TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05131165

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Daily Text Messages
Description: Participants will receive daily text message reminders to use their routine behavior to trigger medication adherence.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Daily Text Messages
Description: Participants will receive daily text message reminders to use their routine behavior to trigger medication adherence.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Incentivization based on timely ART adherence
Description: Participants will be eligible to draw a prize if they take their medication within +/- one hour of the stated existing routine to which pill-taking is anchored on at least 70% of days between recruitment and the 3-month study visit.
Study: NCT05317403

Intervention type: DRUG
Group type: OTHER
Intervention: Venetoclax
Description: Dose Level 0: Day 1 60 mg/m2 PO x1, Days 2-14 120 mg/m2/dose PO once daily (Max: 200 mg/day)~Dose level 1: Day 1 120 mg/m2 PO x1, Days 2-14 240 mg/m2/dose PO once daily (Max: 400 mg/day)~Dose level 2: Day 1 180 mg/m2 PO x1, Days 2-14 360 mg/m2/dose PO once daily (Max: 600 mg/day)

Intervention type: DRUG
Group type: OTHER
Intervention: Venetoclax
Description: Dose Level 0: Day 1 60 mg/m2 PO x1, Days 2-14 120 mg/m2/dose PO once daily (Max: 200 mg/day)~Dose level 1: Day 1 120 mg/m2 PO x1, Days 2-14 240 mg/m2/dose PO once daily (Max: 400 mg/day)~Dose level 2: Day 1 180 mg/m2 PO x1, Days 2-14 360 mg/m2/dose PO once daily (Max: 600 mg/day)

Intervention type: DRUG
Group type: OTHER
Intervention: Azacitadine
Description: 75 mg/m2/dose IV once daily over 15 minutes

Intervention type: DRUG
Group type: OTHER
Intervention: Azacitadine
Description: 75 mg/m2/dose IV once daily over 15 minutes

Intervention type: DRUG
Group type: OTHER
Intervention: Vorinostat
Description: 1 year to 17.99 years old: 180 mg/m2/dose PO once daily~≥18 years old 200 mg PO BID. Doses should be separated by 12 hr (±4 hr)

Intervention type: DRUG
Group type: OTHER
Intervention: Vorinostat
Description: 1 year to 17.99 years old: 180 mg/m2/dose PO once daily~≥18 years old 200 mg PO BID. Doses should be separated by 12 hr (±4 hr)

Intervention type: DRUG
Group type: OTHER
Intervention: Cytarabine
Description: 2000 mg/m2/dose IV once daily over 3 hours~IT Cytarabine:~1. - 1.99 years old: 30 mg~2. - 2.99 years old: 50 mg~   * 3 years old: 70 mg

Intervention type: DRUG
Group type: OTHER
Intervention: Cytarabine
Description: 2000 mg/m2/dose IV once daily over 3 hours~IT Cytarabine:~1. - 1.99 years old: 30 mg~2. - 2.99 years old: 50 mg~   * 3 years old: 70 mg

Intervention type: DRUG
Group type: OTHER
Intervention: Fludarabine
Description: 30 mg/m2/dose IV once daily over 30 minutes

Intervention type: DRUG
Group type: OTHER
Intervention: Fludarabine
Description: 30 mg/m2/dose IV once daily over 30 minutes

Intervention type: DRUG
Group type: OTHER
Intervention: Filgrastim
Description: 5 microgram/kg/dose subcutaneous (or IV over 15-30 min) once daily

Intervention type: DRUG
Group type: OTHER
Intervention: Filgrastim
Description: 5 microgram/kg/dose subcutaneous (or IV over 15-30 min) once daily
Study: NCT04072783

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: MRI,DTI, functional MRI
Description: 1. Patients will undergo testing with Pre- and and post-surgical MRI. The protocol will be Sagittal T1, Axial inversion recovery, T2, fluid-attenuated inversion recovery, susceptibility weighted image, diffusion weighted images, diffusion tensor imaging, resting state fMRI, sagittal 3D GRE / FFE or 3D T1 VIBE and tractography.~2. Once patients are identified, surgery is planned.The standard of care procedures fall into two categories based on age of presentation, clinician judgement and family preference all other things being equal. Both the endoscopic-assisted craniectomy and open CVR are standard of care procedures. Patients self-select into these groups. None of the surgery nor any aspect of it is experimental.~3. Patients are routinely examined for neurodevelopment pre- and post-operatively as part of American Cleft Palate Craniofacial Association guidelines.The Vineland Adaptive Behavior Scales are used up to and including age 4.
Study: NCT06517160

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MedBook Portal
Description: Intervention Group (With MedBook Portal \&amp; MedBook Portal Notice)~1. MedBook Portal Notice in front of the patient home-based medical card~2. Discharge prescriptions are uploaded into MedBook Portal and can be retrieved by doctors \&amp; pharmacists.~MedBook portal (https://aplikasi.jknsarawak.moh.gov.my/medbook) is a webpage that enable sharing of patient medication records among healthcare facilities under Ministry of Health. Sarawak State Health Department owned and managed this portal. All the information is kept under their server. Doctors in the Health Clinics and Study Pharmacists will be given access to this portal whereby each of the healthcare providers shall log in using their Identification Number and the password created by them. Doctor shall log in to MedBook Portal to check on discharge medication list when reviewing the patient at health clinic. MedBook Portal can be accessed both using a smartphone or a computer.
Study: NCT05127044

Intervention type: DEVICE
Group type: OTHER
Intervention: Diffuse Reflectance Spectroscopy
Description: DRS will be used as a non-invasive optical spectroscopy method to collect key biological information from neonatal skin including skin maturity, blood oxygenation, and bilirubin content.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: BiliChek
Description: BiliChek will be used as a control for determining bilirubin content.
Study: NCT05823948

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Icodec
Description: Participants will receive insulin icodec once-weekly subcutaneously into the thigh, upper arm or abdomen.
Study: NCT04866810

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention Arm
Description: High fiber, plant based diet + exercise prescription with ACT sessions

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control
Description: Standard diet and exercise recommendations
Study: NCT06244433

Intervention type: GENETIC
Intervention: whole genome sequencing
Description: Study of all coding and non-coding sequences in the genome to identify pathogenic allelic variants

Intervention type: GENETIC
Intervention: whole genome sequencing
Description: Study of all coding and non-coding sequences in the genome to identify pathogenic allelic variants
Study: NCT05498883

Intervention type: OTHER
Group type: OTHER
Intervention: Score completion
Description: completion of the SRI score
Study: NCT06587113

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual tasks
Description: In the experiments, participants sit in front of a computer screen with their head in a chinrest to control for distance from the monitor and eye-tracking equipment. For the visual search task, participants will search for a visual target among distractors and make a response regarding its orientation. For the stop-signal task, participants will make an eye movement to a target that appears on the screen, except on trials where a visual signal appears indicating they should cancel this behavior. In the useful field of view task, participants will report the location of a briefly-presented and masked target, while also responding to the identify of a central target in some blocks.
Study: NCT06601608

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Herbal therapy
Description: rosemary extract gel is used for the first time as a local drug delivery as an adjunct to non-surgical periodontal therapy in management of stage III periodontitis patients.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Drug
Description: a placebo gel will be applied in deep pockets (\&gt;5mm) in stage III periodontitis patients as an adjunct to non-surgical periodontal therapy
Study: NCT06590636

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Expressive touching
Description: Woman's anxiety level was measured with the State-Trait Anxiety Inventory scale Following these measurements, expressive touching that lasted 15-20 minutes was performed in the following manner.~The hands of the expressive touching performer warmed to body temperature (should not be cold).~The woman's hand close to the performer was placed between the hands of the expressive touching performer.~The woman's palm was gently grasped with the palms of the expressive touching performer.~The hand below was fixed and the upper part of the woman's hand was gently rubbed with the hand above.~Before and after massaging, the woman's arms and shoulders were touched at intervals.~During the procedure, the woman was called by her name, and verbal communication with the woman was continued by holding her hands firmly and sincerely as if a handshaking done.~Before the woman's discharge from the center, her anxiety level was measured with the State-Trait Anxiety Inventory scale
Study: NCT06586060

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: lung ultrasound guided fluid balance strategy
Description: Lung ultrasound (LUS) guided fluid management based on B-Line score assessment using LUS within 24 hours of icu admission and daily thereafter until icu discharge or for up to 14 days after randomization which ever comes first~In patients with BLS = 0-14, a zero fluid balance (FB) will be targeted if no signs of shock are present. In patients with BLS ≥ 15, a daily negative FB of -250 to -1000 mL will be targeted until BLS drops under 15. To reach daily targeted FB, furosemide-induced diuresis and RRT will be used In case of shocked patients with BLS \&amp;amp;lt; 15: they will receive fluid boluses and packed RBCs to achieve a Hb of 10 and a MAP of \&amp;amp;gt;65 mmHg.~In case of shocked patients with BLS ≥ 15: they will start norepinephrine infusion to reach a MAP of \&amp;amp;gt;65 mmHg.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: usual care guided fluid balance strategy
Description: fluid balance management will be guided to maintain an adequate intravascular volume while minimising weight gain within 24 hours of icu admission and daily thereafter until icu discharge or for up to 14 days after randomization which ever comes first. Various parameters will be used to attain this goal based on case-by-case clinical judgment: lung sounds, heart rate, blood pressure, temperature, urine output, lactate, haemoglobin, haematocrit, serum urea, creatinine, sodium, potassium, chloride, and bicarbonate values To reach daily targeted fluid balance, furosemide-induced diuresis and RRT will be used
Study: NCT06587009

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Shock wave therapy
Description: Received shock wave therapy 7 times a week and functional exercise therapy intervention

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional conservative treatment
Description: Conventional conservative treatment and functional exercise were given
Study: NCT06602076

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ECHO (Empowering Our Community & Health Outcomes)
Description: Additive intervention design wherein study participants receive remotely-delivered standard smoking cessation support (i.e., behavioral support plus nicotine replacement therapy) and engage in sexual and/or gender minoritized (SGM)-serving volunteer activities.
Study: NCT06601257

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin (IV)
Description: Vancomycin weight-based or kidney function-based dosing

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin (IV)
Description: Vancomycin weight-based or kidney function-based dosing
Study: NCT06598826

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Graston technique (IASTM)
Description: Group A includes 26 patients post ND who received Graston technique (IASTM) , in additional to traditional treatment (ROM exercise, strengthening exercise, and stretching exercise) for 1 month

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio taping
Description: Group B includes 26 patients who received Kinesiotaping, in addition to traditional treatment (ROM exercise, strengthening exercise, and stretching exercises) for 1 month
Study: NCT06603467

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: non-guided de-epithelialized free gingival graft harvested
Description: gingival recession will be covered with de-epithelialized free gingival graft harvested without guide

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: guided de-epithelialized free gingival graft harvested
Description: gingival recession will be covered with de-epithelialized free gingival graft harvested with digital guide
Study: NCT06604221

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance exercise intervention
Description: The exercise prescription, developed through expert meetings and integrated review summaries, consists of 27 items including: participant preparation, team preparation, exercise prescription FITT-VP, process monitoring, discontinuation criteria, termination criteria, recovery methods, outcome measures, and special considerations.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine care
Description: 1.Pre-dialysis Assessment:~1. Vital Signs: Monitor blood pressure, heart rate, temperature.~2. Access Care: Check the vascular access site for signs of infection and patency. 2.During Dialysis:~（1）Monitoring: Continuous vital signs and machine settings monitoring. （2）Fluid Management: Control fluid removal based on pre-dialysis weight. 3.Post-dialysis Care:~1. Observation: Monitor for complications like hypotension, cramps, or bleeding.~2. Weight Check: Weigh post-dialysis to verify fluid removal. 4.Education and Support:~（1）Diet: Educate on dietary restrictions (potassium, phosphorus, fluids). （2）Medications: Advise on medication adjustments. 5.Psychosocial Support:~（1）Provide emotional support and counseling.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine care
Description: 1.Pre-dialysis Assessment:~1. Vital Signs: Monitor blood pressure, heart rate, temperature.~2. Access Care: Check the vascular access site for signs of infection and patency. 2.During Dialysis:~（1）Monitoring: Continuous vital signs and machine settings monitoring. （2）Fluid Management: Control fluid removal based on pre-dialysis weight. 3.Post-dialysis Care:~1. Observation: Monitor for complications like hypotension, cramps, or bleeding.~2. Weight Check: Weigh post-dialysis to verify fluid removal. 4.Education and Support:~（1）Diet: Educate on dietary restrictions (potassium, phosphorus, fluids). （2）Medications: Advise on medication adjustments. 5.Psychosocial Support:~（1）Provide emotional support and counseling.
Study: NCT06594393

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCP-25 gel
Description: Topical gel

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle (placebo)
Description: Placebo gel
Study: NCT06670001

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gamification plus social incentive
Description: Participants in the Gamification plus social incentive intervention arm will receive gamification and social incentives as part of the intervention. See arm descriptions for more detail.
Study: NCT05319782

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Urethral stenosis assesment
Description: Auto-questionnaires + Clinical examination + Flow metry and post-mictional residue
Study: NCT06670001

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gamification plus competition
Description: Participants in the Gamification plus competition intervention arm will receive gamification and a competition as part of the intervention. See arm descriptions for more detail.
Study: NCT06615076

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Postpartum Visits
Description: Postpartum visits with obstetric care providers

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Postpartum Visits
Description: Postpartum visits with study RN.
Study: NCT06520787

Intervention type: COMBINATION_PRODUCT
Intervention: ACDP® and pharmacological treatment for obesity
Description: 40 Families of children with obesity that are already undergoing treatment and are willing to join a combined intervention. After the recruitment, the family will join Adhera Caring Digital Program® for 10 months. The combined intervention (digital and pharmacological intervention) will last one year, and there will be a 2-month follow-up. During the whole study (12 months, from recruiting to the end of follow-up) participants will wear a smartwatch (Fitbit or similar).
Study: NCT06591169

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: diet restriction and exercise
Description: this group will contain twenty obese females with a complaint of NAFLD, PCOS and OSA. for eight weeks, these obese females will receive metformin tablet (thrice daily), program of low diet intake, and daily walking for 30 minutes

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: diet restriction
Description: this group will contain twenty obese females with a complaint of NAFLD, PCOS and OSA. for eight weeks, these obese females will receive metformin tablet (thrice daily) and program of low diet intake
Study: NCT06593132

Intervention type: PROCEDURE
Intervention: endoscopic breast conserving surgery
Description: Breast endoscopy technology completes complex surgical operations through small incisions, achieving aesthetically pleasing results while ensuring tumor safety.

Intervention type: PROCEDURE
Intervention: endoscopic breast conserving surgery
Description: Breast endoscopy technology completes complex surgical operations through small incisions, achieving aesthetically pleasing results while ensuring tumor safety.
Study: NCT05943834

Intervention type: OTHER
Intervention: Series of cognitive tasks during a semi-automated call
Description: Tasks:~* Verbal learning recall (immediate) or Story Recall task (immediate)~* Narrative Storytelling /free speech~* Verbal fluency task~* Verbal learning recall (delayed) or Story Recall task (delayed)
Study: NCT06630598

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online Family Violence Education Resource
Description: The VEGA Family Violence Education Resources (© 2020 VEGA Project, McMaster University) is an on-line suite of educational resources that target professionals who are likely to encounter survivors of family violence in professional and clinical settings. The resources provide information about family violence, appropriate clinical responses, legal obligations, and more. The resources are broken down into several training modules and include three interactive learning scenarios. The training modules include:~Know About Family Violence in Canada Creating Safety Recognizing and Responding Safely to Child Maltreatment Recognizing and Responding Safely to Intimate Partner Violence Voices of those with Lived Experiences of Family Violence
Study: NCT06632639

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Corrective exercise protocol
Description: The program requires 60 minutes consisting of a ten-minute warm-up, a forty-minute Thera-band exercise, and a ten-minute cool-down. Thera-band exercises are to improve the external rotators, and the extensors and for strengthening the quadriceps and the gluteus. A set consists of 15 reps, each of the exercise methods consisted of three sets.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Corrective exercise protocol
Description: The program requires 60 minutes consisting of a ten-minute warm-up, a forty-minute Thera-band exercise, and a ten-minute cool-down. Thera-band exercises are to improve the external rotators, and the extensors and for strengthening the quadriceps and the gluteus. A set consists of 15 reps, each of the exercise methods consisted of three sets.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lateral wedged insoles with subtalar strapping
Description: A silicon rubber 10 mm lateral wedge has a 10 mm lateral elevation and a 75 mm width, which has an approximately 7.6 inclination. This silicon rubber material is usually used for cosmetic remodeling and has a natural form-fit to the skin. The 75 mm width silicon rubber is scaphoid shaped and it is suitable for attachment to a barefoot of all of the subjects. The rational for using this inclination is that 7.6 is approximately the median between 5 and 10. Patients will be instructed to use the wedge in an appropriate shoe (not high heels or narrow-toed shoes), 1 h a day during the first week. The duration of use gradually will be increased to the minimum of 8 h a day.
Study: NCT06699927

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Span
Description: The training program is a personal device-based adaptive version of a visual working memory span task, either devoid of game elements or embedded in a gamified platform game

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Span
Description: The training program is a personal device-based adaptive version of a visual working memory span task, either devoid of game elements or embedded in a gamified platform game
Study: NCT06702410

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mental health gap action program intervention guide (mhGAP-IG)
Description: The mhGAP-IG is an evidence-based intervention developed by WHO. It was designed for non-specialists to scale up high quality mental health services. Although more than 90 countries worldwide have implemented mhGAP-IG, this study is the first to evaluated if it works for scaling up CMBDs services in China. Investigators have cultrually adapted the mhGAP-IG according Chinese context.
Study: NCT06705257

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Studying the effects of varying levels of PEEP using Electrical impedance tomography
Description: Feasibility of using EIT, to study the effect of varying levels of PEEP/Continous distending pressure on lung recruitment as measured by changes in functional lung scores and silent spaces in preterm infants (\<32 weeks) who are on mechanical ventilation or receiving primary or post extubation CPAP support.
Study: NCT06702644

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Remote ischemic conditioning
Description: Remote ischemic conditioning: Remote ischemic conditioning (RIC) is induced by 5 cycles of 5 min of bilateral upper limbs ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 200 mmHg.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham remote ischemic conditioning
Description: Sham remote ischemic conditioning (RIC) is induced by 5 cycles of 5 min of bilateral upper limbs ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 60 mmHg.