TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06638944

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Standard-of-care treatment
Description: Participants in this intervention will complete the same standardized behavioral swallowing rehabilitation protocol and in the same frequency as the sEMG biofeedback intervention groups but WITHOUT a device. That is, they will complete the protocol for 12 weeks with weekly (once per week) treatment sessions completed in-person and 3 days of home practice per week. For this intervention group, patients use a visual analog scale and a timer as feedback tools, as frequently done in clinical practice where sEMG devices are not widely available.
Study: NCT06637020

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HDM1005 injection or placebo
Description: Within each cohort, subjects are randomized in a 4:1 ratio to receive either HDM1005 injection or placebo subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HDM1005 injection or placebo
Description: Within each cohort, subjects are randomized in a 4:1 ratio to receive either HDM1005 injection or placebo subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HDM1005 injection or placebo
Description: Within each cohort, subjects are randomized in a 4:1 ratio to receive either HDM1005 injection or placebo subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HDM1005 injection or placebo
Description: Within each cohort, subjects are randomized in a 4:1 ratio to receive either HDM1005 injection or placebo subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HDM1005 injection or placebo
Description: Within each cohort, subjects are randomized in a 4:1 ratio to receive either HDM1005 injection or placebo subcutaneously.
Study: NCT06644664

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Education
Description: Receive control MMS messages

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Ancillary studies

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking Cessation Intervention
Description: Receive AR MMS messages

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking Cessation Intervention
Description: Receive RR MMS messages

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking Cessation Intervention
Description: Receive smoking cessation resources

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking Cessation Intervention
Description: Receive smoking cessation resources

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Smoking Cessation Intervention
Description: Receive smoking cessation resources

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Text Message-Based Navigation Intervention
Description: Receive check-in text message
Study: NCT06069544

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BNT165e
Description: Multi-antigen RNA-based vaccine for active immunization against malaria administered as intramuscular injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Isotonic NaCl solution (0.9%)
Study: NCT06054477

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALE.C04
Description: Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALE.C04
Description: Q3W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ALE.C04
Description: Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200mg Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200mg Q3W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pembrolizumab
Description: 200mg Q3W
Study: NCT05203146

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PIMPmyHospital (mobile health tool)
Description: Each participant will first be asked to retrieve a factious patient's laboratory results on the app when randomly made available, and then reach a colleague (role played by a study investigator) when asked to do so by a text message on the app.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional method
Description: Each participant will first be asked to retrieve a factious patient's laboratory results from the emergency department's computerized patient data system when randomly made available, and then contact a colleague (role played by a study investigator) when asked to do so (request made by a second study investigator).
Study: NCT06644664

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Text Message-Based Navigation Intervention
Description: Receive check-in text message
Study: NCT06556524

Intervention type: BEHAVIORAL
Intervention: observation
Description: Behavioral observation and trauma measurement in live mannequin application
Study: NCT06556758

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stripping massage + conventional therapy
Description: Stripping massage on rhomboid major and minor active trigger point in the direction of muscle fiber from origin to insertion of muscle. Frequency: 3 minutes for 3 times/week for 4 consecutive weeks. Conventional PT including Hot pack for 10 minutes + ischemic compression for 90 secs + CPA glides grade 3 kaltenborn mobilization on thoracic T1 to T4 (5 reps x 1 set) Frequency: 3 times/ week for 4 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional therapy
Description: conventional therapy including Hot pack for 10 minutes + ischemic compression for 90 secs + CPA glides grade 3 kaltenborn mobilization on thoracic T1 to T4 (5 reps x 1 set ) Frequency : 3 times/ week for 4 weeks
Study: NCT04903665

Intervention type: DEVICE
Intervention: Multi-cancer early detection test
Description: Blood collection and multi-cancer early detection testing

Intervention type: DEVICE
Intervention: Multi-cancer early detection test
Description: Blood collection and multi-cancer early detection testing
Study: NCT05938530

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sirolimus drug-coated balloon
Description: The effectiveness of sirolimus coated balloon in patients with dialysis access dysfunction has been shown in a small pilot study in the salvage of thrombosed arteriovenous graft.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Stent graft
Description: Stent graft has been shown to be superior than plain balloon angioplasty in the treatment of AVG dysfunction.
Study: NCT05044091

Intervention type: DRUG
Intervention: PARP inhibitor
Description: Ovarian/fallopian tube/primary peritoneal cancer patients with PARP inhibitors according to the NCCN guideline and their instructions
Study: NCT06556264

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dupilumab
Description: Dupilumab 300mg every 2 weeks for 24 weeks

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 300mg every 2 weeks for 24 weeks
Study: NCT06644664

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Text Message-Based Navigation Intervention
Description: Receive check-in text message
Study: NCT06643468

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: participants will receive immediate implant with nano-crystalline putty hydroxyapatite as bone graft and collagen membrane.
Description: 1. Injection of local anesthetic Articaine hydrochloride 4% with Epinephrine (1:100,000).~2. Atraumatic removal of remaining root or tooth then implant will be placed according to the standard protocol.~3. Sulcular incision with be made 15c blade .~4. Implant placement with copious irrigation.~5. Membranes placement: collagen followed by insertion of nano-crystalline putty hydroxyapatite.~6. Customized healing abutment application.~7. Suturing of wound edges with 0.5 suture around the customized healing abutment.
Study: NCT04952467

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 14C-XEN1101
Description: Subjects will receive a single oral administration of a capsule containing 20 mg XEN1101
Study: NCT06265168

Intervention type: OTHER
Intervention: Simulation
Description: Physicians will participate in a simulated scenario of an adult comatose patient. The intervention will be presented as a learning situation where the physician interacts with a high-fidelity mannequin. The mannequin simulating the patient will manifest a Glasgow Coma Score of 3 (improving over time to a GCS of 4) and a range of physiological and pathological symptoms. Physicians will have access to emergency equipment, including intubation equipment, a defibrillator, and medications. A trained nurse will be present to assist with the simulation. After 20 minutes the patient will regain consciousness in order to avoid a frustrating experience for the physicians. After simulation termination, a senior physician will join the resident and ask him to report the current scenario and will stop the simulation. The entire scenario will be video-recorded.
Study: NCT05849688

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Designed Physical Therapy Program
Description: The designed physical therapy program include gentle stretching exercises for biceps brachii, hamstrings and calf muscles bilaterally (5 times for every muscle) and isometric muscle contraction for quadriceps, hamstrings, anterior tibial group, calf muscles, biceps and triceps muscles (5 times for every muscle). Also, diaphragmatic breathing exercises will be applied.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bicycle Ergometry Training
Description: The designed physical therapy program include gentle stretching exercises for biceps brachii, hamstrings and calf muscles bilaterally (5 times for every muscle) and isometric muscle contraction for quadriceps, hamstrings, anterior tibial group, calf muscles, biceps and triceps muscles (5 times for every muscle). Also, diaphragmatic breathing exercises will be applied + bicycle ergometry training
Study: NCT06676449

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunotherapy
Description: PD-1 inhibitors will be administered intravenously, a fixed dose of 200 mg, once every 3 weeks for 1 year.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: chemotherapy: Paclitaxel/Cisplatin
Description: Paclitaxel 135mg/m2 d1, cisplatin 25mg/m2 d1-3, once every 3 weeks for 4 cycles.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: chemotherapy: Paclitaxel/Cisplatin
Description: Paclitaxel 135mg/m2 d1, cisplatin 25mg/m2 d1-3, once every 3 weeks for 4 cycles.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: TDLN-sparing RT
Description: TDLN-sparing radiotherapy 50.4Gy/28Fx.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: TDLN-sparing RT
Description: TDLN-sparing radiotherapy 50.4Gy/28Fx.
Study: NCT06602414

Intervention type: PROCEDURE
Intervention: Conservative treatment
Description: Conservative treatment instead of surgical repair
Study: NCT06677840

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: probiotic (GKB7/placebo)
Description: The objectives of this double-blind randomized placebo-controlled trial are to evaluate the tolerability, safety, and efficacy of the probiotic intervention with Clostridium butyricum GKB7 among 90 4-15-year-old children and adolescents with a clinical diagnosis of ASD according to the DSM-5

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: probiotic (GKB7/placebo)
Description: The objectives of this double-blind randomized placebo-controlled trial are to evaluate the tolerability, safety, and efficacy of the probiotic intervention with Clostridium butyricum GKB7 among 90 4-15-year-old children and adolescents with a clinical diagnosis of ASD according to the DSM-5
Study: NCT06677632

Intervention type: OTHER
Intervention: Palmitoylation Enzyme Expression Profiling Study
Description: The expression of 23 zDHHC enzymes will be studied in human post-mortem hippocampi of AD patients and controls that have already been collected from UK brain biobanks. zDHHC enzymes will be analyzed at both mRNA and protein levels by Real Time PCR and Western blotting techniques, respectively
Study: NCT06678087

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: motherhood preparation meditation training prepared with the thetahealing meditation method
Description: With Birth and Motherhood Preparation Meditation, all physiological and psychological reasons causing fear of birth will be addressed. How to do the meditation will be taught by the practitioner in the course.~The root belief analysis study for each topic is carried out with the questions of who, what, when, where, why and how. Then, the reprogramming work that allows the change of that belief, feeling, emotion will be done with methods specific to the technique.~The topics to be worked on during meditation each week are listed below. Each week, pregnant women will be given a 15-minute meditation homework per day until the next week regarding the topic worked on.~All meditations begin with relaxation and breathing exercises. In each meditation, the emotion and root-belief analysis related to the relevant topic will be done by the practitioner.~With this application, it is aimed to accelerate the change in the mind with positive language and regular repetition.

Intervention type: OTHER
Group type: OTHER
Intervention: pregnancy school,
Description: In the pregnancy school, an informational support training is provided to pregnant women and their families to ensure that the pre-pregnancy, pregnancy and birth process is passed in a healthy and conscious manner.~The training content includes:~Reproductive organs and development, Nutrition during pregnancy and puerperium, Common problems during pregnancy, Physiological changes, Non-formological methods, Breathing techniques during birth, Anesthetic methods, Birth methods and techniques, Postpartum and baby care, Newborn Care / Problems, Home-Bag-Hospital preparation, Breast milk - Its importance - Breastfeeding, Family planning topics are given five days a week for 2 hours.
Study: NCT06678906

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention arm
Description: All patients in the intervention group will benefit from the standard information phase on physical activity and sedentary behavior, as well as personalized support for behavior change in the form of a serious game and remote coaching.
Study: NCT06616441

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Group (A) only will receive intra-peritoneal 40 ml bupivacaine 0.2%, after laparoscopic procedure before removing trocars.
Study: NCT06678126

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Prostate and Pelvic Nodes Radiotherapy
Description: 60 Gy prostate and 44 Gy pelvic nodes with 20 fractions

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Prostate and Pelvic Nodes Radiotherapy
Description: 60 Gy prostate and 44 Gy pelvic nodes with 20 fractions

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Prostate and Pelvic Nodes Radiotherapy
Description: 60 Gy prostate and 44 Gy pelvic nodes with 20 fractions

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Prostate and Pelvic Nodes Radiotherapy
Description: 60 Gy prostate and 44 Gy pelvic nodes with 20 fractions
Study: NCT06678113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BSG005
Description: Single arm dose escalation in patients with invasive fungal infection
Study: NCT06678074

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atibuclimab (IC14), 20 mg/kg intravenously, once
Description: monoclonal antibody against CD14

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo, 150 mL intravenously, once
Description: sterile normal saline for injection
Study: NCT06643468

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: participants will receive immediate implant with nano-crystalline putty hydroxyapatite as bone graft and ALB- PRF as membrane.
Description: 1. Injection of local anesthetic Articaine hydrochloride 4% with Epinephrine (1:100,000).~2. Atraumatic removal of remaining root or tooth then implant will be placed according to the standard protocol.~3. Sulcular incision with be made 15c blade without vertical releasing incision.~4. Implant placement with copious irrigation.~5. Membranes placement: ALB-PRF followed by insertion of nano-crystalline putty hydroxyapatite..~6. Customized healing abutment application.~7. Suturing of wound edges with 0.5 suture around the customized healing abutment.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: participants will receive immediate implant with beta-tricalcium phosphate + calcium sulphate bone graft and collagen membrane.
Description: 1. Injection of local anesthetic Articaine hydrochloride 4% with Epinephrine (1:100,000).~2. Atraumatic removal of remaining root or tooth then implant will be placed according to the standard protocol.~3. Sulcular incision with be made 15c blade .~4. Implant placement with copious irrigation.~5. Membranes placement: collagen followed by insertion of eta-tricalcium phosphate + calcium sulphate bone graft.~6. Customized healing abutment application.~7. Suturing of wound edges with 0.5 suture around the customized healing abutment.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: participants will receive immediate implant with beta-tricalcium phosphate + calcium sulphate bone graft and ALB-PRF membrane.
Description: 1. Injection of local anesthetic Articaine hydrochloride 4% with Epinephrine (1:100,000).~2. Atraumatic removal of remaining root or tooth then implant will be placed according to the standard protocol.~3. Sulcular incision with be made 15c blade .~4. Implant placement with copious irrigation.~5. Membranes placement: ALB-PRF followed by insertion of eta-tricalcium phosphate + calcium sulphate bone graft.~6. Customized healing abutment application.~7. Suturing of wound edges with 0.5 suture around the customized healing
Study: NCT06644339

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Voice assistant
Description: Robotic remote monitoring of patients using unique algorithms developed for virtual operator speech technology and a BI system by voice commands on the question-answer principle. It allows us to automate data collection and obtain information about the patient's well-being and his vital signs (blood pressure, heart rate, weight) depending on disease.~Follow-up and management of disease provided by specialists at participating institutions.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Voice assistant
Description: Robotic remote monitoring of patients using unique algorithms developed for virtual operator speech technology and a BI system by voice commands on the question-answer principle. It allows us to automate data collection and obtain information about the patient's well-being and his vital signs (blood pressure, heart rate, weight) depending on disease.~Follow-up and management of disease provided by specialists at participating institutions.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Voice assistant
Description: Robotic remote monitoring of patients using unique algorithms developed for virtual operator speech technology and a BI system by voice commands on the question-answer principle. It allows us to automate data collection and obtain information about the patient's well-being and his vital signs (blood pressure, heart rate, weight) depending on disease.~Follow-up and management of disease provided by specialists at participating institutions.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Voice assistant
Description: Robotic remote monitoring of patients using unique algorithms developed for virtual operator speech technology and a BI system by voice commands on the question-answer principle. It allows us to automate data collection and obtain information about the patient's well-being and his vital signs (blood pressure, heart rate, weight) depending on disease.~Follow-up and management of disease provided by specialists at participating institutions.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Voice assistant
Description: Robotic remote monitoring of patients using unique algorithms developed for virtual operator speech technology and a BI system by voice commands on the question-answer principle. It allows us to automate data collection and obtain information about the patient's well-being and his vital signs (blood pressure, heart rate, weight) depending on disease.~Follow-up and management of disease provided by specialists at participating institutions.
Study: NCT06643286

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digizorg Melanoma app
Description: The Digizorg Melanoma app is a digital survivorship care plan, in which ellaborated information regarding diagnosis, treatment and follow-up and supportive care, adjusted to one's personal preferences and disease characteristics, is offered in the form of a mobile application.
Study: NCT06643442

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin Tablets
Description: Empagliflozin 10mg p.o. once daily (commercially available tablet)
Study: NCT06643559

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: cognitive rehabilitation
Description: Cognitive rehabilitation started to one group at the beginning of the antiseizure medicine. Participants underwent computer-based cognitive rehabilitation for 3 sessions per week, with each session lasting an average of 60 minutes. Before the sessions, all participants were given detailed information about the programme and its use. The rehabilitation process was carried out in three areas of cognitive functions: memory, executive functions, and language skills.
Study: NCT06644872

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bedrest
Description: Investigation of the effect of short-term bed rest (3 hours) on heart function, measured by cardiac magnetic resonance, in healthy participants ( males and females)
Study: NCT06643494

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: N-111
Description: A combination of Acetogenins

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo