TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04482920

Intervention type: DIAGNOSTIC_TEST
Intervention: p-aminohippurate clearance study
Description: To measure kidney blood flow, small doses of a substance called p-aminohippurate (PAH) are used.

Intervention type: DIAGNOSTIC_TEST
Intervention: p-aminohippurate clearance study
Description: To measure kidney blood flow, small doses of a substance called p-aminohippurate (PAH) are used.

Intervention type: DIAGNOSTIC_TEST
Intervention: Iohexol infusion
Description: To measure glomerular filtration rate (GFR)

Intervention type: DIAGNOSTIC_TEST
Intervention: Iohexol infusion
Description: To measure glomerular filtration rate (GFR)
Study: NCT04730947

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: 10 mg orally once a day

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Taken orally once a day, the placebo looks identical to the study drug but it contains no active ingredient
Study: NCT05074381

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling
Description: Dry needling (DN) is a myofascial treatment technique, in which a thin, solid filiform needle is inserted directly into the MTrP. During dry needling, local twitch responses (LTR) can be elicited. These are involuntary contractions of muscle fibers, leadi

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Needling
Description: During sham needling, a solid, filiform needle is inserted in the skin surface at the trigger point location, without penetrating the fascia and muscle tissue.
Study: NCT06070311

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Thymoquinone (0.5%) and Olive oil ointment
Description: Preparation of the Thymoquinone and Olive oil ointment:~Thymoquinone Oleaginous base ointment containing olive oil will be prepared for intranasal administration. The ointment will be prepared using the fusion method as follows:~Anhydrous lanolin and white soft paraffin will be melted at 70°C and then olive oil will be added with continuous stirring, Thymoquinone will be added to the congealing mixture as it is being cooled and stirred finally, the congealing mixture is left to cool at room temperature tell solidification and sterilized using UV radiation. The final product will be characterized for spreadability, drug content, drug release and stability.
Study: NCT04658680

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BCG vaccination at first health facility contact
Description: Intradermal injection at first health facility contact: 0.05 ml dose Mycobacterium bovis BCG live attenuated vaccine in the left deltoid region.~The strain supplied by the national vaccination programme is provided through UNICEF. Different strains are used interchangeably. The additional BCG vaccines provided through this study will be procured by the Bandim Health Project. Vaccines will be from the WHO list of prequalified vaccines and the same strain will be used in intervention and control health centres.
Study: NCT06392191

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Rhombic intercostal nerve block(Received liposomal bupivacaine 93 mg and bupivacaine 25 mg diluted to 20 ml)
Description: The patient was placed in lateral recumbency and placed medial to the medial border of the scapula in the oblique sagittal plane using a line array ultrasound probe to identify ultrasound landmarks, trapezius, obliques, intercostals, pleura, and lungs, The block needle was then entered in-plane at the T5 level, with the margins retracting on insertion, and the nerve block perforating needle was imaged and then inserted into the fascial gap between the trapezius and the external intercostal muscles. Receive liposomal bupivacaine 93 mg and bupivacaine 25 mg diluted to 20ml.
Study: NCT05843500

Intervention type: OTHER
Intervention: Survey
Description: Patients who received medical, surgical or interventional treatment for chronic thromboembolic pulmonary hypertension will be followed and given quality of life questionnaires.
Study: NCT06052982

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Drainage
Description: At the end of the knee arthroplasty, a drain is placed or not at the surgical site depending on randomization result

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Drainage
Description: At the end of the knee arthroplasty, a drain is placed or not at the surgical site depending on randomization result
Study: NCT06392191

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Rhombic intercostal nerve block(Receive standard bupivacaine 105 mg diluted to 20 ml with dexamethasone 5 mg.)
Description: The patient was placed in lateral recumbency and placed medial to the medial border of the scapula in the oblique sagittal plane using a line array ultrasound probe to identify ultrasound landmarks, trapezius, obliques, intercostals, pleura, and lungs, The block needle was then entered in-plane at the T5 level, with the margins retracting on insertion, and the nerve block perforating needle was imaged and then inserted into the fascial gap between the trapezius and the external intercostal muscles. A mixture of standard bupivacaine 105 mg diluted to 20 ml with dexamethasone 5 mg was received.
Study: NCT04479735

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Goggles
Description: Virtual reality goggles will placed at least 2 min prior to venipuncture to deteremine if it mitigates perceived anxiety or perceived pain scores.
Study: NCT06293391

Intervention type: PROCEDURE
Intervention: cardiac indices in supine and trendelenburg position
Description: Cardiac indices in supine and trendelenburg position in patients undergoing open or laparoscopic major cancer surgery

Intervention type: PROCEDURE
Intervention: cardiac indices in supine and trendelenburg position
Description: Cardiac indices in supine and trendelenburg position in patients undergoing open or laparoscopic major cancer surgery
Study: NCT06190990

Intervention type: OTHER
Group type: OTHER
Intervention: Otago Exercise + Exer gaming
Description: In this group the participant will receive otago exercises and exer-gaming based exercises. The duration of each session this group will receive is of 60 minutes A total of 12 sessions will be held, 3 times a week for 4 weeks. Reading will be taken on baseline, after 2 week

Intervention type: OTHER
Group type: OTHER
Intervention: exer gaming based programme
Description: In this group the participant will receive exer-gaming based exercises. The duration of each session this group will receive is of 60 minutes A total of 12 sessions will be held, 3 times a week for 4 weeks. Reading will be taken on baseline, after 2 weeks and then after 4 weeks.
Study: NCT05646173

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: vagus stimülation device
Description: Vagustim is a wearable medical technology device that focuses on non-invasive bilateral auricular vagus nerve stimulation (VNS). VNS is a clinically approved, safe and effective neuromodulation method.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electrophysical agents
Description: Electrophysical agents (EPAs) are those modalities that administer thermal, mechanical, electrical or light energy to the patient to provide physiological effects and therapeutic benefits.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: home exercise program
Description: The home exercise program will be explained to the patients by the physiotherapist and will also be given to the patient in the form of a brochure. Patients will be instructed to do the exercises regularly, three times a day for ten repetitions each day. The content of the exercises is updated weekly.
Study: NCT05363982

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial Photobiomodulation (tPBM)
Description: Transcranial Photobiomodulation (tPBM) is a novel treatment approach based on application of an invisible, non-ionizing electromagnetic wave that results in metabolic modulation in tissues targeted. This intervention consists of exposing bilaterally the frontal brain to the electromagnetic wave that penetrates the skin and skull into brain tissue, is non-invasive and minimally dissipated as thermal energy.~Other Names:~Niraxx G1 Headband

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Placebo/ Sham
Description: The sham treatment will consist of applying all the procedures for the delivery of tPBM, but will not deliver light.
Study: NCT05646173

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: home exercise program
Description: The home exercise program will be explained to the patients by the physiotherapist and will also be given to the patient in the form of a brochure. Patients will be instructed to do the exercises regularly, three times a day for ten repetitions each day. The content of the exercises is updated weekly.
Study: NCT06102343

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alma Harmony
Description: Acne scars treatment using non-ablative ER:Glass 1540 nm laser module.
Study: NCT06230562

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: The intervention is to take a blood sample every 6 months for 1 year which is not part of health routine care

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood sample
Description: The intervention is to take a blood sample at baseline.
Study: NCT05582031

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Regorafenib in combination with Tislelizumab
Description: Regorafenib 30 mg/tablet + Tislelizumab 100 mg/10 ml vial
Study: NCT05205434

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Synchronous telerehabilitation programme
Description: Exercise program and educational program

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Asynchronous telerehabilitation programme
Description: Exercise program educational program
Study: NCT06564480

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MI-R1 lower limb walking machine assisted training device
Description: The training is conducted under partial weight support training conditions, performing passive movements on the lower limbs through motor drive, improving the joint activity of the patient's hip and knee joints, and achieving sitting, standing, and walking functions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walking rehabilitation training under the guidance of therapists
Description: Each patient undergoes training under the guidance of a rehabilitation therapist
Study: NCT05708586

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: This is the control condition and anxiety is addressed in a standard way of having the care taker calm the child during the intervention.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality (VR)
Description: The child who is undergoing a procedure uses VR as a distraction during the intervention
Study: NCT04666480

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcatheter mitral valve repair
Description: Transvenous approach with a transeptal puncture to place the study device
Study: NCT04951804

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: EUS-CPN without bupivacaine
Description: Under conscious sedation, an echoendoscope is advanced into the stomach, just distal to the gastro-esophageal junction. The region of the celiac plexus is identified around the takeoff of the celiac artery from the aorta. Then, under real-time ultrasound guidance, a 19g needle is used to inject a neurolytic agent such as absolute alcohol around the base of the celiac artery.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: EUS-CPN with bupivacaine
Description: Under conscious sedation, an echoendoscope is advanced into the stomach, just distal to the gastro-esophageal junction. The region of the celiac plexus is identified around the takeoff of the celiac artery from the aorta. Then, under real-time ultrasound guidance, a 19g needle is used to firstly inject bupivacaine and secondly a neurolytic agent such as absolute alcohol around the base of the celiac artery.
Study: NCT05601037

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Axilla dissection + Lymphovenous anastomosis
Description: surgical bypass between lymphatic vessel and vein
Study: NCT05584332

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Quadrivalent Human Papillomavirus (Types 6, 11, 16, and 18) Recombinant Vaccine (Hansenula Polymorpha)
Description: 0.5 ml injection in 3 dosing regimen

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.5 ml injection in 3 dosing regimen
Study: NCT02772120

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal progesterone gel (Crinone® 8%)
Description: Crinone® 8% (90 mg of micronized progesterone in a bioadhesive vaginal gel contained in a single use, one piece applicator) is administered once 5 days prior to embryo transfer, then twice per day until the pregnancy test is negative or until the 10th week of pregnancy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intramuscular Progesterone
Description: Progesterone-25 mg intramuscularly once 5 days prior to embryo transfer, then 50 mg once per day until the pregnancy test is negative or until the 10th week of pregnancy.
Study: NCT05845892

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stress ball
Description: The use of the stress ball by the experimental group patients will be reminded by a hemodialysis nurse who was not involved in the study.
Study: NCT05384548

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problematic smart phone use course
Description: A 6 session, online, group-based, psychological course targetting problematic smart phone use.
Study: NCT04054180

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CPAP associated with connected devices: blood pressure monitor , scales and activity monitor
Description: CPAP associated with connected devices: blood pressure monitor , PROMs and activity monitor Patients will use their connected devices for one year. Data from the connected devices will be transmitted to their smartphone application Sefam Access. At the beginning of the study, patients will have a dietary assessment and start a support program for nutrition counselling and physical activity. At each study visit the dietician and physical exercise coach will give the patient advices on diet and for adjusting physical activity.
Study: NCT05665452

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Patellar mobilization, retinacula release, deep friction message, stretch and strength
Description: All exercises will be performed for 30 to 45 minutes per session, 3 times per week for 4 weeks (12 sessions). Group (1): stretch exercises are performed for calf, hamstring, iliotibial band and quadriceps. strength exercises consist from open kinetic chain (hip abductors, hip external rotators and quadriceps) and closed kinetic chain exercises (mini wall squat exercise, forward step up exercise, lateral step up exercise and terminal knee extension exercise).~Group (2): stretch exercises are performed for calf, hamstring, iliotibial band and quadriceps. strength exercises consist from open kinetic chain (hip abductors, hip external rotators and quadriceps) and closed kinetic chain exercises (mini wall squat exercise, forward step up exercise, lateral step up exercise and terminal knee extension exercise). manual therapy consists from iliotibial band release, deep friction message for lateral retinacula and medial patella mobilization.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patellar mobilization, retinacula release, deep friction message, stretch and strength
Description: All exercises will be performed for 30 to 45 minutes per session, 3 times per week for 4 weeks (12 sessions). Group (1): stretch exercises are performed for calf, hamstring, iliotibial band and quadriceps. strength exercises consist from open kinetic chain (hip abductors, hip external rotators and quadriceps) and closed kinetic chain exercises (mini wall squat exercise, forward step up exercise, lateral step up exercise and terminal knee extension exercise).~Group (2): stretch exercises are performed for calf, hamstring, iliotibial band and quadriceps. strength exercises consist from open kinetic chain (hip abductors, hip external rotators and quadriceps) and closed kinetic chain exercises (mini wall squat exercise, forward step up exercise, lateral step up exercise and terminal knee extension exercise). manual therapy consists from iliotibial band release, deep friction message for lateral retinacula and medial patella mobilization.
Study: NCT02758730

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AFFITOPE® PD01A + Adjuvant
Description: s.c. injection

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Adjuvant without active component
Description: s.c. injection
Study: NCT05545527

Intervention type: DRUG
Intervention: Ferric carboxymaltose
Description: As part of the RAPIDIRON Trial, maternal participants randomized to intervention arm 1 were given a single dose of ferric carboxymaltose between 14 and 17 weeks of pregnancy.

Intervention type: DRUG
Intervention: Iron isomaltoside
Description: As part of the RAPIDIRON Trial, maternal participants randomized to intervention arm 2 were given a single dose of iron isomaltoside between 14 and 17 weeks of pregnancy.

Intervention type: DRUG
Intervention: Ferric Sulfate
Description: As part of the RAPIDIRON Trial, maternal participants randomized to the active comparator arm were given 200 ferrous sulfate tablets immediately after randomization (\~12 weeks of pregnancy). Participants were instructed to take two tablets a day, with each tablet containing 60mg elemental iron.
Study: NCT06478524

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Live music
Description: Patients will have baseline data collection in the first week, followed by live music sessions and data collection during dialysis in the second week. The live music will be played for 45 minutes to one hour per dialysis session, and will be played during each of patients' three dialysis sessions in week 2 of this arm of the study.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pre-recorded music
Description: Patients will have baseline data collection in the first week, followed by pre-recorded music sessions and data collection during dialysis in the second week. The pre-recorded music will be played for 45 minutes to one hour per dialysis session, and will be played during each of patients' three dialysis sessions in week 2 of this arm of the study.
Study: NCT06232954

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mossie-Go containing treated transfluthrin disc
Description: The Mossie-GO repellent device is approximately 8 cm3 and can be fitted with repellent discs impregnated with transfluthrin and a carrier oil. These discs sit above a fan that is powered by a small motor charged by solar energy. The device is expected to both prevent bites and cause some mortality to mosquitoes when switched on for 8-12 hours overnight for up to 1 calendar month. The discs then need to be replaced.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Mossie-Go containing untreated blank disc
Description: The Mossie-GO repellent device is approximately 8 cm3 and can be fitted with a blank untreated disc. These discs sit above a fan that is powered by a small motor charged by solar energy. The device containing the untreated disc is not expected to prevent mosquito bites. The discs will still be replaced monthly for blinding purposes.
Study: NCT06634615

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR patient education video
Description: The educational video is created by converting the information provided by the service nurses into a video when the patient is admitted to the ward for surgery. The video will show a 2-3 minute animation of a nurse giving information. In a patient room, the service nurse will come to the newly admitted patient and explain the concept of cholecystectomy, the reasons for removing the gallbladder, how laparoscopic cholecystectomy is performed, the advantages of laparoscopic surgery compared to open surgery, the preparation process before and on the day of surgery, the conditions to be monitored after surgery, the importance of nutrition and fluid intake, defecation, the importance of early mobilization and discharge.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR patient education video
Description: The educational video is created by converting the information provided by the service nurses into a video when the patient is admitted to the ward for surgery. The video will show a 2-3 minute animation of a nurse giving information. In a patient room, the service nurse will come to the newly admitted patient and explain the concept of cholecystectomy, the reasons for removing the gallbladder, how laparoscopic cholecystectomy is performed, the advantages of laparoscopic surgery compared to open surgery, the preparation process before and on the day of surgery, the conditions to be monitored after surgery, the importance of nutrition and fluid intake, defecation, the importance of early mobilization and discharge.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR family interview
Description: Patients will have a 5-minute video call with their families in a 360° designed home environment using virtual reality glasses in the operating room waiting area.