TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06332066

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin nasal spray
Description: Intranasal OT will be performed using a spray containing 24IU (12IU administered to each nostril), sorbitol, benzyl, alcohol glycerol, distilled water. Dosage and administration method was determined by standard OT studies instructions and guidelines. The substance will be prepared immediately after randomization by an external preparation and delivered and stored until administration under required conditions. The nasal spray will be self administered, with nursing staff supervising for proper administration of substance, and for supervision of side effects.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxytocin nasal spray
Description: Intranasal OT will be performed using a spray containing 24IU (12IU administered to each nostril), sorbitol, benzyl, alcohol glycerol, distilled water. Dosage and administration method was determined by standard OT studies instructions and guidelines. The substance will be prepared immediately after randomization by an external preparation and delivered and stored until administration under required conditions. The nasal spray will be self administered, with nursing staff supervising for proper administration of substance, and for supervision of side effects.
Study: NCT04755491

Intervention type: DEVICE
Intervention: Continuous veno-venous hemodiafiltration
Description: Treatment of KDIGO stage 3 AKI by CVVHDF, in which renal replacement therapy is applied using a combination of diffusion technique (dialysis) and convection technique (ultrafiltration). Indication, choice of CRRT modality, and CRRT settings are made by the clinician in charge, following international recommendations. The measurement of chloride transfer over 24h is performed during CVVHDF treatment.
Study: NCT06391047

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan's Squeeze Technique - manual therapy
Description: This technique was introduced by Brian R. Mulligan. In this technique the therapist places thumb along the tender joint margin and applies force centrally. The patient actively flexes knee and therapist progressively enhances force and at end applies overpressure. This force is decreased as knee moves towards extension. This method helps to maintain the meniscus in its normal position and corrects the derangement of meniscus.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physiotherapy
Description: It includes stretching and strengthening exercises of muscles of the knee joint.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physiotherapy
Description: It includes stretching and strengthening exercises of muscles of the knee joint.
Study: NCT05081895

Intervention type: DEVICE
Intervention: Electrical Impedance tomography
Description: Patients will be monitored with electrical impedance tomography during routine care with special attention to effects of neuromuscular blockade and postural changes.

Intervention type: OTHER
Intervention: Lung mechanics and gas exchange
Description: Patient lung mechanics and gas exchange will be monitored during routine clinical care, with specific attention to postural changes and use of neuromuscular blockade.
Study: NCT05976802

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose budesonide rectal foam
Description: Twice a day for 2 weeks, then once a day for 4 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low dose budesonide rectal foam
Description: Twice a day for 2 weeks, then once a day for 4 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching placebo rectal foam
Description: Twice a day for 2 weeks, then once a day for 4 weeks
Study: NCT04915729

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tenecteplase
Description: tenecteplase

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: alteplase
Description: alteplase
Study: NCT06030414

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LMN-301
Description: Intranasally administered powder.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LMN-301
Description: Intranasally administered powder.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LMN-301
Description: Intranasally administered powder.
Study: NCT05672277

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TENS 1
Description: Parasacral TENS will be applied for 30 minutes 3 days a week during 6 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TENS 2
Description: Parasacral TENS will be applied for 30 minutes one day a week during 6 weeks.
Study: NCT06465160

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MNV-201 (Autologous CD34+ Cells Enriched with allogenic Placenta Derived Mitochondria)
Description: The participant will undergo 5 days of mobilization by G-CSF administration (Neupogen) once a day during 5 days.~On the 5th day, and after receiving the last dose of Neupogen, the participant will undergo Apheresis to collect CD34+ cells.~MNV-201 consists of autologous CD34+ cells enriched with allogeneic placenta derived mitochondria. Autologous CD34+ cells are isolated from the participant's peripheral blood after mobilization by apheresis. Allogeneic mitochondria are isolated under aseptic conditions from healthy donor placenta, cryopreserved and qualified before use.~Each product package will consist of a ready-for-injection sterile infusion bag containing clinical grade MNV-201 product for IV infusion for a single specified (autologous) participant.
Study: NCT06030414

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LMN-301
Description: Intranasally administered powder.
Study: NCT06006195

Intervention type: OTHER
Intervention: patients with dysphagia symptoms
Description: patients with dysphagia symptoms examined by high resolution impedance manometry

Intervention type: OTHER
Intervention: patients without dysphagia symptoms
Description: patients without dysphagia symptoms examined by high resolution impedance manometry
Study: NCT05708495

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: posterior ilium mobilization
Description: the therapist will mobilize the innominate on the affected side posteriorly

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: strengthening and stretching exercises
Description: the participants will receive strengthening exercises on the hip and knee joint beside that they will receive stretching exercises

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strengthening and stretching exercises
Description: the participants will receive strengthening exercises on the hip and knee joint beside that they will receive stretching exercises
Study: NCT04846010

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: PurWet
Description: (1) cang zhu (Atractylodis Rhizoma), bai (zhu Atractylodis macrocephalae Rhizoma), dang shen (Codonopsis Radix), huang qi (Astragali Radix), Fu ling (Poria), Zhu ling (polyporus), Ze xie (Alismatis Rhizoma), Yi yi ren (Coicis Semen), gan cao (Glycyrrhizae Radix),

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: FurFat
Description: (2).shan zha (Crataegi Fructus), Jue Ming Zi (Cassiae Semen), He ye (Nelumbinis Folium), Da huang (Rhei Radix et Rhizoma), Ze xie (Alismatis Rhizoma), dan shen ( Salviae miltiorrhizae Radix).
Study: NCT05800054

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutritional Support Team
Description: Nutritionists formulate nutritional programs and manage them in a refined manner. On the basis of the patient's natural diet (food and homogenate meal), enteral nutritional preparations or parenteral nutritional supplements are given according to the patient's gastrointestinal obstruction, dietary structure, and food intake. Energy 30-35kcal/kg/d, protein 1.2-1.5g/kg/d. Enteral nutrition administration route: oral or tube feeding or ostomy, oral feeding is preferred; severe obstruction of eating or oral intake cannot meet the target nutrition, choose tube feeding or ostomy. When it is expected that enteral nutrition cannot meet 60% of the target energy requirement for 3 to 5 days, choose parenteral nutrition. The enteral nutritional preparation adopts the whole protein enteral nutritional preparation Nengquan, and/or the tumor nutritional preparation Ruineng, and/or whey protein powder.
Study: NCT04846010

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: PurApo
Description: (3)Sheng Di Huang (Rehmanniae Radix), Xuan Shen (Scrophulariae Radix), mai men dong (Ophiopogonis Radix), shan zhu yu (Corni Fructus), shan yao (Dioscoreae Rhizoma), sha yuan zi (Astragali complanati Semen), ci ji li (Tribuli Fructus), nu zhen zi (Ligustri lucidi Fructus)

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: PurPhl
Description: (4) chen pi (Citri reticulatae Pericarpium), hua ju hong (Citri grandis Exocartium rubrum), zhi shi (Aurantii Fructus immaturu), zhi ban xia (Pinelliae Rhizoma preparatum), zhi tian nan xing (Arisaematis Rhizoma preparatum),sha ren (Amoni Fructus), Gua lou (Trichosanthis Fructus), Chuan bei mu ( Fritillatiae cirrhosae Bulbu), Fu ling ( Poria), Da huang ( Rhei Radix et Rhizoma).

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: PurClo
Description: (2) Dan shen (Salviae miltiorrhizae Radix), Yu jin (Curcumae Radix), chi shao (Paeoniae Radix rubra), tao ren (Persicae Semen), hong hua (Carthami Flos)
Study: NCT05800054

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: 60-75 mg/m2, d1, at least 2 cycles in parallel with radiotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: 60-75 mg/m2, d1, at least 2 cycles in parallel with radiotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cisplatin
Description: cisplatin 25mg/m2 d1-3, 21-28d/cycle. at least 2 cycles in parallel with radiotherapy
Study: NCT04846010

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: PurInf
Description: (1) lei gong teng (Tripterygii wilfordii Radix), Huang Qin (Scutellariae Radix), Huang Lian (Coptidis Rhizoma), Huang Bai (Phellodendri Cortex), Zhi Zi (Gardeniae Fructus).

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Smoliv
Description: (2). Vagus never communicates with LES: yu jin (Curcumae Radix), Chai Hu (Bupleuri Radix), chi shao (Paeoniae Radix rubra), Mu Dan Pi (Moutan Cortex), chuan lian zi (Toosendan Fructus), long gu (Fossilia Ossis Mastodi), mu li (Ostreae Concha)
Study: NCT05392920

Intervention type: OTHER
Intervention: assessment study
Description: there is no intervention in this study
Study: NCT04952610

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etripamil NS 70 mg
Description: Etripamil will be administered via the Aptar Pharma Nasal Spray Bidose System.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aptar Pharma Nasal Spray Bidose System
Description: Aptar Pharma Nasal Spray Bidose System will be supplied as prefilled devices packaged into child-resistant boxes with instructions for use provided in the study drug box.
Study: NCT05726409

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile application
Description: Participants will use the meal planner function on the mobile application to plan and cook at least 3 meals a week for 12 weeks.
Study: NCT06405048

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile Weibo post screenshot with mock-up Chinese fact-checking extension
Description: The intervention in this survey experiment involves mobile Weibo post screenshots equipped with a mock-up Chinese fact-checking browser extension. All screenshots are based on actual Weibo posts. The fact-checking content is generated by a Large Language Model (LLM), tailored to relevant knowledge and prompts, and subsequently validated by experts. The Weibo posts cover a range of popular topics known to contain misinformation, including infertility, safety, vaccine ingredients, high-risk cervical cancer types, regular check-ups, transmission routes, and others.
Study: NCT05800054

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cisplatin
Description: cisplatin 25mg/m2 d1-3, 21-28d/cycle. at least 2 cycles in parallel with radiotherapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: image-guided intensity-modulated radiotherapy (IGRT) or intensity-modulated radiotherapy (IMRT); Irradiation targets include primary lesions, clinical targets, positive lymph nodes, and lymph node drainage areas. Dose splitting/prescription dose, 95% volume PGTV-T60-66Gy/30-35 times, PGTV-N 60-66Gy/30-35 times, PCTV-T 46-50Gy/23-25 times, PCTV-N46-50Gy/23-25 times.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: image-guided intensity-modulated radiotherapy (IGRT) or intensity-modulated radiotherapy (IMRT); Irradiation targets include primary lesions, clinical targets, positive lymph nodes, and lymph node drainage areas. Dose splitting/prescription dose, 95% volume PGTV-T60-66Gy/30-35 times, PGTV-N 60-66Gy/30-35 times, PCTV-T 46-50Gy/23-25 times, PCTV-N46-50Gy/23-25 times.
Study: NCT06243133

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: clopidogrel for 90 days combined with aspirin for 90 days
Description: Clopidogrel 300mg on the first day, then 75mg/day for 90 consecutive days; Aspirin 100mg/day for 90 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: clopidogrel for 30 days combined with aspirin for 90 days
Description: Clopidogrel 300mg on the first day, then 75mg/ day for 30 consecutive days; Aspirin 100mg/ day for 90 days
Study: NCT06192602

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AIM_AT
Description: The program consists of 10 weekly/biweekly, 2-hour sessions (4-months), based on the modified Kemp's model/manual of Adherence therapy and mindfulness-based psychoeducation program developed by the research team.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CPG
Description: Psychoeducation group program (12-18 members/group) consists of 10 two-hour sessions, weekly/biweekly (similarly, 4-month duration) and is guided by a validated group-intervention protocol based on the research team's and McFarlane et al.'s psychoeducation programs for psychosis.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TAU
Description: Routine/Usual care only (control) group participants (and the two treatment groups) will receive usual community mental healthcare services.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: TAU
Description: Routine/Usual care only (control) group participants (and the two treatment groups) will receive usual community mental healthcare services.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: TAU
Description: Routine/Usual care only (control) group participants (and the two treatment groups) will receive usual community mental healthcare services.
Study: NCT06348511

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: XTics
Description: XTics is a gamified protocol of behavioral treatment for tic disorders. The participant's tics are monitored in real-time and they are reflected as achievements in a game that the participant plays at the same time. The rewards aim to counteract processes that consolidate the tic. XTics is compatible with ERP treatment, and it includes an introductory psychoeducation session and three behavioral training sessions.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: XTics
Description: XTics is a gamified protocol of behavioral treatment for tic disorders. The participant's tics are monitored in real-time and they are reflected as achievements in a game that the participant plays at the same time. The rewards aim to counteract processes that consolidate the tic. XTics is compatible with ERP treatment, and it includes an introductory psychoeducation session and three behavioral training sessions.
Study: NCT05958212

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gait training program
Description: Gait training program at PolyU is a supervised rehabilitation program performed on the dual-belt treadmill. It consists of forward walking at increased speed over the affected leg and retro walking (backward walking) at individual's own pace (5 minutes/set for three sets, with rest periods in each session). This program also consists of a standardized set of warm-up and cool-down exercises at each training session.~Participants will also receive conventional physiotherapy treatment in the outpatient physiotherapy clinic.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional training only
Description: Conventional physiotherapy treatment in the outpatient physiotherapy clinic.
Study: NCT04661865

Intervention type: OTHER
Group type: OTHER
Intervention: Health Information Package Program (HIP program )
Description: Fifteen minutes PowerPoint presentation will be introduced to women to increase women's educational experience and raise their level of engagement and commitment.~The principal investigator will narrate the video record with PowerPoint slides and it was recorded as a video and will include information regarding the introduction to pregnancy, causes and predisposing factors of iron deficiency anemia during pregnancy, signs and symptoms, prevention, management of iron deficiency anemia during pregnancy that includes iron therapy, iron supplementation, dietary management. Content validity for the information in the video will be done by sending it to three experts in maternity nursing. Iron supplementation will be given to all participants who will start by sixteen weeks of pregnancy and they will receive information regarding the proper usage of iron supplements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Information Package Program (HIP program )
Description: Fifteen minutes PowerPoint presentation will be introduced to women to increase women's educational experience and raise their level of engagement and commitment.~The principal investigator will narrate the video record with PowerPoint slides and it was recorded as a video and will include information regarding the introduction to pregnancy, causes and predisposing factors of iron deficiency anemia during pregnancy, signs and symptoms, prevention, management of iron deficiency anemia during pregnancy that includes iron therapy, iron supplementation, dietary management. Content validity for the information in the video will be done by sending it to three experts in maternity nursing. Iron supplementation will be given to all participants who will start by sixteen weeks of pregnancy and they will receive information regarding the proper usage of iron supplements.
Study: NCT05215509

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Supervised high-intensity interval training for 12 weeks three times per week. The supervision may be physical or online supervision

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Supervised high-intensity interval training for 12 weeks three times per week. The supervision may be physical or online supervision

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: No exercise
Description: Control group, therefore no supervised exercise regime
Study: NCT05456789

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: combined catheter-thrombectomy and local fibrinolysis
Description: combination of catheter-based thrombectomy with local pulmonary fibrinolysis plus conventional treatment
Study: NCT05215509

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: No exercise
Description: Control group, therefore no supervised exercise regime
Study: NCT05199649

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SintilimabCombined With Chemotherapy
Description: Sintilimab and chemotherapy are carried out at the same time for every 3 weeks
Study: NCT05769348

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HD-tDCS Active Protocol
Description: non-invasive brain stimulation (active protocol)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HD-tDCS Active Protocol
Description: non-invasive brain stimulation (active protocol)

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: HD-tDCS Sham Protocol
Description: non-invasive brain stimulation (sham protocol)
Study: NCT05456789

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional treatment
Description: conventional treatment of pulmonary embolism
Study: NCT05006261

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tele-Tai Chi
Description: 12-week simplified TC program using the Tele-TC platform at home, with recommended training sessions at least three times a week, and two or more supplementary live sessions.
Study: NCT06360159

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention
Description: As an intervention, the newborn will be massaged.
Study: NCT06008015

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR1015
Description: One tablet administered alone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BR1015-1
Description: One tablet administered alone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BR1015-2
Description: One tablet administered alone
Study: NCT06082427

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality hypnosis
Description: VRH was delivered through a 3D virtual reality headpiece equipped with a head-tracking system based on hypnosis induction and suggestions (relaxation, comfort, and safety). The complete intervention lasted 17 minutes.
Study: NCT06041100

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Exoskeleton
Description: Use a passive assistive hip exoskeleton (alQ, Imasen Electrical Industrial Co., Ltd.) for 30 minutes daily during moderate to intensive activities over a period of 12-weeks. The exoskeleton is designed to aid hip flexion and as such its primary role is to improve gait by increasing step length and improving speed. The amount of time the exoskeleton has been used will be weekly monitored through phone calls and two gait sessions will be conducted to measure the development.
Study: NCT06129500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy for Problematic Impulsive Behaviours
Description: Up to 12 sessions of Cognitive Behavioural Therapy adapted to focus on mood-driven impulsivity in adults with bipolar disorder.
Study: NCT05247606

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile application
Description: Lifestyle intervention through web-based mobile application
Study: NCT06250972

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gemcitabine, Nab-paclitaxel, Irinotecan
Description: continuing chemotherapy using the previous regimen until disease progression

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity-Modulated Radiation Therapy (IMRT)
Description: Receive Intensity-Modulated Radiation Therapy (IMRT) after about 2\~6 cycles of chemotherapy.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Intensity-Modulated Radiation Therapy (IMRT)
Description: Receive Intensity-Modulated Radiation Therapy (IMRT) after about 2\~6 cycles of chemotherapy.