TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05157334

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-invasive auricular electrical transcutaneous vagus nerve stimulation
Description: A NEMOS ® stimulator (Cerbomed, Erlangen, Germany) is used for transcutaneous auricular vagus nerve stimulation. This is a handheld battery driven stimulator which stimulates conca in the outer ear. It stimulates in a serie of small electrical impulses with a pulse width at 250 us and a frequency at 25 Hz for 30 minutes in a cycle for 30 seconds on and 30 seconds off to avoid habituation. It is previously indicated that a stimulation intensity at 0,5 mA, 1 mA or 1,5 mA does not cause a significant chance in HRV, thus 0,5 mA is used in this study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep breathing
Description: The participant is first verbally introduced to the breathing exercises, and then to the visually cue (animation), which the participant have to follow throughout the session.
Study: NCT06622486

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EGL-001
Description: IV administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EGL-001
Description: IV administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EGL-001
Description: IV administration
Study: NCT06678048

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arsenous Acid plus Chemotherapy
Description: Arsenous Acid , Eribulin, Gemcitabine, Utidelone, Vinorelbine
Study: NCT06314308

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CATCHES
Description: At the baseline visit (T0), informed consent will be obtained, and baseline questionnaires and measurements completed. A physical activity monitor will be provided. After discharge, Task Specific Training guided by Cognitive Behavioral Therapy with Exposure delivered over 7 one-hour sessions including two intake sessions by specialists and five follow up sessions delivered by CHWs individually at home over 3 months. After the final session at 12 weeks (about 3 months), participants will complete a study end visit (T1) which will include follow up questionnaires and measurements.
Study: NCT06262334

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Fade to Fitness Program
Description: The Fade to Fitness Program is a group-based and barbershop-based behavioral intervention to improve health-related quality of life among African American men. The program is unique because it is culturally targeted and individually tailored. The culturally targeted content was developed following barbershop-based focus groups. The Fade to Fitness Program targets four behaviors strongly linked to health-related quality of life among African American men - physical activity, healthy eating, stress management, and depression management. During the group-based portion of the program, Motivational Interviewing is used by the facilitator as a conversational approach to enhance participants\&#39; motivation and commitment towards positive behavior change. The goal is to foster intrinsic motivation among participants to engage in these behaviors. It is individually tailored by encouraging participants to identify personal values and linking them to health promoting behaviors.
Study: NCT05608369

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Cisplatin100 mg/m2 every 3 weeks or 40 mg/m2 weekly

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation therapy
Description: Radiation therapy (70 Gy) for total of 7 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vorinostat
Description: Pre-treatment; 300 mg every other day and ends with the dose closest to the last fraction of radiation (total of 8 weeks)
Study: NCT05863689

Intervention type: DIAGNOSTIC_TEST
Intervention: Spectralis SD-OCT
Description: Optical Coherence Tomography
Study: NCT05000697

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Patients will receive 5FU + Oxaliplatin during the consolidation chemotherapy after long course chemoradiation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5FU
Description: Patients will receive 5FU during the consolidation chemotherapy after long course chemoradiation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5FU
Description: Patients will receive 5FU during the consolidation chemotherapy after long course chemoradiation
Study: NCT06247683

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: trifocal intraocular lens
Description: cataract extraction and implantation of a posterior chamber trifocal intraocular lens
Study: NCT05847764

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48+Tislelizumab+carboplatin
Description: RC48+PD-1/PD-L1 inhibitor+chemo in treatment-naive patients harboring HER2 alterations

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48+Furmonertinib, 1L
Description: RC48+Furmonertinib in treatment-naive patients harboring EGFR mutations as well as HER2 alterations

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48+Furmonertinib, 2L+
Description: RC48+Furmonertinib in patients who failed at least one line of standard treatment and harboring HER2 alterations
Study: NCT03676556

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine
Description: Two sterile gauzes will be dampen with the content of the syringe (20ml lidocaine 0.5%) and apply on the wound. After 7-15minutes of waiting to the effect, the wound treatment will start.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline Solution
Description: Two sterile gauzes will be dampen with the content of the syringe (20ml saline serum) and apply on the wound. After 7-15minutes of waiting to the effect, the wound treatment will start.
Study: NCT06677619

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intrusion by reverse curve wire in cervical position of twin slot bracket
Description: intrusion of anterior teeth by putting reverse curve wire in incisal slot of twin slot bracket

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intrusion by reverse curve wire in cervical position of twin slot bracket
Description: intrusion of anterior teeth by putting reverse curve wire in incisal slot of twin slot bracket
Study: NCT06678009

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: the isokinetic training group with blood flow restriction
Description: The isokinetic training protocol for the knee flexor and extensor muscles consisted of 3 sets of 10 repetitions in 60°/sec and 3 sets of 30 repetitions in 180°/sec for 8 weeks, 2 times per week for 16 sessions.

Intervention type: DEVICE
Group type: OTHER
Intervention: the isokinetic training group without blood flow restriction
Description: The isokinetic training protocol for the knee flexor and extensor muscles consisted of 3 sets of 10 repetitions in 60°/sec and 3 sets of 30 repetitions in 180°/sec for 8 weeks, 2 times per week for 16 sessions.
Study: NCT04602741

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A4i Intervention
Description: 6 months of the provision of A4i on the individual's own device.
Study: NCT05263635

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music therapy
Description: Music therapy will include music intervention based on recommendations from literature such as slow, flowing rhythm, approximately 60-80 beats/minute and played by string instruments, played with a volume of approximately 45 decibel and will be reviewed by qualified music therapists.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care Enhanced Recovery After Surgery (ERAS)
Description: Patients will receive the standard of care treatment for surgery and post-operative pain management, following the Enhanced Recovery After Surgery (ERAS) protocol
Study: NCT06045637

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group included in a psychoeducational program based on the cognitive behavioral approach (experiment)
Description: The 9-session cognitive behavioral approach-based psychoeducation program will last 5 weeks. Sessions; It will be carried out in the form of acquaintance, recognition of trauma and its effects, emotion and thought behavior analysis, cognitive errors, automatic thoughts and alternative thought generation, cognitive emotion regulation strategies, coping with negative emotions, instilling hope and termination session.
Study: NCT05892575

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: improving quality of life, coping with urinary incontinence and kegel exercise training
Description: Face-to-face training will be given to the elderly in the experimental group for a total of 5 weeks, once a week day (60 minutes). In the 4th week, reminder messages will be started over the phone. The 4th week kegel exercise chart and nutrition list will be given. In the 5th week, kegel exercise dance will be watched. Sending reminder messages from the phone will continue for 3 months.
Study: NCT06154226

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pantoprazole
Description: Subjects will receive pantoprazole (40 mg iv q12H) for 2 days perioperatively (first dose after anesthesia induction and before surgical incision, second dose at chest closure, then followed by 2 doses daily (Q12hr dosing) on post operative day 1 (POD 1) for a total of 4 doses over 2 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Famotidine
Description: Subjects will receive famotidine (20 mg iv q12H) for 2 days perioperatively (first dose after anesthesia induction and before surgical incision, second dose at chest closure, then followed by 2 doses daily (Q12hr dosing) on POD 1 for a total of 4 doses over 2 days.
Study: NCT06518187

Intervention type: OTHER
Intervention: Assessing the impact of three different catheter advancement techniques on needle tip movement during intravenous insertion
Description: Each participant will perform 3 simulated IV catheter insertions using each of the specified techniques. Participants will use the instrumented 16ga IV catheter to insert into the peripheral vascular access simulator. Needle tip movement (from intent of catheter advancement to 5mm of advancement off the needle) will be measured with 0.2mm accuracy using the electromagnetic tracking technology of the simulator. Data collected will include needle movement after simulated vein punction and during initial catheter advancement off the needle (in mm) which will be recorded within the simulation program and output as a de-identified Excel file
Study: NCT06536751

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Photobiomodulation
Description: LED photobiomodulation therapy, once a week, for 08 consecutive weeks in the same day of the institution's standard physiotherapy session that the patient already uses regularly (not linked to the study). PBM will be transcutaneously, punctual application of the LED in the medial and lateral gastrocnemius muscles of the right lower limb, in contact mode, 3J/cm2, with a 850nm wavelenght.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Institution's Standard Physiotherapy
Description: Physiotherapy treatment on the University, occur 2 therapeutic days per week, for 08 consecutive weeks (one of them in the same day of the PBM session). It consists of the use of motor physiotherapy, posture guidelines, stretching, positioning, joint range gain, ergonomics, sensory stimulation and proprioception, motor strengthening, tonus adjustment, functional training of upper and lower limbs, guidelines for the use of orthoses, stands, parapodium, parallel bars or wheelchair when needed. These are 45-minute sessions conducted by a physiotherapist.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Institution's Standard Physiotherapy
Description: Physiotherapy treatment on the University, occur 2 therapeutic days per week, for 08 consecutive weeks (one of them in the same day of the PBM session). It consists of the use of motor physiotherapy, posture guidelines, stretching, positioning, joint range gain, ergonomics, sensory stimulation and proprioception, motor strengthening, tonus adjustment, functional training of upper and lower limbs, guidelines for the use of orthoses, stands, parapodium, parallel bars or wheelchair when needed. These are 45-minute sessions conducted by a physiotherapist.

Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Photobiomodulation Placebo
Description: The same procedures of PBM group but device will be turned off
Study: NCT05119855

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 9vHPV Vaccine
Description: 9-valent human papillomavirus (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) administered as a 0.5-mL intramuscular (IM) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 9vHPV Vaccine
Description: 9-valent human papillomavirus (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) administered as a 0.5-mL intramuscular (IM) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273 Vaccine
Description: mRNA-1273 50 mcg dose administered as a 0.25-mL IM injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273 Vaccine
Description: mRNA-1273 50 mcg dose administered as a 0.25-mL IM injection
Study: NCT04857398

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: insulin icodec
Description: Participants will get insulin icodec once a week for 6 weeks. The medicine will be injected under the skin.~The study will last for 15 to 22 weeks.
Study: NCT05263635

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Enhanced Recovery After Surgery (ERAS)
Description: Patients will receive the standard of care treatment for surgery and post-operative pain management, following the Enhanced Recovery After Surgery (ERAS) protocol
Study: NCT06043804

Intervention type: OTHER
Intervention: Doppler ultrasound measurement of changes in uterine artery blood flow
Description: Doppler ultrasound measurement of changes in uterine artery blood flow

Intervention type: OTHER
Intervention: Doppler ultrasound measurement of changes in uterine artery blood flow
Description: Doppler ultrasound measurement of changes in uterine artery blood flow
Study: NCT05674565

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium sulfate loading with maintenance dose
Description: 4 gm MgSo4 loading over 20 minutes followed by 1 gm per hour maintenance till delivery

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium sulfate loading dose only
Description: 4 gm MgSo4 loading over 20 minutes within one hour before delivery
Study: NCT04746976

Intervention type: DRUG
Intervention: Diroximel Fumarate
Description: As described in the arm.
Study: NCT05071573

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Optimised electronic patient records
Description: Viral load champions trained in the monitoring of patient on antiretroviral therapy to aid prompt identification of virological failure and institution of appropriate clinical management
Study: NCT05421845

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mobile-based combining with hospital-based lifestyle interventions
Description: The same as that stated in arm descriptions.
Study: NCT06009783

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ChatGPT Language Model
Description: ChatGPT Language Model - ability to converse with the model and ask questions regarding vasectomies
Study: NCT05580679

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abdominal massage
Description: Application time of the massage: 30 minutes after meals, twice a day, at 10:00 in the morning and at 16:00 in the evening.~Application time of the massage: 15 minutes each Materials needed: Gloves, Liquid Vaseline, Paper Towel Massage methods used: Efflorage, Petrissage, Vibration
Study: NCT04981392

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Primary care text message outreach to unvaccinated patients and resources to support PCPs
Description: Patients: Eligible patients will receive a series of text messages from their PCP or primary care clinic recommending a study website as a trusted source of information about the COVID-19 vaccines and information on how and where to schedule a vaccination.~Providers: PCPs will receive resources to support their conversations with patients about the COVID-19 vaccines (factsheets, prescription pads, electronic smartphrase).
Study: NCT06135415

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirbanibulin
Description: Participants will apply tirbanibulin ointment topically on the face or balding scalp with AK.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle ointment
Description: Participants will apply vehicle ointment topically on the face or balding scalp with AK.
Study: NCT05245253

Intervention type: RADIATION
Intervention: Positron Emission tomography
Description: Patients will be tested with PET-examination at 3 weeks, 3 months and 1 year after the trauma
Study: NCT04856891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK002
Description: Lirentelimab (AK002) is a humanized non-fucosylated immunoglobulin G1(IgG1) monoclonal antibody directed against Siglec-8.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05082831

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: microfracture surgery + HST003
Description: This is an Intervention Model where all patients who are identified/confirmed candidates for microfracture surgery will be enrolled to receive the microfracture surgery (standard of care). Ten (10) patients will be randomized to receive the study intervention (HST003). HST003 will be injected into the microfracture defects (interstices) and fill the remainder of the defect to the cartilage margin following surgery. The primary purpose of the study is to compare the two groups: microfracture surgery + HST003 as compared to the microfracture surgery only group.
Study: NCT05497635

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 Injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 Injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSA-1002 Injection
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intravenous injection
Study: NCT04723758

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GI Genius-assisted diagnostic colonoscopy
Description: Participants will undergo diagnostic colonoscopy, which will be identical to the normal standard of care at the unit where they are undergoing their procedure, except that GI Genius will be turned on during the procedure.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Diagnostic Colonoscopy
Description: Diagnostic colonoscopy will be performed as per the standard of care for the unit where the patient is having their procedure.
Study: NCT05751642

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALXN1920
Description: Participants will receive a single dose of ALXN1920 by Subcutaneous (SC) injection.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALXN1920
Description: Participants will receive a single dose of ALXN1920 by Subcutaneous (SC) injection.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive a single dose of Placebo by SC injection, SC infusion or IV infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALXN1920
Description: Participants will receive a single dose of ALXN1920 by SC infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALXN1920
Description: Participants will receive a single dose of ALXN1920 by SC infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALXN1920
Description: Participants will receive a single dose of ALXN1920 by SC infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALXN1920
Description: Participants will receive a single dose of ALXN1920 by Intravenous (IV) infusion.
Study: NCT05360368

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX07
Description: A Recombinant Humanized Anti-EGFR Monoclonal Antibody, HLX07 will be administered as a single intravenous (IV) infusion on Day 1 in each 3-week cycle
Study: NCT05874648

Intervention type: DEVICE
Intervention: Multi-cancer early detection test
Description: Blood collection and multi-cancer early detection test

Intervention type: DEVICE
Intervention: Multi-cancer early detection test
Description: Blood collection and multi-cancer early detection test
Study: NCT04896255

Intervention type: DRUG
Intervention: peginterferon alpha based regimen
Description: peginterferon alpha based regimen or nucleos(t)ide alone are decided by patients' doctors according to their conditions, instead of extra interventions brought by the study

Intervention type: DRUG
Intervention: nucleos(t)ide
Description: peginterferon alpha based regimen or nucleos(t)ide alone are decided by patients' doctors according to their conditions, instead of extra interventions brought by the study
Study: NCT04497584

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afatinib + Prednisone
Description: Afatinib (40mg) will be taken by mouth daily starting on Cycle 1, Day -7. Prednisone (40mg) will be taken by mouth daily starting on Cycle 1, Day 1.
Study: NCT06193330

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: antibiotic-coated plate
Description: A plate for fixing long bone fractures is coated with antibiotics cement prepared in theatre

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: external fixator
Description: external fixators are applied to participants with severe long bone fractures
Study: NCT04697784

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TREO Abdominal Stent-Graft System
Description: The TREO Abdominal Stent-Graft System is intended for the treatment of infrarenal abdominal aortic aneurysms with or without iliac involvement.
Study: NCT05543395

Intervention type: BEHAVIORAL
Intervention: Domestic Violence Questionnaire
Description: Domestic Violence Questionnaire

Intervention type: BEHAVIORAL
Intervention: Domestic Violence Questionnaire
Description: Domestic Violence Questionnaire
Study: NCT05483608

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vertical climbing ergometer exercise
Description: Exercise using the CLMBR, a vertical climbing exercise ergometer.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Recumbent cycling
Description: Exercise using a recumbent cycle ergometer
Study: NCT05105152

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SC-DARIC33
Description: Infusion with SC-DARIC33 followed by intermittent oral rapamycin administration
Study: NCT06256003

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: UC-A
Description: Mobile app digital therapy

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: UC-N
Description: Mobile app digital therapy