TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06382324

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mindfulness practice of body scan
Description: Mindfulness intervention is one kind of psychological intervention. The founder of Mindfulness-Based Stress Reduction (MBSR), Jon Kabat-Zinn, described mindfulness as \&#34;awareness that arises through paying attention, on purpose, in the present moment, non-judgmentally\&#34; (Kabat-Zinn, 2003). Moreover, these attitudes can be nurtured through various practices such as body scan, meditation, yoga, mindful eating, and mindful walking. Mindfulness practices are recognized for their ability to alleviate stress among athletes and enhance their recovery capabilities (Li et al., 2019). Mindfulness practice has been shown to enhance athletes\&#39; performance (Chen et al., 2018)、 improve sleep quality (Rusch et al., 2019)，which in turn promotes emotional stability and physical recovery.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: listening to light music
Description: listening to light music asa control
Study: NCT05463978

Intervention type: DEVICE
Intervention: Sculptra Aesthetic
Description: Sculptra Aesthetic in non-facial areas
Study: NCT06539793

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercises
Description: Treadmill 20 minutes including 5 minutes warm up and 5 minutes cool.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercises
Description: Treadmill 20 minutes including 5 minutes warm up and 5 minutes cool.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical nerve stimulation
Description: will be applied for all patients, which uses an asymmetrical biphasic alternating current in the continuous mode (pulse duration 100 µs, low frequency). TENS intensity will increase slowly, and patients will be instructed to indicate sensory threshold (ST); then, the intensity are going to increase until the sensation perceived as strong but comfortable (SC1). The duration will be for 30 minutes, 3times/ week for 4 weeks
Study: NCT05809999

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard colonoscopy with targeted biopsies
Description: Participants will undergo standard colonoscopy as part of their routine IBD surveillance. During this colonoscopy targeted biopsies (biopsies of any pre-cancerous lesions observed by the doctor) and/or removal of any polyps will be undertaken.
Study: NCT06542679

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Application
Description: A mobile health application based on Social Cognitive Theory (SCT) and the Information-Motivation-Behavioral Skills (IMB) model has been developed. The design of the mobile health application is grounded in SCT, the IMB model, and behavioral change interventions and techniques. The content of the mobile application is based on the 'Healthy Weight Gain Guide for Pregnancy.' The application offers a comprehensive program that provides evidence-based recommendations using self-monitoring, feedback, shaping information, goal setting, planning, and reward techniques for healthy nutrition, physical activity, and optimal gestational weight gain for pregnant women.
Study: NCT04633382

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Enhanced recovery after biliary tract surgery
Description: Patients with malignant and benign diseases of the bile ducts, who have formed various types of anastomosis in two options for managing the postoperative period: traditional and based on the principles of enhanced recovery after surgery

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Enhanced recovery after biliary tract surgery
Description: Patients with malignant and benign diseases of the bile ducts, who have formed various types of anastomosis in two options for managing the postoperative period: traditional and based on the principles of enhanced recovery after surgery
Study: NCT06270914

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Inclusive Positive Behavior Interventions and Supports
Description: The intervention is based on the Norwegian manualized program of SW-PBIS, N-PALS (Positiv Atferd, Støttende Læringsmiljø, og Sammhandling). The Norwegian model shares its core components with the original SW-PBIS model. The program's core components constitute: (a) positive behavior support strategies, including positive expectations and classroom rules, which are followed up with positive feedback and encouragement; (b) a system for monitoring student behavior, (c) school-wide corrections using consequences, (c) instruction in classroom management skills for teachers, and (e) strategies for collaboration with parents. These components are implemented through activities at school level and at classroom level.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Inclusive Positive Behavior Interventions and Supports
Description: The intervention is based on the Norwegian manualized program of SW-PBIS, N-PALS (Positiv Atferd, Støttende Læringsmiljø, og Sammhandling). The Norwegian model shares its core components with the original SW-PBIS model. The program's core components constitute: (a) positive behavior support strategies, including positive expectations and classroom rules, which are followed up with positive feedback and encouragement; (b) a system for monitoring student behavior, (c) school-wide corrections using consequences, (c) instruction in classroom management skills for teachers, and (e) strategies for collaboration with parents. These components are implemented through activities at school level and at classroom level.
Study: NCT04340739

Intervention type: OTHER
Intervention: online patient education teach mindfulness based stress reduction
Description: This is an online self management chronic pain curriculum that presents adapted Mindfulness Based Stress Reduction through videos, audios, and written materials
Study: NCT06421038

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thyme honey
Description: Thyme honey is a rich monofloral honey variety formed by bees that collect nectar from thymus vulgaris flowers. thyme honey application (100% pure natural honey, applied by themselves) on their ulcers three times a day for 7 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Kenalog
Description: kenalog in orabase (Triamcinolone acetonide 0.1% in oral paste 5g)
Study: NCT05330208

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1816
Description: SHR-1816
Study: NCT05240846

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Paramedian conventional palpation group
Description: Patients in this group underwent conventional landmark guided paramedian spinal anesthetic. The spinal anesthesia will be administered based on conventional landmark-based paramedian approach.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound assistance paramedian spinal group
Description: This group will have their spinal anesthetic done based on ultrasound assistance paramedian spinal. Spinal anesthesia with a paramedian approach was performed based on the optimum puncture point, suggested puncture angles, and puncture depth. The suggested puncture angles included the cephalad angle measured by the built-in angle program of the ultrasound and the medial angle measured by a 180° protractor (Deli). The puncture depth, the distance from the skin to the posterior complex, was measured utilizing the ultrasound clipper tool.
Study: NCT06191289

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal Estradiol
Description: 1mg/24hr transdermal estradiol for 14 days starting day 7 after positive urine luteinizing hormone test~Other Names:~Climara

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Weekly application of a placebo patch for 14 days starting day 7 after positive urine luteinizing hormone test
Study: NCT04340739

Intervention type: OTHER
Intervention: online patient education teach mindfulness based stress reduction
Description: This is an online self management chronic pain curriculum that presents adapted Mindfulness Based Stress Reduction through videos, audios, and written materials

Intervention type: OTHER
Intervention: online patient education teach mindfulness based stress reduction
Description: This is an online self management chronic pain curriculum that presents adapted Mindfulness Based Stress Reduction through videos, audios, and written materials
Study: NCT05330208

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06462183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RGT-61159
Description: Oral MYB inhibitor
Study: NCT05955768

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Disposable cervical dilator stick combined with lidocaine hydrochloride injection
Description: The subject will undergo routine disinfection and receive cervical paracervical nerve block anesthesia (5mL of 1% lidocaine injection at the level of the bilateral sacral ligaments). After waiting for 2 minutes, the researcher gently checks the depth of the uterine cavity with a probe and then remove it. The nurse connects the disposable cervical dilator to the syringe containing lidocaine hydrochloride. The researcher inserts the disposable cervical dilator into the cervical canal in line with the probe direction, and slowly inject drug from the syringe into it within a minute. The researcher waits for another minute before removing the disposable cervical dilator. The researcher removes the IUD with a ring hook. If necessary, the researcher will use metal Hegar dilators to dilate cervix.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Disposable cervical dilator stick combined with normal saline injection
Description: The subject will undergo routine disinfection and receive cervical paracervical nerve block anesthesia (5mL of 1% lidocaine injection at the level of the bilateral sacral ligaments). After waiting for 2 minutes, the researcher gently checks the depth of the uterine cavity with a probe and then remove it. The nurse connects the disposable cervical dilator to the syringe containing normal saline. The researcher inserts the disposable cervical dilator into the cervical canal in line with the probe direction, and slowly inject drug from the syringe into it within a minute. The researcher waits for another minute before removing the disposable cervical dilator. The researcher removes the IUD with a ring hook. If necessary, the researcher will use metal Hegar dilators to dilate cervix.
Study: NCT06462183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RGT-61159
Description: Oral MYB inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RGT-61159
Description: Oral MYB inhibitor
Study: NCT05184634

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PHYSICAL ACTIVITY LEVELS
Description: Determination of physical activity levels of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PHYSICAL ACTIVITY LEVELS
Description: Determination of physical activity levels of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: DEPRESSION LEVELS
Description: To determine the depression levels of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: DEPRESSION LEVELS
Description: To determine the depression levels of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: FATİGUE SEVERİTY
Description: To determine the severity of fatigue of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: FATİGUE SEVERİTY
Description: To determine the severity of fatigue of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: QUALITY OF LIFE
Description: To determine the quality of life of MetS individuals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: QUALITY OF LIFE
Description: To determine the quality of life of MetS individuals
Study: NCT05322434

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Effect Of Online Breastfeeding Counseling Given At The Post-Birth Period On Breastfeeding Behavior
Description: The aim of the study is to investigate breastfeeding behavior and initiation of solid food by giving breastfeeding counseling to women within the framework of the Health Belief Model for 6 months from birth.
Study: NCT04765514

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biomarker based treatment (Temozolomide monotherapy or Radiotherapy monotherapy)
Description: Temozolomide or Radiotherapy

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Chemo-Radiotherapy consisting of 40 Gy in 15 daily fractions with concurrent temozolomide.
Description: Temozolomide will be administered at a dose of 75 mg/m2 daily for a total of 21 days. This will be followed by adjuvant temozolomide (150-200 mg/m2 daily for 5 day
Study: NCT05206812

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: durvalumab
Description: * durvalumab 1500 mg QD\*~* Surgery within 1 to 8 weeks - 4 cycles of durvalumab 1500 mg/m2 (Day 1, Day 8)+cisplatin 80 mg/m2 (Day 1) q3wks -durvalumab 1500 mg q4wks (Maximum of 10 cycles)
Study: NCT06019078

Intervention type: DEVICE
Intervention: SedLine
Description: Continuous 4 channel processed neurological monitor
Study: NCT06162780

Intervention type: DIAGNOSTIC_TEST
Intervention: ultrasonic cardiography (UCG)
Description: Trans-thoracic echocardiography (TTE) is performed in the resting position. Trans-esophageal echocardiography (TEE) is performed under surface anaesthesia with bupivacaine or intravenous anaesthesia. We comprehensively assess the severity of mitral regurgitation according to American Society of Echocardiography (ASE) guideline.

Intervention type: PROCEDURE
Intervention: TEER
Description: Two commercial cliping systems are available for clinical use: the G3 MitraclipTM and the G4 MitraclipTM (Abbott), DragonflyTM (Dejin), which will be introduced to the Chinese market in 2024, with the specific choice determined by the operator. The patient receives general anaesthesia (intravenous and endotracheal). The operator performs the procedure according to the recommended surgical steps in the product manual, guided by X-ray and trans-esophageal echocardiography. Postoperative MR ≤2+ is considered successful, and if the result is unsatisfactory, 1-2 additional clips are given.
Study: NCT06450509

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Babble Boot Camp
Description: Caregivers are coached by a pediatric speech-language pathologist to implement activities and routines into their daily home lives with the intent to foster and boost their child's precursor and earliest speech and language skills. The intervention will be conducted entirely via telehealth.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Babble Boot Camp
Description: Caregivers are coached by a pediatric speech-language pathologist to implement activities and routines into their daily home lives with the intent to foster and boost their child's precursor and earliest speech and language skills. The intervention will be conducted entirely via telehealth.
Study: NCT06566651

Intervention type: OTHER
Intervention: Emotion Discrimination Task (EDT)
Description: It estimates the subjective bias and sensitivity in discriminating between happy and angry facial expressions of different intensities of emotional expression
Study: NCT05878535

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Metformin 850 mg oral tablets. Prescribed: Once daily PO with meals and 200 mL of water. The dose can be up-titrated to 1500-2000 mg divided q8-12hr with meals in enrolled diabetic patients as a monotherapy or combined with sulfonylurea.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo oral tablets. Prescribed: Once daily PO with meals and 200 mL of water.
Study: NCT06566651

Intervention type: OTHER
Intervention: Emotion Discrimination Task (EDT)
Description: It estimates the subjective bias and sensitivity in discriminating between happy and angry facial expressions of different intensities of emotional expression

Intervention type: OTHER
Intervention: Emotion Discrimination Task (EDT)
Description: It estimates the subjective bias and sensitivity in discriminating between happy and angry facial expressions of different intensities of emotional expression
Study: NCT06455475

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Derm-Maxx
Description: Derm-Maxx™ Dermal Matrix is an acellular human dermis graft sterilized using the Tutoplast® Tissue Sterilization Process.
Study: NCT06568757

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wet Cupping
Description: Wet cupping therapy will be applied once using disposable plastic vacuum cups to a total of 4 areas, which are recommended areas for headaches; cervical spine C7 (DU14 acupuncture point), bilateral T2-4 lateral spine (BL41-42 acupuncture point) and suboccipital region (FengFu DU-16 acupuncture point).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No intervention
Description: No treatment will be applied to individuals and the routine medical treatment program will continue.
Study: NCT06454955

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga] B7H3 Affibody-BCH
Description: An affibody structure specifically targeting B7H3 was developed based on the B7H3 binding domain, and it was structurally optimized to yield a small molecular agent, B7H3 Affibody-BCH, suitable for nuclear medical diagnostic and therapeutic uses targeting B7H3. By labeling with the radioactive isotope \^68Ga, this agent can be used for PET/CT diagnosis of solid tumors.
Study: NCT04957316

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Triple-effect blood purification filter
Description: Blood purification using the oXiris filter to remove endotoxin, cytokines, and uremic toxins.
Study: NCT05471141

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognition ECHO
Description: Cognition ECHO is the intervention designed to be used by the study participants who are primary care practitioners. No involvement of patients in this study. The panel will consist of the CI and Co-PIs of this study, a neurologist as a co-moderator, a medical specialist who is the expert on the subject, an occupational therapist, a psychologist, and a speech and language pathologist with experience and expertise in CI. A patient with CI and a caregiver, family member, or community representative who is not a healthcare professional will join the panel because CI is frequently observed with lived experience of family members and loved ones, as two non-clinician panelists. The five topics with the integration of related diagnoses for Cognition ECHO are listed in Table 4. The time allocated for the didactic will be 15-20 minutes and the de-identified case discussion will be 40 - 45 minutes.
Study: NCT05716516

Intervention type: DRUG
Group type: OTHER
Intervention: Estradiol
Description: Estradiol is a therapeutic option for the treatment of advanced ER+ breast cancer
Study: NCT05514327

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: ultra-fraction radiotherapy
Description: the R/R DLBCL patients would receive ultra-fraction radiotherapy as bridging therapy before the CD19 CART cell infusion
Study: NCT06122623

Intervention type: OTHER
Group type: OTHER
Intervention: Health Education
Description: As previously mentioned, the intervention for this study will be a gaming education program that will be conducted once with each participant. Implementation of the program will occur at different times. Each performance will include a maximum of 60 participants who will be divided into small groups within the same room. Seven to 10 participants will comprise a small group, and each group will have one facilitator. The facilitator will be either a member of the research team or a Health lecturer who will be recruited and trained by the Japanese and Indonesian research teams.
Study: NCT06402058

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DMSB01
Description: Apply a maximum of 1.0 ml for each side of the Crow's Feet Lines using both the test device (DMSB01) and the control device (Rejuran®).
Study: NCT03881748

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual acupuncture
Description: Manual acupuncture twice a week for 20 treatments.~Acupuncture will be administered on an outpatient basis in private rooms with participants lying supine. The acupuncturist will disinfect the selected acupuncture points with alcohol and then needle them so that the participant achieves a de qi sensation if possible, which is often described as a pressure or achiness feeling. Acupuncture needles will be left in place for approximately 20 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electro-acupuncture
Description: Electro-acupuncture twice a week for 20 treatments.~Acupuncture will be administered on an outpatient basis in private rooms with participants lying supine. The acupuncturist will disinfect the selected acupuncture points with alcohol and then needle them so that the participant achieves a de qi sensation if possible, which is often described as a pressure or achiness feeling. Acupuncture needles will be left in place for approximately 20 minutes.~Electrical stimulation will be applied to the needles concomitantly and continuously to acupuncture points by placing lead wires on the needles connected to an electro-acupuncture stimulator such as the Model IC-1107. The stimulator will be set on the Dense-Disperse wave setting with low frequency at 2-10 Hz and high frequency at 100-110 Hz. The needles will not be manually stimulated after electrical stimulation is applied.
Study: NCT05847621

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer recovery coaching with linkage to recovery resources
Description: Peer recovery coach (PRC) assessment of the participant's state of change, engage in motivational interviewing techniques, and link the participant to community-based recovery resources according to the needs of the participant. They will also schedule and perform follow up calls after the participant is discharged from the ED to provide ongoing support and facilitate re-linkage to recovery resources, if needed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer recovery coaching with linkage to recovery resources
Description: Peer recovery coach (PRC) assessment of the participant's state of change, engage in motivational interviewing techniques, and link the participant to community-based recovery resources according to the needs of the participant. They will also schedule and perform follow up calls after the participant is discharged from the ED to provide ongoing support and facilitate re-linkage to recovery resources, if needed.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants will be provided with a list of community recovery resources.