TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05506761

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ultrasound-guided erector spinae plane block
Description: Patients will receive 20 ml plain bupivacaine 0.25 % bolus, then 10 ml per hour plain bupivacaine 0.125 % continuous infusion via ultrasound-guided erector spinae plane block

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ultrasound-guided rhomboid intercostal block combined with sub-serratus plane block
Description: Patients will receive 20 ml plain bupivacaine 0.25 % bolus, then 10 ml per hour plain bupivacaine 0.125 % continuous infusion via ultrasound-guided rhomboid intercostal block combined with sub-serratus plane block
Study: NCT06222125

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HB0025
Description: HB0025 IV every 2 weeks (q2w)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HB0025
Description: HB0025 IV every 2 weeks (q2w)
Study: NCT05206526

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dragon Boat
Description: 12 weeks of training, defined by a precise progressive, structured and supervised program divided into 3 weekly sessions of one hour / one hour and a half preparatory to the Dragon Boat activity.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Home-based Exercise
Description: 12 weeks of home-based training composed by 10 exercises.
Study: NCT04555122

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Distancing Advertisements
Description: Participants will receive 3 types of advertisements to increase social distancing/staying at home.
Study: NCT04951687

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ecologic Barrier©
Description: 5x10\^9 CFU/ 2g per day of Ecologic Barrier©

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo powder
Description: matched placebo
Study: NCT04453293

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BCG (Tokyo 172) vaccine
Description: Freeze-Dried Glutamate Bacillus Calmette-Guérin BCG Vaccine (Japan BCG Laboratory), 0.1 mL given as single dose by intradermal injection over the outer lower aspect of the deltoid region

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo vaccine diluent, 0.1 mL given as single dose by intradermal injection over the outer lower aspect of the deltoid region
Study: NCT05146570

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: D-lactate test
Description: In device-associated meningitis, CSF will be aspirated before, during or after surgery related to the device, according to the standard practice. Lumbar/ventricular punctures (pre-, intra- and/or postoperatively) and external ventricular (EVD) and lumbar drainage (ELD) aspiration will be performed by neurologist or neurosurgeon according to standardized aseptic techniques. In patients with native meningitis, CSF will be aspirated by lumbar puncture, according the standard practice. The D-lactate test will be performed using spectrophotometric enzyme assay according to the manufacturer's instructions (D-Lactate Colorimetric Assay).

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: D-lactate test
Description: In device-associated meningitis, CSF will be aspirated before, during or after surgery related to the device, according to the standard practice. Lumbar/ventricular punctures (pre-, intra- and/or postoperatively) and external ventricular (EVD) and lumbar drainage (ELD) aspiration will be performed by neurologist or neurosurgeon according to standardized aseptic techniques. In patients with native meningitis, CSF will be aspirated by lumbar puncture, according the standard practice. The D-lactate test will be performed using spectrophotometric enzyme assay according to the manufacturer's instructions (D-Lactate Colorimetric Assay).

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Standard diagnostic tests
Description: In device-associated meningitis, CSF will be aspirated before, during or after surgery related to the device, according to the standard practice. Lumbar/ventricular punctures (pre-, intra- and/or postoperatively) and external ventricular (EVD) and lumbar drainage (ELD) aspiration will be performed by neurologist or neurosurgeon according to standardized aseptic techniques. In patients with native meningitis, CSF will be aspirated by lumbar puncture, according the standard practice. The standard diagnostic tests will be performed according to standard diagnostic laboratory instructions.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Standard diagnostic tests
Description: In device-associated meningitis, CSF will be aspirated before, during or after surgery related to the device, according to the standard practice. Lumbar/ventricular punctures (pre-, intra- and/or postoperatively) and external ventricular (EVD) and lumbar drainage (ELD) aspiration will be performed by neurologist or neurosurgeon according to standardized aseptic techniques. In patients with native meningitis, CSF will be aspirated by lumbar puncture, according the standard practice. The standard diagnostic tests will be performed according to standard diagnostic laboratory instructions.
Study: NCT05148975

Intervention type: DIAGNOSTIC_TEST
Intervention: Bronchoalveolar lavage fluid diagnostics
Description: Bronchoalveolar lavage fluid diagnostics for superinfection in patients with COVID-19 pneumonia.
Study: NCT05838391

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Artificial Intelligence Guided Daily Radiotherapy Treatment Planning and Delivery
Description: Subjects will receive 54 Gy of radiation delivered 5 day a week for 6 weeks, 30 radiation treatments total. Intensity-Modulated photon radiation therapy will be delivered on a Varian Ethos linear accelerator. Daily image-guided radiation therapy (IGRT) is required. All treatments will have artificial-intelligence (AI) daily adaptations of the radiation plan to optimize the radiation dose to the targeted area and minimize radiation dose to the normal surrounding organs such as the bowel.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitomycin-C
Description: As part of the subjects' treatment, 10 mg/meters squared of Mitomycin C will be administered intravenously (IV-into the vein) on Day 1 and Day 29.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-Fluorouracil
Description: As part of the subjects' treatment, 1g/meters squared/day for 4 days of 5-Fluorouracil will be administered by continuous infusion on Days 1-4 (for 96 hours) and Days 29-32 (for 96 hours). 5-Fluorouracil or capecitabine will be administered per the physician's discretion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: As part of the subjects' treatment, 825 mg/meters squared per day, divided into 2 daily doses, will be taken on days of radiotherapy. Capecitabine or 5-FU will be administered per the physician's discretion.
Study: NCT05528627

Intervention type: OTHER
Group type: OTHER
Intervention: Pectoral Nerve (PECs) block
Description: Pectoral Nerve (PECS) blocks were performed on the side of surgery, using the ultrasound-guided technique 30 min before the implantable cardiac electronic device (pacemaker, implantable cardioverter defibrillator) insertion procedure
Study: NCT06467890

Intervention type: BEHAVIORAL
Intervention: Educational programme about vital pulp therapy
Description: An awareness educational material based on the recent AAPD and AAE guidelines on vital pulp therapy will be sent to the participants right after they answer the questionnaire for the first time
Study: NCT05156827

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TB006
Description: TB006 diluted in normal saline, administered through IV infusion over an hour

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Normal saline administered through IV infusion over an hour
Study: NCT06182488

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ERAS protocols
Description: ERAS protocols for emergency abdominal surgery

Intervention type: OTHER
Group type: OTHER
Intervention: Conventional protocols
Description: Conventional protocols for emergency abdominal surgery
Study: NCT04792931

Intervention type: OTHER
Group type: OTHER
Intervention: description of adult autoimmune myopathies
Description: description of adult autoimmune myopathies
Study: NCT06541873

Intervention type: OTHER
Intervention: Clinical and gait evaluation
Description: The dual-task conditions to be assessed during gait performance will include: counting backwards by 3 (executive simple task); counting backwards by 7 (executive complex task); mnemonic recall of the Rey's Auditory Verbal Learning Test (RAVLT). Performance scores will be correlated with cognitive status and clinical features. Data will be collected at the baseline (i.e., only) visit within the enrollment timeframe of 3 years from study initiation.

Intervention type: OTHER
Intervention: Clinical and gait evaluation
Description: The dual-task conditions to be assessed during gait performance will include: counting backwards by 3 (executive simple task); counting backwards by 7 (executive complex task); mnemonic recall of the Rey's Auditory Verbal Learning Test (RAVLT). Performance scores will be correlated with cognitive status and clinical features. Data will be collected at the baseline (i.e., only) visit within the enrollment timeframe of 3 years from study initiation.
Study: NCT05957172

Intervention type: DEVICE
Intervention: ZOLL Arrhythmia Management System
Description: AMS records rhythm, heart rate, subject-reported symptoms, and multiple parameters that include respiration rate, activity, and body posture (biometric data)
Study: NCT06158516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib
Description: Surufatinib 300 mg once a day (QD) will be orally administrated on a 28-day cycle
Study: NCT04808856

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adrenocorticotropic Hormone
Description: Adrenocorticotropic Hormone Injection 25u qd iv \*3d

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylprednisolone Injection
Description: Methylprednisolone Injection 40mg qd iv \*3d
Study: NCT04519645

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacosamide intravenous
Description: Study participants will receive lacosamide (LCM) as an intravenous (iv) infusion during the Treatment Period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacosamide oral
Description: Study participants may receive lacosamide (LCM) as an oral solution during the Extension Period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator
Description: Active Comparator treatment will be chosen and dosed based on StOC (per local practice and treatment guidelines).
Study: NCT04409873

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral-B Mouth Sore mouthwash
Description: Rinse and gargle 4 times daily, for 60 seconds, for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Crest Pro-Health Multi-Protection mouthwash
Description: Rinse and gargle 4 times daily, for 60 seconds, for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CloSYS Ultra Sensitive Rinse mouthwash
Description: Rinse and gargle 4 times daily, for 45 seconds, for 4 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Distilled water
Description: Rinse and gargle 4 times daily, for 60 seconds, for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Listerine Zero Mouthwash Product
Description: Rinse and gargle 4 times daily, for 30 seconds, for 4 weeks.
Study: NCT05244850

Intervention type: OTHER
Intervention: Test
Description: Measurements
Study: NCT06241612

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Individualized Elective Neck Irradiation
Description: Individualized Elective Neck Irradiation

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Individualized Elective Neck Irradiation
Description: Individualized Elective Neck Irradiation
Study: NCT05230888

Intervention type: OTHER
Intervention: Questionnaires about symptoms
Description: The CGA and VES-13 questionnaires will be conducted at baseline. Immune-related adverse events (irAEs) will be investigated at 3 and 6 months using a Patient Knows Best symptom tracker form (local Trust created).
Study: NCT04951258

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multicomponent exercise
Description: The intervention is a 60-minute session, 3 times/week, totaling 9 weeks. Multicomponent exercise included strengthening, balance training, aerobic dance, and stretching

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Video home exercise group
Description: The intervention is a 60-minute session, 3 times/week, totaling 9 weeks. Video home exercise included four limbs mobility exercise, stretching, strengthening, and aerobic exercise
Study: NCT06158516

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 300 mg once a day (QD) will be orally administrated on a 28-day cycle
Study: NCT04894929

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: multi component exercise in the clinic
Description: Patients randomly assigned to this group have a pre-fragile or fragile SPPB condition, so they will perform:~3 days of empowerment work, 4 days of flexibility work, and daily walking aerobic work and balance work.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: vestibular exercise in the clinic
Description: Patients randomly assigned to this group have a pre-fragile or fragile SPPB condition, so they will perform. sessions of about 20 minutes with 5 weekly sessions (Monday to Friday) consisting of 5 repetitions without fatigue of:~to. Head and eye movements while sitting. b. Head and body movements while sitting. c. Exercises standing. d. Combined exercises of modifications in steps, unstable surfaces and in progress.~and. Along with push up 30sec and squat 30sec

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: vestibular exercise at home telerehabilitation
Description: Patients randomly assigned to this group have a pre-fragile or fragile SPPB condition, so they will perform with the help of a video. sessions of about 20 minutes with 5 weekly sessions (Monday to Friday) consisting of 5 repetitions without fatigue of:~to. Head and eye movements while sitting. b. Head and body movements while sitting. c. Exercises standing. d. Combined exercises of modifications in steps, unstable surfaces and in progress.~and. Along with push up 30sec and squat 30sec

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: multi component exercise at home telerehabilitation
Description: Patients randomly assigned to this group have a pre-fragile or fragile SPPB condition, so they will perform with the help of a video:~3 days of empowerment work, 4 days of flexibility work, and daily walking aerobic work and balance work.
Study: NCT06101615

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: IASTM (FAT)
Description: Group-A participants would receive Facial Abrasion Technique (FAT) with an Instrument, FAT-Tool. Treatment sessions will be carried out three times per week for eight weeks after an initial warm-up session. All the sessions will be performed at the same time of day (i.e., between 4-6 pm), to avoid possible confounding circadian effects. The FAT group will receive 2 min application on the quadriceps and hamstring muscles with a FAT-tool Pro Large model, which consists of a handle and 20cm treatment surface. The muscles will be treated in a pre-stretched position, meaning a knee flexion in a supine position for the quadriceps muscle and a hip flexion and knee extension in a side-lying position for the hamstring muscles.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Foam Rolling
Description: Group-B participants would receive Foam Rolling (FR). Treatment sessions will be carried out three times per week for eight weeks after an initial warm-up session. All the sessions will be performed at the same time of day (i.e., between 4-6 pm) to avoid possible confounding circadian effects. The Foam Roller group will receive 2x1 min of FR on the quadriceps and the hamstrings on the dominant leg with the opposite leg crossed over the dominant one. During each minute the muscle will be rolled out 4-5 times, with a break of 30s in between sets. They will be instructed to utilize short, kneading like movements in one direction and a quick motion in the other direction. A grid foam roller will be utilized with a length of 33cm, diameter of 14 cm and with a hard hollow core, wrapped in ethylene vinyl acetate foam.
Study: NCT06252272

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Biopsy from patients undergoing surgery abdominal.
Description: A small portion (about 10 mm in diameter) of liver tissue was collected macroscopically free from alterations of the parenchyma obtained in the open at the site surgery for primary or secondary liver tumors, for the preparation of cultures of organotypic liver slices.
Study: NCT05495555

Intervention type: DEVICE
Intervention: INTREPID® Hybrid tip
Description: INTREPID® Hybrid tip for cataract removal

Intervention type: DEVICE
Intervention: INTREPID® Hybrid tip
Description: INTREPID® Hybrid tip for cataract removal
Study: NCT04849780

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE Oasys 1-Day
Description: TEST

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE Oasys 1-Day
Description: TEST

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Habitual Lens
Description: Subjects' own Habitual Lenses
Study: NCT04735094

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Endobronchial biopsy with the use of a balloon attached to the echo-bronchoscope
Description: A small balloon made of latex can be attached to the tip of echo-bronchoscope which is then inflated with water or saline for better apposition of the echo-endoscope and the airway wall. This may improve ultrasound image quality and aid better visualization of the lymph nodes.
Study: NCT03971110

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zoladex and Casodex
Description: The eligible subjects will receive Casodex 50 mg orally per day in combination with Zoladex 10.8 mg implant subcutaneously as neoadjuvant therapy per 12 weeks for up to 24 weeks.
Study: NCT06481761

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Double-slot brackets
Description: Miniscrews will be inserted in the buccal alveolar bone between first and second molars bilaterally and ligated to second premolar.~Canine Retraction using Nickel titanium closed-coil springs delivering a force of 150 gram, extending the spring between the canine and first molar hooks.~retraction on double 0.016'' Stainless steel round wires in both slots of the double slot brackets.~Re-activation of the coil spring will be done in the follow up visits to maintain a constant force through the study.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Single-slot brackets
Description: Miniscrews will be inserted in the buccal alveolar bone between first and second molars bilaterally and ligated to second premolar.~Canine Retraction using Nickel titanium closed-coil springs delivering a force of 150 gram, extending the spring between the canine and first molar hooks.~retraction on single 0.017x0.022'' Stainless steel wire. Re-activation of the coil spring will be done in the follow up visits to maintain a constant force through the study.
Study: NCT03495986

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Functional Electrical Stimulation Leg Cycle Ergometry
Description: Exercise training will consist of three to five, 40-67 minute sessions (200 minutes at target intensity) each week for a total of 16 weeks at 70% maximal heart rate; 10-minute warm-up and cool-down sessions will accompany each exercise session.
Study: NCT06459245

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance training
Description: Bend the dumbbell, holding one dumbbell in each hand, on the side of the body, bend the arm to lift the dumbbell, front wall and upper arm as close as possible, pause for a moment, and then slowly lower the dumbbell until both arms are completely straight The second section of the dumbbell side flat, straight back, feet standing, arms perpendicular to the side of the body, hands grasp the dumbbell, to the side above the shoulder level, elbow slightly bent, and then put back in place The third section of the dumbbell rowing, feet stand straight, hold the dumbbell, the arm as far back as possible, can feel the upper arm and the waist back is stretched, and then straight back into the preparatory position Section 4: Lift the dumbbell flat in front of you, with your feet open, hold the dumbbell with both hands, extend your arms naturally in front of you, lift the dumbbell to the elbow above shoulder height, stay for 1-2 seconds.
Study: NCT04460235

Intervention type: DRUG
Group type: OTHER
Intervention: Prevenar13 Pneumo-23
Description: Vaccination according national guidelines
Study: NCT05507866

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CSNEI
Description: CSNEI is a policy intervention designed to address childhood obesity by modifying lunch and breakfast meal/menu items, changing the school cafeteria environments, and making changes to purchasing and procurement practices.
Study: NCT05987111

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pilates
Description: Pilates exercises were applied twice a week for 4 weeks in both groups. The sessions were supervised by an Australian Physiotherapy and Pilates Institute (APPI) certified physiotherapist as 5 minutes of warm-up, 45 minutes of exercise and 5 minutes of cool-down periods.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pilates
Description: Pilates exercises were applied twice a week for 4 weeks in both groups. The sessions were supervised by an Australian Physiotherapy and Pilates Institute (APPI) certified physiotherapist as 5 minutes of warm-up, 45 minutes of exercise and 5 minutes of cool-down periods.