TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03653728

Intervention type: DEVICE
Intervention: Near infrared spectroscopy
Description: All patients would be receiving the same treatment including application of non-invasive monitoring with near-infrared spectroscopy (NIRS) together with the standard of care with interval CT Brain scan for all patients.~Non-invasive monitoring with near-infrared spectroscopy (NIRS) is very safe and is in current daily routine clinical use for intraoperative patients.
Study: NCT05510336

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Arthrocentesis
Description: Injection of lactated ringer solution in the TMJ to wash out inflammatory mediators and help reducing anterior disc displacement with reduction

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Arthrocentesis
Description: Injection of lactated ringer solution in the TMJ to wash out inflammatory mediators and help reducing anterior disc displacement with reduction
Study: NCT04955327

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: A. Paniculata
Description: Extract from A. Paniculata

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: A. Chilensis
Description: Extract from A. Chilensis
Study: NCT06529471

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage group
Description: The patient in the massage group will be visited by the practitioner 3 times at 10:00-14:00-20:00 on the first day after surgery and a back massage will be applied. The patient in the massage group will be placed in an orthopnea position during the application. The massage procedure lasts an average of 30 minutes and is applied to the cervical 3 and thoracic 12 vertebrae.
Study: NCT06239077

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non Invasive Prenatal Test via blood sample
Description: Maternal - blood draw, Paternal - blood draw/Saliva sample
Study: NCT03527537

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin
Description: Insulin may be administered base on glucose log values. The dosing of the insulin will be determined by the provider using typical management of gestational diabetes.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin
Description: Insulin may be administered base on glucose log values. The dosing of the insulin will be determined by the provider using typical management of gestational diabetes.
Study: NCT05244122

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback
Description: presence or absence of trial by trial feedback

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prevalence
Description: In some blocks, skin cancer target images were present on 50% of trials (high prevalence). In other blocks, disease prevalence was 20%.
Study: NCT04812301

Intervention type: RADIATION
Intervention: Egg-white sandwich
Description: 1 mCi of Tc-99m sodium phytate is added into the egg-white sandwich

Intervention type: RADIATION
Intervention: Egg-white sandwich
Description: 1 mCi of Tc-99m sodium phytate is added into the egg-white sandwich

Intervention type: RADIATION
Intervention: Abbott Vital®
Description: 1 mCi of Tc-99m sodium phytate is added into the Abbott Vital®

Intervention type: RADIATION
Intervention: Abbott Vital®
Description: 1 mCi of Tc-99m sodium phytate is added into the Abbott Vital®
Study: NCT05463315

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Moziak Device
Description: Applying Moziak Device Compared to Standard Manual Compression
Study: NCT05507840

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Valeda machine
Description: Photobiomodulation treatment with Valeda machine will be applied every six months for 2 years in patients with dry age related macula degeneration.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Valeda machine
Description: Photobiomodulation treatment with Valeda machine will be applied every six months for 2 years in patients with dry age related macula degeneration.
Study: NCT05946564

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pioglitazone (ACTOS®)
Description: Patient will be randomize in the intervention group receive treatment by pioglitazone (30 mg/day orally) for 26 weeks on top of a SOC immunosuppressive treatment.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of Pioglitazone
Description: Patient will be randomize in the intervention group receive treatment by placebo of pioglitazone (30 mg/day orally) for 26 weeks on top of a SOC immunosuppressive treatment.
Study: NCT05431816

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Dietary intervention
Description: dietary fiber （Inulin 4g，Resistant Starch 4g，β-glucan 2g）

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: dietary fiber （Inulin 4g，Resistant Starch 4g，β-glucan 2g）
Study: NCT05682638

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: LVRNA009
Description: 100μg/1.0ml/dose(50 μg/0.5ml/Vial), 2 injection with 28 days apart

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LVRNA009
Description: 100μg/1.0ml/dose(50 μg/0.5ml/Vial), 2 injection with 28 days apart

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 0.9%NaCl
Description: 1.0ml/dose, 2 injection with 28 days apart

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 0.9%NaCl
Description: 1.0ml/dose, 2 injection with 28 days apart
Study: NCT06146010

Intervention type: OTHER
Intervention: No intervention
Description: Once the patient or their legal guardian has given their written consent, a patient is included in the leptomeningeal disease register. Due to the rapid course of the disease and potential rapid deterioration, the documentation of the course of the disease of the individual patients is to be carried out retrospectively from the data recorded during the course of the clinical routine for the entire duration of the study or until the death of the participating patients after the written consent of the patients. The registry's data sources are the diagnostic findings made at the center and doctors' letters from routine clinical practice. The participating centers carry out the assessment of the participants' performance status so that the patients do not have to complete any study-related questionnaires.
Study: NCT04819243

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pabociclib, Endocrine(or ET + CDK4/6 inhibitors), Talazoparib, Atezolizumab
Description: * Palbociclib 125mg~* AI~* GnRH agonist (or ET + CDK4/6 inhibitors + GnRH agonist)~* Talazoparib~* Atezolizumab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pabociclib, Endocrine(or ET + CDK4/6 inhibitors), Talazoparib,
Description: * Palbociclib 125mg~* AI~* GnRH agonist (or ET + CDK4/6 inhibitors + GnRH agonist)~* Talazoparib
Study: NCT06026163

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caffeine citrate
Description: Caffeine citrate in loading dose 20 mg/kg (equivalent for 10 mg/kg caffeine base) and maintenance dose 10 mg/kg/day (equivalent for 5 mg/kg caffeine base)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Equivalent volume of saline
Study: NCT05057494

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Dose formulation: Capsule or Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Dose formulation: Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Dose formulation: Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Dose formulation: Injection
Study: NCT04955327

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: A. Paniculata and A. Chilensis
Description: Combination of A. Paniculata and A. Chilensis

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Microcrystalline cellulose
Description: Placebo comparator
Study: NCT05167669

Intervention type: DEVICE
Group type: OTHER
Intervention: HIFU-MRI guided
Description: HIFU application under MRI guiding to deliver hypothermia to eligible bone metastases before clinical indicated radiotherapy
Study: NCT05778617

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ambroxol Hydrochloride (420mg)
Description: Oral tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral tablet
Study: NCT06145100

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound including color doppler ultrasound
Description: Patients with CVID receive color doppler ultrasound of the liver including assessment of portal vein diameter, portal vein flow velocity, hepatic vein diameter and assessment of arterial perfusion. Further liver and spleen stiffness measurement by transient elastography is performed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound including color doppler ultrasound
Description: Patients with CVID receive color doppler ultrasound of the liver including assessment of portal vein diameter, portal vein flow velocity, hepatic vein diameter and assessment of arterial perfusion. Further liver and spleen stiffness measurement by transient elastography is performed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound including color doppler ultrasound
Description: Patients with CVID receive color doppler ultrasound of the liver including assessment of portal vein diameter, portal vein flow velocity, hepatic vein diameter and assessment of arterial perfusion. Further liver and spleen stiffness measurement by transient elastography is performed.
Study: NCT05896800

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nitric Oxide Generation and Delivery System
Description: The Nitric Oxide Generation and Delivery System is used to deliver nitric oxide for inhalation therapy into the inspiratory limb of the patient breathing circuit in a way that provides a constant concentration of nitric oxide (NO), as set by the user, to the patient throughout the inspired breath.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nitric Oxide Generation and Delivery System
Description: The Nitric Oxide Generation and Delivery System is used to deliver nitric oxide for inhalation therapy into the inspiratory limb of the patient breathing circuit in a way that provides a constant concentration of nitric oxide (NO), as set by the user, to the patient throughout the inspired breath.
Study: NCT06460805

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Partial enteral nutrition
Description: 70% caloric intake from enteral nutrition formula and 30% caloric intake from a limited range of solid foods

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Partial enteral nutrition
Description: 70% caloric intake from enteral nutrition formula and 30% caloric intake from a limited range of solid foods
Study: NCT04814173

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: One-jaw mechanic total maxillary arch distalization
Description: A group of patients in which participants will be undergo to the one-jaw mechanic for mini-implants anchored total-maxillary-arch-distalization (the mini-implants will be inserted in the maxillary arch between the roots of 2nd premolar and 1st molar and closer to the molar, then a force of 250 g will be applied from the TAD to a hook lateral to the laterals).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Two-jaw mechanic total maxillary arch distalization
Description: A group of patients in which participants will be undergo to the tow-jaw mechanic for mini-implants anchored total-maxillary-arch-distalization (the mini-implants will be inserted in the mandibular arch between the 2nd premolar and 1st molar, then, a class II elastics 3/16 and 6.5oz will be use from the TAD to the hook of canines brackets).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: en-mass retraction
Description: A group of patients in which participants will be undergo to the en-mass retraction with first premolars extraction with mini-implants in the maxillary arch inserted between the 2nd premolar and 1st molar, then a force of 250 g will be applied from the TAD to a hook lateral to the laterals .
Study: NCT04915365

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetazolamide
Description: Acetazolamide (oral capsules @125 mg), starting dose 3 capsules (375 mg), subsequent doses 1 capsule (125 mg) in the morning, 2 capsules (250 mg) in the evening, administered in qualifying participants, during the stay at 3100 m.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (oral capsules, identically looking as active drug), starting dose 3 capsules, subsequent doses~1 capsule in the morning, 2 capsules in the evening, administered in qualifying participants, during the stay at 3100 m.
Study: NCT05967793

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: kinesio tape
Description: Kinesio Tape will be applied on paraspinal trunk extensors muscles for 8 weeks, changed every 3 days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesio tape
Description: Kinesio Tape will be applied on paraspinal trunk extensors muscles for 8 weeks, changed every 3 days.
Study: NCT05693428

Intervention type: DRUG
Group type: OTHER
Intervention: Propofol
Description: To maintain anaesthesia in Group 1 P, propofol was used as an anaesthetic in a dose of 5-6 mg/kg/h intravenously on a perfusor.

Intervention type: DRUG
Group type: OTHER
Intervention: Isoflurane
Description: isoflurane was used as anaesthetice of - 1.1-1.2 MAC.

Intervention type: DRUG
Group type: OTHER
Intervention: Sevoflurane
Description: sevoflurane was used as an anaesthetic in a dose of - 1.7-1.9 MAC
Study: NCT06296784

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: e-health psychoeducation
Description: e-health psychoeducation intervention provides information about BD clinical condition and symptoms, as well as identifying effective coping strategies to manage symptoms and the dysregulation of biological rhythms. The content covered the impact of the pandemic and its related restrictions on mental health, particularly on anxiety and depressive symptoms. The intervention comprised one session per week for two months, and each session lasted approximately an hour and a half. It was conducted by healthcare professionals.
Study: NCT06012214

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ROBOTIC-ASSISTED ESOPHAGECTOMY
Description: Comparison between robotic and conventional minimally invasive esophagectomy

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: ROBOTIC-ASSISTED ESOPHAGECTOMY
Description: Comparison between robotic and conventional minimally invasive esophagectomy
Study: NCT00614640

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DermaVir patch
Description: DNA Vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DermaVir patch
Description: DNA Vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DermaVir patch
Description: DNA Vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo patch
Description: 10% dextrose (D-glucose) solution
Study: NCT04665986

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Navelbine
Description: Navelbine 25mg/m2 on day 1 and 8, every 3 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Docetaxel
Description: Docetaxel 90mg/m2 on day 1, every 3 weeks
Study: NCT06602739

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGN5713
Description: Administered per protocol
Study: NCT05513833

Intervention type: OTHER
Group type: OTHER
Intervention: Standard School Screening and Referral
Description: Counties in the control condition will use standard hearing screening and standard referral by school district. Standard referral is typically a letter home from the school to parents/caregivers of children who refer screening.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard School Screening and Referral
Description: Counties in the control condition will use standard hearing screening and standard referral by school district. Standard referral is typically a letter home from the school to parents/caregivers of children who refer screening.

Intervention type: OTHER
Group type: OTHER
Intervention: Enhanced mHealth Screening
Description: The enhanced screening protocol will consist of an mHealth-based hearing screen combined with tympanometry.

Intervention type: OTHER
Group type: OTHER
Intervention: Enhanced mHealth Screening
Description: The enhanced screening protocol will consist of an mHealth-based hearing screen combined with tympanometry.

Intervention type: OTHER
Group type: OTHER
Intervention: Specialty Telemedicine Referral
Description: The specialty telemedicine referral will include a lay-friendly smartphone or tablet that connects to tools necessary for an ear and hearing evaluation. If a child requires referral from hearing screening, a school nurse/teacher will complete the established protocol for the specialty telemedicine referral and send details asynchronously to an audiologist for consultation.

Intervention type: OTHER
Group type: OTHER
Intervention: Specialty Telemedicine Referral
Description: The specialty telemedicine referral will include a lay-friendly smartphone or tablet that connects to tools necessary for an ear and hearing evaluation. If a child requires referral from hearing screening, a school nurse/teacher will complete the established protocol for the specialty telemedicine referral and send details asynchronously to an audiologist for consultation.
Study: NCT04888832

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Work requirement exemption months
Description: Cross-randomized intervention will test effect of additional exemption months before work requirements in SNAP become binding and extensions of the standard SNAP recertification period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Work requirement exemption months
Description: Cross-randomized intervention will test effect of additional exemption months before work requirements in SNAP become binding and extensions of the standard SNAP recertification period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Work requirement exemption months
Description: Cross-randomized intervention will test effect of additional exemption months before work requirements in SNAP become binding and extensions of the standard SNAP recertification period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Work requirement exemption months
Description: Cross-randomized intervention will test effect of additional exemption months before work requirements in SNAP become binding and extensions of the standard SNAP recertification period.
Study: NCT06498843

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: administration of an isotonic seawater solution (9g/L) in the nose
Description: 1. pump spray group : people with an upper respiratory tract infection (cold, rhinitis, rhinopharyngitis, and other upper respiratory infections/conditions).~2. sprays per nostril, at least 2 times a day up to 6 times a day. For 7 days

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: administration of a hypertonic seawater solution (21g/L) in the nose
Description: 1. pump spray group : people with an upper respiratory tract infection (cold, rhinitis, rhinopharyngitis and other upper respiratory infections/conditions).~2. sprays per nostril, at least 2 times a day up to 6 times a day. For 7 days
Study: NCT06357611

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Simulated technique
Description: The participant was in a supine position, with her upper limbs at her sides and her neck in a neutral position.~The researcher sat in a cephalic position, making contact with the participant's shoulders, without any movement, until 5 minutes had elapsed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle energy technique
Description: The participant was in a supine position, with her upper limbs alongside her body and her neck in a neutral position.~The researcher adopted a position homolateral to the dominant limb, contacting the lower limb with the caudal hand in the region of the malleoli. He then helped the participant to perform the movement, which consisted of flexing the hip and extending the knee passively until the motor barrier was reached, and instructed her to perform an isometric contraction of the hamstrings. She was asked to perform three 7-second contractions with a 2 to 3-second interval, using approximately 20% of her maximum strength, gaining a new motor barrier between each set, for a total of three sets.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 4th ventricle technique and muscular energy technique
Description: The participant was in a supine position, with her upper limbs alongside her body and her neck in a neutral position.~For CV-4, the researcher contacted the squamous portion of the occiput laterally, bringing it close to the posterior convexity of the occiput, bringing the skull into extension, changing the compression movement with decompression, until 3 minutes had elapsed.~For the MET, the researcher adopted a position homolateral to the dominant limb, contacting the lower limb with the caudal hand in the region of the malleoli. She then helped the participant to perform the movement, which consisted of flexing the hip and extending the knee passively to the motor barrier, having been instructed to perform an isometric contraction of the hamstring. A total of 3 7-second contractions with a 2-3 second interval were requested, using approximately 20% of her maximum strength, and with a new motor barrier being gained between each series, for a total of 3 series.
Study: NCT05454124

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Training visual sensitivity
Description: Investigators adopt a standard PL approach to train early visual processes of discriminating the orientation of Gabor patches presented at threshold contrast. Across training blocks, Gabors will range in spatial frequency, where contrast is adapted with a 3/1 staircase. Whenever a specific contrast threshold is reached, spatial frequency will increase by 2 cycles per degree and contrast will be reset. Preliminary data from this method in normally seeing and MD participants show both feasibility and tentative evidence that this training gives rise to improvements in acuity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Combination training
Description: Daily tasks involve a combination of being sensitive to basic visual features, being able to integrate these features, and directing attention and eye movements to better evaluate the information of potential interest. To address this integrative nature of real-world vision, this condition combines elements of training visual sensitivity, spatial integration, and spatial attention.
Study: NCT06602739

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGN5715
Description: Administered per protocol

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered per protocol
Study: NCT05931614

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unlimited fluid restrictions
Description: Patients are recommended unlimited fluid intake