TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06046547

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary rehabilitation integrating education about palliative care
Description: PR will include exercise training twice a week, and education and psychosocial support once per week during 12 weeks.~The intervention will include an education session on palliative care, a Peer-to-peer session, a Get-apart session and online sessions.~The education session on palliative care will be facilitated by two specialist healthcare professionals. The main topics that will be discussed are: concept of palliative care, symptom control, disease impact, psychosocial support and planning for the future.~Participants will be the primary communicators in the Peer-to-peer session, and the dialogue will be based on their suggestions. Those who feel more reluctant to reveal private thoughts in front of their loved ones will have the opportunity to discuss their issues in a Get-apart environment.~Individual cases will be referred to a specialist palliative care team or to any other health/social care professional according to the unmet needs identified.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary rehabilitation
Description: Participants will receive the same PR program as the experimental group besides the education session on palliative care, the Peer-to-peer session, the Get-apart session and the online sessions (i.e. traditional pulmonary rehabilitation).
Study: NCT05750888

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: integrated exercise therapy with 3D printing exerciser for training intrinsic foot muscles
Description: The therapeutic exercise program with a custom-made 3-D printing foot core exerciser, consisting of warm-up exercise, active range of motion in the foot and ankle joints, foot core system strengthening program using the 3D printing device, and stretching exercises for foot and ankle.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: regular exercises for the elderly
Description: The regular exercise provided for the elderly in the dwelling community, including walking, simple aerobic exercises, stretching exercises
Study: NCT04589338

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Endurance training
Description: This group will perform aerobic type exercises. Initially, patients will perform continuous exercises of progressive intensity in order to adapt to this kind of effort. Next, we will introduce interval exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance training
Description: Patients in this group will perform lower limb strengthening exercises to improve the maximum strength of different muscle groups.
Study: NCT05911412

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based cognitive therapy using neuroscience (NMBCT)
Description: Mindfulness-based cognitive therapy using neuroscience (NMBCT) is a standardized 8-week course taught by trained instructors. The NMBCT is a group therapy that takes place once a week for about 90 minutes per session. The program consists of mental education for each session, 2-3 mindfulness meditation practice, mindfulness practice in daily life, and about 30 minutes of daily home mindfulness meditation task. While participating in the program, the subjects will receive psychoeducation and various mindfulness meditation techniques (eating meditation, breathing meditation, sedentary meditation, viewing meditation, and listening meditation, etc.).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based cognitive therapy using neuroscience (NMBCT)
Description: Mindfulness-based cognitive therapy using neuroscience (NMBCT) is a standardized 8-week course taught by trained instructors. The NMBCT is a group therapy that takes place once a week for about 90 minutes per session. The program consists of mental education for each session, 2-3 mindfulness meditation practice, mindfulness practice in daily life, and about 30 minutes of daily home mindfulness meditation task. While participating in the program, the subjects will receive psychoeducation and various mindfulness meditation techniques (eating meditation, breathing meditation, sedentary meditation, viewing meditation, and listening meditation, etc.).
Study: NCT05294341

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norethindrone Acetate 5 MG
Description: As specified in arm design

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norethindrone Acetate 5 MG
Description: As specified in arm design

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norethindrone 0.35 MG
Description: As specified in arm design

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norethindrone 0.35 MG
Description: As specified in arm design
Study: NCT04909216

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindful Attention Workshop
Description: The 90-minute workshop will include a 15-minute break and include up to 15 participants. The workshop will be led by peer support staff, fire department psychologists, and/or fire department doctoral psychology practicum students. Each workshop will be facilitate by up to 3 workshop leaders. The workshop will provide (1) psychoeducation regarding common mental health concerns among firefighters, (2) introduction to the concept of mindful attention, why it is relevant to firefighters, and how it can prevent or decrease mental health symptoms, (3) 5 experiential mindful attention training exercises, and (4) discussion. Workshop co-leaders will teach 5 mindful attention exercises, and firefighters will practice each exercise and then engage in discussion about their experiences and provide feedback regarding the utility of the exercise for them personally and for firefighters, generally.
Study: NCT05424835

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-A1811
Description: SHR-A1811

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib in combination with Capecitabine.
Description: Pyrotinib in combination with Capecitabine.
Study: NCT05849350

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whey protein
Description: Intake of whey protein
Study: NCT04511078

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Panitumumab-IRDye800
Description: single dose infusion of panitumumab-IRDye800CW
Study: NCT04833920

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: transcranial dirrect current brain stimuation
Description: tDCS (2 mA) targeting the primary motor cortex of the contralateral side of the painful side for 20 minute duration for five sessions in five consecutive days (one session /day),

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: transcranial dirrect current brain stimuation
Description: tDCS (2 mA) targeting the primary motor cortex of the contralateral side of the painful side for 20 minute duration for five sessions in five consecutive days (one session /day),
Study: NCT05904938

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lenodiar Pediatric
Description: Medical Device made of natural substance

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Product appearance similar to verum without clinical efficacy
Study: NCT05849350

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Intake of maltodextrin
Study: NCT05388604

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RF device
Description: The entire defined treatment area will then be treated by delivering adjacent pulses with minimal overlap of 10% or less. Parameters may be adjusted throughout the treatment in order to increase subject comfort.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microneedling device
Description: Test spots may be performed prior to the first treatment. Test spots may be performed prior to the first treatment. It will follow a similar procedure to treatment but only in an inconspicuous place, such as behind the ear, in an area no larger than 2in x 2in.~The tip will be placed in contact with the skin, and parameters may be adjusted throughout the treatment and will determined by the Clinician.
Study: NCT04797689

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trauma Informed Yoga
Description: One licensed yoga instructor, trained in trauma-informed yoga delivery, will lead the online sessions. Participants will be instructed to engage in the class from a mat or chair in their home or move between them as the class unfolds. The instructor will begin the class by introducing the week's theme (e.g. grounding and safety, non-attachment, imprints of the past and impacts on our reactions to COVID-19, connection to nature), followed by a breath practice (10 min), a yoga practice (50 min), a meditation practice (10 min), and closing words (10 min).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trauma Informed Psychotherapy
Description: Two licensed counsellors (MSW-trained) will co-facilitate the online version of this program. Facilitators will begin the session by introducing the week's theme (e.g. setting goals while working from home, being mindful, health coping) (10 min), followed by a lecture and activity to integrate learning (e.g. large and small group discussion using Zoom break out rooms, journaling) (70 min), and closing words (10 min).
Study: NCT05631171

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adhera® Fatigue Digital Program
Description: Adhera® Fatigue Digital Program, that includes an application and a smartwatch, is a digital health solution based on emotional and behavioral change techniques. Patient adaptative self-management content (e.g. psycho-educational content, activities for mental wellbeing, personalized motivational messages), and the personalization is based on Adhera® Health Recommender System.~Wearable devices and the mobile app will be used to collect real-time data for 3 months to detect biometric and psychometric (patient-reported outcomes) information.
Study: NCT06503822

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Long peripheral venous catheter
Description: In this study, patients eligible for admission were subjected to peripheral vein long catheter puncture according to the operating standards, daily routine maintenance until catheter removal, and relevant data were collected.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group (Short peripheral venous catheter)
Description: In this study, the patients eligible for admission will undergo peripheral venous short catheter puncture according to the operating standards, daily routine maintenance until catheter removal, and relevant data will be collected.
Study: NCT06556082

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training
Description: Proprioceptive Neuromuscular Facilitation(PNF) based upper extremity strengthening exercises to increase upper extremity muscle strength will be applied to the participants in the training group 3 days a week for 8 weeks. PNF-based upper extremity strengthening exercises will be performed with an elastic resistive band using bilateral symmetrical PNF patterns of Flexion-Adduction-External Rotation-Extension-Abduction-Internal Rotation, Flexion-Abduction-External Rotation-Extension-Adduction-Internal Rotation on two different diagonals while individuals are in a sitting position in a supported chair. Core Stabilization Training will be continued for 8 weeks by increasing the difficulty and intensity of the exercises with limb movements and floor modifications after the amputee football players are taught how to find their neutral spine and how to maintain the position.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Group
Description: The control group will be trained with isotonic strengthening exercises of upper extremity muscles with free weights and core stabilization training 3 days a week for 8 weeks. Isotonic exercises involve muscle contraction with movement, where the muscle length changes while maintaining constant tension. Free weights such as dumbells will be used in the implementation of the exercises. 1 Repetition Maximum (1RM) method will be used to determine the progression of the exercises.
Study: NCT05912595

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EXOPULSE Mollii Suit Stimulation
Description: We designed a randomized crossover, sham-controlled, double-blind trial to demonstrate the improvement of tissue oxygenation and frequent MS symptoms following a single session of active versus sham Exopulse Mollii suit. A 2-week washout period should be enough to prevent a potential carry over effect. After this phase (phase 1), a second open label phase (phase 2) will be proposed for patients to understand the effects of Exopulse Mollii suit employed for one month (3 sessions per week) on tissue oxygenation and MS related symptoms.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: EXOPULSE Mollii Suit Stimulation
Description: We designed a randomized crossover, sham-controlled, double-blind trial to demonstrate the improvement of tissue oxygenation and frequent MS symptoms following a single session of active versus sham Exopulse Mollii suit. A 2-week washout period should be enough to prevent a potential carry over effect. After this phase (phase 1), a second open label phase (phase 2) will be proposed for patients to understand the effects of Exopulse Mollii suit employed for one month (3 sessions per week) on tissue oxygenation and MS related symptoms.
Study: NCT06156878

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Anti-EGFR and PD-1 inhibitor arm
Description: Drug: PD-1 inhibitor and anti-EGFR monoclonal antibody The patients will receive radiotherapy (66-70.4Gy) combined with PD-1 inhibitor (every 3 weeks) and anti-EGFR monoclonal antibody (every 1 week). The specific treatment description is included in arm description.
Study: NCT05257421

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: shockwave machine
Description: shockwave therapy. 2000 impulses will be applied, 1000 on the TrPs and 1000 surrounding it, with Energy level up to 2,5 bars and frequency of 10Hz

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: leg and back exercises
Description: the exercise program will include 5 exercises that focuses on the back and lower limbs. These exercises are:~* Bridge~* Plank~* Squat~* Push-ups~* Back extension Each exercise will be done for 3-5 sets.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: shockwave and exercises
Description: both types of interventions will be applied for the patient
Study: NCT06215365

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adult cancer survivors who have completed their heavy treatments
Description: The study will be presented to the patient who can refuse to participate. The digital version of the questionnaire will be handed out, if the patient does not object after a period of thinking, when he or she comes to the day hospital for his or her JUMP Day. The study will therefore take place at a single point in time, and no pre-inclusion or follow-up visits are planned as part of this protocol.~Completing the questionnaire takes about 15 to 20 minutes. All questions are designed to meet the stated objectives. No personally identifiable data is collected.
Study: NCT05536882

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Benzoyl peroxide
Description: See arm description

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adapalene Gel
Description: See arm description
Study: NCT06196151

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Antenatal training
Description: Training hours: Training will be completed in a total of three weeks and six hours, two hours each week.~Method: The training will be given online via Zoom application. The training will consist of a total of three weeks and six hours, two hours each week. Informed Voluntary Consent Form will be obtained from individuals in both groups. Pregnant women in both the control and intervention groups will be asked to fill out the Women's Introductory Information Form. The data of the intervention group will be filled out before the first Antenatal education lesson and after all six-hour Antenatal education lessons are completed. The data of the control group will be filled in parallel with the intervention group.~Group to receive the training: Healthy pregnant women who are at the 20th gestational week at the earliest will be included in the training. Trainings will be carried out in closed groups.
Study: NCT05474287

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SJOV
Description: SJOV is conducted using a Wei nasal jet tube (WNJ, Well Lead Medical Co. Ltd, Guangzhou, China) which is connected to a manual jet ventilator (Well Lead Medical Co. Ltd, Guangzhou, China) via its jet port. The initial settings of SJOV were as follows: driving pressure (DP) 15 psi; respiratory rate (RR) 20 bpm; inspiratory-to-expiratory (I/E) ratio 1:2, and gas supply, 100% oxygen.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HFNO
Description: HFNO is conducted. Oxygen supplementation is delivered at 35 liters min-1 with a fraction of inspired oxygen (FiO2) of 100%.
Study: NCT05366127

Intervention type: OTHER
Intervention: IGA score
Description: IGA score will be assessed by 2 blinded investigators

Intervention type: OTHER
Intervention: BULLOUS PEMPHIGOID DISEASE AREA INDEX (BPDAI)
Description: BPDAI will be assessed by 2 by 2 blinded investigators
Study: NCT05739396

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stabilization
Description: The treatment session lasted one hour with short breaks of around 10 minutes and will be conducted three times per week for twelve successive weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stabilization
Description: The treatment session lasted one hour with short breaks of around 10 minutes and will be conducted three times per week for twelve successive weeks
Study: NCT05254236

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 Vaccine (Vero Cell), Inactivated (Medium-dose)
Description: Medium-dose COVID-19 Vaccine(Vero Cell),Inactivated: 600SU inactivated SARS-CoV-2 virus in 0.5 mL of aluminium hydroxide solution per injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVID-19 Vaccine (Vero Cell), Inactivated (High-dose)
Description: High-dose COVID-19 Vaccine(Vero Cell),Inactivated:1200SU inactivated SARS-CoV-2 virus in 0.5 mL of aluminium hydroxide solution per injection
Study: NCT04779450

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotherapy protocol
Description: The kinesiotherapy protocol is an exercise-based treatment designed to gain upper limb range of motion and muscle strengthening.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotherapy protocol
Description: The kinesiotherapy protocol is an exercise-based treatment designed to gain upper limb range of motion and muscle strengthening.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual orientations
Description: Usual orientations for post-breast cancer women, such as skin care, return to activities, upper limb functionality, self-care, lymphedema, and physical activity practice.
Study: NCT04545424

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hypothermia
Description: Subjects will be cooled using either cooling blankets or gel-pad systems to maintain core temperature 34-35°C.
Study: NCT05693389

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: acceptance and commitment therapy
Description: ACT attempts to encourage psychological flexibility, acceptance of one's own experiences, and dedication to behaviours that are consistent with one's own values. ACT therapies focus on six key processes to improve psychological flexibility: engagement with the present moment, acceptance, defusion, self as context, values clarification, and committed action.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: routine hospital care
Description: the patients with bipolar disorders who receive routine pharmacological treatment
Study: NCT04505189

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin assisted psychotherapy
Study: NCT04739904

Intervention type: OTHER
Intervention: Normoxia
Description: 48 hours experimental protocol conducted at sea level
Study: NCT04984460

Intervention type: DIAGNOSTIC_TEST
Intervention: Fluorescence morphological detection of liquid-based thin-layer film-making fungi
Description: Samples from outpatient or inpatient clinics to be tested for fungal vaginitis. A sample of one or more of the following characteristics. Symptoms: vulva pruritus, burning pain, but also accompanied by pain in urine and sexual pain and other symptoms; Leucorrhea increased.~Physical signs: Vulva flushing, edema, visible scratches or chaps, white membrane attached to the inner side of the labia minora and the vaginal mucosa, more white bean residue like secretions can be seen in the vagina, which can be curd.~Samples are human vaginal secretions. Each sample should be the amount on one swab.~The sample is not in menstrual period. The sample subjects did not have vaginal irrigation, medication or sexual intercourse within 3 days.
Study: NCT05850013

Intervention type: DEVICE
Intervention: Lifelight Junior
Description: Lifelight® is an app developed by xim that measures VS including heart rate, respiratory rate and blood pressure. All you need to do to have these vital signs measured is look at your smartphone or tablet camera for 20-40 seconds. The app has used data from over 1 million heartbeats to learn how to measure these vital signs in adults. The technology is already available for doctors and nurses to use with adult patients in some specific scenarios
Study: NCT04545424

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neuromuscular Blocking Agents
Description: Subjects in the TH + NMB arm will be deeply sedated using agents at the discretion of the primary ICU team, then start continuous iv infusion of either cisatracurium, atracurium, or vecuronium titrated to 2 twitches on train of four monitoring and further titrated to ablate visible shivering.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Subjects who are hypothermic (≤36°C) during CRRT will receive surface warming to restore core temperature to 37°C. Patients with core temperature \>38°C will receive 650 mg acetaminophen and, if temperature remains \>38°C, surface cooling will be initiated to return core temperature to 37-38°C.