TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04949269

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deucravacitinib
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deucravacitinib
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famotidine
Description: Specified dose on specified days
Study: NCT06304688

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yoga and Mediterranean Diet intervention
Description: It will last 12 weeks with a frequency of 2 sessions per week and each lasting 50 minutes.~* Warm-up phase (10 minutes): Conscious and gentle breathing. Gentle movements of the neck, shoulders, arms and legs to increase blood circulation and flexibility.~* Training phase (30 minutes): Series of gentle postures adapted to the needs of older adults. Includes standing, sitting and lying postures for relaxation and stretching. It will begin with basic postures and breathing techniques and will gradually advance as participants gain confidence.~* Return to calm (10 minutes): Deep relaxation in a lying position to integrate the benefits of the practice and promote total relaxation of the body and mind.~The Mediterranean diet consisted of: i) carbohydrates constitute 50% of the daily intake; ii) fats represented 35%; and iii) proteins represented 15%.
Study: NCT06086106

Intervention type: PROCEDURE
Intervention: Dorsal Penile Nerve Block DPNB
Description: DPNB is A type of pain control post-operative, often performed as a circumferential infiltration of the root of the penis (ring block). Two skin wheals are raised at the dorsal base of the penis, one on each side just below and medial to the pubic spine. A 25-gauge, 37.5-mm needle is introduced on each side, and the bupivacaine (1 to 1.5 mL) maximum dose 2 ml concentration 0.25% for infants is injected superficially and deep along the lower border of the pubic ramus to anesthetize the dorsal nerve. For a complete ring of infiltration,

Intervention type: DRUG
Intervention: Systemic opioids
Description: Systemic opioids belong to a class of analgesics, they act by attaching to opioid receptors in the brain and spinal cord. For relief of pain, they are frequently utilized in a variety of surgical procedures and can be given intravenously, and in intramuscular injections. Although opioids are considered highly effective in pain control, they can lead to several adverse effects, such as nausea, vertigo, and respiratory depression, some of which can be dangerous.
Study: NCT04734717

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Neurology test
Description: movement examination of patients with covid19 disease

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Neurology test
Description: movement examination of patients with covid19 disease
Study: NCT04662359

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Ultrasound Assessment
Description: Patients will undergo an ultrasound scan to assess the severity of their rheumatoid arthritis.
Study: NCT06408571

Intervention type: OTHER
Intervention: etiology
Description: As an important part of systems biology, metabolomics mainly detects various metabolites in the sample. Different from nucleic acids, proteins and other biological macromolecules, the relative molecular weight of these metabolites is small, generally within 1000Da, such as amino acids, carboxylic acids, carbohydrates, alcohols, amines, lipids and other special substances. Through qualitative and quantitative analysis of all endogenous low molecular weight metabolites before and after pathophysiology or gene modification stimulation, metabolomics reveals the essential characteristics of life activities and metabolism of the body, and provides guidance for exploring the pathogenesis, early diagnosis, treatment and prognosis of diseases.
Study: NCT05960981

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online-delivered Group-based Parent Mediated Intervention for Young Children with ASD
Description: The program consists of eight weekly 2-hour group sessions, with each group consisting of 8 to 10 families. During the sessions, supervisors present the strategies to the parents and explain how to integrate them into their interactions with their children. Sample videos are shown to illustrate the strategies, and group discussions allow parents to discuss their application. In the second half of each session, the parents' recorded videos are watched, and supervisors provide feedback on whether the strategies were accurately implemented. At the end of each session, supervisors address any questions the parents may have.
Study: NCT06261593

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood flow restriction
Description: The intervention protocol through blood flow restriction in patients with hemophilic arthropathy will consist of performing two exercises: heel elevation and ankle dorsiflexion in a closed kinetic chain. Both exercises will be performed for 5-10 minutes, performing 4 series (30, 15, 15, 15 repetitions) with 30 seconds of rest between series
Study: NCT06211309

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: co.mouthwas
Description: 15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Kin
Description: 15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Distilled water
Description: 15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Study: NCT05555745

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Audio-based behavioral activation intervention
Description: Access to audio-based behavioral activation intervention

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Audio-based self-monitoring intervention
Description: Access to audio-based self-monitoring intervention
Study: NCT06578078

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Zirconium Cyclosilicate
Description: Use of sodium zirconium cyclosilicate to optimize RAASi therapy, through up-titration of ACEi, ARB, ARNI or MRA therapy according to clinical guidelines

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care treatment (RAASi therapy)
Description: Standard of care treatment (RAASi therapy) without use of sodium zirconium cyclosilicate
Study: NCT04298398

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based-Cognitive Therapy (MBCT)
Description: MBCT is a program developed by Zindel Segal, Mark Williams and John Teasdale. During MBCT patients learn to decenter their negative thoughts and feelings, allowing the mind to move from an automatic thought pattern to conscious emotional processing. Mindfulness practices included in this program are breath awareness, body scan, sitting and walking meditation, and mindful yoga. The intervention will have the following structure: 8 weekly face-to-face meetings of 2 hours in a group format, daily home-based practice of learned skills, 4 hours of retreat/intensive group work after the fifth week, 6 months of home practice, 4 monthly consolidation face-to-face sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Focused Therapy Group for Cancer Recovery (EFT-CR)
Description: EFT-CR is an evidence-based approach to psychotherapy, which combines aspects of person-centered, gestalt and existential therapies with contemporary emotion theory and dialectical constructivism (Elliott et al, 2004, Rice \& Greenberg, 1984). On EFT-CR, therapist follows the client experience and guides the process, proposing therapeutic tasks when specific client behaviors occur. EFT-CR uses a set of emotion change principles which guide a process of emotional deepening process, from undifferentiated distress to secondary reactive emotions to primary maladaptive emotions to core pain and thence to primary adaptive emotions and emotional transformation (Elliott \& Greenberg 2016). The intervention will have the following structure: 8 weekly face-to-face meetings of 2 hours in a group format, daily home-based practice of learned skills, 4 hours of retreat/intensive group work after the fifth week, 6 months of home practice, 4 monthly consolidation face-to-face sessions.

Intervention type: OTHER
Group type: OTHER
Intervention: Treatment as usual (no intervention)
Description: Treatment as Usual is the condition in which participants will follow the usual institutional intervention protocol for medical follow-up and identification, referral and intervention for people identified with significant distress difficulties.
Study: NCT04521881

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tranexamic Acid 500 MG
Description: given once as an intramuscular injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tranexamic Acid 500 MG
Description: given once as an intramuscular injection
Study: NCT05362071

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote Exercise Group
Description: The intervention will have a weekly frequency of two sessions on non-consecutive days during the first six weeks and three sessions on non-consecutive days for the remaining six weeks. The exercise intervention will consist of four 3-week mesocycles. The session's structure will consist of a warm-up, the main part, in which a combined training program will be carried out, consisting of three distinct blocks, and at the end, stretching. Blocks 1 and 2 will consist of three strength exercises with bodyweight and alternative materials and aerobic training. Between blocks 1 and 2, and later in block 3, participants will take a free walk with displacement in the space they have available in their own home. The session will end with stretching exercises for the main muscle groups. The sessions will last 37 to 57 minutes over 12 weeks, with approximately 5 min of warm-up and stretching, and the main part ranging from 27 min to 47 min throughout the intervention.

Intervention type: OTHER
Group type: OTHER
Intervention: Group control
Description: Participants allocated to the GC will receive recommendations for the practice of physical activity based on information from three specific chapters of the Physical Activity Guide for the Brazilian Population (2021). The GC will receive through Whatsapp the information that is available in chapters 1, 4, and 5, which address the following topics: Understanding Physical Activity, Physical Activity for Adults, and Physical Activity for the Elderly. If sending via Whatsapp is not possible, the booklet will be printed and delivered to the participant. At the end of the 12 weeks, the same booklet will be made available to IG participants.
Study: NCT05878275

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent Informational Session
Description: Parents will receive a brochure on the importance of tummy time and limiting baby gear and watch a video on the importance of tummy time and limiting baby gear and receive support for implementing tummy time if requested.
Study: NCT05181553

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Canada's Food Guide principles (CFG diet)
Description: 28-day fully controlled dietary intervention during which participants will receive a diet that reflects the recommendations of Canada's Food Guide.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard North American diet (NAD diet)
Description: 28-day fully controlled dietary intervention during which participants will receive a diet that reflects the eating habits of Canadians.
Study: NCT06187402

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM-24C5
Description: Administered intravenously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM-24C5
Description: Administered intravenously
Study: NCT06261424

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IMPACT - rehabIlitation prograM for sPAstiC aTaxias
Description: The rehabilitation program will last 12 weeks and consists of three training sessions of 60 minutes per week (2 sessions in a therapy room and 1 session in an adapted pool with multiple levels of water) for a total of 36 sessions. Participants will be divided into 7 subgroups of 6 participants and each sub-group will be supervised by one physiotherapist (PT) and one physiotherapy technologist for safety considerations. It will focus on these three domains: 1) postural control; balance, trunk-limbs and multi-joints control and coordination and 3) functional mobility. Each domain contains a standardized list of exercises with different difficulty levels and specific times allocation. All exercises will be executed by the participants at each session at the appropriate difficulty level. The initial level of difficulty for each exercise will be determined by the PT based on individual results of the pre-intervention assessment and on individual performance, fatigue level and safety.
Study: NCT06443489

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-4849
Description: SHR-4849
Study: NCT04570293

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5% lidocaine medicated plaster
Description: The 5% lidocaine medicated plaster is measuring 10 cm x 14 cm contains 700 mg lidocaine (5% w/w) For each patient, the painful area and the trigger point will be chosen for treatment. The investigator will instruct the patient to replace the patch every 12 hours. The patches could be applied during the night (application in the evening and removal in the morning), or during the day. Patients will be told to apply up to three patches at one time.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: vehicle plaster
Description: Vehicle patches are identical to the active patch, except for the absence of lidocaine, without any optical differences.For each patient, the painful area and the trigger point will be chosen for treatment. The investigator will instruct the patient to replace the patch every 12 hours. The patches could be applied during the night (application in the evening and removal in the morning), or during the day. Patients will be told to apply up to three patches at one time.
Study: NCT04931901

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EMG TOF device
Description: Use of Stimpod NMX450X as an electromyographic neuromuscular monitor

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EMG TOF device
Description: Use of Stimpod NMX450X as an electromyographic neuromuscular monitor
Study: NCT05771545

Intervention type: OTHER
Intervention: Telepsychiatry
Description: Instead of coming to the hospital physically, the attending psychiatrist will evaluate the patient via a video-link.
Study: NCT05678335

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Hydroxychloroquine
Description: Oral hydroxychloroquine 200mg twice daily for 12weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Oral Tacrolimus 1-2mg twice daily for 12 weeks.
Study: NCT05583188

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aliya Pulsed Electric Fields (PEF) ablation
Description: Patients will undergo PEF ablation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab plus Platinum Doublet Chemotherapy
Description: If EGFR/ALK mutation negative, patients will receive standard of care dosing of three cycles of nivolumab at a dose of 360 mg every three weeks along with a platinum-based chemotherapy doublet (cisplatin or carboplatin plus pemetrexed for adenocarcinoma, cisplatin or carboplatin plus docetaxel, paclitaxel, or gemcitabine for squamous NSCLC) post-PEF ablation followed by resection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of care neoadjuvant therapy
Description: Patients not eligible for neoadjuvant nivolumab plus chemotherapy will receive standard of care systemic therapy post-PEF ablation followed by resection.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Surgical Resection
Description: Patients not eligible for systemic therapy will receive definitive surgery without neoadjuvant therapy as per institutional standard of care post-PEF ablation.
Study: NCT05379296

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Prevention Program Plus (DPP+)
Description: The DPP+ includes the CDC-approved DPP lifestyle program expanded to include a CDC-approved module on hypertension prevention and treatment

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diabetes Prevention Program (DPP)
Description: CDC-approved DPP lifestyle program
Study: NCT05604560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Patients will receive Tislelizumab (200 mg intravenous) on Day 1 of Cycles 1-6. Cycle 1 will be 14 days long and occur prior to surgery. Cycle 2 will be 14 days long and occur prior to standard of care chemotherapy. Cycles 3-6 will each be 21 days long and will be given after completion of standard of care chemotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SX-682
Description: Patients will receive SX-682 (200 mg twice daily by mouth) on Days 1-14 of Cycles 1-2 and Days 1-21 of Cycles 3-6. Cycle 1 will be 14 days long and occur prior to surgery. Cycle 2 will be 14 days long and occur prior to standard of care chemotherapy. Cycles 3-6 will each be 21 days long and will be given after completion of standard of care chemotherapy.
Study: NCT05313165

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LimFlow Stent Graft System
Description: Creation of an arteriovenous fistula in the desired limb location
Study: NCT05492058

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tactile stimulation group
Description: The tactile stimulation group will be asked to touch their own abdomen during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tactile stimulation group
Description: The tactile stimulation group will be asked to touch their own abdomen during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tactile stimulation group
Description: The tactile stimulation group will be asked to touch their own abdomen during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: listen music
Description: Pregnant women in the music group will listen to a song they want with headphones during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: listen music
Description: Pregnant women in the music group will listen to a song they want with headphones during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: listen music
Description: Pregnant women in the music group will listen to a song they want with headphones during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality group
Description: Pregnant women in the virtual reality group will be shown a nature walk video with nature sounds (stream, bird, etc.) during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality group
Description: Pregnant women in the virtual reality group will be shown a nature walk video with nature sounds (stream, bird, etc.) during the NST procedure.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality group
Description: Pregnant women in the virtual reality group will be shown a nature walk video with nature sounds (stream, bird, etc.) during the NST procedure.
Study: NCT05508022

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breathing exercise
Description: Before the enema is applied, breathing exercises will be applied to the participants in the intervention group.
Study: NCT04794270

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-Day for Astigmatism - TAM 24
Description: TEST

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-Day for Astigmatism - TAM 24
Description: TEST

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-Day for Astigmatism
Description: CONTROL

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-Day for Astigmatism
Description: CONTROL
Study: NCT03779659

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Synapse TENS device
Description: At the time of local anesthetic application the TENS device will be activated and placed on the buccal and lingual alveolar mucosa adjacent to the tooth receiving the restorative treatment using the pad applicator. The tip of the device with the electrodes are placed in a vertical up and down motion for approximately ten seconds. Following this, the level of pain and anxiety are measured using the Wong Baker Scale and Visual Analog Scale. The TENS device is used for achieving localized pain relief at the site of local anesthetic injection prior to injecting the anesthetic agent (such as lidocaine or articaine). Following this, once the clinician ensures that the patient is pain free then local anesthetic injection is given and following that the dental procedures are conducted.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical anesthetic gel
Description: The local anesthetic gel is typically used for achieving localized pain relief at the site of local anesthetic injection and this is part of standard care that is followed prior to dental procedures.~The amount of local anesthetic used will not exceed the maximum allowable dose, which will be calculated for each patient based on his/her age and weight prior to the dental procedure
Study: NCT05189912

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Specimen retrieving bag
Description: Specimen retrieving bag was used to retrieve resected polyps.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sucking polyps to the instrument channel port
Description: Remove the colonoscope suction valve and connect a polyp trap to suction onto the instrument channel port.
Study: NCT05927766

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: esophagogastroduodenoscopy
Description: patients with upper gastrointestinal symptoms will gone to upper endoscopy and biopsy when indicated

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: esophagogastroduodenoscopy
Description: patients with upper gastrointestinal symptoms will gone to upper endoscopy and biopsy when indicated
Study: NCT05347836

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA
Description: Determination of serum levels of sCD14 and sCD163 using ELISA

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA
Description: Determination of serum levels of sCD14 and sCD163 using ELISA
Study: NCT06037746

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Graston
Description: For the application, the individual was asked to lie face down, flex the knee to 90 degrees and release the ankle. The therapist took a position next to the individual on the side to be treated. Application was applied to the entire plantar fascia for 10 minutes in the longitudinal, vertical and oblique directions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Percussive massage
Description: For the application, the individual was asked to lie face down, flex the knee to 90 degrees and release the ankle. The therapist took a position next to the individual on the side to be treated. Application was applied to the entire plantar fascia for 5 minutes in all directions without being bound to a single direction.