TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06536062

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intravitreal injection of CB-PRP
Description: The procedure consists in a trans-scleral puncture to access the vitreous cavity, with subsequent injection of CB-PRP

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intravitreal injection of CB-PRP
Description: The procedure consists in a trans-scleral puncture to access the vitreous cavity, with subsequent injection of CB-PRP

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intravitreal injection of CB-PRP
Description: The procedure consists in a trans-scleral puncture to access the vitreous cavity, with subsequent injection of CB-PRP
Study: NCT04634357

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ET140203 T Cells
Description: Biological/Vaccine: ET140203 autologous T-cell product~Autologous T cells transduced with lentivirus encoding an ET140203 expression construct
Study: NCT05400096

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychological therapy
Description: The protocol for the group will be developed collaboratively between the chief researcher and the supervisor based in the weight management service. The protocol will contain Compassion Focused Therapy (CFT) based therapeutic approaches, but the group will integrate some Acceptance and Commitment Therapy (ACT) concepts.
Study: NCT06439537

Intervention type: OTHER
Intervention: Semi-structured questionnaire
Description: All patients recruited to the study will undergo a semi-structured questionnaire within 36 hours of admission

Intervention type: OTHER
Intervention: Post-operative interview
Description: All patients recruited to the study will undergo a semi-structured interview once they have reached post-operative day 7 or over
Study: NCT06102005

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lunsekimig
Description: Pharmaceutical form: solution for injection Route of administration: subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lunsekimig
Description: Pharmaceutical form: solution for injection Route of administration: subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lunsekimig
Description: Pharmaceutical form: solution for injection Route of administration: subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lunsekimig
Description: Pharmaceutical form: solution for injection Route of administration: subcutaneous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form: solution for injection Route of administration: subcutaneous
Study: NCT06057701

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: corrective exercises
Description: corrective exercises:~1. Strengthening exercises :~   1. Thoracic extension exercises:~      * Mckanzie's thoracic extension exercise:~     * Thoracic spine stretching position~  2. Back extension exercise~  3. Abdominal curl up exercise~  4. Scapular retraction exercises~  5. Trunk rotation exercise~2. Stretching exercises:~   1. Pectoral muscles stretch from sitting~  2. self-stretch for pectoral muscle infront of door

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: corrective exercises
Description: corrective exercises:~1. Strengthening exercises :~   1. Thoracic extension exercises:~      * Mckanzie's thoracic extension exercise:~     * Thoracic spine stretching position~  2. Back extension exercise~  3. Abdominal curl up exercise~  4. Scapular retraction exercises~  5. Trunk rotation exercise~2. Stretching exercises:~   1. Pectoral muscles stretch from sitting~  2. self-stretch for pectoral muscle infront of door

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: resisted diaphragmatic breathing exercises
Description: 1. Diaphragmatic breathing exercise: From the supine position, overlapping hands on the diaphragm located in the abdominal region: each woman took deep inspiring by the nose and exhaling through the mouth with lips half-closed slowly.~2. Resisted diaphragmatic breathing exercise: From the supine position, with a weight of 1 kg on the diaphragm located in the abdominal region: each woman took deep inspiring by the nose and exhaling through the mouth with lips half-closed slowly
Study: NCT05876221

Intervention type: DRUG
Intervention: Cablivi
Description: Patients with immune Thrombotic Thrombocytopenic Purpura, who have been treated with caplacizumab (Cablivi®)
Study: NCT05556512

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study: NCT04832724

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: RGX-314
Description: RGX-314 is a recombinant adeno-associated virus gene therapy vector carrying a coding sequence for a soluble anti-VEGF protein

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: RGX-314
Description: RGX-314 is a recombinant adeno-associated virus gene therapy vector carrying a coding sequence for a soluble anti-VEGF protein

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: RGX-314
Description: RGX-314 is a recombinant adeno-associated virus gene therapy vector carrying a coding sequence for a soluble anti-VEGF protein

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: RGX-314
Description: RGX-314 is a recombinant adeno-associated virus gene therapy vector carrying a coding sequence for a soluble anti-VEGF protein
Study: NCT06166095

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high-dose
Description: Participants will be asked to perform a high-dose (HD) (i.e., 300 minutes of MVPA per week) of structured exercise for 10 weeks. Exercise modality and schedule will be participant- selected and may consist of any combination of aerobic and strength training that elevates the heart rate between 64 - 95 percent of estimated heart rate max

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Walking attention control
Description: The attention control group will be asked to wear the Fitbit activity tracker to monitor their sleep each night for 10 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: moderate-dose
Description: Participants will be asked to perform a moderate-dose (MD) (i.e., 150 minutes of MVPA per week) of structured exercise for 10 weeks. Exercise modality and schedule will be participant- selected and may consist of any combination of aerobic and strength training that elevates the heart rate between 64 - 95 percent of estimated heart rate max
Study: NCT05469503

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 12 weeks of placebo supplementation
Study: NCT06232369

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active repetitive deep transcranial magnetic stimulation (dTMS)
Description: Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is accurately delivered to the intended target by an optic navigation and a deep pulse protocol at 90% of the tested threshold for 15-minute stimulation duration.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham repetitive deep transcranial magnetic stimulation (dTMS)
Description: Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is placed on the scalp to mimic the sensation and sounds of the actual treatment but without letting the magnetic field reach the brain tissue for 15-minute duration.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham repetitive deep transcranial magnetic stimulation (dTMS)
Description: Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is placed on the scalp to mimic the sensation and sounds of the actual treatment but without letting the magnetic field reach the brain tissue for 15-minute duration.
Study: NCT05294198

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beetroot extract
Description: Beetroot extract capsule

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Beetroot extract
Description: Beetroot extract capsule
Study: NCT05285917

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxyurea
Description: Hydroxyurea has a narrow therapeutic window such that selection of the correct dose is essential to optimize benefits and avoid toxicity.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hydroxyurea
Description: Hydroxyurea has a narrow therapeutic window such that selection of the correct dose is essential to optimize benefits and avoid toxicity.
Study: NCT06537856

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Belief Model Based Cardiovascular Disease Risk Factor Prevention Education
Description: In line with the literature review, Health Belief Model-Based Cardiovascular Disease Risk Factor Prevention Training was created in order to increase the level of knowledge of firefighters regarding cardiovascular disease risk factors, improve their awareness and positively affect their quality of life. This training was given in 3 different sessions by meeting face-to-face with firefighters in the training hall of the fire stations. Each session lasted 40 minutes. Answers were given to the questions asked at the end of the session. The training was organized under the following main headings:~Perceived Sensitivity, Perceived Seriousness, Perceived Barriers, Perceived Self-Efficacy, Health Motivation/Activators

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reminder Short Messages
Description: After the Health Belief Model-Based health education, 39 text messages were sent via WhatsApp application 3-4 times a week for 3 months to increase the effectiveness of the education and the motivation of firefighters in CVD prevention.
Study: NCT05764902

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient-tailored intervention
Description: The intervention group will receive various tailored interventions designed to address multiple patient preferences, including sleeping, eating, and resting habits, hobbies, visitation preferences, religious and spiritual needs, preferences for independence and privacy, and any other specific requests or requirements.
Study: NCT05787860

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ruxolitinib 1.5% Cream
Description: topical ruxolitinib 1.5% cream twice daily for 4 weeks
Study: NCT05880420

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Caregiver operations with medication accessories
Description: After at least an initial outpatient medication (24/72 hours), home medication every 7 days (caregiver) for a total of 10 weeks.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nurse operations with medication accessories
Description: Outpatient medication every week (for a total of 10 weeks). Patients adhering to this arm will be followed at the IGAV nursing clinic of the IFOs.
Study: NCT04870931

Intervention type: PROCEDURE
Intervention: TEM / TEM-ESD
Description: Transanal local excision of a rectal tumour as a conventional, full-thickness TEM or submucosal dissection as TEM-ESD

Intervention type: PROCEDURE
Intervention: TEM / TEM-ESD
Description: Transanal local excision of a rectal tumour as a conventional, full-thickness TEM or submucosal dissection as TEM-ESD
Study: NCT06073184

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mounjaro
Description: Tirzepatide injection, starting dose is 2.5mg injected subcutaneously once weekly. After 4 weeks, dose should be increased to 5mg once weekly. The dose then can be increased in 2.5mg increments after no less than 4 weeks on current dose to maximum dose of 15mg once weekly.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirena
Description: Levonorgestrel-releasing Intrauterine System (52mg) to deliver up to 20 mcg levonorgestrel per day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirena
Description: Levonorgestrel-releasing Intrauterine System (52mg) to deliver up to 20 mcg levonorgestrel per day
Study: NCT06138431

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT
Description: Virtual CBT groups
Study: NCT06519955

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
Description: Weight 50-74.9 kg:~* ropivacaine 100mg/epinephrine 50 mcg/ketorolac 15mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total~Weight 75-99.9 kg:~* Ropivacaine 150mg/epinephrine 100 mcg/ketorolac 15mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total~Weight 100+ kg:~* Ropivacaine 200mg/epinephrine 150 mcg/ketorolac 15 mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
Description: Weight 50-74.9 kg:~* ropivacaine 100mg/epinephrine 50 mcg/ketorolac 15mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total~Weight 75-99.9 kg:~* Ropivacaine 150mg/epinephrine 100 mcg/ketorolac 15mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total~Weight 100+ kg:~* Ropivacaine 200mg/epinephrine 150 mcg/ketorolac 15 mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total
Study: NCT05457335

Intervention type: PROCEDURE
Intervention: undergoing PGT
Description: Preimplantation genetic testing for aneuploidy

Intervention type: PROCEDURE
Intervention: undergoing PGT
Description: Preimplantation genetic testing for aneuploidy
Study: NCT06373419

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TFL
Description: Participant undergoing bladder tumour resection that has been randomized to this arm.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MOSES holmium laser
Description: Participant undergoing bladder tumour resection that has been randomized to this arm.
Study: NCT06125873

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Moringa + Metformin - Moringa 1 gm and Metformin 500 mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Moringa + Metformin - Moringa 1 gm and Metformin 500 mg
Study: NCT05588375

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: home-based physical activity telemonitoring program
Description: The home telehealth physical activity training program is a telemedicine physical activity training that uses Google Meet software to communicate and supervise through webcams.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: home-based physical activity telemonitoring program
Description: The home telehealth physical activity training program is a telemedicine physical activity training that uses Google Meet software to communicate and supervise through webcams.
Study: NCT05467449

Intervention type: DEVICE
Intervention: DxFLEX 10C
Description: A device combining flow cytometry and reagents for immunophenotyping analysis

Intervention type: DEVICE
Intervention: DxFLEX 10C
Description: A device combining flow cytometry and reagents for immunophenotyping analysis
Study: NCT05397522

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Exercise by a physiotherapist via face to face
Description: The exercises are performed by the participants under the supervision of a physiotherapist via face-to-face.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Exercise by a physiotherapist via video conference
Description: The exercises are performed by the participants under the supervision of a physiotherapist via video conference.
Study: NCT05799495

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07817883
Description: Arm 1: low dose Arm 2: medium dose Arm 3: high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07817883
Description: Arm 1: low dose Arm 2: medium dose Arm 3: high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07817883
Description: Arm 1: low dose Arm 2: medium dose Arm 3: high dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06283979

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: STIMULAN VG
Description: Insertion of STIMULAN VG into the ulcer cavity prior to flap closure.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Standard of Care. Ulcer bursectomy, debridement and flap closure. Peri-operative antibiotics.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Standard of Care. Ulcer bursectomy, debridement and flap closure. Peri-operative antibiotics.
Study: NCT06477445

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Visual feedback balance training system
Description: Using an visual feedback balance training system to provide a dynamic balance training platform for patients to perform balance training based on visual feedback.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: repetitive facilitative exercise
Description: Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: repetitive facilitative exercise
Description: Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: Basic training, including passive joint movement and activities of daily living exercise.
Study: NCT05124457

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Detemir
Description: Patients are to receive insulin detemir

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin NPH
Description: Patients are to receive insulin NPH
Study: NCT05648591

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iloperidone
Description: oral tablet
Study: NCT06572371

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic pyeloplasty
Description: The first trocar was inserted under vision through the same supraumbilical incision and the intraperitoneal cavity was inspected The second 5 mm trocar was placed in the midclavicular line 2 inches below the costal margin. The third 10 mm trocar was placed lateral to the rectus muscle at the level of the anterior superior iliac spine. In right-sided pyeloplasty, a fourth trocar was inserted below the xiphistemum for liver retraction. Incision of the line of Toldt and mobilization of the colon was the first step of the transperitoneal approach. A 4/0 polysorbe stay suture was taken in the lateral aspect of the ureter distal to uretero-pelvic junction obstruction to identify the correct orientation after dismembering the ureter. A full thickness anastomosis was started from the angle of V shape spatulation to the lower pole of the renal pelvis.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open pyeloplasty
Description: A flank incision with the patient in lateral position was undertaken in open pyeloplasty. After accessing the retro- peritoneum, the ureter was identified and traced cranially till the PUJ segment.~Traction sutures was placed on the renal pelvis followed by excision of the narrowing segment. The ureter was spatulated by approximately 2 cm and a reduction pyeloplasty was performed, where necessary. Anastomosis was undertaken using vicryl 4-0 sutures. The primary anastomotic site was sutured in interrupted fashion followed by a continuous running suture of the posterior wall. Next, antegrade DJ stenting was performed and the anterior wall was anastomosed. After haemostatic control a 22 Fr drain was placed in the surgical bed.
Study: NCT04906018

Intervention type: DEVICE
Intervention: Ultrasound scans
Description: Each subject will be randomly allocated to an ultrasound machine and an expert scanner who will perform the ultrasound scans of all supported anatomical regions.

Intervention type: DEVICE
Intervention: Ultrasound scans
Description: Each subject will be randomly allocated to an ultrasound machine and an expert scanner who will perform the ultrasound scans of all supported anatomical regions.
Study: NCT05668195

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: systematic aerobic exercise and intelligent monitoring system in executive skill training
Description: This is a closed-loop training initially developed by the research team in conjunction with other teams, adding a systematic aerobic exercise and intelligent monitoring system to the typical executive skill training, and is being further explored in training.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: executive skill training
Description: The training program, based on Dawson and Guare's (2010) training of executive skills for children, aimed to improve the everyday performance of executive skills among children with ADHD. Qian Y and her team added some culturally adapted information, following the theory of cognitive behavioral therapy, to ensure that the concepts were acceptable to Chinese children.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: executive skill training
Description: The training program, based on Dawson and Guare's (2010) training of executive skills for children, aimed to improve the everyday performance of executive skills among children with ADHD. Qian Y and her team added some culturally adapted information, following the theory of cognitive behavioral therapy, to ensure that the concepts were acceptable to Chinese children.
Study: NCT05023915

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dexamethasone
Description: 40 mg qd for 4 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: diammonium glycyrrhizinate enteric-coated capsule
Description: 150mg tid for 3 months