TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05904990

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: traditional exercise therapy only
Description: 50-minute program included a 10-minute warm-up phase (treadmill walking at a comfortable speed), 30 minutes of stretching exercises for (glutei, paraspinal muscles, hamstring, pectoralis, scalenus, intercostal muscles, and trapezius), and a 10-minute cool-down involving self-stretching and respiratory exercises

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: traditional exercise therapy only
Description: 50-minute program included a 10-minute warm-up phase (treadmill walking at a comfortable speed), 30 minutes of stretching exercises for (glutei, paraspinal muscles, hamstring, pectoralis, scalenus, intercostal muscles, and trapezius), and a 10-minute cool-down involving self-stretching and respiratory exercises

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HILT alongside traditional exercise therapy
Description: YAG laser device (HIRO 3.0; ASA Laser, Arcugnano, Italy). This equipment delivers pulsed laser light at a wavelength of 1,064 nm, with a very high peak power of 3 kW and energy density ranging from 360 to 1,780 mJ/cm2. It operates with short pulse durations between 120 and 150 μs, at low frequencies of 10 to 40 Hz, and has a duty cycle of about 0.1%.
Study: NCT05704491

Intervention type: DIAGNOSTIC_TEST
Intervention: artificial intelligence (AI) algorithm of the MONA DR model
Description: A 45-degree fundus image is taken for each eye and patient using the Crystalvue NFC 600. The fundus photographs are then analyzed using the MONA DR model and classified for presence of diabetic retinopathy.

Intervention type: DIAGNOSTIC_TEST
Intervention: artificial intelligence (AI) algorithm of the MONA DR model
Description: A 45-degree fundus image is taken for each eye and patient using the Crystalvue NFC 600. The fundus photographs are then analyzed using the MONA DR model and classified for presence of diabetic retinopathy.

Intervention type: DIAGNOSTIC_TEST
Intervention: artificial intelligence (AI) algorithm of the MONA DR model
Description: A 45-degree fundus image is taken for each eye and patient using the Crystalvue NFC 600. The fundus photographs are then analyzed using the MONA DR model and classified for presence of diabetic retinopathy.

Intervention type: DIAGNOSTIC_TEST
Intervention: artificial intelligence (AI) algorithm of the MONA DR model
Description: A 45-degree fundus image is taken for each eye and patient using the Crystalvue NFC 600. The fundus photographs are then analyzed using the MONA DR model and classified for presence of diabetic retinopathy.
Study: NCT05070754

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP)
Description: The treatment device in this study generates cold atmospheric plasma. Cold atmospheric plasma has certain properties of plasma, such as ionized gas molecules. To create plasma, a pulse generator supplying 20 kilovolt pulse of 20-ns pulse width at 200 Hz (FPG10-01NM10, FID GmbH, Burbach, Germany) to a 5-mm diameter quartz-covered copper electrode of 10-cm length and 1 - 13mm quartz thickness. These nanosecond pulse parameters were chosen to provide sufficient treatment dose at the high level of plasma uniformity required to avoid any tissue damage. We will treat the lesions for approximately 1 to 2 minutes each, moving the electrode gently over the treatment area.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cryotherapy
Description: Cryotherapy refers to the application of liquid nitrogen using a cryospray device in order to freeze a lesion of interest. Treatment is repeated every few weeks until the lesion of interest has disappeared. It is considered SOC for the treatment of warts.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Canthardin Collodion
Description: Chemical compound that acts as a vesicant to form a blister around treatment area. The blister lifts the lesion of interest away from the skin, causing it to slough off in a few days. It is used as SOC for the treatment of Molluscum Contagiosum.
Study: NCT05073757

Intervention type: DEVICE
Intervention: Personalized guides and plates
Description: Patients will be included in the study and then followed clinically according to the routine care of orthognathic surgery with personalized guides and plates. The only specific act this study is the completion of an OQLQ quality of life questionnaire by patients preoperatively and between 8 to 12 months postoperatively.
Study: NCT05856747

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TBP-PI-HBr
Description: TBP-PI-HBr tablets.
Study: NCT06468046

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mama Empoderada [Mom Power]
Description: 'Mamá Empoderada' \[Mom Power\] is a theory-based, trauma-informed group intervention to promote mental health and positive parenting among mothers with young children (0-5 years). It has been adapted for migrant mothers, and will conduct a pilot randomized controlled trial (RCT) of the intervention with migrant mothers with young children (MMC). The intervention group (IG) will receive 10 group and 3 individual sessions addressing attachment theory, hands-on parenting skills, linkage to resources (e.g., food, shelter), social support, and self-care and resilience.
Study: NCT05692791

Intervention type: DIAGNOSTIC_TEST
Intervention: Two-point Discrimination Test
Description: Two-point discrimination (2PD) is the ability to discern that two nearby objects touching the skin are truly two distinct points, not one. It is often tested with two sharp points during a neurological examination and is assumed to reflect how finely innervated an area of skin is.

Intervention type: DIAGNOSTIC_TEST
Intervention: Two-point Discrimination Test
Description: Two-point discrimination (2PD) is the ability to discern that two nearby objects touching the skin are truly two distinct points, not one. It is often tested with two sharp points during a neurological examination and is assumed to reflect how finely innervated an area of skin is.

Intervention type: DIAGNOSTIC_TEST
Intervention: Semmes-Weinstein monofilament test
Description: Semmes-Weinstein monofilament test is used to assess light touch sensations.

Intervention type: DIAGNOSTIC_TEST
Intervention: Semmes-Weinstein monofilament test
Description: Semmes-Weinstein monofilament test is used to assess light touch sensations.
Study: NCT05459116

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Placement of nasogastric balloon
Description: A nasogastric balloon catheter will be inserted after inclusion. This will be a NutriVent (Sidam S.R.L., Mirandola, Italy) for patients \>40kg, and a SmartCath Esophageal pressure catheter (Vyaire/Carefusion) for patients \<40kg. This placement is similar to a standard nasogastric tube placement, which is a common procedure in an ICU. Potential minor side effects include a nosebleed, sore throat and erosion of the nose where the tube is anchored. All patients will receive this intervention. When the esophageal catheter becomes displaced or is accidentally removed during the study period, it will be replaced.
Study: NCT06241157

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pediatric Quiz Game
Description: Investigator will start interacting with children upon their arrival and during their presence in the waiting room before entering the operating room. This will help to obtain better cooperation (frankl scale) and anxiety reductions (FIS and VPT) at different stages of the dental examination (e.g., entering the clinic, sitting on the dental chair, opening mouth, examination with mirror, probe, use of low-high-speed handpieces, ITR restoration). Pediatric Quiz is actually an ice-breaking quiz game developed for children, with the promise of a surprise gift at the end. It can be defined as asking children basic questions on colors, animals, fruits and/or cities depending on the age of the child among which the child would choose him/herself and answer the question easily.
Study: NCT05939102

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: v-prep combined with RMGIC for bracket bonding
Description: prepare the tooth surface with the V-prep, then bond a bracket with the RMGIC

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Conventional bracket bonding technique
Description: prepare the tooth with acid-etch, then bond a bracket using resin composite
Study: NCT05123885

Intervention type: OTHER
Intervention: Study on Data
Description: Study on Data
Study: NCT05490095

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SVG101 (T)
Description: 5mg of SVG101

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SVG101 (T)
Description: 5mg of SVG101

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afinitor (R)
Description: 5mg of Afinitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afinitor (R)
Description: 5mg of Afinitor
Study: NCT05216146

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Strength and Conditioning
Description: A specially designed strength and conditioning program will be delivered for a period of 6 months from the experienced strength and conditioning coaches. The program will consist of the basic aerobic and anaerobic exercises that could be practiced without additional equipment and with own body weight.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strength and Conditioning
Description: A specially designed strength and conditioning program will be delivered for a period of 6 months from the experienced strength and conditioning coaches. The program will consist of the basic aerobic and anaerobic exercises that could be practiced without additional equipment and with own body weight.
Study: NCT05686252

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Held Position
Description: Change in angle of held position during kangaroo mother care to alternative angle

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Held Position
Description: Change in angle of held position during kangaroo mother care to alternative angle
Study: NCT05516407

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FEN164
Description: Oil based. Full-spectrum medicinal cannabis plant extract with less than 0.08% THC.
Study: NCT05814614

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: pelvic physical therapy
Description: Pelvic floor muscle exercises, biofeedback, bladder training

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: pelvic physical therapy
Description: Pelvic floor muscle exercises, biofeedback, bladder training

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: pelvic physical therapy
Description: Pelvic floor muscle exercises, biofeedback, bladder training
Study: NCT06054061

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: experimental wellbeing promotion group (Think and Cope Positively)
Description: Session 1: Welcome. 2: Identifying and amplifying positive emotions. 3: Experiencing positive emotions. 4: Identifying my negative trap thoughts. 5: Transforming my automatic thoughts into positive ones. Session 6: Experiencing my positive thoughts I. 7: Experiencing my positive thoughts II. 8: Learning to be kinder to myself. 9: Identifying a life project (Individual appointment).10: Identifying coping strategies I. 11: Identifying coping strategies II. 12: Identifying adaptive coping strategies linked to well-being. 13: Building my life purpose with my environment. 14: Helping me to build my life purpose? 15: Multi-family session, farewell and closing.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TAU
Description: The usual treatment in the intervention of people affected by severe mental disorder in the network of public and subsidized centers in Spain consists of improving psychosocial functioning. To this end, and depending on the characteristics of the user, work is done in groups and individually on social skills, psychoeducation about the disease, adherence to pharmacological treatment, improvement of daily living activities, promotion of independent leisure, support to families in the process of relapse prevention, and training for labor market insertion.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: TAU
Description: The usual treatment in the intervention of people affected by severe mental disorder in the network of public and subsidized centers in Spain consists of improving psychosocial functioning. To this end, and depending on the characteristics of the user, work is done in groups and individually on social skills, psychoeducation about the disease, adherence to pharmacological treatment, improvement of daily living activities, promotion of independent leisure, support to families in the process of relapse prevention, and training for labor market insertion.
Study: NCT04983238

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BYON5667 & SYD985
Description: Ocular administration: BYON5667, Intravenous administration: SYD985

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo & SYD985
Description: Ocular administration: Placebo, Intravenous administration: SYD985
Study: NCT04876664

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: measuring blood pressure with noninvasive blood pressure device
Description: To measure blood pressure in different circumstances with noninvasive blood pressure device
Study: NCT06096233

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bouts of Exercise
Description: The participants will run on the treadmill for 10 minutes (short) or 30 minutes (prolonged).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bouts of Exercise
Description: The participants will run on the treadmill for 10 minutes (short) or 30 minutes (prolonged).
Study: NCT04740879

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Be Mindful
Description: The online 4-week Be Mindful intervention was designed to follow the same outline as typical in-person 8-week MBCT courses. Week 1 and Week 2 introduce the topic of mindfulness and encourage its daily use, whereas Week 3 and Week 4 teach the individual to decenter from thoughts and utilize mindfulness when coping with stressors. Each week focuses on a separate mindfulness topic, which is initially presented to the individual in a short (under 5 minute) video containing didactic information and an overview of the experiential activities that will be introduced in subsequent videos. The intervention is provided entirely through audio, video, and text provided on the Be Mindful website (BeMindfulOnline.com).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Be Mindful
Description: The online 4-week Be Mindful intervention was designed to follow the same outline as typical in-person 8-week MBCT courses. Week 1 and Week 2 introduce the topic of mindfulness and encourage its daily use, whereas Week 3 and Week 4 teach the individual to decenter from thoughts and utilize mindfulness when coping with stressors. Each week focuses on a separate mindfulness topic, which is initially presented to the individual in a short (under 5 minute) video containing didactic information and an overview of the experiential activities that will be introduced in subsequent videos. The intervention is provided entirely through audio, video, and text provided on the Be Mindful website (BeMindfulOnline.com).
Study: NCT05205720

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Celiac plexus block
Description: The surgeon is instructed to perform a single celiac plexus block under direct vision. 10ml 0.5% ropivacaine is injected into the nerve in both sides.
Study: NCT05005013

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation (tDCS)
Description: tDCS is noninvasive brain stimulation device that modulates brain activity by delivering a low-intensity electrical current (2.0 mA) through sponge electrodes placed on the scalp.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham - Transcranial Direct Current Stimulation (tDCS)
Description: The tDCS device is programmed to mimic active tDCS.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: Participants will follow an audio track for guided mindfulness during the stimulation.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mindfulness
Description: Participants will follow an audio track for guided mindfulness during the stimulation.
Study: NCT05951088

Intervention type: PROCEDURE
Intervention: Cardio2U follow-up
Description: During the follow-up period, participants will have access to the application and will be able to explore the different modules. At fixed time points, the application will allow them to fill in questionnaires about the application's usability and patient satisfaction. App user data will track how long and how often patients visit the application and which aspects are mostly used. In addition, at different time points during the study, patients will be asked to complete clinical questionnaires regarding e.g. patients' knowledge and self-care abilities. The results of these questionnaires can be used in a more clinical way as they will be accessible to doctors and nurses in the healthcare provider dashboard and can support targeted patient follow-up and guidance

Intervention type: PROCEDURE
Intervention: Cardio2U follow-up
Description: During the follow-up period, participants will have access to the application and will be able to explore the different modules. At fixed time points, the application will allow them to fill in questionnaires about the application's usability and patient satisfaction. App user data will track how long and how often patients visit the application and which aspects are mostly used. In addition, at different time points during the study, patients will be asked to complete clinical questionnaires regarding e.g. patients' knowledge and self-care abilities. The results of these questionnaires can be used in a more clinical way as they will be accessible to doctors and nurses in the healthcare provider dashboard and can support targeted patient follow-up and guidance
Study: NCT06315660

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Miljeu Therapy
Description: TAU is an integrated voluntary inpatient treatment based on the principles of CBT, lasting between 12-20 weeks. This treatment includes exercise, close medical monitoring, group-based CBT for SUD, planning with social services, and is called Cognitive Milieu Therapy.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Miljeu Therapy
Description: TAU is an integrated voluntary inpatient treatment based on the principles of CBT, lasting between 12-20 weeks. This treatment includes exercise, close medical monitoring, group-based CBT for SUD, planning with social services, and is called Cognitive Milieu Therapy.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality based CBT for Anxiety
Description: The experimental intervention is a manualized add-on to TAU and comprises eight sessions of 60 minutes over a period of four weeks. Of these eight sessions, six will include 30 minutes of VR-based behavioral experiments targeting agoraphobic and social fear.
Study: NCT06170762

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pulp capping
Description: Pulp capping material for immature permanent teeth in case of carious or traumatic pulp expures

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulp capping
Description: Pulp capping material for immature permanent teeth in case of carious or traumatic pulp expures

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodiumhexametaphosphate
Description: Sodiumhexametaphosphate

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MTA
Description: MTA
Study: NCT05205720

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine
Description: Mixed solution for nerve block, made of 0.75% ropivacaine (Naropin, Astrazeneca AB) diluted in different proportions.
Study: NCT06514729

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adopting different ventilation modes during the operation
Description: The ventilation side adopts different ventilation modes combined with continuous positive pressure ventilation on the surgical side.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adopting different ventilation modes during the operation
Description: The ventilation side adopts different ventilation modes combined with continuous positive pressure ventilation on the surgical side.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adopting different ventilation modes during the operation
Description: The ventilation side adopts different ventilation modes combined with continuous positive pressure ventilation on the surgical side.
Study: NCT04756674

Intervention type: OTHER
Intervention: No intervetion will be used
Description: No intervention will be used

Intervention type: OTHER
Intervention: No intervetion will be used
Description: No intervention will be used

Intervention type: OTHER
Intervention: No intervetion will be used
Description: No intervention will be used
Study: NCT06106022

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Administered orally
Study: NCT05247424

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Unfractionated heparin
Description: Unfractionated heparin at dose of 100 IU /kg body weight
Study: NCT05306457

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNS10-NPC-GDNF
Description: Unilateral injections of CNS10-NPC-GDNF into the motor cortex

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNS10-NPC-GDNF
Description: Unilateral injections of CNS10-NPC-GDNF into the motor cortex
Study: NCT05819632

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: curcumin gel 2%
Description: curcumin gel 2%

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: curcumin gel 2%
Description: curcumin gel 2%
Study: NCT05828446

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MRI
Description: To compare the diagnostic performance of US+/- Constrast-enhanced US and AMRI for HCC detection in an at-risk population
Study: NCT06295159

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Nivolumab is a fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1 (PD-1, PCD-1) with immune checkpoint inhibitory and antineoplastic activities. Upon administration, nivolumab binds to and blocks the activation of PD-1, an immunoglobulin superfamily (IgSF) transmembrane protein, by its ligands programmed cell death ligand 1 (PD-L1), which is overexpressed on certain cancer cells, and programmed cell death ligand 2 (PD-L2), which is primarily expressed on antigen-presenting cells (APCs). This results in the activation of T cells and cell-mediated immune responses against tumor cells. Activated PD-1 negatively regulates T-cell activation and plays a key role in tumor evasion from host immunity.
Study: NCT05306457

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNS10-NPC-GDNF
Description: Unilateral injections of CNS10-NPC-GDNF into the motor cortex