TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05837962

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nursing intervention to improve knowledge and self-care behaviors in the face of HDP
Description: The nursing professional will perform 1 session weekly, for 4 weeks, lasting 90 minutes each. The contents that make up each of the sessions are:~Session 1. Knowledge about the risk factors, signs and symptoms, maternal and fetal complications of HDP.~Session 2. Control over behaviour, positive attitude and family and social support: essential components for conducting self-care behaviour.~Session 3. Nutritional recommendations: eating healthy helps prevent or reduce the risk of developing HDP.~Recommendations to improve sleep, rest and physical exercise: key routines in my health to prevent or reduce the risk of developing HDP.~Session 4. Mental health promotion: managing my stress, anxiety and depression levels help prevent or decrease the risk of HDP
Study: NCT03866499

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BPI-7711
Description: 180 mg, oral, QD

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gefitinib
Description: 250 mg, oral, QD

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Tablet
Description: 250 mg gefitinib placebo tablet, QD

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo capsule
Description: 180 mg BPI-7711 placebo capsule, QD
Study: NCT05416073

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: PCIA formula：100ml analgesic solution was prepared by adding 2.5 mg/kg Esketamine and 8mg ondansetron into normal saline.~30min before TACE treatment, the first dose of 2ml was slowly injected intravenously. No obvious adverse reactions were observed for 10min. After that, the intravenous analgesia pump was started. Parameter setting of intravenous analgesia pump: the total volume is 100ml; The duration is 2ml / h; The single dose is 2ml each time; The limit quantity is 10ml / h; The locking time was 10min and the analgesia lasted for 48h.~The target value of analgesia in this study was NRS (Numerical Rating Scale)\< 4; If NRS ≥ 4, when the effect is still poor after adding drugs by pressing the analgesic pump, the investigators will give the remedial drug(dolantin 50mg im st) according to the patient's condition.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sufentanil
Description: PCIA formula：100ml analgesic solution was prepared by adding 2 μ g/kg sufentanil and 8mg ondansetron into normal saline.~30min before TACE treatment, the first dose of 2ml was slowly injected intravenously. No obvious adverse reactions were observed for 10min. After that, the intravenous analgesia pump was started. Parameter setting of intravenous analgesia pump: the total volume is 100ml; The duration is 2ml / h; The single dose is 2ml each time; The limit quantity is 10ml / h; The locking time was 10min and the analgesia lasted for 48h.~The target value of analgesia in this study was NRS (Numerical Rating Scale)\< 4; If NRS ≥ 4, when the effect is still poor after adding drugs by pressing the analgesic pump, the investigators will give the remedial drug(dolantin 50mg im st) according to the patient's condition.
Study: NCT05462392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: robot-assisted surgery
Description: urological surgeries, such as partial nephrectomy, radical cystectomy, and radical prostatectomy was performed for patients using the Micro Hand S robot group.

Intervention type: DEVICE
Group type: OTHER
Intervention: robot-assisted surgery
Description: urological surgeries, such as partial nephrectomy, radical cystectomy, and radical prostatectomy was performed for patients using the da Vinci robot group
Study: NCT06370520

Intervention type: BEHAVIORAL
Intervention: Validated Questionnaires
Description: Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-8 (PHQ-8), The Rivermead Post Concussion Symptom Questionnaire (Rivermead), Pediatric Quality of Life Inventory (PedsQL), Strengths and Difficulties Questionnaire (SDQ)

Intervention type: BEHAVIORAL
Intervention: Validated Questionnaires
Description: Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-8 (PHQ-8), The Rivermead Post Concussion Symptom Questionnaire (Rivermead), Pediatric Quality of Life Inventory (PedsQL), Strengths and Difficulties Questionnaire (SDQ)

Intervention type: BEHAVIORAL
Intervention: Questionnaires
Description: Early Physical Activity/Return to School Questionnaire, Mental Health Utilization Questionnaire
Study: NCT05250232

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: onlays conservative
Description: Partial coverage of cusps with shoulder finish line

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: onlays conventional
Description: all coverage of cusps as overlay with shoulder finish line
Study: NCT06158581

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Emotion Awareness and Skills Enhancement Program
Description: EASE is a cutting-edge program created by researchers at the University of Alabama and the University of Pittsburgh in collaboration with autistic individuals, caregivers of autistic youth, and therapists. The overarching goal of the program is to support autistic clients who want to work on emotion regulation. EASE is unique because it targets emotional distress in autistic youth and adults, instead of targeting the core symptoms of autism (i.e., it is not a social skills intervention).~The program is a 16-session, mindfulness-based intervention. Each session is 1:1 for 45 minutes to one hour. While the program is designed for individual intervention, caregivers are also invited to play an active role on the care team.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: The Unified Protocol
Description: UP is a thoroughly-studied, manualized intervention created by researchers at the University of Miami in conjunction with researchers at Boston University. The program was designed to be customizable to meet the needs of people with a variety of diagnoses, allowing more individuals to access emotion regulation resources. The protocol also has different modules to accommodate different developmental levels (UP-Children, UP-Adolescent, UP-Adult). The overall goal of UP is to help clients identify emotions and build new strategies to cope with stressful life situations and distressing emotions.~The protocol is flexible, with each session is about 45 to 60 minutes and the number of sessions varying between 12 - 21 sessions. For the current study, the treatment will take place over 16 sessions. The intervention is cognitive behavioral therapy (CBT) based but also includes hints of mindfulness-based intervention strategies.
Study: NCT06370520

Intervention type: BEHAVIORAL
Intervention: Questionnaires
Description: Early Physical Activity/Return to School Questionnaire, Mental Health Utilization Questionnaire

Intervention type: OTHER
Intervention: Clinician / Medical Record Variables
Description: Medical History, Emergency Department Clinical Variables

Intervention type: OTHER
Intervention: Clinician / Medical Record Variables
Description: Medical History, Emergency Department Clinical Variables
Study: NCT06083597

Intervention type: OTHER
Intervention: Qualitative interview
Description: Qualitative interviews will be performed on women with chronic pelvic pain of venous origin.

Intervention type: OTHER
Intervention: Qualitative interview
Description: Qualitative interviews will be performed on women with chronic pelvic pain of venous origin.
Study: NCT06609824

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Leer te Durven!
Description: 'Leer te Durven!' is an eight-week preventative group training for children between the ages of 8 and 12. This training is evidence-based and is based on the principles of Cognitive Behavioral Therapy. With this program children learn to stand up for themselves in a safe environment, to face the situations that they find exciting and to be more confident in their own abilities. The training consists, among other things, of psychoeducation, exposure, and relaxation.
Study: NCT04721756

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-LY3546117 Injection
Description: 370 megabecquerel (MBq) intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-LY3546117 Injection
Description: 370 megabecquerel (MBq) intravenous injection
Study: NCT05822466

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtual tai ji quan: moving for better balance intervention (V-TJQMBB)
Description: This intervention involves a tai ji quan exercise program, named tai ji quan: moving for better balance

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtual multimodal exercise intervention (V-Multimodal)
Description: This intervention involves a multimodal exercise program that consists of balance, strength, light walking, and stretching exercises
Study: NCT05778565

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extraocular muscle stretching
Description: Extraocular muscle stretching to test its efficacy as a weakening procedure
Study: NCT04721756

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PET Scan
Description: positron emission tomography (PET) scan

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PET Scan
Description: positron emission tomography (PET) scan
Study: NCT05680623

Intervention type: DIAGNOSTIC_TEST
Intervention: PPAP diagnosis
Description: Serum amylase (total or the pancreatic isoform) and/or lipase activity will be systematically measured at least on postoperative days 1 and 2.~A CT with pancreas protocol iv contrast infusion will be performed in the postoperative course when clinically required, facing patients' clinical worsening, suspicious of abdominal complications.
Study: NCT05389917

Intervention type: PROCEDURE
Intervention: Pancreaticoduodenectomy
Description: In Pre Operative phase~64 Slice MD CT scan will be taken in all patients undergoing PD in pre op period 3D reconstruction of Peripancreatic vascular system using MDCT images Measure longitudinal distance between Root of Left renal vein, origin of IPDA Measure distance between origin of SMA , MCA and the IPDA~In Intraoperative period~Distance will be measured using standard disposable ruler from Root of Left renal vein to IPDA after Transection of Pancreas followed by specimen removal and to measure the distance between MCA, SMA and IPDA using standard disposable ruler .
Study: NCT06118203

Intervention type: DRUG
Intervention: Semaglutide
Description: Semaglutide in addition to standard of care
Study: NCT04962932

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-deliviered exposure-based CBT
Description: The intervention lasts for 10 weeks and include: Education, Interoceptive exposure, exposure in-vivo, combining in-vivo exposure with interoceptive exposure, behavioral activation and relapse prevention. Include the guidance of a minimum weekly contact with a CBT psychologist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Internet-delivered stress management treatment
Description: The intervention last for 10 weeks and include: Internet-SMT include life-style advice (e.g., exercise, sleep advice), relaxation and problem-solving skills to reduce stress. Patients are offered regular online contact with a psychologist with the same frequency and intensity as in the CBT arm.
Study: NCT05295420

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: platelet rich plasma
Description: Injection of Platelet Rich Plasma in the female conditions that suffer from SUI
Study: NCT06324136

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Implementation of the diagnostic algorithm
Description: Patients will be selected based on specific clinical criteria and referred to the tertiary center for genetic testing. All selected patients will undergo genetic testing by whole-exome sequencing (WES), followed by in silico analysis for an extended panel of genes associated with kidney diseases. The results of genetic testing will be evaluated by a multidisciplinary team of experts to establish conclusive diagnosis.
Study: NCT05857839

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial release
Description: Patients will get myofascial release technique to sacroiliac joint area for up to 600 seconds and total treatment sessions will be 12 in 4 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial release
Description: Patients will get myofascial release technique to sacroiliac joint area for up to 600 seconds and total treatment sessions will be 12 in 4 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pelvic Support belt
Description: The support belt will be worn for less than two to three hours at a time and it will be used 4 times a week
Study: NCT05854758

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core strengthening with conventional treatment
Description: A detailed musculoskeletal examination of lumbar spine will be performed before the start of treatment. Oswestry Low Back Pain Disability Questionnaire for pain will be noted. An expert physical therapist with more than 7 years clinical experience will assist the patients in performing core stabilization exercise with conventional physical therapy protocol and routine physical therapy exercise. The session with the physical therapist will usually last for up to 40 minutes.~This group will perform planks, side planks and superman exercises along with knee to chest, pelvic rotation, back extension, and bridge exercises after baseline treatment of therapeutic hot pack and transcutaneous electrical nerve stimulation. continuous mode for 10 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: A detailed musculoskeletal examination of lumbar spine will be performed before the start of treatment. Oswestry Low Back Pain Disability Questionnaire for pain will be noted. An expert physical therapist with more than 7 years clinical experience will assist the patients in performing core stabilization exercise with conventional physical therapy protocol and routine physical therapy exercise. The session with the physical therapist will usually last for up to 40 minutes.~This group will perform knee to chest, pelvic rotation, bridge and back extension exercises after baseline treatment of therapeutic hot pack and transcutaneous electrical nerve stimulation. continuous mode for 10 minutes. Each exercise will be repeated 10 times, with 10 second holds, followed by a five-minute rest interval
Study: NCT05197166

Intervention type: OTHER
Intervention: Acute Clinical Settings
Description: Acute clinical settings, like hospitals, where students are exposed to normal daily shift activities, involving prolonged walking and standing positions.
Study: NCT04609306

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: H2O2 application to incision
Description: A lap sponge soaked in 3% H2O2 will be applied to the incision and allowed to sit for 3 minutes.
Study: NCT06063018

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48 + Tislelizumab
Description: RC48: intravenous drip, 2mg/kg, D1, repeated once every 2 weeks. Tislelizumab: intravenous drip, fixed dose 600 mg, D1, repeated once every 6 weeks.
Study: NCT05451836

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient education leaflets
Description: Patients who attend the emergency department with upper respiratory tract infections will be provided with patient education leaflets on appropriate antibiotic use and antimicrobial resistance. The leaflets are available in the four national languages in Singapore.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient education leaflets
Description: Patients who attend the emergency department with upper respiratory tract infections will be provided with patient education leaflets on appropriate antibiotic use and antimicrobial resistance. The leaflets are available in the four national languages in Singapore.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physician feedback
Description: All physicians working in the emergency department will receive a text message from their department head on their antibiotic prescribing rates every two months.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physician feedback
Description: All physicians working in the emergency department will receive a text message from their department head on their antibiotic prescribing rates every two months.
Study: NCT05528016

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Upper Eyelid Blepharoplasty
Description: Blepharoplasty is a procedure that the skin, orbicularis oculi muscle, and fat pads are excised to treat visual field loss caused by dermatochalasis.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Upper Eyelid Blepharoplasty
Description: Blepharoplasty is a procedure that the skin, orbicularis oculi muscle, and fat pads are excised to treat visual field loss caused by dermatochalasis.
Study: NCT04661800

Intervention type: OTHER
Group type: OTHER
Intervention: Sniffin's stick test
Description: The sniffin's stick test is a three-part test consisting of smelling odor pens: 1) determining a detection threshold, 2) discriminating ability, 3) ability to identify odors. It lasts about 30 minutes, is achievable in the room.
Study: NCT05223127

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aloe vera
Description: The leaves of Aloe vera (Aloe barbadensis) will be identified and verified by Selçuk University Faculty of Agriculture. Aloe vera leaves will be washed with antiseptic solution and cut crosswise using gloves and sterile knife. The thick epidermis will be removed from the middle of the leaf. The gel will be obtained from the parenchyma of the thick juicy leaves of aloe vera.
Study: NCT05157373

Intervention type: DIAGNOSTIC_TEST
Intervention: Endometrial sampling and Peripheral blood collection
Description: The endometrial biopsy will be performed with a pipette. The pipelle will be inserted gently through the cervix and into the uterus. The pipelle procedure takes approximately one minute and involves gently moving the pipelle back and forth to obtain a sample. Then 10cc of peripheral blood will be collected.

Intervention type: DIAGNOSTIC_TEST
Intervention: Endometrial sampling and Peripheral blood collection
Description: The endometrial biopsy will be performed with a pipette. The pipelle will be inserted gently through the cervix and into the uterus. The pipelle procedure takes approximately one minute and involves gently moving the pipelle back and forth to obtain a sample. Then 10cc of peripheral blood will be collected.

Intervention type: DIAGNOSTIC_TEST
Intervention: Endometrial sampling and Peripheral blood collection
Description: The endometrial biopsy will be performed with a pipette. The pipelle will be inserted gently through the cervix and into the uterus. The pipelle procedure takes approximately one minute and involves gently moving the pipelle back and forth to obtain a sample. Then 10cc of peripheral blood will be collected.

Intervention type: BEHAVIORAL
Intervention: FSFI Scale
Description: The participants will fill up the Female Sexual Function Index (FSFI) questionnaire.~The FSFI is a 19-item self-report questionnaire designed to measure sexual functioning in women. It assesses six domains of sexual function: sexual desire, sexual arousal, lubrication, orgasm, satisfaction, and pain (i.e., pain associated with vaginal penetration).

Intervention type: BEHAVIORAL
Intervention: FSFI Scale
Description: The participants will fill up the Female Sexual Function Index (FSFI) questionnaire.~The FSFI is a 19-item self-report questionnaire designed to measure sexual functioning in women. It assesses six domains of sexual function: sexual desire, sexual arousal, lubrication, orgasm, satisfaction, and pain (i.e., pain associated with vaginal penetration).

Intervention type: BEHAVIORAL
Intervention: FSFI Scale
Description: The participants will fill up the Female Sexual Function Index (FSFI) questionnaire.~The FSFI is a 19-item self-report questionnaire designed to measure sexual functioning in women. It assesses six domains of sexual function: sexual desire, sexual arousal, lubrication, orgasm, satisfaction, and pain (i.e., pain associated with vaginal penetration).
Study: NCT05993104

Intervention type: DIAGNOSTIC_TEST
Intervention: Intrachamber ultrasound
Description: Ultrasound left atrial geometry collecting using AcQMap.

Intervention type: OTHER
Intervention: Statistical shape analysis
Description: Statistical shape analysis tools used to investigate left atrial geometry

Intervention type: OTHER
Intervention: Statistical shape analysis
Description: Statistical shape analysis tools used to investigate left atrial geometry
Study: NCT06037980

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: ◦ Gemcitabine 800 mg/mq iv, day 1 and 8 of 21-day cycles, for 3 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: ◦ Nab-paclitaxel 100 mg/mq, day 1 and 8 of 21-day cycles, for 3 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ◦ Cisplatin 25 mg/mq iv, day 1 and 8 of 21-day cycles, for 3 cycles

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Curative Surgery
Description: Curative surgery on primary tumor

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Curative Surgery
Description: Curative surgery on primary tumor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 1250 mg/m2 given orally twice daily on days 1 to 14 of a 3 weekly cycle for a total of 8 cycles

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: 1250 mg/m2 given orally twice daily on days 1 to 14 of a 3 weekly cycle for a total of 8 cycles
Study: NCT05534438

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy
Description: SBRT will be initiated as soon as possible, at not beyond 8 weeks of baseline measurements. Recommended dosing is per department standards for oligometastatic disease (ie, 10 Gy x 3 or 7-8 Gy x 5 fractions daily, excluding weekends and departmental holidays)
Study: NCT05313308

Intervention type: DRUG
Intervention: Midazolam
Description: Midazolam oromucosal solution
Study: NCT06294470

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Ballon expulsion test
Description: Rectal latex balloon probe filled with saline solution. Patients expelled balloon and time recorded (\<1 or \>1 min).

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ballon expulsion test
Description: Rectal latex balloon probe filled with saline solution. Patients expelled balloon and time recorded (\<1 or \>1 min).
Study: NCT05541510

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AD17002 + Formulation buffer
Description: Intranasal innate immune modulator
Study: NCT06294470

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Colonic transit time
Description: Patients ingested capsules with 24 radiopaque markers and underwent standing abdominal radiographs on Day 3 and Day 5. Over 80% expulsion within five days was considered normal, while retention indicated defecatory obstruction.
Study: NCT05541510

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AD17002 + Formulation buffer
Description: Intranasal innate immune modulator

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Formulation buffer