TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05388032

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sodium Reduction Intervention
Description: The sodium reduction intervention is a dietician-led behavioral intervention consisting of two phases, first a 3-month intensive intervention phase, followed by a 9-month maintenance phase. The overall goal of the intervention is to reduce sodium intake to \<2,300 mg per day based on the most recent guideline from the National Academies of Medicine. Both phases will include individual and group behavioral modification counseling designed to facilitate a reduction in dietary sodium intake.
Study: NCT05604521

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PfSPZ Vaccine
Description: PfSPZ vaccine consists of radiation-attenuated, aseptic, purified Plasmodium falciparum (NF54) sporozoites (SPZ) cryopreserved in liquid nitrogen vapor phase (LNVP) at -150C to - 196C. PfSPZ Vaccine is composed of PfSPZ derived from the NF54 strain of Pf, which is thought to be from West Africa. PfSPZ Vaccine is diluted in phosphate buffered saline (PBS) with human serum albumin (HSA) to achieve the correct dosage and is administered by DVI.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PfSPZ Vaccine
Description: PfSPZ vaccine consists of radiation-attenuated, aseptic, purified Plasmodium falciparum (NF54) sporozoites (SPZ) cryopreserved in liquid nitrogen vapor phase (LNVP) at -150C to - 196C. PfSPZ Vaccine is composed of PfSPZ derived from the NF54 strain of Pf, which is thought to be from West Africa. PfSPZ Vaccine is diluted in phosphate buffered saline (PBS) with human serum albumin (HSA) to achieve the correct dosage and is administered by DVI.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PfSPZ Challenge (7G8)
Description: PfSPZ Challenge (7G8) is similar to PfSPZ Vaccine but has not been attenuated by radiation and is therefore infectious.PfSPZ Challenge (7G8) is composed of PfSPZ derived from the 7G8 clone of Pf, which is from Brazil.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PfSPZ Challenge (7G8)
Description: PfSPZ Challenge (7G8) is similar to PfSPZ Vaccine but has not been attenuated by radiation and is therefore infectious.PfSPZ Challenge (7G8) is composed of PfSPZ derived from the 7G8 clone of Pf, which is from Brazil.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: PfSPZ Challenge (7G8)
Description: PfSPZ Challenge (7G8) is similar to PfSPZ Vaccine but has not been attenuated by radiation and is therefore infectious.PfSPZ Challenge (7G8) is composed of PfSPZ derived from the 7G8 clone of Pf, which is from Brazil.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: PfSPZ Challenge (7G8)
Description: PfSPZ Challenge (7G8) is similar to PfSPZ Vaccine but has not been attenuated by radiation and is therefore infectious.PfSPZ Challenge (7G8) is composed of PfSPZ derived from the 7G8 clone of Pf, which is from Brazil.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: 0.9% sodium chloride

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: 0.9% sodium chloride
Study: NCT05976698

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.5 h after the start of each study session the participants will be administered placebo per os in the form of vials containing 1ml 20% EtOH.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.5 h after the start of each study session the participants will be administered placebo per os in the form of vials containing 1ml 20% EtOH.
Study: NCT05724875

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FLASH RT
Description: For T1 (small) lesions: 22 Gy single dose FLASH RT; For T2 (large) lesions: 5 x 6 Gy fractionated dose FLASH RT
Study: NCT05825287

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Trained by teaching back method
Description: in chemotherapy symptom management training, 2 groups will be created and a group will be given normal symptom management training, and the other group will be trained by teaching back method to assess the symptom control and quality of life after the chemotherapy training that patients have received and evaluate the effect of the teaching back method
Study: NCT06184321

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Alteplase
Description: Instilled into IPC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Administration
Description: Instilled into IPC
Study: NCT05825287

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Management training
Description: Management training
Study: NCT05443984

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JP-1366 20mg
Description: 1 capsule of JP-1366 20 mg, 1 tablet of esomeprazole placebo (irrespective of meals)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Esomeprazole 40mg
Description: 1 capsule of JP-1366 placebo, 1 tablet of esomeprazole 40 mg placebo (irrespective of meals)
Study: NCT06022159

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients will receive the hypofractionated radiation therapy (30 Gy in 5 fractions) prior to surgery.
Description: Early post-radiotherapy toxicity will then be assessed 1 month after the end of radiotherapy.~Post-operative follow-up: post-operative complications will be followed at 3 and 6 weeks post-surgery.~A visit at 6 months post-surgery will also be carried out to evaluate post-operative complications and late adverse effects of radiotherapy.~Long-term follow-up would also be performed every 6 months from the 6-month post-surgery visit up to 3 years post-surgery (M12, M18, M24, M30 and M36).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patient will undergo surgery before receive the adjuvant hypofractionated radiation therapy (40 Gy in 15 fractions).
Description: Post-operative follow-up: postoperative complications will be followed at 3 and 6 weeks post-surgery (before the start of irradiation). Early post-radiotherapy toxicity will then be assessed 1 month after the end of radiotherapy.~A 6-month post-surgery check-up will also be carried out to assess post-operative complications and acute side effects of radiotherapy.~Long-term follow-up would also be performed every 6 months from the 6-month post-surgery visit up to 3 years post-surgery (M12, M18, M24, M30 and M36).
Study: NCT05852353

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Pediatric Bladder Health Patient Education Curriculum
Description: Bladder Basics is designed to be a digital health intervention to improve knowledge of healthy bladder practices. It is a video-based bladder health curriculum based on 1) principles of Urotherapy 2) stakeholder need for a gold-standard resource 3) behavioral change theory 4) education design standards for inclusion as a comprehensive school health program (CSHP).~The overall mission of the course is to teach children and their families about pediatric bladder health. The development of the course has followed the NIH's Clear \& Simple standards for patient education. The 7 video lesson plan spans 60 minutes total. The course is designed to support families awaiting medical care, which would provide the continued support. In addition, one lesson shares solutions to common home and school-based barriers to behavioral change. The 4 healthy bladder practices that are promoted are- 1) pee every 3 hours 2) drinking water 3) daily poop without straining 4) toilet postures.
Study: NCT05520476

Intervention type: DEVICE
Intervention: Neuroliten MVP system
Description: The Neuroliten MVP system will be an App that gets uploaded to the patients iPhone from the App Store.
Study: NCT04704089

Intervention type: OTHER
Intervention: spectrophotometer
Description: * Calibration of the spectrophotometer (calibration of white and green color on the provided support),~* Placing the patient or witness in the chair,~* Placement of intraoral retractors,~* Photographs of the dental arch in occlusion as well as slightly open mouth to visualize the mandibular incisors,~* If MIH is suspected, occlusal images of the occlusal surfaces of the first molars will be taken with the help of a dental mirror,~* Shooting with the spectrophotometer centered on each of the teeth of interest in the anterior sector with verification of the good quality of the shot according to the axis (validated in green on the camera),~* Backup of images with coded identification number

Intervention type: OTHER
Intervention: Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses
Description: * Chemical analysis of enamel mineral.~* Techniques of spectrometry and spectroscopy (Raman and FTIR)~* Atomic Probe Tomography and Protein Mass Spectrometry (ICP-MS).
Study: NCT05673616

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mckenzie Extension Exercises
Description: After two weeks of initial consultation, the patient will be taught to perform slouch-overcorrect on day 1 followed by flexion on day 2 in lying position and accompanied by flexion for 5 days in sitting position and finally flexion in standing will be performed.~The exercises will be repeated for 10 times and followed by extension in standing exercises.
Study: NCT06471127

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pseudoword learning paradigm task
Description: Pseudoword learning is an experimental learning task by which participants view two novel objects (a target and a foil) and simultaneously hear an audio recording of the pseudoword name of one of the two objects. Participants must choose (via mouse click) which object corresponds to the word presented, immediately after which feedback is provided.
Study: NCT05618509

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: STENDO session
Description: It is a combination enveloping the lower limbs up to the abdomen. The massage system induces pressure from the ankles to the abdomen between each heartbeat. The capacity for physical exercise is potentially improved.~STENDO : 45 minutes, 2 legs and the pelvis, pression of 65mm Hg
Study: NCT05724875

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional RT
Description: For T1 (small) lesions: 22 Gy single dose conventional RT; For T2 (large) lesions: 5 x 6 Gy fractionated dose conventional RT
Study: NCT05174273

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Fecal Microbiota Transplantation
Description: FMT is a technique in which intestinal microbiota are transferred from a healthy screened donor to a patient, with the goal being to introduce or restore a stable microbial community in the gut.
Study: NCT05961215

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Penguin Cold Cap
Description: Penguin cold cap: administered 60 minutes prior to melphalan infusion and continue for 5 hours after melphalan infusion start time, for a total of 6 hours, on Days -2 and -1.
Study: NCT06538935

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: adbelimumab
Description: adbelimumab：1200mg iv d1 q3w

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: adbelimumab
Description: adbelimumab：1200mg iv d1 q3w

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SBRT
Description: SBRT: SBRT: 8-30Gy/1-6F（dose is determined according to the tumor diameter）; tumor thrombus dose 30Gy /5-6F;
Study: NCT05618509

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: A six-minute walking distance test
Description: Before and after STENDO session, the patient has to walk 6 minutes in a flat corridor (30m long)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: A six-minute walking distance test
Description: Before and after STENDO session, the patient has to walk 6 minutes in a flat corridor (30m long)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Near Infrared Spectroscopy
Description: The goal is to measure the evolution of the oxygen consumption of the right leg during an effort on a bicycle at constant power for 5 minutes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Near Infrared Spectroscopy
Description: The goal is to measure the evolution of the oxygen consumption of the right leg during an effort on a bicycle at constant power for 5 minutes.
Study: NCT06441513

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chinese traditional medicine nursing combined with case tracking management
Description: First, we set up a team for the prevention of hand foot syndrome, including 1 head nurse of the tumor chemotherapy department, 2 doctors, 16 nurses (16 nurses were divided into 4 groups, each group designated a team leader) and the researchers of this experiment. Doctors are responsible for the diagnosis of HFS and the determination of traditional Chinese medicine prescriptions, head nurses and team leaders are responsible for quality control, and nurses are responsible for the assessment, intervention and evaluation of patients.

Intervention type: OTHER
Group type: OTHER
Intervention: Health Education
Description: elaborating the symptoms, mechanism and corresponding treatment measures of HFS for patients, reducing the fear of patients, helping them relax and adjust their mentality, and cooperating with observation.
Study: NCT06538935

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SBRT
Description: SBRT: SBRT: 8-30Gy/1-6F（dose is determined according to the tumor diameter）; tumor thrombus dose 30Gy /5-6F;
Study: NCT05323383

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Meditation
Description: Participants in the mindfulness meditation condition will listen to a 20minute guided mindfulness meditation practice that holds the breath and body as the object of meditation.
Study: NCT06538935

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: apatinib
Description: apatinib：250mg po, qd
Study: NCT05323383

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-hypnosis
Description: Participants in self-hypnosis will listen to a 20-minute audio-guided hypnosis practice with an induction phase, followed by suggestions tailored towards shifts in affect and decentering, and then a re-alerting with post-hypnotic suggestions phase.
Study: NCT06542445

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral CBD oil enriched with terpenes
Description: Stage I dosing, increasing titration:~days 1-2: 2.5 mg/kg BW/day; days 3-4: 5 mg/kg BW/day; day 5-7: 7.5 mg/kg BW/day; days 8-35: 10 mg/kg BW/day.~Stage II dosing, increasing titration:~days 36-37: 2.5 mg/kg BW/day; days 38-39: 5 mg/kg BW/day; day 40-42: 7.5 mg/kg BW/day; days 43-70:10 mg/kg BW/day.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oral Placebo
Description: Oral placebo oil that is similar in appearance and taste to the CBD oil. Titration and dosing identical to those described for the CBD oil.
Study: NCT05823194

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Fertility sparing surgery
Description: Sparing the uterus and/or ovaries of the patients suffering from gynecologic malignancies to keep the patients' fertility
Study: NCT05323383

Intervention type: OTHER
Group type: OTHER
Intervention: Attention Control
Description: Control participants will listen to a 20-minute natural history recording which was chosen as past research has found that individuals who listen to it report this to be a neutral, but relaxing passage, and it has been used as an effective control condition in previous research.
Study: NCT06459557

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: cast
Description: children with displaced distal radius fractures would be managed by a cast in the emergency room

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: surgical reduction
Description: anatomical reduction of pediatric displaced distal radius fractures under general anesthesia in the operating room
Study: NCT05618509

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: STENDO placebo
Description: STENDO placebo : 45 minutes, on 2 legs and the pelvis, pression of 10 mmHg
Study: NCT05982158

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Avatar therapy
Description: Seven 50-minute therapy sessions conducted by videoconferencing.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive behavioural therapy (CBT)
Description: Seven 50-minute therapy sessions conducted by videoconferencing.
Study: NCT06488417

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Frankincense essential oil + boswellic acid supplement
Description: This supplement contains frankincense essential oil and boswellic acid as its active ingredients.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Frankincense essential oil supplement
Description: This supplement contains frankincense essential oil as its active ingredient.
Study: NCT05415098

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: APG-5918
Description: The investigational drug product is formulated as oral tablets of 50 mg or 200 mg that contain APG-5918 as the active ingredient. APG-5918 will be orally administered once every day on 28-day cycles.~The dosage of APG-5918 depends on the dose level to which the patient is assigned. Each dose of APG-5918 will be taken orally in fasted condition in the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: APG-5918
Description: The investigational drug product is formulated as oral tablets of 50 mg or 200 mg that contain APG-5918 as the active ingredient. APG-5918 will be orally administered once every day on 28-day cycles.~The dosage of APG-5918 depends on the dose level to which the patient is assigned. Each dose of APG-5918 will be taken orally in fasted condition in the study.
Study: NCT05087017

Intervention type: OTHER
Intervention: Intervention group
Description: Patients with medical condition to follow the rehabilitation program will be asked to answer questionnaires to assess their sleep quality.
Study: NCT05676385

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: First concept product (containing 50 grams of carbohydrates)
Description: Fasted intake of First concept product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: First concept product (containing 50 grams of carbohydrates)
Description: Fasted intake of First concept product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: First concept product (containing 50 grams of carbohydrates)
Description: Fasted intake of First concept product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Second concept product (containing 50 grams of carbohydrates)
Description: Fasted intake Second concept product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Second concept product (containing 50 grams of carbohydrates)
Description: Fasted intake Second concept product (randomised)
Study: NCT05242406

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Expiratory muscle trainig
Description: This exercise will be used to strengthen forced expiratory muscles.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Expiratory muscle trainig
Description: This exercise will be used to strengthen forced expiratory muscles.
Study: NCT05838352

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telerehabilitation exercise
Description: The telerehabilitation program is as follows; Respiratory exercises: Chest, diaphragmatic breathing and lower basal breathing exercises will be performed with 10 repetitions.Resistance exercises: Strengthening exercises will be performed on the major muscle groups of the upper and lower extremities, using medium-hardness resistance exercise band. During the exercises, the patient's fatigue and dyspnea levels will be questioned using the Borg scale, and breaks will be given when necessary. Exercises 1st-3rd weeks with 10 repetitions; 15 repetitions in weeks 4-6; In the 7th and 8th weeks, it will be done as 2 sets of 10 repetitions.Posture exercises: Basic posture exercises will be explained. Tabletop movements will be taught in clear, various positions that concern the spine, scapula and pelvis.Gait training: In line with the data obtained from the 6-minute walking test, gait training will be given on flat ground at 60% workload (land-based walking).
Study: NCT05676385

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Second concept product (containing 50 grams of carbohydrates)
Description: Fasted intake Second concept product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Reference product (containing 50 grams of carbohydrates)
Description: Fasted intake of Reference product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Reference product (containing 50 grams of carbohydrates)
Description: Fasted intake of Reference product (randomised)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Reference product (containing 50 grams of carbohydrates)
Description: Fasted intake of Reference product (randomised)
Study: NCT06084585

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Study Product A (High-dose 2X)
Description: participants in this arm will consume 1 sachet of this product with 200ml water per time, once a day after meal, for 3 months

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Study Product B (Low-dose X)
Description: participants in this arm will consume 1 sachet of this product with 200ml water per time, once a day after meal, for 3 months

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: participants in this arm will consume 1 sachet of this product with 200ml water per time, once a day after meal, for 3 months
Study: NCT04768647

Intervention type: DEVICE
Intervention: TNM
Description: TNM is a small portable head set that can be used by the participants at home to stimulate the vestibular system