TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06368570

Intervention type: OTHER
Intervention: Interview
Description: Patients will be interviewed by the research team to learn about their experience of Cesarean delivery with neuraxial anesthetic
Study: NCT05715697

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham procedure and maintenance of heart failure medications
Description: Sham intervention, maintenance of heart failure medications

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Renal denervation and maintenance of heart failure medications
Description: Renal denervation and maintenance of heart failure medications
Study: NCT04751526

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BreEStim 240
Description: 240 BreEStim stimuli/visit will be applied for 10 sessions to test any accumulated analgesic effect.
Study: NCT05784857

Intervention type: OTHER
Group type: OTHER
Intervention: Touch Methods
Description: The Yakson touch method continue for 15 minutes with steady touch (5 minutes), compassionate caressing (5 minutes), and repetition of steady touch (5 minutes). In this method, the palms of the practitioner and all fingers keep in close contact so that the babies don't feel pressure.~Gentle human touch refers to steady contact of the skin without caressing or massaging. While the practitioner place one hand on the crown of the preterm infant on the eyebrow line with the fingertip touch for 15 minutes, the other hand was place on the lower abdomen covering the waist and hip of the infants.
Study: NCT04751526

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EStim 240
Description: 240 EStim stimuli/visit will be applied for 10 sessions to test any accumulated analgesic effect.
Study: NCT05412615

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Meniscus Allograft Transplantation with Proximal Row Carpectomy
Description: Supplementing the wrist reconstruction with a meniscal allograft to improve wrist function and pain scores.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Proximal Row Carpectomy
Description: Standard proximal row carpectomy with no tissue or synthetic adjuncts
Study: NCT04803006

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TCD601
Description: Investigational Product

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TCD601
Description: Investigational Product
Study: NCT05829876

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Frequency ECG Mapping
Description: A high frequency ECG map will be performed to assess the optimum left ventricular pacing site.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Q-LV Measurement
Description: Measurement of Q wave on 12 lead ECG to LV stimulus to assess optimum left ventricular pacing site.
Study: NCT05288556

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Placement of stoma site enteral feeding tube accessory
Description: The study stoma site accessory will be attached at the stoma site during an enteral tube replacement procedure the patient is scheduled to have as a standard of care procedure. The study stoma site accessory is compatible with commercially available enteral nutrition feeding tubes ranging from size 16 to 20 French tubing that are adjustable to variable length.
Study: NCT06563843

Intervention type: PROCEDURE
Intervention: Robotic-assisted TKA
Description: Robotic-assisted Total Knee Arthroplasty or total knee replacement is a surgical procedure using a robot to resurface a knee joint damaged with arthritis, and where the knee joint of the patient is replaced with a prosthesis.

Intervention type: PROCEDURE
Intervention: Conventional TKA
Description: Conventional Total Knee Arthroplasty or total knee replacement is a surgical procedure to manually resurface a knee joint damaged with arthritis, and where the knee joint of the patient is replaced with a prosthesis.
Study: NCT05390788

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Application Of Neuromuscular Bands; Kinesio Taping
Description: Kinesio tape is a specialized elastic and adherent adhesive tape that mimics the elasticity of skeletal muscle, in that it can be extended up to 140% of its original length, before application to the skin, without allowing restrictions in the range of motion. of structures. Subsequently, it provides a tensile (shear) force on the skin, consisting of a fabric with special characteristics, such as air permeability and water resistance, and can be used for repeated days. Kinesio will be applied from a point 10 cm below the anterior superior iliac spine and divided in a Y shape above the patella, ending at the tibial tuberosity; from the upper third of the medial thigh to the medial border of the patella; from the greater trochanter of the femur, ending at the lateral margin of the patella.
Study: NCT05626803

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Open label Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose
Description: The first 10 sentinel subjects will receive open label high dose of active vaccine. Bivalent GII.4/GI.1 high dose vaccine (VXA-GII.4-NS plus VXA-G1.1-NN) 1×10 to the power 11 tablets; total dose is 2×10 to the power 11 IU/dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose
Description: 50 subjects will receive high dose of active vaccine. Bivalent GII.4/GI.1 high dose vaccine (VXA-GII.4-NS plus VXA-G1.1-NN) 1×10 to the power 11 tablets; total dose is 2×10 to the power 11 IU/dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bivalent GII.4/GI.1 medium dose vaccine 1×10 to the power 11 IU/dose
Description: 50 subjects will receive Bivalent GII.4/GI.1 medium dose vaccine (VXA-GII.4-NS plus VXA-G1.1-NN) 5×10 to the power 10 tablets; total dose is 1×10 to the power 11 IU/dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 25 subjects will receive matching placebo
Study: NCT05740514

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Exercise training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Exercise training.
Study: NCT05643157

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Adaptive Optics - Optical Coherence Tomography (AO-OCT) retinal imaging
Description: AO-OCT used in this study is an investigational OCT imaging system. . In this instrument, ocular aberration sensing and correction is achieved with a Shack-Hartmann wavefront sensor (SHWS) and deformable mirror, respectively. A pupil camera and fixation target are used to position the participant's head and eye for scanning a particular retinal region within 15 degrees of the fovea. Data collected generally includes AO-OCT volume videos and SHWS measurements of ocular aberrations.
Study: NCT05257135

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological collection
Description: - Blood samples collected at different times: at inclusion and during treatment ( every 6 month)
Study: NCT05740514

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: De-training
Description: Exercise de-training via unilateral knee immobilization.
Study: NCT05453214

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludrocortisone Acetate 0.1 MG
Description: Fludrocortisone acetate 0.1 mg tablet / 12 hours; dose to be titrated according to response.
Study: NCT05126745

Intervention type: DEVICE
Intervention: color flow Doppler ultrasonography
Description: Doppler ultrasonography
Study: NCT06418126

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood sampling before radiotherapy
Description: A blood sample (20 ml) will be taken prior to radiotherapy

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood sampling after the fourth radiotherapy session
Description: A blood sample (20 ml) will be taken immediately after the 4th radiotherapy session.
Study: NCT06229691

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 30 minute treadmill walk
Description: Participants will walk on a treadmill at their preferred speed for 30 minutes. One minute challenge periods will occur at minutes 7, 17, and 27, when the treadmill speed will increase by 50%. This walk will induce a magnitude of muscle fatigue corresponding to an individual participant's fatigability.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 30 minute treadmill walk
Description: Participants will walk on a treadmill at their preferred speed for 30 minutes. One minute challenge periods will occur at minutes 7, 17, and 27, when the treadmill speed will increase by 50%. This walk will induce a magnitude of muscle fatigue corresponding to an individual participant's fatigability.
Study: NCT05227170

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lactobacillus Plantarum 299v Freeze Dried Capsule
Description: The intervention is a probiotic lactobacillus that is contained in food products in the US

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Freeze Dried Potato Starch Capsule
Description: The intervention is potato starch that is freeze dried designed to mimic the lp299v capsule.
Study: NCT06033287

Intervention type: DRUG
Intervention: Different treatment regimens following progression on CDK4/6 inhibitors.
Description: This study is a single-arm, non-interventional study that evaluates the efficacy and safety of the first-line treatment regimen, which includes CDK4/6 inhibitors combined with endocrine therapy. After disease progression on first-line treatment, the second-line systemic treatment regimen (including but not limited to switching to another CDK4/6 inhibitor combined with endocrine therapy, other types of endocrine therapy, chemotherapy, targeted therapy, etc.) will be evaluated.
Study: NCT04998851

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ocrelizumab
Description: Women will receive the ocrelizumab dose regimen as per the locally-approved label. The ocrelizumab dose will be administered as an initial split dose of two 300 mg infusions separated by 14 days or a single 600 mg infusion according to the local prescribing information.
Study: NCT06418126

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of acute toxicity (radiodermatitis)
Description: for the entire duration of radiotherapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of late toxicity
Description: every year for 5 years

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of disease status
Description: throughout the study

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy - Breast +/- lymph node areas
Description: 40.05 Gy in 15 fractions of 2.67 Gy, one fraction per week, 5 days per week Or 50 Gy in 25 fractions of 2 Gy, one fraction per week, 5 days per week
Study: NCT05407701

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Cranberry Juice
Description: 100% cranberry juice

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo juice
Study: NCT06418126

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy - Boost operating bed
Description: 10 Gy in 4 fractions of 2.5 Gy, one fraction per week, 5 days per week Or 16 Gy in 8 fractions of 2 Gy, one fraction per week, 5 days per week
Study: NCT05186909

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM310
Description: CM310 Recombinant Humanized Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM310
Description: CM310 Recombinant Humanized Monoclonal Antibody Injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05701488

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Intravenous infusion
Study: NCT04244682

Intervention type: DEVICE
Group type: OTHER
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: In the rTMS procedure a small plastic coil will be placed next to the participant's head. The position of the coil will be guided by neuro-navigational software utilizing the individual's MRI scan. The coil will be placed over the relevant brain region using the Brainsight TMS-MRI co-registration system for visualizing the coil position with respect to the participant's individual MRI scan. The coil will then generate a series of repetitive magnetic pulses, and stimulation will occur, disrupting typical function of the targeted brain region.
Study: NCT05701488

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SIRT
Description: SIR (Selective Internal Radiation) Sphere resin microspheres, radioactive particles delivered via injection into an artery.
Study: NCT06240715

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Umbilical cord milking
Description: At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 1--15 seconds.
Study: NCT05895734

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NDS-Powerball®,
Description: Rehabilitation using the Powerball system

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Rehabilitation by conventional treatment
Study: NCT05793814

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Limosilactobacillus reuteri 3613
Description: Daily for 6 month

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Daily for 6 month
Study: NCT06454851

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prosocial VR intervention
Description: A four-week gamified prosocial VR intervention program based on literature review and relevance to the local contexts will be developed for the proposed project. The intervention will be expanded to include four weekly sessions, each lasting between 15 to 20 minutes. Each session will depict a different daily life scenario-campus, lecture hall, canteen, and library, respectively. During each session, participants will engage in a series of tasks that incorporate elements of prosocial behavior or helping actions within the scene. These tasks are designed to be more comprehensive and interactive, ensuring that participants are fully immersed in the experience for the entire duration of the session.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: No intervention
Description: The waitlist control group will not receive the intervention during the study.
Study: NCT05551338

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Serious games
Description: The training protocol will entail using a tablet-based program that includes 6 serious games. Patients will be asked to use the program twice a week for 3 months. The serious games that will be used in this study were developed to challenge short-term memory and selective attention in six different games. Each of the six games comprise 20 different stages of varying difficulty, where stage 1 is the easiest and stage 20 is the most difficult.
Study: NCT05204511

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: endurance training
Description: endurance training of low to moderate intensity on a bicycle ergometer, crosstrainer or treadmill performed for 30-60 minutes per session

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: concurrent training
Description: combination of endurance training of low to moderate intensity on a bicycle ergometer, crosstrainer or treadmill performed for 20-40 minutes per session and resistance training of moderate intensity performing 2-3 sets of leg press, leg curls, chest press and seated horizontal rows
Study: NCT05442242

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Unicompartmental knee arthroplasty
Description: Medial Unicompartmental knee arthroplasty

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High tibial osteotomy
Description: Medial open wedge high tibial osteotomy
Study: NCT06191120

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: [18F]-ALF-FAPI-74 PET/CT scan
Description: Participants will receive up to three \[18F\]-ALF-FAPI-74 PET/CT scans. \[18F\]-ALF-FAPI-74 is a PET tracer with high binding specificity and selectivity to FAP-expressing cells.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: [18F]-ALF-FAPI-74 PET/CT scan
Description: Participants will receive up to three \[18F\]-ALF-FAPI-74 PET/CT scans. \[18F\]-ALF-FAPI-74 is a PET tracer with high binding specificity and selectivity to FAP-expressing cells.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: [18F]-ALF-FAPI-74 PET/CT scan
Description: Participants will receive up to three \[18F\]-ALF-FAPI-74 PET/CT scans. \[18F\]-ALF-FAPI-74 is a PET tracer with high binding specificity and selectivity to FAP-expressing cells.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: [18F]-ALF-FAPI-74 PET/CT scan
Description: Participants will receive up to three \[18F\]-ALF-FAPI-74 PET/CT scans. \[18F\]-ALF-FAPI-74 is a PET tracer with high binding specificity and selectivity to FAP-expressing cells.
Study: NCT06405698

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: surgical closure of myelomeningocele defects by perforator flaps
Description: closure of myelomeningocele defect by perforator island flap after complete incision of the flap all around based on perforator vessel .
Study: NCT06271824

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Compassion Based Resilient Caregiving Course
Description: The Resilience Habits for Caregivers Course is a live, online, weekly 6 session program lasting 1.5 hours per session. The structure contains didactics, group discussions, guided exercises, and practices facilitated by a certified self-compassion instructor. Topics covered include: (1) noticing and accepting emotions (including conflicting emotions); (2) cultivating curiosity and self-compassion; (3) relating skillfully to difficult thoughts; (4) savoring and gratitude practices.
Study: NCT05261880

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neural mobilization
Description: Neural mobilization and bone are two common physical therapy interventions used for Carpal Tunnel Syndrome. Neural mobilization reinstates the plasticity of the nervous system and restoring the capacity of stretching.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scaphoid , hamate mobilization
Description: Bone mobilization in Carpal Tunnel Syndrome involves gliding at scaphoid and hamate.
Study: NCT05534893

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Blueberry powder group
Description: Participants in the blueberry powder group will receive freeze dried blueberries in form of a powder

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Blueberry powder group
Description: Participants in the blueberry powder group will receive freeze dried blueberries in form of a powder
Study: NCT05580471

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use 4DryField
Description: Patients randomly use 4DryField in Colorectal resection combined with temporary stomy before fascia closure. We observed the adhesion severity and adhesion extent when stomy closure.
Study: NCT05534893

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo powder group
Description: Participants in the placebo powder group will receive an isocaloric placebo powder

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo powder group
Description: Participants in the placebo powder group will receive an isocaloric placebo powder
Study: NCT02637986

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Urex Plus - containing L. rhamnosus GR-1 and L. reuteri RC-14
Description: 2 capsules will be given per day
Study: NCT05254314

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide Pen Injector 2.4mg weekly
Description: Once weekly subcutaneous injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Once weekly subcutaneous injection
Study: NCT04307303

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: abdominal functional electrical stimulation
Description: functional electrical stimulation of the abdominal muscles

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: abdominal functional electrical stimulation
Description: functional electrical stimulation of the abdominal muscles
Study: NCT06068322

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise training on a stationary bicycle
Description: Training is performed two to three times per week for a total of 30 sessions using a group format.~Both regimens start with a five-minute warm-up and ends with a five-minute cool-down, performed at an intensity corresponding to 30% of the maximal work rate achieved during a CPET (i.e., max aerobic power \[MAP\]) with a self-selected pedalling cadence of 50-70 revolutions per minute (RPM).~All exercise sessions will be held and supervised by an experienced health care professional, i.e. physiotherapists or other health professional.~The different types of exercise training is described under the specific arm.~Following the first 12-week training period, participants with COPD will enter a 21-month maintenance phase. They will continue to exercise using the same training modality (HIIT or MICT) as during the first 12-weeks but can select between three different settings to continue their training: Home, Outpatient, or Mix setting.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise training on a stationary bicycle
Description: Training is performed two to three times per week for a total of 30 sessions using a group format.~Both regimens start with a five-minute warm-up and ends with a five-minute cool-down, performed at an intensity corresponding to 30% of the maximal work rate achieved during a CPET (i.e., max aerobic power \[MAP\]) with a self-selected pedalling cadence of 50-70 revolutions per minute (RPM).~All exercise sessions will be held and supervised by an experienced health care professional, i.e. physiotherapists or other health professional.~The different types of exercise training is described under the specific arm.~Following the first 12-week training period, participants with COPD will enter a 21-month maintenance phase. They will continue to exercise using the same training modality (HIIT or MICT) as during the first 12-weeks but can select between three different settings to continue their training: Home, Outpatient, or Mix setting.
Study: NCT04876599

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IN FOCUS
Description: Adapted Resiliency Group Intervention

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Referral to Virtual Group Support