TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05625685

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quitbuddy
Description: Participants will be mailed a one week supply of nicotine lozenges as nicotine replacement therapy (NRT) for their upcoming quit attempt, with the ability to order more as needed. Participants will have a set Target Quit Date (TQD) set on Day 8 after enrollment, following one week of ad-lib smoking that comprises the pre-TQD EMA/GPS smoking data collection. GPS guided NRT usage prompts, via hotspot algorithms, will be provided to participants in the Quitbuddy Arm. Participants will contribute four weeks of post-TQD EMA/GPS data to capture lapses and NRT use in real-time. Carbon Monoxide (CO) levels will be tested at each of the six post-TQD remote assessments to provide objective verification of smoking status (i.e., 1 day, 1 week, 1 month, 2 month, 3 month, and 6 month abstinence rates). Computerized data collection methods (RedCap) will be used throughout the study to optimize quality assurance.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants will be mailed a one week supply of nicotine lozenges as nicotine replacement therapy (NRT) for their upcoming quit attempt, with the ability to order more as needed. Participants will have a set Target Quit Date (TQD) set on Day 8 after enrollment, following one week of ad-lib smoking that comprises the pre-TQD smoking data collection. Participants will contribute four weeks of post-TQD data to capture lapses and NRT use. CO levels will be tested at each of the six post-TQD remote assessments to provide objective verification of smoking status (i.e., 1 day, 1 week, 1 month, 2 month, 3 month, and 6 month abstinence rates). Computerized data collection methods (RedCap) will be used throughout the study to optimize quality assurance.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SDoH Augmentation
Description: The SDoH intervention is based on the findhelp.org online platform, with customization to meet the specific needs of the study and communities being served: includes validated SDoH assessments, personalized social needs searching based on priorities, access to the most comprehensive social service database, and a streamlined closed loop referral system that integrates with workflows.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SDoH Augmentation
Description: The SDoH intervention is based on the findhelp.org online platform, with customization to meet the specific needs of the study and communities being served: includes validated SDoH assessments, personalized social needs searching based on priorities, access to the most comprehensive social service database, and a streamlined closed loop referral system that integrates with workflows.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SDoH Control
Description: No SDoH intervention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SDoH Control
Description: No SDoH intervention
Study: NCT04986839

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paracetamol injection
Description: Intravenous Paracetamol

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuprofen injection
Description: Intravenous Ibuprofen
Study: NCT04718779

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Engagement Application (GD App)
Description: This is a chart review (prospective) data analysis study to describe the effect of the treatment change on the clinical parameters and patient reported outcomes (PROs) with the use of a digital engagement application (GD app) (to evaluate participants clinical engagement, shared decision making, emotional wellbeing, activities of daily living, goal attainment and Gaucher Disease specific measures).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No Intervention
Description: This is a chart review (retrospective) data analysis study to describe the effect of the treatment change on the clinical parameters.
Study: NCT06263127

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: oral stimulation
Description: Prefeeding OS is a 5-minute oral sensorimotor intervention, containing peri- and intra-oral stimulation for 3 minutes and pacifier sucking for 2 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: oral stimulation
Description: Prefeeding OS is a 5-minute oral sensorimotor intervention, containing peri- and intra-oral stimulation for 3 minutes and pacifier sucking for 2 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: infants massage
Description: IM is a 15-minute intervention, involving 5-min manual stroking on the infant's head, neck, back, upper limbs, and lower limbs twice and 5-min gentle flexion and extension exercises on the infant's arms and legs.
Study: NCT06182891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dulaglutide Injection
Description: Dulaglutide injection was injected subcutaneously at standard dose and frequency for consecutive 12 months in patients with type 2 diabetes and diabetic kidney disease. Other hypoglycemic agents not including GLP-1 receptor agonists were used at standard dose and frequency for consecutive 12 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dulaglutide Injection
Description: Dulaglutide injection was injected subcutaneously at standard dose and frequency for consecutive 12 months in patients with type 2 diabetes and diabetic kidney disease. Other hypoglycemic agents not including GLP-1 receptor agonists were used at standard dose and frequency for consecutive 12 months.
Study: NCT06525714

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cisplatin oxaliplatin tegafur
Description: Within 48 hours postoperative, the first infusion was performed with 3000-4000 ml of saline and 50 mg/m2 cisplatin at 43°C, with an infusion rate of 600 ml/min for a duration of 2 hours. During treatment, close attention is given to the patient's heart rate, blood pressure, oxygenation, and other vital signs. A total of 2 HIPEC treatments were conducted, each 48 hours apart. Systemic chemotherapy is initiated 3-4 weeks postoperative for 6-8 cycles using SOX: intravenous injection of oxaliplatin (130 mg/m2) on the first day and oral administration of tegafur (40-60 mg twice daily, with doses adjusted for body surface area: \<1.25 m2, 40 mg; 1.25m2 ≤ body surface area ≤ 1.5m2, 50mg; body surface area \>1.5m2, 60 mg bid) from day 1 to 14.
Study: NCT06065254

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Efficacy of free gingival grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness
Description: Two vertical incisions will be made in the previously elevated flap against the placed implant , where these two incisions will be 10 mm apart from each other, and the free graft to will be placed in this distance (10 x 10 mm). The graft will be obtained from the donor site (the hard palate), and will be thinned to obtain a regular graft with the required thickness. After that, the graft will be moved to its correct place accurately, while avoiding leaving a distance between the graft and the tissue underneath, and the graft will be sutured well to ensure its stability and correct placement.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Efficacy of connective tissue grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness
Description: Vertical incisions will not be made in the previously elevated flap against the placed implant, where there is no need to suture the flap apically of the grafting place because the graft will be covered with it after fixing it in place. The area will be washed with the serum to remove the clot before fixing the graft.The graft will be obtained from the donor site according to the previously mentioned method. Then the epithelium will be removed to leave the connective tissue underneath, and then the graft will be moved to its place (buccally dental implant site) and the flap will be sutured over it.

Intervention type: OTHER
Group type: OTHER
Intervention: No types of grafts will be made to improve the quality of the peri-implant mucosa
Description: The simple suturing of the two surgical incisions will be done after the completion of the dental implant process, with no procedure will be made to improve the quality of the peri-implant mucosa.
Study: NCT05356221

Intervention type: DEVICE
Intervention: Ponto Sound processor
Description: Bone Anchored Hearing solution fitted to compensate for the subjects hearing loss
Study: NCT05765877

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: WX-0593 Tablets
Description: 60 mg of WX-0593 tablets, once daily for 7 days, followed by 180 mg of WX-0593 tablets, once daily in a 28-days cycle.
Study: NCT05553405

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intralipid Infusion
Description: Intralipid 20% (a 20% IV fat emulsion) is a sterile, non-pyrogenic fat emulsion prepared for IV administration as a source of calories and essential fatty acids. It is made up of 20% soybean oil, 1.2% egg yolk phospholipids, 2.25% glycerin and water for injection. In addition, sodium hydroxide has been added to adjust the pH so that the final product pH is 8.
Study: NCT04830735

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dasatinib Anhydrous
Description: Given PO

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Administration
Description: Given PO
Study: NCT05691101

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CISB with IV PCA group
Description: Ultrasonography guided interscalene brachial plexus block was done with a 5 cm block needle and catheter was inserted. (Stimuplex®A, B Braun Medical, Bethlehem, PA). 10 mL 0.375 % ropivacaine was injected through the catheter.~0.2 % ropivacaine 4 ml/hour was injected through the continuous brachial plexus block catheter. IV-PCA with fentanyl (basal flow 0 ml with patient selected bolus 14 mcg, lockout 10 minutes) was started.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CISB group
Description: Ultrasonography guided interscalene brachial plexus block was done with a 5 cm block needle and catheter was inserted. (Stimuplex®A, B Braun Medical, Bethlehem, PA). 10 mL 0.375 % ropivacaine was injected through the catheter.~0.2 % ropivacaine (4 ml/hour with patient selected bolus 5 ml, lockout 60 minutes) was injected through the continuous brachial plexus block catheter.
Study: NCT05285748

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Paced Intensity Physical Activity
Description: Participants are given a prescription to engage in 150-300 minutes per week of structured exercise with an emphasis on walking. For this study arm, participants are given the explicit recommendation to engage in self-selected intensity PA.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prescribed Moderate Intensity Physical Activity
Description: Participants are given a prescription to engage in 150-300 minutes per week of structured exercise with an emphasis on walking. For this study arm, participants are given the explicit recommendation to engage in moderate intensity PA consistent with national guidelines.
Study: NCT01102023

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ordinary salt based- diet
Study: NCT05783934

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-florbetaben PET/CT
Description: The PET/CT study will be performed using a dual time acquisition protocol consisting of an early acquisition and a late acquisition.~Early acquisition Early acquisition starts with the patient already positioned on the PET/CT bed and venous access available.~A low-dose CT scan is performed for attenuation correction, the PET acquisition is started in list mode and a couple of seconds after the start, 300 MBq of 18F-Florbetaben is administered followed by washing with 10 ml of saline.~Early acquisition will last 30 minutes. Late acquisition A low-dose CT scan is performed to correct for attenuation and anatomical localisation, followed by a 20-minute list mode PET acquisition so that images are acquired after 90 minutes (tolerance: +10 minutes) of radiopharmaceutical uptake.
Study: NCT05333211

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ortho-R/PRP
Description: Ortho-R® is a freeze-dried drug/biologic combination product containing a chitosan component and trehalose, a disaccharide that acts as a lyoprotectant during the lyophilization process and calcium chloride, which acts as a PRP coagulation agent.
Study: NCT06472752

Intervention type: RADIATION
Intervention: Neoadjuvant radiotherapy
Description: Patients with a clear pathological diagnosis of high-risk UTUC were treated with a short course of 5 days of naSBRT: radiotherapy irradiation was directed to the primary lesion on the affected side and to the lymphatic drainage area, with a dose of 25 Gy (5 Gy\*5 days).The safety of the neoadjuvant radiotherapy dose and regimen can be evaluated by metrological ramping in the initial 5 patients, with subsequent patients following the optimal dose from ramping.

Intervention type: RADIATION
Intervention: Neoadjuvant radiotherapy
Description: Patients with a clear pathological diagnosis of high-risk UTUC were treated with a short course of 5 days of naSBRT: radiotherapy irradiation was directed to the primary lesion on the affected side and to the lymphatic drainage area, with a dose of 25 Gy (5 Gy\*5 days).The safety of the neoadjuvant radiotherapy dose and regimen can be evaluated by metrological ramping in the initial 5 patients, with subsequent patients following the optimal dose from ramping.

Intervention type: COMBINATION_PRODUCT
Intervention: Neoadjuvant drug therapy
Description: Patients will concurrently complete at least 2-4 cycles of preoperative neoadjuvant chemotherapy/immunotherapy/ADCs as well.
Study: NCT06325163

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CBCT
Description: Mandibular molar indicated for retreatment will be scanned using limited field of view CBCT to examine the number of canals

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: clinical examination under dental operating microscope
Description: the number of canals will be examined by an a randomly assigned operator following gutta percha removal under dental operating microscope

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: canal detection AI software (diagnocat)
Description: software used to analyze CBCT images and report the number of canals
Study: NCT06399601

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Drug allergy training program
Description: Two identical didactic courses on drug allergy were designed. Each course will last 12 hours and conducted over 2 consecutive days (6 hours each day). All candidates will attend physically and on-site. Various aspects of drug allergy with pre-set learning objectives will be taught in-person by instructors (physicians or nurses specializing in drug allergy nominated by the University of Hong Kong). Course materials and instructors will be identical for each course.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Drug allergy training program
Description: Two identical didactic courses on drug allergy were designed. Each course will last 12 hours and conducted over 2 consecutive days (6 hours each day). All candidates will attend physically and on-site. Various aspects of drug allergy with pre-set learning objectives will be taught in-person by instructors (physicians or nurses specializing in drug allergy nominated by the University of Hong Kong). Course materials and instructors will be identical for each course.
Study: NCT05802433

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D3 supplement
Description: 10µg vitamin D3 supplement per day for 90 days

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D3 supplement
Description: 10µg vitamin D3 supplement per day for 90 days

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D3 supplement
Description: 10µg vitamin D3 supplement per day for 90 days
Study: NCT06460259

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breathing Exercise
Description: He individual will be seated in a quiet environment in a semi-fowler or fowler position with their feet pointing forward. Then, they will be asked to join their hands on their abdomen and breathe normally while focusing on their breath. They will ensure their shoulders are relaxed, their body is loose, and they will inhale and exhale slowly and deeply through the nose without rushing.Next, while sitting upright with relaxed muscles, they will close their eyes, block their right nostril with their thumb or ring finger, inhale as much air as possible through the left nostril, and hold their breath. Then, they will block the left nostril with their ring finger or thumb and exhale slowly through the right nostril. The same process will be repeated for the left nostril. They will continue this process for approximately 2 minutes.
Study: NCT06273488

Intervention type: OTHER
Intervention: Auriculotherapy
Description: Treatment of pain, drug addictions, or other ailments by stimulating the various points on the external ear (EAR AURICLES). It is based on the ancient Chinese practices of EAR ACUPUNCTURE, but sometimes magnets and other modes of stimulation are used.
Study: NCT04702464

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fedratinib
Description: Fedratinib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluconazole
Description: Fluconazole
Study: NCT05224700

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: JAPI
Description: Each child will play on a tablet with headphones during 20 sessions lasting 30 minutes each, 2 times per week. All the activities are games with the following structure: an introduction with instructions and protagonist selection, followed by a practice exercise to ensure that the children understand what they have to do (the exercise is repeated until the child performs it correctly), and, finally, the activity itself (4 different activities with 5 tries each). The first 10 sessions jointly stimulate working memory and emotion knowledge (4 activities focused on each skill per session), while the 10 remaining sessions stimulate inhibitory control and the selection of prosocial behaviours. In the inhibitory control activities, they must suppress automatic stimuli and processes; in the emotion recognition activities, they must identify basic emotions; and in the selection of prosocial behaviours, they must choose an option to deal with a social problem.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Painting group
Description: Each child will play on a tablet with headphones during 20 sessions lasting 30 minutes each, 2 times per week. They will play a tablet-based painting game that involves no cognitive, emotional, or social competence stimulation
Study: NCT03962608

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Yaq-001
Description: Study patients will be dosed daily with 8g of product Yaq-001 for a period of 48 weeks. The product will be provided as beads packed in individual sachets intended each for one oral administration. For each patient, the study duration will be up to 54 weeks, including the screening (up to 45 days), treatment (48 weeks) and 7-day follow up period.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study patients will be dosed daily with a quantity of placebo equivalent to 8g of product Yaq-001 for a period of 48 weeks. The product will be provided as beads packed in individual sachets intended each for one oral administration. For each patient, the study duration will be up to 54 weeks, including the screening (up to 45 days), treatment (48 weeks) and 7-day follow up period.
Study: NCT05380765

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Native PATHS
Description: A strengths-based, behavioral economic approach to increasing engagement and reinforcement for engaging in alternative activities.
Study: NCT05064254

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as usual (TAU)
Description: TAU may include self-help methods, physician visit, provision of resources etc.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual (TAU)
Description: TAU may include self-help methods, physician visit, provision of resources etc.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindful Adaptive Practice in Pregnancy Therapy
Description: MAP teaches: a) recognition of personal maladaptive/ distressing patterns driving anxiety; b) how to relate differently; and c) cultivation of more adaptive ways of dealing with anxiety and learning how to effectively control it rapidly which allows re-engagement with life in more flexible ways.
Study: NCT05784051

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental group
Description: medical treatment including drug administration ± catheter ablation (Ablation can be performed if the PVC burden remain \>10% after 2 lines of AAD treatment).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: patients of this group have no therapeutic or no treatment modification such as drug therapy
Study: NCT06200935

Intervention type: DIETARY_SUPPLEMENT
Intervention: Probiotic blend
Description: Administration of one stick of combined probiotics per day for 5 months
Study: NCT05342896

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MIND diet
Description: MIND diet intervention will be a 3-month nutrition programme consisting of 4 face-to-face nutrition counselling sessions (one session per week, 60 min per session) in the activity room of each participating community centre. All intervention sessions will be conducted by a registered nutritionist and trained student helpers. In the nutrition sessions, the participants will learn to modify their diet to meet MIND diet guidelines.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mind diet plus Forest Bathing
Description: MIND diet intervention will be a 3-month nutrition programme consisting of 4 face-to-face nutrition counselling sessions (one session per week, 60 min per session) in the activity room of each participating community centre. All intervention sessions will be conducted by a registered nutritionist and trained student helpers. In the nutrition sessions, the participants will learn to modify their diet to meet MIND diet guidelines. Forest Bathing will be another session per week, 2 hours forest bathing sessions on 4-consecutive weekends in a country park at daytime with sunny, cloudy or drizzling conditions. The walking distance for each forest bathing is one to two kilometres. The coach-to-participant ratio is approximately 1:16. Participants will then be required to self-practice 2h FB in the country park at daytime at the weekends of 8th week and 12th week of the intervention.
Study: NCT05883696

Intervention type: OTHER
Intervention: Swedish Palliative Care Guide (S-PCG)
Description: S-PCG is a care guide that aim to inform best practice and to meet palliative care needs of patients and their families throughout all the time with palliative care needs. The S-PCG support palliative care for adult patients regardless of diagnosis, place of care and if it is early och late palliative care.~The S-PCG includes three parts~1. Assessments of palliative care needs~2. Initiating palliative care 2D. End of life care.~3. After death. In this study only the first part of the S-PCG will be used.