TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06288828

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic exercise + Nutrition consultant
Description: Participants in the intervention group will engage in 150 minutes of moderate aerobic exercise weekly for 16 weeks, primarily brisk walking or jogging.~For the initial four weeks, they will visit the hospital weekly for guidance and participate in home-based exercise following a protocol totaling 150 minutes of moderate aerobic exercise in the form of brisk walking or jogging. Healthcare professionals will help adjust exercise intensity based on heart rate (60-80% of maximum) and perceived exertion (RPE 12-15), while monitoring vital signs and adverse events.~After, they will transition to a home exercise program for twelve weeks, recording exercise details in a logbook. Weekly follow-up calls will ensure adherence and monitor adverse events.~They will be provided with nutritional recommendations by a dietitian, the same as the control group.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Nutrition consultant
Description: Participants will maintain their physical activity at the same level as before enrolling in the study.~However, they will be provided with nutritional recommendations by a dietitian, which include 1.2 grams of protein per kilogram of ideal body weight daily and a calorie intake of 35 kilocalories per kilogram of ideal body weight per day. To assess adherence and make necessary adjustments, participants will complete a 3-day food record at the beginning of the study, at week 8, and at the end of the study at week 16. If participants encounter difficulties adhering to the recommended nutritional intake, the dietitian will provide additional guidance to help them meet the requirements.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition consultant
Description: Participants will maintain their physical activity at the same level as before enrolling in the study.~However, they will be provided with nutritional recommendations by a dietitian, which include 1.2 grams of protein per kilogram of ideal body weight daily and a calorie intake of 35 kilocalories per kilogram of ideal body weight per day. To assess adherence and make necessary adjustments, participants will complete a 3-day food record at the beginning of the study, at week 8, and at the end of the study at week 16. If participants encounter difficulties adhering to the recommended nutritional intake, the dietitian will provide additional guidance to help them meet the requirements.
Study: NCT05892406

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Static guide
Description: A static guide will be designed and fabricated based on CBCT and intra-oral scan. Implant will be placed under the assistance of statistic guide through the whole procedure.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic navigation
Description: Implant will be placed under the assistance of dynamic navigation.
Study: NCT05672355

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: mRNA COVID-19 Vaccine
Description: Given IM

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Synthetic MVA-based SARS-CoV-2 Vaccine COH04S1
Description: Given IM
Study: NCT05077358

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intracorporeal anastomosis
Description: In this group, the anastomosis is performed inside the abdominal cavity with a laparoscopic technique. Specimen extraction will be done through Pfannenstiel incision or similar incision in lower abdomen.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extracorporeal anastomosis
Description: In this group, the anastomosis is performed by pulling out the bowel through a laparotomy.
Study: NCT05607329

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Secondary cytoreduction
Description: Open surgery is conducted by senior clinicians in gynecological oncology. Operation time，location and number of relapsed lesions, location and number of excised lesions, Whether achieved R0 or not, and other information are recorded.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: chemotherapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: chemotherapy
Study: NCT04751825

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: I-EAET
Description: See information in arm description.
Study: NCT06140446

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FeverApp
Description: The (self-management) FeverApp contains evidence-based information about fever and how to deal with it, tailored (phase-oriented) fever advices, and the option to monitor the health status of the child during a fever episode. All information and advices are based on the clinical expertise of paediatricians and the most recent international literature on fever, and complement the Dutch national fever guidelines. It is expected that by letting the body fight the infection on its own in a safe way, less ABs are needed, and the immune system will get stronger leading to less future infections as well.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DMT App
Description: The (self-care) DMT App is a decision making tool (DMT) that can be used by parents to choose a safe and effective herbal medicine (HM) product to reduce symptoms of mild, acute uncomplicated URTIs in their child. The advices that the DMT App provides, are based on a systematic review (SR) of SRs on effectiveness of HM for URTIs, a SR on working mechanisms of the most promising herbs, a prescription rates study of HM for URTIs in 6 European countries, and current EMA status of the included herbs. No prescription from a doctor is needed for these products.
Study: NCT05727826

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thrive MD-01 .
Description: The experimental group received a 60 Hz vibration stimulation treatment using the SMV method three times per week for two weeks (EG).
Study: NCT05972174

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5N8
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5N8
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5N8
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H7N9
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H7N9
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H7N9
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5 Only
Description: Sterile liquid for injection
Study: NCT06463301

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treadmill Training In CP child
Description: Treadmill training for children should be carefully tailored to their developmental level, physical ability, and specific therapeutic goals. Initial Sessions start with shorter sessions, around 5-10 minutes, especially for children with disabilities.~Progression will be made when the child becomes more accustomed to the treadmill. Aim for a total of 20-30 minutes per session, including breaks if necessary then then Start at a slow walking pace, approximately 0.5 to 1.0 miles per hour (mph) or 0.8 to 1.6 kilometers per hour (kph). Adjust the speed based on the child's comfort and ability to maintain a safe and effective walking pattern.~Older Children (8-12 years Begin with a walking pace of 1.0 to 1.5 mph (1.6 to 2.4 kph). Gradually increase the speed to a brisk walk or light jog, up to 2.0 to 3.0 mph (3.2 to 4.8 kph), depending on the child's progress and comfort level along with conventional physical therapy.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy
Description: conventional physical therapy session would typically include gentle stretching, joint mobilization, range of motion exercises for both the upper and lower body, gait training, and standing frame activities. Each component is designed to improve various aspects of physical function, ensuring a comprehensive approach to rehabilitation
Study: NCT05972174

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5 Only
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5 Only
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H7 Only
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H7 Only
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H7 Only
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5 Only-CG
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5 Only-CG
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1018 for H5 Only-CG
Description: Sterile liquid for injection
Study: NCT05652595

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GP40141
Description: Once, at a dose of 3 mcg/kg, Subcutaneously in the shoulder area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GP40141
Description: Once, at a dose of 3 mcg/kg, Subcutaneously in the shoulder area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nplate
Description: Once, at a dose of 3 mcg/kg, Subcutaneously in the shoulder area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nplate
Description: Once, at a dose of 3 mcg/kg, Subcutaneously in the shoulder area
Study: NCT05331807

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Omega-3 FA
Description: Two capsules of 1000mg fish oil daily (Each soft gel capsule contains 180mg EPA and 120 mg DHA)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: one capsule of vitamin D3 weekly (one D3 capsule contains 50,000 IU)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Combined Omega-3 and Vitamin D Supplementation
Description: Two capsules of 1000mg fish oil daily (Each soft gel capsule contains 180mg EPA and 120 mg DHA) and one capsule of vitamin D3 weekly (one D3 capsule contains 50,000 IU)
Study: NCT05406921

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MIND at Home
Description: Maximizing Independence at Home-MIND at Home (MIND) is a comprehensive care coordination program born from geriatric psychiatry. This model takes an interdisciplinary, collaborative care approach to care by systematically assessing and addressing a wide range of dementia-care related needs of both PLWD and their care partners that place both at increased risk for poor outcomes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MIND at Home
Description: Maximizing Independence at Home-MIND at Home (MIND) is a comprehensive care coordination program born from geriatric psychiatry. This model takes an interdisciplinary, collaborative care approach to care by systematically assessing and addressing a wide range of dementia-care related needs of both PLWD and their care partners that place both at increased risk for poor outcomes.
Study: NCT05280249

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: both aerobic and resistance exercises in the green exercise concept
Description: Green exercise is a type of exercise done outdoors. It is an advantageous type of exercise in benefiting from sunlight and reducing anxiety. Participants in this group will be given aerobic and resistance exercises in the open air.
Study: NCT05514249

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CRD-TMH-001
Description: Participant will receive a single dose of CRD-TMH-001 administered via intravenous injection.
Study: NCT05892406

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robotic system
Description: Implant will be placed under robotic arm and human collaboration.
Study: NCT04806360

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ACRF surgery
Description: A new surgical procedure that previously proposed by our team.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional anterior surgery
Description: Anterior cervical discectomy and fusion surgery or anterior cervical corpectomy and fusion surgery.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional posterior surgery
Description: Laminectomy and fusion surgery or laminoplasty surgery.
Study: NCT05538351

Intervention type: DEVICE
Intervention: Body Composition Monitor (BCM)
Description: The hydration status of each participant from the clinical assessment and the patient reported signs and symptoms will be compared with the readings from bioimpedance (BCM machine).
Study: NCT05147909

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Sodium Phosphate
Description: Sodium Phosphate 2 capsules daily (containing a total of 500 mg of Pi, 372mg of sodium)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Sodium Phosphate
Description: Sodium Phosphate 2 capsules daily (containing a total of 500 mg of Pi, 372mg of sodium)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Sodium Chloride
Description: Sodium Chloride 2 capsules daily (NaCl, containing a total of 372mg of sodium)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Sodium Chloride
Description: Sodium Chloride 2 capsules daily (NaCl, containing a total of 372mg of sodium)
Study: NCT05737212

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 9Gy-Eq
Description: Patients will be infused DMX-101 intravenously at a dose of 500mg/kg/hr over 3 hours. Thereafter, patient will receive neutron irradiation simultaneously for a certain period of time based on his Boronophenylalanine (BPA) concentration in the blood.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 11Gy-Eq
Description: Patients will be infused DMX-101 intravenously at a dose of 500mg/kg/hr over 3 hours. Thereafter, patient will receive neutron irradiation simultaneously for a certain period of time based on his Boronophenylalanine (BPA) concentration in the blood.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 13Gy-Eq
Description: Patients will be infused DMX-101 intravenously at a dose of 500mg/kg/hr over 3 hours. Thereafter, patient will receive neutron irradiation simultaneously for a certain period of time based on his Boronophenylalanine (BPA) concentration in the blood.
Study: NCT05353127

Intervention type: DIAGNOSTIC_TEST
Intervention: CPET/Cardiopulmonary Exercise Test
Description: During CPET, a patient exercises against a progressively increasing work rate until volitional exhaustion, while breath-by-breath respiratory gasses are analyzed.
Study: NCT05021731

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rifampicin plus Isoniazid
Description: Administration of rifampicin plus isoniazid for latent tuberculosis

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifapentine plus Isoniazid
Description: Administration of rifapentine plus isoniazid for latent tuberculosis

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifampicin alone
Description: Administration of rifampicin alone for latent tuberculosis
Study: NCT04652830

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Naprapathy training
Description: Active training aimed at strengthening the abdominal muscles

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: No change of daily routines in regard to training
Study: NCT05858437

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Sodium propionate
Description: The patients will be randomized to PA or placebo intervention (2:1 randomization).~After the intervention of 28 days, we conduct an open-label study phase, where all patients are offered a dietary supplement of PA for overall 12 weeks (8 additional weeks for the intervention group and 12 weeks for the placebo group).~By doing so we are giving every patient the opportunity to take PA and benefit from the possible positive impact on immunsystem and intestinal barrier function.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The patients will be randomized to PA or placebo intervention (2:1 randomization).~After the intervention of 28 days, we conduct an open-label study phase, where all patients are offered a dietary supplement of PA for overall 12 weeks (8 additional weeks for the intervention group and 12 weeks for the placebo group).~By doing so we are giving every patient the opportunity to take PA and benefit from the possible positive impact on immunsystem and intestinal barrier function.
Study: NCT04807400

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inclisiran
Description: Inclisiran Sodium 300mg on Day 1 and Day 90 by subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inclisiran
Description: Inclisiran Sodium 300mg on Day 1 and Day 90 by subcutaneous injection

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioural Support
Description: Regular telephone based behavioural support programme delivered throughout the study period, as measured by point of care testing device.
Study: NCT06463353

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: trilinolein cream group
Description: Apply trilinolein cream evenly to the affected skin twice daily. The dosage is calculated using Finger Tip Units (FTU) and should not exceed a maximum of 30 grams per day.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: cream base group
Description: Apply cream base evenly to the affected skin twice daily. The dosage is calculated using Finger Tip Units (FTU) and should not exceed a maximum of 30 grams per day.
Study: NCT04789694

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiological intervention
Description: * Rehabilitation specialist consultation (3x)~* Individualized home-based exercise plan~* Functional capacity measuring

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological intervention
Description: * Clinical psychologist consultation (3x)~* Anxiety and depression scoring~* Psychological support

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutritional intervention
Description: * Nutritional specialist consultation (3x)~* Malnutrition scoring~* Dietary supplementation
Study: NCT04911179

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vivfrail-Cog combined multicomponent physical exercise and cognitive stimulation.
Description: The areas to be worked on are: Attentional system: selective attention and concentration; alternating attention / dual attention; Processing speed; perceptual organization; working memory and cognitive flexibility; comprehension, abstraction and verbal reasoning, planning, execution, and problem solving.~Four programs have been developed stimulation different difficulty levels to adapt to the capabilities of each participant.
Study: NCT05110313

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TILDRAKIZUMAB
Description: ILUMYA (tildrakizumab-asmn) is a humanized IgG1/k monoclonal antibody that selectively binds to the p19 subunit of IL-23 and inhibits its interaction with the IL-23 receptor. IL-23 is a naturally occurring cytokine that is involved in inflammatory and immune responses.~ILUMYA injection for subcutaneous use is a sterile, clear to slightly opalescent, colorless to slightly yellow solution supplied in 1mL single-dose prefilled syringe which contains 100 mg of tildrakizumab-asmn formulated in: L-histidine (0.495 mg), L-histidine hydrochloride monohydrate (1.42 mg), polysorbate 80 (0.5 mg), sucrose (70.0 mg), and Water for Injection, USP with a pH of 5.7-6.3. ILUMYA is supplied in a single-dose prefilled syringe with a glass barrel and 29-gauge fixed, 1/2-inch needle.
Study: NCT04879394

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hypnosis
Description: 4 weekly hypnosis sessions, aiming at pain control and distress management. The 90 min. sessions will be conducted in group format by a doctorate-level psychologist trained in hypnosis. Contents will be detailed on hypnosis protocols to ensure standardization.
Study: NCT05757947

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Сoronary bypass surgery according to the I-graft method
Description: Revascularization of the right coronary artery basin will be performed using no-touch SVG and the formation of an anastomosis of the stump of the right internal mammary artery and end-to-end saphenous vein graft.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Сoronary bypass surgery by the method of free conduit
Description: Revascularization of the right coronary artery basin will be performed using no-touch SVG and anastomosis of the saphenous vein graft to aorta.
Study: NCT05266755

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fracture Territorial Liaison Service afert a Hip fracture
Description: Give a diferent than the current one way of follow up to the patients with hip fracture

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Fracture Territorial Liaison Service afert a Hip fracture
Description: Give a diferent than the current one way of follow up to the patients with hip fracture
Study: NCT05023187

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SCOT
Description: A 8-week social and cognitive online training to improve both cognitive and social functioning, which includes 2 sessions (\~45 minutes each) of individual cognitive training through the BrainHQ© program 2020 (BrainHQ© Posit Science) and a psycho-educational group session for each week (24 sessions in total).~In the experimental intervention, all activities are focused on enhancing executive functions (working memory, processing speed, inhibitory control etc.) and social cognition abilities (identifying/recognizing facial expressions, styles attribution, drawing conclusions etc.).