TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05797103

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands
Description: Electrolyzed water spray group will use the novel electrolyzed water spray to flush the hands that daub E. coli and attenuated human influenza virus H1N1 for 6 seconds per hand, and then use 4 seconds to collect a sample of the water flowing from the sprayed hand and apply it to the plate. Untreated tap water group will use the untreated tap water spray to flush the hands that daub E. coli and attenuated human influenza virus H1N1 for 6 seconds per hand, and then use 4 seconds to collect a sample of the water flowing from the sprayed hand and apply it to the plate.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands
Description: Electrolyzed water spray group will use the novel electrolyzed water spray to flush the hands that daub E. coli and attenuated human influenza virus H1N1 for 6 seconds per hand, and then use 4 seconds to collect a sample of the water flowing from the sprayed hand and apply it to the plate. Untreated tap water group will use the untreated tap water spray to flush the hands that daub E. coli and attenuated human influenza virus H1N1 for 6 seconds per hand, and then use 4 seconds to collect a sample of the water flowing from the sprayed hand and apply it to the plate.
Study: NCT06169514

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05001724

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: KN046
Description: KN046 is 5 milligram per kilogram, every 3 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Lenvatinib is RP3D milligram per day, every day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Docetaxel
Description: Docetaxel is 75 milligram per Square meter, every 3 weeks.
Study: NCT05095805

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: additional weight-bearing exercise
Description: Nintendo Wii Balance Board, real-time visual feedback, weight-bearing assessment by center of pressure

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: standard weight-bearing exercise
Description: conventional training for fitting of initial prosthesis
Study: NCT05796856

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: repeated low level light device (Eyerising [Suzhou Xuanjia Optoelectronics Technology)
Description: crossover device (repeated low level light device with wavelength of 810/650 nm- alternate to first group) Cross over arms after one month of use and one month of washout period.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: repeated low level light device (Eyerising [Suzhou Xuanjia Optoelectronics Technology)
Description: crossover device (repeated low level light device with wavelength of 810/650 nm- alternate to first group) Cross over arms after one month of use and one month of washout period.
Study: NCT06384586

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo shot
Description: 60ml shot served in an amber bottle and consumed after 40 minutes of baseline assessments

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo shot
Description: 60ml shot served in an amber bottle and consumed after 40 minutes of baseline assessments

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Functional energy shot
Description: 60ml shot served in an amber bottle and consumed after 40 minutes of baseline assessments

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Functional energy shot
Description: 60ml shot served in an amber bottle and consumed after 40 minutes of baseline assessments
Study: NCT05326022

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microcurrent therapy
Description: Microcurrent therapy

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Level Laser Therapy
Description: Laser therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical therapy
Description: Medical therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical therapy
Description: Medical therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical therapy
Description: Medical therapy
Study: NCT05662553

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ENB guided MWA combined with VATS
Description: ENB guide MWA combine ENB, microwave ablation and 3D reconstruction technology, and guide the probe in the airway to the target lesion for ablation therapy, which is safe and effective. For patients with synchronous bilateral multiple primary pulmonary nodules, ENB guide MWA combined with VATS treatment can not only avoid the risk of bilateral surgery, but also complete the one-stop treatment, which is a new treatment mode.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: sequential surgery
Description: Bilateral surgery is a traditional treatment, but it will lead to increased intraoperative risk and postoperative complication rate, and more likely to lead to postoperative complications such as decreased quality of life and cardiopulmonary dysfunction.
Study: NCT05492071

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Local Vibration Application Following Flow Mediated Dilation
Description: Flow mediated dilatation will be induced via 5 min cuff inflation below left elbow at suprasystolic pressures (50mmHg above preapplication systolic pressure). Vibration is applied with a commercially available vibration plate to forearm at 20 hz and 3 mm of vertical amplitude for 5 minutes, 30 minutes after termination of FMD.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Flow mediated dilation
Description: Flow mediated dilatation will be induced via 5 min cuff inflation below left elbow at suprasystolic pressures (50mmHg above preapplication systolic pressure).
Study: NCT04884659

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time restricted feeding arm
Description: 80% of calories consumed before 2PM, remaining 20% consumed by 4PM. Fasting for 14-16 hours

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time restricted feeding arm
Description: 80% of calories consumed before 2PM, remaining 20% consumed by 4PM. Fasting for 14-16 hours

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: usual feeding pattern arm
Description: All meals consumed ad lib with 50% of calories consumed after 4PM

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: usual feeding pattern arm
Description: All meals consumed ad lib with 50% of calories consumed after 4PM
Study: NCT04959058

Intervention type: DEVICE
Group type: OTHER
Intervention: Volunteer
Description: An ultrasound machine will be used to calculate the elastographic value of the brachial plexus in three different positions.
Study: NCT04593511

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY03009 F1
Description: a single dose of LY03009 F1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY03009 F2
Description: a single dose of LY03009 F2

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY03009 F3
Description: a single dose of LY03009 F3

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY03009 F4
Description: a single dose of LY03009 F4
Study: NCT05043025

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Identification of the cricothyroid membrane
Description: The cricothyroid membrane is identified using a laryngeal handshake technique in different patient positions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Identification of the cricothyroid membrane
Description: The cricothyroid membrane is identified using a laryngeal handshake technique in different patient positions.
Study: NCT06419842

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hypnosis
Description: the patient benefits from a dedicated nurse consultation. During this consultation, the nurse will explain the highlights of the hospitalization, the procedure and anticipate the hypnosis technique to be used. The technique chosen during the consultation will be applied during the test. The nurse is positioned at the head of the patient and with physical contact.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: comfort
Description: the patient benefits from a nurse consultation. Non-medicinal techniques are not offered. During the infusion test, the nurse will be positioned at the patient's head allowing proximity but without oral or physical intervention.
Study: NCT06577662

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: individual and family self-management (IFSM) fall prevention program
Description: The IFSM program lasts for ten weeks, two weeks in the hospital, and follow up at eight weeks after patients are discharged to home. It includes 11 sessions, including ten sessions developed in the inpatient department within two weeks and one online booster session developed in the first month (week 4) after discharge in home. There is also one session just for caregivers, and two phone-visit will be provided for follow up after patients discharged from the hospital except the training.~Session 1 : PRST combined with GRI (one) Session 2 : Environment safety Session 3 : Assistant technology Session 4 : PRST combined with GRI (two) Session 5 : Medication review Session 6 : Safety in daily activities Session 7 : How to keep loved one safety Session 8 : Review of PRST combined with GRI Session 9 : Review of other five fall prevention skills Session 10 : Summary of the program and setting goals Week 4: Telephone visit Session 11 : Booster session and telephone visit Week 10: Evaluation
Study: NCT06383234

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: LG-TAP block with local anesthetic
Description: The laparoscopic guided TAP Block was performed by surgeon at the beginning of surgery, injecting 15 ml of Ropivacaine 0.5% on each side, using an atraumatic needle (10/15 cm length, 20 Gauge diameter) close to the anterior axillary line, between the iliac crest and the subcostal margin. Correct needle tip positioning between the transverse muscle of the abdomen and the internal oblique was verified through laparoscopic guidance.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: LG-TAP block with saline solution
Description: The laparoscopic guided TAP Block was performed by surgeon at the beginning of surgery, injecting 15 ml of Saline solution (NaCl 0.9%) on each side, using an atraumatic needle (10/15 cm length, 20 Gauge diameter) close to the anterior axillary line, between the iliac crest and the subcostal margin. Correct needle tip positioning between the transverse muscle of the abdomen and the internal oblique was verified through laparoscopic guidance.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Port site infiltration
Description: Prior the surgical incision, an infiltration of the laparoscopic access using a total of 10 ml Ropivacaine 0.5% was performed by surgeon

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Port site infiltration
Description: Prior the surgical incision, an infiltration of the laparoscopic access using a total of 10 ml Ropivacaine 0.5% was performed by surgeon
Study: NCT05423496

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: KidneyCare
Description: Using KidneyCare platform as a tool to successfully augment immunosuppressant agents through regular surveillance allowing minimization of doses and number of agents.
Study: NCT06085274

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ICG guided sentinel lymph node biopsy
Description: During sentinel lymph node biopsy the surgeon will inject a volume of 0.1ml divided into 2 doses (0.05ml each) of 2.5mg/mL ICG into the periareolar dermis of the involved breast. Technetium and blue dye will also be administered as per standard of care. The surgeon will assess the axilla with the the SPY-PHI near infrared imaging system to identify and remove ICG-fluorescent nodes; Any other sentinel lymph nodes identified will also be removed as per standard of care. If there is no progression of ICG towards the axilla, or if no ICG sentinel lymph node can be identified, an alternate injection technique involving peritumoural injection at 2-3 locations near the cancer site in the subcutaneous or dermal space of 0.05ml will be utilized.
Study: NCT05423496

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: KidneyCare
Description: Using KidneyCare platform as a tool to successfully augment immunosuppressant agents through regular surveillance allowing minimization of doses and number of agents.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: KidneyCare
Description: Using KidneyCare platform as a tool to successfully augment immunosuppressant agents through regular surveillance allowing minimization of doses and number of agents.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: KidneyCare
Description: Using KidneyCare platform as a tool to successfully augment immunosuppressant agents through regular surveillance allowing minimization of doses and number of agents.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: steroid
Description: optimization of steroids

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MMF
Description: optimization of MMF
Study: NCT05407454

Intervention type: OTHER
Intervention: Questionnaire
Description: The original form of the Diabetes Quality of Life-Brief Clinical Inventory was first developed in 1999 to establish a valid and reliable form of diabetes-specific quality of life. Inventory items were developed to address the issues that have the greatest impact on assessing patient self-care behaviors and satisfaction with diabetes care. Items are ranked on a 5-point Likert scale and are in two general formats. One format includes satisfaction with treatment and quality of life and is scored from 1 (very satisfied) to 5 (not very satisfied). The second format includes the frequency of adverse effects of diabetes itself or diabetes treatment and offers response options from 1 (never) to 5 (always). Therefore, higher scores on the DQL-BCI items and subscales include negative values indicating problem frequency or dissatisfaction. In order to use the DQL scale more efficiently in clinics, Burroughs et al. organized the 15-item DQL-BCI in 2004.
Study: NCT05936931

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Changes in CRC screening awareness and intentions
Description: Using a single arm, open-label, pre-test post-test design (n=15 adult child/parent dyads), assess the impact of a young adult-mediated intervention to increase CRC screening among a paired age-eligible family member (e.g., parent/grandparent). The focus of the intervention will be on changes in CRC screening awareness and intentions among the age-eligible adult, but we hypothesize that the young adult could benefit as well. Thus, in addition to assessing feasibility and acceptability, we will assess changes in 1) CRC screening intentions among the age-eligible adults and 2) CRC health literacy and awareness of screening guidelines among the younger adult participant.
Study: NCT06049264

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thoracic spine manual traction with mobilization protocol.
Description: The therapist will perform one 30-second bout of grade I or II central posterior-anterior mobilization at the T3 spinous process as described by Maitland et al. After the 30-second bout, the therapist proceeded to T4 and performed the same technique. This process was continued sequentially in a caudal direction to T8, for an overall intervention time of approximately 3 minutes. In addition to mobilization, thoracic spine traction will be also given in sitting position.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic manipulation protocol
Description: To perform the manipulation, the stabilizing hand will be placed at the level immediately caudal to the restricted segment using a ''pistol grip''. Once the pre manipulative position will be achieved the patient will be instructed to take a deep inhalation and exhale. During the exhalation the treating clinician performed a high velocity, small amplitude thrust in a direction to facilitate relative closing or opening of the respective facet joint as indicated by the segmental examination.
Study: NCT05346003

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TCSP
Description: In the pre-test, all students will be given a BLS information form, followed by blended e-learning with theory and video in a virtual environment. The BLS knowledge post-test will be administered immediately after class.T-shirts and standard pillows (550 g silicon fiber pillow 50x70 cm size) with a simulation of an adult human size (approximately) sternum, rib and heart drawing (printed as picture) will be given to the intervention group only after the pretest. In the study, the BLS will be simulated for adult patients only. To simulate a half-body human BLS mock-up, a pre-made simulation t-shirt will be fitted on a standard pillow to create a BLS mock-up in a home environment, and after blended e-learning, they will be able to perform BLS iteratively on a T-shirt-clad simulation pillow (TCSP) model. In this way, autonomous learning will be supported. All students will practice BLS in a real simulation model two weeks after the blended e-learning.
Study: NCT05374226

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JS019
Description: Four dose levels are preset: 0.3 mg/kg, 1 mg/kg, 3 mg/kg, and 10 mg/kg. The subjects are treated with JS019 by intravenous infusion, once every 3 weeks (Q3W). A treatment cycle is 21 days, and the DLT observation period is 21 days after the first administration.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JS019
Description: Four dose levels are preset: 0.3 mg/kg, 1 mg/kg, 3 mg/kg, and 10 mg/kg. The subjects are treated with JS019 by intravenous infusion, once every 3 weeks (Q3W). A treatment cycle is 21 days, and the DLT observation period is 21 days after the first administration.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JS019
Description: Four dose levels are preset: 0.3 mg/kg, 1 mg/kg, 3 mg/kg, and 10 mg/kg. The subjects are treated with JS019 by intravenous infusion, once every 3 weeks (Q3W). A treatment cycle is 21 days, and the DLT observation period is 21 days after the first administration.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JS019
Description: Four dose levels are preset: 0.3 mg/kg, 1 mg/kg, 3 mg/kg, and 10 mg/kg. The subjects are treated with JS019 by intravenous infusion, once every 3 weeks (Q3W). A treatment cycle is 21 days, and the DLT observation period is 21 days after the first administration.
Study: NCT05541055

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: digital CBT-I
Description: A fully-automated and personalized digital intervention based on principles from cognitive behavioral therapy for insomnia.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sleep hygiene education
Description: Participants will be provided with sleep hygiene advice which will be delivered digitally all at once upon allocation to the SHE arm. Participants will be able to revisit content during the trial as they wish.
Study: NCT05886140

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carrilizumab with albumin-binding paclitaxel
Description: All enrolled patients received carrilizumab combined with albumin-binding paclitaxel.
Study: NCT05577208

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Symplicity Spyral multi-electrode renal denervation catheter and Symplicity G3 generator (Renal Denervation System)
Description: Minimally invasive percutaneous interventional therapy aimed to modulate the sympathetic nervous system through endovascular ablation of both renal arteries
Study: NCT05624879

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Accelerated Resolution Therapy
Description: A brief psychotherapeutic intervention delivered by trained therapists in a maximum of 4 sessions. Sessions will focus on providing relief from the distress related to an anticipated loss and to shift focus from distress and loss back to the relationship.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information and Support
Description: 4 sessions of a standardized social work intervention. Standard of care including education and active listening.
Study: NCT05025657

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: ALLY
Description: ALLY is a universal, school-based prevention program that takes place during the school day with individual students over 6 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ALLY
Description: ALLY is a universal, school-based prevention program that takes place during the school day with individual students over 6 weeks.
Study: NCT06145243

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home based exercise
Description: Patients will be given a visual brochure with pictures explaining the exercises. Patients will perform the resistance exercises in the given exercise program for 8 weeks, 2 days a week for 8-12 repetitions and 3 sets using resistance bands.Progress of the home exercise group will be checked by phone every week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Video-based resistive exercise
Description: A video recording of the exercises will be taken and given to the patients as a video recording.Patients will perform the resistance exercises in the given exercise program for 8 weeks, 2 days a week for 8-12 repetitions and 3 sets using resistance bands.Progress of the video-based exercise group will be checked by phone every week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised resistive exercise
Description: Patients will perform their exercises under the supervision of a physiotherapist.Patients will perform the resistance exercises in the given exercise program for 8 weeks, 2 days a week for 8-12 repetitions and 3 sets using resistance bands.
Study: NCT05461976

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based self-management exercise program
Description: Session 1 will includes education about stroke. Session 2 will includes feedback on behaviour performance on initial measurement outcomes, health consequences of the physical inactivity, answering an exercise preferences questionnaire, generation of a list of goals, delivering a smartband and a diary to self-monitoring. Session 3 will includes reviewing of goals and strategies to self-monitoring, encouragement, rising barriers to exercise and potential solutions to them, development of a weekly schedule physical exercise, implementation of the physical exercise session with participant and delivering a paper-exercise guide. Session 4 will includes reviewing of goals and weekly schedule physical exercise, encouragement, problem solving/coping planning, reviewing strategies to self-monitoring and showing to participant a video with another stroke survivors which are physically active. Sessions 5 and 6 will be the same as session 4 with exception of vicarious reinforcement.