TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05599555

Intervention type: BIOLOGICAL
Intervention: mRNA BNT162b2 vaccine
Description: mRNA vaccine Comirnaty (BNT162b2 mRNA, BioNTech/Fosun-Pharma, Mainz, Germany/Shanghai, China)

Intervention type: BIOLOGICAL
Intervention: CoronaVac vaccine
Description: Inactivated CoronaVac vaccine (Sinovac Life Sciences, Beijing, China)
Study: NCT05427084

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Canagliflozin
Description: Canagliflozin tablet 300mg PO daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet
Study: NCT04446728

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Training Webinar
Description: The training webinar is a three hour training. The purpose of the study is to implement the Psychosocial Assessment Tool (PAT) in their center.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Training Webinar
Description: The training webinar is a three hour training. The purpose of the study is to implement the Psychosocial Assessment Tool (PAT) in their center.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Training Webinar Plus Implementation Enhanced Resources (TIER)
Description: In addition the Training Webinar, sites randomized to Strategy II will identify a Champion and will participate in monthly consultation calls in support of implementation of the PAT
Study: NCT06675825

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BougieCap
Description: The BougieCap is attached to the tip of the endoscope, offers direct visual and tactile control and the endoscope acts as a carrier of the radial and longitudinal force vectors for the dilation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Savary-Bougie (A) or balloon dilation (B)
Description: A: In the Savary- Bougie treatment, dilators of different sizes are advanced to dilate the stenosis. The same procedure is then repeated with the next larger dilator, with the position of the dilator being checked radiologically each time.~B: In the case of balloon dilation, a balloon is inserted and inflated at the level of the stenosis. Depending on the age of the child and possibly also the etiology of the stenosis, different balloons sizes are applied, which are then maintained inflated for about one until three minutes and the respective pressure. This procedure could take place under endoscopic or radiological control.
Study: NCT05038800

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MK-0482
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MK-0482
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MK-0482
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MK-0482
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MK-0482
Description: IV infusion
Study: NCT06697028

Intervention type: OTHER
Intervention: Usability and Comparison
Description: PACER will be used to assess cardiorespiratory fitness in individuals with rheumatic diseases. The results will be compared with those of healthy individuals, and the relationship between body composition and VO2 max will be examined.

Intervention type: OTHER
Intervention: Usability and Comparison
Description: PACER will be used to assess cardiorespiratory fitness in individuals with rheumatic diseases. The results will be compared with those of healthy individuals, and the relationship between body composition and VO2 max will be examined.

Intervention type: OTHER
Intervention: Usability and Comparison
Description: PACER will be used to assess cardiorespiratory fitness in individuals with rheumatic diseases. The results will be compared with those of healthy individuals, and the relationship between body composition and VO2 max will be examined.
Study: NCT06723171

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IRX4204
Description: Active Treatment
Study: NCT04891666

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus plantarum DSM 33464
Description: 1 sachet SmartGuard® per day for 12 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 sachet of placebo per day for 12 weeks
Study: NCT05328427

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stopping
Description: Discontinuation of nucleoside analogue
Study: NCT06492447

Intervention type: DRUG
Intervention: Against HER 2-ADC Drug
Description: Breast cancer subjects receiving anti-HER2-ADC drugs were treated with a 3-week treatment cycle lasting 6 cycles. Serum of patients before and after treatment was collected, and the changes of serum HER2 level before chemotherapy and after 2, 4 and 6 cycles of chemotherapy were dynamically monitored, and the relationship between HER2 level and the therapeutic effect of different targeted drugs was analyzed.
Study: NCT05083663

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyaluronidase
Description: using hyaluronidase as an additive to bupivacaine
Study: NCT05271565

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oligomeric enteral feeding
Description: Oligomeric enteral formula

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Polymeric enteral feeding
Description: Polymeric enteral feeding will be administered to the PICU patients
Study: NCT05084976

Intervention type: BEHAVIORAL
Intervention: COVID 19 vaccine counseling
Description: After surveys are completed, pulmonary provider (nurse practitioner or physician) will provide counseling via phone or in person about the COVID 19 vaccine. Safety, efficacy and side effects will be reviewed.

Intervention type: BEHAVIORAL
Intervention: COVID 19 vaccine counseling
Description: After surveys are completed, pulmonary provider (nurse practitioner or physician) will provide counseling via phone or in person about the COVID 19 vaccine. Safety, efficacy and side effects will be reviewed.
Study: NCT05529537

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: manual lymphatic drainage
Description: In addition to conventional treatment for 4 weeks, manual lymph drainage will be applied to the patients.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: excersize
Description: upper extremity normal joint range of motion exercise, strengthening exercise, tendon gliding exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: excersize
Description: upper extremity normal joint range of motion exercise, strengthening exercise, tendon gliding exercises
Study: NCT06122389

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2554; Chidamide analog tablets
Description: SHR2554 + Chidamide analog tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2554 analog tablets; Chidamide
Description: SHR2554 analog tablets + Chidamide
Study: NCT06723171

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06715878

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Zero Ischemia Robot-Assisted Laparoscopic Microwave Ablation Assisted suture-less Enucleation
Description: Under the visualization of ultrasound contrast imaging through the operative channel, a microwave ablation probe was inserted into the tumor (at the interface between the tumor and kidney, close to the tumor base). The microwave ablation device was used, with a power setting of 70 W for initiating microwave ablation. Depending on the tumor volume and depth, 1-3 ablation cycles were performed, with each cycle lasting 1-3 minutes. After reaching the pseudocapsule of the tumor, a combination of blunt dissection, sharp cutting, and blunt dissection was employed to separate the tumor from the renal parenchyma . The renal artery was not occluded during the procedure.If intraoperative injury to the collecting system is suspected, the collecting system should be sutured normally, while simultaneously suturing the outer layer of renal parenchyma to prevent urine leakage.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: robotic-assisted laparoscopic partial nephrectomy
Description: robotic-assisted laparoscopic partial nephrectomy
Study: NCT05036941

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acteev™ Masks
Description: Participants will wear the mask on every shift for 8 consecutive weeks. Participants in Arm 1 will be supplied adequate number of Acteev™ N95 masks YQD8008 during 8-hour shift and Acteev™ fabric masks for community use.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Comparison Masks
Description: Participants will wear the mask on every shift for 8 consecutive weeks. Participants in Arm 2 will be supplied with adequate number of standard N95 masks during 8-hour shift and fabric mask for community use.
Study: NCT04776408

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lung recruitment combined inhaled Nitric oxide
Description: Ventilator combined inhaled Nitric oxide and Electrical Impedance Tomography monitor the V/Q mismatch

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Lung recruitment
Description: Ventilator and Electrical Impedance Tomography monitor the V/Q mismatch
Study: NCT06717971

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exergame-based multicomponent training program.
Description: The training program for the intervention group utilized the Nintendo Switch game WarioWare: Move It,. Participants engaged with the game through Joy-Con controllers, completing rapid micro-games designed to meet specific movement-oriented objectives. Each game session lasted approximately five seconds, requiring participants to quickly adapt to various physical actions and postures, such as waving, jumping, swinging arms, rotating, and mimicking object movements. The game's dynamic structure provides an engaging experience that promotes physical coordination, reaction speed, upper and lower limb strength, and hand-eye coordination through diverse movement patterns. Switching between tasks compels players to adjust to varying motion demands swiftly, enhancing physical agility while strengthening attention-shifting and quick decision-making skills.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard care
Description: The standard care program for the control group is grounded in routine practices of long-term care facilities, aiming to sustain and enhance the physical and mental well-being of elderly residents through structured group activities. These activities encompass tailored fitness exercises, horticultural therapy, and sedentary group engagements for older adults. The fitness exercises are adapted to meet the varying physical conditions of participants, ensuring a safe and comfortable environment that promotes moderate physical activity. Horticultural therapy involves hands-on planting and tending to plants, stimulating the senses, and fostering emotional regulation, contributing to improved psychological health. Sedentary activities, such as tabletop games, emphasize social interaction and cognitive maintenance by promoting a relaxed social environment that helps participants remain cognitively engaged.
Study: NCT06729879

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yoga eye exercises group:
Description: Yoga eye exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial release-postural correction exercises group
Description: Myofascial release-postural correction exercises

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Yoga eye exercises, myofascial release-postural correction exercises group
Description: Yoga eye exercises, myofascial release-postural correction exercises group

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: control group
Description: no intervention
Study: NCT06727643

Intervention type: OTHER
Group type: OTHER
Intervention: trunk muscle strength
Description: force that represents the endurance of the body.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: trunk muscle strength
Description: force that represents the endurance of the body.

Intervention type: OTHER
Group type: OTHER
Intervention: Core Strength
Description: back and abdominal muscle endurance

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Core Strength
Description: back and abdominal muscle endurance

Intervention type: OTHER
Group type: OTHER
Intervention: Balance
Description: steady state

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Balance
Description: steady state
Study: NCT06729593

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Remdesivir
Description: Administered by IV infusion, daily for 10 days. Initial loading dose is 200 mg with all subsequent doses 100 mg.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Remdesivir Placebo
Description: Commercially available 0.9% sodium chloride solution. Administered by IV infusion daily for 10 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Corticosteroid
Description: In line with NIH treatment guidelines, corticosteroids such as dexamethasone, prednisone, methylprednisolone or hydrocortisone may be administered as SOC.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Corticosteroid
Description: In line with NIH treatment guidelines, corticosteroids such as dexamethasone, prednisone, methylprednisolone or hydrocortisone may be administered as SOC.
Study: NCT06728605

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Enhanced External Counterpulsation (EECP)
Description: Patients randomly assigned to EECP received 3 1/2-h sessions of EECP for 3 days before surgery. Three pneumatic cuffs will be placed around the lower limbs and buttocks and will be inflated sequentially upward at the onset of diastole, and released rapidly and simultaneously before the onset of systole. The protocol-specified applied pressure will be 300 mm Hg and was reached within 5 min of the initiation of treatment. Pulse oximetry will be monitored continuously during the treatment session, and the subject's clinical status will be re-evaluated if the oxygen saturation drops by 4%.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Comparator
Description: Patients randomly assigned to sham group received 3 1/2-h sessions of sham treatment for 3 days before surgery. Three pneumatic cuffs will be placed around the lower limbs and buttocks and will be inflated sequentially upward at the onset of diastole, and released rapidly and simultaneously before the onset of systole. The protocol-specified applied pressure will be 70 mm Hg and was reached within 5 min of the initiation of treatment. Pulse oximetry will be monitored continuously during the treatment session, and the subject's clinical status will be re-evaluated if the oxygen saturation drops by 4%.
Study: NCT06728540

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Investigation of Physical Activity Levels, Respiratory and Pelvic Floor Muscle Function
Description: The sociodemographic and clinical characteristics of the children participating in the study will be evaluated with an evaluation form, respiratory muscle strength with an RP Check brand electronic pressure measurement device, and body composition with a Tanita MC-580 brand bioelectrical impedance analyzer. Pelvic floor muscle functions of children with LUTD will be evaluated with a 632 Myomed biofeedback device. The survey questions and the evaluation form will be filled out by the parents.

Intervention type: OTHER
Group type: OTHER
Intervention: Investigation of Physical Activity Levels, Respiratory and Pelvic Floor Muscle Function
Description: The sociodemographic and clinical characteristics of the children participating in the study will be evaluated with an evaluation form, respiratory muscle strength with an RP Check brand electronic pressure measurement device, and body composition with a Tanita MC-580 brand bioelectrical impedance analyzer. Pelvic floor muscle functions of children with LUTD will be evaluated with a 632 Myomed biofeedback device. The survey questions and the evaluation form will be filled out by the parents.
Study: NCT06728592

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Portable Magnetic Resonance Imaging
Description: 0.23T Low-field Magnetic Resonance Imaging
Study: NCT06728046

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ESPB
Description: Participants will receive ultrasound-guided ESPB preoperatively, using 40 ml of 0.3% ropivacaine.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PCA
Description: Participants will receive postoperative PCA with a formulation of 200 µg sufentanil diluted to 100 ml. The PCA settings will include a background dose of 3 ml/hour, a lockout time of 15 minutes, and a bolus dose of 2 ml.
Study: NCT06727942

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: V-TARGET intervention
Description: V-TARGET intervention will be delivered through a 360 degree self-paced treadmill in a university clinical laboratory for 5-weeks (2 days/week, 30 minutes/session) with total 10 sessions. The treadmill is the first-of-kind motion platform that an individual can walk and run at self-paced speed in 360 degree (i.e., forwards, sideways and backwards) without risk of falling or colliding with other people. During the V-TARGET intervention, participants will self-pace their locomotor action (walking/running) while they wear the HTC vivo headset and experience daily exercises/games augmented by the VR Therapy System. Therapy System is a library of VR exercises/games targeted on neurological rehabilitation, balance improvement training as well as cognitive therapy suited for variety of conditions, and includes various daily living simulation activities such as Retail Shopping, Gait Training, Cafeteria Experience, and Nature Walk.
Study: NCT06728306

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Immersive Virtual Reality-Based Relaxation
Description: Participants experienced a 20-minute immersive relaxation session using the virtual reality headset and the Nature Treks application, while seated comfortably. Participants were instructed to select the natural environment they found most relaxing from options such as Blue Ocean, Orange Sunset, Violet Down, White Winter, and Green Meadows, and spent 20 minutes immersed in their chosen virtual environment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Non-immersive VR-Based Exergaming
Description: Participants engaged in a 20-minute calisthenic exercise session guided by the Kinect Adventures game on the Xbox Kinect 360 system. The exercise session consisted of playing two rounds each of the game segments 20,000 Leaks, Reflex Ridge, and River Rush, each lasting approximately 3 minutes

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Jacobson's Relaxation
Description: Participants underwent 20 minutes of progressive relaxation training as developed by Dr. Jacobson. The training involves a series of deep diaphragmatic breaths followed by the systematic tensing and relaxing of 16 major muscle groups throughout the body. Participants were guided through the exercise by an approximately 20-minute audio recording prepared by a psychologist and available online
Study: NCT06727799

Intervention type: OTHER
Intervention: Docking Assessment / Observation
Description: One eye of each subject will have corneal marks placed and will be docked at the study visit.
Study: NCT06007222

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin group
Description: Aspirin 100mg will be started within 24 hours after randomization, and continued aspirin 100mg/day the end of the study period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Non-antithrombotic group
Description: No antithrombotic agents will be administered after randomization until the end of the study period.
Study: NCT05243563

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MonaLisa Touch
Description: 3 laser treatments at 6 week intervals for 6 months by a single trained operator

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical steroid
Description: self-applied topical steroid therapy using clobetasol propionate 0.05%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical steroid
Description: self-applied topical steroid therapy using clobetasol propionate 0.05%
Study: NCT05850598

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham rTMS
Description: The coil was held while disconnected from the stimulator, and rTMS noise was presented with computer loudspeakers with recorded sound from a real stimulation (20 minutes for each side of the lateral cerebellum everyday for 2 weeks).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active rTMS
Description: Low-frequency (1 Hz) rTMS at with a stimulation intensity of 95% of the motor threshold will be delivered over the bilateral cerebellum for patients with Parkinson's disease (20 minutes for each side of the lateral cerebellum everyday for 2 weeks).
Study: NCT04811014

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buprenorphine, Naloxone Drug Combination
Description: 8mg of buprenorphine/2mg of naloxone to initiate MOUD treatment and bridge, if necessary, until referral to MOUD clinic can be made for ongoing treatment

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Individual Counseling
Description: One-on-one counseling with a licensed chemical dependency counselor

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Recovery Support Services
Description: 24/7 support from our team of certified peer recovery support specialists to assist with emotional support and case management

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support Group
Description: Referrals to youth-focused support groups and eventual creation of in-house youth-focused support groups

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Referral to Medication Management
Description: Study staff will refer patients to long-term MOUD providers in the community

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Assertive Outreach
Description: The investigators will conduct weekly outreach to youths who experienced an opioid overdose and attempt to initiate treatment. Outreach is completed by a paramedic and peer coach.
Study: NCT05343663

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Self-Management Program Conducted with Tele-Nursing will increase Treatment/Disease Adaptation, Self-Efficacy, Self-Care Management in Hypertension Patients.