TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04568226

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ConquerFear Intervention
Description: ConquerFear is a manualized intervention, consists of six individual sessions over 10 weeks. The key goals of this intervention are the following: (1) teach strategies for controlling worry and excessive threat monitoring, (2) modify underlying unhelpful beliefs about worry, (3) develop appropriate monitoring and screening behaviours, (4) encourage acceptance of the uncertainty brought about by a cancer diagnosis, and (5) clarify values and encourage engagement in values-based goal setting (19). Each session will last 60-90 minutes and be delivered by a trained therapist. After each session, participants will be given home-based exercises to practice the skills learned in the sessions. With the uncertainty surrounding the COVID-19 pandemic, instead of face-to-face sessions only, a hybrid mode of intervention delivery will be used by offering participants the choice of face-to-face or online sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active control: Basic Cancer Care
Description: Basic Cancer Care intervention for the control arm was developed to help cancer survivors with health maintenance in long-term through providing comprehensive lifestyle guidance. The intervention incorporates relaxation training, dietary and physical fitness consultations with the key goals to (1) teach relaxation techniques, (2) offer personalized diet and physical activity advice, and (3) enhance survivors' perceived control over illness, thereby leading to better adjustment to cancer. Similar to the ConquerFear intervention, Basic Cancer Care intervention consists of 6 individual sessions over 10 weeks. Each session will last 60-90 minutes and be delivered by a trained therapist, a registered dietitian, and an exercise physiologist, respectively. A hybrid mode of intervention delivery will be also used by offering participants the choice of face-to-face or online sessions.
Study: NCT05853614

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Quality of Life Intervention
Description: Comprised of three components: (1) establishment of clinical research nurse (CRN) and patient relationship, (2) assessment and monitoring of physical, psychological, social, and spiritual well-being and patient-reported outcomes, and (3) weekly, interdisciplinary team meetings led by CRN.
Study: NCT02590380

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MESA Rail Deformity System
Description: The spinal deformity will be correction via a standard of care procedure performed by the principal investigator. The correction will be fixated with the MESA Rail Deformity System.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DePuy Synthes USS II System
Description: The spinal deformity will be correction via a standard of care procedure performed by the principal investigator. The correction will be fixated with the DePuy Synthes USS II system.
Study: NCT06492096

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bibloc Mandibular Advancement device
Description: Each patient received a CAD/CAM designed Bibloc Mandibular Advancement device

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bibloc Mandibular Advancement device
Description: Each patient received a CAD/CAM designed Bibloc Mandibular Advancement device
Study: NCT05846776

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DigiPrehab system
Description: Using an Artificial Intelligence-Machine Learning (AI-ML) DSS platform, which analyzes a large collection of data (screening and local data) from different sources, the DigiPrehab system will allow to predict the risk of falling in the elderly subjects. Once the screening will be completed, to carry out the prevention of falls, the system will assign to the participants a personalised exercise program that the patient will carry out at home for 12 weeks. The exercises will be chosen from the following: squat at door, squat on chair, squat with knee-lift, squat with heel-raise, stand-no support, toe-raise with support, toe-raise, one leg balance, weight-shift with support, weight-shift without support, lunge with support, lunge, step on book, step over book, step onto box or stair, step forward-sideways, step forward-sideways-backwards, knee to elbow, timed up and go.
Study: NCT05427266

Intervention type: OTHER
Group type: OTHER
Intervention: Tap Block - Bupivacaine
Description: The medicinal product for both groups is the same - Bupivacaine. The mode of administration is what this study is reviewing: Control group (Standard port site infiltration) and Study Group - Laparoscopic Transversus Abdominis Plane Block (LTap Block)

Intervention type: OTHER
Group type: OTHER
Intervention: Tap Block - Bupivacaine
Description: The medicinal product for both groups is the same - Bupivacaine. The mode of administration is what this study is reviewing: Control group (Standard port site infiltration) and Study Group - Laparoscopic Transversus Abdominis Plane Block (LTap Block)
Study: NCT05847894

Intervention type: DIAGNOSTIC_TEST
Intervention: Ophthalmic examination
Description: Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ophthalmic examination
Description: Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.

Intervention type: DIAGNOSTIC_TEST
Intervention: Pulmonary Examination
Description: Various pulmonary examination modalities, including radiography, chest CT, pulmonary function measurement, etc.

Intervention type: DIAGNOSTIC_TEST
Intervention: Pulmonary Examination
Description: Various pulmonary examination modalities, including radiography, chest CT, pulmonary function measurement, etc.
Study: NCT05343065

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BlueStar 10
Description: An app that coaches individuals with diabetes and supports insulin-dosing based on continuous glucose monitor data
Study: NCT05066243

Intervention type: OTHER
Intervention: questionnaire
Description: this study is to develop a questionnaire for vulval conditions
Study: NCT06317194

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: kTMP
Description: A new non-invasive brain stimulation tool

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham kTMP
Description: A new non-invasive brain stimulation tool with sham setting selected
Study: NCT06312072

Intervention type: OTHER
Intervention: No intervention; observational study
Description: No intervention; observational study

Intervention type: OTHER
Intervention: No intervention; observational study
Description: No intervention; observational study
Study: NCT04405050

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Restrata
Description: Restrata® is a novel synthetic nanofabricated scaffold (Restrata Wound Matrix (RWM), Acera Surgical, St. Louis, Missouri) has been developed which is a sterile, single-use device intended for use in the local management of wounds. The RWM is a soft, white, conformable, non-friable, absorbable matrix that acts as a protective covering for wound defects, providing a moist environment for the body's natural healing process to occur (Figure 2). The RWM is made from synthetic biocompatible materials and was designed to include a fibrous structure with high porosity, similar to native ECM. As a viable wrap for surgical procedures, Restrata conforms to injured tissue, can be sutured, and is arthroscopic and robotic procedure friendly.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Negative Pressure Wound Therapy (NPWT)
Description: Negative Pressure Wound Therapy (NPWT) has dramatically changed the care of complex foot wounds. Compared to standard wound care, patients with diabetic foot wounds that are treated with NPWT are 5.9 times more likely to heal and 4.4 times less likely to require amputation. NPWT involves the delivery of sub-atmospheric pressure through a vacuum pump connected to a specialized dressing to maintain a closed environment. NPWT increases perfusion to the wound, accelerates granulation tissue formation, reduces edema, and reduces bio-burden
Study: NCT05751356

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TR128
Description: TR128 will be given daily for 28 days in 28-day cycles until there appears evidence of progressive disease, intolerable toxicity, or the subject discontinues from the study treatment for other reasons. Starting dose is 100mg, with escalation to 500mg.
Study: NCT06216444

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam Tosilate for Injection
Description: Initial loading dose of 5mg, with additional doses of 2.5mg as necessary

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam Tosilate for Injection
Description: Initial loading dose of 10mg, with additional doses of 2.5mg as necessary
Study: NCT06549374

Intervention type: OTHER
Intervention: blood sampling
Description: After informing eligible patients (or their trusted support person, relative/guardian/curator where applicable) and in the absence of any opposition, they are included in the research.~Blood samples from an arterial catheter already in place will be taken every day from D1 to D7, then every 72 hours until discharge from intensive care, or until D28. For each of these samples, a maximum volume of 4 ml will be collected in a heparinized tube. Samples will not be taken if the hemoglobin level is below 7g/dl. For patients undergoing controlled surgery, the D1 sample will be taken as soon as possible after induction of anaesthesia.~Patients will be monitored until discharge from intensive care, or until D28 at the latest. Apart from the blood samples included in this study, all other examinations will be carried out as part of routine management. Data will be collected exclusively from medical records.
Study: NCT05754346

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Complete Decongestive Therapy
Description: Complete Decongestive Therapy will include manual lymphedema drainage (self) for 20 min everyday, skin care everyday, wearing compression garment or bandages everyday and upper-extremity exercises twice a day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Complete Decongestive Therapy
Description: Complete Decongestive Therapy will include manual lymphedema drainage (self) for 20 min everyday, skin care everyday, wearing compression garment or bandages everyday and upper-extremity exercises twice a day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Upper extremity exercises combined with diaphragmatic breathing exercises
Description: Upper-extremity exercises component of Complete Decongestive Therapy will be performed combined with diaphragmatic breathing exercises.
Study: NCT04926272

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-92
Description: Intravenous injection of one dose of 0.10mCi/kg(±5%) 18F-92. Each subject receive a single intravenous injection of 18F-92, and undergo PET/CT imaging within the specificed time.
Study: NCT06222840

Intervention type: OTHER
Intervention: Electro-clinical analysis of epileptic seizures
Description: Electro-clinical analysis of epileptic seizures

Intervention type: OTHER
Intervention: Electro-encephalographic cases
Description: Electro-encephalographic connectivity analysis compared to controls

Intervention type: OTHER
Intervention: Clinical datas analysis
Description: Clinical datas analysis

Intervention type: OTHER
Intervention: Electro-encephalographic control
Description: Electro-encephalographic connectivity analysis compared to cases
Study: NCT04899232

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antithrombin III
Description: Five total doses of daily 1,821 to 9,100 IUs Antithrombin III, depending on participant's weight, will be administered intravenously every other infusion day (Days 1, 3, 5, 7 and 9).
Study: NCT05687461

Intervention type: OTHER
Intervention: Build a national diagnosis and treatment quality control platform for major respiratory diseases
Description: 1. Build a national diagnosis and treatment quality control platform for major respiratory diseases~2. To master the incidence trend and diagnosis and treatment quality of major respiratory diseases~3. Promotion of standardized diagnosis and treatment techniques for major respiratory diseases

Intervention type: OTHER
Intervention: Build a national diagnosis and treatment quality control platform for major respiratory diseases
Description: 1. Build a national diagnosis and treatment quality control platform for major respiratory diseases~2. To master the incidence trend and diagnosis and treatment quality of major respiratory diseases~3. Promotion of standardized diagnosis and treatment techniques for major respiratory diseases
Study: NCT06144983

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alvogyl
Description: In the first study group, (0.2gm) of Alvogyl paste (Septodont Inc., France), was inserted inside the alveolus, filling it entirely

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chlorhexidine Gluconate
Description: in the second group (1ml) of Periokin (Kin Inc., Spain), containing 0.2% Chlorhexidine bioadhesive gel was injected to fill the entire socket
Study: NCT04934787

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ENMS-BSF assisted gait training
Description: 1. ENMS-BSF will correct the foot-drop and foot inversion during post-stroke walking.~2. Each participant will receive 20 sessions device assisted training, with an intensity of 3-5 sessions/week, 1 hr/session.~3. In each session, a participant will complete the device-assisted walking on flat ground with a natural speed and with the aid of a four-pronged cane.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ENMS-BSF assisted gait training
Description: 1. ENMS-BSF will correct the foot-drop and foot inversion during post-stroke walking.~2. Each participant will receive 20 sessions device assisted training, with an intensity of 3-5 sessions/week, 1 hr/session.~3. In each session, a participant will complete the device-assisted walking on flat ground with a natural speed and with the aid of a four-pronged cane.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: ENMS-BSF assisted gait training
Description: 1. ENMS-BSF will correct the foot-drop and foot inversion during post-stroke walking.~2. Each participant will receive 20 sessions device assisted training, with an intensity of 3-5 sessions/week, 1 hr/session.~3. In each session, a participant will complete the device-assisted walking on flat ground with a natural speed and with the aid of a four-pronged cane.
Study: NCT06000293

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral health education
Description: Anticipatory Guidance (AG) provided to the primary caregivers-infant pairs in the intervention group
Study: NCT05855447

Intervention type: OTHER
Intervention: NIRS device usage during 6MWT
Description: It will be performed by placing a traffic cone as the sign of the turning point in a straight 30 meter long corridor, after patients have rested for a sufficient time (\> 30 minutes) by sitting in a chair. Participants will be asked to walk as fast as possible but without running along the corridor within 6 minutes. Before and after the test, the patient's fatigue and dyspnea conditions will be questioned using the Modified Borg Scale and blood pressure using a digital sphygmomanometer, and saturation and pulse measurement will be evaluated using finger pulse oximetry before, during and after the test. During the 6-minute walk test, the muscle oxygenation of the patients and the amount of muscle oxygen will be measured using Moxy (Fortiori Design LLC, Minnesota, USA) brand NIRS technology. During the walking test, the change in intramuscular oxygenation will be monitored and recorded with the company's software program.

Intervention type: OTHER
Intervention: Peripheral Muscle Strength Measurement
Description: The muscle strength of shoulder flexors, abductors, elbow flexors, hip flexors, abductors, and knee extensors will be evaluated using a Lafayette® 01165 model electronic hand dynamometer. The force measurement will be repeated 3 times and it will be requested to maintain muscle strength against the dynamometer for at least 5 seconds in each trial. The best value out of 3 test results will be recorded

Intervention type: OTHER
Intervention: Pulmonary Function Test
Description: Pulmonary Function Test (PFT) with desktop type spirometry for FVC (Forced Vital Capacity), Forced expiratory flow rate (FEV1), FEV1/FVC.
Study: NCT06548906

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR4 Injection
Description: GZR4 Injection administered sc, once weekly.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR4 Injection
Description: GZR4 Injection administered sc, once weekly.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR4 Injection
Description: GZR4 Injection administered sc, once weekly.
Study: NCT05196854

Intervention type: OTHER
Group type: OTHER
Intervention: Group 1. Standard Home Blood Pressure Measurement
Description: Measurement of Blood Pressure using Home blood pressure monitor

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group 2. Hypnosis script prior to home blood pressure measurement
Description: Pre-recorded clinical hypnosis script (approx 5 mins long) used prior to standard home blood pressure measurement. Clinical Hypnosis is used as a non-pharmacological technique for reducing procedural anxiety, distress and discomfort with patients.
Study: NCT06176937

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic acid
Description: Alveolar ridge preservation by atraumatic tooth extraction and socket curettage then application hyaluronic acid gel after extraction and covering the socket by collagen membrane.

Intervention type: OTHER
Group type: OTHER
Intervention: empty socket
Description: Alveolar ridge preservation by atraumatic tooth socket without application any drug but just covering the socket by collagen membrane.
Study: NCT05558956

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: illuccix 68Ga-PSMA-11 Total Body PET-CT
Description: Illuccix (kit for the preparation of gallium Ga 68 gozetotide injection) 68Ga-PSMA-11

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: illuccix 68Ga-PSMA-11 Total Body PET-CT
Description: Illuccix (kit for the preparation of gallium Ga 68 gozetotide injection) 68Ga-PSMA-11
Study: NCT06240390

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided percutaneous neuromodulation (NMP)
Description: Epte Bipolar System is a medical device for health professionals that combines several techniques that extend the therapeutic variety of electrostimulation, for the treatment of different pathologies of the musculoskeletal system and peripheral and central nervous system. It is a nationally manufactured device that meets all quality standards, being the perfect tool for the application of techniques such as transcranial direct current stimulation. It is a versatile, compact, portable and easy to use equipment that has the ability to adapt the parameters to achieve any protocol established by scientific evidence to treat the various pathologies. The Epte® Bipolar System device has an CE Health Certificate
Study: NCT05512533

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Linear Ultrasound Bronchoscope BF-UC290F (Olympus)
Description: A thin Olympus EBUS bronchoscope BF-UC290F will be used for all endobronchial ultrasound examinations, and biopsies will be conducted with EBUS needles - the ViziShot 2 22G (Olympus).
Study: NCT04943705

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Yin and Yang Regulating Moxibustion
Description: Before making Wenyang Yishen moxibustion, the width and length of the patient's moxibustion site were evaluated by the same body measurement method. Take about 700g of fresh ground ginger with moderate dryness and wetness, and place it on the treatment towel to make a round cake with a diameter of about 20cm and a thickness of about 2.5cm. Spread 25g of moxa moxa with a diameter of about 18cm on top of ginger and light it. When the bottom temperature reaches about 37 degrees, the door can be placed on the patient's waist for treatment. According to the patient's tolerance, the temperature should be controlled at 43-45 degrees. It is better to replace the moxa biscuit every time when the moxa biscuit is burned for about 10 minutes. The patient's local skin has a slight redness and burning. The moxibustion time is 60 minutes. Peiyuan Guben moxibustion is centered on Shenque, and the operation is the same as that of WenYang and Yishen moxibustion.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Yin and Yang Regulating Moxibustion
Description: Before making Wenyang Yishen moxibustion, the width and length of the patient's moxibustion site were evaluated by the same body measurement method. Take about 700g of fresh ground ginger with moderate dryness and wetness, and place it on the treatment towel to make a round cake with a diameter of about 20cm and a thickness of about 2.5cm. Spread 25g of moxa moxa with a diameter of about 18cm on top of ginger and light it. When the bottom temperature reaches about 37 degrees, the door can be placed on the patient's waist for treatment. According to the patient's tolerance, the temperature should be controlled at 43-45 degrees. It is better to replace the moxa biscuit every time when the moxa biscuit is burned for about 10 minutes. The patient's local skin has a slight redness and burning. The moxibustion time is 60 minutes. Peiyuan Guben moxibustion is centered on Shenque, and the operation is the same as that of WenYang and Yishen moxibustion.
Study: NCT06211231

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digitally delivered mindfulness- and acceptance-based psychological intervention
Description: MY-ENDO is developed specifically for endometriosis and includes ten themes; one for each session: 1) endometriosis, 2) chronic pain and pain mechanisms, 3) stress, 4) thoughts and feelings, 5) grief, 6) identity and meaning, 7) everyday life and relations, 8) health, diet and exercise, 9) value-based action and 10) a good life with endometriosis.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digitally delivered mindfulness- and acceptance-based psychological intervention
Description: MY-ENDO is developed specifically for endometriosis and includes ten themes; one for each session: 1) endometriosis, 2) chronic pain and pain mechanisms, 3) stress, 4) thoughts and feelings, 5) grief, 6) identity and meaning, 7) everyday life and relations, 8) health, diet and exercise, 9) value-based action and 10) a good life with endometriosis.
Study: NCT06240390

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pharmacological treatment by Opioids
Description: Opioid analgesics are the main option for pain treatment in cancer patients, but their side effects and inadequate treatment lead to cheaper, quicker options with lower risk of addiction and/or side effects.
Study: NCT04786119

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CORI Robotics
Description: Knee arthroplasty with robotics assisted surgery using the CORI Robotics System.
Study: NCT05124184

Intervention type: DEVICE
Intervention: GORE® PROPATEN® Vascular Graft
Description: Patients that have had treatment with GORE® PROPATEN® Vascular Graft