TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05543824

Intervention type: DRUG
Intervention: Levobupivacaine
Description: Patients who require placement of an epidural catheter to control postoperative pain and invasive blood pressure will be identified, allowing advanced monitoring using the MostCare Up® device. After identification, the objective of the study will be explained and their consent will be requested to collect the data after the intervention, recording the hemodynamic data before and after the initial bolus of local anesthetic administered: 0.25% levobupivacaine, the dose of which is calculated with the Takasaki formula: 0.05ml x weight (kg) x number of dermatomes to anesthetize
Study: NCT04988321

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prolonged continuous theta burst stimulation (pcTBS)
Description: Non-invasive brain stimulation (transcranial magnetic stimulation or TMS) which consists of a stimulating coil being held over the head. When this coil delivers a painless magnetic pulse, it feels like a quick, light tap on the head. Two different coils will be used to perform TMS. One coil will be used to determine stimulation parameters for the pcTBS protocol. The second coil will be used to implement pcTBS, which is a repetitive non-invasive brain stimulation protocol which feels like many quick, light taps on the head. Participants will receive two procedures during one session, one with active stimulation and one with inactive stimulation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prolonged continuous theta burst stimulation (pcTBS)
Description: Non-invasive brain stimulation (transcranial magnetic stimulation or TMS) which consists of a stimulating coil being held over the head. When this coil delivers a painless magnetic pulse, it feels like a quick, light tap on the head. Two different coils will be used to perform TMS. One coil will be used to determine stimulation parameters for the pcTBS protocol. The second coil will be used to implement pcTBS, which is a repetitive non-invasive brain stimulation protocol which feels like many quick, light taps on the head. Participants will receive two procedures during one session, one with active stimulation and one with inactive stimulation.
Study: NCT04770298

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Halliwick Concept
Description: Halliwick Concept: Water intervention Bobath Concept: Neurodevelopmental Treatment

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Halliwick Concept
Description: Halliwick Concept: Water intervention Bobath Concept: Neurodevelopmental Treatment
Study: NCT06033690

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: multidisciplinary guide
Description: use of the food guide for education, clarification of doubts
Study: NCT06297954

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metoclopramide
Description: Patients will receive metoclopramide 20 mg IV in a single dose prior to randomization.
Study: NCT05021172

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Receive usual care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Informational Intervention
Description: Receive Passport to Health booklet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Complete ePrognosis
Study: NCT06297954

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive placebo 10 ml IV in a single dose prior to randomization.
Study: NCT05021172

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies
Study: NCT04511936

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: i-Lumen AMD
Description: Microcurrent stimulator

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: i-Lumen AMD Sham
Description: Sham microcurrent stimulator
Study: NCT06153914

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sequential Adult Left Lateral Liver Transplantation
Description: Hemihepatectomy combined with orthotopic left lateral lobe liver transplantation is performed first, and residual liver resection is performed after the graft has grown to a sufficient functional liver volume. After the two-stage surgery, we will follow up on all subjects for one year.
Study: NCT05973279

Intervention type: OTHER
Intervention: Tecno Body Prokin Isokinetic Balance System
Description: It provides objectively measurable data in static and dynamic balance measurements. The moving balance platform of the system, which is driven by air piston servo motors, can measure at a working angle of 15 degrees in all directions. The results can be monitored and recorded live on the screen on the device. From these data, each individual's static and dynamic balance score is obtained by summing the forward-backward standard deviation and right-left standard deviation.
Study: NCT05417282

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MW151
Description: Females: 20 mg MW151 daily (10 mg capsule BID), for 28 days; Males: 10 mg MW151 daily (10 mg capsule QD), for 28 days.
Study: NCT05307068

Intervention type: OTHER
Intervention: No intervention was applied to the groups the samples will be collected in terms of the diagnosis ( periodontitis, healthy)
Description: No intervention was applied to the groups the samples will be collected in terms of the diagnosis (periodontitis, healthy)

Intervention type: OTHER
Intervention: No intervention was applied to the groups the samples will be collected in terms of the diagnosis ( periodontitis, healthy)
Description: No intervention was applied to the groups the samples will be collected in terms of the diagnosis (periodontitis, healthy)
Study: NCT04386252

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AV-COVID-19
Description: Autologous dendritic cells previously loaded ex vivo with SARS-CoV-2 spike protein

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AV-COVID-19
Description: Autologous dendritic cells previously loaded ex vivo with SARS-CoV-2 spike protein
Study: NCT05416593

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: General exercise prescription (FITT)
Description: The (1) control group (FITT) will receive a preexercise evaluation and 3 individualized training sessions based on the ACSM and FITT principles (ACSM, 2021). These are the procedures commonly used for apparently healthy individuals that start to exercise in health clubs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Affective regulation (AFFECT)
Description: As for the (2) experimental group (AFFECT), the focus will be given to exercise intensity assessment and manipulation. The same preexercise evaluation, number of individualized sessions, and methodological approach (i.e., FITT) will be made. However, individual preferences and experiences regarding exercise intensity will be assessed in the preexercise evaluation. These will be used to select the exercise sessions' initial intensity. Moreover, intensity self-selection guidance and affective response assessments will be made throughout the session for continuous intensity adjustments (aiming for pleasurable feelings).
Study: NCT05973279

Intervention type: OTHER
Intervention: Restorative Therapies RT300 leg/arm/cor:
Description: RT300 is a motorised treatment system. In general there are 3 systems; Passive therapy, Active therapy and a combination of active therapy with some assistance from the motor. The device can be used from a chair, wheelchair or bed and there are two variants that can be used separately; Leg system, Arm system. Electrodes placed on the skin over specific muscle groups are connected via a cable or wirelessly to the RT300. These are used to stimulate peripheral motor nerves, causing the muscles to work. The software of the SAGE controller unit of the RT300 monitors the treatment process, including the stimulation patterns sent to the arms or legs, and the operation of the ergometer motor to produce smooth cycling motion. Contraindicated in the presence of lower limb fractures or pregnancy.

Intervention type: OTHER
Intervention: CSMI (CYBEX) Humac Norm Isokinetic Test and Exercise System
Description: 22 isolated joint movement models, 4 resistance modes (isokinetic, isotonic, isometric and passive) and a large number of reports to meet the measurement and exercise needs of today's clinicians and researchers. The exercise modes of the device include; Continuous passive movement, multi-angle isometry, proprioception training, standard and eccentric focused isokinetic strengthening, deceleration training, dynamic isotonic training, strength training. Test modes of the device include; Proprioceptive, co-measured, standard isokinetic, concentric/eccentric isokinetic, intermittent stroke isokinetic test.
Study: NCT04523701

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: white test (= the administration of SMOFlipid retrograde through the cystic duct)
Description: white test (= the administration of SMOFlipid retrograde through the cystic duct)
Study: NCT06102616

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: measure Osteocalcin level
Description: in gingival crevicular fluid before and during orthodontic tooth movement
Study: NCT05166070

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RD133
Description: The enhanced MSLN-CAR-T cell design of this study is obtained by co-infecting T cells with two lentiviral vectors. One lentiviral vector expresses CD19-CAR and tEGFR molecular safety switch, and the other lentiviral vector expresses MSLN- CAR and dnTGFβRII receptors. dnTGFβRII receptor without intracellular signal is used to resist the inhibition of T cell function by the immune microenvironment of tumor tissue. In addition, for the safety of CAR-T cell application in vivo, tEGFR is used in the CAR design as a molecular safety switch for CAR-T cells.
Study: NCT06499766

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Biodiversity intervention by inactivated microbial extract
Description: Participants use the lotion including microbial extract on one arm twice a day for 28 days. No other lotions or creams are used simultaneously on this area. Atopy medicines are not used during the trial or 14 days before the trial.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo intervention by colored lotion
Description: Participants use the lotion including safe, non-active coloring ingredient on one arm twice a day for 28 days. No other lotions or creams are used simultaneously on this area. Atopy medicines are not used during the trial or 14 days before the trial.
Study: NCT06234956

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BIMERVAX
Description: BIMERVAX
Study: NCT06521541

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimodal prehabilitation program
Description: Patients adopted planned, structural, repetitive and purposeful approach that includes elements of exercise, nutritional and psychological.Patients were evaluated for changes during neoadjuvant therapy and postoperative recovery

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ERAS program
Description: The core content is to adopt a series of optimized measures performed during the perioperative period on the basis of evidence-based medical findings to reduce the physiological and psychological stress of patients and to accelerate their recovery.
Study: NCT05606484

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise with non-immersive virtual reality
Description: Patients will exercise for 30 minutes with non-immersive virtual reality (VR) with a perceived exertion between 12-15 (somewhat hard-hard) on the Borg scale. Patients will perform 3 weekly sessions during the second hour of hemodialysis, on simultaneous days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise with non-immersive virtual reality
Description: Patients will exercise for 30 minutes with non-immersive virtual reality (VR) with a perceived exertion between 12-15 (somewhat hard-hard) on the Borg scale. Patients will perform 3 weekly sessions during the second hour of hemodialysis, on simultaneous days.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise with a static pedal
Description: Patients will exercise with a stationary pedal for 30 minutes at an intensity of 12-15 (somewhat hard-hard) on the Borg scale of perceived exertion. The patients will carry out an exercise session 3 times a week on alternate days, coinciding with the patients of the exercise with VR.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise with a static pedal
Description: Patients will exercise with a stationary pedal for 30 minutes at an intensity of 12-15 (somewhat hard-hard) on the Borg scale of perceived exertion. The patients will carry out an exercise session 3 times a week on alternate days, coinciding with the patients of the exercise with VR.
Study: NCT05048758

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05298813

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBIO123
Description: IBIO123 1 mg, 5 mg and 10 mg

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo
Study: NCT04185636

Intervention type: DEVICE
Intervention: MolecuLight i:X imaging
Description: The MolecuLight i:X Imaging Device will be used to take standard (ST) and fluorescent (FL) images of each graft site. The MolecuLight i:X will also be used to take measurements of the wound using the measurement feature of the device.
Study: NCT06404723

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibrinogen to albumin Ratio and C-reactive to Albumin Ratio
Description: to detect their relation to disease activity to use as predective and prognostic tools

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibrinogen to albumin Ratio and C-reactive to Albumin Ratio
Description: to detect their relation to disease activity to use as predective and prognostic tools

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibrinogen to albumin Ratio and C-reactive to Albumin Ratio
Description: to detect their relation to disease activity to use as predective and prognostic tools
Study: NCT05829395

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: metaverse- based education
Description: The nursing process course will be conducted in a metaverse environment. A virtual classroom is designed in the metaverse space for the execution of this course.~Starting from the week following the pre-test application, online training will continue according to the Metaverse-based for a total of 3 weeks, two hours a week, for the intervention group. At the end of the 3 weeks, the Instructional Materials Motivation Scale and Academic Success Assessment (Quiz) will be re-administered as a post-test.
Study: NCT05693103

Intervention type: DEVICE
Intervention: High-Intensity Focused Electromagnetic therapy
Description: The HPM-6000UF is a non-invasive therapeutic device. The device produces electromagnetic field that interacts with the tissues of the human body.~The electromagnetic field delivered in the muscular or neuronal tissue area is triggering the stimulation and tonisation.
Study: NCT05730127

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conditioning stimulus
Description: Pain stimulus on non-dominant side

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conditioning stimulus
Description: Pain stimulus on non-dominant side

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conditioning stimulus
Description: Pain stimulus on non-dominant side
Study: NCT04708769

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone App Participants (APP)
Description: Participants will receive calorie, fat, and physical activity goals, a Smartphone application for self-monitoring their diet, activity and weight, online educational readings, and brief bi-weekly remote health sessions with a Health Promotionist. They will also be provided with a wireless bluetooth scale and portable blood pressure machine.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Prevention Program Participants (DPP)
Description: In accordance with the Center for Disease Control curriculum, participants will receive a participant log for tracking physical activity, food intake, and weight, a paper participant guide with worksheets, logs, and psycho-educational materials, and 16 hour long remote sessions with a Health Promotionist. They will also be provided with a wireless bluetooth scale and portable blood pressure machine.
Study: NCT04773847

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical reconstruction of maxillofacial osseous defect with MimetikOss 3D.
Description: Surgical reconstruction of maxillofacial osseous defect with MimetikOss 3D.
Study: NCT04885127

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Palliative Care + Digital Symptom Monitoring
Description: Previously described in Arm description
Study: NCT04851743

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry needling
Description: The experimental extremity will received a single treatment session of TrP dry needling as follows: the therapist will located the TrP and will applied manual compression until the participant will reported pain. After that, dry needling technique will be performed on the TrPs for 60 seconds.
Study: NCT05838469

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pediatric Strip Crown and High Viscosity Glass Ionomer Cement
Description: Following the decision on the appropriate size of celluloid strip crown, the tooth will be isolated using roll cottons and the cavity conditioner (GC, Japan) will be applied to all surfaces for 10 seconds, washed away and dried with cotton pellets. The selected celluloid strip crown will be filled with a fluoride-releasing bulk fill hybrid glass ionomer cement (EQUIA Forte, GC, Japan) prepared by mixing for 10 seconds in an automatic mixer and placed on the tooth with light pressure. The excess material on the crown margins will be removed with a hand instrument, and the celluloid strip crown will be removed from the tooth. If necessary, the restoration will be polished using a polishing discs. After the crown surface is washed and dried, a nano-filled surface sealant (EQUIA Forte Coat, GC, Tokyo, Japan) will be applied for 10 seconds with a micro-tipped applicator and light cured for 20 seconds.
Study: NCT04948060

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enhanced lung cancer screening services
Description: A theoretically sound and evidence-based, multi-component implementation strategy will be applied which includes care quality benchmarking and regular performance feedback, academic detailing provided by specially trained primary care clinicians, practice facilitation provided by trained and certified Practice Facilitators (PFs), health information technology (HIT) support, and facilitated professional networking to promote the cross-pollination and rapid dissemination of solutions and best practices in primary care settings
Study: NCT06046794

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Analyze of GemCore status
Description: Genomic analyze of GemCore status
Study: NCT05806918

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human Interferon α-2b Gel (After the Alteration)
Description: Recombinant human interferon α-2b gel (after the alteration of the active ingredient manufacturer) will be applied to the lesions as a thin layer, at the frequency of four times a day, together with the therapy of valaciclovir hydrochloride.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Recombinant Human Interferon α-2b Gel (Before the Alteration)
Description: Recombinant human interferon α-2b gel (before the alteration of the active ingredient manufacturer) will be applied to the lesions as a thin layer, at the frequency of four times a day, together with the therapy of valaciclovir hydrochloride.
Study: NCT05225376

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical activity sessions for pregnant women
Description: The physical activity sessions will take place once a week at the Estaing UHC, in the room used for the childbirth and parenting preparation classes of the outpatient obstetrics-gynecology clinic; and twice a week on Zoom. These sessions will be supervised by an APA professional (degree in STAPS and APA).~The measurement of the women's physical conditions will make it possible to adapt and individualize the PA sessions to each woman's level.
Study: NCT06262204

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hallux Valgus Treatment with Shark Screw®
Description: This is a prospective, randomised study in which hallux valgus is corrected by means of a chevron/kin surgery technique using metal screws or human allogenic cortical bone screws (Shark Screw®, Surgebright, Lichtenberg, Austria). X-rays are taken before the operation at 6 weeks, three, six and twelve months after the operation. The X-ray images provide information on whether bony degeneration has taken place. In addition, the American Orthopaedic Foot \& Ankle Society (AOFAS) hallux score, FFI score, hallux valgus angle (HVA) and intermetatarsal angle (IMA) are determined. These data are collected preoperatively and 4 weeks (HVA and IMA), six and twelve months postoperatively in order to rule out a change in the HVA and IMA and to document the changes in the AOFAS/FFI.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Hallux Valgus Treatment with metal screw
Description: This is a prospective, randomised study in which hallux valgus is corrected by means of a chevron/kin surgery technique using metal screws or human allogenic cortical bone screws (Shark Screw®, Surgebright, Lichtenberg, Austria). X-rays are taken before the operation at 6 weeks, three, six and twelve months after the operation. The X-ray images provide information on whether bony degeneration has taken place. In addition, the American Orthopaedic Foot \& Ankle Society (AOFAS) hallux score, FFI score, hallux valgus angle (HVA) and intermetatarsal angle (IMA) are determined. These data are collected preoperatively and 4 weeks (HVA and IMA), six and twelve months postoperatively in order to rule out a change in the HVA and IMA and to document the changes in the AOFAS/FFI.