TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06516666

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music
Description: Participants went through four stages. In the rest stage, they were instructed to relax. In the neutral control stage, they watched an informative video about plastic injection molding. In the sadness induction stage, they viewed sad clips from either Hachi: A Dog's Tale or My Brother and Sister, with the order randomized across participants. In the music intervention stage, they listened to the cheerful Cuckoo Waltz. Each stage lasted for about 6 minutes.~The interventions for the two groups were exactly same.~PS: On the basis of the PHQ-9, this HAMD interview was conducted to further group the participants. So, following the experimental protocol, participants who scored ≥ 5 on the PHQ-9 measure underwent the HAMD interview, while the remaining individuals were simply interviewed about their feelings during the experiment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music
Description: Participants went through four stages. In the rest stage, they were instructed to relax. In the neutral control stage, they watched an informative video about plastic injection molding. In the sadness induction stage, they viewed sad clips from either Hachi: A Dog's Tale or My Brother and Sister, with the order randomized across participants. In the music intervention stage, they listened to the cheerful Cuckoo Waltz. Each stage lasted for about 6 minutes.~The interventions for the two groups were exactly same.~PS: On the basis of the PHQ-9, this HAMD interview was conducted to further group the participants. So, following the experimental protocol, participants who scored ≥ 5 on the PHQ-9 measure underwent the HAMD interview, while the remaining individuals were simply interviewed about their feelings during the experiment.
Study: NCT05390424

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood collection using Dried Blood Spot
Description: Drug users will be screened for Hepatitis C, Hepatitis B and AIDS using Dried Blood Spot for blood collection
Study: NCT04783532

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telehealth Mindfulness Program
Description: Enrolled participants will participate in an individual (one-on-one) Telehealth-delivered (online with audio and video) mindfulness intervention with a trained mindfulness therapist. The intervention is adapted from mindfulness-based cognitive therapy and includes eight sessions lasting 75 minutes each (except the first session which lasts 90 minutes) over a 3-month period.
Study: NCT06008444

Intervention type: OTHER
Intervention: Physical Evaluations of post-COVID-19 individuals
Description: In this research, the data of Parkinson's patients who have had COVID-19 will be collected face to face. Chest mobility, cough strength, muscle strength, physical activity and quality of life will be evaluated in all Parkinson's patients. The data to be obtained through all these evaluations will be collected from at one time and in a time lasting maximum of about 1 hour. Step count tracking with pedometer will be done for 3 days for each individual.

Intervention type: OTHER
Intervention: Physical Evaluations of non-post-COVID-19 individuals
Description: In this research, the data of Parkinson's patients who have not had COVID-19 will be collected face to face. Chest mobility, cough strength, muscle strength, physical activity and quality of life will be evaluated in all Parkinson's patients. The data to be obtained through all these evaluations will be collected from at one time and in a time lasting maximum of about 1 hour. Step count tracking with pedometer will be done for 3 days for each individual.
Study: NCT04743245

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TherOx DownStream System
Description: SSO2 Therapy with Therox downstream System after Percutaneous Coronary Intervention (PCI)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PCI
Description: Standard Care of PCI

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PCI
Description: Standard Care of PCI
Study: NCT04657016

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study: NCT04798963

Intervention type: PROCEDURE
Group type: OTHER
Intervention: On-clamp partial nephrectomy
Description: Partial nephrectomy will performed with renal artery clamping (less than or equal to 25 minutes)
Study: NCT04962906

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gam-COVID-Vac / Gam-COVID-Vac
Description: A comparison of antibody levels against protein S will be performed using the Gam-COVID-Vac / Gam-COVID-Vac group as a control group and the Gam-COVID-Vac / ChAdOx1 nCoV-19 and Gam-COVID-Vac / BBIBP-CorV groups as comparators.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gam-COVID-Vac / Gam-COVID-Vac
Description: A comparison of antibody levels against protein S will be performed using the Gam-COVID-Vac / Gam-COVID-Vac group as a control group and the Gam-COVID-Vac / ChAdOx1 nCoV-19 and Gam-COVID-Vac / BBIBP-CorV groups as comparators.
Study: NCT05747131

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Detectives In-Out
Description: Emotion Detectives In-Out is a blended cognitive-behavioral intervention for children with emotional disorders aged between 7 to 12 years and their parents. It contains group sessions, online self-guided sessions and videoconference sessions. The groups will consist of about 5 to 7 children. Face-to-face sessions have an expected duration of 90 minutes and will be implemented by clinical psychologists with specific training in the program. The online sessions were developed by the research team and are completely self-guided. These sessions last approximately 45 minutes. Parents will be asked to participate in 2 face-to-face sessions, 4 videoconference sessions and 10 self-guided online sessions. It is a transdiagnostic and emotion-focused manualized cognitive-behavioral therapy designed to help children reduce the intensity and frequency of strong and aversive emotional experiences and to help parents reduce parental emotional behaviors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Coping Cat
Description: Coping Cat is a cognitive behavioral therapy for children with anxiety aged between 7 to 13 years. Coping Cat consists of 16 weekly group sessions with the children (5 to 7 children per group) and 2 sessions with the parents. Face-to-face sessions have an expected duration of 90 minutes and will be implemented by clinical psychologists.
Study: NCT05596409

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elacestrant
Description: Starting dose 400 mg elacestrant dihydrochloride administered orally once daily for an estimated 6 months of treatment.
Study: NCT04962906

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gam-COVID-Vac / Gam-COVID-Vac
Description: A comparison of antibody levels against protein S will be performed using the Gam-COVID-Vac / Gam-COVID-Vac group as a control group and the Gam-COVID-Vac / ChAdOx1 nCoV-19 and Gam-COVID-Vac / BBIBP-CorV groups as comparators.
Study: NCT05086198

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based intervention
Description: An instructor trained in Mindfulness-based Stress Reduction (MBSR; Kabat-Zinn, 1990) will conduct meditations lasting 15 to 30 minutes. The participants will have a mobile application designed ad hoc with the practice of the week so they can do it individually at home.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical exercise
Description: An aerobic and fitness trainer will conduct aerobic exercise lasting 15 to 30 minutes. The participants will watch it in a video platform. They will not be able to do anaerobic exercise like weight lifting. The intensity of the chosen exercise will be moderate, maintaining between 120-140 beats per minute.
Study: NCT06380166

Intervention type: DIAGNOSTIC_TEST
Intervention: Hepatitis C core antigen
Description: Semi-quantitative, automated immunoassay detecting core antigen of hepatitis C virus.
Study: NCT04902612

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HM242-Solution
Description: HM242-Solution compared to Saline compared in patients with a venous leg ulcer

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Saline
Description: HM242-Solution compared to Saline compared in patients with a venous leg ulcer
Study: NCT06451588

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FMT
Description: Active FMT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FMT
Description: Active FMT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FMT
Description: Active FMT

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo treatment will be prepared based on the patients' fecal samples (autologous).
Study: NCT05879757

Intervention type: OTHER
Intervention: No Intervention
Description: As this is an observational study, no intervention will be administered in this study.
Study: NCT06123299

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: pHyph
Description: vaginal tablet
Study: NCT06639789

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin B12 (B12)
Description: The new formulation of vitamin B12 will be ingested 3 days before and on the day of testing (3 hours before).

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: PLACEBO (PLA)
Description: The placebo will be ingested 3 days before and the same day of the tests (3 hours before).
Study: NCT06564805

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Candida Albicans Antigen Injection
Description: subcutaneous administration of Candida albicans antigen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Candida Albicans Antigen Injection
Description: subcutaneous administration of Candida albicans antigen
Study: NCT06563947

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Oral enterobacterium capsules
Description: Enterobacterium capsules (300 mg/per capsule) orally 6 capsules/day for 10 consecutive days.
Study: NCT05284643

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity Modulated Proton Therapy (IMPT)
Description: Participants will receive radiation therapy delivered via intensity modulated proton therapy (IMPT) simultaneous integrated boost technique over a period of 10 days, 5 days per week for approximately 2 weeks.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity Modulated Proton Therapy (IMPT)
Description: Participants will receive radiation therapy delivered via intensity modulated proton therapy (IMPT) simultaneous integrated boost technique over a period of 10 days, 5 days per week for approximately 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab will be administered intravenously (IV), beginning at a dose of 10 mg/kg every 2-3 weeks until disease progression.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab will be administered intravenously (IV), beginning at a dose of 10 mg/kg every 2-3 weeks until disease progression.
Study: NCT05789251

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Standardized breakfast
Description: Standardized breakfast to replace in fine oral induced hyperglycemia test
Study: NCT05523908

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: High-dose hypofraction Arm
Description: Patients in this arm would receive high-dose fractionated radiotherapy with 60Gy/15f

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Low-dose hypofraction Arm (Standard BED)
Description: Patients in this arm would receive low-dose fractionated radiotherapy with 48Gy/12f
Study: NCT05590663

Intervention type: OTHER
Intervention: Physiotherapy
Description: routine referral-based physiotherapy treatment for patients with knee osteoarthritis
Study: NCT04747301

Intervention type: DEVICE
Group type: OTHER
Intervention: Double-balloon catheter (UTAH CVX-RIPE) for cervical ripening
Description: Sweeping the membranes by UTAH CVX-RIPE® (Utah Medical Products, Inc, 7043 South 300 West, Midvale, Utah 84047 USA). The catheter will be inserted manually until the proximal balloon is in the cervical canal, the distal balloon should be intrauterine and in the extra-amniotic space. The intrauterine balloon is inflated with 40mL saline and retracted so that it rests against the internal oz. The proximal balloon should now be outside the external oz and is inflated with 20mL saline. If the balloons are correctly situated on both ends of the cervix, they can be inflated with up to 80mL saline each.~Cardiotocograph will be performed 30min, 2 hours after insertion and every 6 hours. The balloon is placed for a maximum of 24 hours.~If it is expelled in the first 12 hours and the patient has no contractions or still shows an unfavorable cervix, another balloon is placed for a maximum of another 24 hours.~The patients will be examined in case of extremely painful or membranes ruptured.

Intervention type: DRUG
Group type: OTHER
Intervention: Dinoprostone 10mg (Propess)
Description: Propess® 10mg Vaginal delivery system (Ferring Controlled Therapeutics Ltd., 1 Redwood Place, Peel Park Campus, East Kilbride, Glasgow, G74 5PB, UK) is a vaginal insert containing 10mg of dinoprostone in a timed-release formulation (the medication is released at 0.3 mg/hour).~A Propess vaginal system is inserted by a research doctors. As in the catheter procedure, Fetal Heart Rate is monitored 30min before and 2 hours after placement. Cardiotocograph and vaginal examination will be performed every 6 hours. The vaginal system is placed for a maximum of 24 hours.~If it is expelled in the first 12 hours and the patient has no contractions or still shows an unfavorable cervix, another vaginal system is placed for a maximum of another 24 hours.~The patients will be examined in case of extreme pain or membranes ruptured.
Study: NCT04798963

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Off-clamp partial nephrectomy
Description: Partial nephrectomy will performed without renal artery clamping
Study: NCT04875975

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rozanolixizumab
Description: * Pharmaceutical form: Solution for infusion~* Route of administration: Subcutaneous use~Subjects will receive rozanolixizumab in a pre-specified sequence during the Treatment Period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: * Pharmaceutical form: Solution for infusion~* Route of administration: Subcutaneous use~Subjects will receive placebo in a pre-specified sequence during the Treatment Period.
Study: NCT06440369

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training group
Description: The patient will perform an intermittent exercise which consists of nine 5-minute cycles with a succession of work (top: 1 minute; bottom: 4 minutes). The high-intensity work phase will be adjusted so as to achieve a target Heart Rate (HR) corresponding to resting HR + 80% reserve HR (reserve HR = (200 - age) - resting HR). The low-intensity work phase will be adjusted to achieve a target maximum HR corresponding to resting HR + 60% reserve HR. In total duration, the exercise presents a submaximal intensity, commonly used in exercise rehabilitation studies carried out with various pathologies. It is an intensity capable of promoting benefits on the cardiovascular aspect without representing a severe intensity for the patient.~In order to adapt the training and guarantee patient safety, the first exercise session will be carried out with an alternation between a high-intensity work phase of resting HR + 70% reserve HR and a work phase. at low intensity of resting HR + 50% reserve HR.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical activity orientation group
Description: Every week, for around ten minutes, patients in the AP orientation group will be contacted by telephone. The main objective of this exchange is to provide targeted advice on physical activity, its role, its objectives as well as its different ways of carrying it out. The second objective is to provide each week a personalized objective for each patient which can evolve over the weeks to increase levels of physical activity as far as possible. During each call, the evaluator will practice reflective listening, ask open-ended questions to facilitate the exchange, value and summarize the patient.
Study: NCT05094999

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Proprioceptive stimulations
Description: Vibration treatment will last eight weeks for each patient, with 4 sessions per week, 30 minutes per session. Subjects of the intervention group will receive proprioceptive stimulations set to create illusions of movement.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulations
Description: Vibration treatment will last eight weeks for each patient, with 4 sessions per week, 30 minutes per session. Subjects of the control group will receive sham stimulations.
Study: NCT05103748

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional vestibular rehabilitation
Description: The patient shook his head horizontally and looked in the direction of head rotation. Repeated 10 times, and then shook his head with eyes closed and repeated 10 times. The patient holds a small visual target to practice. The small visual target is placed about 30cm in front of the patient. The subject moves his head back and forth while keeping his sight on the target.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive and vestibular dual task training
Description: The patient shook his head horizontally and looked in the direction of head rotation. Repeated 10 times, and then shook his head with eyes closed and repeated 10 times. The patient holds a small visual target to practice. The small visual target is placed about 30cm in front of the patient. The subject moves his head back and forth while keeping his sight on the target. Besides, patients wear headphones to listen to the numbers at the same time. The numbers contain 1 and 2, and they are played randomly. They shake their heads when they hear 1, and nod when they hear 2. The training takes 30 minutes, once a day in the morning and evening.
Study: NCT05127551

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iStent Infinite
Description: Implantation of the iStent Infinite

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Competitor Device
Description: Implantation of competitor device
Study: NCT05146817

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral care
Description: Treatment group - original protocol of oral care: special device for tooth brushing 3 times a day with chlorhexidine . Control group - traditional protocol of oral care ( traditional tooth brushing 1 time a day + chlorhexidine rinsing

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oral care
Description: Treatment group - original protocol of oral care: special device for tooth brushing 3 times a day with chlorhexidine . Control group - traditional protocol of oral care ( traditional tooth brushing 1 time a day + chlorhexidine rinsing
Study: NCT05915754

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hip abductors stretching and strengthening exercises
Description: Treatment consist of four stretches for the ITB including: ITB stretch with trunk side bend, ITB stretch with trunk side bend and upward lateral reach, trunk side bend with downward lateral reach and side lying leg adduction and Strengthening exercise plan involving the gluteal muscle groups. These exercises include clams, side-lying abduction, reverse clams and supine bridge
Study: NCT05702996

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eculizumab administration
Description: Patient with Thrombotic microangiopathies induced by gemcitabine will be treat with Eculizumab
Study: NCT06345417

Intervention type: OTHER
Intervention: Patient Blood Management (PBM)
Description: PBM is a strategy to manage the participant's own blood. Its focus is on anemia, bleeding and coagulation management.

Intervention type: OTHER
Intervention: Patient Blood Management (PBM)
Description: PBM is a strategy to manage the participant's own blood. Its focus is on anemia, bleeding and coagulation management.

Intervention type: BIOLOGICAL
Intervention: Allogeneic transfusion
Description: Anemia is treated by administering donor red cells, and bleeding or coagulopathy by plasma, platelets or other donor blood products.

Intervention type: BIOLOGICAL
Intervention: Allogeneic transfusion
Description: Anemia is treated by administering donor red cells, and bleeding or coagulopathy by plasma, platelets or other donor blood products.
Study: NCT06333132

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight loss-induced Diabetes Remission
Description: Patients will undergo a dietary intervention plus drugs (if needed) with the purpose to obtain a 10% (or at least 10 kg) body weight reduction to achieve diabetes remission
Study: NCT04626544

Intervention type: DEVICE
Intervention: Body-worn inertial sensors
Description: The device typically includes accelerometers that capture body accelerations in three directions (anteroposteriorly, mediolaterally and vertically) and gyrometers that capture rotations (yaw, pitch and roll). The method of measuring gait using body-worn inertial sensors has been found reliable \[15\] and valid \[20\]. This project will use Opal sensors and the Mobility Lab software from the manufacturer APDM (https://www.apdm.com/wearable-sensors/).

Intervention type: DEVICE
Intervention: Body-worn inertial sensors
Description: The device typically includes accelerometers that capture body accelerations in three directions (anteroposteriorly, mediolaterally and vertically) and gyrometers that capture rotations (yaw, pitch and roll). The method of measuring gait using body-worn inertial sensors has been found reliable \[15\] and valid \[20\]. This project will use Opal sensors and the Mobility Lab software from the manufacturer APDM (https://www.apdm.com/wearable-sensors/).
Study: NCT05589350

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: saturated fat intake
Description: Intake of saturated fat from yogurt and animal butter daily for 4-week period

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: saturated fat intake
Description: Intake of saturated fat from yogurt and animal butter daily for 4-week period
Study: NCT00860678

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical activity

Intervention type: OTHER
Group type: OTHER
Intervention: no Intervention
Study: NCT06468306

Intervention type: PROCEDURE
Intervention: non-invasive ventilation teraphy, NIV
Description: Routine management regimes of NIV