TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05387707

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: difelikefalin 0.25 mg
Description: Oral difelikefalin 0.25 mg tablets administered twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: difelikefalin 0.5 mg
Description: Oral difelikefalin 0.5 mg tablets administered twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCS Cream
Description: TCS cream applied by study subjects to skin lesions once a day until control is achieved, then as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCS Cream
Description: TCS cream applied by study subjects to skin lesions once a day until control is achieved, then as needed

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TCS Cream
Description: TCS cream applied by study subjects to skin lesions once a day until control is achieved, then as needed

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Oral Placebo tablets administered twice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral Placebo tablets administered twice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: Vehicle Cream applied by study subjects to skin lesions once a day until control is achieved, then as needed
Study: NCT06288425

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis

Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis
Study: NCT06252909

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interpersonal Psychotherapy for Couples
Description: Interpersonal Psychotherapy for Couples (IPT-C) consists of 8 weekly conjoint sessions. The clinical goals are to promote resolution of the role dispute via renegotiation of role relations between the marriage partners and improve common mental disorders in the woman. Like Interpersonal Psychotherapy, IPT-C has an initiation phase (Session 1-2), middle phase (Sessions 3-6), and termination phase (Sessions 7-8).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Interpersonal Psychotherapy (Individual)
Description: Interpersonal Psychotherapy (IPT) is an evidence-based treatment to reduce depression and other common mental disorders. It focuses on helping patients resolve interpersonal problems of disagreements, loneliness, life changes, and grief, and/or change their orientation to the problem.
Study: NCT06391892

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neoadjuvant chemotherapy instead of upfront surgery
Description: All patients included into the study are recommended to go for upfront surgery (CT and CA19-9) by tumor board.~If preoperative ctDNA is positive, the investigators assume high risk for early recurrence (because of systemic tumor burden) and apply neoadjuvant chemotherapy at physicians choice instead.~* Apart from blood collection (within the scope of clinical routine), there is no additional diagnostic intervention performed on the patient.~* The respective neoadjuvant chemotherapeutical drug will be selected and applied by the treating medical oncologist at physicians choice (unaffected by study participation), usually mFOLFIRINOX or Gemcitabine/nabPaclitaxel at standardized dosage recommended by NCCN and local guidelines.~FOLFIRONOX: Folinic acid (also known as leucovorin), F - Fluorouracil (5-FU), IRIN - Irinotecan, OX - Oxaliplatin.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Upfront surgery
Description: Standard of care as recommended by tumor board (not affected by study conditions).
Study: NCT04726891

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.
Study: NCT04782661

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-70075200
Description: JNJ-70075200 solution or solid formulations will be administered orally.
Study: NCT04726891

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.
Study: NCT04782661

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-70075200
Description: JNJ-70075200 solution or solid formulations will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-70075200
Description: JNJ-70075200 solution or solid formulations will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo solution will be administered orally.
Study: NCT05214352

Intervention type: OTHER
Intervention: co-design in the intervention manual elaboration to increase the participation in the community
Description: It will co-design an intervention manual between all participants (families, young people with cerebral palsy and therapists) and researchers, using the involvement matrix to increase the participation of young people in the community.~Different focus grous will be created to work together and various online meetings, masterclass, workshops to increase the knowlodge in all groups.
Study: NCT05841290

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Master cone check
Description: Master cone check Clinically and confirmatory radiograph

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Master cone check
Description: Master cone check Clinically and confirmatory radiograph

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: application of resin based sealer inside the canal in the resin based sealer group
Description: application done by inserting inside the canal by spreader or master cone

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: application of resin based sealer inside the canal in the resin based sealer group
Description: application done by inserting inside the canal by spreader or master cone

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: application of the sillicon based sealer inside the canal in the sillicon based group
Description: application done by injection inside the canal

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: application of the sillicon based sealer inside the canal in the sillicon based group
Description: application done by injection inside the canal

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Obturation
Description: done by lateral condensation technique

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Obturation
Description: done by lateral condensation technique

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Visual Analogue Scale (VAS)
Description: Pain is evaluated using visual analogue scale (VAS) which is a pain rating scale. Scores are based on measures that are self-reported of symptoms that are recorded through a single handwritten mark placed at one point along the length of a 10-cm line representing a continuum between the two ends of the scale; on the left end of the scale (0 cm) means no pain and the on the right end of the scale (10 cm) worst pain

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Visual Analogue Scale (VAS)
Description: Pain is evaluated using visual analogue scale (VAS) which is a pain rating scale. Scores are based on measures that are self-reported of symptoms that are recorded through a single handwritten mark placed at one point along the length of a 10-cm line representing a continuum between the two ends of the scale; on the left end of the scale (0 cm) means no pain and the on the right end of the scale (10 cm) worst pain
Study: NCT05982730

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sensory-Augmented Postural Training
Description: To examine the safety and efficacy of postural training emphasized on the integration of multiple sensory information into motor control and to assess the effectiveness of postural training using Segway
Study: NCT05142371

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Continue current activities of daily living

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Intervention
Description: Participate in exercise intervention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Complete questionnaires

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study: NCT05215769

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education
Description: Participate in a video intervention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study: NCT05495984

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ERPs with electroencephalography (EEG)
Description: E-Prime 2.0 software will present visual and auditory stimuli in an experimental paradigm lasting approximately 30 minutes (ERPs). Visual stimuli will include photographs of color photographs of unfamiliar infants (aged 5- 10 months) balanced for ethnicity (Black/White) and gender (male/female) displaying happy neutral, and sad affective expressions. Auditory stimuli will include 2-second audio clips of high-distress and low-distress infant cries. Experimental procedure: Trials will consist of a central fixation cross (jittered 400-600ms), stimulus presentation (500ms faces, 2000ms cries), and blank screen (1000ms). Continuous electroencephalography (EEG) will be recorded using Net Station 4.2.1. A 128 Ag/Silver Chloride (AgCl) electrode net will be soaked in a warm potassium chloride solution, and net electrodes will be spaced evenly and symmetrically on each participant's head to cover the scalp.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ERPs with electroencephalography (EEG)
Description: E-Prime 2.0 software will present visual and auditory stimuli in an experimental paradigm lasting approximately 30 minutes (ERPs). Visual stimuli will include photographs of color photographs of unfamiliar infants (aged 5- 10 months) balanced for ethnicity (Black/White) and gender (male/female) displaying happy neutral, and sad affective expressions. Auditory stimuli will include 2-second audio clips of high-distress and low-distress infant cries. Experimental procedure: Trials will consist of a central fixation cross (jittered 400-600ms), stimulus presentation (500ms faces, 2000ms cries), and blank screen (1000ms). Continuous electroencephalography (EEG) will be recorded using Net Station 4.2.1. A 128 Ag/Silver Chloride (AgCl) electrode net will be soaked in a warm potassium chloride solution, and net electrodes will be spaced evenly and symmetrically on each participant's head to cover the scalp.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MIO
Description: A 12-week, manualized, individual parenting psychotherapy developed specifically for mothers with addictions administered by the Principal Investigator. It is designed to foster a mother's capacity for mentalization or reflective functioning (RF). MIO is offered in conjunction with standard addiction treatment.
Study: NCT05376852

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: based decitabine and olverembatinib（HQP1351)chemotherapy
Description: AP-CML treated with decitabine 10mg/m2 d1-5 intravenously (IV) over 60 minutes on days 1-5 and HQP1351 40mg qod every 28 days.After completion of HQP1351 lead-in, patients will receive HQP1351 PO qod on days 1-28 of subsequent cycles.~BC-CML:treated with decitabine 20mg/m2 d1-5 IV on days 1-5 and HQP1351 40mg qod every 28 days,with or without other chemotherapy Drugs
Study: NCT05003063

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Donepzil
Description: Test
Study: NCT06455722

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-P15-041
Description: Intravenous injection of one dose of 111-148 MBq (3-4 mCi) \[68Ga\]Ga-P15-041. Tracer doses of \[68Ga\]Ga-P15-041 will be used to image lesions by PET/CT.
Study: NCT05003063

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: Test
Study: NCT05056610

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: food antigens on duodenal mucosa
Description: Administration of food antigens on duodenal mucosa and determining the response through confocal laser endomicroscopy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: food antigens on duodenal mucosa
Description: Administration of food antigens on duodenal mucosa and determining the response through confocal laser endomicroscopy
Study: NCT04689763

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Training
Description: The programs contain sequential cognitive and exercise training, health lectures, and groups of daily living participation. We plan to assess the participants before and after the intervention programs. We expect that elders receiving training will improve on outcome measures. The results of the study will provide evidence of interventions for elderly with cognitive decline.
Study: NCT05435339

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GEN1053
Description: GEN1053 will be administered as an intravenous (IV) infusion every 3rd week. The dose levels will be determined by the starting dose and the escalation steps taken in the trial.
Study: NCT05240638

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TD Drainage
Description: Image-guided percutaneous cannulation of the TD and drainage with an endovascular catheter (microcatheter)
Study: NCT04340492

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education to Adapted Physical Activity
Description: 4 group sessions (5 patients) aiming at promoting physical activity, the first three focusing respectively on endurance, posture and balance and power re-enforcement at one-week interval. A fourth session, 3 months latter is a consolidating session aiming at identify and overcome obstacles to practice physical activity in everyday life.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard care
Description: Standard care concerning Parkinson's disease and physical activity
Study: NCT05647499

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Back 2 School program for problematic school absenteeism
Description: We will use the Danish version of the revised manual developed within the B2S study in Aarhus, Denmark. The B2S program consists of a 3 to 3,5 -hour initial clinical assessment, a clinical conference, 11 sessions where the youth and/or parent are attending, and a booster session after three months including youth and parent. The B2S manual comprise four school meetings with the child, parents, school staff and therapists present. In the Norwegian pilot study, we will add an extended school module to the B2S-program. The school module includes a pre-meeting interview with the schools in week 1 and session 1 with the school in week 2 or 3. The B2S counselor and the school will decide whether there is a need for an additional meeting between school meetings 1 and 2. There is also a booster session with the child, parents, the school and the B2S team 3 months after the program.
Study: NCT06353815

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 4% articaine infiltration
Description: Two injections using short needle and dental syringe will be given , the first injection is 1.5 ml out of 1.8 ml of 4% articaine with 1:100,000 epinephrine (ARTINIBSA 4% 1:100,000) in the mucobuccal fold adjacent to the mandibular first Molar, the second injection is 0.3 ml in the lingual side for lingual soft and hard tissues .

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 4% articaine infiltration
Description: Two injections using short needle and dental syringe will be given , the first injection is 1.5 ml out of 1.8 ml of 4% articaine with 1:100,000 epinephrine (ARTINIBSA 4% 1:100,000) in the mucobuccal fold adjacent to the mandibular first Molar, the second injection is 0.3 ml in the lingual side for lingual soft and hard tissues .
Study: NCT06263595

Intervention type: DEVICE
Intervention: gastric antral sonography
Description: Participant will undergo gastric antrum ultrasound and be scanned in the supine position followed by the right lateral decubitus position. Qualitative and quantitative assessments will be completed.

Intervention type: DEVICE
Intervention: gastric antral sonography
Description: Participant will undergo gastric antrum ultrasound and be scanned in the supine position followed by the right lateral decubitus position. Qualitative and quantitative assessments will be completed.
Study: NCT06012851

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Mobile behavioral parent training (mBPT)
Description: The mobile phone application includes behavioral parent training content (for example, praise, effective commands, reward systems) delivered in videos, examples, and quizzes that parents/caregivers access.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile behavioral parent training (mBPT)
Description: The mobile phone application includes behavioral parent training content (for example, praise, effective commands, reward systems) delivered in videos, examples, and quizzes that parents/caregivers access.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile behavioral parent training (mBPT)
Description: The mobile phone application includes behavioral parent training content (for example, praise, effective commands, reward systems) delivered in videos, examples, and quizzes that parents/caregivers access.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In the moment feedback
Description: In-the-moment feedback will include parenting feedback.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In the moment suggestions
Description: In-the-moment feedback will include suggestions for parenting strategies.
Study: NCT05023460

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Paresthesia-free (burst) ONS
Description: Stimulation intensity target of 60% of paresthesia threshold.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: ONS system deactivated
Study: NCT05373472

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 mRNA vaccine
Description: 2 doses of vaccine on Day 0 and Day 21

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 mRNA vaccine
Description: 2 doses of vaccine on Day 0 and Day 21

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 mRNA vaccine
Description: 2 doses of vaccine on Day 0 and Day 21

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 mRNA vaccine
Description: 2 doses of vaccine on Day 0 and Day 21

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 doses of placebo on Day 0 and Day 21
Study: NCT04782661

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo solution will be administered orally.