TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05988606

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 15 minutes of high-intensity interval training
Description: Participants completed an 8 min warm-up and 1 round of high-intensity interval training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 15 minutes of high-intensity interval training
Description: Participants completed an 8 min warm-up and 1 round of high-intensity interval training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 43 minutes of high-intensity interval training
Description: Participants completed an 8 min warm-up and 5 rounds of high-intensity interval training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 43 minutes of high-intensity interval training
Description: Participants completed an 8 min warm-up and 5 rounds of high-intensity interval training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hot environment
Description: Participants exercised in a hot environment, \~ 35 °C, \~40% relative humidity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hot environment
Description: Participants exercised in a hot environment, \~ 35 °C, \~40% relative humidity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temperate environment
Description: Participants exercised in a temperate environment, \~ 22 °C, \~40% relative humidity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temperate environment
Description: Participants exercised in a temperate environment, \~ 22 °C, \~40% relative humidity.
Study: NCT05952609

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Surefil One
Description: Ion-releasing restoration

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cention N
Description: Ion-releasing restoration

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bulkfil resin composite
Description: resin composite (No ion-release)
Study: NCT05996913

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Imagery rescripting
Description: The current project aims to explore the feasibility of intervention featuring imagery rescripting (ImRs) and grounding in the management of somatic flashbacks amongst this population. ImRs was developed as a method to help activate a traumatic memory, bring corrective information into the memory, create a more favourable outcome to the memory and to support the participant to discover and express inhibited trauma-related emotional responses (Arntz \& Weertman, 1999).
Study: NCT05600777

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-5937
Description: Oral administration of BLU-5937 Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-5937
Description: Oral administration of BLU-5937 Tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral administration of matching placebo for BLU-5937 Tablets
Study: NCT05460091

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PTech Device
Description: High-frequency vibration device used on regular basis in orthodontics

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: PTech Sham Device
Description: sham device (does not vibrate)
Study: NCT05741554

Intervention type: OTHER
Intervention: Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.
Description: Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery

Intervention type: OTHER
Intervention: Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.
Description: Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery
Study: NCT05166837

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection
Study: NCT05482750

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance training in the fasted state
Description: On the first day of evaluations, the subjects will perform the basal metabolic rate (BMR) analysis, as well as familiarization with the neuromuscular tests. After the preliminary tests, the volunteers will perform the pre-intervention procedures. Assessments of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be performed. In addition, instruments related to dietary control and physical activity level will be applied. Subsequently, in a randomized manner, participants will be allocated to one of two different interventions. During the intervention (8 weeks), the adherence to the standard diet will be verified, as well as body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be reassessed. After the 12 weeks of intervention, the volunteers will perform the evaluations referring to the post-intervention moment, following the same steps of the pre-intervention collections.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance training in the fed state
Description: On the first day of evaluations, the subjects will perform the basal metabolic rate (BMR) analysis, as well as familiarization with the neuromuscular tests. After the preliminary tests, the volunteers will perform the pre-intervention procedures. Assessments of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be performed. In addition, instruments related to dietary control and physical activity level will be applied. Subsequently, in a randomized manner, participants will be allocated to one of two different interventions. During the intervention (8 weeks), the adherence to the standard diet will be verified, as well as body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be reassessed. After the 12 weeks of intervention, the volunteers will perform the evaluations referring to the post-intervention moment, following the same steps of the pre-intervention collections.
Study: NCT06126250

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Power sonic toothbrush
Description: Subjects will brush twice daily for 30 seconds using a fluoride toothpaste.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Manual toothbrush
Description: Subjects will brush twice daily for 2 minutes using a fluoride toothpaste.
Study: NCT04976582

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dry needle
Description: modalities including transcutaneous electrical nerve stimulation (TENS); electrical muscle stimulation (EMS); and interferential current (IFC). Physical agents including ultrasound, hot packs, and cold packs. Exercise including McKenzie exercises) will be administered.
Study: NCT06193122

Intervention type: DEVICE
Intervention: Ultrasound imaging 3D and Spectroscopy
Description: Ultrasound imaging and spectroscopy will consist of collecting three dimensional data. Regions of interest in each of the tumour images and in the adjacent normal tissue will be selected for analysis.
Study: NCT05044299

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Isoped
Description: Isoped is a mechanical device allowing movement of lower extremities in a forward and backward motion, with phone-based app to control resistance load

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Isoped
Description: Isoped is a mechanical device allowing movement of lower extremities in a forward and backward motion, with phone-based app to control resistance load
Study: NCT06099080

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SM-020 gel 1.0%
Description: Subjects will apply the investigational product twice daily for 4 consecutive weeks. Subjects will be followed for 12 weeks post final application for a total of approximately 16 weeks of required participation in the study.
Study: NCT05971706

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ozone therapy using a device (Ozone DTA Ozone Generator, Denta Tec Dental AS, Norway)
Description: Ozone therapy procedures will be performed immediately after non-surgical periodontal treatment and three times (every third day) within one week using a device equipped with a periodontal tip according to equipment producer recommendations. The periodontal tip will be halted 1 mm short of the pocket depth. Ozone will be applied only to the pockets; which depth is equal to or greater than 5 mm. Ozone application time to the pockets will be 30 seconds at a fixed concentration of 2,100 ppm (80% oxygen) through a connected handpiece.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-surgical periodontal treatment
Description: Non-surgical periodontal treatment consists of oral hygiene instructions, full mouth supragingival scaling using hand instruments, ultrasonic devices, polishing, and subgingival debridement under local anesthesia with sharp Gracey and Universal curettes and ultrasonic instruments in a single appointment.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non-surgical periodontal treatment
Description: Non-surgical periodontal treatment consists of oral hygiene instructions, full mouth supragingival scaling using hand instruments, ultrasonic devices, polishing, and subgingival debridement under local anesthesia with sharp Gracey and Universal curettes and ultrasonic instruments in a single appointment.
Study: NCT05788471

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional Treatment
Description: It consists of Superficial heat, Ultrasound therapy and stretching exercise to lumbrical muscles of the hand.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional Treatment
Description: It consists of Superficial heat, Ultrasound therapy and stretching exercise to lumbrical muscles of the hand.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurodynamic mobilization
Description: It is the mobilisation of the nervous system as an approach to physical treatment of pain. The treatment and or assessment relies on influencing pain physiology via the mechanical treatment of neural tissues and non-neural structures surrounding the nervous system.
Study: NCT05549921

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NY-ESO-1(TCR Affinity Enhancing Specific T cell Therapy)
Description: NY-ESO-1(TCR Affinity Enhancing Specific T cell Therapy)
Study: NCT04527900

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: carboplatin and paclitaxel
Description: carboplatin and paclitaxel 5-6 cycles (dosage per standard of care according to treating oncologist)

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: pelvic IMPT (Intensity Modulated Proton Therapy)
Description: whole pelvis will receive a total dose of 4500 cGy in 25 fractions to 5040 cGy in 28 fractions
Study: NCT05983081

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Injection Treatment
Description: Physical Therapy
Study: NCT05667337

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CLP-PEG-MPC
Description: Implantation of a 500 um thick biosynthetic corneal implant utilizing DALK surgical technique

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Human donor cornea penetrating keratoplasty
Description: Implantation of a human donor cornea graft utilizing PKP surgical technique
Study: NCT05330104

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Ecological Momentary Assessment
Description: mEMA is a tool that allows for scheduled or triggered surveys to assess a participant's CIPN symptoms and/or fall risk
Study: NCT06287177

Intervention type: DRUG
Intervention: Inclisiran
Description: Injection
Study: NCT05503238

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Skin-to-skin contact
Description: Preterm infants will receive maternal-infant skin-to-skin contact at least 1 continuous hour everyday from infant 3 days of life until discharge, and other nursing care will be same as the routine group. During skin-to-skin contact, place naked baby only with diaper on the mother's bare chest in an upright position and tilt the baby's head to one side in a slightly extended position to keeps the airway open, cover the infant with a blanket to keep them warm. A neonatal nurse will be stay with mother and infant to observe and support.

Intervention type: OTHER
Group type: OTHER
Intervention: Routine care
Description: Preterm infants will receive standard nursing care provided by neonatal nurses in accordance with hospital principles during hospitalization.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine care
Description: Preterm infants will receive standard nursing care provided by neonatal nurses in accordance with hospital principles during hospitalization.
Study: NCT06160934

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: T1D Parent Check-in
Description: The Type 1 Diabetes (T1D) Parent Check-in is an innovative, 3-session, T1D-specific intervention for parents of newly diagnosed children and adolescents that can be delivered via telehealth. The T1D Parent Check-in is an adaptation of The Parent Check-In, a brief, prevention-based parenting intervention developed by Grolnick, Levitt, Caruso, \& Lerner (2021). The T1D Parent Check-in is designed to promote parenting skills on dimensions of autonomy support, structure and involvement that facilitate children's adjustment and motivation, and integrates skills from cognitive-behavioral therapy, customized to be highly relevant to families with a child 6-12 months from new diagnosis of T1D. The intervention is intended to promote diabetes-related resilience and positive psychological and medical outcomes among families of children with T1D.
Study: NCT05570461

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Modified Constraint-Induced Movement Therapy
Description: Experimental group will receive Modified Constraint-Induced Movement Therapyand traditional physical therapy to the impaired upper limb based on the repetitive training of functional activities and behavioral shaping and a task-oriented approach, while the unaffected arm of subjects in the mCIMT group will be constrained by wearing a mitten during the treatment session and for 3 hours/day outside the therapy hours, 6(six) days/week for two weeks by an experienced Physical therapist.The time duration for Group A will be 40 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Constraint-Induced Movement Therapy
Description: Experimental group will receive Modified Constraint-Induced Movement Therapyand traditional physical therapy to the impaired upper limb based on the repetitive training of functional activities and behavioral shaping and a task-oriented approach, while the unaffected arm of subjects in the mCIMT group will be constrained by wearing a mitten during the treatment session and for 3 hours/day outside the therapy hours, 6(six) days/week for two weeks by an experienced Physical therapist.The time duration for Group A will be 40 minutes.
Study: NCT03843008

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Melatonin
Description: Participants in the Melatonin Group will receive 3mg of melatonin each evening for up to seven days for a maximum total of 21mg of melatonin.
Study: NCT05396599

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Model DIU
Description: Subjects will be randomized to a treatment group (masked) in ratio 1:1:1. Surgeons will perform standardized, small-incision, cataract surgery and implant the study lenses using a JJSV-validated insertion system qualified for use with the lens to be implanted.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Model DFW
Description: Subjects will be randomized to a treatment group (masked) in ratio 1:1:1. Surgeons will perform standardized, small-incision, cataract surgery and implant the study lenses using a JJSV-validated insertion system qualified for use with the lens to be implanted.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Model ZCT
Description: Subjects will be randomized to a treatment group (masked) in ratio 1:1:1. Surgeons will perform standardized, small-incision, cataract surgery and implant the study lenses using a JJSV-validated insertion system qualified for use with the lens to be implanted.
Study: NCT06496646

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reminders
Description: We will send daily text messages to participants for 12 weeks reminding them to take their antidepressant medication. These reminders will be tailored, personalized and patient-centric, grounded in behavioral economics principles.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reminders
Description: We will send daily text messages to participants for 12 weeks reminding them to take their antidepressant medication. These reminders will be tailored, personalized and patient-centric, grounded in behavioral economics principles.
Study: NCT05552417

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pectointercostal facial plan block
Description: Pectointercostal facial group (PI) (n=--) where --children will have bilateral Pectointercostal Block.
Study: NCT05822765

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine concentration of 1:1000000
Description: Tumescence fluid contained Epinephrine concentration of 1:1000000 (one ampoule 1 mg per liter) lidocaine 500 mg and sodium bicarbonate 8.4% 10 ml per liter

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine concentration of 1:500000
Description: Tumescence fluid contained Epinephrine concentration of 1:500000 two ampoule 2 mg/liter with same lidocaine and bicarbonate dose. lidocaine 500 mg and sodium bicarbonate 8.4% 10 ml per liter
Study: NCT05692336

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: vestibular training
Description: balance training in the form of vestibular training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dual task training
Description: balance training in the form of dual task training
Study: NCT05675644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drospirenone-only pill
Description: Single dose based on adaptive dose-finding design

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drospirenone-only pill
Description: Single dose based on adaptive dose-finding design
Study: NCT06496646

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Incentives
Description: In addition to daily text messages, participants will receive financial incentives for 6 weeks based on contingency management principles. Participants assigned to the Reminders and Incentives arm of the study will receive a $2/day incentive, increasing by $1/day conditioned on each week that they consistently take their antidepressant over the first 6 weeks, for a maximum total payment of $189 ($2, $3, $4, $5, $6, $7 in weeks 1 through 6, respectively).
Study: NCT05969847

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: split-course hypofraction radiotherapy
Description: After reaching a cumulative radiotherapy dose of 25Gy in the entire pelvic cavity (PTV1), the treatment field was subsequently narrowed to solely focus on the primary tumor (PTV2), with a total dose of 35Gy administered. All patients will undergo fractionated radiotherapy, following a regimen of 7Gy per fraction, delivered every 3 weeks for five cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAPOX
Description: Drug: Oxaliplatin,130mg/m2，ivgtt，d1,for 6 cycles. Drug: Capecitabine,1000mg/m2，po，bid，d1-14, for 6 cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envafolimab
Description: Envafolimab is administered by subcutaneous injection. The recommended dose is 300 mg per 3 weeks (Q3W) for 6 cycles.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Local excision
Description: Local full-thickness resection is employed for patients with clinical complete response (cCR) or near-clinical complete response (ncCR) following TNT.
Study: NCT05155189

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: C-CAR031
Description: Targeting GPC3 armored CART cell injection (C-CAR031)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: C-CAR031
Description: Targeting GPC3 armored CART cell injection (C-CAR031)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: C-CAR031
Description: Targeting GPC3 armored CART cell injection (C-CAR031)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Tyrosine kinase inhibitors

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1(L1) monoclonal antibody
Description: Immune checkpoint inhibitors, ICIs
Study: NCT05799248

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rhPSMA-7.3 (18F)
Description: Patients will receive a dose with an administered activity of 8 mCi (296 MBq) ± 20% of rhPSMA-7.3, delivered as an IV bolus injection with a 10 mL fast 0.9% sodium chloride flush, followed by PET imaging.
Study: NCT05676268

Intervention type: PROCEDURE
Intervention: Implant-supported fixed dental prostheses with cantilever extension
Description: Healthy patients in need of replacement of missing teeth with dental implants supporting partial fixed dental prostheses with cantilever extensions
Study: NCT04801056

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TB006
Description: TB006 monoclonal antibody

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo i.v. infusion
Study: NCT05466201

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eltrombopag 25 MG Oral Tablet
Description: Since thrombopoietin receptor agonists (TPO-RAs) have never been regularly used for promotion of cell engraftment post hematopoietic stem cell transplantation HSCT), we design this eltrombopag intervention to evaluate the safety and efficacy of TPO-RAs post HSCT.

Intervention type: DRUG
Group type: OTHER
Intervention: Supportive care
Description: Patients receive transfusion of blood products, including platelets and red blood cells.
Study: NCT05842356

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communication Technique 2
Description: A new communication technique.
Study: NCT05912790

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: eyeTube
Description: Implantation of a drainage device in the eye, in combination with the eyeWatch implant