TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06170736

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Doppler-Guided Haemorrhoidal Artery Ligation
Description: The principle consists of locating the signal emitted by the haemorrhoidal arteries using a Doppler probe. Once identified, the arteries are ligated in order to remove the arterial vascularization of the haemorrhoidal bundles. The treatment of the prolapse is reinforced by a folding of the mucosa of the lower rectum, called mucopexy.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation
Description: The principle consists of inserting a metal probe under the mucosa of the anus, in contact with the haemorrhoidal bundles to be treated. A source of radiofrequency is then delivered through this probe in contact with the haemorrhoidal veins which will be sclerosed. The procedure is repeated for each haemorrhoidal bundle to be treated.
Study: NCT06122532

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stem cell preparation combined with Reticular skin
Description: The dose of transplanted stem cells per wound (100cm2) is 1×10\^6, then cover the wound with autologous regular skin.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stem cell preparation combined with MEEK skin
Description: The dose of transplanted stem cells per wound (100cm2) is 1 × 10 \^ 6, then cover the wound with autologous MEEK skin.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stem cell preparation combined with split-thickness skin
Description: The dose of transplanted stem cells per wound (100cm2) is 1 × 10 \^ 6, then cover the wound with autologous split-thickness skin.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: autologous skin grafting
Description: After cleaning the wound, use autologous skin (Reticular skin/MEEK skin/split-thickness skin) grafting and cover the wound surface。
Study: NCT05240833

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: VExUS Score
Description: The VExUS-Guided Arm care team will be informed of the Day 0 VExUS immediately after the ultrasound is performed and given a suggested target for the following 48 hours as follows:~* VExUS 0: There is no evidence of venous congestion.~* VExUS 1: There is evidence of mild venous congestion. The investigators recommend targeting a net neutral or negative fluid balance with diuresis.~* VExUS 2-3: There is evidence of moderate to severe venous congestion. The investigators recommend targeting a fluid balance of negative 1-2L with diuresis.~* If the investigator cannot obtain ultrasound images of sufficient quality to calculate VExUS, the care team will be informed that there is no recommendation for that subject on that day.
Study: NCT04879758

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genetic Risk Estimate
Description: The genetic risk information includes individual remaining-lifetime and 10-year genetic risk estimates for T2D as well as a dichotomized genetic risk category: 'increased genetic risk' (if their genetic risk is higher than the average population risk) or 'no increased genetic risk' (if their genetic risk is not higher than the average population risk).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Genetic Risk Estimate + Fitbit Functions
Description: The genetic risk information includes individual remaining-lifetime and 10-year genetic risk estimates for T2D as well as a dichotomized genetic risk category: 'increased genetic risk' (if their genetic risk is higher than the average population risk) or 'no increased genetic risk' (if their genetic risk is not higher than the average population risk).~The two unique Fitbit functions are step goal setting and prompts. Individualized daily step goals will be set to be 10% higher than participants' own baseline Fitbit step counts. The 'Reminder To Move' function of Fitbit will be used as a prompt to remind participants to reduce sedentary time and walk at least 250 steps/hour within a specified timeframe (i.e., from 9am to 10pm in the proposed research). If the user has not accumulated at least 250 steps/hour, a reminder (for example, 150 steps to go) will appear on the Fitbit screen at 10 minutes before the hour (for example, at 10:50 a.m.) and cause the device to vibrate.
Study: NCT05554536

Intervention type: PROCEDURE
Group type: OTHER
Intervention: PEEP titration trial
Description: PEEP trial, starting from clinical PEEP 16 cmH2O and ending at PEEP 6 cmH2O. The PEEP trial will be stopped for haemodynamic instability (defined as arterial pressure \< 80 mmHg and /or heart rate \> 150 bpm) or desaturation (defined as SpO2 \< 92%).
Study: NCT05971160

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Financial education videos
Description: Brief videos providing structured information on managing one's money

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Financial education videos
Description: Brief videos providing structured information on managing one's money

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Financial education videos
Description: Brief videos providing structured information on managing one's money

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Microgrant
Description: $150 stipend

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Microgrant
Description: $150 stipend

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Microgrant
Description: $150 stipend

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Peer mentoring
Description: One-on-one structured mentoring sessions with a trained peer
Study: NCT05107479

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COVID-19 Vaccine IVR Training
Description: The intervention consists of 5 interactive voice response (IVR) modules conveying information about COVID-19 vaccines and vaccine administration best practices. Module topics include the following: 1) the importance of COVID-19 vaccines and recipient eligibility, 2) overview of and differences between approved COVID-19 vaccines , 3) surveillance of adverse vaccine events, 4) organizing a vaccination site, and safe storage and handling COVID-19 vaccines, and 5) micro planning and communication strategies for COVID-19 vaccination efforts. The training will be offered in five local languages: French, Lingala, Swahili, Kikongo, and Tshiluba.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Condition
Description: The control arm will receive the COVID-19 Vaccine IVR Training after an estimated month-long delay. The control arm will be told upon completion of the baseline survey that the training will commence at a later estimated date and will not receive any additional information until the treatment group completes training.
Study: NCT05362682

Intervention type: OTHER
Intervention: Sinopharm Vaccine
Description: Sinopharm Vaccine will be administered by the Govt as part of COVID-19vaccination campaign

Intervention type: OTHER
Intervention: Sinopharm Vaccine
Description: Sinopharm Vaccine will be administered by the Govt as part of COVID-19vaccination campaign
Study: NCT05635318

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FDA approved medications for ADHD plus Quantitative EEG Neurofeedback
Description: A mathematical approach to analyzing EEG data, called quantitative electroencephalography (qEEG), can be used to develop a visual map of the type and location of brain waves or rhythms. Other more specific wave patterns, such as event-related potentials, can also be seen in the EEG.NF converts signals such as EEG into visual or auditory information, and then subjects selectively enhance or inhibit certain components through training. There are three common NF protocols for ADHD: theta/beta training, sensorimotor rhythm (SMR) training, and slow cortical potentials (SCP) training.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: FDA approved medications for ADHD
Description: Ritalin (methylphenidate HCl); Ritalin LA, Ritalin SR Strattera (atomoxetine HCl)
Study: NCT05257824

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin 100mg
Description: 1. short-term dual antiplatelet: dual antiplatelet agents for 6 months~2. long-term dual antiplatelet: dual antiplatelet agents for 12 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin 100mg
Description: 1. short-term dual antiplatelet: dual antiplatelet agents for 6 months~2. long-term dual antiplatelet: dual antiplatelet agents for 12 months

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clopidogrel 75mg
Description: 1. short-term dual antiplatelet: dual antiplatelet agents for 6 months~2. long-term dual antiplatelet: dual antiplatelet agents for 12 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clopidogrel 75mg
Description: 1. short-term dual antiplatelet: dual antiplatelet agents for 6 months~2. long-term dual antiplatelet: dual antiplatelet agents for 12 months
Study: NCT05083260

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NE3107
Description: NE3107 is an investigational orally bioavailable, blood-brain barrier permeable anti-inflammatory agent with a new mechanism of action targeting multiple mechanisms of pathology in Parkinson's disease

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Hard gelatin capsule containing only common excipients for oral formulations
Study: NCT06286540

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lymphoblock
Description: 1 time per surgery with the exposition for 20 minutes.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 time per surgery with the exposition for 20 minutes.
Study: NCT05091944

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: web-based birth decision aid
Description: Women in the intervention group receive both usual care and decision support (an interactive web-based birth decision aid). The innovative interactive web-based birth decision aid comprised five components: Component 1-a communication aid video involves 2 expert's talk about how to participate in SDM and prepare self with choice talk, option talk and decision talk(10 minutes )and practice communication skills with clinician(10 minutes); Component 2-overall of the function and features of birth decision aid. Component 3-introduce the benefits and risk of vaginal birth after cesarean; Component 4- the benefits and risk of elective repeat cesarean section; Component 5 -a quit to confirm women's knowledge regarding the two choices and confirm women's values.
Study: NCT02841293

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biological mesh
Description: The intervention consists of suturing a biological mesh in the pelvic floor defect. The mesh will be sutured at each side of the coccyx or distal sacrum and directly to the residual pelvic floor muscle and fascia by using interrupted or continuous hand-sewn sutures with an appropriate amount of tension. The mesh that will be used is the Cellis prosthesis from Meccellis Biotech, reference C1015E which size is 10x15cm.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary perineal wound closure
Description: The intervention consists of stitching the ischioanal and subcutaneous fat using interrupted Vicryl sutures in one or two layers similar to primary perineal closure
Study: NCT06320873

Intervention type: OTHER
Group type: OTHER
Intervention: archery respiratory parameters
Description: Evaluation of respiratory functions, respiratory muscle strength and shooting performance in archers
Study: NCT05458219

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI343
Description: IBI343 will be administered intravenously (IV) on Day 1 of every 21-day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI343
Description: IBI343 will be administered intravenously (IV) on Day 1 of every 21-day cycle.
Study: NCT05296096

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Protein dosage and rehabilitation team delivered exercise prescription
Description: The dietitian and rehabilitation team will be consulted on enrollment and will assess the patient for nutritional and functional status using the institutional criteria and physical exam. The study dietitian will prescribe the protein goal based on the randomization assignment and age group. For the high protein arm, protein goals will be 3g/kg/day for ages 1-1yrs, and 2.4g/kg/day for ages greater than 12 years.~The rehabilitation team will determine the appropriate highest level of mobility (HLM) for the day in collaboration with the medical team on morning rounds. The rehabilitation team will prescribe passive or active participation in two 30-minute HLM sessions, individualized to their baseline function and clinical status and/or restrictions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Protein dosage and rehabilitation team delivered exercise prescription
Description: The dietitian and rehabilitation team will be consulted on enrollment and will assess the patient for nutritional and functional status using the institutional criteria and physical exam. The study dietitian will prescribe the protein goal based on the randomization assignment and age group. For the high protein arm, protein goals will be 3g/kg/day for ages 1-1yrs, and 2.4g/kg/day for ages greater than 12 years.~The rehabilitation team will determine the appropriate highest level of mobility (HLM) for the day in collaboration with the medical team on morning rounds. The rehabilitation team will prescribe passive or active participation in two 30-minute HLM sessions, individualized to their baseline function and clinical status and/or restrictions.
Study: NCT05580978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GEM
Description: The intervention group will be given Libre 2 supplies for 4 months, an activity monitor, and the 4-chapter GEM paper guide. The intervention group will complete a virtual or inperson study visit where they will receive instructions on how to apply their unblinded Freestyle Libre and connect it to the study account, as well as how to register their Fitbit to the study account. Participants will receive one telephone call to review use of the GEM Guide and call at two weeks and six weeks later when the probability of dropouts from lifestyle intervention peaks. Participants will follow the self-directed GEM guide for 4 months (a 1-month treatment period followed by a 3-month maintenance period) while wearing a FitBit activity monitor and a Freestyle Libre 2 CGM.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Care
Description: Participant's current prediabetes treatment.
Study: NCT05629494

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibuprofen 400 mg, TID
Description: Participants will receive Ibuprofen 400 mg 3 times per day for 10 days.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: PSA test
Description: PSA test will be repeated in 6 weeks

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PSA test
Description: PSA test will be repeated in 6 weeks
Study: NCT04852679

Intervention type: DRUG
Group type: OTHER
Intervention: Lanreotide autogel
Description: Administered as deep subcutaneous (SC) injections
Study: NCT05705154

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychology interventions
Description: Based on clinical expertise and theory, it is anticipated the following elements may be included in the intervention:~* Progressive breathing pattern retraining, including education, self-observation, relaxation, body scanning, postural re-alignment~* Identifying the connections between body and mind to address anxiety and breathlessness~* Coping skills for managing anxiety using principles from narrative therapy and mindfulness~* Online materials to improve self-efficacy with home practice~* Social connection with other CYP for peer support, and resource sharing~* Activities to help CYP reconnect with their usual activities, skills, abilities, interests, support systems.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychology interventions
Description: Based on clinical expertise and theory, it is anticipated the following elements may be included in the intervention:~* Progressive breathing pattern retraining, including education, self-observation, relaxation, body scanning, postural re-alignment~* Identifying the connections between body and mind to address anxiety and breathlessness~* Coping skills for managing anxiety using principles from narrative therapy and mindfulness~* Online materials to improve self-efficacy with home practice~* Social connection with other CYP for peer support, and resource sharing~* Activities to help CYP reconnect with their usual activities, skills, abilities, interests, support systems.
Study: NCT05637047

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: pulsed radiofrequency
Description: ultrasound-guided intramuscular and interfascial pulsed radiofrequency ablation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dry needling
Description: ultrasound-guided intramuscular and interfascial dry needling
Study: NCT06304792

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Immediate FET in a stimulated or programmed cycle
Description: Patients will undergo FET in the cycle immediately following oocyte retrieval and a failed fresh embryo transfer or freeze all.
Study: NCT06069349

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early Rehabilitation
Description: Early Rehabilitation for patients after cardiac surgery

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: usual treatment
Description: Patients are not allowed to exercise Early Rehabilitation
Study: NCT05450003

Intervention type: DEVICE
Group type: OTHER
Intervention: Irrigation activation using xp endo finisher file , new sonic eddy tip and conventional needle syringe irrigation
Description: irrigation activation using 3 different irrigation activation systems including xp endo finisher file , new sonic eddy system and conventional needle syringe irrigation

Intervention type: DEVICE
Group type: OTHER
Intervention: Irrigation activation using xp endo finisher file , new sonic eddy tip and conventional needle syringe irrigation
Description: irrigation activation using 3 different irrigation activation systems including xp endo finisher file , new sonic eddy system and conventional needle syringe irrigation

Intervention type: DEVICE
Group type: OTHER
Intervention: Irrigation activation using xp endo finisher file , new sonic eddy tip and conventional needle syringe irrigation
Description: irrigation activation using 3 different irrigation activation systems including xp endo finisher file , new sonic eddy system and conventional needle syringe irrigation
Study: NCT06173635

Intervention type: DEVICE
Group type: OTHER
Intervention: Maxi Move 5
Description: 4 comparative devices will be used to evaluate the MM5 device
Study: NCT06295627

Intervention type: OTHER
Intervention: There were no interventions in retrospective analysis
Description: A retrospective analysis method was used to analyze the causes of catheter-related urinary tract infection and the infecting bacteria of the two groups of patients. A single factor analysis was performed on various factors and other related factors, and corresponding nursing strategies were summarized and proposed.

Intervention type: OTHER
Intervention: There were no interventions in retrospective analysis
Description: A retrospective analysis method was used to analyze the causes of catheter-related urinary tract infection and the infecting bacteria of the two groups of patients. A single factor analysis was performed on various factors and other related factors, and corresponding nursing strategies were summarized and proposed.
Study: NCT05248256

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evidence-based radiation dose limitation to the vertebral bone marrow
Description: The only intervention that will occur during the radiation treatment planning process will be the application of evidence-based radiation dose limitations to the vertebral bone marrow during treatment plan optimization in order to attempt to limit Grade 3 Lymphopenia (G3L) toxicity.
Study: NCT06221592

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: defocus spectacle lenses
Description: To evaluate the differences in controlling the progression of myopia in adolescents and the safety and comfort of wearing different types of defocus incorporated multiple segments spectacle lenses, to explore the feasibility of effective defocus micro lens design, and apply personalized defocus frame lenses for myopia prevention and control.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: defocus spectacle lenses
Description: To evaluate the differences in controlling the progression of myopia in adolescents and the safety and comfort of wearing different types of defocus incorporated multiple segments spectacle lenses, to explore the feasibility of effective defocus micro lens design, and apply personalized defocus frame lenses for myopia prevention and control.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: defocus spectacle lenses
Description: To evaluate the differences in controlling the progression of myopia in adolescents and the safety and comfort of wearing different types of defocus incorporated multiple segments spectacle lenses, to explore the feasibility of effective defocus micro lens design, and apply personalized defocus frame lenses for myopia prevention and control.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: defocus spectacle lenses
Description: To evaluate the differences in controlling the progression of myopia in adolescents and the safety and comfort of wearing different types of defocus incorporated multiple segments spectacle lenses, to explore the feasibility of effective defocus micro lens design, and apply personalized defocus frame lenses for myopia prevention and control.
Study: NCT05674916

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Point-of-care ultrasound-driven diagnostic pathway
Description: Focused lung ultrasound will include 8 zones (anterior and lateral) and evaluate pneumothorax, interstitial syndrome, lung consolidation, and pleural effusion. Focused cardiac ultrasound will include four views (subxiphoid four-chamber view, parasternal long-axis view, parasternal short-axis view, and apical four-chamber view) and evaluate pericardial fluid, right ventricle dilation, and left ventricular systolic contractility.
Study: NCT05856149

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Diabetes Prevention Program
Description: The intervention is a mobile, web-based diabetes prevention program that participants will have access to for a total of 12 weeks. The intervention is a behavioral intervention aimed at increasing the knowledge and skills of participants to reduce type 2 diabetes risk behaviors.