Study: NCT06207942

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feed back controlled temperature device
Description: If core temperature exceeds 37.7 degrees celsius a feedback controlled-device will be used at set to 37.5 degrees celsius

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feed back controlled temperature device
Description: If core temperature exceeds 37.7 degrees celsius a feedback controlled-device will be used at set to 37.5 degrees celsius

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feed back controlled temperature device
Description: If core temperature exceeds 37.7 degrees celsius a feedback controlled-device will be used at set to 37.5 degrees celsius

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feed back controlled temperature device
Description: If core temperature exceeds 37.7 degrees celsius a feedback controlled-device will be used at set to 37.5 degrees celsius

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A mean arterial blood pressure (MAP) of \>85mmHg will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A mean arterial blood pressure (MAP) of \>85mmHg will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A mean arterial blood pressure (MAP) of \>85mmHg will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A mean arterial blood pressure (MAP) of \>85mmHg will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the intensive care unit without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the intensive care unit without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the intensive care unit without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the intensive care unit without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A mean arterial blood pressure (MAP) of \>65mmHG will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A mean arterial blood pressure (MAP) of \>65mmHG will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A mean arterial blood pressure (MAP) of \>65mmHG will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A mean arterial blood pressure (MAP) of \>65mmHG will be used. Vasopressors will be titrated to this target during 36 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the intensive care unit, used only as needed to facilitate transport, imaging and invasive procedures

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the intensive care unit, used only as needed to facilitate transport, imaging and invasive procedures

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the intensive care unit, used only as needed to facilitate transport, imaging and invasive procedures

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the intensive care unit, used only as needed to facilitate transport, imaging and invasive procedures