TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05367102

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supporting Healthy Relationships program
Description: The investigator will provide the following 4 activities: 1) marriage and relationship education \[using a modified version of the empirically supported Loving Couples, Loving Children (LCLC); 2) pre-marital education and marriage skills; 3) marriage enhancement and marriage skills for married couples; and 4) divorce reduction and relationship skills.~All couples will be expected to participate in 24 hours of core relationship education workshops (including parenting education). Since parental financial support represents a core element of family stability, relationship education workshops will address motivation for providing financial support through employment for all couples (employed and unemployed) as well as how to manage conflicts over money. All couples will be invited to supplemental workshops (with couples from other cohorts) on topics of specialized interest, including employment services and financial literacy (i.e. budgeting, debt, etc.)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supporting Healthy Relationships program
Description: The investigator will provide the following 4 activities: 1) marriage and relationship education \[using a modified version of the empirically supported Loving Couples, Loving Children (LCLC); 2) pre-marital education and marriage skills; 3) marriage enhancement and marriage skills for married couples; and 4) divorce reduction and relationship skills.~All couples will be expected to participate in 24 hours of core relationship education workshops (including parenting education). Since parental financial support represents a core element of family stability, relationship education workshops will address motivation for providing financial support through employment for all couples (employed and unemployed) as well as how to manage conflicts over money. All couples will be invited to supplemental workshops (with couples from other cohorts) on topics of specialized interest, including employment services and financial literacy (i.e. budgeting, debt, etc.)
Study: NCT05704881

Intervention type: DIAGNOSTIC_TEST
Intervention: End-Tidal CO2 measurement during COPD exacerbation
Description: The EtCO2 will be measured at the emergency reception during assessment of vital signs by the nurse with the help of a mask or oxygen glasses measuring EtCO2. The patient will then be treated conventionally according to current international recommendations. The physician in charge of the patient will be blinded to this measurement. The outcome will be the initiation of invasive or non-invasive ventilation (NIV) within the first 24 hours of admission to the emergency department, as indicated by the physician in charge of the patient.
Study: NCT06007937

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lorlatinib
Description: Lorlatinib 100 mg orally daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ramucirumab
Description: Ramucirumab 10 mg/kg intravenous infusion once every three weeks is a tolerable and safe dose.
Study: NCT04418921

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-regulation: MRehab - Un colegio emocionante, clinical trial with non-immersive virtual reality
Description: The principles of the programme will be based on the following premises for children with ASD: 1) Strengthening communicative attempts; 2) Choose the most natural contexts possible; 3) Establish structured and predictable routines and environments; 4)Visually support information; 5) Adapting our language to the understanding level of the child. On the difficulty of interpreting and responding to social emotions and cues, games of perspectives are of great interest, where the child and therapist describe the same object from different perspectives, beliefs (guess that may be in this box), games with social stories, which are short stories that use pictograms, to help understand especially situations with social ambiguity: 1) describing what happens; 2) orienting the action, indicating to the child what to do in that situation; 3) anticipating and explaining what can happen and how you can feel; 4) developing a strategy that can be applied in similar situations.
Study: NCT05914454

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anakinra 100Mg/0.67Ml Inj Syringe
Description: anakinra 100 mg per day for 14 days
Study: NCT05754632

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blood Flow Restriction using Delfi Personalized Tourniquet System
Description: The Delfi Tourniquet System is designed to be used in conjunction with exercise. The system automatically determines the degree of occlusion and allows for safe regulation of pressure. Patients will then complete exercises with the use of this device.
Study: NCT04713709

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nasus Pharma FMXIN001
Description: A nasal spray of 4mg Naloxone Hydrochloride powder in a unit dose device

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Nasus Pharma FMXIN001
Description: A nasal spray of 4mg Naloxone Hydrochloride powder in a unit dose device

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nasal Naloxone liquid spray
Description: A nasal spray of 4mg/0.1mL Naloxone Hydrochloride solution in a unit dose device

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Nasal Naloxone liquid spray
Description: A nasal spray of 4mg/0.1mL Naloxone Hydrochloride solution in a unit dose device
Study: NCT06000709

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6% aqueous phenol
Description: 1.5 mL of aqueous phenol will be injected at each target genicular nerve under ultrasound guidance

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MethylPREDNISolone 40 MG
Description: 40 mg of methylprednisolone diluted in 5 mL of 0.9% normal saline will be injected inside the knee joint capsule under ultrasound guidance

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraarticular Knee Placebo
Description: Single injection 1.5 mL of 0.9% normal saline outside the knee joint capsule under ultrasound guidance

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Genicular Nerve Placebo
Description: 1.5 mL of 0.9% normal saline will be injected subcutaneously at each target genicular nerve under ultrasound guidance
Study: NCT05343143

Intervention type: DEVICE
Group type: OTHER
Intervention: NeuraGen 3D Nerve Guide Matrix
Description: Integra NeuraGen 3D Nerve Guide Matrix is a resorbable implant for the repair of peripheral nerve gaps.
Study: NCT06031857

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesio tape
Description: kinesio tape was applied over the specific muscle of rotator cuff

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dry needling
Description: dry needling was applied over the affected muscles
Study: NCT04718545

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mucogingival surgery
Description: The gingival recession at mandibular incisor site will be covered by a gingival graft harvested from the palate.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mucogingival surgery
Description: The gingival recession at mandibular incisor site will be covered by a gingival graft harvested from the palate.
Study: NCT04418921

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional self-regulation program
Description: The children from control group will follow a program of emotional education of Primary Schools, though group activities in the classroom .The content of the sessions will include 5 sessions of emotional awareness and 5 sessions of emotional and cognitive regulation.Each session will last 50 minutes
Study: NCT06255873

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: L- Carnitine
Description: L-carnitine was taken after feeds in the form of tablets or dissolved tablets in a dose of 50 mg/kg/day, with maximum dose of 2 g/day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ketogenic diet
Description: ketogenic diet (KD) initiated under supervision of expert physician who considered patient's age, type of feeding, needs and preferences of the child and his/her family to select the type and initial ratio of KD therapy, KD ratio ranged from 1:1 to 4:1 of lipids to carbohydrates plus proteins in grams.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ketogenic diet
Description: ketogenic diet (KD) initiated under supervision of expert physician who considered patient's age, type of feeding, needs and preferences of the child and his/her family to select the type and initial ratio of KD therapy, KD ratio ranged from 1:1 to 4:1 of lipids to carbohydrates plus proteins in grams.
Study: NCT05941104

Intervention type: OTHER
Intervention: frailty
Description: Frailty is a group of common clinical syndromes in the elderly, characterized by systematic, dynamic and reversible, the core of which is the decline of physiological reserves and the destruction of self-balance.
Study: NCT05522426

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SyntrFuge System
Description: Microsized Adipose Tissue
Study: NCT06292871

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Additional GDM management through social media
Description: Usual care provided by a diabetes nurse educator and dietitian. Additional educational resources for dietary management care received, and for any queries to be addressed by dietitian via social media platform from baseline to one-month follow-up visit.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual care provided by a diabetes nurse educator and dietitian.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care provided by a diabetes nurse educator and dietitian.
Study: NCT05827796

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IN10018
Description: IN10018 orally once daily at approximately the same time each day, to ensure a dosing interval of approximately 24 hours.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IN10018
Description: IN10018 orally once daily at approximately the same time each day, to ensure a dosing interval of approximately 24 hours.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin-Bound Paclitaxel
Description: Albumin-bound paclitaxel will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin-Bound Paclitaxel
Description: Albumin-bound paclitaxel will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN046
Description: KN046 5 mg/kg on Day 1 of each 21-Day Cycle.
Study: NCT06134297

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cycle ergometer
Description: The Aerobic Exercise Group will perform a cycle ergometer for 15 consecutive minutes with a load adjusted to maintain heart rate (HR) between 65-75% of the maximum HR predicted for age (HRmax = 200-age). Peripheral oxygen saturation will be controlled and, upon a sustained drop (\> 2 minutes after load reduction) below 90%, the session will be interrupted. The subjective feeling of tiredness in the legs and shortness of breath will be constantly monitored and if values equal to or greater than 8 (0-10) occur, the exercise will be stopped.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Strength Training - elastic band and shin guards
Description: The Anaerobic Exercise Group will perform muscular strength training using maximum strength, where the contraction time should not exceed 20 seconds. For the upper limbs, the overload used will be through the use of an elastic band, with guidance for the patient to perform the shoulder external rotation exercise, elbow flexion exercises and open row rowing exercise. For the lower limbs, bridge movements, lunges and sit-up exercises will be performed with a maximum of 15 repetitions, and overload with ankle weights or dumbbells can be used in addition to body weight. The muscle contraction should lead the patient to a state of muscular fatigue and if the objective is not achieved, the exercise will be adapted to require greater strength from the patient so that he or she can reach maximum strength.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cycle ergometer, elastic band and shin guards
Description: Mixed Exercise Group will perform the exercises by alternating between aerobic and anaerobic overload, in a 1:1 ratio until the end of the physical rehabilitation program, following exactly the same protocols described previously (alternating one session of the aerobic protocol and in the following session the anaerobic protocol).
Study: NCT05585255

Intervention type: DIAGNOSTIC_TEST
Intervention: enzyme-linked immunosorbent assay(ELISA)
Description: After allowing to stand at room temperature for 2h, blood samples are centrifuged at 4 ℃ for 15 min (12000 rpm) to collect the supernatant. Then, the levels of DKK2, IL-6, IL-1β, TNF-α, and IL-10 in the supernatants are tested by ELISA detection.
Study: NCT06299943

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biofeedback gait training by biomechanical target parameter
Description: The patient walks using a treadmill at a comfortable speed until he gets tired. The patient is instructed that when performing a virtual task (in a virtual environment on the screen), his walking will be harmonized (without informing him on what parameter). If it fails to cope, then the zones of permissible changes (on the information columns) will expand, and the virtual task will signal its incomplete completion.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biofeedback gait training by biomechanical target parameter
Description: The patient walks using a treadmill at a comfortable speed until he gets tired. The patient is instructed that when performing a virtual task (in a virtual environment on the screen), his walking will be harmonized (without informing him on what parameter). If it fails to cope, then the zones of permissible changes (on the information columns) will expand, and the virtual task will signal its incomplete completion.
Study: NCT05491759

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Product 1 - AquaCelle Fish Oil Triglyceride
Description: 1 dose of 2 capsules equivalent to 1.6g Fish Oil Triglyceride (standardised to contain 1120 mg of eicosapentaenoic acid and docosahexaenoic acid (EPA+DHA)) and 0.4g AquaCelle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Product 2 - AquaCelle Fish Oil Ethyl Ester
Description: 1 dose of 2 capsules equivalent to 1.6g Fish Oil Ethyl Ester (standardised to contain 1120 mg of eicosapentaenoic acid and docosahexaenoic acid (EPA+DHA)) and 0.28g AquaCelle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Product 3 - Standard Fish Oil Triglyceride
Description: 1 dose of 2 capsules equivalent to 1.6g Fish Oil Triglyceride (standardised to contain 1120 mg of eicosapentaenoic acid and docosahexaenoic acid (EPA+DHA)).
Study: NCT05168670

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Protection of eyes with tinted soft scleral eye shields
Description: In subjects with dry eye disease due to meibomian gland dysfunction, protection of eyes with tinted soft scleral eye shields followed by IPL administration on eyelids
Study: NCT05026671

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endotracheal Tube Alone
Description: Intubating the trachea with an endotracheal tube alone ( without stylet).
Study: NCT04695873

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Corn Foam Cushion
Description: An anatomically shaped foam pad with a central hole. The upper layer is made from a honeycomb of interconnecting cells, the external facing surface is smooth, the underside is coated with adhesive.
Study: NCT04488458

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MIC or MBEC+MIC based treatment algorithm
Description: i) Non cell wall active standard of care antibiotic combination (MIC-guided) for 6 weeks.~ii) Non cell wall active antibiotic combination according to a MBEC-based decision algorithm for 6 weeks.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MIC or MBEC+MIC based treatment algorithm
Description: i) Non cell wall active standard of care antibiotic combination (MIC-guided) for 6 weeks.~ii) Non cell wall active antibiotic combination according to a MBEC-based decision algorithm for 6 weeks.
Study: NCT06042673

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pomegranate seed oil
Description: 10 g of pomegranate seed oil+40g mixed oil (palm oil/ rapeseed oil/ safflower oil (4:0.5:0.5)) will be added to the test meal for breakfast

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Mixed vegetable oil
Description: 50g mixed oil (palm oil/ rapeseed oil/ safflower oil (4:0.5:0.5)) will be added to the test meal for breakfast
Study: NCT05026671

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Tube+ Stylet
Description: Intubating the trachea with an endotracheal tube + stylet.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Tube + Video-laryngoscope
Description: Intubating the trachea with an endotracheal tube + Video- laryngoscope

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal tube + stylet with Video-laryngoscope
Description: Intubating the trachea with an endotracheal tube + stylet + Video-laryngoscope
Study: NCT05050448

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sustained Acoustic Device with 2.5% Diclofenac Patch
Description: Patients apply the SAM Ultrasonic Diathermy Device daily for 1-4 hours of continuous therapeutic ultrasound at 3 megahertz(MHz) frequency and 0.132 Watts/cm@ with 2.5% Diclofenac patches.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sustained Acoustic Device with 2.5% Diclofenac Patch
Description: Patients apply the SAM Ultrasonic Diathermy Device daily for 1-4 hours of continuous therapeutic ultrasound at 3 megahertz(MHz) frequency and 0.132 Watts/cm@ with 2.5% Diclofenac patches.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 1% Diclofenac Topical Gel
Description: Topical pain-relief gel
Study: NCT04448106

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Celltex- AdMSCs
Description: Autologous adipose-derived stem cells Culture expanded mesenchymal stem cells isolated from a patient's own abdominal fat tissue

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Celltex- AdMSCs
Description: Autologous adipose-derived stem cells Culture expanded mesenchymal stem cells isolated from a patient's own abdominal fat tissue

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Celltex- AdMSCs
Description: Autologous adipose-derived stem cells Culture expanded mesenchymal stem cells isolated from a patient's own abdominal fat tissue

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Celltex- AdMSCs
Description: Autologous adipose-derived stem cells Culture expanded mesenchymal stem cells isolated from a patient's own abdominal fat tissue

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Celltex- AdMSCs
Description: Autologous adipose-derived stem cells Culture expanded mesenchymal stem cells isolated from a patient's own abdominal fat tissue

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Celltex- AdMSCs
Description: Autologous adipose-derived stem cells Culture expanded mesenchymal stem cells isolated from a patient's own abdominal fat tissue
Study: NCT06370507

Intervention type: DEVICE
Intervention: Electrical impedance tomography assessment of ventilation distribution in course of sedation/general anesthesia for pediatric surgery
Description: Assessment of ventilation distribution through electrical impedance tomography in pediatric patients subjected to sedation or general anesthesia for surgery
Study: NCT04865952

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: periodontal surgery + 24 hr buccal attached gingiva (G) biopsy
Description: Periodontal surgery will be performed and 24 hr after the surgical procedure a 2mm punch biopsy will be harvested at the level of the buccal attache gingiva (G).

Intervention type: PROCEDURE
Group type: OTHER
Intervention: periodontal surgery + 24 hr buccal attached gingiva (G) biopsy
Description: Periodontal surgery will be performed and 24 hr after the surgical procedure a 2mm punch biopsy will be harvested at the level of the buccal attache gingiva (G).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HA application
Description: HA will be applied at the end of the surgical procedure, at the level of the vertical released incisions (VRIs) and over VRIs
Study: NCT05879471

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 68Ga-NY104 PET/CT
Description: Participants will be administered a single, intravenous bolus of 68Ga-NY104 The recommended administered activity of 68Ga-NY104 is 1.8-2.2 MBq per kilogram bodyweight, subject to variation that may be required owing to variable elution efficiencies obtained during the lifetime of the 68Ga / 68Ga generator The CT and PET imaging session will begin approximately 45 to 75 minutes after 68Ga-NY104 administration.
Study: NCT05481840

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continence material with sensor
Description: Healthcare organizations are prepared for the use of smart continence care (for the intervention condition) using specially developed implementation guideline. They receive training, including how to apply continence material (only provided to intervention condition).~Each participating location will use the product for 12 weeks. Correct size and absorption level will be determined for each participant. The optimize the result, this can change. Evaluation meetings with the caregivers, supplier and researcher will be held. Resulting in suggestions for alterations in continence care provided or products used, or giving indications that a team needs support in any way to foster the implementation.~After 12 weeks, the implementation guidance from the research group will be phased out.~The waiting list group will continue their continence care as usual during data collection period. Thereafter they will receive support for implementing smart continence care.
Study: NCT05638971

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ivWatch
Description: The second half sample size PIVC will be enrolled into an alarming group. ivWatch will monitor the PIVC insertion site collecting data and sending visual and auditory notifications of any infiltration. The goals of the study on the alarming group are: a) to estimate the notification rate (the number of detected infiltration in the studied period; b) to evaluate the extension and severity of the detected infiltration at the time of the notification, so to gather if ivWatch is helpful in early diagnosis