TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05973448

Intervention type: OTHER
Group type: OTHER
Intervention: Control Lighting Condition
Description: Standard night light plugged into wall socket

Intervention type: OTHER
Group type: OTHER
Intervention: Control Lighting Condition
Description: Standard night light plugged into wall socket
Study: NCT05464056

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Be Unstoppable in Life Together (BUILT)
Description: Participants will complete weekly sleep, food, and exercise home challenges focused on creating sustainable healthy eating, sleep, and exercise routines. Parents will participate in weekly support calls by UIC and Chicago Park District staff to provide support and accountability. Children will have the opportunity to win small prizes based on completing weekly challenges. The intervention will be co-facilitated by UIC students and Chicago Park District staff and will largely take place on-line. For additional details visit: https://built.ahs.uic.edu.
Study: NCT05816070

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IVIEW-1201
Description: Four times per day for day 1-2 and three times per day for day 3-7

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ofloxacin Eye Drops
Description: Four times per day for day 1-2 and three times per day for day 3-7
Study: NCT05943457

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin K2 or menaquinone-7
Description: Vitamin K2 (MK7) 360 mcg/day orally once daily for 6 months

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo pills will be administered orally once daily for 6 months
Study: NCT04766268

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prostate artery embolization
Description: Prostate artery embolization (PAE) is a safe and effective minimally invasive interventional radiology procedure in which intraprostatic vessels are embolized to shrink the size of the prostate gland. LUTS is mainly categorized into irritative, obstructive, and mixed types. This has a variable impact on patients' quality of life by interfering with sleep, activities of daily living, anxiety, mobility, leisure, and effect on sexual activities. This trial aims to determine safety and effectiveness of prostate artery embolization and determine factors associated with improved procedure outcome.
Study: NCT04515459

Intervention type: OTHER
Group type: OTHER
Intervention: Surgical prehabilitation program.
Description: This programme will include the practice of general physical activity and the implementation of nutritional and psychological support.~Each patient will have 8 Oncorehabilitation Transdisciplinary Evaluations (OTE):~* 2 OTE will be performed before the surgery,~* 6 OTE will be performed after the surgery.~During the program (at each OTE), patients will also be asked to complete the QLQ-C30 questionnaire.
Study: NCT04813627

Intervention type: PROCEDURE
Intervention: Regular blood sample collection for ctDNA assessment
Description: Blood samples for in vitro testing of ctDNA status will be drawn at study visits every three months
Study: NCT05098093

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: SBE
Description: Hard-shell capsule

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: DBE
Description: Hard-shell capsule

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: BP
Description: Hard-shell capsule
Study: NCT05276466

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Polymerase Chain Reaction and Next-Generation DNA Sequencing
Description: The qPCR Rapid Screening Panel is a quantitative real-time PCR test for bacteria and fungi.~Next-Generation DNA Sequencing is the Comprehensive Sequencing test will detect virtually all microbial organisms and fungal pathogens that may be present in patient specimens.
Study: NCT04586699

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medi1TMS
Description: rTMS theta-burst protocol paired with a consistent attention-to-breath task
Study: NCT05841979

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moodlifters
Description: Mood Lifters, a novel mental wellness program, was developed as a more accessible means to provide psychotherapy (Votta \& Deldin, 2022). Meetings covered biopsychosocial areas and skills that were drawn from multiple therapeutic interventions consistent with a biopsychosocial framework. Areas included physical health, negative thoughts, problem-solving, emotional awareness and regulation, building relationships, behavioral activation, and using a strengths-based approach. ML is delivered by peer leaders who are individuals that have completed the program as well as a training program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Participants randomized to the exercise arm received 14 weeks of a structured weekly strength and conditioning training program to enhance muscle mass, strength, cardiorespiratory fitness, and overall well-being. The program is based on previous research showing that cardiorespiratory fitness and muscle strength/size can both contribute to decreased mortality/increased longevity and enhanced mental health (Burke et al., 2017; McLeod et al., 2016; Srikanthan \& Karlamangla, 2014; Strasser \& Burtscher, 2018). The training program consists of three training sessions per week, with one being an in-person group session guided by a certified strength and conditioning specialist. The other two training sessions are self-guided via the mobile app Trainheroic. This weekly training schedule aligns with previous research showing benefits to structuring an exercise program using a variety of social contexts (group setting, own, etc.; Burke et al., 2017).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nature Experiences
Description: Participants randomized to the Nature Experiences participated in 14 weeks of group and self-directed activities to connect with the natural environment. Weekly group activities will be led by Nature Guides, who are undergraduate and graduate students with extensive outdoor education training. Group activities will last one hour a week and include hiking in forests, walking in parks, bird-watching, mindfulness exercises, and snow activities. Participants will be given a list of self-directed activity suggestions each week. The goal of self-directed activities is to spend an additional two hours in a natural environment each week.
Study: NCT04844580

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inhaled Aviptadil
Description: Aviptadil is the synthetic analogue of the Vasoactive Intestinal Peptide (VIP), a biologically active 28 amino acid natural peptide that is endogenously synthesized in humans. It is one of the signaling molecules of the neuroendocrine immune network and has vasodilator, anti-proliferative, anti-inflammatory and immunomodulatory properties.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Aviptadil Placebo will be used for this arm.
Study: NCT04586699

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medi2TMS
Description: rTMS theta-burst protocol paired with an intermittent deep breathing task
Study: NCT06048770

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RBI-4000
Description: RBI-4000 intramuscular injection.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RBI-4000
Description: RBI-4000 intramuscular injection.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RBI-4000
Description: RBI-4000 intramuscular injection.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RBI-4000
Description: RBI-4000 intramuscular injection.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: RabAvert
Description: RabAvert intramuscular injection.
Study: NCT05061238

Intervention type: DEVICE
Group type: OTHER
Intervention: Vibrating Device
Description: The vibrating device strapped to different parts of your leg. The device will be secured to your leg with a Velcro strap.
Study: NCT06578286

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARX788
Description: ARX788，1.5 mg/kg IV infusion on Day 1 of each 21-day treatment cycle
Study: NCT05855330

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Arginine Hydrochloride
Description: Arginine will be infused based on the manufacturer's instructions (R-Gene 10, Pfizer), over 30 minutes. However, rates may be slowed to over 60 minutes for patients experiencing symptoms of flushing, nausea, vomiting, or headache at the research team's discretion. Pediatric doses will be drawn up by the pharmacy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Arginine Hydrochloride
Description: Arginine will be infused based on the manufacturer's instructions (R-Gene 10, Pfizer), over 30 minutes. However, rates may be slowed to over 60 minutes for patients experiencing symptoms of flushing, nausea, vomiting, or headache at the research team's discretion. Pediatric doses will be drawn up by the pharmacy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Arginine Hydrochloride
Description: Arginine will be infused based on the manufacturer's instructions (R-Gene 10, Pfizer), over 30 minutes. However, rates may be slowed to over 60 minutes for patients experiencing symptoms of flushing, nausea, vomiting, or headache at the research team's discretion. Pediatric doses will be drawn up by the pharmacy.
Study: NCT05525273

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral dabrafenib and trametinib
Description: Neoadjuvant or postoperative treatment of patients with verified BRAF mutated papillary craniopharyngioma
Study: NCT05944965

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atomoxetine 80 mg plus Oxybutynin 5 mg
Description: 80mg Atomoxetine and 5mg Oxybutynin administered 30mins prior to bed

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atomoxetine 80 MG
Description: 80mg Atomoxetine administered 30 mins prior to bed

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo and placebo (sugar pill) administered 30 mins prior to bed
Study: NCT05934968

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mad Dog cooking class series
Description: This 6-week series consists of a once-weekly cooking class and educational session where a group of individuals with neuromuscular disability can come together to learn about the health benefits of an anti-inflammatory diet, receive instruction on how to cook selected anti-inflammatory recipes, and experiment with various pieces of accessible kitchen equipment that may increase their meal preparation skills. This series will also allow participants to share a meal together once per week.
Study: NCT05189366

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sophrology
Description: Sophrology is a relaxation method that's sometimes referred to as hypnosis, psychotherapy, or a complementary therapy.~Sophrology uses techniques such as: hypnosis, visualization, meditation, mindfulness, breathing exercises, gentle movements, body awareness...~Sophrology techniques may be useful during medical procedures that cause stress and discomfort.~Sophrology techniques may be useful during medical procedures that cause stress and discomfort.~Patients will receive 6 sessions of sophrology

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Speech therapy
Description: Speech therapy is a treatment that can help improve communication skills. patients will benefit from two speech therapy sessions per week for 6 months, lasting from 30 minutes to 1 hour depending on the patient's general condition.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Speech therapy
Description: Speech therapy is a treatment that can help improve communication skills. patients will benefit from two speech therapy sessions per week for 6 months, lasting from 30 minutes to 1 hour depending on the patient's general condition.
Study: NCT05563194

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Heating prototype (Prototype 1)
Description: A wearable that heats and vibrates to help distract from pain. It can be wrapped around any joint with temperature and vibration settings allowing CYP to set the device to their needs.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Physio tool (Prototype 2)
Description: A motivational physiotherapy tool that incrementally lights up as the CYP do their prescribed stretches, emphasising a sense of progression and making it a more engaging activity.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Communication tool (Prototype 3)
Description: A wearable to help communication in the classroom between the teacher and pupil. The child can alert the teacher if they need help, through vibration, without attracting the attention of their classmates, reducing embarrassment.
Study: NCT05238493

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEL-101
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intervention administered via subcutaneous injection or 1-hour intravenous infusion on Day 1
Study: NCT06074120

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-level laser therapy
Description: Low-level laser therapy would be introduced via a vaginal probe (gain medium: Gallium-Aluminum-Arsenide, wavelength 660nm) for 30 minutes per treatment, once a week, for 8 courses.
Study: NCT04480411

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Doctorgram Patient Kit
Description: Participants will use the Doctorgram Patient Kit for remote monitoring and remote use stethoscope.
Study: NCT04725344

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ACTIV'DOS group
Description: ACTIV'DOS group use ACTIV'DOS application (with smartphone) to do the self rehabilitation each day (15 minutes per day) during 6 weeks. There are 7 exercices.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual practise
Description: Control group uses a standard sheet of paper to do the self-rehabilitation (15 minutes per day) during 6 weeks. There are 7 exercises.
Study: NCT06015633

Intervention type: OTHER
Intervention: No intervention
Description: Observational only

Intervention type: OTHER
Intervention: No intervention
Description: Observational only
Study: NCT05322941

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AEF0117
Description: AEF0117 (1.0, 0.3, and 0.1 mg) capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral capsule
Description: Corn oil capsule manufactured to mimic AEF0117 capsule
Study: NCT05461001

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Warm Up Exercises
Description: The daily warm up exercises for male football players include full body stretch, high knees, lunges, squat and burpees.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Endurance Based Exercises
Description: Sport-specific endurance-running (duration \[in minutes\], total distance \[in meters\], mean speed \[in meters per minute\], high-speed running \>15 km·h-1, and relative high-speed running \[\>75% and \>85% of maximal velocity\]) will be given to the experimental group. Athletes will run in excess of 15 km of total distance (TD) and 4 km of high-speed (\>15 km·h-1) distance per session 3 to 4 running-based endurance sessions per week for 6 weeks.
Study: NCT05259462

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Participants will utilize low-cost, consumer available head-mounted displays to meet with peers and coaches online. The program will last 4 weeks and include 2 x 1-hour sessions per week of supervised peer-to-peer gaming. The coaches will utilize behavioral change and mindfulness techniques to promote autonomy, competence, and relatedness through a respectful, cohesive, and positive atmosphere. These strategies will be framed by the Self-Determination Theory and learned from the National Center on Health, Physical Activity, and Disability (NCHPAD) mindfulness coaching workshops. Some of the mindfulness-based strategies will include guided breathing focused exercises, body scanning, meditation, and acceptance of social anxiety and shyness
Study: NCT06234410

Intervention type: RADIATION
Intervention: Computed tomography coronary angiography (CTCA)
Description: Single CTCA scan prior to kidney transplantation
Study: NCT05288426

Intervention type: OTHER
Intervention: No intervention
Description: This is an observational study, with no intervention.

Intervention type: OTHER
Intervention: No intervention
Description: This is an observational study, with no intervention.

Intervention type: OTHER
Intervention: No intervention
Description: This is an observational study, with no intervention.

Intervention type: OTHER
Intervention: No intervention
Description: This is an observational study, with no intervention.
Study: NCT04076410

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Z1 lens
Description: CE marked device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental Lens 1
Description: CE marked device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental Lens 2
Description: CE marked device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental Lens 3
Description: CE marked device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental Lens 4
Description: CE marked device
Study: NCT05548101

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ICSI
Description: Using the injecting pipet, one sperm will be isolated. Using the tip of the injecting pipet, the sperm tail will be broken by trapping it between the pipet and bottom of the dish. The sperm will be picked up in the pipet. The oocyte will be positioned so the polar body is at the 12 o'clock or 6 o'clock position. The sperm injecting pipet will be positioned at the 3 o'clock position of the oocyte. The injecting pipet will be advanced into the oocyte cytoplasm and the cytoplasm will be gently aspirated until the oocyte membrane breaks. The sperm will then be injected into the cytoplasm of the oocyte. The pipet will then be withdrawn from the oocyte.
Study: NCT06492824

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enjoyable Activities Condition
Description: Participants complete an introduction video about the intervention. They will then take a pre-intervention survey, after which they will choose five enjoyable activities from a large list. Daily text message reminders will be sent to BA participants in the morning to remind them to do their enjoyable activities for the day, as well as a link to a checklist where they will report how frequently they have completed any of their five activities from the previous day (example text message in documentation). At the end of the month, they will complete a follow-up survey consisting of the same measures from the pre-intervention survey.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Activities Condition
Description: They will take a pre-intervention survey and choose five enjoyable activities from the same list; however, active control participants will not explicitly be asked to complete these activities for the intervention. Participants in the active control condition will be promoted to complete tasks such as drinking more water, going to bed early, brushing their teeth, showering or bathing for that day, and eating well balanced meals. Daily text reminders will be sent about these healthy living activities in the morning. In that same message, they will receive a link to a checklist where they will report about their completed healthy living activities for the previous day (example text message in documentation). At the end of the month, they will also complete a follow-up survey consisting of the same measures from the pre-intervention survey.
Study: NCT06113848

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intra-Arterial TNK and Albumin
Description: The study population was divided into four groups, one of which had intra-arterial TNK and albumin.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intra-Arterial TNK
Description: The study population was divided into four groups, one of which had intra-arterial TNK .

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intra-Arterial Albumin
Description: The study population was divided into four groups, one of which had intra-arterial albumin.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: sham
Description: The study population was divided into four groups, one of which had no intra-arterial TNK and albumin.
Study: NCT06596642

Intervention type: DRUG
Intervention: Luspatercept
Description: As per product label
Study: NCT06111222

Intervention type: DEVICE
Group type: OTHER
Intervention: HECATE
Description: The device is CE-approved. The device is a posterior chamber multifocal intraocular lens (IOL) indicated for aphakia after surgical extraction of the cataractous natural lens. The device is also indicated for non-cataractous, presbyopic patients (PRELEX) who seek greater independence from glasses for intermediate and/or near distances. It is an aspheric (aberration-neutral) IOL made of hydrophobic acrylic material, coated with heparin with modified C-loop haptics.
Study: NCT06085430

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kubota Glass
Description: Kubota Glass employs white light producing micro-LEDs covered by masks which create a patterned target. The patterned images are defocused by micro-lenslets and projected to the retinal periphery by a central mirror. Parameters of interest to evaluate in this investigation include but are not limited to dioptric amount of defocus, brightness (cd/m2), spectrum of illumination, and shape of the target mask. In each scenario, right eyes will be exposed to the stimulus, whereas left eyes serve as controls. The order of exposures to the various stimuli will be randomized to participant and investigator.
Study: NCT05828979

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: UroMems artificial urinary sphincter
Description: Implantation of the device