TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05271006

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The mHealth platform to be used by the exercise group is Down Dog, which has a suite of apps for yoga, HIIT, barre, and running workouts. Down Dog has agreed to provide free memberships for one year to all participants in the study. To ensure participant de-identification on the Down Dog platform, each participant will receive a Participant ID which will be pre-registered by the study coordinator on the Down Dog platform. Randomized participants will be provided instructions for downloading the apps onto their phone or a link to the website to be used on their computer. Following randomization, participants in the exercise group will be asked to engage in physical activity (using any if the Down Dog apps), 4 days a week for 20 minutes a day for 12 weeks.
Study: NCT06154603

Intervention type: PROCEDURE
Intervention: Surgical treatment type
Description: This observational design will study the clinical outcome for each type of upper gastrointestinal perforation in relation to surgical or non-surgery treatment and in relation to treatment centre.

Intervention type: PROCEDURE
Intervention: Surgical treatment type
Description: This observational design will study the clinical outcome for each type of upper gastrointestinal perforation in relation to surgical or non-surgery treatment and in relation to treatment centre.

Intervention type: PROCEDURE
Intervention: Surgical treatment type
Description: This observational design will study the clinical outcome for each type of upper gastrointestinal perforation in relation to surgical or non-surgery treatment and in relation to treatment centre.
Study: NCT05452031

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care2Sleep
Description: A multicomponent behavioral sleep program, consisting of sleep hygiene, stimulus control, sleep compression, pleasurable activity, daily walking, and light exposure.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Care2Sleep
Description: A multicomponent behavioral sleep program, consisting of sleep hygiene, stimulus control, sleep compression, pleasurable activity, daily walking, and light exposure.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Sleep Education
Description: This group will receive information about sleep, aging, and dementia, but without specific or individualized recommendations
Study: NCT05620771

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab and Bevacizumab
Description: Patients will receive atezolizumab + Bevacizumab for 21 days after standard of care therapy is complete.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Y90 + TKI
Description: Patients will receive TKI for 21 days after standard of care therapy is complete.
Study: NCT04914078

Intervention type: DRUG
Intervention: Mepolizumab 100 MG
Description: The patients will treated with subcutaneous Mepolizumab at 100 mg every 30 days. Patients will be recruited among those eligible to Mepolizumab treatment according to the Italian Medicine Agency (AIFA; Agenzia Italiana del Farmaco) guidelines who will accept to participate to the study. In particular inclusion criteria will be: severe (Step 4 and 5 GINA) asthma with at least blood eosinophilic count above 300 cells/mcl at least once in the previous year and ≥150 cells/mcl in the absence of systemic corticosteroid treatment before biological treatment initiation. In addition, one of the following conditions will be required: 1) ≥2 exacerbations in the previous year despite appropriate inhaled treatments or 2) the need for systemic corticosteroids on top of inhaled treatment for at least 6 months in the previous year.
Study: NCT05071560

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Combined exercise training
Description: Before the intervention, these women will undergo an evaluation of cardiorespiratory fitness, functional fitness, psychological status and a physiatry assessment. A consent form is signed before the start.~The physical exercise intervention was planned based on the recommendations of the American College of Sports Medicine for cancer survivors (ACSM 2019), with two supervised combined training sessions (mobility, aerobic training, strength and flexibility training) planned, and one unsupervised aerobic training session per week, interspersed with at least one rest day in between, for 8 weeks. The intensity will be individualized and defined based on the initial assessment. The structure of the training plan was based on the FITT-VP principles (frequency, intensity, time, type, volume and progression) recommended by the ACSM (2019).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined exercise training
Description: Before the intervention, these women will undergo an evaluation of cardiorespiratory fitness, functional fitness, psychological status and a physiatry assessment. A consent form is signed before the start.~The physical exercise intervention was planned based on the recommendations of the American College of Sports Medicine for cancer survivors (ACSM 2019), with two supervised combined training sessions (mobility, aerobic training, strength and flexibility training) planned, and one unsupervised aerobic training session per week, interspersed with at least one rest day in between, for 8 weeks. The intensity will be individualized and defined based on the initial assessment. The structure of the training plan was based on the FITT-VP principles (frequency, intensity, time, type, volume and progression) recommended by the ACSM (2019).
Study: NCT05539105

Intervention type: PROCEDURE
Intervention: Double tract reconstruction
Description: Double tract reconstruction would be applied after radical proximal gastrectomy.

Intervention type: PROCEDURE
Intervention: Gastric conduit reconstruction
Description: Gastric conduit reconstructionn would be applied after radical proximal gastrectomy.

Intervention type: PROCEDURE
Intervention: Other reconstructions
Description: Other reconstructions except for double tract and gastric conduit reconstructions would be applied after radical proximal gastrectomy.
Study: NCT05606224

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: internet-based mindfulness intervention for emotional distress
Description: The internet-based self-help version of the Mindfulness Intervention for Emotional Distress (iMIED) program integrates rationales and practices from the UP and MBIs. Formal mindfulness exercises (e.g., body scan, mindful breathing, and mindful stretching) and informal mindfulness practices (e.g., mindful tooth-brushing) were retrieved from MBIs. In addition, iMIED selected several important tasks from the UP, like practicing tolerating uncomfortable feelings by interoceptive exposure practices (e.g., rapid breathing), identifying avoidant behaviors and emotion-driven behaviors and reducing them step by step, identifying common maladaptive automatic thoughts (e.g., overestimating probability and catastrophizing), and using the above strategies in daily life by completing challenging tasks.
Study: NCT05006521

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler
Study: NCT04457453

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Macintosh in sniffing position
Description: Macintosh direct intubation in sniffing position

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Macintosh in Trendelenburg position and Sellick position
Description: Macintosh direct laryngoscopic intubation in Trendelenburg position and Sellick position

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AceScope in Trendelenburg position and Sellick position
Description: AceScope videolaryngoscopic intubation in Trendelenburg position and Sellick position
Study: NCT05322902

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: remimazolam group
Description: Remimazolam 6 mg/kg/hr is administered as an intravenous infusion until the patient loses consciousness. Anesthesia is maintained at 1 mg/kg/hr of remimazolam. After confirming that the eyelash reflex disappears, rocuronium 0.8 mg/kg is administered, and SGA insertion is performed. During maintenance of general anesthesia, the concentration of remifentanil is continuously adjusted so that the ANI is above 50.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: propofol group
Description: Propofol intravenous infusion is initiated by the application of a target concentration infusion (TCI) pump to cause the patient to lose consciousness. After confirming that the eyelash reflex disappears, rocuronium 0.8 mg/kg is administered, and SGA insertion is performed. During maintenance of general anesthesia, the concentration of remifentanil is continuously adjusted so that the ANI is above 50.
Study: NCT05006521

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler
Study: NCT00320567

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: norgestimate/ethinyl estradiol
Study: NCT06327711

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control: CHO Blend
Description: 2 servings as a snack or between meals morning and evening

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental: CHO Blend plus AN100
Description: 2 servings as a snack or between meals morning and evening
Study: NCT06364878

Intervention type: DIAGNOSTIC_TEST
Intervention: In vivo confocal microscopy
Description: The patients cornea will be examined non-invasively by IVCM

Intervention type: DIAGNOSTIC_TEST
Intervention: In vivo confocal microscopy
Description: The patients cornea will be examined non-invasively by IVCM

Intervention type: DIAGNOSTIC_TEST
Intervention: Tear film sampling
Description: Patients tear film will be collected and stored at -80 degrees for analysis
Study: NCT05671250

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PRP gel and SOC-treatment
Description: Platelet-lysate loaded sustained release thermo-gelling formulation

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: EPO/ISDN/UFH cryogel dressing
Description: Erythropoietin/Isosorbide dinitrate loaded cryogel scaffold

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Sharp debridement, saline washing and regular saline dressing
Study: NCT05472792

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Accelerated Partial Breast Irradiation (APBI)
Description: Radiation treatment delivered to the lumpectomy cavity.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene
Description: Adjuvant endocrine therapy (tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene) for duration of 5 years, as tolerated by the patient.
Study: NCT05318508

Intervention type: OTHER
Intervention: Measurements of sagittal spinopelvic parameters
Description: Sagittal spinopelvic parameters will be measured from lateral cervicothoracolumbar radiographs of patients with lower extremity amputation.

Intervention type: OTHER
Intervention: Measurements of sagittal spinopelvic parameters
Description: Sagittal spinopelvic parameters will be measured from lateral cervicothoracolumbar radiographs of patients with lower extremity amputation.
Study: NCT06364878

Intervention type: DIAGNOSTIC_TEST
Intervention: Tear film sampling
Description: Patients tear film will be collected and stored at -80 degrees for analysis
Study: NCT05710575

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: probiotic
Description: Probiotic or placebo administration will be started from the first feed of the infants. Infants in the probiotic group will receive five drops of oil-based suspension containing 1×108 colony-forming units of L reuteri (DSM 17938 Biogaia AB, Stockholm, Sweden) once a day, until death or discharge from the hospital. For infants on oral feeds, after suctioning oral secretions, five drops will be placed in the posterior oropharynx of the infants. For infants without per oral feeds, five drops will be administered through a gastric tube followed by a flash of 0.5 mL of sterile water. For the infants in the placebo group, five drops from an identical vial containing only oil base will be administered following the same protocol as the probiotic group.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: placebo
Description: Probiotic or placebo administration will be started from the first feed of the infants. Infants in the probiotic group will receive five drops of oil-based suspension containing 1×108 colony-forming units of L reuteri (DSM 17938 Biogaia AB, Stockholm, Sweden) once a day, until death or discharge from the hospital. For infants on oral feeds, after suctioning oral secretions, five drops will be placed in the posterior oropharynx of the infants. For infants without per oral feeds, five drops will be administered through a gastric tube followed by a flash of 0.5 mL of sterile water. For the infants in the placebo group, five drops from an identical vial containing only oil base will be administered following the same protocol as the probiotic group.
Study: NCT05238480

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: XC mouthguard
Description: Use of a Xtreme Conventional custom-made mouthguard while playing rugby

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: XC mouthguard
Description: Use of a Xtreme Conventional custom-made mouthguard while playing rugby

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: XP mouthguard
Description: Use of a Xtreme Pro custom-made mouthguard while playing rugby

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: XP mouthguard
Description: Use of a Xtreme Pro custom-made mouthguard while playing rugby
Study: NCT05815914

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: app
Description: The app will include a nutritional education programme through the APP throughout the study. At 2, 4, 6 and 8 months data will be collected through a telematics questionnaire

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control group
Description: Routine nutritional and dietary recommendations will be given.
Study: NCT04974450

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Trigona honey
Description: composition : vitamin C 0.15%, Protein 1.32%, lipid 0.23%, carbohydrate 64.12%, beta carotene 10.61 ppm, Calcium 273,23, magnesium 338.94, zinc 12.49 ppm, and acidity 5.76. Total polyphenol 133.52 ppm, total flavonoid 159.62 ppm. This liquid has a sour profile

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: Artificial honey with fructose, Glucose, pure honey (2,271%), citric acid, and lime extract (0,076%).
Study: NCT06370572

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PAINAD EHR Prompt
Description: Implementation of PAINAD EHR prompt in the ED workflow for PLWD presenting to the ED with hip pain
Study: NCT06334549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ephedrine-P
Description: after induction of anesthesia, use total intravenous anesthesia maintained with propofol
Study: NCT05006521

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: KN-002
Description: KN-002 dry powder inhaler
Study: NCT06101524

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Free gingival unit, free gingival greft
Description: The free gingival graft and the free gingival unit taken from the upper jaw palatal mucosa were sutured to the lower jaw anterior region.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Free gingival unit, free gingival greft
Description: The free gingival graft and the free gingival unit taken from the upper jaw palatal mucosa were sutured to the lower jaw anterior region.
Study: NCT06334549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenylephrine-P
Description: after induction of anesthesia, use total intravenous anesthesia maintained with propofol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Norepinephrine-P
Description: after induction of anesthesia, use total intravenous anesthesia maintained with propofol

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ephedrine-S
Description: after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane
Study: NCT06616948

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Cycling Group
Description: engaged with a research staff member for 30 minutes of cycling

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: coaching calls
Description: individuals will receive a phone call every 14 days to discuss ongoing exercise maintenance efforts.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: No coaching calls
Description: Following completion of the 6-month cycling sessions, no maintenance calls will be placed.
Study: NCT03992950

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maneuvers for occluding esophagus
Description: Cricoid pressure: pressure on the cricoid ring Paratracheal pressure: pressure on the left paratracheal region below the cricoid level

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maneuvers for occluding esophagus
Description: Cricoid pressure: pressure on the cricoid ring Paratracheal pressure: pressure on the left paratracheal region below the cricoid level
Study: NCT04796584

Intervention type: OTHER
Intervention: Analysis of cell-mediated and antibody-mediated immunity to SARS-CoV-2 virus
Description: mRNA vaccination for SARS-CoV-2 is not provided by the study

Intervention type: OTHER
Intervention: Analysis of cell-mediated and antibody-mediated immunity to SARS-CoV-2 virus
Description: mRNA vaccination for SARS-CoV-2 is not provided by the study

Intervention type: OTHER
Intervention: Analysis of cell-mediated and antibody-mediated immunity to SARS-CoV-2 virus
Description: mRNA vaccination for SARS-CoV-2 is not provided by the study
Study: NCT06334549

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phenylephrine-S
Description: after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine-S
Description: after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane
Study: NCT04796584

Intervention type: OTHER
Intervention: Analysis of cell-mediated and antibody-mediated immunity to SARS-CoV-2 virus
Description: mRNA vaccination for SARS-CoV-2 is not provided by the study
Study: NCT05381480

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: In-home Preventive Health Visits by Advanced Practice Nurse
Description: Elements of Comprehensive Geriatric Assessment used as a preventive, health risk assessment, with recommendations tailored for health risks identified and offered to building tenants

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: On-site Evidence-based Physical Activity, Health and Wellness Classes
Description: Weekly calendar of health promotion and injury/illness prevention classes offered to building tenants.
Study: NCT04811690

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: front-of-package modification
Description: testing front-of-package changes to claims, imagery, disclosures, and added sugar warning labels on fruit-flavored drinks
Study: NCT05732649

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Auditory neurofeedback
Description: Network interaction measured with EEG at visual areas will be coupled with the intensity of a sound.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tactile neurofeedback
Description: Network interaction measured with EEG at visual areas will be coupled with the intensity of tactile stimulation (i.e., electrical or vibrotactile stimulators applied on both hands and feet).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Auditory and tactile neurofeedback
Description: Network interaction measured with EEG at visual areas will be coupled with the intensity of a sound and tactile stimulation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neurofeedback
Description: Participants train to decrease the intensity of a sensory stimulation (defined in Experiment 1) that is coupled with the network interaction at a specific brain region.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Neurofeedback
Description: Participants train to decrease the intensity of a sensory stimulation (defined in Experiment 1) that is coupled with the network interaction at a specific brain region.
Study: NCT05076058

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Tablet of silybum marianum, Pueraria lobate and salvia miltiorrhiza
Description: Brand names: BY-HEALTH；~Main contents (per 100g): silibinin 2g, salvianolic acid B 0.72g，Puerarin 0.68g

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet
Description: Brand names: BY-HEALTH；~Main contents : starch
Study: NCT06492070

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Undergo standard of care

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cilostazol
Description: Given PO

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryocompression Therapy
Description: Undergo cryocompression therapy

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryocompression Therapy
Description: Undergo cryocompression therapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given by infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given by infusion

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT05068362

Intervention type: DEVICE
Group type: OTHER
Intervention: Auricular reconstruction
Description: Medpor implant for treatment of microtia
Study: NCT05500378

Intervention type: OTHER
Group type: OTHER
Intervention: Head extension and rotation movement
Description: Active exercise of the head