TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05988944

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TT+CIMT+VR
Description: TT: Traditional Techniques CIMT: constraint-induced movement therapy VR: virtual reality

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TT+CIMT
Description: TT: Traditional Techniques CIMT: constraint-induced movement therapy

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TT
Description: TT: Traditional Techniques
Study: NCT04836169

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: InCaveo's EOA system with integrated mobile CBT
Description: integrated pain management therapeutic and tapering system including a software apt that manages and tracks patient-reported outcomes, including pain levels, medication use, quality of life
Study: NCT05796492

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pulsed splenic ultrasound
Description: A General Electric LOGIQ E10 ultrasound machine with a C1-6-XD clear probe, will be used to selectively deliver pulsed ultrasound to the spleen.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Ultrasound probe (no energy applied)
Description: A General Electric LOGIQ E10 ultrasound probe will be placed over the spleen with no energy applied
Study: NCT05022459

Intervention type: DRUG
Intervention: Emicizumab
Description: Patients in this group will be on standard of care Emicizumab prophylaxis for Hemophilia A

Intervention type: DRUG
Intervention: FVIII
Description: Patients in this group will be on standard of care FVIII prophylaxis for Hemophilia A
Study: NCT05495932

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: blood sample
Description: blood sample taken to measure serum mepolizumab concentration at baseline, 1 month and 6 months during study follow-up
Study: NCT05144321

Intervention type: OTHER
Intervention: Impact of environment upon obstetrical
Description: Impact of environment upon obstetrical

Intervention type: OTHER
Intervention: neonatal and maternal adverse outcome
Description: neonatal and maternal adverse outcome
Study: NCT06003075

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Post Induction XRT
Description: Induction Chemo-NIVO x 3 cycles then CT and biopsy, followed by concurrent Chemo and Nivo XRT (60Gy). Participants will receive concurrent thoracic radiation therapy using a standardized 3DCRT or IMRT technique on a linear accelerator operating at 2:6 MV beam energy. The target total dose of thoracic radiation therapy will be 60 Gy in 30 daily fractions of 2 Gy prescribed to the PTV. The participants then will receive NIVO at 480 mg IV every 4 weeks for 12 cycles.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Post Induction XRT
Description: Induction Chemo-NIVO x 3 cycles then CT and biopsy, followed by concurrent Chemo and Nivo XRT (60Gy). Participants will receive concurrent thoracic radiation therapy using a standardized 3DCRT or IMRT technique on a linear accelerator operating at 2:6 MV beam energy. The target total dose of thoracic radiation therapy will be 60 Gy in 30 daily fractions of 2 Gy prescribed to the PTV. The participants then will receive NIVO at 480 mg IV every 4 weeks for 12 cycles.
Study: NCT06304480

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 100g fermented Tofu
Description: * Participants will consume 100 g Miso fermented tofu per day which may be consumed any way i.e. fried, grilled, baked, etc to taste or prepared from the list of recipes provided.~* Participants will consume the first Study Product on the day of their Visit 3 (Day 0) and will consume their last Study Product the day prior to Visit 5 (Day 56).~* Participants will be instructed to return any unused Study Product at Visit 5 (Day 56).
Study: NCT05463588

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercising with virtual reality glasses
Description: GIVE PATIENTS EXERCISE WITH A 360 DEGREE EXERCISE VIDEO INSIDE VIRTUAL REALITY EYES.~Exercising with the training material taught at the beginning of the training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercising with virtual reality glasses
Description: GIVE PATIENTS EXERCISE WITH A 360 DEGREE EXERCISE VIDEO INSIDE VIRTUAL REALITY EYES.~Exercising with the training material taught at the beginning of the training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercising with virtual reality glasses
Description: GIVE PATIENTS EXERCISE WITH A 360 DEGREE EXERCISE VIDEO INSIDE VIRTUAL REALITY EYES.~Exercising with the training material taught at the beginning of the training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercising with virtual reality glasses
Description: GIVE PATIENTS EXERCISE WITH A 360 DEGREE EXERCISE VIDEO INSIDE VIRTUAL REALITY EYES.~Exercising with the training material taught at the beginning of the training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercising with virtual reality glasses
Description: GIVE PATIENTS EXERCISE WITH A 360 DEGREE EXERCISE VIDEO INSIDE VIRTUAL REALITY EYES.~Exercising with the training material taught at the beginning of the training
Study: NCT05514457

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: visual stimulation with I pad
Description: At the beginning of the study, for baseline condition, children will do 4 tests (visuo-spatial perception test, visual attention span, visual research, phonology tests).~In the first group of the study, the children will do visual research exercises on I pad 10 minutes per day during one month = remediation. They will also do 4 reading aloud tests, once a month, for 3 months. The remediation exercises will be realized during the first, second or third month.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: visual stimulation with lamp
Description: At the beginning of the study, for baseline condition, children will do the 4 tests like group 1.~In the second group of the study, the children will do reading aloud tests, with lamp adjusted with different parameters = remediation (passive visual stimulation of a specific frequency believed to promote visual processing of written symbols).
Study: NCT05753735

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Piperacillin/Tazobactam
Description: Piperacillin/Tazobactam 3.375 g IV every 6 hours while inpatient following surgery, not to exceed 10 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Piperacillin/Tazobactam
Description: Piperacillin/Tazobactam 3.375 g IV every 6 hours while inpatient following surgery, not to exceed 10 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin/ Clavulanic acid
Description: Amoxicillin/ Clavulanic acid 875/125 mg every 12 hours after discharge to complete 10 days total antibiotics
Study: NCT06438887

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Corn-Starch Maltodextrin
Study: NCT04583774

Intervention type: OTHER
Group type: OTHER
Intervention: Prediction error tasks
Description: The intervention involves two tasks, one that involves taste stimuli and another that involves monetary stimuli, and test their impact o brain response in electro encephalography (EEG) and functional magnetic resonance imaging (fMRI)
Study: NCT06438887

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Corn-Starch Maltodextrin

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Corn-Starch Maltodextrin
Study: NCT06438887

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Corn-Starch Maltodextrin

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Creatine monohydrate
Description: Creatine

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Creatine monohydrate
Description: Creatine

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Creatine monohydrate
Description: Creatine
Study: NCT04931771

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: vFFR guided revascularization
Description: 3D-angio-based vessel FFR (CAAS, Pie Medical Imaging, Maastricht, The Netherlands) uses 3-Dimensional Quantitative Coronary Angiography (3D-QCA) for functional assessment of coronary stenosis. vFFR is calculated using two angiographic views with at least 30 degrees difference in rotation/angulation to generate the 3D reconstruction of the coronary artery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FFR guided revascularization
Description: Fractional flow reserve (FFR) is a technique used in coronary catheterization to measure pressure differences across a coronary artery stenosis (narrowing, usually due to atherosclerosis) to determine the likelihood that the stenosis impedes oxygen delivery to the heart muscle (myocardial ischemia)
Study: NCT04609020

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: JUVÉDERM
Description: JUVÉDERM VOLBELLA with Lidocaine Treatment of any fine lines and medium-sized skin depressions. Can also be used for enhancement and pouting of the lips to correct structural defects such as asymmetry, contour deformities, volume loss. JUVÉDERM VOLIFT with Lidocaine Intended for the treatment of any deep skin depressions due to conditions such as premature aging. Can also be used for face contouring and volume restoration to correct facial structural defects such as asymmetry, contour deformities, volume loss in the lips, cheeks, chin, lower face. JUVÉDERM VOLUMA with Lidocaine Intended to restore volume of the face JUVÉDERM VOLITE with Lidocaine Intended for treatment, by filling, of superficial cutaneous depressions such as fine lines and for additional improvement of skin quality attributes such as hydration and elasticity. JUVÉDERM VOLUX with Lidocaine Intended to restore and generate facial volume in chin and mandible areas

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BOTOX
Description: Indicated for the treatment of hyperkinetic facial lines.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HArmonyCA Lidocaine
Description: HArmonyCa Lidocaine injectable gel is a dermal filler intended for facial soft tissue augmentation.
Study: NCT04616677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-42847922
Description: JNJ-42847922 tablet will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-42847922
Description: JNJ-42847922 tablet will be administered orally.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JNJ-42847922
Description: JNJ-42847922 tablet will be administered orally.
Study: NCT05297461

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medication review
Description: Community pharmacy benchmarking guideline Pharmaceutical Services Division provides guidelines for medication review in community pharmacy settings in Malaysia
Study: NCT04869982

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RZV
Description: 2 doses of RZV in 0, 2 months schedule, administered intramuscularly in the deltoid region of the non-dominant arm

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 doses of placebo in 0, 2 months schedule, administered intramuscularly in the deltoid region of the non-dominant arm
Study: NCT05830890

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sentinel lymph node biopsy
Description: After the total mesorectal excision, the indocyanine green was injected around the tumor via the anus. The fluorescence laparoscope was used to visualize and locate the sentinel lymph node, which was then removed and sent for rapid frozen pathological examination. Subsequently, a lateral lymph node dissection was performed.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine green solution
Description: Indocyanine green was injected around the tumor via the anus to visualize the sentinel lymph nodes under the fluorescence laparoscope.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: fluorescence laparoscope
Description: The fluorescence laparoscope was used to visualize and locate the sentinel lymph node.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: pathological examination
Description: The surgical specimens and sentinel lymph nodes were routinely examined for pathology.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: rapid frozen pathological examination
Description: The lateral green fluorescence imaging sentinel lymph nodes found during surgery was sent to make cryosections. And then a pathologist makes a rapid diagnosis under a microscope。

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: total mesorectal excision
Description: 1. Sharply dissect the vascular interface between the pelvic fascia parietal layer and the visceral layer around the mesentery under direct vision to ensure that the rectal mesentery of the resected specimen is intact and tearless.~2. For medium and low rectal cancer: the distal intestinal tube of the tumor should be resected ≥ 2 cm.~3. TME or mesenteric distal resection margin ≥ 5 cm away from the tumor.
Study: NCT05649696

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Staphylokinase
Description: Intravenous injection of r-SAK is administered within 10 minutes after diagnosis of acute ST-segment elevation myocardial infarction

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: Intravenous injection of normal saline is administered within 10 minutes after diagnosis of acute ST-segment elevation myocardial infarction
Study: NCT05285059

Intervention type: BEHAVIORAL
Intervention: ASRT task
Description: The ASRT (Alternating Serial Reaction Time) task is a computerized behavioral task measuring implicit learning. This task consists of 20 series of trials lasting 2 minutes each.~In each trial, a stimulus is displayed on the screen in one of the four possible predefined locations. The participant must press a button to indicate the position of the stimulus on the screen. Response content and response time are recorded.~At the end of every trial, the participant can take a break and resume the task whenever ready. The task lasts about 45 to 50 minutes.

Intervention type: BEHAVIORAL
Intervention: ASRT task
Description: The ASRT (Alternating Serial Reaction Time) task is a computerized behavioral task measuring implicit learning. This task consists of 20 series of trials lasting 2 minutes each.~In each trial, a stimulus is displayed on the screen in one of the four possible predefined locations. The participant must press a button to indicate the position of the stimulus on the screen. Response content and response time are recorded.~At the end of every trial, the participant can take a break and resume the task whenever ready. The task lasts about 45 to 50 minutes.
Study: NCT05530655

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lisinopril Tablets
Description: This is a dose escalation study of 5 mg, 10 mg and 20 mg doses given once a day.
Study: NCT06344546

Intervention type: DIAGNOSTIC_TEST
Intervention: Metabolomics
Description: Analysis of the metabolome in plasma samples.

Intervention type: DIAGNOSTIC_TEST
Intervention: Metabolomics
Description: Analysis of the metabolome in plasma samples.
Study: NCT06549738

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent pneumatic compression therapy
Description: Lympha Press Optimal Plus is an advanced intermittent pneumatic compression therapy device. It is FDA cleared (K170658) for the indication of lipedema as well as for other indications for use.
Study: NCT05826340

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tailored progressive loading and return to sport
Description: Participants will undergo a 5-stage progressive return to sport tool.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pain guided activity
Description: Participants will be provided on information on how to guide activity based on pain response.
Study: NCT05644288

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Help eNursing
Description: The proposed intervention is a telephonic telenursing program aimed at managing social isolation in the elderly, the HELPeN (Help eNursing) program.~The operational part of the intervention will be carried out by volunteers nursing students from the University of Murcia enrolled in the academic years 2020-2023. To ensure homogeneity in the intervention carried out by the volunteers they will receive a 15-hour training oriented to ensure the acquisition of essential communication skills for the implementation of the intervention and to know the specific interventions of support and counseling for the elderly in social isolation.~Over the 36 weeks of the HELPeN Program, each volunteer is expected to provide intervention to 2 seniors, making 1 call per week to each subject lasting approximately 30 minutes. Students will perform physical and psychosocial assessments of the elders and create individualized care plans based on each subject's needs.
Study: NCT05225389

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 300 mg [C14] CT1812
Description: Single dose of 300 mg CT1812 with microtracer dose of \[C14\]
Study: NCT05065294

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin therapy
Description: - Psilocybin administration session 10mg-25mg delivered orally with psychological support and monitoring
Study: NCT06156605

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sidelying lumbar manipulation
Description: R sided lumbar manipulation

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sidelying lumbar manipulation
Description: R sided lumbar manipulation
Study: NCT05201677

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
Description: After the capsule is filled with viscoelastic material, if the IOP is less than 10 mmHg, the investigators will supply the perfusion fluid through the subiris suspensory ligament space from the lateral incision.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
Description: After the capsule is filled with viscoelastic material, if the IOP is less than 10 mmHg, the investigators will supply the perfusion fluid through the subiris suspensory ligament space from the lateral incision.
Study: NCT05283265

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sentence Type
Description: Subjects read different types of sentences (object-relative, subject -relative and control sentences) to observe how that sentence affects their intracranially recorded neural activity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Direct brain stimulation
Description: On some trials the investigators will apply intracranial electrical current through the electrodes implanted in the participants and observe the effect this has on their behavior (which picture they choose at the end of the trial) and the effect this has on their neural activity that the investigators record simultaneously through-out the experiment.
Study: NCT04928456

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Treatment (OMT)
Description: Osteopathic Manipulative Treatment (OMT) involves a number of hands-on techniques that are meant to address somatic dysfunction in the body as a part of the osteopathic approach to treating patients. There will be five techniques in total used in the study treatment plan.
Study: NCT05816668

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: Patients with prostate cancer and radical video laparoscopy prostatectomy indication will receive 1,0g of Tranexamic Acid solution IV in bolus 20 minutes before of anesthetic induction, followed by a maintenance hose of 1,0mg/kg/h of surgery.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients randomized to placebo group will receive physiological saline and will undergo to the radical video laparoscopu prostatectomy normally
Study: NCT03228940

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RVX000222
Description: oral, BID
Study: NCT05621772

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Meridian Activation Remedy System for Parkinson's Disease (MARS-PD)
Description: MARS-PD is a complex therapy developed by researchers to enhance the synergistic effects of acupuncture and exercise.
Study: NCT04727593

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Cognitive Therapy (MBCT)
Description: Experimental group: MBCT is program developed by Zindel Segal, Mark Williams, and John Teasdale , based on Jon Kabat-Zinn's Mindfulness-based Stress Reduction (MBSR) program. Participants learn to acknowledge their unhelpful thoughts and feelings, allowing the mind to move from an automatic and spiraling thought pattern to a more conscious emotional processing. Mindfulness practices include breath awareness, sitting and walking meditations, and mindful yoga. In this study, the following MBCT structure will be followed: group setting of 12 participants (maximum); 8 online weekly meetings of 2 hours via a videoconference platform (e.g., Cisco Webex), each one mediated by a trained mindfulness instructor(s); daily home practice of the learned skills; 2 hours of retreat after the fifth week; 6 months of home practice; 4 monthly consolidation sessions of 90 minutes each.

Intervention type: OTHER
Group type: OTHER
Intervention: Treatment as Usual
Description: In this case, participants will follow the usual institutional intervention protocol for medical follow-up and identification, referral, and intervention for people with significant distress difficulties. Regarding pharmacological intervention, medication intake will be monitored during the study and changes will be registered. The engagement in non-pharmacological interventions such as psychological and psychosocial interventions will also be monitored.