TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06600958

Intervention type: OTHER
Intervention: SA brief descriptive name used to refer to the intervention(s) studied
Description: Details that can be made public about the intervention

Intervention type: OTHER
Intervention: SA brief descriptive name used to refer to the intervention(s) studied
Description: Details that can be made public about the intervention
Study: NCT06588699

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Digoxin
Description: Taken orally once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Digoxin
Description: Taken orally once daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched Placebo taken orally once daily
Study: NCT06597149

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Auricular Vagus Nerve Stimulation
Description: Healthy adult participants will be assigned to either the stimulation group or the sham group. The stimulation group will receive mild stimulation from the TeNS device and the sham group will receive no stimulation but will believe that they are receiving stimulus.
Study: NCT06601036

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane
Description: Patients will undergo fiberoptic intubation under sevoflurane sedation.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2% Xylocaine (2 ml )
Description: Patients will undergo fiberoptic intubation with bilateral Superior Laryngeal Nerve block and Recurrent laryngeal nerve block.
Study: NCT06596551

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pre-Post ARCH Intervention
Description: Stroke dyads, consisting of a survivor and primary family caregiver, will engage in a 4 weekly, 1.5 hour experiential dyadic sessions, totalling 6 hours of participation. In Week 1, dyads acknowledge the losses occurring after the stroke to normalize feelings of grief and sadness and find comfort within the familial space. In Week 2, dyads interpret their post-stroke losses within the framework of their existing knowledge for managing adversities (strengths, resources, and values) and identify changes that are most meaningful to them. In Week 3, dyads set specific, measurable, and achievable goals to actualize the meaningful changes identified in Week 2. Finally in Week 4, dyads bring together their individually derived strengths from the previous sessions to culminate into strengthened dyadic bonds. The exercise will also encourage participants to expand beyond the dyadic space to seek support from their communities, social networks and care services that are available to them.
Study: NCT06600451

Intervention type: OTHER
Intervention: observational study, no intervention is required
Description: Retrospective chart review, investigators provides data after reviewing patient\&#39;s existing medical record; no interaction with patients is required.~Patients were treated as per standard of care
Study: NCT06591143

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ART
Description: Caries excavation with hand instruments only and restoration with glass ionomer filling

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hall technique
Description: Stainless steel crown placement without tooth preparation
Study: NCT06600035

Intervention type: DEVICE
Intervention: Gastric ultrasound
Description: A curved array, low-frequency (2-5 MHz) transducer providing a scan depth up to 30 cm will be used. Patients will be scanned in the supine position followed by right lateral decubitus (RLD) position. The sonographic appearance of the gastric antrum will be classified as Grade 0,1 or 2, signifying empty antrum, fluid detected in RLD position only and antral fluid in both supine and RLD positions, respectively, based on the appearance in both the positions. Cross-sectional area (CSA) will be calculated by using two perpendicular diameters-anteroposterior (AP) and craniocaudal (CC) and the formula for area of an ellipse:CSA = (AP × CC × π)/4

Intervention type: DEVICE
Intervention: Gastric ultrasound
Description: A curved array, low-frequency (2-5 MHz) transducer providing a scan depth up to 30 cm will be used. Patients will be scanned in the supine position followed by right lateral decubitus (RLD) position. The sonographic appearance of the gastric antrum will be classified as Grade 0,1 or 2, signifying empty antrum, fluid detected in RLD position only and antral fluid in both supine and RLD positions, respectively, based on the appearance in both the positions. Cross-sectional area (CSA) will be calculated by using two perpendicular diameters-anteroposterior (AP) and craniocaudal (CC) and the formula for area of an ellipse:CSA = (AP × CC × π)/4
Study: NCT06246539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR mindfulness
Description: VR-based mindfulness
Study: NCT05902260

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutritional intervention
Description: Subjects should consume two 200 mL bottles of study product per day next to their cancer treatment (immunotherapy)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunotherapy
Description: Pembrolizumab monotherapy with or without combination chemotherapy according to standard of care
Study: NCT06586294

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: AK129 Drug：oxaliplatin Drug：capecitabine
Description: AK129 is administered intravenously according to the frequency every three weeks(Q3W) and different dosage of administration at different stages.Oxaliplatin is administered intravenously according to the frequency and dosage 130 mg/m2 on day 1 Q3W.Capecitabine is administered intravenously according to the frequency and dosage 1000 mg/m2 oral twice daily on day 1 to 14 Q3W.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: AK129 Drug：cadonilimab Drug：oxaliplatin Drug：capecitabine
Description: AK129 is administered intravenously according to the frequency Q3W and different dosage of administration at different stages. Cadonilimab is administered intravenously according to the frequency and dosage 10mg/kg Q3W.Oxaliplatin is administered intravenously according to the frequency and dosage 130 mg/m2 on day 1 Q3W.Capecitabine is administered intravenously according to the frequency and dosage 1000 mg/m2 oral twice daily on day 1 to 14 Q3W.
Study: NCT06592885

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Atraumatic Restorative Treatment in treatment of carious primary molars
Description: ART, which took place in Tanzania during the mid-1980s, is a conservative approach involving the removal of carious lesions using hand instruments, followed by the application of a glass ionomer restoration. This technique aims to be minimally invasive, promoting the preservation of tooth structure. The ART technique, employed in situations where ideal clinical conditions are challenging to achieve, has demonstrated effectiveness as a reliable method for managing cases where conventional treatment methods face resistance from children . However, concerns exist regarding the longevity of ART restorations and the impact of operator skill on outcomes.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hall Technique in treatment of carious primary molars
Description: The Hall technique, proposed by Norna Hall in the 1980s, involves the placement of preformed metal crowns on primary molars without any tooth preparation or local anesthesia.~Advocates of the Hall technique emphasize its simplicity, reduced need for traditional drilling, and high reported success rates in clinical studies.~However, concerns have been raised regarding long-term aesthetics and potential psychological impacts due to the visibility of metal crowns.
Study: NCT06602284

Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: Dermapen 4™
Description: Dermapen 4™ conjunction with MG-CLR
Study: NCT06599372

Intervention type: OTHER
Group type: OTHER
Intervention: The rTMS method
Description: The patient receives treatment under naturalistic conditions in routine practice.

Intervention type: OTHER
Group type: OTHER
Intervention: The cTBS method
Description: The patient receives the treatment under naturalistic conditions in routine practice.
Study: NCT06595368

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vimala massage
Description: The massage will be given three times per day, each lasting 15 minutes and planned one hour after the first feeding of each shift.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hydrotherapy
Description: Hydrotherapy will be applied two times per day before feeding, each lasting 5-10 min.
Study: NCT06604676

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: guided soft tissue grafting
Description: guided soft tissue grafting techniquea special digital guide was fabricated for one intervention non-guided soft tissue grafting technique receive the traditional technique without guide

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: non-guided soft tissue grafting technique
Description: the graft was taken with traditional technique without guide
Study: NCT06594939

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Polatuzumab Vedotin
Description: A combination of a monoclonal antibody and a chemotherapy drug.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mosunetuzumab
Description: A monoclonal antibody.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Chemotherapy drug, alkylating agent.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Chemotherapy drug, anthracycline antibiotic.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Steroid, anti-inflammatory

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pegfilgrastim
Description: Granulocyte stimulating factor, biologic response modifier.
Study: NCT06594900

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: resistance training intervention
Description: The RT intervention focuses on knee extensor muscles, following current guidelines. Children will attend two supervised 1-hour sessions per week, proven sufficient for adaptations. Trained coaches and a scientific assistant, supported by master students, will document the sessions. Sessions are spaced 48 hours apart, totaling 40 over 20 weeks, with eight sessions between PRE and MID.~Each session has three phases: warm-up, strength, and coordination. Warm-up involves whole-body games to increase heart rate and prepare for strength training. The strength phase, documented for effort and adjustments, includes squats, lunges, and step-ups, with intensity changes over time. Four sets of 8-12 repetitions per exercise are performed, aiming for strength increase and hypertrophy. Movements are done with great effort but not until voluntary failure.~The coordination phase focuses on age-appropriate strength and motor skills through a circuit of challenges.
Study: NCT05657015

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lepidium Sativum
Description: 2 ml of LS in situ gel at baseline

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Simvastatin
Description: 1.2% of SMV in situ gel at baseline
Study: NCT06590662

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Solriamfetol
Description: Patient with a diagnostic of idiopathic hypersomnia (ICSD-3 criteria) will be randomized to receive solriamfetol or placebo for 7 weeks of treatment period. For the experimental arm, the dose will be progressively increased beginning at 75 mg to 300 mg according to tolerance to treatment.~Solriamfetol will be taken once a day upon awakening Schema of dispensation~1. One tablet of solriamfetol 75 mg per day for 1 week (week 1)~2. 150 mg of solriamfetol per day for 2 weeks (weeks 2 and 3)~3. According clinical judgment, Dose either maintained stable at 150 mg or increased to 300 mg per day for 2 weeks (weeks 4 and 5).~4. Prescription at week 5: Dose maintained at 150 or 300 mg or reduced at 150 mg per day according to benefit and safety for 2 weeks.~Treatment duration: 7 weeks treatment period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patient with a diagnostic of idiopathic hypersomnia (ICSD-3 criteria) will be randomized to receive solriamfetol or placebo for 7 weeks of treatment period.~Placebo will be taken once a day upon awakening Schema of dispensation~1. One tablet of placebo per day for 1 week (week 1)~2. Two tablets of placebo per day for 2 weeks (weeks 2 and 3)~3. According clinical judgment, Either maintained stable with 2 tablets or increased to 4 tablets per day for 2 weeks (weeks 4 and 5).~4. Prescription at week 5: Dose maintained at 2 or 4 tablets or reduced at 2 tablets per day according to benefit and safety for 2 weeks.~Treatment duration: 7 weeks placebo period.
Study: NCT06597201

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: amino acid (15) peritoneal dialysis solution
Description: Subjects were treated with 1 bag of amino acid (15) peritoneal dialysis solution (2L) once every morning, and then with conventional glucose peritoneal dialysate (lactate).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: glucose peritoneal dialysis solution
Description: Subjects received conventional treatment with glucose peritoneal dialysis solution (lactate), which must include 1.5% glucose peritoneal dialysate (lactate) (2L) once.
Study: NCT06602440

Intervention type: PROCEDURE
Group type: OTHER
Intervention: The indwelling length of epidural catheter is 3 centimeters.
Description: When performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus（PIEB） mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups（3cm group 、5cm group and 7cm group）

Intervention type: PROCEDURE
Group type: OTHER
Intervention: The indwelling length of epidural catheter is 5 centimeters.
Description: When performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus（PIEB） mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups（3cm group 、5cm group and 7cm group）

Intervention type: PROCEDURE
Group type: OTHER
Intervention: The indwelling length of epidural catheter is 7 centimeters.
Description: When performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus（PIEB） mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups（3cm group 、5cm group and 7cm group）
Study: NCT06594731

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hip belt squat training
Description: Hip belt squat training performed twice per week for 6 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hip belt squat training
Description: Hip belt squat training performed twice per week for 6 weeks
Study: NCT06597474

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Food-Body-Mind
Description: The Food-Body-Mind intervention includes 3 main components: 1) a school-based mindfulness component delivered by daycare teachers to equip preschoolers with knowledge and skills in mindful eating and movement (e.g., yoga, deep breathing exercises) to reduce emotional eating and increase F/V intake and physical activity; 2) a home-based mindfulness component to increase caregivers' skills in practicing mindful eating, movement, and parenting behaviors at home to foster a more positive, mindful, and healthy home environment; and 3) a preschooler school learning and caregiver home practice connection component to improve caregiver-preschooler relationships.
Study: NCT06596252

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Budesonide
Description: Twice daily intake of the tablet 30 min after a meal

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Budesonide
Description: Twice daily intake of the tablet 30 min after a meal
Study: NCT06592352

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modafinil Generis 100 mg
Description: All participants enrolled in the study will receive the study intervention drug (Modafinil Generis 100 mg). Dose 200 mg once per day (2 tablets of 100 mg) in the morning for 3 months (84 days), Oral administration
Study: NCT06595264

Intervention type: PROCEDURE
Intervention: embolization therapy
Description: Embolization in the neuroradiological department is the Golden Standard for the treatment of vein of Galen malformations.
Study: NCT06595914

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical implementation strategies
Description: Clinical implementation strategies, selected based on ED clinician survey/interview findings from Aim 1 using the Implementing Promoting Action on Research Implementation in Health Services (i-PARIHS) implementation science framework
Study: NCT06598995

Intervention type: PROCEDURE
Intervention: Coronary artery bypass grafting or unroofing
Description: Patients had an MB with \&gt;75% compression degree would receive coronary artery bypass grafting, and those who underwent unroofing may had a depth of MB \&lt; 5mm (whether deal with these MB with a depth \&lt;5mm depends on the surgeon and the period time of patients received a surgery).
Study: NCT06588023

Intervention type: OTHER
Intervention: Observational study to evaluate professional practices
Description: It consists of collecting data prospectively on all pre-eclamptic patients undergoing a non-urgent cesarean section.~The objective is to observe the management of hemodynamics and calculate the prevalence of complications such as maternal hypotension and/or hypertension through the implementation of non-invasive monitoring (ClearSight).

Intervention type: OTHER
Intervention: Observational study to evaluate professional practices
Description: It consists of collecting data prospectively on all pre-eclamptic patients undergoing a non-urgent cesarean section.~The objective is to observe the management of hemodynamics and calculate the prevalence of complications such as maternal hypotension and/or hypertension through the implementation of non-invasive monitoring (ClearSight).
Study: NCT06588062

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Picture Exchange Communication System (PECS)
Description: Picture exchange communication System (PECS) is a widely useful tool for developing skills in ASD children. Visual supports rather work better for their intellectual level as these children usually respond less to verbal and written instructions. PECS is considered as an augmentative communication system commonly used with non-verbal ASD children. It is helpful for an individual with ASD to quickly acquire a functional means of communication. This is highly beneficial for the child to communicate with his parents and caregivers, as well as with their peers. Moreover, the pictorial approach of PECS is a source of facilitating element in attaining student's concentration. The reason for wide acceptance of this tool in clinical and social settings for children with ASD is its' ease of use, ability to teach two-way communication and inexpensiveness. PECS has demonstrated successful use in teaching various skills in ASD affected children lacking speech.
Study: NCT06586476

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nightly Timed Awakening
Description: Patients in this arm will be awakened 1-hr after going to bed by their caregiver(s) to use the restroom and then returned to sleep. This awakening will occur every night.
Study: NCT06599931

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: tACS Transcranial alternating stimulation
Description: session of 20 minutes

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: tACS Transcranial alternating stimulation
Description: session of 20 minutes

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: tACS Transcranial alternating stimulation
Description: session of 20 minutes
Study: NCT06596486

Intervention type: OTHER
Intervention: CoolStick
Description: Assessment of block using CoolStick.

Intervention type: OTHER
Intervention: Ethyl Chloride
Description: Assessment of block using ethyl chloride spray

Intervention type: OTHER
Intervention: Question
Description: Participant will be asked if they felt pain or not.
Study: NCT06586970

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Meals + RD services
Description: Registered dietitians (RD) will provide tailored dietitian counseling and nutrition education

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Meals + OT services
Description: Occupational therapists (OT) will provide tailored home safety recommendations and fall prevention education/strategies

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Meals + RD + OT services
Description: A combination of tailored registered dietitian and occupational therapy services will be provided
Study: NCT06596070

Intervention type: OTHER
Intervention: No intervention was carried out
Description: This study is an observational study and no intervention was performed on the patients.

Intervention type: OTHER
Intervention: No intervention was carried out
Description: This study is an observational study and no intervention was performed on the patients.
Study: NCT06597032

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resilience Challenge
Description: We previously have tested this online program in people facing health- and work-related stressors (e.g., dementia caregivers, healthcare workers), and in 2020 we enrolled adults in a test of the online program to support coping with the stress of the COVID pandemic. This intervention has been tailored for a widespread, public audience (e.g., we have added a few other safety measures including limits on public forum posting and have clarified wording on some of the intervention content to make it clearer and easier to understand).
Study: NCT06589193

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HOCl
Description: 10ml,twice a day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CHX
Description: 10ml,twice a day
Study: NCT06599086

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2 cc:(1 cc betamethasone dipropionate+1cc physiological saline)
Description: Each patient will receive 2 cc:(1 cc betamethasone dipropionate+1cc physiological saline) perineural injection into the median nerve under US guidance, for 1 session.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2 cc:(1 cc betamethasone dipropionate+1cc physiological saline)
Description: Each patient will receive 2 cc:(1 cc betamethasone dipropionate+1cc physiological saline) perineural injection into the median nerve under US guidance, for 1 session.
Study: NCT06090422

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Hydrochloride
Description: Four single-doses, given two times per week for two weeks Dose: 0,8 mg/kg body weight Route of administration: intravenous infusions over 40 minutes

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam Hydrochloride
Description: Four single-doses, given two times per week for two weeks Dose: 0,02 mg/kg body weight Route of administration: intravenous infusions over 40 minutes
Study: NCT04448392

Intervention type: DRUG
Group type: OTHER
Intervention: Valacyclovir
Description: Upon completion of standard of care acyclovir for treatment of neonatal HSV disease, valacyclovir oral suspension (per ASHP recipe), 20 mg/kg every 8 hours, to be given for 2 (up to 7) days