TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05964725

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Receive traditional medical therapy and transcranial direct current stimulation
Description: Equipment used: Bricon tDCS stimulator, high-precision electrode stimulation method Stimulant dose: 1.5mA Stimulation time: 20 minutes/time, continuous treatment for 5 days Stimulation course: 5 days/course Stimulation target: left auditory cortex area, i.e., under system 10-20, left T3 position.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Receive traditional medical therapy and sham stimulation
Description: By controlling the tDCS stimulator to mimic only the first 30 seconds of tDCS stimulation, after 30 seconds of pathway resistance control, so that the stimulation intensity is below the threshold, without giving real stimulation, in this process, the position of the stimulation target is not changed, and the rest of the operation is the same.
Study: NCT05684978

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Perampanel
Description: The purpose of this study is to determine the efficacy of Perampanel, an approved antiseizure medication, in the treatment of refractory status epilepticus (RSE), to identify determinants of outcomes, and establish safety.
Study: NCT06482645

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Perilesional/regional systematic biopsy
Description: The biopsy procedure was conducted by a highly skilled and experienced urologist who specializes in performing prostate biopsies. Prophylactic antibiotics were routinely used both before and one day prior to scheduled surgery. Each patient was placed in the left lateral position or lithotomy position. For each predefined mpMRI suspicious lesion, urologists obtained nine cores at 5-mm intervals within and around the region of interest (penumbra). The location of these nine cores depended on the shape and location of the suspicious lesion.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combination of systematic biopsy and targeted biopsy
Description: The biopsy procedure was conducted by a highly skilled and experienced urologist who specializes in performing prostate biopsies. Prophylactic antibiotics were routinely used both before and one day prior to scheduled surgery. Each patient was placed in the left lateral position or lithotomy position. The ultrasound equipment used included a color Doppler ultrasound diagnostic instrument (Hitachi HiVision, Philips Epiq 7), transrectal probes, and corresponding puncture needle guns. Color Doppler examination was performed from the base to the apex. Three to five targeted biopsies from the lesion were performed within and around the predefined mpMRI suspicious lesion, followed by fore-zone 12-core biopsy.
Study: NCT05993754

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-pharmacological intervention
Description: The intervention consists of six main elements:~Correction of sensory deficits: Before surgery, the use of glasses, hearing aids and/or removable dental prostheses will be allowed, which will be removed before starting anesthesia in the emergency room. After surgery, they will be delivered back to the user.~Reorientation: In the postoperative period, the person will be informed where they are and the visit of the companion will be coordinated.~Early mobilization: A protocolized mobilization routine will be applied according to pain, state of consciousness, risk of thromboembolic disease and risk of falls.~Environmental management: You will be shown the time on a clock, it will reinforce the idea of the place where you are and that you can count on the team in case you need assistance.~Sleep protocol: The elderly person who does not want or cannot perform the mobilization routine, non-pharmacological sleep will be privileged.~Reduction of anticholinergic drugs
Study: NCT05032963

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Overnight polysomnography examinations
Description: sleep lab for overnight polysomnography examinations

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Overnight polysomnography examinations
Description: sleep lab for overnight polysomnography examinations
Study: NCT05814770

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Finerenone
Description: The participants were randomized in an equal ratio to receive finerenone 10 mg once daily. Patients received the initial dose of study drug for the first 4 weeks of randomized treatment period. Thereafter, the dose of study medication was not changed for patients with adequate BP control. For patients not meeting BP \< 140/90 mmHg at week 4, the dose of study medication was increased to finerenone 20 mg once daily. If BP \> 160/110 mmHg at the time of 8 weeks follow-up, nifedipine 30mg once day was added.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Spironolactone
Description: The participants were randomized in an equal ratio to receive spironolactone 20 mg twice daily. Patients received the initial dose of study drug for the first 4 weeks of randomized treatment period. Thereafter, the dose of study medication was not changed for patients with adequate BP control. For patients not meeting BP \< 140/90 mmHg at week 4, the dose of study medication was increased to spironolactone 40 mg twice daily. If BP \> 160/110 mmHg at the time of 8 weeks follow-up, nifedipine 30mg once day was added.
Study: NCT05588362

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fitz Frames 3-D Printed Glasses
Description: The intervention group will order glasses directly in the office following their exam and consent using an iPad with the help of the research assistant. The iPad will be e-connected to a 3D printed glasses manufacturer (Fitz Frames) through their application, allowing the child (with assistance from the doctor or research assistant) to take various measurements in real time. Sixteen different measurements will be taken including interpupillary distance, face length, face width, and temple measures. The child will be able to choose frame style and order it directly from the manufacturer immediately following the exam. Glasses will be shipped directly to the patient's home (shipping address will be input to the app by the family).
Study: NCT06029166

Intervention type: DEVICE
Group type: OTHER
Intervention: Insertable subcutaneous cardiac monitor (BIOMONITOR IIIm®, Biotronik®)
Description: Implantation of a subcutaneous cardiac monitor (BIOMONITOR IIIm®, Biotronik®) before beginning the Bruton's tyrosine kinase inhibitor treatment.
Study: NCT05266287

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: a supplement containing 2'-fucosyllactose (2'-FL)
Description: Participants will be asked to take a commercially available dietary supplement containing 833 mg of 2'-FL, 220 mg of a blend of organic beet root and okra fruit, 100 mg of Collinsonia root, 37.5 mg organic rice hull concentrate, and 14 mg calcium stearate.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Supplement
Description: Participants will be asked to take a placebo supplement containing 510.9 mg organic sucanat, 385.4 mg calcium phosphate, 304.7 mg cellulose, 143.4 mg date powder, 39.4 mg rice bran powder, 9.0 mg gum arabic, and 7.2 mg calcium stearate.
Study: NCT04968925

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE Oasys 1-Day
Description: TEST
Study: NCT05621460

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 50mL still water
Description: Drink 50mL still water immediately prior to head-up tilt test

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 50mL still water
Description: Drink 50mL still water immediately prior to head-up tilt test
Study: NCT05400720

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mentoring
Description: At least one meeting between the mentor and mentee will occur to share experiences and see if the mentee would like to continue meeting with a mentor
Study: NCT05377710

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: sinus lift with lateral approach
Description: Maxillary sinus floor augmentation or sinus lift is a surgical procedure, which provides a solution to the problem of sinus bone loss (too thin), and thus increases the thickness of the bone for immediate or subsequent implant placement in the premolars and molars (4). It consists of the elevation of the sinus mucosa that lines the maxillary sinus. The space thus freed will be filled with a bone filling material
Study: NCT05188963

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intermittent catheterization
Description: Intermittent catheterization is performed as treatment for urinary retention. Treatment is stopped when postvoid urinary retention volume is below the threshold of each group.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intermittent catheterization
Description: Intermittent catheterization is performed as treatment for urinary retention. Treatment is stopped when postvoid urinary retention volume is below the threshold of each group.
Study: NCT05801926

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Heel2Toe[TM] sensor
Description: Heel2Toe is a new generation of wearables that provides real-time auditory feedback when the person takes a good step, one in which the step is initiated with a strong heel strike.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Heel2Toe[TM] sensor
Description: Heel2Toe is a new generation of wearables that provides real-time auditory feedback when the person takes a good step, one in which the step is initiated with a strong heel strike.
Study: NCT04968925

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE Oasys 1-Day
Description: TEST

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Precision 1
Description: CONTROL

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Precision 1
Description: CONTROL
Study: NCT05534555

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: FebriDx
Description: Testing of finger-prick blood sample using FebriDx
Study: NCT05621460

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 50mL still water
Description: Drink 50mL still water immediately prior to head-up tilt test
Study: NCT05023798

Intervention type: DEVICE
Intervention: ATD (device test)
Description: Medical device test (no intervention)
Study: NCT04961840

Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study.

Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study.

Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study.
Study: NCT05155787

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neurofeedback
Description: Neurofeedback training as a method is going to let the brain producing the alpha signal (8-13 Hz).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Shame neurofeedback
Description: shame neurofeedback
Study: NCT04994132

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Scan
Description: Undergo bone scan

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Scan
Description: Undergo bone scan

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given IV or PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given IV or PO

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dactinomycin
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dactinomycin
Description: Given IV
Study: NCT04257695

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TapPro
Description: Manualized intervention administered by a clinician to facilitate opioid tapering during clinical visits.
Study: NCT05212987

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FCN-098
Description: FCN-098 will be given orally in ascending doses starting at 40 mg Q12h until the maximum tolerated dose or recommended dose is reached.
Study: NCT04994132

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT05428696

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2080
Description: Powder-in-capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2080
Description: Powder-in-capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2080
Description: Powder-in-capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2080
Description: Powder-in-capsule
Study: NCT04722224

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based pulmonary rehabilitation
Description: The reabilitAR program includes the self-management educational program Living Well with COPD. The exercise training will include endurance, resistance/strength, flexibility and balance training.
Study: NCT05758142

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Potassium Chloride
Description: Oral administration of potassium chloride tablets

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Potassium Chloride
Description: Oral administration of potassium chloride tablets

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Potassium Chloride
Description: Oral administration of potassium chloride tablets

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral administration of inert placebo tablets
Study: NCT06536855

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Gardasil 9
Description: GARDASIL 9 is a vaccine indicated in females 9 through 45 years of age for the prevention of cervical, vulvar, vaginal, anal, oropharyngeal and other head and neck cancers caused by human papillomavirus (HPV) Types 16, 18, 31, 33, 45, 52, and 58; cervical, vulvar, vaginal, and anal precancerous or dysplastic lesions caused by HPV Types 6, 11, 16, 18, 31, 33, 45, 52, and 58; and genital warts caused by HPV Types 6 and 11.~GARDASIL 9 is indicated in males 9 through 45 years of age for the prevention of anal, oropharyngeal and other head and neck cancers caused by HPV Types 16, 18, 31, 33, 45, 52, and 58; anal precancerous or dysplastic lesions caused by HPV Types 6, 11, 16, 18, 31, 33, 45, 52, and 58; and genital warts caused by HPV Types 6 and 11.
Study: NCT05572632

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COPD Wellness
Description: COPD Wellness consists of 10 weekly sessions led by the COPD Wellness Coach. The intervention was designed to be portable, rely on little equipment, and require limited space (\~300sqft). The curriculum was iteratively developed with patient input and builds behavioral capability and self-efficacy through 30 minutes blocks of disease education and self-management skill building, exercise training, and social support.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COPD Wellness Plus+
Description: Couples COPD Wellness with the ZSFG Health Advocates Program. The HA will help the participant prioritize identified needs and, using an algorithm informed approach to connect the individual to the needed resource, this includes providing referrals to outside social or legal service agencies, help with applications for social benefits, or other services. The HA will use a checklist to track activities including review and prioritization of needs, referrals or resources provided, and contacts/contact attempts.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Includes access to comprehensive primary care services that is standardized across the SFHN. Participants randomized to the usual care arm will be offered referral to the Better Breathing Program that is part of SFHN standard care for COPD. At end of study enrollment, usual care participants will be offered the COPD Wellness intervention.
Study: NCT06541080

Intervention type: DIAGNOSTIC_TEST
Intervention: Shallow Whole Genome Sequencing (sWGS)-GIPXplore
Description: GIPXplore will be used to mine shallow whole genome sequencing cell free DNA data for identification of signatures.

Intervention type: DIAGNOSTIC_TEST
Intervention: Shallow Whole Genome Sequencing (sWGS)-GIPXplore
Description: GIPXplore will be used to mine shallow whole genome sequencing cell free DNA data for identification of signatures.

Intervention type: DIAGNOSTIC_TEST
Intervention: methylation-sensitive restriction enzymes (MSRE)-Single-molecule molecular inversion probes (smMIP)-seq assay
Description: Aberrant methylation in ccfDNA will be analyzed using the novel, highly sensitive MSRE-smMIP-seq technology.

Intervention type: DIAGNOSTIC_TEST
Intervention: methylation-sensitive restriction enzymes (MSRE)-Single-molecule molecular inversion probes (smMIP)-seq assay
Description: Aberrant methylation in ccfDNA will be analyzed using the novel, highly sensitive MSRE-smMIP-seq technology.
Study: NCT04961580

Intervention type: DRUG
Intervention: Ceftazidime Avitbatan Sodium
Description: For 6-18 years children, 62.5 mg/kg/once，q8h ; 3-6 months of age 50 mg/kg/ once,q8h, intravenous administration for 2 hours, daily dose is not more than 2.5g, children will be administrated at least five times.
Study: NCT05973656

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Alcohol dose given orally that will result in a 0.03% blood alcohol concentration (BAC).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo saliva, mouthwash, and cheek brush collection
Study: NCT05786586

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 650 nm low-level red-light
Description: 650 nm low-level red-light is a kind of laser, concentrated into a beam, to repeatedly irradiate the retina
Study: NCT06330818

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MRI
Description: Patients will get special MRI sequences (CO2-triggered BOLD MRI, Vessel-wall imaging, resting state BOLD MRI) to identify cerebral vasoreactivity and disease activity.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: H2 15O PET/CT
Description: Patients will get H2 15O PET/CT with acetazolamide challenge to define the cerebral vasoreserve for comparison with fMRI Images

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biosampling
Description: Patients do get a venous puncture for blood analysis on circulating endothelial cells and virus PCR analysis
Study: NCT05468567

Intervention type: DIAGNOSTIC_TEST
Intervention: SPHERE protocol : Spatial hearing performances test
Description: Participants will be instructed to localize a sound emitted in their environment using a virtual reality setup (SPHEAR protocol).

Intervention type: DIAGNOSTIC_TEST
Intervention: SPHERE protocol : Spatial hearing performances test
Description: Participants will be instructed to localize a sound emitted in their environment using a virtual reality setup (SPHEAR protocol).

Intervention type: DIAGNOSTIC_TEST
Intervention: French Matrix Test : audiology test of speech in noise perception
Description: Intelligibility threshold is the signal-to-noise ratio (in decibels) for which the subject can repeat 50% of the words heard in a dichotic listening.

Intervention type: DIAGNOSTIC_TEST
Intervention: French Matrix Test : audiology test of speech in noise perception
Description: Intelligibility threshold is the signal-to-noise ratio (in decibels) for which the subject can repeat 50% of the words heard in a dichotic listening.

Intervention type: BEHAVIORAL
Intervention: SSQ15 questionnaire of life : (The Speech, Spatial and Other Qualities of Hearing Scale)
Description: The SSQ questionnaire is a clinical subjective scale that allows evaluating of hearing performances in daily life. The questionnaire is divided into 3 main items (A: speech; B: spatial hearing; C: other qualities of hearing) comprising questions with rating scores out of ten.

Intervention type: BEHAVIORAL
Intervention: SSQ15 questionnaire of life : (The Speech, Spatial and Other Qualities of Hearing Scale)
Description: The SSQ questionnaire is a clinical subjective scale that allows evaluating of hearing performances in daily life. The questionnaire is divided into 3 main items (A: speech; B: spatial hearing; C: other qualities of hearing) comprising questions with rating scores out of ten.
Study: NCT05697640

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vericiguat Oral Tablet
Description: The treatment period includes ten weeks of daily vericiguat or placebo intake (depending on randomization) and a 30-day follow-up period (no vericiguat/placebo intake).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vericiguat Oral Tablet
Description: The treatment period includes ten weeks of daily vericiguat or placebo intake (depending on randomization) and a 30-day follow-up period (no vericiguat/placebo intake).
Study: NCT06581640

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-T treatment
Description: Peripheral blood lymphocyte collection, PBMC separation, BCMA CAR-T cell preparation/storage, lymphodepletion chemotherapy pretreatment for the subject, and BCMA CAR-T cell infusion.
Study: NCT05932459

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide for Suspension 100mg
Description: Take it with 240ml water in fasted condition.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide for Suspension 100mg
Description: Take it with 240ml water in fasted condition.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide for Suspension 300mg
Description: Take it with water in fasted condition or after taking infant formula.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide for Suspension 300mg
Description: Take it with water in fasted condition or after taking infant formula.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide for Suspension 25mg
Description: Take it with 240ml water on an empty stomach.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide tablets 100mg
Description: Take it with 240ml water in fasted condition.
Study: NCT05962424

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Hydrochloride
Description: Ketamine is an FDA-approved dissociative anesthetic.