TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06679101

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lenalidomide
Description: Lenalidomide will be administered.
Study: NCT06454929

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: operative
Description: open reduction : fixation by k-wires or screws

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: non-operative
Description: close reduction : by cast Immobilization
Study: NCT05141513

Intervention type: RADIATION
Group type: OTHER
Intervention: High Dose Rate Brachytherapy (HDR) Intraoperative Radiation Therapy (IORT)
Description: After the patient receives standard of care treatment, they will receive a single dose of radiation (15 Gy) at the time the tumor is surgically removed. Surgeons will then place clips along the blood vessels around the surgical area. These clips will be used to confirm (after surgery) that the expected dose of radiation was received during surgery.
Study: NCT06679101

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone will be administered.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Dexamethasone will be administered.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Daratumumab
Description: Daratumumab will be administered.
Study: NCT06607640

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Increase outdoor activity time during specific time periods
Description: The specific time periods of outdoor activity found to be beneficial for myopia prevention will be used as the intervention target, and a one-year intervention will be initiated.
Study: NCT04865731

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dermaprazole
Description: Patients will be managed with twice daily prophylactic use of the proposed intervention (Dermaprazole) topical cream for radiation dermatitis. The amount of cream will be 2cc per application and will be measured in pre-filled capped syringes for every application.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aquaphor
Description: Patients will be managed with twice daily prophylactic use of Aquaphor. The amount of Aquaphor will be 2cc per application and will be measured in pre-filled capped syringes for every application.
Study: NCT06757127

Intervention type: OTHER
Group type: OTHER
Intervention: ERAS Protocol Adaptation for Emergency Laparotomy
Description: The intervention incorporated a comprehensive quality improvement approach, including a presentation, live demonstrations, and an instructional video to support the implementation of ERAS protocols. These methods emphasized the key components outlined by the ERAS ® Society guidelines for emergency laparotomy, ensuring that participants understood the importance of each protocol step and its application in clinical practice. As part of the quality improvement initiative, efforts were made to engage key stakeholders, including local governance and healthcare authorities, to align the intervention with policy frameworks. Training materials, including videos and manuals, were reviewed by a consultant surgeon to ensure accuracy and relevance. Additionally, a consultant surgeon conducted individual demonstrations in the operating room and ward, supplemented by weekly morning meetings with nurses, anesthesiologists, residents, and doctors for one month.
Study: NCT06758843

Intervention type: OTHER
Intervention: measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month
Description: the intervention is follow-up with parameters to measure and data to record
Study: NCT04758754

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Training
Description: 8-weeks iso-volume active (SLKE) or passive static stretching training (PST) involving lower limb muscles

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training
Description: 8-weeks iso-volume active (SLKE) or passive static stretching training (PST) involving lower limb muscles
Study: NCT05475717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alprostadil liposome injection
Description: Alprostadil liposome injection, iv drip, QD×4 days (1 to 3 hours before surgery and 3 days after surgery)
Study: NCT05699395

Intervention type: DIAGNOSTIC_TEST
Intervention: Non interventional
Description: No intervention

Intervention type: DIAGNOSTIC_TEST
Intervention: Non interventional
Description: No intervention
Study: NCT04481581

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Alerts
Description: When FiO2 remains =\>0.4 and SpO2 =\>94% for more than 45 minutes, an electronic health record based alert will be sent to respiratory therapists to titrate oxygen per decision support tool.
Study: NCT06762535

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: repetitive transcranial magnetic stimulation
Description: Those receiving experimental treatment will receive 10 sessions of rTMS, stimulation protocol included 10 sessions within 14 days (once a day, 5 days/week, 2 weeks, 10 Hz frequency, pulse intensity 100% of the resting motor threshold, 50 pulses per train, inter train pause of 10 s, 40 stimulation trains, 2000 pulses/ session)

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham repetitive transcranial magnetic stimulation
Description: Those receiving experimental treatment will receive 10 sessions of rTMS, stimulation protocol included 10 sessions within 14 days (once a day, 5 days/week, 2 weeks, 10 Hz frequency, pulse intensity 100% of the resting motor threshold, 50 pulses per train, inter train pause of 10 s, 40 stimulation trains, 2000 pulses/ session).But there's no real pulse output,Just set the same conditions.
Study: NCT06761924

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-Guided Thoracic Paravertebral nerve block
Description: The patients will receive ultrasound-guided TPVB with 25 mg bupivacaine 0.5%, plus 8 mg dexamethasone (10 mL volume)

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Ultrasound-Guided Thoracic Paravertebral nerve block
Description: ultrasound-guided TPVB with 10 mL of saline without knowing which treatment they are receiving, maintaining blinding throughout the study.
Study: NCT06762002

Intervention type: OTHER
Intervention: blood sample
Description: After signature of consent form,blood samples will be collected for full blood cell count;classical autoimmune investigations, immunophenotyping;auto-Abs against type IIFNs, other cytokines, or other target proteins ,Genetic explorations by whole-exome or whole-genome sequencing;Biobanking
Study: NCT06760650

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Fluorescein angiography
Description: Fluorescein angiography
Study: NCT06761456

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Providing training models
Description: The experimental group was trained using the Clinical Education Module on 3 Parenteral Interventions in the Nursing Fundamentals laboratory.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The control group was trained using standard training models.
Study: NCT05496452

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beta-lactoglobulin
Description: Beta-lactoglobulin (BLG) will be administered thrice daily during a 7 day period of prehabilitation and 5 day period of immobilisation when the leg is placed in a brace.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Carbohydrate
Description: Carbohydrate (dextrose monohydrate) will be administered thrice daily during a 7 day period of prehabilitation and 5 day period of immobilisation when the leg is placed in a brace.
Study: NCT06457230

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 10Hz rTMS based on cerebellum and FPC
Description: We compare the efficacy of paired-pulse stimulation relative to single-pulse stimulation. Subjects will be randomly assigned to a cerebellar + frontal pole paired-pulse experimental group.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 10Hz rTMS based on cerebellum or FPC
Description: Subjects will be randomly assigned to a cerebellar or frontal pole randomised control group.
Study: NCT05730543

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Volbella or Juvederm Ultra XC filler
Description: Hyaluronic acid filler
Study: NCT06552481

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NP-PWD
Description: Application of NP-PWD device.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Wound Vac
Description: Application of wound vac device.
Study: NCT04965974

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital blue light blocking filter
Description: digital blue light blocking filter will be given to 80 dry eye subjects in mobile phones and laptops and 80 individuals will be without filters digital devices users

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital blue light blocking filter
Description: digital blue light blocking filter will be given to 80 dry eye subjects in mobile phones and laptops and 80 individuals will be without filters digital devices users
Study: NCT05098938

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acyclovir 50mg buccal/topical tablet, BAYM008894/UI1614773
Description: Oral (upper gum area), 50mg, 1 tablet.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral (upper gum area), 1 table.
Study: NCT05345067

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Laughter yoga session parts-1
Description: Section 1: Deep breathing exercises: A deep breath is taken as far as possible by raising the arms up to the sky. Breathing is held for 4-5 seconds after deep inspiration. Breathing is performed rhythmically and slowly, while the arms are placed in a normal position. After deep inspiration, one can exhale either by forming the lips in the whistling position or by laughing. In each deep breathing exercise technique, the expiration time of the exhalation process should be longer than the inspiration time.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Laughter yoga session parts-2
Description: Section 2: Warm-up exercises (10 minutes): Hands are clapped by holding parallel to each other. The fingertips and the palms touch each other, stimulating the acupuncture points on both hands, and the individual's energy level rises. In order to further raise the energy level and synchronize the movements of the group, a rhythm is added in the form of 1-2, 1-2-3. After several rhythmic hand-clapping movements, one more movement is added. Hands are clapped by swinging left and right. Then, an audible rhythm in the form of ho, ho, ha-ha-ha is also added to the hand-clapping movement. People in the group look at each other, and smile.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Laughter yoga session parts-3
Description: Section 3: Childish games (10 minutes): Childish games are used that will help to laugh for no reason, just like a child. Imagining these games and plays, the arms are raised upwards in the form of a Y with palms facing the sky, motivating the group by saying very good (clap), very good (clap), yes. The leader of laughter yoga speaks out very good (clap), very good (clap), hey (arms to the right and left) to keep the group's energy high and generate enthusiasm in the deep breathing exercises and laughter exercises sections. According to the energy and desire of the group, this section is completed after about 10 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Laughter yoga session parts-4
Description: Section 4: Laughter exercises (15 minutes): This section contains a variety of laughter exercises that will laugh, such as greetings, laughter cream, exploding balloon laughter, preparing and drinking strawberry milk, bonuses, hot soup, lion, aloha, bird, appreciation, elevator, and cream pie. A laugh is raised by doing only laughter exercises for no reason at all. At the end of this section, relaxation is achieved for about three minutes using deep breathing exercises. The group is given verbal guidance Put your hand on your heart, feel your heartbeat, let's exhale with a smile, make a wish or pray, smile as if we had achieved our wish, and the laughter yoga session is terminated.
Study: NCT05357989

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: buntanetap/posiphen
Description: HPMC (vegetarian source) capsule shells

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: buntanetap/posiphen
Description: HPMC (vegetarian source) capsule shells

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: HPMC (vegetarian source) capsule shells
Study: NCT05565573

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Medroxyprogesterone Acetate 500 MG Oral Tablet
Description: 500mg/ Pfizer Active ingredient: Medroxyprogesterone Acetate At a dosage of 500 mg/day

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Levonorgestrel-Releasing Intrauterine System
Description: Uterine cavity insertion
Study: NCT05950061

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sertraline
Description: Sertraline (200 mg/day) capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram
Description: Escitalopram (10 mg/day) capsule
Study: NCT06142513

Intervention type: OTHER
Intervention: Assessment
Description: Between December 2023 and June 204, 46 volunteer participants aged 18 years and older who met the inclusion criteria and were followed up at Istanbul University, Istanbul Faculty of Medicine, Department of Chest Diseases and Istanbul Faculty of Medicine, Department of Internal Medicine were included in the project. Participants' body composition, comorbidities, exercise capacity, peripheral muscle strength, sleep quality and quality of life were assessed.

Intervention type: OTHER
Intervention: Assessment
Description: Between December 2023 and June 204, 46 volunteer participants aged 18 years and older who met the inclusion criteria and were followed up at Istanbul University, Istanbul Faculty of Medicine, Department of Chest Diseases and Istanbul Faculty of Medicine, Department of Internal Medicine were included in the project. Participants' body composition, comorbidities, exercise capacity, peripheral muscle strength, sleep quality and quality of life were assessed.
Study: NCT05676151

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music Therapy
Description: 20-minute music-therapy-informed interventions (musical bingo, songwriting, lyric scramble) guided by a music therapist
Study: NCT04695054

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Buzzy device plus EMLA cream
Description: EMLA cream will be applied 60 minutes before the needle procedure; the Buzzy device will be used during the procedure

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Only EMLA cream
Description: EMLA cream will be applied 60 minutes before the needle procedure
Study: NCT05475717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alprostadil liposome injection
Description: Alprostadil liposome injection, iv drip, QD×4 days (1 to 3 hours before surgery and 3 days after surgery)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alprostadil liposome injection
Description: Alprostadil liposome injection, iv drip, QD×4 days (1 to 3 hours before surgery and 3 days after surgery)
Study: NCT05577936

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: XPERIENCE Advanced Surgical Irrigation
Description: A clear, colorless, aqueous solution that is indicated for use in the cleansing and removal of debris, including microorganisms, from wounds. Soak for 3 minutes for a total volume of 1L

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Irrigation
Description: 17.5 mL povidone-iodine with 500 mL normal saline: solution (0.35%) for 3 minutes for a total volume of 1L (including a normal saline rinse)
Study: NCT05811273

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical readiness training
Description: Bend and Reach:5 repetitions, Rear Lunge:5 repetitions per leg, High Jumper:5 repetitions, Rower:5 repetitions, Squat Bender:5 repetitions, Windmill:5 repetitions, Forward Lunge:5 repetitions per leg, Prone Row:5 repetitions, Bent-Leg Body Twist:5 repetitions per side, Push-Up:5 repetitions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: general exercises
Study: NCT05590559

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Opiates

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided erector spinae plane block
Description: PVB
Study: NCT05758584

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Vibrating tourniquet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Distraction card
Description: Distraction card
Study: NCT05400161

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MoodGym
Description: Participants in the control group will be enrolled in MoodGym, an evidence-based online Cognitive Behavioral Therapy (CBT) program for depression. Through the MoodGym program, participants will have access to interactive exercises, workbooks, anxiety and depression quizzes, and downloadable relaxation audio files. Investigators will supplement Moodgym with a facilitator contact by texting or email to check-in and encourage completion of intervention. MoodGym will provide information on the number of sessions completed by participants (engagement and dosage).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MoodGym
Description: Participants in the control group will be enrolled in MoodGym, an evidence-based online Cognitive Behavioral Therapy (CBT) program for depression. Through the MoodGym program, participants will have access to interactive exercises, workbooks, anxiety and depression quizzes, and downloadable relaxation audio files. Investigators will supplement Moodgym with a facilitator contact by texting or email to check-in and encourage completion of intervention. MoodGym will provide information on the number of sessions completed by participants (engagement and dosage).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Media-Based Parenting Program
Description: Participants in the intervention group will be enrolled in Facebook secret user groups, administered by a trained facilitator, to permit participants to view and comment on posted materials. Content and user identity are restricted to invited participants to maintain privacy. Investigators will organize educational materials into video vignettes, narrated PowerPoint presentations, and written materials. The facilitator reviews and comments on postings daily and provides feedback to participants. Facebook analytics for the secret groups are available to group administrators and will provide information on any sessions viewed and counts of sessions viewed and comments posted. Participants randomized to the intervention will also have the option to take part in a preliminary virtual session through a secure video platform (e.g. BlueJeans) and will receive weekly engagement text messages. Women in the intervention group will be enrolled in the online depression treatment program, MoodGym.
Study: NCT04809376

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentosan Polysulfate Sodium twice weekly
Description: Subcutaneous Injection, 1.5mg/kg Ideal body Weight (IBW)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (Sodium Chloride Injection, 0.9%)
Description: Placebo to match PPS

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (Sodium Chloride Injection, 0.9%)
Description: Placebo to match PPS

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Sodium Chloride Injection, 0.9%)
Description: Placebo to match PPS

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentosan Polysulfate Sodium Fixed Dose
Description: Subcutaneous Injection, 100/150/180 mg if \<65kg/ ≥ 65 kg and ≤ 90kg/ \>90 kg IBW

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentosan Polysulfate Sodium once weekly
Description: Subcutaneous Injection, 2.0mg/kg Ideal body Weight (IBW)
Study: NCT05001126

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIFT 1x/week
Description: HIFT is a time-efficient modality of exercise combining high-intensity aerobic and resistance training using minimal equipment. HIFT 1x/week represents a dose of one HIFT workout per week.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIFT 2x/week
Description: HIFT is a time-efficient modality of exercise combining high-intensity aerobic and resistance training using minimal equipment. HIFT 2x/week represents a dose of two HIFT workouts per week.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIFT 3x/week
Description: HIFT is a time-efficient modality of exercise combining high-intensity aerobic and resistance training using minimal equipment. HIFT 3x/week represents a dose of three HIFT workouts per week.
Study: NCT04603300

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: INT301
Description: INT301 is an allergy immunotherapy delivered in the form of a fully functional toothpaste

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Fully functional toothpaste containing no immunotherapy agents
Study: NCT04309188

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Senaptec Strobe Glasses
Description: The glasses use liquid crystal technology that causes a flicker from clear to opaque to enhance vision.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard softball drills
Description: Control group, which will perform normal hitting and fielding drills without stroboscopic training
Study: NCT04950920

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Y-2 sublingual tablets
Description: 30mg Edaravone+6mg d-borneo OR， Bid

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: d-borneol
Description: 60 μg d-borneol OR， Bid
Study: NCT05715632

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carrelizumab combined with XELOX
Description: Before surgery, the patient received standard dose of carrelizumab combined with XELOX regimen for 4 courses of treatment, and within 3-4 weeks after the completion of the fourth administration, preoperative imaging examination was conducted to evaluate the efficacy of new adjuvant treatment and the possibility of radical D2 resection, and to receive radical hand surgery for gastric cancer
Study: NCT05062343

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dilapan-S
Description: Osmotic dilator

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cook Cervical Ripening Balloon
Description: Double balloon catheter for cervical ripening
Study: NCT06399978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brain Blossom - Gamified Differential Outcome Training
Description: Digital cognitive training with a gamified DOT task for 20 minutes per day 3-4 times a week for 6-8 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gamified Non-Differential Outcome Training
Description: Digital cognitive training with a gamified NDOT task for 20 minutes per day 3-4 times a week for 6-8 weeks.