TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06739525

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Blue Light-Blocking Glasses (Intervention Group)
Description: Participants in this arm wore blue light-blocking glasses designed to filter out a portion of short-wavelength blue light. These lenses were intended to reduce eye strain and protect against blue light exposure, especially during prolonged screen time. Participants used blue light-blocking glasses consistently throughout the study period to assess their effect on contrast sensitivity and visual fatigue.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Standard Lenses (Control Group)
Description: Participants in this arm wore standard lenses without any blue light-blocking properties. These lenses allow the full spectrum of visible light to pass through and serve as a baseline control to measure against the blue light-blocking glasses. Participants used these lenses under the same conditions to assess contrast sensitivity and visual fatigue without blue light filtration.
Study: NCT06736886

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Light application
Description: Light application

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Light application
Description: Light application
Study: NCT06738355

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PREVENT
Description: The proposed study will assess the effectiveness of clinic-based outreach to increase vaccination rates for HPV at community clinics in rural counties. The study includes the following: (1) Boot camp translation to tailor messaging based on patient and provider input; (2) PREVENT randomized controlled trial (RCT) that will assign adult parent/caregiver participants to a timeline for receiving the vaccination messaging intervention; and (3) qualitative interviews with parents/caregivers, providers, and other healthcare team members and development of best practices, implementation guides and dissemination of findings for other clinics to implement the program on a broader scale. The BCT process will define the format (mode and frequency) and content of messages to promote vaccine series completion. Auto and Auto-Plus intervention arms may use some of the same components (automated calls, live calls, text messages, emails, and mailings).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PREVENT
Description: The proposed study will assess the effectiveness of clinic-based outreach to increase vaccination rates for HPV at community clinics in rural counties. The study includes the following: (1) Boot camp translation to tailor messaging based on patient and provider input; (2) PREVENT randomized controlled trial (RCT) that will assign adult parent/caregiver participants to a timeline for receiving the vaccination messaging intervention; and (3) qualitative interviews with parents/caregivers, providers, and other healthcare team members and development of best practices, implementation guides and dissemination of findings for other clinics to implement the program on a broader scale. The BCT process will define the format (mode and frequency) and content of messages to promote vaccine series completion. Auto and Auto-Plus intervention arms may use some of the same components (automated calls, live calls, text messages, emails, and mailings).
Study: NCT06736938

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol 1%
Description: Propofol 1% is infused intravenously, initially at a bolus dose of 0.5 mg/kg followed by a maintenance dose in a continuous infusion of 0.5-1.0 mg/kg/hour.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol 1%
Description: Propofol 1% is infused intravenously, initially at a bolus dose of 0.5 mg/kg followed by a maintenance dose in a continuous infusion of 0.5-1.0 mg/kg/hour.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam
Description: Midazolam is administered intravenously at an initial dose of 2 mg, as a bolus, followed by aliquots of 0.5 mg or 1 mg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam
Description: Midazolam is administered intravenously at an initial dose of 2 mg, as a bolus, followed by aliquots of 0.5 mg or 1 mg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pethidine
Description: Pethidine (100 mg/2 ml) is administered intravenously at a dosage of 0.5 mg/kg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pethidine
Description: Pethidine (100 mg/2 ml) is administered intravenously at a dosage of 0.5 mg/kg.
Study: NCT05381636

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Systemic intravenous chemotherapy
Description: Albumin paclitaxel 125 mg / m2, D1, D8 + cisplatin 75 mg / m2, D1, every 3 weeks for 1 cycle
Study: NCT06104774

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi Exercise
Description: The experimental group will receive Tai Chi exercise and routine treatment after the operation, and after discharge from the hospital, they will perform Tai Chi exercise three times a week, 50 minutes each time, for a total of eight weeks after discharge.
Study: NCT06781840

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Playing Playfully to Overcome Adversity
Description: The intervention will consist of two parts: (a) five 45-minute-long parent group online sessions; and (b) one 30-minute long online guided play session with OTS/OT.The training will consist of asynchronous module and PowerPoint presentations followed by role play and discussions.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Playing Playfully to Overcome Adversity
Description: The intervention will consist of two parts: (a) five 45-minute-long parent group online sessions; and (b) one 30-minute long online guided play session with OTS/OT.The training will consist of asynchronous module and PowerPoint presentations followed by role play and discussions.
Study: NCT05428826

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Phase 4 Prednisone Dose : 1mg/kg/day at inclusion Route of administration : oral Duration of treatment: 9 to 21 months.
Study: NCT06780189

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking
Description: This study is designed to evaluate the relationship between passive smoking and the vital parameters of children undergoing deep sedation. Additionally, the study aims to comprehensively assess and document the entire treatment process from start to finish by using the RASS, MASS, and PAED scales for postoperative evaluation.
Study: NCT06661265

Intervention type: PROCEDURE
Intervention: adjuvant tomotherapy +- chemotherapy after the reconstructive surgery with flaps
Description: adjuvant treatment in locally-advanced head and neck cancers submitted to upfront surgery with flap reconstruction, evaluation of toxicity and flap status performed at San Raffaele Hospital between December 2017-December 2022.
Study: NCT06671145

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: catheter ablation
Description: Catheter ablation after differentiating Atrioventricular Nodal Reentry Tachycardia from Orthodromic Atrioventricular Reentry Tachycardia during electrophysiological study.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: catheter ablation
Description: Catheter ablation after differentiating Atrioventricular Nodal Reentry Tachycardia from Orthodromic Atrioventricular Reentry Tachycardia during electrophysiological study.
Study: NCT06673160

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pumping every 2 hours
Description: The intervention will be pumping every 2 hours.
Study: NCT05663255

Intervention type: DRUG
Intervention: Discontinuation of respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)
Description: Discontinuation or reduction of at least one respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)
Study: NCT06673160

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: breast pumping every 3 hours
Description: The intervention will be pumping every 3 hours
Study: NCT06673121

Intervention type: DRUG
Intervention: Traditional Chinese Medicine
Description: Received treatment with traditional Chinese medicine
Study: NCT06672588

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Seizure Therapy (MST)
Description: MST treatment will be administered using the MagPro MST with a Cool TwinCoil over the frontal cortex in the midline position using 100 Hz stimulation at 100% machine output. Seizure threshold will follow prior protocols used for frontal MST. Patients will receive care and be managed by anaesthesia as per standard ECT practice.
Study: NCT05882526

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BURSTONE T-LOOP
Description: Split mouth study one side using elastomeric power chain and other side using T loops

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BURSTONE T-LOOP
Description: Split mouth study one side using elastomeric power chain and other side using T loops
Study: NCT06672588

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electroconvulsive Therapy (ECT)
Description: In the ECT arm treatment, the MECTA spectrum 5000Q or MECTA sigma machine will be used. The ECT determination of seizure threshold and the adjustment of energy at subsequent sessions will be based on a standard published protocol. All participants will receive RUL-UB ECT at six times the seizure threshold. Patients will receive care and be managed by anaesthesia as per standard ECT practice.
Study: NCT06672211

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: video-supported training
Description: Patients with stomas were provided with video-supported training in addition to standard stoma care training.
Study: NCT06672029

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: combining pattern-specific manual therapy, Schroth Best Practice exercise, and Gensingen brace application
Description: * The pattern-specific manual therapy: It was developed by our author. This therapy was done immediately before each SBP (Schroth Best Practice) exercise session, targeting both the spine and extra-spinal regions.~* The Schroth Best Practice exercises: It contains following 6 components: The physio-logic® program for sagittal profile correction, education on activities of daily living (ADLs), the 3D made easy program, the new Power Schroth program, the rehabilitation of walk, and neuromobilization.~* The Gensingen brace application: it was made according to the patients' Lehnert Schroth Classifications. the investigators recommended the patients to wear the brace for 21-23 hours per day during the first year. As the bone maturation reached Risser 4 to 4.5, the daily brace wearing time was gradually reduced.
Study: NCT06630832

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Simulated work in the heat with no cooling during rest breaks
Description: Young and older adults will not undergo cooling during rest breaks applied during the implementation of work-rest allocations over the duration of a 180-min work period following a continuous work bout to 38.0°C (equivalent to a 1°C increase in body core temperature above resting levels).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simulated work in the heat with partial cooling during rest breaks
Description: Young and older adults will not undergo partial cooling during rest breaks applied during the implementation of work-rest allocations over the duration of a 180-min work period following a continuous work bout to 38.0°C (equivalent to a 1°C increase in body core temperature above resting levels).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simulated work in the heat with full cooling during rest breaks
Description: Young and older adults will not undergo full cooling during rest breaks applied during the implementation of work-rest allocations over the duration of a 180-min work period following a continuous work bout to 38.0°C (equivalent to a 1°C increase in body core temperature above resting levels).
Study: NCT06003816

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) CATI
Description: The CHoBI7 program is during group sessions by a health promoter to those residing in a ring around a cholera patient reinforced through weekly voice and text messages from the CHoBI7 mHealth program over 12 months on the recommended water, sanitation, and hygiene behaviors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard message
Description: Standard message given in the Democratic Republic of the Congo to diarrhea patients at health facility discharge on use of oral rehydration solution
Study: NCT06123429

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Stress reduction
Description: The MBSR course will consist of weekly sessions lasting two and a half hours, involving lecture, meditation, and self-reflection.~Mindfulness-Based Stress Reduction (MBSR) is a structured program designed to help individuals manage stress, increase self-awareness, and promote overall well-being. Developed by Dr. Jon Kabat-Zinn in the late 1970s, MBSR combines elements of mindfulness meditation and cognitive-behavioral techniques. MBSR is a comprehensive program that equips individuals with practical skills to better manage stress and enhance their mental and emotional well-being. Its emphasis on mindfulness, self-awareness, and the integration of these practices into daily life makes it a valuable resource for those seeking to reduce stress and improve their overall quality of life.
Study: NCT04634539

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine will be administered at 600, 800, or 1000 mg/m2 intravenous (IV) infusion over 30 minutes on days 1, 8, and 15 (every 28-day cycles) during the treatment period. Gemcitabine will be administered immediately after the infusion of nab-paclitaxel. Pre-medication with may be administered per institutional standard practice at the investigator's discretion with gemcitabine.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab-paclitaxel
Description: Nab-paclitaxel will be administered at 75, 100, or 125 mg/m2 intravenous (IV) infusion over 30 minutes on days 1, 8, and 15 (every 28-day cycles) during the treatment period. Nab-paclitaxel will be given first, before infusion of gemcitabine. Pre-medication for nab-paclitaxel may be administered per institutional standard practice at investigator's discretion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-glutamine
Description: The dose levels of L-glutamine in this study will be 0.1, 0.2, and 0.3 g/kg oral twice daily (rounded to nearest 5 g with an upper limit of 15 g twice daily (30 g/day) for any dose level) taken at the same time each day during the treatment period. L-glutamine will be administered for 1 week (+/-1 day) prior to addition of gemcitabine/nab-paclitaxel. Each dose of L-glutamine should be mixed immediately before ingestion with 8 oz. (240 mL) of a cold or room temperature beverage, such as water, milk or apple juice, or 4 oz. (120 mL) to 6 oz. (177 mL) of food such as applesauce or yogurt. L-glutamine is formulated in 5 gram packets as a white crystalline powder in paper-foil-plastic laminate. Complete dissolution is not required prior to administration.
Study: NCT04955990

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PAH Therapies
Description: No Drug will be administered as part of this study. Real world data will be collected in participants who newly initiate PAH therapies in routine clinical setting or have already been receiving macitentan 10 mg for at least 3 months prior to the index date.
Study: NCT05664646

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DS8R
Description: transcutaneous stimulation of the spinal cord.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Arm Ergometry
Description: Study 1 will use the arm ergometry as a form of exercise.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Arm Ergometry
Description: Study 1 will use the arm ergometry as a form of exercise.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cool Environment
Description: Study 2 will be completed in a cool environment setting.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Cool Environment
Description: Study 2 will be completed in a cool environment setting.
Study: NCT04951206

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fractionated CO2-laser
Description: All women will be undergoing FxCO2-laser therapy as this treatment is a criterion for enrollment.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Fractionated CO2-laser
Description: All women will be undergoing FxCO2-laser therapy as this treatment is a criterion for enrollment.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clobetasol Propionate 0.05% Ointment
Description: Clobetasol propionate 0.05% ointment obtained from a commercial manufacturer
Study: NCT05026385

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Targeted nutrition advice, progressive resistance training exercise, and self-management support
Study: NCT06332963

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Floatation-REST
Description: Participants lay supine in one of two circular fiberglass pools that were custom-designed for research purposes. The floatation pools are 8 feet in diameter and contain 11 inches of reverse osmosis water saturated with \~1,800 pounds of Epsom salt (magnesium sulfate). This creates a dense saltwater solution with a specific gravity of \~1.26, allowing participants to effortlessly float on their back while the water hovers just above the ears. The temperature of the water and air is calibrated to approximate skin temperature (\~95.0 °F), helping to minimize the need for thermoregulation while reducing the boundary between air, body, and water. Clothing is usually not worn while floating since anything touching the body can generate somatosensory stimulation, detracting from the float experience. However, participants have the option to choose if they would prefer to float with a bathing suit or nude. During floatation-REST, visual, auditory, olfactory stimuli are minimized.
Study: NCT06780189

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking
Description: This study is designed to evaluate the relationship between passive smoking and the vital parameters of children undergoing deep sedation. Additionally, the study aims to comprehensively assess and document the entire treatment process from start to finish by using the RASS, MASS, and PAED scales for postoperative evaluation.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking
Description: This study is designed to evaluate the relationship between passive smoking and the vital parameters of children undergoing deep sedation. Additionally, the study aims to comprehensively assess and document the entire treatment process from start to finish by using the RASS, MASS, and PAED scales for postoperative evaluation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Not Exposed to Passive Smoking
Description: This study is designed to measure the differences in vital parameters of children undergoing deep sedation who are not exposed to passive cigarette smoke at home. Furthermore, the study aims to comprehensively evaluate and document the entire treatment process from start to finish using the RASS, MASS, and PAED scales for postoperative assessment.
Study: NCT06332963

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IFT
Description: Two ACT principles, contact with the present moment and cognitive defusion were utilized in the development of the intervention. In the IFT condition, awareness and acceptance of bodily signals, thoughts, and emotions and being present with one's self (i.e., mindfulness focus is inward) are emphasized. All participants will engage in an introduction session. Followed by three IFT sessions. The experimental sessions are formatted the same for both conditions. Each begins with a clinician reviewing previous constructs and introducing a new skill. Then participants engage in their assigned condition intervention, followed by a debrief with a clinician. Practices in both conditions are matched as closely as possible for content. The mindful focus of IFT is internal toward thoughts, emotions, and body sensations. In the experimental sessions, participants will engage in a floatation-REST session while practicing acceptance and mindfulness-based skills presented to them.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: EFT
Description: Two acceptance and commitment therapy modules contact with the present moment and cognitive defusion were utilized in the development of the intervention. In the EFT condition, awareness and acceptance of thoughts and emotions and mindfulness of current experience are emphasized. The mindful focus of EFT is external, toward attending to experience as well as thoughts and emotions. During experimental sessions, participants will engage in a self-guided and computer-based practice of acceptance and mindfulness-based skills. These videos were created to ensure content was congruent with the material presented in the introduction sessions and represent skills that build from session to session.
Study: NCT06173752

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exposure therapy
Description: Participants will complete exposure therapy for up to 12 weeks, and coached exposure session will be approximately 50 minutes.
Study: NCT06248008

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASC40
Description: ASC40 tablets orally once daily
Study: NCT05955027

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZX-7101A
Description: a drug to treat influenza, oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZX-7101A
Description: a drug to treat influenza, oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: placebo control, oral

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo control, oral