TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05877885

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted Cognitive Training Intervention
Description: In this intervention, participants will complete 25-30 minutes of cognitive training per day, 5 days/week (but up to 7 days/week) for 4 weeks. The training protocol will be delivered via the Posit Science Platform, and includes tasks that emphasize training of sustained attention, salience detection, and dimensions of cognitive control. During the 4 week intervention, participants will have weekly 10-20 minute visits with a Care Manager to provide clinical monitoring of symptoms and structured support to participants.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General Cognitive Training Intervention
Description: In this intervention, participants will complete 25-30 minutes of cognitive activities per day, 5 days/week (but up to 7 days/week) for 4 weeks. The training protocol will be delivered via the Posit Science Platform. The intervention protocol will include computerized cognitive activities designed to provide general cognitive stimulation. During the 4 week intervention, participants will have weekly 10-20 minute visits with a Care Manager to provide clinical monitoring of symptoms and structured support to participants.
Study: NCT06509152

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Theory of mind-based social competence group intervention
Description: The ToM-SCGI is designed as a group intervention, with 60-minute sessions held weekly, either once or twice, and led by trained therapists. Two caregiver meetings are conducted in the middle and end of the interventions.~The intervention process for each session is as follows:~1. Warm-up Activities(5-10 minutes): review the previous group session and prepare for the current group activities.~2. Theory of Mind Instruction(10-15 minutes): based on the developmental stage of the children's theory of mind, using thought bubbles to teach corresponding elements of theory of mind development.~3. Social Skills Group Games(30-35 minutes): design social scenario-based group games that allow children to practice applying the acquired theory of mind abilities into expressions and applications of theory of mind and social competence.~4. Summary(5-10 minutes): summarize the children's performance in the group and assign homework.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Theory of mind-based social competence group intervention
Description: The ToM-SCGI is designed as a group intervention, with 60-minute sessions held weekly, either once or twice, and led by trained therapists. Two caregiver meetings are conducted in the middle and end of the interventions.~The intervention process for each session is as follows:~1. Warm-up Activities(5-10 minutes): review the previous group session and prepare for the current group activities.~2. Theory of Mind Instruction(10-15 minutes): based on the developmental stage of the children's theory of mind, using thought bubbles to teach corresponding elements of theory of mind development.~3. Social Skills Group Games(30-35 minutes): design social scenario-based group games that allow children to practice applying the acquired theory of mind abilities into expressions and applications of theory of mind and social competence.~4. Summary(5-10 minutes): summarize the children's performance in the group and assign homework.
Study: NCT06417190

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trimodal therapy (TMT) within 45 days of neoadjuvant chemotherapy (NAC)
Description: Single-arm, open-label
Study: NCT06272253

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: INAVAC (Vaksin Merah Putih - UA- SARS CoV-2 (Vero Cell Inactivated) 5 μg
Description: Dose : 1 dose 0.5 ml containing 5 μg inactivated SARS-CoV-2 virus, Tween 80, histidine, Polysorbate 80, Aluminium hydroxide gel, and sodium chloride.
Study: NCT05535868

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SPN3 innoculation
Description: Healthy adult participants aged 18-50 (inclusive) will be inoculated with pure culture of well-characterised, fully sequenced amoxicillin-sensitive SPN3. They will be observed for safety and development of pneumococcal colonisation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SPN3 innoculation
Description: Healthy adult participants aged 18-50 (inclusive) will be inoculated with pure culture of well-characterised, fully sequenced amoxicillin-sensitive SPN3. They will be observed for safety and development of pneumococcal colonisation
Study: NCT04739735

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dental Local Anaesthesia
Description: lower primary molar teeth indicated for extraction will be given a local anaesthetic injection according to the random allocation to one of the two arms mentioned previously
Study: NCT06675981

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Shallow acupuncture at real-acupoint
Description: At the same acupoint in the acupuncture group, the subcutaneous puncture is only 1-2 mm, no manipulation will be applied

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Shallow acupuncture at non-meridian and non-acupoint
Description: At non-meridian and non-acupoint, the subcutaneous puncture is only 1-2 mm, no manipulation will be applied
Study: NCT04105920

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic acid arm
Description: Patients included in this arm, will have, before insertion of brachytherapy seeds in the prostate, an injection of hyaluronic acid between the prostate, rectum, and pudendal arteries
Study: NCT04739735

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dental Local Anaesthesia
Description: lower primary molar teeth indicated for extraction will be given a local anaesthetic injection according to the random allocation to one of the two arms mentioned previously
Study: NCT04105920

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyaluronic acid arm
Description: Patients included in this arm, will have, before insertion of brachytherapy seeds in the prostate, an injection of hyaluronic acid between the prostate, rectum, and pudendal arteries
Study: NCT05656638

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Speech and language therapy
Description: The treatment focuses on grammatical time marking. The aim of the treatment is to train underlying grammatical time marking processes, which were identified as deficient during a preliminary evaluation. The intervention is composed of 4 steps inspired by models and hypotheses from the literature on the subject. Step 1: temporal adverbial selection, subject must identify the tense encoded in sentences and select the correct adverbial among those proposed. Step 2: selection of inflected verb forms, subject must identify the tense encoded in the sentence and select the correct verb form among those proposed. Step 3: production of inflected verb forms, subject must identify the tense encoded in the sentence and produce inflected verbs. Step 4: semantic narration, subject must describe scenes using verbs inflected according to the previously defined reference time.
Study: NCT06618534

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azithromycin
Description: A standard dose of azithromycin (500 mg) will be delivered by oral route.
Study: NCT05183009

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: eXciteOSA
Description: eXciteOSA
Study: NCT05176080

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib
Description: Famitinib orally, daily or every other day
Study: NCT06679660

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: inferior alveolar nerve block with 4% articaine
Description: A single ampoule of 4% articaine was administered to a cohort of patients presenting with irreversible pulpitis in the first or second mandibular premolars, designated for Inferior Alveolar Block anesthesia via the mandibular foramen.
Study: NCT05176080

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6390
Description: SHR6390 orally, daily for 3 weeks followed by 1 week off

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fulvestrant
Description: Fulvestrant
Study: NCT05203510

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Parenteral Treprostinil
Description: Parenteral treprostinil will be administered per schedule specified in the arm description.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral Treprostinil
Description: Oral treprostinil will be administered per schedule specified in the arm description.
Study: NCT06679660

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mental/Incisive Nerve Block (%4 Articaine)
Description: A single ampoule of 4% articaine was administered to a cohort of patients presenting with irreversible pulpitis in the first or second mandibular premolars, designated for Mental or Incisive Nerve Block anesthesia via the mental foramen.
Study: NCT06689696

Intervention type: DEVICE
Intervention: miLens system
Description: The miLens system consists of the miLens contact lens made of soft, biocompatible materials, the miLens imaging system, and miLens analysis software.

Intervention type: DEVICE
Intervention: miLens system
Description: The miLens system consists of the miLens contact lens made of soft, biocompatible materials, the miLens imaging system, and miLens analysis software.

Intervention type: DEVICE
Intervention: miLens system
Description: The miLens system consists of the miLens contact lens made of soft, biocompatible materials, the miLens imaging system, and miLens analysis software.
Study: NCT06691841

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chlorhexidine Gluconate
Description: oral wiping and oral care solution rinsing, oral care solution was 0.12% chlorhexidine gluconate, and the frequency of oral care was 3 times a day.

Intervention type: OTHER
Group type: OTHER
Intervention: normal saline
Description: oral wiping and oral care solution rinsing, oral care solution was 0.9% normal saline, and the frequency of oral care was 3 times a day.
Study: NCT06689293

Intervention type: DIAGNOSTIC_TEST
Intervention: Faecal Immunochemical Test
Description: Self-collected sample from stool collected into testing kit
Study: NCT06695689

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM303
Description: Treatment with LM303 injection
Study: NCT05276648

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CAM ICU test
Description: CAM ICU for delirium
Study: NCT05025488

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peptide-based vaccine
Description: ten (10) doses of Mutant-CALR peptides with KLH as helper peptide (in the first vaccine only). Mutant-CALR vaccine will administered every 2 weeks for the first 4 doses and then every 4 weeks for additional 6 doses. Maintenance Treatment The protocol allows for a continued administration of up to four (4) additional Mutant-CALR vaccine and four (4) Poly-ICLC administrations, 12 weeks apart.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Poly ICLC
Description: ten (10) doses of Poly-ICLC. Poly-ICLC will be given on weeks 1, 3, 5, 7, 11, 15, 19, 23, 27 and 31. each Poly-ICLC dose must be given the day after the corresponding Mut-CALR vaccination.
Study: NCT06150196

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Stress Reduction class
Description: 9-week standard Mindfulness-based Stress Reduction class training on mindfulness techniques, medication, and yoga

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brain Health Education class
Description: 9-week Brain Health education class that involves lectures/discussion about how the brain works and recovers after brain injury
Study: NCT06687512

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SaaTwae Bio-Natural Moisturizing Cream
Description: Mode of Usage: Apply a generous amount of the test product to the affected areas of atopic dermatitis. Gently massage the product into the skin until fully absorbed. Ensure that the application is consistent, especially after bathing or during flare-ups.~Frequency: Twice a day (Once before going to the bed and once after bathing and drying off and during flare ups/itching) Route of Administration: Topical

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Mode of Usage: Apply a generous amount of the test product to the affected areas of atopic dermatitis. Gently massage the product into the skin until fully absorbed. Ensure that the application is consistent, especially after bathing or during flare-ups.~Frequency: Twice a day (Once before going to the bed and once after bathing and drying off and during flare ups/itching) Route of Administration: Topical
Study: NCT06689891

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pelvic Floor Muscle Therapy Website
Description: 8-week video-based, self-directed PFMT course
Study: NCT06685965

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RE03
Description: Buccal Dexmedetomidine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RE03
Description: Buccal Dexmedetomidine

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo
Study: NCT06688760

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Low Dose Radiotherapy
Description: in experimental arm 1

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Low Dose Radiotherapy
Description: in experimental arm 1

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Double upper neck lymph node dissection
Description: in experimental arm 2
Study: NCT06688825

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education regarding Weight loss
Description: Per American Association of Clinical Endocrinology (AACE) guidelines

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle tools for weight loss
Description: Calorie App, Continuous GlucosWe Monitor (CGM), Weight Scale, Food Scale

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood draw
Description: Per American Association of Clinical Endocrinology (AACE) guidelines
Study: NCT06686225

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bowen's technique.
Description: This group will receive 20 mint per session for 6 weeks of bowen's technique.~* Frequency: 3-5 days per week for 6 days~* Intensity: moderate to high intensity of soft tissue mobilization~* Time: 20 mints~* Type: Bowen's technique

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan bent leg raise technique
Description: This group will receive 15 mints per session for 6 weeks of mulligan's bent leg raise technique.~* Frequency: 3-5 days per week for 6 days~* Intensity: moderate to high intensity of soft tissue mobilization~* Time: 15 mints~* Type: Mulligan bent leg raise technique
Study: NCT06689345

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: taVNS - transauricular vagal nerve stimulation
Description: 30 minutes of electrical stimulation on the afferent portion of the vagal nerve on the cymba conchae of the ear, in the following configuration: 30 seg ramp up, 30 seg on, 30 seg off in intensity on which the volunteer feels a light tingling.

Intervention type: DEVICE
Group type: OTHER
Intervention: taVNS - transauricular vagal nerve stimulation
Description: 30 minutes of electrical stimulation on the afferent portion of the vagal nerve on the cymba conchae of the ear, in the following configuration: 30 seg ramp up, 30 seg on, 30 seg off in intensity on which the volunteer feels a light tingling.

Intervention type: DEVICE
Group type: OTHER
Intervention: rPMS - repetitive peripheric magnetic stimulation
Description: Magnetic stimulation on the efferent portion of the vagal nerve on the neck, on the following configuration: 20Hz, 25 pulses in the trein, in every inhalation, for 20 inhalations with 50% of machine capacity (500 pulses total).

Intervention type: DEVICE
Group type: OTHER
Intervention: rTMS - repetitive transcranial magnetic stimulation
Description: rTMS intermitent theta- burst on the left DLPFC, on the following configuration: 50 Hz in treins of 5Hz, with 110% of the resting motor limiar and 600 pulses in 3 minutes.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: taVNS sham
Description: Simulated taVNS (SHAM) on helix left ear, that is the same as taVNS, but during only 1 minute

Intervention type: DEVICE
Group type: OTHER
Intervention: taVNS sham
Description: Simulated taVNS (SHAM) on helix left ear, that is the same as taVNS, but during only 1 minute
Study: NCT06695273

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: AI-derived probability of coronary heart disease.
Description: Physician readers will be assisted with AI-derived probability of coronary heart disease. The AI tool provides individualized obstructive CHD probabilities and diagnosis, leveraging retinal biomarkers associated with cardiovascular risk.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: PCEs derived ASCVD risk
Description: Physicians use a PCEs to calculate the probability of 10 year ASCVD risk. This approach aligns with current clinical guidelines to assist in decision-making.
Study: NCT06695468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levobupivacaine
Description: 40-ml mixture of 20 ml of 0.5% levobupivacaine diluted with 20 ml of 0.9% N.S. (20 ml to be injected on each side

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levobupivacaine + Dexmedetomidine
Description: 60 ml mixture of 1.5 mic/kg dexmedetomidine added to 30 ml of 0.5% levobupivacaine diluted with 30 ml of 0.9% N.S. (30 ml to be administered on each side, divided into 15 ml for the upper segment and 15 ml for the lower segment).
Study: NCT06695481

Intervention type: PROCEDURE
Intervention: Conventional RF
Description: The conventional RF group consists of patients who received medial branch RF with a duration of 2 minutes, at 80̊ C temperature, and 7 Volts.

Intervention type: PROCEDURE
Intervention: Combined RF
Description: In the combined RF group, treatment was initiated first with a conventional RF duration of 2 minutes at a temperature of 80̊ C at 7 Volts. Then, pulsed RF duration was applied for 6 minutes at a temperature of 42 C at 45 Volts, with a pulse frequency of 2 Hz and a width of 20 ms.
Study: NCT06686810

Intervention type: PROCEDURE
Intervention: Endoscopic Retrogradade CholangioPancreatography (ERCP)
Description: ERCP is an endoscopic therapeutic procedure to drain the bile ducts in case of stones or biliary strictures that can be treated by balloon dilatation or stents (plastic or metal) insertion
Study: NCT06694363

Intervention type: BIOLOGICAL
Intervention: Blood samples
Description: A maximum of 27 ml of blood collected at each visit for metabolic markers analysis

Intervention type: BIOLOGICAL
Intervention: Blood samples
Description: A maximum of 27 ml of blood collected at each visit for metabolic markers analysis

Intervention type: BIOLOGICAL
Intervention: Urine samples
Description: One urine sample collected at each visit for enteric virus infection research

Intervention type: BIOLOGICAL
Intervention: Urine samples
Description: One urine sample collected at each visit for enteric virus infection research

Intervention type: BIOLOGICAL
Intervention: Stool samples
Description: One stool sample collected at each visit for enteric virus infection research

Intervention type: BIOLOGICAL
Intervention: Stool samples
Description: One stool sample collected at each visit for enteric virus infection research
Study: NCT05276648

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: CAM ICU test
Description: CAM ICU for delirium

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MOCA test
Description: MOCA for cognitif disfonction

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MOCA test
Description: MOCA for cognitif disfonction

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: brief pain test
Description: BRİEF PAİN for chronic pain

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: brief pain test
Description: BRİEF PAİN for chronic pain

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: VAS scale
Description: VAS scale for acute pain

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: VAS scale
Description: VAS scale for acute pain
Study: NCT05413278

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Behavioral
Description: Patient education, information and empowerment