Study: NCT05713721

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: DEVICE
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS over the left primary motor cortex will be performed. To investigate sensorimotor integration, an electrical stimulus on the right index finger will precede the TMS pulse.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: Video-based clinical examination
Description: A standardized neurological examination will be performed and video taped. The videos will be rated by movement disorder specialists, wo are blinded for the symptom and mutation status of the participants.

Intervention type: OTHER
Intervention: 24 hours drug withdrawal of dopaminergic medication
Description: Examinations will be done under chronic dopaminergic treatment and after a 24 hours dopaminergic drug withdrawal.

Intervention type: OTHER
Intervention: 24 hours drug withdrawal of dopaminergic medication
Description: Examinations will be done under chronic dopaminergic treatment and after a 24 hours dopaminergic drug withdrawal.