TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05846113

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Renasight
Description: The Renasight™ test is a next generation sequencing (NGS) gene mutation assay for patients with chronic kidney disease (CKD) which utilizes genomic DNA from patient blood or buccal swab samples to analyze over 380 genes that are associated with autosomal dominant, autosomal recessive and X-linked disorders.~Patients undergoing Renasight™ testing are offered optional genetic information sessions in addition to their test results.~RenasightTM is a commercially available Laboratory Developed Test (LDT) certified under the Clinical Laboratory Improvement Amendments (CLIA). This test has not been cleared or approved by the U.S. Food and Drug Administration (FDA).
Study: NCT05587413

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: periodontal care
Description: periodontal treatment
Study: NCT05977465

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 25 MG
Description: treatment
Study: NCT05629676

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BMT-VR
Description: BMT-VR is a novel psychosocial intervention that addresses the supportive care needs of patients undergoing BMT. BMT-VR includes six sections focused on: 1) psychoeducation to help patients increase their awareness to stress and challenges that may accompany the BMT journey; 2) supportive psychotherapy strategies to help patients adjust to the intense BMT hospitalization; 3) psychosocial skill building to promote mindfulness, acceptance and gratitude while living with uncertainty; 4) psychoeducation to manage expectations and enhance preparedness for extended hospitalization; 5) psychosocial skill-building to promote effective coping; and 6) an overview of psychosocial skills grounded in cognitive behavior therapy, mindfulness, and positive psychology
Study: NCT04861441

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aircast Cryo Cuff (Shoulder) and Aircast Cryo Cuff I/C Motorized Cooler
Description: Patient will wear the continuous cryo cuff for a designated period of time and will record their pain and narcotic use post operatively.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Icepacks
Description: Standard of care icepacks will be used postoperatively for designated amount of times and patients will record pain and narcotic use post operatively.
Study: NCT04748952

Intervention type: DEVICE
Intervention: Densah burs
Description: Osseodensification is a non-excavating implant site preparation technique. It creates a densified layer of surrounding bone through compaction autografting while simultaneously plastically expanding the bony ridge at the same time facilitating for placement of large diameter implants and also avoiding fenestration and dehiscence defects. The autografting occurs along the entire length of the osteotomy through a hydrodynamic process with the use of irrigation. The result is a consistently cylindrical and densified osteotomy.
Study: NCT06011096

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: skin-to-skin contact and delayed cord clamping
Description: Placental separation time, separation method, amount of postpartum bleeding and postpartum comfort were evaluated with skin-to-skin contact and late cord clamping after delivery.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: avoiding skin-to-skin contact and early cord clamping
Description: After delivery, placental separation time, separation method, amount of postpartum bleeding and postpartum comfort were evaluated without skin-to-skin contact and late cord clamping.
Study: NCT04940689

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg
Description: The patient will be anesthetized with Dexmedetomidine 0.5 g / kg + lidocaine 1.5 mg / kg for the induction instead of morphin.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remifentanil
Description: The patient will be anesthetized with morphin.
Study: NCT05681637

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing mixtures of O2 and N2 and monitoring SpO2 on each finger
Description: Volunteers sequentially inhale three hypoxic gas mixtures each for 2.5 minute. Every measurement will begin with a two-minute stabilization phase, during which the physiological values of the volunteer will be checked. During the experiment, non-invasive SpO2 measurements will be performed continuously on the individual fingers of volunteer hands throughout the experiment.
Study: NCT05653973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetylcholine
Description: acetylcholine, and acetylcholine + L-NAME (Nitric oxide synthase inhibitor) are locally and acutely delivered to the cutaneous microvasculature to assess endothelium- and nitric oxide-dependent dilation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Endothelin-1
Description: endothelin-1, endothelin-1 + BQ-788 (endothelin receptor type B-inhibitor), and endothelin-1 + BQ-123 (endothelin receptor type A-inhibitor) are locally and acutely delivered to the cutaneous microvasculature to assess endothelin-mediated constriction and the role of the receptor subtypes in this response.
Study: NCT04708483

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extra DCE-CT scan
Description: DCE-CT of thoracic tumors as an early biomarker for treatment monitoring in comparison with morphologic criteria.
Study: NCT05120154

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Online educational materials
Description: The CAPACITI program is comprised of three independent modules, taken separately (each constituting an intervention): (1) Identify and Assess; (2) Enhance Communication Skills; (3) Enhance Skills for Ongoing Care (including involvement of family and specialists). Each module addresses a critical component of implementing a palliative care approach into primary care practice. The CAPACITI program emphasizes practice supports in each module, integrating two components: 1) clinical education in the form of expert advice and tips, and 2) evidence-based tools with action steps.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online educational materials
Description: The CAPACITI program is comprised of three independent modules, taken separately (each constituting an intervention): (1) Identify and Assess; (2) Enhance Communication Skills; (3) Enhance Skills for Ongoing Care (including involvement of family and specialists). Each module addresses a critical component of implementing a palliative care approach into primary care practice. The CAPACITI program emphasizes practice supports in each module, integrating two components: 1) clinical education in the form of expert advice and tips, and 2) evidence-based tools with action steps.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Facilitated online webinars
Description: Intervention participants will be invited to participate in facilitated online discussions. These discussions review the online materials and share strategies for problem-solving.
Study: NCT05587452

Intervention type: DIAGNOSTIC_TEST
Intervention: Colonoscopy
Description: Colonoscopy is performed to identify whether the patient has colorectal adenoma or cancer

Intervention type: DIAGNOSTIC_TEST
Intervention: Colonoscopy
Description: Colonoscopy is performed to identify whether the patient has colorectal adenoma or cancer

Intervention type: DIAGNOSTIC_TEST
Intervention: Colonoscopy
Description: Colonoscopy is performed to identify whether the patient has colorectal adenoma or cancer

Intervention type: DIAGNOSTIC_TEST
Intervention: Test of ctDNA methylation
Description: A specified panel is used to detect the site of methylation of ctDNA in plasma

Intervention type: DIAGNOSTIC_TEST
Intervention: Test of ctDNA methylation
Description: A specified panel is used to detect the site of methylation of ctDNA in plasma

Intervention type: DIAGNOSTIC_TEST
Intervention: Test of ctDNA methylation
Description: A specified panel is used to detect the site of methylation of ctDNA in plasma

Intervention type: DIAGNOSTIC_TEST
Intervention: Test of characteristics of ctDNA fragment
Description: Low pass whole genome sequencing is used to detect the characteristics of ctDNA fragment

Intervention type: DIAGNOSTIC_TEST
Intervention: Test of characteristics of ctDNA fragment
Description: Low pass whole genome sequencing is used to detect the characteristics of ctDNA fragment

Intervention type: DIAGNOSTIC_TEST
Intervention: Test of characteristics of ctDNA fragment
Description: Low pass whole genome sequencing is used to detect the characteristics of ctDNA fragment
Study: NCT04702997

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bardoxolone methyl oral capsule
Description: Bardoxolone methyl capsules dose escalated from 5 mg to a maximum of 20 or 30 mg, depending on baseline proteinuria status

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral capsule
Description: Capsule containing an inert placebo
Study: NCT04965636

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mepolizumab
Description: Mepolizumab will be provided in pre-filled safety syringe
Study: NCT05706636

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: oral mini pulse
Description: 5mg / week oral dexamethasone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical cream
Description: topical fluticasone cream for body lesions and topical tacrolimus for face lesions

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical cream
Description: topical fluticasone cream for body lesions and topical tacrolimus for face lesions

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: targeted phototherapy
Description: twice weekly targeted excimer light sessions

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: targeted phototherapy
Description: twice weekly targeted excimer light sessions
Study: NCT06436495

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hair Wash Shampoo
Description: A standard marketed hair wash shampoo is to be used for the hair wash intervention post baseline evaluations of the scalp.
Study: NCT04243122

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 2.5 MG Oral Tablet [ELIQUIS]
Description: 2.5mg twice per day for 6 months Then treated \& followed up as per standard of care

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin 81 mg
Description: 81mg once per day for 6 months Then treated \& followed up as per standard of care
Study: NCT06360705

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: StrataMGT
Description: StrataMGT® is a semi-permeable, non-resorbable and self-drying gel. StrataMGT® contains no steroids, hormones, alcohol, parabens or fragrances. StrataMGT® gel is bacteriostatic, inert, and is manufactured in compliance with good manufacturing practices (GMPs), 21CFR210 and 211.
Study: NCT06393010

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: online rehabilitation program
Description: Participants in the research will undergo a three-week online rehabilitation program, three times a week, lasting 40-45 minutes each session. The program includes posture, stretching, joint range of motion, strengthening exercises, pain education, and discussions. Conducted via Zoom, only the practitioner will be present during sessions. Non-attendance for two consecutive sessions or failure to provide feedback will result in exclusion. Exercises cover various body areas and types, including posture correction, range of motion, stretching, isometric neck and shoulder exercises, stick exercises, and strengthening exercises.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: online rehabilitation program
Description: Participants in the research will undergo a three-week online rehabilitation program, three times a week, lasting 40-45 minutes each session. The program includes posture, stretching, joint range of motion, strengthening exercises, pain education, and discussions. Conducted via Zoom, only the practitioner will be present during sessions. Non-attendance for two consecutive sessions or failure to provide feedback will result in exclusion. Exercises cover various body areas and types, including posture correction, range of motion, stretching, isometric neck and shoulder exercises, stick exercises, and strengthening exercises.
Study: NCT02127736

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amitriptyline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Study: NCT05869877

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bundled
Description: An peripheral intravenous catheter will be inserted by an RN specially trained in PIVC placement, with or without ultrasound. Using best of class medical products, will evaluate dwell time and complications of the PIVC inserted using a bundled approach versus one inserted with the bundle
Study: NCT05799404

Intervention type: DIAGNOSTIC_TEST
Intervention: ultra-high resolution CT
Description: stapes footplate thickness measurement

Intervention type: DIAGNOSTIC_TEST
Intervention: ultra-high resolution CT
Description: stapes footplate thickness measurement

Intervention type: DIAGNOSTIC_TEST
Intervention: ultra-high resolution CT
Description: stapes footplate thickness measurement
Study: NCT05376293

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral Internet program
Description: The 12-week behavioral Internet program is designed to increase physical activity to recommended levels. Participants will be asked to plan and report aerobic exercise weekly, watch weekly video lessons, and complete brief weekly homework assignments.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Informational newsletter condition
Description: Newsletters will focus on the health benefits of regular physical activity, exercise safety, and will provide information on national exercise guidelines.
Study: NCT06171594

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Chlorhexidine mouthwash
Description: The proposed study is part of a PhD educational project and will be a double blind, randomised design, crossover trial for the effect of Chlorhexidine (CHX) mouthwash on healthy control and people with dental erosion (PwDE). This study aims to explore mouthwash's effect on oral microbiome recovery in WMS and salivary pellicle and its impact on blood pressure and arterial stiffness in healthy controls PwDE

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Chlorhexidine mouthwash
Description: The proposed study is part of a PhD educational project and will be a double blind, randomised design, crossover trial for the effect of Chlorhexidine (CHX) mouthwash on healthy control and people with dental erosion (PwDE). This study aims to explore mouthwash's effect on oral microbiome recovery in WMS and salivary pellicle and its impact on blood pressure and arterial stiffness in healthy controls PwDE
Study: NCT05666479

Intervention type: DEVICE
Intervention: Dexcom G6 Pro Continuous Glucose Monitor (CGM)
Description: A DexCom G6 CGM will be implanted on the subject's abdomen contralateral to the surgical site (i.e. left abdomen for right knee or right hip replacements) no less than 30 cm from the surgical site. This CGM shall be termed primary for study purposes. Subjects will wear the primary DexCom G6 CGM for the entirety of the following 10-day timeline: 3/4-days pre-operative, day of hip or knee replacement surgery, and 5/6-day postoperative recovery.~A second CGM will be implanted in subjects postoperatively while in the Post Anesthesia Care Unit (PACU). This CGM, termed secondary for study purposes, will be implanted immediately adjacent to the primary CGM. Subjects will wear the secondary DexCom CGM for the 7 days: day of hip or knee replacement surgery (postoperatively) and 5/6-day postoperative recovery.
Study: NCT05457114

Intervention type: DEVICE
Intervention: Pulmonary artery catheter (Edward Lifesciences, Irvine, California, USA)
Description: PAC was inserted and connected to a continuous cardiac output monitor (Vigilance I from 2006 to 2012; Vigilance II from 2012 to 2022, Edward Lifesciences, Irvine, USA)

Intervention type: DEVICE
Intervention: FloTrac Vigileo system (EV1000 clinical platform, Edward Lifesciences, Irvine, California, USA)
Description: Without PAC, monitoring with FloTrac Vigileo system (EV1000 clinical platform, Edward Lifesciences, Irvine, California, USA) was performed for continuous cardiac output monitoring.
Study: NCT05084599

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metaraminol 2.7μg/kg/min
Description: After spinal anesthesia, the patient was placed in a supine position until the fetus was delivered, and metaraminol was given at an initial rate of 2.7μg/kg/min throughout the process.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Metaraminol 2μg/kg/min
Description: After spinal anesthesia, the patient was placed in left-tilt position until the fetus was delivered, and metaraminol was given at an initial rate of 2μg/kg/min throughout the process.
Study: NCT05163210

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AO+VR
Description: The experimental treatment will consist of 15 hours (min. 15, max. 20), and will be carried out 4 days/week for a total duration of 5 weeks. During the rehabilitation sessions, the patient will be instructed to carefully watch videos lasting about 1.5 minutes, presented on Liquid Crystal Display (LCD) monitor, consisting in unimanual or bimanual actions performed by an actor, from a lateral perspective. Subsequently, the patient will be asked to imitate the actions presented for at least 3 consecutive times, within a time window of 3 min., using the same objects observed in the video, in a virtual scenario (VR), through the Khymeia Virtual Reality Rehabilitation System (VRRS).

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: CO+VR
Description: Patients of the control group will be required to observe videos depicting naturalistic scenes, without motor contents, for 1.5 min. Then, they will receive a motor training in the VR environment, performing the same type of exercises included in the above-described experimental treatment, prompted by the verbal instructions of an expert therapist. Thus, the general setting for carrying out the rehabilitation sessions will be identical to that of the experimental treatment, except for the fact that the control group will not be involved in action observation before preforming the exercises. Thus, the control treatment is not based on action imitation, but on purely motor execution.
Study: NCT05397210

Intervention type: DEVICE
Intervention: Infinity-Lock Button System
Description: Infinity-Lock Button System
Study: NCT05348668

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hybrid dose-fraction Radiotherapy combined with immune checkpoint inhibitors
Description: Hybrid dose-fraction Radiotherapy combined with immune checkpoint inhibitors
Study: NCT04853498

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3720
Description: This is an androgen receptor antagonists.
Study: NCT04862832

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music intervention
Description: The cold pressor test will consist in the immersion of the participants' arm in 10 degrees circulating water for two minutes.~The music sequences will be all 20 minutes, instrumental, professionally recorded in the studio and composed specifically for the Music Care application and are thus unfamiliar to participants. There will be two music conditions: the most-liked-music (MLM) and least-liked-music (LLM) conditions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music intervention
Description: The cold pressor test will consist in the immersion of the participants' arm in 10 degrees circulating water for two minutes.~The music sequences will be all 20 minutes, instrumental, professionally recorded in the studio and composed specifically for the Music Care application and are thus unfamiliar to participants. There will be two music conditions: the most-liked-music (MLM) and least-liked-music (LLM) conditions.
Study: NCT05162898

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: toripalimab
Description: 240mg,ivgtt, every three weeks as a cycle, the first day of each cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 12mg (weight ≥60kg) or 8mg (weight \<60kg) orally, once a day

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation
Description: ultrasound-guided percutaneous radiofrequency ablation of recurrent hepatocellular carcinoma
Study: NCT05327036

Intervention type: OTHER
Intervention: collect information about all participants
Description: collect information On age,pregnancy history,Height, weight,Gestational weeks of umbilical artery embolism,Gestational week of delivery, mode of delivery, newborn birth weight, birth height, Apgar score, umbilical cord length, umbilical cord placental insertion point, placental weight, pregnancy complications, coagulation function,after obtaining the consent of all participants.

Intervention type: OTHER
Intervention: collect information about all participants
Description: collect information On age,pregnancy history,Height, weight,Gestational weeks of umbilical artery embolism,Gestational week of delivery, mode of delivery, newborn birth weight, birth height, Apgar score, umbilical cord length, umbilical cord placental insertion point, placental weight, pregnancy complications, coagulation function,after obtaining the consent of all participants.

Intervention type: OTHER
Intervention: collect information about all participants
Description: collect information On age,pregnancy history,Height, weight,Gestational weeks of umbilical artery embolism,Gestational week of delivery, mode of delivery, newborn birth weight, birth height, Apgar score, umbilical cord length, umbilical cord placental insertion point, placental weight, pregnancy complications, coagulation function,after obtaining the consent of all participants.
Study: NCT05479461

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Hypertension Management System
Description: Mobile health technology using physician- directed, semi-automated management of hypertension

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: The participants will receive usual care
Study: NCT05243615

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guided internet delivered cognitive behavioural therapy
Description: A 10-week internet-delivered cognitive behavioural therapy (ICBT) will be delivered to participants who have sustained a stroke. In addition to the online program, a Guide with experience delivering ICBT will provide support by email or phone call once a week. The Guide will spend approximately 15 minutes per week/per client.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stroke rehabilitation mental health education
Description: A 10-week stroke-specific rehabilitation education program for stroke patients in usual care at specialized stroke rehabilitation units. The lessons will include information on spinal cord injury rehabilitation: 1)stroke basics, 2)mental health after stroke, 3)pain after stroke, 4)understanding rehabilitation 5)summary of lessons through an online platform. A Guide will check in with participants once a week to answer any content-related questions. The Guide will spend approximately 15 minutes per week/per client.