TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06122883

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evaluation the effectiveness of distraction in the reception area in the management of anxious pediatric patients during dental local anesthesia
Description: Buccal and palatal infiltration will be administrated with basic behavior guidance techniques while the dentist wearing conventional attire in the treatment room after meeting the child in the reception area while wearing the friendly attire.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evaluation the effectiveness of distraction in the treatment area in the management of anxious pediatric patients during dental local anesthesia
Description: Buccal and palatal infiltration will be administrated with basic behavior guidance techniques while the dentist wearing friendly attire in the treatment room after meeting the child in the reception area while wearing the conventional attire.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evaluation the effectiveness of distraction in both reception and treatment areas in the management of anxious pediatric patients during dental local anesthesia
Description: Buccal and palatal infiltration will be administrated with basic behavior guidance techniques while the dentist wearing friendly attire in the reception area and treatment room.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Evaluation of the effectiveness of basic behavior guidance techniques without using any type of distraction aids in the management of anxious pediatric patients during dental local anesthesia
Description: Buccal and palatal infiltration will be administrated with basic behavior guidance techniques while the dentist wearing conventional attire in the reception area and treatment room.
Study: NCT04909502

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EHP-101 25 mg OD
Description: 25 mg OD during the first 28 Days of the trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EHP-101 25 mg BID
Description: 25 mg BID during the first 28 Days of the trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EHP-101 50 mg OD
Description: After 28 Days of treatment with 25 mg OD, patients will escalate to 50 mg OD up to the end of the trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EHP-101 50 mg BID
Description: After 28 Days of treatment with 25 mg BID, patients will escalate to 50 mg BID up to the end of the trial
Study: NCT04330794

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NMFACT
Description: caries index

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: DMF index
Description: caries index chart to collect data about decayed missed filled teeth
Study: NCT04793997

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Microbiome spray
Description: Throat spray containing 3 beneficial lactobacilli strains

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo spray
Description: Throat spray
Study: NCT05182580

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Results utilized from autonomous AI diagnostic system for diabetic retinopathy and/or diabetic macular edema
Description: If patients receive a negative result they do not see the retina specialist
Study: NCT05265884

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kinesiotaping
Description: The tape is waterproof, porous, and adhesive. The width is 5 cm and thickness of 0.5 mm will be used in this study. This tape is with elastic core wrapped within cotton and capable of stretching up to 140-150%, applies heat-sensitive acrylic adhesive to avoid risk of latex allergy .The tape without medicinal properties is water resistant and can remain on the skin for 3 to 5 days. It will be applied two times per week for one month

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: traditional therapy intervention
Description: traditional treatment (ROM exercises, stretching exercises, and Deep friction message) 3 times per week for one month.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: traditional therapy intervention
Description: traditional treatment (ROM exercises, stretching exercises, and Deep friction message) 3 times per week for one month.
Study: NCT05210868

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM355
Description: 1. Dose Escalation Phase CM355 will be taken by patients and will be treated follow the 3+3 dose escalation scheme~2. Expansion Phase CM355 will be taken by patients and will assess the efficacy of CM355 in patients with specific histopathological Non-Hodgkin's Lymphoma, and the safety of drug
Study: NCT05999175

Intervention type: DEVICE
Group type: OTHER
Intervention: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.
Description: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.

Intervention type: DEVICE
Group type: OTHER
Intervention: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.
Description: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.

Intervention type: DEVICE
Group type: OTHER
Intervention: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.
Description: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.

Intervention type: DEVICE
Group type: OTHER
Intervention: the mint toothpaste and mouthwash are used with the scalar toothbrush 33 medium with antibacterial  Spazzolino tau-marin® 3 times a day after the main meals for 28 days.
Description: the mint toothpaste and mouthwash are used with the scalar toothbrush 33 medium with antibacterial  Spazzolino tau-marin® 3 times a day after the main meals for 28 days.

Intervention type: DEVICE
Group type: OTHER
Intervention: subjects of this group will use their routine oral hygiene products.
Description: subjects of this group will use their routine oral hygiene products.
Study: NCT06120920

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Assigned Interventions
Description: Conventional physical therapy consists of hot pack application and transcutaneous electric stimulation (TENS) and routine knee strengthening exercises in addition with core stability exercises in three sessions per week for 4 weeks. Core stability exercises include bent knee hollow hold, bridging, supine toe tap and knee strengthening exercises include knee flexion strengthening exercises and knee extension isometric exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Assigned Interventions
Description: Conventional physical therapy consists of hot pack application and transcutaneous electric stimulation (TENS) and routine knee strengthening exercises in addition with core stability exercises in three sessions per week for 4 weeks. Core stability exercises include bent knee hollow hold, bridging, supine toe tap and knee strengthening exercises include knee flexion strengthening exercises and knee extension isometric exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy and Routine Knee Exercises with Hip Strengthening Exercises.
Description: Conventional physical therapy consists of hot pack application, Tens and routine knee exercise program same as group A and in addition with hip strengthening exercises. Hip strengthening exercises include hip flexion and extension strengthening exercises and hip internal rotation and external rotation and hip adduction and abduction strengthening exercises.C

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physical Therapy and Routine Knee Exercises with Hip Strengthening Exercises.
Description: Conventional physical therapy consists of hot pack application, Tens and routine knee exercise program same as group A and in addition with hip strengthening exercises. Hip strengthening exercises include hip flexion and extension strengthening exercises and hip internal rotation and external rotation and hip adduction and abduction strengthening exercises.C
Study: NCT05944861

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined ultrasonography and flouroscopy guided injeciton
Description: In the ultrasound+fluoroscopy group, the sacroiliac injection will be started under ultrasound guidance. With the help of ultrasound, when sacral 2 foramen is seen the needle will be advanced to the entrance of the sacroiliac joint under real-time in-plane view. After considering intra-articular placement, fluoroscopy guidance will be initiated. An anteroposterior image will be taken to confirm whether contrast material is within the joint. If intra-articular placement is not achieved after contrast medium infiltration, needle reposition will be performed under fluoroscopy for correct needle placement. After the intraarticular contrast pattern is seen, 1 ml of 40 mg methylprednisolone + 1 ml of 1% lidocaine mixture will be injected.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Flouroscopy guided injection
Description: In the fluoroscopy group, the advancement of the needle into the sacroiliac joint will be performed by taking anteroposterior and lateral views. In the same way, the needle tip will be placed in the inferior of the sacroiliac joint, and contrast material distribution examination and injection of the drug will be performed as in the ultrasound + fluoroscopy group.
Study: NCT04367103

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: prophylaxis for hypotension

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Phenylephrine
Description: standerd prophylaxis for hypotension
Study: NCT05063747

Intervention type: OTHER
Intervention: No intervention.
Description: Observational study. No intervention.
Study: NCT05011214

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: All patients received 0.01 mg/kg atropine and 1ug/kg dexmedetomidine iv as premedication.5% sevoflurane(FIO2=100%, 3L·min-1) was used to induce anaesthesia by mask inhalation and 3-4 % sevoflurane (adjusted according to the depth of the anaesthesia,FIO2=100%, 2L·min-1) was maintained

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: All patients received 0.1 mg/kg atropine and 1ug/kg dexmedetomidine iv as premedication.0.5mg·kg-1 esketamine was administered by vein in one minute, and 0.25mg·kg-1 esketamine was given at the beginning of the surgery.
Study: NCT06352593

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraoperative Dexmedetomidine
Description: Patients will be administered DEX 0.5 μg/kg for 10 min and then 0.4 μg/kg/h adjusted to 0.2-0.6 μg/kg/h.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive normal saline.
Study: NCT05873179

Intervention type: OTHER
Intervention: role-playing for learning the clinical interview
Description: role-playing for learning the clinical interview
Study: NCT04975737

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GamTBvac
Description: The subunit recombinant tuberculosis vaccine GamTBvac (lyophilisate for preparation of solution for subcutaneous administration, 5.35 mg / dose)

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo for subcutaneous administration
Study: NCT05063747

Intervention type: OTHER
Intervention: No intervention.
Description: Observational study. No intervention.

Intervention type: OTHER
Intervention: No intervention.
Description: Observational study. No intervention.
Study: NCT05990543

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nelmastobart and Capecitabine
Description: Nelmastobart intravenously every 3 weeks until PD or discontinuation due to toxicity. Administered on Day 1 of each cycle.~Capecitabine is administered orally for two weeks followed by a one-week rest period
Study: NCT06200974

Intervention type: RADIATION
Intervention: High dose rate prostate brachytherapy
Description: Temporary implantation of radioactive material into the prostate in the form of a stepping source of Iridium 192 that travels through 16-18 needles or catheters strategically placed through the prostate.
Study: NCT06496438

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Psychobiotics
Description: Dietary Supplement: A four probiotic regime, containing Lactobacillus rhamnosus, Bifidobacterium animalis subsp. lactis, Bifidobacterium breve, and Bifidobacterium longum at a concentration of 1, 000,000,000 CFU.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo regime, containing powdered glucose polymer, will be identical in packaging, appearance, consistency, and solubility in drinking water, thus making it impossible to recognize which are placebo and which the therapeutic formulation. Both will be identically standardized by the same pharmaceutical company \[Uni-Pharma, Greece\].
Study: NCT05736705

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic Submucosal Dissection
Description: Participants randomized in this arm will have the removal of their esophageal lesion utilizing the monopolar electrocautery knife.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endoscopic Submucosal Dissection
Description: Participants randomized in this arm will have the removal of their esophageal lesion utilizing the monopolar electrocautery knife.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bipolar electrocautery knife
Description: Participants randomized in this arm will have the removal of their esophageal lesion utilizing the bipolar electrocautery knife.
Study: NCT03990207

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PowerSpiral Enteroscopy System
Description: Motorized spiral enteroscopy system
Study: NCT04298866

Intervention type: OTHER
Group type: OTHER
Intervention: Experimental Arm
Description: * 3T MRI, maximum 1H30 long duration, including diffusion tensor imaging, susceptibility weighted imaging, multiparametric acquisitions, without contrast perfusion acquisitions.~* 7T MRI, maximum 1H30 long duration, including contrast enhanced acquisitions~* Neuropsychological battery including chronometric measures obtained through a computer interface
Study: NCT04774497

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxygen inhalation treatment group
Description: Oxygen inhalation group: oxygen inhalation was started on the first day of chemotherapy, and the oxygen inhalation volume was 2 L / min, 8 hours / day for 3 consecutive days.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: The control group was not given oxygen inhalation.
Study: NCT06093230

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide Tablets
Description: JT001 single dose, 0.3g

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide Tablets
Description: JT001 single dose, 0.3g

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deuremidevir Hydrobromide Tablets
Description: JT001 single dose, 0.3g
Study: NCT05114122

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vonlay Ceramic restorations
Description: vonlay is a hybrid of an onlay with an extended buccal veneer surface for use in bicuspid regions where there is mostly enamel to bond to. The vonlay is less invasive, more readily repairable, less technique-sensitive to attain adequate bonding, and will leave sounder tooth structure remaining if further treatment is required in the future

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Onlay Ceramic restorations
Description: Onlays are used to restore large areas of decay and also used to replace old restorations, whether they are defective amalgam fillings, old cast-gold onlays, or fabricated from some other material
Study: NCT05622266

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpotomy
Description: The patients who are randomly assigned to the experimental group receive pulpotomy.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Root Canal Therapy
Description: The patients who are randomly assigned to the Active Comparator group receive root canal therapy.
Study: NCT06507501

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low Load Blood Flow Restriction Exercise Training (LL-BFRE)
Description: Blood Flow Restriction exercise training, also known as occlusion training or KAATSU training, is a contemporary exercise training method based on partially restricting arterial and venous blood flow for short periods.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Load Resistive Exercise Training (HL-RE)
Description: HL-RE is a conventional, well known exercise method to enhance muscle strength and improve physical performance. It's performed by using resistance bands or weights applying on the extremity.
Study: NCT05104619

Intervention type: PROCEDURE
Intervention: tongue surgery
Description: In squamous cell carcinoma of the tongue, complete surgical resection of the tumor

Intervention type: PROCEDURE
Intervention: tongue surgery
Description: In squamous cell carcinoma of the tongue, complete surgical resection of the tumor
Study: NCT06036329

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Group A : provided with 1 Whitsundays Nasal mask without a spare mask cushion
Description: Group A will be provided with 1 Whitsundays Nasal mask without a spare mask cushion (replacement cushions will only be provided when requested)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Group B : provided with 1 Whitsundays Nasal mask with 2 spare mask cushions
Description: Group B will be provided with 1 Whitsundays Nasal mask with 2 spare mask cushions
Study: NCT05332249

Intervention type: PROCEDURE
Intervention: Surgery
Description: Patients who undergo spinal surgery for degenerative spinal disease

Intervention type: PROCEDURE
Intervention: Surgery
Description: Patients who undergo spinal surgery for degenerative spinal disease
Study: NCT05482581

Intervention type: OTHER
Intervention: Questionnaires set
Description: Participants will be asked to respond to the demographic information sheet,e-cigarette using characteristics sheet,awareness of e-cigarettes sheet;,willingness to use e-cigarettes sheet, knowledge, attitudes and cognitions related to e-cigarettes sheet, awareness of new regulations on e-cigarette control sheet.
Study: NCT05879367

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eflornithine (Dose Level 1)
Description: Eflornithine 2.3 g/m2 administered orally every 8 hours on a 2 weeks on, 2 weeks off schedule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eflornithine (Dose Level 2)
Description: Eflornithine 2.8 g/m2 administered orally every 8 hours on a 2 weeks on, 2 weeks off schedule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eflornithine (Dose Level -1)
Description: Eflornithine 1.75 g/m2 administered orally every 8 hours on a 2 weeks on, 2 weeks off schedule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide 150 mg/m2 (with option to escalate per USPI maintenance phase instructions) administered orally once daily on a 5 days on, 23 days off schedule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide 150 mg/m2 (with option to escalate per USPI maintenance phase instructions) administered orally once daily on a 5 days on, 23 days off schedule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide 150 mg/m2 (with option to escalate per USPI maintenance phase instructions) administered orally once daily on a 5 days on, 23 days off schedule
Study: NCT05615194

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: 0.6 mcg/kg in infusion over 10 minutes

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Volume equivalent in infusion over 10 minutes
Study: NCT05483166

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ImPACT
Description: During the ImPACT program, the childhood cancer survivor and at least one parent collaborates on:~1. Becoming aware of the child's core strengths and difficulties~2. Helping the child to be optimally responsive to the guidance of the parent(s), and~3. Creating compensatory strategies to respond to real-world manifestations of the child's difficulties and helping the child implement these strategies at home.
Study: NCT06277232

Intervention type: OTHER
Group type: OTHER
Intervention: Nutrition care
Description: Nutrition care is designed to include nutrition assessment (e.g., malnutrition screening, monitoring weight changes, etc.), optimization of individual dietary patterns, and evaluation. Through the Diet4painrelief platform, a dietician will follow up the progress of each participant in different timepoints and also plan meetings with other professionals in IPRP. A dietitian together with a physician in rehabilitation are responsible for the administration of the procedure.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Dialogue and education (part of Interdisciplinary Pain Rehabilitation Program)
Description: Dialogue and education consists of patient education, training in wellness and healthy living habits, meetings with families, video feedback, and couples therapy and self-training (e.g., home lessons, activity diary, physical self-training, reflection time, and self-analysis. . In addition, lectures in basic pain science and pain management are offered for both patients as well as for relatives, friends, and colleagues.
Study: NCT06103318

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ICOgnition
Description: The ICOgnition intervention for breast cancer patients consists of three levels:~Level 1: Monthly assessments using FACT-Cog PCI and Cognifit. Scores \<54 (PCI) or ≤250 (Cognifit) escalate to Level 2.~Level 2: Specialized content includes Cognitive Psychoeducation, validating experiences and improving health literacy; Behavioral Guidance, offering practical strategies for daily tasks; and Embracing Cognitive Deficits, promoting self-compassion and acceptance through mindfulness and metaphors.~Level 3: Online cognitive training focuses on enhancing cognitive skills through gaming exercises, completing the comprehensive intervention approach.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ICOgnition
Description: The ICOgnition intervention for breast cancer patients consists of three levels:~Level 1: Monthly assessments using FACT-Cog PCI and Cognifit. Scores \<54 (PCI) or ≤250 (Cognifit) escalate to Level 2.~Level 2: Specialized content includes Cognitive Psychoeducation, validating experiences and improving health literacy; Behavioral Guidance, offering practical strategies for daily tasks; and Embracing Cognitive Deficits, promoting self-compassion and acceptance through mindfulness and metaphors.~Level 3: Online cognitive training focuses on enhancing cognitive skills through gaming exercises, completing the comprehensive intervention approach.