TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05289310

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normobaric hypoxia (NH)
Description: Low oxygen exposure to mimic \~8500 feet elevation (experimental).

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Normobaric normoxia (NN)
Description: Normal oxygen exposure to mimic sea level conditions (sham comparator).
Study: NCT06392165

Intervention type: OTHER
Group type: OTHER
Intervention: self-adhesive device
Description: Test device which is self-adhesive
Study: NCT06285396

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ephedrine
Description: Ephedrine in solution, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ephedrine
Description: Ephedrine in solution, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phenylephrine
Description: Phenylephrine, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phenylephrine
Description: Phenylephrine, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: Norepinephrine, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: Norepinephrine, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxytocin
Description: Oxytocin, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxytocin
Description: Oxytocin, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxytocin
Description: Oxytocin, at applicable concentrations based on literature.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxytocin
Description: Oxytocin, at applicable concentrations based on literature.
Study: NCT04104256

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nudge #1: Alert highlighting the safety/potential harms to patients of undergoing pre-op tests
Description: Nudge 1:~* UCLA Ophthalmologists and Anesthesiologists ADVISE AGAINST routine pre-op testing.~* UCLA Pre-op Eval and Planning Center (PEPC) will order any needed labs on the day of surgery.~* Routine pre-op tests are inappropriate.~* Routine pre-op tests do NOT increase patient safety and go AGAINST local and national guidelines Hard stop before allowing the ordering of a pre-op test where physicians must provide accountable justification: EXPLAIN WHY GOING AGAINST GUIDELINES

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nudge #2: Alert highlighting the financial harms to the patient experiencing pre-op tests
Description: Nudge #2:~* UCLA Ophthalmologists and Anesthesiologists ADVISE AGAINST routine pre-op testing.~* UCLA Pre-op Eval and Planning Center (PEPC) will order any needed labs on the day of surgery.~* Routine pre-op tests are inappropriate.~* Routine pre-operative tests can increase the patient's out-of-pocket costs without improving the safety or medical outcomes of cataract surgery and go AGAINST local and national guidelines~* Nudge includes hard stop before allowing the ordering of a pre-op test where physicians must provide accountable justification: EXPLAIN WHY GOING AGAINST GUIDELINES

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nudge #3: Alert highlighting potential psychological harms to the patient of experiencing pre-op tests
Description: Nudge 3:~* UCLA Ophthalmologists and Anesthesiologists ADVISE AGAINST routine pre-op testing.~* UCLA Pre-op Eval and Planning Center (PEPC) will order any needed labs on the day of surgery.~* Routine pre-op tests are inappropriate.~* Routine pre-operative tests can cause aggravation and psychological stress for the patient without improving the safety or medical outcomes of cataract surgery and go AGAINST local and national guidelines~* Hard stop before allowing the ordering of a pre-op test where physicians must provide accountable justification: EXPLAIN WHY GOING AGAINST GUIDELINES

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Patients will receive usual care from their physicians.
Study: NCT04917107

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Qigong
Description: The Five Element Qigong Healing Movements practice includes five gentle horizontal and vertical arm and leg movements performed with guided breathing.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Qigong
Description: The Five Element Qigong Healing Movements practice includes five gentle horizontal and vertical arm and leg movements performed with guided breathing.
Study: NCT06390722

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Upadacitinib
Description: Oral Tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for Upadacitinib
Description: Oral Tablet
Study: NCT05096403

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pegcetacoplan
Description: Pegcetacoplan taken twice weekly as subcutaneous injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pegcetacoplan
Description: Pegcetacoplan taken twice weekly as subcutaneous injection
Study: NCT06184061

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Herbal Supplement
Description: Herbal supplement will be the mixture of strawberry, black mulberry, blueberry, raspberry, ginseng, ashwagandha, honey, water
Study: NCT04936945

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Temporomandibular joint arthroscopy plus intra-articular injection
Description: patients with TMJ degenerative joint diseases Wilkes stages IV, V not responding to conservative treatment will undergo operative diagnostic arthroscopic treatment then at the end of the procedure intra-articular injection of platelet rich plasma or hyaluronic acid will be done.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Temporomandibular joint arthroscopy plus intra-articular injection
Description: patients with TMJ degenerative joint diseases Wilkes stages IV, V not responding to conservative treatment will undergo operative diagnostic arthroscopic treatment then at the end of the procedure intra-articular injection of platelet rich plasma or hyaluronic acid will be done.
Study: NCT05291520

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VH3810109
Description: VH3810109 was administered.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VH3810109
Description: VH3810109 was administered.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VH3810109
Description: VH3810109 was administered.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: rHuPH20
Description: rHuPH20 was administered.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: rHuPH20
Description: rHuPH20 was administered.
Study: NCT05650606

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Gait Training
Description: Physical therapy intervention for improving gait in patients post Cerebral Vascular Accident.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Therapy
Description: Standard inpatient rehabilitation physical therapy treatments for Cerebral Vascular Accident.
Study: NCT05924243

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RO7486967
Description: For up to approximately 28 days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: For up to approximately 28 days
Study: NCT05861466

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: intra-vitreal injection of Ranibizumab
Description: The intravitreal injection will be performed with ranibizumab (0.5 mg/0.05 mL through a 27-gauge needle that will be inserted into the sclera 3.5 mm from the corneal limbus in pseudophakic patients, and 4 mm in phakic patients.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: intra-vitreal injection of Ranibizumab
Description: The intravitreal injection will be performed with ranibizumab (0.5 mg/0.05 mL through a 27-gauge needle that will be inserted into the sclera 3.5 mm from the corneal limbus in pseudophakic patients, and 4 mm in phakic patients.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: anterior chamber paracentesis
Description: A 27-gauge needle on a 1-mL syringe will be inserted into the anterior chamber of the eye, and approximately 0.05 mL of aqueous humor will be withdrawn.
Study: NCT06520501

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Herbal Medicine Sambiloto
Description: Jamu Sambiloto is herbal medicine obtained through products that already have a distribution permit and have a distribution permit registration number, with a consumption dose of 1 capul / day or 350 grams for 7 consecutive days.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brisk Walking
Description: Moderate activity that uses brisk walking techniques for 30 minutes at an average speed of up to 5 km/h or 100 steps per minute.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Brisk Walking and Herbal Medicine Sambiloto
Description: Moderate activity that uses brisk walking techniques for 30 minutes at an average speed of up to 5 km/h or 100 steps per minute. Jamu Sambiloto is herbal medicine obtained through products that already have a distribution permit and have a distribution permit registration number, with a consumption dose of 1 capul / day or 350 grams for 7 consecutive days
Study: NCT05719103

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: With and Without Awake Prone Positioning
Description: 1. HFNC flow at 60 L/min or maximum tolerable flow at supine position~2. HFNC flow at 60 L/min or maximum tolerable flow at prone position~3. CPAP with full face mask at 10 cmH2O at supine position~4. CPAP with full face mask at 10 cmH2O at prone position~5. MC at supine position~6. MC at prone position

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: With and Without Awake Prone Positioning
Description: 1. HFNC flow at 60 L/min or maximum tolerable flow at supine position~2. HFNC flow at 60 L/min or maximum tolerable flow at prone position~3. CPAP with full face mask at 10 cmH2O at supine position~4. CPAP with full face mask at 10 cmH2O at prone position~5. MC at supine position~6. MC at prone position

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: With and Without Awake Prone Positioning
Description: 1. HFNC flow at 60 L/min or maximum tolerable flow at supine position~2. HFNC flow at 60 L/min or maximum tolerable flow at prone position~3. CPAP with full face mask at 10 cmH2O at supine position~4. CPAP with full face mask at 10 cmH2O at prone position~5. MC at supine position~6. MC at prone position

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: With and Without Awake Prone Positioning
Description: 1. HFNC flow at 60 L/min or maximum tolerable flow at supine position~2. HFNC flow at 60 L/min or maximum tolerable flow at prone position~3. CPAP with full face mask at 10 cmH2O at supine position~4. CPAP with full face mask at 10 cmH2O at prone position~5. MC at supine position~6. MC at prone position

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: With and Without Awake Prone Positioning
Description: 1. HFNC flow at 60 L/min or maximum tolerable flow at supine position~2. HFNC flow at 60 L/min or maximum tolerable flow at prone position~3. CPAP with full face mask at 10 cmH2O at supine position~4. CPAP with full face mask at 10 cmH2O at prone position~5. MC at supine position~6. MC at prone position

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: With and Without Awake Prone Positioning
Description: 1. HFNC flow at 60 L/min or maximum tolerable flow at supine position~2. HFNC flow at 60 L/min or maximum tolerable flow at prone position~3. CPAP with full face mask at 10 cmH2O at supine position~4. CPAP with full face mask at 10 cmH2O at prone position~5. MC at supine position~6. MC at prone position
Study: NCT06358612

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stress Balls
Description: Patients in the experimental arm will receive a foam stress ball to squeeze during their biopsy procedure.
Study: NCT06506253

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swedish Massage Therapy
Description: Touch therapy

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Light Touch Therapy
Description: Touch therapy
Study: NCT04337372

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Book reading
Description: Parent and their infant will read a short book in the laboratory. Books will include three labeling conditions expected to elicit different levels of attention.
Study: NCT05416203

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Enhanced Anxiety Sensitivity Treatment
Description: BEAST is a CBT-based intervention that includes psychoeducation, identifying and challenging maladaptive thoughts, and interoceptive exposure. The intervention is delivered through a single virtual face-to-face session supplemented with a mobile app for two weeks after the face to face session.
Study: NCT06463795

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS
Description: active anodal tDCS

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham tDCS
Description: sham anodal tDCS
Study: NCT05338528

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BE-FIT exercise program
Description: BE-FIT is an evidence-based exercise program that focuses on early mobilization and recovery by minimizing bed rest, promoting functional tasks, and encouraging self-management. The intervention ist based on the Mobilization of Vulnerable Elders (MOVE) program and consists of a bedside exercise plan, done independently by the patient without the need for additional rehabilitation or healthcare staff.
Study: NCT05922137

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Usual Diet advice
Description: The usual diet advice include recommendations in guidelines, such as reducing salt and limiting alcohol consumption

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Oriental Intervention for Enhanced Neurocognitive Health (ORIENT) diet
Description: The ORIENT diet has the same basic components of the Dietary Approaches to Stop Hypertension (DASH), Mediterranean and MIND diets, but uniquely adjusting some of components according to the evidence derived from Asian prospective cohorts and the Chinese eating habits.
Study: NCT05291260

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cast immobilization
Description: A cast to immobilize the MCP, in 10-30 degrees (slight) flexion (neutral position), and the CMC joint, in 30-40 degrees palmar abduction, is applied (IP joint is free).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical treatment
Description: In general, two surgical techniques are described in literature and used in daily clinical practice:~* If the UCL is ruptured in the middle of the ligament, sutures are used to reattach the ligament remnants together.~* When no viable UCL ligaments are present, the UCL is reattached directly to the bone using suture anchors.
Study: NCT05572359

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cryo-and compression brace
Description: patients in the intervention groups are instructed to use the cryo- and compression brace during the six postoperative weeks five times a day, for a maximum of 20 minutes. The amount of compression is dependent on a patients' own preference.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cryo-and compression brace
Description: patients in the intervention groups are instructed to use the cryo- and compression brace during the six postoperative weeks five times a day, for a maximum of 20 minutes. The amount of compression is dependent on a patients' own preference.
Study: NCT05690308

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual perturbation treadmill training
Description: 12 sessions of (max 30 minutes) walking at comfortable speed on an instrumented treadmill in a virtual reality environment (Gait Real-time Analysis Interactive Lab system, MOTEK) with projected visual perturbations.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Regular treadmill training
Description: 12 sessions of (max 30 minutes) walking at comfortable speed on an instrumented treadmill
Study: NCT05786625

Intervention type: DEVICE
Intervention: Ablation
Description: Bronchoscopy and microwave ablation of lung nodule
Study: NCT06074835

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gamete preparation, ICSI, embryo culture and vitrification robot assistant
Description: Patients undergoing an assisted conception treatment with medical indication to perform ICSI may be recruited in this study. The study will follow a sibling-oocyte and/or sibling embryo study design where oocytes and/or embryos obtained from a specific patient or couple will be randomly distributed across two groups (test and control) and undergo one or more elements of an automated assisted conception laboratory workflow (for the test group) or a standard assisted conception laboratory workflow (for the control group). Before distributing the samples, an embryologist will slightly blur the vision of the samples so that their morphology can no longer be clearly assessed. Robotic automation may include any of the following steps: robotic sperm preparation, robotic oocyte selection and denudation, robotic sperm injection, automated embryo culture, and automated cryopreservation. The resulting embryos may be employed for embryo transfer.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Manual ICSI Workflow
Description: Routine Manual Icsi Workflow
Study: NCT06150638

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biofeedback
Description: Three sessions of biofeedback intervention will be performed during the first 3 weeks of the intervention period. Patients will be taught to control abdominal and thoracic muscular activity by providing instructions using an original video support. Patients will be instructed to perform the same exercises before and after breakfast, lunch and dinner during the 4-week intervention period.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Three sessions of placebo intervention will be performed during the first 3 weeks of the intervention period. Sham measurements of abdominal and thoracic motion will be performed, and a pill of placebo containing 0.21 g glucose will be administered; patients will be instructed to take a pill of placebo before breakfast, lunch and dinner during the 4-week intervention period.
Study: NCT05697770

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium bicarbonate
Description: Sodium bicarbonate 8.4% will be continuously infused for a maximum of 5 hours. The infusion will start at 100 mL/hr and be kept at this rate until both pH and BE targets are achieved, following which, the infusion rate will be decreased to 25 mL/hr and kept constant at this rate until 5 hours has elapsed since the start of the infusion. At this point, the infusion will be stopped, independently, of the results of arterial blood gas analysis.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5% Dextrose
Description: 5% dextrose will be continuously infused for a maximum of 5 hours. The infusion will start at 100 mL/hr and be kept at this rate until both pH and BE targets are achieved, following which, the infusion rate will be decreased to 25 mL/hr and kept constant at this rate until 5 hours has elapsed since the start of the infusion. At this point, the infusion will be stopped, independently, of the results of arterial blood gas analysis.
Study: NCT05579782

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NIRAF Detection Technology
Description: Near Infrared Autofluorescence (NIRAF) detection technology or 'PTeye' consists of a disposable fiber-optic probe that emits non-ionizing radiation from a NIR 785 nm laser source, and also transmits the resulting tissue NIRAF to a photo detector. The 785 nm laser source emits a maximum power of 20 mW. The device is FDA cleared for clinical use in general surgeries and dermatological use (Class 2 device).~After surgeon identifies a potential parathyroid gland in the surgical field, the surgeon places the fiber-optic probe of PTeye on suspect tissue and presses the device foot-pedal to activate tissue NIRAF measurement. Auditory beep at high frequency with a Detection Ratio \> 1.2 is interpreted by device as the suspect tissue being positive for parathyroid.~Other Name: PTeye Device
Study: NCT06254638

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multicomponent school-based intervention.
Description: Physically active learning: this type of intervention is carried out once a week for 1 hour outside the classroom. The teachers of the corresponding subject (with the support of the research team) are in charge of the physically active classes.~Active break: the intervention consists of 2 active pauses per day. The development of each pause is carried out through a specific digital platform in which students follow the instructions of an avatar, who is in charge of guiding the realization of the active break. Each active break takes a total of 4 minutes, in which two sets of 20 seconds of work and 10 seconds of rest of four different exercises are performed.~Active break: The intervention consists of a daily active break, every school day of the week. The design and supervision of each active break will be carried out by the support technician and the teaching staff based on the students' tastes.
Study: NCT05716958

Intervention type: RADIATION
Intervention: Digital Breast Tomosynthesis
Description: Digital Breast Tomosynthesis (DBT) is a type of 3D mammography that creates detailed images of the breast tissue. It uses X-rays to take multiple images at different angles and combines them to create a clear, layered view of the breast tissue. DBT is used for breast cancer screening and diagnosis and provides a more accurate view of the breast tissue compared to traditional 2D mammography.

Intervention type: RADIATION
Intervention: Digital Breast Tomosynthesis
Description: Digital Breast Tomosynthesis (DBT) is a type of 3D mammography that creates detailed images of the breast tissue. It uses X-rays to take multiple images at different angles and combines them to create a clear, layered view of the breast tissue. DBT is used for breast cancer screening and diagnosis and provides a more accurate view of the breast tissue compared to traditional 2D mammography.
Study: NCT06222853

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-CD19-CAR-T cells
Description: Three dose groups (0.3×10\^5/kg, 1×10\^5/kg, 3×10\^5/kg) were set up, starting from the low dose group climbing to explore the safe and effective dose.