TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06657976

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supervised Treadmill Exercise
Description: This is a 12 week intervention where participants will walk for exercise 3 times a week on a treadmill at a center while being supervised by healthcare personnel.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Attention Control
Description: This group will attend weekly one-hour educational sessions either on Zoom or in-person for 12 weeks. These sessions are on topics of interest to the typical PAD patient and may be led by study staff, physicians, or other health care workers.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nitrate-Rich Beetroot Juice + supervised exercise therapy
Description: Participants randomized to this group will drink nitrate-rich beetroot juice while engaged in supervised exercise.

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo + supervised exercise therapy
Description: Participants randomized to this group will drink placebo while engaged in supervised exercise.
Study: NCT06664034

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-component reproductive health care intervention
Description: The multi-component reproductive health care intervention includes:~1. Young cancer patients presenting to oncology visits will complete a clinic-based reproductive health needs screen with a member of the clinical team. This needs screen assesses i) desire to have a child in the future and ii) need for contraception.~2. Reproductive health patient navigation consists of one telehealth or in-person session with a social worker to: i) assess the patient's reproductive health needs, ii) provide individualized patient education and counseling on a) infertility risk related to cancer type and treatment and b) screening and management strategies for reproductive health needs, iii) provide support with the goal of engaging in goal-concordant reproductive health care.~3. Telehealth reproductive health consultation will occur between the patient and reproductive specialist. Each consultation is estimated to be 1 hour.
Study: NCT06666218

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Intervention
Description: Complete the HOPE intervention workshop

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Intervention
Description: Complete the HOPE intervention workshop

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electronic Health Record Review
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Complete an interview

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Complete a survey

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies
Study: NCT06604715

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-87562761
Description: JNJ-87562761 will be administered.
Study: NCT05619432

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HMD: Immersive VR
Description: The device application involves the 3D multiple-object-tracking (3D-MOT) paradigm composed of 8 high-contrast spheres which are adapted to the visual ability of participant (luminosity and size). The initial speed of the spheres is adjustable and determined during the inclusion visit.~STIMULATION:~One or more of the spheres is temporarily cued (target). Then all spheres move for 20 seconds following random linear paths, bouncing on one another and on the walls of a virtual 3D cube when collisions occur. After 20 seconds, the movement stops and the participant is asked to select, using a laser pointer, the initially cued target(s) among the eight spheres. If the selection is correct the speed of the spheres in the next trial is increased. If the selection is incorrect the speed of the spheres in the next trial is decreased.~Based on performance, stimulations will be adjusted to change difficulty level (e.g. changing backgrounds, number of cued balls, etc.)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HMD: Immersive VR
Description: The device application involves the 3D multiple-object-tracking (3D-MOT) paradigm composed of 8 high-contrast spheres which are adapted to the visual ability of participant (luminosity and size). The initial speed of the spheres is adjustable and determined during the inclusion visit.~STIMULATION:~One or more of the spheres is temporarily cued (target). Then all spheres move for 20 seconds following random linear paths, bouncing on one another and on the walls of a virtual 3D cube when collisions occur. After 20 seconds, the movement stops and the participant is asked to select, using a laser pointer, the initially cued target(s) among the eight spheres. If the selection is correct the speed of the spheres in the next trial is increased. If the selection is incorrect the speed of the spheres in the next trial is decreased.~Based on performance, stimulations will be adjusted to change difficulty level (e.g. changing backgrounds, number of cued balls, etc.)
Study: NCT06609109

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC High Dose
Description: Low dose of THC (30 mg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC High Dose
Description: Low dose of THC (30 mg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC Low Dose
Description: Low dose of THC (5 mg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC Low Dose
Description: Low dose of THC (5 mg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC 0mg
Description: Placebo dose of THC (0 mg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC 0mg
Description: Placebo dose of THC (0 mg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E-Cigarette Full Nicotine
Description: E-Cigarette with Nicotine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E-Cigarette Full Nicotine
Description: E-Cigarette with Nicotine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E-Cigarette Placebo Nicotine
Description: E-Cigarette with No Nicotine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E-Cigarette Placebo Nicotine
Description: E-Cigarette with No Nicotine
Study: NCT06662188

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: JAG201
Description: Adeno-associated virus 2/9 expressing a miniature version of the human SHANK3 gene (AAV2/9-miniSHANK3)

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: JAG201
Description: Adeno-associated virus 2/9 expressing a miniature version of the human SHANK3 gene (AAV2/9-miniSHANK3)
Study: NCT05202106

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home visits
Description: Home visits entail a visit a children's home every two weeks. During this visit, trained child development agents will engage parents in activities with the child and provide basic toys and learning materials.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Afini App
Description: Afini is an app designed to help parents provide nurturing environments and stimulation to their young children. Most caregivers currently connect to the platform via Facebook Messenger; once they sign up, the platforms start engaging the caregiver by recommending age-specific health- and development-promoting activities. Rather than just hoping that caregivers will later engage in these activities, the virtual assistant directly observes whether caregivers access the materials for the recommended activity, and asks caregivers to provide feedback on each task.
Study: NCT04760691

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Truvada alone
Description: TDF/FTC 300 mg (milligrams) / 200 mg by mouth once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Truvada plus Leuprolide
Description: TDF/FTC 300mg/ 200 mg by mouth once daily Leuprolide 11.25 mg im once

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Truvada plus Estradiol 1 mg
Description: TDF/FTC 300mg/ 200 mg by mouth once daily Estradiol 1 mg by mouth once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Truvada plus Estradiol 6 mg
Description: TDF/FTC 300mg/ 200 mg by mouth once daily Estradiol 3 mg by mouth twie daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Estradiol 6 mg alone
Description: Estradiol 3 mg by mouth twice daily
Study: NCT06612866

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Keratin hydrolysate
Description: The clinical study will be conducted in two phases. The first phase will aim at characterizing the metabolites present in human serum after consumption of the Kera-Diet® ingredient and at determining the overall absorption peak of the tested ingredient. The second phase will involve collecting sera enriched with metabolites at the absorption peak, following the ingestion of the ingredient. Subsequently, the final objective will be to characterize the influence of these sera enriched with metabolites of interest on the behavior of human skin cell and intestinal epithelial cell cultures.
Study: NCT06614504

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of cigarettes
Description: Altering the nicotine content of the tobacco research cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of cigarettes
Description: Altering the nicotine content of the tobacco research cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of cigarettes
Description: Altering the nicotine content of the tobacco research cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of cigarettes
Description: Altering the nicotine content of the tobacco research cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of e-cigarettes
Description: Altering the nicotine content of the research e-cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of e-cigarettes
Description: Altering the nicotine content of the research e-cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of e-cigarettes
Description: Altering the nicotine content of the research e-cigarettes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Varying the nicotine content of e-cigarettes
Description: Altering the nicotine content of the research e-cigarettes
Study: NCT06400719

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AVT16
Description: Single intravenous administration of 300mg of AVT16
Study: NCT06616155

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tissue biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Scan
Description: Undergo bone scan

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enzalutamide
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Given PO
Study: NCT00733915

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: L.C.S. Complete Knee (DePuy Low Contact Stress Complete Knee System)
Description: L.C.S. Complete mobile-bearing total knee system
Study: NCT06608511

Intervention type: OTHER
Intervention: Blood draw for the laboratory assessment
Description: Participants will have 50 milliliters (3.5 tablespoons) of blood drawn
Study: NCT06616844

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: InnovaMatrix® AC
Description: SOC plus weekly application of the study device
Study: NCT06619782

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Practice Facilitation
Description: Practice facilitation (PF) is a supplemental support to increase competence and and adoption of the National Institute of Mental Health (NIMH) youth suicide prevention. pathway in primary care. Practices will receive 6 months of PF which involves clinic- and provider- level data review and adoption data for the 5 components of the prevention pathway, clinical coaching around implementing the different components , logistical coaching in identifying multilevel contextual barriers to implementation and strategies to overcome them

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training in National Institute of Mental Health Youth Suicide Prevention Pathway
Description: Training in the National Institute of Mental Health (NIMH) Youth Suicide Prevention Pathway involves a 2-hour in-person presentation created in consultation with NIMH, Zero Suicide and Substance Abuse and Mental Health Services Administration. It is delivered by a licensed professional counselor with content expertise to all primary care practice personnel involved in the prevention pathway. The first hour focuses on conducting Ask Suicide Screening Questions (ASQ) screening, identifying risk/protective factors, identifying warning signs and conducting a brief suicide safety assessment. The second hour covers safety planning, lethal means safety, behavioral health referrals and arranging follow-up. Didactic and interactive methods are used, including group discussion, activities, videos and case vignettes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Training in National Institute of Mental Health Youth Suicide Prevention Pathway
Description: Training in the National Institute of Mental Health (NIMH) Youth Suicide Prevention Pathway involves a 2-hour in-person presentation created in consultation with NIMH, Zero Suicide and Substance Abuse and Mental Health Services Administration. It is delivered by a licensed professional counselor with content expertise to all primary care practice personnel involved in the prevention pathway. The first hour focuses on conducting Ask Suicide Screening Questions (ASQ) screening, identifying risk/protective factors, identifying warning signs and conducting a brief suicide safety assessment. The second hour covers safety planning, lethal means safety, behavioral health referrals and arranging follow-up. Didactic and interactive methods are used, including group discussion, activities, videos and case vignettes
Study: NCT06624982

Intervention type: OTHER
Intervention: observational study
Description: Observational study; alveolar ridge preservation

Intervention type: OTHER
Intervention: observational study
Description: Observational study; alveolar ridge preservation

Intervention type: OTHER
Intervention: observational study
Description: Observational study; alveolar ridge preservation

Intervention type: OTHER
Intervention: observational study
Description: Observational study; alveolar ridge preservation
Study: NCT04850261

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nafarelin nasal spray
Description: Ovulation will be induced by nasal application of Nafarelin
Study: NCT06682702

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DNS Group
Description: ISST Schroth exercises are a model of exercise aimed at correcting scoliosis in three dimensions. Dynamic neuromuscular stabilization exercises, on the other hand, are designed to achieve sagittal stabilization by utilizing the stabilizing function of the thoracic diaphragm muscle.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Schroth Group
Description: ISST Schroth exercises are a model of exercise aimed at correcting scoliosis in three dimensions.
Study: NCT06682143

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality (VR)
Description: Participants will engage in a virtual reality greenspace activity for a period of 5 minutes

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Participants will sit quietly for a period of 5 minutes
Study: NCT06685835

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brensocatib
Description: Film-coated Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brensocatib
Description: Film-coated Oral tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Brensocatib
Description: Film-coated Oral tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Brensocatib
Description: Film-coated Oral tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Film-coated Oral tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Film-coated Oral tablet
Study: NCT05584202

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273.214
Description: Sterile liquid for injection
Study: NCT05591222

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo/Daxdilimab
Description: Placebo/Daxdilimab will be administered subcutaneously as two injections for each dose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daxdilimab
Description: Daxdilimab will be administered subcutaneously as two injections for each dose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daxdilimab
Description: Daxdilimab will be administered subcutaneously as two injections for each dose.
Study: NCT05584202

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273.214
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273.214
Description: Sterile liquid for injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% sodium chloride
Study: NCT06713460

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BEAM
Description: Multicomponent intervention
Study: NCT06748404

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tricalm Hydrogel
Description: TriCalm Hydrogel® is a topical gel that allows rapid administration to areas of the skin. TriCalm Hydrogel® is available over-the-counter and contains the active ingredient, aluminum acetate 0.2%, and inactive ingredient, strontium chloride hexahydrate.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tricalm Hydrogel
Description: TriCalm Hydrogel® is a topical gel that allows rapid administration to areas of the skin. TriCalm Hydrogel® is available over-the-counter and contains the active ingredient, aluminum acetate 0.2%, and inactive ingredient, strontium chloride hexahydrate.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triamcinolone acetonide 0.1% cream
Description: Triamcinolone acetonide 0.1% cream is a topical steroid cream that will be applied directly to the skin.
Study: NCT05811351

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-81201887
Description: JNJ-81201887 will be administered as intravitreal injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-81201887
Description: JNJ-81201887 will be administered as intravitreal injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone will be administered as oral capsule.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone will be administered as oral capsule.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Placebo
Description: Prednisone matching placebo will be administered as oral capsule.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone
Description: Triamcinolone (corticosteroid injection) periocular injection will be administered as per local practice.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone
Description: Triamcinolone (corticosteroid injection) periocular injection will be administered as per local practice.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Procedure
Description: Sham injections matching to single JNJ-81201887 injection and matching to corticosteroid (triamcinolone) periocular injection will be administered.
Study: NCT06749496

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test Lens
Description: ACUVUE® OASYS MAX 1-Day for ASTIGMATISM (AOM1DfA).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test Lens
Description: ACUVUE® OASYS MAX 1-Day for ASTIGMATISM (AOM1DfA).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Control Lens
Description: Alcon DAILIES TOTAL1® for Astigmatism Contact Lenses (DT1fA).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Control Lens
Description: Alcon DAILIES TOTAL1® for Astigmatism Contact Lenses (DT1fA).
Study: NCT06748443

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support intervention for the use of Knee Control+
Description: Coaches will be offered a smorgasbord of support interventions that they can choose from depending on their specific needs: physical and digital workshops before and during the study, site visits to their team, digital programme material, leaflets and social media posts. Fitness coaches will be responsible for physical workshops to train the football coaches.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information about Knee Control+
Description: Coaches receive information about injuries in football and the efficacy of injury prevention exercise programmes at a pre-season digital workshop, and guided to access the Knee Control+ programme from the Swedish Football Association website.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Information about Knee Control+
Description: Coaches receive information about injuries in football and the efficacy of injury prevention exercise programmes at a pre-season digital workshop, and guided to access the Knee Control+ programme from the Swedish Football Association website.
Study: NCT06757673

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robot-Assisted Therapy using Kebbi Air
Description: Participants in this group will engage with the Kebbi Air smart robot, which is programmed with interactive scripts designed to enhance social-emotional regulation skills. The intervention includes weekly 30-minute sessions over a 12-week period, where the robot simulates real-life social scenarios and provides verbal and visual responses to guide participants in developing emotional and social skills. Occupational therapists will supervise these sessions to ensure the appropriateness of interactions and provide additional support as needed.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sensory Integration Therapy
Description: Participants in this group will receive traditional sensory integration therapy guided by occupational therapists. The therapy focuses on improving sensory processing and emotional regulation through structured activities targeting visual, auditory, and tactile stimuli. Each session is conducted weekly, lasting 30 minutes, for a total of 12 weeks. The therapy aims to help children adapt to sensory inputs and enhance their ability to engage in social interactions and manage emotions effectively.