TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04591210

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Angiotensin converting enzyme inhibitor
Description: The study recommends physicians to select an ACEi with proven benefit in cardiovascular diseases such as perindopril, ramipril or enalapril. Lab values will be obtained during baseline. The patient will be followed by the physician clinically, with recommended laboratory testing in one week, including renal function, potassium assessment, and dose adjustments as appropriate.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Angiotensin II Receptor Blockers
Description: The study recommends physicians to select evidence-based ARBs such as candesartan or valsartan or losartan. Lab values will be obtained during baseline. The patient will be followed by the physician clinically, with recommended laboratory testing in one week, and dose adjustments as appropriate.
Study: NCT05443971

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study: NCT05973201

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality headset
Description: A HEALTHY MIND® brand VR headset is dedicated to the study. The kit includes a noise-reducing audio headset, a face mask diffusing the visual part, a touchscreen tablet connected to the two VR headset systems, and a microphone connected to the tablet.~The available software allows patients to choose between 5 natural environments in which a hypnotic speech is broadcast, available in several languages (French, English, Spanish, Russian, Arabic).
Study: NCT06376682

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CT-guided bone percutaneous procedure
Description: The EPIONE device is a user controlled, stereotactic accessory intended to assist in the planning and manual advancement of one or more instruments, as well as in verification of instrument position during Computed Tomography (CT) guided percutaneous procedures (thermal ablation, bone consolidation, biopsy procedures).
Study: NCT05658328

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SHARP - Physical and social activity
Description: Technology-enabled neighborhood walking 3x/week for 16 weeks with conversational reminiscence

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SHARP - Physical and social activity
Description: Technology-enabled neighborhood walking 3x/week for 16 weeks with conversational reminiscence
Study: NCT05480228

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NRD135SE.1
Description: The double-blind treatment phase is up to 13 weeks.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A matching placebo will be taken for up to 13 weeks.
Study: NCT05775211

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Intrauterine administration of PBMC immunomodulated with IFNt
Description: Standard density gradient centrifugation will be performed to obtain autologous PBMC from patients' peripheral blood (9 ml). Isolated cells will be suspended in RPMI 1640 supplemented with 10% HSA (human serum albumin) and incubated in the presence of 500 IU/ml IFNt for 24 h at 37˚C. The cultured cell suspension will be introduced into the uterine cavity via a catheter.
Study: NCT06098690

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally Tailored Multimedia Psychoeducational HPV Intervention
Description: The culturally tailored multimedia psychoeducational intervention will involve audio and visual content and will be delivered in a bilingual fashion (English and Spanish) among adults 18-45 years-old.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General HPV Multimedia Psychoeducational Control Group
Description: The general/publicly available multimedia intervention will involve audio and visual content and will be delivered in a bilingual fashion (English and Spanish) among adults 18-45 years-old.
Study: NCT06565468

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cold water immersion pool.
Description: Participants will complete a session of cold-water immersion within one hour of finishing the last training session of the day. Cold water immersion will consist of ten minutes of submersion to the neck in a cold-water tub with a target temperature of 55 degrees Fahrenheit (daily temperatures will be recorded at the time of each session). The acceptable range for the cold water immersion protocol will be from 53-57 degrees Fahrenheit. The immersion process will not be completed if the temperature of the water is outside of this range. Participants will complete five sessions per week, with a total of 10 sessions to be completed over the 14-day intervention.
Study: NCT05105321

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berberine
Description: The tablet of berberine and placebo are both coated with white sugar and had the same appearance. Berberine tablet will be orally taken with a dose of 500mg twice daily

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy lifestyle intervention
Description: Healthy lifestyle intervention will be launched according to the Chinese guidelines on prevention of cardiovascular and metabolic diseases by Chinese Preventive Medical Association in 2019, including health lectures, health information promotion, health manual and so on.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Healthy lifestyle intervention
Description: Healthy lifestyle intervention will be launched according to the Chinese guidelines on prevention of cardiovascular and metabolic diseases by Chinese Preventive Medical Association in 2019, including health lectures, health information promotion, health manual and so on.
Study: NCT05592301

Intervention type: DIAGNOSTIC_TEST
Intervention: Diffusion-weighted Magnetic Resonance Imaging (DW-MRI)
Description: The Diffusion-weighted Magnetic Resonance Imaging (DW-MRI) is used to diagnose perioperative stroke.

Intervention type: DIAGNOSTIC_TEST
Intervention: Transcranial Doppler (TCD)
Description: Used to diagnose PFO

Intervention type: DIAGNOSTIC_TEST
Intervention: Transthoracic Echocardiogram (TTE)
Description: Used to diagnose PFO.
Study: NCT05452252

Intervention type: DIAGNOSTIC_TEST
Intervention: functional mandibular evaluation
Description: Active mandibular movements including depression, protrusion, and left-right deviation, facial anthropometry was measured on facial shape on photograph, and phenotype and asymmetry

Intervention type: DIAGNOSTIC_TEST
Intervention: functional mandibular evaluation
Description: Active mandibular movements including depression, protrusion, and left-right deviation, facial anthropometry was measured on facial shape on photograph, and phenotype and asymmetry
Study: NCT04892186

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Myo-inositol
Description: 30 women with polycystic ovary syndrome and insulin resistance or glucose intolerance will used myo-inositol 2g + folic acid 200mcg twice daily for 6 months, having a re-evaluation every 3 months.~Evaluation will be made by transvaginal ultrasound, abdominal ultrasound, inflammatory tests, hormonal tests, glycemic curve with insulin curve, lipid profile, body mass index, evaluation of abdominal and hip circumference.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: 30 women with polycystic ovary syndrome and insulin resistance or glucose intolerance will used metformin 850 mg twice a day for 6 months, having a re-evaluation every 3 months.~Evaluation will be made by transvaginal ultrasound, abdominal ultrasound, inflammatory tests, hormonal tests, glycemic curve with insulin curve, lipid profile, body mass index, evaluation of abdominal and hip circumference.
Study: NCT05424185

Intervention type: BEHAVIORAL
Intervention: different type of scapular dyskinesis
Description: rapid arm elevation to see the different of EMG rise and force development

Intervention type: BEHAVIORAL
Intervention: different type of scapular dyskinesis
Description: rapid arm elevation to see the different of EMG rise and force development

Intervention type: BEHAVIORAL
Intervention: different type of scapular dyskinesis
Description: rapid arm elevation to see the different of EMG rise and force development

Intervention type: BEHAVIORAL
Intervention: different type of scapular dyskinesis
Description: rapid arm elevation to see the different of EMG rise and force development
Study: NCT05032547

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Therapist-supported digitally delivered transdiagnostic emotion regulation treatment
Description: Please see description of experimental arm (arm one)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Therapist-supported digitally delivered supportive treatment
Description: Please see description of active comparator arm (arm two)
Study: NCT06155240

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Therapeutic yoga
Description: Yoga interventions include yoga poses, breathing, and meditation
Study: NCT06056765

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Minilith, Storz, Swiss
Description: shock waves
Study: NCT05351710

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exposure-Based Treatment for Perfectionism
Description: Three tasks focused on exposures are completed. Each treatment session is approximately twenty minutes.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stress Management
Description: Videos focused on education about healthy habits and relaxation. Each session is approximately twenty minutes.
Study: NCT05287607

Intervention type: DIAGNOSTIC_TEST
Intervention: Urine sample for carbonic anydrase (I) levels
Description: Point of care diagnostic device used routinely for non-invasive estimation of serum bilrubin level.
Study: NCT01590862

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Deep Brain Stimulator
Description: Medtronic Deep Brain Stimulation device turned on and off
Study: NCT05238415

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Psychological and Physiological Assessments
Description: About N = 60 patients admitted to the study receive a 3-day assessment (a further examination) at the Kiliani-Klinik Bad Windsheim which considers physical and psychological parameters relevant for the diagnosis of a Post-/ Long-COVID Syndrom.
Study: NCT06511687

Intervention type: BIOLOGICAL
Intervention: Nirsevimab
Description: Nirsevimab will be administered in a single dose at birth for newborn cohort and at the beginning of the campaign for the other cohorts under study

Intervention type: BIOLOGICAL
Intervention: Nirsevimab
Description: Nirsevimab will be administered in a single dose at birth for newborn cohort and at the beginning of the campaign for the other cohorts under study

Intervention type: BIOLOGICAL
Intervention: Nirsevimab
Description: Nirsevimab will be administered in a single dose at birth for newborn cohort and at the beginning of the campaign for the other cohorts under study
Study: NCT06504680

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Repair of flexor tendon injury zone ll using 8- strand
Description: Repair cut flexor zone ll using 8-strand with and without splinting the wrist
Study: NCT06617286

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD30 CAR T-cell
Description: After MAC and AutoHSCT patients will receive CD30+ CAR T-cells (Phase 1B dose level 1 - 1x108/m2 (max 2.5x108) or dose level 2 - 2x108/m2 (max 5.0 x108) 21-42 days after the AutoHSCT and the RP2D dose level obtained in the Phase IB part administered in the Phase II portion.
Study: NCT06631768

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Casual labor subsidy
Description: Eligible participants will be offered a voucher that can be redeemed for a set number of days of agricultural labor from casual laborers hired by local One Acre Fund offices. Casual laborers receive standard training in line with the trainings currently offered by the organization to participating farmers.
Study: NCT06712914

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MagPro X100 by MagVenture
Description: Participants will receive 5 session per day of TBS for 6 days (30 sessions total). Six treatment days have to occur within a 2 week period. Each session will be comprised of 1800 pulses, using a MagVenture MagPro X100.
Study: NCT06715514

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLP-1 Receptor Agonist
Description: Wegovy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: GLP-1 Receptor Agonist
Description: Wegovy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Menopausal Hormone Therapy
Description: Oestrogel and Utrogestan (in women with intact uterus)

Intervention type: DRUG
Group type: OTHER
Intervention: Menopausal Hormone Therapy
Description: Oestrogel and Utrogestan (in women with intact uterus)
Study: NCT06717490

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium sulphate
Description: In patients allocated to the MS group, a fixed dose of magnesium sulfate diluted in a fixed volume of natural saline will be administered intravenously.~Thromboelastometry will be performed pre and post magnesium administration.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Drug
Description: In patients allocated to the NS group, a fixed dose of natural saline will be administered intravenously, through a fixed volume of solution.~Thromboelastometry will be performed pre and post magnesium administration.
Study: NCT06716944

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture
Description: self-acupuncture
Study: NCT06718114

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: immediate urinary catheter removal
Description: Immediate urinary catheter removal indicates that the urinary catheter will be removed immediately after surgery.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: early removal of urinary catheter
Description: The urinary catheter will be kept after surgery and be removed within 48 hours after surgery.
Study: NCT06714968

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital
Description: After the pre-test application is completed, the students in the experimental group will be allowed to install the designed game application on their phones. After the installation process, students will be allowed to play the game for 2 weeks. After 2 weeks from the date of downloading the game, access to the game will be automatically blocked. After completing the application steps, when the student thinks that he/she is ready to apply the post-test, he/she will be able to perform the post-test application. In the post-test application, there will be no repeated return of the student to the questions or multiple answer submission. Two weeks after the application is completed, the knowledge test will be applied to the students again in order to objectively evaluate the learning. In this process, students will be prevented from accessing the application.
Study: NCT06716437

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation
Description: Patients will undergo a physiotherapy-led digitally-enabled prehabilitation program before lung resection surgery.~The intervention will be delivered through a mobile app and supported by tele-health and will consist of:~i) watching six educational videos embedded on the app on relevant topics to prepare for surgery, such as the importance of physical fitness, breathing exercises after surgery, and pain management.~ii) a physical activity coaching program to increase daily activity with feedback iii) a home-based, unsupervised exercise program consisting of 10 whole body strengthening exercises delivered in a video format iv) an inspiratory muscle training program using a hand-held device to be performed twice daily.
Study: NCT06716918

Intervention type: DRUG
Intervention: Corticosteroid Injection
Description: Participants who have received antenatal corticosteroids (betamethasone or dexamethasone) prior to cesarean section as part of their prenatal care.
Study: NCT06715280

Intervention type: DRUG
Group type: OTHER
Intervention: Riociguat (Adempas)
Description: Oral riociguat administered according to established dose-adjustment scheme. Riociguat will be administered starting at at 1mg three times per day. If patient systolic blood pressure maintains at 95mmHg or higher, the dose will be increased 0.5mg every 2 weeks up to a maximum dose 2.5mg three times per day over 8-week period
Study: NCT06715501

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: Cadonilimab is a PD-1/CTLA-4 bispecific antibody. The drug is administered at a fixed dose of 10mg/kg, intravenously (i.v.), on day 1, every 3 weeks (q3w), until disease progression or intolerable toxicity occurs, with a maximum treatment duration of 1 year.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: radiotherapy
Description: GTV is defined as visible lesions (GTVp: primary lesion; GTVn: metastatic lymph nodes), CTVp is defined as 3cm above and below the primary lesion, with 0.5cm outward expansion around the periphery, and CTVn is defined as 0.5cm outward expansion of GTVn; PTVp is an outward expansion of 0.5cm for CTVp, and PTVn is an outward expansion of 0.5cm for CTVn. Radiotherapy dose: DT50.4Gy/28f, once daily, 5 times a week

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: carboplatin, paclitaxel
Description: Induction chemotherapy: carboplatin 5AUC，q3w; Paclitaxel 135mg/m2,q3w. Simultaneous chemotherapy: 2AUC/W，total 5w; Paclitaxel 50mg/m2/w，total 5w
Study: NCT06716411

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Sterile insertive needles are applied by licensed, experienced practitioners.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture
Description: Sterile insertive needles are applied by licensed, experienced practitioners.
Study: NCT06713278

Intervention type: OTHER
Intervention: masseter muscle thickness measurement
Description: masseter muscle thickness measurement with ultrasonography

Intervention type: OTHER
Intervention: masseter muscle thickness measurement
Description: masseter muscle thickness measurement with ultrasonography

Intervention type: OTHER
Intervention: masseter muscle thickness measurement
Description: masseter muscle thickness measurement with ultrasonography

Intervention type: OTHER
Intervention: scales
Description: headache impact scale (HIT-6) Short SF-36 fibromyalgia total score widespread pain index symptom severity scale fibromyalgia impact questionnaire (FIQ)

Intervention type: OTHER
Intervention: scales
Description: headache impact scale (HIT-6) Short SF-36 fibromyalgia total score widespread pain index symptom severity scale fibromyalgia impact questionnaire (FIQ)

Intervention type: OTHER
Intervention: scales
Description: headache impact scale (HIT-6) Short SF-36 fibromyalgia total score widespread pain index symptom severity scale fibromyalgia impact questionnaire (FIQ)
Study: NCT06716489

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: Participants will undergo an aerobic exercise training program on a motorized treadmill at an intensity corresponding to 60-70% of their heart rate reserve (calculated by adding baseline heart rate to 60-70% of reserve heart rate). The program will last 16 weeks and will consist of three 1-hour, 10-minute sessions per week, divided into four phases: a 5-minute warm-up at an intensity below the target exercise heart rate (baseline + 30-40% of the reserve heart rate); a 50-minute main exercise session at the target exercise heart rate intensity; a 5-minute cool-down at an intensity below the target exercise heart rate; and a 10-minute relaxation and general stretching phase. This structured exercise protocol was designed to evaluate the effects of aerobic exercise on sensory perception, musculoskeletal alterations, and psychosocial factors in patients with migraine.
Study: NCT05022173

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Helmet Non-Invasive Ventilation
Description: The helmet interface is a modality which is used to deliver NIV to patients with respiratory failure. A transparent hood is placed over the entire head of the patient with a seal at the neck using a soft collar.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Facemask Non-Invasive Ventilation
Description: The facemask interface is a modality which is also used to deliver NIV to patients with respiratory failure. A large mask covering the mouth and nose is strapped to the patient's face to create a seal.
Study: NCT06472037

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: 10mg/kg，IV，D1，Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: 1000mg/m2，IV，D1、D8、D15，Q4W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab-Paclitaxel
Description: 125mg/m2，IV，D1、D8、D15，Q4W
Study: NCT06447766

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feeding Families Your Way Program
Description: Feeding Families Your Way is a video-based education program delivered by the University of Rhode Island Supplemental Nutrition Assistance Program - Education (SNAP-Ed).
Study: NCT05576025

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lifestyle intervention (cold exposure)
Description: Participants will undergo two cold exposures with different shivering intensities. Mild shivering is defined as energy expenditure increased by 1.5-fold compared to the resting metabolic rate. Moderate shivering is 2.5-fold increase in metabolic rate.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lifestyle intervention (cold exposure)
Description: Participants will undergo two cold exposures with different shivering intensities. Mild shivering is defined as energy expenditure increased by 1.5-fold compared to the resting metabolic rate. Moderate shivering is 2.5-fold increase in metabolic rate.
Study: NCT06389058

Intervention type: OTHER
Intervention: Recommendation for the diagnoses and treatment of Severe Asthma
Description: No intervention planned in this phase for the patients. Recommendations to be developed for healthcare and condition.
Study: NCT04959422

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active scheduling
Description: Active scheduling, tracking and rescheduling, if necessary.
Study: NCT05419869

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALTO-100 PO Tablet
Description: Two tablets daily
Study: NCT06544044

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Mindfulness' Self compassion
Description: session includes mindfulness exercises like breath awareness and body scans, self-compassion practices like self-kindness meditations, and emotional regulation strategies such as cognitive reappraisal and response modulation. Discussions focus on applying mindfulness and self-compassion to manage difficult emotions, improve interpersonal interactions, and reduce aggression. Home practice assignments encourage students to integrate mindfulness and self-compassion into their daily lives. The program curriculum is based on existing evidence-based interventions, including mindfulness-based stress reduction for teens.