TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06664684

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Energy-restricted dietary intervention
Description: The diets were planned based on current guidelines, manuals, systematic reviews, and meta-analyses published in recent years on MAFLD \[5-6, 27-28\]. In this diet, carbohydrates constituted 50%-55% of total energy intake, proteins constituted 10%-20%, and fats constituted 25%-35%. The content of the diets was tailored to each patient, considering various factors such as sex, age, and physical activity status.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Energy + time-restricted dietary intervention
Description: Patients in the energy + time-restricted diet group followed the same dietary intervention and a 16:8 eating pattern where they were instructed to restrict their energy intake to an 8-h time window and not to consume energy-containing foods or drinks during the remaining 16 h. Participants were allowed to consume energy-free beverages such as water, coffee, and tea during fasting. The timing of the eating window during the day varied according to participants' lifestyles and habits. However, considering the importance of nocturnal fasting, the eating window in all patients started at 10:00-12:00 in the day and ended at 18:00-20:00 in the evening. The energy-restricted diet group did not follow any time restriction in the planning of main meals and snacks.
Study: NCT06662760

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3002 Tablets
Description: TQB3002 is a fourth-generation small molecule Epidermal growth factor receptor (EGFR) inhibitor, which inhibits relevant tyrosine kinase activity and intracellular phosphorylation process by competitively binding to Adenosine triphosphate (ATP) site of intracellular tyrosine kinase binding domain, thereby inhibiting EGFR downstream signaling, ultimately achieving the purpose of inhibiting tumor growth.
Study: NCT06664645

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: LHB tendon reinforcement
Description: complete repair with LHB tendon reinforcement

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: complete repair without reinforcement
Description: conventional rotator cuff complete repair without reinforcement
Study: NCT06662773

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3616 capsule + itraconazole
Description: C2/4/6 inhibitors + CYP3A metabolic enzyme inhibitors

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3616 capsule + rifampicin
Description: C2/4/6 inhibitors + Non-specific cytochrome P450 enzyme inducer
Study: NCT06664723

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high tone external muscle stimulation
Description: Device HiToP®: Parameters of (HTEMS), Voltage: 230-V Pulse widths: ≤350 mA. Electrical Frequency: Frequencies continuously scanned from 4096 Hz to 31768 Hz, allowing for a much higher power of up to 5000 m W. Intensity: the electrical stimulation will be adjusted to a pleasant level that will not produce any pain or discomfortable paraesthesia, Duration 30 minutes per session. Electrodes will be placed around ulcer. It will be introduced 3 times per week, for 8 weeks Prior to intervention, skin sensation will be assessed using warm water in a test-tube (temperature), pin prick (pain) and cotton wool (light touch) to ascertain the skin sensitivity
Study: NCT06543498

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Lactulose/Mannitol Ratio Test
Description: To test for gut permeability, Urine collected over 8hrs after ingestion of lactulose/mannitol drink.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Lactulose/Mannitol Ratio Test
Description: To test for gut permeability, Urine collected over 8hrs after ingestion of lactulose/mannitol drink.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Serum biomarkers of intestinal permeability
Description: Phlebotomy and subsequent lab tests to analyse concentration of LPS, LPB, sCD14, Zonulin and Occludin.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Serum biomarkers of intestinal permeability
Description: Phlebotomy and subsequent lab tests to analyse concentration of LPS, LPB, sCD14, Zonulin and Occludin.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rome IV questionnaire
Description: Diagnositic questionnaire for IBS-D

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Rome IV questionnaire
Description: Diagnositic questionnaire for IBS-D

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Irritable bowel severity scoring system
Description: Questionnaire to determine severity of abdominal and bowel symptoms
Study: NCT06664723

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard medical treatment (SMT)
Description: The Standard care of diabetic foot ulcers includes good glycemic control, adequate nutrition, off-loading (via bed rest or casts), local care (moist dressings and topical management), lessening of edema, surgical debridement of devitalized wound tissue and antibiotic therapy.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard medical treatment (SMT)
Description: The Standard care of diabetic foot ulcers includes good glycemic control, adequate nutrition, off-loading (via bed rest or casts), local care (moist dressings and topical management), lessening of edema, surgical debridement of devitalized wound tissue and antibiotic therapy.
Study: NCT06664164

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ANTERİOR QUADRATUS LUMBORUM BLOCK
Description: Patients are placed in the lateral decubitus position. The area where the block will be applied is disinfected with povidine iodine. A convex ultrasound probe is placed on the midaxillary line above the iliac crest. By visualizing the transverse process adjacent to the psoas major and quadratus lumborum muscles, using the in-plane technique, using a 22 gauge 80 mm peripheral block needle after negative aspiration into the anterior layer of the thoracolumbar fascia anterior to the quadratus lumborum muscle muscle, 0.5-1 ml of serum After observing hydrodissection with physiological, 20 ml of 0.25% bupivacaine is injected.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ANTERİOR QUADRATUS LUMBORUM BLOCK WİTH ADJUVANT
Description: Patients are placed in the lateral decubitus position. The area where the block will be applied is disinfected with povidine iodine. A convex ultrasound probe is placed on the midaxillary line above the iliac crest. By visualizing the transverse process adjacent to the psoas major and quadratus lumborum muscles, using the in-plane technique, using a 22 gauge 80 mm peripheral block needle after negative aspiration into the anterior layer of the thoracolumbar fascia anterior to the quadratus lumborum muscle muscle, 0.5-1 ml of serum After observing hydrodissection with physiological, 20 ml of 0.25% bupivacaine and 8 mg de-xamethasone are injected.
Study: NCT06662838

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ergonomics Awareness and First Aid Training Program
Description: The ergonomic awareness and first aid training program includes training on possible situations that children of seasonal agricultural worker families may encounter in the field.
Study: NCT06663215

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: School Based Bullying Prevention Program
Description: Three forms were administered to the adolescents: Personal Information Form, Bullying and Cyberbullying Scale for Adolescents (BCE-A) and Adolescent Future Expectations Scale. Adolescents were included in a school-based bullying prevention program the next day. One month later, the forms were administered again.
Study: NCT05747118

Intervention type: BEHAVIORAL
Intervention: Physical training
Description: A 12 week supervised training intervention with 1 hour physical training two times a week.
Study: NCT04286594

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD
Description: Participants will receive CBD solution during the open-label phase of the trial.
Study: NCT06664125

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX003002 will be administered orally
Description: tablets for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX003002 will be administered orally
Description: tablets for oral administration.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevelamer carbonate
Description: tablets for oral administration.
Study: NCT06663657

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive Sensorimotor Exercises
Description: Patients in group A will receive cognitive sensorimotor exercises for 30 minutes, sessions for 5 days per week for 8 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Task Oriented Training group
Description: Patients in group B will receive task oriented training for 30 minutes, sessions for 5 days per week for 8 weeks.
Study: NCT06664710

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iotaSOFT Insertion System with AIM
Description: Experimental subjects will receive the iotaSOFT Insertion System with AIM using robotic controlled stop

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iotaSOFT Insertion System with AIM Control
Description: iotaSOFT Insertion System with AIM using standard of care insertion techniques
Study: NCT06662955

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: audible cues
Description: Terminal knee extension exercise with audible cues

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Terminal knee extension exercise
Study: NCT06662877

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin-bound Paclitaxel + Tegafur Gimeracil Oteracil (S-1) + Anlotinib
Description: Albumin-bound Paclitaxel, 125mg/m2,iv.drip,d1,d8,Q3W +Tegafur Gimeracil Oteracil (S-1) 40-60mg,p.o,bid,d1-d14,Q3W+Anlotinib 10mg,p.o,d1-d14,Q3W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin + Leucovorin + Fluorouracil (FOLFOX regimen)
Description: Oxaliplatin 85 mg/m2,d1,iv.drip,Q2W + Leucovorin 400mg/m2,d1,iv.drip,Q2W+ Fluorouracil 2400 mg/m2 civ46h, Q2W
Study: NCT06156215

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vaccine Messaging
Description: 1. Video clips - short (approximately 3-minute) Public Service Announcement type videos to be viewed by participant using a QR code on their smartphone. If no smartphone is available, the video will be shown to the participant on an iPad.~2. Printed materials - one page information sheets handed to subjects by CRCs.~3. Face to face messaging - short (\< 1 minute), scripted message from the patient's providers in the ED (nurse or provider)~Each site will maintain a library of~A. 5 versions of the videos - the version used in any participant will be tailored to that participant's stated race/ethnicity.~B. 5 versions of printed flyers - likewise, the version will be tailored to the participant's stated race/ethnicity.~C. 1 version of scripted message to be delivered in English or Spanish.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaccine Acceptance Question
Description: The last question in the Vaccine Acceptance Survey in both the Intervention M and Intervention Q arms of the study is Would you accept the COVID-19 booster vaccine in the emergency department today if your doctor asked you?

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vaccine Acceptance Question
Description: The last question in the Vaccine Acceptance Survey in both the Intervention M and Intervention Q arms of the study is Would you accept the COVID-19 booster vaccine in the emergency department today if your doctor asked you?
Study: NCT04763772

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Body Fat Distribution Imaging Report
Description: Those randomized to body fat distribution imaging will be scanned on a 1.5 Tesla Siemens Aera MRI scanner (Siemens, Erlangen, Germany), located in the Center for Advanced Heart and Vascular Care using a 6-minute dual-echo Dixon Vibe protocol providing a water and fat separated volumetric data set covering neck to knees, and a multiecho Dixon acquisition for proton density fat fraction assessment in the liver. Images of the liver will be acquired using a 16-channel SENSE extra large Torso coil and images from the rest of the body will be acquired using the body coil. Volumetric imaging datasets of the body derived by MRI will be generated and adipose tissue/fat depots will be quantified: abdominal subcutaneous compartment (ASAT), visceral compartment (VAT), and hips and buttocks (lower body fat); proton density fat fraction of the liver (i.e. hepatic steatosis) as well as the quality of lean (skeletal muscle) including muscle volume and degree of fat infiltration.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Basic Weight Information
Description: Body weight and body mass index

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Provided
Description: Body weight/fat distribution information will be provided directly to the patient

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Physician Provided
Description: Body weight/fat distribution information will be provided directly to the physician
Study: NCT06543498

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Irritable bowel severity scoring system
Description: Questionnaire to determine severity of abdominal and bowel symptoms

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bowel Habit diary
Description: Assess bowel habit at baseline and changes in bowel habit over the study
Study: NCT04754581

Intervention type: OTHER
Group type: OTHER
Intervention: Maximal ATP Production (ATPmax)
Description: ATPmax will be measured in order to determine in vivo mitochondrial capacity. The magnetic resonance scans to measure mitochondrial energetics will also be performed.

Intervention type: OTHER
Group type: OTHER
Intervention: Exercise Testing (VO2max)
Description: Aerobic fitness level will be assessed while participant pedals on a stationary bicycle/walk on a treadmill. The volume of oxygen intake and carbon dioxide (CO2) production will be measured.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Muscle Biopsy
Description: Sample muscle cells from the left leg Vastus Lateralis (thigh) muscle.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Adipose Tissue Biopsy
Description: Sample fat tissue from the abdomen.

Intervention type: OTHER
Group type: OTHER
Intervention: Hyperinsulinemic euglycemic clamp
Description: Measurement of insulin sensitivity.

Intervention type: OTHER
Group type: OTHER
Intervention: PET imaging
Description: After an overnight fast, an intravenous catheter will be placed in each arm (one with arterial line for PET infusion, and the other for infusion of insulin, glucose, and 6,6 D2 glucose tracer. FDG-glucose will be injected followed by 90-minute PET scanning of the thigh.
Study: NCT06608069

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational counselling
Description: Enrolled participants will be counselled and educated by pharmacist on the therapy and benefits of adherence.
Study: NCT06270303

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Access flap & surgical debridement
Description: Following surgical exposure, roots are carefully debrided.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Access flap & surgical debridement
Description: Following surgical exposure, roots are carefully debrided.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Application of bone substitute material (BioOss Collagen)
Description: Following surgical debridement, the bone substitute material is applied to the furcation defect.
Study: NCT06311994

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Factors that may affect patient compliance with the VR-based intervention method to be applied to patients undergoing knee surgery and the factors that may affect the measurements to be performed were evaluated through a literature review and inclusion and exclusion criteria were created.
Study: NCT06632028

Intervention type: OTHER
Group type: OTHER
Intervention: artificial intelligence assisted spinal rehabilitation
Description: In artificial intelligence-based rehabilitation, it is more advantageous compared to other treatment methods in terms of the fact that technology applications can be designed according to the level and abilities of the individual and that the parameters such as duration, intensity, difficulty and speed of the treatment can be flexibly configured for the therapist and the patient.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: artificial intelligence assisted spinal rehabilitation
Description: In artificial intelligence-based rehabilitation, it is more advantageous compared to other treatment methods in terms of the fact that technology applications can be designed according to the level and abilities of the individual and that the parameters such as duration, intensity, difficulty and speed of the treatment can be flexibly configured for the therapist and the patient.

Intervention type: OTHER
Group type: OTHER
Intervention: conventional therapy
Description: In cervical disc herniation, non-invasive physical therapy applications such as laser treatment, hot-cold treatment methods, Transcutaneous Electrical Nerve Stimulation (TENS), interferential currents, manual therapy applications, kinesiological taping and exercise therapy, as well as painkillers and nonsteroidal anti-inflammatory drugs and antidepressive drugs are among the most preferred methods in treatment.(6)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: In cervical disc herniation, non-invasive physical therapy applications such as laser treatment, hot-cold treatment methods, Transcutaneous Electrical Nerve Stimulation (TENS), interferential currents, manual therapy applications, kinesiological taping and exercise therapy, as well as painkillers and nonsteroidal anti-inflammatory drugs and antidepressive drugs are among the most preferred methods in treatment.(6)
Study: NCT05932290

Intervention type: DRUG
Intervention: Elranatamab
Description: BCMA-CD3 bispecific antibody

Intervention type: DRUG
Intervention: Standard of care
Description: Standard of care
Study: NCT05694559

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Genetic Testing and Counseling
Description: Participants will complete testing

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Screening Form
Description: Participants will complete forms with demographics and history
Study: NCT05854290

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CRT
Description: Participants will complete an 8-week intervention, 2 sessions per week. Co-INTEGRATE sessions take 30-50 minutes to complete. Weekly on the day of the last therapy session, before or after the session, all patients, regardless of the group assigned to, will be asked to complete an electronic brief questionnaire to provide information, on sleep, recreational habits, alcohol intake, exercise, and smoking.
Study: NCT06543498

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Bowel Habit diary
Description: Assess bowel habit at baseline and changes in bowel habit over the study

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 3 day dietary record
Description: Used to verify compliance to exclusion criteria #5.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 3 day dietary record
Description: Used to verify compliance to exclusion criteria #5.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: NCT and NFT
Description: N-transcaffeoyltyramine and N-transferuloyltyramine supplement taken once per day.
Study: NCT05854290

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT
Description: Participants will complete an 8-week intervention, 2 sessions per week. Co-INTEGRATE sessions take 30-50 minutes to complete. Weekly on the day of the last therapy session, before or after the session, all patients, regardless of the group assigned to, will be asked to complete an electronic brief questionnaire to provide information, on sleep, recreational habits, alcohol intake, exercise, and smoking.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Modifiable lifestyle factors
Description: The therapy sessions are coupled with homework and requires some lifestyle modifications for the persons with MCI, such lifestyle adjustments are using a calendar, a diary, maintaining a sleep schedule and exercise.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care Psychoeducation
Description: Participants will receive 15-minute psychoeducation session twice per week for 8 weeks.~All research-related sessions will be web-based (on Zoom) and recorded (with approval).~Weekly on the day of the last therapy session, before or after the session, all patients, regardless of the group assigned to, will be asked to complete an electronic brief questionnaire to provide information, on sleep, recreational habits, alcohol intake, exercise, and smoking.
Study: NCT06508554

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Haptonomy
Description: 5. With the energy work, we will move on to the stage of harmonizing the intuitive and heart energy fields. It will be ensured that the mother's communication with her baby has a spiritual dimension as well as a physical one. 6. Then the stage of touching and communicating with the baby will begin. The hands of the researcher and the pregnant woman will be placed on the pregnant woman's uterus. Then, the pregnant woman will be the first to call her baby. This call to the baby will be repeated 2-3 times. 7. The pregnant woman and her uterus will be touched and exercises will be performed to adapt to the fetus. The aim is to increase the emotional awareness of the pregnant woman and to enable her to play intrauterine games with her baby (such as calling the baby, shaking her belly, moving the baby to the touched area with the mother's voice). Haptonomy will be completed with a deep relaxation exercise that will support the heart-uterus connection accompanied by breathing exercises.
Study: NCT06543498

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo supplement taken once per day.
Study: NCT05785299

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Cow's milk
Description: clinical introduction of cow's milk

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: clinical introduction of placebo

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Home introduction
Description: home introduction of cow's milk