TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04813796

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1283
Description: Sterile liquid for injection
Study: NCT05544500

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sugar-free tablet
Study: NCT04813796

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1283
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1283
Description: Sterile liquid for injection
Study: NCT04976205

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Total Marrow (Lymph-node) Irradiation
Description: To the standard procedure for TMI/TMLI target definition, based on simulation WB-CT acquired 10/15 days before BMT, we acquire: WB- magnetic resonance imaging (MRI) the same day of the simulation WB-CT. A verification WB-CT will be performed 3/4 days before the delivery. Plans will be optimized with Volumetric Modulated Arc Therapy (VMAT) technique.
Study: NCT04813796

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1283
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection
Study: NCT06209736

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OMS906 study drug
Description: OMS906 study drug dose 5mg/kg IV administration at 4-week internals
Study: NCT05598411

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral Glucocorticoids
Description: methylprednisolone 24mg qd, 2-week duration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oral placebo
Description: oral placebo 24mg qd, 2-week duration
Study: NCT05697445

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobilization Techniques
Description: Combination of Cranial and Cervical Mobilization for Cervicogenic headache Patients treatment

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Treatment
Description: Cervicogenic headache exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Treatment
Description: Cervicogenic headache exercises
Study: NCT05011357

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenylephrine
Description: Phenylephrine will be administered as an infusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline Control
Description: Saline infusion
Study: NCT05469711

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PlayPhysio
Description: The gamification will be switched on at day 28 for the participants in arm 1. The trial will run for a further 84 days with the mid-point review half way through this section of the trial.
Study: NCT00455039

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GW572016
Description: Dose: 1500 mg daily
Study: NCT05762315

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio Storytelling
Description: The audio session is designed to deliver audio narrative developed following the Transformative Storytelling Technique and provide re-structurization of internal caregiver self-stories.
Study: NCT05031156

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Splinting of OT Bridge system
Description: splinting of implant abutment using titanium wire followed by pick up using the patient's denture

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Splinting of OT Bridge system
Description: splinting of implant abutment using titanium wire followed by pick up using the patient's denture
Study: NCT04765761

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PLMA with introducer
Description: The pro-seal laryngeal mask airway (PLMA) will be inserted along with introducer tool which will be kept in-situ throughout the duration of positive pressure ventilation

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PLMA without introducer
Description: The pro-seal laryngeal mask airway (PLMA) will be inserted along with introducer tool which will be removed after insertion and patient will be ventilated using PLMA without the introducer in-situ throughout the duration of positive pressure ventilation
Study: NCT05219448

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education and self-efficacy coaching
Description: Children and their caregiver(s) in the intervention communities will receive a culturally-adapted, 5-session program consisting of video-based health education and self-efficacy coaching delivered by an indigenous Community Health Worker. Families will be introduced to sugar-free water enhancers that are commercially available and come in the same flavors as regular Tang and Kool-Aid. The sessions will include conversations on related topics, interactive hands-on activities, and homework assignments. Additionally, four brief check-ins will keep families engaged. Local stores in the intervention communities only will carry the sugar-free water enhancers that are highlighted in the health education.
Study: NCT05007600

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online Interactive Courses
Description: In the experimental group, after consensus was reached in the expert meeting (consisting of a doctor specializing in occupational therapy, a doctor specializing in nursing, and a doctor specializing in public health), a 5-days-per-week (Monday to Friday) 8-week intensive online interactive course was designed. The course was made accessible to the participants through a social network app (Line) from 12:00 to 20:30.
Study: NCT04859062

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lidocaine gel 2%
Description: assessing its efficacy in decreasing muscle traction pain,In the operation room, we started inhalational induction of anesthesia with sevoflurane till the patient is deeply anesthetized. In the experimental group, we applied lidocaine gel 2% abundantly below both eyelids of the surgical eye for at least 3 minutes before the surgical incision, while nothing was applied to patients in the control group.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: control group
Description: In the operation room, we started inhalational induction of anesthesia with sevoflurane till the patient is deeply anesthetized. In control group, we didn't apply lidocaine gel 2% to the operative eye .
Study: NCT04886661

Intervention type: OTHER
Intervention: CHRONIC NECK PAIN
Description: Demographic information will be collected. Neck Disability Index will be filled. Physical examination will be performed.
Study: NCT05667376

Intervention type: OTHER
Group type: OTHER
Intervention: Local drug delivery
Description: Local application of curcumin gel into the periodontal pocket

Intervention type: DRUG
Group type: OTHER
Intervention: curcumin gel
Description: curcumin gel
Study: NCT04656600

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cerezyme® / Imiglucerase
Description: Pharmaceutical form: lyophilisate for solution for infusion Route of administration: intravenous
Study: NCT04999722

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Traditional mode of management
Description: Traditional model management of Diabetes Mellitus patients

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mobile APP management
Description: Management of diabetic patients with mobile phone APP
Study: NCT05771402

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD-1 antibody
Description: Once/two or three weeks, dose lower than the dose used in cancer patients, subcutaneous/intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NAs
Description: Once/day, 1 capsule/time, oral

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NAs
Description: Once/day, 1 capsule/time, oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peg-IFNα
Description: Once/week, 180μg/time, subcutaneous injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Peg-IFNα
Description: Once/week, 180μg/time, subcutaneous injection
Study: NCT06481202

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Complarate®
Description: The test drug Complarate® was administered as an intravenous infusion at a single dose of 8 mg/kg.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Actemra®
Description: The reference drug Actemra® was administered as an intravenous infusion at a single dose of 8 mg/kg.
Study: NCT05643573

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Asundexian (BAY2433334)
Description: Once a day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Apixaban
Description: 5 mg or 2.5 mg, twice a day, according to product label.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Asundexian matching placebo
Description: Placebo to asundexian, once a day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban matching placebo
Description: Placebo to apixaban, twice a day
Study: NCT05968157

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Breast MRI
Description: Supplemental MRI (in addition to standard of care MRI).

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Breast MRI
Description: Supplemental MRI (in addition to standard of care MRI).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MIRAI
Description: Artificial intelligence software
Study: NCT05965947

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Medical Nutrition Therapy
Description: One-on-one nutrition assessment, education, and counseling with a Registered Dietitian.
Study: NCT06172166

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transdisciplinary Care for Transition
Description: Young adults with T1D will participate in three visits during which they will see a diabetes nurse educator, psychologist, and transition navigator/social worker who will co-deliver care. TCT Visits 1 and 2 will be before the first adult diabetes healthcare visit, during trial months 1 and 2 respectively. These visits will focus on improving transition readiness, establishing care with an adult T1D specialist, and navigating psychosocial barriers to successful transition. TCT Visit 3 will occur after the first adult T1D healthcare visit, within one month of the first adult T1D care visit or during trial month 7 if the visit has not yet occurred. TCT Visit 3 will focus on overcoming barriers to satisfactory adult T1D healthcare.
Study: NCT06560723

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Quality of life test
Description: The results of the various quality-of-life scores used to compile the study statistics (ADL, iADL, MMS, GDS, MNA, EPICES, SPPB, SF-36) will be provided to the doctor, but without any specific comments or recommendations, and then presented to the patient. Number of emergency room visits and hospitalization days, drug untake evalautions and thepareutic compliance (GIRERD score) will be also collected.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Quality of life test
Description: The results of the various quality-of-life scores used to compile the study statistics (ADL, iADL, MMS, GDS, MNA, EPICES, SPPB, SF-36) will be provided to the doctor, but without any specific comments or recommendations, and then presented to the patient. Number of emergency room visits and hospitalization days, drug untake evalautions and thepareutic compliance (GIRERD score) will be also collected.
Study: NCT05568277

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education on preventive health behaviors based on Pender's Health Promotion Model
Description: Pregnant women included in the study will be given education on preventive health behaviors based on Pender's Health Promotion Model on the prevention of gestational diabetes over the web (ZOOM/Teams etc.) every two weeks. Pregnant women's questions will be answered. At the end of each training, data will be collected from pregnant women and follow-up charts will be filled. The education booklet prepared by the researcher will be given to the pregnant women after the first education and will be sent to their e-mail addresses.
Study: NCT06112249

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SAFE Employment Training
Description: The SAFE program includes lessons in the following areas: 1) Overview of What COVID-19 is and how it spreads 2) What is PPE and How to properly use 3) Social Distancing 4) Community Participation 5) Employment 6) Self Efficacy. We would also like to know if you learn more when the SAFE program is taught by a peer (person who also has an intellectual developmental disability).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SAFE Employment Training
Description: The SAFE program includes lessons in the following areas: 1) Overview of What COVID-19 is and how it spreads 2) What is PPE and How to properly use 3) Social Distancing 4) Community Participation 5) Employment 6) Self Efficacy. We would also like to know if you learn more when the SAFE program is taught by a peer (person who also has an intellectual developmental disability).
Study: NCT05520359

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobility Device
Description: Use of mobility device during session.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal Stimulation
Description: A stimulator will be used non-invasively stimulate the spine at the neck and/or lower back (cervical and/or lum
Study: NCT06006962

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aging Well through Interactions and Scientific Education - Action Plan
Description: 20-week program designed to provide education and individualized planning with a goal of improving brain health.
Study: NCT05608707

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity intervention
Description: The 12 week intervention will involve 2 weekly group exercise sessions incorporating strength and balance exercises, along with home-based exercise focused on increasing time spent walking.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity intervention
Description: The 12 week intervention will involve 2 weekly group exercise sessions incorporating strength and balance exercises, along with home-based exercise focused on increasing time spent walking.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Personalised nutrition intervention
Description: Two Plant-based Protein and Fibre (PPF) product products have been selected from six initially developed, with best amino acid blend, taste, and bioavailability. Participants will be provided with the PPFs to consume daily as part of a personalised diet over 12 weeks.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Personalised nutrition intervention
Description: Two Plant-based Protein and Fibre (PPF) product products have been selected from six initially developed, with best amino acid blend, taste, and bioavailability. Participants will be provided with the PPFs to consume daily as part of a personalised diet over 12 weeks.
Study: NCT06649929

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Couples-based treatment- Patient
Description: couples will attend 3-telehealth based sessions to provide eduction, increase self-efficacy and teach skils based in principles of brief behavioral therapy for insomnia

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Couples-based treatment- Partner
Description: couples will attend 3-telehealth based sessions to provide eduction, increase self-efficacy and teach skils based in principles of brief behavioral therapy for insomnia

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information control- Patient
Description: Information only plus treatment as usual
Study: NCT05876286

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurological examinations
Description: Neurological, neuropsychological, polysomnography examinations and multiple sleep latency test. The protocol is divided into three visits.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neurological examinations
Description: Neurological, neuropsychological, polysomnography examinations and multiple sleep latency test. The protocol is divided into three visits.
Study: NCT06341504

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prevention pop-up messages
Description: Messages are shown full screen on the EGM's play screen on a fixed presentation schedule. Clock of the gambling session starts the first time the participant puts money in the EGM. From this event, messages are shown at those timepoints: \[1\] +10 minutes; \[2\] +40 minutes; \[3\] +70 minutes; \[4\] +100 minutes. Messages block the screen for 15 seconds before automatically closing. Up to 4 different messages are presented during the gambling session. Order is determined by sortition without replacement.~Messages have a warning heading Caution!. Content is, from top to bottom: (a) time spent gambling from beginning; (b) warning that gambling could lead to serious monetary loss; (c) 1 of 4 self-appraisal phrases about current gambling behaviour; (d) advice to the participant that a break could help choose what is best for them; (e) countdown before the message closes itself; (f) Health department logo is shown in the lower right corner as a more neutral endorsement of the messages.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mandatory time limit
Description: Activated either when (a) the previous time limit is up; or (b) the player bank meter reaches $0. When the previous time limit is up, a pop-up takes up the upper third of the play screen and requires the player to set a new time limit using one of five choice buttons (four firsts buttons: 15, 30, 45 or 60 minutes; fifth button: cash out, which prints a receipt and ends the gambling session). As the EGM cannot track who is playing, there are no limits on consecutive gambling sessions. When the player's bank meter reaches $0, the the pop-up described above appears as soon as new money is inserted in the EGM, no matter if the previous time limit is up or not.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mandatory time limit
Description: Activated either when (a) the previous time limit is up; or (b) the player bank meter reaches $0. When the previous time limit is up, a pop-up takes up the upper third of the play screen and requires the player to set a new time limit using one of five choice buttons (four firsts buttons: 15, 30, 45 or 60 minutes; fifth button: cash out, which prints a receipt and ends the gambling session). As the EGM cannot track who is playing, there are no limits on consecutive gambling sessions. When the player's bank meter reaches $0, the the pop-up described above appears as soon as new money is inserted in the EGM, no matter if the previous time limit is up or not.
Study: NCT06649929

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information control- Partner
Description: Information only plus treatment as usual
Study: NCT06341504

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Responsible gambling information
Description: Located in a submenu accessed through a button on the main touch screen. This open a window which contains basic information on randomness and responsible gambling advice. The information is presented in small white font on a black background.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Responsible gambling information
Description: Located in a submenu accessed through a button on the main touch screen. This open a window which contains basic information on randomness and responsible gambling advice. The information is presented in small white font on a black background.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electronic gambling machine (model IGT GL20)
Description: EGM model currently in use in Quebec, Canada, the location where this study is conducted. The EGMs used in this study are fully functional and unaltered except for the presentation of prevention pop-up messages in the experimental arm of this study. These machines are equipped with basics responsible gambling features, the two main ones described in this section (i.e. Mandatory time limit; Responsible gambling information). Wins/losses sequence is fully randomized and not determined beforehand.
Study: NCT06653582

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Postural reeducation
Description: The program will include postural awareness, stretching, McKenzie's method, and manual therapy for 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic floor exercises
Description: The program will include pelvic floor exercises for 12 weeks. Three sets of 10 long contractions will be performed, each sustained for 6-8 seconds, three times a day. After each contraction, participants will be asked to rest for the same period. Two series of 10 fast contractions will be recommended, consisting of short, quick exercises of 1- to 2-second contractions, followed by long, sustained exercises lasting 5-10 seconds.
Study: NCT06341504

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electronic gambling machine (model IGT GL20)
Description: EGM model currently in use in Quebec, Canada, the location where this study is conducted. The EGMs used in this study are fully functional and unaltered except for the presentation of prevention pop-up messages in the experimental arm of this study. These machines are equipped with basics responsible gambling features, the two main ones described in this section (i.e. Mandatory time limit; Responsible gambling information). Wins/losses sequence is fully randomized and not determined beforehand.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Square terminal
Description: This terminal allows for buying non-alcoholic beverages (soft drinks or coffee) and chips during the experimentation. This is done to enhance the realism of the bar setting. It also allows for real cash withdrawal from bank account during gambling session. Quebec's code of conduct for EGMs commercialization prohibits retailers from having an ATM near their EGMs, and prohibits them from lending money to consumers or withdrawing cash for them to gamble. However, this rule is not always followed in practice. For this study, participants will be allowed to withdraw from their bank account, at the bar counter, if they ask for it. However, this will not be offered to them upfront.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Square terminal
Description: This terminal allows for buying non-alcoholic beverages (soft drinks or coffee) and chips during the experimentation. This is done to enhance the realism of the bar setting. It also allows for real cash withdrawal from bank account during gambling session. Quebec's code of conduct for EGMs commercialization prohibits retailers from having an ATM near their EGMs, and prohibits them from lending money to consumers or withdrawing cash for them to gamble. However, this rule is not always followed in practice. For this study, participants will be allowed to withdraw from their bank account, at the bar counter, if they ask for it. However, this will not be offered to them upfront.