TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05435196

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic exercise
Description: The control group and the experimental group will receive the training with high-intensity interval exercise. For a period of 12 weeks both groups will participate in their exercise program, which will be supervised by the physiotherapist in charge of the study; different from the one who will carry out the randomization and the one who will perform the evaluations. Women will attend 3 times a week for an hour to the Hospital de especialidades to receive their exercise program in which they participated. Both groups will receive therapeutic education to encourage adherence and self-management, which include aspects such as flexibility, musculoskeletal pain, physical performance, quality of life focused on physical and mental health, etc.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic exercise
Description: The control group and the experimental group will receive the training with high-intensity interval exercise. For a period of 12 weeks both groups will participate in their exercise program, which will be supervised by the physiotherapist in charge of the study; different from the one who will carry out the randomization and the one who will perform the evaluations. Women will attend 3 times a week for an hour to the Hospital de especialidades to receive their exercise program in which they participated. Both groups will receive therapeutic education to encourage adherence and self-management, which include aspects such as flexibility, musculoskeletal pain, physical performance, quality of life focused on physical and mental health, etc.
Study: NCT03442491

Intervention type: PROCEDURE
Intervention: Hayman's Haemostatic Suture
Description: After the uterus is exteriorised, bimanual compression is applied to check whether this stopped the bleeding, before the suture is applied. A number 2 polyglactin suture on a straight needle is used to transfix the uterus from front to back, just above the reflection of the bladder, and is then tied above the fundus of the uterus, while an assistant applies bimanual compression.
Study: NCT05373615

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cefiderocol
Description: After receipt of Cefiderocol, blood samples will be collected at various time points to determine the pharmacokinetics of Cefiderocol
Study: NCT05910164

Intervention type: DEVICE
Intervention: PELGRAZ prefilled syringe or PELGRAZ prefilled pen
Description: PELGRAZ prefilled syringe or PELGRAZ prefilled pen https://www.ema.europa.eu/en/medicines/human/EPAR/pelgraz

Intervention type: DEVICE
Intervention: PELGRAZ prefilled syringe or PELGRAZ prefilled pen
Description: PELGRAZ prefilled syringe or PELGRAZ prefilled pen https://www.ema.europa.eu/en/medicines/human/EPAR/pelgraz
Study: NCT05946031

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reat ETM
Description: Exclusive cigarette smokers will be recruited and will be exposed to the real ETM condition in which tobacco purchases are real and they receive products from one randomly selected trial.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reat ETM
Description: Exclusive cigarette smokers will be recruited and will be exposed to the real ETM condition in which tobacco purchases are real and they receive products from one randomly selected trial.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hypothetical ETM
Description: Exclusive cigarette smokers will be recruited and will be exposed to the hypothetical ETM condition in which tobacco purchases are hypothetical and they don't receive any products.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hypothetical ETM
Description: Exclusive cigarette smokers will be recruited and will be exposed to the hypothetical ETM condition in which tobacco purchases are hypothetical and they don't receive any products.
Study: NCT05041075

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Weighted Blanket
Description: Weighted blankets provide Deep Pressure Stimulation (DPS) or Deep Touch Pressure (DTP) which has advantages in both physical and psychological domains.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Weighted Blanket
Description: Weighted blankets provide Deep Pressure Stimulation (DPS) or Deep Touch Pressure (DTP) which has advantages in both physical and psychological domains.
Study: NCT06561594

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: recombinant human follicle-stimulating hormone-CTP Fusion protein injection
Description: IF Weight \> 60kg，150ug, H. Administer the drug once every 14 days for 64 weeks；IF Weight \>≤60kg，100ug, H. Administer the drug once every 14 days for 64 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: recombinant human follicle-stimulating hormone-CTP Fusion protein injection Placebo
Description: 0.5ml, H. Administer the drug once every 14 days for 64 weeks
Study: NCT05025085

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN1777
Description: An immunoglobulin gamma (IgG1) antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN1777
Description: An immunoglobulin gamma (IgG1) antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: a PD-1 inhibitor
Description: Anti-programmed cell death protein 1 (Anti-PD-1) antibody monoclonal antibody
Study: NCT05502679

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Weight bearing as tolerated
Description: Bearing weight on lower limb extremity

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pragmatic Exercise protocol
Description: Designed exercise prescriptions according to the patients' needs

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pragmatic Exercise protocol
Description: Designed exercise prescriptions according to the patients' needs
Study: NCT04660864

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nasal cavity cooling device.
Description: The RhinoChill® system cools by intranasal evaporation of a liquid coolant sprayed onto the surface of the nasal cavity. The RhinoChill® system is intended for use for the relief of pain and symptoms associated with acute migraine attack.
Study: NCT06395324

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High arabinose diet
Description: Participants will consume a high arabinose diet for 18 consecutive days.
Study: NCT05905276

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ERAS Protocol
Description: The ERAS protocol for ambulatory TURBT has been designed based on patient and provider input, a needs assessment of 150 patients in the hours after TURBT, a review of the literature, and experience with other ambulatory ERAS protocols already implemented at Johns Hopkins Hospital. The ERAS protocol for ambulatory TURBT aims to optimize care delivered in the pre, intra and postoperative settings.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Patients in the usual care arm of the EMBRACE trial will experience the present-day care pathway of ambulatory TURBT at Johns Hopkins Hospital.
Study: NCT06656286

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intra-Uterine suturing by X-TACK device and hysteroscope
Description: After general anesthesia and entering the abdomen with the laparoscope, Truclear hysteroscope with X-tack attached will be inserted to the uterine cavity. Insertion of normal saline to the cavity and applying 4 points suturing to the uterus. The procedure will be monitored by external laparoscopic camera located in the abdominal cavity. After the hysterectomy the uterus will be opened and the suture will be examine.~A preoperative intrauterine incision using a hysteroscope, followed by suturing, will be considered based on the success of the first procedure.
Study: NCT06656949

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: injecting indocyanine green (ICG) dye Intraoperative
Description: injecting indocyanine green (ICG) dye Intraoperative for patients with endometrial cancer

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: injecting indocyanine green (ICG) dye Intraoperative
Description: injecting indocyanine green (ICG) dye Intraoperative for patients with endometrial cancer
Study: NCT06658002

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine A
Description: Participants with smear or culture proven fungal keratitis are treated for a minimum of 48 hours with topical natamycin and then randomized in a 1:1:1 ratio to receive either topical Cyclosporine A (CsA) 0.1%, 2% or placebo for 4 weeks. Natamycin is continued until the ulcer has healed.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine A
Description: Participants with smear or culture proven fungal keratitis are treated for a minimum of 48 hours with topical natamycin and then randomized in a 1:1:1 ratio to receive either topical Cyclosporine A (CsA) 0.1%, 2% or placebo for 4 weeks. Natamycin is continued until the ulcer has healed.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: Placebo
Description: Participants with smear or culture proven fungal keratitis are treated for a minimum of 48 hours with topical natamycin and then randomized in a 1:1:1 ratio to receive either topical Cyclosporine A (CsA) 0.1%, 2% or placebo for 4 weeks. Natamycin is continued until the ulcer has healed.
Study: NCT06658808

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promoting Community Conversations About Research to End Suicide
Description: Promoting Community Conversations About Research to End Suicide (PC CARES) trains local community health workers to facilitate a series of five 3-hour Learning Circles (LCs) over \~6 months to develop a 'community of practice' (CoP), whereby trusted adults of youth (a) learn about SPBPs; (b) tailor the SPBPs to their culture and community; (c) build cross-sector relationships (parents, teachers, etc.), and (d) do more to prevent suicide. Each session shares evidence-based, actionable ways to enhance social support, reduce harm/risk, and promote help seeking, which participants adapt and apply in their daily interactions with youth.
Study: NCT06587568

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile chat messaging
Description: A trained counsellor will interact with a participant individually and provide personalised alcohol reduction information and advice via a mobile instant messaging app in real time for 3 months from randomisation.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Screening, brief intervention and referral to treatment
Description: Brief counselling (5 to 10 mins) to reduce drinking and a self-help booklet

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Screening, brief intervention and referral to treatment
Description: Brief counselling (5 to 10 mins) to reduce drinking and a self-help booklet
Study: NCT06602024

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1010
Description: Intramuscular (IM) injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Fluarix®
Description: IM injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Influsplit®
Description: IM injection
Study: NCT06672250

Intervention type: OTHER
Intervention: CTCs/CTMs culture
Description: Collect the thrombosis from participants underwent catheter-based thrombectomy.To characterized by cancer-specific surface markers successfully and identify within the culture

Intervention type: OTHER
Intervention: CTCs/CTMs culture
Description: Collect the thrombosis from participants underwent catheter-based thrombectomy.To characterized by cancer-specific surface markers successfully and identify within the culture
Study: NCT06737471

Intervention type: OTHER
Intervention: Intensive rehabilitation treatment
Description: A 3-hour daily rehabilitation treatment will be delivered to each patient 5 days a week for 5 weeks (45 hours) in the care units of the Hospital.~Rehabilitation will address the following macro goals: gross motor, manipulative, visual and visual-cognitive.
Study: NCT06315881

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection
Study: NCT05464563

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electroencephalogram
Description: An electroencephalogram is recorded during a task of rest then self-compassion and then empathy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electroencephalogram
Description: An electroencephalogram is recorded during a task of rest then self-compassion and then empathy.
Study: NCT05979597

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Suprainguinal fascia iliaca block
Description: After the operation is completed, the fascia iliaca will be separated from the iliacus muscle. With ultrasound guidance, the local anesthetic injection will be made between the fascia and the muscle.
Study: NCT04707872

Intervention type: DIAGNOSTIC_TEST
Intervention: MMDx diagnostic test
Description: Microarray test of gene expression in heart biopsies

Intervention type: DIAGNOSTIC_TEST
Intervention: Prospera
Description: Donor derived cell-free DNA in patient blood

Intervention type: DIAGNOSTIC_TEST
Intervention: HLA antibody
Description: Centralized measurement of HLA antibodies in patient blood
Study: NCT06166771

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alma system
Description: Subjects diagnosed with postpartum hemorrhage will receive the Alma System. This system comprises a soft silicone cylindrical device placed within the uterus. Gentle suction is applied, prompting the uterus to contract and reduce in size. This contraction compresses the blood vessels, halting the bleeding.
Study: NCT05858411

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SRP+rhPDGF
Description: The infrabony defect will be debrided with the use of fine ultrasonic tips and mini hand instruments and will be treated with the application of a collagen sponge soaked in rhPDGF.
Study: NCT04617873

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bilateral STN-DBS and T10-T12 SCS
Description: simultaneous stimulation of bilaterally-STN-DBS combined with spinal cord stimulation
Study: NCT04652596

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Produce prescription program
Description: A monthly $150 stipend will be provided to participants for 6 consecutive months to purchase fresh food items at mobile markets and independent farmers markets across Boston.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Grocery store gift cards
Description: A monthly value of $150 in grocery store gift cards redeemable at conventional grocery stores will be provided to participants for 6 consecutive months.
Study: NCT05858411

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SRP+collagen sponge
Description: The infrabony defect will only be debrided with the use of fine ultrasound tips and mini hand instruments and will be treated with the application of a collagen sponge soaked in saline solution.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SRP alone
Description: The infrabony defect will only be debrided with the use of fine ultrasound tips and mini hand instruments and no further treatment will be performed.
Study: NCT06512402

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: patients will receive norepinephrine infusion at rate of 0.05 mcg/Kg/min

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine
Description: patients will receive epinephrine infusion dose of 0.03 mcg/Kg/min
Study: NCT06453694

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Efgartigimod Alfa
Description: 2,016 mg will be administered subcutaneously by a healthcare provider on Day 0 and Day 3 of the trial.~Rescue therapy with therapeutic plasma exchange will be given to any participant based on the results of Day 7 evaluation.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subcutaneous injection of placebo will be administered by a healthcare provider on Day 0 and Day 3 of the trial.~Rescue therapy with therapeutic plasma exchange will be given to any participant based on the results of Day 7 evaluation.
Study: NCT06374810

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conscious Connected Breathwork
Description: Participants were taught the Conscious Connected Breathwork Technique. 2 facilitators were monitoring and coaching the participants to ensure adherence to the technique

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo waitlist
Description: Participants were told the study was full and that they were placed on a waiting list until the 1st cohort had completed the breathwork program
Study: NCT04939493

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rhythmic Auditory Cueing
Description: Patients will perform the same movement sequence in time with the metronome beat. The frequency of the rhythmic auditory stimulation will be matched to the participants preferred movement speed, which will be assessed prior to the start of the trial, and participants typically started moving after they had heard the metronome beat two to three times. Participants will be given sufficient practice trials to ensure full understanding before the actual recording of data, and will be given 3-minutes break between trials.~On the 3rd and 5th week, the rhythm frequency was increased by 5%.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bilateral arm training
Description: Training will consist of 20 minutes of bilateral arm training In each session, patients will be seated comfortably at a table in the following limb positions: ankles in neutral dorsiflexion, knees and hips placed at 90°, shoulders in 0° flexion, elbows in 60° flexion, and wrists in neutral position of flexion/extension

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bilateral arm training
Description: Training will consist of 20 minutes of bilateral arm training In each session, patients will be seated comfortably at a table in the following limb positions: ankles in neutral dorsiflexion, knees and hips placed at 90°, shoulders in 0° flexion, elbows in 60° flexion, and wrists in neutral position of flexion/extension

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy program
Description: Scapular mobilization. Thoracic spine mobilization. Mechanical assisted (active and passive) exercises. Therapeutic positioning as weight bearing on the paretic arm. Opening and closing closed fist. Strengthening exercise. Stretching of spastic muscles.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physical therapy program
Description: Scapular mobilization. Thoracic spine mobilization. Mechanical assisted (active and passive) exercises. Therapeutic positioning as weight bearing on the paretic arm. Opening and closing closed fist. Strengthening exercise. Stretching of spastic muscles.
Study: NCT05446675

Intervention type: PROCEDURE
Intervention: Endoscopic eTEP
Description: Endoscopic extended view totally extraperitoneal prosthesis repair.

Intervention type: PROCEDURE
Intervention: Open Rives-Stoppa
Description: Open Rives-Stoppa repair with retromuscular mesh placement.
Study: NCT05979597

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Suprainguinal fascia iliaca block+dexamethasone
Description: After the operation is completed, the fascia iliaca will be separated from the iliacus muscle. With ultrasound guidance, the local anesthetic+dexamethasone injection will be made between the fascia and the muscle.
Study: NCT06423027

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nature-Oriented Chatbots
Description: Nature-oriented chatbots are an intervention with nature-based video delivered by self-developed chatbots
Study: NCT05528276

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Repair surgery
Description: 1. a circumscribing skin incision was made 2 mm below the hypospadias meatus,~2. penile degloving,~3. the para-urethral plate incision was made,~4. A vertical midline incision of the urethral plate was made from within the hypospadiac meatus and extended up to the mid-glans.~5. The urethral plate was tubularised, beginning proximally, and closed in two layers using 6/0 polyglactin 910 suture.~6. The neomeatus was formed on a catheter 2 F larger than the urethral stent.~7. A flap was harvested from the prepuce to cover the neourethra and finally glanuloplasty.~8. A suitable urethral stent was left in situ for 7-10 days, with a compressive dressing applied.~   * Grafted tubularised incised-plate .~1.Same steps but adding a graft (dorsal inlay) , 2. The graft will be taken from the inner preputial skin . 3. The graft will be sutured to overlying plate incision line from the old meatus to the tip of the glans.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Repair surgery
Description: 1. a circumscribing skin incision was made 2 mm below the hypospadias meatus,~2. penile degloving,~3. the para-urethral plate incision was made,~4. A vertical midline incision of the urethral plate was made from within the hypospadiac meatus and extended up to the mid-glans.~5. The urethral plate was tubularised, beginning proximally, and closed in two layers using 6/0 polyglactin 910 suture.~6. The neomeatus was formed on a catheter 2 F larger than the urethral stent.~7. A flap was harvested from the prepuce to cover the neourethra and finally glanuloplasty.~8. A suitable urethral stent was left in situ for 7-10 days, with a compressive dressing applied.~   * Grafted tubularised incised-plate .~1.Same steps but adding a graft (dorsal inlay) , 2. The graft will be taken from the inner preputial skin . 3. The graft will be sutured to overlying plate incision line from the old meatus to the tip of the glans.
Study: NCT05442931

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pregabalin 150mg
Description: The oral tablet half an hour preoperative 150 milligrams

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium Sulfate
Description: Intravenous administration half an hour preoperative 2 grams

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitroglycerin
Description: measure total dose of nitroglycerine in milligrams using a syringe pump

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: surgeon satisfaction
Description: surgeon satisfaction measured according to Likert's scale