TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06383312

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Reflexologic Magnetic Insole Group
Description: Reflexologic magnetic insole will be used for at least 7 hours a day, every day, for 12 weeks in participants diagnosed with primary dysmenorrhea. Then the effectiveness of the insoles will be compared.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Orthopedic Insole Group
Description: Orthopedic insole (sham) will be used for at least 7 hours a day, every day, for 12 weeks in participants diagnosed with primary dysmenorrhea. Then the effectiveness of the insoles will be compared.
Study: NCT06085885

Intervention type: DEVICE
Intervention: Cochlear implant
Description: Cochlear implant
Study: NCT05796206

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MIL62
Description: An intravenous (IV) infusion of 1000 mg of MIL62 will be administered at W1D1、W3D1、W25D1、W27D1、W53D1、W55D1.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: An intravenous (IV) infusion of placebo will be administered at W1D1、W3D1、W25D1、W27D1、W53D1、W55D1.
Study: NCT05161013

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: LINFU™
Description: A method to detect pancreatic cancer (ductal adenocarcinoma) using ultrasound technology in those who are at significantly increased risk for developing pancreatic cancer. LINFU™ involves analysis of pancreatic fluid collected.
Study: NCT02051543

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Behavioral Treatment of Insomnia -Military Version
Study: NCT05687071

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 180mg of ETC-1002(bempedoic acid)
Description: 180mg, tablet, once daily, for 52 weeks
Study: NCT05220826

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Post surgical embolization of middle meningeal artery with liquid embolic agents (ethylene vinyl alcohol copolymers as Onix, Squid, Phil or Libro)
Description: The endovascular procedure will be performed until 72 hours after surgical evacuation of chronic subdural hematoma. Embolization will be performed with non-adhesive embolizing fluids such as Onix®, Phil®, Squid® or Libro®.
Study: NCT05158764

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Venous compression system of the lower limbs stage C6 / C6r of the CEAP classification
Description: Etiological treatment of venous disease of the lower limbs stage C6 / C6r
Study: NCT04543643

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carvedilol
Description: As the third generation of NSBB, carvedilol is more effective in reducing HVPG than propranolol, which is recommended by Baveno VI as the first-line drug for EVB primary prevention.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carvedilol
Description: As the third generation of NSBB, carvedilol is more effective in reducing HVPG than propranolol, which is recommended by Baveno VI as the first-line drug for EVB primary prevention.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berberine
Description: Berberine can regulate the intestinal flora, which is safe and effective in clinical application.
Study: NCT05065502

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Academic Detailing (AD)
Description: The National Resource Center for Academic Detailing (NaRCAD) describes AD as an innovative, one-on-one outreach education technique that helps clinicians provide evidence-based care to their patients. Using an accurate, up-to-date synthesis of the best clinical evidence in an engaging format, academic detailers ignite clinician behavior change, ultimately improving patient health. A successful AD visit is highly interactive, always a dialogue, and assesses a clinician's individual needs, beliefs, attitudes, issues, and concerns in order to promote better.\[practice\].

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Academic Detailing (AD)
Description: The National Resource Center for Academic Detailing (NaRCAD) describes AD as an innovative, one-on-one outreach education technique that helps clinicians provide evidence-based care to their patients. Using an accurate, up-to-date synthesis of the best clinical evidence in an engaging format, academic detailers ignite clinician behavior change, ultimately improving patient health. A successful AD visit is highly interactive, always a dialogue, and assesses a clinician's individual needs, beliefs, attitudes, issues, and concerns in order to promote better.\[practice\].

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LEAP
Description: Learn. Engage. Act. Process (LEAP) program is a structured 6-month core curriculum plus 6 monthly collaborative sessions. The LEAP quality improvement program engages frontline teams in sustained incremental improvements of EBPs over a six-month period, allowing space for busy clinicians to learn and immediately apply fundamental QI skills. LEAP encompasses: 1) a structured, accessible curriculum based on the Institute for Healthcare Improvement's (IHI) Model for Improvement and Plan-Do-Study-Act cycles of change; 2) team-based, hands-on learning, and 3) coaching support and a QI network to enhance learning and accountability.
Study: NCT03682523

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sedentary behavior reduction intervention
Description: Participants will be provided with a device to measure physical activity and sedentary behaviours. A tablet will be in the research office and each afternoon, it will be synced to the device to assess the activity progress of the patient. The research team will deliver an upright time goal and will target a 20% increase in upright time from the previous hospital day. Physiotherapist research assistants will visit the participants every afternoon to monitor progress and safely mobilize participants to their maximum ability if they have not met their daily goal (including weekend). The maximum level of ability will be determined in consultation with the healthcare team. Participants who do not meet their goal will be mobilized in the late afternoon/ early evening.
Study: NCT05690529

Intervention type: PROCEDURE
Intervention: Ablation
Description: Radiofrequency AF ablatoon

Intervention type: PROCEDURE
Intervention: Ablation
Description: Radiofrequency AF ablatoon
Study: NCT05622526

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group 1 or Experimental group
Description: Capsules of fecal microbiota transplantation

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Group 2 or Control group
Description: capsules of placebo
Study: NCT05290025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine patch
Description: \> 20 cigarettes per day: 21 mg nicotine/ 24 hours 10-20 cigarettes per day: 14 mg nicotine/ 24 hours 5-10 cigarettes per day: 7 mg nicotine/ 24 hours

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine gum
Description: Nicotine chewing gum will be available in 1 and 2 mg strengths. Patients may individually choose which strength to use. Maximum 12 chewing gums per day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine lozenge
Description: Nicotine lozenges will be available in 1 and 2 mg strengths. Patients may individually choose which strength to use. Maximum 12 lozenges per day

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking cessation counselling
Description: Once a week patients are asked about progress in cessation attempt. Sigaretts smoked the last week are recorded. Goal is set for the next week. Information on typical nicotine withdrawal symptoms and ameliorating techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Screening for use of tobacco products
Description: At the initiation of the trial screening questions about cigarett use for the last day and week.

Intervention type: OTHER
Group type: OTHER
Intervention: Screening for use of tobacco products
Description: At the initiation of the trial screening questions about cigarett use for the last day and week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Screening for interest in smoking cessation
Description: At the initiation of the trial all smoking participants are asked if the are interested in changing their smoking habits. They are given three alternatives: will make cessation attempt; will make reduction attempt; not certain.

Intervention type: OTHER
Group type: OTHER
Intervention: Screening for interest in smoking cessation
Description: At the initiation of the trial all smoking participants are asked if the are interested in changing their smoking habits. They are given three alternatives: will make cessation attempt; will make reduction attempt; not certain.
Study: NCT05284123

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-compassion workshop
Description: The self-compassion workshop instructs participants to reflect on a source of shame, connect with their suffering related to it, and then direct feelings of support and understanding towards their suffering via a few brief writing tasks. This workshop also provides participants with basic information about mental health resources.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mental health literacy workshop
Description: The mental health literacy workshop provides participants with information about the symptoms and treatment of common mental disorders, and asks participants to reflect on what they learned through a couple brief writing tasks. This workshop also provides participants with basic information about mental health resources.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control workshop
Description: The control workshop provides participants with basic information about mental health resources.
Study: NCT05609890

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Supplement
Description: Supplement: a mixture of saffron, tea extract, lemon balm and valerian.~Dose: The participant will take one sachet every day, one hour before going to bed, for six weeks.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo sachet~Dose: The participant will take one sachet everyday, one hour before going to bed, for six weeks.
Study: NCT05093400

Intervention type: OTHER
Intervention: no intervention
Description: saliva collection
Study: NCT05482685

Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Conduct a 10-minute survey

Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Conduct a 10-minute survey

Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Conduct a 10-minute survey

Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Conduct a 10-minute survey
Study: NCT05158764

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Venous compression system of the lower limbs stage C6 / C6r of the CEAP classification
Description: Etiological treatment of venous disease of the lower limbs stage C6 / C6r
Study: NCT06163508

Intervention type: DRUG
Intervention: Q-Cells®
Description: Long term observational study of patients who received 1 of 3 different amounts of Q-Cells®.

Intervention type: DRUG
Intervention: Q-Cells®
Description: Long term observational study of patients who received 1 of 3 different amounts of Q-Cells®.

Intervention type: DRUG
Intervention: Q-Cells®
Description: Long term observational study of patients who received 1 of 3 different amounts of Q-Cells®.
Study: NCT05397158

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: single administration of low dose polyethylene glycol
Description: Patients in single administration of low dose polyethylene glycol (PEG) group: Take 30ml lactulose and 2L PEG.~Patients in control group: Take 4L PEG.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: single administration of low dose polyethylene glycol
Description: Patients in single administration of low dose polyethylene glycol (PEG) group: Take 30ml lactulose and 2L PEG.~Patients in control group: Take 4L PEG.
Study: NCT05111730

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Shock wave Therapy.
Description: Shockwave therapy is a multidisciplinary device used in orthopedics, physiotherapy, sports medicine, urology and veterinary medicine. Its main assets are fast pain relief and mobility restoration. Together with being a non-surgical therapy with no need for painkillers makes it an ideal therapy to speed up recovery and cure various indications causing acute or chronic pain. Shockwave is an acoustic wave which carries high energy to painful spots and myoskeletal tissues with sub-acute, sub-chronic and chronic conditions. The energy promotes regeneration and reparative processes of the bones, tendons and other soft tissues. Shockwaves are characterized by jump change in pressure, high amplitude and non-periodicity. The kinetic energy of the projectile, created by compressed air, is transferred to the transmitter at the end of the applicator and further into the tissue.
Study: NCT05048966

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group Wellness Class 1
Description: Twelve weekly online group wellness sessions for individuals with the disability and their support person. Each class will last for approximately 2 hours.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Group Wellness Class 2
Description: Twelve weekly online group wellness sessions for individuals with the disability and their support person. Each class will last for approximately 2 hours.
Study: NCT05091398

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regional analgesia of thoracic surgical patients
Description: ultrasound-guided erector spinae block on T4 and T6 levels ,paravertebral block or intercostal nerve block after the anesthesia induction and turning the patient in the lateral position with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regional analgesia of thoracic surgical patients
Description: ultrasound-guided erector spinae block on T4 and T6 levels ,paravertebral block or intercostal nerve block after the anesthesia induction and turning the patient in the lateral position with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .
Study: NCT06380413

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tai Chi Chuan Plus Walking
Description: Participants perform a 12-week program with two weekly sessions on non-consecutive days. The sessions last 75 min (5 min of warm-up, 45 min of Tai Chi Chuan (TCC), 20 min of walking, and 5 min of cool-down). The intervention occurs at the School of Physical Education, Federal University of Pelotas. The TCC section occurs in a mirrored dance studio, while walking occurs on an indoor sports court. The TCC sections are based on the simplified Yang 16-movement form. Over the 12 weeks, participants learn the fundamentals and basic principles of TCC and practice the 16 movements. In the walking sections, the intensity of the effort and recovery periods are controlled through the Rate of Perceived Exertion (RPE) using the Borg scale 6-20. Effort and recovery periods are on 13 and 11 RPE, respectively. The effort and recovery lengths vary over the weeks. The training sessions are collective, with 5 to 20 participants, supervised by two experienced instructors, a TCC and a fitness instructor.
Study: NCT05091398

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regional analgesia of thoracic surgical patients
Description: ultrasound-guided erector spinae block on T4 and T6 levels ,paravertebral block or intercostal nerve block after the anesthesia induction and turning the patient in the lateral position with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .
Study: NCT06380413

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walking
Description: Participants perform a 12-week training program with two weekly exercise sessions on non-consecutive days. The sessions last 30 minutes (5 minutes of warm-up, 20 minutes of walking, and 5 minutes of cool-down) throughout the intervention period. The intervention occurs in an indoor sports court at the School of Physical Education, Federal University of Pelotas. In the walking sections, the intensity of the effort and recovery periods are controlled through the Rate of Perceived Exertion (RPE) using the Borg scale 6-20. Effort and recovery periods are on 13 and 11 RPE, respectively. The effort and recovery lengths vary over the weeks. The training sessions are collective, with 5 to 20 participants, supervised by two experienced instructors, a TCC and a fitness instructor.
Study: NCT05574413

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate intensity continuous exercise
Description: Participants will perform an acute bout of continuous cycling at 70% of the power output at lactate threshold until an energy expenditure of 350 kcal is achieved. Blood samples will be obtained immediately before and immediately, 30, and 90 minutes after exercise.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High intensity continuous exercise
Description: Participants will perform an acute bout of continuous cycling at 10% of the difference between lactate threshold and VO2peak until an energy expenditure of 350 kcal is achieved. Blood samples will be obtained immediately before and immediately, 30, and 90 minutes after exercise.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High intensity interval exercise
Description: Participants will perform an acute bout of interval cycling at at 10% of the difference between lactate threshold and VO2peak until an energy expenditure of 350 kcal is achieved. Blood samples will be obtained immediately before and immediately, 30, and 90 minutes after exercise.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Resting (no exercise) control
Description: Participants will remain in a rested state (i.e., no exercise) for the entire session. Blood samples will be obtained at the same time-points as the exercise sessions.
Study: NCT05405686

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutropin alfa
Description: addition of recombinant luteinizing hormone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Follitropin alfa
Description: recombinant follicle stimulating hormone (FSH)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follitropin alfa
Description: recombinant follicle stimulating hormone (FSH)

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Endometrial biopsy
Description: pipelle de cornier biopsy

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Endometrial biopsy
Description: pipelle de cornier biopsy
Study: NCT06443931

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cryoablation of intercostal nerves
Description: Patients in the CryoINB group will undergo cryoablation of the intercostal nerves, at the end of surgery before weaning from CPB, using the ArtiCue device for 120 seconds at a temperature of -50°C to -70°C, in the intercostal spaces where the surgical approach is located, one intercostal space above and one below it. Cold leads to axonotmesis, in which the axon and myelin sheath are damaged, preventing the pain signal from traveling along the sensory nerve. However, the structural elements of the nerve are preserved, which promotes complete regeneration at a rate of 1-2 mm per day, thereby restoring normal function within several months.
Study: NCT06291519

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-sensory Stimulation Method-Mother Applying the Method to the Baby
Description: In the multisensory stimulus method;~1. st stimulus (sense of taste): The mother breastfed the baby for 20 minutes. Breastfeeding was terminated before vaccination.~2. nd stimulus (sense of touch),: The mother applied touch - a light massage for 5 min until the vaccination process. There was a break just before the vaccination. The application was continued for another 5 min after the vaccination.~3. rd stimulus: Speech-Sound (sense of hearing): The mother spoke to the baby in a soft tone for 5 minutes until the vaccination (words, lullabies, songs, etc.). There was a break just before the vaccination. The practice was continued for 5 minutes immediately after the vaccination.~4. Stimulus Eye contact (sense of sight): The mother made eye contact with the baby in the mother's field of vision for 5 minutes until the vaccination. There was a break just before the vaccination. The application continued for another 5 minutes after the vaccination.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-sensory Stimulation Method-Nurse Applying the Method to the Baby
Description: In the multisensory stimulus method;~1. st stimulus (sense of taste): The mother breastfed the baby for 20 minutes. Breastfeeding was terminated 5 min before vaccination.~2. nd stimulus (sense of touch),: The nurse applied touch - a light massage for 5 minutes until the vaccination. There was a break just before the vaccination. The application was continued for another 5 min after the vaccination.~3. rd stimulus: Speech-Sound (sense of hearing): The nurse spoke to the baby in a soft tone for 5 minutes until the vaccination (words, lullabies, songs, etc.). There was a break just before the vaccination. The practice was continued for 5 minutes immediately after the vaccination.~4. Stimulus Eye contact (sense of sight): The nurse made eye contact with the baby in the mother's field of vision for 5 minutes until the vaccination. There was a break just before the vaccination. The application continued for another 5 minutes after the vaccination.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breastfeeding Applied Group
Description: Multisensory stimulus method not applied:~The baby was breastfed by its mother for 20 minutes. Breastfeeding was stopped just before the vaccination.
Study: NCT05504642

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pre-Chemo-radio-immunotherapy Treatment (Nivolumab/Ipilimumab)
Description: Two weeks before start of Chemo-radio-immunotherapy one administration of Nivolumab 3 mg/kg and Ipilimumab 1 mg/kg IV over 30 minutes, with a 30 minute break between Nivolumab and Ipilimumab.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Concurrent Chemo-radio-immunotherapy (Nivolumab/Ipilimumab)
Description: In week 1-7, standard administration of concurrent Cisplatin mono 40mg/m2 body surface area d1, 8, 15, 22, 29 (Monday of each treatment week) during radiotherapy. Simultaneous application of Nivolumab 3mg/kg week 1, 3, 5, 7 (on Thursday) and Ipilimumab 1mg/kg in week 5 (on Thursday).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Maintenance Treatment (Nivolumab/Ipilimumab)
Description: For six months after Chemo-radio-immunotherapy, Nivolumab 3mg/kg every two weeks x12 (week +2, +4, +6, +8, +10, +12, +14, +16, +18, +20, +22, +24 (twelve applications), each application over 30 minutes and Ipilimumab every six weeks x4 (week +6,+12, +18, +24).
Study: NCT05876052

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hypothermic oxygenated Perfusion - HOPE
Description: HOPE will start by flushing the organ at low flow values (30 ml/min) with new oxygenated perfusion fluid during back-table preparation. Organ will be treated with continuous HOPE until transplant. Organ perfusion will be continuously monitored. Minimal perfusion time will be 1 hour for livers.