TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06361459

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stop smoking
Description: Sine fuma program is offered. nicotine is checked in urine

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stop smoking
Description: Sine fuma program is offered. nicotine is checked in urine
Study: NCT05284110

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Multiple bouts of 3-min brisk walking, every 30 min, for 4 hours.
Study: NCT06070610

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1015550
Description: BI 1015550
Study: NCT05710354

Intervention type: DIETARY_SUPPLEMENT
Intervention: Nutridrink Compact Protein
Description: Oral Nutritional Supplement, a liquid, ready-to-drink, high protein, high calorie blend. Intended for adult patients (from 18 years of age) with malnutrition or risk of its development. Produced by Nutricia
Study: NCT04789434

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 Inhibitor Tislelizumab maintenance therapy
Description: PD-1 Inhibitor Tislelizumab maintenance therapy, 200mg, every 2 months, 12 times
Study: NCT05451264

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: blood pressure measurement
Description: Completion of the physical activity and quality of life questionnaire (PedSQL adapted to the age of the child), measurement of weight and height; Measurement of VOP (Pulse wave velocity), AI (increase index) and ECG (electro cardiogram) collection at rest lying down; Stimulation test by slow breathing at 6 cycles/min for three minutes; Continuation of the measurements in a standing position for 5 minutes; Installation of blood pressure holter (MAPA) which will be kept for 24 hours and then returned by post.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: blood pressure measurement
Description: Completion of the physical activity and quality of life questionnaire (PedSQL adapted to the age of the child), measurement of weight and height; Measurement of VOP (Pulse wave velocity), AI (increase index) and ECG (electro cardiogram) collection at rest lying down; Stimulation test by slow breathing at 6 cycles/min for three minutes; Continuation of the measurements in a standing position for 5 minutes; Installation of blood pressure holter (MAPA) which will be kept for 24 hours and then returned by post.
Study: NCT06070610

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nintedanib
Description: Soft capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirfenidone
Description: Film-coated tablets
Study: NCT06592222

Intervention type: DRUG
Intervention: Elranatamab
Description: BCMA-CD3 bispecific antibody

Intervention type: DRUG
Intervention: Standard of care
Description: Standard of care
Study: NCT05129176

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levofloxacin
Description: levofloxacin-tetracycline-containing quadruple regimens
Study: NCT06404008

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST
Description: After randomization, individuals will attend an in-person training session in the REST protocol. This is a 15 minute controlled breath protocol that includes 3 yoga breathing techniques: 3-part dirgha breath, alternate nostril breathing, and 2:1 breathing. Each technique will be completed for 5 minutes, for a total of 15 minutes. After the training session, participants will practice the REST protocol for 15 minutes twice a day with guidance from research staff over zoom (Days 1-7) with daily COPD education including inhaler technique, nutrition, vaccinations, tobacco cessation counseling, and exacerbation education. On Day 8, participants will attend the Trial Session where they will complete the REST protocol (15 minutes) while vitals, lung function, and ECG measurements are taken. Surveys will be administered before and after the REST protocol to document patient reported stress and dyspnea.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: After randomization, individuals will attend an in-person education session led by a research coordinator. For the following 7 days, the research staff will call patients daily and provide daily COPD education including inhaler technique, nutrition, vaccinations, tobacco cessation counseling, and COPD exacerbation education. On Day 8, participants will attend the Trial Session where they will do spontaneous breathing (15 minutes) while vitals, lung function, and EKG measurements are taken. Surveys will be administered before and after the spontaneous breathing period to document patient reported stress and dyspnea. After the study, participants will be asked to complete a close out survey and interview over zoom.
Study: NCT05733481

Intervention type: DEVICE
Group type: OTHER
Intervention: CapBuster System Medical Device for the Crossing of Chronic Total Occlusions in Coronary Arteries
Description: The CapBuster System is a medical device intended to facilitate the intraluminal placement of conventional guidewires beyond chronic total occlusions prior to the utilization of interventional devices. The device system, manufactured by Praxis Medical, comprises the CapBuster support catheter and CapBuster penetrating wire which are mated together with a screw thread.
Study: NCT05763940

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: OmegaBoost
Description: An ultra-pure omega-3 fish oil supplement with no fishy aftertaste and no fish burps.~10x more omega-3 from fish oil than the leading omega-3 gummies. Gel bites have better absorption than ordinary, hard-to-swallow fish oil pills.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: OmegaBoost
Description: An ultra-pure omega-3 fish oil supplement with no fishy aftertaste and no fish burps.~10x more omega-3 from fish oil than the leading omega-3 gummies. Gel bites have better absorption than ordinary, hard-to-swallow fish oil pills.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nature Made (soft gel)
Description: A commercially-available omega-3 soft gel formula

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nature Made (gummy)
Description: A commercially-available omega-3 formula in gummy form
Study: NCT05235256

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: bilateral sphenopalatine ganglion block
Description: peripheral n block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: bilateral greater occipital nerve block
Description: bilateral greater occipital nerve block
Study: NCT05546788

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: scaling and root planing
Description: subgingival Depridement
Study: NCT05235256

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: lidocaine plus dexamethasone
Description: lidocaine plus dexamethasone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: lidocaine plus dexamethasone
Description: lidocaine plus dexamethasone
Study: NCT05615961

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics (Lab4 probiotics, Cultech, Port Talbot, Wales, UK)
Description: The intervention is a unique blend of probiotic cultures from a well-established manufacturer.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo Tablets
Study: NCT04993911

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Group
Description: Assessment will be performed pre and post of intervention. Intervention will be given 3 days a week for 8 weeks. Each session will include a 5-min warm-up on a fitness bike or treadmill before commencement of the program and a 5-min cool period. Participants of this group will receive balance training with conventional treatment. Participants will perform between 2 sets of 5 and 7 repetitions of each exercise.~Single leg balance~* Walking forward~* Walking backward~* Side stepping~* Walk heel to toe~* Static exercises with eyes close or open~CONVENTIONAL EXERCISE PROGRAM :~* TENS for 15 minutes~* Hot pack for 15 minutes~* Participants will perform between 2 sets of 7 and 10 repetitions of each exercise:~* Quadriceps/hamstring isometric exercises.~* ROM and active stretching of the hamstring and quadriceps muscle.~* Active ankle pump.~* Squats,step-up, sit to stand, calf raises~* Straigh leg raising exercise in crook lying position

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: Participants of this group will receive only conventional therapy which will include; before beginning the program, each session will feature a 5-minute warm-up on a fitness bike or treadmill, followed by a 5-minute cool-down. Participants of this group will receive only conventional therapy which will include.~* CONVENTIONAL EXERCISE PROGRAM :~* TENS for 15 minutes~* Hot pack for 15 minutes~* Participants will perform between 2 sets of 7 and 10 repetitions of each exercise:~* Quadriceps/hamstring isometric exercises.~* ROM and active stretching of the hamstring and quadriceps muscle.~* Active ankle pump.~* Squats,step-up, sit to stand, calf raises~* Straigh leg raising exercise in crook lying position
Study: NCT05440773

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artemisia afra tea infusions
Description: A. afra infusions of 5g/1litter of water, 3drinks a day, daily for 1week (7 days) (current recommendation).
Study: NCT05129176

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metronidazole
Description: Metronidazole-tetracycline-containing quadruple regimens
Study: NCT06422520

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BGB-C354
Description: Administered by intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BGB-C354
Description: Administered by intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BGB-C354
Description: Administered by intravenous infusion
Study: NCT05546788

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: scaling and root planing
Description: subgingival Depridement

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: scaling and root planing
Description: subgingival Depridement

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: hydroxylated poly methoxy flavones
Description: Received hydroxylated poly methoxy flavones extract solid dispersion incorporated into sodium carboxymethylcellulose gel
Study: NCT06422520

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BGB-C354
Description: Administered by intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Administered by intravenous infusion
Study: NCT06740149

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bone marrow mesenchymal stem cells (medium dose)
Description: Administered intravenously. For phase I: single infusion, 2.0×10\^6 cells /kg. For phase II: 2.0×10\^6 cells /kg once a week for a total of 4 times.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bone marrow mesenchymal stem cells (high dose)
Description: Administered intravenously. For phase I: single infusion, 4×10\^6 cells /kg.
Study: NCT05014542

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture treatment includes pricking the skin with acupuncture needles 0.3 x 40 millimetres in size, in the places of prescribed acupuncture points. Placed needles should be manipulated three times, every ten minutes, three times in total. The complete time of treatment is 30 minutes. All treatments will be equal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Conventional Medical Treatment
Description: Participants could take their standard conventional medical treatment or analgesics. Analgesics therapy is prescribed by their general practitioner. The dose of analgesics could be modified according to participants' symptoms intensity.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Medical Treatment
Description: Participants could take their standard conventional medical treatment or analgesics. Analgesics therapy is prescribed by their general practitioner. The dose of analgesics could be modified according to participants' symptoms intensity.
Study: NCT05546788

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: chlorhexidine
Description: Received chlorhexidine gel
Study: NCT05440773

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artemisia afra tea infusions
Description: A. afra infusions of 5g/500ml of water, 2drinks a day, daily for 1week (7 days) (increase concentration and decrease dose frequency).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artemisia afra tea infusions
Description: A. afra infusions,5g/1liter of water, 3drinkss a day, weekly for 4weeks (decrease dose frequency and increase length of treatment).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artemisia afra tea infusions
Description: A. afra infusions, 5g/1liter of water, 3drinks a day, daily for1week (7 days) (current treatment with improved taste).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artemisia afra tea infusions
Description: A. afra infusions, 5g/500ml of water, 2drinks a day, daily for 1 week (7 days) (improved taste, increase concentration and decrease dose frequency).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artemisia afra tea infusions
Description: Group of 8 persons receiving flavored A. afra infusions, 5g/1liter of water, 3drinks a day, weekly for 4weeks (improved taste, decrease dose frequency and increase length of treatment).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Flavored placebo infusions
Description: Flavored placebo infusions, 5g/liter of water, 3drinks a day, daily for 1week (7 days) (improved taste with no active molecule)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Regular tea placebo
Description: Regular tea placebo taken as desired, daily for 1 week (7 days) (Regular tea with no active molecule).
Study: NCT06023576

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: antihypertensive medications
Description: One or more of the following medications may be used in both randomization groups to achieve SBP goals:~* Angiotensin converting enzyme inhibitors (ACEI)~* Angiotensin receptor blockers (ARBs)~* Beta-blockers (BB)~* Thiazide-type diuretics~* Calcium channel blockers~* Aldosterone antagonists~* Alpha1-receptor blockers.~* Direct vasodilators~* Loop diuretics

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: antihypertensive medications
Description: One or more of the following medications may be used in both randomization groups to achieve SBP goals:~* Angiotensin converting enzyme inhibitors (ACEI)~* Angiotensin receptor blockers (ARBs)~* Beta-blockers (BB)~* Thiazide-type diuretics~* Calcium channel blockers~* Aldosterone antagonists~* Alpha1-receptor blockers.~* Direct vasodilators~* Loop diuretics

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood pressure measurement
Description: Home BP Monitoring (HBPM)-Throughout the study period, patients will perform HBPM at baseline, month 6, and month 12 (end of treatment). At each of these timepoints, HBPM will be performed for 7 days with 2 morning and 2 evening readings for each day (measured 1-min part).
Study: NCT06739837

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: traditional physiotherapy
Description: Participants in this arm will undergo traditional physiotherapy exercises for managing tennis elbow.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Non-immersive VR therapy
Description: Participants undergo a VR-based rehabilitation program targeting tennis elbow symptoms. Sessions last 30 minutes, conducted 3 times per week for 6 weeks. Exercises focus on improving grip strength, wrist flexibility, and functional movement through interactive VR environments that visually engage the affected arm, promoting adherence and motivation without full immersion. The VR setup includes headsets or screens that enable visual interaction, enhancing the rehabilitation experience. The goal is to alleviate pain, increase range of motion, and restore muscle strength.
Study: NCT06741007

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Retroperitoneal pelvic lymphatic and uterine vessel dissection
Description: ICG injection to cervix uteri at 3 and 9 o'clock followed by laparoscopic dissection of retroperitoneal space to detect uterine vessels (uterine arteries, SUVs and DUVs) bilaterally in addition to detect the location and biopsy of SLN stained by ICG.
Study: NCT06739746

Intervention type: OTHER
Intervention: No intervention measures
Description: No intervention measures

Intervention type: OTHER
Intervention: No intervention measures
Description: No intervention measures
Study: NCT06740123

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nonsurgical periodontal treatment and application of H42® hydrogel to the peri-implant pocket
Description: Firstly, after appropriate oral hygiene training, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of peri-implant pocket areas between 5-8 mm in the contralateral quadrant. The tested site will be partially isolated and then air-dried. A bent, blunt-tipped needle syringe will be used to inject the H42® hydrogel into the pocket, ensuring that the tip reaches the deepest point of the pocket. Once the gel is visible at the gingival margin, the needle will be gently removed from the pocket. After approximately 0.1 mL of gel has been applied, excess gel will be removed with a sterile gauze swab to prevent any spreading effect or possible systemic effect. After application of the H42 hydrogel, the area will be kept dry for 5 minutes to ensure optimum adhesion of H42 to the pocket tissue.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nonsurgical periodontal treatment of periodontal pocket
Description: Systemic and dental anamnesis will be taken from all patients. Firstly, after appropriate oral hygiene education, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of periodontal pocket areas between 5-8 mm in the contralateral quadrant.
Study: NCT06023576

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood pressure measurement
Description: Home BP Monitoring (HBPM)-Throughout the study period, patients will perform HBPM at baseline, month 6, and month 12 (end of treatment). At each of these timepoints, HBPM will be performed for 7 days with 2 morning and 2 evening readings for each day (measured 1-min part).

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Echocardiogram
Description: At baseline, month 6, and month 12

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Echocardiogram
Description: At baseline, month 6, and month 12

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Symptom-limited cardiopulmonary exercise test
Description: Consecutive patients in each treatment group who meet the eligibility criteria for exercise testing will be offered to participate in CPET at the time of consent. Patients who agree will undergo CPET (baseline, 6 months, and 12 months) until the target accrual of 33 patients per group is met.
Study: NCT06740123

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non-surgical periodontal treatment and application of H42® hydrogel to the periodontal pocket
Description: Firstly, after appropriate oral hygiene training, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of periodontal pocket areas between 5-8 mm in the contralateral quadrant. The tested site will be partially isolated and then air-dried. A bent, blunt-tipped needle syringe will be used to inject the H42® hydrogel into the pocket, ensuring that the tip reaches the deepest point of the pocket. Once the gel is visible at the gingival margin, the needle will be gently removed from the pocket. After approximately 0.1 mL of gel has been applied, excess gel will be removed with a sterile gauze swab to prevent any spreading effect or possible systemic effect. After application of the H42 hydrogel, the area will be kept dry for 5 minutes to ensure optimum adhesion of H42 to the pocket tissue.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nonsurgical periodontal treatment of peri-implant pocket
Description: Systemic and dental anamnesis will be taken from all patients. Firstly, after appropriate oral hygiene education, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of peri-implant pocket areas between 5-8 mm in the contralateral quadrant.
Study: NCT06736782

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Empowerment Care Intervention Group
Description: The intervention emphasizes four key principles: hydration, exercise, dietary support, and defecation care. Each component is designed to address fundamental needs and promote independence in activities of daily living (ADLs).~Individualized care plans will be developed in collaboration with healthcare professionals and caregivers to ensure alignment with participants' functional capabilities and personal goals.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: Standard caregiving practices without emphasis on structured hydration, exercise, or dietary programs.~General assistance with ADLs as per existing care routines in the respective facilities.
Study: NCT06736951

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MMSH (Multi-Modal Sleep Hygiene) Bundle
Description: Focus on Noise Reduce Noise Perception, Reduce Hallway Noise, Reduce Noise in Rooms Focus on Light Reduce Lights at Night, Increase Light in Day, Reduce Light Perception Focus on Staff-Patient Interactions Delirium Screening, Avoid Care Procedures at Night, Z-time Plan \&amp; Prep Focus on Daytime Activity Increased Mobility, Increase Patient Engagement Focus on Medications Pain Management, Medication Monitoring, Continue pharmacy protocols, Timing of Medications/Monitoring Labs