TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05336500

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pilates method exercises
Description: Participants will be randomised into two groups that will be treated with Pilates exercises for 12 weeks (twice a week for 60 minutes). The control group will receive guidance on the specific activation of the center of strength (the powerhouse), while the experimental group will receive guidance to perform the exercises in a relaxed and smooth way.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates method exercises
Description: Participants will be randomised into two groups that will be treated with Pilates exercises for 12 weeks (twice a week for 60 minutes). The control group will receive guidance on the specific activation of the center of strength (the powerhouse), while the experimental group will receive guidance to perform the exercises in a relaxed and smooth way.
Study: NCT04485624

Intervention type: OTHER
Intervention: No intervention
Description: Observational study
Study: NCT05427214

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Halcyon 4.0 system
Description: During each of the 1 or more imaging sessions, no more than 6 images total will be acquired. Only 5 images total across all of the imaging sessions will be used toward the study endpoint.
Study: NCT06133348

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promoting Resilience in Stress Management Intervention
Description: PRISM is a manualized, brief, skills-based intervention targeting four resilience resources; PRISM is delivered by trained intervention staff (called coaches within the PRISM program). Session 1, Stress-Management. Session 2, Goal setting. Session 3, Cognitive Restructuring. Session 4, Meaning-Making. Session 5 (optional), Coming Together. Session 6 (optional) involved advance care planning to discuss.
Study: NCT06538402

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 10 cm pouch
Description: A 10 cm pouch will be constructed

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 15 cm pouch
Description: A 15 cm pouch will be constructed
Study: NCT05570058

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RXC007
Description: RXC007 will be administered in the form of oral capsules at 3 potential dose levels: 20 mg, 50mg and 70 mg in 5 cohorts. 12 patients of cohorts 1, 2 and the Expansion cohort will receive RXC007. The Dosage regimen is BID or QD.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RXC007
Description: RXC007 will be administered in the form of oral capsules at 3 potential dose levels: 20 mg, 50mg and 70 mg in 5 cohorts. 12 patients of cohorts 1, 2 and the Expansion cohort will receive RXC007. The Dosage regimen is BID or QD.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RXC007
Description: RXC007 will be administered in the form of oral capsules at 3 potential dose levels: 20 mg, 50mg and 70 mg in 5 cohorts. 12 patients of cohorts 1, 2 and the Expansion cohort will receive RXC007. The Dosage regimen is BID or QD.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: The placebo will be administered in the form of oral capsules at each dose level to 4 of the 16 participants within cohorts 1, 2 and the Expansion cohort. The Dosage regimen is BID or QD

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: The placebo will be administered in the form of oral capsules at each dose level to 4 of the 16 participants within cohorts 1, 2 and the Expansion cohort. The Dosage regimen is BID or QD

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: The placebo will be administered in the form of oral capsules at each dose level to 4 of the 16 participants within cohorts 1, 2 and the Expansion cohort. The Dosage regimen is BID or QD
Study: NCT04520711

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TCR-transduced T cells
Description: TSA-reactive TCR-engineered T cells

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CDX-1140
Description: Recombinant fully human IgG2κ monoclonal antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Humanized immunoglobulin G4 (IgG4) monoclonal antibody
Study: NCT06204393

Intervention type: OTHER
Intervention: Thyroid metabolic index
Description: The following indicators were collected from these patients: hyperthyroidism symptoms, signs, hyperthyroidism complications, psychological evaluation results, other complications，blood routine, liver and kidney function, thyroid function (FT3, FT4, TSH), thyroid-related antibodies, glucose and lipid metabolism (FBG, HbA1c, TC, TG, HDL-C, LDL-C), thyroid ultrasound and hyperthyroidism medication.~Psychological evaluations (using the 7-item Generalized Anxiety Disorder Questionnaire, GAD-7, and the Patient Health Questionnaire 9, PHQ-9) and interventions.

Intervention type: OTHER
Intervention: Thyroid metabolic index
Description: The following indicators were collected from these patients: hyperthyroidism symptoms, signs, hyperthyroidism complications, psychological evaluation results, other complications，blood routine, liver and kidney function, thyroid function (FT3, FT4, TSH), thyroid-related antibodies, glucose and lipid metabolism (FBG, HbA1c, TC, TG, HDL-C, LDL-C), thyroid ultrasound and hyperthyroidism medication.~Psychological evaluations (using the 7-item Generalized Anxiety Disorder Questionnaire, GAD-7, and the Patient Health Questionnaire 9, PHQ-9) and interventions.

Intervention type: OTHER
Intervention: Thyroid metabolic index
Description: The following indicators were collected from these patients: hyperthyroidism symptoms, signs, hyperthyroidism complications, psychological evaluation results, other complications，blood routine, liver and kidney function, thyroid function (FT3, FT4, TSH), thyroid-related antibodies, glucose and lipid metabolism (FBG, HbA1c, TC, TG, HDL-C, LDL-C), thyroid ultrasound and hyperthyroidism medication.~Psychological evaluations (using the 7-item Generalized Anxiety Disorder Questionnaire, GAD-7, and the Patient Health Questionnaire 9, PHQ-9) and interventions.
Study: NCT06572085

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Butylphthalide and Sodium Chloride Injection
Description: All enrolled patients will undergo standard treatment as per international guidelines, concurrently receiving either NBP or placebo therapy. Patients in the experimental group will receive intravenous infusion of 100ml NBP injection twice daily, while patients in the control group will receive intravenous infusion of 100ml saline solution twice daily. Each patient will receive continuous medication for 14 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline Solution
Description: All enrolled patients will undergo standard treatment as per international guidelines, concurrently receiving either NBP or placebo therapy. Patients in the experimental group will receive intravenous infusion of 100ml NBP injection twice daily, while patients in the control group will receive intravenous infusion of 100ml saline solution twice daily. Each patient will receive continuous medication for 14 days.
Study: NCT06572007

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: To investigate the thickness of the fascia tissue, the subjects will undergo an ultrasound examination using a clinical ultrasound system (S9, SonoScape Corporation, made in China) with a linear 5-14 MHz array of L14-5/38. The transducer with a cross-section of 6.24 cm2 will be aimed at points 2 cm lateral to the midline of the L2 and L3 vertebrae on both sides of the spine.
Study: NCT06238505

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual
Description: application will be made with virtual reality device

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: biodex
Description: application will be made with biodex device
Study: NCT04713748

Intervention type: DEVICE
Group type: OTHER
Intervention: Tasso-SST on Demand
Description: Participants will collect a small blood sample using the Tasso-SST OnDemand device during a serology blood draw visit already scheduled for the MURDOCK C3PI Study (Pro00105703). Participants will be provided a kit that includes written, step-by-step instructions that include pictures. Participants will also have the option to watch a brief video on using the device, available online, prior to collection. Both blood samples will be spun and processed for serum. Serum will be frozen and shipped to the lab at Duke for antibody testing. Antibody results will be compared between the two methods.

Intervention type: OTHER
Group type: OTHER
Intervention: Regular Phlebotomy
Description: Participants will have a small blood sample collected via regular venipuncture.
Study: NCT04690608

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone Acetonide 40Mg/Ml Inj,Susp_#1
Description: suprachoroidal injection of the drug in cases of resistant diabetic macular edema and central retinal vein occlusion
Study: NCT05247918

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital-physical care
Description: Patients will get access to a digital communication platform. Two in person session and two digital contacts per year with possibility to chat with caregivers in between.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: Four in person session at the center in a year.
Study: NCT06136520

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baby massage
Description: After the first measurements are made and the groups are determined; Personal Information Form, Perinatal Attachment Inventory and Beck Depression Inventory will be applied to the experimental and control groups. Pregnant women in the experimental group were 32-40 weeks of pregnancy.~After baby massage training is given, 30-42 weeks after birth. between days and 60-72. Maternal Attachment Scale and Edinburgh Postpartum Depression Scale will be applied to the experimental and control groups on the following days. The control group will receive standard care while the experimental group receives training. After the second postpartum data of the pregnant women in the control group are collected, a 30-minute baby massage training will be given by the researcher.
Study: NCT06142812

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kahoot!™ Group
Description: The theoretical concepts of each subject were taught over a period of four months, with a total duration of 30 hours. Of the total theoretical concepts of the subject, 50% were randomly selected to receive reinforcement through Kahoot! Each of the theoretical concepts chosen at random was consolidated through a Kahoot! questionnaire. which consisted of 15 questions, with three answer options. This questionnaire was administered at the end of the theoretical explanation of each section, with the objective of strengthening the learning of the contents just presented. After students answered each question in Kahoot!, the teacher clarified any questions related to that question and provided explanations as to why one answer was correct and the other two were incorrect. This process offered immediate feedback to students.
Study: NCT05572242

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Premolar extraction and socked preservation with L-PRF
Description: Partially edentulous patients in need of a single-tooth extraction in the premolar region\[ (maxilla or mandible), with two neighboring natural teeth, will be included in the study. The tooth will be luxated first with elevators and then carefully extracted with forceps without raising a flap.~L-PRF group will use 2-5 PRF clots, depending on the size of the socket, which will be inserted and compressed with a large plunger until they reach the alveolar crest. The site will thereafter be covered with L-PRF membranes. Then, crossed horizontal mattress suture will be placed followed by single interrupted sutures for stabilization. No efforts will be undertaken to obtain primary wound closure. The grafted socket will be left to heal for 4 months.~After 4 months of socket preservation, a dental implant will be inserted into the socket. After 4 months of implant healing, a cad cam final restoration will be delivered. The follow-up will be up to 12 months after the final restoration.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Premolar extraction and socked preservation with Xenogenic bone and collagen membrane.
Description: Partially edentulous patients in need of a single-tooth extraction in the premolar region (maxilla or mandible), with two neighboring natural teeth, will be included in the study. The tooth will be luxated first with straight and angled elevators and then carefully extracted with forceps without raising a flap.~In the control group, the socket will be grafted with xenogeneic bone substitute material (up to the palatal/lingual bone crest) and covered with a collagen matrix. Single interrupted sutures will be placed to stabilize the collagen matrix. Sutures will be removed at 7-10 days. The grafted socket will then be left to heal for a period of 4 months.~The xenogenic material will be Bio-Oss Collagen® and collagen matrix Bio-Gide® .~After 4 months of socket preservation, a dental implant will be placed. After 4 months of implant healing, a cad cam final restoration will be delivered. The follow-up will be up to 12 months after the final restoration.
Study: NCT05886764

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Intervention
Description: Digital messages (email, text, etc.) which include general educational information about clinical trials and available resources.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Intervention
Description: Digital messages (email, text, etc.) which include general educational information about clinical trials and available resources.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Community Outreach
Description: Invitation to contact a Community Ambassador for further information and support in the decision to participate in a clinical trial.
Study: NCT05120544

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EXTEND Plus
Description: The EXTEND Plus approach builds patient self-management capacity by focusing on knowledge, self-efficacy, and goal setting (using an RN-delivered, module-based approach). All material is at an 8th grade reading level. Module topics include, but are not limited to, use of self-monitoring of blood glucose (SMBG), BP monitoring, developing a diet plan, medication adherence, hypoglycemia and hypotension self-management, and self-managing insulin. In addition, this intervention component addresses diet and activity self-management during each encounter.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: EXTEND
Description: EXTEND patients self-manage using data they collect during the study, and continue to receive standard behavioral counseling from primary providers.
Study: NCT05229224

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteo fluidic Sensitive méthod
Description: Manual therapy, without manipulative treatment, based on rebalancing of the body with manual pressures on specific body areas.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo method
Description: Soft Manual pressures at specific points that are defined as non-effective and non-deleterious for patients.
Study: NCT06573060

Intervention type: DEVICE
Intervention: Continuous glucose monitoring
Description: Subjects with T2DM and acute coronary syndrome (n=120) were fitted with continuous glucose monitors (CGM) to closely monitor their blood glucose levels continuously for 14 days.
Study: NCT06078397

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote programming
Description: Remote programming (RP) is a new type of patient management method after DBS surgery, which allows physicians to understand the patient's movement symptoms and adjust parameters through video conferencing. At the same time, the RP system also includes device checks, medication adjustments, psychological counseling, and other contents. Compared to standard programming that requires going to the hospital, the application of RP can save the burden on patients and their caregivers.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: standard programming
Description: Programming refers to a series of methods that set the parameters of the IPG after the implantation of DBS, and adjust the device parameters based on the patient's symptoms during subsequent follow-up to maintain the efficacy of electrical stimulation.
Study: NCT05966025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itopride
Description: itopride will be taken by pateints one time per day by dose 100 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: conventional therapy
Description: will taken by patient in control group

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: conventional therapy
Description: will taken by patient in control group
Study: NCT04140149

Intervention type: BEHAVIORAL
Intervention: Living with Hope
Description: 12-week, CBT-based, psychoeducational skills class
Study: NCT06165744

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: UNITY VCS
Description: Investigational device used during anterior and posterior segment ophthalmic surgery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Eye surgery
Description: Eye surgery performed with UNITY VCS
Study: NCT04304001

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community Health Advisor
Description: Intervention arm participants will receive one 45-minute face-to-face meeting followed by two phone calls in one-week intervals over a period of three weeks beginning within one month following baseline survey completion. These educational activities will include the use of National Cancer Institute colorectal cancer resources and materials, including a Screen to Save media presentation, and colorectal cancer brochures. The intervention will follow a conversation guide/standard script for intervention fidelity. Community Health Advisors will take notes following each interaction to document the call length and call details. Participants will receive an additional text message reminder once a week for an additional three weeks - with instructions for participants to text yes to confirm they received the message - for a total of six weeks of intervention delivery. The personalized text messages will include short messages about the benefits of colorectal cancer screening.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Control arm participants will receive a Fecal Immunochemical Test kit, a mailed targeted colorectal cancer brochure, and complete a follow-up telephone survey at 3- and 12-months after the mailing.
Study: NCT06023095

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3502970
Description: Administered orally.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally.
Study: NCT06350864

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High-flow nasal cannula (HFNC)
Description: high flow cartridge and adult size nasal cannula: (flow range: 5-40L/minute, oxygen concentration (FiO2): 21-100%, temperature range: 33-39◦ C, humidity minimum of 12mg/liter)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional nasal oxygen therapy (COT)
Description: Adult size, single use nasal cannula

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Upper gastrointestinal endoscopy (UGE) including gastroscopy
Description: Upper gastrointestinal endoscopy (UGE) will be either diagnostic and/or therapeutic including variceal band ligation, endoscopic hemostasis as injection of bleeding peptic ulcers with adrenaline or bleeders control via either argon plasma coagulation (APC) or heater probe coagulation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Upper gastrointestinal endoscopy (UGE) including gastroscopy
Description: Upper gastrointestinal endoscopy (UGE) will be either diagnostic and/or therapeutic including variceal band ligation, endoscopic hemostasis as injection of bleeding peptic ulcers with adrenaline or bleeders control via either argon plasma coagulation (APC) or heater probe coagulation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Upper gastrointestinal endoscopy (UGE) including Endoscopic ultrasound (EUA)
Description: Upper gastrointestinal endoscopy (UGE) will be diagnostic

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Upper gastrointestinal endoscopy (UGE) including Endoscopic ultrasound (EUA)
Description: Upper gastrointestinal endoscopy (UGE) will be diagnostic
Study: NCT06216236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinect intervention system combined with aerobic exercise training
Description: A Kinect intervention system was used in the experimental group. The video displayed a skeletal simulation of the action. The participants could see their own actions and those of the teacher. After the video was completed, an accurate score for each action was displayed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aerobic dance training
Description: The control group used a video that did not show a skeletal simulation of the action and only saw the teachers movements.
Study: NCT05500976

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Semi-controlled dietary intervention - Western
Description: Participants will complete a 2-week washout prior to a 16-week randomized, crossover semi-controlled feeding study of mini-MED vs Western diet. Each diet intervention will last four weeks, with 500 kcal/day of target Western diet foods (eg, beef, potatoes, bread, sour cream) provided during each intervention and will be repeated twice.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Semi-controlled dietary intervention - MiniMed
Description: Participants will complete a 2-week washout prior to a 16-week randomized, crossover semi-controlled feeding study of mini-MED vs Western diet. Each diet intervention will last four weeks, with 500 kcal/day of target Mediterranean foods (eg, oatmeal, salmon, nuts, basil, olive oil, fruits) provided during each intervention and will be repeated twice.