TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06257810

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: VIDAS® Dengue Antigen NS1, VIDAS® Anti-Dengue IgM, VIDAS® Anti-Dengue IgG, VIDAS® Anti-Chikungunya IgM and VIDAS® Anti-Chikungunya IgG
Description: For patients managed in an intervention site, a diagnostic test for dengue and chikungunya using VIDAS® as well as a screening test for malaria will be carried out. An awareness campaign on the use of VIDAS® diagnostic tests will be implemented as well.~The diagnosis will be based on the patient's clinical symptoms, the biological results of the VIDAS® tests for dengue and chikungunya, as well as the results of the tests for malaria.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard of care practices
Description: For patients managed in a control site, the standard of care practices will be applied in the case of a febrile condition of undetermined etiology. This includes clinical diagnosis and, where appropriate, the use of routinely available diagnostic tests. At the end of the study, the collected samples will be tested using VIDAS® differential diagnosis tests to estimate the number of cases of dengue and chikungunya that have not been correctly diagnosed.
Study: NCT06242249

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-BCMA CAR-NK
Description: Ten eligible patients with relapsed refractory multiple myeloma will be enrolled based on inclusion criteria and informed consent. After conditioning with Fludarabine and Cyclophosphamide, patients will receive a single infusion of BCMA CAR NK cells with close monitoring using one of the following dose levels:~* Dose Level 1: 1×10\^7/Kg~* Dose Level 2: 5×10\^7/Kg~* Dose Level 3: 1×10\^8/Kg Safety Assessment: Adverse events will be recorded and graded. Laboratory parameters and cytokine release syndrome (CRS) markers will be closely monitored. Efficacy Evaluation: Response assessments will follow IMWG guidelines, including complete response (CR), partial response (PR), stable disease (SD), and progressive disease.
Study: NCT06399185

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: 20 ml of normal saline is infused intravenously at 80 ml/h after anesthesia induction but before surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine 0.5 μg/kg, diluted with normal salinet o 20 ml, is infused intravenously at 60 ml/h after anesthesia induction but before surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: Esketamine 0.25 mg/kg, diluted with normal saline to 20 ml, is infused intravenously at 80 ml/h after anesthesia induction but before surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combined dexmedetomidine-esketamine
Description: Dexmedetomidine 0.5 μg/kg and esketamine 0.25 mg/kg, diluted with normal saline to 20 ml, is infused intravenously at 80 ml/h after anesthesia induction but before surgery.
Study: NCT04895696

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afimetoran
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afimetoran
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afimetoran
Description: Specified dose on specified days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Specified dose on specified days
Study: NCT05413135

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-APOC3
Description: ARO-APOC3 Injection
Study: NCT06575569

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: high-intensity interval training
Description: Patients had no adverse events after 2 weeks of adaptive exercise training and voluntarily continued participants, intensive interval training under the care of specialists for 12 weeks, 30-40 minutes per week, including starting 5-minute warm-up and last 5-minute cooling-off period, during exercise including 4 intervals, 85-95% of maximum heart rate (HR) reserve for 4 minutes, followed by 50-70% of maximum HR reserve for 3 minutes, so cycling 4 times. Specific exercise logs will be issued for patients to record exercise conditions and related exercise data, encouraged to exercise regularly and health education materials pushed by cardiovascular nurses.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Moderate-intensity continuous training
Description: Using routine postoperative care and follow-up, establish WeChat group as contact for postoperative follow-up, no adverse events after 2 weeks of adaptive exercise training and voluntary participants, patients exercise prescription for 12 weeks, 30-40 minutes, including 5 minutes of warm-up and cooling-off period of the last 5 minutes, during exercise intensity is 70-75% maximum heart rate reserve. The warm-up and cooling-off periods can be performed by stretching, flexibility exercises (i. e., neck, shoulders, upper back, hips, and ankles), and medium to low intensity (50-70% heart rate reserve). Specific exercise logs will be issued for patients to record exercise conditions and related exercise data, encouraged to exercise regularly and pushed health education materials by cardiovascular nurses.
Study: NCT05973890

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WhatsApp
Description: Participants assigned to the WhatsApp arm will receive messages, audios, images and videos in a moderated, closed WhatsApp group over a 14-month duration. The messages aim to motivate blood donation, encourage participants to discuss their blood donation experiences, and allow them to share their motivations for donating blood.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: docudrama
Description: Participants randomized to this arm will meet three times (Month 2; Month 5 and Month 10), in a group setting, during the intervention. Each group will have a maximum of 20-40 participants. This is a stand-alone activity, which is not associated with a donation event. During each meeting, participants will be asked to watch, in the group setting, an episode of drama, lasting 15 minutes. The docudrama on blood donation will address participant's concerns regarding blood donation and address common donor fears.
Study: NCT06556238

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine Metabolite Ratio
Description: Blood specimens will be drawn, in clinic, by clinical staff trained in blood collection (e.g., certified medical assistant, nurse). Through regular clinic procedures, lab staff will ship for processing to Quest. Quest uses liquid chromatography tandem mass spectrometry with a limit of detection of 2ng/ml for all analytes and will quantify NMR within 3-6 days of sample arrival. Samples will be consumed during testing. Results of NMR will be returned to primary care providers, and NMR-informed medication recommendations will be made to participants.
Study: NCT05997849

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile application
Description: A mobile application for the management of anxiety and depressive symptoms through self-applied emotional regulation tools.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile application
Description: A mobile application for the management of anxiety and depressive symptoms through self-applied emotional regulation tools.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile application
Description: A mobile application for the management of anxiety and depressive symptoms through self-applied emotional regulation tools.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mobile application
Description: A mobile application for the management of anxiety and depressive symptoms through self-applied emotional regulation tools.
Study: NCT05153811

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counseling
Description: Brief counseling including personalized feedback on breath alcohol concentration, cognitive task performance and physical functioning

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counseling
Description: Brief counseling including personalized feedback on breath alcohol concentration, cognitive task performance and physical functioning

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mHealth
Description: Participants will engage with an application designed to gamify drinking reduction.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counseling
Description: Brief counseling including personalized feedback on breath alcohol concentration, cognitive task performance and physical functioning.
Study: NCT05099965

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: CMV-MVA Triplex
Description: 5 x 108 plaque-forming unit (pfu) ±0.5 x 108 pfu of MVA Vaccine

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 7.5% Lactose in phosphate-buffered saline \[PBS\]
Study: NCT06605976

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DAX CoPilot Group
Description: Participants in this group were given a license for DAX CoPilot and asked to use it for clinical documentation.
Study: NCT05209451

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Digital, evidence-based behavioral health program for smoking cessation
Description: Remotely delivered, 12-week smoking cessation program delivered through the patient portal. The program will deliver a smoking cessation intervention that links study participants to tailored, interactive and effective evidence-based smoking cessation resources.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital, evidence-based behavioral health program for smoking cessation
Description: Remotely delivered, 12-week smoking cessation program delivered through the patient portal. The program will deliver a smoking cessation intervention that links study participants to tailored, interactive and effective evidence-based smoking cessation resources.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital, evidence-based behavioral health program for smoking cessation
Description: Remotely delivered, 12-week smoking cessation program delivered through the patient portal. The program will deliver a smoking cessation intervention that links study participants to tailored, interactive and effective evidence-based smoking cessation resources.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bluetooth enabled iPad
Description: Bluetooth enabled iPad with data plan coverage that provides a personal Wi-Fi (Internet) hot spot for all home devices and allows for up to 64 GB of cellular data.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coaching Support
Description: Six coaching calls, 15-20 minutes each in duration. The research coach will use motivational interviewing and goal setting to enhance the participant's technology access and use and digital literacy.
Study: NCT06607250

Intervention type: RADIATION
Intervention: MRI
Description: All enrolled patients underwent multiparametric magnetic resonance imaging, encompassing T2-weighted imaging (T2WI) and magnetic resonance diffusion-weighted imaging (DWI), in the coronal, sagittal, and axial planes.
Study: NCT06606392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Biodex balance system
Description: The Biodex Balance System has a wide range of clinical applications and provides objective measures from testing that can be used to establish progressions and discharge criteria, as well as be part of a comprehensive Fall Risk Assessment or Fall Screening Program. Balance ability can be assessed either statically or dynamically, as well as bilaterally and unilaterally. It also allows for bilateral comparisons between involved and uninvolved limbs.

Intervention type: OTHER
Group type: OTHER
Intervention: Short Foot Exercise
Description: Short foot exercise is used as a therapeutic exercise to strengthen intrinsic foot muscles and used as training to create an MLA. It helps improve the balance in functional movement of FF subjects, decreases navicular drop (ND) through intrinsic muscle activation, supports navicular stability, and improves balance

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Short Foot Exercise
Description: Short foot exercise is used as a therapeutic exercise to strengthen intrinsic foot muscles and used as training to create an MLA. It helps improve the balance in functional movement of FF subjects, decreases navicular drop (ND) through intrinsic muscle activation, supports navicular stability, and improves balance
Study: NCT06608446

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telerehabilitation
Description: The telerehabilitation intervention will begin from 10 days post-surgery, the operation will be carried out at home from Monday to Friday via the TeleHab device (Vald Performance) up to 2 months after the surgery.~Exercises for ROM recovery and strength recovery will be carried out three days a week and only exercises for ROM recovery will be carried out two days a week. The progression of the exercises will be carried out taking into account the pain and fatigue recorded by the patient at the end of each exercise session.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care
Description: Standard care intervention follow the usual treatment according to current clinical practice, no structured physiotherapeutic interventions will be carried out. It consists of the delivery of two booklets, with the aim of informing and educating, regarding the most frequent complications after breast cancer surgery and how to avoid its possible onset through the demonstration of exercises to be carried out at home, self-massage techniques for the scar, behaviors and lifestyle to be adopted immediately after surgery.
Study: NCT06607562

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic group
Description: The experimental phase of this study lasted for 56 days, during which we will measure participants' liver function, such as alanine aminotransferase (ALT) at baseline and end.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo group
Description: The experimental phase of this study lasted for 56 days, during which we will measure participants' liver function, such as alanine aminotransferase (ALT) at baseline and end.
Study: NCT06608342

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous hematopoietic stem cell transplantation combined with CD19-CART
Description: Autologous CD19-CAR T cells were transfused +7 days after autologous hematopoietic stem cell transplantation
Study: NCT06264817

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MOBIDERM Autofit Armsleeve
Description: In the intervention group, during the intensive phase, patients wear day and night MOBIDERM AUTOFIT during 3 weeks.~During the maintenance phase, patients wear usual compression sleeve during the day and MOBIDERM Autofit Armsleeve at night during 5 weeks

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Compressive bandaging
Description: In the control group, during the intensive phase, patients wear compressive bandaging day and night-time, according to the usual practice during 3 weeks.~During the maintenance phase, patients wear usual compression sleeve during the day and self bandages at night during 5 weeks
Study: NCT06677164

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Gluteus Maximus strengthening exercise
Description: Maximus strengthening exercise for eight weeks using weight progression tools either elastic band or sand weight by assuming two modes of exercises (clamshell exercise, prone hip extension) with stretching exercise (hamstring, gastrocnemius, soleus, and plantar fascia) 2 sessions per week for 8 weeks

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: high-intensity laser therapy
Description: A 3-phase treatment program will be performed in each session on the plantar fascia area. Treatment of trigger points in phase 1 and 2 by using power of 9 watts, E2C mode for 6 minute of 2 phases. The draining and vascularization-promoting application involve the whole foot sole, starting from the heel area in phase three by using power of 9 watts, CW mode with energy of 100J/cm2.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high-intensity laser therapy
Description: A 3-phase treatment program will be performed in each session on the plantar fascia area. Treatment of trigger points in phase 1 and 2 by using power of 9 watts, E2C mode for 6 minute of 2 phases. The draining and vascularization-promoting application involve the whole foot sole, starting from the heel area in phase three by using power of 9 watts, CW mode with energy of 100J/cm2.
Study: NCT06275984

Intervention type: OTHER
Group type: OTHER
Intervention: online CPR-AED training
Description: The online CPR-AED training consists of successfully completing the online training course. To access the course, interested persons must register on a Moodle environment platform, with free and open access, through the following link: https://register.magnore.com/registre-curs-de-reanimacio -cardiopulmonary-dea/~Online training takes 3-4h and the participant will have access for 1 month (7x24h).
Study: NCT06483256

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: radiographic control
Description: Radiographic study with standard projections (AP and LL) is used to assess any signs of anchor loosening and/or presence of heterotopic ossifications (which can restrict movement and is one of the main complications).
Study: NCT06315179

Intervention type: DIAGNOSTIC_TEST
Intervention: Esophagogastroduodenoscopy (EGD) with biopsy
Description: Esophagogastroduodenoscopy (EGD) is a test procedure to examine the lining of the esophagus, stomach, and first part of the small intestine.

Intervention type: DIAGNOSTIC_TEST
Intervention: Esophagogastroduodenoscopy (EGD) with biopsy
Description: Esophagogastroduodenoscopy (EGD) is a test procedure to examine the lining of the esophagus, stomach, and first part of the small intestine.
Study: NCT06040099

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab IV (intravenous)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transarterial Radioembolization (TARE)
Description: Yttrium 90 glass microspheres will be administered
Study: NCT06109467

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neratinib
Description: All participants will take 240mg neratinib by mouth every day beginning cycle 1 day 1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: All participants will receive standard dosing (6mg/kg loading dose, 4 mg/kg subsequent doses) of Trastuzumab by IV infusion day 1 of each 2 week cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: All participants will receive 85mg Oxaliplatin by IV infusion day 1 of each 2 week cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-Fluorouracil + leucovorin
Description: All participants will receive 400 mg/m\^2 5-Fluorouracil (5FU)+ 400 mg/m\^2 leucovorin day 1 of each 2 week cycle; 5FU continuous infusions on days 1 and 2 of each 2 week cycle. (5FU + leucovorin may be eliminated from regimen per PI discretion)
Study: NCT05473338

Intervention type: DIAGNOSTIC_TEST
Intervention: Stool and blood samples
Description: fecal microbiome and metabolomics, as well as metabolites in plasma

Intervention type: DIAGNOSTIC_TEST
Intervention: Stool and blood samples
Description: fecal microbiome and metabolomics, as well as metabolites in plasma

Intervention type: OTHER
Intervention: Physical examination
Description: physical examination performed by a physician to confirm CRPS diagnosis and assess patient's eligibility to participate in the study. The exam will include skin temperature measured using a laser/infrared skin thermometry.

Intervention type: OTHER
Intervention: Questionnaires
Description: Questionnaires measuring pain level, sleep, mood and diet parameters.

Intervention type: OTHER
Intervention: Questionnaires
Description: Questionnaires measuring pain level, sleep, mood and diet parameters.
Study: NCT06109467

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: All participants will receive 400mg Pembrolizumab by IV infusion day 1 of every 3rd 2 week cycle.
Study: NCT06647069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DR-0201
Description: DR-0201 is a bispecific antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DR-0201
Description: DR-0201 is a bispecific antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DR-0201
Description: DR-0201 is a bispecific antibody
Study: NCT05792371

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: induced membrane technique
Description: Masquelet technique, also called an induced membrane technique (IMT), was first introduced to treat critical size bone defect up to 25 cm in 1986 by Pr. Alain Charles Masquelet et al. IMT is a two-stage surgical operation that recently provides a more popular option for the treatment of critical size bone defect as well as fracture nonunion. Basically, first stage of IMT comprises the implantation of a polymethylmethacrylate (PMMA) cement spacer loaded with antibiotics into defect site. During 6 to 8 weeks, this spacer induces the formation and maturation of a thin layer called induced membrane surrounding it via a foreign body immune response. In stage II, the spacer is carefully removed while keeping induced membrane at the fracture site, autologous bone graft is then performed to provoke bone healing.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone graft (Stage II of IMT)
Description: Bone graft is only performed in this group to provoke bone healing, as same as demonstrated in the stage II of IMT.
Study: NCT04130126

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Taking cold showers
Description: Showering behaviour
Study: NCT06045026

Intervention type: OTHER
Group type: OTHER
Intervention: Stannous fluoride
Description: Anti-sensitivity toothpaste containing 0.454% Stannous Fluoride
Study: NCT05516706

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic stretching
Description: Participants in this group performed a 10 minutes warm-up followed by 15 minutes of dynamic stretching exercises which included arm cross-over, scapular scaption, upper body twist walking lunges, cat and cow pose, and rotator cuff movements.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Plyometric push up
Description: Participants in this group performed 10 minutes of warm-up followed by 15 minutes of plyometric push training which included one-arm push-ups and depth push up
Study: NCT05486468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Yutiq 0.18 MG Drug Implant
Description: YUTIQ ® (fluocinolone acetonide intravitreal implant) 0.18 mg, for intravitreal injection

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Injection
Description: Sham injection