TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04236999

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yo Sé Lo Que Quiero (YSLQQ)
Description: This program is organized in 12 sessions around three themes:~* Knowledge and attitudes (sessions 1, 3, 5 and 9): Students reflect on their knowledge of legal and illegal drugs, using critical thinking to obtain an objective assessment of this knowledge.~* Intrapersonal skills (sessions 4, 6, 8, 10. 11. and 12): Activities are carried out where students can put themselves in everyday situations and develop skills such as assertiveness, problem solving, among others.~* Interpersonal skills (sessions 2 and 7): Students are instructed to practice refusal skills, assertiveness, and analyze coping strategies.
Study: NCT06362382

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: tele-rehabilitation training
Description: During their stay in the hospital, the patients were accompanied by a rehabilitation trainer and a psychotherapist for a complete cycle of (7 days ± 3 days 1 week/times) standardized training.~After discharge from the hospital, patients in the rehabilitation group underwent 3-5 weekly daily （a total of 3 months）training sessions and intensive supervision and management by the online community at least once a week. All patients' routines were monitored by telemetry and data, photographs and video recordings were collected by a specialized agency.~The scheme of rehabilitation is impedance training. A specialized professional team including cardiologists, rehabilitation trainers, psychotherapists and radiologists were involved.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: health propaganda and education
Description: During their stay in the hospital, participants of the control group received health propaganda and education (7 days ± 3 days 1 week/times).~After discharge from the hospital, the control group followed their daily routine.
Study: NCT04209894

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: Evaluation consisted of the detection of grey scale (GS) enthesitis and Power Doppler signal in enthesis areas of participants. The Madrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: Evaluation consisted of the detection of grey scale (GS) enthesitis and Power Doppler signal in enthesis areas of participants. The Madrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities
Study: NCT04736563

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Joint and muscle gel Puressentiel
Description: To evaluate the antalgic effect in patients with chronic pain related to osteoarthritis of the knee when applied to the skin of Puressentiel Joints and Muscles - Gel with 14 essential oils.
Study: NCT05762159

Intervention type: OTHER
Intervention: data collected
Description: data collected:~* Morphological data of the patients~* Data of the erector block realization~* Pupillometric data :the variation of the pupil size on stimulation (in percentage of the base diameter)
Study: NCT06506656

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyadrol®
Description: Sterile single-use Medical Device for intra-articular injections
Study: NCT04707092

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotic
Description: Antibiotic in case of now allergies will be Cefazolin at induction and Amoxicillin plus Clavulanic acid for the oral treatment week

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotic
Description: Antibiotic in case of now allergies will be Cefazolin at induction and Amoxicillin plus Clavulanic acid for the oral treatment week
Study: NCT05309733

Intervention type: GENETIC
Intervention: VOR33
Description: VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell therapy product that lacks the CD33 myeloid protein.
Study: NCT05090618

Intervention type: GENETIC
Intervention: DNA analysis
Description: GWAS

Intervention type: GENETIC
Intervention: DNA analysis
Description: GWAS
Study: NCT05178186

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Thyroidectomy
Description: Surgery for thyroid carcinoma
Study: NCT06123481

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Core Decompression
Description: Standard core decompression procedure is performed by drilling into the necrotic bone of the femoral head. A sham bone marrow aspiration involves advancing a needle to the iliac crest (no bone penetration, no bone marrow aspiration) through a small skin incision.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Core Decompression
Description: Standard core decompression procedure is performed by drilling into the necrotic bone of the femoral head. A sham bone marrow aspiration involves advancing a needle to the iliac crest (no bone penetration, no bone marrow aspiration) through a small skin incision.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate
Description: This involves bone marrow aspiration, concentrating the bone marrow aspirate, and injecting 6 milliliters of bone marrow aspirate concentrate into the necrotic femoral head through an opening created by the core decompression.
Study: NCT06361134

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SAFE Early İntervention
Description: As part of the intervention, sensory-based intervention was applied in an enriched environment. In the home setting, physiotherapists collaborated with the family to advance the intervention. The intervention was revised by making monthly home visits to infants with a corrected age of 42 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SAFE Early İntervention
Description: As part of the intervention, sensory-based intervention was applied in an enriched environment. In the home setting, physiotherapists collaborated with the family to advance the intervention. The intervention was revised by making monthly home visits to infants with a corrected age of 42 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NDT based therapy
Description: Neuromotor evaluations of the babies were performed in a clinical setting. The rehabilitation program to be implemented was given to the family as a booklet. The programs of the children examined in the clinic every month were revised.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NDT based therapy
Description: Neuromotor evaluations of the babies were performed in a clinical setting. The rehabilitation program to be implemented was given to the family as a booklet. The programs of the children examined in the clinic every month were revised.
Study: NCT05365100

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID
Study: NCT04946565

Intervention type: DIAGNOSTIC_TEST
Intervention: Semen analysis
Description: Semen analysis according to WHO laboratory manual for the examination and processing of human semen, Fifth edition
Study: NCT05365100

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID
Study: NCT06176482

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic markers implantation
Description: Surgical implantation of magnetic markers in the upper limb stump to allow the management of an external hand prosthesis
Study: NCT05365100

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BN102
Description: oral tablets: BN102, BID
Study: NCT05874089

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: VSL#3®
Description: VSL#3® 450 billions/sachets

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo sachets with maltose, cornstarch and dioxide
Study: NCT05434819

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Atrial Fibrillation Ablation
Description: Surgeon will preform surgical atrial fibrillation ablation using either cryoablation or bipolar radiofrequency clamps including 2 layers of atrium or vein, a minimum of 2 burns per clamping with at least 3 lines in the ablation group. Cavo-tricuspid isthmus and mitral lines will be allowed.
Study: NCT05321485

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MedicijnWijs
Description: The mobile phone app MedicijnWijs will guide the participants with their azathioprine therapy during 6 weeks. Information about azathioprine is given as well as general information about IBD, specified to disease modality (Crohn's Disease and Ulcerative Colitis). Contact details of the patient's pharmacy are listed, questions about the patient's symptoms are asked, and push notifications are added to remind the patients to take their medication.~At the beginning of the 6-weeks guidance, two validated questionnaires that are translated and validated in Dutch will have to be filled in: the MARS-5 and the IBD-KID2. After 6 weeks, the participants have to fill out the same questionnaires again to assess potential changes in the scores compared to baseline. Also, a number of questions will be asked to assess the ease of use of MedicijnWijs.
Study: NCT05198882

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laser technology for intracerebral thermocoagulation
Description: One intervention : LITT (Laser Interstitial Thermal Treatment), technology that uses laser energy to thermally destroy (photo-thermal treatment) a brain injury under continuous MRI control (Validated by FDA - CE marking). The operator console + surgical laser generator + software that manages the power delivered by the laser is connected to an MRI - Provided by MEDTRONIC - FDA approved and CE certified.
Study: NCT05662917

Intervention type: BEHAVIORAL
Intervention: Individual semi-structured interviews
Description: After information and written consent, the investigator will interview the participants through a semi-structured individual interview (conducted by an interview guide). The interview is expected to last 45 minutes (variable depending on the subject). It will be recorded by dictaphone, respecting the anonymity of the participant throughout the interview. The subject's participation will end after the interview.
Study: NCT05161806

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOK583A1 (40 mg/mL)
Description: SOK583A1 provided in a Prefilled Syringe (PFS), which includes 2 mg aflibercept in 0.05 mL for IVT administration

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prefilled Syringe (PFS)
Description: Prefilled Syringe (PFS)
Study: NCT05958914

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic CGRP
Description: Immunoassay kit for the evaluation of CGRP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic CGRP
Description: Immunoassay kit for the evaluation of CGRP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic CGRP
Description: Immunoassay kit for the evaluation of CGRP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic SP
Description: Immunoassay kit for the evaluation of SP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic SP
Description: Immunoassay kit for the evaluation of SP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic SP
Description: Immunoassay kit for the evaluation of SP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic enkephalins
Description: Immunoassay kit for the evaluation of enkephalins in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic enkephalins
Description: Immunoassay kit for the evaluation of enkephalins in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic enkephalins
Description: Immunoassay kit for the evaluation of enkephalins in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic VIP
Description: Immunoassay kit for the evaluation of VIP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic VIP
Description: Immunoassay kit for the evaluation of VIP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of ematic VIP
Description: Immunoassay kit for the evaluation of VIP in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of CGRP in follicolar fluid
Description: Immunoassay kit for the evaluation of CGRP in follicolar fluid

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of CGRP in follicolar fluid
Description: Immunoassay kit for the evaluation of CGRP in follicolar fluid

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of SP in follicolar fluid
Description: Immunoassay kit for the evaluation of SP in follicolar fluid

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of SP in follicolar fluid
Description: Immunoassay kit for the evaluation of SP in follicolar fluid

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of enkephalins in follicolar fluid
Description: Immunoassay kit for the evaluation of enkephalins in follicolar fluid

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of enkephalins in follicolar fluid
Description: Immunoassay kit for the evaluation of enkephalins in follicolar fluid
Study: NCT03653169

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Magnetic Stimulation
Description: TMS is a form of noninvasive brain stimulation. An external electromagnetic coil is placed on the head, and a large current is passed through an insulated wire coil held flat on the surface of a subject's scalp in a fraction of a millisecond. This pulse of current induces a weak electrical current within the surface brain cortex. Repetitive trains of TMS pulses (repetitive TMS or rTMS) can transiently modulate corticospinal excitability following the rTMS train. When current is delivered at high frequency (10 Hz), it may simultaneously increase the activity of the brain at this site. In this study, individuals will receive 10 treatments with intermittent theta burst stimulation (twice daily for 5 days).
Study: NCT04277715

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent training
Description: Parents will learn evidence-based techniques for increasing support and decreasing accommodation of children's chronic symptoms.
Study: NCT01431586

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JDtic
Description: The planned JDTic dose levels to be evaluated are 1 mg, 3 mg, and 10 mg; however, the actual dose levels evaluated may be different, and/or additional dose levels may be added by protocol amendment, depending on the safety and PK results of the lower doses.~Subjects will be admitted to the clinic the day before dosing and will be confined to the clinic for 6 nights, with safety and PK evaluations and assessments lasting approximately 125 hours following administration of study drug.
Study: NCT04901936

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegcetacoplan
Description: Complement (C3) inhibitor
Study: NCT05174130

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RESPIRA device.com® Advanced
Description: Ventilation of patients with continuous monitoring of the patient's clinical parameters and the parameters that the investigational medical device shows.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RESPIRA device.com® Advanced
Description: Ventilation of patients with continuous monitoring of the patient's clinical parameters and the parameters that the investigational medical device shows.
Study: NCT05628493

Intervention type: BEHAVIORAL
Intervention: Gut microbiota Analysis
Description: fecal samples were collected per patient on days 1,3 and 7 after ICU admission. All eligible patients were given antibiotics therapy, actively control infection source by puncture drainage or surgery if necessary, as well as other supportive therapy to maintain organ function.

Intervention type: BEHAVIORAL
Intervention: Gut microbiota Analysis
Description: fecal samples were collected per patient on days 1,3 and 7 after ICU admission. All eligible patients were given antibiotics therapy, actively control infection source by puncture drainage or surgery if necessary, as well as other supportive therapy to maintain organ function.
Study: NCT05958914

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dosage of VIP in follicolar fluid
Description: Immunoassay kit for the evaluation of VIP in follicolar fluid
Study: NCT06159166

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirdametinib
Description: This study is designed to assess Mirdametinib safety and efficacy in two phases: phase 1 tests the safety of up to four dose regimens of Mirdametinib, administered continuously or intermittently (3 weeks on/1 week off) to identify up to two recommended phase 2 doses. Phase 2a of the study will test the safety and efficacy of the recommended phase 2 dose(s) in adults with NF1 and cNF. The following dosing strategy will be assessed in participants ≥ 18 years old with NF1 and a minimum of 12 measurable cNF who desire systemic treatment of their cNF due to disfigurement, pain or itching. Each treatment cycle in this study is 28 days.treatment cycle in this study is 28 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirdametinib
Description: This study is designed to assess Mirdametinib safety and efficacy in two phases: phase 1 tests the safety of up to four dose regimens of Mirdametinib, administered continuously or intermittently (3 weeks on/1 week off) to identify up to two recommended phase 2 doses. Phase 2a of the study will test the safety and efficacy of the recommended phase 2 dose(s) in adults with NF1 and cNF. The following dosing strategy will be assessed in participants ≥ 18 years old with NF1 and a minimum of 12 measurable cNF who desire systemic treatment of their cNF due to disfigurement, pain or itching. Each treatment cycle in this study is 28 days.treatment cycle in this study is 28 days.
Study: NCT05454722

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ADEX Gel
Description: Emollient Gel with added anti-inflammatory
Study: NCT05993507

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Management Plus (PM+)
Description: Problem Management Plus (PM+) is a brief, scalable intervention that is developed by World Health Organization for communities exposed to adversity. PM+ consists of five weekly in-person sessions of 90 minutes. The intervention integrates four evidence-based behavioural strategies: arousal reduction using a slow breathing exercise (session 1), problem-solving (session 2), behavioural activation by re-engaging with pleasant and task-oriented activities (session 3) and accessing social support (session 4). Homework practice is scheduled following each session and discussed in the next session. Psychoeducation is delivered in session 1 and relapse prevention is discussed in session 5. Facilitators will receive weekly supervisions by PM+ supervisors.
Study: NCT05978856

Intervention type: OTHER
Intervention: Accuracy of computer software in predicting soft tissue profile changes
Description: Separate analyses will be performed on the initial and final cephalograms.~* All of the cephalometric analyses will be done via computer software,the linear and angular measurements will be done via the software.~* Through the use of software, the initial cephalogram and the initial photograph will be linked.~* Then, the final values of some angles will be tracted from the post-treatment cephalogram.~* These values will be inserted in the treatment simulationsection of the software.~* A post-treatment projected image of the patient will be simulated by the software.~* Then the actual post-treatment photograph will be placed on the simulated image in transparent form.~* From the pupil , real horizontal and vertical reference lines will be drawn.~* Then certain measurements will be taken from referance lines to fixed points on the soft tissue to determine the discrepancies between the real and simulated images.
Study: NCT04779671

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR cognitive training
Description: All participants will receive trainings for 60 minutes per day, two days per week for 16 sessions.~They will receive one immersive leisure-based VR cognitive training for 30 minutes. VR cognitive training receives four gardening activities.~The cognitive elements including attention, working memory, processing speed, and executive function incorporated training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional cognitive training
Description: All participants will receive trainings for 60 minutes per day, two days per week for 16 sessions.~The control group is performing traditional cognitive training program.
Study: NCT05751057

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cardiovascular Magnetic Resonance
Description: All NSTEMI patients will undergo to CMR before invasive coronary intervention.
Study: NCT05331430

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry needling on cervical trigger point
Description: One experimental group will receive dry needling treatment on the upper trapezius fibres using the Hong technique and the other experimental group will receive passive muscle stretching treatment on the upper trapezius fibres.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry needling on cervical trigger point
Description: One experimental group will receive dry needling treatment on the upper trapezius fibres using the Hong technique and the other experimental group will receive passive muscle stretching treatment on the upper trapezius fibres.
Study: NCT04912882

Intervention type: DIAGNOSTIC_TEST
Intervention: Circulating tumor cell
Description: detecting circulating tumor cell pre- and post operatively

Intervention type: DIAGNOSTIC_TEST
Intervention: Circulating tumor cell
Description: detecting circulating tumor cell pre- and post operatively
Study: NCT04799678

Intervention type: OTHER
Intervention: Recording voice samples
Description: A maximum of 9 voice sample recording session will be carried out on their phones and take less than 2 minutes each
Study: NCT05715554

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Homeopathy
Description: Individualized homoeopathic medicines on impregnated lactose pellets was prescribed based on totality of physical, emotional, and mental symptoms.
Study: NCT06231719

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Spray
Description: Using cold spray for injection site before the Anti-D immunglobulin injection. 2 sprays of cold spray are applied from a distance of 25 cm.