TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06519838

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthesia solution at room temperature
Description: The local anesthesia cartridge is used at room temperature (average of 21 °C)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthesia solution at room temperature
Description: The local anesthesia cartridge is used at room temperature (average of 21 °C)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Local anesthesia solution pre-warmed to 37°C
Description: About 150 ml of water at 21°C is added to the heating compartment of the heating device. The Local anesthesia cartridge is placed at the bottom of the heating compartment. The device is plugged in and the control gauge is set at the Express milk warming setting for contents up to 180ml/6oz mark. The contents would reach 37°C at 120 seconds.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Local anesthesia solution pre-warmed to 37°C
Description: About 150 ml of water at 21°C is added to the heating compartment of the heating device. The Local anesthesia cartridge is placed at the bottom of the heating compartment. The device is plugged in and the control gauge is set at the Express milk warming setting for contents up to 180ml/6oz mark. The contents would reach 37°C at 120 seconds.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Local anesthesia solution pre-warmed to 40°C
Description: About 150 ml of water at 21°C is added to the heating compartment of the heating device. The Local anesthesia cartridge is placed at the bottom of the heating compartment. The device is plugged in and the control gauge is set at the Express milk warming setting for contents up to 180ml/6oz mark. The contents would reach 40°C at 130 seconds.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Local anesthesia solution pre-warmed to 40°C
Description: About 150 ml of water at 21°C is added to the heating compartment of the heating device. The Local anesthesia cartridge is placed at the bottom of the heating compartment. The device is plugged in and the control gauge is set at the Express milk warming setting for contents up to 180ml/6oz mark. The contents would reach 40°C at 130 seconds.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary infiltration technique
Description: A 30 gauge short needle is oriented so that the bevel is facing the bone. The syringe is held parallel to the long axis of the tooth and the needle is inserted into the height of the mucobuccal fold over the offending tooth. The needle is advanced to a depth of 1 millimeter into the tissues. Aspiration is done, and once it is negative then 0.6 ml (nearly one third of the cartridge) of the anesthetic solution is injected slowly without permitting the tissues to balloon.
Study: NCT05548660

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacogenetic testing
Description: Genetic testing of CYP2B6, CYP2C19, CYP2C9, CYP2C cluster CYP2D6, CYP3A5, CYP4F2, DPYD, HLA-A, HLA-B, IFNL4, NUDT15, SLCO1B1, TPMT, UGT1A1, and VKORC1.

Intervention type: OTHER
Group type: OTHER
Intervention: Pharmacogenetic testing
Description: Genetic testing of CYP2B6, CYP2C19, CYP2C9, CYP2C cluster CYP2D6, CYP3A5, CYP4F2, DPYD, HLA-A, HLA-B, IFNL4, NUDT15, SLCO1B1, TPMT, UGT1A1, and VKORC1.
Study: NCT06519838

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maxillary infiltration technique
Description: A 30 gauge short needle is oriented so that the bevel is facing the bone. The syringe is held parallel to the long axis of the tooth and the needle is inserted into the height of the mucobuccal fold over the offending tooth. The needle is advanced to a depth of 1 millimeter into the tissues. Aspiration is done, and once it is negative then 0.6 ml (nearly one third of the cartridge) of the anesthetic solution is injected slowly without permitting the tissues to balloon.
Study: NCT05548660

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacist note with genotype-guided analgesic recommendations
Description: CYP2C9 normal metabolizers will be recommended to receive ibuprofen and intermediate and poor metabolizers will be recommended to receive naproxen.~CYP2D6 normal metabolizers will be recommended to receive tramadol and ultrarapid, intermediate and poor metabolizers will be recommended to receive oxycodone.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines
Description: Genotype-guided recommendations for all actionable phenotypes resulted from the 16-gene PGx panel per CPIC guidelines and FDA labeling
Study: NCT06519838

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maxillary infiltration technique
Description: A 30 gauge short needle is oriented so that the bevel is facing the bone. The syringe is held parallel to the long axis of the tooth and the needle is inserted into the height of the mucobuccal fold over the offending tooth. The needle is advanced to a depth of 1 millimeter into the tissues. Aspiration is done, and once it is negative then 0.6 ml (nearly one third of the cartridge) of the anesthetic solution is injected slowly without permitting the tissues to balloon.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Inferior alveolar nerve block technique
Description: While the mouth is opened as wide as possible, the index finger palpates the external oblique ridge reaching the Coronoid notch. A 27-gauge long dental needle will be used for injection. The needle will be directed between the two primary molars on the opposing side of the arch, penetrating the tissues at the point halfway between coronoid notch and the pterygomandibular raphe at the occlusal plane level or slightly lower.The needle is withdrawn 2mm to aspirate. Once negative aspiration is checked, the remainder of the solution is deposited slowly. Approximately 1.0 mL of LA will be delivered near the inferior alveolar nerve. The average depth of insertion is about 15mm, which is nearly two-thirds the needle length.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inferior alveolar nerve block technique
Description: While the mouth is opened as wide as possible, the index finger palpates the external oblique ridge reaching the Coronoid notch. A 27-gauge long dental needle will be used for injection. The needle will be directed between the two primary molars on the opposing side of the arch, penetrating the tissues at the point halfway between coronoid notch and the pterygomandibular raphe at the occlusal plane level or slightly lower.The needle is withdrawn 2mm to aspirate. Once negative aspiration is checked, the remainder of the solution is deposited slowly. Approximately 1.0 mL of LA will be delivered near the inferior alveolar nerve. The average depth of insertion is about 15mm, which is nearly two-thirds the needle length.
Study: NCT05548660

Intervention type: OTHER
Group type: OTHER
Intervention: Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines
Description: Genotype-guided recommendations for all actionable phenotypes resulted from the 16-gene PGx panel per CPIC guidelines and FDA labeling
Study: NCT06519838

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inferior alveolar nerve block technique
Description: While the mouth is opened as wide as possible, the index finger palpates the external oblique ridge reaching the Coronoid notch. A 27-gauge long dental needle will be used for injection. The needle will be directed between the two primary molars on the opposing side of the arch, penetrating the tissues at the point halfway between coronoid notch and the pterygomandibular raphe at the occlusal plane level or slightly lower.The needle is withdrawn 2mm to aspirate. Once negative aspiration is checked, the remainder of the solution is deposited slowly. Approximately 1.0 mL of LA will be delivered near the inferior alveolar nerve. The average depth of insertion is about 15mm, which is nearly two-thirds the needle length.
Study: NCT04751695

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CoronoVac Vaccine
Description: CoronaVac vaccines will be inoculated in 2 doses with an interval of 24 days.
Study: NCT05679245

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment for exposure to psychological trauma and related symptoms
Description: To be assessed for exposure to traumatic life events, post-traumatic stress disorder, trauma-related symptoms, dissociative symptoms, affective symptoms, and psychosocial functioning.
Study: NCT06073457

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MagGJ System
Description: Anastomoses achieved by magnetic compression.
Study: NCT05343169

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Overdose Education and Naloxone Distribution
Description: Education on OD risk behaviors and methods for responding to an OD, including naloxone use.~Duration and dose: Single 20-minute training at time of enrollment, provided to all participants in both arms

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Overdose Education and Naloxone Distribution
Description: Education on OD risk behaviors and methods for responding to an OD, including naloxone use.~Duration and dose: Single 20-minute training at time of enrollment, provided to all participants in both arms

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Advanced Education in Safer Substance Use, Treatment, and Self-Care
Description: Education about misinformation about OAT, self-care, SEP services, HIV/HCV treatment Duration/dose: 9 mos., monthly \~2 hr. group sessions + ongoing access to video archive of recorded trainings.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Service and Health Navigation
Description: Help navigate access and barriers to healthcare, motivation and health goals Duration/dose: 9 mos., monthly face-to-face sessions to set goals and schedule appts, phone calls between sessions \> 1x/wk.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Social Support
Description: Support with social (re)integration, isolation, relationship building Duration/dose: 9 mos., monthly face-to-face events and phone calls/texts between sessions \> 1x/wk.
Study: NCT06233890

Intervention type: DEVICE
Intervention: Motion watch
Description: Actigraphy watch to be worn for 14 days

Intervention type: DEVICE
Intervention: Motion watch
Description: Actigraphy watch to be worn for 14 days
Study: NCT06532734

Intervention type: DEVICE
Intervention: EsoGuard
Description: device used to collect esophageal cell samples to test for the presence of abnormal cells which may indicate a dx of Barrett's esophagitis.
Study: NCT05512689

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ventilations while using a respiratory function monitor
Description: Healthcare professionals are able to use a feedback device to guide their ventilations.
Study: NCT06024434

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercises
Description: Experimental Group Exercises for Core: Crunches, Glute bridges Crunches Glute bridge Week 1-2 (set/rep/sec) Week 3-4 (set/rep/sec) Week 5-6 (set/rep/sec) Exercises for upper body: Push up (4), Bicep curls Exercises Weeks Reps/sets Push up walk out Bicep curls 1-3 16-20\*3 Push up Bicep curl with Dumbbell 4-6 12-15\*3 Exercises for Lower body: Lunges and Squats Exercises Weeks Reps/set Split Squat with body weight Body weight Squat 1-3 16-20\*3 Split Squat with Dumbbell Squat with Dumbbell 4-6 12-15\*

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walking
Description: Walking for 30min, 5 days a week
Study: NCT05616676

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief digital imagery-competing task
Description: First session guided by a researcher: A memory cue followed by playing a computer game with mental rotation instructions.~Option to engage in self-administered/guided sessions after the first session.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief digital music-listening task
Description: First session guided by a researcher: Information about the composer's music followed by listening to classical music.~Option to engage in self-administered/guided sessions after the first session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment As Usual
Description: Access to routine care that participants would otherwise receive if having intrusive memories of traumatic events.
Study: NCT06611982

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unconditional cash transfer
Description: $1000/month for 12 months

Intervention type: OTHER
Group type: OTHER
Intervention: Contact information for social worker and financial counselor
Description: Information on financial toxicity and contact information for social worker and financial counselor
Study: NCT04940156

Intervention type: DEVICE
Group type: OTHER
Intervention: Confirm Rx (Implantable Cardiac Monitor)
Description: Confirm Rx implanted in patients with atrial fibrillation detected on their cardiac implantable electronic device (CIED)

Intervention type: DEVICE
Group type: OTHER
Intervention: Reveal LINQ (Implantable Cardiac Monitor)
Description: Reveal LINQ implanted in patients with atrial fibrillation detected on their cardiac implantable electronic device (CIED)
Study: NCT04862260

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cholesterol metabolism disruption
Description: Cholesterol metabolism disruption using a combination of atorvastatin, ezetimibe and evolocumab in metastatic pancreatic adenocarcinomas
Study: NCT04235400

Intervention type: DIAGNOSTIC_TEST
Intervention: No Dye BreakUp Time
Description: Measurement without dye of the tear meniscus height (TMH) which give an rapid hint on the quantity of tears present on the ocular surface, the measure in real time of the tear osmolarity and, at last, the analysis of the thickness of the tear's layer by interferometry (measurement of the light fringes reflected by the tears when illuminated with polarized light, whereby the complete layer or the lipid layer alone can be evaluated separately depending on the machines used) and of the assessment of the quality of the Meibomian glands (non-contact imaging by infrared illumination).
Study: NCT06380205

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Povorcitinib
Description: Povorcitinib will be administered at protocol defined dose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levonorgestrel/Ethinyl estradiol
Description: Levonorgestrel/Ethinyl estradiol will be administered at protocol defined dose.
Study: NCT03714477

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extracorporeal shock wave lithotripsy
Description: A minimally invasive treatment for renal stone which was first introduced in early 1980's. It tries to fragment the renal stones by high-energy shockwave at the kidney from the outside.
Study: NCT05710146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: 1 injection of 15mg/kg of TXA in 100mL of normal saline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 injection of 100mL of normal saline
Study: NCT03902093

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Morphology changes with extended wear hearing aid
Description: Possible changes in morphology due to wearing an extended wear hearing aid device will be assessed with imaging
Study: NCT06017401

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Oblique Subcostal Transversus Abdominis Plane Block
Description: The investigator will perform oblique subcostal transversus abdominis plane block to that patient group for postoperative analgesia

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transmuscular Quadratus Lumborum Block
Description: The investigator will perform transmuscular quadratus lumborum block to that patient group for postoperative analgesia
Study: NCT05914818

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EXPLORER V2
Description: 4 sessions of use of the exoskeleton, 1 in a laboratory of gait analysis and 3 in the home and the community of the participants
Study: NCT04826159

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMB-1018972
Description: Modified release tablet for oral administration
Study: NCT06133140

Intervention type: DEVICE
Intervention: Unblinded postoperative vital sign monitoring
Description: Unblinded postoperative GE Portrait monitoring

Intervention type: DEVICE
Intervention: Blinded postoperative vital sign monitoring
Description: Blinded postoperative GE Portrait monitoring
Study: NCT06422169

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ArToFILL
Description: ArToFILL is an injectable medical device (class III) intended for use as a temporary filler in joints. It is a sterile, non-pyrogenic, colorless and transparent hyaluronic acid gel of non-animal origin. ArToFILL is a hydrogel consisting of a mixture of two different molecular weights of hyaluronic acid, for a total HA concentration of 2.7 %.
Study: NCT05118347

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Buteyko Breathing Technique
Description: An incentive spirometer is a device that measures how deeply you can inhale (breathe in). It helps you take slow, deep breaths to expand and fill your lungs with air. This helps prevent lung problems, such as pneumonia. The incentive spirometer is made up of a breathing tube, an air chamber, and an indicator.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Buteyko Breathing Technique
Description: An incentive spirometer is a device that measures how deeply you can inhale (breathe in). It helps you take slow, deep breaths to expand and fill your lungs with air. This helps prevent lung problems, such as pneumonia. The incentive spirometer is made up of a breathing tube, an air chamber, and an indicator.
Study: NCT05852314

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally Adapted Manual Assisted Therapy (CMAP-SI)
Description: C-MAP has been adapted from a self-help guide called Life After Self-Harm based on the principles of CBT. It is a brief problem-solving therapy comprising have 4 sessions weekly and then 4 fortnightly and last about 50 minutes each. The manual has been translated to Urdu giving special consideration to cultural adaptation of phrases and concepts to reflect Pakistani culture. Additionally, culturally appropriate case scenarios were incorporated and a consensual view to addressing cultural factors such as gender role, family conflicts and financial difficulties was taken. The culturally adapted intervention consists of the following components: evaluation of self-harm attempt, crisis skills, problem-solving and CBT techniques to manage emotions, negative thinking, interpersonal relationships, and relapse prevention strategies. Participants will receive sessions according to adapted CMAP-SI manual.
Study: NCT06398236

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: SE5-OH tablets
Description: SE5-OH (Fermented Soy germ, include S-equol), Crystalline cellulose, Oats fiber, Agar, Cyclic oligosaccharide, HPMC, Reduced syrup.
Study: NCT06202144

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Noninvasive support
Description: Noninvasive respiratory support delivered through a helmet

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Noninvasive support
Description: Noninvasive respiratory support delivered through a helmet

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Noninvasive support
Description: Noninvasive respiratory support delivered through a helmet
Study: NCT05216445

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Training
Description: The Mindfulness Training will be an 8-week course, with group-based online weekly sessions. The mindfulness training, translated and adapted in Urdu, includes 8 guided audio meditations and one introductory audio recording which gives the participants an overview and introduction of the forthcoming 8-week training (e.g what mindfulness is, some common terms used repeatedly). It also includes 8 chapters, corresponding to each week and a workbook to record home practice. The training will start with an online group session after which the participants will be emailed the 1st week's reading material (chapter 1), audio recordings (for that week), home practice (for that week). At the start of every week, the participants will be emailed the required material for that week. Online sessions will be conducted weekly. The participants will also be sent poems and/or quotations relating to the week's theme and based on the session proceedings.
Study: NCT05269368

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Wicking
Description: Absorbable or non-absorbable wicking

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: No wicking
Description: No wicking after surgery
Study: NCT06203821

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NP137
Description: NP137 for the Treatment of Resectable Pancreatic Cancer
Study: NCT04611542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fathering In Recovery
Description: Fathering In Recovery (FIR) will be designed to address the unique needs of fathers in treatment for opioid misuse. FIR integrates evidence-based parenting interventions that have well-documented positive outcomes on children, parents, and families, with innovative web-based mobile technology to maximize accessibility, fidelity, and consistency of intervention and support.
Study: NCT05720559

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Oxaliplatin via intravenous drip on d1 at a dose of 130mg/m2 × patient 's body surface area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Oxaliplatin via intravenous drip on d1 at a dose of 130mg/m2 × patient 's body surface area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S1
Description: Orally on d2-d15 at 20 mg three times daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: Cetuximab combined with chemotherapy was administered simultaneously, once every three weeks,and intravenous drip was performed before oxaliplatin at a dose of 250 mg/m2 × body surface area.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metronidazole
Description: Metronidazole 0.4g/time, qd

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin A
Description: Vitamin A 25,000 units/time, qd

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Folic acid
Description: Folic acid 0.4 mg/time, qd

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine via orally on d2-d15 two times daily at a dose of 1000mg/m2 × patient 's body surface area.