TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06318559

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 3D Robot-assisted laparoscopic radical prostatectomy and pelvic lymphadenectomy
Description: The operation is performed using the Da Vinci HD robotic system which allows the use of laparoscopic instruments, with greater mobility and the possibility of easier and more precise control of movements in three dimensions. Furthermore, the system allows the surgeon a three-dimensional view of the operating field. The surgery is performed under general anesthesia. Six or more trocars are positioned, into which the instruments operated by the robot or directly by the surgical assistants are inserted.~Then a radical prostatectomy is performed.
Study: NCT06125626

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotical
Description: A daily sachet of Lacticaseibacillus rhamnosus LR04 + Streptococcus thermophilus FP4 + Bifidobacterium breve BR03 will be given to this group

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A daily sachet of placebo will be given to this groups
Study: NCT05763472

Intervention type: GENETIC
Intervention: Next-generation sequencing (NGS) assay TruSight Oncology 500 (TSO 500).
Description: Next-generation sequencing (NGS) analysis with TruSight Oncology 500 (TSO 500) is performed on tumor samples from breast and ovarian cancer of the enrolled patients.
Study: NCT06038968

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate 25 MG/ML
Description: Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: parsplana vitrectomy
Description: Pars plana vitrectomy (PPV) is a technique in vitreoretinal surgery that enables access to the posterior segment for treating tractional retinal detachment in advanced proliferative diabetic retinopathy, in a controlled, closed system.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: parsplana vitrectomy
Description: Pars plana vitrectomy (PPV) is a technique in vitreoretinal surgery that enables access to the posterior segment for treating tractional retinal detachment in advanced proliferative diabetic retinopathy, in a controlled, closed system.
Study: NCT06237361

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercises
Description: participants underwent a 12-week intervention involving three Pilates sessions per week. The Pilates exercises comprised warm-up activities, Pilates routines, and cool-down exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional physical therapy program
Description: The program included a variety of exercises such as range of motion exercises, aerobic exercises, resistance exercises, scar management, occupational therapy, and hand therapy.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional physical therapy program
Description: The program included a variety of exercises such as range of motion exercises, aerobic exercises, resistance exercises, scar management, occupational therapy, and hand therapy.
Study: NCT05026892

Intervention type: OTHER
Intervention: no intervention
Description: no intervention, only collection of data

Intervention type: OTHER
Intervention: no intervention
Description: no intervention, only collection of data
Study: NCT04465721

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TRE
Description: The TRE intervention will be administered and monitored via the study app. It combines self-monitoring behavior, daily eating window reminders, positive reinforcement based on number of log entries or based on meeting eating widow target, and basic lifestyle text messages. It also allows research staff to monitor in real-time, via the backend cloud, adherence to self-monitoring, and to reducing the eating window.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HABIT
Description: The HABIT intervention will be administered and monitored via the study app. It combines self-monitoring behavior, positive reinforcement based on number of log entries, and basic lifestyle text messages. It also allows research staff to monitor in real-time, via the backend cloud, adherence to self-monitoring.
Study: NCT06127108

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Panbio™
Description: The Panbio™ COVID-19/Flu A\&B Panel is a visual lateral flow in vitro immunoassay for the qualitative detection of the nucleocapsid protein antigen to SARS-CoV-2, Influenza A, and Influenza B in anterior nasal swab samples from individuals with symptoms and suspected of COVID-19 or Flu infection by their healthcare provider.
Study: NCT06140550

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Drug balloon dilated
Description: Through the expansion after the balloon is in place,Release drugs on the surface of the balloon and improve the blood perfusion of nerve vessels to treat stenosis
Study: NCT05853926

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation With Laser Therapy
Description: Spinal Manipulation With Laser Therapy in Chronic Lower Backache

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Dry Needling
Description: Dry Needling in Chronic Lower Backache
Study: NCT06140550

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: balloon dilated
Description: Through the expansion after the balloon is in place, improve the blood perfusion of nerve vessels to treat stenosis.
Study: NCT05900466

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: 500 mg Metformin ER tablets once daily in the morning for 8 weeks
Study: NCT06366854

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Personalised fluid and haemodynamic resuscitation
Description: individualised resuscitation
Study: NCT05900466

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching tablets once daily in the morning for 8 weeks
Study: NCT06041932

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carvedilol
Description: Carvedilol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carvedilol
Description: Carvedilol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline
Description: Pentoxiphylline
Study: NCT04565652

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Device Wearers
Description: The intervention arm will wear the LOIS ICD Smartband during routine ICD defibrillation following elective ICD implant.
Study: NCT05443698

Intervention type: DEVICE
Group type: OTHER
Intervention: Transvaginal ultrasound
Description: Adult women in the U.S. who are eligible for the ultrasound trial on the basis of the inclusion/exclusion criteria will complete an at home transvaginal ultrasound guided by real-time remote supervision from a qualified and specially trained ultrasound technologist.
Study: NCT03894306

Intervention type: OTHER
Intervention: Medication lock box
Description: given a lock box and instructed on how to use the device.

Intervention type: OTHER
Intervention: medication lock bag
Description: given a lock bag and instructed on how to use the device.

Intervention type: OTHER
Intervention: brief counseling
Description: After completing the per-intervention survey, a research assistant or investigator will perform brief counseling, including educational handouts and information on safe medication storage

Intervention type: OTHER
Intervention: brief counseling
Description: After completing the per-intervention survey, a research assistant or investigator will perform brief counseling, including educational handouts and information on safe medication storage

Intervention type: OTHER
Intervention: brief counseling
Description: After completing the per-intervention survey, a research assistant or investigator will perform brief counseling, including educational handouts and information on safe medication storage
Study: NCT04882826

Intervention type: DRUG
Group type: OTHER
Intervention: Sildenafil film-coated tablet 100 mg
Description: Sildenafil is manufactured by Pharmtechnology LLC, Belarus. Each tablet contains 100 mg of sildenafil.

Intervention type: DRUG
Group type: OTHER
Intervention: Sildenafil film-coated tablet 100 mg
Description: Sildenafil is manufactured by Pharmtechnology LLC, Belarus. Each tablet contains 100 mg of sildenafil.

Intervention type: DRUG
Group type: OTHER
Intervention: Viagra® film-coated tablet 100 mg
Description: Viagra® is manufactured by Fareva Amboise, France. Each tablet contains 100 mg of sildenafil.

Intervention type: DRUG
Group type: OTHER
Intervention: Viagra® film-coated tablet 100 mg
Description: Viagra® is manufactured by Fareva Amboise, France. Each tablet contains 100 mg of sildenafil.
Study: NCT04951479

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gel-Bead embolization
Description: OptiSphere is FDA approved for the embolization of hypervascular tumors. The product is crosslinked with glutaraldehyde, which improves the mechanical strength of the spheres and provides controlled degradation after implant. The spherical shape provides smooth embolic delivery and even, predictable distribution. In this study the Optispheres will be used for Geniculate artery embolization (GAE) which is a minimally-invasive procedure that has historically been performed for treatment of patients with recurrent knee hemarthrosis. Embolization is a procedure in which material is used to block small blood vessels. Angiogenesis, or growth of new vessels, has been implicated in the initiation and maintenance of joint inflammation. GAE has been applied to patients with moderate osteoarthritis-related pain refractory to maximal medical management with preliminary studies demonstrating a reduction in patient pain.
Study: NCT06466083

Intervention type: OTHER
Intervention: no intervention
Description: this is an observation study,no intervention
Study: NCT05492799

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AX 250
Description: biweekly infusion by intracerebroventricular (ICV) infusion
Study: NCT04662073

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camostat
Description: 200 mg (2 x 100 mg tablet) administered orally four times daily (800 mg total daily dose).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match camostat administered orally four times daily
Study: NCT04844203

Intervention type: DIAGNOSTIC_TEST
Intervention: Polygraphy with surface electrodes
Description: Patients referred for ENMG to the Clinical Physiology Department and complaining of postural unsteadiness will undergo a polygraphy recording using surface electrodes (Natus Medical Incorporated), performed at the end of ENMG
Study: NCT05761678

Intervention type: OTHER
Intervention: Questionnaire quality of life
Description: Quantitative - Validated online self-questionnaires scientifically to assess quality of life and support perceived social. Items created for the study concerning socio-demographic characteristics and satisfaction of health services concerning the accompaniment of the transidentity.~Qualitative - Semi-structured interviews based on a guide maintenance.
Study: NCT04757688

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Cardiac radioablation (CRA)
Description: CRA to 25 Gy in 1 fraction
Study: NCT06146634

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hazard Perception Training
Description: The hazard perception training is comprised of three modules. Each module is comprised of four scenarios. Each hazard perception scenario has two activities. The entire training is expected to take approximately an hour to complete.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Maintenance Training
Description: For participants randomized into the placebo group, they will receive a brief training on vehicle maintenance using a series of short videos. These videos describe regular checks that drivers should do, such as checking windshield wiper fluid levels, and how to change engine oil. Altogether the videos will last approximately 1 hour.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attention Maintenance Training
Description: The attention maintenance training is comprised of three modules. Each module is comprised of four scenarios, with each scenario corresponding to one activity. The entire training is expected to take approximately an hour to complete.
Study: NCT05885516

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: intrauterine insemination
Description: Giving washed sperm concentrate into uterine cavity via a soft catheter
Study: NCT04773561

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Corneal tomography, optical coherence tomography and optical coherence tomography angiography
Description: Ocular investigations were performed in one time during 30-36 weeks of gestational age. Due to avoidance of diurnal variation, all examinations were done between 10 am - 12 pm.
Study: NCT05885516

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: intrauterine insemination
Description: Giving washed sperm concentrate into uterine cavity via a soft catheter
Study: NCT05277194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: KeepCalm app
Description: The KeepCalm app is designed to help manage stress and prevent challenging behaviors in children with autism.
Study: NCT04693091

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Senti V1.0 Device
Description: This device class I, CE marked garment, with a similar form to a T-Shirt, embedded with ten sensor modules encased in silicone; the device comes with a charging stand in the form of a clothes hanger. Depending on the outcome of this feasibility study, the device may, in the future, form part of a class IIb medical device system, when accompanied by cloud-based software to listen to both current and historically recorded breath sounds for each Senti patient. The Senti Version One device will be labelled clearly to indicate the device version, on the inside of the garment, conforming to the MDR.~The garment itself will be made from textile composite, including cotton, elastase, micromodel, spandex, and polyester. All other components (including electronic and other plastic components) will be entirely encased in medical-grade silicone.
Study: NCT04972097

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Irreversible Electroporation
Description: IRE of the prostate is typically performed with the subject in the lithotomy position, with 2-6 monopolar probes placed through the perineum using a brachytherapy grid and ultrasound or CT guidance. IRE supplies the targeted tissue with high voltage (2-3 kV) direct current pulses lasting up to 100 microseconds through the electrode probes.
Study: NCT05535790

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Naturalistic LED light
Description: Naturalistic LED light (bright light therapy) which affects Melanopic Equivalent Daylight Illuminance.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard/traditional lighting
Description: Standard/tradtional lighting environment with fluorescent tubes
Study: NCT05455645

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: targeted intrinsic foot muscle exercises
Description: 4 targeted intrinsic foot muscle exercises
Study: NCT04773561

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Corneal tomography, optical coherence tomography and optical coherence tomography angiography
Description: Ocular investigations were performed in one time during 30-36 weeks of gestational age. Due to avoidance of diurnal variation, all examinations were done between 10 am - 12 pm.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Corneal tomography, optical coherence tomography and optical coherence tomography angiography
Description: Ocular investigations were performed in one time during 30-36 weeks of gestational age. Due to avoidance of diurnal variation, all examinations were done between 10 am - 12 pm.
Study: NCT06687226

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Reconstitutable food powder
Description: During the intervention week, participants will be asked take one dose of a reconstitutable food powder provided in a ziplock bag. This powder will be a mix of Gatorade Zero Powder (1 serving) and 1 serving of commercially available powders of either one or all of the following: camu camu, kelp or maqui. The powder mix in the bag will be added to water and drunk by the participant as soon as possible after having a bowel movement (baseline stool sample). Food powders are sourced from reputable companies and are safe for consumption (Gatorade is a wellrecognized brand and available in grocery stores nationally, Navitas Organics provides certified organic, third-party tested plant food powders with fairtrade certification).
Study: NCT06223373

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blood Flow Restriction
Description: In the BFR group, the tourniquet will be pressurized to 50% limb occlusion pressure (LOP), which is the pressure necessary for occluding 50% of arterial limb flow in the upper extremity.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham Blood Flow Restriction
Description: In the sham BFR group, the tourniquet will be pressurized to 0% occlusion pressure, while maintaining enough pressure to keep the tourniquet in place.
Study: NCT06008769

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 12 Week Manualized Cognitive-Behavioral Therapy Intervention
Description: The manualized intervention, Cognitive Behavioral Therapy for Opioid Use Disorder, was co-written and developed by the study PI, Dr. Lent (see Appendix). The manual consists of one module (Module 0) on assessment and 12 modules of CBT. This study will focus on delivery of Modules 1-12 that focus on several tenets of CBT, including skill development (cognitive restructuring, refusal skills, problem-solving, coping strategies), functional analysis (triggers, reinforcement) and utilizing the cognitive model.
Study: NCT06699537

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: probiotic product
Description: During the study, subjects take one sachet of Lactobacillus rhamnosus LRa05 daily. Evaluation is conducted by monitoring the subjects' nasal symptoms and gut microbiota before and after the intervention.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: During the study, subjects in the control group take one sachet of maltodextrin daily with 3.0g. Evaluation is conducted by monitoring the subjects' nasal symptoms and gut microbiota before and after the 8-week trial.
Study: NCT05750615

Intervention type: OTHER
Intervention: Uncertain what intervention will be co-created
Description: Uncertain what intervention will be co-created
Study: NCT06698757

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Sintilimab
Description: Subjects were enrolled and received Sintilimab at a dose of 200 mg, administered via intravenous infusion on the first day of each cycle, with each cycle lasting 3 weeks (Q3W)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: Subjects were enrolled and received Sintilimab at a dose of 200 mg, administered via intravenous infusion on the first day of each cycle, with each cycle lasting 3 weeks (Q3W)
Study: NCT06699485

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low carb diet
Description: Low-carbohydrate diet contains (\<26% carbohydrates) or less than 130 g/d
Study: NCT06479889

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guardians receiving counseling + lock
Description: Guardians of patients admitted to the Pediatric Hospital Medicine behavioral health team will be provided a brief lethal means educational session and offered up to 3 secure storage devices of their choosing (lock box and or cable locks)
Study: NCT05460910

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stability exercises with treadmill
Description: swiss ball use patient is lying in supine position with 15 repitations and 3 sets.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stability exercise without treadmill
Description: technique used to improve stability
Study: NCT05905549

Intervention type: PROCEDURE
Intervention: extended pancreatic transection during laparoscopic pancreaticoduodenectomy
Description: the pancreatic transection was performed at the pancreatic neck beyond the left side of the mesenterico-portal axis during laparoscopic pancreaticoduodenectomy
Study: NCT04536922

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Days -7 and -6: Cyclophosphamide 60 mg/kg/day x 2 days IV in 250 mL D5W infused simultaneously with mesna 15 mg/kg /day over 1 hour x 2 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Days -7 to -3: Fludarabine 25 mg /m2/day IVPB daily over 30 minutes for 5 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aldesleukin
Description: Aldesleukin 720,000 IU/kg IV (based on total body weight) over 15 minutes approximately every 8 hours beginning within 24 hours of cell infusion and continuing for up to 4 days (maximum 10 doses).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab (KEYTRUDA(R))
Description: Pembrolizumab 2 mg /kg IV over approximately 30 minutes on Days -2, 21, 42, and 63.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Individual Patient TCR-Transduced PBL
Description: Day 0: Cells will be infused at a dose not to exceed 1.5e11 in 400 mL intravenously on the Patient Care Unit over 20-30 minutes (2-4 days after the last dose of fludarabine).
Study: NCT04003480

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FRAME
Description: External support for vein grafts in peripheral bypass surgery
Study: NCT05258084

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sexual minority awareness training
Description: sexual minority awareness training is planned as 4 interviews (1 interview per week) for a total of 4 hours. Gender and sexuality-related terminologies and concepts will be discussed in the 1st meeting. Expression of sexual identity and gender transition processes will be examined in the 2nd meeting. In the 3rd meeting, the determining factors in the inadequate utilization of health services by LGBT individuals will be discussed. In the 4th meeting, what can be done to create a safe and health-friendly environment for LGBT individuals and healthcare professionals will be discussed.
Study: NCT06252896

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: INSTRUMENTAL-ASSISTED SOFT TISSUE MOBILIZATION TECHNIQUE
Description: After all evaluations were made, IASTM was applied to the individuals in the intervention group for five minutes each, for a total of 20 minutes, on the quadriceps and hamstring muscles of both extremities, respectively.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: NO INTERVENTION
Description: The control group waited for 30 minutes after the initial measurements and all measurements were repeated.