TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05391555

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pupillometry measurement
Description: The pupil will be examined with the pupillometer at regular intervals, before during and after the opioid infusion
Study: NCT05382156

Intervention type: DRUG
Intervention: Osilodrostat
Description: oral administration of Osilodrostat tablets at different doses according to patient's need
Study: NCT05092750

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FerroTraceTM
Description: A magnetic

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: indocyanine green (ICG)
Description: Given by SC injection
Study: NCT06276530

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: EOS imaging for musculoskeletal disorder
Description: The patients will have a low radiation 2D/3D biplane imaging of the rib cage, and spine before and after surgery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: EOS imaging for musculoskeletal disorder
Description: The patients will have a low radiation 2D/3D biplane imaging of the rib cage, and spine before and after surgery.
Study: NCT05683366

Intervention type: DEVICE
Intervention: No Intervention
Description: There is no intervention in this study
Study: NCT05277870

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nanodropper adaptor
Description: Patients will use their standard prescription for open-angle glaucoma or ocular hypertension with a Nanodropper attachment on the medication bottle.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: Patients will use their prescribed IOP-lowering medication using standard eyedropper on the medication bottle.
Study: NCT04759014

Intervention type: OTHER
Intervention: The effect of using two different prosthetic feet on functional capacity, pain severity, satisfaction level and quality of life
Description: The effect of using two different prosthetic feet on functional capacity, pain severity, satisfaction level and quality of life

Intervention type: OTHER
Intervention: The effect of using two different prosthetic feet on functional capacity, pain severity, satisfaction level and quality of life
Description: The effect of using two different prosthetic feet on functional capacity, pain severity, satisfaction level and quality of life
Study: NCT05929144

Intervention type: OTHER
Group type: OTHER
Intervention: MRI sequences testing
Description: Testing different MRI sequences in order to optimize them
Study: NCT06186882

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Action Video-Game
Description: Thanks to their specific characteristics (presentation of multiple peripheral, rapidly moving, spatio-temporally unpredictable stimuli), Action Video-Games improve reading skills through their effects on the Magnocellular-Dorsal stream. Training will consist of 20 days of Action Video-Games sessions of 1 hour each, three times per week.
Study: NCT05395832

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TAU + multicomponent treatment VIRTUAL FIBROWALK + 4 face-to-face sessions at sea
Description: Group treatment protocol of 12 weekly 60 minute virtual sessions. All sessions include the following ingredients (approx. in the same order):~Pain neuroscience education (15 min.) Cognitive restructuring (15 min.) Mindfulness techniques (15 min.) Physical exercise(15 min.) Treatment as Usual (TAU) 4 face-to-face sessions (1 per mounth) at sea Standard pharmacological treatment usually provided to patients with fibromyalgia.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: TAU + multicomponent treatment VIRTUAL FIBROWALK + 4 face-to-face sessions in nature
Description: Group treatment protocol of 12 weekly 60 minute virtual sessions. All sessions include the following ingredients (approx. in the same order):~Pain neuroscience education (15 min.) Cognitive restructuring (15 min.) Mindfulness techniques (15 min.) Physical exercise(15 min.) Treatment as Usual (TAU) 4 face-to-face sessions (1 per mounth) in nature Standard pharmacological treatment usually provided to patients with fibromyalgia.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: TAU + multicomponent treatment VIRTUAL FIBROWALK
Description: Group treatment protocol of 12 weekly 60 minute virtual sessions. All sessions include the following ingredients (approx. in the same order):~Pain neuroscience education (15 min.) Cognitive restructuring (15 min.) Mindfulness techniques (15 min.) Physical exercise(15 min.) Treatment as Usual (TAU) Standard pharmacological treatment usually provided to patients with fibromyalgia.
Study: NCT04662840

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Geniculate artery embolization
Description: Under fluoroscopic guidance and angiographic imaging, a microcatheter is used to select all the arteries feeding the affected knee and Embosphere (100-300um) particles are injected to obtaining pruning of the hypervascular tissues arteries.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Geniculate nerve ablation
Description: Under fluoroscopic guidance, a Cool-tip RFA ablation needle is advanced such that it touches the femur at the condylar convexity on each side and the tibia at the tibial plateau convexity on the medial side. The ablation is performed to obtain an approximate zone of ablation of 2cm.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Skin infiltration of local anesthetic at groin and knee
Description: Freezing of the skin will be performed at the groin (as prior to an arterial access for embolization procedure) and at three areas around the knee (as prior to insertion of the ablation needles for nerve ablation procedure).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Skin infiltration of local anesthetic at groin and knee
Description: Freezing of the skin will be performed at the groin (as prior to an arterial access for embolization procedure) and at three areas around the knee (as prior to insertion of the ablation needles for nerve ablation procedure).

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Skin infiltration of local anesthetic at groin and knee
Description: Freezing of the skin will be performed at the groin (as prior to an arterial access for embolization procedure) and at three areas around the knee (as prior to insertion of the ablation needles for nerve ablation procedure).
Study: NCT05189340

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Videos
Description: Series of six videos each covering a specific aspect of post-transplant care related to medication use or monitoring
Study: NCT05714358

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: * The patients were given face-to-face training on nutrition, physical activity and drug use in chronic renal failure .~* After the training, the biochemical parameters of the patients were followed for 6 months.~* In this process, the questions asked by the patients in order not to hinder their right to receive information were answered.
Study: NCT05518734

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-708
Description: Solution for intravenous (IV) administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-708
Description: Solution for intravenous (IV) administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-708
Description: Solution for intravenous (IV) administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Solution for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Solution for oral administration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo matched to VX-708 for IV administration.
Study: NCT06276530

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Movement analysis by an optoelectronic camera.
Description: Movement analysis by an optoelectronic camera before and after surgery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Movement analysis by an optoelectronic camera.
Description: Movement analysis by an optoelectronic camera before and after surgery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stabilometric measurement by strength platform
Description: Stabilometric measurement by strength platform before and after surgery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stabilometric measurement by strength platform
Description: Stabilometric measurement by strength platform before and after surgery.
Study: NCT05945667

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Monural
Description: 1 sachet, only 1st day of trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monural
Description: 1 sachet, only 1st day of trial

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: UroNext
Description: 1 sachet per day for the first 7 days, followed by 7 days break Same scheme to be repeated for 3 months
Study: NCT05343221

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Fidelity Simulator
Description: First of all, students will be given 1 hour of CPR training. Then they will be asked to apply with the High Fidelity CPR Simulator. This simulator is adult human sized and specialized for CPR practice. It will not be interfered during the application. The student's practice will be evaluated by an observer. The student will evaluate his/her satisfaction after the application is over.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Haptic
Description: First of all, students will be given 1 hour of CPR training. Then they will be asked to apply with the 3D technology Haptic Device Simulator. This tool has a computer screen and a swing haptic pen. It will not be interfered during the application. The student's practice will be evaluated by an observer. The student will evaluate his/her satisfaction after the application is over.
Study: NCT04726189

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard exercises
Description: Consists of a a standard exercise program with range of motion exercises from the third week and elastic band exercise from the sixth week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard exercises plus Early progressive exercises
Description: This exercise program consists of standard exercises plus the early progressive program that initiates early (second week) and continues with resistance exercises with progression of the load according to individual participant toleration. Exercises are isometric exercises from the second week and then gradually progression of load in seated heel-rise and resistance band exercises.
Study: NCT06126861

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]LP-168
Description: single dose of 150 mg/100 μCi \[14C\] LP-168, orally suspension at fasted state
Study: NCT05652322

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furosemide Pill 150% equivalent iv dose
Description: change from intravenous to oral furosemide

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furosemide Pill 200% equivalent iv dose
Description: change from intravenous to oral furosemide

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Furosemide Injection
Description: change from intravenous to oral furosemide
Study: NCT06406322

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PFMT
Description: Pelvic floor muscle training will be given to patients with strengthening and endurance exercises for 8 weeks. PFMT will be applied at a patient-specific progression for 8 weeks.Exercises will be given in different positions (supine, sitting, etc.).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PFMT
Description: Pelvic floor muscle training will be given to patients with strengthening and endurance exercises for 8 weeks. PFMT will be applied at a patient-specific progression for 8 weeks.Exercises will be given in different positions (supine, sitting, etc.).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise
Description: Aerobic exercise will be applied as a progressive program in the form of a walking program, at least 4 days a week for 8 weeks. There will be 5-minute warm-up and cool-down periods (walking at a light pace) before and after exercise.
Study: NCT06412926

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY 44-4400
Description: Film-coated tablet, oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY 44-4400
Description: Film-coated tablet, oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY 44-4400
Description: Film-coated tablet, oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY 44-4400
Description: Film-coated tablet, oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY 44-4400
Description: Film-coated tablet, oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY 44-4400
Description: Film-coated tablet, oral use
Study: NCT06486220

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intestinal bacteria freeze-dried powder capsules
Description: Oral healthy intestinal bacteria freeze-dried powder capsules, tid
Study: NCT04415333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Butyrate 5 mmol
Description: Enema-based delivery of 5 mmol butyrate in 0.9% saline, (60 mL total)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Butyrate 5 mmol
Description: Enema-based delivery of 5 mmol butyrate in 0.9% saline, (60 mL total)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Butyrate 80 mmol
Description: Enema-based delivery of 80 mmol butyrate in 0.9% saline, (60 mL total)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Butyrate 80 mmol
Description: Enema-based delivery of 80 mmol butyrate in 0.9% saline, (60 mL total)
Study: NCT06264648

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pressure sensitivity education
Description: Therapists were asked to apply pressure to the scale with estimated weights of 0.5 kg, 1 kg, 2 kg and 4 kg. In each measurement, the value shown on the scale was recorded without being shown to the participant.After the measurements, the participants were made to experiment when the digital screen can be seen, in order to teach the physiotherapists how much pressure they applied to reach the target weight. Participants were given a total of 10 minutes for the trials. Then, the digital screen was hidden again, and the therapist was asked to apply 0.5 kg, 1 kg, 2 kg and 4 kg weight in a randomized order and maintain this pressure for 5 seconds. The weight fixed by the therapist for 5 seconds was noted by the researcher; the participant was not informed about the values on the digital screen.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pressure sensitivity education
Description: Therapists were asked to apply pressure to the scale with estimated weights of 0.5 kg, 1 kg, 2 kg and 4 kg. In each measurement, the value shown on the scale was recorded without being shown to the participant.After the measurements, the participants were made to experiment when the digital screen can be seen, in order to teach the physiotherapists how much pressure they applied to reach the target weight. Participants were given a total of 10 minutes for the trials. Then, the digital screen was hidden again, and the therapist was asked to apply 0.5 kg, 1 kg, 2 kg and 4 kg weight in a randomized order and maintain this pressure for 5 seconds. The weight fixed by the therapist for 5 seconds was noted by the researcher; the participant was not informed about the values on the digital screen.
Study: NCT04910919

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Honey
Description: Participants 51 - 100 will receive the standard of care treatment as usual plus 1 tsp of honey with every dose of acetaminophen.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: The first 50 participants will receive treatment as usual (alternating weight-based dosing of acetaminophen and ibuprofen with a PRN three-day supply of opioid analgesic).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: The first 50 participants will receive treatment as usual (alternating weight-based dosing of acetaminophen and ibuprofen with a PRN three-day supply of opioid analgesic).
Study: NCT05922124

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cefiderocol
Description: Test drug regimen

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ampicillin-sulbactam
Description: Synergistic combination

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colistin
Description: Historical comparator
Study: NCT04610034

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resilient Caregivers
Description: Resilient Caregivers is a 7-session group program developed for partner caregivers of patients with cancer (6 weekly sessions and 1 booster session). Each session takes place in groups of approximately 8 participants and lasts for two-and-a-half hours. Sessions 1 to 3 focuses on the caregiver and introduces the resilience components of coping strategies, meta-reflective skill and clarification of values. Sessions 4 and 5 focuses on these components in the relationship between the caregiver and the cancer patient and social support networks respectively, while Session 6 focuses on resilience in relation to self-care and care for the partner. A booster session will be scheduled one month after the end of Session 6 in order to follow-up on the intervention and allow participants to reflect on the benefits and challenges of the program.

Intervention type: OTHER
Group type: OTHER
Intervention: Care as usual
Description: The control arm will receive usual care, which implies no systematic support.
Study: NCT05922124

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Meropenem
Description: Historical comparator synergistic combination
Study: NCT05220228

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prucalopride
Description: 1mg prucalopride x 2d, 2mg prucalopride x 5-8d

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Lactose / sucrose placebo
Study: NCT06064708

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based intervention
Description: The experimental group received 30 minutes of MBI according to Smith's (2005) MBI protocol, which is a standardized theory-based intervention.~Smith's (2005) MBI protocol comprises six components:~1. Being mindful of the breath (5 minutes).~2. Being mindful of the body (5 minutes).~3. Being mindful of the thought (5 minutes)~4. Being mindful of the sound (5 minutes)~5. Being mindful during walking (5 minutes)~6. Full meditation (5 minutes).
Study: NCT04606069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Regadenoson
Description: Regadenoson will be given intravenously as 5 ug/kg (up to 400 mg/patient) loading dose over 30 mins (to avoid unpleasant side effects sometimes associated with the rapid bolus injection of Regadenoson), followed by a continuous slow infusion (1.44micrograms/kg/hour) with the use of a pediatric infusion pump for 6 hours.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control
Description: The same volume of saline will be given intravenously for 6 and half hours.
Study: NCT05359913

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cervical cancer podcast for African American women
Description: The video podcast will deliver cervical cancer prevention messages using entertainment education and behavioral journalism, and film production techniques such as talking head video, interview, animations, \& live-action skits. The research team will work closely with the production company in scripting the video vignettes and sequences, ensuring that video content reflects salient domains captured in the concept mapping research development phase of the study.
Study: NCT05829096

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The COMBINED approach
Description: 1. Patient-level intervention:~   * Assessment of existing lifestyle factors (smoking status, physical activity levels, and weight) that may be relevant to shoulder pain;~  * Brief intervention to support health behaviour change: smoking cessation, increasing physical activity levels and consuming a healthy diet~  * Supporting tools for behaviour change, including an activity workbook for goal-setting and a diary for self-monitoring.~2. Clinician-level implementation toolkit:~   * Training package including a face-to-face workshop, training manual, recorded role play simulations and an online follow-up training session~  * Additional supporting resources; a step-by-step guide to The COMBINED approach, scripts, patient signposting information to support services and a lay summary infographic to explain the links between the health behaviours and RC disorders to patients~  * Audit and feedback via observations of consultations to address any 'drift' from the intervention delivery as intended
Study: NCT05271084

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Citalopram (tablet) 20 mg + Pentoxifylline (tablet) 400Mg
Description: Selective serotonin reuptake inhibitor (SSRI) + phosphodiesterase inhibitor with anti-inflammatory properties

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Citalopram (tablet) 20 mg + Placebo (tablet)
Description: Selective serotonin reuptake inhibitor (SSRI) + placebo
Study: NCT05271019

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Threshold load device
Description: Inspiratory Muscle Training (IMT) for 3 months:~Though a threshold loading device (5 sets of 6 repetitions, 1session/day, 5 days/week). the inspiratory load will start at 30% of MIP, or up to the maximum patient-tolerable load (max 60% of MIP), no more than 3-5/10 on the modified Borg scale.
Study: NCT06317233

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chronic Pelvic Pain Treatment Guide
Description: The treatment guide includes mobile and web-based resources and applications specifically chosen to empower patients with information and to promote self-efficacy. The treatment guide is designed to be easily understood, visually appealing, and largely translatable from institution to institution. Patients using the treatment guide will be followed with a clearly defined follow up schedule, which includes touch points between appointments to aid with resource navigation.
Study: NCT05728086

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group art therapy
Description: The intervention is a manualised programme of group art therapy based on a bio-psychosocial therapeutic model. The programme is made up of six 60 - 90-minute art therapy group sessions facilitated by an experienced HCPC (Health and Care Professions Council) registered Art Therapists trained in the intervention.
Study: NCT05142514

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 Vaccine HIPRA
Description: Subjects will receive 2 injections of COVID-19 vaccine HIPRA administered 21 days apart

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Cominarty (Pfizer-BioNtech)
Description: Subjects will receive 2 injections of Cominarty administered 21 days apart