TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04806555

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Compression ultrasound examination
Description: After successful revascularisation for acute ischemia and clinical suspicion of acute compartment syndrome, compression ultrasound (CU) will be performed in OR followed by standard intra-compartmental measurement. Two physicians will perform two subsequent measurements of the affected limb after revascularisation. The unaffected limb will be examined once to obtain baseline elasticity ratio values. All CU examinations will be documented in PACS (picture archiving and communication system) and evaluated after ICP measurement, and if necessary, fasciotomy is performed.
Study: NCT06138496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab Combined With Lenvatinib
Description: 3.7.1 Lenvatinib Treatment Lenvatinib (8mg \[body weight \< 60 kg\] or 12 mg \[body weight ≥ 60 kg\]) orally once daily, with or without food.~3.7.2 Intravenous Infusion of Cardonilli (Injection) Infuse Cardonilli at a dose of 6mg/kg intravenously every two weeks, constituting one treatment cycle, a total of 6 cycles.
Study: NCT05445791

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin Hydrochloride
Description: Metformin 500 mg twice daily until disease progression.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 500 mg twice daily until disease progression
Study: NCT04607317

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise program
Description: a telehealth-delivered exercise program with the goal of progressing to 150 min/week (5 days per week, 30 minutes of steady state walking per day)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Coach
Description: The coach will work directly with each participant during their once-weekly virtual 1:1 meeting to progress intensity and duration. Participants will meet with the coach to review a brief social cognitive theory-based module, which will provide education on core behavior change concepts and the benefits of physical activity for those with epilepsy. The coach will review the previous week's exercise during meetings, and will then work with the participant to revise and reset goals for the coming week.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Information
Description: Participants will be contacted by a study coordinator via telephone every 2 weeks for health education. During this time, they will review resources and healthy lifestyle guidelines for people with epilepsy, including healthy diet, medication compliance, seizure precautions, stress management, and sleep hygiene.
Study: NCT00992472

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prochlorperazine suppositories, 25mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Compazine® suppositories, 25mg
Study: NCT05860309

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: quadratous lumborum block
Description: The patient will be placed in the lateral position, after sterilization.. QLB will be done using ultrasound, The probe will be positioned superior to the iliac crest, in the transverse orientation, at the posterior axillary line. The Shamrock sign will be identified at the L4 level, and the insulated nerve block needle will be advanced from posterior to anterior, through the QL muscle, until the needle tip is visualized in the interfascial plane between the QL muscle and psoas muscle. As the correct needle placement is confirmed with 2-3 mL of saline, 20 mL of 0.25% bupivacaine will be injected ensuring that the psoas muscle will be pushed deeply.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: quadratous lumborum block
Description: The patient will be placed in the lateral position, after sterilization.. QLB will be done using ultrasound, The probe will be positioned superior to the iliac crest, in the transverse orientation, at the posterior axillary line. The Shamrock sign will be identified at the L4 level, and the insulated nerve block needle will be advanced from posterior to anterior, through the QL muscle, until the needle tip is visualized in the interfascial plane between the QL muscle and psoas muscle. As the correct needle placement is confirmed with 2-3 mL of saline, 20 mL of 0.25% bupivacaine will be injected ensuring that the psoas muscle will be pushed deeply.
Study: NCT04549129

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding education video
Description: An introductory video (15 minutes) gives an overview of these ABCs (video titled Term baby which are further taught through brief text summaries (150-200 words) and short instructional videos (2-6 minutes).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding website
Description: The website firstdroplets.com is designed for prenatal education, focusing on the ABCs of breastfeeding that come before D (delivery) - attachment (latch), breastmilk production, and calories (transfer of milk to baby).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual breastfeed education
Description: The usual breastfeed education includes brief counseling by study staff and provision of handouts on latch/positioning and common first week breastfeeding advice
Study: NCT06064916

Intervention type: DIAGNOSTIC_TEST
Intervention: Visual Acuity
Description: Monocular and binocular measurement of distance, intermediate, and near visual acuity

Intervention type: DIAGNOSTIC_TEST
Intervention: Defocus Curve
Description: Measurement of a defocus curve

Intervention type: OTHER
Intervention: Intraocular Lens Satisfaction (IOLSAT) Questionnaire
Description: Self-reported post-operative patient satisfaction with vision after surgery

Intervention type: OTHER
Intervention: Quality of Vision After Surgery (QUVID) Questionnaire
Description: Self-reported post-operative patient vision quality after surgery

Intervention type: OTHER
Intervention: Visual Disturbance Questionnaire
Description: Questionnaire of self-reported visual disturbances of patients

Intervention type: DIAGNOSTIC_TEST
Intervention: Topography and Tomography
Description: Topography and tomography measurements with Atlas, iTrace, and/or Pentacam
Study: NCT04981990

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Single lung ventilation by double lumen endotracheal tube
Description: Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Two lung ventilation by conventional single lumen endotracheal tube
Description: Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field
Study: NCT06435897

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: fetal MSCs combined with 4SCAR T cells
Description: Infusion of 4SCAR T cells at 10\^6 cells/kg body weight and MSCs at 3x10\^6 cells via IV
Study: NCT04526769

Intervention type: DIAGNOSTIC_TEST
Intervention: Tear Collection
Description: A microcapillary tube will be placed at the corner of the eyelid so tears can be absorbed to the tube without causing any trauma. The tube will be placed in a transfer tube. Standard virus sampling swabs will be used to collect samples from the same patient's nasopharynx. RT-PCR will be run to determine virus yield in each sample.~For the second part of the study, IHC staining will be done on the existing ocular tissue pathology slides to detect the expression of ACE2 and other cell surface and intracellular receptors. The investigators will use existing UMN ocular pathology lab and Lion's Eye Bank tissue samples. These are banked tissue samples that were collected and examined previously and then the remaining tissue samples were stored.
Study: NCT05568303

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT techniques
Description: through CBT sessions , the participants apply problem solving process in managing their stressors . examining the role of cognitions, emotions, and behaviors to form cause and effect relationship of participants psychological distress
Study: NCT05241548

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: BMAC on PCL Scaffold
Description: Horizontal ridge augmentation in aesthetic zone by using bone marrow aspirate concentrate on PCL scaffold
Study: NCT05219552

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: personalized lactation support
Description: Our intervention design aims to address food insecurity and mental health by providing an unconditional cash transfer and lactation support across the perinatal period, when women are out of the workforce caring for their infant child. The study will include pregnant women living with HIV in Kisumu Kenya. The lactation support component will focus on milk insufficiency primarily as that has been a main concern of women we've worked with in this population, in addition to general breastfeeding support which will all be delivered in one-on-one sessions with a professional lactation consultant. The cash transfer will be delivered to women from their third trimester to 6 months postpartum. The amount of the cash transfer is based on preliminary data and consultation with key stakeholders to determine a reasonable and sufficient amount to basic living expenses during this period.
Study: NCT05874193

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin
Description: Belantamab mafodotin 2.5mg/kg in 42-day cycles. Every 6 weeks until PD, unacceptable toxicity or withdrawal of consent, whichever comes first
Study: NCT05755243

Intervention type: DEVICE
Intervention: glucose sensor
Description: skin biopsy (punch)
Study: NCT05741749

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Socket Seal Abutment
Description: Customized Healing Abutment

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Socket Seal Abutment
Description: Customized Healing Abutment
Study: NCT06517355

Intervention type: OTHER
Intervention: In this research, the procedure under study is represented:
Description: * On the one hand, by carrying out sexology consultations which consist of individual interviews with a qualified sexologist nurse.~* Secondly, questionnaires to assess quality of life and sexual function, to be completed by patients during standard follow-up consultations; and a questionnaire on satisfaction with sexological follow-up, to be completed by patients and their partners (if applicable) during the last standard follow-up consultation.
Study: NCT06353555

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Euthyrox
Description: Upon discovering low T3 or low T4 levels, administer oral levothyroxine sodium tablets daily. If accompanied by a decrease in TSH, the regimen is 100μg qd (for individuals weighing \<75kg) or 150μg qd (for individuals weighing \>75kg). If not accompanied by a decrease in TSH, the regimen is 50μg qd. However, if thyroid function does not significantly improve within 3 days of medication, the regimen is adjusted to 100μg qd. Treatment should continue until transfer out of the NICU or discharge, with a minimum duration of 7 days.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Euthyrox
Description: Patient will not receive the oral levothyroxine sodium tablets.
Study: NCT04502680

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eribulin Mesylate
Description: Eribulin mesylate 1.4mg/m2, administered intravenously on Days 1 and 8 of each 21 day cycle.
Study: NCT06458478

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hyper-oxygenated gel
Description: Novox drop is a medical device (CE certified, class II b, non-invasive) based on oxygen-enriched olive oil (Excipients: Mint essential oil (2%), Stevia extract (1%)). Mechanism of action: facilitate the healing process by creating, thanks to the release of reactive oxygen species (ROS), a microenvironment favorable to the activation of the microcirculation and at the same time unfavorable to the proliferation of pathogens. Furthermore, it has a film-forming, protective, barrier and soothing action thanks to its oily nature.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: glycerin based gel
Description: The placebo consists of a viscous, colorless and transparent gel, based on glycerin (Conformity:FUI).
Study: NCT04900727

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05699694

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: StemRegen product
Description: Products will be consumed orally in capsules with a glass of water. Six capsules per day will be consumed daily for 6 month. Two main administration schedules are possible:~Two in the morning, 2 at noon, and 2 in the evening at each meal depending on individual habits of the volunteers to reduce non-compliance.
Study: NCT06464978

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Stapler Reinforcement Patch
Description: Participants in this group will receive gastrojejunostomy with the use of stapler reinforcement patches.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Stapler
Description: Participants in this group will receive gastrojejunostomy with the use of Standard Stapler
Study: NCT05428397

Intervention type: DIAGNOSTIC_TEST
Intervention: Iopromide (Ultravist, BAY86-4877)
Description: X-Ray/CT Diagnostic Imaging

Intervention type: DIAGNOSTIC_TEST
Intervention: Iopromide (Ultravist, BAY86-4877)
Description: X-Ray/CT Diagnostic Imaging
Study: NCT04794569

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tinzaparin
Description: low molecular weight heparin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rivaroxaban
Description: direct oral anticoagulant
Study: NCT05354414

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Administered as specified in the treatment arm.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Administered as specified in the treatment arm.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Administered as specified in the treatment arm.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Administered as specified in the treatment arm.
Study: NCT05097872

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diet
Description: Diet excluding either trigger and sham nutrient in a blinded crossover fashion (CLE positive individuals with identified trigger) or wheat and soy in a blinded crossover fashion (CLE negative individuals without identified trigger)

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Diet
Description: Diet excluding either trigger and sham nutrient in a blinded crossover fashion (CLE positive individuals with identified trigger) or wheat and soy in a blinded crossover fashion (CLE negative individuals without identified trigger)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diet
Description: Diet excluding either trigger and sham nutrient in a blinded crossover fashion (CLE positive individuals with identified trigger) or wheat and soy in a blinded crossover fashion (CLE negative individuals without identified trigger)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diet
Description: Diet excluding either trigger and sham nutrient in a blinded crossover fashion (CLE positive individuals with identified trigger) or wheat and soy in a blinded crossover fashion (CLE negative individuals without identified trigger)
Study: NCT00012714

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Case management services
Study: NCT05291871

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HPV vaccine
Description: One-fifth dose bivalent HPV Vaccine or One-fifth dose nonavalent HPV Vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HPV vaccine
Description: One-fifth dose bivalent HPV Vaccine or One-fifth dose nonavalent HPV Vaccine
Study: NCT05239780

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Brain stimulation
Description: Brain stimulation will be performed after collection of clinical seizure data. Bipolar stimulation to one or several adjacent electrodes will be applied. Stimulation design will be either determined prior to testing or designed according to results from neurobehavioral assessments. Stimulation will consist of biphasic, constant-current trains of stimulation pulses at 100 Hz, with 100 ms pulse width or a sinusoidal wave of a predefined mean band frequency (i.e. 6Hz for θ, 11Hz for α, 20Hz for β, etc.). Stimulation intensity will be ≤6 mA, consistent with parameters used for clinical mapping, for the duration of the behavioral task or for short (2-3 s) periods of time at given epochs during the task (i.e. outcome evaluation). Clinical personnel will be available during stimulation to help monitor stimulation-induced after-discharges; if any are detected, stimulation intensity will be dialed down or terminated.
Study: NCT06456996

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Multi-component intervention package
Description: 1. Community-based spirometry pulmonary function tests and result interpretations and health education for COPD;~2. A digital health intervention program, NicQuit, for smokers(very familiar with intelligent mobile phone);~3. A digital health intervention program, EmoEase, for individuals whose WEMWBS questionnaire score is lower than 45(very familiar with intelligent mobile phone);~4. Health education to smokers for smoking cessation;~5. Health education to individuals with mental health issues;~6. Encouragement to seek professional medication treatment in superior hospitals for spirometry-defined COPD patients;~7. To actively include individuals whose blood pressurei s higher than 140/90 mmHg or/and whose random blood glucose higher than 11.1 mmol/L into the National Essential Public Health Service in China;~8. A CBT-based health education to the BMI abnormal, i.e., BMI \> 24.0 or BMI \< 18.5;~9. Pay-for-population mechanism for medical practitioners.
Study: NCT06411314

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Natamycin + Lactulose 100 mg + 300 mg vaginal suppositories
Description: 1 suppository once daily at bedtime for 6 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactulose 300 mg vaginal suppositories
Description: 1 suppository once daily at bedtime for 6 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pimafucin® (natamycin) 100 mg vaginal suppositories
Description: 1 suppository once daily at bedtime for 6 days
Study: NCT05840757

Intervention type: DEVICE
Group type: OTHER
Intervention: HemoSphere ClearSight Module
Description: The Clear Sight system consists of a finger cuff connected to a monitor It will be applied to the patients finger before and removed after the TAVI procedure.
Study: NCT05955781

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spinal Mobilization With Leg Movement
Description: spinal mobilization with leg movement is the intervention given to experimental group. This technique involves applying pressure to the relevant spinous process while the patient moves their limb through the previously restricted range of motion. It is assumed that the restriction of movement is due to a spinal issue but it does not always indicate nerve damage as spinal movement is necessary for limb movement beyond a certain point. The goal is to address any spinal mechanical limitations and there may also be potential effects on the nerves.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Spinal Mobilization
Description: The patients will be given Spinal mobilization transverse glide(kaltenborn glide) on the effected spinous process. The total time duration will be 25-30 minutes.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional treatment
Description: Participants will be given Hot pack for 15 minutes, TENS for 10 minutes

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Participants will be given Hot pack for 15 minutes, TENS for 10 minutes
Study: NCT05114252

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vivid Vision Home
Description: The study intervention consists of playing serious games (Vivid Vision, San Francisco, USA) embedded in a virtual reality headset in a home environment 5 days a week for 30 minutes over 8 weeks (20 h of total gaming).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vivid Vision Home
Description: The study intervention consists of playing serious games (Vivid Vision, San Francisco, USA) embedded in a virtual reality headset in a home environment 5 days a week for 30 minutes over 8 weeks (20 h of total gaming).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Refractive error correction
Description: The control intervention will be refractive error correction that consists of wearing the lenses with the prescribed correction for 2 months.
Study: NCT05446064

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stigma-reduction intervention
Description: The intervention is modularized into four weekly 1-hour group sessions, led by a trained facilitator who provides psychoeducation to promote awareness and understanding of HIV stigma and teach CBT-based coping skills. Each group session will last 45-60 minutes. Participants are introduced to the general CBT model of HIV stigma and encouraged to track thoughts, feelings, and behavioral responses when encountering external stigma or adverse events. The participants further learn to differentiate effective and ineffective coping strategies and practice applying new coping skills to reduce internalized HIV stigma. The interventionist will follow the intervention manual to deliver the intervention and assign homework for group members to practice on their own. In the following sessions, the interventionist will review progress with participants, guide participants through exercises, and identify additional problems to be addressed in subsequent sessions.