TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04713241

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electro-acupuncture
Description: 20-30 minute acupuncture treatment in sessions from start of study (within 48 hours of diagnosis) to return of bowel functions~A practitioner stimulates certain points on the body by placing thin needles in the skin. Electrical stimulation is then added to some of the needles. This involves placing wires on the needles, which are connected to a machine that delivers a weak electrical current through the wires. The strength of the electrical current will be changed slowly until it is at a comfortable level.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Bowel rest
Description: Bowel rest with NPO status and placement of nasogastric tube (NGT) if clinically indicated

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care Bowel rest
Description: Bowel rest with NPO status and placement of nasogastric tube (NGT) if clinically indicated
Study: NCT04313062

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: An educational intervention based on the PM ACTIVAS' model and a  Falling Prevention Kit , both in a home visit by the trainees. Also, a telephone follow-up and a last house call 12 months after recruiting to assess the changes implemented by the person and their family, to conduct the final survey and to ask for the  Falls and Events Calendar  .
Study: NCT05220072

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbon-14 BIA 28-6156
Description: Carbon-14 BIA 28-6156 60 mg, containing NMT 3.7 MBq Carbon-14
Study: NCT05552989

Intervention type: OTHER
Intervention: this is a non-interventional study
Description: this is a non-interventional study
Study: NCT05546632

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sampling
Description: Patients will have one blood sampling using one EDTA tube and one Cyto-Chex BCT tube, one after the other
Study: NCT05477667

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: real time pcr
Description: Detection of expressin level of MiRNA-124 and let-7a using real time pcr

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: real time pcr
Description: Detection of expressin level of MiRNA-124 and let-7a using real time pcr

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: real time pcr
Description: Detection of expressin level of MiRNA-124 and let-7a using real time pcr
Study: NCT05807620

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gentle Cleansing Lotion
Description: Facial cleansing lotion to be used by study participants (morning and evening, 2x daily).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facial Moisturizer
Description: Anti-aging facial moisturizer to be used by study participants after anti-aging daily serum before sunscreen (morning and evening, 2x daily).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sunscreen SPF 30
Description: Neutrogena Ultra Sheer Dry Touch SPF 30. Sunscreen to be applied after application of the facial moisturizer in the morning. Participants were asked to reapply every 2 hours.~Per FDA this intervention is an over the counter
Study: NCT04496583

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fluid depletion strategy
Description: The fluid depletion strategy will be individualized depending on the response to the standardized furosemide test (one-time dose of 1.0 or 1.5 mg/kg depending on prior furosemide-exposure) with a urinary output (UO) cutoff of 200 ml at 2 hours. The desired depletion endpoint will be targeted by using diuretics (40 mg q6h iv initially, adjusting dose by UO) or ultrafiltration (UF) if UO \<200 ml/2h

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fluid depletion strategy
Description: The fluid depletion strategy will be individualized depending on the response to the standardized furosemide test (one-time dose of 1.0 or 1.5 mg/kg depending on prior furosemide-exposure) with a urinary output (UO) cutoff of 200 ml at 2 hours. The desired depletion endpoint will be targeted by using diuretics (40 mg q6h iv initially, adjusting dose by UO) or ultrafiltration (UF) if UO \<200 ml/2h
Study: NCT05303311

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: intrathecal injection of bupivacaine alone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pethidine plus Dexamethasone
Description: Intrathecal injection of pethidine plus dexamethasone
Study: NCT05136014

Intervention type: OTHER
Intervention: Collection of surgical waste
Description: collection of a fragment of healthy and tumorous lung tissue taken as part of the operating theatre procedure and normally destined to be destroyed
Study: NCT05000255

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention 1: According to DGP
Description: The first intervention is designed according to a current recommendation of the Deutsche Pneumologen Gesellschaft e.V. Its approach is resource-oriented, psychoeducational and is expected to have a positive effect on the symptomatology of depression and anxiety in the short and medium term. An additional focus was added to the intervention: planning more physical activity in daily life after discharge. The DPG intervention focuses more on the current state and aims to activate patients' resources in the short and long term. To ensure randomization of study participants, interventions will alternate weekly.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Intervention 2: According to Cacioppo E.A.S.E.
Description: The second intervention, E. A. S. E. according to Cacioppo and Patrick (2008), addresses the social action radius of patients (here assuming that loneliness is a predictor of depression). This intervention is about planning social activities against loneliness. Cacioppo's intervention aims to encourage more social activity in the long term.
Study: NCT04793737

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Precision Radiation (SBRT)
Description: Precision radiation of melanoma metastases
Study: NCT03931252

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Boost VHC
Description: 8 ounce can liquid meal, calories 530kcal, Carbohydrate 46g, Protein 22g, Fat 30g

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ensure High Protein
Description: 8 ounce can liquid meal, calories 160kcal, Carbohydrate 13g, Protein 16g, Fat 2g
Study: NCT05254704

Intervention type: OTHER
Intervention: TEX-Q-F before scheduled surgery
Description: The TEX-Q-F questionnaire (French version of the breif version of the TEX-Q) contains 15 questions to assess the patient's overall expectations concerning the surgery.~The first 11 questions concern the patient's expectations regarding the postoperative period: pain and functional recovery. The last 4 questions focus on the patient's hopes for the outcome of the surgery. Each item is scored from 0 to 10, according to the intensity of the level of expectation.

Intervention type: OTHER
Intervention: TEX-Q-F before scheduled surgery
Description: The TEX-Q-F questionnaire (French version of the breif version of the TEX-Q) contains 15 questions to assess the patient's overall expectations concerning the surgery.~The first 11 questions concern the patient's expectations regarding the postoperative period: pain and functional recovery. The last 4 questions focus on the patient's hopes for the outcome of the surgery. Each item is scored from 0 to 10, according to the intensity of the level of expectation.
Study: NCT05701501

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin B5 Tablets
Description: The experimental group was given Vitamin tablets (5mg/tablet) based on the standard IBD treatment.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: The control group was given placebo tablets of the same type based on the standard IBD treatment.
Study: NCT05172908

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: 5 mg dexamethasone in a 50 ml syringe containing normal saline will be infused within 15 minutes.~The syringe will be prepared by a nurse outside the research team and the Study participants, care providers, and data collectors will be blinded to the allocation throughout the study.~Global Quality of Recovery- 15 score and standard pain follow-up scores will be noted.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Saline
Description: A 50 ml syringe containing normal saline will be infused within 15 minutes. The syringe will be prepared by a nurse outside the research team and the study participants, care providers, and data collectors will be blinded to the allocation throughout the study.~Global Quality of Recovery- 15 score and standard pain follow-up scores will be noted.
Study: NCT04256083

Intervention type: BIOLOGICAL
Intervention: Biological analysis
Description: Two blood samples of 4 ml each (total: 8 ml) for IGFBP1 assay and metabolic phenotyping and proteomic analysis.

Intervention type: BIOLOGICAL
Intervention: Biological analysis
Description: Two blood samples of 4 ml each (total: 8 ml) for IGFBP1 assay and metabolic phenotyping and proteomic analysis.

Intervention type: BIOLOGICAL
Intervention: Biological analysis
Description: Two blood samples of 4 ml each (total: 8 ml) for IGFBP1 assay and metabolic phenotyping and proteomic analysis.
Study: NCT06394141

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Real-time triggers
Description: The first intervention group (n= 30 professional drivers) will receive real-time triggers related to acute stress and sleepiness/fatigue. The real-time feedback involves giving relevant triggers when exceeding some critical stress values or detecting events of \&#39;energy-takers\&#39; based on accurate measurements of mental energy in a fully automated way. The selected triggers will be based on the co-creation workshops with drivers (e.g., auditive, visual) in order to select the most efficient (type or combination of) trigger(s) for the real-time feedback. The warning messages will be tailored to the preferences of the driver (e.g., personalized comfort- and safety-related settings) and aim to generate a warning message/signal meant to alert drivers and prevent they might end up with high stress levels

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized tailored feedback
Description: The second intervention group (n= 30 professional drivers) will receive personalized tailored feedback to reduce chronic stress and sleepiness/fatigue. The advice involves personalized (semi-)automatic feedback to drivers about a reduced stress level via the mobile app with automatic reports, as well as post-intervention during the next work break or at the end of the workday, based on the preferences of the driver. The (semi-)automatic feedback is based on the theory of Stages of Change, by which a driver will only receive relevant feedback based on their attitude and willingness during daily life.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Real-time triggers + Personalized tailored feedback
Description: The third intervention group (n= 30 professional drivers) will receive both real-time feedback related to acute stress and sleepiness/fatigue, as well as personalized tailored feedback related to chronic stress and sleepiness/fatigue, similar as in the first and second intervention groups.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: App-supported exercise therapy
Description: The fourth intervention group (n= 30 professional drivers) will receive app-supported exercise therapy. The intervention will be based on principles of high-intensity training exercises that focus on the improvement of cardiorespiratory exercise capacity, as well as on the reduction of stress levels during work. Participants will receive instructions via the app to do some short, vigorous exercises adapted to their work environment at regular intervals, e.g., bending-and-stretching exercises with a weight in their hands, walking up and down the stairs of their vehicle for a few minutes, etc.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional intervention
Description: The active control group (n= 20 professional drivers) will get a conventional intervention to reduce stress, e.g., mindfulness.
Study: NCT06154213

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Building Habits Together
Description: Private, hidden Facebook group Building Habits Together includes 24 weeks on content based on the Diabetes Prevention Program and the Habit app.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Getting Healthy Together
Description: Private, hidden Facebook group Getting Healthy Together includes 24 weeks on content based on the Diabetes Prevention Program and the MyFitnessPal app.
Study: NCT04615377

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kaia hip and knee pain application
Description: The Kaia Knee and Hip pain app software, when loaded onto a smartphone, recommends to the participant specific exercises for the lower extremity. Using the camera on a smartphone, the software then tracks the participant's movements as the participant performs the exercises, analyzes those movements using machine learning, and provides audio-visual feedback to the participant. The exercise therapy is augmented by educational content and cognitive behavioral therapy to provide a multidisciplinary approach to self-management of osteoarthritis. Behavioral Health Coaches ensure participant motivation throughout the program based on a predefined curriculum.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: Participants allocated to the control arm will be advised to continue receiving treatment as usual ( standard care) without restrictions, except participation in other investigational trials, and will likewise be followed up for 90 days. Apart from that, they are encouraged to seek care, as they would do normally.
Study: NCT05045495

Intervention type: DIAGNOSTIC_TEST
Intervention: Sucrose Hydrogen Methane Breath Test
Description: Subjects will collect 2 buccal swabs for the sucrase genetic test and then subjects will simultaneously conduct the sucrose challenge test, sucrose hydrogen methane breath test, and the 13C-sucrose following ingestion of 50-grams of sucrose (table sugar) mixed with 8 ounce of water.

Intervention type: DIAGNOSTIC_TEST
Intervention: Sucrose Hydrogen Methane Breath Test
Description: Subjects will collect 2 buccal swabs for the sucrase genetic test and then subjects will simultaneously conduct the sucrose challenge test, sucrose hydrogen methane breath test, and the 13C-sucrose following ingestion of 50-grams of sucrose (table sugar) mixed with 8 ounce of water.
Study: NCT05486806

Intervention type: DRUG
Intervention: 18F-PBR06
Description: TSPO-PET (translocatior protein, positron emission tomography) scan

Intervention type: RADIATION
Intervention: 18F-PBR06
Description: TSPO-PET (translocatior protein, positron emission tomography) scan
Study: NCT05422898

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gist messages on COVID-19 vaccination
Description: Participants will receive gist-based messages on COVID-19 vaccines and have their concerns addressed by a group moderator

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: COVID-19 vaccine information
Description: Participants will receive a link to the Facebook COVID-19 Information Center via a private Facebook Group
Study: NCT05700019

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pinkwashed Advertisements
Description: Real advertisements from alcoholic beverage companies' social media accounts that contain messaging or other features that associate the alcohol company with breast cancer awareness or research.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control - Standard Advertisements
Description: Real advertisements from the same alcoholic beverage companies' social media accounts that do not contain messaging or other features associated with breast cancer awareness or research.
Study: NCT05654532

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AC699
Description: Participants will receive AC699 orally daily in 28-day cycles.
Study: NCT06039111

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ICG alone
Description: SLNs will be detected with ICG alone, labelled as such, and subsequent to that tested with Gamma probe for accuracy
Study: NCT05002296

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: upper cervical manipulation
Description: rotatory upper cervical manipulation to both sides. The treatment program was conducted for twelve sessions (three sessions per week). Assessment procedures were performed before and after treatment through visual analogue scale (VAS)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: upper cervical manipulation
Description: rotatory upper cervical manipulation to both sides. The treatment program was conducted for twelve sessions (three sessions per week). Assessment procedures were performed before and after treatment through visual analogue scale (VAS)
Study: NCT04230031

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Experimental
Study: NCT00823693

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bimosiamose Cream

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Cream
Study: NCT05127863

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: social communication intervention (pragmatic)
Description: 10 sessions of group intervention in order to improve pragmatic/social communication. one session of one hour per week. Activities will included role play, conversations, etc.
Study: NCT05228951

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib maleate, dalpiciclib, Trastuzumab, letrozole
Description: After providing written informed consent, the participants will undergo combined treatment of pyrotinib maleate, CDK4/6 inhibitor dalpiciclib, trastuzumab and letrozole. The effectiveness of the combined treatment will be evaluated by MRI every two treatment cycles. If the disease progresses, the participant will withdraw from the trial. If the combined treatment has identified effectiveness, the participant will undergo surgical treatment within 4 weeks (over 2 weeks) after termination of the neoadjuvant treatment. The patients will be followed up for 5 years.
Study: NCT05089825

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Receive routine instructions
Description: Study subjects randomized to this arm will receive a mailed myLab Box kit with instructions on HPV self-collection and postage to be shipped directly to the commercial lab. It should take less than 5 minutes to collect the sample.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Telehealth-based instructional visit and receive routine instructions
Description: Study subjects randomized to this arm will similarly receive a mailed myLab Box kit and also undergo a brief 5-10 telehealth instructional visit via video conference.
Study: NCT05820191

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amyvid, Intravenous Solution
Description: Amyvid 370MBq (10mCi) absorbed dose 7mSv of will be introduced intravenously and 30-50 minutes after the PET images will be acquired.
Study: NCT05858723

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ROAT
Description: Repeated Open Application Test

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ROAT
Description: Repeated Open Application Test
Study: NCT05036733

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Participants will receive 8 doses of Dupilumab. The initial loading dose (visit 1) of 600 milligrams (two 300 milligram injections) will be given subcutaneously (SQ). Then the participants will receive 300 milligrams SQ every other week (q 2 weeks) either at a study visit or self-administered at home between visits.~Additionally, participants will complete questionnaires, have specimens collected, as well as perform breathing procedures at various timepoints.
Study: NCT04761328

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive behavioral therapy
Description: Cognitive-behavioral therapy involves changing these erroneous cognitions and beliefs through cognitive restructuring, modification of behavior, and development of alternative coping skills.
Study: NCT04777175

Intervention type: DRUG
Intervention: immunity therapy
Description: The patient receives immunotherapy

Intervention type: DRUG
Intervention: immunity therapy
Description: The patient receives immunotherapy

Intervention type: DRUG
Intervention: immunity therapy
Description: The patient receives immunotherapy

Intervention type: DRUG
Intervention: immunity therapy
Description: The patient receives immunotherapy

Intervention type: DRUG
Intervention: immunity therapy
Description: The patient receives immunotherapy

Intervention type: DRUG
Intervention: immunity therapy
Description: The patient receives immunotherapy
Study: NCT06591078

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electropuncture
Description: The needle was retained for 30 minutes. During the retention period, the needle was lifted and twisted for 3 times with even small amplitude every 10 minutes, and the complement method was performed for 3 times. No manipulation before the needle, cotton ball press directly out of the needle.~④ Frequency, course and time: Start at the same time as immunotherapy, and complete 1-2 times of electroacupuncture treatment per week; Electroacupuncture was performed 4 times per 28 days. The number of electroacupuncture treatment cycles and the number of immunotherapy courses should be consistent.
Study: NCT06601764

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Circuit Training
Description: 1. Warm-up, balance~2. Aerobic, balance~3. Muscle strength Upper Limbs~4. Muscle strength Lower Limbs~5. Stretching both Upper Limb and Lower Limb

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Progressive Resistance
Description: 1. Muscle habituation exercises~2. Hypertrophic phase 1 exercises~3. Hypertrophic phase 2 exercises
Study: NCT06472232

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chloroprocaine
Description: Selection of low concentration of chloroprocaine as local anesthetic for labor analgesia

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Chloroprocaine
Description: Selection of low concentration of chloroprocaine as local anesthetic for labor analgesia
Study: NCT05985252

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Virtual ileostomy
Description: Laparoscopic or robotic surgery with virtual ileostomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Diverting ileostomy
Description: Laparoscopic or robotic surgery with diverting ileostomy
Study: NCT06398756

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional rehabilitation
Description: 17 patients with cerebral palsy meeting the criteria will undergo conventional rehabilitation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: aquatic therapy
Description: 17 patients with cerebral palsy meeting the criteria will undergo convertional rehabilitation and aquatic therapy