TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04929795

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rhythmic auditory stimulation (RAS)
Description: The song named 'Sign of The Times' is played and recorded by the research personnel beforehand. The beat of the song will serve as RAS. The computer software Audacity will be used to adjust tempi of RAS. Before intervention, the participant is required to execute the movement task without the aid of RAS as quickly as possible for 30 seconds, so that we obtain his/her baseline movement tempo. For each 40-minute training session in the first training week, three RAS tempi will be provided for the first, second, and last 10 minutes with a five-minute break in between: normal (100% of the baseline tempo), quick (105% of the baseline tempo), and fast (110% of the baseline tempo). With each training week, the three RAS tempi will be increased by 5%. Participants in the experimental groups are required to use their right hand to pick up beads from source bowls to the target bowl when listening to the song. The 3-week intervention program will include 21 40-minute daily training sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rhythmic auditory stimulation (RAS)
Description: The song named 'Sign of The Times' is played and recorded by the research personnel beforehand. The beat of the song will serve as RAS. The computer software Audacity will be used to adjust tempi of RAS. Before intervention, the participant is required to execute the movement task without the aid of RAS as quickly as possible for 30 seconds, so that we obtain his/her baseline movement tempo. For each 40-minute training session in the first training week, three RAS tempi will be provided for the first, second, and last 10 minutes with a five-minute break in between: normal (100% of the baseline tempo), quick (105% of the baseline tempo), and fast (110% of the baseline tempo). With each training week, the three RAS tempi will be increased by 5%. Participants in the experimental groups are required to use their right hand to pick up beads from source bowls to the target bowl when listening to the song. The 3-week intervention program will include 21 40-minute daily training sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: no RAS
Description: The training protocol will be the same as that used in the experimental group except the lack of RAS during execution of the movement task.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: no RAS
Description: The training protocol will be the same as that used in the experimental group except the lack of RAS during execution of the movement task.
Study: NCT05927623

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multifaceted Virtual Fracture Prevention Program
Description: * Personalized exercise prescription: Comprised of muscle strengthening and balance exercises to perform three times a week, delivered and monitored remotely via the MisterFit app, a branded version of the secure commercially available Wibbi app (wibbi.com) and monthly virtual exercise consultations.~* Virtual nutrition counseling from a registered dietitian in months 2, 4 and 6: to encourage participants to meet daily targets for calcium and vitamin D (preferably from diet), and protein intake to support muscle accretion and target weight maintenance~* Virtual interactive information sessions in month 4 and 8: to education participants on topics identified as important by the Misterfit patient partner advisory committee.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Attention Control
Description: * Encouraged to meet the 24-Hour Movement Guidelines for adults aged 65 years or older (https://csepguidelines.ca) with telephone contacts at the same frequency that the Misterfit online group receives virtual exercise consultations~* Nutritional fact sheets: sent by e-mail at the same frequency that the Misterfit online group meets with the research dietitian.~* Educational fact sheets: sent by e-mail at the same frequency that the Misterfit Online group has virtual interactive information sessions
Study: NCT05208125

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.HTI at week 0, ConM SOSIP.v7 at weeks 4, 12 and 28, and MVA.HTI at week 22 (CSSMS).
Description: Intramuscular administration of 1 x ChAdOx1.HTI (5x1010 Vp), 3 x ConM SOSIP.v7 (100μg) adjuvanted with MPLA liposomes (500μg), and 1 x MVA.HTI (2x108pfu)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline solution
Description: Intramuscular administration of normal saline solution
Study: NCT05823922

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Clinician Delivered CBT
Description: Clinicians teach cognitive behavioral therapy (CBT) techniques including emotion monitoring, cognitive restructuring, mindfulness, and exposure to help individuals with anxiety and depression. Participants will attend weekly sessions with their clinician for 6 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Clinician Delivered CBT
Description: Clinicians teach cognitive behavioral therapy (CBT) techniques including emotion monitoring, cognitive restructuring, mindfulness, and exposure to help individuals with anxiety and depression. Participants will attend weekly sessions with their clinician for 6 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supplemental MAYA App
Description: The Maya app teaches cognitive behavioral therapy (CBT) techniques including emotion monitoring, cognitive restructuring, mindfulness, and exposure to help individuals with anxiety.~Participants will attend weekly sessions with their clinician as well as using the MAYA application for at least 20 minutes twice a week
Study: NCT04818216

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsule containing inert ingredient

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotinamide riboside
Description: 250 mg Nicotinamide riboside capsules
Study: NCT05103618

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: [F-18] Fluorodopa Positron Emission Tomography
Description: Subjects will receive FDOPA imaging at baseline and 2-3 months after practicing the OM Meditation for evaluation of the dopamine function, \[F-18\] Fluorodopa (FDOPA), dose (5-10 mCi, ± 20%) will be injected intravenously into an antecubital vein. In accordance with the standard imaging protocol for FDOPA; subjects will be pre-medicated with 200 mg of carbidopa orally approximately one hour prior to injection.

Intervention type: DRUG
Group type: OTHER
Intervention: [F-18] Fluorodopa Positron Emission Tomography
Description: Subjects will receive FDOPA imaging at baseline and 2-3 months after practicing the OM Meditation for evaluation of the dopamine function, \[F-18\] Fluorodopa (FDOPA), dose (5-10 mCi, ± 20%) will be injected intravenously into an antecubital vein. In accordance with the standard imaging protocol for FDOPA; subjects will be pre-medicated with 200 mg of carbidopa orally approximately one hour prior to injection.
Study: NCT05477251

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: lobectomy
Description: lobectomy for GGOs located in hilar regions
Study: NCT03324867

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Regular insulin
Description: 40 IU of Humulin-R to be administered via nose using metered nasal dispenser prior to surgery, and up to 7 days after surgery.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline Flush, 0.9% Injectable Solution
Description: Placebo: Normal Saline to be administered via nose using metered nasal dispenser prior to surgery, and up to 7 days after surgery
Study: NCT04691245

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D US
Description: 3D US guided access to femoral artery

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 2D US
Description: 2D US guided access to femoral artery
Study: NCT05780801

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Allogeneic Microbiota in Glycerol (10%) (AMG)
Description: Participants with positive MDRO cultures will receive MT instilled via a functional feeding tube when in place or rectal enema (when a functional feeding tube is not present) with the rate adjusted to the recipient's clinical status and infusion tolerance.
Study: NCT06386978

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transverse Facia Plane Block (TAP Block)
Description: Spinal Anesthesia + TAP block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transversalis Facia Plane Block (TFP Block)
Description: Spinal Anesthesia + TFP block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Spinal anesthesia + No block
Study: NCT05072860

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical tranexamic acid
Description: temporary uterine packing with gauze of the dimensions soaked with 2 gm tranexamic diluted in 60ml saline acid

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: : normal saline
Description: temporary uterine packing with gauze of the dimensions soaked with placebo to 2 gm tranexamic diluted in 60ml saline acid
Study: NCT04963855

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: GT300
Description: SIngle oral dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Microcrystalline cellulose
Description: placebo
Study: NCT06027619

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical aminolevulinate (10% ALA gel)
Description: 10% ALA gel to the entire face, without occlusion, followed by a prespecified incubation period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical aminolevulinate (10% ALA gel)
Description: 10% ALA gel to the entire face, without occlusion, followed by a prespecified incubation period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical aminolevulinate (10% ALA gel)
Description: 10% ALA gel to the entire face, without occlusion, followed by a prespecified incubation period

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Red light illumination
Description: Illumination of red light of narrow spectrum of 635 nm with a light dose of approximately 37 J/cm2

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Red light illumination
Description: Illumination of red light of narrow spectrum of 635 nm with a light dose of approximately 37 J/cm2

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Red light illumination
Description: Illumination of red light of narrow spectrum of 635 nm with a light dose of approximately 37 J/cm2
Study: NCT06129461

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Single-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy
Description: Participants in the intervention will learn acceptance-based strategies for reducing the adverse impact of food cravings on eating behaviors. Unlike control-based strategies, acceptance-based strategies do not attempt to change the content or frequency of thoughts; rather, they foster willingness to acknowledge and experience uncontrollable thoughts, urges, and emotions as what they are - nothing more, nothing less. Acceptance-based approaches have demonstrated efficacy in reducing the adverse impact of food cravings on eating behaviors in non-pregnant samples.
Study: NCT06225141

Intervention type: OTHER
Intervention: Clinical Data reuse
Description: Clinical Data reuse

Intervention type: OTHER
Intervention: Clinical Data reuse
Description: Clinical Data reuse
Study: NCT05004389

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI
Description: white matter integrity and brain structural connectivity metrics

Intervention type: DIAGNOSTIC_TEST
Intervention: blood draw
Description: post-stroke serum/plasma levels of BDNF, VEGF, IL-6, IL-10, CRP, TNFalpha, MMPs, IGF-1, cGP

Intervention type: OTHER
Intervention: Clinical assessments
Description: measures of strength, balance, and mobility
Study: NCT05126654

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Partially Hydrolyzed Guar Gum (PHGG)
Description: Partially Hydrolyzed Guar Gum 5 gram/day for 1 month

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Partially Hydrolyzed Guar Gum (PHGG)
Description: Partially Hydrolyzed Guar Gum 5 gram/day for 1 month
Study: NCT06019390

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Presage care
Description: A screening questionnaire completed by the family caregiver focused on functional and clinical autonomy of the patient (ie, activities of daily life), possible medical symptoms (eg, fatigue, falls, and pain), changes in behavior (eg, recognition and aggressiveness), and communication with relative or their surroundings.
Study: NCT06456411

Intervention type: PROCEDURE
Intervention: Functional Near-Infrared Spectroscopy
Description: Undergo fNIRS

Intervention type: PROCEDURE
Intervention: Functional Near-Infrared Spectroscopy
Description: Undergo fNIRS

Intervention type: PROCEDURE
Intervention: Functional Near-Infrared Spectroscopy
Description: Undergo fNIRS

Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Intervention: Virtual Technology Intervention
Description: Undergo relaxation period using VR
Study: NCT05178680

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: relaxation session combining music and soft light
Description: The caregiver will install a device consisting of a light bubble column, a multicolored light projector, and relaxing music chosen by the patient from a proposed panel. This session will last 30 minutes the day after the surgery
Study: NCT05692986

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
Description: This is a randomized control trial that will compare chlorhexidine vaginal prep with iodine vaginal prep. Our primary outcome will be assessed using a vaginal swab test to look for aerobic and anaerobic cultures. Positive cultures will be defined as colony forming count of \>5000cfu. All patients will receive preoperative antibiotics. Patients will receive a vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery was completed.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
Description: This is a randomized control trial that will compare chlorhexidine vaginal prep with iodine vaginal prep. Our primary outcome will be assessed using a vaginal swab test to look for aerobic and anaerobic cultures. Positive cultures will be defined as colony forming count of \>5000cfu. All patients will receive preoperative antibiotics. Patients will receive a vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery was completed.
Study: NCT05906680

Intervention type: PROCEDURE
Intervention: Additional biopsies collection
Description: We will recruit only subjects (UC, CD and NO-UC/CD) scheduled for the endoscopy and biopsies-collection according to the usual clinical practice. During the endoscopy we will collect 6 additional biopsies.

Intervention type: PROCEDURE
Intervention: Additional biopsies collection
Description: We will recruit only subjects (UC, CD and NO-UC/CD) scheduled for the endoscopy and biopsies-collection according to the usual clinical practice. During the endoscopy we will collect 6 additional biopsies.

Intervention type: PROCEDURE
Intervention: Additional biopsies collection
Description: We will recruit only subjects (UC, CD and NO-UC/CD) scheduled for the endoscopy and biopsies-collection according to the usual clinical practice. During the endoscopy we will collect 6 additional biopsies.
Study: NCT05064501

Intervention type: DIAGNOSTIC_TEST
Intervention: spirometry
Description: Lung function test: pre and post bronchodilator spirometry

Intervention type: DIAGNOSTIC_TEST
Intervention: spirometry
Description: Lung function test: pre and post bronchodilator spirometry

Intervention type: OTHER
Intervention: Asthma control test
Description: Asthma control test

Intervention type: OTHER
Intervention: Asthma control test
Description: Asthma control test
Study: NCT06389344

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: Esketamine ( 50mg, dissolved in 50ml normal saline ) 0.3mg / kg will be infused intravenously at a constant speed within 30 min after tracheal intubation/pneumatectomy fixation.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: Same amount of normal saline will be infused intravenously at a constant speed within 30 min after tracheal intubation/pneumatectomy fixation.
Study: NCT05802472

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Polyphenolic beverage from extract of Vachellia farnesiana
Description: During Visit 2. A single infusion of the polyphenolic extract was administered orally. The dose (1.2 mg/kg body weight) of lyophilized extract, which was diluted in water, was calculated considering each participant's weight.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: During Visit 2. 250 ml of single potable water was administered orally.
Study: NCT06554782

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: manual u-shaped toothbrush
Description: manual u-shaped toothbrush with bristles angled 45 degrees to brush upper and lower teeth at the same time

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: manual u-shaped toothbrush
Description: manual u-shaped toothbrush with bristles angled 45 degrees to brush upper and lower teeth at the same time
Study: NCT05284500

Intervention type: PROCEDURE
Intervention: Pediatric cardiac surgery with cardiopulmonary bypass
Description: All patients undergoing pediatric cardiac surgery with cardiopulmonary bypass will be extracted from our database
Study: NCT04775355

Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo collection of stool and urine

Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Medical records are reviewed

Intervention type: OTHER
Intervention: Quality-of-Life Assessment
Description: Complete quality of life questionnaires

Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study: NCT05723692

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALTB-268
Description: monoclonal antibody

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: formulation buffer
Study: NCT05103618

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: OM Meditation
Description: Couple pairs will engage in OM Meditation together approximately 3-4 times a week approximately 2-3 months.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: OM Meditation
Description: Couple pairs will engage in OM Meditation together approximately 3-4 times a week approximately 2-3 months.
Study: NCT06541522

Intervention type: DEVICE
Group type: OTHER
Intervention: EIT
Description: Two PEEP titrations monitored by EIT will be performed, each with the electrode belt positioned at a different chest height (2nd intercostal space or 5th intercostal space). The order will be drawn at random.
Study: NCT05778526

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: There are a total of 12 training sessions for 3 weeks (4 sessions per week). Each session of the Social VR intervention lasts for a maximum of 20 minutes. The intervention contains three real-life virtual scenarios, including (1) a classroom and playground, (2) an MTR station and compartment, and (3) a supermarket and restaurant.
Study: NCT05509556

Intervention type: OTHER
Intervention: talocalcaneal angle measurement
Description: talocalcaneal angle measurement on lateral foot radiographs

Intervention type: OTHER
Intervention: talocalcaneal angle measurement
Description: talocalcaneal angle measurement on lateral foot radiographs
Study: NCT05961397

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: baxdrostat
Description: single oral dose of baxdrostat 10 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: baxdrostat
Description: single oral dose of baxdrostat 10 mg
Study: NCT06250933

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Postpartum Maternal Care and Premature Infant Care Training
Description: Intervention groups of women will receive a single-session intervention program in addition to their routine care.~The intervention, conducted in a single session, encompasses the provision of an educational program designed to enhance women's breastfeeding and maternal self-efficacy and mitigate the risk of postpartum depression.~During the educational phase, women will receive training on postpartum maternal care and premature infant care