TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04880044

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: EsoCheck/EsoGuard (EC/EG)
Description: EC is a swallowed capsule on a tethered catheter that obtains a touch sample of the distal esophagus. The obtained sample is placed in a buffer and sent to a diagnostics lab for testing of methylated markers from extracted DNA. EG is a methylated DNA test . A positive EG is associated with Barrett's esophagus at all its stages.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Esophago-gastro-duodenoscopy (EGD)
Description: SOC diagnostic endoscopic procedure that visualizes the upper part of the gastrointestinal tract down to the duodenum. Tissue samples collected.
Study: NCT05964023

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: pBFS rTMS
Description: Participants will receive 3 sessions per day of 1800 pulses per session, lasting for 21 days. Individualized targets will be generated using the pBFS method.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 5-cm rTMS
Description: Participants will receive 3 sessions per day of 1800 pulses per session, lasting for 21 days. Individualized targets will be localized by 5-cm rule.
Study: NCT05604755

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HQP1351( Olverembatinib dimesylate)
Description: HQP1351 was initiated at a dose of 40mg every two days
Study: NCT04487249

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vision Therapy
Description: 20 consecutive weeks of office-based vision therapy with home therapy that aim to improve the participant's vergence skills, accommodative skills, and sensory fusion.
Study: NCT04828096

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Orthodontic retention
Description: The stability of the mandibular anterior teeth after two resp. 5 years of retention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Orthodontic retention
Description: The stability of the mandibular anterior teeth after two resp. 5 years of retention

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Orthodontic retention
Description: The stability of the mandibular anterior teeth after two resp. 5 years of retention
Study: NCT05608070

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin 30 IU in 500 ml IV at a rate of 5 IU/h (83.33 ml/h). The infusion will be started intra-operative once the uterus is removed and will continue to run until completion of the medication or discharge from PACU criteria are met, whichever occurs first.
Study: NCT05602181

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ALL Phonics Instruction
Description: The Accessible Literacy Learning (ALL) App is available in the app store and created by TobiiDynavox (an AAC device company). The ALL app is evidence informed and includes pre-made lessons in early phonics/phonological skills including: letter-sounds, sound blending, decoding, phoneme segmentation, sight words, and encoding. The materials made in the app are adapted and created for children with minimal or no speech.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ALL Sight Word Instruction
Description: The Accessible Literacy Learning (ALL) App is available in the app store and created by TobiiDynavox (an AAC device company). The ALL app is evidence informed and includes pre-made lessons in early phonics/phonological skills including: letter-sounds, sound blending, decoding, phoneme segmentation, sight words, and encoding. The materials made in the app are adapted and created for children with minimal or no speech. This group will only use the sight word lessons, as well as the library for sight word books. No phonics instruction will be provided through the app.
Study: NCT04682015

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: WeChat platform group
Description: Participants in the intervention group will receive educational messages related to hypertension, such as impact of hypertension on cardiovascular system, lifestyle adjustment and side effects of antihypertensive drugs. Participants will be reminded to take their blood pressure regularly and enter the blood pressure readings into the WeChat platform. If participants enter extremely high or low readings, they will be asked to seek medical help from doctors. Participants can also consult doctors online via WeChat platform by text and voice messages, or voice calls.
Study: NCT05599607

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic mixture
Description: Mixture of strains of lactobacillus and bifidobacteria

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Maltodextrin
Study: NCT05924698

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrostimulation
Description: Consisting of the use of NMES (biphasic symmetrical pulse, bipolar mode, 50Hz frequency, pulse duration 300 μs at 1:1 ratio) (S82®; Enraf-Nonius BV, Rotterdam, The Netherlands). The self-adhesive electrodes (8x5 cm2 Pals Platinum © type, Axelgaard Manufacturing Co. Ltd, Fallbrook, CA, USA) were placed on the quadriceps muscle. The positives electrodes placed distally on the rectus anterior and vastus externus and negative electrodes were placed proximally on the rectus anterior and vastus internus. The over current program consisted of 8 seconds (s) of work (ON phase) and 8 seconds of rest (OFF phase). The overcurrent program in the ON phase had a rise time of 2 s, a hold time of 4 s and a fall time of 2 s. The intensity of the electric current was increased to the maximum perceived tolerance, achieving a clear contraction without producing fatigue.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrostimulation
Description: Consisting of the use of NMES (biphasic symmetrical pulse, bipolar mode, 50Hz frequency, pulse duration 300 μs at 1:1 ratio) (S82®; Enraf-Nonius BV, Rotterdam, The Netherlands). The self-adhesive electrodes (8x5 cm2 Pals Platinum © type, Axelgaard Manufacturing Co. Ltd, Fallbrook, CA, USA) were placed on the quadriceps muscle. The positives electrodes placed distally on the rectus anterior and vastus externus and negative electrodes were placed proximally on the rectus anterior and vastus internus. The over current program consisted of 8 seconds (s) of work (ON phase) and 8 seconds of rest (OFF phase). The overcurrent program in the ON phase had a rise time of 2 s, a hold time of 4 s and a fall time of 2 s. The intensity of the electric current was increased to the maximum perceived tolerance, achieving a clear contraction without producing fatigue.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood flow restriction therapy
Description: To attain partial vascular occlusion, a PTS ii portable tourniquet system (Delphi Medical, Vancouver, BC, Canada) with a corresponding size-specific tourniquet was placed around the patient's proximal thigh. This system allows for precise control of cuff pressure throughout training despite the changes in muscle volume that naturally occur while performing exercises. Total limb occlusion pressure (LOP) was identified by determining the pressure required to eliminate a detectable pulse using Doppler ultrasound. Partial vascular occlusion was achieved by setting the tourniquet to 80% of the LOP. This ensured that venous occlusion was obtained while still allowing arterial inflow and was personalized to each patient despite variations in thigh girth, cuff size, and systolic blood pressure. An Easy-Fit Tourniquet Cuff (Delfi Medical, Vancouver, VC, Canada) was used with the PTS ii system.
Study: NCT05608070

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% saline infusion at the rate of 83.3 ml/h.
Study: NCT05846932

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OTEE HORS
Description: 10 weeks of occupational therapy focused on teaching and practicing self-regulation skills, provided while participants are riding horses

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: OT Clinic
Description: 10 weeks of occupational therapy focused on teaching and practicing self-regulation skills, provided in a traditional clinic
Study: NCT05776420

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Food voucher
Description: A voucher of $65 (or $85 for people in larger households) that can be redeemed for food at grocery stores.
Study: NCT06321315

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Case-based instruction
Description: Case-based instruction will be applied to the students in the intervention group. Student Information Form, Critical Thinking Motivation Scale, Academic Motivation Scale and Knowledge Assessment Form will be . All students will receive classical in-class theoretical education about such as hemorrhages, hyperemesis gravidarum, oligohydramnios and urinary system diseases. In the intervention group, after the theoretical teaching of each subject within the scope of the Risky Pregnancy and Care course, cases prepared on the basis of the subject taught to the students will be applied. Student Information Form (13th and 14th questions), Critical Thinking Motivation Scale, Academic Motivation Scale, Knowledge Assessment Form and Visual Comparison Scale will be applied to all students as post-test data after case-based teaching of four topics.
Study: NCT05737303

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nab-paclitaxel combined with carboplatin
Description: Nab-Paclitaxel/carboplatin q3weeks Nab-Paclitaxel 260 mg/m² IV followed by carboplatin AUC（area under the curve） 5 IV Day1 Repeat every 21 days x 6 cycles Nab-Paclitaxel/carboplatin weekly Dose-dense Nab-Paclitaxel 100 mg/m2 IV followed by carboplatin AUC（area under the curve）2 IV Davs 1. 8, and 15 ·Repeat every 21 days x 6 cycles Paclitaxel 175 mg/m² IV followed by carboplatin AUC（area under the curve）5 IV Day·1Repeat every 21 days x 6 cycles~Paclitaxel weekly/carboplatin weekly Paclitaxel 60 mg/m2 followed by carboplatin AUC（area under the curve）2 IV Days 1.8. and 15: repeat every 21 days 6 cycles (18 weeks)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nab-paclitaxel combined with carboplatin
Description: Nab-Paclitaxel/carboplatin q3weeks Nab-Paclitaxel 260 mg/m² IV followed by carboplatin AUC（area under the curve） 5 IV Day1 Repeat every 21 days x 6 cycles Nab-Paclitaxel/carboplatin weekly Dose-dense Nab-Paclitaxel 100 mg/m2 IV followed by carboplatin AUC（area under the curve）2 IV Davs 1. 8, and 15 ·Repeat every 21 days x 6 cycles Paclitaxel 175 mg/m² IV followed by carboplatin AUC（area under the curve）5 IV Day·1Repeat every 21 days x 6 cycles~Paclitaxel weekly/carboplatin weekly Paclitaxel 60 mg/m2 followed by carboplatin AUC（area under the curve）2 IV Days 1.8. and 15: repeat every 21 days 6 cycles (18 weeks)
Study: NCT05982626

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 68Ga/131I-SGMIB-ZT-199
Description: 68Ga-SGMIB-ZT-199: PET imaging; 131I-SGMIB-ZT-199: SPECT imaging.
Study: NCT06469632

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator: Experimental Group 1
Description: Multimodal physiotherapy treatment composed of:~Therapeutic education about anatomy, physiology and pathophysiology of the abdomino-pelvic cavity, pelvic floor dysfunctions and risk factors, the concept of pain and its associated factors, as well as individual strategies to manage pain.~Specific PFM exercises performing different types of contractions aimed at improving proprioception, strength, resistance and relaxation capacity.~Conservative and invasive treatment of MPS active myofascial trigger points (MTP) will be treated by dry needling and Swiss technique. Latent MTP will be treated using the Swiss technique.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental: Experimental Group 2
Description: Multimodal physiotherapy treatment composed of:~Therapeutic education about anatomy, physiology and pathophysiology of the abdomino-pelvic cavity, pelvic floor dysfunctions and risk factors, the concept of pain and its associated factors, as well as individual strategies to manage pain.~Specific PFM exercises performing different types of contractions aimed at improving proprioception, strength, resistance and relaxation capacity.~Conservative and invasive treatment of MPS active myofascial trigger points (MTP) will be treated by dry needling and Swiss technique. Latent MTP will be treated using the Swiss technique.~Non-ablative radiofrequency: using capacitive superficial electrodes and resistive superficial and intravaginal electrodes.
Study: NCT04925128

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate Physical Activity + Conventional Physical Therapy
Description: Hot pack and TENS for 10 minutes at the affected shoulder. Passive shoulder mobilizations were performed initially at pain free range in anterior, posterior, and inferior direction (10 reps x 1 set).~Shoulder rolls, pendulum stretch, cross body arm stretch and towel stretch (10 reps x 1 set) were actively performed by the patient with-in limits of pain Moderate physical activity on treadmill, brisk walk was performed 5 days a week for 30 minutes at 4 mph speed (3-6 METs) with warm up for a 5 minutes at low speed and then at the end speed was also decreased for a 5 minutes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy
Description: Hot pack and TENS for 10 minutes at the affected shoulder. Passive shoulder mobilizations were performed initially at pain free range in anterior, posterior, and inferior direction (10 reps x 1 set).~Shoulder rolls, pendulum stretch, cross body arm stretch and towel stretch (10 reps x 1 set) were actively performed by the patient with-in limits of pain
Study: NCT06474052

Intervention type: DRUG
Intervention: Gelofusine 4%
Description: Gelofusine 4% 10 ml/kg is administered following anaesthesia induction in 30 minutes.
Study: NCT05285605

Intervention type: DRUG
Intervention: Ulipristal Acetate
Description: Ulipristal acetate 30mg x 1 dose as needed for unprotected intercourse
Study: NCT06599554

Intervention type: OTHER
Intervention: follow up scores
Description: The radiological reports will be read, analyzing when the bony consolidation of the fracture is reported in relation to the time elapsed since the operation.~The questionnaires will be submitted to all patients who have completed the course at 1 year.~All patients who sign the informed consent will be asked to complete the questionnaires either at the time of the follow-up visit by common clinical practice or by telephone, in the event that the patients have exceeded the 1-year follow-up
Study: NCT05120765

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The CONNECT Program
Description: The CONNECT Program is a 6-week, group-based, telephone-based, mental health intervention for socially isolated older adults. This group-therapy intervention is based on principles of Acceptance and Commitment Therapy (ACT). The group sessions take place once a week and they last 90 minutes each.
Study: NCT05091281

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intubation of the double lumen tube by Macintoch laryngoscope
Description: After induction of anesthesia insertion of the double lumen tube was done by Macintosh laryngoscope

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intubation of the double lumen tube by Glidescope videolaryngoscope
Description: After induction of anesthesia insertion of the double lumen tube was done by GlideScope® videolaryngoscope

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intubation of the double lumen tube by C-MAC®(D) videolaryngoscope
Description: After induction of anesthesia insertion of the double lumen tube was done by C-MAC®(D) videolaryngoscope
Study: NCT06490653

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Blood Stopper (Ankaferd)
Description: 5 ml of Ankaferd® will be sprayed through the bleeding side nostril and external nasal pressure will be performed for 10 minutes.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Blood Stopper (Ankaferd)
Description: 5 ml of Ankaferd® will be sprayed through the bleeding side nostril and external nasal pressure will be performed for 10 minutes.
Study: NCT06604819

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ozone gel placed after closed sinus lifting then implant placed simultaneously.
Description: The patient received closed sinus lifting using osteotomes then ozone gel is prepared. Pure olive oil was blasted with 25 μ/ml O3 gas for two days, or until the oil changed from a greenish-colored liquid to a whitish gel. The longevity Ext 120 ozone generator executed out this process then implants were placed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: closed sinus lifting using osteotomes with simultaneous implant placement
Description: The patient received closed sinus lifting using osteotomes with implant placed simultaneously.
Study: NCT06605339

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Virtual Reality Distraction
Study: NCT06606041

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dry Needling
Description: This. minimally invasive technique is based on the insertion of a sterile, low-caliber, monofilament needle, without the injection or extraction of any additional substances, into hyperirritable muscle nodules. There are two categories within this technique, based on the depth at which the needle is inserted: superficial needling (or the Baldry technique), in which the needle is inserted up to the subcutaneous cellular tissue overlying the myofascial trigger point (up to 10 mm); and deep needling, where the needle is inserted into the muscle with the intention of reaching the myofascial trigger point. Reaching the trigger point was the investigators goal. Regardless of the technique selected, the aim is to generate controlled micro spasms in the affected muscle area, alternating with periods of muscle relaxation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ischemic Compression
Description: Ischemic compression is a conservative, manual technique used on myofascial trigger points, in which pressure should be exerted between 30 and 90 seconds on these same areas. It is suggested that it leads to the normalization of the biomechanical properties of muscle fibers, restoring the muscle\&#39;s functional condition and probably reducing the risk of injury. Thus, the therapeutic effects include the stimulation of mechanoreceptors, with pain attenuation mainly due to the depletion of specific neurotransmitters and temporary obstruction of local blood flow (local ischemia), followed by a rapid influx of oxygenated blood to the area under pressure relief,(37) which will cause an increase in muscle metabolism.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cross Tapes
Description: Cross tapes, as the name implies, based on an equidistant intersection of three or four polyester tapes with a non-elastic adhesive acrylic coating, with the 3 lines oriented in a latero-medial direction. It is recommended that it be applied to the muscle area where the myofascial trigger point has been detected, at a 45º angle to the muscle fibers. Its application may have several purposes, such as muscle support, improving the stability of the fibers; pain relief, especially in areas where muscle tension and/or inflammation are present; aiding lymphatic drainage; promoting blood circulation. Before it is applied, the skin should be clean (disinfecting the area with alcohol) and dry, without any lotion or other ointments and the maximum period of use should not exceed 24 hours due to the risk of changes in position, either due to sweating or direct intervention by the patient himself.
Study: NCT06606093

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: DWP16001 Placebo
Description: 1 tablet, Orally, Once daily single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001 0.3mg
Description: 1 tablet, Orally, Once daily single dose
Study: NCT06602583

Intervention type: DIAGNOSTIC_TEST
Intervention: Standard Dose Coronary angiography
Description: The radiation exposure of this group would be collected from database of already done studies in the months prior to the initiation of the study (so as to prevent observer bias which may happen once the interventional cardiologist knows his inclusion in study, and may use a shorter or longer cine runs, thus influencing the outcomes). This would best represent the real-world data set, according to the routinely followed standard dose/ older low dose protocol.

Intervention type: DIAGNOSTIC_TEST
Intervention: New low dose angiography
Description: a comparative arm where the patients being once eligible for the study; would undergo angiography using the new low dose protocol.
Study: NCT05916274

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood and fecal samples
Description: Blood and fecal samples will be performed

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Coolonic biopsies
Description: colonic biopsies will be analysed
Study: NCT04859205

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Participants will have access to the SUPPORT-Pro self-guided online training platform addressing many aspects of type 1 diabetes care. The SUPPORT-Pro content was developped by a team of health professionals specialized in type 1 diabetes as well as patient partners. It's content is regularly updated, evidence-based and divided into 6 categories (medication, blood glucose monitoring, diet, physical activity, hypo and hyperglycemia, health and other particularities). In each category, users can pick between 3 levels (beginner, intermediate and advanced) according to their level of confidence and knowledge.~Participants will be asked to fill out questionnaires at baseline, 3-month, and 12-month of the intervention which include the following: Eligibility assessment, identification, background, confidence, platform satisfaction.
Study: NCT05374694

Intervention type: DIAGNOSTIC_TEST
Intervention: Physiological invasive coronary evaluation
Description: Performance of FFR, IMR and acetylcholine test (Only patients in groups 3 and 4 will undergo the acetylcholine test)

Intervention type: DIAGNOSTIC_TEST
Intervention: Physiological invasive coronary evaluation
Description: Performance of FFR, IMR and acetylcholine test (Only patients in groups 3 and 4 will undergo the acetylcholine test)

Intervention type: DIAGNOSTIC_TEST
Intervention: Physiological invasive coronary evaluation
Description: Performance of FFR, IMR and acetylcholine test (Only patients in groups 3 and 4 will undergo the acetylcholine test)

Intervention type: DIAGNOSTIC_TEST
Intervention: Physiological invasive coronary evaluation
Description: Performance of FFR, IMR and acetylcholine test (Only patients in groups 3 and 4 will undergo the acetylcholine test)

Intervention type: DIAGNOSTIC_TEST
Intervention: Physiological invasive coronary evaluation
Description: Performance of FFR, IMR and acetylcholine test (Only patients in groups 3 and 4 will undergo the acetylcholine test)
Study: NCT04969666

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IPED2015
Description: Active treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IPED2015
Description: Active treatment

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo