TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06497790

Intervention type: DIAGNOSTIC_TEST
Intervention: Flexible Endoscopic Evaluation of Swallowing
Description: The FEES evaluates anatomical changes, functional disorders of the visible structures (e.g. recurrent paresis), saliva management, penetration and aspiration of food boluses in order to draw conclusions about the underlying pathomechanism of dysphagia. It is an established standard diagnostic procedure for stroke patients and, in addition to the diagnosis of dysphagia, also enables pathomechanism-guided therapy by speech therapists

Intervention type: DIAGNOSTIC_TEST
Intervention: Flexible Endoscopic Evaluation of Swallowing
Description: The FEES evaluates anatomical changes, functional disorders of the visible structures (e.g. recurrent paresis), saliva management, penetration and aspiration of food boluses in order to draw conclusions about the underlying pathomechanism of dysphagia. It is an established standard diagnostic procedure for stroke patients and, in addition to the diagnosis of dysphagia, also enables pathomechanism-guided therapy by speech therapists
Study: NCT04909671

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gi Genius, Medtronic
Description: GI geniusTM (Medtronic) is an artificial intelligence device designed and validated on a dataset of white-light endoscopy videos from high-quality randomized controlled trials for the detection of colorectal lesions during colonoscopy. Based on a deep learning system using convolutional neural networks, GI genius works in real-time side-to-side with the gastroenterologist during colonoscopy highlighting the presence of precancerous lesions with a visual marker (green box) in real time and designed to be integrated with the majority of colonoscopies.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: White light standart colonoscopy
Description: High definition white light endoscopy will be used during the scope withdrawal
Study: NCT06208878

Intervention type: OTHER
Intervention: Non Interventional
Description: Safety and Efficacy Assessment
Study: NCT06467214

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CONNECTED
Description: CONNECTED is a manualized, peer-led, group-based social isolation intervention for diverse veteran populations in VA primary care settings. It is delivered via videoconference through individual and group sessions over 8 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: VET BEFRIENDING
Description: VET BEFRIENDING (attention control arm) consists of weekly social interactions with a research assistant (RA) over videoconference or phone.
Study: NCT05479747

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: post operative analgesics
Description: post-operative pain killer

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: post operative analgesics
Description: post-operative pain killer

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: post operative analgesics
Description: post-operative pain killer

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: post operative analgesics
Description: post-operative pain killer
Study: NCT05157737

Intervention type: OTHER
Intervention: Electrophysiological detection of KCNQ2 mutation
Description: Electrophysiological detection of KCNQ2 mutation performed using patch clamp technique in an in vitro cell model. Analyze the association between phenotype and genotype.

Intervention type: OTHER
Intervention: Electrophysiological detection of KCNQ2 mutation
Description: Electrophysiological detection of KCNQ2 mutation performed using patch clamp technique in an in vitro cell model. Analyze the association between phenotype and genotype.

Intervention type: OTHER
Intervention: Multi-modal brain image and EEG
Description: Multi-modal brain image include brain magnetic resonance imaging (MRI) or positron emission tomography-computed tomography (PET-CT). The electroencephalogram (EEG) incuding video electroencephalogram (VEEG) and sleep electroencephalogram (SEEG).

Intervention type: OTHER
Intervention: Multi-modal brain image and EEG
Description: Multi-modal brain image include brain magnetic resonance imaging (MRI) or positron emission tomography-computed tomography (PET-CT). The electroencephalogram (EEG) incuding video electroencephalogram (VEEG) and sleep electroencephalogram (SEEG).

Intervention type: OTHER
Intervention: Omics testing
Description: Omics testing include proteomics, metabolomics, transcriptomics.

Intervention type: OTHER
Intervention: Omics testing
Description: Omics testing include proteomics, metabolomics, transcriptomics.
Study: NCT06204120

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: morphine hydrochloride injection
Description: PCA administration
Study: NCT06220409

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dance classes
Description: A 12-week dance class training program two times a week for 3 months
Study: NCT05480397

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TENS, Distractive techniques, cryotherapy
Description: Group (1): Will receive (TENS , cryotherapy and conventional physical therapy ) Massage with ice was done by the researcher over the AVF puncture site . After that, the TENS electrodes will be applied by the researcher 6 centimeters apart closely up and down the skin area for insertion of the needle.~* Group (2): Will receive (Distraction techniques ,cryotherapy and conventional physical therapy ) Initially five minutes before starting hemodialysis, Distraction techniques will be applied. Natural and eye-catching images were broadcasted through a video display device on a laptop monitor in a manner that was easy for the older patient to watch while they were lying on the bed. Massage with ice was done by the researcher over the AVF puncture site~* Group (3): Will receive (cryotherapy and conventional physical therapy )

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TENS, Distractive techniques, cryotherapy
Description: Group (1): Will receive (TENS , cryotherapy and conventional physical therapy ) Massage with ice was done by the researcher over the AVF puncture site . After that, the TENS electrodes will be applied by the researcher 6 centimeters apart closely up and down the skin area for insertion of the needle.~* Group (2): Will receive (Distraction techniques ,cryotherapy and conventional physical therapy ) Initially five minutes before starting hemodialysis, Distraction techniques will be applied. Natural and eye-catching images were broadcasted through a video display device on a laptop monitor in a manner that was easy for the older patient to watch while they were lying on the bed. Massage with ice was done by the researcher over the AVF puncture site~* Group (3): Will receive (cryotherapy and conventional physical therapy )

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TENS, Distractive techniques, cryotherapy
Description: Group (1): Will receive (TENS , cryotherapy and conventional physical therapy ) Massage with ice was done by the researcher over the AVF puncture site . After that, the TENS electrodes will be applied by the researcher 6 centimeters apart closely up and down the skin area for insertion of the needle.~* Group (2): Will receive (Distraction techniques ,cryotherapy and conventional physical therapy ) Initially five minutes before starting hemodialysis, Distraction techniques will be applied. Natural and eye-catching images were broadcasted through a video display device on a laptop monitor in a manner that was easy for the older patient to watch while they were lying on the bed. Massage with ice was done by the researcher over the AVF puncture site~* Group (3): Will receive (cryotherapy and conventional physical therapy )
Study: NCT06545123

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent exercise training
Description: The experimental groups (AER, RES and AER+RES) will be enrolled in a supervised center-based exercise program for 12 weeks (3 days/week; 60 min/d). Sessions will occur in the morning, on alternating days of the week, and will be supervised by experienced exercise physiologists

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent exercise training
Description: The experimental groups (AER, RES and AER+RES) will be enrolled in a supervised center-based exercise program for 12 weeks (3 days/week; 60 min/d). Sessions will occur in the morning, on alternating days of the week, and will be supervised by experienced exercise physiologists

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent exercise training
Description: The experimental groups (AER, RES and AER+RES) will be enrolled in a supervised center-based exercise program for 12 weeks (3 days/week; 60 min/d). Sessions will occur in the morning, on alternating days of the week, and will be supervised by experienced exercise physiologists
Study: NCT05015556

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Minimal invasive volar plating
Description: Muscle sparing osteosynthesis, no casting postoperatively
Study: NCT06544876

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: sit-to-stand
Description: test for balance during movement from sitting to standing

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: sit-to-stand
Description: test for balance during movement from sitting to standing

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sit-to-stand
Description: test for balance during movement from sitting to standing

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: stand to sit
Description: test for balance during movement from standing to sitting

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: stand to sit
Description: test for balance during movement from standing to sitting

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: stand to sit
Description: test for balance during movement from standing to sitting

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: standing perturbation
Description: test for balance recovery following perturbation

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: standing perturbation
Description: test for balance recovery following perturbation

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: standing perturbation
Description: test for balance recovery following perturbation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MRI of sciatic nerve
Description: measure of peripheral nerve diameter

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MRI of sciatic nerve
Description: measure of peripheral nerve diameter

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MRI of sciatic nerve
Description: measure of peripheral nerve diameter
Study: NCT05679765

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Greater Occipital Nerve Block with dexamethasone and lidocaine
Description: Ultrasound guided Greater occipital nerve block on the side of headache

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Greater Occipital Nerve Block with dexamethasone and lidocaine
Description: Ultrasound guided Greater occipital nerve block on the side of headache

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Greater Occipital Nerve Block with 0.9% saline
Description: Ultrasound guided Greater occipital nerve block on the side of headache

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Greater Occipital Nerve Block with 0.9% saline
Description: Ultrasound guided Greater occipital nerve block on the side of headache
Study: NCT05908747

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: surufatinib + gemcitabine + nab-paclitaxel
Description: surufatinib: 250mg, QD po; nab-paclitaxel: 125mg/m2, I.V., D1/8/15, Q4W; gemcitabine: 1000/m2, ivgtt for more than 30min, D1/8/15, Q4W
Study: NCT05775926

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: Nursing Care and Challenges Training for Nurses Caring for Dying Cancer Patients and Their Families was given in 4 modules and 2 days.
Study: NCT05271682

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FHND6091
Description: FHND6091 capsules
Study: NCT06035939

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Voice Crisis Alert V2
Description: The mHealth self-management intervention consists of the following components: 1) condition-specific electronic educational materials; 2) pain/symptom monitoring and tracking; 3) health history information documentation; 4) medication tracking; 5) secure messaging with a provider; 6) functioning monitoring and tracking; and 7) transmission of health information (graphs with recorded pain and functioning histories) to a provider.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Electronic educational materials
Description: The control arm will receive enhanced usual care, which will consist of usual educational materials distributed at the clinic plus a version of the intervention (Voice Crisis Alert V2) that only includes the electronic educational materials.
Study: NCT05760300

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bulevirtide (BLV)
Description: Administered via subcutaneous (SC) injections

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bulevirtide (BLV)
Description: Administered via subcutaneous (SC) injections
Study: NCT05335915

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Nicotine pouches will be self-administered

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Nicotine pouches will be self-administered

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Nicotine pouches will be self-administered

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Nicotine pouches will be self-administered

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Nicotine pouches will be self-administered

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Nicotine pouches will be self-administered

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cigarette
Description: Cigarette will be smoked
Study: NCT06498687

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CYR-064
Description: Theophylline Nasal Spray
Study: NCT05641662

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heart Farming
Description: Heart Farming is a mobile game. which can be played indoors and outdoors and stimulates players to be physically active. The game is built around a theme (farming) and users are challenged to collect products by being active. The phone will register movements and convert them into points and fruits and vegetables. For the basic playing only 10 minutes walking a day with the game is possible and is rewarded. For players who want more challenge and level of trading products and collecting products in groups is added. The game is adaptable to different levels of mobility and players can invite others to play with them. Players can see their own game results, progression, and active time.
Study: NCT05212480

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Zinc
Description: For each patient included, a prescription regimen of zinc (in bisglycinate form) is proposed at a dose of 25 mgtwice a day for 15 days for the intervention arm. This dose of zinc is to be taken away from meals.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: For each patient included, a prescription of an identical to the intervention arm concerning shape, smell, taste and color pill of placebo . This dose of zinc is to be taken away from meals.
Study: NCT05477628

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Childcare Navigator
Description: Participants will be contacted by the CN to assist with access to centre-based childcare after enrolment. The CN will: a) educate the family on the benefits of centre based childcare; b) facilitate placement of the child on waiting lists for funding and centre based childcare placement in their neighbourhood with the aim of having full-time centre based childcare start at 1 year of age; and c) work with the family to overcome barriers to childcare placement prior to and during childcare. It is expected that the child will be in full-time centre-based childcare for a minimum of 12 months.~Control: All children randomized to the control condition will receive age-appropriate nutritional recommendations as part of routine healthcare according to the Rourke Baby Record.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lactation Consultant
Description: Participants will be contacted by the LC on the same day as their first primary healthcare visit. They will also receive age-appropriate nutrition recommendations according to the Rourke Baby Record. The LC will be an International Board Certified Lactation Consultant (IBCLC) who will provide scheduled and on-call visits, along with phone calls, video conferencing, and text messaging as needed to support exclusive breastfeeding (using virtual care modalities as appropriate during COVID-19). The LC will contact the family once per week for the first 4 weeks to support breastfeeding technique and help with breastfeeding problems such as latching difficulties, painful nursing, and low milk production, monthly thereafter and provide on-call support as required to support exclusive breastfeeding through 6 months of age.~Control: All children randomized to the control condition will receive age-appropriate nutritional recommendations as part of routine healthcare.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lactation Consultant Support and Childcare Navigator Support
Description: This intervention is a combination of the two interventions described above.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control Group
Description: All children randomized to the control condition will receive age-appropriate nutritional recommendations as part of routine healthcare.
Study: NCT06174818

Intervention type: PROCEDURE
Intervention: PRF
Description: Pulsed Radiofrequency Current of the Gasserian Ganglion
Study: NCT06147752

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mobile internet healthcare and co-management of three disciplines
Description: co-management of three disciplines:~Endocrinologist:~Assess disease status and rule out secondary obesity; Identify the causes of overweight/obesity and the status and extent of associated diseases; receive patients for return visits. Timely reply to patients' questions on the mobile medical platform, and timely adjust medication plans according to changes in patients' conditions.~Dietitians:~Conduct diet assessment, develop personalized medicine nutrition treatment plan and provide daily real-time guidance and follow up patients' daily diet outside the hospital.~Weight managers:~Establish weight loss record for patients, guide the installation and use of mobile medical Application , including weight monitoring, real-time uploading of daily diet and online interactive consultation; Follow up patients' weight changes; Assist patients in making appointments for follow-up visits.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mobile internet healthcare and co-management of three disciplines
Description: co-management of three disciplines:~Endocrinologist:~Assess disease status and rule out secondary obesity; Identify the causes of overweight/obesity and the status and extent of associated diseases; receive patients for return visits. Timely reply to patients' questions on the mobile medical platform, and timely adjust medication plans according to changes in patients' conditions.~Dietitians:~Conduct diet assessment, develop personalized medicine nutrition treatment plan and provide daily real-time guidance and follow up patients' daily diet outside the hospital.~Weight managers:~Establish weight loss record for patients, guide the installation and use of mobile medical Application , including weight monitoring, real-time uploading of daily diet and online interactive consultation; Follow up patients' weight changes; Assist patients in making appointments for follow-up visits.
Study: NCT06444711

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: NICE guidance
Description: Patients will be assessed to determine whether their current treatment is in line with NICE guidelines. Changes will be made to their treatment plan in order for them to comply with NICE guidelines with the aim of reducing the number of serious adverse events in the group. They will be followed up until 6 months to identify improvements in their conditions
Study: NCT05432219

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endoscopic surgery
Description: endoscopic resection of recurrent nasopharyngeal carcinoma via the transoral retropterygoid nasopharyngectomy approach
Study: NCT05415241

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FB2001
Description: Stage 1 (Exploring the dose): Twenty participants will be enrolled for aerosol inhalation of FB2001 once daily for 5 consecutive days. If the drug is well tolerated but efficacy is inadequate, another twenty participants will be enrolled for aerosol inhalation of FB2001 BID for 5 consecutive days.~Stage 2 (Sample size expansion): Another twenty participants will be enrolled for aerosol inhalation of FB2001 once daily or twice daily for 5 consecutive days depending on the result of stage 1.
Study: NCT05262166

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INTRATHECAL dexmedetomidine INJECTION
Description: intrathecal bolus of 3ml bupivacaine 0.5% (15mg) plus 10 micrograms dexmedetomidine at 2-3 or 3-4 spinal level.