TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06426199

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chitosan-Hyaluronate Gel Mixture
Description: The operation will be under GA. TMJ arthroscopy will performed by the same TMJ arthroscopy surgeon. Lysis and lavage will be performed in the upper joint space in all cases based on the triangulation technique with an inferolateral approach. The arthroscopic procedure will include lysis of adhesions, lavage, manipulation, and debridement of the upper joint space. A 1.9-mm arthroscope with a video monitoring and recording system and a 2.2-mm protective cannula sheath will be used for TMJ arthroscopy. Ringer's lactate will be used as irrigation fluid. Both groups will receive the same arthroscopic treatments. The injection of 2 ml of Chitosan-Hyaluronate Gel Mixture into affected joints will be performed. Needles will be removed after the injection sites and covered its sites with gauze dressing.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic Acid
Description: The operation will be under GA. TMJ arthroscopy will performed by the same TMJ arthroscopy surgeon. Lysis and lavage will be performed in the upper joint space in all cases based on the triangulation technique with an inferolateral approach. The arthroscopic procedure will include lysis of adhesions, lavage, manipulation, and debridement of the upper joint space. A 1.9-mm arthroscope with a video monitoring and recording system and a 2.2-mm protective cannula sheath will be used for TMJ arthroscopy. Ringer's lactate will be used as irrigation fluid. Both groups will receive the same arthroscopic treatments. The injection of 2 ml of Hyaluronic acid into affected joints will be performed. Needles will be removed after the injection sites and covered its sites with gauze dressing.
Study: NCT06166225

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-based weight loss program
Description: 12-month, automated and behaviorally-based, Internet-delivered weight loss and weight loss maintenance program

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Internet-based weight loss program
Description: 12-month, automated and behaviorally-based, Internet-delivered weight loss and weight loss maintenance program

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yoga
Description: 9-month Iyengar yoga program consisting of live (Zoom) yoga classes delivered 1-2 times per week during months 4-12, and self-guided yoga practice recommendations.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health and Wellness
Description: 9-month health and wellness program consisting of live (Zoom) yoga classes delivered 1-2 times per week during months 4-12.
Study: NCT04369495

Intervention type: OTHER
Intervention: BAFF serum levels
Description: BAFF levels in serum in visit 0,1,2 during induction therapy

Intervention type: OTHER
Intervention: BAFF serum levels
Description: BAFF levels in serum in visit 0,1,2 during induction therapy
Study: NCT04654091

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryoteraphy with liquid nitrogen
Description: Weekly, at each visit, before applying the treatment, a debridement of the hyperkeratotic tissue covering the wart will be performed with a scalpel handle of number 3 and a scalpel blade of number 15, and then the treatment will be applied.~Subsequently, the application of cryotherapy with liquid nitrogen will be carried out using CryoPen b® (HO Equipment, Hhislenghien-Belgium). To analyze the homogeneous application in all the patients in the study, perform 2 applications of 15 seconds per session, with an interval of 30 seconds between each application, such and as manufacturers recommend. The number of sessions in which the product is applied will be a maximum of 5, following the procedure of previous studies.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nitric-zinc complex
Description: Weekly, at each visit, before applying the treatment, a debridement of the hyperkeratotic tissue covering the wart will be performed with a scalpel handle of number 3 and a scalpel blade of number 15, and then the treatment will be applied.~Subsequently, the application of nitric acid-zinc complex with Verrutop® (Isdin, Barcelona-Spain) will be carried out. The preparation is applied by making small touches with the applicators included in the product.~The number of sessions in which the product is applied will be a maximum of 5, following the recommendations of the manufacturers in the product data sheet.
Study: NCT06330597

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography and lung ultrasound
Description: All patients will undergo non-invasive echocardiogram and lung ultrasound at times of assessment of hemodynamic parameters as needed by usual clinical management.
Study: NCT04754165

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Immersive Relaxation
Description: The VR software developed allows patients to select from scenery such as mountains, the beach or from a selection of short videos, which are intended to promote relaxation.
Study: NCT06027138

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: blood flow resistance training
Description: Muscle size and explosive power was determined by measuring the diameter of its arm and thigh muscles and performing 1RM testing in barbell parallel back squats and foot barbell Bench press ,vertical jump test and timed push ups and pull up tests .secondly treat the arm and thigh muscles to to blood flow resistance training and is administered for approx 2 months a frequency of four times per week at an intensity of seventy five to eight five percent for 4 to 12 reps,1 to 5 sets, at interval of 30 to 40 sec.then determine the impact of treatmnt measurement was again carried out on the circumference and explosive strength of arm and thigh muscles.
Study: NCT05550740

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RLRL
Description: In addition to SVS with power for correcting distance refraction, RLRL will be performed twice per school day with an interval of at least 4 hours, each treatment last 3 minutes.
Study: NCT06400394

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hydrocyn Aqua®
Description: The study solution comes in a liquid form containing hypochlorous acid (HOCl) in a concentration of 0.003%. It is used as a topical agent for wound and peritoneal lavage before wound closure

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: aqueous solution of electrolytes and other hydrophilic molecules
Study: NCT04709055

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Co-management
Description: Personalized and intensive geriatric peri-operative care

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Pre-operative and post-operative geriatric care as per usual practice
Study: NCT05491031

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: magnetic resonance spectroscopy
Description: Investigation of the association, in patients with multiple sclerosis, between MRI biomarker data at inclusion and progression of physical disability during follow-up (6, 12, 18 and 24 months) assessed by a composite endpoint EDSS plus (EDSS, 9HPT, T25FW)
Study: NCT04660214

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: septotomy
Description: endoscopic diverticulotomy

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: septotomy
Description: endoscopic diverticulotomy
Study: NCT05473260

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: In-patient care.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental
Description: Early discharge and outpatient follow-up.
Study: NCT05793723

Intervention type: DIAGNOSTIC_TEST
Intervention: Pulmonary function testing device
Description: Patients will undergo pulmonary function tests with the Exhalyzer D (Ecomedics, Switzerland) device. This device consists of 1) an ultrasonic flow measuring system for measuring flow, volume and molecular mass, 2) a nitrogen washout system to measure functional residual capacity (FRC) and other indices, 3) a carbon dioxide infrared measurement device for monitoring the level of carbon dioxide in exhaled breath.
Study: NCT05520684

Intervention type: DIAGNOSTIC_TEST
Intervention: urine culture and urinalysis
Description: urine culture and urinalysis

Intervention type: DIAGNOSTIC_TEST
Intervention: urine culture and urinalysis
Description: urine culture and urinalysis
Study: NCT06022978

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Submucosal Saline Injection
Description: Inject 3-5 mL of saline into the submucosa within 10 minutes using a single-use 22G mucosal needle. The puncture point is located 0.5 cm from the edgeof the lesion, and the saline injection is stopped when the esophageal mucosa is elevated by approximately 1 cm.
Study: NCT06306001

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylene Blue
Description: Subjects in the intervention arm will receive a 1 mg/kg bolus of methylene blue over 30 minutes, followed by an infusion of 0.15 mg/kg/h. The infusion rate may be increased in steps of 0.15 mg/kg/h every 30 minutes until a maximum of 0.5 mg/kg/h.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects in the placebo arm will receive normal saline in the same volumetric dose as methylene blue in the intervention arm
Study: NCT06458569

Intervention type: OTHER
Intervention: Rehabilitation
Description: 3-weeks rehabilitation in hospital
Study: NCT05863455

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mild sedation and analgesia
Description: Intravenous injection of 0.1ug/kg sufentanil and 0.03mg/kg midazolam for sedation and analgesia before radial artery cannulation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: ntravenous injection of an equivalent volume of saline before radial artery cannulation.
Study: NCT05384314

Intervention type: DEVICE
Intervention: RespiraSense
Description: The use of continuous electronic monitoring of respiratory rate

Intervention type: DEVICE
Intervention: RespiraSense
Description: The use of continuous electronic monitoring of respiratory rate
Study: NCT04670861

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Upper extremity Biodex balance training
Description: The person assumes the prone plank posture with both hands poisoned in the area assigned for foot placement on the tilting balance platform. Using the four keypads, the person's left hand, left wrist, right hand and right wrist positions are entered into the system using the midline of the hand and the platform grid as reference points. The dot that appears on the position patient screen represents the person's segmental center of gravity.~During each trial test, the person should shift his weight to move the cursor from the center along a target path and back as quickly and with a little deviation as possible. The same process is repeated for each of the targets. Target paths activate in a random order.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Upper extremity Biodex balance training
Description: The person assumes the prone plank posture with both hands poisoned in the area assigned for foot placement on the tilting balance platform. Using the four keypads, the person's left hand, left wrist, right hand and right wrist positions are entered into the system using the midline of the hand and the platform grid as reference points. The dot that appears on the position patient screen represents the person's segmental center of gravity.~During each trial test, the person should shift his weight to move the cursor from the center along a target path and back as quickly and with a little deviation as possible. The same process is repeated for each of the targets. Target paths activate in a random order.
Study: NCT05788445

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: nrTMS treatment
Description: Using the nrTMS treatment coli to stimulation with high frequency

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: nrTMS sham
Description: Using the nrTMS sham coli to stimulation with high frequency
Study: NCT05835648

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutrasumma
Description: On the basis of daily diet, dietary fiber supplement (Nutrasumma) was given once a day, 1 strip each time, before meals, and the intervention lasted for 3 months.
Study: NCT05878158

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Simvastatin
Description: pulpotomy of immature permanent teeth

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Simvastatin
Description: pulpotomy of immature permanent teeth
Study: NCT05303415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromodulation with low-intensity focused ultrasound
Description: Application of LIFU to induce temporary neuromodulation, effects tested with resting state and heat evoked (QST) fMRI signals
Study: NCT05591144

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone tablet
Description: The dose selection of oral prednisone is the maximum daily dose based on weight for 4 days, followed by a taper every 2 days, with the maximum duration to 14 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ginkgo Biloba Extract
Description: Ginkgo biloba extracts are traditional Chinese medicine, which can improve microcirculation and provide good ameliorating effects for the treatment of tinnitus

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ginkgo Biloba Extract
Description: Ginkgo biloba extracts are traditional Chinese medicine, which can improve microcirculation and provide good ameliorating effects for the treatment of tinnitus
Study: NCT05317611

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intraperitoneal instillation of ondansetron and bupivacaine
Description: The aim is to detect the effect of intraperitoneal instillation of ondansetron for prevention of postoperative nausea and vomiting

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous ondansetron and intraperitoneal instillation of bupivacaine
Description: The aim is to detect effect of intravenous ondansetron for prevention of postoperative nausea and vomiting

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Intraperitoneal instillation of bupivacaine
Description: The aim is to detect effect of intraperitoneal instillation of bupivacaine
Study: NCT05520086

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single Dose
Description: Single Dose: Administration of 12,5 million allogeneic mesenchymal stem cells derived from adipose tissue by subcnjunctival injection and topical conjunctival injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Double Dose
Description: Repetead Dose: Administration of 2 doses, separated by 14 days, of 12,5 million allogeneic mesenchymal stem cells derived from adipose tissue by subcnjunctival injection and topical conjunctival injection.
Study: NCT06306313

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ReoGo
Description: ReoGo is a fixed arm rehabilitation exoskeleton that comes on a small and compact wheeled platform. The end-effector extension is capable of producing a wide range or repeatable movements in 3D space. ReoGo can be used by both adults and children. It is an arm rehabilitation exoskeleton with a fixed base. Its design allows limited controlled movements of the shoulder as well as the elbow and wrist.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physiotherapy
Description: Physiotherapy protocols will be created with traditional physiotherapy practices such as neurodevelopmental techniques based on muscle strengthening and task-oriented exercises. Protocols in general terms; It will include passive and active joint range of motion exercises, stretching exercises, stimulation and facilitation techniques, strengthening exercises, fine motor skills and functional task training for daily living activities. Protocols will be tailored to each patient's level of motor impairment and functional needs.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physiotherapy
Description: Physiotherapy protocols will be created with traditional physiotherapy practices such as neurodevelopmental techniques based on muscle strengthening and task-oriented exercises. Protocols in general terms; It will include passive and active joint range of motion exercises, stretching exercises, stimulation and facilitation techniques, strengthening exercises, fine motor skills and functional task training for daily living activities. Protocols will be tailored to each patient's level of motor impairment and functional needs.
Study: NCT06307548

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aminolevulinic Acid
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study: NCT06022978

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Submucosal Saline Injection
Description: Inject 3-5 mL of saline into the submucosa within 10 minutes using a single-use 22G mucosal needle. The puncture point is located 0.5 cm from the edgeof the lesion, and the saline injection is stopped when the esophageal mucosa is elevated by approximately 1 cm.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blue laser Imaging and Magnifying Endoscopy
Description: It is a new system for image-enhanced endoscopy using laser light. By clicking a button on the endoscope only , endoscopists can electronically stain and magnify the digestive tract lesions. This system can help endoscopists observe leisons more clearly and improve diagnosic accuracy.
Study: NCT04784156

Intervention type: PROCEDURE
Intervention: Subtalar (Talocalcaneal) Arthrodesis
Description: Subtalar (Talocalcaneal) arthrodesis with a novel sustained dynamic compression intramedullary nail
Study: NCT06307548

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fluorescence-Guided Surgery
Description: Undergo fluorescence-guided surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Photodynamic Therapy
Description: Undergo PDT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Procedure
Description: Undergo surgery
Study: NCT04691635

Intervention type: OTHER
Intervention: evaluation of movements with sensors
Description: evaluation of movements with sensors

Intervention type: OTHER
Intervention: evaluation of movements with sensors
Description: evaluation of movements with sensors

Intervention type: OTHER
Intervention: evaluation of movements with sensors
Description: evaluation of movements with sensors
Study: NCT04784156

Intervention type: DEVICE
Intervention: DynaNail Mini
Description: Utilization of a novel sustained dynamic compression pseudoelastic intramedullary nail
Study: NCT05313581

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: START NOW WebApp
Description: The WebApp is based on the existing manualized START NOW skills training. START NOW aims to improve emotion- and stress regulation, social competence, effective management of encountered problems/crises, subjective well-being and resilience through improving an individual's level of psychological flexibility. It primarily employs a cognitive behaviourally oriented group skills training with integrated components from Dialectical Behavioural Therapy (DBT), Acceptance and Commitment Therapy (ACT), trauma-informed care and Motivational Interview (MI) techniques.~During the training, participants will encounter different exercises to help them train their skills. There are several mindfulness exercises in the form of audio tracks, containing, e.g., instructions on a breathing exercise. The skills training phase takes place over a period of 9 weeks (sessions 1+2, 9+10 and 11+12 are double session).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: START NOW WebApp
Description: The WebApp is based on the existing manualized START NOW skills training. START NOW aims to improve emotion- and stress regulation, social competence, effective management of encountered problems/crises, subjective well-being and resilience through improving an individual's level of psychological flexibility. It primarily employs a cognitive behaviourally oriented group skills training with integrated components from Dialectical Behavioural Therapy (DBT), Acceptance and Commitment Therapy (ACT), trauma-informed care and Motivational Interview (MI) techniques.~During the training, participants will encounter different exercises to help them train their skills. There are several mindfulness exercises in the form of audio tracks, containing, e.g., instructions on a breathing exercise. The skills training phase takes place over a period of 9 weeks (sessions 1+2, 9+10 and 11+12 are double session).
Study: NCT06027138

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: blood flow resistance training
Description: Muscle size and explosive power was determined by measuring the diameter of its arm and thigh muscles and performing 1RM testing in barbell parallel back squats and foot barbell Bench press ,vertical jump test and timed push ups and pull up tests .secondly treat the arm and thigh muscles to to blood flow resistance training and is administered for approx 2 months a frequency of four times per week at an intensity of seventy five to eight five percent for 4 to 12 reps,1 to 5 sets, at interval of 30 to 40 sec.then determine the impact of treatmnt measurement was again carried out on the circumference and explosive strength of arm and thigh muscles.
Study: NCT04885959

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Traditional Asian Diet
Description: The personalized traditional Asian diet will be formulated based on dietary components of a typical Asian diet characterized by high intake of fruits and vegetables, whole grains, legumes, nuts, seeds, soy foods and herbs and spices; moderate intake of fish, poultry, eggs, healthy cooking oils, yogurt or functional foods and low intake of meats and sweets (Ismail et al., 2020). The diet design also considering the recommendation of personalized dietary approach by including the element of individual preferences, requirement, cultural preferences, affordability and foods availability to facilitate the adherence and response to the diet.
Study: NCT04862754

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: interval training exercise
Description: interval training exercise
Study: NCT06156150

Intervention type: BIOLOGICAL
Intervention: tumor vaccine
Description: DC vaccine produced by the Team