TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04830878

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Systemic and intraoperative intravitreal injection of methotrexate
Study: NCT04103502

Intervention type: DEVICE
Intervention: MicroPort Medial Pivot TKA
Description: Subjects will have been implanted with the MicroPort Medial Pivot TKA

Intervention type: DEVICE
Intervention: DePuy Attune PCR TKA
Description: Subjects will have been implanted with the DePuy Attune PCR TKA
Study: NCT05865925

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY010616
Description: IV infusion was 90min (±5min), with an interval of 3 weeks between the first administration and the second administration, and once every 2 weeks thereafter

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY010616
Description: IV infusion was 90min (±5min), with an interval of 3 weeks between the first administration and the second administration, and once every 2 weeks thereafter

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY010616
Description: IV infusion was 90min (±5min), with an interval of 3 weeks between the first administration and the second administration, and once every 2 weeks thereafter

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY010616
Description: IV infusion was 90min (±5min), with an interval of 3 weeks between the first administration and the second administration, and once every 2 weeks thereafter

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY010616
Description: IV infusion was 90min (±5min), with an interval of 3 weeks between the first administration and the second administration, and once every 2 weeks thereafter

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY010616
Description: IV infusion was 90min (±5min), with an interval of 3 weeks between the first administration and the second administration, and once every 2 weeks thereafter
Study: NCT06097273

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1083
Description: Suspension for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride suspension for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride suspension for injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Influenza Vaccine
Description: Commercially available formulation (Suspension for injection \[pre-filled syringe\])

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Influenza Vaccine
Description: Commercially available formulation (Suspension for injection \[pre-filled syringe\])

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 Vaccine
Description: Commercially available formulation (Suspension for injection)

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 Vaccine
Description: Commercially available formulation (Suspension for injection)
Study: NCT06230952

Intervention type: OTHER
Intervention: BASDAI and BASFI reliability
Description: The study will be carried out on volunteer patients who are diagnosed with axial spondyloarthritis and are followed up in the outpatient clinic of Dokuz Eylül University, Department of Internal Medicine, Rheumatology and Immunology Department, and who meet the inclusion criteria. Patients who volunteer to participate in the study will be contacted by phone and BASDAI and BASFI questionaires will be administered.
Study: NCT05963451

Intervention type: OTHER
Intervention: No intervention
Description: No intervention will be given in our study since, the investigators are recruiting people who will receive already a facet thermal ablation.
Study: NCT06264037

Intervention type: OTHER
Intervention: semi structured interview
Description: semistructured interview on patient\&#39;s experience of hospitalization.

Intervention type: OTHER
Intervention: semi structured interview
Description: semistructured interview on patient\&#39;s experience of hospitalization.

Intervention type: OTHER
Intervention: semi structured interview
Description: semistructured interview on patient\&#39;s experience of hospitalization.

Intervention type: OTHER
Intervention: semi structured interview
Description: semistructured interview on patient\&#39;s experience of hospitalization.
Study: NCT04934982

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Total Laparoscopic or Robotic Radical Hysterectomy
Description: Stage IA1 with lymphovascular interstitial infiltration and IA2 surgical approach was type B (modified radical hysterectomy plus bilateral pelvic lymph node dissection, i.e., resection of 1\~2 cm of the parametrium and 1\~2 cm of the vagina) with abdominal para-aortic lymph node dissection if necessary (surgical staging according to FIGO 2018 and surgical staging according to Querleu-Morrow staging).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Total Abdominal Radical Hysterectomy
Description: Stage IA1 with lymphovascular interstitial infiltration and IA2 surgical approach was type B (modified radical hysterectomy plus bilateral pelvic lymph node dissection, i.e., resection of 1\~2 cm of the parametrium and 1\~2 cm of the vagina) with abdominal para-aortic lymph node dissection if necessary (surgical staging according to FIGO 2018 and surgical staging according to Querleu-Morrow staging).
Study: NCT04760223

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video intervention
Description: a 100-second video, presenting a personal story of a boy/girl dealing with depression

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video intervention
Description: a 100-second video, presenting a personal story of a boy/girl dealing with depression

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Video intervention
Description: a 100-second video, presenting a personal story of a boy/girl dealing with depression

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Video intervention
Description: a 100-second video, presenting a personal story of a boy/girl dealing with depression
Study: NCT05869656

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fluid restriction
Description: Oral fluid restriction of 1000ml per day

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Free fluids
Description: Continue care without any oral fluid restriction
Study: NCT06252090

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Short term mentalization-based treatment for adolescents (MBT-A)
Description: The general framework of intervention corresponds to the Mentalization-Based Treatment model for adolescents (MBT-A). In this study, the model was adapted to a brief, time-limited format (12 sessions) aimed at both the adolescent and their family. The model retains the main characteristics of Mentalization-Based Therapy, such as the therapist's basic attitude toward actively promoting patients' mentalization, uncertainty of mental states, focus on the here and now, and the use of affect as a mechanism for change.
Study: NCT06187272

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Listening to music
Description: Students listened to background music during a practical examination of 60 bpm.
Study: NCT04896684

Intervention type: BIOLOGICAL
Intervention: blood and intestinal biopsy sampling
Description: 24 mL of blood and 10 intestinal biopsies will be sampled
Study: NCT06342245

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiofrequency coblation micro-tenotomy
Description: Radiofrequency micro-tenotomy with low-temperature controlled ablation will be performed with the TOPAZ (Smith and Nephew) wand, which has a 1mm tip, and full thickness 1mm RF tendon debridement at 5mm intervals will be performed.
Study: NCT05768737

Intervention type: OTHER
Intervention: Patient Participation Form
Description: A form that consists of revised osteoporosis knowledge test, osteoporosis self-efficacy scale, and osteoporosis health belief scale.
Study: NCT05745181

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-T Cell Infusion
Description: Peripheral blood mononuclear cells were isolated, amplified and cultured in vitro, pretreated with FC regimen, and Anti-CD1a CAR-T cells were transfused.
Study: NCT05404217

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: LN-OS-22
Description: 2 capsules orally once a day to be taken with a glass of milk after breakfast for 56 days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: 2 capsules orally once a day to be taken with a glass of milk after breakfast for 56 days
Study: NCT05089981

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: N acetyl cysteine
Description: Intravenous use of N acetyl cysteine in prescribed doses

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of N acetyl cysteine
Description: Intravenous Placebo of N Acetyl cysteine in look alike form (Normal saline)
Study: NCT05135793

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topoprazan
Description: 1 tablet contains 20 mg vonoprazan

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Takecab
Description: 1 tablet contains 20 mg vonoprazan
Study: NCT05588947

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Take Charge session
Description: A 'talk therapy' session designed to harness the person's self-determination, re-establishing purpose, identity, autonomy, and skills to Take Charge of their recovery after stroke

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Control
Description: Life After Stroke educational video
Study: NCT05571423

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Medical Play
Description: Study subject will be engage in the medical play.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Routine Play
Description: Study subject will be engage in the routine play (coloring exercise).
Study: NCT04765553

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NI-0501
Description: emapalumab single i.v infusion (1 mg/kg)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline single i.v infusion
Study: NCT04383847

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sumadhur Aarambha
Description: Group intervention for newly married women, their husbands, and mothers-in-law with information mainly about nutrition, but also pre-pregnancy health, reproductive/pregnancy health and gender equality.
Study: NCT05220956

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Intermittent fasting
Description: One arm will undergo a TRF diet (Time-Restricted Feeding) for 12 weeks while both arms undergo a training according to the 10 rules of healthy nutrition of the DGE.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: DGE diet
Description: The control arm is not a subject to any time restrictions concerning eating while both arms undergo a training according to the 10 rules of healthy nutrition of the DGE.
Study: NCT06105762

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ketogenic Diet
Description: The ketogenic diet intervention, administered as a Modified Atkins Diet, involves a significantly reduced daily carbohydrate intake, typically less than 20 grams of net carbs. This approach primarily relies on higher fat consumption to induce ketosis, a metabolic state characterized by elevated ketone body production, serving as an alternative brain fuel source.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic Diet
Description: The ketogenic diet intervention, administered as a Modified Atkins Diet, involves a significantly reduced daily carbohydrate intake, typically less than 20 grams of net carbs. This approach primarily relies on higher fat consumption to induce ketosis, a metabolic state characterized by elevated ketone body production, serving as an alternative brain fuel source.
Study: NCT06465992

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exparel 266 MG Per 20 ML Injection
Description: 20 mL Liposomal bupivacaine (Exparel, 266 mg) will be administered in the popliteal and saphenous block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exparel 266 MG Per 20 ML Injection
Description: 20 mL Liposomal bupivacaine (Exparel, 266 mg) will be administered in the popliteal and saphenous block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hcl 0.75% Inj
Description: 10 mL of 0.75% bupivacaine will be administered in popliteal and saphenous block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hcl 0.75% Inj
Description: 10 mL of 0.75% bupivacaine will be administered in popliteal and saphenous block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: 1 mL of 10 mg Dexamethasone will be administered in the popliteal and saphenous block
Study: NCT05390996

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: dental implant placement
Description: dental implant placement by using a different drilling techniques

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: dental implant placement
Description: dental implant placement by using a different drilling techniques
Study: NCT05277506

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 18 inch slot MBT orthodontic brackets bonded using smile arc protection bonding strategy
Description: female patients with mild crowding will recieve orthodontic brackets bonding using smile arc protection bonding strategy

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 18 inch slot MBT orthodontic brackets boned using MBT placement guide
Description: female patients with mild crowding will recieve orthodontic brackets bonding using MBT placement guide bonding strategy
Study: NCT05238155

Intervention type: DRUG
Intervention: antimetabolite
Description: When OLT recipients are discharged following transplantation, they are typically prescribed a triple immunosuppression maintenance regimen, consisting of a calcineurin inhibitor, an antimetabolite, and a corticosteroid. Over the last several years, there have been changes made to this protocol, and the current protocol now suggests
Study: NCT05971472

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Arthroscopic Repair
Description: Arthroscopic Repair for medial meniscus posterior Root tears

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High tibial osteotomy
Description: Open Wedge High tibial osteotomy for medial meniscus posterior Root tears
Study: NCT05804461

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Upon refinement from Formative Research (Aim 1), a three-session, individual-level intervention to increase Pre-Exposure Prophylaxis (PrEP) uptake among men who have sex with men (MSM) in Puerto Rico will be implemented. The facilitator will use Motivational Interviewing techniques to guide the sessions. The intervention's design and content will be the same for each study group; the only difference will be the modality of implementation; one group of participants will receive a face-to-face intervention, while another group will receive an online intervention.A total of 170 participants will be randomized in a 1:1 ratio into each of the two intervention modalities (n=85 face-to-face and n=85 online) while a control group will be recruited following a 3:1 ratio of intervention vs. control. In addition to baseline assessment, participants will be asked to complete a post test at the end of the third session (60 days) and a follow-up post-test at the 150-day mark, separately.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Upon refinement from Formative Research (Aim 1), a three-session, individual-level intervention to increase Pre-Exposure Prophylaxis (PrEP) uptake among men who have sex with men (MSM) in Puerto Rico will be implemented. The facilitator will use Motivational Interviewing techniques to guide the sessions. The intervention's design and content will be the same for each study group; the only difference will be the modality of implementation; one group of participants will receive a face-to-face intervention, while another group will receive an online intervention.A total of 170 participants will be randomized in a 1:1 ratio into each of the two intervention modalities (n=85 face-to-face and n=85 online) while a control group will be recruited following a 3:1 ratio of intervention vs. control. In addition to baseline assessment, participants will be asked to complete a post test at the end of the third session (60 days) and a follow-up post-test at the 150-day mark, separately.
Study: NCT05836675

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intradialytic exercise
Description: The exercise program will be carried out during dialysis time. Participants will be asked to carry out cycling for 15-20 minutes, resistance exercises, and Kegel exercises during the first 2 hours of their regular routine hemodialysis session. Exercise can be done with rest periods as necessary.
Study: NCT04166110

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Predetermined treatment duration
Description: Antibiotic treatment duration left to the physician's judgement (following national guidelines, 7 to 14 days)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Variable treatment duration
Description: Treatment duration vary according to stability criteria reaching time Patients will self-monitor 2 times a day (in the morning and in the evening) using a set of connected devices, to monitor their vital signs before any treatment intake.~After at least 3 days of treatment and stability criteria obtained for the last 24 hours (i.e. 3 vital signs recording), patients will stop the antibiotic treatment.
Study: NCT04634370

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Natural Killer Cells infusion
Description: Each patient will receive on dose of intravenous natural killer cell in following levels:~Level 1 : 1x106 cells/kg body weight (patients 1 to 3) Level 2: 5x106 cells/kg body weight (patients 4 to 6) Level 3: 1x107 cells/kg body weight (patients 7 to 24)
Study: NCT06018688

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib
Description: Osimertinib is a 3rd-generation EGFR-TKI used to treat NSCLC patients with resistance to 1st generation EGFR-TKI due to T790M mutation. It has been approved in clinical applications by the FDA in 2015.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin
Description: Aspirin, also known as acetylsalicylic acid (ASA), is a verysafe medication used to treat pain,fever, or inflammation.
Study: NCT05507398

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo, metformin and atorvastatin
Description: comparing the anti-tumor effects of metformin and atorvastatin

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo, metformin and atorvastatin
Description: comparing the anti-tumor effects of metformin and atorvastatin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo, metformin and atorvastatin
Description: comparing the anti-tumor effects of metformin and atorvastatin
Study: NCT05203809

Intervention type: DEVICE
Intervention: TempTraq temperature monitor
Description: All participants will wear both TempTraq temperature monitor and CORE temperature monitor.
Study: NCT04713176

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWJ1248 with Remdesivir
Description: 1 tablet of DWJ1248 TID(up to 14 days) PO, Remdesivir(up to 5 or 10 days) IV

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo with Remdesivir
Description: 1 tablet of placebo TID(up to 14 days) PO, Remdesivir(up to 5 or 10 days) IV
Study: NCT05471804

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Sceletium tortuosum
Description: Zembrin® is a proprietary low-alkaloid extract of Sceletium tortuosum, often consumed by healthy humans in order to decrease anxiety and stress and improve cognitive function under stressful situations

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Sceletium tortuosum
Description: Zembrin® is a proprietary low-alkaloid extract of Sceletium tortuosum, often consumed by healthy humans in order to decrease anxiety and stress and improve cognitive function under stressful situations
Study: NCT04843384

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reiki
Description: Reiki was performed according to the need of each patient and lasted an average of 20-25 minutes. After the procedure, the patients were left to rest for ten minutes. The researcher was focused in a neutral way on the sessions without the intention of healing. After the session, the patients were allowed to rest for ten minutes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham reiki
Description: With the Sham Reiki patients, a nurse without reiki training performed Sham Reiki randomly for approximately 20-25 minutes, following a protocol which did not include the body's energy centers or chakras.
Study: NCT05479188

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cerebral oximetry
Description: Cerebral oximetry monitoring with near-infrared spectroscopy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cerebral oximetry
Description: Cerebral oximetry monitoring with near-infrared spectroscopy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Peripheral oximetry
Description: Tissue perfusion monitoring with somatic near-infrared spectroscopy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Peripheral oximetry
Description: Tissue perfusion monitoring with somatic near-infrared spectroscopy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cerebral autoregulation
Description: Cerebral autoregulation monitoring with COx.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cerebral autoregulation
Description: Cerebral autoregulation monitoring with COx.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sublingual microscopy
Description: Evaluation of microcirculation with sublingual microscopy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sublingual microscopy
Description: Evaluation of microcirculation with sublingual microscopy.
Study: NCT04841070

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ages & Stages Questionnaires®, Third Edition (ASQ3)
Description: Investigators will propose to parents of children hospitalized for the treatment of persistent pulmonary hypertension of the newborn a hetero-evaluation via the validated ASQ questionnaire to analyze neuro-psychomotor development.