TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05894291

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swimmer Prone Position
Description: Patients will be positioned with the head rotated. This rotation is followed by shoulder elevation/abduction, then 90° elbow flexion for the arm opposite to the head rotation. The hand is placed flat on the bed.~A 60° to 90° flexion is performed on the hip homolateral to head rotation, combined with knee flexion.~The position is changed to the mirror position every 4 hours.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Prone position with arms alongside the body
Description: The head will be positioned either straight or rotated to one side, depending on ICU habits. The arms are positioned symmetrically along the body, palms up. The lower limbs are positioned symmetrically and parallel, knees extended or slightly flexed if a cushion is used on the front of the feet.~Head rotation, if applicable, is performed every 4 hours.
Study: NCT06604754

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Assigned Intervention for VR Training
Description: In VR training patients use VR headsets to engage in virtual environments for 8 weeks where they perform exercises designed to enhance balance, coordination, and strength. Simultaneously, the VR platform incorporate pulmonary exercises that focus on improving breathing techniques, lung capacity, and overall respiratory health. Patients will engage in 3 sessions per week with total time duration of 45 to 60 minutes. VR-based training provides real-time feedback and adapts to the patient's progress, offering a comprehensive approach to rehabilitation that addresses both balance and pulmonary function in a motivating and controlled manner.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Assigned Intervention for Traditional Physical Therapy Training
Description: In Traditional physical therapy balance training for patients with chronic obstructive pulmonary disease (COPD) involves exercises designed to improve stability, strength, and coordination for duration of 8 weeks. These exercises, such as static balance tasks, dynamic movement drills, and strength training, help address the balance deficits often seen in COPD patients due to muscle weakness and reduced physical activity. Additionally, pulmonary effects are managed through breathing exercises such as deep breathing and pursed lip breathing that enhance respiratory functions, improve lung capacity and efficiency.
Study: NCT05027412

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: En bloc TURBT Collins Loop
Description: En bloc TURBT Collins Loop
Study: NCT05557695

Intervention type: DRUG
Intervention: Acalabrutinib
Description: Acalabrutinib
Study: NCT05952401

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Usual care will be informed by practice guidelines (patient smoking cessation handout and brief advice).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nudges
Description: Patients in the experimental arm will receive practice guidelines (patient smoking cessation handout and brief advice) and Nudges to Quit, guideline-informed messages immediately following patient tobacco treatment needs assessment.
Study: NCT06507150

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AI-assisted migraine education (AIME)
Description: AIME Group will undergo the established migraine education plus AI-assisted education.
Study: NCT05027412

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional TURBT
Description: Conventional TURBT
Study: NCT04557566

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: EBT yoga-based eating disorder course
Description: Yoga for Eating Disorder Recovery online course. This course will be led by certified facilitators via Zoom and offered over the course of four weeks, comprising one two-hour session per week. The course will continue to recruit and enroll participants until sufficient power is reached for the study.
Study: NCT06236204

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthroscopic Scapholunate Ligament Reconstruction
Description: reconstruction of the SL ligament with palmaris tendon graft tunneled through the scaphoid and lunate as described by Corella et al.
Study: NCT05546931

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coaching application
Description: A digital application for providing education and support for home-based blood pressure monitoring.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: WebMD
Description: Smartphone-based application for health education and/or monitoring.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Home-based blood pressure monitoring
Description: Device for measuring blood pressure at home with blue tooth connectivity for automated collection.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based blood pressure monitoring
Description: Device for measuring blood pressure at home with blue tooth connectivity for automated collection.
Study: NCT05037513

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SBCM-PrEP
Description: Multi-session SBCM intervention adapted for PrEP initiation focus

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CDC-PrEP
Description: 1 session PrEP education following CDC guidelines
Study: NCT05245877

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: enoxaparin/tinzaparin/dalteparin
Description: Patients randomized to the preoperative thromboprophylaxis will have their thromboprophylaxis initiated approximately 2-14 hours prior to the planned pancreatic surgery skin incision (depending on the center's current practice and logistics). Thromboprophylaxis can be initiated using enoxaparin (20 - 40 mg), tinzaparin (2500 - 4500 IU), or dalteparin (2500 - 5000 IU), with the dose based on patient's renal function according to the local standard of care. A center may reduce the dose 25-50% if the dose is given very close to the skin incision (i.e. at the morning of the operation instead of the evening before the operation).
Study: NCT04842305

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood- and saliva tests
Description: Measurement of SARS-CoV-2 spike glycoprotein RBD antibodies in plasma and saliva

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood- and saliva tests
Description: Measurement of SARS-CoV-2 spike glycoprotein RBD antibodies in plasma and saliva

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood- and saliva tests
Description: Measurement of SARS-CoV-2 spike glycoprotein RBD antibodies in plasma and saliva

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood- and saliva tests
Description: Measurement of SARS-CoV-2 spike glycoprotein RBD antibodies in plasma and saliva
Study: NCT06334874

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Astaxanthin Oral Capsule
Description: 12 mg of astaxanthin oral capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: starch placebo capsule
Study: NCT05941260

Intervention type: DIAGNOSTIC_TEST
Intervention: Computational fluid dynamics (CFD)
Description: - Video recording starts in an antegrade manner starting from the bladder neck through the prostatic urethra and ends after the verumontanum at the external sphincter. Videos were taken with a very slow movement of the endoscope to ensure the sharpness of the data and to prevent complications in post-processing.~The focal length and zoom of the endoscope camera were set at the beginning and maintained throughout the capturing, while the angle of the lens changes to capture the widest field possible for each targeted area.~* Computational fluid dynamics (CFD) can then be used to numerically model the behavior of the flow inside the urethra by solving the governing equations of the flow using the finite volume method.~* Through which we can develop a urodynamic computer model to simulate the bladder-urethral passage and predict the success of the resection undertaken by the surgeon. No extra intervention will be provided to our patients apart from their routine surgery.
Study: NCT04937296

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will be asked to perform resistance exercises 3-times a week on alternating days for 12 weeks. Exercises will be performed with a TheraBand and will include the squat, lunge, press-up, cross body reach, reverse fly, lateral raise, biceps curl, triceps extension, frontal raise and bridge. In addition to the resistance exercises, the participants will perform aerobic exercise. They will be asked to download a specific exercise app to record the number of steps on day 1 of the intervention and participants who do not possess the required phone technology will be provided with a pedometer. They then will be asked to add 2000 steps on to their daily steps; this amount will then become their daily step goal. Once they have reached this goal on 4 out of 5 days, they will be asked to increase their new step step goal by an extra 500 per day.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Usual care
Description: Usual care.
Study: NCT06018714

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Drug:~Maintenance treatment regimen:~Fruquintinib 5 mg, qd, po, with three weeks of continuous treatment followed by one week of drug discontinuation. Each treatment cycle lasts four weeks. The treatment will be continued for six months, or until tumor recurrence, metastasis, or intolerable drug toxicities occur within six months.~Adverse drug reactions that occur during the trial will be graded according to the NCI CTCAE version 5.0 and dose adjustments will be made according to the corresponding rules.
Study: NCT06406192

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Height, Weight, and Blood Pressure Measurement Procedures Improvement
Description: In the intervention group, the investigators improve the process of measuring blood pressure, height, and weight, requiring timely recording of these measurements. The intervention includes:~i. Enlisting the assistance of nurses and volunteers to improve the accessibility of measurement environments and provide guidance on instrument operation.~ii. Using paper reminders at check-in stations to prompt patients to complete blood pressure and weight recordings before entering examination rooms; providing paper for recording if patients forget their health insurance cards.~iii. Providing alcohol and hand wipes outside examination rooms for disinfecting measurement instruments.~iv. Promoting the recording mode outside the check-in station.~v. Ensuring that physicians or nurses in examination rooms accurately record measurements in the medical order system.~vi. Encouraging patients to ask physicians during consultations, Is my blood pressure and weight okay?
Study: NCT05407415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kardia Mobile 6L Device
Description: The KardiaAL is a software analysis library intended to assess ambulatory electrocardiogram (ECG) rhythms from adult subjects. The device supports analyzing data recorded in compatible fonnats from any ambulatory ECG devices such as event recorders, or other similar devices. The library is intended to be integrated into other device software. The library is not intended for use in life supporting, or sustaining systems, or ECG monitors, or cardiac alarm, or OTC use only devices.~The KardiaAI library provides the following capabilities:~* ECG noise filtering,~* heart rate measurement from ECGs,~* detection of noisy ECGs, and~* ECG rhythm analysis for detecting the presence of normal sinus rhythm, atrial fibrillation, bradycardia, and tachycardia (when prescribed or used under the care of a physician).
Study: NCT04190524

Intervention type: OTHER
Group type: OTHER
Intervention: Application of cricoid pressure
Description: The study first involves recording a baseline image of the neck anatomy using ultrasound, which is a non-invasive, non-irradiating, non-painful imaging modality. Once the baseline anatomy has been imaged, conventional cricoid pressure will be applied with fingers and/or with the ultrasound probe itself and an image will be recorded. The force applied to the cricoid cartilage will be 30 newtons, as determined by a thin force measurement sensor (Tekscan flexiforce sensor) placed in between the patient's skin and the finger (or ultrasound probe).

Intervention type: OTHER
Group type: OTHER
Intervention: Application of Left lateral paratracheal pressure
Description: Next, left lateral paralaryngeal pressure will be applied at the level of the cricoid cartilage with fingers and/or the ultrasound probe itself, and the image will again be recorded. Left lateral paralaryngeal pressure will be 30 newtons, as determined by a thin force measurement sensor placed in between the patient's skin and the finger (or ultrasound probe).
Study: NCT05547789

Intervention type: DRUG
Intervention: non steroidal anti inflammatory drugs
Description: effect of non steroidal anti inflammatory drugs on macular changes
Study: NCT04891185

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine green
Description: Administration of the IMP: Indocyanine green, 0,25mg/kg of body weight, intravenous bolus injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine green
Description: Administration of the IMP: Indocyanine green, 0,25mg/kg of body weight, intravenous bolus injection
Study: NCT05701891

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Physiotherapy with integrated Virtual Reality
Description: A 12-week personalised, VR-integrated physiotherapy intervention.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy (usual care)
Description: A 12-week usual physiotherapy care intervention.
Study: NCT05910333

Intervention type: OTHER
Intervention: observation
Description: To compare the effect of the mandibular implant retained OVD using quadrilateral distribution (QD) versus linear distribution (LD) on posterior mandibular ridge resorption (PMandRR), anterior maxillary ridge resorption (AMaxRR), and changes to the crestal bone level around implants after 10 years of function.

Intervention type: OTHER
Intervention: observation
Description: To compare the effect of the mandibular implant retained OVD using quadrilateral distribution (QD) versus linear distribution (LD) on posterior mandibular ridge resorption (PMandRR), anterior maxillary ridge resorption (AMaxRR), and changes to the crestal bone level around implants after 10 years of function.
Study: NCT05322330

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: 40-60mg QW,w-3～d-3,PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Flu
Description: 25-30 mg/m2，d-5 ～d-3，qd，ivgtt

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTX
Description: 250-500 mg/m2，d-5 ～d-3，qd，ivgtt

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAR-T
Description: 2-5×10\^6 CAR-T/kg，ivgtt。
Study: NCT05340179

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Interlaminar cervical epidural injection
Description: Fluoroscopy-guided interlaminar cervical epidural injection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cervical selective nerve root block
Description: Ultrasound-guided cervical selective nerve root block
Study: NCT06152497

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: H1 blockade: Telfast: 180mg Fexofenadine
Description: H1 blockade: oral blockade with 180mg Fexofenadine

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Resistance training
Description: Resistance training: lower body exercise

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance training
Description: Resistance training: lower body exercise
Study: NCT04468191

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental expiratory muscle strength training (EMST)
Description: The experimental EMST will involve blowing into a device with a spring-loaded valve set to 50% of the patient with ALS' maximum expiratory pressure.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental expiratory muscle strength training (EMST)
Description: The experimental EMST will involve blowing into a device with a spring-loaded valve set to 50% of the patient with ALS' maximum expiratory pressure.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham expiratory muscle strength training (EMST)
Description: The sham EMST will involve blowing into a device without a spring-loaded valve (0% resistance).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham expiratory muscle strength training (EMST)
Description: The sham EMST will involve blowing into a device without a spring-loaded valve (0% resistance).
Study: NCT04828304

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PLASOMA
Description: Treatment with cold plasma device
Study: NCT05687214

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic manipulative treatment
Description: Each participant in the experimental group will receive eight osteopathic manipulative treatments. Each treatment will include the following manipulations:~* Pompage Cv4;~* Occipital-sternal technique;~* Relaxining manipulation of the diaphragmatic domes;~* Pelvic and abdominal diaphragm synchronization;~* Dynamogenic technique;~* Mesenteric traction;~* Release of colic angles;~* Manipulation and mobilization of the sacrum.
Study: NCT04772144

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: behavioural and cessation aids
Description: information, motivational interview, refferal to healty life-centers, free cessation aids
Study: NCT05976009

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active rTMS stimulating
Description: Two sessions of active rTMS would be delivered, with 1800 pulse/session and 50 min inter-session intervals.
Study: NCT05833451

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reiki
Description: Reiki, one of integrative practices, is an energy therapy involving the use of energy that flows naturally from the hands of the practitioner to strengthen the body's ability to heal itself in order to increase well-being. Reiki improves well-being in many areas, ensures that blood and lymph circulation is maintained properly, regulates blood pressure and pulse rate by stimulating the autonomic nervous system, increases comfort, reduces depression and anxiety levels. In this way, Reiki facilitates physical and mental relaxation and promotes health
Study: NCT06500546

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Treatment of cervical lesions
Description: Four non-carious cervical lesions from patients will be separated into four groups according to according to the adhesion trategies described below:~1. adhesive material will be applied in total-etch mode,~2. adhesive material will be applied in self-etch,~3. universal adhesive material will be applied for 10 sec. in total-etch mode, which includes rubbing,~4. universal adhesive material will be applied for 10 sec. in self-etch mode, which includes rubbing,

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Treatment of cervical lesions
Description: Four non-carious cervical lesions from patients will be separated into four groups according to according to the adhesion trategies described below:~1. adhesive material will be applied in total-etch mode,~2. adhesive material will be applied in self-etch,~3. universal adhesive material will be applied for 10 sec. in total-etch mode, which includes rubbing,~4. universal adhesive material will be applied for 10 sec. in self-etch mode, which includes rubbing,
Study: NCT05880329

Intervention type: DIAGNOSTIC_TEST
Intervention: Candidate POCTs for detecting UTI
Description: POCT performance will be evaluated in participants who experience possible UTI.
Study: NCT05608772

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: revision surgery
Description: revision procedure after failed sleeve gastrectomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: revision surgery
Description: revision procedure after failed sleeve gastrectomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: revision surgery
Description: revision procedure after failed sleeve gastrectomy
Study: NCT06477432

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mesofiller® mesotox
Description: The investigated product mesofiller® mesotox was applied by intradermal or subcutaneous injection by the investigator during Session 1 for all subjects and Session 2 for the subjects, for whom a touch-up was considered beneficial. Both sessions were conducted within 14-day intervals.
Study: NCT06477523

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Etoposide intravenous infusion was administered at a dose of 100 mg/m\^2 on Days 1, 2, and 3 of each 21-day cycle during the induction phase (Cycles 1-4).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin intravenous infusion to achieve an initial target AUC of 5 mg/mL/min was administered on Day 1 of each 21-day cycle during the induction phase (Cycles 1-4).

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: low-dose radiotherapy
Description: The subjects will receive LDRT, from C1D1-C1D5, once a day for 3Gy, until the target dose of 15Gy is achieved (Cycles 1).~LDRT treatment for primary/mediastinal positive lymph nodes/metastatic lesions during maintenance therapy (C1D1-C1D5, 15Gy).
Study: NCT05224856

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CT-P63 and CT-P66 / Placebo
Description: Inhalation

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: CT-P63 and CT-P66 / Placebo
Description: Inhalation
Study: NCT04938453

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nintedanib 25 mg
Description: soft gelatin capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nintedanib 25 mg
Description: soft gelatin capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nintedanib 100 mg
Description: soft gelatin capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nintedanib 100 mg
Description: soft gelatin capsule
Study: NCT05866432

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Datopotamab deruxtecan
Description: Will be given until PD or withdraw
Study: NCT06169566

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: synbiotics
Description: synbiotics

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo
Study: NCT05299112

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Arginine
Description: The intervention parenteral nutrition contains additional arginine (18% arginine content) as compared to standard parenteral nutrition (6.3% arginine content).
Study: NCT04473989

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: recombinant teriparatide for injection
Description: weekly subcutaneous administration of 40 ug

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: weekly subcutaneous administration of 40 ug