TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06136702

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-sampling
Description: Women will receive information about self-sampling and will be instructed by the community-based researcher on how to take a self-sample using an illustrative cartoon. Women will then be invited to take a sample on-site, to measure the uptake of the self-sampling test (% of women who take the self-sample). Furthermore, two self-administrated questionnaires are applied to 1) assess attitudes regarding self-sampling (pre-intervention), and 2) assess users' experience regarding self-sampling (post-intervention). The researcher will collect all samples for analysis by an HPV test in a lab. Sample analysis is expected to take 2 weeks time. All women will be contacted 1-2 weeks after the self-sample taking to inform them on their test result.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Follow-up assessment
Description: To gauge the knowledge on cervical cancer screening after the educational session and to verify whether they got a pap smear, a 3-month follow-up is proposed for all women receiving an educational session (arm 1) and all women receiving an educational session and a self-sample (arm 2), because all women, whether or not invited for self-sampling, are provided information on where to get screened, although there is no formal referral to screening services.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Follow-up assessment
Description: To gauge the knowledge on cervical cancer screening after the educational session and to verify whether they got a pap smear, a 3-month follow-up is proposed for all women receiving an educational session (arm 1) and all women receiving an educational session and a self-sample (arm 2), because all women, whether or not invited for self-sampling, are provided information on where to get screened, although there is no formal referral to screening services.
Study: NCT05748977

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SABA SAMA ICS Vs LABA LAMA ICs
Description: Short acting agents,long acting agents ,ics
Study: NCT04739800

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood
Study: NCT05240781

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Zotarolimus eluting stent
Description: Size (diameter and length) will be chosen at operator's discretion aided by simple angiography, QCA, or intravascular image; so that the lesion previously prepared and 2 mm at each end are covered by DES with an stent to artery ratio of 1.1. Post-dilatation will be performed when indicated. Device will be used by CE mark instructions.~All patients will receive DAPT as follows: After a loading dose (if necessary) of aspirin and a P2Y12 inhibitor, aspirin 100 mg and a P2Y12 inhibitor daily will be indicated for 1 month in both ACS and Chronic Coronary Syndrome (CCS). Patients with high ischemic risk could be extended to 3 months. After DAPT, SAPT will be continued with the drug of choice, preferably P2Y12 inhibitor. Patients requiring chronic anticoagulation will receive triple therapy only during hospitalization. At release, an oral anticoagulant (NOAC preferred over VKA) will be indicated along with 6 months of SAPT with a P2Y12 inhibitor.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sirolimus eluting stent
Description: Size (diameter and length) will be chosen at operator's discretion aided by simple angiography, QCA, or intravascular image; so that the lesion previously prepared and 2 mm at each end are covered by DES with an stent to artery ratio of 1.1. Post-dilatation will be performed when indicated. Device will be used in accordance with the CE mark instructions.~All patients will receive DAPT as follows: After a loading dose (if necessary) of aspirin and a P2Y12 inhibitor, aspirin 100 mg and a P2Y12 inhibitor daily will be indicated for 1 month in both ACS and CCS. Patients with high ischemic risk could be extended to 3 months. After DAPT, SAPT will be continued with the drug of choice, preferably P2Y12 inhibitor. Patients requiring chronic anticoagulation will receive triple therapy only during hospitalization. At release, an oral anticoagulant (NOAC preferred over VKA) will be indicated along with 6 months of SAPT with a P2Y12 inhibitor.
Study: NCT06075082

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LEFT smartwatch app
Description: The LEFT smartwatch app is an app on the Apple Watch which measures body sleep position and gently vibrates when the body is in the right lateral decubitus position. In this way, patients with nocturnal gastroesophageal reflux symptoms learn to avoid the right lateral sleep position as they will avoid the annoying vibrations. Measurements while using the smartwatch app will be compared to measurements at baseline.
Study: NCT04906733

Intervention type: PROCEDURE
Intervention: Tumor biopsy
Description: Patients with RAS/RAF wild-type metastatic right colon cancer will receive biopsy before the standard treatment of chemotherapy or target therapy.
Study: NCT06446830

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: multimodal analgesia and vitamin B
Description: B1, B6 , B9 , B12 in addition to the routine paracetamol and NSAID

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard multimodal analgesia
Description: Routine Paracetamol and NSAID
Study: NCT06269406

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ibuprofen 400 mg in combination with Curcumin covered with liquorice root 100 mg
Description: The combination of ibuprofen 400 mg and Curcumin covered with liquorice root 100 mg in patients after 2-4 molars procedure

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ibuprofen 200 mg in combination with Curcumin covered with liquorice root 100 mg
Description: The combination of ibuprofen 200 mg and Curcumin covered with liquorice root 100 mg in patients after 2-4 molars procedure

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: The combination of ibuprofen 400 mg and placebo in patients after 2-4 molars procedure
Description: The combination of ibuprofen 400 mg and placebo 100 mg in patients after 2-4 molars procedure
Study: NCT05768568

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual Toothbrush and Powered Toothbrush
Description: Manual Toothbrush will be mechanically (hand) driven Powered Toothbrush will be battery operated

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual Toothbrush and Powered Toothbrush
Description: Manual Toothbrush will be mechanically (hand) driven Powered Toothbrush will be battery operated
Study: NCT06038942

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Formal mindfulness instruction
Description: An equal number of university students from all groups will participate in this arm (i.e., those with ADHD, those with a history of nonsuicidal self-injury, and those with self-reported stress). The formal mindfulness instruction will consist of four weekly 1 hour-long group sessions, held on Webex (i.e., online) over four consecutive weeks. Participants will learn foundational principles around the role of mindfulness in relation to emotion regulation, stress, and self-compassion.~They will also be taught formal mindfulness practices (e.g., sitting meditation, body scan, thought meditation, loving-kindness meditation) during the group sessions and will be asked to commit to practicing the strategies independently throughout the project period.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Informal mindfulness instruction
Description: An equal number of university students from all groups will participate in this arm (i.e., those with ADHD, those with a history of nonsuicidal self-injury, and those with self-reported stress). The informal mindfulness instruction will consist of four weekly 1 hour-long group sessions, held on Webex (i.e., online) over four consecutive weeks. Participants will learn foundational principles around the role of mindfulness in relation to emotion regulation, stress, and self-compassion.~They will also be taught how to integrate informal mindfulness into their daily routine and will be guided through a series of demonstrations within the group sessions. Participants will be asked to commit to practicing informal mindfulness independently throughout the project period.
Study: NCT04739800

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cediranib Maleate
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cediranib Maleate
Description: Given PO
Study: NCT05968794

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vaginal cerclage
Description: A vaginal cerclage is a short and minor surgical procedure performed under general or regional anesthesia. An unabsorbable suture is placed around/through the cervix to close the cervical canal and to increase its firmness, in order to reduce cervical insufficiency.
Study: NCT05977569

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prolonged Fasting
Description: Participants are asked to refrain from caloric intake for 3 days following a period of habitual lifestyle assessment and metabolic assessment.
Study: NCT04739800

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cediranib Maleate
Description: Given PO

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography with Contrast
Description: Undergo CT with contrast

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography with Contrast
Description: Undergo CT with contrast

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography with Contrast
Description: Undergo CT with contrast

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography with Contrast
Description: Undergo CT with contrast

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Echocardiography
Description: Undergo ECHO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo ECHO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo ECHO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo ECHO

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT04739800

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT05821868

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dosivent
Description: Dosivent® inhalation chamber is designed to optimize the delivery of inhaled bronchodilators and corticosteroids in the treatment of respiratory diseases
Study: NCT05719415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Measurement of pulmonary functional capillary surface area
Description: Measurement of transpulmonary metabolism of trace injected doses of benzoyl-Phe-Ala-Pro
Study: NCT05557240

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NeoPep Vaccine1 plus Poly-ICLC
Description: NPVAC1： NPVAC1 drug products are composed of 5 peptides from the HCMV warehouse， NPVAC1 vaccine will be applied before maintenance TMZ cycles after completion of chemoradiation therapy (CRT). Beginning on day 14 before the first maintenance TMZ cycle, patients will receive 7 vaccinations with NPVAC1 drug products during 6 weeks. 400 μg per peptide per vial are used.~Poly-ICLC:~Poly-ICLC（500ug）will be used as immunomodulator with all vaccinations.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NeoPep Vaccine2 plus Poly-ICLC
Description: NPVAC2： NPVAC2 will be ready for use 2 months after enrollment, as these peptides have to be newly synthesized for each patient following identification of the mutanome and corresponding mutated peptides in the HLA ligandome. NPVAC2 drug products are composed 20 peptides de novo synthesized for an individual patient. Patients will be repeatedly vaccinated with NPVAC2 drug products beginning on day 33 of the 6 maintenance TMZ cycle.Patients will receive 9 vaccinations within 12 weeks. 400 μg per peptide per vial are used.~Poly-ICLC:~Poly-ICLC（500ug）will be used as immunomodulator with all vaccinations.
Study: NCT05821868

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Aerochamber Plus Flow Vu
Description: Aerochamber Plus Flow Vu® inhalation chamber is also designed to optimize the delivery of inhaled bronchodilators and corticosteroids in the treatment of respiratory diseases
Study: NCT04739800

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT04980859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zebutinib&BR or Zebutinib&FCR
Description: Introduction period: Zebutinib 160 mg bid oral treatment for 3 months;Joint stage :6 sessions of Zebutinib FCR( under 60 years of age,Fludarabine 25 mg/m² Q3W, Cyclophosphamide 250 mg/m² Q3W,Rituximab 375 mg/m² Q3W) or BR (over 60 years of age, )(28 days and 1 cycle);Maintenance treatment: after the end of the combined phase, continue the treatment of zebutinib.
Study: NCT04739800

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Multigated Acquisition Scan
Description: Undergo MUGA

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multigated Acquisition Scan
Description: Undergo MUGA

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multigated Acquisition Scan
Description: Undergo MUGA

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: Given PO

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pegylated Liposomal Doxorubicin Hydrochloride
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topotecan Hydrochloride
Description: Given IV
Study: NCT06607848

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-Add EDOF IOL
Description: Acunex Vario AN6V

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EDOF IOL
Description: PureSee EDOF IOL
Study: NCT06608628

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Experimental Group
Description: The experimental group students will play a patient safety escape room game. Control group students will be given traditional education. The knowledge level and team cooperation of the two groups will be compared.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Group
Description: The experimental group students will play a patient safety escape room game. Control group students will be given traditional education. The knowledge level and team cooperation of the two groups will be compared.
Study: NCT06608784

Intervention type: DIAGNOSTIC_TEST
Intervention: Electrocardiography
Description: 12-lead electrocardiography

Intervention type: DIAGNOSTIC_TEST
Intervention: Electrocardiography
Description: 12-lead electrocardiography

Intervention type: DIAGNOSTIC_TEST
Intervention: Electrocardiography
Description: 12-lead electrocardiography
Study: NCT06037785

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Paced Self-Management (SPSM)
Description: (SPSM) consists of two components: 1) HR Self-monitoring, and 2) online Shock Management modules (N=4) with weekly telephone coaching, completed over 1 month.
Study: NCT06607822

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A patient-centered assistant system based on Large-Language Model (LLM)
Description: Participants will engage in a 10-minute medical consultation using LLM model interface embedded in a tablet device before their regular face-to-face consulation with physicians. During the trials, participants could engage in free conversations covering aspects including risk factors, symptoms, diagnosis, examinations, treatment, advice and caution, etc. Participants who have completed the ophthalmic imaging examination will be asked to input results into the assistant model to generate structured reports.
Study: NCT06609018

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test Lenses (stenfilcon A)
Description: Daily disposable, soft contact lenses worn for one week

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test Lenses (stenfilcon A)
Description: Daily disposable, soft contact lenses worn for one week

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Control Lenses (omafilcon A)
Description: Daily disposable, soft contact lenses worn for one week

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Control Lenses (omafilcon A)
Description: Daily disposable, soft contact lenses worn for one week
Study: NCT06606665

Intervention type: OTHER
Intervention: Cognitive skills test
Description: Cognitive skills; It will be evaluated with the Montreal Cognitive Assessment Scale.

Intervention type: OTHER
Intervention: Cognitive skills test
Description: Cognitive skills; It will be evaluated with the Montreal Cognitive Assessment Scale.

Intervention type: OTHER
Intervention: Reaction time test
Description: Reaction time; It will be evaluated with the 12-Red Square Test on the App-coo test application via tablet.
Study: NCT05219526

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: blood glucose measurement: BGM
Description: measurement of blood glucose concentration using different BGM

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: blood glucose measurement: reference method
Description: measurement of blood glucose concentration using reference Method
Study: NCT04778722

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oral probiotics
Description: containing four Lactobacillus strains (Lactobacillus crispatus -Lbv88, Lactobacillus rhamnosus -Lbv96, Lactobacillus jensenii -Lbv116, and Lactobacillus gasseri -Lbv150)
Study: NCT06209645

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS (Transcranial Direct Current Stimulation)
Description: The tDCS group will be treated with non-invasive motor cortex stimulation. A two-minute EEG recording will be made before each session, using the same electrodes as for stimulation. Anodal stimulation of 2,0 mA will be delivered over the motor area contralateral to the painful region (C4 or C3 according to the international 10-20 system). The return electrode will be placed over the fronto-polar region (FP1 or FP2) ipsilateral to the painful region. If pain is bilateral, the most painful region will be chosen to be treated.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS (Transcranial Direct Current Stimulation)
Description: The tDCS group will be treated with non-invasive motor cortex stimulation. A two-minute EEG recording will be made before each session, using the same electrodes as for stimulation. Anodal stimulation of 2,0 mA will be delivered over the motor area contralateral to the painful region (C4 or C3 according to the international 10-20 system). The return electrode will be placed over the fronto-polar region (FP1 or FP2) ipsilateral to the painful region. If pain is bilateral, the most painful region will be chosen to be treated.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tACS (Transcranial Alternating Current Stimulation)
Description: The tACS group will be treated with non-invasive motor cortex stimulation. The stimulation series comprises six sessions spaced 2 weeks apart, the first session being placebo. A two-minute EEG recording will be made before each session, using the same electrodes as for stimulation. Stimulation frequency will be set according to the dominant frequency recorded over the motor area. Anodal stimulation of 2,0 mA will be delivered over the motor area contralateral to the painful region (C4 or C3 according to the international 10-20 system). The return electrode will be placed over the fronto-polar region (FP1 or FP2) ipsilateral to the painful region.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tACS (Transcranial Alternating Current Stimulation)
Description: The tACS group will be treated with non-invasive motor cortex stimulation. The stimulation series comprises six sessions spaced 2 weeks apart, the first session being placebo. A two-minute EEG recording will be made before each session, using the same electrodes as for stimulation. Stimulation frequency will be set according to the dominant frequency recorded over the motor area. Anodal stimulation of 2,0 mA will be delivered over the motor area contralateral to the painful region (C4 or C3 according to the international 10-20 system). The return electrode will be placed over the fronto-polar region (FP1 or FP2) ipsilateral to the painful region.
Study: NCT06606665

Intervention type: OTHER
Intervention: Reaction time test
Description: Reaction time; It will be evaluated with the 12-Red Square Test on the App-coo test application via tablet.
Study: NCT05736107

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBL-514 Injection
Description: Formulated as an injectable CBL-514 solution at a concentration of 5 mg/mL.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% Sodium Chloride
Description: Sodium Chloride (0.9% NaCl) placebo for injection
Study: NCT06387745

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hepatoscope
Description: The Hepatoscope is a non-invasive external ultrasound imaging device, intended for general purpose pulse echo ultrasound imaging, and soft tissue elasticity imaging of the human body. In addition, the Hepatoscope provides measurements of shear wave speed and tissue stiffness, ultrasound beam attenuation and estimates of speed of sound, in internal structures of the body.