TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06226779

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baduanjin exercsie
Description: The Baduanjin exercise consists of 8 postures, with emphasis on different body parts. The exercise is commonly practiced as follows: (1) 2 hands holding up the heavens, (2) drawing the bow to shoot the eagle, (3) separating the heaven and earth, (4) wise owl gazing backwards, (5) swaying the head and shaking the tail, (6) 2 hands holding the feet to strengthen the waist, (7) clenching the fists and glaring fiercely, and (8) bouncing on the toes.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brisk walking
Description: The brisk walking will be gradually increased physical exertion from light to moderate of intensity. During the training period, the heart rate of participants will be monitored.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Health education
Description: Health education will include lecture classes. Video watching will watch videos which were not aim at improving physical exertion, such as sports games or sports related variety shows
Study: NCT06160063

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education intervention
Description: Board game was created in line with current literature. In each interview, it is expected that the child's negative behaviors will be transformed into positive behaviors.
Study: NCT05768152

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RLRL
Description: RLRL will be performed twice per day with an interval of at least 4 hours, each treatment last 3 minutes, in addition to single vision spectacles with power for correcting distance refraction.
Study: NCT04722471

Intervention type: DRUG
Intervention: Vaginally administered progesterone
Description: The artificial endometrial preparation for an embryo transfer with the use of 400 mg vaginal tablet (one tablet twice a day) or 200 mg (two tablets twice a day)

Intervention type: DRUG
Intervention: Vaginally administered progesterone
Description: The artificial endometrial preparation for an embryo transfer with the use of 400 mg vaginal tablet (one tablet twice a day) or 200 mg (two tablets twice a day)
Study: NCT06091709

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal Exercises and Education delivered through tele rehabilitation
Description: Participants will follow the MEET-R that will include stretching, strengthening and core stabilization exercises, and education material pertaining to the proper posture during work.

Intervention type: OTHER
Group type: OTHER
Intervention: Selafcare
Description: The control group is allowed to opt for self-care management of back pain in the form of medications, rest, conventional physiotherapy, and a home exercise plan. They are also allowed to change their self-care management during the study period; information about the use of the alternative management will be recorded. The information on self-care management will be gathered after 6 weeks at the end of the intervention
Study: NCT06251791

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physiotherapy+ IMT
Description: Conventional Physiotherapy to contain breathing and thoracal expansion exercises, bronchial hygiene techniques and gradual mobilization in 1 time a day. Conventional Physiotherapy to contain breathing and thoracal expansion exercises, bronchial hygiene techniques and gradual mobilization in 1 time a day. In this group addition to conventional physiotherapy inspiratory muscle training will be performed with the threshold-loaded inspiratory muscle training device, starting at 30% of the maximum inspiratory mouth pressure value, during 5 days, in 2 sessions, 4 sets per day, 6-8 breaths in each set and 2 minutes of rest between sets.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physiotherapy
Description: Conventional Physiotherapy to contain breathing and thoracal expansion exercises, bronchial hygiene techniques and gradual mobilization in 1 time a day. Conventional Physiotherapy to contain breathing and thoracal expansion exercises, bronchial hygiene techniques and gradual mobilization in 1 time a day.
Study: NCT05097534

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: iDSMES
Description: Intensive Diabetes Self-Management Education and Support combined with Addressing Social Determinants of Health

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard of Care
Description: Standard of Care for patients with type 2 diabetes
Study: NCT06508762

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-993
Description: Tablet and Suspension for Oral Administration.
Study: NCT06215404

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Liberal group
Description: Fluid challage to keep stroke volume variation \< 10%

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: restrictive group
Description: Fluid challage to keep stroke volume variation \< 18%
Study: NCT05184374

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gonadorelin
Description: GnRH pump pulse subcutaneous injection of gonadorelin in a month
Study: NCT06162156

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Back massage
Description: For the intervention group, massage will be given to the participant's back area by the researcher for 20 minutes, 12 hours after the cesarean birth. Preliminary data forms will be filled out by the participant before the massage. One hour after the massage, 'Visual Analog Scala' and 'Physiological Parameter Form' data will be filled in again. The final data forms will be filled out by the participant 24 hours after the cesarean birth, that is, 12 hours after the back massage.
Study: NCT02025712

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Exemestane
Description: Commercially available exemestane was supplied to sites as 25-mg tablets according to local regulations.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: Everolimus was administered by continuous oral dosing of two 5-mg tablets or one 10-mg tablets.
Study: NCT05652153

Intervention type: OTHER
Group type: OTHER
Intervention: Single-/paired-pulse transcranial magnetic stimulation
Description: Single-/paired-pulse transcranial magnetic stimulation (sp/ppTMS) is a technique for noninvasive assessment of brain physiology by delivering single or paired magnetic stimuli to the scalp with an electromagnetic coil. This results in transient induction of cortical electrical activity, which can be measured as evoked potentials by electromyography (EMG) and electroencephalography (EEG). Note that sp/ppTMS is used for neurophysiologic measurements; it is distinct from other TMS applications such as repetitive TMS, which can be used as interventions.
Study: NCT05457088

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1.5 protein
Description: dietary plan having dietary protein of 1.5 gr/kg/day

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 0.8 protein
Description: dietary plan having dietary protein of 0.8 gr/kg/day
Study: NCT05024903

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Serious illness medical planning plus the novel e-health platform (PWG 2.0)
Description: PWG 2.0 consists of the following components:~1. A diagnostic questionnaire, Preparedness for the Future Questionnaire and bench-marked report that helps users assess their strengths, weaknesses and opportunities for improvement.~2. A comprehensive e-workbook that helps users understand the science behind personal behavior change.~3. Links to webpages with additional e-workbooks and curated content aimed to help users progress on the 30 different attitudes, behaviors, and activities that portend for a better future (topics listed in Appendix A).~4. E-messages delivered via emails (via text an option for those that prefer) with tailored content designed to provide multiple nudges to guide the user to progress through our content.~5. Monthly newsletter with current topics and issues related to the 30 topics and behavior change in general.~6. A virtual consultation with Dr. Heyland, creator of PWG and principal investigator.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Participants are not planning for their future (PWG 2.0) or using the e-health platform
Study: NCT05501951

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tDCS stimulation
Description: The transcranial direct current stimulation (tDCS) method has emerged in the recent years as a non-invasive, safe, cheap, convenient and effective means to modulate brain functions and behaviours

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tDCS stimulation
Description: The transcranial direct current stimulation (tDCS) method has emerged in the recent years as a non-invasive, safe, cheap, convenient and effective means to modulate brain functions and behaviours

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: For the sham group, the electrode positioning will be randomly allocated to be identical to either the DLPFC or the OFC group, and active stimulation will be delivered for the first 30 seconds only
Study: NCT04772781

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S (+) - Ibuprofen
Description: S (+) - Ibuprofen + placebo of Ibuflex®

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuflex®
Description: Ibuflex® + placebo of S (+) - Ibuprofen
Study: NCT05126628

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Proxalutamide
Description: Proxalutamide 300mg q.d.(3 tablets of 100mg each) for 14 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 3 tablets q.d. for 14 days
Study: NCT05254873

Intervention type: OTHER
Intervention: Long term follow-up
Description: Long term follow-up for patient who completed the EYE-TAR(MA) study.
Study: NCT05504447

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rong-Yang Zhengyifang tea bag
Description: One tea bag is 4 grams, 3 bags per day, for a total of 7 days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo tea bag
Description: One tea bag is 4 grams, 3 bags per day, for a total of 7 days
Study: NCT05990868

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tylenol
Description: Rectal tylenol will be placed at the time of oocyte retrieval

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tylenol
Description: Rectal tylenol will be placed at the time of oocyte retrieval
Study: NCT05590026

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pectointercostal and ESP block
Description: Both Pectointercostal at between 4th and 5th costa and ESP block will apply at thoracal 6 level to the patient.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pectointercostal and ESP block
Description: Both Pectointercostal at between 4th and 5th costa and ESP block will apply at thoracal 6 level to the patient.
Study: NCT04760717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spironolactone Pill
Description: Participants randomized to the Spironolactone arm will be receiving Spironolactone in addition to their normal routine blood pressure treatment.
Study: NCT06155539

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05798286

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quantra
Description: The study plans to collect 2 additional 3 mL citrate tubes of venous blood in addition to the platelet and blood counts.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The study plans to collect 1 additional 3 mL citrate tubes of venous blood in addition to the platelet and blood counts at each time.
Study: NCT05356637

Intervention type: DEVICE
Group type: OTHER
Intervention: Werewolf Fastseal 6.0
Description: bi-polar hemostatic wand
Study: NCT06155539

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05453045

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albendazole
Description: tablet administration after a meal contaning approximate 15 g of fat
Study: NCT05974319

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry heat application
Description: Dry heat application: The region where the invasive intervention will be performed will be determined by the nurse in charge of the shift. The researcher will heat the thermoregulated electric pad and set it to 42°C. After making sure that there are no contraindications in the application of the electric pad device, a dry heat of 42°C will be applied to the determined area with the electric pad for 5 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry cold application
Description: Dry cold applicaiton: The region where the invasive intervention will be performed will be determined by the nurse in charge of the shift. After the researcher is sure that there are no contraindications in the application of the gel pad, dry cold will be applied to the determined area with the gel pad for 3 minutes.
Study: NCT06527534

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Filgotinib
Description: Patients will receive pills of Filgotinib 200 mg qd for 12 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adalimumab
Description: Patients will receive subcutaneous injections of Adalimumab 40 mg q2wk for 12 weeks
Study: NCT05199961

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Health Coaching
Description: The digital health coaching program consists of weekly calls and delivery of evidence-based content across health and wellness domains (e.g. nutrition, exercise, physical, emotional and financial health) up to 4 times weekly via text, email or mobile application. The program is 6-months in duration and designed for engagement following CAR T cell infusion.
Study: NCT05378061

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pituitary adenylate cyclase activating polypeptide-38
Description: Study participants will be allocated to receive continuous intravenous infusion of 10 pmol/kg/min PACAP-38.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study participants will be allocated to receive continuous intravenous infusion of 20 mL placebo (isotonic saline).
Study: NCT05342376

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine Hydrochloride
Description: The parturients will receive 10 micro-gram Dexmedetomidine diluted in 02 ml normal saline to be administered intravenously over 10 minutes after umbilical cord is clamped..

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Normal Saline
Description: The parturients will receive 02 ml normal saline as placebo, to be administered intravenously over 10 minutes after umbilical cord is clamped.
Study: NCT05208749

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Rotablation of shockwave
Description: Patients will be randomized to treatment with rotablation or shockwave

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Rotablation of shockwave
Description: Patients will be randomized to treatment with rotablation or shockwave
Study: NCT05343403

Intervention type: OTHER
Intervention: Family Integrated Care
Description: The intervention will consist of FICare, including parental participation in medical rounds (FCR). Parents and healthcare professionals will be educated and supported by the four pillars of FICare: parent education, education of healthcare professionals, psychosocial support and a supportive environment of the neonatal ward.
Study: NCT06289309

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neuromonitoring of the recurrent laryngeal nerves
Description: The NIM Vital system (Medtronic, Jacksonville, US) operates with surface electrodes integrated with an endotracheal NIM TriVantage tube 7.0-8.0 in diameter, which is inserted by an anesthetist between the vocal folds under direct vision during intubation. The standardized technique of IONM RLNs wll be used, including initial vagal response evaluation at the beginning and final vagal response evaluation at the end of surgery (IONM = L1+V1+R1+R2+V2+L2) according to the recommendations formulated by the International Intraoperative Neural Monitoring Study Group. The nerves will be stimulated using a monopolar electrode and the interrupted stimulation technique at 1mA, 100ms impulse duration and 4Hz frequency. In case of the bifurcated RLN nerves, the assessment includes post-stimulation response of each nerve branch. Adduction of the vocal folds is detected by the endotracheal tube electromyography and abduction by finger palpation of muscle contraction in the posterior cricoarytenoid.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neuromonitoring of the recurrent laryngeal nerves
Description: The NIM Vital system (Medtronic, Jacksonville, US) operates with surface electrodes integrated with an endotracheal NIM TriVantage tube 7.0-8.0 in diameter, which is inserted by an anesthetist between the vocal folds under direct vision during intubation. The standardized technique of IONM RLNs wll be used, including initial vagal response evaluation at the beginning and final vagal response evaluation at the end of surgery (IONM = L1+V1+R1+R2+V2+L2) according to the recommendations formulated by the International Intraoperative Neural Monitoring Study Group. The nerves will be stimulated using a monopolar electrode and the interrupted stimulation technique at 1mA, 100ms impulse duration and 4Hz frequency. In case of the bifurcated RLN nerves, the assessment includes post-stimulation response of each nerve branch. Adduction of the vocal folds is detected by the endotracheal tube electromyography and abduction by finger palpation of muscle contraction in the posterior cricoarytenoid.
Study: NCT05552872

Intervention type: DIAGNOSTIC_TEST
Intervention: mNGS, IDSeq UltraTM
Description: pathogen detection

Intervention type: DIAGNOSTIC_TEST
Intervention: mNGS, IDSeq UltraTM
Description: pathogen detection
Study: NCT04765046

Intervention type: DEVICE
Group type: OTHER
Intervention: Bispectral (BIS™) Complete Monitoring System
Description: The BIS™ Complete Monitoring System is a user-configurable patient monitoring system designed to monitor the hypnotic state of the brain based on the acquisition and processing of EEG signals. The BIS technology converts raw EEG data acquired from the frontal cortex into a single number to measure the level of consciousness, called the BIS index. A bilateral sensor is to be placed on the patient's forehead to collect the EEG signals and transmit them back to the system.
Study: NCT06246578

Intervention type: DEVICE
Group type: OTHER
Intervention: Continuos glucose monitoring and blood glucose measurement
Description: The individuals who use Dexcom G 7 sensors for continous glucose monitoring is in addition applied a Libre 2 sensor and asked to wear both sensors for 14 days. In case of a Dexcom glucose value \< 5 mmol/l, the participants is aked to measure a blood glucose as well uising fingerprick and Contour Next One
Study: NCT04686357

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: EMMA/ALICE
Description: Before randomization, an endometrial biopsy (EB) sample will be collected from all participants between day 15 and 25 of a natural cycle or after around 120 hours of progesterone (P) impregnation during a standard HRT cycle. The results of the EMMA/ALICE test will be provided to participants and their gynecologists. Depending on the test results, there are 3 different possibilities:~1. Normal result~2. Ultralow or Dysbiotic result~3. Abnormal result (pathogens) All probiotics and antibiotics that will be used in the study are already authorized by the local health authorities and will be prescribed under their technical data sheet/brochure conditions following the medical indications.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: EMMA/ALICE
Description: Before randomization, an endometrial biopsy (EB) sample will be collected from all participants between day 15 and 25 of a natural cycle or after around 120 hours of progesterone (P) impregnation during a standard HRT cycle. The results of the diagnosis will not be disclosed with the patients randomized into this arm nor with their gynecologists.
Study: NCT05404802

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental group intervention
Description: Training session~Facilitators will facilitate participants' interaction with PARO for 7 main activities, namely: (1) hugging PARO; (2) expressing emotions to PARO: (3) remembering PARO; (4) feeding PARO; (5) sleeping PARO; (6) bathing PARO; (7) decorating PARO.~Free-play session~In these sessions, every participant can interact with one PARO without instructions but are under the safety supervision of a PARO facilitator.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Control group intervention
Description: Facilitators will facilitate participants' interaction with PARO for 7 main activities, namely: (1) hugging PARO; (2) expressing emotions to PARO: (3) remembering PARO; (4) feeding PARO; (5) sleeping PARO; (6) bathing PARO; (7) decorating PARO.
Study: NCT05328817

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: In the absence of labor, broad-spectrum antibiotics (often called latency antibiotics) are recommended for women with PPROM less than 34 weeks to reduce chorioamnionitis, prolong latency, and decrease neonatal sepsis (12,13).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: In the absence of labor, broad-spectrum antibiotics (often called latency antibiotics) are recommended for women with PPROM less than 34 weeks to reduce chorioamnionitis, prolong latency, and decrease neonatal sepsis (12,13).
Study: NCT06225063

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates
Description: The application of pilates aims to correct real-time deviations observed in the body during movement, to maintain stability, to maintain stability, to gradually form proper sensorimotor ability and improve cervical dysfunction. Pilates is an important part but also a primary point in the stages of rehabilitation, since through it the execution of movement is encouraged earlier thus providing help for the later stages of rehabilitation. Pilates exercises concern movements at all levels of body movement and in various positions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive Functional Therapy
Description: Cognitive component: Educating patients about their perceptions of pain, explaining diagnosis and diagnostic findings, answering questions about their problem and symptoms, progressively challenge their customers in a non-judgmental way, education for multifactorial and biopsychosocial spectrum of pain, encouraging participants to movement and for active participation in daily activities, if receiving a self-management plan participation in activities with a degree of difficulty 2-3/10, tips for more effective sleep Specific functional training: Understanding pain modification through relaxation exercises, awareness and body control, modified body positions for better control of the cervical spine with parallel relaxation of the thoracic spine to participate in fearful or painful activities, engaging in movements of daily activities Lifestyle changes: Gradual increase in physical activity based on patient preferences, stress management and social interaction