TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05944848

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 1 mg CL-197 capsules
Description: Single oral dose of 1 mg CL-197 capsules or CL-197 placebo administered following ≥10 hour fast

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10 mg CL-197 capsules or CL-197 placebo
Description: Single oral dose of 10 mg CL-197 capsules or CL-197 placebo administered following ≥10 hour fast

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 30 mg CL-197 capsules or CL-197 placebo
Description: Single oral dose of 30 mg CL-197 capsules or CL-197 placebo administered following ≥10 hour fast

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 60 mg CL-197 capsules or CL-197 placebo
Description: Single oral dose of 60 mg CL-197 capsules or CL-197 placebo administered following ≥10 hour fast

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 100 mg CL-197 capsules or CL-197 placebo
Description: Single oral dose of 100 mg CL-197 capsules or CL-197 placebo administered following ≥10 hour fast
Study: NCT04927299

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan/Chlorthalidone in fixed dose
Description: 1 tablet, once a day of 50 mg/12.5 or 100 mg/ 25 mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Losartan + hydrochlorothiazide in fixed dose
Description: 1 tablet, once a day of 50 mg/12.5 or 100 mg/ 25 mg
Study: NCT04564183

Intervention type: OTHER
Intervention: Sample collection
Description: Blood, Urine, Nail, Hair, Saliva, optional Stool

Intervention type: OTHER
Intervention: Questionnaires
Description: SF-36, Food Frequency, Pulmonary Fibrosis Study questionnaire, COVID questionnaire

Intervention type: RADIATION
Intervention: High resolution CT scan of the chest
Description: Upon enrollment, all participants will undergo single prone volumetric thoracic chest CT scan. This will be performed at full inspiration using a 64-slice CT scanner.

Intervention type: DIAGNOSTIC_TEST
Intervention: Pulmonary Function Test
Description: All recruited participants will undergo a pre-bronchodilator spirometry test and a lung diffusion capacity test, both in accordance with ATS guidelines. Exercise capacity (maximum physical exertion) will be assessed by performing a 6-minute walk test, also according to ATS guidelines.
Study: NCT06646731

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: cryoneurolysis
Description: Peripheral nerve cryoneurolysis of the foot

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham cryoneurolysis
Description: a sham probe will be placed percutaneously proximal to target nerves. No cryoneurolysis will be given.
Study: NCT06651515

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic Pancreatic Endocrine Cell Clusters
Description: Allogeneic Pancreatic Endocrine Cell Clusters
Study: NCT06666400

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LHMoms Intervention
Description: The LHM arm (N=300) will receive a CBT+ Cardiovascular Health (CVH) Intervention to reduce CV risk. LHM employs a (CBT) + cardiovascular health (CVH) intervention delivered by doulas and integrating a healthy lifestyle intervention to reduce CV risk. The LHM intervention integrates the following key elements: (1) doula-led emergency detection in the first 7 days post-discharge; (2) home BP monitoring (HBPM); and (3) 12-sessions of the doula-delivered intervention to prevent PPD and reduce CV risk from 1 week to 6 months post-discharge, supported by (4) education through the Patient-Activated Learning System (PALS), a novel education platform used to engage low-literacy, racially marginalized individuals. LHM is based on the Thinking Healthy Programme (THP), an intervention originally designed to treat PPD in low and middle-income countries using community health workers.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No intervention
Description: Standard doula care and the same number of telephone or video-delivered sessions and will last the same amount of time on general postpartum health topics not related to CV health or depression. Attention control participants will not receive doula-initiated outreach during the first 7 days.
Study: NCT05305183

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Minodronate Tablets and Alendronate Sodium Tablets-matching placebo;Alendronate Sodium Tablets and Minodronate Tablets -matching placebo
Description: all subjects will receive Calcium Carbonate and Vitamin D3 Tablets as basic medication.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Minodronate Tablets and Alendronate Sodium Tablets-matching placebo;Alendronate Sodium Tablets and Minodronate Tablets -matching placebo
Description: all subjects will receive Calcium Carbonate and Vitamin D3 Tablets as basic medication.
Study: NCT05049889

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Terrestrial exercise
Description: At visit 1 (Day 0), an exercise test will be performed (maximal incremental test), followed by a 30-minute submaximal exercise at constant load.~During this exercise, continuous data collection will be performed:~* Continuous 12-lead electrocardiogram~* Continuous monitoring of blood pressure and ventilation.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Terrestrial exercise
Description: At visit 1 (Day 0), an exercise test will be performed (maximal incremental test), followed by a 30-minute submaximal exercise at constant load.~During this exercise, continuous data collection will be performed:~* Continuous 12-lead electrocardiogram~* Continuous monitoring of blood pressure and ventilation.
Study: NCT05533593

Intervention type: DRUG
Intervention: Aminoglycoside
Description: Inpatients using aminoglycoside

Intervention type: DRUG
Intervention: Aminoglycoside
Description: Inpatients using aminoglycoside
Study: NCT06295874

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Effect of aromatherapy massage on vital signs, pain, anxiety and comfort level
Description: The study applied a mixture of lavender, thyme and eucalyptus oil (5 drops of lavender oil, 4 drops of thyme oil, 3 drops of eucalyptus oil and 20 ml of almond oil in 20 ml) to patients who were monitored in intensive care on high-flow and oxygen, for three days. It was conducted as a randomized controlled single-blind study to evaluate the effects of aromatherapy massage applied twice a day for a total of 30 minutes on some physiological parameters, pain, anxiety and comfort levels.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Effect of aromatherapy massage on vital signs, pain, anxiety and comfort level
Description: The study applied a mixture of lavender, thyme and eucalyptus oil (5 drops of lavender oil, 4 drops of thyme oil, 3 drops of eucalyptus oil and 20 ml of almond oil in 20 ml) to patients who were monitored in intensive care on high-flow and oxygen, for three days. It was conducted as a randomized controlled single-blind study to evaluate the effects of aromatherapy massage applied twice a day for a total of 30 minutes on some physiological parameters, pain, anxiety and comfort levels.
Study: NCT05182060

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transition Intervention
Description: We will implement a bundle of care transition safety strategies with the assistance of home care coordinators at the study site and corresponding home health provider teams (nurses, rehabilitation therapists).~Home care coordinators will approach patients at the study site being referred for home health and provide resources to assist them with preparing for their transition home. These resources include a link to a video about home health services, a caregiver assessment, a care task role assignment sheet, and a shopping list. The study team will contact the older adult and caregiver by telephone within 48 hours of the home visit to confirm eligibility, explain the study, obtain consent for participation, and ask them to complete the the Hospital-to-Home Health Transition Quality Index (H3TQ) over the phone. Home health providers in the home will also complete the H3TQ.
Study: NCT06578221

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kegel Pelvic Floor Muscle Exercise Group
Description: After the surgery, the patients will be taken to the clinic room in a supine position and the researcher will perform the Kegel pelvic floor muscle exercises three times at the 1st, 4th and 7th hours within the first 8 hours after the patients are taken to the clinic room.
Study: NCT06578481

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercises
Description: Individuals in the first group underwent cervical stabilization (CS) exercises and additional scapular and lumbopelvic stabilization (SLPS) exercises three times a week for 6 weeks. The second group was treated with only CS exercises for the same period. In addition, stretching exercises and a 20-minute hot pack were applied to the muscles around the neck of all patients.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercises
Description: Individuals in the first group underwent cervical stabilization (CS) exercises and additional scapular and lumbopelvic stabilization (SLPS) exercises three times a week for 6 weeks. The second group was treated with only CS exercises for the same period. In addition, stretching exercises and a 20-minute hot pack were applied to the muscles around the neck of all patients.
Study: NCT05884385

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simulated exercises
Description: as detailed in arm description

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mental Visualisation
Description: as detailed in arm description
Study: NCT06576258

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: cobas eplex multiplex PCR
Description: Positive blood culture samples from the intervention group are subjected to cobas eplex multiplex PCR in addition to the SOC culture methods.
Study: NCT06576297

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inspiratory Muscle Training (IMT)
Description: IMT using a PrO2™ inspiratory training device will incorporate the Test of Incremental Respiratory Endurance (TIRE)9 technology to achieve an optimized exercise training regimen.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Standard of Care Participants in the usual care group will be telephoned at 4 and 8 weeks, and AE/SAE will be reviewed.
Study: NCT05880875

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reflective Supervision Enhancement
Description: The Reflective Supervision enhancement is a professional development series designed to train and support directors and education coordinators supervising state pre-kindergarten classrooms in using a reflective supervision approach with their staff.
Study: NCT06155955

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Emicizumab, HEMLIBRA®
Description: low dose
Study: NCT05049889

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Swimming exercise
Description: At visit 2 (Day 7), the subjects will perform a swimming exercise in the experimental pool equipped with a turbine to create a counter-current. The water speed will be constant (4 min per 100 m, i.e. 1.5 km/h). The duration of the exercise will be 30 minutes. Each diver will breathe with the help of a snorkel.~During this exercise, continuous data collection will be performed:~* Continuous 12-lead electrocardiogram~* Continuous monitoring of blood pressure and ventilation.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Swimming exercise
Description: At visit 2 (Day 7), the subjects will perform a swimming exercise in the experimental pool equipped with a turbine to create a counter-current. The water speed will be constant (4 min per 100 m, i.e. 1.5 km/h). The duration of the exercise will be 30 minutes. Each diver will breathe with the help of a snorkel.~During this exercise, continuous data collection will be performed:~* Continuous 12-lead electrocardiogram~* Continuous monitoring of blood pressure and ventilation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transthoracic cardiac ultrasound
Description: The participants will have a transthoracic cardiac ultrasound to measure the dilatations of the cardiac cavities at visit 1 and 2.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transthoracic cardiac ultrasound
Description: The participants will have a transthoracic cardiac ultrasound to measure the dilatations of the cardiac cavities at visit 1 and 2.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transthoracic pulmonary ultrasound
Description: The participants will have a transthoracic pulmonary ultrasound to quantify the presence of signs of pulmonary vascular overload (comet tails) at visit 1 and 2.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transthoracic pulmonary ultrasound
Description: The participants will have a transthoracic pulmonary ultrasound to quantify the presence of signs of pulmonary vascular overload (comet tails) at visit 1 and 2.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood collection
Description: Several blood samples will be collected at visit 1 and 2.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood collection
Description: Several blood samples will be collected at visit 1 and 2.
Study: NCT06270849

Intervention type: OTHER
Intervention: Questionnaire
Description: The questionnaire to assess severity of LUTS in women.

Intervention type: OTHER
Intervention: Questionnaire
Description: The questionnaire to assess severity of LUTS in women.
Study: NCT05414071

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NMS Assist
Description: The system enables people with Parkinson's and their care partners to complete questionnaires about symptoms and burden and share that information with their care team. They can also access self-help resources and materials about managing non-motor symptoms. Healthcare providers have a dashboard that flags any worsening symptoms or discrepancies between PwP and CP reports, enabling their to prioritise care and quickly see the status of their patients. The system also enables PwP or CPs to request healthcare contact.
Study: NCT06295458

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: David Delight Plus Device
Description: Flicker exposure via a light and sound device-based stimulation-provided sensory stimulation device. The DAVID Delight Plus device consists of light-emitting goggles and sound-emitting headphones that are turned on and off with a repetition rate of 40 Hz connected to a controller operated by the participant or study partner (if the participant elects to have an optional study partner). At the baseline visit, light and sound intensity levels (auditory: 0-80 dBA, visual: 0-1400 lux) will be programmed into each participant's controller based on their unique response to tolerance and EEG entrainment testing which occurred at screening. The participant may not detect gamma-flicker frequency.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Therapy
Description: Sham therapy will be provided in the same manner as the flicker light. The difference is that it will be a constant light and sound from the same device instead of the 40hz light treatment and sound.
Study: NCT06154733

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Photobiomodulation usinf low level laser therapy
Description: Diode laser will be used (SIROLaser Blue®, Sirona, Germany) at a wavelength of 660 nm and a power of 100 mW for 10 sec, corresponding to an energy dose of 1 J. Irradiation will be performed at the hypomineralized area: two irradiations scanning the surface in the mesiodistal direction and two in the occlusogingival direction (perpendicular to the tooth surface) precisely over the lesion, in a uniform scanning motion with relative isolation. Treatment will be performed in 3 sessions with a 72-hour interval between sessions.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Resin-based sealant
Description: Cotton rolls and a four-handed technique will be applied for isolation. Scotchbond Universal will be rubbed in the cleaned surface for 20 seconds and air dried for 5 seconds. Afterwards, Fissured Novo Plus will be applied with a syringe. Before light-curing, the presence of air bubbles will be checked and teased out. Light curing for 40 seconds will be done. Occlusion will be checked using articulating paper and necessary adjustments will be done using finishing burs.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Glass ionomer sealant
Description: Fuji triage will be applied after activating and mixing the capsule. Light cure for 20 seconds. Occlusion will be checked using articulating paper and necessary adjustments will be done using finishing burs.~For the duration of the study, children will be instructed to undergo regular tooth brushing and flossing. Any other needed treatment will be done for the child.
Study: NCT05535777

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced texts with Callback by a Person
Description: Enhanced texts - Callback by a person: Patient randomized to this study arm will receive a phone call back by a call center agent if they press 1 in response to a question on the original text message. The call center agent's job is to schedule patients for clinical visits. These call center agents will be trained by our faculty and staff and will have the usual HIPAA and other patient confidentiality training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Bidirectional Texts
Description: Patients randomized to this study arm will receive a text message from a call center agent if they press 1 in response to a question on the original text message. The bidirectional texts will have an agent who can answer questions and schedule an appointment through text message back-and-forth conversations with the patient.
Study: NCT05898802

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Kimchi
Description: Two different kimchi, one traditional kimchi and one fermented with a lactic acid bacteria having anti-obesity effect, hereafter starter kimchi, are flash freeze dried, powdered and encapsulated.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Kimchi
Description: Two different kimchi, one traditional kimchi and one fermented with a lactic acid bacteria having anti-obesity effect, hereafter starter kimchi, are flash freeze dried, powdered and encapsulated.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Lactose with kimchi flavor
Study: NCT06340334

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tegoprazan-amoxicillin dual therapy
Description: A total of 600 Hp-positive patients who had not received Hp eradication therapy before or had had Hp eradication in the early stage but had not undergone eradication therapy in the past six months were randomly divided into two groups: group A subjects received Tegoprazan 50 mg, bid + amoxicillin 1000 mg, tid; Group B subjects received Tegoprazan 50 mg, bid + amoxicillin 1000 mg, bid + furazolidone 100 mg, bid + colloidal pectin bismuth 300 mg, bid. The duration of treatment is 14 days. The eradication rate, adverse reactions, and compliance of the two groups were compared.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Tegoprazan-amoxicillin dual therapy
Description: A total of 600 Hp-positive patients who had not received Hp eradication therapy before or had had Hp eradication in the early stage but had not undergone eradication therapy in the past six months were randomly divided into two groups: group A subjects received Tegoprazan 50 mg, bid + amoxicillin 1000 mg, tid; Group B subjects received Tegoprazan 50 mg, bid + amoxicillin 1000 mg, bid + furazolidone 100 mg, bid + colloidal pectin bismuth 300 mg, bid. The duration of treatment is 14 days. The eradication rate, adverse reactions, and compliance of the two groups were compared.
Study: NCT04259411

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MitraClip procedure
Description: MitraClip procedure with MitraClip NTR System or MitraClip XTR System
Study: NCT05610397

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX

Intervention type: DEVICE
Intervention: STALIF®
Description: STALIF® C, or M, Ti or FLX
Study: NCT06382181

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music therapy for community-dwelling individuals with unwanted loneliness
Description: Music therapy workshops were implemented. The enjoyment and expression of feelings were encouraged by listening to songs, singing, dancing, guided relaxation with music, and group instrumental performance. There was one session per week. Total 12 sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health education for community-dwelling individuals with unwanted loneliness
Description: Twelve health education workshops were carried out. They included group training talks on the following topics: sleep hygiene, diet, and cognitive stimulation, among others.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical exercise for community-dwelling individuals with unwanted loneliness
Description: This intervention was implemented with 2 group sessions each week for 13 weeks. It included physical exercise adapted to the physical conditions of each participant.