TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04867642

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB0022
Description: Study participants will receive doses of UCB0022 in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB0022
Description: Study participants will receive doses of UCB0022 in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB0022
Description: Study participants will receive doses of UCB0022 in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB0022
Description: Study participants will receive doses of UCB0022 in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Study participants will receive placebo comparator in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Study participants will receive placebo comparator in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study participants will receive placebo comparator in a pre-specified sequence during the Treatment Period of Part A, B and C.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study participants will receive placebo comparator in a pre-specified sequence during the Treatment Period of Part A, B and C.
Study: NCT05253573

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine patch
Description: Provision of nicotine replacement medications in the form of transdermal patches is important to address nicotine withdrawal/craving for smokers who want to quit. Evidence supporting the safety and efficacy of NRT is vast. The PHS Guideline indicates that use of NRT doubles quit rates and should be considered the minimal standard care. Therefore, we will provide NRT to all participants in both groups in the early cessation phase.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine patch
Description: Provision of nicotine replacement medications in the form of transdermal patches is important to address nicotine withdrawal/craving for smokers who want to quit. Evidence supporting the safety and efficacy of NRT is vast. The PHS Guideline indicates that use of NRT doubles quit rates and should be considered the minimal standard care. Therefore, we will provide NRT to all participants in both groups in the early cessation phase.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-help materials (to support smoking cessation)
Description: Our team has translated and validated the World Health Organization's A guide for tobacco users to quit into Lao language for use as the self-help material in this study.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-help materials (to support smoking cessation)
Description: Our team has translated and validated the World Health Organization's A guide for tobacco users to quit into Lao language for use as the self-help material in this study.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone-based automated treatment for smoking cessation
Description: The automated treatment(AT) include text messages, images, and videos. The AT content is designed to tap the theoretical mechanisms described in the Phase-Based Model (PBM). That is, treatment content is designed to increase motivation, self-efficacy, use of coping skills, and social support, while reducing nicotine withdrawal symptoms and stress. The AT will begin immediately after enrollment and continue for a 12-week period. The AT approach allows for several levels of personalization for each participant, including tailoring to participants' specific health conditions, individual cessation phases, and participants' self-efficacy level or smoking status in the past week.
Study: NCT04901247

Intervention type: BEHAVIORAL
Intervention: media refreshment
Description: 20µL of culture medium is aspirated using Eppendorf PCR tips, and freshly, overnight equilibrated 20µL global total LP will be added to the same well

Intervention type: BEHAVIORAL
Intervention: media refreshment
Description: 20µL of culture medium is aspirated using Eppendorf PCR tips, and freshly, overnight equilibrated 20µL global total LP will be added to the same well

Intervention type: BEHAVIORAL
Intervention: embryo grading
Description: embryo grading should be done prior to media refreshment

Intervention type: BEHAVIORAL
Intervention: embryo grading
Description: embryo grading should be done prior to media refreshment
Study: NCT06473896

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketalar
Description: a dissociative anesthetic used medically for induction and maintenance of anesthesia

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: an agonist of α2-adrenergic receptors in certain parts of the brain used for sedation
Study: NCT05394246

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FluoAB
Description: Drug Injection: FluoAB (fluorescent-labeled IgG)
Study: NCT05387369

Intervention type: DRUG
Intervention: Paxlovid
Description: The study is a real-world study. According to the actual medical history of patients, the usage of paxlovid will be collected.
Study: NCT04781283

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: measurement of endothelial cell density by specular microscopy
Description: During this first appointment (T0), in addition to the usual treatment, measurement of the endothelial cell density by specular microscopy will be carried out on the affected eye (basal cell density). To overcome the variability linked to the machine, three consecutive measurements will be taken; the average of the three measurements will be used.~As part of his post-operative follow-up, the patient will be reviewed at one month, one year, two years, three years, four years and five years after the operation. During these consultations and as part of the research, a new determination of the cell density (3 consecutive measurements) by specular microscopy of the operated eye and an evaluation of the position of the XEN implant will be carried out each time. ® by OCT scan for patients having undergone this surgery.
Study: NCT05080075

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet Rich Plasma Injection
Description: Research participants own blood will be used to prepare the platelet rich plasma injectate, which will be injected into the affected knee using ultrasound guidance.
Study: NCT06021431

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MORE-VR
Description: An 8-session version of Mindfulness-Oriented Recovery Enhancement (MORE) delivered by virtual reality. The treatment involves training in mindfulness,reappraisal, and savoring techniques to address OUD.~Combination Product: Participants in this arm will also receive Treatment as usual (TAU) with medications for opioid use disorder (MOUD). Usual addictions treatment with medications such as buprenorphine or methadone plus psychological counseling.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as Usual
Description: Participants will receive their usual treatment for OUD, including medications such as buprenorphine or methadone and any counseling they might already be receiving

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual
Description: Participants will receive their usual treatment for OUD, including medications such as buprenorphine or methadone and any counseling they might already be receiving
Study: NCT05443880

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The exercise intervention will focus on working the core muscles, starting with low-intensity isometric contraction of the core muscles that stabilize the trunk; increasing intensity by performing functional tasks (phase 1: independent isometric contraction of transversus-abdominis and multifidus, phase 2: co-contraction and functional tasks of the deep trunk muscles; phase 3: functional task with load; phase 4: functional task with unstable surface)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise + mindfulness
Description: The Mindfulness Based Stress Reduction (MBSR) program will strictly follow the protocol developed by Jon Kabat Zinn. Each session will include three activities: the presentation of a topic, moments of dialogue and exploration in group (using appreciative inquiry) and a Mindfulness practice. Participants will be provided with workbooks, audios with guided meditations, and instructions for practice at home. In addition, the Exercise + mindfulness intervention will include the exercise program described in the exercise intervention.

Intervention type: OTHER
Group type: OTHER
Intervention: Control group
Description: The control group will be provided with the usual care received in the Physical Medicine and Rehabilitation Service: stretching, breathing and motor control exercises 2 days / week (45 minutes per session) during a period of 8 weeks.
Study: NCT05334953

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ESWT
Description: Group 1 (n = 17) will be given two times a week, total 5 sessions of ESWT + home exercise program~Other: Home Workout Program Patients will be given eccentric exercises and stretching exercises

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Phonophoresis
Description: Group 2 ( n=17) will be given five times a week total 10 sessions of diclofenac phonophoresis + home exercise program~Other: Home Workout Program Patients will be given eccentric exercises and stretching exercises

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound
Description: Group 3 (n=17) will be given five times a week total 10 sessions of ultrasound therapy+ home exercise program~Other: Home Workout Program Patients will be given eccentric exercises and stretching exercises

Intervention type: OTHER
Group type: OTHER
Intervention: Control group
Description: Other: Home Workout Program Patients will be given eccentric exercises and stretching exercises
Study: NCT05746533

Intervention type: PROCEDURE
Intervention: Hip Arthroscopy
Description: Hip Preservation surgeries
Study: NCT05478681

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active tDCS
Description: All participants will receive active tDCS with a constant current intensity of 2mA. Anodal tDCS will be applied to the left dorsolateral prefrontal cortex, while cathodal electrode will be positioned on the right dorsolateral prefrontal cortex. Caregivers will help setting up and administering tDCS for participants with AD at home. tDCS will be applied for 30min at an intensity of 2mA, with 30 s ramping up and down.
Study: NCT05645458

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mobile application ( PEG Assist )
Description: The mobile application is used for PEG care. İt gives some information to caregivers related to PEG, PEG care, etc. Also, the researcher can monitor all feeding times with this application.
Study: NCT04727697

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augmented Reality
Description: Patients will receive the preoperative AR experience during their immediately preoperative office visit. The duration of the exposure is approximately 15 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care preoperative teaching and handouts
Description: At preoperative appointments, patients receive verbal teaching and written handouts about day of surgery instructions and expectations.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care preoperative teaching and handouts
Description: At preoperative appointments, patients receive verbal teaching and written handouts about day of surgery instructions and expectations.
Study: NCT05980247

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thimble Application
Description: Use of of thimble application to practice mindfulness before needle procedure.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thimble Application
Description: Use of of thimble application to practice mindfulness before needle procedure.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thimble Application
Description: Use of of thimble application to practice mindfulness before needle procedure.
Study: NCT04891263

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suture-Septoplasty
Description: Patients receive suture-septoplasty for repair of nasal septal deviation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical suture
Description: Suture used for closure during septoplasty surgery.
Study: NCT06645587

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active HD-tDCS over pre-SMA
Description: Active cathodal HD-tDCS over pre-SMA cortex will be delivered for 10 days (3 sessions per week). The 4 × 1 montage using small circular electrodes (diameter 1 cm) will be applied with the cathode placed centrally over Fz. The current intensity will be set at 0.5 mA for a total of 20 minutes (30 s ramp up/down).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active HD-tDCS over left DLPFC
Description: Active cathodal HD-tDCS over left DLPFC cortex will be delivered for 10 days (3 sessions per week). The 4 × 1 montage using small circular electrodes (diameter 1 cm) will be applied with the cathode placed centrally over F3. The current intensity will be set at 0.5 mA for a total of 20 minutes (30 s ramp up/down).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham HD-tDCS
Description: Sham HD-tDCS will be delivered over pre-SMA or left-dlPFC cortex for 10 days (3 sessions per week). The same electrodes placement as well as the stimulation set-up will be used as in the active stimulation conditions, but the current will be applied for 30 s and will be ramped down (0 mA) during the rest of the session without the participants awareness. Each Sham session will last 20 minutes.
Study: NCT05104957

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamic tape
Description: The experimental group will use a special dynamic patch made of cotton, coated with a hypoallergenic acrylic heat-activated adhesive arranged in sinusoidal-shaped layers. The tape will be applied using the muscle technique with a Y-shaped cut patch directly to the dried and non-greased skin. The application will be performed in a standing position, with the participant's lower extremities straight. The therapist will place the beginning of the tape (the base) on the participant's sacrum and then, asking them to bend 45 degrees forward, tape the tails of the tape along the spine on the extensor muscles of the lumbar region, without changing the tension of the tape, keeping the base in the initial position.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham tape
Description: In the control group, a plain paper patch will be used to conduct the study, which, like the dynamic patch, will be applied using the same form of tape cutting and the same application technique. The entire method of applying the patch will also take place in the participant's standing position with forward bending. The paper patch will be placed at the levels from the L3 segment to the sacrum, along the spine on the lumbar extensor muscles.
Study: NCT06645561

Intervention type: PROCEDURE
Intervention: X-ray
Description: defined radiographic semiological criteria to determine an analytical methodology to facilitate the dating of long bone fractures of infants under one year of age
Study: NCT05680415

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mycobacterium Vaccae for Injection
Description: The experimental group was alternately injected with 1 dose of microcard every two weeks (0-2-4-6-8-10 weeks) in the left and right hip muscle deep, and a total of 6 doses were injected.
Study: NCT06472882

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS targeting DLPFC
Description: The anodic electrode will be placed on the left DLPFC (area F3) and the cathode on the right orbitofrontal cortex (area Fp2). Participants will receive 20 minutes of tDCS at 2 mA while seated.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS targeting M1
Description: The anodes will be placed over C3 and C4 (according to EEG 10-20 system), and the cathodes over the ipsilateral shoulders. Participants will receive 20 minutes of tDCS at 2 mA while seated.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SHAM tDCS
Description: The electrodes will be placed as in the other conditions, but the stimulation will be switched off after 30 seconds, providing an initial stinging sensation without continuous stimulation.
Study: NCT06266065

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Coronary Sinus Reducer
Description: Implantation of Coronary Sinus Reducer
Study: NCT05888558

Intervention type: DEVICE
Intervention: Body fluid diagnosis
Description: miRNAs derived from exosomes in the serum

Intervention type: DEVICE
Intervention: Body fluid diagnosis
Description: miRNAs derived from exosomes in the serum

Intervention type: DEVICE
Intervention: Body fluid diagnosis
Description: miRNAs derived from exosomes in the serum
Study: NCT05278910

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Soybean oil + Roasted wheat flour
Description: Assign soybean oil capsule and roasted wheat flour
Study: NCT04390971

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ET-01
Description: Recruited participants will receive ET-01 IV infusion after conditioning.
Study: NCT05278910

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fish oil + Roasted wheat flour
Description: Assign fish oil and roasted wheat flour

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Soybean oil + Vegetable and fruit extracts
Description: Assign soybean oil and vegetable and fruit extracts

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fish oil + Vegetable and fruit extracts
Description: Assign fish oil and vegetable and fruit extracts
Study: NCT06225765

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transoral endoscopic thyroidectomy vestibular approach (TOETVA)
Description: Remote access thyroid surgery

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Open Thyroidectomy
Description: Open thyroidectomy via trans-cervical approach
Study: NCT05668117

Intervention type: DEVICE
Intervention: Depuy Synthes Advanced Retrograde femoral nail
Description: The Advanced Retrograde Femoral Nailing System (RFNA) is designed to improve fixation and stabilization of distal femur and femoral shaft fractures by reducing toggle and loss of reduction.
Study: NCT05042479

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual distraction and pain prevention techniques.
Description: For the first painful procedure, the child will benefit usual distraction and pain prevention techniques.Pain prevention and management techniques commonly used in the conduct of care:~* Application of a patch or anaesthetic cream 1 hour before the treatment~* Vigilant sedation using a premedication for lumbar punctures: Midazolam /Nalbuphine/Hydroxyzine/Morphine.~* Apart from care using VR, MEOPA can be given to the child for all assessed care on prescription.~* Apart from care using VR, the usual distraction techniques are left to the patient's choice (electronic tablet, smartphone, games, songs...)~* The presence of the parents

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: For the 2nd painful procedure, the child will use a VR (virtual reality) headset as well as pain prevention techniques (excluding oxygen-nitrous oxide mixtures). The child will choose the application he/she wishes to use according to his/her age.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Choice between usual distraction or virtual reality
Description: For the 3rd painful procedure, the child will choose his/her favorite technique between :~Usual distraction and pain prevention techniques or virtual reality
Study: NCT05183971

Intervention type: OTHER
Intervention: Proprioceptive Functional Analysis System
Description: Proprioceptive testing and Physical Performance Tests

Intervention type: OTHER
Intervention: Proprioceptive Functional Analysis System
Description: Proprioceptive testing and Physical Performance Tests
Study: NCT05214833

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Real Neurofeedback
Description: During neurofeedback, the brain activity in response to a motor task is recorded in real-time and displayed back to the participants.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham Neurofeedback
Description: During sham neurofeedback, a signal which resembles the participant's brain activity is used instead of the actual brain activity.
Study: NCT06224738

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: human HER2-targeted CAR-M cells
Description: The human anti-HER2 chimeric antigen receptor macrophages (anti-HER2 CAR-M cells) independently developed use adenoviral vector system to genetically engineer autologous macrophages to express CAR molecules containing single-chain antibodies, which specifically bind to the human HER2 antigen to recognize and kill tumor cells.
Study: NCT05514353

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PBI-100 Topical Cream
Description: PBI-100 Topical Cream in 1 of 3 dose levels

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: The Vehicle Cream formulation contains the same excipients as the active cream
Study: NCT05885672

Intervention type: BEHAVIORAL
Intervention: Online psychoeducational lifestyle intervention
Description: A webpage-baed intervention focused on lifestyle interventions that aim to reduce metabolic syndrome severity.
Study: NCT06095570

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciprofol
Description: For induction of anesthesia, an experimental dose of ciprofol was given, and when the patient lost consciousness and the Modified Observer's Alertness/Sedation scale(MOAA/S score) was less than 1, then intravenous sufentanil and rocuronium bromide were administered, and tracheal intubation was performed 3 minutes later

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remimazolam
Description: For induction of anesthesia, an experimental dose of remimazolam was given, and when the patient lost consciousness and the Modified Observer's Alertness/Sedation scale(MOAA/S score) was less than 1, then intravenous sufentanil and rocuronium bromide were administered, and tracheal intubation was performed 3 minutes later
Study: NCT06580665

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryoablation
Description: Patients undergo cryoablation.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryoablation
Description: Patients undergo cryoablation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Serplulimab
Description: Patients undergo cryoablation. If there are no significant postoperative complications, Serplulimab should be administered immediately. Cycles with Serplulimab repeat every 3 weeks for up to 1 year in the absence of disease progression or unacceptable toxicity.