TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04535375

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Doppler Ultrasound of venous cerebral circulation
Description: No additional ultrasound examinations, specifically for the purpose of this study, will be performed. Instead, with each routine ultrasound examination, additional images on top of the routine frames will be collected. Those images will document the velocity and flow in the internal cerebral veins bilaterally using the standard Color Doppler tech-nique. Taking these additional images will prolong the time of ultrasound examination only minimally (with a few minutes).
Study: NCT05649137

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive once-weekly s.c. injection of placebo matched to semaglutide for 72 weeks. Injections may be administered in the thigh, abdomen, or upper arm, at any time of day irrespective of meals.
Study: NCT06551987

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy for Insomnia
Description: 6 weekly, 50-minute sessions delivered individually using in-person or telehealth format by a trained behavioral health provider.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brief Behavioral Therapy for Insomnia
Description: 4 weekly, 30-minute sessions delivered individually using in-person or telehealth format by a trained behavioral health provider.
Study: NCT06294535

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: reconstruction of orbital walls
Description: under GA, incision to access to orbital walls. Then insertion of prebent titanium mesh or customized titanium implant and fixation with miniscrews, examination of ocular motility using forced duction test followed by closure of flap.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: reconstruction of orbital walls
Description: under GA, incision to access to orbital walls. Then insertion of prebent titanium mesh or customized titanium implant and fixation with miniscrews, examination of ocular motility using forced duction test followed by closure of flap.
Study: NCT05384275

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Flow Nasal Therapy
Description: High Flow Nasal Oxygen (Airvo2 Device)
Study: NCT04850313

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ProProKera Plus®
Description: ProKera® is a sutureless form of CryoTek amniotic membrane that is clipped into a dual polycarbonate ring system with the epithelial side up when in contact with the ocular surface.
Study: NCT06227455

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary alveolar ridge augmentation
Description: The surgical procedure involves careful flap reflection, autogenous graft harvesting, and placement and fixation of the barriers over mixture of Autogenous graft and xenograft particles.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Maxillary alveolar ridge augmentation
Description: The surgical procedure involves careful flap reflection, autogenous graft harvesting, and placement and fixation of the barriers over mixture of Autogenous graft and xenograft particles.
Study: NCT06201416

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SBT777101
Description: Experimental treatment

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SBT777101
Description: Experimental treatment

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SBT777101
Description: Experimental treatment
Study: NCT05294913

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contextualized Wish-Outcome-Obstacle-Plan (WOOP) intervention
Description: This intervention will ask students to identify socio-culturally integrated academic or personal goals, so that students may be able to better strategize obstacle-overcoming to attain their future academic aspirations and modulate negative emotions or environments and associated physiological responses.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo control group will receive a 5- to 10-minute online goal-setting video tutorial and confirm that they have completed it by filling out an online check-list.
Study: NCT05625269

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: The first session of the individual training will be held for the patients in the intervention group on the first day of the service hospitalization, covering the issues related to the procedure and the hospital process. Afterwards, the second session of individual education will be held the day before discharge on issues related to the patient's home care, such as treatment site care, nutrition, exercise, medication and symptom management. In addition to the patients, their families will also participate in the training sessions. The training will be given face-to-face in a quiet environment to increase intelligibility in patients' rooms. The patients will be given a booklet and magnet prepared by the researcher in addition to the oral explanation.
Study: NCT05384587

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: asciminib
Description: Supplied in 40 mg and 100 mg tablets for oral use to be taken daily. Dose may be increased at 6 and 12 months based on molecular response with BCR-ABL1 Polymerase Chain Reaction testing.
Study: NCT05397808

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates Training
Description: The group that received pilates training.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: breathing and relaxation exercises
Description: The group who received breathing and relaxation exercises with a home program.
Study: NCT05910931

Intervention type: DRUG
Intervention: ICG angiography
Description: * A first injection with the patient asleep before starting the intervention to visualize the vascular anatomy of each patient and assess the pedicles and incisions.~* A second bolus after breast resection to assess the viability of skin flaps and glandular pedicles.~* A third injection to obtain an angiography after implant placement and wound closure.~For angiography, the SPY System with the SPY-Q software will be used.
Study: NCT05051397

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HYPERCAPNIA
Description: Controlled moderate hypercapnia PaCO2 50mmHg under general anesthesia with mechanical ventilation
Study: NCT06390982

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: 130 mg/m2 IV on Day 1 of each 21-day cycle in CAPOX regimen
Study: NCT05051397

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: NORMOCAPNIA
Description: Controlled normocapnia PaCO2 40mmHg under general anesthesia with mechanical ventilation
Study: NCT05013190

Intervention type: OTHER
Intervention: No intervention
Description: This is a non-interventional study.
Study: NCT06610370

Intervention type: OTHER
Intervention: Group 1
Description: 95 children with spastic cerebral palsy were included. Gross Motor Function Measure-88 (GMFM-88) and Gross Motor Function Classification System (GMFCS) were applied to the cases before and after the Selective Dorsal Rhizotomy (SDR) surgery.
Study: NCT04428164

Intervention type: OTHER
Intervention: The Richards-Campbell Sleep Questionnaire (R-CSQ)
Description: Tool developed to assess patient satisfaction and comfort in the hospital setting.~The R-CSQ is a scale used to measure different aspects of sleep quality. This scale allows the patient to rate their quality and amount of sleep on a scale of 0-100. The R-CSQ allows the patient to rate six different components of their sleep, including sleep depth, sleep latency, awakenings, returning to sleep, sleep quality, and noise.

Intervention type: OTHER
Intervention: Revised American Pain Society Outcome Questionnaire (APS-POQ-R)
Description: The APS-POQ-R can be utilized to measure perceived levels of pain in patients. The APS-POQ-R scale is a validated scale that is used in the hospital setting with reliable and consistent results. This scale measures five aspects of a patient's perception and experiences with pain and a sixth aspect including nonpharmacological interventions.
Study: NCT06615583

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical device
Description: The C-REX device consists of an invasive surgical part, including two anastomotic rings, and surgical instruments for assisting the placement of the anastomotic ring to intestine. The rings are loosen from the inside of the intestinal wall and expelled with faeces per rectum once the anastomosis is healed in approximately ten days.
Study: NCT06615180

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Transcultural Nursing Course (new curriculum)
Description: Multinational Collaboration: Developed with input from institutions across five countries, ensuring a broad, international perspective on transcultural nursing.~Comprehensive Theoretical Framework: Integrates multiple cultural competence models (Purnell, Campinha-Bacote, Papadopoulos) with Leininger's Culture Care Theory, offering a thorough approach.~Extensive Practical Training: Includes 17 hours of hands-on experience, featuring hospital visits and interactions with healthcare professionals.~Interactive Learning Methods: Combines role-playing, reflective essays, and cultural activities (e.g., traditional clothing, dances) for dynamic, multimodal education.~Peer Education: Incorporates peer education and evaluation, enhancing collaborative learning and critical thinking.~Standardized Materials: Educational materials and teaching methods are standardized across institutions to ensure consistency and quality in instruction.
Study: NCT06615466

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Partial Breast Irradiation
Description: 26Gy/5.2Gy/5f
Study: NCT06613594

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Patients will receive hot pack, Broom stick ROM exercises, Codman and strengthening exercises. A total of 10 sessions, 5 sessions per week for 2 consecutive weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physical therapy
Description: Patients will receive hot pack, Broom stick ROM exercises, Codman and strengthening exercises. A total of 10 sessions, 5 sessions per week for 2 consecutive weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physical therapy
Description: Patients will receive hot pack, Broom stick ROM exercises, Codman and strengthening exercises. A total of 10 sessions, 5 sessions per week for 2 consecutive weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kaltenborn traction mobilization
Description: kaltenborn direction non specific traction mobilization for (1 minute), 3 sets of 10 reps with 1 minute rest in between will be given.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kaltenborn translatoric glides
Description: Kaltenborn direction specific linear tranlatoric glides, rhtymic 5reps of each glide, such anterior glide for extension and external rotation, caudal glide for abduction,post glide for flexion and internal roation,these3 sets of painless glides will performed with 10 reps,rest of 1 minutes between these sets.
Study: NCT06282770

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Laser Diode Brace
Description: The device is a brace with laser diodes. The braces light up and the red light has therapeutic abilities.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Laser Diode Brace
Description: The Sham brace has no therapeutic ability and will act as a placebo.
Study: NCT06493279

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RJK002 Intrathecal injection
Description: Eligible subjects will receive a single intrathecal administration of investigational product with dose 6E13 vg/person, 1.2E14 vg/person, and 2.4E14 vg/person sequentially.
Study: NCT05737563

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 Inhibitors
Description: Teripulimab 240mg, injection or Carrelizumab 200mg, injection, every 3 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Irinotecan
Description: Irinotecan: 200mg/m2, injection (For patients who are confirmed to be homozygous for UGT1A1\*6 or UGT1A1\*28 or UGT1A1\*6 and UGT1A1\*28 at the same time, the starting dose of CPT-11 is 150 mg/m2).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Irinotecan: 200mg/m2, injection (For patients who are confirmed to be homozygous for UGT1A1\*6 or UGT1A1\*28 or UGT1A1\*6 and UGT1A1\*28 at the same time, the starting dose of CPT-11 is 150 mg/m2).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine tablets
Description: Capecitabine: 1600 mg/m2/d, oral, 2 weeks on and 1 week off.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine tablets
Description: Capecitabine: 1600 mg/m2/d, oral, 2 weeks on and 1 week off.
Study: NCT05613010

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mHealth Messaging Intervention Group
Description: Participants will receive an electronic pill box; the research team will instruct participants on how to use this device. Participants will be asked to use the electronic pill box for their prescribed medicines for the duration of the study (up to 16 months). During the 12-week micro-randomized trial, participants will be randomized within person to receive (1) adherence support text messages or (2) no text message after each missed dose, and (1) praise text message or (2) no text message after each on time dose. Dose timing will be determined based on participant report of when they typically take their tacrolimus or sirolimus medicine.
Study: NCT06376994

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Air cleaner
Description: The intervention is two active air cleaners with high efficiency particulate air (HEPA) filters which remove PM, as well as activated carbon filters to remove NO2 (and other trace gases). These will be run for a year in a participant's house.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham air cleaner
Description: The sham intervention is two sham air cleaners that have the internal HEPA and carbon filters removed, but which will run normally, including similar noise, airflow, and overall appearance compared to active air cleaners, thus blinding participants to filter status. These will be run for a year in a participant's house.
Study: NCT06532279

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Best Practice
Description: Receive usual symptom management

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Practice
Description: Receive usual symptom management

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo collection of blood, serum, and/or plasma samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood, serum, and/or plasma samples

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cisplatin
Description: Given cisplatin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Given cisplatin

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Image Guided Radiation Therapy
Description: Undergo image-guided radiation therapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Image Guided Radiation Therapy
Description: Undergo image-guided radiation therapy

Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Intensity-Modulated Radiation Therapy
Description: Undergo intensity-modulated radiation therapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity-Modulated Radiation Therapy
Description: Undergo intensity-modulated radiation therapy

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT06390982

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 825 mg/m2 orally twice daily (bid) 5 days/week during radiotherapy.
Study: NCT06233032

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ephedrine
Description: Patient Will receive 6mg IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Patient Will receive 30mcg IV
Study: NCT06554626

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Glucocorticoids

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Blinatumomab
Description: Bi-specific anti CD19/CD3 antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: BCL-2 inhibotor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inotuzumab ozogamicin
Description: a humanized monoclonal antibody-drug conjugate targeting CD22

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: antifolate antineoplastic drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegaspargase
Description: antitumor drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Pyrimidine, antimetabolites
Study: NCT06156540

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality glasses
Description: Using virtual reality glasses, caregivers in the experimental group were shown 360-degree VR relaxing videos.
Study: NCT04824183

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music intervention
Description: Three WhatsApp sessions will be delivered before the surgery. In the first session, participants will describe their experience with the diagnosis of breast cancer and acceptance. In the second session, participants will be educated on anxiety before their surgery, how anxiety is being managed in the hospital and self-care strategies for anxiety like MI, how to report preoperative anxiety. The third session will include postoperative pain education. The pain education will include information about the type of pain to expect after surgery, medications, pain reporting and MI for pain management. Telephone session; on the day of surgery and at 24 and 48 hours after surgery, a reminder will be sent to the participants by WhatsApp group chat. Face-to-face; MI delivery will involve the delivery of the MP3 to participants and monitoring of their use for 30 minutes both on the day of surgery and 24 and 48 hours after surgery.
Study: NCT05503316

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamic balance training
Description: Participants will receive dynamic balance training while walking on the GRAIL device.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional gait rehabilitation
Description: Participants will receive traditional gait rehabilitation that also includes balance training while walking but not on the GRAIL device.
Study: NCT05607303

Intervention type: OTHER
Intervention: Clinical estrogen therapy
Description: No research interventions will be used as a part of the study since the research is observational. Estrogen treatment will be prescribed and followed by participant's clinical physician.
Study: NCT05686720

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SZ011 CAR-NK
Description: In the escalation study, the minimum initial dose was 5.0×10\^6 cells, then increased to 5.0×10\^7 and 2.0×10\^8 cells. The infusion is given every 2 weeks.
Study: NCT06532279

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MnSOD Mimetic BMX-001
Description: Given SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Administration
Description: Given SC
Study: NCT03328455

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Inhibitory control training
Description: Cognitive training is inhibitory task-related.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Knowledge-based training
Description: Training is not inhibitory task-related.
Study: NCT06532279

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05820789

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Family support
Description: Before the extubation procedure, the patient's relatives will be informed, and the patient will be allowed to enter the intensive care unit, and the patient will be able to express that he is with the patient by holding his hand and talking.
Study: NCT05926245

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Glutaryl Solution
Description: Glutathione, ascorbic acid, cyclodextrin, potassium sorbate and radish root extracts
Study: NCT06207851

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcatheter Arterial Micro-Embolization
Description: Participants will undergo TAME with Nexsphere-F.
Study: NCT05926245

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Solution
Description: Empty nanoparticles
Study: NCT05317689

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocin
Description: 17.5mg oral psilocin with psychological support and physiological monitoring

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: 25mg oral psilocybin with psychological support and physiological monitoring

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sublingual Psilocin
Description: 2.18mg - 4.36mg sublingual psilocin with psychological support and physiological monitoring

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sublingual Psilocin
Description: 2.18mg - 4.36mg sublingual psilocin with psychological support and physiological monitoring
Study: NCT06325904

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Uniportal VATS
Description: * single port video-assisted thoracoscopic surgery in the 5th intercostal space~* performed under general anesthesia.~* pleural fluid/pus was drained~* pleural adhesions was removed

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Tube thoracostomy
Description: * Chest tube is inserted in 5th mid-axillary line~* performed under local anaesthesia
Study: NCT05217927

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimegepant 75mg daily dosing
Description: Daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimegepant 75mg every other day dosing
Description: Every other day

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo comparator dosing
Description: Placebo comparator
Study: NCT06449378

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transorb™ Self-Gripping Resorbable Mesh
Description: Self-Gripping Resorbable Mesh used for repair of open ventral hernia.