TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05241795

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Knee then Ankle rehabilitation protocol
Description: Patients will start with knee exercise program that includes~* Partial Squats: The exercise will be performed as 3 sets of 10 repetitions each day.~* Toe Raises: The exercise will be performed as 3 sets of 10 repetitions each day.~* Stationary bike will be used (10-15 minutes /day) when the patients can bend their knees at least 100 degrees, as cycling is considered as an excellent conditioning and building exercise for the quadriceps muscles. As the patient's ability to pedal the bike with the operative leg improved, the therapist will increase the resistance.~* Hamstring exercises: After 6 weeks, the hamstring muscles will be exercised by the patient pulling the heel back producing a hamstring contraction.~Then, Patients will start ankle exercises program that includes:~* Standing calf raises~* Foot lift~* Ankle eversion exercises~* Ankle Plantarflexion exercises

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ankle then Knee rehabilitation protocol
Description: Patients will start ankle exercises program that includes:~* Standing calf raises~* Foot lift~* Ankle eversion exercises~* Ankle Plantarflexion exercises~Then, Patients will start with knee exercise program that includes~* Partial Squats: The exercise will be performed as 3 sets of 10 repetitions each day.~* Toe Raises: The exercise will be performed as 3 sets of 10 repetitions each day.~* Stationary bike will be used (10-15 minutes /day) when the patients can bend their knees at least 100 degrees, as cycling is considered as an excellent conditioning and building exercise for the quadriceps muscles. As the patient's ability to pedal the bike with the operative leg improved, the therapist will increase the resistance.~* Hamstring exercises: After 6 weeks, the hamstring muscles will be exercised by the patient pulling the heel back producing a hamstring contraction.
Study: NCT06630663

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A Wearable Device and AI-Supported Diet and Exercise intervention
Description: The standard dietary education encompasses instruction on the calculation of total caloric intake and emphasizes the principles of the Mediterranean diet. Tailored dietary concepts are developed based on individual patient habits to give practical advice. Each participant who chose an extra wearable device downloaded the APP to connect with the health management platform. User interface of the health management platform collected data on the number of steps walked, distance, and heart rate spontaneously. Participants recorded a dietary diary every day with a smartphone APP. All collected information was uploaded to the health management platform, too. The well-trained case managers offered a platform to coach the participants to set-up a better self-managed lifestyle modification through strategies of emphasize reminders, tracking / monitoring/ feedback and goals / rewards.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: standard care
Description: The standard dietary education encompasses instruction on the calculation of total caloric intake and emphasizes the principles of the Mediterranean diet. Tailored dietary concepts are developed based on individual patient habits to give practical advice. Each participant who chose an extra wearable device downloaded the APP to connect with the health management platform. User interface of the health management platform collected data on the number of steps walked, distance, and heart rate spontaneously. Participants recorded a dietary diary every day with a smartphone APP. All collected information was uploaded to the health management platform, too. The well-trained case managers offered a platform to coach the participants to set-up a better self-managed lifestyle modification through strategies of emphasize reminders, tracking / monitoring/ feedback and goals / rewards.
Study: NCT05120440

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breakfast omission
Description: Breakfast omission will consist of not eating breakfast on the morning of afternoon resistance training performance assessment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Breakfast consumption
Description: Breakfast consumption will consist of eating a standardized breakfast on the morning of afternoon resistance training performance assessment.
Study: NCT04751747

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT simulation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Contrast Agent
Description: Given IV
Study: NCT06277622

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PFUN
Description: perform preoperative preparation, intraoperative operation and internal fixation implantation according to the instructions provided in the product packaging.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PFNA
Description: perform preoperative preparation, intraoperative operation and internal fixation implantation according to the instructions provided in the product packaging.
Study: NCT06147830

Intervention type: OTHER
Intervention: None (Observational study)
Description: Not Applicable since Observational Study

Intervention type: OTHER
Intervention: None (Observational study)
Description: Not Applicable since Observational Study
Study: NCT06278857

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab-Gxly 50 MG/1 ML Intravenous Solution [JEMPERLI]
Description: The dosing regimen follows standard clinical care protocol comprising of 4 cycles every 3-weeks, a rest period of 34 weeks followed by 3 cycles every 6 weekly for a total of 7 cycles.
Study: NCT06434051

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Chinese cervical manipulation
Description: The CMP will first palpate the transverse processes of C1 and C2. The transverse process with apparent tenderness will be regarded as the pain side. The right side will be the painful side for the following example). During the manipulation, the CMP will use his left hand to support the lower jaw and passively rotate the neck to the left side by 70-75 degrees (or to the maximum angle without discomfort). The physician's right-hand fingers will support the left-side transverse processes of C1 and C2, and the thumb and thenar muscle will be placed on the spinous process and occipital area. While maintaining a passive left neck rotation, the physician will increase the rotation angle by 5-10 degrees with both hands under a sudden pulling force. The above procedure will be repeated on the right side (pain side).

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham manipulation
Description: The posture and position of the participant and the practitioner and the procedure are the same as the CCM technique. The right side will be regarded as the pain side once again. When performing the sham technique, the CMP uses the left hand to support the lower jaw position and passively rotates the neck to the left side by 70-75 degrees or to the maximum angle. The right hand presses the upper inner corner of the right scapula. While maintaining the passive left rotation of the neck, the right hand slowly exerts force downwards and outwards on the inner side of the scapula. The left hand only maintains the left rotation of the neck without any pulling force. After completion, repeat the above actions on the right side. After the technique is completed, participants can get up after resting for 5-10 minutes.
Study: NCT06423313

Intervention type: PROCEDURE
Intervention: maintenance of anesthesia
Description: Types used to maintain anesthesia

Intervention type: PROCEDURE
Intervention: maintenance of anesthesia
Description: Types used to maintain anesthesia
Study: NCT04732676

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Smartphone application
Description: Ecological Momentary Assessment (EMA)~: ambulatory assessment of behaviors/symptoms in real-time on smartphones

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Smartphone application
Description: Ecological Momentary Assessment (EMA)~: ambulatory assessment of behaviors/symptoms in real-time on smartphones
Study: NCT05091164

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Drug induce sleep endoscopy of upper aerodigestive tract under hypnosis
Description: Drug induce sleep endoscopy of upper aerodigestive tract under hypnosis.
Study: NCT06480656

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rehabilitation with eccentric cycling exercise
Description: Instead of normal cycling, patients will exercise on the eccentric bike.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: normal rehabilitation
Description: Normal rehabilitation will be conducted
Study: NCT05165290

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Latanoprost ophthalmic solution, 0.005%
Description: Commercially available, FDA-approved generic latanoprost ophthalmic solution, 0.005% (LAT) without modification will be used as the active control

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TC-002 latanoprost ophthalmic solution, 0.005%
Description: TC-002 is formulated using the commercially available latanoprost drug substance; delivered drop to the eye is preservative-free.
Study: NCT05275842

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Processing Therapy- Lifesteps (CPT-L)
Description: CPT-L is designed to help people with HIV and PTSD take their medications as prescribed. Cognitive Processing Therapy (CPT) uses education and cognitive training to help individuals identify thoughts and feelings about their trauma and gives them tools to help them change unhelpful beliefs. Lifesteps (L) includes education on the need for people with HIV to take their medications as prescribed and what could happen if you do not, as well as gives you tools to help motivate and remind you to take your medications on time.~Participants will receive a 12-session Cognitive Processing Therapy-Lifesteps (CPT-L) treatment program at the Ryan White clinic. The CPT-L program will be delivered twice a week for 6 weeks. Each session last about 90-minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifesteps
Description: Lifesteps (L) includes education on the need for people with HIV to take their medications as prescribed and what could happen if you do not, as well as gives you tools to help motivate and remind you to take your medications on time.~Participants will complete one Lifesteps education session. This session lasts about 60 minutes. Participants may attend this session either in-person or over the internet if they have an internet ready device with audio.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifesteps
Description: Lifesteps (L) includes education on the need for people with HIV to take their medications as prescribed and what could happen if you do not, as well as gives you tools to help motivate and remind you to take your medications on time.~Participants will complete one Lifesteps education session. This session lasts about 60 minutes. Participants may attend this session either in-person or over the internet if they have an internet ready device with audio.
Study: NCT05507281

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided Erector Spinae Plane Block
Description: ultrasound-guided ipsilateral Erector Spinae Plane Block (20 ml (19ml bupivacaine 0.25% plus 1ml dexamethasone 4mg)).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Retrolaminar Block
Description: ultrasound-guided ipsilateral Retrolaminar Block (20 ml (19ml bupivacaine 0.25% plus 1ml dexamethasone 4mg)).

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Control
Description: General anesthesia
Study: NCT06281821

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mhealth-pc
Description: Participants meet with an interventionist who explains the rationale for the mobile app. They complete video and survey-based intervention content each week for 8 weeks. App-based sessions are supplemented with brief chat-based coaching weekly.
Study: NCT06343285

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Encora Therapeutics Tremor Reduction Device
Description: The proposed therapeutic device uses vibration motors positioned around the wrist that provide on-demand-therapy to suppress resting, postural, or action tremors of the hand.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Encora Therapeutics Tremor Reduction Device
Description: The proposed therapeutic device uses vibration motors positioned around the wrist that provide on-demand-therapy to suppress resting, postural, or action tremors of the hand.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Encora Therapeutics Tremor Reduction Device
Description: The proposed therapeutic device uses vibration motors positioned around the wrist that provide on-demand-therapy to suppress resting, postural, or action tremors of the hand.
Study: NCT05550922

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthcare Transition-Based Education
Description: The goal is for asthmatic adolescents to take responsibility for their own disease, be prepared for transition to adult pulmonology services, increase their self-efficacy, and gain management skills as a result of health care transition education.
Study: NCT05709457

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cash transfer in prior study
Description: Women were offered a cash transfer conditional on attending prenatal and postnatal visits and delivering in a facility
Study: NCT05155579

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Licensed vaccine - Pneumococcal vaccine
Description: Licensed vaccine part of the EPI vaccination schedule

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Licensed vaccine - Inactivated Polio Vaccine (IPV)
Description: Licensed vaccine part of the EPI vaccination schedule

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Licensed vaccine - Inactivated Polio Vaccine (IPV)
Description: Licensed vaccine part of the EPI vaccination schedule
Study: NCT06337513

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation intervention
Description: The intervention consists of a physiotherapist-coordinated (PT) interdisciplinary outpatient rehabilitation offer for 6-months.~The intervention encompasses 3 individual sessions with the PT, if needed individual sessions with the interdisciplinary team (PT, occupational therapist, OT, nurse, and social worker) (a maximum of 6 hours), and patient education in two group seminars.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Both the intervention and the control group will receive usual care.
Study: NCT06556498

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Proflor group
Description: evaluate the surgical outcomes of patients underwent to laparoscopic inguinal hernia repair with Proflor mesh.
Study: NCT05826054

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Montbretin A
Description: The investigational product is 95% pure montbretin A (MbA), a glycosylated acyl-flavonol isolated from the corms (bulbs) of the Crocosmia plant through hot water extraction. It is a potent and specific inhibitor of human pancreatic amylase (HPA).
Study: NCT06141733

Intervention type: OTHER
Intervention: NIRS group
Description: Standard care plus cerebral oxygen saturation monitoring with a dedicated treatment guideline (NIRS-group) during immediate transition (first 15 minutes after birth) and resuscitation.
Study: NCT06271915

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SNAGs - eccentric exercise
Description: intervention done 2 times per week, 45 minutes each session for 4 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SNAGs - eccentric exercise
Description: intervention done 2 times per week, 45 minutes each session for 4 weeks
Study: NCT06642116

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OCEAN
Description: Biodegradable nasal dressing
Study: NCT05157698

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone and Bupropion Combination
Description: Participants in this intervention will take active naltrexone and bupropion pills.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone and Bupropion Combination
Description: Participants in this intervention will take active naltrexone and bupropion pills.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Weight Loss
Description: Participants in this intervention will receive behavioral weight loss treatment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Weight Loss
Description: Participants in this intervention will receive behavioral weight loss treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants in this intervention will take inactive (placebo) pills.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants in this intervention will take inactive (placebo) pills.
Study: NCT06272890

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: motivational interviewing
Description: motivational interviewing
Study: NCT06418308

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: 5 mcg of dexmedetomidine

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine
Description: 200 mcg of epinephrine

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standardized Spinal Mixture
Description: Standardized spinal mixture of 10.25 mg hyperbaric bupivacaine, and 0.125 mg morphine.
Study: NCT06556498

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Progrip group
Description: evaluate the surgical outcomes of patients underwent to laparoscopic inguinal hernia repair with Progrip mesh.
Study: NCT05952934

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: 0.5 mL Candin®/injection
Description: Candin or placebo injection every 3 weeks until 4 injections then every 3 months until a total of 7 injections.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo: 0.5 mL Intravenous 0.9% NaCl solution (Saline)
Description: Placebo injection every 3 weeks until 4 injections then every 3 months until a total of 7 injections.
Study: NCT05413070

Intervention type: BEHAVIORAL
Intervention: Multimodal approach to QI for Low-Value Care
Description: Up to 4 brief educational components in existing quality meetings Informational email/newsletter Individualized performance feedback reports Educational resources for patients
Study: NCT06435728

Intervention type: DIAGNOSTIC_TEST
Intervention: AccuIMR and AccuFFR
Description: AccuFFR and AccuIMR were obtained by reviewing coronary angiography at the time of primary PCI
Study: NCT06145373

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fitusiran (SAR439774)
Description: Pharmaceutical form:Solution for injection-Route of administration:Subcutaneous (SC) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Clotting factor concentrates (CFC) or bypassing agents (BPA)
Description: Pharmaceutical form: Solution for injection-Route of administration: Intravenous (IV) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Antithrombin concentrate (ATIIIC)
Description: Pharmaceutical form:Solution for injection-Route of administration:Intravenous (IV) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Emicizumab
Description: Pharmaceutical form:Solution for injection-Route of administration:SC injection
Study: NCT06217380

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Masimo SafetyNet Alert (MSNA)
Description: This study will explore the feasibility of implementing the Masimo SafetyNet Alert (MSNA) oxygen saturation monitoring system and the acceptance of MSNA by individuals living in a supportive housing program, who inject opioids.
Study: NCT06432231

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low glycemic index diet treatment
Description: This study was a non-randomized, single centre, pre/post-intervention study. A low glycemic index diet was prescribed by a dietician for 3 months. LGID treatment consisted of 10% (40-60 g) low glycaemic index (glycaemic index \<50) carbohydrate, 20-30% protein and 60-70% lipid
Study: NCT05420597

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Induction chemotherapy TP regimen combined with Toripalimab for 3 cycles: Toripalimab 240mg d1, Paclitaxel 175mg/m2 d2，Cisplatin 25mg/m2 d2-4 q3w. Then a total dose of 70Gy in 35 fractions was administered, with concurrently weekly cisplatin (30mg/m2 qw).~At 3-6 weeks post-radiotherapy, maintenance Toripalimab was administered for 8 cycles (240mg d1 q3w, in total 8 cycles).
Study: NCT05645354

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SmokefreeSGM
Description: Participants will be enrolled in a text-based smoking cessation program specifically designed to respond to the needs of LGBTQ+ smokers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SmokefreeTXT
Description: Participants will be enrolled in a text-based smoking cessation program specifically designed to respond to the needs of the general population
Study: NCT05314738

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: NXL Energy 1
Description: Riboflavin drops + NXL System to Total Energy Level 1

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: NXL Energy 1
Description: Riboflavin drops + NXL System to Total Energy Level 1

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: NXL Energy 2
Description: Riboflavin drops + NXL System to Total Energy Level 2

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: NXL Energy 2
Description: Riboflavin drops + NXL System to Total Energy Level 2

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: NXL Energy 3
Description: Riboflavin drops + NXL System to Total Energy Level 3

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: NXL Energy 3
Description: Riboflavin drops + NXL System to Total Energy Level 3

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: NXL Energy 3
Description: Riboflavin drops + NXL System to Total Energy Level 3

Intervention type: COMBINATION_PRODUCT
Group type: SHAM_COMPARATOR
Intervention: Sham Treatment
Description: Sham Drops and No exposure to NXL system
Study: NCT05136352

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: adductor canal block
Description: loco-regional anesthesia using adductor canal block

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: iPACK block
Description: loco-regional anesthesia using infiltration between the popliteal artery and the capsule of the posterior knee
Study: NCT04810871

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Brain Surgery
Description: Undergo surgery