TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05129397

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mom Power
Description: Virtual Mom Power is a manualized multi-family group intervention consisting of 10 virtual group + 2 individual sessions led by two masters-level co-facilitators. Virtual groups are 90 minutes, following a structured format via secure HIPAA compatible video platform. The curriculum includes 5 core components: (1) Attachment-Focused Parenting Education; (2) Self-Care; (3) Parenting Practice (4) Social Support; \& (5) Connection to Resources. Individual sessions combine motivational interviewing with MP core components and focus on identifying goals and barriers. Weekly between-group phone/text check-ins are also a part of the curriculum, used to strengthen connection, build trust, ensure safety, and assess basic needs.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mom Power Informational Mailing
Description: This active comparison condition intervention includes two individual sessions along with 10 weeks of informational mailing with content related to Mom Power core concepts.
Study: NCT04568668

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ActionADE
Description: ActionADE is a software application that allows healthcare providers to document standardized adverse drug event information in a user-friendly and standardized manner. We integrated ActionADE uni-directionally with PharmaNet, a secure province-wide network that links all pharmacies in British Columbia to a central data system. This allows care providers to pull in demographic information and visualize their patient's medication dispensing history.~In 2020, we enabled bi-directional integration with PharmaNet allowing clinicians to transmit standardized adverse drug event information back to the PharmaNet database. The three dominant community pharmacy systems in the geographic area of the trial will display the adverse drug event information in their systems, and generate patient-specific medication-level alerts when pharmacists attempt to re-dispense a culprit medication.
Study: NCT04697407

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood sampling
Description: In all groups, 80 ml of blood will be collected. For patients, this will be done during routine cares.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: In all groups, 80 ml of blood will be collected. For patients, this will be done during routine cares.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood sampling
Description: In all groups, 80 ml of blood will be collected. For patients, this will be done during routine cares.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CSF sampling
Description: Only in both patients groups whom will have a CSF sampling in routine care, some CSF will be collected for the study in addition, with a limit of 5 ml for routine care and study.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: CSF sampling
Description: Only in both patients groups whom will have a CSF sampling in routine care, some CSF will be collected for the study in addition, with a limit of 5 ml for routine care and study.
Study: NCT05730465

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Use of Omron Home Blood Pressure Cuff
Description: Use of an Omron Home Blood Pressure Cuff to monitor blood pressure after discharge
Study: NCT05525117

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: covivio (additional to treatment as usual)
Description: Covivio is a dialogue-based online psychological intervention for patients with type 2 diabetes. This intervention includes elements that address disease literacy, physical activity and exercise, dieting and nutritional principles, coping with depression, etc. Content is adapted to users needs using interactive dialogues, illustrations and audio files. Participants may also continue with their usual treatment.

Intervention type: OTHER
Group type: OTHER
Intervention: treatment as usual
Description: Participants may continue with any treatment that they require (treatment as usual)
Study: NCT05449678

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low-carb diet
Description: A close nutritional follow-up will take place with a qualified nutritionist to adapt the participants' usual diet to their assignment diet. This is not a strict diet to follow or a ketogenic diet. Nutritional modifications will be based on the participants' usual diet to improve adherence (personalized follow-up).
Study: NCT05168358

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Overnight Bladder Drainage
Description: Parents or caregivers of the patients will be taught to place an indwelling catheter in the bladder at bedtime for about 8-12 h under a clean technique every night for one year. The catheter will then be allowed to drain freely into a gravity drainage collecting bag or in the diapers. On the next morning, the catheter will be removed and the timed voiding regimen will be resumed.
Study: NCT04104438

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Basiliximab 20 MG
Description: Basiliximab induction followed by tacrolimus, corticosteroids and mycophenolic acid with a switch to everolimus by post operative day 30

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Basiliximab 20 MG
Description: Basiliximab induction followed by tacrolimus, corticosteroids and mycophenolic acid with a switch to everolimus by post operative day 30
Study: NCT05280977

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: POST ISOMETRIC RELAXATION
Description: Group A (Post Isometric Relaxation + Conventional Physiotherapy): This group will receive Muscle Energy Technique in addition to conventional physiotherapy for the treatment of erector spinae tightness. The treatment will be given on alternate days for four weeks with 8 - 10 repetitions of METs per session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: POST FACILITATION STRETCHING
Description: Group B (Post Facilitation Stretching + Conventional Physiotherapy):~This group will receive Post Facilitation Stretching Technique in addition to conventional physiotherapy for the treatment of erector spinae tightness. The treatment will be given on alternate days for four weeks with 8 - 10 repetitions of METs per session.
Study: NCT05813197

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: My Choice - My Way!
Description: Support intervention for adolescents (15+) in out-of-home care (foster care, group home care, supported living, institutional care, etc). 16-19 sessions with a MCMW coach, 4-8 months, weekly to bi-weekly sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual services
Description: Usual services
Study: NCT05120310

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Calm App
Description: Participants will be asked to use the Calm app for at least 10 minutes per day for eight weeks. They will also be asked to schedule one live 20-minute coaching session with a Calm Coach within the first week of the eight-week intervention to help identify areas for health behavior improvements (i.e., Calm Concierge). Participants will be asked to download the Calm app to their mobile phone. The Calm Coaching for sleep program is administered by Calm for six weeks. Participants are asked to complete weekly modules and interact with a coach to help them improve their sleep. Participants also complete a sleep diary throughout the program.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: The Calm App
Description: Participants will be asked to use the Calm app for at least 10 minutes per day for eight weeks. They will also be asked to schedule one live 20-minute coaching session with a Calm Coach within the first week of the eight-week intervention to help identify areas for health behavior improvements (i.e., Calm Concierge). Participants will be asked to download the Calm app to their mobile phone. The Calm Coaching for sleep program is administered by Calm for six weeks. Participants are asked to complete weekly modules and interact with a coach to help them improve their sleep. Participants also complete a sleep diary throughout the program.
Study: NCT04195633

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Given IV
Study: NCT05979571

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile health app
Description: Breastfeeding knowledge and promotion information will be delivered through the AmiBreastfeed app platform
Study: NCT04195633

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Mofetil
Description: Given IV or PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Mofetil
Description: Given IV or PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Sodium
Description: Given PO
Study: NCT04208477

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: one site blockade of the stellate ganglion
Description: Ultrasound guided one site blockade of the stellate ganglion.
Study: NCT05449600

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thermotape
Description: Thermotape will be applied along the left and right forearm. One piece of tape, one inch wide by two inches long, will be applied to each arm. The location the tape, when applied, will be randomized. Altogether, two pieces of this particular tape will be applied, one to each forearm.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tegaderm
Description: Tegaderm™will be applied along the left and right forearm. One piece of tape, one inch wide by two inches long, will be applied to each arm. The location the tape, when applied, will be randomized. Altogether, two pieces of this particular tape will be applied, one to each forearm.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kind
Description: Thermotape will be applied along the left and right forearm. One piece of tape, one inch wide by two inches long, will be applied to each arm. The location the tape, when applied, will be randomized. Altogether, two pieces of this particular tape will be applied, one to each forearm.
Study: NCT05332483

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Megestrol Acetate
Description: Megestrol acetate, 160 mg daily (two 40mg tablets twice a day), for a minimum of 18 days.
Study: NCT04192578

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.
Study: NCT05370859

Intervention type: OTHER
Intervention: There is no intervention for this study
Description: There is no intervention or exposure for this study
Study: NCT04726371

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Generic Best Practices
Description: GBP consists of (1) Massachusetts Executive Office of Health and Human Services distribution of standard guidelines and policies for public health prevention and management of COVID and (2) standard virtual training of the staff of the group homes in these generic COVID-19 prevention practices including recommended use of hand washing, use of PPE, and symptom-triggered screening. Group homes randomized to this intervention will receive standard recommended and fully vetted best practices with respect to preventing and managing COVID-19 based on recommendations by the CDC and on consultation with leading national experts in infectious disease working with the Commonwealth of Massachusetts. The control condition does not represent inferior or substandard practice. As findings occur and as policy leads to adjustments in recommendations during the course of the study, the GBP condition will incorporate recommendations that are appropriate and up-to-date with CDC and state policy.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tailored Best Practices
Description: TBP consists of optimized, tailored, and highly specific COVID-19 best practices and training materials specific to the setting, staff, and residents with SMI and ID/DD in congregate living settings based on the comparative effectiveness of different types, intensities, and combinations of COVID-19 prevention practices (screening, isolation, contact tracing, use of PPP, vaccination) specifically modeled for residents and staff of congregate living settings for people with ID/DD and SMI derived by a simulation model. Results from this modeling process will be provided to stakeholders to support decision makers in prioritizing resources and practices with the greatest impact on reducing COVID-19 tailored for people with SMI and ID/DD in congregate living settings. This process to determine the content of TBP will occur as part of this study prior to randomization.
Study: NCT04195633

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Sodium
Description: Given PO

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Total-Body Irradiation
Description: Undergo total-body irradiation

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Total-Body Irradiation
Description: Undergo total-body irradiation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: Given IV
Study: NCT05648734

Intervention type: DRUG
Intervention: Corticosteroids + Colchicine + Pirfenidone for ≥ 14 days
Description: (≥ 20 mg prednisolone or its equivalent for ≥ 10 days) + Colchicine (1 mg/day for ≥ 10 days) + Pirfenidone (267 mg TID for ≥ 14 days)
Study: NCT05141032

Intervention type: PROCEDURE
Intervention: Endoscopic Submucosal Dissection with Pathfinder/Overtube device
Description: Removal of gastrointestinal polyps via ESD
Study: NCT04195633

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo echocardiography

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo echocardiography

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT or PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT or PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT
Study: NCT05604508

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Many posters with prices
Description: No poster number or price restrictions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Many posters, no prices
Description: No poster number restrictions, but price restrictions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fewer posters, no price restrictions
Description: Poster number restrictions, but no price restrictions
Study: NCT05293470

Intervention type: OTHER
Intervention: Piqray
Description: There is no treatment allocation. Patients administered Piqray by prescription will be enrolled.
Study: NCT05641441

Intervention type: RADIATION
Intervention: Stereotactic radiosurgery
Description: Stereotactic radiosurgery
Study: NCT06521645

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: electrical stimulation is given through needles inserted into the skin

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: sham needle
Description: needles are inserted shallowly into the skin
Study: NCT05931835

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VERAFEYE System
Description: The VERAFEYE System will be used during standard of care, catheter-based treatments for atrial flutter or atrial fibrillation; or left atrial appendage/atrial septal defect closure procedures.
Study: NCT06149286

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Odronextamab
Description: Administered by intravenous (IV) infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Administered orally (PO)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Administered orally (PO)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Administered by IV infusion, or subcutaneously (SC)
Study: NCT05856344

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spherical tip noncompliant balloon
Description: The main difference of this experimental balloon is the spherical tip, other parameters are consistent with regular noncompliant balloons.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Regular noncompliant balloon
Description: The balloon is designed as tapered-tip.
Study: NCT05257486

Intervention type: DEVICE
Intervention: Xoft eBx
Description: The Xoft Axxent Electronic Brachytherapy (eBx) System allows for the administration of high dose rate brachytherapy treatments using an electronic source
Study: NCT05170386

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive training Therapy
Description: Cognitive training Therapy include: Writing the reminiscences~• Solving a table• Writing a letter making a calendar and writing a note about the daily activities on it Facing patients' fears instead of avoiding them.Using role-playing to prepare for potentially problematic interactions with others.Learning to calm one's mind and relax one's body.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: instructive conventional treatment
Description: instructive conventional treatment breathing relaxation exercise inform of diaphragmatic breathing Practice sleep hygiene such as keeping a regular sleep schedule. Get regular exercise. Minimize noise. Minimize light. Manage the temperature so that you're comfortable.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: instructive conventional treatment
Description: instructive conventional treatment breathing relaxation exercise inform of diaphragmatic breathing Practice sleep hygiene such as keeping a regular sleep schedule. Get regular exercise. Minimize noise. Minimize light. Manage the temperature so that you're comfortable.
Study: NCT06184750

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mammography
Description: Undergo mammography

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tamoxifen
Description: Given PO
Study: NCT06514521

Intervention type: OTHER
Intervention: Lutetium vipivotide tetraxetan
Description: This is an observational study. There is no treatment allocation. The decision to initiate Lutetium vipivotide tetraxetan will be based solely on clinical judgement.
Study: NCT04765384

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ad26.COV2.S
Description: Participants will receive intramuscular (IM) injection of Ad26.COV2.S.
Study: NCT05411692

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional electrical stimulations and motor priming exercise
Description: One pair of surface stimulation electrodes is placed on the subject's skin above the flexor digitorum superficialis and the flexor digitorum profundus muscles to generate finger flexion. The Second pair of electrodes is placed on the subject's skin, above the median~nerve, to generate thumb flexion. The third pair of electrodes is placed on the subject's skin, above the extensor digitorum muscle, to generate finger extension. Motor priming exercises will be done (functional task practice, FTP) for 20 minutes. Participants will be asked to spend at least 20 minutesDuration of training will be 4 weeks, 5 days per week, one session per day, and one hour per session.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Functional electrical stimulations
Description: Stimulation parameters are (1) balanced, biphasic, current-regulated electrical pulses; (2) pulse amplitude from 8 to 50 mA (typical values 17- 26 mA); (3) pulse width 250 ms; and (4) pulse frequency from 20 to 70 Hz (18). Trancutaneous stimulation will be delivered bilaterally with surface electrodes placed on the volar aspect of each wrist targeting the distribution of the median nerve. One pair of surface stimulation electrodes is placed on the subject's skin above the flexor digitorum superficialis and the flexor digitorum profundus muscles to generate finger flexion. The Second pair of electrodes is placed on the subject's skin, above the median~nerve, to generate thumb flexion for 20 minutes

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Conventional physical therapy
Description: a structured exercise protocol targeting strength (2 days/week) and endurance (3days/week) training