TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05345106

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: Subjects with obesity (N=60) will be undertaken a hypocaloric diet and a periodic follow up, also 30 of them will undergo bariatric surgery

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: Subjects with obesity (N=60) will be undertaken a hypocaloric diet and a periodic follow up, also 30 of them will undergo bariatric surgery

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: Subjects with obesity (N=60) will be undertaken a hypocaloric diet and a periodic follow up, also 30 of them will undergo bariatric surgery
Study: NCT06282913

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Meditation
Description: Mindfulness Meditation application will be implemented online by the researcher in 20-minute group sessions once a week for 8 weeks. Participants will be asked to provide a quiet, ventilated, dimly lit environment for the practice. The researcher will start the application when the participants take their places as they feel comfortable. In the first stage, the researcher will teach physicians and nurses to take deep diaphragmatic breaths through the nose and out through the mouth.
Study: NCT05751720

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GIP/GLP-1a
Description: The group will receive GLP-1 analogues (subcutaneous Tirzepatide). The dose of Tirzepatide is 0.25 mg once weekly for 4 weeks then 0.5 mg once weekly.
Study: NCT05829434

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Patients will receive magrolimab on day 1; 4: IV 1 mg/kg; day 8: IV 15 mg/kg; day 11, 15 and 22: IV 30 mg/kg (plus 30 mg/kg for 5 weeks weekly and then q2w until the end of consolidation)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Patients will receive magrolimab on day 1; 4: IV 1 mg/kg; day 8: IV 15 mg/kg; day 11, 15 and 22: IV 30 mg/kg (plus 30 mg/kg for 5 weeks weekly and then q2w until the end of consolidation)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 7+3
Description: Patients will receive during Induction cycle 1: cytarabine at 100 mg/m² on study days 1-7 as a continuous infusion over 22-24 hours and daunorubicin at 60 mg/m² on study days 3, 4, 5~* optional during Induction cycle 2: cytarabine at 100 mg/m² on days 1-7 of the second induction cycle (i.e. study days 29-35) as a continuous infusion over 22-24 hours and daunorubicin at 60 mg/m² on days 3, 4, 5 of the second induction cycle (i.e. study days 31, 32, 33)~* optional during Consolidation cycle: cytarabine at 1 g/m² administered on days 1, 3, 5 of each consolidation cycle as an infusion for 2 hours every 12 hours (for patients \< 60 years up to 3 CONS cycles and for patients ≥ 60 years up to 2 CONS cycles)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CPX-351
Description: Patients will receive during Induction cycle 1: CPX-351 with daunorubicin 44 mg/m² and cytarabine 100 mg/m² on days 1, 3, 5~* optional during Induction cycle 2: CPX-351 with daunorubicin 44 mg/m² and cytarabine 100 mg/m² on days 29 + 30~* optional during Consolidation cycle: CPX-351 with daunorubicin 29 mg/m² and cytarabine 65 mg/m² on days 1, 3
Study: NCT04809415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Photobiomodulation
Description: Photobiomodulation consists of irradiation by light in order to achieve photochemical and photophysical outcomes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Photobiomodulation
Description: Photobiomodulation consists of irradiation by light in order to achieve photochemical and photophysical outcomes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: Simulation of the application of photobiomodulation therapy.
Study: NCT04706026

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Open Inguinal Hernia Repair - Local Anesthesia
Description: Patients in the local anesthesia arm will receive an injection of a 50:50 mix of 1% lidocaine with epinephrine and 0.25% Marcaine at the surgical site (in the skin and subcutaneous layers + beneath the external oblique aponeurosis). Patients in the local arm will also receive intravenous sedation (Propofol or Precedex) and pain medication (morphine or fentanyl) at the discretion of the attending anesthesiologist.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Inguinal Hernia Repair - General Anesthesia
Description: General anesthesia will be administered at the discretion of the anesthesiologist and will involve a combination of inhaled and intravenous anesthesia.
Study: NCT06639711

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Taurine
Description: Taurine-containing eye drops (VIZILOTON) are applied 4 times daily for a period of one year
Study: NCT06641141

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Induction of Labour
Description: Induction of Labour (IOL) will occur between 38+0 weeks and 38+6 weeks. All participating sites will follow an evidence-based approach for IOL, which may include any of the following: use of prostaglandins, oxytocin, amniotomy, or intracervical balloon catheters with and without extra-amniotic saline infusion for the intervention arm. Participants who are induced in either the intervention or control arms will be managed by their delivery care provider to ensure sufficient time to labour and determine when to proceed to Cesarean delivery. What constitutes a failed IOL will be dictated by local clinical practice guidelines and will be informed by the time since IOL (24-48 hours) and/or physician diagnosis of labour dystocia.
Study: NCT06493214

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to complete three eight-minute InPACT at Home exercise videos per day, five days a week, for 12 weeks.
Study: NCT05404685

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low insufflation pressure (7mm Hg) for Robotic Assisted Partial Nephrectomy
Description: Use of insufflation pressure at 7 mm Hg. The groups will differ only with respect to the insufflation pressure level set on the AirSeal® system.~The level of pressure will be adjusted at the beginning of the surgery, after placement of the trocars, in accordance with the result of the randomization.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard insufflation pressure (12mm Hg) for Robotic Assisted Partial Nephrectomy
Description: Use of insufflation pressure at 12 mm Hg. The groups will differ only with respect to the insufflation pressure level set on the AirSeal® system.~The level of pressure will be adjusted at the beginning of the surgery, after placement of the trocars, in accordance with the result of the randomization.
Study: NCT06530797

Intervention type: DRUG
Intervention: First-line Adebrelimab regiment for advanced stage ES-SCLC
Description: First-line Adebrelimab in any regiment for advanced stage ES-SCLC

Intervention type: DRUG
Intervention: Second-line and beyond Adebrelimab regiment for advanced stage ES-SCLC
Description: Second-line and beyond Adebrelimab in any regiment for advanced stage ES-SCLC
Study: NCT05346042

Intervention type: OTHER
Intervention: duration infectiousness
Description: is the probability and the duration of being infectious in hospitalized COVID-19 patients, consequently influencing the decision on cessation of isolation
Study: NCT05446779

Intervention type: DIAGNOSTIC_TEST
Intervention: Adrenal aldosterone synthase (CYP11B2) staining
Description: Immunoshistochemical diagnosis of primary aldosteronism

Intervention type: DIAGNOSTIC_TEST
Intervention: Adrenal aldosterone synthase (CYP11B2) staining
Description: Immunoshistochemical diagnosis of primary aldosteronism

Intervention type: DIAGNOSTIC_TEST
Intervention: Adrenal cortisol synthase (CYP11B1) staining
Description: Immunoshistochemical diagnosis of adrenal hypercortisolism

Intervention type: DIAGNOSTIC_TEST
Intervention: Adrenal cortisol synthase (CYP11B1) staining
Description: Immunoshistochemical diagnosis of adrenal hypercortisolism

Intervention type: DIAGNOSTIC_TEST
Intervention: Histopathological analysis
Description: Diagnosis of any endocrine neoplasia other than primary aldosteronism or adrenal hypercortisolism

Intervention type: DIAGNOSTIC_TEST
Intervention: Histopathological analysis
Description: Diagnosis of any endocrine neoplasia other than primary aldosteronism or adrenal hypercortisolism
Study: NCT06083519

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: White Noise
Description: This is the control condition. Listening to white noise -- participants listen to white noise for 24 minutes

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music and Auditory Beat Stimulation
Description: Listening to music and auditory beat stimulation. The VIBE app (LUCID) incorporates theta-band (4 Hz) auditory beat stimulation and an auditory music recommendation system. Participants will listen to this music with theta auditory beat stimulation for 24 minutes.
Study: NCT06274294

Intervention type: DRUG
Group type: OTHER
Intervention: CT-P13
Description: Induction treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-P13
Description: Induction treatment.
Study: NCT06163248

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chrono nutrition
Description: An integral nutritional strategy involving timing, order and distribution of macronutrients

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard
Description: Conventional nutritional strategy involving isocaloric distribution with no specific timing
Study: NCT05298865

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive imagination stimulation
Description: The intervention messages aim to generate participants' positive mental image toward their life and also to relieve parental stress by shifting their attention to positive life events. The positive affect cues will be developed based on qualitative interviews with 30 parents from our previous study during pandemic and also extended literatures on positive psychology. Our previous qualitative interview aimed to understand parental concerns on flu and COVID-19 vaccination, parental life stressors throughout the pandemic were also explored. The positive cues will be discussed and evaluated by the research team with an aim to cover major positive life events that are personal relevant to parents, including positive social support (friendship), positive family support (family gathering), qualified time spent with children (here we will also embed a gratitude practice to elicit strong positive feelings), and cultivate positive self by imagining achieving personal goals in the future.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Neutral recall message
Description: The control message aims to equate time and attention as in the intervention group. Therefore, a recall task will be assigned to participants. Brief texts will be provided to guide participants to memorize their life senarios but not to induce emotions. Messages include the following: recall the breakfast and lunch you had yesterday; recall the clothes and shoes you wore yesterday; recall the kitchen in your home; recall one of the chairs in your home; recall the routes to the nearest supermarket and subway of your house.
Study: NCT05626842

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Total Diet Replacement (800kcal/day)
Description: The TDR intervention involves a low-calorie, nutritionally complete diet for 12 weeks consuming four meal replacement products exclusively per day, followed by a 4-week food-based reintroduction period; and then weight loss maintenance support monthly for a further 36 weeks. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a TDR for an additional 4 weeks.
Study: NCT05247229

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Middle school education program
Description: The intervention assesses the impact of a middle school education program (implemented as an after school program in Sitka, AK and Juneau, AK and during school hours as an elective in Hoonah, AK) on shellfish and toxin knowledge and clam harvesting planned behaviors. The intervention takes place weekly during the school year. The curriculum centers around teaching children about local traditional ecological knowledge and traditional harvesting and gathering practices.
Study: NCT06272721

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Griffiths Scale
Description: The Griffiths Mental Development Scales II are key tools for assessing children's psychomotor development from ages 0 to 6, praised for their strong psychometric properties. They evaluate various functional areas through six subscales, combining parental reports and direct observations of the child's behavior. The areas include locomotion, personal-social interaction, learning and language, eye-hand coordination, and performance, excluding the optional practical reasoning section for older children in this study. The Development Quotient (DQ), calculated by comparing mental and chronological ages, indicates developmental progress or delay, with an average score around 100 ± 15.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Griffiths Scale
Description: The Griffiths Mental Development Scales II are key tools for assessing children's psychomotor development from ages 0 to 6, praised for their strong psychometric properties. They evaluate various functional areas through six subscales, combining parental reports and direct observations of the child's behavior. The areas include locomotion, personal-social interaction, learning and language, eye-hand coordination, and performance, excluding the optional practical reasoning section for older children in this study. The Development Quotient (DQ), calculated by comparing mental and chronological ages, indicates developmental progress or delay, with an average score around 100 ± 15.
Study: NCT05327933

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery plus endovascular MMA embolization
Description: A micro catheter is inserted transfemorally into the branches of the middle meningeal artery (MMA) in a minimally invasive manner and the periphery is occluded using polyvinyl alcohol (PVA) particles to prevent future bleeding. If the desired catheter position cannot be achieved due to the anatomical conditions, a more proximal closure of the MMA using Onyx® or micro-electric coils is performed. Embolization of the MMA by PVA particles with sizes between 40-300 µm is preferred over embolization by coils and Onyx®, since the capillary network of the dura is entirely blocked when using particles. In order to identify the vessels to be closed, a digital subtraction angiography (DSA) is performed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgery alone
Description: Evacuation of cSDH
Study: NCT05669534

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.
Study: NCT04941508

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: the mother's recorded voice
Description: Children will be assigned to listen to the mother's recorded voice at 2 times (in the holding area 3 minutes before induction of anesthesia till induction of anesthesia is ended) and (during emergence from anesthesia till complete recovery).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Children will be given a single bolus of dexmedetomidine 0.2 µ/kg IV at 2 times (in the holding area 3 minutes before induction of anesthesia) and (at the end of surgery).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: saline 0.9% placebo
Description: Children will be given the same volume of saline at 2 times (in the holding area 3 minutes before induction of anesthesia) and (at the end of surgery).
Study: NCT04913194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ARFID-PTP
Description: ARFID-PTP is a two-session virtual protocol using psychoeducation, parent training skills, and exposure to decrease picky eating symptoms consistent with an ARFID diagnosis.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: ARFID-PTP
Description: ARFID-PTP is a two-session virtual protocol using psychoeducation, parent training skills, and exposure to decrease picky eating symptoms consistent with an ARFID diagnosis.
Study: NCT06250374

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bilateral trans-cranial Doppler ultrasound
Description: Velocity measurements in the middle cerebral artery are made using an ultrasound probe applied to the patient's temple during surgery.
Study: NCT05259605

Intervention type: OTHER
Intervention: Observational
Description: The goal is to determine whether the new 2021 WHO classification, based on cIMPACT-NOW recommendations, results in more homogeneous patient groups than the old 2016 classification. Furthermore, it will help derive provisional guidelines on how patients with these newly defined tumour entities are best treated. These recommendations will be based on the experience of EORTC investigators with chosen treatments and their experience as reported in this data collection report.
Study: NCT05712278

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR445419
Description: Cell suspension, by intraveneous (IV) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fludarabine
Description: Solution for injection , by IV injection
Study: NCT05712278

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cytarabine
Description: Solution for injection, by IV injection
Study: NCT05669534

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: community-friendly health recovery program
Description: Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.
Study: NCT06074354

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attention-control group
Description: Participants will receive a one-hour general health promotion session from a nurse and be issued a phone that will deploy the EMA on the same schedule as the intervention arm. They will also receive usual care from the clinics, drop-in center, and shelter recruitment sites. Usual care includes accessing social workers and case managers for immediate housing, food, and clothing needs and assistance in navigating the local Continuum of Care system to access social services.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MY-RIDE group
Description: MY-RIDE has three main components: 1) One nurse-led face-to-face session; 2) three months of Ecological Momentary Assessments (EMA) with personalized messaging delivered by phone in real-time in response to one's current risk; and 3) access to on-demand healthcare/PrEP navigation and referrals.
Study: NCT05029089

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Modified Entire Papilla Preservation Technique (MEPPT) For Periodontal Regenerative Treatment Of Intrabony Defects.
Description: Surgical approach using modified papilla preservation technique for regenerative periodontal therapy.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Modified Entire Papilla Preservation Technique (MEPPT) For Periodontal Regenerative Treatment Of Intrabony Defects.
Description: Surgical approach using modified papilla preservation technique for regenerative periodontal therapy.