TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06373874

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Heel blood collection in a newborn simulation model
Description: The person who will take heel blood in the newborn simulation model can prepare the materials.~Firstly, the blood sample can fill in all the information on the filter paper. Knows where the baby's face should be. It can determine the area where a heel blood sample can be taken.It can gently warm the heel area for a few minutes. The area can be cleaned with alcoholic preparation (cotton/swab, etc.). He can squeeze the heel with his thumb and index finger in front. The other 3 fingers can be rubbed at the back. May stroke the heel three times. The heel can be pierced once with a lancet at a suitable location. He can relax his hand. He can wipe away the first drop of blood. It can create a large thick drop of blood to be collected on filter paper. It can make the drop fill the entire ring on the filter paper with one touch. After the procedure is completed, the heel can be pressed.
Study: NCT04744974

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diet intervention
Description: Participants will be given dietician counseling on their assigned diet

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diet intervention
Description: Participants will be given dietician counseling on their assigned diet
Study: NCT06333197

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ORIF through transparotid approach
Description: The Retromandibular Transparotid approach is a surgical method used to access structures in the parotid gland region by making an incision behind the mandible.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ORIF through retroparotid approach
Description: The Retromandibular Retroparotid approach, also known as the Modified Blair Incision, is a surgical technique used to access structures within the parotid gland region by creating an incision behind the mandible and extending it into the parotid region.
Study: NCT06472986

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activity-based therapy and transcutaneous spinal cord stimulation
Description: Activity Based Therapy (ABT) is a method of neuro-rehabilitation that incorporates a high intensity, long duration and effortful engagement from the individual receiving therapy, to garner improvements in sensory and motor function. The ABT constitutes 4 types of exercises including: cardio-fitness, resistance, postural/weightbearing and functional exercises. TransCutaneous Spinal Cord Stimulation (TCSCS) stimulates spinal networks in the cervical region to neuro-modulate the descending motor commands/motor intentions from the brain, which control the muscles. In tCSCS, electrical stimulation is delivered at a frequency of 30-50Hz at 500-1000µs between C3-C7. 12 sessions of ABT (4 weeks), followed by 28 sessions of ABT-TCSCS (7 weeks). Each session will last 1 hour and delivered 3 times per week.
Study: NCT05323825

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: Fermented milk product containing a probiotic

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Product with identical characteristics to the experimental product.
Study: NCT05045989

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Residence-based testing participation pilot (SARS-CoV-2 testing with relaxed social distancing restrictions)
Description: SARS-CoV-2 asymptomatic saliva testing (as available to all students at staff at the participating university) delivered with relaxed social distancing (behavioural element) in two halls of residence.
Study: NCT06457672

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Group I
Description: Complete Crown technique of superimposition

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Group II
Description: Gold standard technique of superimposition
Study: NCT04717830

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gamezumab
Description: solution for infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gamezumab
Description: solution for infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gamezumab
Description: solution for infusion
Study: NCT06272331

Intervention type: OTHER
Group type: OTHER
Intervention: Low-protein plant-based drink
Description: Ingestion of a low-protein plant-based drink

Intervention type: OTHER
Group type: OTHER
Intervention: High-protein plant-based drink
Description: Ingestion of a high-protein plant-based drink

Intervention type: OTHER
Group type: OTHER
Intervention: Cow's milk
Description: Ingestion of cow's milk
Study: NCT04285320

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravesical antibiotic instillation
Description: Based on the participant's allergy and antibiotic resistance profile, one of the following three antibiotics will be instilled intravesically via a latex free BARD® 12 French Foley catheter for a total of 6-8 instillations (2 instillations/week) according to the Atlantic Health System Urogynecology Division antibiotic bladder instillation standard protocol:~* Amikacin-30 mg in 60 ml of sterile water~* Gentamycin-80mg in 60ml sterile water~* Tobramycin-80 mg in 100 ml of sterile water

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antibiotic oral suppressive therapy
Description: In the antibiotic oral suppression therapy arm, one of the following routinely used antibiotics will be prescribed for a total of 3 months according to the American Urogynecology Society Guidelines and based on the participant's allergy and antibiotic resistance profile:~* Trimethoprim daily (100 mg)~* Trimethoprim/sulfamethoxazole daily (40 mg/200 mg)~* Trimethoprim/sulfamethoxazole every 3 days (40 mg/200 mg)~* Nitrofurantoin monohydrate/macrocrystals daily (50 mg)~* Nitrofurantoin monohydrate/macrocrystals daily (100 mg)~* Cephalexin daily (125 mg)~* Cephalexin daily (250 mg)~* Fosfomycin every 10 days (3 grams)
Study: NCT06144762

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological/Vaccine: Blood sample and tissue sample
Description: During the surgery :~Tissus sample : primary tumor and metastasis blood sample : 3 EDTA tubes ex vivo MRI data
Study: NCT06433856

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion
Description: Cold water immersion consists in 12 min standing in 10 °C water

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percussive Massage Therapy
Description: Percussive massage therapy is performed with a massage gun on the thigh muscles for 12 min
Study: NCT05736575

Intervention type: GENETIC
Intervention: BDNF analysis (Elisa KIT)
Description: Analysis of peripheral BDNF will be performed

Intervention type: GENETIC
Intervention: BDNF analysis (Elisa KIT)
Description: Analysis of peripheral BDNF will be performed
Study: NCT05698875

Intervention type: OTHER
Group type: OTHER
Intervention: High glycaemic load breakfast meal
Description: Breakfast meal

Intervention type: OTHER
Group type: OTHER
Intervention: High glycaemic load breakfast meal with additional 10g protein
Description: Breakfast meal

Intervention type: OTHER
Group type: OTHER
Intervention: Medium glycaemic load breakfast meal
Description: Breakfast meal
Study: NCT04851093

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCM granule plus conventional drug
Description: All patients will receive conventional drug according to 2020 Global Initiative for Chronic Obstructive Lung Disease (GOLD) and Chinese Medicine Diagnosis Treatment Guidelines.~Yiqiwenfei granule for qi deficiency and internal cold fluid syndrome.~Fuzhengqinghua granule for qi and yin deficiency and unclean phlegm heat syndrome.~Fuzhengzaohua granule for lung and spleen qi deficiency and phlegm-damp amassing in lung syndrome.~TCM granule (Jiangyin Tian Jiang Pharmaceutical Co.,Ltd, 10g/packet) will be administered twice daily for 8 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: TCM placebo granule plus conventional drug
Description: All patients will receive conventional drug according to 2020 Global Initiative for Chronic Obstructive Lung Disease (GOLD) and Chinese Medicine Diagnosis Treatment Guidelines.~Placebo Yiqiwenfei granule for qi deficiency and internal cold fluid syndrome.~Placebo Fuzhengqinghua granule for qi and yin deficiency and unclean phlegm heat syndrome.~Placebo Fuzhengzaohua granule for lung and spleen qi deficiency and phlegm-damp amassing in lung syndrome.~TCM placebo granule (Jiangyin Tian Jiang Pharmaceutical Co.,Ltd, 10g/packet) will be administered twice daily for 8 weeks.~The appearance, weight, color and odor of the preparation are the same as those of experimental group.~The placebo granule consists of dextrin, bitter and 5% of the TCM granule.
Study: NCT05849961

Intervention type: DEVICE
Intervention: Exactech Hip Systems
Description: The Exactech Hip System comprises a fixed-bearing hip joint prostheses used in treating human hip joint diseases as part of THA. These prostheses include a combination of the components and are available in a range of sizes to accommodate varying anatomical requirements.

Intervention type: DEVICE
Intervention: Exactech Hip Systems
Description: The Exactech Hip System comprises a fixed-bearing hip joint prostheses used in treating human hip joint diseases as part of THA. These prostheses include a combination of the components and are available in a range of sizes to accommodate varying anatomical requirements.
Study: NCT05947240

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aerobic exercises
Description: The treatment group patients will perform upper extremity aerobic exercises by using an arm ergometer under the supervision of a physiotherapist.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: active alternating movements for the upper limbs
Description: The control group patients will perform functional active alternating movements for the upper limbs at home involving three sets with 10 repetitions and a rest interval between 1- and 2-minute. Intervention will be for 3 times a week or 6 weeks.
Study: NCT04133077

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: blood samples collection
Description: Serology and genetic analyses will be performed in patients blood samples
Study: NCT04480151

Intervention type: OTHER
Intervention: standard of care
Description: retrospective study: standard of care

Intervention type: OTHER
Intervention: standard of care
Description: retrospective study: standard of care
Study: NCT05849961

Intervention type: DEVICE
Intervention: Exactech Hip Systems
Description: The Exactech Hip System comprises a fixed-bearing hip joint prostheses used in treating human hip joint diseases as part of THA. These prostheses include a combination of the components and are available in a range of sizes to accommodate varying anatomical requirements.
Study: NCT06217614

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: (Manuka honey-green tea)
Description: Manuka honey is a natural honey, and green tea are herbs Dried green tea leaves (100 gm) will be soaked into 500 ml of methanol solution for two days. Green tea plus ginger mouthwash was prepared by adding 50% green tea extract and 50% ginger extract. After extraction, the extract was filtered and taker to the vacuum evaporator to remove the solvent.~The mouthwash was prepared by adding 3 gm of each extract, 0.12 gm sodium saccharin, and one liter distilled water, then every 20 ml of Manuka honey were added in 100 ml of (green tea and ginger solution). Finally, the mixture was stirred vigorously until all the particles were dissolved. Thereafter the obtained mixture was filtered. The mouthwash then filled in sterilized amber color bottles of 250 ml each.~According to similar studies performed in this field, the patients used a 20ml of (Manuka honey-green tea- ginger) mouthwash three times a day (preferably after their meals), kept it for one minute, and then poured it out
Study: NCT05796830

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Puzzle application
Description: Five expert opinions will be taken for the puzzle application to be applied after the surgery, and the application and difficulty level of the puzzle will be decided.
Study: NCT04695613

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aminoacid
Description: amino acid infusion 150 ml/kg/hr starting preoperative

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium sulfate
Description: magnesium sulphate bolus and infusion 60 mg/kg starting preoperative
Study: NCT05721807

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: functional magnetic stimulation
Description: When applying functional magnetic stimulation, the stress urinary incontinence program P2 stress was chosen. The first 20 min. current frequency was 35 Hz, modulation - rising amplitude (from 0 to maximum per second), total wave duration 12 s. active time 6 s., pause time 6 s. After 20 min. current frequency changed to 5 Hz, modulation and wave remained the same. After 2 min. current frequency changed to 35 Hz, modulation - amplitude, one-sided sinusoidal, wave remained the same. The total duration of the procedure was 30 min. A magnetic spring is installed at the bottom of the chair. During the treatment, each subject was instructed to sit on a chair so that the perineum was centered on the spring and that the subjects felt the contraction of the muscles. The intensity of the magnetic field was adjusted so as to feel comfortable during the study procedure (Vadalà et al., 2017).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pelvic floor muscle training program
Description: The program consisted of two parts. From procedures 1 to 6, 6 exercises were performed, after 6 times the exercises were adjusted, and from procedures 7 to 12, another 5 exercises were performed. The program consists of breathing, pelvic floor muscle strength, endurance, speed training exercises and exercises to strengthen the thighs, buttocks, deep back and deep abdominal muscles. Exercises were performed in 2 sets of 10 repetitions at an intensity from various positions: lying on the back, side, sitting, quadruped (Oliveira et al., 2017; Walton et al., 2019).
Study: NCT05667415

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disulfiram and cisplatin
Description: on the first day of treatment, patients were given intravenous drip of 80mg/m2 cisplatin, and 21 days was a course of treatment, lasting for 6 courses. Take 400mg disulfiram orally every day, and continue to use it until the end of chemotherapy. According to the patient's tolerance to disulfiram, the dose of disulfiram can be re-evaluated during the treatment, and the lowest dose is 125mg per day. The clinical symptoms, signs and adverse reactions of patients were observed, and the treatment effect of patients was evaluated after two consecutive cycles with 3 weeks as a cycle.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cisplatin
Description: on the first day of treatment, patients were given 80mg/m2 cisplatin intravenously, and 21 days was a course of treatment, lasting for 6 courses.
Study: NCT06217614

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: (Manuka honey-green tea)
Description: Manuka honey is a natural honey, and green tea are herbs Dried green tea leaves (100 gm) will be soaked into 500 ml of methanol solution for two days. Green tea plus ginger mouthwash was prepared by adding 50% green tea extract and 50% ginger extract. After extraction, the extract was filtered and taker to the vacuum evaporator to remove the solvent.~The mouthwash was prepared by adding 3 gm of each extract, 0.12 gm sodium saccharin, and one liter distilled water, then every 20 ml of Manuka honey were added in 100 ml of (green tea and ginger solution). Finally, the mixture was stirred vigorously until all the particles were dissolved. Thereafter the obtained mixture was filtered. The mouthwash then filled in sterilized amber color bottles of 250 ml each.~According to similar studies performed in this field, the patients used a 20ml of (Manuka honey-green tea- ginger) mouthwash three times a day (preferably after their meals), kept it for one minute, and then poured it out
Study: NCT04976270

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLPG3667
Description: GLPG3667 capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLPG3667
Description: GLPG3667 capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo capsules
Study: NCT05999604

Intervention type: DRUG
Group type: OTHER
Intervention: Ocrelizumab Injection [Ocrevus]
Description: Semestrial administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ocrelizumab Injection [Ocrevus]
Description: Annual administration
Study: NCT05262348

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: adaptive DBS delivered through AlphaDBS IPG System
Description: The AlphaDBS IPG System delivers both conventional DBS and adaptive DBS. Adaptive DBS is a programming mode that provides stimulation in a closed-loop adaptive real-time fashion, using a biosignal recorded from the same macro-electrodes routinely implanted for DBS as an input variable.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: conventional DBS delivered through AlphaDBS IPG System
Description: The AlphaDBS IPG System delivers both conventional DBS and adaptive DBS. Conventional DBS is programmed by DBS specialists.
Study: NCT05444998

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intuzumab, pyrrolidone, nab-paclitaxel
Description: Pyrrolidone 400 mg, qd; nab-paclitaxel 125 mg/m2, qw, D1/8/15; inituzumab 6 mg/kg (first dose 8 mg/kg) q3w, D1; 4 cycles in total (q3w as 1 cycle).~The patient's postoperative adjuvant therapy was 4 cycles of epirubicin + cyclophosphamide + physician's choice of anti-HER2 targeted therapy.~Multiple drug interruptions for adverse events were allowed throughout.
Study: NCT05435820

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-infrared Transcranial Laser Therapy
Description: The treatment consists in exposing bilaterally the frontal brain to Transcranial Laser Therapy, which may enhance ATP production in depressed subjects.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-infrared Transcranial Laser Therapy
Description: The treatment consists in exposing bilaterally the frontal brain to Transcranial Laser Therapy, which may enhance ATP production in depressed subjects.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-infrared Transcranial Laser Therapy
Description: The treatment consists in exposing bilaterally the frontal brain to Transcranial Laser Therapy, which may enhance ATP production in depressed subjects.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Near-infrared Transcranial Laser Therapy
Description: The treatment consists in exposing bilaterally the frontal brain to Transcranial Laser Therapy, which may enhance ATP production in depressed subjects.
Study: NCT06226532

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lidocaine spray
Description: Group SL: Spray 10% lidocaine for 4 puffs at the endotracheal tube cuff, also prepare for spray at the laryngeal inlet for 4 puffs (total approximately 1.5mg/kg)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous Lidocaine
Description: 2% lidocaine 1.5 mg/kg IV will be given 2 minutes after cisatracurium injection (3 minutes prior intubation).
Study: NCT04992416

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: immediate implant placement with ATBG and SMV
Description: immediate implant placement using ATBG as a graft material, with SMV

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: immediate implant placement with ATBG
Description: immediate implant placement using ATBG as a graft material without SMV
Study: NCT05764369

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parenting Wisely Residential Treatment (PWRT)
Description: PWRT experimental intervention

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: TAU
Description: The TAU condition is the standard of care offered to parents in RT settings.
Study: NCT06450665

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR Social Avoidance Intervention
Description: The intervention is based on cognitive-behavioral approach with a virtual coach acting as the therapist. It will be designed in tandem with input from Hong Kong users to ensure the scenario can resonate with them. By testing beliefs that inhibit confidence in a safe and controlled environment, participants will complete tasks with increasing difficulty in three VR scenarios and learn that they can cope in situations that they previously avoid.
Study: NCT04825808

Intervention type: OTHER
Intervention: usual care
Description: according to recommendations
Study: NCT04881968

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hopewell Hospitalist Video Game
Description: Hopewell Hospitalist is a customized theory-based adventure video game that uses narrative engagement to educate physician players on advance care planning to increase physicians' likelihood of engaging in and billing for ACP conversations.
Study: NCT06300593

Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement and comparison of leucocytosis and concentrations of C-reactive protein (CRP), interleukin-1 (IL-1), IL-6, IL-10, Tumor Necrosis Factor (TNF-alpha) in PCOS phenotypes A, B, C and D
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare the above parameters of peripheral blood in the four study arms
Study: NCT06064422

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BeatIt-MV
Description: BeatIt-MV, designed to be implemented with minimally verbal autistic individuals, is an adaptation of BeatIt-2. The intervention aims to improve mood and decrease depressive symptoms through an increase in meaningful engagement in recreational, domestic, and social/leisure activities.
Study: NCT06204991

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ADP-TILIL7
Description: Autologous tumor infiltrating lymphocytes genemodified (by a lentiviral vector) to produce IL-7 upon antigen engagement

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Lymphodepleting Chemotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine Phosphate
Description: Lymphodepleting Chemotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proleukin
Description: IL-2
Study: NCT06562413

Intervention type: DRUG
Intervention: MAbs
Description: Monthly or quarterly mAbs administration

Intervention type: DRUG
Intervention: MAbs
Description: Monthly or quarterly mAbs administration