TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05550753

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Better Together Physician Coaching Program
Description: thought-based coaching. This type of coaching focuses on thoughts and beliefs. It combines a cognitive behavioral therapy (CBT) model with mindfulness-based awareness and integrates theories of acceptance and commitment therapy (ACT), nonattachment, and radical questioning from Socratic and Greek philosophies.4 BT delivers a robust coaching experience via a 4-month web-based, group-coaching model. This novel program allows residents to participate as actively as they are inclined and able, offering flexibility via multiple modalities of coaching: twice weekly group coaching calls, unlimited anonymous written coaching, and weekly self-study modules that are housed on a secure members-only website.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: No intervention - placebo control
Description: No intervention - placebo control
Study: NCT05236647

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: Intravenous morphine infusion compared to subcutaneous morphine infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Intravenous morphine infusion compared to subcutaneous morphine infusion
Study: NCT06070675

Intervention type: DEVICE
Group type: OTHER
Intervention: Minze Diary Pod
Description: The automated bladder diary utilized in this study consists of the Minze Diary Pod and Minze Flow app. The Diary Pod is a capacitance-based measuring device, that automatically registers voided volumes and time of void. The Diary Pod connects via Bluetooth to the Minze Flow app to request additional information from the patient, such as urge, drinks and leakages.

Intervention type: OTHER
Group type: OTHER
Intervention: Paper bladder diary
Description: The paper bladder diary utilized in this study is a paper timetable that has the patient enter (in the columns of the timetable) drinks in ml, urinations in ml (using a measuring cup) and leakage episodes for the nearest hours (rows of the timetable).
Study: NCT06197477

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OurAir SQ 1750 - Mobile Air Purification System for indoor
Description: Filtration device will be placed in classrooms. Computational Fluid Dynamics simulations will be used to find optimal position and operation mode for air purification systems in classrooms.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham intervention
Description: Filtration will be turned off in the control part of the study and then will be turned on during the intervention.
Study: NCT05943431

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: paired taVNS
Description: The stimulator will be placed on the left ear of the patient. While the patient performs the action training, the EMG signal feature evoked by the action will trigger an electrical stimulation of the transcutaneous auricular vagus nerve. The amplitude of the electrical stimulation will be adjusted under the patient's pain threshold. The intervention will be performed daily for 14 days.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Unpaired taVNS
Description: The stimulator will be placed on the patient's left ear. Patients will receive taVNS with pulses every 5-7 seconds. Following the stimulation, motor training will be performed. The motor training will be identical to that of the paired group. The amplitude of the electrical stimulation will be adjusted under the patient's pain threshold. The intervention will be performed daily for 14 days.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham taVNS
Description: The stimulator will be placed on the patient's left ear. The amplitude of the electrical stimulation will be adjusted at 0 mA. The intervention will be performed daily for 14 days.
Study: NCT04350177

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IkT-148009
Description: Oral administration gelatin capsule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IkT-148009
Description: Oral administration gelatin capsule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IkT-148009
Description: Oral administration gelatin capsule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Oral administration gelatin capsule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Oral administration gelatin capsule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Oral administration gelatin capsule
Study: NCT06041282

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: manipulation under anesthesia
Description: After the anesthesia took effect, the patient was placed in the supine position, and the experienced surgeon stood at the head of the bed to release the affected limb by four angles of forward flexion, abduction, external rotation and internal rotation. After the operation is completed, 1ml de Bosson (MSD) +2.5ml sodium hyaluronate (Biochemical Industries Co., LTD.) is injected once.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: supervised home rehabilitation
Description: The doctor instructs the patient in exercise training at the outpatient clinic. At each clinic visit, the doctor will guide the different stages of the movement. At the first visit, the doctor guides the patient through the first phase of the rehabilitation program to improve the patient's basic mobility. At the first month of follow-up, the second phase of rehabilitation program was guided, and the recovery of mobility was accompanied by muscle training, including wall climbing and muscle resistance exercises. 1ml Debossone (MSD) +2.5ml sodium hyaluronate (Biochemical Industries Co., LTD.) was injected once at the clinic. All the training required patients to do their best at home to complete 3 sets of 5 each. At the end of each day, the patient will upload a video to the platform, and the doctor will evaluate whether the patient's recovery is in place.
Study: NCT05951920

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lymph node aspiration / Blood sampling
Description: Lymph node aspiration / Blood sampling
Study: NCT05688163

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: programme based on everyday cognition
Description: Will carry out a programme based on everyday cognition, As material for use as for the traditional cognitive stimulation sessions, a training booklet on everyday cognition has been created which includes all the sessions mentioned above. Each day one of these tasks will be worked on.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional cognitive stimulation
Description: Individual cognitive skills such as attention, memory, executive functions, orientation, praxis, calculation, visual perception and reasoning will be trained. The materials and media used will be a cognitive stimulation notebook created for the study which includes cards in printed paper format to be completed by the participants.
Study: NCT04727983

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electrotherapy
Description: The first group will be given Neuromuscular Electrical Stimulation (NMES) and lifestyle suggestions (LSS) (NMES group)

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Electrotherapy
Description: The second group will be given sham NMES in addition to LSS (SHAM ES group)
Study: NCT05333874

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neoadjuvant chemotherapy administered before surgical extraction of a tumor
Description: SignateraTM is a custom-built circulating tumor DNA (ctDNA) test for treatment monitoring and molecular residual disease (MRD) assessment in patients previously diagnosed with cancer. The Signatera methodology is personalized and tumor-informed, providing each individual with a customized blood test tailored to fit the unique signature of clonal mutations found in that individual's tumor tissue. This maximizes accuracy for detecting the presence or absence of disease in a blood sample, even at levels down to a single tumor molecule in a tube of blood. Signatera is intended to detect and quantify how much cancer is left in the body, to improve prognosis and help optimize treatment decisions, based on the tissue-informed testing of mutations.

Intervention type: OTHER
Group type: OTHER
Intervention: Observational
Description: In participants, undetectable ctDNA at fourteen days will be in the observation arm (observation defined as TNBC: No adjuvant chemotherapy. Participants may complete checkpoint inhibitor from neoadjuvant setting; HER2 positive BC: Completed one year of anti-HER2 therapy from the neoadjuvant setting). No investigational drugs will be used. Samples of ctDNA will be collected at time points described in the study arm.
Study: NCT04923308

Intervention type: OTHER
Intervention: Triage results disclosed
Description: Following the chiropractor triage assessment, the working diagnosis and risk stratification or referral need will be communicated to the specialist using a standardized clinical note, prior to the patient's consultation and without further discussion.

Intervention type: OTHER
Intervention: Triage results undisclosed
Description: Following the chiropractor triage assessment, the working diagnosis and risk stratification or referral need will not be communicated to the specialist.
Study: NCT04415853

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lerotinib
Description: Specification: 50 mg/capsule and 150 mg/capsule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Irinotecan/Tegafur
Description: Irinotecan:Specification: 2mL: 40mg;5mL:0.1g Tegafur:20mg/capsule
Study: NCT04980079

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary ureterscopy URS
Description: Ureteral dilatation will be done when the stone size exceeds 10 mm to facilitate the extraction of the fragments. Ureteroscopic lithotripsy will be done using a 6.5:7.5 Fr semi-rigid ureteroscope and holmium laser. The ureteric stent will last for one week after lithotripsy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: deferred ureteroscopy URS
Description: insertion of a double -J stent or percutaneous nephrostomy (PCN) at first , then a deferred ureteroscopy URS will be done .
Study: NCT05339347

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Photoneuromodulation
Description: Treatments were administered daily for a period of 2 weeks (10 sessions) with a Light-Aid (Bright Photomedicine, SP, Brazil), continuous wave, 300 LED wavelength 850 nm) or with a placebo probe of the same appearance and display. The irradiation parameters created will be based on the disease, pain intensity and skin phototype. Each session has from 10 to 15 min, depending on skin phototype

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Photoneuromodulation
Description: Treatments were administered daily for a period of 2 weeks (10 sessions) with a Light-Aid (Bright Photomedicine, SP, Brazil), continuous wave, 300 LED wavelength 850 nm) or with a placebo probe of the same appearance and display. The irradiation parameters created will be based on the disease, pain intensity and skin phototype. Each session has from 10 to 15 min, depending on skin phototype
Study: NCT04911478

Intervention type: GENETIC
Intervention: ADI-001
Description: No study drug is administered in this study. Patients who have received Adicet allogeneic γδ CAR T cell therapy will be evaluated in this trial for long-term safety and efficacy
Study: NCT06408779

Intervention type: PROCEDURE
Intervention: mitral valve repair
Description: coronary artery bypass grafting concomitant mitral valve repair

Intervention type: PROCEDURE
Intervention: mitral valve repair
Description: coronary artery bypass grafting concomitant mitral valve repair
Study: NCT04358315

Intervention type: BEHAVIORAL
Intervention: Behavioral Intervention
Description: Smell or puff e-liquids

Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05907252

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supervised Group-based Intervention
Description: The intervention will be an 18-week walking program, with 3 times per week on alternative days. A 2-week basic walking practice with 3 sessions per week, 30-45 minutes per session, and being led by a certified walking trainer. The walking practice will take reference from the exercise procedure recommended by the Healthy Exercise for All Campaign (LCSD, Department of Health, and Physical Fitness Association Hong Kong, China, 2013). Upon completion of the 2-week basic walking practice, participants will enter week-3 to week-18 main walking program, in which the duration of each training session will increase to 45-70 minutes, depending on the levels of training. In the walking programs, the progressive training principle (ACSM, 2009) will be adopted, using 4 levels as prescribed, in which weeks 3 to 6 are Level-1; weeks 7 to 10 are Level-2, weeks 11 to 14 are Level-3, week 15-18 are Level-4.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Non-supervised Group-based Intervention
Description: The intervention will be an 18-week walking program, with 3 times per week on alternative days. A 2-week basic walking practice with 3 sessions per week, 30-45 minutes per session, and without being led by a certified walking trainer. The walking practice will take reference from the exercise procedure recommended by the Healthy Exercise for All Campaign (LCSD, Department of Health, and Physical Fitness Association Hong Kong, China, 2013). Upon completion of the 2-week basic walking practice, participants will enter week-3 to week-18 main walking program, in which the duration of each training session will increase to 45-70 minutes, depending on the levels of training. In the walking programs, the progressive training principle (ACSM, 2009) will be adopted, using 4 levels as prescribed, in which weeks 3 to 6 are Level-1; weeks 7 to 10 are Level-2, weeks 11 to 14 are Level-3, week 15-18 are Level-4.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Non-supervised Individual-based Intervention
Description: The intervention will be an 18-week walking program, with 3 times per week on alternative days. A 2-week basic walking practice with 3 sessions per week, 30-45 minutes per session, and without being led by a certified walking trainer. The walking practice will take reference from the exercise procedure recommended by the Healthy Exercise for All Campaign (LCSD, Department of Health, and Physical Fitness Association Hong Kong, China, 2013). Upon completion of the 2-week basic walking practice, participants will enter week-3 to week-18 main walking program, in which the duration of each training session will increase to 45-70 minutes, depending on the levels of training. In the walking programs, the progressive training principle (ACSM, 2009) will be adopted, using 4 levels as prescribed, in which weeks 3 to 6 are Level-1; weeks 7 to 10 are Level-2, weeks 11 to 14 are Level-3, week 15-18 are Level-4.
Study: NCT05951023

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eszopiclone 2 mg
Description: Eszopiclone tablet (encapsulated)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sugar capsule manufactured to match encapsulated Eszopiclone
Study: NCT05730491

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Learning and Cognitive Behavioral Therapy (SLCBT)
Description: Participants assigned to this group will complete an online program with 3 core skills, which will include strategies to promote wellness behaviors, use adaptive cognitive coping strategies, model wellness behaviors for their children, and determine when it is appropriate to take further action re: potential illness in their child. The website is interactive and self-guided. All participants will have access to the same resources and content, although based on responses to quizzes and skills practice questions, the automated feedback may differ slightly. The website includes treatment modules that share content via text, images, videos and recordings, a skills library that includes audio recordings of relaxation exercises, infographics to support skills practice, and behavioral assignments to record skills practice and receive automated feedback. Participants will review their knowledge at the end of each treatment module with brief quizzes.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Attention Education Control
Description: Participants assigned to the control group will receive access to a web program and complete 3 modules focused on child health and safety behaviors, such as sports and water safety. These participants will review written/visual content on the above topics, take quizzes to test knowledge gained, and will be provided with brief assignments to increase child safety behaviors. All participants assigned to the control group will have access to the same educational content.
Study: NCT06730984

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Endoscopy-Assisted Tracheal Intubation
Description: Tracheal Intubation Under Endoscopic Guidance

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Tracheal Intubation
Description: Tracheal Intubation Under Video Laryngoscopy
Study: NCT05790005

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: therapeutic play
Description: 2 days after the operation, 1 hour before the dressing, a warm-up game will be played with the child in the playroom of the pediatric surgery service, aiming to put the organs prepared by the researcher in their correct places on the picture for the first 10 minutes. Then, the teddy bear, which is given the appearance of an operation area by sewing a zipper on his stomach, will be given to the child and he will be asked to make the first dressing of the teddy bear. therapeutic game, in which the dramatization method is used, will last 20 minutes. During the 30-minute play practice, the child's questions will be answered.
Study: NCT04650698

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid (TXA) injection
Description: IV, Total Dosage: 2 grams (1 gram before surgical incision + 1 gram, 3 hours after first dose)
Study: NCT04672876

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Telotristat Ethyl Oral Tablet
Description: XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy. The drug is currently FDA-approved for this use but this study has received special approval from the FDA (under an Investigational Drug Application) to study telotristat ethyl in individuals with carcinoid tumors who plan to undergo surgery.
Study: NCT05700331

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fecal Microbiota Transplantation
Description: FMT performed at week 0, week-2 and week-4: FMT solution will be prepared using stool from a single donor or mixing of stool from multiple donors. Feces will be diluted with sterile saline (0.9%). This solution will be blended and strained with filter. The resulting supernatant will then be used directly as fresh FMT solution or stored as frozen FMT solution for future FMT.~Procedures for Infusion: 100-200 ml of FMT solution or sterile saline will be infused over 2-3 minutes into the distal duodenum or jejunum via oesophago-gastro-duodenoscopy (OGD). After infusion, subjects will be monitored for 1 hour before discharged.~2 study biopsies in total (from duodenum) will be obtained during FMT infusion via OGD.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sigmoidoscopy
Description: Optional sigmoidoscopy will be done at week 0 and week 4, during which 2 study biopsies in total (obtained via sigmoidoscopy) will be obtained from the rectum.
Study: NCT05430477

Intervention type: DEVICE
Intervention: Electrical impedance imaging using Non-Significant Risk device (EII probe)
Description: novel small field-of-view Non-Significant Risk device (EII probe)

Intervention type: DEVICE
Intervention: Electrical impedance imaging using Non-Significant Risk device (EII probe)
Description: novel small field-of-view Non-Significant Risk device (EII probe)
Study: NCT04278586

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Live-Online M-ROCC
Description: 1. LDM (Low-Dose Mindfulness): A 4-wk intro mindfulness program for OUD, 50-60 min/week including explicit training in use of mobile mindfulness apps, with rolling admission and ascending practice dose ladder.~2. MTPC (Mindfulness Training for Primary Care): An eight-week intensive mindfulness group with ascending practice dose ladder and skill integration over 16 weeks with 60 minutes/wk.~3. MCS (Mindfulness Maintenance Check-in Support): Ongoing weekly mindfulness group with check-in and reminders, leveraging mobile mindfulness apps and motivational counseling for graduates of LDM for 50-60 mins/wk.~After completion of the LDM group, participation in various levels is fluid based on patient motivation, choice, and readiness.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Live-Online Control
Description: A time- and attention-matched live online control group. The manualized control intervention developed for the basic group-based opioid treatment group in primary care uses 16 core modules and 8 elective modules that are common to eclectic approach in treatment as usual addiction recovery groups (including engagement and group development activities with a mix of basic CBT skills, twelve-step facilitation, community reinforcement, and motivational interviewing). As an active group control, this method will help to isolate mindfulness as the putative mechanism of action by controlling for the therapeutic aspects of group without any reference to mindfulness.
Study: NCT05895708

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Specific strengthening and stretching exercise
Description: The program consisted of two strengthening (deep cervical flexors and shoulder retractors) and two stretching (cervical extensors and pectoral muscles) exercises based on Harman and Mostafa et al's approach. This exercise program will be repeated 4 times per week for 10 weeks, and each session lasted for 30 minutes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: General Exercise
Description: The program will consist of regular general postural exercises such as postural awareness exercises as well as general strengthening exercises such as range of motion exercises for the upper quadrant. The program will also be repeated 4 times per week for 10 weeks, with each session lasting 30 minutes
Study: NCT06171555

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CTM
Description: decellularized particulate human placental connective-tissue matrix products, intended solely for homologous use to supplement or replace damaged or inadequate connective-tissue. These are structural tissue allografts processed according to the criteria contained in 21CFR 1271.10(a) for regulation solely under section 361 of the Public Health Service Act.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Celestone
Description: standard of care