TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06763237

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS)
Description: The TEAS intervention is delivered using an electroacupuncture device (SDZ-V, Hwato, Soochow Medical Instruments Co., Ltd., China). Self-adhesive electrodes are placed at acupoints Zhongwan (RN12), bilateral Tianshu (ST25), Qihai (RN6), and Guanyuan (RN4). Stimulation is applied using dense-sparse wave alternating frequencies (3 Hz for 2 s cycles) at an intensity of 3-10 mA, adjusted to the participant's tolerance. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.~The ABA therapy focuses on enhancing skills in areas such as social interaction, communication, academics, motor function, and self-care. ABA is delivered in a variety of settings, including school, home, clinic, and other community settings. The goal of treatment is to help children function as independently and successfully as possible. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS)
Description: The TEAS intervention is delivered using an electroacupuncture device (SDZ-V, Hwato, Soochow Medical Instruments Co., Ltd., China). Self-adhesive electrodes are placed at acupoints Zhongwan (RN12), bilateral Tianshu (ST25), Qihai (RN6), and Guanyuan (RN4). Stimulation is applied using dense-sparse wave alternating frequencies (3 Hz for 2 s cycles) at an intensity of 3-10 mA, adjusted to the participant's tolerance. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.~The ABA therapy focuses on enhancing skills in areas such as social interaction, communication, academics, motor function, and self-care. ABA is delivered in a variety of settings, including school, home, clinic, and other community settings. The goal of treatment is to help children function as independently and successfully as possible. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.
Study: NCT06763315

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selumetinib
Description: Use of the internationally recommended standard dose and low dose of the same drug

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Selumetinib
Description: Use of the internationally recommended standard dose and low dose of the same drug
Study: NCT06764667

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spinal anesthesia adjuvant
Description: Patients in this arm will receive 10 mg 0.5% hyperbaric Bupivacaine, 100 mcg Morphine, 100 mcg Sulfas Atropine, and 0.9% normal saline to total volume of 4 ml.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus Lumborum Block (QLB)
Description: Patients in this arm will receive quadratus lumborum block with 20-30 ml of 0.25% Bupivacaine after induction of anesthesia and after operation.
Study: NCT06764355

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: 200 mg, 1h-IVF, Q3W on day 1 for 2 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel 175 mg/m2, 3h-IVF, Q3W on day 1 for 2 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Cisplatin 75 mg/m2, 2h-IVF, Q3W on day 1 for 2 cycles

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Chemoradiotherapy
Description: Chemoradiotherapy~* Paclitaxel 50 mg/m2, 1h-IVF, on days 1, 8,15, 22, and 29;~* Cisplatin 30 mg/m2,1h-IVF, on days 1, 8,15, 22, and 29;~* RT: 1.8 Gy/fraction, 5 days a week, for 25 fractions (total dose= 45 Gy).
Study: NCT06764303

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NTQ5082
Description: NTQ5082 100mg qd

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NTQ5082
Description: NTQ5082 100mg qd
Study: NCT06763003

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music Therapy
Description: The music therapy session described follows a structured and engaging approach, aimed at enhancing the patient's cognitive skills during neurorehabilitation. Here's a summary of the session components: Relaxation Phase, Song Selection, Instrument Selection and Familiarization, Rhythmic Training, Progression and Adjustment, Session Frequency and Customization. This individualized approach aims to enhance patient engagement and recovery by integrating music, rhythm, and therapeutic interaction into the neurorehabilitation process.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care (in control arm)
Description: In the control group, participants will receive the standard neurorehabilitation program prescribed by the rehabilitation team, without the addition of music therapy. This will provide a baseline to compare outcomes with the intervention group and evaluate the feasibility and preliminary effects of the music therapy intervention. The usual cognitive rehabilitation program during the subacute stroke period focuses on restoring cognitive abilities such as attention, memory, executive functions, and communication. The control group's daily rehabilitation sessions will last for 45 minutes, mirroring the music therapy group's session duration, ensuring a fair comparison of outcomes across both groups. This comparison will help assess the unique contributions of music therapy on cognitive functions like attention, memory, and executive functions in stroke patients.
Study: NCT06762821

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single-visit revascularization
Description: Revascularization protocol will be performed in single visit

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Multiple-visit revascularization
Description: Revascularization protocol will be performed in multiple visit
Study: NCT06764394

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: home based exercise 5 days/week

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: home based exercise plus myofacial release exercise Myofascial release exercises will continue for 6 weeks, 2 sessions per week and each session will continue for 30 minutes.All evaluations will be performed at the beginning of radiotherapy treatment and at the end of the 6th week.
Study: NCT06763822

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: close eyes
Description: ask participants to close their eyes for rest

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: close eyes
Description: ask participants to close their eyes for rest

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cold compress
Description: cold compress on participants' eyes for rest

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: cold compress
Description: cold compress on participants' eyes for rest
Study: NCT06764329

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stem Cells
Description: allogeneic bone marrow-derived mesenchymal stem cells therapy

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 0.9 % saline
Description: 0.9% Saline as placebo
Study: NCT05550623

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tourniquet
Description: Tourniquet use in transfemoral amputation.
Study: NCT06098118

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MyMammogram decision aid
Description: An online breast cancer screening decision aid that includes personalized risk assessment, information on benefits and risks of mammography screening, values clarification, outcome expectancies, and a summative document with participant responses.
Study: NCT05467579

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Device: orthodontic - mandibular advancement clear aligner
Description: Intervention orthodontic - mandibular advancement: mandibular retrognathia correction with a mandibular advancement using a step-wise approach with clear aligner.
Study: NCT04758650

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68GaNOTA-Anti-MMR-VHH2
Description: All subjects will receive at least one single intravenous injection of the IMP followed by a total body PET/CT prior to receiving standard-of-care therapy.~For patients in cohorts 1 and 2 : an optional injection of the IMP during or after therapy can be administered if a patient is treated with non-surgical modalities. Patients in cohorts 6 and 7 who receive standard-of-care treatment can receive an optional injection of the IMP.
Study: NCT05055921

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multi Pulse Therapy as delivered from the Cardialen External Stimulation System
Description: The Cardialen External Stimulation System (CESS) is the research delivery system for the proprietary Cardialen MultiPulse Therapy (MPT). The CESS is a custom designed and built research device. It is comprised of off-the-shelf commercial components (power supplies, waveform generators, laptop computer, monitor, rack, ECG system, leads, etc.) combined with a custom electrical circuit board and custom software.~Other Names:~* Unpinning Termination Therapy~* Multi-stage therapy~* Multi-stage electrotherapy~* MultiPulse Therapy
Study: NCT05621642

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Breathing exercises
Description: In the sitting position, the patient does 15 diaphragm breathing and 15 huffing exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing exercises
Description: In the sitting position, the patient does 15 diaphragm breathing and 15 huffing exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Core stabilization exercises
Description: This intervention includes bridging exercise and abdominal exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core stabilization exercises
Description: This intervention includes bridging exercise and abdominal exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Balance and strengthening exercises
Description: It includes sitting and standing on the chair 15 times and turning around the chair.
Study: NCT05467579

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Device: orthodontic - mandibular advancement clear aligner
Description: Intervention orthodontic - mandibular advancement: mandibular retrognathia correction with a mandibular advancement using a step-wise approach with clear aligner.
Study: NCT05975034

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: Probiotic taken daily for 12 weeks.
Study: NCT05621642

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Balance and strengthening exercises
Description: It includes sitting and standing on the chair 15 times and turning around the chair.
Study: NCT06394323

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral: My Choice for HIV Prevention (MyChoice)
Description: My Choice for HIV Prevention (MyChoice), is a counselor-delivered shared decision-making approach for pregnant women considering PrEP
Study: NCT05975034

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo taken daily for 12 weeks.
Study: NCT06502600

Intervention type: PROCEDURE
Intervention: surgery time
Description: This study is a retrospective observational study, with surgery time being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: surgery time
Description: This study is a retrospective observational study, with surgery time being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: surgeon
Description: This study is a retrospective observational study, with surgeon being one of the exposure factors under investigation.
Study: NCT04287816

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Zero hard-boiled egg at 0 h
Description: No eggs will be consumed on test day along with spinach consumption
Study: NCT06502600

Intervention type: PROCEDURE
Intervention: surgeon
Description: This study is a retrospective observational study, with surgeon being one of the exposure factors under investigation.
Study: NCT04287816

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: One hard-boiled egg at 0 h
Description: One egg will be consumed on test day along with spinach consumption

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Two hard-boiled eggs at 0 h
Description: Two eggs will be consumed on test day along with spinach consumption

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three hard-boiled eggs at 0 h
Description: Three eggs will be consumed on test day along with spinach consumption

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: One hard-boiled egg at 3 h
Description: One egg will be consumed on test day three hours after spinach consumption

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: One hard-boiled egg at 0 h + One hard-boiled egg at 3 h
Description: Two eggs will be consumed on test day: one along with spinach consumption and the other one three hours after spinach consumption
Study: NCT06502600

Intervention type: PROCEDURE
Intervention: surgical procedure duration
Description: This study is a retrospective observational study, with surgical procedure duration being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: surgical procedure duration
Description: This study is a retrospective observational study, with surgical procedure duration being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: operating room
Description: This study is a retrospective observational study, with surgical procedure duration being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: operating room
Description: This study is a retrospective observational study, with surgical procedure duration being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: type of surgery
Description: This study is a retrospective observational study, with type of surgery being one of the exposure factors under investigation.

Intervention type: PROCEDURE
Intervention: type of surgery
Description: This study is a retrospective observational study, with type of surgery being one of the exposure factors under investigation.
Study: NCT04614610

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine Iv
Description: Lidocaine 1.5mg/kg (Max dose: 200mg) in Dextrose 5% 100mL over 10 minutes

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Dextrose 5% 100mL over 10 minutes
Study: NCT06403163

Intervention type: PROCEDURE
Intervention: Transfusion
Description: Transfusion of an hemostatic product
Study: NCT05256654

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3561774
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3561774
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3561774
Description: Administered SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study: NCT06394323

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral: My Choice for HIV Prevention (MyChoice)
Description: My Choice for HIV Prevention (MyChoice), is a counselor-delivered shared decision-making approach for pregnant women considering PrEP
Study: NCT06053099

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plasma ctDNA
Description: * Plasma ctDNA before surgery (optional)~* Plasma ctDNA post-surgery : 4 to 8 weeks post-surgery, before starting adjuvant chemotherapy (if given) and before starting adjuvant osimertinib (if given)~* Plasma ctDNA every 6 months~* Plasma ctDNA at relapse

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FFPE blocks
Description: * Surgery FFPE blocks~* FFPE blocks at relapse (optional)
Study: NCT05737056

Intervention type: OTHER
Intervention: Management of rheumatoid purpura
Description: Collection of data on the management in pediatric emergency departments (method of diagnosis, complementary examinations, proposed treatment, number of hospitalizations, follow-up after hospital discharge).
Study: NCT06176365

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Survodutide
Description: once weekly subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Survodutide
Description: once weekly subcutaneous injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo matching survodutide
Description: once weekly subcutaneous injection
Study: NCT05538962

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sensor skin
Description: Skin sensor to detect inflammatory molecules in sweat

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sensor skin
Description: Skin sensor to detect inflammatory molecules in sweat

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sensor skin
Description: Skin sensor to detect inflammatory molecules in sweat
Study: NCT05739669

Intervention type: DEVICE
Group type: OTHER
Intervention: EEG recording with the comparator device Micromed Brain Quick
Description: Each patient will undergo a visit in a clinic, during which a 15 minutes long EEG trace with a CE-certified wet electrode EEG Device (Micromed Brain Quick) will be recorded by specialized staff.

Intervention type: DEVICE
Group type: OTHER
Intervention: EEG recording with the investigational device Atlas with dry electrodes clinic/specialized staff
Description: During the same visit when the wet electrode EEG is recorded, the patient will be subjected to a second 15 minutes long EEG recording with the investigational device Atlas with dry electrodes, which will be conducted by specialized staff

Intervention type: DEVICE
Group type: OTHER
Intervention: EEG recording with the investigational device Atlas with dry electrodes home/lay people
Description: The patients will record their own EEGs at home daily for 14 days, using the investigational device Atlas with dry electrodes
Study: NCT05144932

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Stroke Alarm
Description: The patients are in this clinical trial instructed to use the device continuously for 1 month.
Study: NCT05242497

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: pharmacopuncture
Description: This is a pragmatic randomized controlled trials, so the physicians will choose pharmacopuncture treatment, including the type and doses, according to each participant's conditions. The researcher will record the specific intervention precisely and concurrently.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conservative treatments (including physiotherapy)
Description: This is a pragmatic randomized controlled trials, so the physicians will choose conservative treatment, including physiotherapy and pharmacological treatment, according to each participant's conditions. The researcher will record the specific intervention precisely and concurrently.
Study: NCT04774523

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echo-based assessment of the acute hemodynamic effect of the CRT AutoAdapt feature.
Description: Patients in the AutoAdapt group undergo the echo-based assessment of the acute hemodynamic effect of the CRT AutoAdapt feature.~Three steps must be followed:~1. Standard AV programming: perform echo for AoVTI assessment.~2. Echo-optimized AV programming: perform standard echo-based AV-optimization (Ritter method or iterative method, according to routine at investigational site); measure AoVTI at optimized setting.~3. AutoAdapt optimized programming: The system allows different programming options for the parameter 'Adaptive AV reduction'. The nominal value is 0.7, but it can be modified to different values ranging from 0.5 to 0.9. The AoVTI shall be measured at standard setting of the Adaptive Av reduction parameter, 0.7.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Echocardiography AV optimization
Description: Patient in the control group undergo the routine echo-based AV-optimization that is usually performed at the investigational site (Ritter method or iterative method). Performance of an additional VV-delay optimization is left to the investigator discretion

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Echocardiography must be performed at baseline and 12 month Follow Up to collect the LVEF/LVESD(V)/LVEDD(V)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Echocardiography
Description: Echocardiography must be performed at baseline and 12 month Follow Up to collect the LVEF/LVESD(V)/LVEDD(V)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self Assessment Score
Description: Patient must complete the self assessment score at 6 and 12 month Follow Up, that will be use for the Packer Clinical Composite Score

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self Assessment Score
Description: Patient must complete the self assessment score at 6 and 12 month Follow Up, that will be use for the Packer Clinical Composite Score
Study: NCT05185778

Intervention type: BIOLOGICAL
Intervention: stool examination, blood sample collected
Description: Stool examination macroscopically for consistency, color, and presence of blood and/or mucus and microscopically using the following methods:~* Saline and iodine wet mount.~* Formalin-ethyl acetate sedimentation method.~* Modified Ziehl-Nielsen staining : It was done to all cases with manifestations suggestive of protozoa.~  * Collection of peripheral blood samples for Automated CBC and blood indices evaluation.~ * Molecular detection of inflammatory cytokines level (IFNγ, TNFα) and antiinflammatory cytokines (IL4, IL10) by Real-time PCR(polymerase chain reaction).

Intervention type: BIOLOGICAL
Intervention: stool examination, blood sample collected
Description: Stool examination macroscopically for consistency, color, and presence of blood and/or mucus and microscopically using the following methods:~* Saline and iodine wet mount.~* Formalin-ethyl acetate sedimentation method.~* Modified Ziehl-Nielsen staining : It was done to all cases with manifestations suggestive of protozoa.~  * Collection of peripheral blood samples for Automated CBC and blood indices evaluation.~ * Molecular detection of inflammatory cytokines level (IFNγ, TNFα) and antiinflammatory cytokines (IL4, IL10) by Real-time PCR(polymerase chain reaction).
Study: NCT06311500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep health enhancement intervention
Description: 4 weekly visits of education and strategies to enhance sleep health
Study: NCT06144710

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SG301 SC Injection
Description: Subcutaneous injection every two weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SG301 SC Injection
Description: Subcutaneous injection every two weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SG301 SC Placebo
Description: Subcutaneous injection every two weeks