TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04181606

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline infusion
Description: Saline will be rate/volume matched to the calculated esmolol dose.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pre exercise baseline
Description: Subject rests quietly while drug infusion begins (3 min loading dose followed by 10 min of maintenance dose) until heart rate and blood pressure stabilize.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Pre exercise baseline
Description: Subject rests quietly while drug infusion begins (3 min loading dose followed by 10 min of maintenance dose) until heart rate and blood pressure stabilize.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isometric handgrip exercise
Description: The subject will grip at 40% of their maximum and maintain that grip for 90 seconds. Once at rest and once during heavy intensity cycling.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Isometric handgrip exercise
Description: The subject will grip at 40% of their maximum and maintain that grip for 90 seconds. Once at rest and once during heavy intensity cycling.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Semi-recumbent cycling
Description: Subjects will pedal for 2-4 minutes at a very light intensity (20W), followed immediately by 5 minutes at a moderate intensity (at a workload intended to elicit 85% of the oxygen consumption observed at the lactate threshold), and 5 minutes of cycling at a heavy intensity (at a workload estimated to elicit oxygen consumption half way between those observed at the lactate threshold and respiratory compensation point). Subjects will then continue cycling at the heavy intensity for 90 seconds while performing isometric handgrip exercise.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Semi-recumbent cycling
Description: Subjects will pedal for 2-4 minutes at a very light intensity (20W), followed immediately by 5 minutes at a moderate intensity (at a workload intended to elicit 85% of the oxygen consumption observed at the lactate threshold), and 5 minutes of cycling at a heavy intensity (at a workload estimated to elicit oxygen consumption half way between those observed at the lactate threshold and respiratory compensation point). Subjects will then continue cycling at the heavy intensity for 90 seconds while performing isometric handgrip exercise.
Study: NCT05727618

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pituitrin
Description: The specification of posterior pituitary injection is 1ml/6U, diluted with normal saline to 0.5u/ml, and injected by intravenous pump at the rate of 0.04u/ (kg · h).
Study: NCT05841342

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05727618

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: Intravenous infusion of normal saline at the same dose and speed
Study: NCT04935112

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famotidine
Description: 40 mg PO 2 hrs after sitravatinib in Period 2 of Group 2
Study: NCT04798209

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 14C-ACT-777991 microtracer (MAD - ADME)
Description: Single dose of 14C-ACT-777991 microtracer, oral solution..

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microtracer matching placebo (MAD - ADME)
Description: Single dose of 14C-ACT-777991 microtracer matching placebo, oral solution.
Study: NCT05175794

Intervention type: DIAGNOSTIC_TEST
Intervention: Xpert® MTB/XDR
Description: The Xpert MTB/XDR Assay, performed on the GeneXpert Instrument Systems, is a nested real-time polymerase chain reaction(PCR) in vitro diagnostic test for the detection of extensively drug resistant (XDR) Mycobacterium tuberculosis (MTB) complex DNA in unprocessed sputum samples or concentrated sediments prepared from sputum. In specimens where MTB is detected, the Xpert MTB/XDR Assay can also detect isoniazid (INH) resistance associated mutations in the katG and fabG1 genes, oxyRahpC intergenic region and inhA promoter; ethionamide (ETH) resistance associated with inhA promoter mutations only; fluoroquinolone (FLQ) resistance associated mutations in the gyrA and gyrB quinolone resistance determining regions (QRDR); and second line injectable drug (SLID) associated mutations in the rrs gene and the eis promoter region.

Intervention type: DIAGNOSTIC_TEST
Intervention: Xpert® MTB/XDR
Description: The Xpert MTB/XDR Assay, performed on the GeneXpert Instrument Systems, is a nested real-time polymerase chain reaction(PCR) in vitro diagnostic test for the detection of extensively drug resistant (XDR) Mycobacterium tuberculosis (MTB) complex DNA in unprocessed sputum samples or concentrated sediments prepared from sputum. In specimens where MTB is detected, the Xpert MTB/XDR Assay can also detect isoniazid (INH) resistance associated mutations in the katG and fabG1 genes, oxyRahpC intergenic region and inhA promoter; ethionamide (ETH) resistance associated with inhA promoter mutations only; fluoroquinolone (FLQ) resistance associated mutations in the gyrA and gyrB quinolone resistance determining regions (QRDR); and second line injectable drug (SLID) associated mutations in the rrs gene and the eis promoter region.
Study: NCT06505096

Intervention type: PROCEDURE
Intervention: cataract surgery
Description: Phaco+IOL implention

Intervention type: PROCEDURE
Intervention: cataract surgery
Description: Phaco+IOL implention

Intervention type: PROCEDURE
Intervention: cataract surgery
Description: Phaco+IOL implention
Study: NCT05996809

Intervention type: DEVICE
Intervention: Coseal
Description: Adhesion reduction
Study: NCT05441956

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TGRX-326
Description: Participants are given TGRX-326 tablets orally at one of the dose levels as pre-determined.
Study: NCT05712174

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18]F-PSMA-1007
Description: \[18\]F-PSMA-1007 is a diagnostic radiopharmaceutical for use with PET/CT or PET/MRI scanning to diagnose prostate cancer.
Study: NCT04667585

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: De-escalated radiation dose
Description: Reduced dose of radiation applied to remaining radiation therapy when favorable interim PET-CT signature is produced

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Standard radiation dose
Description: Standard dose of radiation applied to remaining radiation therapy when favorable PET-CT signature is not produced

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)-Computed Tomography (CT)
Description: The CT scan - also called computerized tomography or just CT - combines a series of X-ray views taken from many different angles to produce cross-sectional images of the bones and soft tissues inside the body. CT scans in planning radiation therapy are standard of care. A PET is a highly specialized imaging technique that uses short-lived radioactive substances (such as FDG a simple sugar labeled with a radioactive atom) to produce three-dimensional colored images of those substances functioning within the body. These images are called PET scans and the technique is termed PET scanning. PET scanning provides information about the body's chemistry not available through other procedures. Unlike CT or MRI (magnetic resonance imaging), techniques that look at anatomy or body form, PET studies metabolic activity or body function.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)-Computed Tomography (CT)
Description: The CT scan - also called computerized tomography or just CT - combines a series of X-ray views taken from many different angles to produce cross-sectional images of the bones and soft tissues inside the body. CT scans in planning radiation therapy are standard of care. A PET is a highly specialized imaging technique that uses short-lived radioactive substances (such as FDG a simple sugar labeled with a radioactive atom) to produce three-dimensional colored images of those substances functioning within the body. These images are called PET scans and the technique is termed PET scanning. PET scanning provides information about the body's chemistry not available through other procedures. Unlike CT or MRI (magnetic resonance imaging), techniques that look at anatomy or body form, PET studies metabolic activity or body function.
Study: NCT04977076

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Uninterrupted NOAC use
Description: Continuing NOAC use in advance of elective CAG or PCI.
Study: NCT02918708

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Synflorix
Description: 10-valent pneumococcal conjugate vaccine

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevenar13
Description: 13-valent pneumococcal conjugate vaccine

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevenar13
Description: 13-valent pneumococcal conjugate vaccine
Study: NCT05527886

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AAROM
Description: AAROM with knee to wall exercise, 3x30 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AAROM
Description: AAROM with knee to wall exercise, 3x30 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AAROM
Description: AAROM with knee to wall exercise, 3x30 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Slow Load
Description: Single leg heel raise, 3x10 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Slow Load
Description: Single leg heel raise, 3x10 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Slow Load
Description: Single leg heel raise, 3x10 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plyometric
Description: Double leg 5 inch wall hops, 3x10 sec

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plyometric
Description: Double leg 5 inch wall hops, 3x10 sec

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plyometric
Description: Double leg 5 inch wall hops, 3x10 sec
Study: NCT06014281

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SOS Meditation
Description: Focused-attention meditation technique will be used to train participants, specifically the SOS meditation technique. The SOS meditation technique is an easy-to-learn approach where participants are instructed to dissociate their attention from physical awareness, thoughts, and emotions by mentally slowly repeating a calming word or phrase (chosen by the participant themselves).~SOS Meditation Instructions:~* Close your eyes very gently, in a relaxed way, as you do when we go to sleep~* Your attention should be fully alert. Try not to put any strain on your eyes or try to look up.~* Focus your eyes about eight to ten inches into the field of darkness in front of you on the horizontal plane~* Mentally repeat the (chosen) calming word~* Sit lovingly and calmly to see what comes up, as if you were watching a movie screen and waiting to see what appears on it.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SOS Meditation
Description: Focused-attention meditation technique will be used to train participants, specifically the SOS meditation technique. The SOS meditation technique is an easy-to-learn approach where participants are instructed to dissociate their attention from physical awareness, thoughts, and emotions by mentally slowly repeating a calming word or phrase (chosen by the participant themselves).~SOS Meditation Instructions:~* Close your eyes very gently, in a relaxed way, as you do when we go to sleep~* Your attention should be fully alert. Try not to put any strain on your eyes or try to look up.~* Focus your eyes about eight to ten inches into the field of darkness in front of you on the horizontal plane~* Mentally repeat the (chosen) calming word~* Sit lovingly and calmly to see what comes up, as if you were watching a movie screen and waiting to see what appears on it.
Study: NCT06098664

Intervention type: DIAGNOSTIC_TEST
Intervention: AI-enabled ECG score for Atrial Fibrillation (DNN score)
Description: A 12-lead ECG, performed within 24 hours before the Pulmonary Vein Isolation (PVI) procedure, will be used to calculate the DNN score.~(DNN score details: https://doi.org/10.1016/j.jacep.2023.04.008)

Intervention type: DIAGNOSTIC_TEST
Intervention: AI-enabled ECG score for Atrial Fibrillation (DNN score)
Description: A 12-lead ECG, performed within 24 hours before the Pulmonary Vein Isolation (PVI) procedure, will be used to calculate the DNN score.~(DNN score details: https://doi.org/10.1016/j.jacep.2023.04.008)

Intervention type: DIAGNOSTIC_TEST
Intervention: AI-enabled ECG score for Atrial Fibrillation (DNN score)
Description: A 12-lead ECG, performed within 24 hours before the Pulmonary Vein Isolation (PVI) procedure, will be used to calculate the DNN score.~(DNN score details: https://doi.org/10.1016/j.jacep.2023.04.008)

Intervention type: DIAGNOSTIC_TEST
Intervention: Atrial voltage map in sinus rhythm
Description: An atrial voltage map will be constructed prior to the PVI procedure.

Intervention type: DIAGNOSTIC_TEST
Intervention: Atrial voltage map in sinus rhythm
Description: An atrial voltage map will be constructed prior to the PVI procedure.

Intervention type: DIAGNOSTIC_TEST
Intervention: Atrial voltage map in sinus rhythm
Description: An atrial voltage map will be constructed prior to the PVI procedure.
Study: NCT06282601

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audiogram
Description: Tonal and vocal free-field without lip-reading

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Musical priming for the syntax test
Description: Listening to music with a regular or irregular rhythm, then judging the grammaticality of 2x6 blocks of French sentences interrupted by a pause, each block presenting 4 sentences including 2 grammatically correct sentences and 2 grammatically incorrect sentences. The sentences are pronounced by a French female voice at a natural rhythm and comfortable volume.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Test MMSE
Description: test to assess a person's cognitive functions and memory capacity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Barcelona Music Reward Questionnaire
Description: 20 questions exploring 5 main facets of the musical reward experience, with 4 items for each of the 5 facets, for which participants indicate the level of agreement using a 5-level scale, ranging from strongly disagree to strongly agree.
Study: NCT05035589

Intervention type: DRUG
Intervention: Tocilizumab
Description: Tocilizumab administered at a dose of 8mg/kg up to a maximum of 800mg
Study: NCT05288140

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: use of diary
Description: a diary is made for the experimental group where the events and events during the period of sedation and intubation are explained
Study: NCT04977076

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Interrupted NOAC use
Description: Usual care, interruption of NOAC prior to procedure.
Study: NCT05637749

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Medical serious game intervention (educational)
Description: Medical serious game designed to facilitate the rehearsal of diabetes management knowledge. Players are presented with a colony of individuals, all of whom have some form of diabetes, and are tasked to manage food, insulin, and medication intake throughout the day. The intervention may be played with a facilitator.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical serious game intervention (educational)
Description: Medical serious game designed to facilitate the rehearsal of diabetes management knowledge. Players are presented with a colony of individuals, all of whom have some form of diabetes, and are tasked to manage food, insulin, and medication intake throughout the day. The intervention may be played alone.
Study: NCT06231927

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Skills for Life Adjustment and Resilience (SOLAR) program
Description: The SOLAR program is a 5-session intervention program that aims to introduce participants necessary recovery skills after a traumatic event resulting in a subclinical distress. During the program, participants will be given workbooks including the topics for skill development for recovery and adjustment. At each session, they will discuss these topics with the study coaches.
Study: NCT05365984

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: end tidal carbon monoxide corrected for ambient carbon monoxide （ETCOc）
Description: The measurement of end tidal carbon monoxide corrected for ambient carbon monoxide （ETCOc）is conducted in the process of risk evaluation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet Plus technology
Description: The Internet Plus technology is applied in the process of follow-up management.
Study: NCT05633290

Intervention type: DIAGNOSTIC_TEST
Intervention: CMR
Description: CMR Imaging 6-10 weeks post hospital discharge.

Intervention type: DIAGNOSTIC_TEST
Intervention: hs-troponin
Description: Biomarker of myocardial injury

Intervention type: DIAGNOSTIC_TEST
Intervention: NT-pro BNP
Description: Biomarker for heart failure

Intervention type: DIAGNOSTIC_TEST
Intervention: CRP
Description: Acute phase inflammatory marker

Intervention type: DIAGNOSTIC_TEST
Intervention: IL1-B
Description: Inflammatory biomarker
Study: NCT04708938

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High voltage electrical stimulation+exercise therapy
Description: The effect of high voltage electrical stimulation on temporomandibular disorders

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise therapy
Description: The effect of high voltage electrical stimulation on temporomandibular disorders
Study: NCT05633290

Intervention type: DIAGNOSTIC_TEST
Intervention: IL-6
Description: Inflammatory Biomarker

Intervention type: DIAGNOSTIC_TEST
Intervention: IL-10
Description: Inflammatory Biomarker
Study: NCT06001554

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interaction Competencies with Children - for Teachers (ICC-T)
Description: Core training components include teacher-student interaction, maltreatment prevention, effective discipline strategies, identifying and supporting burdened students and implementation of the training materials into the school setting
Study: NCT04322747

Intervention type: DIAGNOSTIC_TEST
Intervention: Distortion product otoacoustic emissions (DPOAE)
Description: Audiometry for extended high frequencies, DPOAE, and, ECochG measurements will be collected before and after skull-based surgeries.
Study: NCT05190380

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HIGH INTENSITY PROGRESSIVE RESISTED EXERCISE
Description: Intervention:Leg presses, knee extension, hip adduction and hip abduction exercises will be performed by patients. There will be a warm up sets for 1 repetition maximum with 2 min gap between both sets (leg press + knee extension exercises) (hip abduction and hip adduction) patients will ask to perform.~Both groups will receive routine physical therapy (Tens, Hot pack, Deep friction massage) in addition with experimental interventions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LOW INTENSITY PROGRESSIVE RESISTED EXERCISE
Description: Intervention:Leg presses, knee extension, hip adduction and hip abduction exercises will be performed by patients. There will be a warm up sets for 1 repetition maximum with 2 min gap between both sets (leg press + knee extension exercises) (hip abduction and hip adduction) patients will ask to perform.~Both groups will receive routine physical therapy (Tens, Hot pack, Deep friction massage) in addition with experimental interventions
Study: NCT05633290

Intervention type: DIAGNOSTIC_TEST
Intervention: TNF-alpha
Description: Inflammatory Biomarker
Study: NCT05750901

Intervention type: DEVICE
Group type: OTHER
Intervention: Fractional ablative laser
Description: Fractional ablative laser used for treatment for skin laxity and tightening
Study: NCT05555914

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurostimulation
Description: Implantation of 3 multicontact cuff electrodes in the upper limb of patients with tetraplegia and control of the stimulation by contralateral shoulder movements
Study: NCT05157178

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Covid-19 (recombinante) vaccine
Description: Administration of the Covid-19 (recombinante) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Covid-19 (recombinante) vaccine
Description: Administration of the Covid-19 (recombinante) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Covid-19 (recombinante) vaccine
Description: Administration of the Covid-19 (recombinante) vaccine
Study: NCT05257343

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Liquid Placebo Supplementation
Description: 8-weeks of supplementing with a visually identical liquid placebo supplement.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Liquid Iron Supplement (Blood Builder ®)
Description: 8-weeks of supplementing with a liquid iron supplement (Blood Builder ®)
Study: NCT05403229

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topiramate
Description: The topiramate arm receives additional oral topiramate for 6 weeks. The dose of topiramate is started from 25mg orally daily with the weekly escalation of 25mg to a maximum of 100mg.
Study: NCT06100354

Intervention type: OTHER
Intervention: Answering preference
Description: Patients will answer a questionnaire with two possible choices describing several scenario of used of customized and connected prosthesis
Study: NCT05575349

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mandala coloring
Description: Participants will be asked to choose the pages they want from 12 colored felt-tip pen paint sets and 12 mandala coloring pages given to each participant by the researcher for 6 weeks, 1 days a week, at any time of the day and for an average of 20-30 minutes each time, and paint them in the colors they want.
Study: NCT05792683

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: lumbar drain
Description: Patient will be placed in the lateral decubitus position; catheter will be inserted by using a Tuohy needle in the interspinous area of lumbar spine. The LD catheter will reach the lumbar subarachnoid space.The remaining part of the drainage kit will be placed along the back of the patient. The catheter insertion site will be sutured and treated with povidone-iodine ointment. Sterile drape will be used to cover the entire external part of the LD.~The CSF will be collected within the closed beg. CSF drainage through LD will be around 10 ml per hour or 200-250 ml/day.
Study: NCT05403229

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Systemic Steroids
Description: Both groups receive a systemic steroid with/without intratympanic steroids as the standard treatment of SSNHL.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Systemic Steroids
Description: Both groups receive a systemic steroid with/without intratympanic steroids as the standard treatment of SSNHL.