TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06525545

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: early mobilizzation of the ankle
Description: perform flexion-extension exercises of the operated ankle
Study: NCT04971577

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Simvastatin 40mg
Description: participants will receive a capsule containing 4 tablets simvastatin 10 mg (40 mg total) every 24 hours at night
Study: NCT06663501

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Assisted Motion with Enhanced Sensation training
Description: During the AMES intervention, the AMES device will flex or extend the wrist/hand joint, and the participant's task will be to assist this motion. As the wrist/hand joint moves, the machine will be delivering a vibratory mechanical stimulus on the opposite side to the direction of movement. The activity of the muscles during the movement of the wrist/hand joint will be recorded by the device and it will be shown on a screen to be used as feedback during the training

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Assisted Motion with Enhanced Sensation training
Description: During the AMES intervention, the AMES device will flex or extend the wrist/hand joint, and the participant's task will be to assist this motion. As the wrist/hand joint moves, the machine will be delivering a vibratory mechanical stimulus on the opposite side to the direction of movement. The activity of the muscles during the movement of the wrist/hand joint will be recorded by the device and it will be shown on a screen to be used as feedback during the training
Study: NCT06333496

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: GLP-1 Booster (GB)
Description: GLP-1 Booster (GB) is a composition designed to increase the endogenous production of GLP-1, improve the activity of GLP-1, enhance the body's response to GLP-1, and thus eventually help people reduce glucose, suppress food intake and lose body fat. GB contains Green tea (Camellia sinensis) leaf extract, Gardeniae (Gardenia jasminoides Ellis) fructus extract, Turmeric (Curcuma longa) root extract, Black pepper (Piper nigrum) extract,Fenugreek (Trigonella foenum-graecum) seed extract, Ginseng (Panax ginseng) root extract, and White kidney bean (Phaseolus vulgaris) extract. Each of these ingredients has been commonly consumed by humans as food sources or supplements and thus has an undebatable safety profile.
Study: NCT03972527

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Photobiomodulation
Description: Provide photobiomodulation therapy to subjects prior to each radiation therapy session.
Study: NCT06403956

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training with video
Description: The hand washing skills of the students in the three groups were evaluated by a researcher by observing the hand washing of the students in the sink with the Hand Washing Skills Checklist. After the students were given theoretical information about hand hygiene, including the importance of hand washing, the situations in which hands should be washed, and the steps of hand washing skills, the laboratory practice was started immediately afterwards. In the laboratory, hand washing training was given to the video group with the hand washing video developed by the researchers within the scope of the course. Afterwards, the same researcher who made the first observation re-evaluated the handwashing skills of all students in the sink by filling out the Handwashing Skill Checklist.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training with paint
Description: The hand washing skills of the students in the three groups were evaluated by a researcher by observing the hand washing of the students in the sink with the Hand Washing Skills Checklist. After the students were given theoretical information about hand hygiene, including the importance of hand washing, the situations in which hands should be washed, and the steps of hand washing skills, the laboratory practice was started immediately afterwards. In the laboratory, hand washing training was given to the paint group with the demonstration method using acrylic paint instead of soap. Afterwards, the same researcher who made the first observation re-evaluated the handwashing skills of all students in the sink by filling out the Handwashing Skill Checklist.
Study: NCT05500807

Intervention type: DRUG
Group type: OTHER
Intervention: Emicizumab
Description: Subcutaneous injection of emicizumab for prophylaxis
Study: NCT04985136

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: camrelizumab；Rivoceranib
Description: Camrelizumab at 200 mg via intravenous administration (IV), once every 2 weeks (Q2W), in combination with 250 mg of rivoceranib mesylate, oral administration, once a day (QD)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rivoceranib
Description: Rivoceranib mesylate (750 mg, QD, po)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sorafenib
Description: Sorafenib tosylate (400 mg, twice a day (BID), po)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Regorafenib
Description: Regorafenib (160 mg, administer for 21 days then stop for 7 days, po)
Study: NCT05725421

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Donor Radical and Partial Nephrectomy
Description: Donor participants will undergo laparoscopic radical nephrectomy (RN) . Donor kidney then will undergo cold perfusion and ex-vivo partial nephrectomy (PN) with cold ischemia. During PN, careful inspection of tumor will be performed to ensure it is well-encapsulated. If any infiltrative features (versus well encapsulated tumor) are noted intraoperatively then transplant will not be performed. Multiple surgical margins will be sent (either frozen section or standard with priority). If final margins are positive or concerning, then transplant will not be performed. Biopsies of the tumor will be performed and sent to pathology (either frozen section or standard with priority).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Kidney Transplantation
Description: The donor kidney will remain on ice while pathologic analysis is performed, and transplant recipient surgery is initiated (if pathologic analysis satisfactory). Cold ischemia with delay for pathology will have minimal functional impact in this setting based on extensive prior experience with renal transplantation where kidneys are routinely kept hypothermic for several hours prior to transplantation.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic Radical Nephrectomy
Description: Radical nephrectomy consists of the removal of the kidney together with the perirenal fat and regional lymph nodes. The transperitoneal approach allows early control of the renal vessels.
Study: NCT05080959

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CPL-01
Description: Subjects will receive a single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naropin 150 MG Per 20 ML Injection
Description: Subjects will receive a single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive a single dose
Study: NCT03972527

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Oral Care and Analgesia
Description: Standard oral care, oral hygiene and oral pain protocols

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Oral Care and Analgesia
Description: Standard oral care, oral hygiene and oral pain protocols
Study: NCT04197544

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endoFAVI
Description: EndoFAVI creation to patients that require vascular access for hemodialysis.
Study: NCT06085261

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: home-based telerehabilitation group
Description: Participants will download the web application in their smartphones in the hospital's outpatient clinic and learn to use the sports wristwatch. Remotely supervised telerehabilitation at home will be conducted for 8 weeks, comprising lower limb aerobic training, individualized strength training and respiratory training exercises. The initial aerobic exercise prescription for walking will be set at 80% of the speed walked during a 6-minute walk test (6MWT) and progressed each 4-week according to patient assessments. Resistance training for the arms and legs will utilize elastic bands, while respiratory training will utilize portable breathing trainer. During each training session, participants will be asked to follow the videos in the web application, wearing the sports wristwatch recording their exercise intensity. At the end of every training session, training data could be uploaded to the web platform automatically, which will be checked by staff in hospital.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: center-based traditional rehabilitation group
Description: Participants will undertake an aerobic, strength and respiratory training program of similar intensity and duration to the home-based program, at their site of recruitment.~The initial aerobic exercise prescription for cycling will be set at 60% of the peak oxygen uptake (VO2) on a cardiopulmonary exercise test (CPET). Resistance training and respiratory training are similar to the telerehabilitation group.
Study: NCT05181540

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AB-205
Description: Allogeneic genetically engineered human umbilical vein endothelial cells

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT03972527

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Routine Oral Care and Analgesia
Description: Standard oral care, oral hygiene and oral pain protocols

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Routine Oral Care and Analgesia
Description: Standard oral care, oral hygiene and oral pain protocols
Study: NCT04840706

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HFNC Airvo
Description: HFNC device (Airvo) long-term use in in stabile hypercapnic COPD patients, who are non-compliant to NIV after an acute exacerbation of COPD

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard care
Description: No HFNC treatment
Study: NCT06677892

Intervention type: OTHER
Intervention: No Intervention
Description: This is non-interventional study.
Study: NCT06666231

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: QL (quadratus lumborum) block administration
Description: After endotracheal intubation, patients in the supine position will be given a lateral tilt and the areas to be treated will be cleaned with surgical antiseptic solution. The convex USG probe will be covered in a sterile manner. Then, the sterile probe will be placed transversely on the crista iliaca. The probe will be directed cranially until the external oblique muscle, internal oblique muscle and transverse abdominis muscle are clearly visualized. The psoas major muscle and the transverse process of the vertebra will be visualized. The QL muscle will be visualized between the aponeuros of the transverse abdominis muscle and the psoas major muscle. A 20 G 100 mm block needle will be advanced from posterolateral to anteromedial using the in-plane technique. The needle will be directed between the QL muscle and the psoas major muscles. 20 ml of 0.25% bupivacaine (Buvasin®, Vem İlaç, Turkey) will be injected on each side between the fasciae of these two muscles and the LA distribution

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: External Oblique Intercostal Plane Block
Description: After endotracheal intubation, a 20-gauge 100 mm long block needle will be inserted at the T6-T7 level under USG guidance and bilateral EOIB will be applied with 20 cc of 0.25% Bupivacaine on each side under the external oblique intercostal muscle (total 40ml bilaterally).
Study: NCT05622942

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PBPV
Description: Intramuscular injection, 1 dose of 0.5ml inoculated on day 0

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PPV23
Description: Intramuscular injection, 1 dose of 0.5ml inoculated on day 0
Study: NCT05473000

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Room air
Description: Delivery of room air
Study: NCT05368129

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Balloon dilation
Description: Balloon dilation was performed after DES implantation.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Balloon dilation
Description: Balloon dilation was performed after DES implantation.
Study: NCT05188183

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: M1 anodal home-based tDCS
Description: During tDCS, low amplitude direct currents are applied via scalp electrodes and penetrate the skull to enter the brain. Direct current will be transferred by a saline-soaked pair of surface sponge electrodes (35 cm2) and delivered by a specially developed, battery-driven, constant current stimulator with a maximum output of 10 mA.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Somatosensory Training
Description: The somatosensory training will be performed during the self-administration of tDCS, including 20 sessions over 4 weeks. Sessions will start with relaxation exercises using a body scan technique, whereby subjects in a relaxed state will be instructed to sequentially interchange their mind to different regions of the body while perceiving it and establishing contact with the body part. Subjects will be asked to concentrate on any feeling (kinetic, kinesthetic or exteroceptive) related to each body part. Phantom exercises will involve the use of imagined movements of the phantom limb. Therefore, patients will be asked to perform general exercises with their phantom limb. Exercises will include hip, knee, ankle, and toe movements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Usual care includes pharmacological treatments, physical therapy, occupational therapy and/or behavioral therapy that the subject is receiving.
Study: NCT04588441

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adenosine
Description: Adenosine will be given like an inhaled asthma medication two times daily for one week (7 days). Treatment consists of 9 mg adenosine in 5ml normal saline (NS) administered over 5-10 min via an Aerogen™ nebulizer.
Study: NCT05491239

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic epidural analgesia
Description: After correct placement of the epidural catheter, a local anaesthetic (ropivacaine, levobupivacaine or bupivacaine) will be started and, according to in house protocols, an opioid will be added to the epidural solution. A provisional stop of the administration of the epidural infusion is planned after 48 hours (on the second postoperative day).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continuous regional paravertebral block
Description: The PVB catheter is placed under general anaesthesia at the beginning of the VATS procedure under direct thoracoscopic vision. The level of the PVB catheter placement is chosen at the intercostal space of the largest incision (mostly thoracic level 4 or 5). Under direct thoracoscopic vision, the surgeon inserts a Touhy needle. The tip of the needle is observed beneath the pleural surface thoracoscopically. Injection of about 2 mL ropivacaine 7.5mg/mL will create subpleural hydrodissection to reach the adequate paravertebral plane for placement of the catheter. The PVB catheter is subsequently placed under direct thoracoscopic vision and left next to the sympathetic chain in the paravertebral space. Next, a bolus of ropivacaine (total amount 20 mL including the given amount for hydrodissection) is given through the catheter.~Postoperatively, a ropivacaine 2 mg/mL pump for continuous infusion is given with an infusion rate of 8-14 ml/hour.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single shot intercostal nerve block
Description: At the end of the surgery a single shot ICNB will be placed at 9 levels (thoracic level 2 to 10) with 2-3mL local anaesthetics per intercostal space under direct thoracoscopic vision. The injection site will be chosen just lateral from the sympathetic trunk. This group will have no analgesic catheters for continuous analgesia. No mobility restrictions are instructed in this group.
Study: NCT04997655

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound measurement
Description: In the patient group who will undergo elective laparoscopic cholecystectomy, the diaphragmatic thickness values measured and recorded routinely at the pre-operative, post-extubation and post-operative 30th minute, at the end of inspiration and expiration, and the inspiratory amplitude in m-mode in the ultrasound measured from the right anterior axillary line subcostal area were observed as observational data. will be saved in our file.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound measurement
Description: In the patient group who will undergo elective laparoscopic cholecystectomy, the diaphragmatic thickness values measured and recorded routinely at the pre-operative, post-extubation and post-operative 30th minute, at the end of inspiration and expiration, and the inspiratory amplitude in m-mode in the ultrasound measured from the right anterior axillary line subcostal area were observed as observational data. will be saved in our file.
Study: NCT05760352

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Eccentric bike
Description: Received eccentric cycling exercise

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Eccentric bike
Description: Received eccentric cycling exercise

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Helmet ventilation
Description: Using helmet ventilation during eccentric cycling exercise
Study: NCT06622005

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cxcr1/2 Inhibitor SX-682
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab and Recombinant Human Hyaluronidase
Description: Given SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfilzomib
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo Blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo Bone Marrow Aspiration

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo ECHO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT
Study: NCT06390202

Intervention type: OTHER
Intervention: no intervention
Description: there is no intervention in this study

Intervention type: OTHER
Intervention: no intervention
Description: there is no intervention in this study
Study: NCT06617559

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior Cruciate Ligament Reconstruction with Quadriceps Autograft
Description: The investigators will perform all-inside anterior cruciate ligament reconstruction using only the tendon portion of the quadriceps tendon (without bone fragments) in this group.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior Cruciate Ligament Reconstruction with Hamstring Autograft
Description: The investigators will perform all-inside anterior cruciate ligament reconstruction using the hamstring tendon as a graft in this group.
Study: NCT06617299

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention Identifies and Responds
Description: The treatment of Experimental Group is described, which is made up of eight individual sessions taught over three months. Session one will be in face-to-face format, the content, resources and activities are described in tables 2 and 3. The remaining seven sessions will be follow-up sessions (four sessions by message (WhatsApp®) where motivational messages and reinforcement information will be sent; and 3 sessions by phone call for feedback, see details of time, content, activities and resources in tables 2 and 3.~The design of the intervention is aimed at increasing the practice of Responsive Feeding in mothers with children under 6 months of age, is based on the methodology of Sidani and Braden (2021); on CHW (Bandura, 1986); and behavior change techniques to help people have healthy eating habits (Michie et al., 2011).
Study: NCT06617767

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reiki
Description: The Reiki group received distant Reiki application to their energy centers for 20 minutes, once a day, for 4 consecutive days, by researchers with Reiki Stage II training under the guidance of a researcher with the Usui Reiki Master \& Teacher degree.
Study: NCT05185258

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enstilar
Description: Topical foam

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo-vehicle
Description: Topical foam
Study: NCT06622005

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT06324656

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: crystallized phenol + platelet rich plasma application
Description: At our pilonidal care clinic, patients will undergo a comprehensive treatment regimen starting with manual or laser hair removal to reduce hair by over 90%. For pilonidal abscesses, we will perform incision, drainage, and antibiotic therapy. Treatments will include local anesthesia with lidocaine and epinephrine, thorough disinfection with povidone-iodine, and wound irrigation. Sinuses will be treated by removing hair and curettage, followed by protective ointment application and crystallized phenol to fill the cavity, ensuring precise dosing and safety.~For enhanced healing, crystallized phenol + platelet-rich plasma application patients will receive platelet-rich plasma injections to minimize infection risk and promote tissue regeneration, all under strict sterilization to maintain cleanliness and efficacy.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: crystallized phenol
Description: At our pilonidal care clinic, patients will undergo a comprehensive treatment regimen starting with manual or laser hair removal to reduce hair by over 90%. For pilonidal abscesses, we will perform incision, drainage, and antibiotic therapy. Treatments will include local anesthesia with lidocaine and epinephrine, thorough disinfection with povidone-iodine, and wound irrigation. Sinuses will be treated by removing hair and curettage, followed by protective ointment application and crystallized phenol to fill the cavity, ensuring precise dosing and safety.
Study: NCT06684704

Intervention type: OTHER
Group type: OTHER
Intervention: minimal and high flow anesthesia
Description: Low-flow anesthesia technique is a technique based on the re-breathing of at least half of the gas exhaled in semi-closed systems by returning at least half of the exhaled gas to the patient in the next inspiration.

Intervention type: OTHER
Group type: OTHER
Intervention: minimal and high flow anesthesia
Description: Low-flow anesthesia technique is a technique based on the re-breathing of at least half of the gas exhaled in semi-closed systems by returning at least half of the exhaled gas to the patient in the next inspiration.