TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03909503

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Porcine-derived collagen wound dressing
Description: Patients who meet the inclusion criteria will be treated with porcine-derived collagen dressings. The dressing will be used in accordance with its label. After cleansing the wound, the dressing will be placed on the wound. Appropriate primary and secondary dressings will be placed over the intervention product. Patients will visit the clinic once per week to have their dressings re-applied. Wound evaluations will take place once per week with the intervention lasting up to twelve weeks. Concomitant standard of care such as compression for venous ulcers will be provided according to individual patient needs.
Study: NCT05647213

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: iPSC-CL
Description: Autologous IPSCL
Study: NCT05854134

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Closed Chain
Description: Effectiveness of Closed Chain for Strengthening and Improving Quality of Life in Post Stroke Patients

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Aerobic Exercise
Description: Effectiveness of Aerobic Exercise for Strengthening and Improving Quality of Life in Post Stroke Patients
Study: NCT06265896

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesio taping
Description: Tape will be applied on rectus abdominis muscles using muscles facilitation technique from origin to insertion of muscle with a tension between 15-35%. Band will start on symphysis pubis with no tension and then women make stretch on the abdominal region by deep abdominal inspiration and will end at xiphoid process. Tape will be applied on the right and left external oblique muscles; the procedure will start without tension from bottom and of 6-12 ribs, then the hip will be placed in flexion and rotation to opposite direction and the tape will be attached to pubic bone with tension between 15-35%. Finally, the tape will be performed on the right and left internal oblique muscles; the procedure will start without tension from anterior superior iliac spine and then the hip will be placed in extension position and the tape will be attached to lower 4 ribs and linea alba with tension between 15-35%.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic floor exercise training
Description: The intervention will be applied by a trained physical therapist. First of all, each participant will be instructed to relax thighs, bottom and abdomen musculature, then squeeze pelvic floor muscles 'focus on tightening without flexing abdomen, thighs or buttocks- avoid holding breath' 10 repetitions, 3 to 5 times a day (morning, afternoon, and night). Rest for 4 seconds and then repeat each contraction. Build up pelvic floor musculatures strength until each participant be able to do 10 slow contractions each time, holding them for 10 seconds each with rests of 4 seconds in between. Then do not hold your breath or tighten your stomach, bottom or thigh muscles at the same time. Will instruct participants to try holding each squeeze for a few seconds.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor exercise training
Description: The intervention will be applied by a trained physical therapist. First of all, each participant will be instructed to relax thighs, bottom and abdomen musculature, then squeeze pelvic floor muscles 'focus on tightening without flexing abdomen, thighs or buttocks- avoid holding breath' 10 repetitions, 3 to 5 times a day (morning, afternoon, and night). Rest for 4 seconds and then repeat each contraction. Build up pelvic floor musculatures strength until each participant be able to do 10 slow contractions each time, holding them for 10 seconds each with rests of 4 seconds in between. Then do not hold your breath or tighten your stomach, bottom or thigh muscles at the same time. Will instruct participants to try holding each squeeze for a few seconds.
Study: NCT06346912

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD19-BAFF Targeted CAR T-cells
Description: Each subject receive CD19-BAFF Targeted CAR T-cells by intravenous infusion
Study: NCT06334835

Intervention type: DIAGNOSTIC_TEST
Intervention: lncRNA signature analyses
Description: Evaluation of a signature of identified lncRNA in a cohort of childhood T-ALL patients in comparison with healthy subjects.

Intervention type: DIAGNOSTIC_TEST
Intervention: lncRNA signature analyses
Description: Evaluation of a signature of identified lncRNA in a cohort of childhood T-ALL patients in comparison with healthy subjects.
Study: NCT05057624

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo GC-MRT
Description: Participants will hear music continuously throughout the trials, without regard to the faces they look at.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: GC-MRT
Description: Participants will hear music as a reward for looking at neutral faces and the music will stop when they focus on angry faces.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure
Description: Participants will hear music of their choice when they focus on angry faces, and when they look at neutral faces the music will stop.
Study: NCT06177613

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blank culture transfer
Description: A maximum of 0.1 ml of gassed embryo culture medium preheated to 37°C is injected into the uterine cavity transcervically using an embryo transfer catheter placed just beyond the internal os, two to 3 days before transfer of the thawed embryo

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham transfer
Description: An intermediate transfer step is added two or three days before the planned transfer of the frozen embryo but with an empty catheter.
Study: NCT06016621

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Improvisational Music Therapy
Description: The therapist engages with the child by playing and sharing musical instruments, and/or sings while being attuned to the child's behaviour and expression. Various improvisational techniques are employed to engage the child. There are opportunities for pulse, rhythmic, dynamic or melodic patterns, and timbre to be mirrored, reinforced, or complemented, which allows for moments of synchronization between the therapist and the child, giving the child's musical expressions a pragmatic meaning within this context. The therapist may also gently provoke the child by violating expectations or patterns that have been jointly developed in order to elicit specific social communication behaviours. Further, there are opportunities for the child to develop and enhance social communication skills such as joint attention, sharing affect, reciprocity, shared history, scaffolding, imitation and turn-taking. These have been shown to develop social competency and also resilience.
Study: NCT05065021

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: Niraparib works by blocking poly(ADP-ribose) polymerases (PARP) 1 and PARP 2 from working. PARP 1 and PARP 2 are proteins that are involved in cell growth, cell survival, and cell death, including cancer cells. It is believed that blocking PARP1 and PARP 2 from working will slow or stop the growth of cancer cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: Niraparib works by blocking poly(ADP-ribose) polymerases (PARP) 1 and PARP 2 from working. PARP 1 and PARP 2 are proteins that are involved in cell growth, cell survival, and cell death, including cancer cells. It is believed that blocking PARP1 and PARP 2 from working will slow or stop the growth of cancer cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: Dostarlimab is a monoclonal antibody. Antibodies are proteins that are naturally found in the blood stream that fight infections. A monoclonal antibody is a special kind of antibody that is created in a laboratory that seeks out specific proteins in the body that may be involved in cancers to stop tumor growth. Dostarlimab attaches to PD-1 and inhibits the interaction of PD-L1 and PD-L2 with PD-1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: Dostarlimab is a monoclonal antibody. Antibodies are proteins that are naturally found in the blood stream that fight infections. A monoclonal antibody is a special kind of antibody that is created in a laboratory that seeks out specific proteins in the body that may be involved in cancers to stop tumor growth. Dostarlimab attaches to PD-1 and inhibits the interaction of PD-L1 and PD-L2 with PD-1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab is a chemotherapy drug commonly used for the treatment of various cancers.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab is a chemotherapy drug commonly used for the treatment of various cancers.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab is a chemotherapy drug commonly used for the treatment of various cancers.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a chemotherapy drug commonly used for the treatment of various cancers.
Study: NCT06231108

Intervention type: OTHER
Intervention: Kinesio Taping
Description: Three different taping applications will be applied, namely ankle correction, quadriceps facilitation, and gluteus maximus facilitation.~1. Taping: Functional correction technique will be used to facilitate dorsal flexion movement.~2. Taping: Quadriceps Femoris (QF) Facilitation Technique - In taping to activate the QF muscle and regulate muscle tone, the patient will be placed in a supine position with hips and knees in neutral.~3. Taping: Gluteus Maximus (GM) Facilitation Technique - For taping to facilitate the GM muscle, a double-band application will be performed.
Study: NCT06080750

Intervention type: GENETIC
Intervention: Quantitative Real Time Polymerase chain reaction (qRT-PCR)
Description: to study gene expression of NLRP3 inflammasome and IL-1B in blood

Intervention type: GENETIC
Intervention: Quantitative Real Time Polymerase chain reaction (qRT-PCR)
Description: to study gene expression of NLRP3 inflammasome and IL-1B in blood

Intervention type: GENETIC
Intervention: Quantitative Real Time Polymerase chain reaction (qRT-PCR)
Description: to study gene expression of NLRP3 inflammasome and IL-1B in blood

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA and colorimeter
Description: IL-6 and total LDH

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA and colorimeter
Description: IL-6 and total LDH

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA and colorimeter
Description: IL-6 and total LDH
Study: NCT06510335

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lavender essential oil-based product system
Description: Participants used the study products in a sequential, additive manner approximately 30-60 minutes before bedtime each night for 6 weeks. Usage consists of the following:~* 20 drops of essential oil blend in approximately 250 mL of water in a diffuser, which operated for 8 hours at nighttime.~* 3 x 6 swipes of the topical stick on the upper chest area, and 2 x 3 swipes on the inside of each wrist for topical application.~* 2 capsules of the dietary supplement.~Participants used the essential oil blend alone for 1 week, then added the topical stick for another 1 week. Finally, participants used the essential oil blend, the topical stick, and the dietary supplement for four weeks.
Study: NCT05027269

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AOC 1001
Description: AOC 1001 will be administered by intravenous (IV) infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AOC 1001
Description: AOC 1001 will be administered by intravenous (IV) infusion.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered by intravenous (IV) infusion.
Study: NCT06737471

Intervention type: OTHER
Intervention: Extensive rehabilitation treatment
Description: A 3-hour weekly rehabilitation treatment will be delivered to each patient for 15 weeks (45 hours) in an outpatient setting.~Rehabilitation will address the following macro goals: gross motor, manipulative, visual and visual-cognitive.
Study: NCT06737029

Intervention type: DIAGNOSTIC_TEST
Intervention: Enhanced diagnostic workup
Description: Patients will undergo review by a study physician, including a detailed history and physical examination, as well as review of additional investigations that have been performed thus far.~Based on the precise nature of the complaints, and additional findings, additional diagnostic testing may be requested, including, but not limited to: blood testing, spirometry, computed tomography of the chest, repeat chest X-ray, sputum investigations, or bronchoscopy.
Study: NCT05027269

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered by intravenous (IV) infusion.
Study: NCT06498908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitrous oxide
Description: Nitrous oxide, commonly known as laughing gas, is a colorless, non-flammable gas with a slightly sweet odor, used for its analgesic and anesthetic properties in medical and dental procedures to provide pain relief and sedation.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxygen
Description: Oxygen is a colorless, odorless gas essential for human respiration and used medically to treat conditions resulting from low oxygen levels in the blood. In this trial Oxygen is being used as a placebo.
Study: NCT05477771

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthroscopic rotator cuff repair
Description: The rotator cuff tears were repaired under arthroscopy. A subacromial decompression was performed in all patients. Then the long head of the biceps with severe lesions were treated by tenotomy while the others were reserved according to the surgeon's judgment during the surgery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthroscopic rotator cuff repair
Description: The rotator cuff tears were repaired under arthroscopy. A subacromial decompression was performed in all patients. Then the long head of the biceps with severe lesions were treated by tenotomy while the others were reserved according to the surgeon's judgment during the surgery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthroscopic rotator cuff repair
Description: The rotator cuff tears were repaired under arthroscopy. A subacromial decompression was performed in all patients. Then the long head of the biceps with severe lesions were treated by tenotomy while the others were reserved according to the surgeon's judgment during the surgery.
Study: NCT06102161

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wedge resection
Description: Wedge resection is a surgical procedure that is done to remove a wedge-shaped section of lung tissue, usually for treating lung cancer. A wedge resection is less invasive than some of the other surgical options used to remove lung cancer.
Study: NCT05839132

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: 20 minutes of acupuncture treatment, twice a week for 2 weeks. Acupoints will be manually stimulated every 10 minutes.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Acupuncture
Description: 20 minutes of acupuncture treatment, twice a week for 2 weeks. Acupoints will be manually stimulated every 10 minutes.
Study: NCT05881850

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49. The research is carry out as a randomized controlled experimental in a pretest-posttest design.
Description: The education program consisting of three sessions was held once a week and each session lasted approximately 40-50 minutes. In the realization of the education program, a power point presentation consisting of the contents of the education booklet prepared for Osteoporosis awareness, a three-dimensional bone model with Osteoporosis and normal bone tissue, some food samples containing calcium during nutrition education, and measuring cups to show portions and amounts were used. During the training, a question and answer activity was also held. The education booklet was also given to the intervention group at the end of the first session.
Study: NCT05293938

Intervention type: DRUG
Intervention: Obeticholic Acid 5 MG
Description: once daily, oral administration

Intervention type: DRUG
Intervention: Obeticholic Acid 10 MG
Description: once daily, oral administration

Intervention type: DRUG
Intervention: Standard of Care: UDCA
Description: No study medication is provided by the sponsor or by the investigators. The decision to initiate, continue or discontinue UDCA, or to modify UDCA dosing, is entirely at the discretion of the treating physician as per their standard of care and is in no way influenced by the sponsor or participating institutions. UDCA utilization is recorded and included in the study record.
Study: NCT05712382

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.
Study: NCT05076708

Intervention type: OTHER
Group type: OTHER
Intervention: IQOS
Description: All participants switch from cigarette smoking to IQOS use for a 14-day phase.
Study: NCT05712382

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent handbook
Description: Handbook motivating parents to discuss alcohol use with their college student.
Study: NCT03606746

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MDR-103
Description: MDR-103 Enriched CD34+ hematopoietic stem cells and defined dose of CD3+ T-cells
Study: NCT04520698

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: UPLIFT-AD
Description: Access to palliative care needs screening, advance care planning conversations, palliative care consultations
Study: NCT06346275

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupoints: Baihui (GV20), Sishencong (EX-HN1), Fengchi (GB20), Taixi (KI3), Zusanli (ST36), Sanyinjiao (SP6), Neiguan (PC6), and Shenmen (HT7).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture
Description: Acupoints: Baihui (GV20), Sishencong (EX-HN1), Fengchi (GB20), Taixi (KI3), Zusanli (ST36), Sanyinjiao (SP6), Neiguan (PC6), and Shenmen (HT7).
Study: NCT06023914

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STRENGTH EVALUATION WITH ELECTROSTIMULATOR
Description: Evaluation of isometric strength using an electrostimulator.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: STRENGTH EVALUATION WITHOUT ELECTROSTIMULATOR
Description: Evaluation of isometric strength not using an electrostimulator.
Study: NCT06104683

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirtobrutinib
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirtobrutinib
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirtobrutinib
Description: Administered orally
Study: NCT05946330

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: NUTRITIONAL EDUCATIONAL INTERVENTION IN FATTY LIVER DISEASE NON-ALCOHOLIC (NAFLD).
Description: The intervention group will receive educational actions in individual nutrition with nutrition consultation (in person at the beginning and at 180 days of the intervention and phone calls and text messages at 30, 60, 90, 120 and 150, 240 and 300 days of follow-up

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NUTRITIONAL EDUCATIONAL INTERVENTION IN FATTY LIVER DISEASE NON-ALCOHOLIC (NAFLD).
Description: The intervention group will receive educational actions in individual nutrition with nutrition consultation (in person at the beginning and at 180 days of the intervention and phone calls and text messages at 30, 60, 90, 120 and 150, 240 and 300 days of follow-up
Study: NCT05568745

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Balloon for cervical ripening (Teleflex French Dufour catheter CH20 reference 174000)
Description: Balloon catheter is inserted by a resident or a physician under visual control. The expected volume injected in the balloon probe is 60 mL. No traction is performed on the catheter. The catheter is left in place for a maximum of 12 hours.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Intravenous oxytocin addition (preceded or followed by epidural analgesia on patient's request) will be performed 6 hours after insertion of balloon catheter. Oxytocin is administered as an intravenous infusion (5 IU of oxytocin in 49 mL of 5% glucose\*) at the lowest possible dose with the aim of achieving a maximum of three to four contractions per ten minutes. After appropriate uterine activity has been achieved, the rate of the oxytocin infusion is decreased or stopped.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Misoprostol Oral Tablet
Description: Patients will receive misoprostol 25 micrograms given orally (oral prostaglandin E1). The same dose will be given every 2 hours until beginning of labor with a maximum of 8 administrations.
Study: NCT05778318

Intervention type: DRUG
Intervention: The group of patients who received Lianhua Qingwen orally
Description: Lianhua Qingwen Granules: oral. One bag at a time, three times a day. The course of treatment for mild and ordinary cases of novel coronavirus pneumonia is 7-10 days.

Intervention type: OTHER
Intervention: The group of patients who did not receive Lianhua Qingwen orally
Description: The group of patients who did not receive Lianhua Qingwen orally.