TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06727578

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: of intrapleural saline irrigation with CLR irrigator
Description: patients will have a CLRTM port and CLRTM irrigator (CLR Medical, Calverton, MD, USA) added to their chest tube and atrium circuit to facilitate pleural irrigation.
Study: NCT06729151

Intervention type: DRUG
Intervention: Onabotulinum toxin A
Description: Cystoscopic injection of Onabotulinum toxin A per standard clinic protocol.

Intervention type: BEHAVIORAL
Intervention: Conservative management (dietary and behavioral)
Description: Dietary and behavioral modifications consistent with recommendations from the American Urogynecological Society
Study: NCT06729515

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PCA
Description: Immediately post-surgery, patients in the PCA group received a programmed PCA infusion (YG-B-3; Jiangsu Yaguang Medical Device Co., Ltd., China) containing either ketorolac (180 mg) or sufentanil (200 µg) in 100 mL, delivered as a 2 mL/h basal infusion with 0.5 mL boluses; lockout interval: 15 min.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CEA
Description: Following epidural catheter placement in the operating room, the CEA group received an initial bolus of 2% lidocaine (3 mL). Once sensory blockade was confirmed, continuous epidural infusion of 0.1% ropivacaine (8 mL/h) commenced.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RISS
Description: RISS blocks were performed at the T4-T10 level under ultrasound guidance (EPIQ5 with L12-4 linear 7.5 MHz transducer; Philips Healthcare, Best, Netherlands). A 19-gauge, 40-cm catheter was advanced 3-5 cm beyond the needle tip into the subserratus plane, its position confirmed by injecting 5 mL of 0.2% ropivacaine. A further 15 mL of 0.2% ropivacaine was then administered. The catheter was connected to a PCA pump programmed to deliver a 7 mL/h basal infusion with 2 mL boluses; lockout interval: 30 min.
Study: NCT06729411

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Minimal Offloading dressing
Description: Metatarsal minimal offloading dressings (MODs) are standard offloading devices that are gaining attention. MODs offload a specific ulcerated area and could reduce variability when applying the device onto the skin. MODs are new predesigned devices that do not require any further adaptation or clinician skills and can be directly applied to an ulcerated metatarsal head using a non-irritating adhesive.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Felted foam
Description: The felted padding used in the control group was made out of semi-compressed wool felt with an adhesive backing (Herbitas lab, 46134 Foios-Valencia, Spain). The padding thickness was 15 mm on the whole foot, and similar apertures to those used with the other offloading device were made to accommodate the sites of plantar ulceration.
Study: NCT06728475

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: virtual reality
Description: In Xbox, we will choose suitable games that aim to improve upper limb function like boxing, Darts, tennis, goalkeeping, basketball, disc throwing, balling, and volleyball.~The Kinect sensor has the advantage of auto adjustment of its camera according to the child's position and height that's to say the child can perform the game in sitting or standing according to their abilities.~They will receive 30 minutes of VR intervention in addition to the time required for the designed physical therapy program.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: mirror therapy
Description: Mirror Therapy A mirror of 30 × 20 inches was used for the MT, which was large enough to cover the entire affected limb while still allowing the reflection of the non-affected limb to be seen. The child was seated in a chair with the forearms resting on the table. In the mid-sagittal plane, the mirror box was positioned at an angle of 70° to 80° to the trunk. The affected limb was placed behind the mirror. The child was asked to perform the exercises bilaterally and symmetrically as much as possible. Even if the affected side did not move easily or fully, the child was advised to synchronize the motions with both hands and arms. The researcher constantly reminded the child to concentrate on the movement of the non-affected limb in front of the mirror, which helped to increase the mirror illusion

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: virtual reality with mirror therapy
Description: group C will receive combined effect of both techniques (virtual reality and mirror therapy)
Study: NCT06729606

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Aviptidil
Description: Administered by IV infusion over 12 hours per day for 3 days. The Day 1 infusion rate is 50 pmol/kg/hr, the Day 2 infusion rate is 100 pmol/kg/hr, and the Day 3 infusion rate is 150 pmol/kg/hr.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Aviptidil Placebo
Description: Commercially available 0.9% sodium chloride solution. Administered by IV infusion over 12 hours per day for 3 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Corticosteroid
Description: In line with NIH treatment guidelines, corticosteroids such as dexamethasone, prednisone, methylprednisolone or hydrocortisone may be administered as SOC.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Corticosteroid
Description: In line with NIH treatment guidelines, corticosteroids such as dexamethasone, prednisone, methylprednisolone or hydrocortisone may be administered as SOC.
Study: NCT06472479

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LCAR-M61S cells preparation
Description: Biological:~LCAR-M61S or LCAR-M61D cells intravenous infusion; Prior to infusion of the LCAR-M61S and LCAR-M61D cell preparation, Subjects will receive a conditioning premedication regimen consisting of cyclophosphamide and fludarabine.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LCAR-M61D cells preparation
Description: Biological:~LCAR-M61S or LCAR-M61D cells intravenous infusion; Prior to infusion of the LCAR-M61S and LCAR-M61D cell preparation, Subjects will receive a conditioning premedication regimen consisting of cyclophosphamide and fludarabine.
Study: NCT06729307

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral ondansetron and dyclonine hydrochloride mucilage
Description: Patients will take 8 mg oral ondansetron 2 hours prior to EGD process in addition to dyclonine hydrochloride mucilage to be gurgled 15 minutes prior to EGD process.
Study: NCT06390098

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASN51
Description: ASN51 formulation for oral capsule
Study: NCT06729307

Intervention type: DRUG
Group type: OTHER
Intervention: Dyclonine hydrochloride mucilage
Description: Patients will be instructed to gurgle 10 mL of dyclonine chloride mucilage (0.01 g/mL) and gurgle for 1 minute 15 minutes prior to endoscopic process.
Study: NCT06728345

Intervention type: DRUG
Intervention: Rimegepant
Description: Female migraine patients take Rimegepant (75mg QOD) as their regular prophylactic treatment of migraine for 12 weeks
Study: NCT06115018

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Palatal surgery
Description: Palate surgery has evolved from the ablative partial palate resections, which favored the removal of the soft tissue that obstructed the upper airway (UA), to more recent innovative reconstructive procedures that not only address the level of palatal obstruction, but the type of palatal or lateral pharyngeal wall collapse.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Oropharyngeal rehabilitation
Description: Oropharyngeal rehabilitation (OPR) focus on the upper airway muscle including tongue muscle, palatal muscles and paryngeal muscles. The OPR for the treatment groups included three 30-minute sessions of OPR per day, and the exercise would be performed 3-5 days per week for 3 months. The performance of the home exercise will also be recorded by the force-sensing resistor. In addition to home exercise sessions, there will also be twice-weekly clinical visits to adjust the contents of OPR program and monitor training progress.
Study: NCT05053607

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Digital Health Coaching Program
Description: consisting of weekly calls and delivery of evidence-based content across health and wellness domains (e.g. nutrition, exercise, physical, emotional and financial health) up to 4 times weekly via text, email or mobile application.
Study: NCT06115018

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Palatal surgery combined oropharyngeal rehabilitation
Description: Participants will receive palatal surgery and post-surgery oropharyngeal rehabilitation (OPR). The palatal surgery and OPR describe as above.
Study: NCT06520956

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video based exercise group
Description: In each session, 2 videos will be applied and each will be repeated 2-3 times, with a 3-minute rest break between each video. The total session will last an average of 20-30 minutes and 16 sessions of physical activity will be performed twice a week for a total of 8 weeks.
Study: NCT04987073

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: skin biopsy
Description: A skin biopsy to cultivate fibroblasts.
Study: NCT05053607

Intervention type: DEVICE
Group type: OTHER
Intervention: Fitbit
Description: A wrist-worn activity tracker allowing for the capture of physical activity, including but not limited to step-count and minutes of activity, to be captured daily.
Study: NCT05947032

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised endurance exercise training + Patient Education
Description: ENDURANCE TRAINING:~Treadmill Walking:~Frequency: 15 to 20 sessions for 3 to 5 days per week. Intensity: 40% to 60% of HRR Time: 15 Min Type: aerobic training~Recumbent Bike:~Frequency: 15 to 20 sessions for 3 to 5 days/week. Intensity: 40% to 60% HRR Time: 15 Min Type: aerobic training~+ Patient Education

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home exercises + Patient Education
Description: HOME EXERCISES:~CONVENTIONAL Treatment:~Walking:~Frequency: 2 times/ day Intensity: as tolerated Time: 30 Min Type: aerobic training~Stair climbing:~Frequency: 1 flight/ day Type: aerobic training~+ Patient Education
Study: NCT06078293

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based Exercise Program
Description: 12-week home-based exercise program that involves individualized exercise prescription and motivational health coaching calls.
Study: NCT05867823

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OcuApp
Description: The participants will have instaled a mobile aplication (OcuApp) by a member of the researchs team who will teach them how to use it. The person must register the activities they carry out throughout a week and mark each one of them with a punctuation (from 1 to 5) related to the meaning of the following dimensions: identity, pleasure, competence, importance and value of the activity by other people.The application also allows to collect other information such as where the activity takes place, its duration, and the people with whom it is carried out. Also, at the end of the week, the application will ask users about their perceived occupational balance. All the information registered in the mobile application will be returned to the person in a dynamic and understandable way. Based on this, the person can establish two goals to accomplish. In this sense, OcupApp will offer personalized recommendations based on the objectives to be achieved related to the dimensions of meaning.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Three-part work
Description: The intervention on the control group will focus on offering to the participants an informative three-part work on the positive effects of performing activities to control anxiety and depression. After providing this information, any doubts in this regard will be answered.
Study: NCT05711602

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates
Description: raining based on a basic level Pilates exercise program will be as follows: A duration of weeks with a frequency of 2 sessions a week and with a duration of 55 minutes each. The exercises to be performed will be divided into three distinct phases: warm-up, lasting 15 minutes; Main part with a duration of 30 minutes and the return to calm, based mostly on stretching and with a duration of 10 minutes. The repetitions of the exercises will be between 5 and 10 according to the difficulty.
Study: NCT05169398

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EUS-guided hepaticogastrostomy
Description: EUS-guided hepaticogastrostomy would be performed with the MG-biliary stent (Niti-S, Taewoong Medical, Gyeonggi-do, Korea)
Study: NCT05240742

Intervention type: OTHER
Intervention: no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and aggregated when possible) in 7 existing cohorts
Description: (Clinical) baseline and follow-up data will be collected in the 7 existing cohorts. These data will be aggregated (when possible). The CORFU analyses will be conducted based on the aggregated data.

Intervention type: OTHER
Intervention: no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and aggregated when possible) in 7 existing cohorts
Description: (Clinical) baseline and follow-up data will be collected in the 7 existing cohorts. These data will be aggregated (when possible). The CORFU analyses will be conducted based on the aggregated data.
Study: NCT06455735

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-JH04
Description: Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-JH04. Tracer doses of 68Ga-JH04 will be used to detect tumors by PET/CT.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI/18F-FDG
Description: Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-FAPI or 3.7 MBq (0.1 mCi)/Kg 18F-FDG. Tracer doses of 68Ga-FAPI/18F-FDG will be used to detect tumors by PET/CT.
Study: NCT05559970

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inhalational sedation
Description: Inhalational sedation with isoflurane for 12 hours

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Convention sedation
Description: Conventional sedation receiving analgosedation with fentanyl
Study: NCT05791071

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Floreo VR Building Social Connections
Description: Floreo's VR platform consists of a VR headset and wireless tethered VR screens (iPhones) and tablets (iPads) that are seamlessly linked in real time, allowing the therapist (or monitor) to set up lessons, change the interactive environment, and provide live verbal and VR-based guidance, feedback, and rewards to users. The lessons that will be implemented in this intervention are aimed at targeting social skills such as communication, joint attention, and social interactions.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: This condition will contain the same VR headset and wireless tethered VR screens (iPhones) and tablets (iPads) as the intervention condition, but instead of social skill lessons, only non-intervention, active VR videos such as underwater fish swimming will be shown.
Study: NCT04971603

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: All acupuncture operations were done by registered Chinese medicine practitioner. Sterile, disposable acupuncture needles (0.25mmin diameter and 40mmin length) were used, which were purchased from HuaTuo acupuncture instrument.~Principal points: Neiguan (PC 6) \*, Sanyinjia (SP 6) \*, Weizhong (BL 40) \*, Baihui (GV 20), Shuigou (GV 26) \*, Zusanli (ST 36) \*, Quchi (LI 11) \*, Waiguan (TE 5) \*, Hegu (LI 4) \*, Huantiao (GB 30) \*, Yanglingquan (GB 34)\* (Grading of recommendation: C, level of evidence: IV).~Supplementary points: If upper limbs hemiplegia occurs, add Jianliao (TE 14) and Shousanli (LI 10); if lower limbs hemiplegia occurs, add Xuanzhong (GB 39) and Taichong (LR 3); if a deviation of the mouth or tongue occurs, add Dicang (ST 4) and Jiache (ST 6).
Study: NCT04805333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemisia annua 450mg
Description: Artemisia annua will be self-administered via a preparation of decaffeinated coffee.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemisia annua 900mg
Description: Artemisia annua will be self-administered via a preparation of decaffeinated coffee.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemisia annua 1350mg
Description: Artemisia annua will be self-administered via a preparation of decaffeinated coffee.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemisia annua 1800mg
Description: Artemisia annua will be self-administered via a preparation of decaffeinated coffee.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemisia annua - recommended phase II dose
Description: Artemisia annua will be self-administered via a preparation of decaffeinated coffee. The dose for this cohort will be based on analysis of previous cohorts.
Study: NCT06023693

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: i-Sleep & BioClock
Description: Module 1 Psychoeducation about normal sleep and insomnia, Psychoeducation on the biological clock: the circadian rhythm, chronotypes, zeitgebers, importance of light behaviour Basic sleep hygiene: information about behaviours that are known to promote or impede sleep e.g. performing physical exercise or the use of caffeine Module 2 Sleep restriction and stimulus control: patients are taught to use the bedroom only to sleep and to restrict the time in bed to the average amount of night-time sleep Module 3 Worrying and relaxation: audio files with progressive muscle relaxation exercises are offered and techniques to stop worrying (e.g. thought blocking, evaluation and worry time) Module 4 Erroneous cognitions about sleep: the basics of cognitive behavioural therapy are explained and the most common erroneous ideas about insomnia are discussed Module 5 Summary and plan for the future

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online Psychoeducation
Description: Online psychoeducation about sleep and the biological clock, basic sleep hygiene
Study: NCT05759572

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apatinib
Description: TKI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dalpiciclib
Description: CDK4/6 inhibitor

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dalpiciclib
Description: CDK4/6 inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fulvestrant/AI
Description: Endocrine therapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fulvestrant/AI
Description: Endocrine therapy
Study: NCT05719168

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Body Surface Gastric Mapping
Description: 64-channel electrode array placed on the outer abdomen

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Body Surface Gastric Mapping
Description: 64-channel electrode array placed on the outer abdomen
Study: NCT06232096

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBS314 Injection
Description: Phase Ia: The patients confirming to the eligibility criteria will be assigned to 1 of the 7 dose groups (0.03/0.09/0.3/0.9 mg \~ 0.3/1.5/9.0/60 mg, respectively) based on the sequence of inclusion. Each patient will receive MBS314 as per the schedule specified in the respective arms.~Phase Ib/Ⅱ: Based on the results of Phase Ⅰa, 1 or 2 recommended doses will be selected for Phase Ⅰb. Recommended Phase II Dose (RP2D) will be selected for Phase Ⅱ.
Study: NCT06531993

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pectin
Description: Using pectin as tablets 600 mg per day for 6 months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pectin
Description: Using pectin as tablets 600 mg per day for 6 months
Study: NCT06489405

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Horticultural practices
Description: The first week of the program was 'Getting to know horticultural practices', the second week was 'Painting pots', the third week was 'Planting vegetable seedlings', the fourth week was 'Preparing compost', the fifth week was 'Making pressed flowers' and the sixth week was 'Harvesting vegetables'.
Study: NCT04590118

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: it-hMSC
Description: Single intravenous infusion of it-hMSC for ischemic stroke patients

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single intravenous infusion of 1 ml/kg placebo
Study: NCT06456385

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
Description: The intervention applied is called transcutaneous auricular vagus nerve stimulation (taVNS) which administers electrical stimulation at the ear which targets the auricular branch of the vagus nerve.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Auricular Stimulation
Description: The sham auricular stimulation administers electrical stimulation at the ear lobe which has less auricular branch of the vagus nerve.