TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06060431

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain Science Education
Description: The Pain Science Education program consists of two workshops, 90 and 60 minutes in length, one week apart. The content of the workshops aims to provide students with information about the contemporary pain paradigm and to re-conceptualize pain.
Study: NCT05478291

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vitamin D supplementation
Description: Appropriate diet and physical activity counselling to both groups. Supplementation with Vitamin D and oral Calcium-Doses of cholecalciferol (commercial name, Calcirol) 60,000 IU (sachets, dissolved in half glass milk) once per week for eight weeks for the intervention group and placebo (Lactose granules) to the placebo group according to the random numbers generated by the computer. After every 24 weeks blood 25 (OH) D levels will be assessed. If the subjects are found to be still deficient then supplementation of cholecalciferol 60,000 IU per week for eight weeks will be repeated.If the 25 (OH) D levels are normal, then cholecalciferol supplementation in doses of 200 IU per day will be given as a maintenance dose. Equal doses of calcium carbonate (1gm per day, commercial name Calcal) will be given to both the groups.
Study: NCT05978102

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STI-7349
Description: Administered by intravenous infusion (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STI-7349
Description: Administered by intravenous infusion (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Administered by intravenous infusion (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard treatment（SoC）
Description: Depending on the treatment stage of enrolled subjects, the investigator will determine the standard treatment regimen and dosage with reference to the CSCO or other current guidelines.
Study: NCT01420666

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen
Description: Acetaminophen 325 mg, three tablets four times a day, orally, with food

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Maxigesic 325
Description: Maxigesic 325 (Acetaminophen 325 mg+ ibuprofen 97.5mg), three tablets four times a day, orally, with food
Study: NCT05124886

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderately High Oxalate (MOx) Diet
Description: Diets will contain 16% protein, 30% fat, and 54% carbohydrate, and are controlled in the amounts of calcium (400mg), oxalate (250mg), ascorbic acid (50mg), fiber (30 grams) and, other nutrients. Each controlled diet will be consumed for four days. On days of controlled diets, subjects will be provided with 2 liters of bottled water per day to ensure adequate hydration. After the controlled diet period, there will be a three-day washout period, where participants will consume Ad-lib diets supplemented with a daily intake of oxalate in the form of cooked spinach to be taken with breakfast daily for a total of 2 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Moderately High Oxalate (MOx) Diet
Description: Diets will contain 16% protein, 30% fat, and 54% carbohydrate, and are controlled in the amounts of calcium (400mg), oxalate (250mg), ascorbic acid (50mg), fiber (30 grams) and, other nutrients. Each controlled diet will be consumed for four days. On days of controlled diets, subjects will be provided with 2 liters of bottled water per day to ensure adequate hydration. After the controlled diet period, there will be a three-day washout period, where participants will consume Ad-lib diets supplemented with a daily intake of oxalate in the form of cooked spinach to be taken with breakfast daily for a total of 2 weeks.
Study: NCT01420666

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuprofen
Description: Ibuprofen 97.5mg, three tablets four times a day, orally, with food

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo, three tablets four times a day, orally, with food
Study: NCT05705661

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HIGH FREQUENCY CHEST WALL OSCILLATION
Description: The HFCWO device used a triangular wave form which increases the airflow velocity more than other devices. Therefore, clearing sticky airway mucus and alveolar exudates and maintaining airway patency has become currently the most urgent issue in the ventilatory management of patients with severe COVID-19.
Study: NCT06148025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin Oral Capsule
Description: 500mg every 6 hours for 3 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin Oral Capsule
Description: 500mg every 6 hours for 3 days
Study: NCT06026995

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PEG-rhG-CSF
Description: Subcutaneous injection with a fixed dose of 12 mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RhG-CSF
Description: Inject rhG-CSF 5-10 μg/kg subcutaneously every day
Study: NCT05052619

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Preventive use of advanced antibiotics
Description: Treat patients in this group with advanced preventive usage of antibiocs: Sulperazon 3g q8h, in postoperative days 1-5.
Study: NCT06148025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin Oral Capsule
Description: 500mg every 6 hours for 3 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin Oral Capsule
Description: 500mg every 6 hours for 3 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neomycin Oral Product
Description: 1000mg every 6 hours for 3 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neomycin Oral Product
Description: 1000mg every 6 hours for 3 days
Study: NCT06366321

Intervention type: OTHER
Group type: OTHER
Intervention: relining technique
Description: construction of complete denture by flasking and casting the relining impression

Intervention type: OTHER
Group type: OTHER
Intervention: CAD/CAM milling technique
Description: construction of complete denture by milling of the scanned relining impression
Study: NCT05019300

Intervention type: BIOLOGICAL
Intervention: Exposure: COVID-19 severity
Description: COVID-19 severity between 4 to 7 points according the seven-category scale of clinical status reported by Huang et al. (2021) and severe to critical symptomatic levels on spectrum of disease reported by Wu and McGoogan (2020).
Study: NCT05624398

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vivity IOL
Description: Cataract surgery with implantation of the Vivity IOL along with concurrent implantation of the Hydrus Microstent
Study: NCT05704504

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group-based exercise intervention with EMA and personalized telephone support (SUP)
Description: Participants in the SUP group will receive a 6-week group-based exercise intervention with EMA and personalized telephone support. The intervention content includes three 120-minute group-based exercise training sessions delivered by a physical trainer and three 15-minute personalized telephone sessions delivered by research personnel. The first group exercise session will include (1) assessments of current physical fitness, (2) psychoeducation of depression, (3) education on the benefits of exercise on mental health, (4) demonstration and group low-intensity exercise training, and (5) smart goal setting. A booklet that summarizes the session content will be provided to participants. The second and third group exercise sessions will include (1) reviewing exercise goals and EMA data, (2) problem-solving barriers to exercise, (3) group discussion on exercise experience, (4) demonstration and group moderate-intensity exercise training, and (5) smart goal setting.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Group-based exercise intervention (EXE)
Description: Participants in the EXE group will receive a 6-week group-based exercise intervention. The intervention content includes three 120-minute group-based exercise training sessions delivered by a physical trainer at the Chinese University of Hong Kong. The first group exercise session will include (1) assessments of current physical fitness, (2) psychoeducation of depression, (3) education on the benefits of exercise on mental health, (4) demonstration and group low-intensity exercise training, and (5) smart goal setting. A booklet that summarizes the session content will be provided to participants. The second and the third group exercise sessions will include (1) reviewing exercise goals, (2) problem-solving barriers to exercise, (3) group discussion on exercise experience, (4) demonstration and group moderate-intensity exercise training, and (5) smart goal setting.
Study: NCT04741074

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution
Description: Dose will be started at 0.25 mg per week. Dose escalation will occur every 4 weeks to mitigate risk of gastrointestinal side effects to a maximum dose of 1.0 mg per week.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 1.5 ml, prefilled pen-injector for subcutaneous injection solution
Description: Matched placebo solution for injection will be provided by Novo Nordisk in a 1.5 ml pre-filled pen-injector for subcutaneous injection with the same instructions on dose escalation.
Study: NCT06148025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neomycin Oral Product
Description: 1000mg every 6 hours for 3 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neomycin Oral Product
Description: 1000mg every 6 hours for 3 days
Study: NCT06338462

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Chatbot
Description: The chatbot is a WhatsApp-based, artificial-intelligence powered customer service agent adapted for TB outreach. The objective of the Chatbot is to facilitate information gathering, education, and support throughout TB contact evaluation, ensuring accessible assistance on-demand during and after contact tracing procedures. It operates in a secure data environment that includes end-to-end encryption and has been reviewed and approved by the data protection team within the information technology unit at the Cali Secretariat of Public Health (SoPH) for the study purposes.
Study: NCT05052619

Intervention type: OTHER
Group type: OTHER
Intervention: Routine
Description: Treat patients in this group with routine preventive usage of antibiocs: Cefmetazole 1g q12h, in postoperative days 1-3.
Study: NCT05703594

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: performance based balance test
Description: Performance based balance test; 360° Turn Test, Alternative Step Test, Pen Pickup Test,5 Repetitive Stand Up and Sit Test, 10 Meter Walk Test Lower extremity strengthening exercises; Quadriceps femoris strengthening exercise Hamstring strengthening exercise Gluteus medius muscle strengthening exercise Strengthening exercise for hip adductor muscles Balance exercises; Standing tandem walk Standing side walks Standing cross walks Standing back walking
Study: NCT04782947

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Exoskeletal assisted walking
Description: Exoskeletal assisted walking includes the use of robotic suit to train participant to walk with different level of assistance.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Exoskeletal assisted walking
Description: Exoskeletal assisted walking includes the use of robotic suit to train participant to walk with different level of assistance.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Epidural Stimulation
Description: lumbo-sacral epidural simulation at the beginning of the study.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resistance Training
Description: Using two forms of resistance training to increase muscle size. The first form includes seated leg extension exercise for 12 weeks followed by a second form that includes sit-to-stand exercise using participant's body weight.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: delayed-ES
Description: lumbo-sacral epidural simulation starting 6 months after the beginning of the study.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: no-Resistance training
Description: The participants will perform 24 weeks of passive movement or passive stretching from seated position.
Study: NCT05878340

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Miffy
Description: A method to stimulate children to try different fruits and vegetables using reward and role modelling

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Reward
Description: Reference method to stimulate children to try fruits and vegetables using reward alone
Study: NCT05475119

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous Positive Airway Pressure (CPAP)
Description: Continuous Positive Airway Pressure (CPAP) is a form of positive airway pressure ventilation in which a constant level of pressure greater than atmospheric pressure is continuously applied to the upper respiratory tract of an individual.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Flow Nasal Cannula (HFNC)
Description: High Flow Nasal Cannula (HFNC) is an oxygen supply system capable of delivering up to 100% humidified and heated oxygen at a flow rate of up to 60 liters per minute
Study: NCT05007912

Intervention type: PROCEDURE
Intervention: Esophagojejunostomy type
Description: Use of either circular or linear stapler

Intervention type: PROCEDURE
Intervention: Esophagojejunostomy type
Description: Use of either circular or linear stapler
Study: NCT06232551

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EHR (electronic health record) alert
Description: Pop-up alert that informs the discharging clinician that the patient meets criteria to be considered for extended duration thromboprophylaxis

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No EHR (electronic health record) alert
Description: During the baseline phase while risk is assessed and stored, no alerting occurs
Study: NCT06338462

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Oral testing
Description: Oral testing involves collection of a saliva sample or use of a nylon swab to collect material from the tongue and oral mucosa that is then tested with a molecular test for Mycobacterium tuberculosis
Study: NCT04841005

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Square-Step Exercise Training
Description: The Square-Step Exercise is instructed to walk according to the step pattern shown on a 100 \* 250 cm mat, divided into 40 squares of 25 cm each. It includes forward, backward, lateral and diagonal steps, and step patterns are progressively made more complex. Each pattern consists of two to 16 steps; Individuals are asked to repeat the step pattern until they reach the end of the mat. Each step pattern is repeated 4-10 times to ensure that individuals can complete the pattern. The individuals included in the study will exercise in easy-difficulty patterns for the first 2 weeks, medium-difficulty patterns in the 3rd and 4th weeks, medium and advanced patterns in the 5th and 6th weeks, and advanced patterns in the 7th and 8th weeks. The square-step exercise group will perform 15 minutes of warm-up exercise, 30 minutes of progressive square-step exercise, and 10 minutes of cool-down exercise accompanied by a physiotherapist, 3 days a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strengthening Exercise Training
Description: Thera-Band brand elastic bands will be used to apply resistance in strengthening training. To determine the intensity of the exercise, the perceived difficulty level after 15 repetitions with the elastic band will be evaluated with the Borg scale. If the perceived difficulty level is at the level of 12-14 (slightly difficult), it will be considered as the starting difficulty level.In the strengthening exercise group will perform, shoulder abduction, shoulder press after elbow flexion, horizontal abduction, punching with an elastic band, triceps strengthening, external rotation of the shoulder, hip abduction with external rotation and sit-to-stand exercises for 8 weeks, 3 days / week , 3 sets / sessions, 8-12 repetitions. For each exercise, it will be applied as 8 repetitions in the initial workload. In the next exercise sessions, the number of repetitions will be increased until the patient can comfortably perform 12 repetitions with the same load.
Study: NCT06119594

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Body Comp Pro connected scale (Withings manufacturer)
Description: Patients in the intervention group will use the connected scale at a minimum frequency of once a week from receipt of the scale and throughout their participation in the research (6 months)
Study: NCT05976711

Intervention type: DEVICE
Intervention: Magnetic resonance imaging (with PROUD software)
Description: Philips Ingenia 3.0T MR system with in-house developed PROUD software

Intervention type: DEVICE
Intervention: Magnetic resonance imaging (with PROUD software)
Description: Philips Ingenia 3.0T MR system with in-house developed PROUD software

Intervention type: DEVICE
Intervention: Magnetic resonance imaging (with PROUD software)
Description: Philips Ingenia 3.0T MR system with in-house developed PROUD software
Study: NCT05547828

Intervention type: DRUG
Group type: OTHER
Intervention: Tislelizumab combined with chemoradiotherapy
Description: Tislelizumab: According to the instructions of tislelizumab, 200 mg intravenously on the first day of each cycle, 21 days as a cycle.~Nab-paclitaxel: white purple: 100mg/m2 intravenous infusion on d1.8.15 (during chemotherapy) 100mg/m2 intravenous infusion q3w ╳ 3 cycles (during consolidation therapy) Radiotherapy: 40Gy/20f, 5 times/w, (esophageal primary tumor and metastatic lymph nodes)
Study: NCT06752096

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cerebral angiography, arterial embolization, thrombectomy
Description: This intervention will be conducted using robotic navigation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cerebral angiogram using robotic device
Description: Diagnostic cerebral angiogram will be performed using a robot to navigate guidewires and catheters to target vessels.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Meningioma embolization using robotic device.
Description: Meningioma tumors will be embolized using a robot to navigate catheters and wires to the target vessels to the tumor.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical thrombectomy for stroke using a robotic device.
Description: Mechanical thrombectomy procedure will use a robot to navigate catheters, guidewires, and thrombectomy devices to the target vessel.
Study: NCT06756347

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Patients receiving landmark-based brachial plexus blocks
Description: The operator will visualize anatomical structures in real time, identify the brachial plexus (supraclavicular approach), and guide the needle to the injection site under direct ultrasound visualization

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Landmark-Based Brachial Plexus Block
Description: The operator will identify anatomical landmarks (e.g., interscalene groove, supraclavicular fossa) using palpation and surface anatomy. The needle will be inserted based on these landmarks, with no direct visualization of internal structures.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: injected in both group as local anesthetic agent ( at a standardized concentration and volume) to ensure comparability.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: injected in both group as local anesthetic agent ( at a standardized concentration and volume) to ensure comparability.
Study: NCT04276155

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: non-systematic prescription of anticoagulant therapy
Description: the prescription of anticoagulant is managed by an implantable device follow up
Study: NCT06217419

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radio Frequency IDentification (RFID) device
Description: RFID devices monitor breathing patterns by means of temperature measurements of the respiratory airflow. The temperature gradient of the air flow in and out of the airways can be correlated to the flow-based respiratory patterns. Accordingly, a temperature-based breath monitoring can be achieved by means of on-skin RFID sensors attached below the nose. Finally, a bilateral measurement of nostrils respiratory flow can provide more information since nasal cavities do not behave in the same way during a respiratory cycle.~In this project we will evaluate the possibility to perform domestic breath flow analysis by exploiting thin, lightweight and battery-less sensing plasters directly attached under the nose. The system includes a proper external reader interrogating the face sensors that is capable to directly communicate with smartphone/pc/tablet/cloud environment.
Study: NCT05618093

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-invasive hemodynamic measurements
Description: A patient profile will be set up in the Edwards EV1000 clinical platform by inputting the patient's demographic information. One or two Edwards ClearSight finger cuffs will be placed on the index, middle, and/or ring finger on one hand of the patient. A pressure controller will be secured by a forearm strap where the finger cuffs will be connected to the pressure controller. The pressure controller will be connected to the Edwards EV1000 clinical platform monitor. A heart reference sensor (HRS) will be connected to the pressure controller, a finger cuff, and to the patient at heart level. The Edwards EV1000 clinical platform will calibrate the finger probes, then record measurements for 10-30 seconds. If two finger probes are available, measurements will alternate between fingers.
Study: NCT05154760

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor muscle training, diaphragmatic breathing exercise, core exercises
Description: An exercise program consisting of pelvic floor muscle training, diaphragmatic breathing exercise and core exercises will be applied to the patients.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor muscle training, diaphragmatic breathing exercise, core exercises
Description: An exercise program consisting of pelvic floor muscle training, diaphragmatic breathing exercise and core exercises will be applied to the patients.
Study: NCT06088160

Intervention type: PROCEDURE
Intervention: Total Hip Arthroplasty
Description: Total hip arthroplasty is a common surgical procedure performed in people with advanced hip osteoarthritis

Intervention type: PROCEDURE
Intervention: Total Hip Arthroplasty
Description: Total hip arthroplasty is a common surgical procedure performed in people with advanced hip osteoarthritis
Study: NCT05972252

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cerebrovascular Interventional Procedural Control System
Description: The Cerebrovascular Interventional Procedural Control System is intended for use in the remote delivery and manipulation of guidewires and rapid deliver stent catheters, and remote manipulation of guide catheters during cerebrovascular intervention procedures.