TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05804500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cardiac Telerehabilitation (CTR) via the RecoveryPlus platform
Description: RecoveryPlus has developed an innovative CTR platform for patients with CVD that leverages: (1) video conferencing functionality (Zoom) for synchronous telehealth sessions of CR instruction for patients and licensed exercise physiologists (EPs), (2) a patient-facing mobile application delivering asynchronous exercise videos, and (3) a health care provider web portal for clinicians and EPs. The RecoveryPlus platform includes the ability for EPs and clinicians to monitor patient clinical data (e.g., heart rate) and input (e.g., rating of difficulty for individual exercises) and tailor individual patient regimens regularly for increased safety and optimal outcomes.
Study: NCT05433090

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Inpatient serious illness care program
Description: Inpatient advance care planning intervention that will be delivered by advanced care practitioners or hematology/oncology fellow physicians. The intervention will be an adapted version of the serious illness care program.
Study: NCT05211375

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Duodenojejunal bypass
Description: Sleeve gastrectomy will be performed in the same manner as in the SG group. DJB will be performed by transection of the duodenum and bypassing 250 cm of the proximal jejunum. The handsewn suture will be used for duodenojejunal anastomosis, and the size of anastomosis will be 1.5 - 2 cm. Single anastomosis will be performed rather than Roux-en-Y fashion.
Study: NCT05345522

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 4mg/kg
Description: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 4mg/kg, intravenous injection for 60 to 90 minutes. Every 2 weeks is a cycle, the first day of each cycle is administered, a total of ≥ 4 cycles.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 6mg/kg
Description: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 6mg/kg, intravenous injection for 60 to 90 minutes. Every 2 weeks is a cycle, the first day of each cycle is administered, a total of ≥ 4 cycles.
Study: NCT05211375

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sleeve gastrectomy
Description: Sleeve gastrectomy will be performed using 36-38 Fr bougie. The initial stapling start point will be between 4-6 cm from the pylorus, and the last stapling will be performed at least 1 cm away from His angle. The height of the automatic stapler will be selected based on the researcher's discretion.
Study: NCT05345522

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 8mg/kg
Description: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 8mg/kg, intravenous injection for 60 to 90 minutes. Every 2 weeks is a cycle, the first day of each cycle is administered, a total of ≥ 4 cycles.
Study: NCT05028010

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Capacity building
Description: Four days of training on the promotion of maternal and child nutrition will be given. The training will be based on Pender's health promotion model. Supportive supervision will be conducted.
Study: NCT04667468

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cold Stored Platelets (CSP)
Description: early infusion of urgent release CSP

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care
Description: standard care including blood and blood component therapy
Study: NCT05606874

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional resin fissure sealant
Description: The occlusal fissures will be etched with a 37% phosphoric acid gel for 30 s. After rinsing the enamel with water for 30 s the enamel will be dried for 15 s with compressed air. After completing the fissure preparations a single coat of adhesive (3M ESPE ADPER ,USA) will be applied to the etched surface ,dried under gentle air flow for 2- 3 s and light cured for 20 s using a LED light curing unit with a 1000 mw output .Conventional resin fissure sealant (total etch), (UltraSeal XT®, Ultradent, USA) will be applied to the etched pits and fissures. After removing the rubber dam the occlusion will be checked the sealant will be adjusted with a composite finishing bur and polished with polishing points.
Study: NCT05545163

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: I-gel with standard insertion technique
Description: Standard I-gel insertion technique (grasping I-gel from integral bite block site and cuff facing towards chin and pressing down the manikin chin. I-gel introduced in patient's mouth in a direction towards hard palate. Then I-gel slided downwards and backwards along hard palate with a continuous but gentle push until a definitive resistance is felt)~Modified jaw thrust technique (grasping I-gel from integral bite block site and cuff facing towards chin and pressing down manikin chin. I-gel introduced in patient's mouth in a direction towards hard palate with gently advancing into oropharynx. Then after, I-gel left in oral cavity and both hands used to thrust jaw by lifting angle of mandible with little fingers and other fingers to stabilise jaw. And, at this point, both hand's thumbs used to apply balance force from I-gel stem head towards final placement position by looking at integral bite block mark at incisor teeth level)
Study: NCT05292677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Steroid/Anesthesia Mixture
Description: Steroid will be Triamcinolone Acetonide (40mg/mL). Anesthetic will be 0.5% bupivacaine with 1:100,000 epinephrine. These will be pre-mixed by a qualified personnel within the ENT department.
Study: NCT05805774

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Distal Femur Replacement
Description: Knee surgery to remove the lower part of the femur and knee joint (where the broken bones are) and will replace them with an artificial knee joint (prosthesis).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical fixation
Description: Knee surgery to fix the fracture, that can use wires, nails, screws, pins or plates to health and fix the bones together.
Study: NCT05292677

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 mL of Normal Saline
Study: NCT04918173

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atenativ
Description: Antithrombin concentrate
Study: NCT05149755

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT)
Description: Patients will have a Transcatheter Aortic Valve Replacement (TAVR) with either an Evolut PRO+ TAVR, or Evolut FX TAVR, heart valve, and given clinical site-determined guideline-directed management and therapy (GDMT).
Study: NCT06559501

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integrated case manager care
Description: comprises 8 sessions delivered by case managers. Case managers will provide up to 6 low-intensity sessions in the hospital or the community (if the patient is discharged before completing the required sessions), with content and duration tailored to patient preferences. Post-discharge, patients will receive 2 follow-up sessions with case managers to ensure a smooth transition into the community.
Study: NCT06459752

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: visceral manipulation and noble technique
Description: First, the patient will lie face-up on a massage or exam table. Physiotherapists feel viscera, major internal organs located in the abdomen by lightly pressing through abdominal muscles. Physiotherapist manual poking, pressing, and massage actions do three things:~1. Reveals visceral adhesions.~2. Find tender spots.~3. Breaks up adhesions. Massaging and pressing stretch the collagen fibers that makeup fascia, which loosens tightly bound fibers to break up adhesions. This releases the organs and allows them to move more freely.~Minor adhesions may resolve after one session. Tough, stubborn adhesions may require several sessions plus self-manipulation between sessions

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: noble technique
Description: The patient is positioned in supine with both knees bent and feet flat on a firm surface. The patient then places her crossed hands over her abdomen to support and pull the rectus abdominis muscles towards the midline. Finally, the patient is asked to slowly raise her head until a slight contraction is felt in the abdomen, holding for 20 seconds and repeating the exercise up to 20 times a day
Study: NCT06511661

Intervention type: PROCEDURE
Intervention: Complete lymphadenectomy
Description: At least 3 N1 stations and 3 N2 stations are examined during surgery, including station 7.

Intervention type: PROCEDURE
Intervention: Incomplete lymphadenectomy
Description: Less than 3 N1 stations or 3 N2 stations are examined during surgery, or those without station 7 lymph node dissection.
Study: NCT05088317

Intervention type: DIAGNOSTIC_TEST
Intervention: Exercise capacity
Description: The incremental shuttle walking test at increasing speed (ISWT) is one of the field tests used to evaluate exercise capacity. It has been shown that ISWT is a valid and reliable assessment tool that can be used to evaluate exercise capacity in obese individuals. This test is an exercise test in which walking between two cones 10 m apart at increasing speed for 12 minutes is counted as one sit-up for each 10-meter walk between the two cones. It is continued until the patient is unable to continue the test due to shortness of breath, the heart rate reaches 85% of the maximum expected heart rate, or completes the 12-minute test. In this test, the primary measure is the distance walked, and the result is calculated based on the number of shuttles completed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Exercise capacity
Description: The incremental shuttle walking test at increasing speed (ISWT) is one of the field tests used to evaluate exercise capacity. It has been shown that ISWT is a valid and reliable assessment tool that can be used to evaluate exercise capacity in obese individuals. This test is an exercise test in which walking between two cones 10 m apart at increasing speed for 12 minutes is counted as one sit-up for each 10-meter walk between the two cones. It is continued until the patient is unable to continue the test due to shortness of breath, the heart rate reaches 85% of the maximum expected heart rate, or completes the 12-minute test. In this test, the primary measure is the distance walked, and the result is calculated based on the number of shuttles completed.
Study: NCT05329792

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L19IL2/L19TNF
Description: Patients will be treated with a mixture of L19IL2 and L19TNF once weekly for 4 consecutive weeks
Study: NCT04177498

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rigosertib Sodium
Description: given PO or 72 hour continuous infusion

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT06118879

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous electrical stimulation
Description: sensory level stimulation, one-leg standing and Y-balance training

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical stimulation
Description: sensory level stimulation, one-leg standing and Y-balance training

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous electrical stimulation
Description: sensory level stimulation, one-leg standing and Y-balance training
Study: NCT05907915

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low level laser therapy
Description: They recieved LLLT 1 session daily, 3 session per week for 3 weeks,with the following parameters( 650 nm wavelength, 150 mw power output, 0.25 cm2 radiation area, 0.6 W/cm2 power density, continuous mode, 2 j/ cm2, 90 seconds / cm2) in addition to the conventional medical treatment and traditional wound care (dressing)

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: They received placebo laser 1 session daily, 3 session per week for 3 weeks in addition to the conventional medical treatment and traditional wound care (dressing)
Study: NCT04752787

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online breastfeeding training
Description: Online breastfeeding training will be provided to pregnant women expecting twin babies.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: QR code supported online breastfeeding training
Description: QR code supported online breastfeeding training will be given to pregnant women who are expecting twin babies.
Study: NCT04389138

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy Intervention
Description: Physiotherapy intervention will include an assessment to identify individual areas that physiotherapy should target. Intervention will be based on the core areas recommended by the European Physiotherapy Guideline for Parkinson's Disease: physical capacity (muscle power, tone, joint range of movement, exercise tolerance and pain), transfers, manual dexterity, balance and gait. Posture is incorporated as part of these 5 core areas. The intervention will be delivered over 4 visits.
Study: NCT04631718

Intervention type: RADIATION
Intervention: Magnetic Resonance Imaging (MRI)-based Quantitative Susceptibility Mapping (QSM)
Description: MRI-based QSM methods estimate the susceptibility of tissues based on measuring the magnetic field distortion produced by the tissues themselves.~Upon successful validation, MRI-based abdominal QSM will provide accurate, repeatable, and reproducible quantification of Liver iron concentration (LIC) that is independent of the distribution of iron and does not require calibration.
Study: NCT05332262

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of platelet reactivity
Description: Assessment of platelet reactivity and HPR status will be performed post-PCI. Platelet reactivity will be measured by VerifyNow P2Y12 and HPR status will be defined using a cut-off value of platelet reactivity units (PRU)\>208.

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of platelet reactivity
Description: Assessment of platelet reactivity and HPR status will be performed post-PCI. Platelet reactivity will be measured by VerifyNow P2Y12 and HPR status will be defined using a cut-off value of platelet reactivity units (PRU)\>208.

Intervention type: DIAGNOSTIC_TEST
Intervention: Troponin measurement
Description: Measurement of high sensitivity troponin for the assessment for the presence of myocardial infarction/myocardial injury will be performed post-PCI.

Intervention type: DIAGNOSTIC_TEST
Intervention: Troponin measurement
Description: Measurement of high sensitivity troponin for the assessment for the presence of myocardial infarction/myocardial injury will be performed post-PCI.
Study: NCT05957211

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.09% cyclosporine A ophthalmic solution
Description: Cequa is an ophthalmic solution used to treat moderate to severe dry eye disease. The typical dosage is one drop in each eye, twice a day. The drug is packaged in sterile, single use bottles.
Study: NCT05377840

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy
Description: CBT is a combined psycho-social intervention that aims to improve overall mental health focusing on developing coping strategies. standard CBT Participants will have individual weekly sessions lasting 60 minutes each over an 8-week period with 1 follow-up maintenance session at week 12.
Study: NCT05991479

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercises
Description: Pilates exercises:~The subjects will receive Pilates training (3 sessions/week) for 8 weeks. The Pilates training protocol will take 60 min per session, including 10 min of warm up prior to initiating the Pilates technique, 40 min for Pilates exercises and 10 min for cool down. The number of repetitions will be 10 times. The patient will perform the following Pilates exercises: (Hundred exercises, spine stretch, single leg stretch , double leg stretch, criss cross, swimming, one leg kick, side kick, clam, one leg circle, shoulder bridge, hip twist, roll up and down and standing footwork).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physical therapy programme:
Description: All patients will receive a traditional physical therapy programme consisting of 45 minutes per session of a supervised and individualized exercise programme for three sessions per week for eight weeks which will include:~Stretching exercises for calf and hamstring muscles. Strengthening exercises for hip, knee, ankle, and foot muscles. Deep friction massage for scar management.
Study: NCT04936932

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 1064 nm long-pulse Nd:YAG laser
Description: BCC lesion will be treated with long-pulse 1064 laser

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 1064 nm long-pulse Nd:YAG laser
Description: BCC lesion will be treated with long-pulse 1064 laser
Study: NCT05377840

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sudarshan Kriya Yoga
Description: SKY Breath Meditation is a deep breathing and meditation technique that enables physiological changes leading to improved mental and physical health. Participants will first attend a 3-day online workshop (2.5 hours each day) delivered live by a certified instructor to learn the SKY Breath Meditation practice. Participants will then practice SKY 25 minutes daily for 6 weeks and 3-4 times per week up to 12 weeks.
Study: NCT05991479

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physical therapy programme:
Description: All patients will receive a traditional physical therapy programme consisting of 45 minutes per session of a supervised and individualized exercise programme for three sessions per week for eight weeks which will include:~Stretching exercises for calf and hamstring muscles. Strengthening exercises for hip, knee, ankle, and foot muscles. Deep friction massage for scar management.
Study: NCT00960817

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Statin, aspirin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dipyridamole
Study: NCT05434338

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: HPV detection test
Description: Samples taken from the squamocolumnar junction using swabs (UTM Copan)
Study: NCT05034679

Intervention type: BIOLOGICAL
Intervention: Vcinated
Description: Patients who were vacinated.
Study: NCT04575129

Intervention type: OTHER
Intervention: No intervention will be applied
Description: No intervention will be applied
Study: NCT05413694

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telephone interview 24 months after hospitalization for Covid-19
Description: telephone interview 24 months after hospitalization for Covid-19
Study: NCT06006533

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: taping
Description: Kinesio taping will be applied in accordance with the fascia correction technique, including the plantar flexor muscles, and it will be requested to stay on the skin for 3 days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: massage
Description: Percussive Massage will be applied to the posterior part of the sural fascia, including the plantar flexor muscles, 3 times a week for 5 minutes.
Study: NCT06486077

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Power Line Program
Description: Power Line program consisting of 4 nutritional supplements: a meal replacement shake, a vegetable based green drink, a vascular health product, and a pre-meal fiber supplement
Study: NCT05481450

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutritears®
Description: Strength: Lutein/Zeaxanthin - 20/4 mg; Curcuminoids 200 mg; Vitamin D3 600 IU (Total capsule weight ≈670 mg)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Soybean oil capsule (Total capsule weight ≈670 mg)
Study: NCT05374356

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intrathecal bupivacaine and morphine
Description: Spinal group: will receive high spinal anesthesia with hyperbaric bupivacaine (0.3 to 0.6 mgs/kg) + preservative free morphine (3 mcg/kg).
Study: NCT06225752

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Probucol
Description: Inclusion Days 1-30: Probucol 1000mg/day (500mg per dose, twice daily, a minimum of 4 hours should elapse between each pair of doses.) Inclusion Days 31 and beyond: Probucol 500mg/day (250mg per dose, twice daily, a minimum of 4 hours should elapse between each pair of doses.)
Study: NCT05402410

Intervention type: DIAGNOSTIC_TEST
Intervention: Hepatic venous pressure gradient
Description: All patients underwent measurement of HVPG under local anesthesia.

Intervention type: DIAGNOSTIC_TEST
Intervention: Hepatic venous pressure gradient
Description: All patients underwent measurement of HVPG under local anesthesia.
Study: NCT05923619

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Total pulpotomy
Description: Total pulpotomy procedures explained in arm descriptions.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Root canal treatment
Description: Root canal treatment procedures explained in arm descriptions.
Study: NCT05745194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promotion of adherence to the MedDiet
Description: Participants will be followed in six individual nutrition consultations with a duration of 30 to 60 minutes. The consultations will be focused on promoting the adherence to the MedDiet.~The nutritional intervention will be personalized to each individual ad libitum, without calories or macronutrients restriction and without the goal to promote weight change. The intervention will begin with an initial assessment of the dietary patterns of the participants in which the nutritionist will identify potential behavioural changes to promote adjustments in dietary habits and therefore adherence to the MedDiet.~The intervention will promote positive recommendations (behaviours recommended to follow) and negative recommendations (behaviours recommended to reduce or eliminate) (26), using the strategy and MedDiet definition proposed by Estruch et al. in the Primary Prevention of Cardiovascular Disease with a Mediterranean Diet study (3).~The participants will also maintain MDD TAU.
Study: NCT06225752

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo probucol
Description: Inclusion Days 1-30: Placebo Probucol 1000mg/day (500mg per dose, twice daily, a minimum of 4 hours should elapse between each pair of doses.) Inclusion Days 31 and beyond: Placebo Probucol 500mg/day (250mg per dose, twice daily, a minimum of 4 hours should elapse between each pair of doses.)