TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04659928

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High volume evacuation (HVE)
Description: Intra oral suction will be done and during the procedure,bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab.Patient will be given hydrogen peroxide rinse.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High volume evacuation (HVE)
Description: Intra oral suction will be done and during the procedure,bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab.Patient will be given hydrogen peroxide rinse.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High volume evacuation (HVE)
Description: Intra oral suction will be done and during the procedure,bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab.Patient will be given hydrogen peroxide rinse.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extraoral vacuum aspirator (EVA)
Description: Extraoral suction connected to dental suction will be used and bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab.Patient will be given hydrogen peroxide rinse.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: External evacuation device (EED)
Description: Extraoral suction unit will be used and bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab.Patient will be given hydrogen peroxide rinse.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrogen Peroxide
Description: Subjects will be given 1.5 % Oral Solution of hydrogen peroxide mouth rinse

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrogen Peroxide
Description: Subjects will be given 1.5 % Oral Solution of hydrogen peroxide mouth rinse

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrogen Peroxide
Description: Subjects will be given 1.5 % Oral Solution of hydrogen peroxide mouth rinse
Study: NCT05440669

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: white noise
Description: white noise will reduce pain and stress in nasal cpap application
Study: NCT04821674

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total
Study: NCT06167044

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: thoracic mobilization
Description: Thoracic mobilization will be performed for the thoracic spine mobilization group, thoracic mobilization therapy will be performed for five minutes.
Study: NCT05822531

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Maternal CVH Intervention
Description: All participants will be enrolled into the intervention arm of this pilot study.
Study: NCT05986994

Intervention type: OTHER
Intervention: Metabolic acidosis
Description: Metabolic acidosis at birth with umbilical cord arterial pH at birth \< 7.12

Intervention type: OTHER
Intervention: Metabolic acidosis
Description: Metabolic acidosis at birth with umbilical cord arterial pH at birth \< 7.12
Study: NCT04821674

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total
Study: NCT05679544

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Characterization of early biological effects following exposure to PAHs
Description: Biological samples collected in period of exposure and after holidays
Study: NCT05993780

Intervention type: OTHER
Group type: OTHER
Intervention: No drugs or biologial agents were used in our trial
Description: Before the measurement, a recruitment maneuver was performed for 30-40 s at a PEEP level of 20 cmH2O. At four different PEEP levels of 15, 10, 5, and 0 cmH2O, a decreasing PEEP trial was performed, and the measurement results were recorded.The measurement time at each PEEP level was chosen as 10 minutes. At the end of the measurement, static compliance was measured by applying an end-inspiratory pause. Respiratory system elastance,static strain volume gain was calculated.The estimated lung volume recovered was calculated using the formula ∆EELV - (∆PEEP x Compliance PEEPlow) and compared with the volume gain.
Study: NCT06164223

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VR Baby Pump
Description: VRBaby-Pump application is a video application specially prepared with virtual reality glasses and a milking pump placed inside a toy doll. In the video content, the mother is breastfeeding her baby on an armchair in the baby room prepared for a newborn baby.
Study: NCT06255314

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ventral hernia repair
Description: Laparoscopic transabdominal retromuscular repair is a minimally invasive approach to the open Rives Stoppa retromuscular sublay repair for ventral hernia.~In ventral hernia repair, it relies on initiation of dissection in one retrorectus space and then crossover to the contralateral retrorectus space The sublay mesh technique is an open surgical procedure for ventral and incisional hernias

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ventral hernia repair
Description: Laparoscopic transabdominal retromuscular repair is a minimally invasive approach to the open Rives Stoppa retromuscular sublay repair for ventral hernia.~In ventral hernia repair, it relies on initiation of dissection in one retrorectus space and then crossover to the contralateral retrorectus space The sublay mesh technique is an open surgical procedure for ventral and incisional hernias

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ventral hernia repair
Description: Laparoscopic transabdominal retromuscular repair is a minimally invasive approach to the open Rives Stoppa retromuscular sublay repair for ventral hernia.~In ventral hernia repair, it relies on initiation of dissection in one retrorectus space and then crossover to the contralateral retrorectus space The sublay mesh technique is an open surgical procedure for ventral and incisional hernias
Study: NCT05898555

Intervention type: DEVICE
Intervention: Skiin garment and pods
Description: Participants will be asked to wear a Skiin smart garment over their own clothes.~Small motion capture markers will be placed on their body and pressure-sensitive insoles placed into their shoes to measure the pressure underneath their feet during the study tasks.~Once the sensors are ready for collection, participants will be asked to complete 5 tasks associated with their daily activities: 1. Locomotion; 2. Lower limb strength - repeated sit-to-stand-to-sit transitions; 3. Lower limb strength and locomotion - Timed Up and Go; 4. Free walking during a 2min walk; 5. Standing balance, postural control.
Study: NCT06093178

Intervention type: BEHAVIORAL
Intervention: Human coach-led digital health platform
Description: This is an existing commercial digital platform developed by our technology partners (Empeal). The platform comes in the form of a smartphone app available via Android and Apple devices. Participants will communicate with their coach through the app via video, audio or text. Surveys are conducted on the app. Support content is also available through this app.
Study: NCT05941338

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirelizumab ,+Carboplatin+albumin-bound paclitaxel
Description: Sintilimab (IV), dose= 200mg , day=1 , cycle length: 21 days. Carboplatin (IV), dose=300mg/m2, day= 1, cycle length: 21 days. albumin-bound paclitaxel (IV), dose=260mg/m2, day= 1, cycle length: 21 days. Intervention: Drug: Sintilimab , Carboplatin, albumin-bound paclitaxel
Study: NCT06125587

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chiglitazar
Description: Chiglitazar is a novel PPAR agonist. Treatment of type 2 diabetes mellitus by moderate activation of PPARα, PPARγ and PPARδ, improving insulin sensitivity, regulating blood glucose, and promoting fatty acid oxidation and utilization.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Metformin is not only an antihyperglycemic drug, it also corrects insulin resistance and hyperandrogenism in polycystic ovary syndrome.
Study: NCT05856201

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic cervicosacropexy
Description: The first step consists of a supracervical hysterectomy with morcellation. Anterior and posterior dissection of the vesicovaginal and rectovaginal space. Placing a flexible blade or a Breisky blade in the vagina which is manipulated by the assistant in order to improve exposure of the tissue planes. The retroperitoneum will then be opened from sacral promontory to cervix with the incision just medial to the uterosacral ligament. A low-weight preshaped Y-shaped polypropylene mesh will be secured to the anterior and posterior vagina with four to six separated absorbable 2.0 polyglactin sutures and two nonabsorbable 2.0 prolene sutures can be placed at the level of the remaining cervix. The mesh will be attached to the sacral promontory using two or three nonabsorbable monofilament 2.0 prolene suture. The retroperitoneal space will be closed with continuous 2.0 polyglactin suture or barbed 2.0 absorbable suture material.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Shull technique via V-NOTES
Description: Using a cold-bladed scalpel, pericervical colpotomy and subsequent opening of the Douglas and vesico-uterine space is performed. The following step is forcipressure and section of uterosacral ligaments bilaterally with cold blade scissors and ligation in Polysorb 0. A v-PATH® wall retractor is placed, after insertion of three trocars. Total hysterectomy is then performed by standard V-NOTES technique. After transperitoneal visualization of the ureters bilaterally, the peritoneum is incised between the ureters and the uterosacral ligaments, which are thus bilaterally isolated, and three points in polydioxanone 2/0 are placed per side. The v-PATH wall retractor is then removed. Finally the suspension of the vaginal vault at the uterosacral ligaments is made according to Shull technique. Eventual fascial corrections of concomitant anterior or posterior defects will be associated if needed.
Study: NCT05528679

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 610 100mg
Description: 100mg administered subcutaneously Q4W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 610 300mg
Description: 300mg administered subcutaneously Q4W

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: administered subcutaneously Q4W
Study: NCT05527145

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Minimally invasive surgery
Description: Surgery with decompression. Central decompression of the stenotic segment with undercutting of the lateral recesses.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous Spacer
Description: percutaneous image guided outpatient procedure that enables interspinous spacer insertion and fusion
Study: NCT06305715

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Enrolled subjects will be given radiation doses, at the discretion of the treating physicians, that range from 24-60 Gy in 1-15 fractions with a minimum biologically effective dose (BED\^10) of 58 Gy.
Study: NCT05986994

Intervention type: DIAGNOSTIC_TEST
Intervention: microRNA
Description: Evaluation of microRNA levels

Intervention type: DIAGNOSTIC_TEST
Intervention: microRNA
Description: Evaluation of microRNA levels

Intervention type: DIAGNOSTIC_TEST
Intervention: microRNA
Description: Evaluation of microRNA levels

Intervention type: OTHER
Intervention: Hypothermia
Description: Therapeutic induced hypothermia refers to a lowering of the central body temperature for therapeutic purposes
Study: NCT06305715

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Targeted TKI therapy
Description: Immediately following radiation therapy, subjects with an actionable driver mutation will receive a standard-of-care TKI. The choice of TKI will be at the discretion of the treating oncologist.
Study: NCT00858741

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: single fraction
Description: 8 Gy x 1 fraction to 8 Gy total dose in single dose.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: multiple fractions
Description: 3.0 Gy x 10 fractions to 30.0 Gy total dose in two weeks.
Study: NCT06518317

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin
Description: Short duration of aspirin (3 months) is compared to long duration of aspirin (12 months)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin
Description: Short duration of aspirin (3 months) is compared to long duration of aspirin (12 months)
Study: NCT06537557

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the early in-hospital temperature management protocol for heat stroke patients
Description: The early in-hospital temperature management protocol for heat stroke includes early identification, selection of cooling methods for rapid cooling, precise target temperature management, and dynamic monitoring. Effective temperature management will be implemented for heat stroke patients to improve their outcomes.
Study: NCT05249673

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: global postural reeducation
Description: GPR interventions will last 9 sessions, 1 hour each, with one-to-one supervision, once or twice a week according to the participant's needs. All participants will receive advice to follow written ergonomic suggestions and to repeat the exercises in the first physical therapy session at home twice a week for 15 minutes. Each group will get a home exercise program, which will differ according to the type of treatment received. Participants in the GPR group will execute one posture routine.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: neck stabilization training
Description: Each exercise session will be comprised 10-minute warm-up exercises, 40-minute stabilization exercises, and 10-minute cool-down and stretching exercises, including neck and shoulder girdle muscles. The whole program will be carried out 3 days per week for 4 weeks.~performed. The participants will be asked to maintain the positions and contractions during the exercises and throughout the day as much as possible. The combination and progression of the exercises will be designed according to condition of the patient.
Study: NCT05868005

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical decision support system for screening of migrants using the ISMiHealth software tool.
Description: The implementation of the screening programme will be facilitated using a simple and user-friendly software tool (ISMiHealth).~When an individual attends the PCC for any reason, the tool will generate an alert for health professionals in the EPR system, with recommendations on the conditions that should be considered for screening, based on this patient's characteristics (country of birth, age and sex). Health professionals will decide what diseases/conditions should be screened for, supported by the recommendations of the digital software (intervention centres) or based on their knowledge on the epidemiological background of the diseases (control centres). In any case, health professionals will be responsible for requesting serology tests, chest radiographies and/or referrals to specialists.
Study: NCT06307002

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Playing a contraception education videogame
Description: The WMM game is divided into three parts- a reproductive anatomy quiz (Parts), an interactive tool for education about each individual birth control method (Methods), and a section in which players help avatar couples choose the most effective method for them.
Study: NCT05714618

Intervention type: DIAGNOSTIC_TEST
Intervention: Gadolinium-enhanced cardiac MRI
Description: Cardiac magnetic resonance imaging (MRI) with a protocol designed to measure myocardial inflammation and fibrosis.

Intervention type: DIAGNOSTIC_TEST
Intervention: Gadolinium-enhanced cardiac MRI
Description: Cardiac magnetic resonance imaging (MRI) with a protocol designed to measure myocardial inflammation and fibrosis.
Study: NCT06028022

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mushroom Extract
Description: Given Reishi mushroom extract PO

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mushroom Extract
Description: Given Reishi mushroom extract PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Administration
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Administration
Description: Given PO
Study: NCT05829889

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: FFR-Guided PCI
Description: Fractional Flow Reserve-Guided PCI

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Angiography-Guided PCI
Description: Angiography-Guided PCI
Study: NCT06028022

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05526820

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: The live attenuated varicella vaccine and the inactivated hepatitis A vaccine
Description: The live attenuated varicella vaccine was manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd,the inactivated hepatitis A vaccine was manufactured by Sinovac Biotech Co., Ltd.~The live attenuated varicella vaccine:live varicella-zoster virus in 0.5 mL of sucrose, sodium glutamate,sodium chloride,potassium chloride,sodium dihydrogen phosphate, potassium dihydrogen phosphate and injection water per injection.~The inactivated hepatitis A vaccine:250 U inactivated virus in 0.5mL of aluminium hydroxide solution per injection.~All subjects received hepatitis A vaccine in the upper left arm and varicella vaccine in the upper right arm.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: The live attenuated varicella vaccine and the inactivated hepatitis A vaccine
Description: The live attenuated varicella vaccine was manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd,the inactivated hepatitis A vaccine was manufactured by Sinovac Biotech Co., Ltd.~The live attenuated varicella vaccine:live varicella-zoster virus in 0.5 mL of sucrose, sodium glutamate,sodium chloride,potassium chloride,sodium dihydrogen phosphate, potassium dihydrogen phosphate and injection water per injection.~The inactivated hepatitis A vaccine:250 U inactivated virus in 0.5mL of aluminium hydroxide solution per injection.~All subjects received hepatitis A vaccine in the upper left arm and varicella vaccine in the upper right arm.
Study: NCT05854732

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inclined Treadmill Training
Description: Research subjects will be included in the study according to the inclusion criteria and would be randomized into 2 groups, namely inclined treadmill training group and uninclined treadmill training group and will receive intervention for 6 weeks. The participants will be considered as a experimental group with fixed speed of 5.0 mph and increased inclination of 1% after every one minute. FIIT FORMULA will be considered while providing intervention for 5 days per week to the subjects of each group. The FITT program for the participants will be starting with Warmup of 5 mints with Frequency of 5days/week for 6 weeks with fixed speed of 5.0 mph and increased inclination of 1% after every one minute for 30 minutes ending with Cool down for 5 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Uninclined Treadmill Training
Description: Research subjects will be included in the study according to the inclusion criteria and would be randomized into 2 groups, namely inclined treadmill training group and uninclined treadmill training group and will receive intervention for 6 weeks. The participants will be considered as a active comparator with fixed speed of 5.0 mph and fixed inclination. FIIT FORMULA will be considered while providing intervention for 5 days per week to the subjects of each group. The FITT program for the participants will be starting with Warmup of 5 mints with Frequency of 5days/week for 6 weeks with fixed speed of 5.0 mph and fixed inclination for 30 minutes ending with Cool down for 5 minutes.