TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04170361

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Chest Physiotherapy
Description: All patients will be admitted to physiotherapy rehabilitation program including breathing exercises, modified postural drainage and percussion, lower-upper extremity mobilization exercises and posture exercises once a day during hospitalization. In addition, patients in the education group will be taught the use of Triflo ® and administered at two-hour intervals. The program will be started within the first 24 hours and blood pressure, heart rate, oxygen saturation and respiratory frequency will be recorded before and after the sessions. The values obtained from the second session of the patients will be included in the analysis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Chest Physiotherapy
Description: All patients will be admitted to physiotherapy rehabilitation program including breathing exercises, modified postural drainage and percussion, lower-upper extremity mobilization exercises and posture exercises once a day during hospitalization. In addition, patients in the education group will be taught the use of Triflo ® and administered at two-hour intervals. The program will be started within the first 24 hours and blood pressure, heart rate, oxygen saturation and respiratory frequency will be recorded before and after the sessions. The values obtained from the second session of the patients will be included in the analysis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Chest Physiotherapy+Incentive Spirometry
Description: All patients will be admitted to physiotherapy rehabilitation program including breathing exercises, modified postural drainage and percussion, lower-upper extremity mobilization exercises and posture exercises once a day during hospitalization. In addition, patients in the education group will be taught the use of Triflo ® and administered at two-hour intervals. The program will be started within the first 24 hours and blood pressure, heart rate, oxygen saturation and respiratory frequency will be recorded before and after the sessions. The values obtained from the second session of the patients will be included in the analysis.In addition, patients in the education group will be taught the use of Triflo ® and administered at two-hour intervals.
Study: NCT04506008

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Ultra-Hypo-fractionation Radiotherapy
Description: Five fractions of pre-operative radiation

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resection
Description: Surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resection
Description: Surgery

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Moderately-Hypo-fractionation Radiotherapy
Description: 15 fractions of pre-operative radiation
Study: NCT06073600

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin / Vildagliptin Reference Film Coated Tablets (1000 mg / 50 mg) (Galvumet®)
Description: The subjects randomly received a single oral administration of Metformin / Vildagliptin Film Coated Tablets (1000 mg / 50 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin / Vildagliptin Reference Film Coated Tablets (1000 mg / 50 mg) (Galvumet®)
Description: The subjects randomly received a single oral administration of Metformin / Vildagliptin Film Coated Tablets (1000 mg / 50 mg).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin / Vildagliptin Test Film Coated Tablets (1000 mg / 50 mg)
Description: The subjects randomly received a single oral administration of Metformin / Vildagliptin Film Coated Tablets (1000 mg / 50 mg).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin / Vildagliptin Test Film Coated Tablets (1000 mg / 50 mg)
Description: The subjects randomly received a single oral administration of Metformin / Vildagliptin Film Coated Tablets (1000 mg / 50 mg).
Study: NCT05705609

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mandala art therapy
Description: A mandala is a geometric configuration of symbols. In various spiritual traditions, mandalas may be employed for focusing attention of practitioners and adepts, as a spiritual guidance tool, for establishing a sacred space and as an aid to meditation and trance induction. Mandalas are used effectively in the field of art therapy. The possibility of using mandala in all age groups has contributed to the treatment process of different diseases and disorders, and its effectiveness has been presented to the scientific world with many researches around the globe. As a result of using mandala as an art therapy in adults, mandala has been used both in the treatment of psychiatric disorders and has been a tool used to observe the effects of the treatments. Art therapy which included drawing mandala, significantly reduced the severity of trauma symptoms in individuals with anxiety disorders and post-traumatic stress disorder.
Study: NCT04870528

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: pulsed electromagnetic field device
Description: the pulsed electromagnetic field device treatment parameters will be set as 15 Hz frequency, 20 gauss amplitude, and 20 minutes as total treatment duration.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Free weights for Strengthening Exercise
Description: • Parameters of the exercise program: Intensity : The weight or load the patients lifted is set at 50-60% of their individual 1RM , 3 sets of 10 repetitions during the first week. During the second week, the lifting load is increased to 70-75% (3 sets of 10 repetitions) of their individual 1RM and continued for weeks 2-6. After this, training intensity is increased to 80-85% of the 1 RM and implemented from weeks 7-8.~Frequency: 3 sessions per week for 8 weeks. Number of repetitions: 3 sets,10 repetitions in each set. Total treatment duration: 8 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Free weights for Strengthening Exercise
Description: • Parameters of the exercise program: Intensity : The weight or load the patients lifted is set at 50-60% of their individual 1RM , 3 sets of 10 repetitions during the first week. During the second week, the lifting load is increased to 70-75% (3 sets of 10 repetitions) of their individual 1RM and continued for weeks 2-6. After this, training intensity is increased to 80-85% of the 1 RM and implemented from weeks 7-8.~Frequency: 3 sessions per week for 8 weeks. Number of repetitions: 3 sets,10 repetitions in each set. Total treatment duration: 8 weeks
Study: NCT06037798

Intervention type: OTHER
Intervention: cranio-cervical flexion test with NOD
Description: testing the anterior neck muscles during a nodding movement and by using a dynamometer

Intervention type: OTHER
Intervention: cranio-cervical flexion test with NOD
Description: testing the anterior neck muscles during a nodding movement and by using a dynamometer
Study: NCT06359873

Intervention type: DIAGNOSTIC_TEST
Intervention: CHA2DS2-VASc score, C2HEST score, and left atrial diameter (LAD)
Description: CHA2DS2-VASc Score: Congestive heart failure (HF) \[1 point\], hypertension \[1 point\], age ≥ 75 years \[2 points\], diabetes \[1 point\], prior stroke or transient ischemic attack \[2 points\], vascular disease \[1 point\], age 65-74 years \[1 point\], and female gender\[1 point\].~C2HEST Score: Coronary artery disease or chronic obstructive pulmonary disease \[1 point each, 2 total points\]; hypertension \[1 point\]; elderly \[2 points for age ≥ 75 years\]; systolic HF \[2 points\]; and thyroid disease \[1 point for hyperthyroidism\]\[10\].~LAD: The LAD values of the enrolled patients were extracted by keyword search based on the results of echocardiography in the database.

Intervention type: DIAGNOSTIC_TEST
Intervention: CHA2DS2-VASc score, C2HEST score, and left atrial diameter (LAD)
Description: CHA2DS2-VASc Score: Congestive heart failure (HF) \[1 point\], hypertension \[1 point\], age ≥ 75 years \[2 points\], diabetes \[1 point\], prior stroke or transient ischemic attack \[2 points\], vascular disease \[1 point\], age 65-74 years \[1 point\], and female gender\[1 point\].~C2HEST Score: Coronary artery disease or chronic obstructive pulmonary disease \[1 point each, 2 total points\]; hypertension \[1 point\]; elderly \[2 points for age ≥ 75 years\]; systolic HF \[2 points\]; and thyroid disease \[1 point for hyperthyroidism\]\[10\].~LAD: The LAD values of the enrolled patients were extracted by keyword search based on the results of echocardiography in the database.

Intervention type: DIAGNOSTIC_TEST
Intervention: CHA2DS2-VASc score, C2HEST score, and left atrial diameter (LAD)
Description: CHA2DS2-VASc Score: Congestive heart failure (HF) \[1 point\], hypertension \[1 point\], age ≥ 75 years \[2 points\], diabetes \[1 point\], prior stroke or transient ischemic attack \[2 points\], vascular disease \[1 point\], age 65-74 years \[1 point\], and female gender\[1 point\].~C2HEST Score: Coronary artery disease or chronic obstructive pulmonary disease \[1 point each, 2 total points\]; hypertension \[1 point\]; elderly \[2 points for age ≥ 75 years\]; systolic HF \[2 points\]; and thyroid disease \[1 point for hyperthyroidism\]\[10\].~LAD: The LAD values of the enrolled patients were extracted by keyword search based on the results of echocardiography in the database.
Study: NCT05927051

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stabilization exercises
Description: Core stability exercises will be performed three days in a week. Treatment will continue an hour in per session for 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: McKenzie exercises
Description: McKenzie exercises will be performed three days in a week. Treatment will continue an hour in per session for 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home exercises
Description: Home exercises will be performed three days in a week. Treatment will continue an hour in per session for 8 weeks
Study: NCT06077604

Intervention type: OTHER
Intervention: Assessment of exposure to air pollution
Description: For each patient, exposure to air pollution will be assessed over a period immediately prior to any flare-up and over four periods at a distance from the flare-up.
Study: NCT06033573

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: contrast-enhanced spectral mammography
Description: After enrollment, subjects should undergo contrast-enhanced spectral mammography again within 4-6 hours post completing previous routine ductography to obtain a late-phase ductal image, which contains a low-energy image and a subtracted image obtained from the post processing
Study: NCT05779462

Intervention type: OTHER
Intervention: Dynamic MRI Sequence
Description: Addition of a Dynamic MRI Sequence during the MRI examination performed in routine care

Intervention type: OTHER
Intervention: Dynamic MRI Sequence
Description: Addition of a Dynamic MRI Sequence during the MRI examination performed in routine care
Study: NCT04808531

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NanaBis™
Description: NanaBis™ is a nanoparticle water soluble equimolar solution of d9-THC \& CBD. One dose is equivalent to 2 actuations of the pump delivering 280 µL volume containing 2.5 mg d9-THC and 2.5 mg CBD

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxycodone CR
Description: Oxycodone CR tablet is an opioid agonist supplied in 10 mg, 15 mg, 20 mg, 30 mg,40 mg, 60 mg and 80 mg tablets for oral administration. The tablet strengths describe the amount of oxycodone per tablet as the hydrochloride salt.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Spray
Description: Placebo comparator used against both NanaBis™ and Oxycodone depending on randomisation of arms.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Spray
Description: Placebo comparator used against both NanaBis™ and Oxycodone depending on randomisation of arms.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Tablet
Description: Placebo comparator used against both NanaBis™ and Oxycodone depending on randomisation of arms.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Tablet
Description: Placebo comparator used against both NanaBis™ and Oxycodone depending on randomisation of arms.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxycodone IR
Description: Oxycodone immediate release (IR) tablet or capsule or oral solution used as breakthrough analgesia.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxycodone IR
Description: Oxycodone immediate release (IR) tablet or capsule or oral solution used as breakthrough analgesia.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone IR
Description: Oxycodone immediate release (IR) tablet or capsule or oral solution used as breakthrough analgesia.
Study: NCT04291950

Intervention type: PROCEDURE
Intervention: Needle core biopsy
Description: Blood draws will be done in OR by research staff. Tissue will be obtained at the time of their definitive surgery or at the time of port placement. For women going to surgery first, four (4) 16-gauge core needle biopsies will be obtained by research staff after the tumor has been removed from the patient and the specimen is on the collection table in the OR.~For women who are getting neo-adjuvant therapy prior to surgery, the core needle biopsies will be collected at the time of port placement in the OR. The patient will be under light anesthesia for the port placement. Per standard care, we will also use local anesthetic for the needle core biopsy. Port placement requires ultrasound (US). We will take advantage of the US already available in the OR to guide the core needle biopsy. Within 30 minutes of procurement, the tissue from the biopsies will be flash frozen in liquid nitrogen by staff and taken to the lab.

Intervention type: PROCEDURE
Intervention: Needle core biopsy
Description: Blood draws will be done in OR by research staff. Tissue will be obtained at the time of their definitive surgery or at the time of port placement. For women going to surgery first, four (4) 16-gauge core needle biopsies will be obtained by research staff after the tumor has been removed from the patient and the specimen is on the collection table in the OR.~For women who are getting neo-adjuvant therapy prior to surgery, the core needle biopsies will be collected at the time of port placement in the OR. The patient will be under light anesthesia for the port placement. Per standard care, we will also use local anesthetic for the needle core biopsy. Port placement requires ultrasound (US). We will take advantage of the US already available in the OR to guide the core needle biopsy. Within 30 minutes of procurement, the tissue from the biopsies will be flash frozen in liquid nitrogen by staff and taken to the lab.
Study: NCT05352503

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Watching videos with nature images accompanied by nature sounds with virtual reality glasses
Description: The video with nature images accompanied by the sounds of nature with virtual reality glasses will be watched 3 times a day for at least 5 minutes for 2 days.
Study: NCT05867238

Intervention type: OTHER
Intervention: Training stress management
Description: The stress management training included 1 day and a half day. It was given by a therapist trained in transactional analysis and a trainer from the nurse anaesthetist school. The training was based on cognitive behavioural stress management training and the use of stress management exercises: cardiac coherence, mindfulness meditation, muscle relaxation, mental imagery.
Study: NCT05779475

Intervention type: OTHER
Intervention: No treatment given
Description: Participants will not receive any investigational treatment in this study.
Study: NCT04610021

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: i-FactorTM Bone graft
Description: In the i-Factor ™ group it will be placed longitudinally in the intertransverse area. Likewise, in both groups, only autologous and bench bone will be placed in the intersomatic cages. The vertebrae where the i-Factor ™ is placed will be noted on the data collection sheet.
Study: NCT05467514

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liraglutide
Description: Application of liraglutide 1.8 mg subcutaneous daily for 6 months to evaluate subclinical atherosclerosis, by means of carotid doppler US, lipid profile in patients with type 1 diabetes mellitus
Study: NCT06190067

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine Plus PD-1 therapy
Description: Patients were treated by Azacytidine(75 mg/m2 subcutaneous injection qd on days 1-7) plus PD-1 therapy(200mg iv qd d8)
Study: NCT05349929

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gelofen (generic name of Ibuprofen in Iran)
Description: Gelofen capsules, 400mg Ibuprofen, Dana pharma company, every 6hours

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anahil ( generic name of Bromelain in Iran)
Description: Anahil capsules,200 mg Bromelain, Permon Amin Health Company,every 6hours

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Root Canal Therapy
Description: all the participants go under RCT.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Root Canal Therapy
Description: all the participants go under RCT.
Study: NCT06042218

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Xiaxi intervention program
Description: The Xiaxi sessions will follow the same structure in both intervention groups. First of all, 8-minute warm-up where the participants will work on: postural awareness; active static stretching of the pectoral, hamstring and psoas muscles; and mobility. The main part will include the following blocks of content during the 12 weeks of intervention (46 minutes will be spent on this part in each session): breathing; mobility; active and dynamic static stretching of the tonic muscles with effects on the spine dynamic; strength of the phasic muscles with effects on the spine dynamic, alternating upper limb, lower limb and core; postural awareness; and passive static stretching of the tonic muscles with effects on the spine dynamic. The cool down will be similar in each session (6 minutes) and will focus on: postural awareness and passive static stretching of the pectoral, hamstring and psoas muscles.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Xiaxi intervention program
Description: The Xiaxi sessions will follow the same structure in both intervention groups. First of all, 8-minute warm-up where the participants will work on: postural awareness; active static stretching of the pectoral, hamstring and psoas muscles; and mobility. The main part will include the following blocks of content during the 12 weeks of intervention (46 minutes will be spent on this part in each session): breathing; mobility; active and dynamic static stretching of the tonic muscles with effects on the spine dynamic; strength of the phasic muscles with effects on the spine dynamic, alternating upper limb, lower limb and core; postural awareness; and passive static stretching of the tonic muscles with effects on the spine dynamic. The cool down will be similar in each session (6 minutes) and will focus on: postural awareness and passive static stretching of the pectoral, hamstring and psoas muscles.
Study: NCT05479214

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: 1gm tablet with the 2 main meals

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin
Description: subcutaneous insulin daily administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin
Description: subcutaneous insulin daily administration
Study: NCT05595187

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tricuspid repair
Description: Tricuspid repair included suture placement and the type of prosthetic annuloplasty.
Study: NCT04945603

Intervention type: OTHER
Intervention: Standard management according to international/national guidelines
Description: Standard management according to international/national guidelines. Observational study
Study: NCT06360263

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Densah bur in combination with activated plasma albumin gel
Description: Simultaneous implant placement after transcrestal maxillary sinus lifting using densah burs in combination with activated plasma albumin gel.(APAG). A full mucoperiosteal flap will be elevated, and then reflected with periosteal elevator application of first densah bur (the narrowest) with densifying mood (reverse) counterclockwise, 800-1500 revolutions per minute with copious irrigation until the sinus is reached confirm bur position with a radiograph. Then a wider densah bur (3.0) is used with the same mode and bouncing motion to elevate the sinus floor up to 3 mm in 1mm increments.The sequential densah bur will be used with the same mode and bouncing motion to elevate the the sinus floor 3 mm maximum. After achieving the final planned osteotomy diameter, the osteotomy will be filled with APAG. Then, the desired implant length is inserted.
Study: NCT06076421

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fact box
Description: Fact boxes provide a tabular or graphical overview of the benefits and harms of the COVID-19 or influenza vaccination through transparent risk communication. The fact boxes are available for two different age groups each: COVID-19 vaccination for people aged 18 to 59 and over 60, influenza vaccination for people aged 16 to 64 and over 65 in Arabic, German, Russian and Turkish.
Study: NCT05112536

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trilaciclib
Description: Trilaciclib is administered IV as monotherapy during the lead-in phase and administered prior to chemotherapy on each day chemotherapy is administered during the treatment phase.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cylophosphamide
Description: Cyclophosphamide administered IV every 2 weeks for the first 4 cycles (1-4), each cycle 2 weeks in length.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Doxorubicin administered as an IV bolus every 2 weeks for the first 4 cycles (1-4), each cycle 2 weeks in length.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel administered weekly for the last 12 cycles (cycles 5-16), each cycle 1 week in length.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin (Investigator discretion)
Description: Carboplatin, if given, is administered IV weekly at the start of paclitaxel administration, for the last 12 cycles (cycles 5-16).

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab (Investigator discretion)
Description: Pembrolizumab, if given, is administered IV every 6 weeks throughout the treatment phase (cycles 1, 4, 9, 15).