Study: NCT05378607

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Incentivization based on gradually increasing, externally chosen adherence goals
Description: Wisepill data on adherence will be collected remotely. Every three months, participants have a chance to participate in a prize drawing for an airtime reward of 500, 5,000, or 10,000 Ugandan Shillings if adherence matches or exceeds the subgoal chosen by the study coordinator. Subgoals will gradually increase from the participant's baseline adherence up to 90%. Prize drawings can be done during regularly scheduled clinic visits if the participant has a visit corresponding to the 3-month mark or remotely via SMS text message.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: End of year 1 adherence prize drawing
Description: Participants will have a chance to participate in a prize drawing at the end of year 1 with larger prize amounts of up to 20,000 Ugandan Shillings (approximately $6), where eligibility is based on reaching 90% in the three months preceding the end of year 1.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: End of year 1 adherence prize drawing
Description: Participants will have a chance to participate in a prize drawing at the end of year 1 with larger prize amounts of up to 20,000 Ugandan Shillings (approximately $6), where eligibility is based on reaching 90% in the three months preceding the end of year 1.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: End of year 1 adherence prize drawing
Description: Participants will have a chance to participate in a prize drawing at the end of year 1 with larger prize amounts of up to 20,000 Ugandan Shillings (approximately $6), where eligibility is based on reaching 90% in the three months preceding the end of year 1.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMS motivational messages + reminder of prize drawing
Description: Participants will receive weekly motivational messages with a reminder of their upcoming prize drawing throughout year 1 of the study.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMS motivational messages + reminder of prize drawing
Description: Participants will receive weekly motivational messages with a reminder of their upcoming prize drawing throughout year 1 of the study.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMS motivational messages + reminder of prize drawing
Description: Participants will receive weekly motivational messages with a reminder of their upcoming prize drawing throughout year 1 of the study.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Year 2 re-allocation based on year 1 performance
Description: In Year 2 of the study, participants who have reached 90% by the end of year 1 will no longer be given sub-goals and instead will be eligible for prize drawings if they maintain the fixed level of 90% or higher. Those who have not reached 90% by the end of year 1 will be allocated to the intervention group that showed the highest effectiveness in year 1.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Year 2 re-allocation based on year 1 performance
Description: In Year 2 of the study, participants who have reached 90% by the end of year 1 will no longer be given sub-goals and instead will be eligible for prize drawings if they maintain the fixed level of 90% or higher. Those who have not reached 90% by the end of year 1 will be allocated to the intervention group that showed the highest effectiveness in year 1.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Year 2 re-allocation based on year 1 performance
Description: In Year 2 of the study, participants who have reached 90% by the end of year 1 will no longer be given sub-goals and instead will be eligible for prize drawings if they maintain the fixed level of 90% or higher. Those who have not reached 90% by the end of year 1 will be allocated to the intervention group that showed the highest effectiveness in year 1.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: End of Year 2 viral suppression prize drawing
Description: Participants will have a chance to participate in a prize drawing at the end of Year 2 with larger prize amounts of up to 20,000 Ugandan Shillings (approximately $6), where eligibility is based on achieving viral suppression by the end of Year 2.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: End of Year 2 viral suppression prize drawing
Description: Participants will have a chance to participate in a prize drawing at the end of Year 2 with larger prize amounts of up to 20,000 Ugandan Shillings (approximately $6), where eligibility is based on achieving viral suppression by the end of Year 2.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: End of Year 2 viral suppression prize drawing
Description: Participants will have a chance to participate in a prize drawing at the end of Year 2 with larger prize amounts of up to 20,000 Ugandan Shillings (approximately $6), where eligibility is based on achieving viral suppression by the end of Year 2.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Incentivization based on gradually increasing self-chosen adherence goals
Description: Wisepill data on adherence will be collected remotely. Every three months, participants have a chance to participate in a prize drawing for an airtime reward of 500, 5,000, or 10,000 Ugandan Shillings if adherence matches or exceeds the self-chosen subgoal. While self-chosen, subgoals are subject to a minimum threshold determined by baseline adherence working towards 90% adherence. Prize drawings can be done during regularly scheduled clinic visits if the participant has a visit corresponding to the 3-month mark or remotely via SMS text message.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Incentivization based on a fixed adherence goal
Description: Wisepill data on adherence will be collected remotely. Every three months, participants have a chance to participate in a prize drawing for an airtime reward of 500, 5,000 or 10,000 Ugandan Shillings if adherence matches or exceeds the fixed adherence goal of 90%. Prize drawings can be done during regularly scheduled clinic visits if the participant has a visit corresponding to the 3-month mark or remotely via SMS text message.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: SMS motivational messages
Description: The control group will also receive weekly motivational messages but without the reminder of the upcoming prize drawing.