TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05799937

Intervention type: PROCEDURE
Intervention: Non Surgical Root Canal Treatment
Description: After administration of LA and rubber dam isolation, access cavity will be prepared using carbide burs in high speed hand piece with copious irrigation. Working length will be determined using root ZX apex locator and will be verified radiographically. Canal preparation will be done with rotary instruments . 5ml of 5.25% NaOCl will be used as irrigant after each instrument. After instrumentation , the canals will be irrigated with 5.0 ml of 17% EDTA for 1minute followed by irrigation with 5.0 ml of 5.25% NaOCl. Canals will be dried with absorbent paper points, filled with calcium hydroxide paste and access cavity will be restored with IRM. Patients will be recalled after 1 week.At the next appointment, after paste removal, copious irrigation with 5.25% NaOCl will be done and canals will be dried with paper points. Canals will be obturated with Gutta-Percha and ZOE based sealer.

Intervention type: PROCEDURE
Intervention: Non Surgical Root Canal Treatment
Description: After administration of LA and rubber dam isolation, access cavity will be prepared using carbide burs in high speed hand piece with copious irrigation. Working length will be determined using root ZX apex locator and will be verified radiographically. Canal preparation will be done with rotary instruments . 5ml of 5.25% NaOCl will be used as irrigant after each instrument. After instrumentation , the canals will be irrigated with 5.0 ml of 17% EDTA for 1minute followed by irrigation with 5.0 ml of 5.25% NaOCl. Canals will be dried with absorbent paper points, filled with calcium hydroxide paste and access cavity will be restored with IRM. Patients will be recalled after 1 week.At the next appointment, after paste removal, copious irrigation with 5.25% NaOCl will be done and canals will be dried with paper points. Canals will be obturated with Gutta-Percha and ZOE based sealer.
Study: NCT05156463

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PAI Tool and Exercise Coaching
Description: Use of PAI tool and self-monitoring tools to increase physical activity and reduce sedentary behaviors. Participants will receive a personalized physical assessment and counseling from healthcare provider, exercise logs and a Garmin activity tracker to use between visits and 9 exercise coaching calls between clinical visits.
Study: NCT05790213

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apalutamide Oral Product
Description: Apalutamide 240 mg by mouth daily for a total of 6-months.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Androgen Deprivation Therapy (ADT)
Description: ADT therapy will consist of any generic luteinizing hormone-releasing hormone agonist which will provide either 6-months of treatment or two injections every 3-months. (e.g., one injection with a treatment period of 6 months or two injections, one at drug start and one 3-months later).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Focal Therapy
Description: Focal therapy to be completed within 8- to 12-weeks of the initiation of apalutamide but after the completion of the 8-week mpMRI to allow for it to be used in FT planning.
Study: NCT06215651

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab lenvatinib
Description: ±TACE/HAIC
Study: NCT05199805

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based pain management
Description: The structured program will include mindfulness exercises, meditation, a gentle body exercise series, and body awareness exercises, as well as information about pain, mindfulness-based pain management, and pain regulation methods suitable for everyday life. During the 8 weeks, treatment as usual is allowed.
Study: NCT05386251

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BPT/OST
Description: See Arm description.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Peer Support
Description: See Arm description
Study: NCT05059054

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strengthening exercise
Description: Strengthening exercise program Participants performed this protocol at home for 3 times per day. The participants progress their exercise based on the achievement of the previous level of each exercise protocol. The physical therapist recorded the level of each exercise for each participant during eight times of treatment. Total time for this section is approximately 30 minutes. Detail of the strengthening exercise is in the following.~1. Toe curl exercise (toe flexors strengthening)~2. Ankle evertor exercise (peroneal strengthening)~3. Ankle invertor exercise (tibialis posterior strengthening)~4. Heel raise exercise (high-load strength training)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Insole (CFO) group
Description: The CFO insole group The participants will receive the foot assessment before making the CFO for each participant. The 3-quarter-length CFO will be made from thermoplastic material (rigid foot orthoses) which consists of four layers i.e. two layers of 0.5-mm polyvinyl chloride (PVC) and one layer of 1.5-mm thick fiber to increase strength of foot orthoses in the bottom layers as well as one layer of 1.2-mm genuine leather in the upper layer to increase comfort.~The participants will be asked to use the CFO in daily life during weight-bearing activities.
Study: NCT06382285

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Continues peripheral block
Description: ropivacaine (Naropin) 0.2% according to a protocol 8-10 cc per hour up to 24 hours after surgery

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Continues peripheral block
Description: ropivacaine (Naropin) 0.2% according to a protocol 8-10 cc per hour up to 24 hours after surgery
Study: NCT05091866

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Therapeutic Progesterone
Description: Given SC
Study: NCT06386263

Intervention type: DRUG
Intervention: Trastuzumab deruxtecan
Description: This is a non-interventional, observational study. Patients who are enrolled by their clinician will receive T-DXd per routine clinical practice through the PSP.

Intervention type: DRUG
Intervention: Trastuzumab deruxtecan
Description: This is a non-interventional, observational study. Patients who are enrolled by their clinician will receive T-DXd per routine clinical practice through the PSP.
Study: NCT05250258

Intervention type: OTHER
Intervention: Telephone peer support by telephone
Description: Peer support by telephone from experienced father to new father with depressive symtoms.~4 times or more if requested during 4 months
Study: NCT06361667

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Arts
Description: Arts (music, cinema, dance).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Arts
Description: Arts (music, cinema, dance).
Study: NCT06576687

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical Rehabilitation
Description: Exercises include (1) single-limb hops to stabilization, (2) hop to stabilization and reach, (3) unanticipated hop to stabilization, (4) single-limb stance activities, and (5) continuous choice-reaction hopping.
Study: NCT00960921

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iron sucrose
Description: An intravenous infusion of 100 mg of iron is administered on days 0, 4, 8, 12, 16 and 20 of the study, giving a total of six iron infusions for each participant in the iron group over the course of the 28-day study period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: An intravenous infusion of 100 ml of normal (0.9 %) saline is administered on days 0, 4, 8, 12, 16 and 20 of the study, giving a total of six saline (placebo) infusions for each participant in the saline group over the course of the 28-day study period.
Study: NCT06220383

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hall technique
Description: Prepless crown technique

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional technique
Description: 1 or 1,5 mm preparation on mesial, distal and occlusal of the tooth
Study: NCT05613998

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GPR Group
Description: 6-week treatment using the GPR method. 1 weekly session (45 min) with frog on the ground and sitting postures + daily home self-postures (10 min)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercice Group
Description: 6-week nonspecific aerobic exercise treatment. Participants will take a daily walk (20 min)
Study: NCT05916859

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group 2 PDT (10 s)
Description: - Conventional endodontic treatment associated with PDT (10 s)
Study: NCT06347029

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Urine sampling
Description: Urine sampling

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Urine sampling
Description: Urine sampling

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Urine sampling
Description: Urine sampling

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Urine sampling
Description: Urine sampling

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: Blood sampling
Study: NCT05916859

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group 3 PDT 20 s
Description: Conventional endodontic treatment associated with PDAT (20 s)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Group 1. Placebo
Description: Conventional endodontic treatment
Study: NCT06471569

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low/Mod
Description: Aerobic exercise at 50% peak oxygen consumption expending approximately 1000 kilocalories per week equaling approximately 10 miles per week

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High/Mod
Description: Aerobic exercise at 50% peak oxygen consumption expending approximately 1600 kilocalories per week equaling approximately 16 miles per week

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High/Vig
Description: Aerobic exercise at 75% peak oxygen consumption expending approximately 1600 kilocalories per week equaling approximately 16 miles per week
Study: NCT05153200

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Upadacitinib
Description: 15 mg po daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adalimumab
Description: 40 mg sc every other week
Study: NCT06482684

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KTE-X19
Description: See description of treatment arms

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibrutinib
Description: See description of treatment arms
Study: NCT05714605

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: THRIVE Intervention
Description: The THRIVE Clinical Pathway is a standardized transitional care clinical pathway that supports Medicaid insured or Medicaid eligible individuals following hospitalization.
Study: NCT06413784

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Morning chronotype
Description: Sleep quality, gestational diabetes and pregnancy symptoms of morning chronotype individuals were examined.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intermediate chronotype
Description: Sleep quality, gestational diabetes and pregnancy symptoms of intermediate chronotype individuals were examined.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evening chronotype
Description: Sleep quality, gestational diabetes and pregnancy symptoms of evening chronotype individuals were examined.
Study: NCT06482684

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibrutinib
Description: See description of treatment arms
Study: NCT05779306

Intervention type: DEVICE
Intervention: IOL Master 700
Description: Biometry using the IOL Master 700

Intervention type: DEVICE
Intervention: IOL Master 700
Description: Biometry using the IOL Master 700

Intervention type: DEVICE
Intervention: Casia-2
Description: Anterior segment-OCT to evaluate lens tilt

Intervention type: DEVICE
Intervention: Casia-2
Description: Anterior segment-OCT to evaluate lens tilt

Intervention type: DEVICE
Intervention: MS-39
Description: Corneal Topography using the MS-39

Intervention type: DEVICE
Intervention: MS-39
Description: Corneal Topography using the MS-39

Intervention type: DEVICE
Intervention: OSIRIS
Description: Abberometry using the OSIRIS-Abberometer

Intervention type: DEVICE
Intervention: OSIRIS
Description: Abberometry using the OSIRIS-Abberometer

Intervention type: DEVICE
Intervention: Autorefractor
Description: Evaluation of Refraction using an Autorefractor

Intervention type: DEVICE
Intervention: Autorefractor
Description: Evaluation of Refraction using an Autorefractor

Intervention type: DIAGNOSTIC_TEST
Intervention: Subjective Refraction
Description: Refraction performed by experienced staff

Intervention type: DIAGNOSTIC_TEST
Intervention: Subjective Refraction
Description: Refraction performed by experienced staff
Study: NCT06202183

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Program
Description: A 12 week, home-based, virtually supervised, aerobic and resistance exercise training program comprised of 36 sessions. Participants will be provided with a home stationary bike, resistance bands, and Fitbit. Virtually supervised sessions will be accessible via Zoom platform. For participants who do not have a device, a Wi-Fi-enabled tablet will also be provided.
Study: NCT05003388

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AlloRx
Description: cultured allogeneic adult umbilical cord derived mesenchymal stem cells
Study: NCT05529745

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurorehabilitation cerebellar cognitive disorder
Description: Influence of neurorehabilitation treatment lines of physiotherapy and exercise therapy including scheduled occupational therapy to adapt and improve cognitive-affective disorders in cerebellar lesions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neurorehabilitation cerebellar cognitive disorder
Description: Influence of neurorehabilitation treatment lines of physiotherapy and exercise therapy including scheduled occupational therapy to adapt and improve cognitive-affective disorders in cerebellar lesions.
Study: NCT05453747

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: After evaluating the age groups and physical characteristics of the athletes under the titles of Warm-Up, Core/Balance/Reactive, Speed/Agility/Quickness, Resistance and Cool-Down, the exercise programs that differ for the athlete under these exercise types are listed with the NASM program and shared with the athletes. During the 8-week period between the 2 evaluations, it was applied 2 days a week on the team's fitness days.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise 2
Description: After evaluating the age groups and physical characteristics of the athletes under the titles of Warm-Up, Core/Balance/Reactive, Speed/Agility/Quickness, Resistance and Cool-Down, the exercise programs that differ for the athlete under these exercise types are listed with the NASM program and shared with the athletes. During the 8-week period between the 2 evaluations, it was applied 2 days a week on the team's fitness days.
Study: NCT06172608

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: psychoeducational intervention
Description: . Intervention group (I) will receive psychosocial education which will be consist of two parts. 1) Face to Face 2) Community based intervention.~1. Face to face: This face to face session will be consisting of 30-minute session soon after inclusion into the study. A leaflet consisting of all information will be provided to all the patents taking part in the study.~2. Community Based Intervention: In community based interventions prerecorded videos about all the topics covered in face to face session will be made available to parents via a secure online platform. Parents can easily browse it easily when they need it. These videos will be recorded in local language (Urdu), which is easy to understand for almost all the people.
Study: NCT04931394

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adjuvant chemotherapy guided by organoid drug sensitivity test
Description: Adjuvant chemotherapy guided by organoid will be given to pancreatic cancer patients.
Study: NCT06167551

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mother lullaby group
Description: mother's lullaby: the mother will be made to sing her own lullaby 5 minutes before the heel prick.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: white noise group
Description: white noise: 5 minutes before taking heel prick blood, white noise will be started to be played on an MP3 player with white noise. The MP3 player will be placed in the crib where the baby lies, at the baby's bedside, at least 20 cm away from the baby's head. After the MP3 player is turned on, the sound level will be measured at the baby's ear level with a decibel meter and adjusted so that it does not exceed 70 decibels.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: classical music group
Description: classical music: 5 minutes before heel prick, classical music will be started to be played from the MP3 player with white noise. The MP3 will be placed inside the crib where the baby lies, at the baby's bedside, at least 20 cm away from the baby's head. After the MP3 player is turned on, the sound level will be measured at the baby's ear level with a decibel meter and adjusted so that it does not exceed 70 decibels.

Intervention type: OTHER
Group type: OTHER
Intervention: Contol Group
Description: No intervation
Study: NCT04898712

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic Acid 500 MG
Description: Tranexamic Acid 500mg oral tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo will consist of an identical capsule to over-encapsulated tranexamic acid oral tablet entirely filled with microcrystalline cellulose, and sealed.
Study: NCT04485130

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disulfiram
Description: This study will provide disulfiram. Participants in Cohort 1 receiving disulfiram will take 2 capsules of disulfiram (each capsule contains 500 mg DSF plus 27.75 mg microcrystalline cellulose powder) per day for a total of 5 consecutive days. Participants in Cohort 2 receiving placebo will take 4 capsules of disulfiram (each capsule contains 500 mg DSF plus 27.75 mg microcrystalline cellulose powder) per day for a total of 5 consecutive days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: This study will provide placebo. Participants in Cohort 1 receiving placebo will take 2 capsules of placebo (each capsule contains only microcrystalline cellulose powder) per day for a total of 5 consecutive days. Participants in Cohort 2 receiving placebo will take 4 capsules of placebo (each capsule contains only microcrystalline cellulose powder) per day for a total of 5 consecutive days
Study: NCT05784805

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PLIFU
Description: Participants will be treated with up to 2 sessions of PLIFU (on the same day), while monitored with surface EEG and will be observed for the remainder of the hospital stay as deemed by the primary care team. The system non-invasively delivers ultrasound sonications intracranially that selectively target specific areas of the brain.
Study: NCT04888247

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CLARITY
Description: Trans-septal mitral valve replacement
Study: NCT05889923

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: With EDU
Description: using the EDU to perform the procedure
Study: NCT06205797

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HU-045
Description: HU-045 is a medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults for a short period of time (temporary). It should be reconstituted with sterile, preservative-free 0.9% saline before use.~White powder~Other Names:~IncobotulinumtoxinA

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Xeomin®
Description: Xeomin® is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults for a short period of time (temporary). It should be reconstituted with sterile, preservative-free 0.9% saline before use.~Other Names:~IncobotulinumtoxinA
Study: NCT05336201

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)
Description: Manualized cognitive remediation intervention that includes 1) skills-based remediation (metacognitive training), 2) parent training, and 3) cognitive behavioral approaches. Intervention targets self-management and goal-setting skill building to promote independence in activities necessary for transition of care.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)
Description: Manualized cognitive remediation intervention that includes 1) skills-based remediation (metacognitive training), 2) parent training, and 3) cognitive behavioral approaches. Intervention targets self-management and goal-setting skill building to promote independence in activities necessary for transition of care.
Study: NCT05520840

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: blood sampling for screening of biomarkers
Description: Patient aged 50 years or older referred for screening colonoscopy after a positive fecal immunochemical test or for endoscopic resection of a previously identified suspicious colorectal lesion will have a blood sampling for biomarkers detection
Study: NCT04662463

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Bias Modification for Interpretation (CBM-I)
Description: Patients will receive CBM-I training by reading and imaging themselves in a series of emotionally ambiguous scenarios. Each scenario ends with an incomplete final word. Patients need to complete the final word to resolve the scenario in a positive direction.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive placebo task which uses neutral rather than emotional material.
Study: NCT06004856

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orelabrutinib
Description: Orelabrutinib once daily (QD)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo once daily (QD)