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sooma tDCS portable device - active stimulation
Description: Treatment followed common tDCS protocol upon considering safety and tolerability, comprising five consecutive sessions in five days of 30-minute 2 mA tDCS. We utilized the Soterix Medical tDCS device (Soterix Medical, New York, NY, USA, Model 1x1 tDCS-CT) in the research lab and the Sooma Oy device (Sooma Depression Therapy Comfort, Helsinki, Finland) for patient self-administration.Sooma provided two of their portable tDCS devices for a brief period, including one customized sham device.Due to the limited availability of the Sooma devices, participants were randomly allocated to either the Sooma or. Due to the limited availability of the Sooma devices, participants were randomly allocated to either the Sooma or the Soterix device based on availability during their initial session. A current of 2 mA was applied with the anode positioned left DLPFC, corresponding to area F3 in the international 10-20 system. The cathode (reference electrode) was applied at the right dPLFC, F4.
Study: NCT05930535

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parenting for Lifelong Health for Parents and Teens
Description: PLH will be delivered over 6 sessions as a group-based family program with both adolescents and caregivers attending, with joint and separate core sessions framed by joint introductions and endings. It will include activities such as: building positive parent-child relationships; developing problem-solving skills; stress-management and stress-reduction skills; improving effective limit-setting and discipline by parents; talking about feelings and regulating emotions.~The PLH program will also include a peer support component and incentive boosters. The Helping Adolescents Thrive comic chapters will be provided as homework activities. The comics, developed by UNICEF, cover adaptation to new situations, stress management, problem-solving, communication skills, risky choices and being there for each other.
Study: NCT04964752

Intervention type: DEVICE
Group type: OTHER
Intervention: continuous glucose-monitoring
Description: Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.
Study: NCT06518642

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sooma tDCS portable device - sham stimulation
Description: Sooma provided two of their portable tDCS devices for a brief period, including one customized sham device for effective blinding, distinguishable only by serial number and managed by an external data manager following the randomization sequence.To ensure blinding to the participant and their caregiver, at the beginning of the stimulation sessions, participants receiving both the active and sham stimulation would experience a ramp-up in current from 0 to 2 mA, and then the current would ramp down to 0 mA for participants receiving sham stimulation. Participants were told that they may experience sensations such as tingling, headache, or mild burning during the first 30-60 seconds of the stimulation session but that they may subside afterwards as they got used to it. In other words, participants would not be able to tell if diminishing of side effects were due to habituation (active tDCS) or ramping down of current (sham tDCS).
Study: NCT05706129

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-DPI-4452
Description: \[68Ga\]Ga-DPI-4452, administered as IV injection.
Study: NCT05706129

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-DPI-4452
Description: \[68Ga\]Ga-DPI-4452, administered as IV injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-DPI-4452
Description: \[68Ga\]Ga-DPI-4452, administered as IV injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [177Lu]Lu-DPI-4452
Description: \[177Lu\]Lu-DPI-4452, administered as IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [177Lu]Lu-DPI-4452
Description: \[177Lu\]Lu-DPI-4452, administered as IV infusion.
Study: NCT04964752

Intervention type: DEVICE
Group type: OTHER
Intervention: continuous glucose-monitoring
Description: Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

Intervention type: DEVICE
Group type: OTHER
Intervention: continuous glucose-monitoring
Description: Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

Intervention type: DEVICE
Group type: OTHER
Intervention: continuous glucose-monitoring
Description: Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.
Study: NCT06531512

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xianglei Tangzu Gao
Description: Active ingredients: Extracts of Plectranthus amboinicus and Centella Asiatica

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: Cream base of Xianglei Tangzu Gao
Study: NCT06287606

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTP0302-A
Description: Subjects randomized into group CTP0302-A will take a bowel preparation from the evening until the following morning.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTP0302-B
Description: Subjects randomized into group CTP0302-B will take a bowel preparation on the Colonoscopy day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Conventional OST
Description: Subjects randomized into group Conventional OST will take a bowel preparation from the evening until the following morning.
Study: NCT06458426

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: shock-absorbing prosthesis
Description: the intervention will test the difference between rigid and shock-absorbing pylons, while the same prosthetic foot is applied in each condition.
Study: NCT04885530

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin
Description: Each participant will receive a sufficient quantity of 7-mg tablets to be taken as directed based on their weight. The tablets are white, round, biconvex tablets with 123 over the scoring on one side. All packaging will be labeled to indicate that the product is for investigational use.