TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06208839

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SBIRT/eIntervention for those with moderate risk drug or alcohol use
Description: The Connections App is available on iOS or Android and will be offered to the patient during the referral process and contains the following functionalities:~* Online view of the referrals made for them e.g. to healthcare provider~* Secure messaging with the referring provider~* Secure messaging with the destination provider(s) to support them to adhere to the referral, and/or the patient can seek assistance with the destination provider,~* Informative multimedia content filtered from a library to fit the patient including testimonial content from peers thus showing the patient that others like them have shared their addiction experience and successfully received treatment and achieved recovery,~* Capture structured feedback from the patient~The patient may access more functionality within the Connections App for those who wish to modify behavior using eTherapy and eRecovery. eRecovery includes ecological momentary assessments (EMA) selected by the provider.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SBIRT/eIntervention those assessed with high risk.
Description: The Connections App is available on iOS or Android and will be offered to the patient during the referral process and contains the following functionalities:~* Online view of the referrals made for them e.g. to healthcare provider~* Secure messaging with the referring provider~* Secure messaging with the destination provider(s) to support them to adhere to the referral, and/or the patient can seek assistance with the destination provider,~* Informative multimedia content filtered from a library to fit the patient including testimonial content from peers thus showing the patient that others like them have shared their addiction experience and successfully received treatment and achieved recovery,~* Capture structured feedback from the patient~The patient may access more functionality within the Connections App for those who wish to modify behavior using eTherapy and eRecovery. eRecovery includes ecological momentary assessments (EMA) selected by the provider.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SBIRT/TAU for those with moderate risk drug or alcohol use
Description: Treatment as usual
Study: NCT05454852

Intervention type: OTHER
Intervention: Survey
Description: Interviewer-administered survey
Study: NCT06208839

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SBIRT/TAU for those assessed with high risk.
Description: Treatment as usual for high risk group
Study: NCT05454852

Intervention type: OTHER
Intervention: Focus group
Description: Focus group for selected participants
Study: NCT06445491

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control order
Description: Participants will perform an initial baseline of tests, order of 1- 2- 3

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Randomized sequence
Description: the testing order will be randomized for follow up testing.
Study: NCT06622512

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radial Pressure Wave Therapy
Description: Radial pressure wave therapy (RPWT) is a non-invasive treatment used for musculoskeletal disorders, including knee OA. (Schroeder AN) It involves the application of mechanical energy to stimulate biological responses, RPWT differs fundamentally from focal shock wave therapy (FSWT) in several physical properties, in its point of maximum energy flux density (EFD), and in some clinical applications. RPWT activates cellular pathways involved in tissue regeneration and generates mechanical energy that spreads radially from the point of application, primarily affecting superficial tissues and leading to pain relief and improved function through a process known as mechano-transduction, by enhancing blood flow and stimulating cellular repair processes . (Simplicio CL, Wang CJ)
Study: NCT04947384

Intervention type: DIAGNOSTIC_TEST
Intervention: To discern micro-RNA specific for right and left heart induced PH
Description: While undergoing other procedures, the investigators will be collecting a total of three blood samples. The first sample will be obtained on arterial cannulation before the initiation of the intervention, the second sample will be collected upon the end of the procedure prior to leaving the procedure room, and the third sample will be collected on the day of discharge from the hospital.

Intervention type: DIAGNOSTIC_TEST
Intervention: To discern micro-RNA specific for right and left heart induced PH
Description: While undergoing other procedures, the investigators will be collecting a total of three blood samples. The first sample will be obtained on arterial cannulation before the initiation of the intervention, the second sample will be collected upon the end of the procedure prior to leaving the procedure room, and the third sample will be collected on the day of discharge from the hospital.

Intervention type: DIAGNOSTIC_TEST
Intervention: To discern micro-RNA specific for right and left heart induced PH
Description: While undergoing other procedures, the investigators will be collecting a total of three blood samples. The first sample will be obtained on arterial cannulation before the initiation of the intervention, the second sample will be collected upon the end of the procedure prior to leaving the procedure room, and the third sample will be collected on the day of discharge from the hospital.
Study: NCT05379283

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine
Description: effect of lidocaine on sweat production during exercise in the heat

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: control
Description: one arm will be pretreated with topical lidocaine, the other arm will not
Study: NCT04390503

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Convalescent Plasma (anti-SARS-CoV-2 plasma)
Description: Convalescent Plasma that contains antibody titers against SARS-CoV-2.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Control (albumin 5%)
Description: Albumin (Human) 5% is a sterile aqueous solution for intravenous use containing the albumin component human plasma.
Study: NCT06622512

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radial Pressure Wave Therapy
Description: Radial pressure wave therapy (RPWT) is a non-invasive treatment used for musculoskeletal disorders, including knee OA. (Schroeder AN) It involves the application of mechanical energy to stimulate biological responses, RPWT differs fundamentally from focal shock wave therapy (FSWT) in several physical properties, in its point of maximum energy flux density (EFD), and in some clinical applications. RPWT activates cellular pathways involved in tissue regeneration and generates mechanical energy that spreads radially from the point of application, primarily affecting superficial tissues and leading to pain relief and improved function through a process known as mechano-transduction, by enhancing blood flow and stimulating cellular repair processes . (Simplicio CL, Wang CJ)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radial Pressure Wave Therapy
Description: Radial pressure wave therapy (RPWT) is a non-invasive treatment used for musculoskeletal disorders, including knee OA. (Schroeder AN) It involves the application of mechanical energy to stimulate biological responses, RPWT differs fundamentally from focal shock wave therapy (FSWT) in several physical properties, in its point of maximum energy flux density (EFD), and in some clinical applications. RPWT activates cellular pathways involved in tissue regeneration and generates mechanical energy that spreads radially from the point of application, primarily affecting superficial tissues and leading to pain relief and improved function through a process known as mechano-transduction, by enhancing blood flow and stimulating cellular repair processes . (Simplicio CL, Wang CJ)
Study: NCT05807074

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic Acid
Description: Applied intraoperatively

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Saline
Description: Applied intraoperatively
Study: NCT04661280

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Donepezil
Description: Donepezil 5 mg per day during one month, then 10 mg per day during 5 months.
Study: NCT04860973

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Weighted blankets
Description: Weighted blankets given to patient for 7 days/nights
Study: NCT05567653

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 (Sanprobi Stress)
Description: 3-month, multi-strain probiotic supplementation (one a day, 3 x 10⁹ CFU)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Starch (placebo)
Description: 3-month placebo
Study: NCT06700915

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Diaberine
Description: Participants will take one capsule three times daily, 15 minutes prior to meals, over a 24-week period.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Capsule
Description: Participants will take one capsule three times daily, 15 minutes prior to meals, over a 24-week period.
Study: NCT06698887

Intervention type: DRUG
Intervention: Idecabtagene vicleucel
Description: As per CA089-1043 study protocol
Study: NCT06722261

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategic and Interactive Signing Instruction
Description: Evidence-based instructional methods, grounded in cognitive, sociocultural, and linguistic theories, are applied to interventions that support sign language development in deaf children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategic and Interactive Signing Instruction
Description: Evidence-based instructional methods, grounded in cognitive, sociocultural, and linguistic theories, are applied to interventions that support sign language development in deaf children.
Study: NCT04632069

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: N acetyl cysteine + vagus nerve stimulation
Description: NAC x 14 days, taVNS x 10 days
Study: NCT06724510

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HIFU treatment with ULTRAFOMER MPT
Description: The high-intensity focused ultrasound (HIFU) treatment, which is the primary intervention being evaluated for efficacy and safety in eyebrow lifting.
Study: NCT06730373

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab Vedotin
Description: 2.5 mg/kg IV every 3 weeks
Study: NCT04770220

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental: ALZ-801
Description: ALZ-801 tablet 265 mg BID
Study: NCT06730373

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 200 mg IV every 3 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sintilimab
Description: 200 mg IV every 3 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-1
Description: 40-60 mg BID for 14 days, every 3 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Trastuzumab
Description: First load dose is 8.0mg/kg , then 6.0 mg/kg IV every 3 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin
Description: 130 mg/m2 Q3W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: 1000 mg/m² Q3W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5-FU
Description: 800 mg/m²

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: 80 mg/m²
Study: NCT06724991

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lower Dose Therapy
Description: The group receiving the lower-dose therapy consists of 5 units of Actrapid (insulin) with 25cc of Dextrose 50%. This intervention is the focus of the clinical trial and is being investigated to determine if it achieves a comparable reduction in potassium levels with fewer potential complications. The aim is to establish it as a non-inferior alternative to conventional-dose therapy in the management of mild and moderate hyperkalemia.
Study: NCT04770220

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: Placebo
Description: Placebo tablet BID
Study: NCT06448507

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: INJEX [Needle less anesthesia]
Description: already described

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Syringe Needle [ Traditional technique]
Description: described
Study: NCT05997069

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Posterior-anterior vertebral mobilizations followed by Prone press-up exercise
Description: Posterior-anterior vertebral mobilizations of the lumbar spine are achieved by applying a force on to a spinous process in a posteroanterior direction (Back to front).~Prone press-up exercise is started in the prone position (lying on stomach) on a flat surface. Participant keeps hands underneath the shoulders then press up his or her upper body while trying to keep the hips on the floor.
Study: NCT05303142

Intervention type: OTHER
Intervention: Heat Tolerance Assessment
Description: 60-90 minutes exercise in hot (34 °C; 45% R.H.) conditions at 60%VO2max

Intervention type: OTHER
Intervention: Heat Tolerance Assessment
Description: 60-90 minutes exercise in hot (34 °C; 45% R.H.) conditions at 60%VO2max
Study: NCT06724991

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Dose Therapy
Description: The group receiving the conventional-dose therapy, consisting of 10 units of Actrapid (insulin) with 50cc of Dextrose 50%, which is currently in use as a standard practice in emergency departments for managing mild and moderate hyperkalemia. This dosing regimen aligns with established clinical guidelines and is widely accepted as an effective approach in controlling potassium levels.
Study: NCT06732921

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alertwatch - Recovery Control Tower
Description: Decision-support software, customized for the PACU environment, Interaction between the telemedicine center and the PACU
Study: NCT06733090

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.12% chlorhexidine glucanate solution
Description: The superiority of two different solutions over each other will be examined with a standard maintenance.
Study: NCT05997069

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy
Description: Traditionally used physiotherapy for the treatment of nonspecific low back pain (thermotherapy and general stretching exercises)
Study: NCT06059014

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 177Lu-PSMA-1 (radiopharmaceutical)
Description: 7.4 GBq (or 5.9 GBq in case of lower actvity) of 177Lu-PSMA-1, every 6 weeks for 4 administirations
Study: NCT06068673

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clindamycin 600 mg
Description: Clindamycin 900 - 1200 mg TWICE per day during 2 weeks period.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard regimen
Description: standard regimen
Study: NCT06478966

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental
Description: Stoma care training was delivered using the PechaKucha method for the intervention group.The presentation format involves 20 slides (usually containing images only) that are shown for 20 seconds each, for a total presentation length of 6 minutes and 40 seconds.
Study: NCT04747886

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: WW Only
Description: WW is a structured behavioral weight management program that focuses on diet, physical activity and mindset skills. The dietary approach is based on creating an energy deficit diet to produce weight loss while also being attentive to the quality of the calories. Specifically, the WW program assigns SmartPoints values to foods based on calories, sugar, saturated fat and protein. In addition, particular foods are assigned a points value of zero (0) to encourage a healthier eating pattern (e.g. fruits, vegetables, non-fat yogurt, fish).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WW + PolyRules!
Description: In addition to WW, participants will be asked to engage in daily cognitive training using the PolyRules! app for three months. They will be instructed to start with 20-min of daily cognitive training and to progressively increase their training time to 30-min.
Study: NCT06578507

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxycarbamid
Description: Hydroxycarbamide Paediatric dispersible tablets will be provided in the form of film-coated dispersible tablets containing 50 mg of hydroxycarbamide.~The IMP will be administered as half-strength twice daily, based on the body weight of the patient.
Study: NCT06576310

Intervention type: DEVICE
Intervention: Mandibular Advancement Device
Description: In this research, participation in the protocol seamlessly integrates into routine care at the Odontology Department of the University Hospital of Toulouse. The visits include the provision of the orthosis at 3 weeks (T1), with EMGs and digital occlusal analysis. The 6-week follow-up visit (T2) adjusts therapeutic propulsion, subjectively resolving symptoms related to OSAS. At the T0 visit, the researchers collect the polysomnographic monitoring before fitting the orthosis (carried out in the patient's reference sleep laboratory) to assess treatment efficiency. The end-of-research visit (6 months after T1) comprehensively collects data, including questionnaires on stress, anxiety, sleep quality and quantity, oral habits, temporo mandibular dysfunction pain, and quality of life. Moreover, the researchers collect the polysomnographic monitoring after 3 months fitting the orthosis (carried out in the same patient's reference sleep laboratory than before fitting the orthosis).
Study: NCT06574594

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: methotrexate discontinuation group : stop MTX for 2 weeks after each shingrix vaccination

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methotrexate
Description: methotrexate continuation group : keep methotrexate
Study: NCT06576141

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kaleidoscope
Description: The participation of patients in this group in the study will take approximately 15-20 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Virtual Reality
Description: The participation of patients in this group in the study will take approximately 15-20 minutes.

Intervention type: OTHER
Group type: OTHER
Intervention: control
Description: The participation of patients in this group in the study will take approximately 5-10 minutes.
Study: NCT06335407

Intervention type: DRUG
Group type: OTHER
Intervention: Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg
Description: BXCL 501 40µg will be administered orally, as individual films in the Sub Lingual (SL) space.

Intervention type: DRUG
Group type: OTHER
Intervention: Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg
Description: BXCL 501 80µg will be administered orally, as individual films in the SL space
Study: NCT05736120

Intervention type: OTHER
Intervention: No treatment given
Description: No treatment given

Intervention type: OTHER
Intervention: No treatment given
Description: No treatment given
Study: NCT05234125

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Better
Description: It is a nonpharmacologic sleep intervention to improve maternal glucose metabolism in African American Pregnant Women (AAPW). Sleep BETTER is composed of sleep hygiene practices and cognitive-behavioral principles.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Birth Prep
Description: The intervention involves training about pregnancy-related issues, and follow up
Study: NCT06188871

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Two injections of 300mg dupilumab, subcutaneous 14 days apart
Study: NCT05393648

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Accelerated Theta Burst Stimulation
Description: Cool B65- A/P - active side magnetic coil stimulation applied to the left dorsal lateral prefrontal cortex.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham accelerated Theta Burst Stimulation
Description: Cool-B65 A/P - sham side magnetic coil stimulation applied to the left dorsal lateral prefrontal cortex.
Study: NCT05137782

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Specialty Palliative Care
Description: Specialty palliative care, as opposed to primary palliative care.