TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06621771

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music intervention
Description: Participants will engage in a step-by-step piano training consisting in playing piano pieces designed to involve all 5 digits of the paretic hand and increasing in complexity. They will be using a Musical Instrument Digital Interface (MIDI) piano program called Synthesia to display musical pieces on a computer screen that is adapted for people with no music reading abilities and will be playing on a touch sensitive piano keyboard. The supervised session will also be complemented with a unsupervised home program consisting of piano sequence exercises comprising short excerpts of the same musical pieces practiced during the supervised sessions and they will receive a roll-up flexible piano

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Occupational Therapy
Description: Participants will receive conventional occupational therapy treatment (e.g., mobility, ADL, IALD, information session), excluding treatments focusing specifically on arm and hand motor recovery.The supervised session will also be complemented with an unsupervised home program consisting of assignments related to occupational therapy exercises and/or IALD/ADLs.
Study: NCT06696690

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MNS
Description: The MNS treatment group use the NeuroTrac™ Multi-TENS transcutaneous electrical stimulator to provide an asymmetric biphasic pulse train with a frequency of 35 Hz, an amplitude of 20 mA and a pulse width of 300 ms, which is on for 20 seconds and off for 50 seconds. The treatment lasts for 8 hours per day and the treatment course lasts for one week.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham stimulation
Description: The sham stimulation treatment group utilized the same stimulation device and was subjected to a safe yet ineffective stimulation protocol for sham stimulation. The treatment lasts for 8 hours per day and the treatment course lasts for 14 days.
Study: NCT06699693

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ultrasonography-guided PENG block
Description: This study aimed to evaluate the effect of ultrasonography-guided PENG block prior to joint mobilization therapy on shoulder pain, function, and kinesiophobia in patients with AC resistant to conservative treatment, in comparison with a control group

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mobilization
Description: The mobilization methods encompassed the scapula and clavicular joints, in addition to the glenohumeral (GH) joint, taking into consideration their biomechanical interactions. These exercises were supervised and administered by the physiotherapist during each session. Additionally, the patients were provided with a home exercise program that included exercises for posture, thera band, and finger ladder, with instructions to perform 10-15 repetitions twice a day independently \[
Study: NCT06698783

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fortimel
Description: In this study, patients will be provided with ONS preparation (4 kinds of ready-to-drink special medical food) free of charge during the treatment period. Doctors will provide patients with different flavor nutritional preparations on a weekly basis, 2 bottles per day for patients with 1 flavor per week, and 14 bottles per day for each of 4 flavors at the recommended dosage of 400 kcal per day 28 days
Study: NCT06699784

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Progressive lenses intervention
Description: Progressive lenses intervention group will receive 1-month progressive lens correction in daily life.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Single-vision lenses intervention
Description: Single-vision lenses intervention group will use near-vision spectacles during near work and use their original habitual distant glasses for distance tasks for 1 month.
Study: NCT06699316

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Individualized prognostic counselling
Description: Individualized prognostic counselling on life expectancy using the prognostic model 'OncologIQ Palliative'
Study: NCT06699576

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-20093
Description: HS-20093: administered as an IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-20093
Description: HS-20093: administered as an IV infusion
Study: NCT05850806

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The KmAsthma self-management smart phone app intervention
Description: KmAsthma is a free app which enables users to track their symptoms, access their action plan, learn about asthma and set goals to make change
Study: NCT04945278

Intervention type: OTHER
Group type: OTHER
Intervention: Double mirror device ALTER-EGO
Description: The patient and his matched healthy volunteer will be placed on each side of the double mirror device ALTER-EGO. Both sides will be lightened alternatively or at the same time by lights, so according to the light intensity, the subject will see himself in a mirror or the other person throw a classic window. The light intensity will vary from 0 to 100% and to 100% to 0% alternatively from each side of the mirror. At each 10% variation of one side, both patient and volunteer will have to answer that question : who do you see more : him/her or yourself ?

Intervention type: OTHER
Group type: OTHER
Intervention: Double mirror device ALTER-EGO
Description: The patient and his matched healthy volunteer will be placed on each side of the double mirror device ALTER-EGO. Both sides will be lightened alternatively or at the same time by lights, so according to the light intensity, the subject will see himself in a mirror or the other person throw a classic window. The light intensity will vary from 0 to 100% and to 100% to 0% alternatively from each side of the mirror. At each 10% variation of one side, both patient and volunteer will have to answer that question : who do you see more : him/her or yourself ?

Intervention type: OTHER
Group type: OTHER
Intervention: EASE test
Description: The patient will have to answer the EASE test which is a specific test to detect patient with high risk of psychosis or schizophrenia
Study: NCT05131867

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nimodipine
Description: (60 mg/4 hours) orally or via nasogastric tube

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral Nimodipine and milrinone
Description: Oral Nimodipine then after the diagnosis of vasospasm is confirmed, start milrinone bolus
Study: NCT06014606

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: oral formulation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: haloperidol 2mg
Description: oral formulation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: propranolol 40mg
Description: oral formulation
Study: NCT06801002

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JBZ-001
Description: JBZ-001 Oral Capsule
Study: NCT06800521

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mixed Reality Breastfeeding Education
Description: Mixed Reality Breastfeeding Education:~This intervention includes an innovative mixed reality-based educational strategy combined with traditional breastfeeding counseling. Participants use mixed reality goggles to experience immersive breastfeeding scenarios, interact with audio-visual materials tailored for breastfeeding education, and engage with realistic breastfeeding simulations. The session is delivered once during the third trimester of pregnancy and lasts approximately 90 minutes. This intervention is designed to improve maternal confidence, satisfaction, and adherence to exclusive breastfeeding through an engaging and practical learning environment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Breastfeeding Counseling
Description: This intervention involves standard prenatal breastfeeding education provided by trained healthcare professionals. Participants receive verbal and visual explanations of breastfeeding techniques, benefits, and solutions to common challenges. Delivered in a single session during the third trimester of pregnancy, the session lasts approximately 60 minutes and represents the current standard of care in breastfeeding education.
Study: NCT06801990

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: S1 transforaminal epidural steroid(dexamethasone) injection
Description: The designed study will examine the effect of oblique entry angles on contrast distribution patterns and treatment outcomes. Therefore, it aims to compare the smallest and largest angles that can be achieved under co-axial imaging at the S1 foramen. For this purpose, patients will be divided into two groups through randomization using a computer program. In the first group, after angling cranially and visualizing the foramen, the needle entry point will be determined. In the second group, after achieving optimal imaging by cranially angling the C-arm fluoroscope, an additional ipsilateral oblique angle will be applied to the fluoroscope.~In this context, Plastaras et al. reported that an angle of 5° ± 5° is the most suitable range for the S1 foramen. Additionally, another study examining dorsal and ventral S1 foramen via tomography images found that the average angle providing the widest view of the dorsal foramen was 26.6° ± 3°. In the current study, no oblique angle will be applied

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: S1 transforaminal epidural steroid(dexamethasone) injection
Description: The designed study will examine the effect of oblique entry angles on contrast distribution patterns and treatment outcomes. Therefore, it aims to compare the smallest and largest angles that can be achieved under co-axial imaging at the S1 foramen. For this purpose, patients will be divided into two groups through randomization using a computer program. In the first group, after angling cranially and visualizing the foramen, the needle entry point will be determined. In the second group, after achieving optimal imaging by cranially angling the C-arm fluoroscope, an additional ipsilateral oblique angle will be applied to the fluoroscope.~In this context, Plastaras et al. reported that an angle of 5° ± 5° is the most suitable range for the S1 foramen. Additionally, another study examining dorsal and ventral S1 foramen via tomography images found that the average angle providing the widest view of the dorsal foramen was 26.6° ± 3°. In the current study, no oblique angle will be applied
Study: NCT06801184

Intervention type: BIOLOGICAL
Intervention: Plasma Sample
Description: A peripheral venous blood sample will be collected on the day of the inclusion consultation and during the follow-up consultation at V2. These samples will be collected in a single2 tubes (4 mL and 5 mL)l tube and will be taken simultaneously with routine blood samples, which require 2 tubes (10 3 mL and 4 mLl).

Intervention type: BIOLOGICAL
Intervention: Stool Sample
Description: Approximately 1 gram of stool will be collected by the patient at home within 72 hours following the inclusion consultation and the follow-up consultation at V2, using the kits provided along with the instructions. The stools will be immediately collected into two tubes: one tube with nucleic acid preservative and one tube conservative to ensure for future metabolomic analyses. The patient will then send the sample using the pre-paid envelope included in the kit to the HCL microbiota biobank (CRB GHN) for aliquoting and storage at -80°C.
Study: NCT06801808

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Myosave
Description: Nutritional supplementation with Myosave

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Myosave
Description: Nutritional supplementation with Myosave
Study: NCT06801236

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACE-232 tablets
Description: ACE-232 tablets will be administered orally daily as a continuous regimen together with Dexamethasone and Fludrocortisone. Subjects will continue to receive study treatment until PD as judged by local investigator review, development of unacceptable toxicity, or withdrawal of consent.
Study: NCT06801470

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD-001
Description: CD-001 administered as an intravenous (IV) infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD-001
Description: CD-001 administered as an intravenous (IV) infusion.
Study: NCT06801275

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1 shower with 4% chlorhexidine gluconate
Description: Comparison of the effect of showering once with 4% Chlorhexidine Gluconate before lumbar disc herniation surgery on surgical site infections

Intervention type: OTHER
Group type: OTHER
Intervention: 2 shower with 4% chlorhexidine gluconate
Description: Comparison of the effect of showering twice with 4% Chlorhexidine Gluconate before lumbar disc herniation surgery on surgical site infections
Study: NCT06800742

Intervention type: OTHER
Intervention: Collection of anthropometric and biochemical parameters
Description: Collection of anthropometric parameters biochemical parameters basal metabolic rate body composition questionnaires

Intervention type: OTHER
Intervention: Collection of anthropometric and biochemical parameters
Description: Collection of anthropometric parameters biochemical parameters basal metabolic rate body composition questionnaires
Study: NCT06801899

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Total pancreatectomy (TP)
Description: The investigators perform TP in patients who undergo surgical resection of a malignant tumor in the pancreatic head.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Partial pancreaticoduodenectomy (PD)
Description: The investigators perform partial PD with anastomosis of the pancreas in patients who undergo surgical resection of a malignant tumor in the pancreatic head. This is the current standard procedure.
Study: NCT06802042

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention with probiotic bacteria
Description: The intervention group (n=20) received free intervention with probiotic bacteria (Lactobacillus reuteri DSM 8 +) for 4 weeks (1 bag bid)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactulose oral solution treatment
Description: The control group (n=20) received lactulose oral solution free of charge for 4 weeks (1-2 bags qd for the first three days, and then increased or reduced according to constipation)
Study: NCT06801249

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metarapone
Description: Metirapone is an inhibitor of the enzyme 11-β-adrenal hydroxylase, which is deputed to catalyze the conversion of 11-desoxycortisol (11-S) to cortisol and 11-deoxycorticosterone (DOC) to corticosterone.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standardized antihypertensive therapy
Description: Standardized antihypertensive therapy, as provided in the normal course of care and in accordance with current European guidelines.
Study: NCT06800833

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low fat cookies
Description: To determine the effects of low fat cookie consumption on physiological indicators of sexual, mental, skin, and gut health

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mango
Description: To determine the effects of mango consumption on physiological indicators of sexual, mental, skin, and gut health
Study: NCT06801587

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone acetonide plus ropivacaine
Description: The local infiltration solution in the triamcinolone acetonide plus ropivacaine group will consist of ropivacaine and triamcinolone acetonide. For local infiltration, a total of 30mL solution will be prepared for each group, 1 ml of triamcinolone acetonide (40mg per 1ml) plus 15 ml of 1% ropivacaine diluted to 30 ml with saline as the test drug in the triamcinolone acetonide group. The surgeon will perform incision infiltration before the skin incision. A total of 10 mL of solution will be injected into each level. The study solution will be injected into the entire thickness of the planned incision site. The epidural space and intrathecal space will not be infiltrated.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine alone
Description: The local infiltration solution in the ropivacaine alone group will consist of ropivacaine alone. For local infiltration, a total of 30mL solution will be prepared for each group, which will include 15ml of ropivacaine added to 15mL of saline for ropivacaine group . The surgeon will perform incision infiltration before the skin incision. A total of 10 mL of solution will be injected into each level. The study solution will be injected into the entire thickness of the planned incision site. The epidural space and intrathecal space will not be infiltrated.
Study: NCT06800352

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.
Study: NCT06801600

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Weight-based dosing
Description: Hyperbaric bupivacaine 0.5% dosage will be calculated and administered intrathecally as 0.4 mg/kg or 0.08 ml/kg if body weight ≤ 15 kg and 0.3 mg/kg or 0.06 ml/kg if body weight \> 15 kg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Age-based dosing
Description: Hyperbaric bupivacaine 0.5% will be administered at the dose of age divided by 5 (in ml). The age in months after the completion of a year was noted and considered as the next age if it is more than 6 months and the same age if it is ≤ 6 months.
Study: NCT06800859

Intervention type: DRUG
Intervention: Supplement fluids
Description: To ensure optimal recovery and manage potential complications, patients are advised to supplement fluids by increasing their oral intake or receiving intravenous fluids as necessary. Bed rest is recommended to reduce physical strain and promote healing. Additionally, a blood patch procedure may be performed to alleviate symptoms such as headaches that can occur after certain medical procedures, particularly spinal taps. This involves injecting a small amount of the patient's own blood into the epidural space to seal any leaks of cerebrospinal fluid, thereby providing relief and aiding in recovery. Proper monitoring and follow-up care are essential to ensure the effectiveness of these interventions

Intervention type: DRUG
Intervention: Supplement fluids
Description: To ensure optimal recovery and manage potential complications, patients are advised to supplement fluids by increasing their oral intake or receiving intravenous fluids as necessary. Bed rest is recommended to reduce physical strain and promote healing. Additionally, a blood patch procedure may be performed to alleviate symptoms such as headaches that can occur after certain medical procedures, particularly spinal taps. This involves injecting a small amount of the patient's own blood into the epidural space to seal any leaks of cerebrospinal fluid, thereby providing relief and aiding in recovery. Proper monitoring and follow-up care are essential to ensure the effectiveness of these interventions
Study: NCT06801132

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online self-delivered death anxiety intervention
Description: The online self-guided death anxiety intervention developed in this study is based on the Death Education and CBT framework. It took approximately two hours to complete the full intervention. The main content includes:~1. Emotional reactions and behavioral manifestations about death, fear management theories, and Chinese cultural attitudes toward death;~2. Imagine what you would like to say to yourself at the end of your life, and learn about various attitudes towards death through numerous examples;~3. Expressive writing, with moderate emotional exposure to stimulate reflection, accompanied by breathing exercises and positive thinking about death, to improve tolerance and control of death anxiety, and finally to correct biased perceptions by examining bad beliefs about death;~4. Prioritize the importance of things and make a practical action plan to enrich your life.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Waiting-List (WL) condition
Description: Participants assigned to WL will be asked not to use our death anxiety intervention or seek additional help related to death anxiety during the 1-week intervention period. After the one-month follow-up of the experimental group, the WL group will receive the same intervention for death anxiety. WL participants will also be given contact information to use in case of increasing distress.
Study: NCT06801652

Intervention type: OTHER
Intervention: Sperm morphology indexes
Description: We analyzed all sperm morphology indexes in all groups.

Intervention type: OTHER
Intervention: Sperm morphology indexes
Description: We analyzed all sperm morphology indexes in all groups.

Intervention type: OTHER
Intervention: Sperm morphology indexes
Description: We analyzed all sperm morphology indexes in all groups.

Intervention type: OTHER
Intervention: Sperm morphology indexes
Description: We analyzed all sperm morphology indexes in all groups.
Study: NCT06801015

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Both interventions are approved by FDA for the treatment of obesity and are administered by subcutaneous injection once per week

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Semaglutide
Description: Both interventions are approved by FDA for the treatment of obesity and are administered by subcutaneous injection once per week

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Both interventions are approved by FDA for the treatment of obesity and are administered by subcutaneous injection once per week