TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06651411

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STARS (Scalable Technology for Adolescents and youth to Reduce Stress)
Description: The intervention is a chatbot-based stress management intervention developed by the World Health Organization (WHO). It consists of 10 sessions, which include: Introduction (1), Psychoeducation (2), Emotion Regulation (3, 4), Behavior Activation (5, 6), Managing Problems (7), Thought Challenging (8, 9), and Relapse Prevention (10). Each session consists of psychoeducation and exercise parts. Trained e-helpers contact participants to support them individually weekly.~The effect of the intervention will be compared against a control group that receives basic psychoeducation. The intervention is provided in Lithuanian.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Basic psychoeducation
Description: Basic psychoeducation includes basic information on stress management.
Study: NCT05124782

Intervention type: OTHER
Intervention: Rheumatoid Arthritis Impact of Disease questionnaire
Description: Rheumatoid Arthritis Impact of Disease questionnaire
Study: NCT06062069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-868
Description: CT-868 is an investigational medication administered subcutaneously via a pre-filled pen injector device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-868
Description: CT-868 is an investigational medication administered subcutaneously via a pre-filled pen injector device.
Study: NCT05593432

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib cream
Description: Ruxolitinib cream is a topical formulation applied as a thin film to affected areas.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vehicle cream
Description: Vehicle cream is matching in appearance to ruxolitinib cream and is to be applied in the same manner as ruxolitinib cream.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle cream
Description: Vehicle cream is matching in appearance to ruxolitinib cream and is to be applied in the same manner as ruxolitinib cream.
Study: NCT06327152

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine
Description: Infants randomized to receive caffeine will continue to receive caffeine at the current weight-based dose (which is the standard of care maintenance dose of 10-15 mg/kg/day) given every 24 hours. The weight-based dose calculated using the weight at the time of enrollment will be the weight-based dose used for the duration of the study. The dose will be weight adjusted every 7 days, starting on the day of enrollment. Caffeine will be given enterally, via nasogastric tube or by mouth.~The study drug (caffeine) will be administered for a maximum of 4 weeks. The study drug will be discontinued after 4 weeks or when the infant reaches Step 4 of our institution's oral feeding protocol (oral feeding 6 times per day), whichever comes first. The study drug will also be discontinued if the open-label maintenance caffeine is started by the clinical team based on clinical indications.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sterile Water Placebo
Description: Infants randomized to the placebo group will be given sterile water at an equivalent volume to the volume if caffeine were to be given, using the previous weight-based caffeine dose. The placebo will be given every 24 hours. The dose/volume will be weight adjusted every 7 days, starting on the day of enrollment. The placebo will be given enterally, via nasogastric tube or by mouth.~The placebo will be administered for a maximum of 4 weeks. The placebo will be discontinued after 4 weeks or when the infant reaches Step 4 of our institution's oral feeding protocol (oral feeding 6 times per day), whichever comes first. The placebo will also be discontinued if the open-label maintenance caffeine is started by the clinical team based on clinical indications.
Study: NCT05574153

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac MRI
Description: Participants will undergo an oxygenation-sensitive cardiac MRI and, during the scan, perform a vasoactive breathing maneuver composed of a period of paced hyperventilation followed by a voluntary maximal breath hold.

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac MRI
Description: Participants will undergo an oxygenation-sensitive cardiac MRI and, during the scan, perform a vasoactive breathing maneuver composed of a period of paced hyperventilation followed by a voluntary maximal breath hold.
Study: NCT06247969

Intervention type: DEVICE
Intervention: endotracheal tube
Description: Endotracheal Tube (ETT) is a flexible plastic tube that is inserted through the mouth or nose into the trachea to establish an artificial airway.
Study: NCT04635176

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone)
Description: real iPACK block with 20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sham iPACK block with 20ml normal saline
Description: Sham iPACK block with 20 ml Normal saline
Study: NCT00934609

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Endurance training
Description: 45 min ergometer cycling at the ventilatory anaerobic threshold 4 times per week for 12 weeks
Study: NCT06062069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-868
Description: CT-868 is an investigational medication administered subcutaneously via a pre-filled pen injector device.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CT-868 Pen Injector
Description: The CT-868 pen injector is a multi-dose, single-participant, disposable pen.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CT-868 Pen Injector
Description: The CT-868 pen injector is a multi-dose, single-participant, disposable pen.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CT-868 Pen Injector
Description: The CT-868 pen injector is a multi-dose, single-participant, disposable pen.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: CT-868 Pen Injector
Description: The CT-868 pen injector is a multi-dose, single-participant, disposable pen.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: : CT-868 Pen Injector, Placebo
Description: The placebo pen injector is identical and contains the same ingredients except for CT-868.
Study: NCT05582603

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CCT Long COVID
Description: A 15-day training protocol in which every 48 hours participants' complete a series of different cognitive tasks in the form of games selected among a pool of 12 games from CogniFit (CogniFit Inc., San Francisco, USA) whose difficulty level is tailored to each individual by the a patented Individualized Training System™ (ITS) software that automatically chooses the activities and difficulty levels for each person in every session.
Study: NCT05102591

Intervention type: DRUG
Group type: OTHER
Intervention: Ketorolac
Description: Intervention in syringe for target dose of 0.5 mg/kg, maximum 30 mg of ketorolac (1 mL), and administer as a direct IV push over 1-5 minutes

Intervention type: DRUG
Group type: OTHER
Intervention: Metoclopramide
Description: Intervention in 50 mL mini bag of normal saline (0.9% NaCl) for target dose of 0.15 mg/kg, maximum 10 mg of metoclopramide (2 mL), and administer as infusion over 15-30 minutes

Intervention type: DEVICE
Group type: OTHER
Intervention: Active Remote Electrical Neuromodulation Device
Description: The REN device is a battery-powered, wirelessly controlled neuromodulation device that attaches via armband to the upper arm. The REN device is controlled by a smartphone application and administers electrical stimulation to the local C and Aδ nociceptive sensory nerves of the upper arm. This stimulation is achieved using a symmetrical, biphasic, square pulse, modulated at a frequency between 100-120 Hz. Each pulse has a width of 400 µs and the user, via the smartphone application, can adjust the output current to apply a maximum of 40 mA. Each stimulation session occurs over 45 minutes and each device can administer up to 12 stimulation sessions.

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: 0.9% NaCl will be administered to participants through IV in identical dosages, methods, and duration as the ketorolac and metoclopramide interventions described above.

Intervention type: DEVICE
Group type: OTHER
Intervention: Sham Remote Electrical Neuromodulation Device
Description: The sham REN device is identical to the active REN device but the stimulation parameters are different, administering a modulated symmetrical biphasic square electrical pulse, modulated frequency of \~0.083 Hz and a modulated pulse width of 40-550 µ. These sham parameters are designed to induce a sensation that will be perceptible to participants, similar to stimulation from the active REN device, but at a frequency that is low enough so as to not modulate the nociceptive sensory nerves.
Study: NCT04814927

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Copper IUD
Description: Participants randomized to Copper IUD will receive Paragard IUD at Visit 2.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Etonogestrel implant
Description: Participants randomized to ETG implant will receive the implant at Visit 2.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levonorgestrel IUS
Description: Participants randomized to LNG intrauterine system will receive the IUS at Visit 2.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DMPA Sub-cutaneous
Description: Participants randomized to DMPA SC will receive the injection at Visit 2.
Study: NCT05602337

Intervention type: OTHER
Intervention: Observational Study Only
Description: Non-invasive Skin Sampling
Study: NCT04680585

Intervention type: OTHER
Group type: OTHER
Intervention: Enhanced Usual Care
Description: A standardized handout with information on what treatment options might be useful to start with based on EPDS score and stage of pregnancy or postpartum.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enhanced Usual Care
Description: A standardized handout with information on what treatment options might be useful to start with based on EPDS score and stage of pregnancy or postpartum.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MOVIN Care Platform
Description: Virtual collaborative care intervention with a stepped care approach in which a care coordinator directs participants to one or more evidence-based virtual interventions as appropriate.
Study: NCT06169670

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Viality
Description: Viality is a lipoaspirate wash system designed to be used in the operating room in conjunction with, and attached to, a user-provided liposuction cannula, a vacuum source, and a waste canister.~Viality is to be used to filter and wash aspirated, harvested autologous adipose tissue for aesthetic body contouring. The system should be used with a legally marketed vacuum or aspirator apparatus as a source of suction. If harvested fat is to be re-implanted, the harvested fat is to be used without any additional manipulation. Viality is not intended to process autologous adipose tissue other than for aesthetic body contouring uses.
Study: NCT06558864

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subiculum RF-TC
Description: SEEG implantation after evaluation, record the interictal and ictal EEG, and perform Subiculum RF-TC.
Study: NCT06330142

Intervention type: OTHER
Group type: OTHER
Intervention: Participation in 10 horse-assisted therapy sessions
Description: supporting children and teenagers undergoing radiotherapy with a horse-assisted therapy approach
Study: NCT06486298

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vacuum Drain and Passive Drain insertion at abdominoplasty surgery
Description: Compare the subcutaneous collection with Vacuum Drain and Passive Drain insertion at abdominoplasty surgery

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vacuum Drain and Passive Drain insertion at abdominoplasty surgery
Description: Compare the subcutaneous collection with Vacuum Drain and Passive Drain insertion at abdominoplasty surgery
Study: NCT05222477

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: pelvic floor exercise
Description: pelvic floor exercises(intervention) will be applied for patients with nocturia and type 2 DM for 6 weeks, 3 times/week
Study: NCT04980547

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUMED® Scapholunate Repair System Group
Description: To address the technical difficulties associated with the RASL procedure, Dr. Mel Rosenwasser developed an external over-the-top jig that in theory enables accurate and easy scapholunate-axis screw placement. The Acumed Scapholunate Repair System was designed treat patients with acute or chronic, static or dynamic scapholunate instability in the absence of significant capitolunate osteoarthritis, scapholunate ligament repair, scapholunate reduction, lunotriquetral ligament repair, lunotriquetral reduction, and carpal instability. This new Scapholunate Repair System features a targeting guide designed to enable the surgeon to reproducibly place the implant in optimal position. The implant allows physiologic intercarpal scapholunate rotation by means of a free rotation design. The procedure can forestall progressive osteoarthritis and the need for secondary salvage procedures.
Study: NCT06201143

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BREATHING EXERCISE AND MOBILIZATION TRAINING
Description: After cesarean mobilization and breathing exercise training, the number of breathing exercises performed and the duration of mobilization will be recorded. Thus, the effectiveness of the training will be examined in detail.
Study: NCT05602337

Intervention type: OTHER
Intervention: Observational Study Only
Description: Non-invasive Skin Sampling

Intervention type: OTHER
Intervention: Observational Study Only
Description: Non-invasive Skin Sampling
Study: NCT05602337

Intervention type: OTHER
Intervention: Observational Study Only
Description: Non-invasive Skin Sampling

Intervention type: OTHER
Intervention: Observational Study Only
Description: Non-invasive Skin Sampling

Intervention type: OTHER
Intervention: Observational Study Only
Description: Non-invasive Skin Sampling
Study: NCT06201143

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: KINESIOLOGICAL TAPING + BREATHING EXERCISE AND MOBILIZATION TRAINING
Description: It will be the first study to use kinesiotaping, breathing exercise and mobilization training together.
Study: NCT06254274

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RAY1225
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RAY1225
Description: Administered SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study: NCT05077761

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active High-intensity laser therapy
Description: High-intensity laser therapy will be used in the contact method, with the laser beam irradiated over the hamstring muscle. Dosage and parameters for the laser will be calculated.~Parameters-~1. Wavelength- 980 nm~2. Intensity/Power density- 3W/cm2~3. Emission mode- Continuous Emission~4. Energy (Joules)- 490 J~5. Irradiation time- 70 Sec on each point~6. Peak power- 15 Watt~7. Irradiation points- 09

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham High-intensity laser therapy
Description: Sham High-intensity laser therapy will be used in the contact method, without the laser beam irradiation over the hamstring muscle.
Study: NCT05085210

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial random noise stimulation (tRNS)
Description: noninvasive current stimulation for 20 - 30 minutes stimulation on visual cortex (electrodes on surface of scalp, positioned O1 / O2 on EEG cap). 1mA max amplitude noise stimulation, frequencies from 100 Hz - 640 Hz.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial random noise stimulation (tRNS)
Description: noninvasive current stimulation for 20 - 30 minutes stimulation on visual cortex (electrodes on surface of scalp, positioned O1 / O2 on EEG cap). 1mA max amplitude noise stimulation, frequencies from 100 Hz - 640 Hz.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial random noise stimulation (tRNS)
Description: noninvasive current stimulation for 20 - 30 minutes stimulation on visual cortex (electrodes on surface of scalp, positioned O1 / O2 on EEG cap). 1mA max amplitude noise stimulation, frequencies from 100 Hz - 640 Hz.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Computer Based Visual Training
Description: Dynamic visual stimuli are presented on specific locations of the visual field. Participant holds fixation on center of screen during presentation of visual stimuli. Participants will be presented with multiple trials of a motion discrimination task. Training will be performed for 2 weeks (10 consecutive weekdays), 30 minutes each day.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Computer Based Visual Training
Description: Dynamic visual stimuli are presented on specific locations of the visual field. Participant holds fixation on center of screen during presentation of visual stimuli. Participants will be presented with multiple trials of a motion discrimination task. Training will be performed for 2 weeks (10 consecutive weekdays), 30 minutes each day.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: 20-30 minutes sham stimulation on visual cortex. Participants receive identical setup to real stimulation. The device provides a short ramp on period to simulate the feeling of real stimulation at the start but no current is delivered otherwise.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham stimulation
Description: 20-30 minutes sham stimulation on visual cortex. Participants receive identical setup to real stimulation. The device provides a short ramp on period to simulate the feeling of real stimulation at the start but no current is delivered otherwise.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Based Visual Training
Description: • Dynamic visual stimuli are presented on specific locations of the visual field. Participant holds fixation on center point within the VR headset during presentation of visual stimuli. Participants will be presented with multiple trials of a motion discrimination task. Training will be performed for 2 weeks (10 consecutive weekdays), 30 minutes each day.
Study: NCT06172543

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Creatine Monohydrate
Description: Participants were assigned to ingest a single serving daily of either A) a 25-gram dose of whey protein isolate + 25-gram dose of carbohydrate powder (ProCarb); or B) a 25-gram dose of Whey Protein Isolate + 25-gram dose of carbohydrate powder + 5-gram dose of creatine monohydrate (Creatine) for a 17-21-day period.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: A 25-gram dose of whey protein isolate + 25-gram dose of carbohydrate powder (ProCarb)
Study: NCT05222477

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Abdominal muscles exercise
Description: abdominal exercises (intervention) will be applied for patients with nocturia and type 2 DM for 6 weeks, 3 times/week
Study: NCT06018532

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PRESAGE CARE
Description: PRESAGE Care informations from the application will be processed by the PRESAGE Care algorithm in real time, and may generate alerts indicating an increased risk of hospitalization or emergency department visits within 7 to 14 days. These alerts will be transmitted to a Care Manager platform, who will analyse the situation, initiate the healthcare intervention and coordinate its implementation. In practice, a care manager (coordinating nurse) will process the alert and carry out an initial assessment of the beneficiary's situation, using the information feedback platform, then by telephone, contacting the older adults beneficiary and the relative. The care manager may or may not implement preventive measures. If necessary, the patient may be offered an outpatient medical consultation, a home visit, a consultation with his or her GP and/or social or paramedical interventions.
Study: NCT04899089

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Training
Description: The computerized training exercises and brain games help stimulate cognitive functions while providing real-time monitoring on the evolution of participants' skills.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Trivia Training
Description: The computerized trivia training asks participants to answer general questions related to pop culture, science, geography, etc. Participants can use online sources to search for answers and will be provided feedback on their accuracy.
Study: NCT05931315

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CaroRite™
Description: One capsule to be taken immediately post-dinner / with dinner

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One capsule to be taken immediately post-dinner / with dinner
Study: NCT05967091

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Targeted Lung Denervation
Description: Targeted Lung Denervation (TLD) is a bronchoscopically guided, minimally invasive procedure using the Ryme Medical Lung Denervation System
Study: NCT06189950

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intracranial stent for wide-necked aneurysms
Description: Intracranial stent for wide-necked aneurysms

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intracranial stent for wide-necked aneurysms
Description: Intracranial stent for wide-necked aneurysms
Study: NCT05049720

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Defibrillation using the Extravascular ICD
Description: VT/VF induction attempted for defibrillation testing, as well as requisite electrical testing.
Study: NCT05608655

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DKutting LL balloon
Description: After pre-dilation balloon is used (if any), DKutting LL balloon is used as final dilatation balloon before Stent implantation or Drug Coated Balloon deployment

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Chocolate balloon
Description: After pre-dilation balloon is used (if any), Chocolate balloon is used as final dilatation balloon before Stent implantation or Drug Coated Balloon deployment
Study: NCT06097780

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NestaCell®
Description: Human Dental Pulp Stem Cells (hDPSCs).

Intervention type: GENETIC
Group type: PLACEBO_COMPARATOR
Intervention: NestaCell®
Description: Human Dental Pulp Stem Cells (hDPSCs).