TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05110430

Intervention type: OTHER
Intervention: Deep learning based detection of metastatic bone disease on bone scintigraphy scans.
Description: The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.

Intervention type: OTHER
Intervention: Deep learning based detection of metastatic bone disease on bone scintigraphy scans.
Description: The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.

Intervention type: OTHER
Intervention: Deep learning based detection of metastatic bone disease on bone scintigraphy scans.
Description: The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.
Study: NCT05817084

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: medial opening wedge high tibial osteotomy
Description: medial opening wedge valgus high tibial osteotomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: anterior cruciate ligament reconstruction
Description: anterior cruciate ligament reconstruction

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: anterior cruciate ligament reconstruction
Description: anterior cruciate ligament reconstruction
Study: NCT04911673

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: music
Description: Participants listened a song with headphones that lasts 29 minutes and 32 seconds for four days (three days before menstruation and the first day of menstruation).

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Chocolate group
Description: Participants ate 40 mg of dark chocolate with 60% cocoa per a day for four days (three days before menstruation and the first day of menstruation) that was given by researchers to them.
Study: NCT06102837

Intervention type: BIOLOGICAL
Intervention: tumor vaccine
Description: tumor vaccine produced by our team

Intervention type: RADIATION
Intervention: Radiotherapy
Description: conventional treatment in clincial

Intervention type: RADIATION
Intervention: Radiotherapy
Description: conventional treatment in clincial

Intervention type: DRUG
Intervention: Chemotherapy
Description: conventional treatment in clinical

Intervention type: DRUG
Intervention: Chemotherapy
Description: conventional treatment in clinical

Intervention type: PROCEDURE
Intervention: Surgery
Description: conventional treatment in clinical

Intervention type: PROCEDURE
Intervention: Surgery
Description: conventional treatment in clinical
Study: NCT05996354

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Concave Supra-arch Branched stent-graft system
Description: To evaluate the efficacy and safety of the Concave Supra-arch Branched stent-graft system for endovascular treatment of aortic arch diseases.
Study: NCT05843942

Intervention type: OTHER
Intervention: Questionnaire
Description: A food frequency questionnaire that was designed to assess folate, iron, and vitamin B12 intake will be administered. Furthermore a 24-hour recall food record will be administered and a complete blood count will be collected. Food frequency questionnaire data will be compared to recall food records and blood count data.
Study: NCT06102837

Intervention type: PROCEDURE
Intervention: Surgery
Description: conventional treatment in clinical
Study: NCT06086223

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ankle arthroscopy with ORIF
Description: we will go for fixation of the fracture with association of scope intervention pre and post fixation

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: fracture ankle fixation without ankle arthroscopy
Description: we will go for fixation of the fracture alone with no scope intervention
Study: NCT06530316

Intervention type: DRUG
Intervention: RET Inhibitor
Description: RET inhibitors for neoadjuvant treatment

Intervention type: DRUG
Intervention: RET Inhibitor
Description: RET inhibitors for neoadjuvant treatment

Intervention type: PROCEDURE
Intervention: Surgery
Description: Operable patients receive surgery after neoadjuvant therapy

Intervention type: PROCEDURE
Intervention: Surgery
Description: Operable patients receive surgery after neoadjuvant therapy
Study: NCT04408963

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VRC-HIVMAB0102-00-AB
Description: The VRC-HIVMAB0102-00-AB (CAP256V2LS) broadly neutralizing monoclonal antibody (bNAb) targets the V1V2 region of the HIV-1 envelope, is human in origin, and contains two amino acid modifications within the C-terminus of the heavy chain constant region designed to improve antibody half-life in vivo.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VRC-HIVMAB0102-00-AB
Description: The VRC-HIVMAB0102-00-AB (CAP256V2LS) broadly neutralizing monoclonal antibody (bNAb) targets the V1V2 region of the HIV-1 envelope, is human in origin, and contains two amino acid modifications within the C-terminus of the heavy chain constant region designed to improve antibody half-life in vivo.
Study: NCT06141135

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preimplantation genetic testing for aneuploidy (PGTA)
Description: 24 chromosome screening for aneuploidy in the preimplantation embryo(blastocyst stage)
Study: NCT05996887

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: standard care protcol
Description: All patients will receive antiemetics as haloperidol 2 mg and dexamethasone 8 mg and ondansetron 8 mg in addition to standard care protocol.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: enhanced recovery protocol
Description: All patients will receive antiemetics as haloperidol 2 mg and dexamethasone 8 mg and ondansetron 8 mg in addition to following the recommendation of ERAS society guidelines.
Study: NCT05362409

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5 Aminolevulinic Acid
Description: 5-aminolevulinic acid \[5-ALA\] administered orally 20 mg/kg every 4 weeks

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CV01-delivered ultrasound
Description: CV01-delivered ultrasound every 4 weeks
Study: NCT05605457

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PRG barrier coat + nanohybrid composite
Description: It is a light cured surface-partially reacted glass (S-PRG) filler particles with a multifunctional glass core embedded in a resin matrix.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: resin modified glass ionomer
Description: RMGIC are glass-ionomer cements with small quantity of monomers and initiators so the acid-base reaction is supplemented by a second polymerization reaction
Study: NCT05736952

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral Topotecan Combined With Anlotinib
Description: Topotecan hydrochloride capsules: 2 mg, once daily, oral with dinner for 5 days, discontinued for 16 days, that is, 21 days (3 weeks) as a course of treatment, a total of 6 courses of administration.；Anlotinib hydrochloride capsules: 10mg once a day, oral before breakfast, continuous administration for 14 days, discontinuation for 7 days, that is, 21 days (3 weeks) as a course of treatment.
Study: NCT05645224

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR-PAT
Description: Virtual Reality Pain Alleviation Therapy (VR-PAT) played on a Pico Neo 3 Pro Eye device
Study: NCT06170333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 8% sulphur and A. vera soap
Description: Patients in experimental arms will receive the combination of 8% sulphur and A. vera soap for four weeks along with 2% ketoconazole shampoo for a week.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 8% sulphur and A. vera soap
Description: Patients in experimental arms will receive the combination of 8% sulphur and A. vera soap for four weeks along with 2% ketoconazole shampoo for a week.
Study: NCT05239091

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dextrose solution
Description: A total of 3 doses of dextrose prolotherapy will be administered with an interval of 2 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocain
Description: A total of 3 doses of lidocaine will be administered with an interval of 2 weeks.
Study: NCT05181761

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gel Polish
Description: One hand of a subject with receive nail polish to compare bacterial growth between hands with gel nail polish to those without.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gel Polish
Description: One hand of a subject with receive nail polish to compare bacterial growth between hands with gel nail polish to those without.
Study: NCT04717999

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NKG2D CAR-T
Description: The NKG2D CAR-T will be administrated via intracerebroventricular injection through an Ommaya catheter. Standard treatments such as temozolomide will be stopped during the infusion of NKG2D CAR-T.
Study: NCT06165510

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Epicardial AF ablation using AtriCure EPi-Sense-AF Guided Coagulation System with Left Atrial Appendage Exclusion using the AtriCure LARIAT Suture Delivery Device.
Description: 2 stage procedure - minimally-invasive epicardial ablation with left atrial appendage exclusion using LARIAT procedure via a subxiphoid incision. This is then combined with endocardial radiofrequency catheter ablation in a separate staged procedure.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard Endocardial Catheter Ablation
Description: Standard percutaneous endocardial catheter ablation of atrial fibrillation
Study: NCT05409443

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA)
Description: * Electrodes are positioned along the lateral sacral crest lateral to the inflection points of the S1, S2 and S3 lateral foraminal walls along first to third transverse sacral tubercles maintaining a craniocaudal line with an interelectrode distance of no more than 15mm.~* The appropriate locations are confirmed in both AP and lateral views and the tines are deployed. Following injection of lidocaine, lesions are performed at 85 degrees Celsius for 180 seconds at each site for bipolar sites and 80 degrees Celsius for 90 seconds for the monopolar site. Following ablation, the tines are retracted for all electrodes prior to removal.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA)
Description: * To target the L4 medial branch and L5 dorsal ramus, an electrode will be placed in parallel between the junction of the L5 transverse process and superior articular process and the sacral ala and S1 superior articular process.~* A periforaminal electrode position will be used to target the lateral branches from S1 to S3. An 22-G cannula with a 5-mm exposed tip will be directed to a location approximately 3-5mm lateral to the PSFA of S1, S2, and S3. The analog clock positions for the probes at S1 and S2 levels will be 1:00, 3:00, and 5:30 on the right, and 6:30, 9:00, and 11:00 on the left. For the S3 level the positions at 1:30 and 4:30 on the right, and 7:30 and 10:30 on the left will be used (6,18).~* The appropriate locations are confirmed in both AP and lateral views. Following injection of lidocaine, monopolar RFA is performed for 90 seconds at 80 degrees Celsius at each location.
Study: NCT06646666

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: All-trans retinoic acid
Description: 10mg，tid，po (After apheresis and continued until post-infusion)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: zanubrutinib
Description: 160mg，bid，po (prior to apheresis and continued until post-infusion)

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: radiotherapy
Description: If the patient's specific lesions are suitable for radiotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAR-T
Description: CAR-T cell therapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 inhibitor
Description: IV 200 mg on D1, Q3W
Study: NCT05269264

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessor A (first measurement): measurement methods and questionnaires for the assessment of LLL
Description: pitting test at the level of the foot, leg and midline region; skinfold test at the level of the foot, leg and midline region; skin hardness test at the level of the foot, leg and midline region; measurement with MoistureMeterD at the level of the foot, leg and midline region; measurement with SkinFibroMeter at the level of the foot, leg and midline region; circumference measurements at the level of the leg and midline region; perometry at the level of the leg; water displacement measurement at the level of the foot; measurements with bio-impedance spectroscopy/analysis devices at the level of the lower limbs and a questionnaire regarding skin integrity (ICC compression questionnaire) that should be completed by the therapist and a self-reported disease-specific quality of life questionnaire (Lymph-ICF-LL) that is completed by the patient at the end of this evaluation
Study: NCT06165510

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Endocardial Catheter Ablation
Description: Standard percutaneous endocardial catheter ablation of atrial fibrillation
Study: NCT05854277

Intervention type: OTHER
Group type: OTHER
Intervention: educational video
Description: To explain the novel score, a six-minute instructional video was compiled and available to watch, as well as an online tool on the GIEQs website that could be used to grade the image-sets using the score.
Study: NCT05412069

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fecobionics
Description: Fecobionics is a novel device to be inserted through the anal canal into rectum for studying defecation. Anorectal manometry, balloon expulsion test, and anal ultrasonography will be used as reference.
Study: NCT05265169

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microwave ablation
Description: Microwave ablation of colorectal liver metastases (CLM)
Study: NCT05607784

Intervention type: BEHAVIORAL
Intervention: Formative Research- Content Translation
Description: This formative research includes brainstorming translation of content and reviewing wireframe prototypes generated from this process. It also includes attending to cultural, developmental, and gender considerations.~The design development cycles will begin with advisory focus group feedback about how the existing activities convey the content (i.e., what and how they are learning). They will advise on activity design for the remaining content (sexual health and content connecting this with ER) to ensure these are engaging, appropriate, and informative. They will also provide perspectives about design, structure, navigability, and approach

Intervention type: BEHAVIORAL
Intervention: Formative Research- Content Translation
Description: This formative research includes brainstorming translation of content and reviewing wireframe prototypes generated from this process. It also includes attending to cultural, developmental, and gender considerations.~The design development cycles will begin with advisory focus group feedback about how the existing activities convey the content (i.e., what and how they are learning). They will advise on activity design for the remaining content (sexual health and content connecting this with ER) to ensure these are engaging, appropriate, and informative. They will also provide perspectives about design, structure, navigability, and approach

Intervention type: BEHAVIORAL
Intervention: Formative Research- Content Feedback and Acceptability
Description: This formative research includes providing feedback on the proposed content and ensure contextual acceptability in schools.~The design development cycles will begin with advisory focus group feedback about how the existing activities convey the content (i.e., what and how they are learning). They will advise on activity design for the remaining content (sexual health and content connecting this with ER) to ensure these are engaging, appropriate, and informative. They will also provide perspectives about design, structure, navigability, and approach
Study: NCT04429945

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Virtual Reality Headset with Virtual Reality Applications
Study: NCT04671862

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photobiomodulation
Description: Parameters: combined 633nm and 870 nm @1000mW~* 1 Treatment 4J continuous prior to RT. (Within 14 days of RT start)~* 3 treatments weekly during RT (6 J at 12 Hz, 80% duty cycle)
Study: NCT05556954

Intervention type: PROCEDURE
Intervention: Wound debridement
Description: Participant that are having usual care visits for management of diabetic foot ulcers will be enrolled into this study. The procedure is done as part of standard of care. Tissue from the samples will be analyzed for this study.~Aliquoting and Deoxyribonucleic acid (DNA) extraction will be done on the specimens. Bacterial DNA from biospecimens will be isolated, quantified, amplified, and sequenced.

Intervention type: PROCEDURE
Intervention: Wound debridement
Description: Participant that are having usual care visits for management of diabetic foot ulcers will be enrolled into this study. The procedure is done as part of standard of care. Tissue from the samples will be analyzed for this study.~Aliquoting and Deoxyribonucleic acid (DNA) extraction will be done on the specimens. Bacterial DNA from biospecimens will be isolated, quantified, amplified, and sequenced.
Study: NCT05357781

Intervention type: DIAGNOSTIC_TEST
Intervention: Laboratory test
Description: Frequency of fatigue (defined as Fatigue Scala for Motor and Cognitive Function (FSMC) total ≥ 43 points) in MS patients with IgG-deficiency

Intervention type: DIAGNOSTIC_TEST
Intervention: Laboratory test
Description: Frequency of fatigue (defined as Fatigue Scala for Motor and Cognitive Function (FSMC) total ≥ 43 points) in MS patients with IgG-deficiency
Study: NCT05066087

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DAHLIA treatment
Description: 6 weeks; CBT/ ACT/ process-based treatment; micro-learning format with 4 digital micro-sessions per week; exposure as the core process; guidance to be OPEN, AWARE, ACTIVE; weekly contact with therapist; booster sessions after 2- and 4 months;

Intervention type: OTHER
Group type: OTHER
Intervention: Treatment as usual
Description: Usual pain treatment; defined post-hoc based on what patients receive
Study: NCT05392634

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meropenem 1000 mg
Description: Group B: prolonged antibiotic prophylaxis \>72 hours (5 days) from the moment of the skin incision in accordance with the selected clinic drug + correction of the appointment based on clinical events after 5 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin+clavulanic acid 1200 mg or Cefuroksim 1500mg
Description: Group A: antibiotic prophylaxis within 24 hours from the moment of skin incision according to local clinical practice;
Study: NCT05198232

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Zumba High Tempo
Description: The Zumba high tempo group will complete a 10-week (2x a week; 60 minutes per session) virtual adapted aerobic dance intervention (adapted Zumba®). Each session will consist of: a warm-up (3-5 minutes), 5-6 songs with instruction (40 minutes), and a cool down (5 minutes) for a total of about 60 minutes including rest/water breaks and time to transition. The only difference between the two adapted Zumba® programs will be the speed at which the songs will be played and the number of times through each song. The songs for the high-tempo group will be played at full speed; the songs in the high-tempo group will be repeated to ensure an equal amount of time moving for both groups. All sessions will be video recorded and examined for fidelity. This group will complete pre-test, post-test, and a 4-week follow-up.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Zumba Low Tempo
Description: The Zumba low tempo group will complete a 10-week (2x a week; 60 minutes per session) virtual adapted aerobic dance intervention (adapted Zumba®). Each session will consist of: a warm-up (3-5 minutes), 5-6 songs with instruction (40 minutes), and a cool down (5 minutes) for a total of about 60 minutes including rest/water breaks and time to transition. The only difference between the two adapted Zumba® programs will be the speed at which the songs will be played and the number of times through each song. The songs for the low-tempo group will be set to three-fourths speed. All sessions will be video recorded and examined for fidelity. This group will complete pre-test, post-test, and a 4-week follow-up.
Study: NCT06146465

Intervention type: OTHER
Intervention: speciality
Description: Not

Intervention type: OTHER
Intervention: speciality
Description: Not
Study: NCT05772767

Intervention type: OTHER
Group type: OTHER
Intervention: Biological sample collection
Description: Collection of tumor tissue and blood for stem cell culture and organoids generation.

Intervention type: OTHER
Group type: OTHER
Intervention: Dissecting ciliogenesis players
Description: Assessment of cilium-related transcriptome in glioblastoma stem cells. Modulation of cilium-related genes and administration of cilium-targeted drugs to glioblastoma stem cells in vitro and ex vivo in glioblastoma brain organoids.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Validating ciliogenesis players
Description: Cilium-related signature will be studied in tumor tissue to evaluate its prognostic role.
Study: NCT05062928

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual coach
Description: This group will be trained and assessed by the virtual coach.
Study: NCT04700306

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sophrology
Description: Patient must make 8 visits with interviews and questionnaires, including 7 visits with a session of sophrology.
Study: NCT05441930

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levofloxacin Ocular Implant
Description: Levofloxacin Ocular Implant an implant that delivers a bolus dose of levofloxacin and a constant daily dose for a further 5-7 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Commercially available topical medications as per LEVO-CS102 Surgical Therapy Procedure.