TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05977491

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Health care practitioner is informed of POCT results for CT and NG
Description: Molecular, PCR based near-POCT performed by the research assistant on self -collected urine. The outcome is positive or negative

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Health care practitioner is informed of POCT results for CT and NG
Description: Molecular, PCR based near-POCT performed by the research assistant on self -collected urine. The outcome is positive or negative

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Health care practitioner is informed about POCT result for TV and BV
Description: The pH of vaginal secretion is measured from a self-collected swab by the research assistant, and if above 4.5 a dropp of KOH is added. If it smells fishy, the whiff test is positive.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Health care practitioner is informed about POCT result for TV and BV
Description: The pH of vaginal secretion is measured from a self-collected swab by the research assistant, and if above 4.5 a dropp of KOH is added. If it smells fishy, the whiff test is positive.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: addressing psycholsocial problems
Description: 1. Participants screening positive for anxiety, depression or domestic violence will be offered psychological counseling or referral to a crisis management center in the POCT-PLUS arm~2. All participants of the POCT-PLUS arm receive audio- visual and written education on vaginal discharge and antibiotics
Study: NCT05216991

Intervention type: OTHER
Intervention: TetraGraph on dominant hand
Description: Using standard of care TetraGraph device on dominant hand

Intervention type: OTHER
Intervention: TetraGraph on non-dominant hand
Description: Using standard of care TetraGraph device on non-dominant hand
Study: NCT06365476

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: focused extracorporeal shock wave therapy (ESWT)
Description: The focused shockwaves are directed at the affected muscles in the upper limb, specifically targeting the flexor carpi ulnaris, flexor carpi radialis, and flexor digitorum superficialis.
Study: NCT06313021

Intervention type: OTHER
Intervention: Reliability and Validity Study
Description: Reliability and Validity Study
Study: NCT06365476

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: focused extracorporeal shock wave therapy (ESWT)
Description: The focused shockwaves are directed at the affected muscles in the upper limb, specifically targeting the flexor carpi ulnaris, flexor carpi radialis, and flexor digitorum superficialis.
Study: NCT05546801

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: questionnaire
Description: questionnaire on postnatal development
Study: NCT05096169

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clomiphene Citrate 25mg
Description: clomiphene citrate at a dose of 25mg daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clomiphene Citrate 50mg
Description: clomiphene citrate at a dose of 50mg every other day
Study: NCT06494176

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: neVR Fear the Dentist
Description: neVR Fear the DentistTM comprises two major evidence-based interventions. First is a self-administered eHealth app for CBT/ psychoeducation with exposure therapy - delivered via a mobile tablet - that can be completed anywhere. Second is a 1-hr virtual reality exposure treatment (VRET).
Study: NCT04781660

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Implantable Alginate Hydrogel
Description: Implantable Alginate Hydrogel is a single use, multiple component device. It is expected to be used as a space-occupying material implanted into the myocardium to affect the shape of the left ventricle and reduce the clinical symptoms of patients with left ventricular ischemia and non-ischemic cardiomyopathy.~The hydrogel serves as an artificial myocardial filler to stop the continuous expansion of the ventricle and restore it to a more favorable shape and size. The expected clinical effect of the Implanted Alginate Hydrogel is to reduce the clinical symptoms of patients and improve the quality of life by improving the structure and function of the failing heart.
Study: NCT06402994

Intervention type: OTHER
Intervention: Electrophysiological experiment
Description: Neural envelope tracking to conversational speech at different intensities

Intervention type: OTHER
Intervention: Electrophysiological experiment
Description: Neural envelope tracking to conversational speech at different intensities

Intervention type: OTHER
Intervention: Electrophysiological experiment
Description: Neural envelope tracking to conversational speech at different intensities

Intervention type: BEHAVIORAL
Intervention: Speech audiometry
Description: Speech perception assessment at different intensities

Intervention type: BEHAVIORAL
Intervention: Speech audiometry
Description: Speech perception assessment at different intensities
Study: NCT06036147

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Concussion-focused cognitive behavioral therapy
Description: Youth randomized to receive this component will participate in six 30-minute sessions of cf-CBT. The intervention includes modular CBT targeting post-concussive, anxiety and depressive symptoms. In this CBT treatment, the adolescent can be taught coping skills, relaxation strategies, and cognitive strategies to manage their symptoms, while they are encouraged to increase appropriate activation, including pacing of activities. Six sessions from the CHIP Study Cognitive and Behavioral Skills for Concussion Recovery will be chosen by the interventionist based on the youth's goals in the Introduction Session.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Concussion-focused cognitive behavioral therapy
Description: Youth randomized to receive this component will participate in six 30-minute sessions of cf-CBT. The intervention includes modular CBT targeting post-concussive, anxiety and depressive symptoms. In this CBT treatment, the adolescent can be taught coping skills, relaxation strategies, and cognitive strategies to manage their symptoms, while they are encouraged to increase appropriate activation, including pacing of activities. Six sessions from the CHIP Study Cognitive and Behavioral Skills for Concussion Recovery will be chosen by the interventionist based on the youth's goals in the Introduction Session.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Concussion-focused cognitive behavioral therapy
Description: Youth randomized to receive this component will participate in six 30-minute sessions of cf-CBT. The intervention includes modular CBT targeting post-concussive, anxiety and depressive symptoms. In this CBT treatment, the adolescent can be taught coping skills, relaxation strategies, and cognitive strategies to manage their symptoms, while they are encouraged to increase appropriate activation, including pacing of activities. Six sessions from the CHIP Study Cognitive and Behavioral Skills for Concussion Recovery will be chosen by the interventionist based on the youth's goals in the Introduction Session.
Study: NCT05444647

Intervention type: PROCEDURE
Intervention: stool and blood collection
Description: Patients will collect fecal and blood samples prior to treatment and at the time of response evaluation, and completion of therapy using a standard stool-collection-kit. At the day of stool sampling, patients fill out a brief questionnaire about established factors that can change the microbiome such concurrent use of antibiotics and proton pump inhibitors.
Study: NCT04981704

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Poziotinib
Description: Poziotinib Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Poziotinib
Description: Poziotinib Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Poziotinib
Description: Poziotinib Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Itraconazole Oral solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenytoin
Description: Phenytoin Capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paroxetine
Description: Paroxetine Tablets
Study: NCT05119504

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Commitment
Description: During the 90-minute, one-on-one interventionist led session, participants will learn three inter-related acceptance-based techniques tailored for coping with physical discomfort and negative affect during physical activity. (1) cognitive defusion (i.e., disentangling physical sensations and thoughts from behavior), (2) acceptance (i.e., increasing willingness to experience unpleasant physical sensations/negative affect without trying to change or control them), and (3) valued action (i.e., evaluating the role of physical activity as a valued behavior). Participants will be taught these techniques via didactic instruction, metaphors, and experiential activities.~All participants will receive a two-week physical activity prescription based on national guidelines recommending 150 minutes of at least moderate intensity physical activity per week.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Multi-Health Behavior
Description: The multi health behavior condition will include didactic material focused broadly on healthy lifestyle recommendations including physical activity. It will also emphasize that physical activity is one of several interconnected health behaviors including balanced diet, sleep, stress management. All participants will receive a two-week physical activity prescription based on national guidelines recommending 150 minutes of at least moderate intensity physical activity per week.
Study: NCT04731662

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Short sleep
Description: 6-hours time-in-bed during weeknights
Study: NCT06036147

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care management
Description: In the CM component, parents are provided support regarding advocating for their child's needs across different contexts in the healthcare system, school and athletic departments (including guidance regarding medication referrals), using applied problem-solving together with the skills coach to address emergent needs. Adolescents can also be involved in CM, if developmentally appropriate based on their age, independence, and interest. Of note, while the CM component engages youth and parents, treatment effects are hypothesized to result from facilitating access to supportive services including medication referrals at the organizational level. Families randomized to receive this component will participate in six 30-minute sessions of CM, following the guidelines in the CHIP Care Management Manual.
Study: NCT04731662

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Variable short sleep
Description: Variable hours of time-in bed during weeknights
Study: NCT05503732

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Energy Drink
Description: Two 16-oz energy drinks consumed orally to be finished approximately 4 hours prior to bed

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Energy Drink
Description: Two 16-oz energy drinks consumed orally to be finished approximately 4 hours prior to bed
Study: NCT06036147

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care management
Description: In the CM component, parents are provided support regarding advocating for their child's needs across different contexts in the healthcare system, school and athletic departments (including guidance regarding medication referrals), using applied problem-solving together with the skills coach to address emergent needs. Adolescents can also be involved in CM, if developmentally appropriate based on their age, independence, and interest. Of note, while the CM component engages youth and parents, treatment effects are hypothesized to result from facilitating access to supportive services including medication referrals at the organizational level. Families randomized to receive this component will participate in six 30-minute sessions of CM, following the guidelines in the CHIP Care Management Manual.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care management
Description: In the CM component, parents are provided support regarding advocating for their child's needs across different contexts in the healthcare system, school and athletic departments (including guidance regarding medication referrals), using applied problem-solving together with the skills coach to address emergent needs. Adolescents can also be involved in CM, if developmentally appropriate based on their age, independence, and interest. Of note, while the CM component engages youth and parents, treatment effects are hypothesized to result from facilitating access to supportive services including medication referrals at the organizational level. Families randomized to receive this component will participate in six 30-minute sessions of CM, following the guidelines in the CHIP Care Management Manual.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care management
Description: In the CM component, parents are provided support regarding advocating for their child's needs across different contexts in the healthcare system, school and athletic departments (including guidance regarding medication referrals), using applied problem-solving together with the skills coach to address emergent needs. Adolescents can also be involved in CM, if developmentally appropriate based on their age, independence, and interest. Of note, while the CM component engages youth and parents, treatment effects are hypothesized to result from facilitating access to supportive services including medication referrals at the organizational level. Families randomized to receive this component will participate in six 30-minute sessions of CM, following the guidelines in the CHIP Care Management Manual.
Study: NCT05503732

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo Drink
Description: Two 16-oz identical looking placebo drink without caffeine consumed orally to be finished approximately 4 hours prior to bed

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo Drink
Description: Two 16-oz identical looking placebo drink without caffeine consumed orally to be finished approximately 4 hours prior to bed
Study: NCT06349473

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR604
Description: SR604 will be administered as SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered as single SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered as single SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered as single SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered as single SC injection.
Study: NCT05623085

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: Individuals in this group will be given 8-week individualized exercise according to the Karvonen protocol (heart rate reserve percentage-% HR). Exercise training will be 30 minutes at 50% of HR between weeks 0-2, 45 minutes at 50% of HR between weeks 2-4, 45 minutes at 60% of HR between weeks 4-6 and 6-8 weeks It will be done on the treadmill 3 days a week, for 60 minutes at 60% of HR between weeks. The treadmill speed will be adjusted during exercise to maintain the set target heart rate level.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Yoga exercise
Description: Individuals in this group will be given 8-week individualized yoga exercise including stretching, relaxing, strength training. Exercise training will be done 3 days a week. The duration of the exercise will be adjusted to be the same as the aerobic exercise group.
Study: NCT06118281

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ziltivekimab
Description: Ziltivekimab will be adminsitered subcutaneously as an initial loading dose of Dose 1 followed by a maintenance dose of Dose 2 once- monthly.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo matched to ziltivekimab will be adminsitered subcutaneously as an initial loading dose followed by a maintenance dose once-monthly.
Study: NCT05704829

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab deruxtecan
Description: T-DXd i.v.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab deruxtecan
Description: T-DXd i.v.

Intervention type: DRUG
Group type: OTHER
Intervention: Standard-of-Care
Description: Chemotherapy+T+P

Intervention type: DRUG
Group type: OTHER
Intervention: Standard-of-Care
Description: Chemotherapy+T+P
Study: NCT05447221

Intervention type: DIAGNOSTIC_TEST
Intervention: The diagnosis of Artificial Intelligence and pathologists
Description: Pathologists and AI will assess the severity of intestinal metaplasia and judge the tumor area of whole slide images of gastric biopsy specimens independently. In addition, the pathologists can not see the diagnosis of AI.
Study: NCT06067659

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Extracorporeal shock wave therapy
Description: ESWT (EMS Swiss DolorClast® Classic) application will be applied to patients in groups 1 and 3 with a frequency of 15 Hz, a 2000 shock wave and an energy density of 2.5 bar. In practice, patients will be asked to lie in the prone position and keep the knee and hip joints in a neutral position. By placing a towel roll under the ankle, the heel will be stabilized to be applied. Using the ultrasound gel as an intermediate, the ESWT device will be applied to the medial part of the calcaneus.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Extracorporeal shock wave therapy
Description: ESWT (EMS Swiss DolorClast® Classic) application will be applied to patients in groups 1 and 3 with a frequency of 15 Hz, a 2000 shock wave and an energy density of 2.5 bar. In practice, patients will be asked to lie in the prone position and keep the knee and hip joints in a neutral position. By placing a towel roll under the ankle, the heel will be stabilized to be applied. Using the ultrasound gel as an intermediate, the ESWT device will be applied to the medial part of the calcaneus.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiology taping
Description: The material used in the taping will be 5 cm wide and 0.5 mm thick Kinesio® Tape. In practice, the patients were placed in the prone position and the ankle would be dorsiflexed at 10 degrees, and the band would be divided into 4 equal parts on the metatarsals of the 1/3 of the foot from the cruis, starting from the calcaneus. Then, taping will be performed from the medial to the lateral of the calcaneus, passing over the area where the pain is intense. Patients will be asked not to remove the applied tape for 3 days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiology taping
Description: The material used in the taping will be 5 cm wide and 0.5 mm thick Kinesio® Tape. In practice, the patients were placed in the prone position and the ankle would be dorsiflexed at 10 degrees, and the band would be divided into 4 equal parts on the metatarsals of the 1/3 of the foot from the cruis, starting from the calcaneus. Then, taping will be performed from the medial to the lateral of the calcaneus, passing over the area where the pain is intense. Patients will be asked not to remove the applied tape for 3 days.
Study: NCT05940636

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Activity-based rehabilitation+electrical stimulation
Description: Balance training will occur three times per week for four weeks, totaling 12 two-hour sessions. In both groups, you will be asked to stand on a force plate while playing visual feedback training (VFT) games as part of the standing balance training. A force plate is similar to a bathroom scale that you can stand on which measures your body sway during movement. Visual feedback training (VFT) is a type of activity that includes weight-shifting movements in the upright stance. VFT will be done in both groups. There will be different games as shown in figure 1 and the order of the games will be randomly chosen in each session. During each game, there will be targets that will be presented on the screen and you will have to navigate toward them . You will be able to rest between games as needed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activity-based rehabilitation+electrical stimulation
Description: Balance training will occur three times per week for four weeks, totaling 12 two-hour sessions. In both groups, you will be asked to stand on a force plate while playing visual feedback training (VFT) games as part of the standing balance training. A force plate is similar to a bathroom scale that you can stand on which measures your body sway during movement. Visual feedback training (VFT) is a type of activity that includes weight-shifting movements in the upright stance. VFT will be done in both groups. There will be different games as shown in figure 1 and the order of the games will be randomly chosen in each session. During each game, there will be targets that will be presented on the screen and you will have to navigate toward them . You will be able to rest between games as needed.
Study: NCT05362175

Intervention type: DEVICE
Intervention: Obstetric ultrasound
Description: ultrasound measurement of the cross sectional area of umbilical cord within 1 cm from the cord insertion in to fetal abdomen and the standard Hadlock's formula
Study: NCT05072041

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nexsphere™
Description: Nexsphere™ is a yellow powder, made of 100% hydrophilic gelatin. It is used to make a suspension by mixing a contrast agent and physiological saline. The indications are hepatic artery chemoembolization, uterine artery embolization, prostate artery embolization, and treatment of various hemorrhagic diseases. It physically embolizes blood vessels and is decomposed within 4-8 weeks after intravascular injection.
Study: NCT06184503

Intervention type: DRUG
Intervention: Velmanase Alfa
Description: Lamzede® (velmanase alfa, henceforth referred to as Lamzede) is a recombinant human lysosomal alpha-mannosidase product developed as an intravenous enzyme replacement therapy (ERT) for the treatment of alpha-mannosidosis.