TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05621538

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Realtime fMRI Neurofeedback - Active
Description: fMRI aided reinforcement of craving regulation

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TMS - Active
Description: rTMS to right dorsolateral prefrontal cortex to reduce craving

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TMS - Active
Description: rTMS to right dorsolateral prefrontal cortex to reduce craving

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Realtime fMRI Neurofeedback - Yoked Sham
Description: Display of feedback from other participant's sessions to serve as a sham for fMRI aided reinforcement of craving regulation

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Realtime fMRI Neurofeedback - Yoked Sham
Description: Display of feedback from other participant's sessions to serve as a sham for fMRI aided reinforcement of craving regulation

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TMS - Sham
Description: rTMS using placebo coil (no brain stimulation, emulates other features of active TMS), placed over right dorsolateral prefrontal cortex

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: TMS - Sham
Description: rTMS using placebo coil (no brain stimulation, emulates other features of active TMS), placed over right dorsolateral prefrontal cortex
Study: NCT05119894

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole LAI: Dose 4
Description: Cohort 4: Single Dose Intramuscular Injection:Brexpiprazole LAI Dose 4
Study: NCT06364800

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: γδ T cells
Description: Cells will be extracted from a healthy donor by apheresis, followed by ex-vivo expansion and activation. The ex-vivo expanded γδ T cells from donors will be adoptively transfused.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PD-1 monoclonal antibody
Description: Humanized programmed death receptor (PD-1) monoclonal antibody that binds to PD- and prevents binding of PD-1 with programed death ligands 1 (PD-L1) and PD-L2. It can function to activate cytotoxic T lymphocytes and inhibit tumor growth.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 monoclonal antibody
Description: Humanized programmed death receptor (PD-1) monoclonal antibody that binds to PD- and prevents binding of PD-1 with programed death ligands 1 (PD-L1) and PD-L2. It can function to activate cytotoxic T lymphocytes and inhibit tumor growth.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: targeted drugs
Description: Multi-target kinase inhibitors can act on VEGFR-1,VEGFR-2,VEGFR-3,FGFR1,PDGFR,cKit,Ret and other targets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: targeted drugs
Description: Multi-target kinase inhibitors can act on VEGFR-1,VEGFR-2,VEGFR-3,FGFR1,PDGFR,cKit,Ret and other targets.
Study: NCT04875234

Intervention type: DEVICE
Intervention: Clear-K Low Vision Aid Treatment
Description: A Clear-K Low Vision Aid Device is used to produce small corneal shape and refraction changes in order to redirect light onto functional areas of the retina.
Study: NCT06152133

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic core stability exercises
Description: exercises focused on trunk muscle strengthening, proprioception, selective movements of the trunk and pelvis muscle, and coordination, and will be carried out in supine, sitting on a stable surface and sitting on an unstable surface (ball). The exercise involves changes in the position of the body with or without resistance, aiming to improve strength, endurance, proprioception and coordination. Training is determined by the patient's ability to undertake easy exercises and progress to more challenging exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic core stability exercises
Description: exercises focused on trunk muscle strengthening, proprioception, selective movements of the trunk and pelvis muscle, and coordination, and will be carried out in supine, sitting on a stable surface and sitting on an unstable surface (ball). The exercise involves changes in the position of the body with or without resistance, aiming to improve strength, endurance, proprioception and coordination. Training is determined by the patient's ability to undertake easy exercises and progress to more challenging exercises.
Study: NCT05603468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: platelet rich plasma
Description: Platelet rich plasma group: after the surgery of rotator arthroscopic rotator cuff repair, 3ml PRP (LongTai Biological Company) was injected into the rotator cuff tear under the rotator arthroscope for a time. PRP production process: before anesthesia, 20ml arterial blood was drawn and injected into the PRP tube. The blood was fully oscillated in the tube, and then placed in a centrifuge with 1500g for 9min to remove excess plasma and make 5ml PRP. 3ml is used for injection and 2ml is used for quality control.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Corticosteroid
Description: Corticosteroid group: after the surgery of rotator cuff repair under arthroscopy, 1mL prednisone (MSD) + 2mL sodium hyaluronate (biochemical Industry Co., Ltd.) was injected under arthroscopy.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Normal saline
Study: NCT05933031

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegoprazan 50 mg Triple Therapy
Description: Tegoprazan 50 mg/Clarithromycin/ Amoxicillin BID peroral, 14 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegoprazan 100 mg Triple Therapy
Description: Tegoprazan 100 mg/Clarithromycin/ Amoxicillin BID peroral, 14 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lansoprazole Triple Therapy
Description: Lansoprazole/Clarithromycin/ Amoxicillin BID peroral, 14 days
Study: NCT05402280

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Sleep protocol
Description: To investigate the effect of a multicomponent sleep protocol on the quality of sleep hospitalized patients assessed both subjectively and objectively.
Study: NCT05847426

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Provision of standard audiological + fNIRS test results
Description: Infants with hearing loss will be tested using functional near-infrared spectroscopy (fNIRS) and a patented analysis algorithm to measure sound detection and discrimination. Their standard audiological test results will also be collected from their audiology service provider/s. Both sets of test results will be given to the participating audiologists in the experimental arm.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Provision of standard audiological test results only
Description: The provision of test results to the audiologist will be the same as in the experimental arm, but without the fNIRS test results included.
Study: NCT05582720

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional burger
Description: Participants initially randomized to this intervention arm will be provided with a total of 8 conventional burgers and will be asked to consume them twice weekly for 4 weeks. Conventional burgers will be produced by Hellenic Catering S.A. using standard procedures. Participants will also be instructed to maintain their usual dietary intake, physical activity level, prescribed medications and dietary supplements, as well as to refrain from any weight loss effort during the intervention. After a 2-week wash-out period (no burger consumption), participants will cross over to the other intervention arm.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vegan burger
Description: Participants initially randomized to this intervention arm will be provided with a total of 8 vegan burgers and will be asked to consume them twice weekly for 4 weeks. Vegan burgers will be produced by Hellenic Catering S.A. using novel technologies. Participants will also be instructed to maintain their usual dietary intake, physical activity level, prescribed medications and dietary supplements, as well as to refrain from any weight loss effort during the intervention. After a 2-week wash-out period (no burger consumption), participants will cross over to the other intervention arm.
Study: NCT06393348

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-7535
Description: HRS-7535

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-7535
Description: HRS-7535

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05750459

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artesunate
Description: Artesunate is a succinic ester of artemether.
Study: NCT06406309

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Power Down manipulation
Description: The Power Down is a bedtime manipulation protocol targeting elevated arousal level at bedtime due to a hypothesized effect of sensory over-responsivity (a common experience for children with ADHD). The Power Down incorporates sensory-based tools (gentle tactile pressure and auditory cues) to support nervous system regulation prior to attempting sleep onset. Caregivers will lead a nightly gentle massage with guided relaxation script just prior to the child trying to fall asleep during the 2-week intervention phase. The child will also wear a watch-like activity monitor (ActiGraph GT9x) for the 2 week period throughout the day and night to measure changes in sleep and activity patterns. Caregivers will complete daily diary questions in the morning and evening reporting their child's emotions and sleep timing.
Study: NCT05134181

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: sacroiliac joint injection
Description: Intervention will be done at complete aseptic conditions by ultrasound at frequency of 4-5 MHz patient in prone position. The ultrasound transducer will be oriented in a transverse orientation at the level of the sacral hiatus. Here the sacral cornuae are identified. Moving the transducer laterally from here, the lateral edge of the sacrum is now identified. This bony edge is~followed in a cephalad direction with the transducer maintained in a transverse orientation. A second bony contour, the ileum, is now identified. The cleft between both bony contours represented the sacroiliac joint. This will be found at 4.5 cm depth. Real-time imaging will be used to direct a 22G spinal needle into the SIJ, where 2% lidocaine and triamcinolone or methylprednisolone will be injected under direct vision.The needle will be removed, a sterile dressing will be applied
Study: NCT06482866

Intervention type: OTHER
Intervention: Cottle's septoplasty and radiocoagulation conchoplasty
Description: Cottle's septoplasty and radiocoagulation conchoplasty Study group - added nasal splits; Control group - nasal splits weren't used.
Study: NCT04618874

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Rapid on-site evaluation
Description: Rapid on site evaluation performed with an MGG quick stain (Bio-Optica, Milano, Italy).
Study: NCT06490107

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab combined with S-1
Description: The treatment regimen for this study is as follows:~First 8 cycles of adjuvant therapy: Durvalumab 1500mg, (Day 1, IV, Q3W) and S-1 40mg/m2 (Day1-14, BID, Q3W), up to 8 cycles.~Maintenance therapy stage(6 cycles)：If the patients do not experience disease recurrence or intolerance after first 8 cycles of adjuvant therapy, then, Durvalumab 1500mg, (IV, Q4W), up to 6 cycles
Study: NCT05031364

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Interventions for Anxiety in Children with Autism (BIACA)
Description: In the BIACA CBT program (e.g., Wood et al., 2020), clinicians work with families for 16 weekly sessions that include both the child and parent(s). In BIACA, anxiety, rigidity and inflexible routines, and irritability are all addressed using in vivo exposure therapy strategies during sessions as well as parent (and teacher) training to promote regulation across settings. ASD-related clinical needs that can impact mental health and emotion regulation such as friendship skills and social entry skills (e.g., joining games at school) are addressed with modeling, self-management, and parent- (or teacher-) implemented social coaching in daily settings. For youth with limited communication, therapy is adapted through the use of play-based representations of challenging situations and an emphasis on more action-oriented exposure therapy.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment-as-Usual Supplemented by Internet-Based Self-Instruction (MEYA)
Description: Participating clinicians are expected to have varied training in numerous psychological therapy procedures (e.g., insight-oriented procedures, cognitive interventions, family therapy, etc.), any or all of which they may choose to implement with a participating child. These practices will be characterized through the Therapy Procedures Checklist (Weersing et al., 2002). Additionally, participating clinicians will be provided with information about self-instruction resources on CBT for children with autism, namely, the Modular Evidence-Based Practices for Youth with Autism (MEYA) website developed by our research group. MEYA is freely accessible to clinicians worldwide at meya.ucla.edu. MEYA incorporates treatment elements of both BIACA (Wood et al., 2020) and SEBASTIEN (Wood et al., 2021), which was designed to address additional autism-related clinical needs (e.g., reciprocal conversation). Clinicians in this arm will provide up to 16 therapy sessions.
Study: NCT06195982

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ketone ester
Description: 500 mg/kg of ketone ester administered approximately 1 hour prior to the maximal exercise testing and 250 mg/kg administered approximately 30 minutes prior to submaximal exercise testing

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: ketone-free placebo administered approximately 1 hour prior to the maximal exercise testing and ketone-free placebo administered approximately 30 minutes prior to submaximal exercise testing
Study: NCT05662033

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: AZD6793 will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered orally
Study: NCT06525194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: An Interprofessional Education Program Based on the ARCS-V Motivation Model on the Theme of Chronic Disease Management and Patient Safety
Study: NCT04876196

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Selfapy for Bulimia Nervosa
Description: Web-based intervention for Bulimia Nervosa with six mandatory weekly sessions covering topics related to eating behaviors, emotion regulation, and stress management, followed by an optional set of up to six modular specialization areas based on individual therapy goals. During the intervention, participants can access an online chat providing crisis management, answering questions concerning the exercises, and technical support. The chat does not include the opportunity to discuss individual topics and concerns about treatment.
Study: NCT04877184

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial ultrasound stimulation and rehabilitation
Description: The participants in experimental group would received transcranial ultrasound stimulation and rehabilitation therapy.~* transcranial ultrasound stimulation: during 4 weeks~* rehabilitation: physiotherapy and occupational therapy (may combine with speech therapy and psychological therapy if needed)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation
Description: The participants in control group would received rehabilitation therapy.~- rehabilitation: physiotherapy and occupational therapy (may combine with speech therapy and psychological therapy if needed)
Study: NCT05684926

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telerehabilitation yoga
Description: Yoga consists of bodily postures or poses called asanas, breathing practices called pranayama, and meditation sections that provide focus. Children's yoga aims to teach pre-school (3-6 years) and school (7-12 years) children to breathe correctly, to practice yoga postures using their imaginations, to preserve their existing body flexibility and to teach correct posture. It consists of compositions such as postures, breathing exercises, imitations of living things in nature, memory games. They also relax with the pranayama breathing exercises done during the session. It aims to develop children's creativity through relaxation exercises, moving poses and stories told. Children's yoga also serves an artistic aspect with activities such as listening to music, singing, rhythm games, and drawing.
Study: NCT05232578

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Early salvage radiotherapy (eSRT)
Description: eSRT administered immediately after the confirmation of the biochemical relapse (PSA ≈ 0.2ng/ml).~66-70Gy will be delivered to the bed of prostate. Radiotherapy will be optionally accompanied by androgen deprivation therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Delayed Salvage radiotherapy (dSRT)
Description: dSRT administered if PSA levels increase to ≥ 0.4 ng/ml.~66-70Gy will be delivered to the bed of prostate. Radiotherapy will be optionally accompanied by androgen deprivation therapy.
Study: NCT05598437

Intervention type: DEVICE
Intervention: Dry eye device
Description: Dry eye analysis

Intervention type: DEVICE
Intervention: Dry eye device
Description: Dry eye analysis
Study: NCT04648410

Intervention type: OTHER
Intervention: questionnaire
Description: Members of European Society of Intensive Care will obtain an electronic survey considering their routine clinical practice regarding the administration of systemic corticosteroids among patients with COVID-19 ARDS
Study: NCT06355739

Intervention type: DEVICE
Group type: OTHER
Intervention: CAR T cell injection
Description: intravenous injection
Study: NCT06358573

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INT230-6
Description: INT230-6 is a formulation consisting of an proprietary amphiphilic cell penetration enhancer molecule, 8-((2-hydroxybenzoyl)amino)octanoate, also referred to as SHAO, combined with cisplatin and vinblastine sulfate.~The IMP is without marketing authorization in Switzerland and anywhere in the world.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: neoadjuvant immuno-chemotherapy
Description: Standard of care

Intervention type: OTHER
Group type: OTHER
Intervention: neoadjuvant immuno-chemotherapy
Description: Standard of care
Study: NCT06202833

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acupuncture with regulating immunity as the core of treatment
Description: The patient was supine, the acupuncture points were disinfected with 75% ethanol, and the acupuncture points on the head and neck were first acupuncture, and then the acupuncture points on the abdomen and limbs. baihui: When the 1.5 inch millimeter needle is needled, the tip of the needle and the acupoint are at a 15-30 ° Angle, and the needle is about 1 inch flat along the subcutaneous area. The twisting speed is about 200 times per minute, and the stitches are once every 15 minutes, and each stitch is about 30 seconds. zhongwan, tianshu: 1.5 inch needle straight puncture 1 inch, small amplitude lifting and twisting. guanyuan, qihai: 1.5 inch millimeter needle downward oblique puncture 1 inch, small amplitude lifting and twisting. The above acupoints were measured by obtaining qi, and the needles were retained for 30min, once a day.5 days a week for 4 weeks.Twenty days in total.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Needles that are not on acupoints
Description: In this group, acupuncture treatment was performed at 1cm side of the selected points of the Tongyuan acupoint acupuncture group.The piercing Angle is the same as the test group, only piercing, not twisting.Once a day, 5 days a week for 4 weeks.Twenty days in total.
Study: NCT06333587

Intervention type: PROCEDURE
Intervention: image-guided thermal ablation
Description: image-guided thermal ablation in patients with diagnosis of micropapillary thyroid carcinoma
Study: NCT04762368

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active anodal tDCS
Description: a weak electric current is applied to the head through electrodes to affect the cortical excitability of the targeted cells in the brain.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham anodal tDCS
Description: The tDCS machine will be used as in active stimulation, except the electrical current will not be applied.