TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06604962

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IMES using IEP
Description: First group (n=12) received IMES using inverse electrode placement. The needle electrode inserted into the paraspinal region was connected to the active or cathode pole of the electrical stimulator. The reference or anode pole of the electrical stimulator was connected to the electrode that was inserted into the MTrP area of the UT muscle. The muscle was stimulated for 10 min with a tolerable intensity in a single session to induce muscle relaxation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: IMES using CEP
Description: Second group (n=12) underwent IMES with conventional electrode placement. In this group, the cathode pole of the stimulator was connected to the needle inserted into the UT muscle, and the anode pole was connected to the needles of the paraspinal region of the cervical spine. Needle electrodes were connected using alligator clip connectors. The muscle was stimulated for 10 min with a tolerable intensity in a single session to induce muscle relaxation.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham-IMES
Description: Third group (n=12) received sham-IMES. Similar to the experimental intervention groups, the cathode pole of the stimulator was connected to the needle inserted into the UT muscle, and the anode pole was connected to the needles of the paraspinal region of the cervical spine. However, the delivered IMES was very minimal intensity
Study: NCT06667193

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion (CWI) - Cold Tub Immersion (CI)
Description: Once thermoneutral procedures are complete, participants in the CI group will be seated in the cold tub and submerged into the water (10º C). The sternal notch of each participant will be used as the anatomical marker to mark submersion point. Participants will sit with both arms outstretched underwater with their backs not touching the sides of the tub. Participants with a shorter stature will be provided an underwater cushion to meet the submersion requirements. The 4-minute timer will begin once confirmation of the participants submersion level and posture is determined. Once completed, the participant will be instructed to slowly exit the tub and allowed to dry and change as necessary.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion (CWI) - Cold Shower (CS)
Description: Once thermoneutral procedures are complete, participants in the CS group will be instructed to enter the research shower area in Gunter 1610. Within the shower area, the walls of the shower will be numbered from 1 to 4, with 1 defined as facing the faucet, 2 defined as 90° to the right of side 1, 3 defined as 180° from the faucet, and 4 defined as 270° to the right or 90° C to the left from side 1. Participants will be instructed to turn 90° to the right cycling through sides 1 to 4 and then back to 1 every 15 seconds prompted by the researcher. This will allow the participant to complete three full rotations in the shower during the 4-minute intervention time. The shower faucet is modified and oriented in a way where it only produces cold water (10º C) when turned on. Once completed, the participant will be instructed to slowly exit the shower and is allowed to dry and change as necessary.
Study: NCT06666777

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention focused on intersubjective prelinguistic and socio-communicative skills
Description: The intervention consists of 8 45-minute, weekly sessions over two months. These sessions may take place in various settings, such as free play, snack time, or structured activities. The speech therapist will use these settings to help parents observe intersubjective and social-communicative behaviors, providing guidance and strategies to support them.~The following topics will be addressed: Attention; Multisensory Stimulation and Integration: Sensitivity and Responsiveness; Communicative Codes and Preference/Discrimination; Gestures; Intentionality and Communicative Styles.~These topics are not structured into rigid levels for each session. Instead, several topics may be addressed within the same session and revisited across multiple sessions. This flexibility allows the speech therapist to adapt the intervention based on observations, interactions with the child, and discussions with the parent.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard speech therapy intervention
Description: The standard speech therapy intervention, as typically conducted in rehabilitation centers, consists of 8 weekly sessions, each lasting 45 minutes, over a two-month period (same as the experimental intervention). During these sessions, the therapist may provide various stimulations aimed at enhancing the child's vocalization, verbal comprehension, and speech production. While the therapist may offer guidance to parents on how to continue these stimulations in daily routines, they will not be directly involved in the sessions unless strictly necessary.
Study: NCT06668272

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Small Changes program
Description: Participants will be asked to track their compliance with their Small Changes diet plan using a simple checklist record . Participants will be asked to follow their diet plan every day. They are encouraged to create a diet plan that is as close to their current diet as possible. Meal options include make-from-scratch recipes, quick grab-and-go options,and restaurant options. There may be some time involved in learning the recipes and the routine of their new diet. It also may alter their grocery spending and habits somewhat

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard behavioral therapy for weight loss
Description: Participants will be provided guidance on cutting and counting calories, setting goals, reading labels, and portion sizes.
Study: NCT06463821

Intervention type: OTHER
Intervention: observational questionnaires
Description: Patient data were collected from questionnaires.

Intervention type: OTHER
Intervention: observational questionnaires
Description: Patient data were collected from questionnaires.
Study: NCT05304923

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Supraglottic jet oxygenation and ventilation
Description: Supraglottic jet oxygenation and ventilation is conducted using a Wei nasal jet tube (WNJ, Well Lead Medical Co. Ltd, Guangzhou, China) which is connected to a manual jet ventilator (Well Lead Medical Co. Ltd, Guangzhou, China) via its jet port. The initial settings of SJOV are: driving pressure (DP) 15psi, respiratory rate (RR) 20 bpm, inspiratory-to-expiratory (I/E) ratio 1:2, and gas supply 100% oxygen.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Nasal cannula oxygen supply
Description: Oxygen supplementation at 2 liters min-1 is delivered via a nasal cannula
Study: NCT05012449

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthrography-assisted joystick technology.
Description: Arthrography-assisted joystick technology.
Study: NCT06615258

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dynamic Neuromuscular Stabilization based breathing training and pelvic floor muscle training
Description: DNS-based breathing exercises will be taught to the women in this group using tactile biofeedback. To create tactile stimulation, one of the hard sponges placed within a belt will be positioned anteriorly in the inguinal region, and the other posteriorly in the Grynfeltt-Lesshaft triangle region. Breathing training will be provided in 3 different positions: sitting, crawling, and happy baby pose.~Pelvic floor muscle training: PFME will consist of 2 parts: relaxation training for pelvic floor muscles and pelvic floor muscle exercises.~Pelvic floor muscles will be given relaxation training in 3 different relaxation positions (modified butterfly pose, child pose and deep squatting position) suggested by Çeliker Tosun et al. PFME will be taught by the physiotherapist in the side-lying with external coccyx palpation. PFME will be applied in the hook-lying position, sitting position and standing position.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor muscle training
Description: Pelvic floor muscle training: PFME will consist of 2 parts: relaxation training for pelvic floor muscles and pelvic floor muscle exercises. Pelvic floor muscles will be given relaxation training in 3 different relaxation positions (modified butterfly pose, child pose and deep squatting position) suggested by Çeliker Tosun et al. PFME will be taught by the physiotherapist in the side-lying with external coccyx palpation. PFME will be applied in the hook-lying position, sitting position and standing position.
Study: NCT05687188

Intervention type: OTHER
Intervention: Blood Sample Collection
Description: Participants will have 40 mL of blood drawn at baseline/pre-treatment. The study team will aim to have this blood collected at the time of standard of care blood draw if possible.

Intervention type: OTHER
Intervention: Tissue Sample Collection
Description: At the time of tissue biopsy or surgical resection (if applicable) pancreatic tumor tissue, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.

Intervention type: OTHER
Intervention: Data Collection
Description: Participants will complete a study questionnaire at baseline that includes medical history, lifestyle, and family history information.

Intervention type: OTHER
Intervention: Medical Image Collection
Description: Medical images that are obtained during routine care such as computed tomography (CT) scans, magnetic resonance imaging (MRIs) and ultrasounds will be reviewed by the study team throughout the participant's medical care.
Study: NCT06666465

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Operating Room Environment Experienced by Patients Wearing Virtual Reality Glasses Before Surgery The Effect of Surgery Experience on Surgical Fear Level and Care Perceptions
Description: The video, which will be shot for patients to experience the operating environment, will include premedication, an operating room and a post-operative care unit. In the video, the operating room environment will be recorded by the researcher with a voice introduction. The image was shot with a 360-degree camera (Insta 360 One X2), edited with an application program (Insta 360 Studio) and then uploaded to the YouTube VR Pro application as a secret video. The video will be shown to the glasses via an Android phone on the internet via YouTube. People wearing glasses at the screening will be able to look in any direction they want thanks to the 360-degree video. They will be able to watch the video again if they want.
Study: NCT06608875

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Hyper-personalized feedback (HPF intervention)
Description: For lower limb motor rehabilitation, the investigator will employ real-time continuous feedback for movement aspects that are specific to each participant's motor deficit. The feedback will be adapted and tailored to each participant.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hyper-personalized feedback (HPF intervention)
Description: For lower limb motor rehabilitation, the investigator will employ real-time continuous feedback for movement aspects that are specific to each participant's motor deficit. The feedback will be adapted and tailored to each participant.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted auditory stimulation during sleep (TASS verum intervention)
Description: The investigator aim to reactivate rehabilitation- related memories through the presentation of auditory stimuli during sleep with the goal of promoting motor memory consolidation into stable motor commands

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Control targeted auditory stimulation during sleep (TASS sham intervention)
Description: Identical auditory presentation during the motor rehabilitation training, but not during the night (sham promotion memory reactivation)
Study: NCT06618950

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: physical activity
Description: The key factor that distinguishes this study from others is its comprehensive examination of the effects of regular physical activity on late adolescents, not only in terms of physical health but also regarding healthy lifestyle behaviors, self-esteem, and psychological well-being. While other studies typically focus on the benefits of physical activity for physical health, this research considers the broader psychological and social development of adolescents, offering a wider perspective. Additionally, its emphasis on the sustainability of a planned and structured physical activity regimen, along with its approach to transforming physical activity into a lifestyle, represents a significant difference.
Study: NCT06620484

Intervention type: DEVICE
Intervention: Musculoskeletal Ultrasound with elastography
Description: Musculoskeletal Ultrasound with elastography

Intervention type: DEVICE
Intervention: Musculoskeletal Ultrasound with elastography
Description: Musculoskeletal Ultrasound with elastography
Study: NCT06619015

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pramlintide Acetate 1 MG/ML
Description: Symlin (R) (Pramlintide acetate) 1000mcg/ml, will be administered as a continuous infusion at a rate of 15mcg/hour, equivalent to the daily recommended maximum dosage of 360mcg/day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Semaglutide Pen Injector
Description: Semaglutide from 0,25mg/week to 2,4mg/week

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide Pen Injector
Description: Semaglutide from 0,25mg/week to 2,4mg/week

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sodium Chloride 0.9% Inj
Description: Placebo
Study: NCT06619522

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB57643
Description: Given orally
Study: NCT06618222

Intervention type: DEVICE
Intervention: Wingspan stent system
Description: All patients had received Percutaneous transluminal angioplasty and stenting with Wingspan stent system.
Study: NCT06622135

Intervention type: DEVICE
Group type: OTHER
Intervention: Tasso Lancet Device
Description: blood samples will be obtained from all participants using Tasso device
Study: NCT06619600

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: Dapagliflozin 10 mg qd

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo qd
Study: NCT06618352

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simulated indoor overheating exposure
Description: Young adults exposed to a multi-day extreme heat event
Study: NCT06683053

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: empagliflozin
Description: Comparing the benefits of both doses of empagliflozin (10 mg versus 25 mg) in terms of heart ejection fraction and quality of life.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: empagliflozin
Description: Comparing the benefits of both doses of empagliflozin (10 mg versus 25 mg) in terms of heart ejection fraction and quality of life.
Study: NCT05453279

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Delcetravir dry powder inhaler
Description: Placebo dry powder inhaler

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Delcetravir dry powder inhaler
Description: Placebo dry powder inhaler
Study: NCT06619873

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-8080
Description: Medication regimen A~Drug:~600mg, Old process tablets，NPO~Medication regimen B~Drug:~600mg, New process tablets，NPO~Medication regimen C~Drug:~600mg, New process tablets，PC.，low-fat diet~Medication regimen D~Drug:~600mg, New process tablets，PC.，high-fat diet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-8080
Description: Medication regimen A~Drug:~600mg, Old process tablets，NPO~Medication regimen B~Drug:~600mg, New process tablets，NPO~Medication regimen C~Drug:~600mg, New process tablets，PC.，low-fat diet~Medication regimen D~Drug:~600mg, New process tablets，PC.，high-fat diet
Study: NCT05991973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chidamide
Description: In the time window of 30-180 days after transplantation: oral chidamide 10mg twice a week with a total of 96 courses(4 weeks as a course). If the MRD turns positive during treatment, the dose can be increased to a maximum of 20 mg twice a week, and donor lymphocyte infusion (DLI) is also permitted in the case of MRD positivity.
Study: NCT05735457

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A short, animated storytelling video on dietary sodium
Description: Participants in the Intervention Arm will view a short, animated storytelling video on dietary sodium and the risks of cardiovascular disease due to increased intake of sodium.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: A short, animated storytelling attention placebo video
Description: The Attention Placebo Control Arm will view an attention placebo control video, unrelated to the outcomes measured in this trial.
Study: NCT06623864

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: meaningful activities
Description: The intervention proposal will be developed in a module with 27 elderly people, all of them men, with moderate dependence and older, with an average age of 84 years. All of them have multiple medical pathologies with the need for continuous nursing care.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: other activities
Description: The intervention proposal will be developed in a module with 27 elderly people, all of them men, with moderate dependence and older, with an average age of 84 years. All of them have multiple medical pathologies with the need for continuous nursing care.
Study: NCT06622746

Intervention type: PROCEDURE
Intervention: Endoscopic Hand Suturing
Description: Endoscopic Hand Suturing is a technique of the wound closure after advanced endoscopic third-space resections I the upper and lower gastrointestinal tract. In this technique, the needle is held on the opposite side from the tip with the needle holder. The needle is pierced perpendicularly into the tissue at the side of the wound with an appropriate margin, then driven through the tissue with rotation and grasped at the bottom of the defect. The same steps are repeated from the middle of the wound to create a symmetrical structure.
Study: NCT06621589

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutritional Counseling
Description: The intervention involves nutritional counseling aimed at improving dietary habits and overall health to participants. During the 2-month period, participants will receive guidance on nutrition, diet planning, and lifestyle changes tailored to their needs. Assessments of knowledge, attitudes, and health metrics will be conducted before and after the counseling sessions to measure the effectiveness of the intervention
Study: NCT06620393

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: DEX 4 mcg/100 ml at a starting dose of 0.6 mcg/kg/hour and increased by 0.2 mcg/kg/hour every 30 minutes up to final dose of 1.4 mcg/kg/hour.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: NaCl 0.9% 100ml
Study: NCT06621017

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ROSE-010 99 mcg
Description: Sub-cutaneous injection of ROSE-010 solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sub-cutaneous injection of saline solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ROSE-010 150 mcg
Description: Sub-cutaneous injection of ROSE-010 solution
Study: NCT06624098

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Early TIPS
Description: TIPS was performed within 72 hours after the endoscopic hemostasis.
Study: NCT06194747

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality improvement bundle
Description: (1) standardizing BZD default to intranasal or buccal midazolam; (2) targeting initial BZD treatment within 10 minutes of seizure onset; (3) relocating and bundling all administration items needed to the hospital unit medication room; (4) utilizing basic seizure first aid in the initial patient assessment; (5) developing and implementing SE-specific EHR documentation; (6) multidisciplinary QI teams

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality improvement bundle and local PDSA cycles with central support
Description: Sites will implement both the standard QI bundle as well as site-specific PDSA cycles with central data and methods support.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality improvement bundle and local PDSA cycles without central support
Description: Sites will implement both the standard QI bundle as well as site-specific PDSA cycles without central data or methods support.
Study: NCT01581697

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oat bran
Study: NCT06399367

Intervention type: DIAGNOSTIC_TEST
Intervention: MSOT
Description: The MSOT system used consists of a laser in the visible near-infrared and far-infrared wavelength range (660nm-1300nm) and an ultrasonic sensor connected to a computer. Using optical components, the area to be measured is illuminated with ultra-short light pulses of selectable wavelength. The light is absorbed to varying degrees inside the object - depending on the properties of the tissue. The absorption of light leads to local microscopic volume fluctuations and thereby emits pressure waves in the ultrasonic range (photoacoustic effect). MSOT enables non-invasive, non-ionizing 2D imaging with high spatial resolution (80 μm), which enables specific visualization of endogenous tissue pigments such as collagen fibers, fat, melanin, oxyhemoglobin and deoxyhemoglobin.

Intervention type: DIAGNOSTIC_TEST
Intervention: MSOT
Description: The MSOT system used consists of a laser in the visible near-infrared and far-infrared wavelength range (660nm-1300nm) and an ultrasonic sensor connected to a computer. Using optical components, the area to be measured is illuminated with ultra-short light pulses of selectable wavelength. The light is absorbed to varying degrees inside the object - depending on the properties of the tissue. The absorption of light leads to local microscopic volume fluctuations and thereby emits pressure waves in the ultrasonic range (photoacoustic effect). MSOT enables non-invasive, non-ionizing 2D imaging with high spatial resolution (80 μm), which enables specific visualization of endogenous tissue pigments such as collagen fibers, fat, melanin, oxyhemoglobin and deoxyhemoglobin.