TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06614166

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SBD111 Probiotic Medical Food
Description: Medical food comprised of probiotics and prebiotic fibers

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SBD121 Probiotic Medical Food
Description: Probiotic medical food comprised of three lactic acid bacteria and one bacillus
Study: NCT06615063

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hasi's Splint
Description: A splint made up of cotton and gauze piece rolled over a hard cardboard piece and covered by adhesive tape was applied to the limb immediately after fixing the cannula, as per the standardised method, to prevent movement at the underlying joint. Dimensions of the splints used were standardised as length extending two and a half inches on either side of the joint and width equal to the width of the limb just proximal to the joint.
Study: NCT04854486

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GSE and Xylitol
Description: Participants are given the experimental treatment to be used for 7 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Control Placebo
Description: Saline
Study: NCT06623292

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motivational interviewing-based breastfeeding education
Description: This program includes breastfeeding motivational interviewing consisting of a total of 4 sessions and breastfeeding education consisting of one session.
Study: NCT04791345

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: 2 mg of dexamethasone (1/2 pill) administered orally every 12 hours during 5 days.
Study: NCT05642533

Intervention type: OTHER
Intervention: No treatment given
Description: No treatment given

Intervention type: OTHER
Intervention: No treatment given
Description: No treatment given
Study: NCT06644690

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CO-OP Only
Description: The CO-OP Only intervention involves the Cognitive Orientation to daily Occupational Performance (CO-OP) approach, which is designed to improve cognitive and functional performance through structured goal-setting, problem-solving, and metacognitive strategies. Participants engage in activities focused on improving their ability to perform daily tasks by using cognitive tools to develop and execute solutions. The intervention is administered three times per week for 60 minutes over an 8-week period. No additional physical or dance activities are included in this arm.
Study: NCT06644352

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: different thoracic surgical approaches
Description: Right Versus Left Thoracic Surgical Approaches

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: different thoracic surgical approaches
Description: Right Versus Left Thoracic Surgical Approaches
Study: NCT05607849

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The decidons ensemble (let's decide together) leaflet and the discutons-mammo.fr (let's talk about breast cancer screening) online tool.
Description: The leaflet will include a link to access the discutons-mammo.fr DA aid tool, and will inform women about shared decision-making.~The GPs of women who are sent the leaflet will also be sent a letter encouraging shared decision-making. This material will be sent 3 months after women have received their breast cancer screening invitation letter.~Data related to primary and secondary objectives will be collected by questionnaire from the 2 groups. The questionnaire will be sent 2 months after participants are informed about the tool.
Study: NCT05486065

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Semaglutide s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.
Study: NCT05169073

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Virtual Reality training
Description: In the Virtual Reality (VR) study arm, a VR software (Specto VRTM, version 4.0, Diffuse Ltd, Heimberg, Switzerland) will be used to display volumetric MRCP data using a tethered head-mounted display (HMD) prior to the operation. Specto uses volume rendering at 180 frames/sec to visualize the medical data in an immersive fashion in the VR environment and allows for viewing of the 3D reconstructed 3D imaging with 360° free movement. Each participant will perform a procedure with VR training and one with conventional preparation (MRCP).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional training
Description: In the conventional study arm, the participants will view the preoperative MRCP.
Study: NCT05486065

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Semaglutide s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Semaglutide s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Semaglutide placebo s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Semaglutide placebo s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.
Study: NCT06131320

Intervention type: DIAGNOSTIC_TEST
Intervention: PVSE Test
Description: Completion of the PVSE test
Study: NCT05486065

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Semaglutide placebo s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.
Study: NCT06622941

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-4538
Description: every 2 weeks
Study: NCT06693739

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Platelet rich fibrin
Description: PRF membrane is placed as a scaffold inside the canal with no hyaluronic acid

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hyaluronic acid
Description: hyaluronic acid gel is placed as a scaffold inside the canal with no PRF

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: no scaffold
Description: initiate bleeding using hand files size beyond apex with sharp strokes with no PRF or hyaluronic acid placed
Study: NCT06628401

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Educational information (Control)
Description: Information packs will be developed for participants outlining the importance of a control group in research studies to maximise compliance. Participants will receive a £10 gift voucher weekly that they can spend at selected retailers of their choosing.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational information (Increasing F&V intake)
Description: Information packs will be developed to support participants in increasing their intake of whole fruits and vegetables, excluding fruit juice. The information packs will be developed using published guidance from the UK government, expert panels, and regulatory bodies. The packs will be co-developed with the public to ensure the guidance is appropriate for its target audience. Participants will also receive a £10 supermarket voucher weekly to purchase fruit and vegetables.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational information (Increasing F&V intake + Juice)
Description: Information packs will be developed to support participants in increasing their intake of whole fruits and vegetables, including fruit juice. The information packs will be developed using published guidance from the UK government, expert panels, and regulatory bodies. The packs will be co-developed with the public to ensure the guidance is appropriate for its target audience. Participants will also receive a £10 supermarket voucher weekly to purchase fruit and vegetables.
Study: NCT06629766

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microfluidic sperm separation device
Description: An aliquot of 850ul will be used for the Zymot sperm selection device. The sperm processing via Zymot will be per manufacturer's guidelines

Intervention type: OTHER
Group type: OTHER
Intervention: Density grade centrifugation
Description: 5ul of the ejaculated sample will be assessed for DGC via Makler assessment. If the sample for DGC is adequate per lab standard operating procedures, then routine DGC sperm preparation and embryologist sperm selection for the ICSI procedure will occur.
Study: NCT06613477

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PK/PD Model Based Dosing of Digoxin in Infants with Single Ventricle Heart Disease
Description: Table 3: Digoxin dosing regimen based on optimized Cmin,ss Dose to be given twice daily (mcg/kg/dose) PNA\<30 days 30 days \< PNA \< 180 days eGFR≤40 1.4 1.4 40\<eGFR≤60 1.6 1.6 eGFR\>60 1.9 2.8
Study: NCT06473103

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Two photon fluorescence microscopy imaging
Description: Excised tissues will be imaged with two photon fluorescence microscopy prior to submission for histological processing.
Study: NCT06672822

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Thiosulfate (STS)
Description: Depending on the size of the calcinosis lesion, 1-5ml of STS (250mg/ml) will be used for injection under ultrasound guidance.
Study: NCT06628661

Intervention type: PROCEDURE
Intervention: Surgery for HCC larger than 6.5 cm
Description: Surgery for HCC larger than 6.5 cm without mVI
Study: NCT06673823

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mirror therapy
Description: Mirror Therapy (MT) is a non-invasive treatment method aimed at addressing unilateral conditions impacting either the upper or lower limbs. This technique involves placing a mirror along the patient's sagittal plane, allowing the reflection of the unaffected limb to visually overlay the affected limb.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: conventional therapy
Study: NCT06675279

Intervention type: OTHER
Intervention: Survey-based study
Description: The demographic information of individuals with migraines, along with data from the Visual Analog Scale, Migraine Disability Assessment Questionnaire, Headache Impact Test, Henry Ford Hospital Headache Disability Inventory, and Headache Needs Assessment, will be collected and analyzed.
Study: NCT06675422

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JY231 injection
Description: Dose escalation was carried out using the 3+3 principle and the mode of administration was intravenous.
Study: NCT06674317

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet Delivered Cognitive Behavioral Therapy for Insomnia in Persons with Inflammatory Rheumatic Diseass
Description: Cognitive behavioral therapy for insomnia (CBTi) is considered a first-line treatment for insomnia. Access to this treatment option is limited therefore we have been developing an internet delivered cognitive behavioral therapy for insomnia (I-CBTi) to help overcome accessibility barriers.~The purpose of this study is to pilot test a tailored internet-delivered cognitive behavioral therapy for insomnia (I-CBTi) intervention for persons with Inflammatory Rheumatic Diseases showing symptoms of insomnia.
Study: NCT06628661

Intervention type: PROCEDURE
Intervention: Surgery for HCC larger than 2 cm
Description: Surgery for HCC larger than 2 cm with mVI
Study: NCT06674317

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Internet Delivered Cognitive Behavioral Therapy for Insomnia in Persons with Inflammatory Rheumatic Diseass
Description: Cognitive behavioral therapy for insomnia (CBTi) is considered a first-line treatment for insomnia. Access to this treatment option is limited therefore we have been developing an internet delivered cognitive behavioral therapy for insomnia (I-CBTi) to help overcome accessibility barriers.~The purpose of this study is to pilot test a tailored internet-delivered cognitive behavioral therapy for insomnia (I-CBTi) intervention for persons with Inflammatory Rheumatic Diseases showing symptoms of insomnia.
Study: NCT06675045

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Respiratory variability monitoring
Description: Respiratory variability will be measured using a belt equipped with an external sensor allowing automatic and continuous analysis of thoracic movement by frequency analysis
Study: NCT05760755

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stick Together
Description: The intervention consists of 12 online modules, completed flexibly during and immediately after primary cancer treatment. The intervention contains interviews with other couples, psychoeducational information, and interactive exercises on themes such as dyadic coping and communication, being diagnosed at a young age, fertility and children, and life after treatment.
Study: NCT06698172

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality rehabilitation
Description: The study includes 12 weekly 45-minute visual rehabilitation sessions using a Virtual Reality device with Visionary Sport software. Originally designed for sports visual training, this software features gamified exercises to improve visual response times under professional supervision. Activities include games to enhance fixation, ocular motility, peripheral vision, and vergence.~The Peripheral Attention activity trains reaction times to static stimuli perceived in the peripheral retina, adjustable to the patient's visual field defect. Stimuli can be placed at 10, 20, or 30 degrees in the peripheral field. The VR headset (Vive Focus 3) includes an eye tracker to monitor and adapt stimuli based on patient performance.~Patients also perform 30 minutes of daily exercises at home, using proprietary software and Tobii 4C and 5C eye-tracking devices for ocular monitoring.
Study: NCT06697145

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cardioneuroablation
Description: Ablation of parasympathetic ganglia of the heart
Study: NCT06696820

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PCSK9 inhibitors combined with atorvastatin/rosuvastatin
Description: A single subcutaneous injection of 420 mg Iroceliumab upon admission, along with a standard dose of 20 mg Atorvastatin or 10 mg Rosuvastatin

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Atorvastatin/Rosuvastatin
Description: Conventional Atorvastatin 20 mg / Rosuvastatin 10 mg
Study: NCT06696209

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy
Description: Time of last esophageal image - time of first image of the second portion of the duodenum.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Analysis of the total time of the Upper Gastrointestinal Endoscopy
Description: Time of last esophageal image - time of first esophageal image

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Upper gastrointestinal endoscopy: Common Practices
Description: Execution of UGE using high-resolution endoscopes, with the option of virtual chromoendoscopy, according with the physician's preference. Possible optimization of visualization with washing and/or the use of simethicone or similar, as pre-medication or during the examination, according with the physician's preference. Patients will be randomised to one of the following measurements-total time versus withdrawal time-in a parallel 1:1 scheme.~The allocation of the randomisation group will be computer-generated. The endoscopist must record the time at which the following three anatomical structures are reached (either by noting during the procedure or based on the information in the photographic documentation), before any biopsies or therapeutic interventions, in the format xxh:xxmin:xxsec:~1. First esophageal image;~2. First image of the second portion of the duodenum;~3. Last esophageal image.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Upper gastrointestinal endoscopy: Common Practices
Description: Execution of UGE using high-resolution endoscopes, with the option of virtual chromoendoscopy, according with the physician's preference. Possible optimization of visualization with washing and/or the use of simethicone or similar, as pre-medication or during the examination, according with the physician's preference. Patients will be randomised to one of the following measurements-total time versus withdrawal time-in a parallel 1:1 scheme.~The allocation of the randomisation group will be computer-generated. The endoscopist must record the time at which the following three anatomical structures are reached (either by noting during the procedure or based on the information in the photographic documentation), before any biopsies or therapeutic interventions, in the format xxh:xxmin:xxsec:~1. First esophageal image;~2. First image of the second portion of the duodenum;~3. Last esophageal image.
Study: NCT06697288

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tested product group
Description: Apply the test product per zone at least twice a day on the face, neck (neck \& nape), décolleté and back of the hand in the morning and at midday whatever the weather conditions and the activities of the day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: Maintain their normal routine of using cosmetics (cleansers and moisturizers) and normal sun protection habits (if applicable)
Study: NCT06698107

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Childbirth education programme
Description: The intervention framework is underpinned by a converging of salutogenic and self-efficacy perspectives, aiming to enhance mothers' ability to adapt to new motherhood life despite stressors, and to address the question, How do teenage mothers stay well despite stressful events of transition to motherhood? The intervention consists of six sessions: three of which will be provided in the antenatal period and the other three in the postpartum period. The sessions contain two individual face-to-face educations (each lasting 60-90 minutes), two phone calls (each lasting 30 minutes), and two group discussion sessions (each lasting 90-120 minutes), as supported by the existing evidence.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: The control group will receive the usual maternity care.
Study: NCT06696833

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: QH10304-BAL-01
Description: dose escalation (3+3) : dose 1 (3 × 10\^8cells/kg) ,dose 2 (1 × 10\^9 cells/kg) ,dose 3 (3 × 10\^9cells/kg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Intravenous fludarabine 30mg/m2 on days-6 to -3,the infusion dose is adjusted according to the subject's condition
Study: NCT05465408

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally Aware Adjuvant Endocrine Therapy (AET) Non-Initiation Intervention
Description: One-to-One virtual (videoconference) behavioral intervention.
Study: NCT06677554

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Addition of ultrasound with contrast injection (SonoVue®)
Description: Addition of contrast evaluation with SonoVue® injection (5 min including 1 min of acquisition) within the diagnostic strategy

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care (in control arm)
Description: No addition of ultrasound with contrast
Study: NCT06671496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zasocitinib
Description: Zasocitinib tablets.
Study: NCT06696833

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Intravenous cyclophosphamide 1000mg/m2 on days -5 to -3, the infusion dose is adjusted according to the subject's condition
Study: NCT06697002

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: lower trapezius strenghtening excercise
Description: 32 participants will be in control group who will perform strenghtening excerise of lower trapezius
Study: NCT05947097

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542 Injection
Description: 1ug/kg bolus for 2min±5s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542 Injection
Description: 1ug/kg bolus for 2min±5s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542 Injection
Description: 1ug/kg bolus for 2min±5s

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542 Injection
Description: 1ug/kg bolus for 2min±5s
Study: NCT04791371

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cardiovascular exercise
Description: 15 weeks of cardiovascular exercise 3x/week for 50 minutes/session

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cardiovascular exercise
Description: 15 weeks of cardiovascular exercise 3x/week for 50 minutes/session
Study: NCT06697002

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: scapular mobility exercise
Description: 32 participants will be in experimental group who will perform scapular mobility exercise
Study: NCT06697548

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain Neuroscience Education
Description: Participants will watch and discuss a short (5-minute) standardized pain neuroscience education video with their treating provider. The video explains and illustrates how chronic pain is different than acute pain in that it concerns nervous system hypersensitivity more than local tissue damage. Pain neuroscience education principles from the video will then be used to throughout all interventions to coach the participants through graded exposure of activities that may have previously been painful or provoked anxiety.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pain Neuroscience Education
Description: Participants will watch and discuss a short (5-minute) standardized pain neuroscience education video with their treating provider. The video explains and illustrates how chronic pain is different than acute pain in that it concerns nervous system hypersensitivity more than local tissue damage. Pain neuroscience education principles from the video will then be used to throughout all interventions to coach the participants through graded exposure of activities that may have previously been painful or provoked anxiety.
Study: NCT06671496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Zasocitinib matching placebo.