TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05425368

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Silver diamine fluoride
Description: First permanent molars in this group will receive 38% silver diamine fluoride as an indirect pulp capping material.
Study: NCT06596187

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continuous passive motion device (CPM) of ankle - slow
Description: Continuous passive motion device (CPM) of ankle 0.25HZ (15rpm) for 10 repetitions

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continuous passive motion device (CPM) of ankle - slow
Description: Continuous passive motion device (CPM) of ankle 0.25HZ (15rpm) for 10 repetitions

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continuous passive motion device (CPM) of ankle - slow
Description: Continuous passive motion device (CPM) of ankle 0.25HZ (15rpm) for 10 repetitions
Study: NCT06587230

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Teachers Leading the Frontlines
Description: 1. During 3-day training, Knowledge and attitudes toward child mental health care are measured pre-training, post-training, and post-intervention.~2. The teachers select students whom they believe have the highest mental health needs to receive care.~3. Teachers analyze chosen students' symptoms.~4. Teachers analyze students' behavior with the AABC Chart.~5. Teachers develop a targeted response using a behavior plan called the 4Cs plan (Cause, Change, Connect, and Cultivate). In the 4Cs, teachers select therapeutic techniques to deliver from a menu of evidence-based therapeutic options for each category of behavior.~6. Throughout the year, teachers receive supervision through monthly site visits supplemented by as-needed telephone and digital discussions to guide their care from the study team. Teachers encourage the use of the 4Cs plan at home.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Responding to Students' Emotions Through Education
Description: All processes for RE-SEED are the same as in Tealeaf except...~1. Teachers receive only 1 day of training~2. The study team does not provide supervision to the teachers, allowing only the school counselor to provide supervision~This less resource-intensive approach will allow for an ethical comparator to Tealeaf, where the schools would like for teachers to have some skills to support identified students.
Study: NCT06601335

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK117 in combination with AK112
Description: Following a predefined dose and date.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo in combination with Pembrolizumab
Description: Following a predefined dose and date.
Study: NCT06501690

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Late bedtime
Description: Participants will go to bed 1 hour later than their habitual bedtime

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Variable bedtime
Description: Participants will go to bed at a prescribed time that varies each day within +/-1 hour of habitual bedtime
Study: NCT06674642

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Indigenous Foods diet
Description: A diet composed of traditional indigenous foods will be given to participants.
Study: NCT06266351

Intervention type: DEVICE
Intervention: This is observational IOP measurement
Description: IOP measurement of patients having LASIK with both CATS and GAT

Intervention type: DEVICE
Intervention: This is observational IOP measurement
Description: IOP measurement of patients having LASIK with both CATS and GAT
Study: NCT06543862

Intervention type: OTHER
Group type: OTHER
Intervention: CADx (AI) system
Description: The CADx system will be used to predict the histopathology of the polyp detected.
Study: NCT06673732

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Energy Technique with Stationary Bi-Cyclying
Description: MET for post-isometric relaxation of the Achilles, calf, quads, hamstrings, and ankle, position each muscle at resistance, just short of pain. The patient contracts (10-20% effort) for 5-10 seconds while the therapist resists. After relaxing and exhaling, the therapist gently stretches the muscle to the new barrier. Repeat this process 2-3 times, gradually increasing the stretch with each repetition.~For PFS MET of the Achilles tendon, calf, quads, hamstrings, and ankle, contract the muscle maximally for 5-10 seconds while the therapist resists. Afterward, the muscle is relaxed, and the therapist quickly stretches it to the new barrier, holding for 10 seconds. Following a 20-second rest, repeat the process 3-5 times. For Reciprocal Inhibition MET, the muscle is placed mid-range, the patient pushes against resistance, then relaxes while the therapist stretches the muscle. This is repeated 3-5 times. Stationary cycling complements the routine.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Energy Technique without Stationary Cycling
Description: MET for post-isometric relaxation of the Achilles, calf, quads, hamstrings, and ankle, position each muscle at resistance, just short of pain. The patient contracts (10-20% effort) for 5-10 seconds while the therapist resists. After relaxing and exhaling, the therapist gently stretches the muscle to the new barrier. Repeat this process 2-3 times, gradually increasing the stretch with each repetition. Post FS MET of the Achilles tendon, calf, quads, hamstrings, and ankle, contract the muscle maximally for 5-10 seconds while the therapist resists. Afterward, the muscle is relaxed, and the therapist quickly stretches it to the new barrier, holding for 10 seconds. Following a 20-second rest, repeat the process 3-5 times. For Reciprocal Inhibition MET, the muscle is placed mid-range, the patient pushes against resistance, then relaxes while the therapist stretches the muscle. This is repeated 3-5 times without Stationary Cycling
Study: NCT06675136

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tumor biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical Device Usage and Evaluation
Description: Given PIPAC
Study: NCT06680986

Intervention type: OTHER
Intervention: Clinical cardiac parameters (Arterial pressure, number of anti-hypertensive medications, and the NT-proBNP measurements)
Description: The degree of severity of the hypertension will have been previously diagnosed for each patient with the help of the blood pressure measurements, the number of antihypertensive treatments and the NT-proBNP measurement which is correlated with the left intraventricular pressure and the mass of the left ventricle. This information will be used (i) to guide the structuring of the pathology representation space during the learning phase from a sub-population (a portion of the collected database that will be used for training algorithms); (ii) to serve as an endpoint from a test sub-population (the remaining portion of the database collected).
Study: NCT06709625

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transversus thoracis plane block
Description: Transversus thoracis plane block will be applied to provide postoperative analgesia.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector spina plane block (ESP)
Description: Erector spina plane block will be applied to provide postoperative analgesia.
Study: NCT06708546

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dielac Grow Plus
Description: Dialac Grow Plus is an Oral Nutritional Supplementation made by Vietnam Dairy Products Joint Stock Company - Vinamilk.~Condition: Liquid~Color: White~Date of use: 8 months from the manufactured date.~Preserve: Store in a clean, dry place, and avoid direct sunlight.
Study: NCT06710821

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liposomal irinotecan in combination with vincristine and temozolomide
Description: Vincristine: 1.5 mg/m², iv, d1. l Temozolomide 150 mg/m²/d, iv drip, d1-5. l Irinotecan liposomal RP dose, iv infusion over 90 min, d1. Q3W, 4 cycles expected until disease progression or intolerable toxicity occurs
Study: NCT06707714

Intervention type: DIAGNOSTIC_TEST
Intervention: hypertension
Description: Gastric cancer patients with hypertension

Intervention type: DIAGNOSTIC_TEST
Intervention: diabetes
Description: diagnosed with diabetes

Intervention type: DIAGNOSTIC_TEST
Intervention: fatty liver
Description: diagnosed with fatty liver
Study: NCT06384690

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Micro-vegetable blend
Description: The intervention in this study is 6 weeks with a daily proprietary blend micro-vegetables that has been freeze-dried

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The intervention in this study is 6 weeks with a placebo supplement
Study: NCT04308603

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: NON-IMMUNE HYDROPS FETALIS diagnosis
Description: Amniotic liquid of each selected patients will be tested by both technic to describe and detect etiological information. Each patient will be tested using the current procedure with a defined panel of genes as well as with the NGS procedure. The results of both procedures will be compared.
Study: NCT05548738

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: medthylprednisolone
Description: a type of steroids injected in epidural space

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: prolotherapy
Description: a type of hypertonic glucose
Study: NCT05131360

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Introduction Only
Description: This is the placebo condition in which participants engage in one day of introductory mindfulness activities.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Purpose Only
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of purpose-based mindfulness techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Connection Only
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of connection-based mindfulness techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Connection and Purpose
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of connection and purpose-based mindfulness techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Awareness Only
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of awareness-based mindfulness techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Awareness and Purpose
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of awareness and purpose-based mindfulness techniques.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Awareness, Purpose, and Connection
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of awareness, connection, and purpose-based mindfulness techniques

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Awareness and Connection
Description: Participants engage in one day of introductory mindfulness activities followed up by 5 days of awareness and connection-based mindfulness techniques.
Study: NCT05792423

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GE ultrasound system with increased acoustic output settings
Description: We will perform liver stiffness measurements with standard settings and an increased acoustic output enhanced ultrasound system. Pre and post ultrasound LFTs will be collected to monitor unexpected liver tissue damage.
Study: NCT05030324

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XC221 100 mg
Description: Regardless of the group, all study subjects will receive the standard symptomatic therapy for influenza and other viral URIs, taking into account the latest clinical guidelines (the necessity of symptomatic therapy will be decided by the Investigator).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XC221 200 mg
Description: Regardless of the group, all study subjects will receive the standard symptomatic therapy for influenza and other viral URIs, taking into account the latest clinical guidelines (the necessity of symptomatic therapy will be decided by the Investigator).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Regardless of the group, all study subjects will receive the standard symptomatic therapy for influenza and other viral URIs, taking into account the latest clinical guidelines (the necessity of symptomatic therapy will be decided by the Investigator).
Study: NCT04918576

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: 3 grams of tranexamic acid (30mL of 100 mg/mL solution) diluted in 10 mL of normal saline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: 40 mL topical of 0.9% normal saline
Study: NCT06319638

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: During the treatment, All the participants were provided with the rehabilitation therapy, which included routine rehabilitation, cognitive training, swallowing function training and nutrition support.
Study: NCT05407194

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Collagen + vitamin C
Description: Participants take the supplement (or placebo) every day for 24 weeks. On three days per week they perform tendon loading exercises.
Study: NCT06319638

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Rehabilitation therapy
Description: During the treatment, All the participants were provided with the rehabilitation therapy, which included routine rehabilitation, cognitive training, swallowing function training and nutrition support.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: Based on the invention above, the patients in the observation group were provided with Stellate ganglion block, using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g). The percutaneous approach via the paratracheal route was used for Stellate ganglion block . The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo block
Description: 1 milliliter of normal saline will be used for injection. The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine Hydrochloride
Description: the patients in the observation group were provided with Stellate ganglion block, using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g). Once a day, totally 10 days.
Study: NCT05425368

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mineral trioxide aggregate
Description: First permanent molars in this group will receive mineral trioxide aggregate as an indirect pulp capping material.
Study: NCT05312073

Intervention type: OTHER
Group type: OTHER
Intervention: Biological samples
Description: Blood samples Superficial skin Biopsy Collection of fallen squames Tapes - stripping

Intervention type: OTHER
Group type: OTHER
Intervention: Skin biopsy
Description: healthy skin from surgery interventions
Study: NCT05760105

Intervention type: OTHER
Intervention: Patient Participation Form
Description: A form that consists of revised osteoporosis knowledge test, osteoporosis self-efficacy scale, and osteoporosis health belief scale.
Study: NCT04676399

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrochlorothiazide 12.5mg
Description: 2 pills/day (1 pill every morning and 1 pill every evening) for 14 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 pills/day (1 pill every morning and 1 pill every evening) for 14 days
Study: NCT06356207

Intervention type: DIAGNOSTIC_TEST
Intervention: Tilt Table Test
Description: The main goal of the study is to evaluate the time elapsed between the T-LOC during Video Tilt Table Testing and the asystole at the ECG using a national registry and to assess its predictive value in patients undergoing invasive treatment. The hypothesis is that a vasodepressive component could lessen the effect of pacing in a patient, leading to cerebral hypoperfusion and syncope despite maintaining a stable rhythm.
Study: NCT05468333

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cigarette trial
Description: Per NIH Program Official, this is not an ACT and thus full protocol info is not required at this time (and would be detrimental to the study if details were disclosed during recruitment).
Study: NCT05650333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ritlecitinib 20 mg
Description: orally administered, Ritlecitinib 20 mg once daily (QD)
Study: NCT04795089

Intervention type: PROCEDURE
Intervention: Shunt surgery
Description: Patients are evaluated before and after shunt surgery which is a standard intervention in the clinical practice. HI do not undergo intervention.
Study: NCT06067490

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC1416(SAD)
Description: RC1416(SAD),there are six doses(25mg-600mg) in this part. Each subjects will receive the drug once by subcutaneous injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo(SAD)
Description: Placebo(SAD), Each subjects will receive the placebo once by subcutaneous injection.
Study: NCT06640894

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MegaPower training
Description: See arm/group descriptions

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: See arm/group descriptions
Study: NCT05154799

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Proprioception and tactile localization with manual or ocular response and/or free hand grasp
Description: In the first part of the study, the subject must designate a target in 2 ways: manual pointing or ocular saccadic response.~In the second part of the study the subject will have to reach and grasp a rectangular block of wood placed on the table at a distance of 35 cm. He will have to catch the wooden block, lift it a few centimeters and put it back on the table. Tool use and control phases: the subject grasps the wooden block with a tool or without the tool but with a weighted bracelet loading his wrist by the same amount as the tool.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Proprioception and tactile localization with manual or ocular response and/or free hand grasp
Description: In the first part of the study, the subject must designate a target in 2 ways: manual pointing or ocular saccadic response.~In the second part of the study the subject will have to reach and grasp a rectangular block of wood placed on the table at a distance of 35 cm. He will have to catch the wooden block, lift it a few centimeters and put it back on the table. Tool use and control phases: the subject grasps the wooden block with a tool or without the tool but with a weighted bracelet loading his wrist by the same amount as the tool.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Proprioception and tactile localization with manual or ocular response and/or free hand grasp
Description: In the first part of the study, the subject must designate a target in 2 ways: manual pointing or ocular saccadic response.~In the second part of the study the subject will have to reach and grasp a rectangular block of wood placed on the table at a distance of 35 cm. He will have to catch the wooden block, lift it a few centimeters and put it back on the table. Tool use and control phases: the subject grasps the wooden block with a tool or without the tool but with a weighted bracelet loading his wrist by the same amount as the tool.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Proprioception and tactile localization with manual or ocular response and/or free hand grasp
Description: In the first part of the study, the subject must designate a target in 2 ways: manual pointing or ocular saccadic response.~In the second part of the study the subject will have to reach and grasp a rectangular block of wood placed on the table at a distance of 35 cm. He will have to catch the wooden block, lift it a few centimeters and put it back on the table. Tool use and control phases: the subject grasps the wooden block with a tool or without the tool but with a weighted bracelet loading his wrist by the same amount as the tool.
Study: NCT06641076

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sonelokimab
Description: Randomized treatment, parallel-group

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sonelokimab
Description: Randomized treatment, parallel-group

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Randomized treatment, parallel-group
Study: NCT05539131

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: transcranial direct current stimulation (tDCS)
Description: Transcranial direct current stimulation (tDCS) suppresses excitability and regulates excitability of neurons by injecting a small amount of current through electrodes attached to the scalp.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: transcranial direct current stimulation (tDCS)
Description: Transcranial direct current stimulation (tDCS) suppresses excitability and regulates excitability of neurons by injecting a small amount of current through electrodes attached to the scalp.
Study: NCT06525246

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-7475
Description: Specified dose, once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib Mesylate
Description: Specified dose, once daily