TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06050174

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azadirachta Indica
Description: Azadirachtaindica L. is a multipurpose medicinal tree of family Meliaceae.Is also named Nimba, holy tree, Vembu, Arishtha, Indian neem tree, Indian lilac, wonder tree. It occurs in tropical and semitropical regions of the world. Almost all parts of this incredible tree have been used as phytomedicines for more than 4,000 years.~Various pharmacological attributes such as antifungal, antiviral, antibacterial, anti-inflammatory, sterilant, antiscabic, antiallergenic and analgesic are attributed to various parts of the tree.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non Surgical Periodontal Therapy
Description: The patients will receive full mouth one stage debridement using ultrasonic scalers, manual scalers and curettes with oral hygiene instructions and education.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Non Surgical Periodontal Therapy
Description: The patients will receive full mouth one stage debridement using ultrasonic scalers, manual scalers and curettes with oral hygiene instructions and education.
Study: NCT05347186

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Systematic corrective exercises and non-biomechanical functional exercises
Description: 1. Restraint exercise or self-release: will involve the gastrocnemius muscle, soleus muscle, fibula, knee compressor muscles, adductors of the thighs, the short head of the biceps femoris, and iliotibial band for 30 seconds, using a foam roller.~2. Static stretching drills: involving the soleus and gastrocnemius muscles on an inclined plane, tensor fasciae latae muscle, short head of the biceps femoris, and ilio- psoas muscle;~3. Resistance exercises: will consist of strengthening the eccentric muscles of the feet including dorsiflexion and knee inversion, adduction, and extension, external rotation of the hip joint with TheraBand exercise band, and strengthening the intrinsic muscles of the foot.~4. Integrative exercises: including the star balance test on all planes and resistive exercises.

Intervention type: OTHER
Group type: OTHER
Intervention: Non biomechanical functional exercises
Description: Conventional treatment involved Non biomechanical Functional exercises (NBF), these exercises indicated for the control group consists of dorsal and plantar flexion of the metatarsophalangeal joints in unloading of the subject in a long sitting position on a chair or couch with the knee at 90◦ for a period of eight weeks. Feet will be in hanging position to allow plantar flexion smoothly. The exercises will carry out daily without any kind of resistance for a period of 30s. A total of five series will be completed for each foot. These exercises will be considered as non-therapeutic which might have affected the foot's posture.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non biomechanical functional exercises
Description: Conventional treatment involved Non biomechanical Functional exercises (NBF), these exercises indicated for the control group consists of dorsal and plantar flexion of the metatarsophalangeal joints in unloading of the subject in a long sitting position on a chair or couch with the knee at 90◦ for a period of eight weeks. Feet will be in hanging position to allow plantar flexion smoothly. The exercises will carry out daily without any kind of resistance for a period of 30s. A total of five series will be completed for each foot. These exercises will be considered as non-therapeutic which might have affected the foot's posture.
Study: NCT04716452

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ceramide NanoLiposome (Ceraxa)
Description: Ceramide NanoLiposome will be given by IV twice a week. The dose, which is based on body size, will be increased for the next group of patients if the first group of patients tolerates that dose and it will decrease for the next group if they do not tolerate the dose.
Study: NCT06243874

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: greater occipital nerve block
Description: greater occipital nerve block

Intervention type: PROCEDURE
Group type: OTHER
Intervention: transnasal sphenopalatine ganglion block
Description: transnasal sphenopalatine ganglion block
Study: NCT05313451

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Soluble fiber
Description: 15g/day during 2 months

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Maltodextrin 15g/day during 2 months
Study: NCT06090214

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Liquid biopsy
Description: For cases: 60 mL blood sample (40 ml for CellSave analysis and 20ml for collection) at visit1 then 20 ml for CellSave analysis at visit2 and visit3 For controls: 40 ml (20ml for CellSave analysis and 20ml for collection) at visit1

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Liquid biopsy
Description: For cases: 60 mL blood sample (40 ml for CellSave analysis and 20ml for collection) at visit1 then 20 ml for CellSave analysis at visit2 and visit3 For controls: 40 ml (20ml for CellSave analysis and 20ml for collection) at visit1

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Liquid biopsy
Description: For cases: 60 mL blood sample (40 ml for CellSave analysis and 20ml for collection) at visit1 then 20 ml for CellSave analysis at visit2 and visit3 For controls: 40 ml (20ml for CellSave analysis and 20ml for collection) at visit1
Study: NCT06003114

Intervention type: DRUG
Intervention: Palbociclib
Description: Participants taking oral palbociclib as prescribed in first-line treatment.
Study: NCT04749823

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blended treatment program
Description: A combined treatment program with specific active neck exercises and general aerobic training in counteractive amount will be executed during 12 weeks. Nine supervised sessions will be supplemented with 1 to 3 weekly unsupervised home exercise sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Specific strength exercise program
Description: This program includes an individual, patient-tailored exercise program with the aim of retraining the neck musculature. A detailed exercise programme will be constructed in which all exercises are listed with the amount of repetitions and series of each exercise. Strength exercises will be performed by means of dumbbells with different weights and elastic bands with different degrees of resistance. The amount of weight or resistance, and the amount of series and repetitions will be evaluated during the first session. This exercise programme will be re-evaluated repeatedly during the course of the program. Specific strength neck exercises will be performed for 30 minutes. Nine supervised sessions will be supplemented with 1 to 3 weekly unsupervised home exercise sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: General aerobic exercise program
Description: This control group will receive a general aerobic exercise program. Within a 12-week period, patients will be instructed to perform a general aerobic exercise session 3 times a week.
Study: NCT05793671

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PPCI in heavy thrombus burden STEMI patients
Description: minimally invasive procedures used to open clogged coronary arteries

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PPCI in heavy thrombus burden STEMI patients
Description: minimally invasive procedures used to open clogged coronary arteries
Study: NCT04816929

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bobath Method
Description: Neurodevelopmental Treatment

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Task-Oriented Approach
Description: Task-Oriented Treatment
Study: NCT04882592

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SCiP
Description: Noninvasive spinal cord neuromodulator

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SCiP
Description: Noninvasive spinal cord neuromodulator
Study: NCT05627063

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABSK121-NX
Description: In the escalation part, patients will receive a single dose of oral ABSK121-NX on Day -7 followed by a 7-day washout (Day -7 dosing day as 1st day of wash out) as a run-in period to access the safety and PK of ABSK121-NX. Then, patients will continuously receive ABSK121-NX once daily (QD) starting at C1D1 and continuing in subsequent cycles (28-day cycles). The starting dose is 3mg QD. In the expansion part, patients will each receive oral ABSK121-NX at the RDE in repeated 28-day cycles.
Study: NCT06246565

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10383
Description: HS-10383 administered as one 50 mg, 100 mg 200 mg tablet once daily, depending upon randomization.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10383
Description: HS-10383 administered as one 50 mg, 100 mg 200 mg tablet once daily, depending upon randomization.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10383
Description: HS-10383 administered as one 50 mg, 100 mg 200 mg tablet once daily, depending upon randomization.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: HS-10383 Placebo
Description: HS-10383 administered as one 50 mg, 100 mg 200 mg tablet once daily, depending upon randomization.
Study: NCT06466148

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: JessieHug
Description: Assessment of JessieHug device when placed on infants.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: JessieHug
Description: Assessment of JessieHug device when placed on infants.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: JessieHug
Description: Assessment of JessieHug device when placed on infants.
Study: NCT04673292

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fixed site standard of care testing
Description: This arm includes all three Johns Hopkins (JHMI) ambulatory outdoor testing sites across Baltimore City. Each site represents a traditional appointment-based scheduling system. Participants will be given a choice of 1 of 3 outdoor testing locations based on their preferences. Study staff will make an appointment for testing based on testing availability and participant schedule.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community-based, mobile van testing
Description: This arm offers the convenience of highly accessible testing and with the flexibility of no fixed appointment time. Each of the 12 geographic strata will have a single, centrally located testing site within the area, providing similar geographic access across households. The testing location will be published on the study website and social media so that participants can visit the location at a time convenient to them.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-collected, home-based testing
Description: Individuals will receive a home-based testing kit delivered by a courier service as soon as the randomization of the household is complete. The kit will include provisions for contacting the courier service for pick up. Appropriate biohazard precautions are included. Each of the testing components of this kit will include FDA Emergency Use Authorization approved collection methods. Easy to use instructions with options to view pre-recorded videos and/or virtual 'on demand' coaching sessions with members of the study team via a HIPAA-secure Zoom session will be available.
Study: NCT04577950

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lymphatic drainage of endometrial cancer
Description: Nanocoll® is injected a day before surgery in the cervix at four points. A lymphoscintigraphy is performed 2 or 3 hours afterward. At the beginning of the surgery, the operative field already in place and before the beginning of laparoscopic, 2ml (10mg) of ICG, distributed in four points around the tumor, is injected under the endometrium intra-myometrial under endoscopic control. As ICG spreads slower than blue dye, ICG is always injected first. Then, Bleu Patenté® is injected at two sites in the uterine isthmus, opposite of the uterine arteries. The risk of false negative results, because a tracer migrated too quickly, is reduced when the injection takes place when patients are already anesthetized.
Study: NCT06310681

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Encompass group programme
Description: * Groups will take place over ten modules~* They will take place in-person at a local community venue~* The groups will be two hours long, with a break for refreshments in the middle. They will take place every fortnight in term-time only over approximately 6 months.~* The groups predominantly follow a participatory learning approach and although the facilitators have manuals, the activities tend to include some imparting of information, key points for discussion, examples from other settings and activities for the group to practice.~* They are run by two facilitators - one parent with lived experience and one healthcare professional
Study: NCT05536310

Intervention type: DEVICE
Intervention: Transcatheter Aortic Valve Implantation (TAVI)
Description: TAVI with the JenaValve Trilogy Heart Valve System
Study: NCT04891068

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: 5-Azacitidine is a pyrimidine nucleoside analog in which nitrogen replaces carbon at position 5
Study: NCT05587855

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-group
Description: Participants with Hypertension will be assigned to eCulinary medicine
Study: NCT05120895

Intervention type: DRUG
Intervention: Mevalotin
Description: Oral tablets (starting dose 5 mg)
Study: NCT05099627

Intervention type: OTHER
Intervention: The questionnaire Cervical myelopathy treatment outcome questionnaire
Description: Information gathered through clinical examination and questionnaires performed retrospectively over the phone, pre-operation and at 3- and 6-months post-operation. The questionnaire Cervical myelopathy treatment outcome questionnaire attached records information relating to co-morbidities and symptomology. The examination will be a thorough neurological examination in addition to a focused cardiovascular examination. Biochemical blood markers from existing blood markers or from GP records, which have been or would have been performed regardless of this trial. Radiological findings will be taken from routine MRI and cervical spine X-rays performed as part of the CSM diagnostic work-up

Intervention type: OTHER
Intervention: The retrospective questionnaire CSM early diagnosis questionnaire
Description: To identify early clinical predictors of cervical myelopathy diagnosis based on individual patient-reported symptoms by using a questionnaire and patient characteristics as well as co-morbities, as well as clinical examination findings provided by community musculoskeletal teams.

Intervention type: OTHER
Intervention: JOACMEQ questionnaire and mJOA
Description: Used for prospective cohort via telephone at 3, 6 and 12-months post-operatively to assess treatment outcomes.
Study: NCT06477874

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dental implants placement
Description: implants placed in consolidated bone grafts

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dental implants placement
Description: implants placed in consolidated bone grafts
Study: NCT05599542

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Solution-oriented approach
Description: A preliminary assessment of the pregnant woman's thoughts on breastfeeding was made and the EARS (Eliciting, Amplifying, Reinforcing and Start Over) process was applied. Eliciting, Amplifying, Reinforcing and Start Over process guides the second and subsequent sessions in a sequential order. The Eliciting, Amplifying, Reinforcing and Start Over technique reminds the counselor of the basic concepts of solution-oriented approach and its explanation is as follows;

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Solution-oriented approach
Description: A preliminary assessment of the pregnant woman's thoughts on breastfeeding was made and the EARS (Eliciting, Amplifying, Reinforcing and Start Over) process was applied. Eliciting, Amplifying, Reinforcing and Start Over process guides the second and subsequent sessions in a sequential order. The Eliciting, Amplifying, Reinforcing and Start Over technique reminds the counselor of the basic concepts of solution-oriented approach and its explanation is as follows;

Intervention type: OTHER
Group type: OTHER
Intervention: Solution-oriented approach
Description: A preliminary assessment of the pregnant woman's thoughts on breastfeeding was made and the EARS (Eliciting, Amplifying, Reinforcing and Start Over) process was applied. Eliciting, Amplifying, Reinforcing and Start Over process guides the second and subsequent sessions in a sequential order. The Eliciting, Amplifying, Reinforcing and Start Over technique reminds the counselor of the basic concepts of solution-oriented approach and its explanation is as follows;

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hypno-breastfeeding
Description: A preliminary assessment was made about the pregnant woman's thoughts on breastfeeding. In the hypno-nursing philosophy, affirmation, relaxation, imagination and visualization techniques were used in order to positively affect the subconscious mind during the breastfeeding process.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hypno-breastfeeding
Description: A preliminary assessment was made about the pregnant woman's thoughts on breastfeeding. In the hypno-nursing philosophy, affirmation, relaxation, imagination and visualization techniques were used in order to positively affect the subconscious mind during the breastfeeding process.

Intervention type: OTHER
Group type: OTHER
Intervention: Hypno-breastfeeding
Description: A preliminary assessment was made about the pregnant woman's thoughts on breastfeeding. In the hypno-nursing philosophy, affirmation, relaxation, imagination and visualization techniques were used in order to positively affect the subconscious mind during the breastfeeding process.
Study: NCT06265675

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenol
Description: Chemical neurolysis

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Celestone
Description: Chemical neurolysis with corticosteroid

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocain
Description: Chemical neurolysis with local anesthetic
Study: NCT06461975

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Benoxinate Hydrochloride
Description: The first group had the first examination done using the tear substitute Polyfresh ® eye drops and the second using the Benoxinate HCL drops Benox ® given just before the ROP screening.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: artificial tear (Sodium Hyaluronate 2 mg/ml) eye drops.
Description: The second group had the first examination done using the Benoxinate HCL drops Benox ® eye drops and the second using the tear substitute Polyfresh ®given just before the ROP screening.
Study: NCT05514379

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive training
Description: Cognitive training focused on executive function, attention and working memory delivered either by the therapist in a group setting (experimental group) or by a specialized software for cognitive training (Rehacom) at home.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: cognitive training
Description: Cognitive training focused on executive function, attention and working memory delivered either by the therapist in a group setting (experimental group) or by a specialized software for cognitive training (Rehacom) at home.
Study: NCT06398548

Intervention type: OTHER
Group type: OTHER
Intervention: Control Group
Description: Participants continue with their lifestyle as usual, with no modification to lifestyle, or exercise habits.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate Intensity Continuous Training
Description: This group cycles at 70% of the resistance associated with their first lactate threshold.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heavy Intensity Continuous Training
Description: This group cycles at 10% of the difference between the resistance associated with their lactate threshold, and maximal achieved watts, added to the resistance associated with their lactate threshold.
Study: NCT05241730

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Training intervention
Description: The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training intervention
Description: The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training intervention
Description: The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High Glycaemic Index
Description: The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from high glycaemic index carbohydrates per day, the other E-% are fats and proteins.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LCHF
Description: The subjects eat ≥ 65 E-% fats and a maximum of 50 g carbohydrates per day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low Glycaemic Index
Description: The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from low glycaemic index carbohydrates per day, the other E-% are fats and proteins.
Study: NCT05644028

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Regulation Intervention for ADHD
Description: The intervention will be based on principles from dialectic behavioral therapy. The overall aim of the intervention is to improve emotion regulation skills. The intervention will consist of eight face-to-face group sessions and a digital companion app that the participants can use to practice skills between the sessions. The groups will include mindfulness-based exercises, homework review, introduction to new skills, and peer discussions.