TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05908435

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dispensers, Flyers, Enhanced Signage + a social media component delivered by teen ambassadors
Description: The study intervention is designed to increase utilization of free sunscreen dispensers, applying and reapplying sunscreen, and motivating use of other forms of sun protection by teens. IMPACT Melanoma will install and maintain free sunscreen dispensers at the study sites. Flyers will be posted at locations at the park/beach to inform people of the availability of free sunscreen and the location of the dispenser. 'Teen enhanced' signage will be present on the dispenser in the intervention parks/beaches. Teen ambassadors will share 3-5 posts to their social media platform over the course of 1 week encouraging sun protection practices and use of the free sunscreen dispenser (when the intervention is occurring at the study site).
Study: NCT04994912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EI-001
Description: EI-001 IV infusion

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo IV infusion
Study: NCT06410495

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NiteCAPP SINCC
Description: Standard CBT-I techniques along with modules targeting noncompliance in children with ODD and their parents.
Study: NCT06197503

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conduction system pacing
Description: Left bundle branch pacing or His bundle branch pacing

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Right ventricular pacing
Description: Conventional pacing
Study: NCT05137847

Intervention type: DRUG
Intervention: Remitoro
Description: Intravenous infusion.
Study: NCT05222022

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Retitrack
Description: Retitrack device measures and analyzes eye movement
Study: NCT05923866

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-2808
Description: Oral administration of ONO-2808 at low, middle or high doses once a daily for 24 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral administration of placebo once a daily for 24 weeks
Study: NCT04905732

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NHFOV
Description: After documenting parental consent, the ventilated infants with BPD were randomly assigned to NHFOV

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NCPAP
Description: After documenting parental consent, the ventilated infants with BPD were randomly assigned to NCPAP
Study: NCT04775342

Intervention type: DEVICE
Intervention: smartphone
Description: modern technology
Study: NCT05519137

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active lighting intervention
Description: Lighting intervention designed to impact the circadian system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active lighting intervention
Description: Lighting intervention designed to impact the circadian system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control lighting intervention
Description: Lighting intervention designed to have no impact on the circadian system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control lighting intervention
Description: Lighting intervention designed to have no impact on the circadian system
Study: NCT05397171

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD8853
Description: Monotherapy given until progressive disease or upon meeting other discontinuation criteria.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zirconium-89 crefmirlimab berdoxam
Description: CD8+ T cell tracer for positron emission tomography (PET) at two time points in addition to monotherapy AZD8853
Study: NCT06028958

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neck Isometrics Exercises
Description: Isometric exercises are tightening (contractions) of a specific muscle or group of muscles. During isometric exercises, the muscle doesn't noticeably change length. The affected joint also doesn't move. Isometric exercises help maintain strength.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Global Posture Re-Education
Description: Global postural rehabilitation (GPR) is an approach that considers the body in its overall aspect. This technique aims to relax the envelope of the muscles (fascia) while relaxing the muscle chains to reduce the strain on the joints. The end result is a more suitable posture and less pain.
Study: NCT05542407

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: 10 mg/kg- 20 mg/kg Atezolizumab will be administered by intravenous, on day 1 of each 21-day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: 10 mg/kg- 20 mg/kg Atezolizumab will be administered by intravenous, on day 1 of each 21-day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONC201
Description: 375 mg once weekly - 625 mg ONC201 will be administered orally, once or twice weekly.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONC201
Description: 375 mg once weekly - 625 mg ONC201 will be administered orally, once or twice weekly.
Study: NCT05022602

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Imagio
Description: Imagio - both ultrasound probe and Duplex OA probe
Study: NCT04908215

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INM-755 (cannabinol) cream
Description: topical cream containing cannabinol for dermal application

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: topical cream base for dermal application containing no active agent
Study: NCT05292417

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: hypofractionation Radiotherapy
Description: Patients will receive radiation to the target lesion at a dose of 5Gy, 5 fractions a week, or a dose of 8Gy, 3 fractions a week. The course last once or twice depending on the investigator.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sintilimab
Description: 200 mg per IV infusion every 21 days until disease progression or participant withdrawal from study or last for two years

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GM-CSF
Description: 200µg given 7-14 days(until WBC≥40x109/L), every 21 days until disease progression or participant withdrawal from study or last for two years.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquintinib will be given 5mg qd for 2 weeks on and 1 week off, Q3W.
Study: NCT05169112

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lupron Depot
Description: Patients randomized to receive androgen deprivation therapy (ADT) will receive 12 months of Lupron Depot (22.5 mg) administered every 3 months
Study: NCT05221268

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Level walking exercise
Description: treadmill exercise with 0 inclination

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Downhill exercise
Description: treadmill exercise with -20 inclination
Study: NCT06376136

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT8010 for Injection
Description: Intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT8010 for Injection
Description: Intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT8010 for Injection
Description: Intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT1006 for Injection
Description: Intravenous
Study: NCT06265701

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Derailment-Focused Reflective Journaling
Description: Experimental group aimed at decreasing anxiety symptoms

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Everyday Tasks Reflective Journaling
Description: Control group
Study: NCT04442451

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Exercise
Description: Each participant will attend 3 sessions per week for 8 weeks. Participants will perform low-load knee extension resistance training (20% of 1-RM) without blood flow restriction on the designated leg for 4 sets of contractions with 15 contractions per set of contractions with a 30 second rest between each set of contractions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood Flow Restriction Exercise
Description: Each participant will attend 3 sessions per week for 8 weeks. Participants will perform low-load knee extension resistance training (20% of 1-RM) with blood flow restriction on the designated leg for 4 sets of contractions with 15 contractions per set of contractions with a 30 second rest between each set of contractions.
Study: NCT05835362

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Question prompt list
Description: A question prompt list is a list of questions about ADHD (one page) given to study participants to select questions they may want to ask the provider. The youth question prompt list contains 22 questions, and the parent question prompt list contains 20 questions. Both are below a fourth-grade reading level.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Question prompt list
Description: A question prompt list is a list of questions about ADHD (one page) given to study participants to select questions they may want to ask the provider. The youth question prompt list contains 22 questions, and the parent question prompt list contains 20 questions. Both are below a fourth-grade reading level.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pre-visit video
Description: The 11-minute video has six themes: (a) talking to your doctor about ADHD, (b) controlling ADHD without medicine, (c) ADHD medications, (d) ADHD and school, (e) ADHD and your relationships, and (f) helping your parents understand your ADHD.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pre-visit video
Description: The 11-minute video has six themes: (a) talking to your doctor about ADHD, (b) controlling ADHD without medicine, (c) ADHD medications, (d) ADHD and school, (e) ADHD and your relationships, and (f) helping your parents understand your ADHD.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Combined question prompt list/video
Description: A question prompt list is a list of questions about ADHD (one page) given to study participants to select questions they may want to ask the provider. The youth question prompt list contains 22 questions, and the parent question prompt list contains 20 questions. Both are below a fourth-grade reading level.~And the video is an 11-minute video that has six themes: (a) talking to your doctor about ADHD, (b) controlling ADHD without medicine, (c) ADHD medications, (d) ADHD and school, (e) ADHD and your relationships, and (f) helping your parents understand your ADHD.
Study: NCT05718427

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ayres Sensory Integration Therapy
Description: Ayres sensory integration theory provides evidence from basic and applied science about the ability to receive, sort, process, and make use of the information originating from the body and the environment and perceived by our senses (touch, gravity, body position and movement, sight, smell, hearing, taste). This sensory information goes to the brain, where it is organized and interpreted. As a result, we form a plan of action that allows us to have an adaptive response appropriate for the demands of the environment. A thorough assessment guides the preparation of goals addressing the referring concerns and the recommendations for intervention. Ayres Sensory Integration intervention is provided within the context of professional practice. It is designed to improve sensory perceptual abilities, self-regulation, motor skills, and praxis. In doing so, it supports the client's ability to show improved behavior, learning, and social participation.
Study: NCT06579937

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine hydrochloride
Description: During anesthesia induction, a 0.2 mg/kg esketamine bolus was administered intravenously.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: During anesthesia induction, a bolus of equal 0.9% saline was administered intravenously.
Study: NCT05070429

Intervention type: OTHER
Group type: OTHER
Intervention: Clinic-based audiological rehabilitative service delivery
Description: Participants will have scheduled clinic-based visits at 6 and 12 months post-randomization to reinforce self-management strategies and perform hearing aid checks.

Intervention type: OTHER
Group type: OTHER
Intervention: Telehealth audiological rehabilitative service delivery
Description: Participants' scheduled clinic-based visits will be complemented with asynchronous and synchronous telehealth that will allow for routine troubleshooting of communication challenges, hearing aid technical issues, and reinforcement of self-management support strategies. At an initial session, participants will be instructed in the use of a study-provided, internet-enabled tablet device for telehealth sessions, re-introduced to the hearing loss toolkit for self-management and C2Hear Reusable Learning Objects within the context of the telehealth platform, re-evaluated on the Client Oriented Scale of Improvement (COSI) goals. Two remote follow-up sessions will be scheduled 3 and 6 weeks later to confirm participants' comfort with the telehealth platform and then completed every 6 months, in addition to scheduled 6-month clinic-based visits.

Intervention type: OTHER
Group type: OTHER
Intervention: Telehealth audiological rehabilitative service delivery
Description: Participants' scheduled clinic-based visits will be complemented with asynchronous and synchronous telehealth that will allow for routine troubleshooting of communication challenges, hearing aid technical issues, and reinforcement of self-management support strategies. At an initial session, participants will be instructed in the use of a study-provided, internet-enabled tablet device for telehealth sessions, re-introduced to the hearing loss toolkit for self-management and C2Hear Reusable Learning Objects within the context of the telehealth platform, re-evaluated on the Client Oriented Scale of Improvement (COSI) goals. Two remote follow-up sessions will be scheduled 3 and 6 weeks later to confirm participants' comfort with the telehealth platform and then completed every 6 months, in addition to scheduled 6-month clinic-based visits.
Study: NCT06459505

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine or standard Physical Therapy
Description: Participants will undergo physical therapy to stop abnormal movement patterns and restore control over output in the developmental sequence. Therapists will provide cues to elicit basic posture and movement patterns, inhibiting aberrant patterns. The therapy aims to promote normal posture and movement patterns, incorporating the hemiplegic side for symmetry and functional use. Active usage and targeted strengthening activities will be emphasized, with motor performance practice included.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adapted Physical Activity
Description: For Upper extremities, Manual Ability Classification Scale (MACS) is a tool designed to support individuals with hemiplegic cerebral palsy by providing structured support through activities focusing on strength, flexibility, balance, and coordination. Participants at different MACS levels receive tailored treatments, including adaptive tools, task-specific training, assistive gadgets, and functional training. For lower extremities, the therapy will begin on stable support surfaces before progressing to more challenging surfaces such as inflatable cushions, foam pads, or balance discs, focusing on slow and controlled motions for improved body alignment and coordination.
Study: NCT04604275

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sucrase
Description: 1 mL (8,500 I.U.) (one full measuring scoop or 28 drops) per meal or snack for patients up to 15 kg in body weight. 2 mL (17,000 I.U.) for patients over 15kg in body weight. Dosage is 1 or 2 mL (8,500 to 17,000 I.U.) taken orally or by g-tube with each meal or snack diluted in water, milk, or infant formula.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sucrase
Description: 1 mL (8,500 I.U.) (one full measuring scoop or 28 drops) per meal or snack for patients up to 15 kg in body weight. 2 mL (17,000 I.U.) for patients over 15kg in body weight. Dosage is 1 or 2 mL (8,500 to 17,000 I.U.) taken orally or by g-tube with each meal or snack diluted in water, milk, or infant formula.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 1 mL of placebo per meal or snack for patients up to 15 kg in body weight. 2 mL of placebo per meal of snack for patients above 15kg in body weight. Dosage is 1 or 2 mL of placebo taken orally or by g-tube with each meal or snack diluted in water, milk, or infant formula.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 1 mL of placebo per meal or snack for patients up to 15 kg in body weight. 2 mL of placebo per meal of snack for patients above 15kg in body weight. Dosage is 1 or 2 mL of placebo taken orally or by g-tube with each meal or snack diluted in water, milk, or infant formula.
Study: NCT05190211

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telerehabilitation exercise program
Description: TGr will be given online exercises, synchronized 2 days a week, and a home program for 1 day, accompanied by a physiotherapist, via videoconference on the group smartphone.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Videobased exercise program
Description: After 1 session of online simultaneous exercise training in the company of a physiotherapist via videoconference on the smart phone, an exercise video including the exercises will be sent to them and the patients will be asked to do their exercises 3 days a week. The subjects will be asked to keep an exercise diary and the status of the diaries will be followed by calling them once a week.
Study: NCT06553729

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: Vitamin D3 (cholecalciferol), 1600 IU per day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: Vitamin D3 (cholecalciferol), 1600 IU per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotics
Description: Prebiotics (inulin), 10g per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotics
Description: Prebiotics (inulin), 10g per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotics placebo
Description: Prebiotics placebo.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Prebiotics placebo
Description: Prebiotics placebo.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3 placebo
Description: Vitamin D3 placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Vitamin D3 placebo
Description: Vitamin D3 placebo
Study: NCT06288399

Intervention type: OTHER
Intervention: No treatment given
Description: No treatment given
Study: NCT05350332

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Negative Pressure Ventilator
Description: The negative pressure ventilator is an off-the-shelf FDA-approved device designed to treat respiratory patients with hypoventilation syndromes. This ventilator places the torso within a fixed container that is connected to a vacuum source, which inflates the lungs by pulling a negative pressure around the chest and abdomen. After the clinically routine DISE, a negative pressure ventilator will be placed on the participant's chest to increase lung volumes and the DISE evaluation will be repeated to observe changes.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulmonary Function Testing (PFT)
Description: PFT is a routine standardized clinical test evaluating lung function, consisting of two parts: spirometry and body plethysmography. In spirometry, participants breathe through a mouthpiece that measures airflow and volume to determine normal and maximal volume of inspiration/expiration. Body plethysmography is performed to calculate residual lung volumes. Participants enter in an enclosed chamber where they breathe through a mouthpiece. Changes in pressure in the sealed chamber during breathing are used to calculate the volume of air that remains in the lung after expiration. A MiniBox+ device may be used. The MiniBox+ device derives total lung capacity (TLC) during tidal breathing by the analysis of gas pressures and airflows immediately preceding and immediately following airway occlusions to calculate the same measures as conventional PFT analysis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulmonary Function Testing (PFT)
Description: PFT is a routine standardized clinical test evaluating lung function, consisting of two parts: spirometry and body plethysmography. In spirometry, participants breathe through a mouthpiece that measures airflow and volume to determine normal and maximal volume of inspiration/expiration. Body plethysmography is performed to calculate residual lung volumes. Participants enter in an enclosed chamber where they breathe through a mouthpiece. Changes in pressure in the sealed chamber during breathing are used to calculate the volume of air that remains in the lung after expiration. A MiniBox+ device may be used. The MiniBox+ device derives total lung capacity (TLC) during tidal breathing by the analysis of gas pressures and airflows immediately preceding and immediately following airway occlusions to calculate the same measures as conventional PFT analysis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Phrenic Nerve Stimulation
Description: Phrenic nerve stimulation (PNS) will be performed transcutaneously using a commercially available and FDA approved peripheral neurostimulator. (Digitimer DS8R Bipolar Constant Current Stimulator). The neurostimulator consists of a stimulation generating box connected to electrodes that will be placed over the skin of the neck bilaterally over both phrenic nerves where an bipolar electric current will be used to stimulate the phrenic nerve leading to diaphragm contraction.
Study: NCT05168332

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: patellar taping combined with isometric strength training
Description: patellar taping combined with isometric strength training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: patellar taping combined with isometric strength training
Description: patellar taping combined with isometric strength training

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: sham patellar taping combined with isometric strength training
Description: sham patellar taping combined with isometric strength training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sham patellar taping combined with isometric strength training
Description: sham patellar taping combined with isometric strength training
Study: NCT05260385

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KC1036
Description: KC1036 are administered orally QD or BID in 21-day cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KC1036
Description: KC1036 are administered orally QD or BID in 21-day cycles.