Study: NCT05037162

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: POST- COVID-19 Functional Status Scale:
Description: performed on day 28. score: 0-3 ; a higher score indicates better recovery.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: POST- COVID-19 Functional Status Scale:
Description: performed on day 28. score: 0-3 ; a higher score indicates better recovery.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pregnancy test
Description: performed on days 1 and 28. women of childbearing potential must undergo a urine pregnancy test.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pregnancy test
Description: performed on days 1 and 28. women of childbearing potential must undergo a urine pregnancy test.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Pregnancy test
Description: performed on days 1 and 28. women of childbearing potential must undergo a urine pregnancy test.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Physical examination
Description: performed on days 1-14 and day 28. a full examination by a doctor.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Physical examination
Description: performed on days 1-14 and day 28. a full examination by a doctor.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Physical examination
Description: performed on days 1-14 and day 28. a full examination by a doctor.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PK parameters
Description: performed on day 1. will be performed only on 14 patients that will agree to participate in the PK analysis (only for Brazil,Spain).~The PK will be performed only for the first dose of drug, after patient received the first dose (5 puffs) the study staff need to follow the table below.~For each test, approximately 5 ml of blood will be drawn (equivalent to one teaspoon)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PK parameters
Description: performed on day 1. will be performed only on 14 patients that will agree to participate in the PK analysis (only for Brazil,Spain).~The PK will be performed only for the first dose of drug, after patient received the first dose (5 puffs) the study staff need to follow the table below.~For each test, approximately 5 ml of blood will be drawn (equivalent to one teaspoon)

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: PK parameters
Description: performed on day 1. will be performed only on 14 patients that will agree to participate in the PK analysis (only for Brazil,Spain).~The PK will be performed only for the first dose of drug, after patient received the first dose (5 puffs) the study staff need to follow the table below.~For each test, approximately 5 ml of blood will be drawn (equivalent to one teaspoon)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 test (PCR)
Description: performed on days 1,14 and 28.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 test (PCR)
Description: performed on days 1,14 and 28.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: SARS-CoV-2 test (PCR)
Description: performed on days 1,14 and 28.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ECG
Description: performed on days 1 and 28.