TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04105790

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy with Mindfulness classes
Description: The standard CBTm protocol is comprised of four 90-minute classes offered virtually via videoconferencing once a week for four consecutive weeks. The classes cover topics including mindfulness, cognitive therapy principles, behaviour therapy principles, managing anger, assertiveness, problem solving, goal setting, and evidence-based self-help resources. They are lecture-based but also involve experiential elements, such as mindfulness activities and practice of cognitive therapy strategies. Participants are assigned daily homework between each class to practice the strategies taught in session.
Study: NCT04840979

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 11C-ER176
Description: 11C-ER176 is a novel TSPO radioligand that was developed because of its relative insensitivity to the rs6971 polymorphism. Increased TSPO signal on PET is associated with activation of microglia in the brain. The radioligand will be administered in tracer doses at activity of up to 20 mCi (740 MBq), IV, total of one injection. A single dose of radioligand will be injected over 1 minute.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 11C-ER176
Description: 11C-ER176 is a novel TSPO radioligand that was developed because of its relative insensitivity to the rs6971 polymorphism. Increased TSPO signal on PET is associated with activation of microglia in the brain. The radioligand will be administered in tracer doses at activity of up to 20 mCi (740 MBq), IV, total of one injection. A single dose of radioligand will be injected over 1 minute.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-florbetaben
Description: Florbetaben has been approved by the FDA to help diagnose Alzheimer's disease. Florbetaben measures amyloid in the brain.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 18F-florbetaben
Description: Florbetaben has been approved by the FDA to help diagnose Alzheimer's disease. Florbetaben measures amyloid in the brain.
Study: NCT05520281

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Short-term psychodynamic psychotherapy for patients with serious physical illness (ORPHYS)
Description: A short-term psychodynamic therapy that focuses on the special inner and outer situation of patients with a serious physical illness, especially with regard to the importance of relationships in a limited lifetime.
Study: NCT05969769

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic Sustained Natural Apophyseal Glides
Description: Sustained Natural Apophyseal Glides 3 sets of 10 reps with 1 min rest btw sets.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscle Energy Techniques
Description: Short wave diathermy for 10 to 15 mins Muscle Energy Techniques of following muscles will be performed, Hip flexors muscles, Quadrates lamborum muscles, Erector spinae muscles, Piriformis muscles, PFS technique of METs Isometric hold 5-7 sec, Stretching 15 sec, Rest 30 sec.
Study: NCT05390242

Intervention type: DIAGNOSTIC_TEST
Intervention: Radiographic study
Description: Candidates undergo a radiographic study (Orthopantomography and Implant periapical radiography)

Intervention type: DIAGNOSTIC_TEST
Intervention: Radiographic study
Description: Candidates undergo a radiographic study (Orthopantomography and Implant periapical radiography)
Study: NCT06030232

Intervention type: DEVICE
Intervention: Therasphere
Description: Transarterial radioembolization
Study: NCT05040204

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Monosaccharide Powder
Description: Monosaccharide powder dissolved in water.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Monosaccharide Powder
Description: Monosaccharide powder dissolved in water.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Monosaccharide Powder
Description: Monosaccharide powder dissolved in water.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator
Description: Placebo (glucose powder)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator
Description: Placebo (glucose powder)
Study: NCT05318924

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ghrelin
Description: Participants will receive an infusion that is intended to raise ghrelin level up to a steady plateau.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive a saline infusion as the placebo control condition.
Study: NCT06202560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tofacitinib 5 MG
Description: Participants in the research will receive oral Tofacitinib medication with a dosage of 5 mg, twice a day, for 12 weeks. They will be scheduled to come for follow-up every 4 weeks throughout the 12-week period, and will continue to be followed up for 4 weeks after stopping the medication. The total duration of the research will be 16 weeks. The purpose is to evaluate the effectiveness and safety of the medication.
Study: NCT05233683

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caudal block
Description: Caudal block will be performed in lateral position with 0.25% bupivacaine in the dose of 0.75 ml/kg containing 1 mic/kg dexmedetomidine. The patients will be turned back to the supine position after the block placement and the head of the patient will be placed in the neutral position. Paracetamol suppository will also be inserted per rectum in the dose of 15 mg/kg before the start of surgery. The surgery will be started 10 minutes after block placement to allow adequate time for the block to be effective.
Study: NCT05215067

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: IV infusion,Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: IV infusion,Specified dose on specified days
Study: NCT05280925

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Episodic Future Thinking
Description: Participants will be prompted three times daily to think vividly about personally meaningful future events.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Information Thinking
Description: Participants will be prompted three times daily to think about their responses to informational health vignettes.
Study: NCT04712994

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PrEP Optimization Interventions
Description: A bundle of strategies (video-based PrEP counselling, HIV Self-Testing \[HIVST\] for women undergoing repeat HIV testing, and optimized PrEP delivery and prescription processes) will be implemented in the intervention group.
Study: NCT05852132

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pars plana vitrectomy(PPV)
Description: Vitrectomy was performed for severe non-proliferative diabetic retinopathy, but panretinal photocoagulation(PRP) was not performed

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pars plana vitrectomy(PPV) +Panretinal photocoagulation(PRP)
Description: PPV was performed for severe non-proliferative diabetic retinopathy with PRP.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Panretinal photocoagulation(PRP)
Description: Only PRP was used for severe non-proliferative diabetic retinopathy.
Study: NCT06491836

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: oligoantigenic diet
Description: Oligoantigenic diet that will cover recommended daily allowance (RDA) of macronutrients and micronutrients according patients' ages according to our available sources of food in our culture and the diet consists typically of meat (e.g. chicken and lamb), carbohydrate sources (e.g., potatoes and rice), fruits (e.g., bananas, pears and apples), vegetables (e.g., cucumbers, carrot, lettuce, cauliflower, turnips, cabbage and broccoli)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Food regimen without food restrictions.
Description: Food regimen that will cover recommended daily allowance (RDA) for macronutrients and micronutrients according patients' ages without any food restriction
Study: NCT06084910

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cultural Pride Reinforcement for Early School Readiness
Description: Cultural Pride Reinforcement for Early School Readiness (CPR4ESR) is based on the nationwide Reach Out and Read (ROR) program adapted to reinforce cultural pride. ROR provides children's books, brief book-sharing advice, and developmental surveillance at pediatric well child visits. Each of the 5 CPR4ESR sessions provides 1 children's book with a cultural pride theme, 1 parent handout, and modeling of book-sharing.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reach Out and Read
Description: ROR provides children's books and brief book-sharing advice at pediatric well child visits

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Reach Out and Read
Description: ROR provides children's books and brief book-sharing advice at pediatric well child visits
Study: NCT05644236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mouthwash
Description: After obtaining baseline information and randomizing the participants into two groups, dental scaling was performed, followed by clinical treatment. The participants were instructed to gargle twice daily for 7 days. All the participants were instructed not to eat or drink anything for at least 4 hours before the experiment. Oral hygiene, such as gargling and tooth brushing, was prohibited for 8 hrs before the visit.
Study: NCT05609721

Intervention type: OTHER
Intervention: no intervention, only observational study
Description: no intervention, only observational study

Intervention type: OTHER
Intervention: no intervention, only observational study
Description: no intervention, only observational study
Study: NCT05356598

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Authority-delivered Health promotion video
Description: A video delivered by a US Army Lieutenant Colonel (authority figure) encouraging participants to seek help for musculoskeletal injuries experienced while in ROTC.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peer-delivered Health Promotion Video
Description: A video delivered by a US Army ROTC cadet (peer) encouraging participants to seek help for musculoskeletal injuries experienced while in ROTC.

Intervention type: OTHER
Group type: OTHER
Intervention: Control Group Video
Description: Video of a US Army First Lieutenant squatting, bench pressing, and deadlifting with voiceover. No mention of musculoskeletal injuries or help-seeking behavior.
Study: NCT05233683

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caudal block
Description: Caudal block will be performed in lateral position with 0.25% bupivacaine in the dose of 0.75 ml/kg containing 1 mic/kg dexmedetomidine. The patients will be turned back to the supine position after the block placement and the head of the patient will be placed in the neutral position. Paracetamol suppository will also be inserted per rectum in the dose of 15 mg/kg before the start of surgery. The surgery will be started 10 minutes after block placement to allow adequate time for the block to be effective.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dorsal penile nerve block plus ring block
Description: It will be performed with the child in the supine position. Following skin preparation and palpation of the arch of the lower border of the symphysis pubis, the base of the penis will be gently pulled down, and a 25-G needle will be inserted at 10 and 2.0 O clock position to a depth of 0.25-0.5 cm (under Bucks' fascia) and 1 ml + 0.1ml X weight of the patient) of local anesthetic (0.25% bupivacaine) will be injected at each point after negative aspiration and then RB will be done in the form of a circumferential subcutaneous ring at the level of the base of the penis. Paracetamol suppository will also be inserted per rectum in the dose of 15 mg/kg before the start of surgery. The surgery will be started 10 minutes after block placement to allow adequate time for the block to be effective.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dorsal penile nerve block plus ring block
Description: It will be performed with the child in the supine position. Following skin preparation and palpation of the arch of the lower border of the symphysis pubis, the base of the penis will be gently pulled down, and a 25-G needle will be inserted at 10 and 2.0 O clock position to a depth of 0.25-0.5 cm (under Bucks' fascia) and 1 ml + 0.1ml X weight of the patient) of local anesthetic (0.25% bupivacaine) will be injected at each point after negative aspiration and then RB will be done in the form of a circumferential subcutaneous ring at the level of the base of the penis. Paracetamol suppository will also be inserted per rectum in the dose of 15 mg/kg before the start of surgery. The surgery will be started 10 minutes after block placement to allow adequate time for the block to be effective.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Circumcision with Plastibell
Description: Circumcision with Plastibell

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Circumcision with Plastibell
Description: Circumcision with Plastibell

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional Dissection Method
Description: Conventional Dissection Method

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Dissection Method
Description: Conventional Dissection Method
Study: NCT06601946

Intervention type: OTHER
Group type: OTHER
Intervention: BLS Paper Based Cognitive App
Description: BLS Paper Based Cognitive App

Intervention type: OTHER
Group type: OTHER
Intervention: First Aid App
Description: First Aid App

Intervention type: OTHER
Group type: OTHER
Intervention: Corpatch App
Description: Corpatch App
Study: NCT06659536

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Tibial Nerve Stimulation (TTNS) with the Cefar Uro Device
Description: Transcutaneous Tibial Nerve Stimulation (TTNS) with the Cefar URO device using the preset program P4 (parameter setting: frequency 20Hz, pulse width 200μs) for the symptomatic treatment of urge incontinence in adults with overactive bladder in accordance with the approved labelling.
Study: NCT06377371

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Brain Imaging with [Cu64]DOTATATE
Description: Patients will undergo a \[Cu64\]DOTATATE PET/MRI or PET/CT before undergoing radio- guided surgery. Patients will undergo another \[Cu64\]DOTATATE PET/MRI or PET/CT 6 weeks- 3 months after their surgery, and 6 months- 12 months after surgery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radio-guided Surgery With Neoprobe Utilization
Description: After the subjects undergo the preoperative \[Cu64\]DOTATATE PET/MRI, subjects will undergo radio-guided surgery in which the surgeon will utilize a standard intraoperative gamma probe (Neoprobe Gamma Detection System ®) to assess primary/residual tumor detection.
Study: NCT05033301

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nurse Ned Clinic
Description: Participants enrolled in the Nurse-led Ned Clinic will receive virtual PCa survivorship follow-up care from both their specialist and an oncology nurse for one year.
Study: NCT06665893

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digi-physical treatment tool
Description: A support tool named Evira will be used to provide behavioral treatment. Through daily weightings at home using a special designed scale, which sends data directly to an application on the parents phone and to a clinic homepage, the child's weight development can be easily monitored.
Study: NCT06667713

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ENTRUST - substance use and HIV counseling and goal setting with economic empowerment and photovoice training
Description: The ENTRUST intervention consists of an adapted counseling intervention based on motivational interviewing techniques and goal setting (SBIRT-T); Economic skill building using a tailored app (WorthIt for ENTRUST); and, Photovoice Activities with an optional photo exhibit

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SBIRT-T only
Description: An adapted screening brief intervention and referral to treatment intervention to link transgender women to substance use and HIV services
Study: NCT06667830

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical exercise program
Description: The physical exercise program will consist of exercises from three different exercise modalities: aerobic training, balance exercises, and isometric exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical exercise program
Description: The physical exercise program will consist of exercises from three different exercise modalities: aerobic training, balance exercises, and isometric exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neural mobilization techniques
Description: Neural mobilization techniques for the upper and lower quadrants will be actively performed by participants.
Study: NCT05579392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bright Light Therapy
Description: Device: Bright Light Therapy Retimer

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bright Light Therapy
Description: Device: Bright Light Therapy Retimer

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Placebo Retimer Device
Description: Device: Placebo Retimer Device with no bright light therapy

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Placebo Retimer Device
Description: Device: Placebo Retimer Device with no bright light therapy
Study: NCT06621290

Intervention type: OTHER
Intervention: Semi-structured interviews
Description: Semi-structured interviews on ED-patients experiences of frailty assessment with the CFS
Study: NCT06665360

Intervention type: OTHER
Intervention: The high speed bur was used to mill the cancellous cortical bone of the lamina
Description: The high speed bur was used to mill the cancellous cortical bone of the lamina
Study: NCT06681857

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sinus lifting
Description: The implant osteotomy will be initiated by pilot drill entries followed by sequential drills via the radiographic stent's sleeves to position the fixtures precisely into the pre-determined recipient sites. The Implant stability quotient (ISQ) will then be measured using an Osstell device after attaching intelligent implant pigs. Finally, the mucoperiosteal flaps will be sutured in place with 4-0 Prolene.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sinus lifting
Description: The implant osteotomy will be initiated by pilot drill entries followed by sequential drills via the radiographic stent's sleeves to position the fixtures precisely into the pre-determined recipient sites. The Implant stability quotient (ISQ) will then be measured using an Osstell device after attaching intelligent implant pigs. Finally, the mucoperiosteal flaps will be sutured in place with 4-0 Prolene.
Study: NCT06685393

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Platelet rich plasma (PRP)
Description: At the 1st visit, each quadrant is scaled and root planned using an ultrasonic scaler and manual instruments until tactile sensation detects smooth crown and root surfaces these procedures were repeated on both sides starting from 1st visit of treatment,2nd,4th, and 6th-week intervals local anesthetic was utilized in some instances where it was the necessary and subgingival application of (PRP) at test side only at baseline,3ed, 6th week.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Platelet rich plasma (PRP)
Description: At the 1st visit, each quadrant is scaled and root planned using an ultrasonic scaler and manual instruments until tactile sensation detects smooth crown and root surfaces these procedures were repeated on both sides starting from 1st visit of treatment,2nd,4th, and 6th-week intervals local anesthetic was utilized in some instances where it was the necessary and subgingival application of (PRP) at test side only at baseline,3ed, 6th week.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: INJECTABLE PLATELET RICH FIBRIN(I-PRF)
Description: At the 1st visit, each quadrant is scaled and root planned using an ultrasonic scaler and manual instruments until tactile sensation detects smooth crown and root surfaces these procedures were repeated on both sides starting from 1st visit of treatment,2nd,4th, and 6th-week intervals local anesthetic was utilized in some instances where it was the necessary and subgingival application of (I-PRF) at test side only at baseline,3ed, 6th week.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: INJECTABLE PLATELET RICH FIBRIN(I-PRF)
Description: At the 1st visit, each quadrant is scaled and root planned using an ultrasonic scaler and manual instruments until tactile sensation detects smooth crown and root surfaces these procedures were repeated on both sides starting from 1st visit of treatment,2nd,4th, and 6th-week intervals local anesthetic was utilized in some instances where it was the necessary and subgingival application of (I-PRF) at test side only at baseline,3ed, 6th week.
Study: NCT06682988

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirvetuximab Soravtansine
Description: intravenous (IV) infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirvetuximab Soravtansine
Description: intravenous (IV) infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirvetuximab Soravtansine
Description: intravenous (IV) infusion
Study: NCT06684158

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mecapegfilgrastim
Description: 6 mg,HD d3,every 2weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Adebrelimab：1200 mg，iv d1，every2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Adebrelimab：1200 mg，iv d1，every2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Docetaxel：50 mg/m2 iv gtt d1，every 2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Docetaxel：50 mg/m2 iv gtt d1，every 2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Oxaliplatin ：85 mg/m2 iv gtt d1，every2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Oxaliplatin ：85 mg/m2 iv gtt d1，every2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-Fluorouracil (5-FU)
Description: 5-FU ：2600 mg/m2 ，intravenous infusion， 24h ，d1，every 2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-Fluorouracil (5-FU)
Description: 5-FU ：2600 mg/m2 ，intravenous infusion， 24h ，d1，every 2 weeks (Q2W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin (LV)
Description: LV：200 mg/m2 iv gtt d1，every 2 weeks (Q2W)