TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06051747

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Three-dimensional patient-specific bioprinting trachea implantation
Description: The intervention entails the creation of a 3D cell-printed tracheal organ, achieved through the fusion of biopolymer materials and the bioprinting (3D cell printing) technique. This process involves distribution of nasal cavity stem cells (hNTSCs) and nasal septum cartilage cells (hNCs) within hydrogel matrices, culminating in the formation of a personalized tracheal structure.
Study: NCT06126133

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near Infrared Spectroscopy
Description: Two NIRS probes will be attached to the extremity to be operated on and to the other lower extremity on the opposite side, at a level approximately coinciding with the midline above the quandriceps femoris muscle.
Study: NCT06256107

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Headset
Description: Virtual Reality Headset
Study: NCT04532866

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Isolation and Confinement
Description: Eight months of isolation and confinement in the spaceflight analog NEK in Moscow
Study: NCT05526612

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group 1 Motor imagery and Bobath Therapeutic Approach (BTA+MI)
Description: Motor imagery (MI) is the mental rehearsal of motor abilities to improve function. Without revealing any movement in the body, the representation of the movement is created in the mind, the person imagines that he/she is performing the movement. Eating activity will be applied in motor imagery. Individualized therapy sessions in the Bobath Therapeutic Approach will also be received by the Physiotherapist along with Motor imagery. 2 days a week, 30 minutes session will be applied for a total of 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group 2 Motor imagery, Bobath Therapeutic Approach and Physical practice (BTA+MI+PP)
Description: Individualized therapy sessions in the Bobath Therapeutic Approach with motor imagery will be performed by the physiotherapist, and in addition to these, 5 repetitions of the eating activity used in motor imagery will be practiced. 2 days a week, 30 minutes session will be applied for a total of 8 weeks.
Study: NCT05383989

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: UniVenture Sensation Seeking manual
Description: Intended for those who score at least 0.5 standard deviation (SD) above the population-specific norm on Sensation Seeking (SS) personality traits on the Substance Use Risk Profile Scale (SURPS)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: UniVenture Impulsivity manual
Description: Intended for those who score at least 0.5 standard deviation (SD) above the population-specific norm on Impulsivity (IMP) personality traits on the Substance Use Risk Profile Scale (SURPS).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: UniVenture Impulsivity manual
Description: Intended for those who score at least 0.5 standard deviation (SD) above the population-specific norm on Impulsivity (IMP) personality traits on the Substance Use Risk Profile Scale (SURPS).

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Service as usual provided by the University
Description: It is the regular university-provided well-being services.
Study: NCT05507190

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-management of post COVID-19 respiratory outcomes
Description: Intervention: using the participants' initial assessment, personal characteristics, main complaints/needs and goals, the therapist will adjust the exercise plan and personalize the recommendations (e.g. maximum heart rate) as well as instruct the patients about safety precautions (how to pace themselves, when to seek professional or emergency care). Participants will be encouraged to wear the smart shirt as much as they want during the 6 weeks (29), but at a minimum of 1-hour a day (M-F) including while performing the recommended exercises (30-45 min/3 times a week). They should self-monitor their biometric values trying to reach/stay within the target values while wearing the shirt using Hexoskin app installed on an iPad provided by the research team or on the participants' personal device if preferred.
Study: NCT05592782

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Based Mindfulness meditation
Description: Participants will undergo a guided VR meditation using a commercial VR application. The meditation will last approximately 15 minutes. Prior to starting and on upon completion of each VR meditation session, participants' state pain, anxiety, depression, and stress will be assessed. For each participant enrolled, baseline and monthly assessments using the DASS-21 and PPI-SFI3a will be performed for three consecutive months.
Study: NCT05332509

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: C-BRACE
Description: The C-BRACE is a custom made Knee-Ankle-Foot-Orthosis with a microprocessor-controlled hydraulic knee-joint articulation. The C-BRACE technology offers to a patient with knee locking deficiencies the following advantages: approximation of the physiological gait pattern, stability while standing and walking, adaptation to various surfaces, inclines, gait situations and walking speeds.

Intervention type: DEVICE
Group type: OTHER
Intervention: C-BRACE
Description: The C-BRACE is a custom made Knee-Ankle-Foot-Orthosis with a microprocessor-controlled hydraulic knee-joint articulation. The C-BRACE technology offers to a patient with knee locking deficiencies the following advantages: approximation of the physiological gait pattern, stability while standing and walking, adaptation to various surfaces, inclines, gait situations and walking speeds.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SCO
Description: The SCO is a custom made Knee-Ankle-Foot-Orthosis with a knee-joint locked during stance phase and released during swing phase.

Intervention type: DEVICE
Group type: OTHER
Intervention: SCO
Description: The SCO is a custom made Knee-Ankle-Foot-Orthosis with a knee-joint locked during stance phase and released during swing phase.
Study: NCT05861856

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual therapy
Description: Mobilization for the spine, mobilization and relaxation methods for the soft tissues around the spine will be performed.
Study: NCT05096832

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)
Description: Appearance: Creamy white suspension Dosage form: Suspension for injection Strength: 10 μg (0.5 mL) /vial Vaccination route: Intramuscular injection into the lateral deltoid of the upper arm Vaccination dosage: 10 μg (0.5 mL) Immunization schedule: 1 dose on Day 0, which should be 3-6 months after the second dose of 2-dose regimen of inactive vaccine (BBIBP-CorV or CoronaVac).~Storage condition: Store at 2-8 °C protected from light Expiry date: 24 months temporarily

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Blank Preparation of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)
Description: The dosage, appearance, administration method, and other aspects are consistent with that of investigational vaccine, except that no vaccine antigen is contained.
Study: NCT05861856

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual therapy
Description: Mobilization for the spine, mobilization and relaxation methods for the soft tissues around the spine will be performed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality
Description: Virtual reality supported core stabilization exercises will be performed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality
Description: Virtual reality supported core stabilization exercises will be performed.
Study: NCT05125978

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Canadá
Description: Canadá association 1 tablet twice a day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Canadá placebo
Description: Placebo of Canadá association 1 tablet twice a day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Canadá placebo
Description: Placebo of Canadá association 1 tablet twice a day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dipyrone
Description: Dipyrone 1 tablet twice a day

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dipyrone placebo
Description: Placebo of dipyrone 1 tablet twice a day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dipyrone placebo
Description: Placebo of dipyrone 1 tablet twice a day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol hydrochloride
Description: Tramadol 1 coated tablet twice a day

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tramadol hydrochloride placebo
Description: Placebo of tramadol 1 coated tablet twice a day

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol hydrochloride placebo
Description: Placebo of tramadol 1 coated tablet twice a day
Study: NCT05132140

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: adaptive optics system
Description: the system consists of a wavefront sensor and a deformable mirror that measure and correct (or modify) the eye's optical imperfections (aberrations).
Study: NCT05468931

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prostate stimulator
Description: Prostate stimulation device for sexual dysfunction
Study: NCT05696613

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNP-ACTH (1-39) Gel
Description: Subjects will be randomly assigned in 1:1 treatment allocation ratio to receive the test and reference product.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNP-ACTH (1-39) Gel
Description: Subjects will be randomly assigned in 1:1 treatment allocation ratio to receive the test and reference product.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNP-ACTH (1-39) Gel
Description: Subjects will be randomly assigned in 1:1 treatment allocation ratio to receive the test and reference product.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: Subjects will be randomly assigned in 1:1 treatment allocation ratio to receive the test and reference product.
Study: NCT04399486

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical Therapy
Description: Physical Therapy is a therapeutic exercise, education and functional activities provided on a one to one basis with a licensed Physical Therapist to meet functional goals.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Therapy
Description: Physical Therapy is a therapeutic exercise, education and functional activities provided on a one to one basis with a licensed Physical Therapist to meet functional goals.
Study: NCT06527131

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: pulsed electromagnetic field therapy
Description: PEMF is regarded as an efficient physical therapy method that has been utilized clinically to treat a variety of orthopedic conditions, including delayed union and nonunion of fractures. According to studies, PEMF has been authorized for its biological effects, which include the mineralization of bone matrix, osteogenic differentiation of mesenchymal stem cells, and osteoblast proliferation

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutanous electrical nerve stimulation
Description: Electrical stimulation consider a safe and cost-effective method for pain management. It has no side effects and few contraindication in addition to no drug interaction . According to studies ,electrical stimulation decreases pain through reducing central transmission of pain signals because of nociceptive inhibition at the presynaptic level in the dorsal horn.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutanous electrical nerve stimulation
Description: Electrical stimulation consider a safe and cost-effective method for pain management. It has no side effects and few contraindication in addition to no drug interaction . According to studies ,electrical stimulation decreases pain through reducing central transmission of pain signals because of nociceptive inhibition at the presynaptic level in the dorsal horn.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin
Description: medical antibiotics
Study: NCT06407544

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: peripheral nerve block
Description: peripheral nerve block guided by ultra sound through Ultrasound-guided quadratus lumborum block versus FICB or fascia iliaca block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: peripheral nerve block
Description: peripheral nerve block guided by ultra sound through Ultrasound-guided quadratus lumborum block versus FICB or fascia iliaca block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: peripheral nerve block
Description: peripheral nerve block guided by ultra sound through Ultrasound-guided quadratus lumborum block versus FICB or fascia iliaca block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PCA device as rescue medication with IV morphine 1mg if VAS more than 4
Description: PCA device as rescue medication with IV morphine 1mg if VAS more than 4 with a 10 min lock-out time

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PCA device as rescue medication with IV morphine 1mg if VAS more than 4
Description: PCA device as rescue medication with IV morphine 1mg if VAS more than 4 with a 10 min lock-out time
Study: NCT05096429

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PROVIDENT
Description: Each of the state's 39 municipalities will be randomised to the intervention (PROVIDENT) or comparator condition. An interactive, web-based tool will be developed to visualize the PROVIDENT model predictions. Municipalities assigned to the treatment arm will receive neighborhood risk predictions from the PROVIDENT model, and state agencies and community-based organizations will direct resources to neighborhoods identified as high risk. Municipalities assigned to the control arm will continue to receive surveillance information and overdose prevention resources, but they will not receive neighborhood risk predictions from this study.
Study: NCT06407544

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PCA device as rescue medication with IV morphine 1mg if VAS more than 4
Description: PCA device as rescue medication with IV morphine 1mg if VAS more than 4 with a 10 min lock-out time
Study: NCT06146426

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Early diet resumption
Description: Resuming oral diet at pace started from 2 hours after extubation from ventilator.
Study: NCT05569200

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Haifu Focused Ultrasound tumor therapeutic System
Description: The device used in this trial will be Haifu Focused Ultrasound tumor therapeutic System. In Uterine benign tumor female, the investigators will observe the possibility of complication and tumor response of treatment.
Study: NCT05518370

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hippotherapy simulator training
Description: Hippotherapy simulator training will be designed for the individual basis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physiotherapy
Description: Traditional physiotherapy within a specific program

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physiotherapy
Description: Traditional physiotherapy within a specific program
Study: NCT05845944

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video-supported education group
Description: Providing training on nutrition with a nasogastric tube in pediatric patients with a video-supported education method
Study: NCT04851821

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Quercetin
Description: Each patient included, after signing the consent, will have a treatment for ten days: one tablet times three per day 30 minutes before the meal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quercetin
Description: Each patient included, after signing the consent, will have a treatment for ten days: one tablet times three per day 30 minutes before the meal.
Study: NCT05938920

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INS018_055
Description: Pharmaceutical formulation: Capsules~Mode of Administration: Oral

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical formulation: Capsules~Mode of Administration: Oral
Study: NCT04453033

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Celeste Specialized Phototherapy Device
Description: Ocular phototherapy light panel

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Celeste Specialized Phototherapy Device
Description: Ocular phototherapy light panel
Study: NCT06509503

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Combined oral contraceptive
Description: The arm will include 200 migraine patients diagnosed according to ICHD3-beta criteria. The patients are regular users of COCs and will receive propranolol 80-160mg daily and ibuprofen 200-400 mg only in acute migraine attacks for 3 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal Ring
Description: The arm will include 200 migraine patients diagnosed according to ICHD3-beta criteria. The patients are users of mechanical contraceptive methods and will receive propranolol 80-160mg daily and ibuprofen 200-400 mg only in acute migraine attacks for 3 months.
Study: NCT05077709

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IO102-IO103 in combination with pembrolizumab
Description: The experimental drug IO102-IO103 is for SC injection and consist of IDO and PD-L1 peptides

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IO102-IO103 in combination with pembrolizumab
Description: The experimental drug IO102-IO103 is for SC injection and consist of IDO and PD-L1 peptides

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IO102-IO103 in combination with pembrolizumab
Description: The experimental drug IO102-IO103 is for SC injection and consist of IDO and PD-L1 peptides
Study: NCT03970954

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: low-dose IL-2
Description: Subcutaneous injection of low dose of IL-2 for induction course of 5 days, the 10th day after the beginning of periods. At most 5 courses of low dose of IL-2.
Study: NCT04576832

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Attention Training (MBAT) web-course
Description: Pre-recorded weekly sessions for 4 weeks. Each session will consist of approximately 2 hours of video content per week and weekly mindfulness exercises. This video will include MBAT program lectures, pre-recorded testimony from military leaders, and teaching materials. The course will also include 15-min daily mindfulness practice drills.
Study: NCT05232266

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caralluma Fimbriata
Description: Caralluma fimbriata in capsule form - taken as a 500mg dose (two 250mg capsules) twice daily, morning and evening with food.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo comparator - Microcrystalline cellulose
Description: Placebo comparator in capsule form - taken as a 500mg dose (two 250mg capsules) twice daily, morning and evening with food.
Study: NCT04576832

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness-Based Attention Training (MBAT) web-course
Description: Pre-recorded weekly sessions for 4 weeks. Each session will consist of approximately 2 hours of video content per week and weekly mindfulness exercises. This video will include MBAT program lectures, pre-recorded testimony from military leaders, and teaching materials. The course will also include 15-min daily mindfulness practice drills.
Study: NCT06510751

Intervention type: OTHER
Intervention: CGRP level
Description: CGRP and substance P levels will be analysed by ELISA method in CSF and blood materials.
Study: NCT05072574

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Specific dietary treatment and follow-up using coaching techniques
Description: Intervention group will receive specific dietary treatment and follow-up using coaching techniques, supported by new technologies, and will attend a nutritional education program
Study: NCT04804735

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: REV : local anesthesia and virtual reality
Description: REV : local anesthesia and virtual reality in Implanted Venous Access Device (IVAD) procedure under local anesthesia

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MUS : local anesthesia and music therapy
Description: MUS : local anesthesia and music therapy in Implanted Venous Access Device (IVAD) procedure under local anesthesia
Study: NCT04479683

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FTH then DH support
Description: FTH output and DH relay one day a week until the minimum healthy weight. This treatment combines over one day a medical evaluation by a senior psychiatrist, family work (parents group and multi-family therapy session), a therapeutic education group, a cognitive remediation group and a dietary follow-up with therapeutic meals.~During this phase, all children are evaluated once a week on a somatic level.

Intervention type: OTHER
Group type: OTHER
Intervention: standard care
Description: continuation of full-time hospitalization until the minimum healthy weight is reached, defined as the weight corresponding to the return to the previous BMI corridor (previous BMI +/- 1 BMI corridor, e.g. change from 25th to 10th percentile). This management combines bi-weekly medical follow-up by a senior psychiatrist, weekly family work, weekly therapeutic education group, weekly cognitive remediation group and bi-weekly dietary follow-up with therapeutic meals.
Study: NCT05015790

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality Bliss Solution
Description: use virtual reality Bliss Solution
Study: NCT05794074

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: luteine and zeaxanthine
Description: luteine and zeaxanthine
Study: NCT05339594

Intervention type: DEVICE
Intervention: NeuraGen
Description: NeuraGen nerve guide is an absorbable implant for the repair of peripheral nerve gaps.

Intervention type: DEVICE
Intervention: NeuraGen 3D
Description: NeuraGen 3D Nerve guide matrix is a resorbable implant for the repair of peripheral nerve gaps.
Study: NCT05593614

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATX01 10%
Description: A 100 mL bottle of hydrogel formulation containing 10% amitriptyline hydrochloride w/w

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATX01 15%
Description: A 100 mL bottle of hydrogel formulation containing 15% amitriptyline hydrochloride w/w