TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04767334

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Anti-Gravity Treadmill
Description: Each participant will started with a 5 - 10 minute warm-up on a standard cycle ergometer, manual and therapeutic therapy for upper extremity, and gait training using LBPP. Manual and therapeutic therapy will consist of passive and active ROM, joint mobilization, passive and active stretch, manual resistance exercise, and activities of daily life (ADL). All participants will walk in Alter G one session a day (for 40 min), three days a week, for six weeks. On session one, the Alter G pressure chamber will be set to unload 50% of patient's body weight. On the following sessions, the percentage of unload patient's body weight will be decrease depends on the patient's comfort.~The physical therapist assistance and treadmill speed will be evaluated and altered based on the patient's capacity. The participants can take a rest whenever his/her need during walking. The rest time will be measured and documented.
Study: NCT04839055

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Coenzyme A Combined With Abiraterone
Description: Abiraterone 4 pieces per day. Coenzyme A 200U

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Abiraterone
Description: Abiraterone
Study: NCT04786418

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Participants allocated to the control group will be given standard clinical information regarding healthy eating, physical activity and management of weight, in line with current NHS practise.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low-calorie diet
Description: The LCD intervention group, will received a well validated, commercially available, intensive weight management protocol Counterweight-Plus.
Study: NCT05549349

Intervention type: PROCEDURE
Intervention: Cholecystectomy
Description: Gallbladder removal

Intervention type: PROCEDURE
Intervention: Cholecystectomy
Description: Gallbladder removal
Study: NCT05401383

Intervention type: DEVICE
Intervention: Lumevis (IIa class)
Description: intake of Lumevis 30 minutes before EGDS
Study: NCT05597423

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: The massage will be applied for 16 minutes on the quadriceps, calf, hamstrings and lower back bilaterally with 4 different pressures.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The cream will be applied to the quadriceps, calf, hamstring and lower back bilaterally and the participant will wait 16 minutes lying down in the supine position.
Study: NCT05578430

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: 10mg/kg by intravenous infusions every 3 weeks

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TACE
Description: TACE will be performed per institutional standard of care.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Surgery will be performed per institutional standard of care.
Study: NCT05260099

Intervention type: DEVICE
Intervention: LPS Adsorber
Description: LPS Adsorber, binding endotoxin caused by suspected or verified gram-negative bacteria.
Study: NCT01298882

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diacerein

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study: NCT05418413

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CTB
Description: conventional Twin-block (CTB) will be comprised of maxillary and mandibular removable appliances having the labial bows, adam's clasps, and with no incisal capping.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ETB
Description: will be comprised of maxillary and mandibular removable 1.5-mm biocryl sheet will be adapted separately on maxillary and mandibular casts with help of vacuum machine, and Acrylic bite blocks with the inclined plane will be fabricated on biocryl sheets sim
Study: NCT05385237

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 4D-MRI
Description: Novel MR-imaging (MRI) and postprocessing techniques, making it possible to capture breathing-induced abdominal motion, including liver motion, under free-breathing. For the first time, these techniques - called 4D-MRI - were able to capture the abdominal organs with high spatial resolution in 3-dimensions at a high frame rate of 2-3 Hz and enabled an entirely new insight into the human body.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 4D-MRI
Description: Novel MR-imaging (MRI) and postprocessing techniques, making it possible to capture breathing-induced abdominal motion, including liver motion, under free-breathing. For the first time, these techniques - called 4D-MRI - were able to capture the abdominal organs with high spatial resolution in 3-dimensions at a high frame rate of 2-3 Hz and enabled an entirely new insight into the human body.
Study: NCT06510062

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sustained Acoustic Medicine
Description: The SAM device emits continuous ultrasound at 3 megahertz (MHz) frequency and 0.132 watts/cm2 intensity delivering 18,720 Joules of ultrasound per 4 hour treatment.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sustained Acoustic Medicine
Description: The SAM device emits continuous ultrasound at 3 megahertz (MHz) frequency and 0.132 watts/cm2 intensity delivering 18,720 Joules of ultrasound per 4 hour treatment.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sustained Acoustic Medicine
Description: The SAM device emits continuous ultrasound at 3 megahertz (MHz) frequency and 0.132 watts/cm2 intensity delivering 18,720 Joules of ultrasound per 4 hour treatment.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sustained Acoustic Medicine
Description: The SAM device emits continuous ultrasound at 3 megahertz (MHz) frequency and 0.132 watts/cm2 intensity delivering 18,720 Joules of ultrasound per 4 hour treatment.
Study: NCT05429593

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Tablet given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: Tablet given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide/dapagliflozin
Description: Tablet given orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide/dapagliflozin
Description: Tablet given orally
Study: NCT05784610

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Monitorage by TOF/PTC
Description: Installation of TOFscan® and monitoring by MAR appreciation on one of the patient's wrists and installation of TOFscan® and monitoring by ATP mode (MAR blind) on the other wrist Installation of TOFscan® and monitoring by ATP mode

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Monitorage by ATP
Description: Installation of TOFscan® and monitoring by ATP mode on one of the patient's wrists

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Monitorage by ATP
Description: Installation of TOFscan® and monitoring by ATP mode on one of the patient's wrists
Study: NCT05698732

Intervention type: DEVICE
Intervention: Coroflex® ISAR NEO coronary stent system
Description: Patients in whom treatment with Coroflex® ISAR NEO coronary stent system has been attempted

Intervention type: DEVICE
Intervention: Coroflex® ISAR NEO coronary stent system
Description: Patients in whom treatment with Coroflex® ISAR NEO coronary stent system has been attempted
Study: NCT05038553

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT04641117

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Walking and Power Training
Study: NCT05387512

Intervention type: DRUG
Intervention: Camrelizumab
Description: Patients with EGFR-mutation-negative and ALK-negative advanced non-squamous non-small cell lung cancer were treated with first-line chemotherapy in combination with camrelizumab.

Intervention type: DRUG
Intervention: Camrelizumab
Description: Patients with EGFR-mutation-negative and ALK-negative advanced non-squamous non-small cell lung cancer were treated with first-line chemotherapy in combination with camrelizumab.
Study: NCT05579132

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CN201
Description: The treatments include 2 cycles of induction treatment, 3 cycles of consolidation treatment, and up to 7 cycles of maintenance treatment. During the Treatment Period, subjects will receive CN201 by intravenous (IV) infusion once every week (QW), 4 weeks per treatment cycle. The subjects will receive 2 cycles of CN201 for induction. After induction treatment, the drug is discontinued for 2 weeks (treatment-free interval) before consolidation therapy is started, and each subsequent treatment cycle (4 weeks/treatment cycle) is followed by a 2-week treatment-free interval. Responders to induction treatment will continue to receive 3 cycles of consolidation treatment, followed by an additional up to 7 cycles of maintenance treatment, or until intolerable toxicity, disease progression, withdrawal of informed consent, loss to follow-up, receipt of other antitumor therapy, or death, whichever occurs first.
Study: NCT06232746

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnet System, DI Biofragmentable
Description: Anastomoses achieved by magnetic compression.
Study: NCT05578508

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stem Cells (MSCs)
Description: Endoscopic injection of allogeneic bone marrow derived mesenchymal stem cells (MSCs) to the ileal pouch.
Study: NCT05921097

Intervention type: DIAGNOSTIC_TEST
Intervention: Histamin-induced axon-reflex flare response
Description: Histamin-induced axon-reflex flare response

Intervention type: DIAGNOSTIC_TEST
Intervention: Local heating-induced axon-reflex flare response
Description: Local heating-induced axon-reflex flare response

Intervention type: DIAGNOSTIC_TEST
Intervention: 2-point discrimination tasks
Description: 2-point discrimination tasks

Intervention type: DIAGNOSTIC_TEST
Intervention: NC-Stat DPNCheck
Description: NC-Stat DPNCheck

Intervention type: DIAGNOSTIC_TEST
Intervention: QST
Description: QST

Intervention type: DIAGNOSTIC_TEST
Intervention: Biothesiometry
Description: Biothesiometry
Study: NCT06212089

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TR-012001
Description: A single dose of TR-012001 will be administered.

Intervention type: OTHER
Group type: OTHER
Intervention: Placebo
Description: A single dose of placebo will be administered.
Study: NCT06050447

Intervention type: PROCEDURE
Intervention: Right hemicolectomy
Description: Resection of the caecum and ascending colon is appropriate for patients with tumors located anywhere from caecum to the transverse colon

Intervention type: PROCEDURE
Intervention: Left hemicolectomy
Description: Resection of the sigmoid colon is appropriate for patients with tumors located anywhere from the distal transverse colon to the rectosigmoid junction.

Intervention type: PROCEDURE
Intervention: Sigmoid colon resection
Description: Resection of the sigmoid colon is appropriate for patients with tumors located in the sigmoid colon

Intervention type: PROCEDURE
Intervention: Anterior resection of the rectum
Description: AR is appropriate for tumors located in rectosigmoid junction and in the proximal rectum

Intervention type: PROCEDURE
Intervention: Low anterior resection of the rectum
Description: LAR is appropriate for tumors located in the middle and low rectum

Intervention type: PROCEDURE
Intervention: Abdominoperineal resection
Description: APR is appropriate for distal rectal cancers that invade the external sphincter or the levator muscles

Intervention type: PROCEDURE
Intervention: Total Colectomy
Description: Total abdominal colectomy may be indicated for patients with primary multiple cancer tumors
Study: NCT05167084

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metyrapone 250 mg Oral Tablets
Description: During one phase of the study: Metyrapone (pills of 250mg) on full stomach: Day 1 0-1-1, day 2 1-2-2, day 3 2-2-3 day 4 3-3-4 day 5 3-3-4 day 6 3-3-4 day 7 3-3-4 day 8 3-0-0

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 250 mg Tablets
Description: During another phase of the study: identical looking placebo pills starting Day 1 0-1-1, day 2 1-2-2, day 3 2-2-3 day 4 3-3-4 day 5 3-3-4 day 6 3-3-4 day 7 3-3-4 day 8 3-0-0

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrocortisone 19,9mg s.c., pulsatile with a flow rate of 10μl/s
Description: Hydrocortisone will be delivered subcutaneously via a pump in a pulsed fashion with a flow rate of 10μl/s from day 1 to day 8 in a total daily dose of 19.9mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (0,9% NaCl solution)
Description: Placebo (0,9% NaCl solution) 19.9 mg/d subcutaneously via a pump in a pulsed fashion with a flow rate of 10μl/s from day 1 to day 8
Study: NCT03543553

Intervention type: OTHER
Intervention: This is not an intervention study
Description: This is not an intervention study

Intervention type: OTHER
Intervention: This is not an intervention study
Description: This is not an intervention study
Study: NCT04896788

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Monitoring of the immune response
Description: Blood sample at 3,6,12,18 and 24 months in order to assess the blood level of anti-S1 / RBD anticoprs
Study: NCT05592184

Intervention type: OTHER
Intervention: Exercise
Description: The experimental protocol begins with the assessment of self-perceived pain intensity and perceived exertion when using different intensities of elastic resistance, during wrist flexion and extension, at a controlled speed of 1.5sec/ phase. To assess the intensity at which they will work, participants will perform 2 repetitions and will be allowed a rest of 60s between sets until they obtain a score of 3 on the Borg CR10 scale. Exercises should be performed with the subject's available ROM. Participants are asked to move their body and trunk as little as possible and to perform the exercise smoothly, without stopping or accelerating. The exercise will be performed in a seated position, with the back supported by the backrest and the forearm resting on a table, with the shoulders and elbows bent at 90o, leaving the wrist free, with the elastic bands held under the feet (stepping on them).

Intervention type: OTHER
Intervention: Exercise
Description: The experimental protocol begins with the assessment of self-perceived pain intensity and perceived exertion when using different intensities of elastic resistance, during wrist flexion and extension, at a controlled speed of 1.5sec/ phase. To assess the intensity at which they will work, participants will perform 2 repetitions and will be allowed a rest of 60s between sets until they obtain a score of 3 on the Borg CR10 scale. Exercises should be performed with the subject's available ROM. Participants are asked to move their body and trunk as little as possible and to perform the exercise smoothly, without stopping or accelerating. The exercise will be performed in a seated position, with the back supported by the backrest and the forearm resting on a table, with the shoulders and elbows bent at 90o, leaving the wrist free, with the elastic bands held under the feet (stepping on them).
Study: NCT06231537

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Visual oral examination
Description: Oral preventive examinations in the three groups will be conducted over a one-year period. Individuals with oral injuries will be referred to stomatology, aligning with the existing protocol. Histopathological examinations of the biopsied lesions will be performed at the Oral Pathology Laboratory of the Faculty of Dentistry at the Federal University of Rio de Janeiro, following the established procedures.~Users diagnosed with malignancy will be directed to receive treatment at the reference hospital, with monitoring carried out by the Basic Health Unit responsible for coordinating care, in accordance with the current protocol.~In addition to histopathological examinations, the Faculty of Dentistry will be available to conduct a physical examination and biopsy if the user is not attended to by the Municipal Health Department. This additional resource ensures comprehensive care for individuals who may not have immediate access to municipal health services.
Study: NCT05435560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: During the imaging scan subjects will receive an initial bolus of dexmedetomidine over 10 minutes. After the bolus has been administered, a constant infusion of dexmedetomidine will be maintained for the remainder of the scan (about 60 minutes).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: During the imaging scan subjects will receive an initial bolus of saline over 10 minutes. After the bolus has been administered, a constant infusion of saline will be maintained for the remainder of the scan (about 60 minutes).
Study: NCT05511337

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Caloric restriction and control oxalate and citrate foods
Description: Restriction of 500 kilocalories from the usual diet plus a decrease in oxalate-rich foods (\< 40 mg per day) and an increase in citrate-rich foods (\> 40 mEq per day) for 28 days. The treatment will be given through an individualized meal plan.

Intervention type: OTHER
Group type: OTHER
Intervention: Caloric restriction
Description: Restriction of 500 kilocalories from the usual diet for 28 days. The treatment will be given through an individualized meal plan

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-life intervention with control oxalate and citrate foods
Description: Decrease in oxalate-rich foods (\< 40 mg per day) and an increase in citrate-rich foods (\> 40 mEq per day) without restriction in kilocalories from the usual diet for 28 days. Treatment will be given only through dietary counseling.
Study: NCT05405699

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: digitalized group psychoeducation
Description: Problem Solving Approach based problem solving skills psychoeducation's session topics of eight weeks are as follows:~1. Introduction and warm-up,~2. Problem orientation-identifying the problem,~3. Identifying prior problems-Which do I want to start from?~4. Recognizing the losses caused by problems and complaints,~5. Setting reachable and realistic goals,~6. Generating alternatives -What can I do?~7. Regulating emotions,~8. Experimenting and exploring. The main outcomes of each session were determined, and sessions were completed in approximately one hour as a semi-structured interactive group training according to group dynamics.~Three days a week for eight weeks, informative posts were shared, asynchronous testing and self-discovery activities were carried out, and a synchronous tele-psychoeducation session was held once a week. Participants were connected to the live broadcast of the research team and interacted via text messages.
Study: NCT05479474

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet rich plasma
Description: Patients will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle.~* On the third month after the testicular PRP procedure, a TESE will be performed~* If the procedure is successful a new IVF cycle using the sperm procured from the procedure will be done.
Study: NCT05954572

Intervention type: DIAGNOSTIC_TEST
Intervention: standardized skin surface biopsy (SSSB)
Description: This technique is applied in four facial localizations, including the forehead, cheeks, and nose. The surface biopsy procedure is performed as follows: one cm² area was marked on a glass slide using a fine ruler. The designated skin area for sampling is gently swabbed with a dry gauze pad to create mild irritation. Subsequently, one drop of cyanoacrylate adhesive is applied to the marked area on the glass slide. The glass slide is carefully pressed onto the skin, allowing the adhesive to adhere. After approximately one minute, the glass slide is gently lifted. The sampled area on the glass slide is examined under x10 and x40 magnification. Immersion oil is applied to enhance visualization and determine the number of Demodex parasites within the marked area. An increased demodicosis is defined as the presence of five or more Demodex parasites per square centimeter of skin.

Intervention type: DIAGNOSTIC_TEST
Intervention: standardized skin surface biopsy (SSSB)
Description: This technique is applied in four facial localizations, including the forehead, cheeks, and nose. The surface biopsy procedure is performed as follows: one cm² area was marked on a glass slide using a fine ruler. The designated skin area for sampling is gently swabbed with a dry gauze pad to create mild irritation. Subsequently, one drop of cyanoacrylate adhesive is applied to the marked area on the glass slide. The glass slide is carefully pressed onto the skin, allowing the adhesive to adhere. After approximately one minute, the glass slide is gently lifted. The sampled area on the glass slide is examined under x10 and x40 magnification. Immersion oil is applied to enhance visualization and determine the number of Demodex parasites within the marked area. An increased demodicosis is defined as the presence of five or more Demodex parasites per square centimeter of skin.
Study: NCT05258591

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Axem Home
Description: Rehabilitation system comprised of functional near-infrared spectroscopy headband (measuring from the motor cortex), as well as tablet-based software application (guiding stroke survivors through rehabilitation exercises for their hands/arms).
Study: NCT05068947

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GV101
Description: GV101 administered once orally.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo