TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05916729

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Miconazole
Description: Protocol for active control groups includes use of Miconazole Oral gel for 14 days with frequency of four time per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: CandBerrol® lozenges
Description: Protocol for experimental groups includes use of Miconazole Oral gel and CandBerrol® lozenges for 14 days with frequency of four time per day

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: CandBerrol® lozenges
Description: Protocol for experimental groups includes use of Miconazole Oral gel and CandBerrol® lozenges for 14 days with frequency of four time per day

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: CandBerrol® lozenges
Description: Protocol for experimental groups includes use of Miconazole Oral gel and CandBerrol® lozenges for 14 days with frequency of four time per day
Study: NCT05301036

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Diadem prototype
Description: Diadem prototype device delivers personalized low-intensity transcranial focused ultrasound stimulation
Study: NCT06203977

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colchicine
Description: 0.3mg and 0.6mg tablets

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colchicine
Description: 0.3mg and 0.6mg tablets
Study: NCT05549375

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MyHand System Hand Rehabilitation
Description: 15 1-hour patient specific sessions using the MyHand System to help improve Hand function in the affected hand of stroke survivors
Study: NCT04969315

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TT-10
Description: TT-10 orally administered BID starting at 10 mg and will be increased to 200 mg (additional dose levels maybe explored, if appropriate based on emerging safety, PK or PD data).
Study: NCT05716243

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The nociception level index monitorization
Description: The nociception level index (NOL) is one of the nociception monitors and stands out from the others with its multi-parameter evaluation. It is generated from five different parameters (heart rate, heart rate variability, skin conductance level, photo-plethysmography waveform amplitude, number of skin conductance fluctuations, and their time derivatives).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: The nociception level index measurement;postoperative
Description: The nociception level index (NOL) will be used postoperatively
Study: NCT05501184

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Synchronous Exercise Program
Description: The exercise program consisted of exercises by recommended guidelines for nonspecific neck pain patients which includes various strengthening, stretching, and proprioceptive exercises with progression.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Asynchronous Exercise Program
Description: The exercise program consisted of exercises by recommended guidelines for nonspecific neck pain patients which includes various strengthening, stretching, and proprioceptive exercises with progression.
Study: NCT05977348

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Eating Curriculum
Description: The Healthy Eating (HE) curriculum is designed to provide children with skills needed to develop healthy eating habits. Each lesson builds upon the overall goal of creating a healthy restaurant. Children are taught to identify differences between GO and WHOA foods, recognize the five food groups, and learn to make healthy food choices.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Improving the Classroom Food and Mealtime Environment
Description: HBP+ Classrooms will receive additional sensory activities for each lesson (e.g., posters, food models, games) designed to improve the classroom food environment and provide repeated exposure to activities and messages about fruits and vegetables. Teachers in HBP+ classrooms will be provided with additional training on strategies shown to increase food acceptance in preschool children (e.g., modeling, encouraging children to try foods without coercion). In addition, HBP+ classrooms will include tasting charts that children will stamp to indicate their liking for each food each week.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent Education
Description: Parents in intervention classrooms will be given access to 8 web-based lessons on food parenting and responsive parenting. Topics include: establishing mealtime routines, shopping healthy on a budget; modeling of healthy eating behaviors; addressing picky eating in children; structuring low-stress mealtime environments; the division of responsibility in feeding, and portion control.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ECE Food Acceptance Training
Description: HBP+ early childhood educators (ECEs) will be asked to complete an online, self-paced course on increasing food acceptance in preschool children. Topics will include: repeated exposure to foods; modeling of healthy eating behaviors; addressing picky eating in children; structuring low-stress mealtime environments; and the division of responsibility in feeding.
Study: NCT05805410

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: robotic hippotherapy
Description: A custom designed cable-driven robotic system that mimics horseback movement during walking was used in this study.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Stretching of trunk and leg muscles, followed by sitting and standing balance training, and conventional treadmill walking.
Study: NCT06508736

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Storytelling
Description: It is aimed that adolescents gain behavioral change through stories.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Training
Description: Participants will be trained on cyberbullying in 4 sessions.
Study: NCT06546176

Intervention type: OTHER
Group type: OTHER
Intervention: End to end with Omega suture
Description: After the rectum was divided with a linear stapler, the circular stapler was placed allowing the anvil rod to penetrate the rectal stump near the linear stapler line. An omega suture including both ends of the linear stapler line was placed. The linear stapler line was approximated around the anvil rod of the circular stapler in an omega shape fashion as the omega suture was tied. This technique resulted in a complete resection of linear stapler line by the circular stapler.

Intervention type: OTHER
Group type: OTHER
Intervention: End to anterior rectal wall
Description: A burse string suture was applied over the anvil of the circular stapler at the transection point of the descending colon using prolene 2/0.~The circular stapler introduced though the anus and its rod directed toward the anterior rectal wall and colorectal anastomosis was performed.
Study: NCT06526624

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-20093
Description: Subjects in experimental arm will be given HS-20093 intravenously at a dose of 8.0 mg/kg every 3 weeks, until disease progression or until other criteria for treatment discontinuation are met.
Study: NCT05709925

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Instrument Assisted Soft Tissue Mobilization
Description: The Graston Technique which is the Instrument Assisted Soft Tissue Mobilization is the use of a firm instrument to break tissue adhesions and mobilize scar tissue thus improving pain, range of motion and disability.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: myofascial release
Description: myofascial release through stripping technique to the lumbar region.
Study: NCT05953116

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nutrition supplementation
Description: Blinded researchers will provide the randomly assigned supplement product to the trial participants for a period of 90 days. Used packaging will be collected at the end of every week from each trial participant to monitor compliance.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Nutrition supplementation
Description: Blinded researchers will provide the randomly assigned supplement product to the trial participants for a period of 90 days. Used packaging will be collected at the end of every week from each trial participant to monitor compliance.
Study: NCT06548425

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Smart Phone Based Cardiac Telerehabilitation
Description: Smart Phone Based Cardiac Telerehabilitation~Frequency:3 sessions per week for 8 weeks Intensity: 40-60 % THR and modified borg scale 9 (very light- 13 (somewhat hard) Time: Approx. 30 Min Type: Aerobic \& strength Exercises
Study: NCT05953116

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Trained researchers will facilitate resistance-based exercises two to three times a week in an enclosed venue (gym). Trial participants will be assessed at baseline for one repetition maximum (1RM) which will serve as a basis for load progression. A target of 3 sets and 6-15 repetitions with at least 30 seconds rest in between sets will be performed by the trial participants under supervision of a trained researcher.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Exercise
Description: Trained researchers will facilitate resistance-based exercises two to three times a week in an enclosed venue (gym). Trial participants will be assessed at baseline for one repetition maximum (1RM) which will serve as a basis for load progression. A target of 3 sets and 6-15 repetitions with at least 30 seconds rest in between sets will be performed by the trial participants under supervision of a trained researcher.
Study: NCT06548425

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Center based cardiac Rehabilitation
Description: Center based cardiac Rehabilitation~Frequency:3 sessions per week for 8 weeks Intensity: 40-60% THR and modified borg scale 9 (very light- 13 (somewhat hard)~Time: Approx. 30 Min Type: Aerobic \& strength Exercises
Study: NCT05847348

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-PSMA-11
Description: A single dose of 111 - 259 MBq administered intravenously over 3 -5 minutes
Study: NCT05997576

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TG103 22.5 mg
Description: Subcutaneous injections with calorie restrict diet and increased physical activity for 52 weeks. Doses gradually increased from 7.5 mg to 22.5 mg.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subcutaneous injections with calorie restrict diet and increased physical activity for 52 weeks.
Study: NCT06288971

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities
Description: - Self-adaption web-based software integrated with neuropsychomotor activities in small groups to strengthen EF. The training will take place bi-weekly, for 3 months, for approximately 60 minutes per meeting. For the intervention will be used the Bee-bot, a robot to be programmed to achieve objectives set in space, allows to stimulate navigation, visuospatial working memory and planning skills (the activities will be taken from those already used in our previous studies in children with typical development and BES (Di Lieto et al., 2020)).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tele-rehabilitation of EF and specific cognitive processes underlying academic skills
Description: - Tele-rehabilitation intervention on FE (RuntheRAN and MemoRAN). The training will be conducted at home, with periodic meetings with the clinician, for 3 months, for approximately 4/5 days a week for approximately 30/40 minutes per day. An adult (e.g. a family member) will support the child in the treatment and ensure that the exercises are carried out adequately at home. One of the following tele-rehabilitation software will be used: RuntheRAN (RidiNet, Coopertiva Sociale Anastasis), a software that aims to strengthen the prerequisites of reading by requiring the timed and progressively faster naming of colour matrices or black and white figures. MemoRAN (RidiNet, Cooperativa Sociale Anastasis), which involves rapid naming exercises of stimuli (figures and colors) presented in matrices, within tasks that require inhibition, cognitive flexibility and updating in working memory.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Game-based tools for the rehabilitation of EF and motor planning
Description: - MondoELLI intervention (Cooperativa Sociale Anastasis) integrated with neuropsychomotor activities. The game-based app involves activities in small groups to strengthen various components of EF (interference control, inhibition, working memory, flexibility). The activities are organized with increasing difficulty, according to the self-adaptive algorithm, and within a narrative context.
Study: NCT05330858

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ESK-001
Description: Oral tablet or liquid

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ESK-001
Description: Oral tablet or liquid

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ESK-001
Description: Oral tablet or liquid

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ESK-001
Description: Oral tablet or liquid

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rabeprazole
Description: Oral Tablet
Study: NCT05338892

Intervention type: OTHER
Intervention: Non-Interventional
Description: No study treatment will be administered on this study.
Study: NCT05271955

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: e-GOLIAH
Description: Usual care plus electronic tablet with games application e-GOLIAH (Gaming Open Library for Intervention in Autism at Home)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual care which combines speech therapy, psychomotor, educational or psychological care with a developmental and / or behavioral orientation and a school life support during schooling.
Study: NCT06002347

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STAC Parent Module for Middle School
Description: The STAC Parent Module is a 30-minute pre-recorded online presentation that includes normative feedback, didactic information, a review of the student STAC strategies and corresponding strategies parents can use to support students who act as defenders, and information about perceptions vs. facts about bullying.
Study: NCT06057792

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: negative pulsed pressure AeroFlow system
Description: For the application of pulsatile negative pressure, the AeroFlow® equipment will be used, carried out by one of the researchers participating in the project.The application will be carried out addressing the structure of interest (scar), following the protocol established by INDIBA to release adhesions between the different depth planes. The work will consist of an application of pulsed negative pressure using suction cups, which will work automatically at a frequency and intensity tolerable by the patient.~Treatment protocol in 2 phases Total application time 15min~1. Static cup: preparation: Prepare the tissue surrounding the scar. 5min~2. Dynamic Cup: work: Lock the tissue around the scar and the scar itself.10min Suction mode: continuous with continuous sliding of the cup The number of treatment sessions will consist of a total of 6 sessions, so there will be two sessions over 3 weeks.
Study: NCT05847348

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PET/CT or PET/MRI
Description: PET/CT or PET/MRI will be acquired no sooner than 50 minutes post injection and not later than 100 minutes post injection with 68Ga-PSMA-11
Study: NCT04433052

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: personalised prevention program (PPP)
Description: Study subjects in the PPP arm will be invited to return to the study site six times over a three-year period (at V2/start of the study, V3/mo2, V4/mo6, V5/mo12, V6/mo18 and V7/mo36) to receive lifestyle coaching and exercise prescriptions led by a delegated member of the site staff and supervised by the investigator. Information on drug treatment will also be given by the investigator. These activities will be assisted by digital tools specifically designed for this study, the CoroPrevention Tool Suite.
Study: NCT05086263

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pico G2 4k
Description: On this virtual reality headset, it will be loaded with an educational virtual reality mock MRI training titled Ready Teddy. This training explains the procedure to the viewer and addresses common questions that individuals often have regarding an MRI. Furthermore, using audio/visual cues, when the viewer moves their head too much in a MRI like setting they are reminded to stay still. Biofeedback training is aimed to mimic the experience of the MRI with real audio recordings of image acquisition, in order to adequately train the view to stay still in an MRI procedure.
Study: NCT06458647

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video Streaming with Virtual Reality
Description: In the study, patients in the intervention group will be watched videos of natural landscapes such as mountains, beaches and waterfalls with virtual reality goggles before the angiography procedure.
Study: NCT05667025

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative rehabilitation
Description: Joint range of motion, strengthening, balance-coordination and stretching exercises included in the conservative physiotherapy program 5 days a week for a total of 6 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative rehabilitation
Description: Joint range of motion, strengthening, balance-coordination and stretching exercises included in the conservative physiotherapy program 5 days a week for a total of 6 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cycling Functional Electrical Stimulation in addition to Conservative Rehabilitation
Description: In addition to conservative treatment, cycling FES to the affected lower extremity for 20 minutes, 3 days a week for 4 weeks. During the treatment, the patient will be seated on a chair and her feet will be fixed to the pedal with velcro tape, and the comfort during the treatment will be provided with calf supports.
Study: NCT05279911

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: low-level laser therapy (LLLT)
Description: low-level laser therapy (LLLT) with dental implants has been suggested to improve bone quality during osseointegration. Low-level laser (Gallium Aluminum Arsenide Diode \[Ga-Al-As\]) (wavelength: 808 nm, average power density: 50 mW, circular spot diameter:0.71 cm, spot area: 0.4cm2) in continuous mode was applied in six points in contact with peri-implant soft tissue (1.23 minutes in each point of application; dose per point 11 J) before and immediately after suturing. The application points were divided into two points in the labial region where the implant would be placed (apical and cervical); two points in the lingual region (apical and cervical); and two points in the occlusal direction. After suturing the laser protocol was repeated in the same points following the same protocol, resulting in a total dose of 66 J for each application moment (before and after implant placement).
Study: NCT05065255

Intervention type: DEVICE
Intervention: SpeediCath® catheters
Description: Patients using SC catheters will be followed up in order to understand the major criteria in the choice of the catheter by the patients.
Study: NCT04976829

Intervention type: DEVICE
Intervention: Antibiotic stewardship and healthcare-associated infections surveillance assisted by computer
Description: Implementation - in our tertiary care university hospital - of a computerized-decision support system (CDSS) facilitating antibiotic stewardship and of an electronic surveillance software (ESS) facilitating infection prevention and control activities
Study: NCT05474534

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neurofeedback (MUSE 2)
Description: During each at-home treatment session, mothers will place the MUSE 2 on their heads and connect it to the app on their personal device. Their brain activity is monitored by the MUSE 2 and is represented on the app through audio-based feedback (e.g., birds chirping, sounds of waves lapping on the beach) that mothers will listen to with earbuds as they direct their focus on maintaining a calm state of mind during the session; when a calm state is maintained, they are rewarded with calming sounds. The goal is to gain increased conscious control over their own brain activity. The audio feedback, primarily composed of nature-based sounds, is meant to guide their brain activity into a calm state. The session will begin, and the MUSE 2 will provide audio feedback in real time to guide their brainwave activity into an optimal frequency bandwidth range (e.g., as their brain activity reaches the target state, sounds of wind would subside to peaceful waves or other rewarding audio feedback).
Study: NCT05480449

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Humanized CD19-Directed Chimeric Antigen Receptor T-Cells (huCART19)
Description: The investigational agent in this protocol is humanized CART19 cells (huCART19). Autologous T cells will be engineered to express an extracellular single chain antibody (scFv) with specificity for CD19. This will be expected to redirect specificity of the transduced T cells for cells that express CD19, a molecule that is restricted in expression on the surface of the malignant cells and on normal B cells.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Humanized CD19-Directed Chimeric Antigen Receptor T-Cells (huCART19)
Description: The investigational agent in this protocol is humanized CART19 cells (huCART19). Autologous T cells will be engineered to express an extracellular single chain antibody (scFv) with specificity for CD19. This will be expected to redirect specificity of the transduced T cells for cells that express CD19, a molecule that is restricted in expression on the surface of the malignant cells and on normal B cells.
Study: NCT04825431

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAS-205, [14C]TAS-205
Description: single oral administration under fasted conditions on day 1
Study: NCT05292118

Intervention type: DEVICE
Intervention: Navitian
Description: Patients in whom treatment with (Navitian) has been attempted
Study: NCT05039658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI110 plus sintilimab
Description: Sintilimab is a NMPA approved high-affinity, ligand-blocking, humanized anti-programmed death-1 (PD-1) IgG4 antibody that blocks the binding of Programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2) to PD-1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI110
Description: BI110 is a high-affinity, ligand-blocking, humanized anti- Lymphocyte Activation Gene-3 (LAG-3) IgG4 antibody that blocks the binding of LAG-3 to MHCII.
Study: NCT04831099

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Testosterone gel
Description: The route of administration is transdermal.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The route of administration is transdermal