Study: NCT05023343

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine
Description: 30 mL Ropivacaine 0,75% administered as a unilateral TQL block

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quadriceps muscle strength
Description: Quadriceps muscle strength is assessed using a hand-held dynamometer. Each participant is tested pre block administration and 60 minutes after

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Quadriceps muscle strength
Description: Quadriceps muscle strength is assessed using a hand-held dynamometer. Each participant is tested pre block administration and 60 minutes after

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Timed Up and Go
Description: To test mobilisation the standardised Timed Up and Go test is used. Each participant is tested pre block administration and 60 minutes after

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Timed Up and Go
Description: To test mobilisation the standardised Timed Up and Go test is used. Each participant is tested pre block administration and 60 minutes after

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Single-leg 6 meter timed hop test
Description: To test muscle strength and power the single-leg 6 meter jump test is used. Each participant is tested pre block administration and 60 minutes after

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Single-leg 6 meter timed hop test
Description: To test muscle strength and power the single-leg 6 meter jump test is used. Each participant is tested pre block administration and 60 minutes after

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Temperature discrimination
Description: Dermatomal evaluation of cold and warm discrimination of the thoracic and lumbar dermatomes Approximately 60 minutes after block administration

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Temperature discrimination
Description: Dermatomal evaluation of cold and warm discrimination of the thoracic and lumbar dermatomes Approximately 60 minutes after block administration

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pinprick test
Description: Dermatomal evaluation of pinprick/sharp sensation of the thoracic and lumbar dermatomes.~Approximately 60 minutes after block administration

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Pinprick test
Description: Dermatomal evaluation of pinprick/sharp sensation of the thoracic and lumbar dermatomes.~Approximately 60 minutes after block administration

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Blood samples
Description: As a substudy the maximum serum concentration of ropivacaine is analyzed. Blood samples are taken at 0, 15, 30, 45 and 60 minutes after block administration

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Blood samples
Description: As a substudy the maximum serum concentration of ropivacaine is analyzed. Blood samples are taken at 0, 15, 30, 45 and 60 minutes after block administration

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Non-invasive blood pressure measurement
Description: Non-invasive blood pressure is measured prior to block administration and 30 minutes after block administration

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Non-invasive blood pressure measurement
Description: Non-invasive blood pressure is measured prior to block administration and 30 minutes after block administration