TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05361304

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: senofilcon A contact lenses made with a novel manufacturing technology
Description: TEST Lens
Study: NCT05397119

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: H5N1 IIV - IM
Description: 90 µg H5N1 IIV administered intramuscularly (1 mL) One booster dose administered 6 months following last immunization
Study: NCT06213389

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EzVision® videolaryngoscopy
Description: Patient will be intubated with EzVision® videolaryngoscopy

Intervention type: DEVICE
Group type: OTHER
Intervention: Macintosh Blade
Description: Patient will be intubated with Macintosh Blade
Study: NCT05121779

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI
Description: Intravenous injection of one dosage of 18.5-22.2MBq (0.5-0.6 mCi)/Kg 68Ga-FAPI. Tracer doses of 68Ga-FAPI will be used to image lesions of pulmonary fibrosis by PET/CT.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-FDG
Description: Intravenous injection of one dosage of 4.44-5.55 MBq(0.12-0.15mCi)/Kg 18F-FDG. Tracer doses of 18F-FDG will be used to image lesions of pulmonary fibrosis by PET/CT.
Study: NCT05361304

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: senofilcon A contact lenses made with the current manufacturing technology
Description: CONTROL Lens
Study: NCT06288750

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Indocyanine Green
Description: ICG is a fluorescent dye which binds tightly to plasma proteins and becomes confined to the vascular system.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: No indocyanine green
Description: Conventional means of identification and assessment of PGs are mainly based on surgeon-dependent identification of their anatomical location and appearance (color, shape, etc.) by the naked eye.
Study: NCT05658484

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dimethyl fumarate
Description: Administered as specified in the treatment arm.
Study: NCT05622773

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mat use application
Description: In the research, repeated measurements will be made by using mats and foot baths in a single group and the data will be recorded.
Study: NCT05417711

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Vagus Nerve Stimulation Paired with Tailor-Made Notched Music Therapy
Description: The pulse frequency of vagus nerve stimulation is 25 Hz, the pulse width is 200 US, and the intensity is 1-10 mA. Tailor-made notched music is produced by filtering a frequency band of 1/2 octave width centered at the individual tinnitus frequency. When two sides of tinnitus frequencies are different, each side of music are filtered respectively, according to the different tinnitus frequency. When only have unilateral tinnitus or bilateral tinnitus in the same central frequency, both sides of music are filtered with the same tinnitus frequency. The tVNS and TMNM begin at the same time during treatment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Tailor-made Notched Music Training
Description: Tailor-made notched music is produced by filtering a frequency band of 1/2 octave width centered at the individual tinnitus frequency. When two sides of tinnitus frequencies are different, each side of music are filtered respectively, according to the different tinnitus frequency. When only have unilateral tinnitus or bilateral tinnitus in the same central frequency, both sides of music are filtered with the same tinnitus frequency. At the beginning of TMNMT, 10 seconds sham vagus nerve stimulation is output, whose parameters are as same as experimental group.
Study: NCT04559373

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality and Field Training (VRFT)
Description: The VRFT intervention involves the intensive practice of community ambulation skills. Some of the training sessions will be performed in a virtual environment, while others will consist of field training exercises in the community. During the intervention, stroke participants will be invited to practice different dimensions of community ambulation, such as postural transitions, avoiding other pedestrians, dual-task walking, etc.
Study: NCT06502457

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: painkiller
Description: The control group will receive a painkiller adapted to the service protocol after the fetal heart rate has been recorded.
Study: NCT06473558

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Biometrics (or AI Biomaker)
Description: Patients will be asked to read a story and their facial expressions and audio cues will be recorded.
Study: NCT06502457

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hypnosis group
Description: The hypnosis group will receive a hypnosis session after the fetal heart rate has been recorded. Automated measurement of blood pressure and maternal heart rate will take place during the session in order to objectively assess the impact of the session on the mother.~Patients in the hypnosis group will then have access to the virtual reality headset on request throughout the latency or maturation phase, and will also be able to benefit from a painkiller in accordance with the service protocol if they so request.
Study: NCT05153018

Intervention type: OTHER
Group type: OTHER
Intervention: Blood collection
Description: a 4-mL blood sample collected in a dry tube
Study: NCT06316804

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video Intervention 1
Description: A self-administered video-based mobile app with narratives on mental illness. The content of the videos consists of individuals sharing their personal experiences with depression and anxiety.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Video Intervention 2
Description: A self-administered video-based mobile app with narratives on mental illness. The content of the videos consists of individuals sharing their personal experiences with depression and anxiety.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Video Intervention 3
Description: An experimental self-administered video-based mobile app with narratives on mental illness after the waitlist period has been completed. The content of the videos consists of individuals sharing their personal experiences with depression and anxiety.
Study: NCT06073041

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Invitation to adopt
Description: All eligible Prisma Health clinics will be invited to adopt EIMG. Adopting clinics will first be sent an instructional video as a part of a low touch initial onboarding. After 4 months, clinics will then receive an in-depth standardized onboard training.
Study: NCT06524401

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Limpet
Description: Limpet participants will have their device placed by a clinician. Upon discharge, a portable vacuum pump will be issued to provide negative pressure (e.g., 3M Prevena or Snap; ConvaTec Avelle; or Pensar MicroDoc). These systems are compact, fit in a pocket, are simple to operate, and commonly used in the outpatient setting to provide multiple weeks of therapy. Participants will be furnished with materials to address potential dressing problems while at home: extra waste pouches, adhesive drape strips for sealing air leaks, and standard of care adhesive ostomy pouches and accessories as a backup plan in the event of a Limpet failure.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Control participants will receive standard of care adhesive ostomy pouch dressings. Participants will be furnished with materials to address potential dressing problems while at home: adhesive ostomy pouches and accessories for pouch replacement. The Control group will change their pouches at home 2 to 5 times per week or more frequently if needed, as per the current standard of care.
Study: NCT06558630

Intervention type: PROCEDURE
Intervention: Endotracheal intubation
Description: Over the course of several years as many as possible ED centres in the Netherlands will be included in the collection of all data involving airway management. Airway management is defined as the process of planning, preparation and execution of endotracheal intubation.
Study: NCT05401123

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: milking pump
Description: n the study, all mothers who come to the Lactation/Relactation outpatient clinic will be informed about the study, and mothers who accept the study will have to fill out the Conformity to Criteria Form created by the researcher. Between the ages of 20-35, postpartum 1-5. Participants who gave birth after the 37th week of pregnancy, did not have literacy problems, mental disabilities and communication problems, did not have chronic diseases, did not use any medication, and volunteered to participate in the study will be included in the study. by milking, 2 ml of first milk will be taken from the participants in the control group (via the milking pump). The collected milk will be taken to the laboratory for analysis by the researcher.
Study: NCT04341363

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tattoo machine
Description: A SOL Nova Device (brand) tattoo machine will be used to stimulate hair regrowth.
Study: NCT06534138

Intervention type: BEHAVIORAL
Intervention: Physical exercise
Description: The CP-exercise group was categorized based on patients' self-reported daily exercise time into four levels: 15 minutes/day, 30 minutes/day, 45 minutes/day, and ≥60 minutes/day. Additionally, resistance exercise and endurance exercise were distinguished based on patients' self-reported exercise modalities, including swimming, jogging, brisk walking, practicing Tai Chi, and dumbbell training.
Study: NCT05282004

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOK583A1
Description: SOK583A1 will be provided in a vial kit, with 40 mg/mL of aflibercept solution for IVT injection (2 mg/0.05 mL)
Study: NCT05996549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quadrivalent Influenza Vaccine
Description: All high-risk groups have been getting one dose of seasonal influenza vaccination (Inactivated Influenza Vaccine ), except children aged six months to 8 years, who will receive two doses four weeks apart. All vaccines are in the southern hemisphere, as Bangladesh's influenza season matches the southern hemisphere areas.
Study: NCT05546606

Intervention type: DEVICE
Group type: OTHER
Intervention: ECCO2R
Description: ECCO2R therapy using the Xenios platform, CE-marked medical device of the firm Xenios AG (Heilbronn, Germany), including the following components: Xenios console, iLA active iLA Kit IPS and Novaport Twin (18Fr, 22Fr or 24 Fr) cannulas The maximal duration of ECCO2R therapy with one circuit will be of 29 days in agreement with the regulatory approval of the patient kit.
Study: NCT04741425

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: REST intervention
Description: The breastfeeding talk will be conducted by Zoom at the third trimester about breastfeeding benefits and other practical advices. There is also a sharing session by a successful breastfeeding mother and a group discussion with different breastfeeding scenarios.~Once the mothers return home after delivery, individualized breastfeeding coaching will be provided by PI through a daily Zoom videoconference within 24 hours upon hospital discharge till Day 7 after delivery.~During the last breastfeeding videoconference, mothers will be reminded to have weekly telephone follow-ups by PI from week 2 to 2 months postpartum.~Women who are randomised into the intervention group will receive REST in addition to the standard antenatal and postnatal care (described at below) by the Obstetrics Department of their delivery hospitals.
Study: NCT05296616

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Stress Reduction Intervention
Description: Mindfulness Based Stress Reduction intervention is a manualized course that includes meditation, relaxing movement, and breathing. A certified MBSR instructor will teach the courses in a group-based format for 90 minute sessions, once per week for eight weeks.
Study: NCT05331742

Intervention type: DRUG
Intervention: Vaccine
Description: patients who have received vaccine against coronavirus disease infection
Study: NCT06531525

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enoxaparin
Description: Enoxaparin 4000 IU/day by subcutaneous injection at the time of randomization and continued until delivery. Dose adjustments were made throughout the study based on symptoms such as bleeding and thrombosis.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin
Description: Aspirin 75mg, orally, once daily at the time of randomization and continued until delivery. Dose adjustments were made throughout the study based on symptoms such as bleeding and thrombosis.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin
Description: Aspirin 75mg, orally, once daily at the time of randomization and continued until delivery. Dose adjustments were made throughout the study based on symptoms such as bleeding and thrombosis.

Intervention type: DRUG
Group type: OTHER
Intervention: Enoxaparin
Description: Participants in all groups will receive daily injections of enoxaparin at a dose of 4000 IU within 6 weeks at postpartum.
Study: NCT06267482

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ROSA PSA Parapatellar Approach
Description: This intervention will consist of using the ROSA alongside patient-specific alignment. The knee incision will be the same as the standard of care (medial parapatellar approach).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ROSA PSA Subvastus Approach
Description: This intervention will consist of using the ROSA alongside patient-specific alignment. The knee incision will be an alternative, quad-sparring, subvastus approach.
Study: NCT06460623

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: external mobilization
Description: two 5-minute sessions of external manipulation per week over a 5-week period.
Study: NCT06566924

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Students in the control group were taken to the laboratory practice within one week after the training presentation. Students were expected to act in accordance with the skills of isolation precautions in line with the 'Sample Scenario'.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training Group for Standardised Patient Simulation
Description: One week after the training presentation, the experimental group was invited to the simulation training. Simulation training was carried out in a hospital environment. Materials to be used in standardised patient and isolated patient care were made availa
Study: NCT06341192

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single-bundle ACL combined anterolateral ligament reconstruction
Description: Single-Bundle ACL + ALL Reconstruction Group:~Patients in this group will undergo reconstruction of the anterior cruciate ligament (ACL) using a single-bundle graft technique.~In addition, they will have the anterolateral ligament (ALL) reconstructed using a portion of the same graft material.~The single ACL bundle is typically positioned to replicate the anatomic footprint of the native ACL.~For the ALL reconstruction, a commonly used technique is the Sonnery-Cottet ALL reconstruction using a gracilis tendon graft.~This combines an intra-articular ACL reconstruction with an extra-articular lateral tenodesis to improve rotational instability.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Double-bundle ACL combined anterolateral ligament reconstruction
Description: Double-Bundle ACL + ALL Reconstruction Group:~Patients in this group will undergo anatomic double-bundle ACL reconstruction using two graft bundles to more anatomically replicate the native ACL\&#39;s anteromedial and posterolateral bundles.~Like the single-bundle group, they will also have supplemental ALL reconstruction performed using a portion of the graft material.~The double-bundle ACL reconstruction aims to better restore the ACL\&#39;s complex anatomic footprint and bundles\&#39; tension patterns.
Study: NCT06460623

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: rectal coccygeal mobilization
Description: consisted of two 5-minute sessions of external manipulation per week over a 5-week period.
Study: NCT06300645

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SPLATT
Description: split tibialis anterior tendon transfer to peroneus brevis total tibialis anterior tendon transfer to lateral cuneiform

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SPLATT
Description: split tibialis anterior tendon transfer to peroneus brevis total tibialis anterior tendon transfer to lateral cuneiform
Study: NCT06059469

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ga-PSMA PET/CT
Description: Patient undergo Ga-PSMA PET/CT prior to the start of the new drug treatment
Study: NCT06562439

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sickle Cell Collaboration for Child Development
Description: The Sickle Cell Collaboration for Child Development (SCCCD) combines the Parents as Teachers curriculum with experienced occupational therapy to help families and children meet their learning and developmental goals.
Study: NCT05109910

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic lymph node dissection
Description: Bilateral extended pelvic lymph node dissection
Study: NCT05495503

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prototype (814A-v1)
Description: Application on PIH located on the dorsal area (2 treatments during the study).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prototype (814B-v1)
Description: Application on PIH located on the dorsal area (2 treatments during the study).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prototype (814C-v1)
Description: Application on PIH located on the dorsal area (2 treatments during the study).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prototype (814D-v1)
Description: Application on PIH located on the dorsal area (2 treatments during the study).
Study: NCT05162326

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BC-101
Description: Human umbilical cord tissue derived mesenchymal stem cells (hUC-MSC) suspension at concentration of 2, 4, or 6 million cells/mL.
Study: NCT06366204

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary Lysine Intakes
Description: Participants consume 8 hourly meals that contain the assigned test lysine intake. Each meal will provide one-twelfth of the participants' daily energy requirements as estimated by 1.7 x Resting Energy Expenditure (REE) and adequate protein at 1.5 g.kg.d, to maintain a metabolic steady state. The meals are in the form of a crystalline amino acid protein shake, and nitrogenous free cookies.
Study: NCT06173817

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: isocapnic hyperventilation
Description: isocapnic hyperventilation (iHV) increases the elimination of methanol to the extent that it could replace haemodialysis for elimination purposes when haemodialysis is not required for the correction of acidosis, and alcohol dehydrogenase (ADH) is completely blocked by an antidote.
Study: NCT04790045

Intervention type: DRUG
Group type: OTHER
Intervention: Venetoclax
Description: Core-needle biopsy to be performed before starting treatment in patients candidates to venetoclax-based regimens
Study: NCT06410859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botulinum Toxin Type A for Injection,also known as HengLi®
Description: This study plans to enroll 240 subjects, and the efficacy measures \[VAS score, DSIS score, daily pain duration (if applicable), and number of daily pain episodes\] will be collected from subjects using the electronic Patient-Reported Outcomes (ePRO) throughout the study. The study period mainly consists of a screening period (14 days before the first dose), a double-blind treatment period (from the first dose to Week 12), and an extension period (from Week 13 to Week 52), including a maximum of 4 treatment cycles (each cycle lasts 12 week)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botulinum Toxin Type A for Injection,also known as HengLi®
Description: This study plans to enroll 240 subjects, and the efficacy measures \[VAS score, DSIS score, daily pain duration (if applicable), and number of daily pain episodes\] will be collected from subjects using the electronic Patient-Reported Outcomes (ePRO) throughout the study. The study period mainly consists of a screening period (14 days before the first dose), a double-blind treatment period (from the first dose to Week 12), and an extension period (from Week 13 to Week 52), including a maximum of 4 treatment cycles (each cycle lasts 12 week)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botulinum Toxin Type A for Injection,also known as HengLi®
Description: This study plans to enroll 240 subjects, and the efficacy measures \[VAS score, DSIS score, daily pain duration (if applicable), and number of daily pain episodes\] will be collected from subjects using the electronic Patient-Reported Outcomes (ePRO) throughout the study. The study period mainly consists of a screening period (14 days before the first dose), a double-blind treatment period (from the first dose to Week 12), and an extension period (from Week 13 to Week 52), including a maximum of 4 treatment cycles (each cycle lasts 12 week)
Study: NCT05650658

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: His/LBBP
Description: Pacing at the level His-Bundle or left bundle branch is used to correct the underlying conduction abnormality, resulting in a faster and more homogeneous activation of the heart pacing directly via the intrinsic conduction system of the heart accompanied by a right atrial endocardial lead and a right ventricular defibrillator endocardial lead for LVEF≤35% and by a right atrial endocardial lead for LVEF 36-50%.
Study: NCT04879238

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BEING
Description: 60 minute yoga session that blends mindfulness techniques
Study: NCT05650658

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BiVP
Description: Biventricular pacing has been shown to improve outcomes by delivering synchronized electrical stimuli to the right and left ventricles utilizing an an endocardial right atrial lead, an endocardial right ventricular lead, and an epicardial left ventricular lead implanted in a branch of the coronary sinus.~For LVEF≤35% a biventricular pacemaker-defibrillator will be implanted while for LVEF 36-50% a biventricular pacemaker will be implanted.
Study: NCT06113783

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HYALUBRIX 60
Description: 1.5% solution of non-modified HA (60mg/4ml) obtained from bacterial fermentation with high molecular weight.
Study: NCT04591834

Intervention type: OTHER
Intervention: Observational
Description: An observational study in subjects with the severe form of MPS II.