TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06541002

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SHIFT Intervention Group
Description: Participants assigned to SHIFT will meet with their HCT clinician for a brief medical examination to assess the need for medications for erectile dysfunction, vaginal atrophy, or genital graft-versus-host disease; and start using SHIFT at their desired pace over 8 weeks to complete five modules.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care Group
Description: Participants assigned to the enhanced usual care group will meet with their HCT clinician for a brief medical examination to assess the need for medications for erectile dysfunction, vaginal atrophy, or genital graft-versus-host disease; and maybe referred to a psychologist, urologist, or gynecologist at the participants' request or at the discretion of the HCT clinician.
Study: NCT06023758

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN026
Description: KN026：30 mg/kg Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN026
Description: KN026：30 mg/kg Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN046
Description: KN046：5 mg/kg Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN046
Description: KN046：5 mg/kg Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XELOX
Description: Oxaliplatin 130mg/m2 d1，Capecitabine 1000mg/m2 d1-14，Q3W
Study: NCT05039931

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GNC-035
Description: Administration by intravenous infusion.
Study: NCT05832242

Intervention type: OTHER
Intervention: Ultrasound
Description: Point-of-care ultrasound in the emergency department

Intervention type: OTHER
Intervention: Ultrasound
Description: Point-of-care ultrasound in the emergency department
Study: NCT05863754

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Networked Neuroprosthesis Device
Description: The Networked Neuroprosthesis Device is an implantable, configurable neuromodulation platform that provides functional movement by the coordinated activation of peripheral neural pathways activating innervated paralyzed muscles, and sensing of physiological signals.
Study: NCT05949983

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: APA Program
Description: Patients treated and monitored for their breast cancer following the 6-month APA program.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Recommendations for physical activity
Description: Patients treated and monitored for their breast cancer who have received recommendations for physical activity as well as a 6-month activity schedule. To facilitate patient acceptance and participation in this study, patients who will be randomized to the control group will be offered to follow the APA program after one year of inclusion
Study: NCT05055674

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motherly app
Description: The Motherly app is organized in four different modules: 1) Library: a collection of brief texts on several topics related to health and pregnancy, 2) Health: journeys with varying degrees of interactivity designed to teach and engage participants in well-established psychological techniques (behavioral activation, cognitive restructuring, emotion regulation, stress management techniques, mindfulness and meditation, sleep hygiene techniques), 3) Pregnancy and motherhood: a module to help mothers keep track of their health care visits, medical exams, and their childrens' development, and 4) Profile: a module allowing participants to keep track of activities and goals completed in the Health module journeys, and to assess depression and anxiety symptoms with brief questionnaires, with results displayed graphically in a timeline and in the the form of short feedback texts.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: COMVC app
Description: The COMVC displays over 30 brief psychoeducational videos on several topics related to general mental health, such as depression, anxiety, stress, sleep, problem solving techniques, among others. Psychoeducation is limited to video only (no interactivity). The content of these videos was developed by clinicians, researchers, and professors from the Psychiatry Department of the Medical School of the University of Sao Paulo and from the Federal University of Rio Grande do Sul. Mental health monitoring is delivered by means of brief questionnaires assessing depression and anxiety symptoms, which can be filled at users' discretion. Users' responses are displayed graphically in a timeline and they receive short feedback texts based on assessment results.
Study: NCT05192577

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrical stimulation
Description: At the beginning of the session, an electrode will be attached to the participant's ankle. Electrical stimulation will be applied to estimate the electrical perception threshold. This threshold will be used as condition stimuli when different thermal thresholds are assessed.
Study: NCT04926675

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological Therapy
Description: Participants will be receiving their one-to-one psychological therapy from IAPT as usual. They typically receive between 6 and 12 sessions with a psychological practitioner.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Debt Advice
Description: Participants will receive one-to-one support from a Citizen's Advice (CA) money advisor for as long as needed to resolve any money worries currently affecting their mental health.
Study: NCT05954234

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Postural re-education
Description: Each session of the experimental approach will be composed of 40 minutes of postural exercise. Participants will be asked to maintain two different postures to stretch both the anterior and posterior muscle chains. The first posture will consist of lying on the back maintaining the extension of the legs to release the respiratory diaphragm and stretch the anterior muscle chain. For the second posture, participants wiil be asked to lie on their back with their legs flexed to stretch the posterior chai. For each posture, the physical therapist will use verbal commands and manual contact to maintain alignment and make the necessary postural corrections to optimize the stretching and discourage compensatory movements.~10 sessions of the allocated intervention will be performed and organized in 2 times a week for 5 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal mobilization
Description: This approach will consist of 40 minutes of thoracolumbar spine mobilization. Two different mobilizations will be carried out. In the first one the patient will be in sitting position with both legs out of the bed and a mobilization in antero-posterior direction will be provide by the physiotherapist; the second one will consist in rotational mobilisation provide with the patient in lateral decubitus position.~10 sessions of the allocated intervention will be performed and organized in 2 times a week for 5 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Perineal Exercises
Description: Perineal Exercises will be performed in both the allocated approach. The protocol will consist in 10 minutes of perineal contraction and relaxation and 10 minutes of stretch-reflex for a total of 20 minutes of perineal exercises.10 sessions of the allocated intervention will be performed and organized in 2 times a week for 5 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Perineal Exercises
Description: Perineal Exercises will be performed in both the allocated approach. The protocol will consist in 10 minutes of perineal contraction and relaxation and 10 minutes of stretch-reflex for a total of 20 minutes of perineal exercises.10 sessions of the allocated intervention will be performed and organized in 2 times a week for 5 weeks.
Study: NCT06449781

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutetium (177Lu) vipivotide tetraxetan
Description: The intervention will consist of a single administration of 7,4 GBq of lutetium (177Lu) vipivotide tetraxetan
Study: NCT06462690

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pre-mid-post test
Description: (PIF) (DLQI) (GCS) Data Collection Forms Humidity measurement with DMM device
Study: NCT06176027

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacytidine plus CAOLD regimen
Description: Patients were treated by Azacytidine(75 mg/m2 on days 1-7) plus CAOLD regimen (cyclophosphamide 400mg/m2 qd d1; cytarabine 30mg/m2 qd d1-d4; vindesine 2mg/m2 qd d1; pegaspargase 2500iu/m2 qd d2; dexamethasone 7.5mg/m2 qd d1-d5)
Study: NCT06050408

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 1hz repetitive transcranial magnetic stimulation
Description: 1hz rTMS applied over P3 EEG 10-20 location. Total of 1200 pulses administered. Figure of eight coil used to stimulate, held tangential to the scalp.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 1hz repetitive transcranial magnetic stimulation
Description: 1hz rTMS applied over P3 EEG 10-20 location. Total of 1200 pulses administered. Figure of eight coil used to stimulate, held tangential to the scalp.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 1hz repetitive transcranial magnetic stimulation
Description: 1hz rTMS applied over P3 EEG 10-20 location. Total of 1200 pulses administered. Figure of eight coil used to stimulate, held tangential to the scalp.
Study: NCT05457309

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: malignant fungating wounds care regimen
Description: 1) Preliminary construction of regimen: The researchers summarized the literatures and guidelines about malignant fungating wounds care, and then formed a preliminary draft of the regimen.2) Expert consultation: Experts in malignant fungating wound care, breast cancer and rehabilitation were consulted by email, and the researchers revised the protocol according to the experts' comments, and the final draft was determined after multiple rounds of consultation with experts. 3) Pre-experiment: The researchers investigated the enrolled patients to assess the feasibility of the protocol, and adjusted the content based on the feedback.4) Final Determining: including health records establishment, the intervention time, implementers, location, method and frequency. A wound care team was formed, interventions were carried out in terms of somatic care, wound home care, psychological support, and rehabilitation guidance, and the enrolled patients would be regularly followed by the researchers.
Study: NCT05459870

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 4SCAR T cells
Description: Infusion of 4SCAR T cells at 10\^6 cells/kg body weight via IV
Study: NCT05430789

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: 5As brief advice
Description: Participants will receive brief face-to-face advice following a 5As model at baseline:~1. Ask: Smoking patients will be asked about their smoking status.~2. Advise: Smoking patients will be advised to quit in a clear and personalised manner, with a focus on smoking-related diseases.~3. Assess: Smoking patients will be assessed for their readiness to quit by assessing their self-efficacy and perceived importance.~4. Assist: Those who are ready to quit will be assisted in setting a quit plan.~5. Arrange: Refer to smoking cessation services.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5As brief advice
Description: Participants will receive brief face-to-face advice following a 5As model at baseline:~1. Ask: Smoking patients will be asked about their smoking status.~2. Advise: Smoking patients will be advised to quit in a clear and personalised manner, with a focus on smoking-related diseases.~3. Assess: Smoking patients will be assessed for their readiness to quit by assessing their self-efficacy and perceived importance.~4. Assist: Those who are ready to quit will be assisted in setting a quit plan.~5. Arrange: Refer to smoking cessation services.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-help e-booklet
Description: A 12-page generic self-help smoking cessation e-booklet via IM apps, including:~1. Highlights of the absolute risk of death due to smoking;~2. Smoking and diseases management;~3. Ten horrible pictorial warnings of health consequences of smoking and second-hand smoking;~4. Benefits of quitting;~5. Methods to quit and handle. withdrawal symptoms.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-help e-booklet
Description: A 12-page generic self-help smoking cessation e-booklet via IM apps, including:~1. Highlights of the absolute risk of death due to smoking;~2. Smoking and diseases management;~3. Ten horrible pictorial warnings of health consequences of smoking and second-hand smoking;~4. Benefits of quitting;~5. Methods to quit and handle. withdrawal symptoms.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-led mHealth intervention
Description: Participants will receive real-time mHealth behaviour and psychosocial support for 12 weeks after baseline through IM apps. mHealth intervention consists of two main parts: regular instant messaging on smoking cessation and personalized real-time mHealth chatting on smoking and disease (including active referral to smoking cessation service)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Regular intervention
Description: Participants will receive text messages using IM app with content on general health and reminding the importance of participating in the follow-up surveys and biochemical validation for quitting.
Study: NCT05617846

Intervention type: OTHER
Intervention: Anti-osteoporosis therapy
Description: Bone healing, limb function, and complications of postoperative osteolysis in patients with bone tumors of the extremities treated with anti-osteoporosis therapy.
Study: NCT05388890

Intervention type: DRUG
Intervention: MLD
Description: Modified Liujunzi Decoction is provided by the chinese pharmacy of Peking University First Hospital , one dose per day, taken in twice, and the course of treatment is 6 months.

Intervention type: DRUG
Intervention: WFC
Description: Chinese patent medicine, take according to the instructions, the course of treatment is 6 months.
Study: NCT05668793

Intervention type: DIAGNOSTIC_TEST
Intervention: GNB4 and Riplet Gene Methylation Combined Detection Kit (Fluorescent PCR Method)
Description: Blood samples from participants in the group were collected and methylation tests were performed according to the kit instructions.

Intervention type: DIAGNOSTIC_TEST
Intervention: GNB4 and Riplet Gene Methylation Combined Detection Kit (Fluorescent PCR Method)
Description: Blood samples from participants in the group were collected and methylation tests were performed according to the kit instructions.
Study: NCT05443477

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hericium Erinaceus Mycelium
Description: participants received two oral capsules containing Hericium erinaceus Mycelium every day for the 3 months.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: participants received two oral capsules containing Probiotic powder every day for the 3 months.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: control
Description: participants received two oral capsules containing control powder every day for the 3 months.
Study: NCT06103513

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Somatropin
Description: The treatment of children with subcutaneous recombinant human growth hormone (rhGH) is the current gold standard of care for children with diagnosed GHD. This study will serve only to investigate the optimal dose of treatment in the first year of treatment with rhGH.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Somatropin
Description: The treatment of children with subcutaneous recombinant human growth hormone (rhGH) is the current gold standard of care for children with diagnosed GHD. This study will serve only to investigate the optimal dose of treatment in the first year of treatment with rhGH.
Study: NCT06236035

Intervention type: DEVICE
Intervention: Analgesia nociception index
Description: a device to assess patient's pain during surgery
Study: NCT05718505

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Atmo Motility Gas Capsule System
Description: The Atmo System measures whole gut and regional gut transit times. Measurements of GI tract transit times are used for evaluating motility disorders.~Gastric emptying time (GET) is indicated for the evaluation of patients with suspected gastroparesis. Delayed GET is implicated in such disorders as idiopathic and diabetic gastroparesis and functional non-ulcer dyspepsia.~Colonic transit time (CTT) is indicated for the evaluation of colonic transit in patients with chronic constipation, to aid in differentiating slow and normal transit constipation. In the case where ileocecal junction transit cannot be determined the system will report combined Small and Large Bowel Transit Time (SLBTT).~Transit times are derived from measures of temperature, relative humidity, hydrogen concentration, and carbon dioxide concentration, in conjunction with indicators of fermentation activity, capsule tumble, and antenna reflectance. Not for use in pediatric patients.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SmartPill Monitoring System
Description: The SmartPill GI Monitoring System (Medtronic) offers a method for measuring gastric emptying time (GET), small bowel transit time (SBTT), colonic transit time (CTT), small bowel large bowel transit time (SLBTT) and whole gut transit time (WGTT) with a single test, which can be used as an aid for the diagnosis of both gastroparesis and slow transit constipation.~The SmartPill System measures pH, temperature and pressure. It is approved for use in the measurement of GI transit times by the FDA.
Study: NCT06702150

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Changing the nursing care model to the primary nursing model
Description: The nurses received training in primary nursing care before the start of the intervention. The model was tested and implemented in early April 2022. Since then, all patients admitted to the unit have been assigned to a primary nurse within the first 48 hours. This nurse is responsible for developing and monitoring the patient's care plan, assessing care needs, implementing the care plan and evaluating the outcomes. This nurse is also responsible for coordinating care needs and discharge planning with other healthcare professionals. When the primary nurse is not working, another nurse from his or her team continues the care plan that he or she has defined. All patients admitted to the unit who met the selection criteria were informed about the study and, if they agreed to take part, completed a self-care competence questionnaire at admission (baseline), at discharge and one month after discharge. They also completed a questionnaire on satisfaction with nursing care at discharge.
Study: NCT05843695

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iTCBT-I
Description: Individual format over 2 weeks
Study: NCT06247930

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D3
Description: 2000 IU per day for 6 weeks (two capsules of 800 IU plus one capsule of 400 IU), followed by 800 IU (one capsule of 800 IU) per day for 6 weeks.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Vitamin D3 placebo
Description: Three capsules for 6 weeks, followed by one capsule for 6 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mental health education
Description: The mental health education consists of providing a brochure with information about mental health problems. Additionally, participants will receive a set of 5 educational mental health videos regarding depression. Each of these videos is 15 minutes long.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Mental health education
Description: The mental health education consists of providing a brochure with information about mental health problems. Additionally, participants will receive a set of 5 educational mental health videos regarding depression. Each of these videos is 15 minutes long.
Study: NCT04865887

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200mg, every 3 weeks, IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 20 mg (2 capsules x10mg), daily, orally
Study: NCT05690464

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: magnesium glycinate supplement
Description: magnesium glycinate (480 mg/day)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo
Study: NCT05959564

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized Chatbot Intervention
Description: In this intervention, participants will first see a standard CDC HPV vaccine message. After that they will be invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which are tailored to their personalities.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Non-Personalized Chatbot Intervention
Description: In this intervention, participants will first see a standard CDC HPV vaccine message. After that they will be invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which are not tailored to their personalities.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: No Chatbot Control
Description: In this intervention, participants will see a standard CDC HPV vaccine message only and will not interact with any chatbot.
Study: NCT05758246

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fisetin-dose 1
Description: 20mg/kg once a day for one day.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fisetin-dose 2
Description: 20mg/kg once a day for two days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo treatment
Study: NCT06353113

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Down Dog Prenatal Yoga App
Description: The Down Dog prenatal yoga app launched in 2015 and was designed to align with the changes a pregnant body goes through in each trimester. Users can select a practice by trimester, which will offer modification cues to work with a changing body during pregnancy. Users can also customize their experience by boosting things like Heartburn or Pubic Symphysis so they can continue to practice yoga and omit poses that might be uncomfortable. The app also utilizes user feedback, to continuously implement new practices to better their app for user interface.~All of the prenatal yoga classes were created by a certified and experienced prenatal yoga instructor who has a 200hr yoga certification through Pure Yoga (New York), 80hr prenatal yoga certification through Prenatal Yoga Center (New Yoga), and is Trauma Informed Yoga certified through Exhale to Inhale (New York).