TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05020613

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Procedure: Early removal group
Description: Participants assigned this arm will have their urethral catheters removed at 2 days after low anterior resection of the rectum

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Procedure: Late removal group
Description: Participants assigned this arm will have their urethral catheters removed after 48.th hours after Low anterior resection of the rectum
Study: NCT05806112

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resiliency Training
Description: The Stress Management and Resiliency Training: Relaxation Response Resiliency Program (SMART-3RP) has been shown to be effective in improving resilience and reducing distress among individuals across different populations and settings. The SMART-3RP enhances resilience by 1) teaching tools to elicit the relaxation response (RR) to offset negative effects of chronic stress; 2) improving stress management and awareness; and 3) promoting growth enhancement and agency to effect positive change. It blends stress coping principles from mind-body, cognitive-behavioral, and positive psychology theory to teach skills to advance each of these resiliency processes. The training will be delivered in six 50-minute virtual group sessions with 2 optional booster sessions available for those who desire additional sessions to further consolidate the core resiliency skills.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Task Sharing
Description: Task Sharing is a process involving health care workers in partnership with others in which workers retain many of their primary tasks, but some tasks are completed collaboratively or by other workers or volunteers in a shared effort. Study coaches will work with the group home directors and RCWs to identify shared tasks that may be conducted by peers or resident volunteers by task co-assignment with supervision and support. Task co-assignments will be discussed in routine house meetings occurring on a weekly basis and incorporated into a jointly developed house plan. The house plan will engage staff and residents to identify shared activities to reduce the burden on RCWs through task co-assignment and team-based efforts aimed at tasks that create unnecessary burden and stress for RCWs, yet do not require RCWs to complete them.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Workplace Improvement Learning Collaborative
Description: The Workplace Improvement Learning Collaborative (WILC) consists of identifying major sources of RCW burnout across the system and then instituting an organizational (agency-wide) measure to address the identified sources of burnout by restructuring tasks (e.g., reducing administrative burdens, increasing workflow efficiencies) through a virtual earning collaborative with group home leaders. Learning collaboratives commonly use a structured framework within which teams learn about research and best practices, apply quality-improvement methods, and exchange their experiences in making improvements with the widespread use of such collaboratives. Program Directors will participate in a learning collaborative facilitated by trained and certified study coaches to identify and collaboratively develop and implement effective strategies to address root causes of RCW burnout across group homes and program directors assigned to the WILC intervention.
Study: NCT05969379

Intervention type: GENETIC
Intervention: Analysis of biomarkers and their correlation with clinical characteristics and outcome
Description: This is a non-interventional study involving clinical data, neuroimaging analysis, and biological samples. Demographics and clinical data are collected in the database of the French Reference Centre. Additional or missing data will be obtained by contacting the referral physicians. All the neuroimages available will be analysed by dedicated software. Samples are already stored in biobank repositories and collected as part of good clinical practice in the diagnostic process of patients with suspected autoimmune encephalitis, meaning that the standard diagnostic and therapeutic approaches will not be altered in the selected study population. Patients have already gave explicit written consent for biological specimens sampling and storage at the Centre de Ressources Biologiques des Hospices Civils de Lyon (CRB-HCL) (including tissue, cells or biological fluids). Additional samples for genetic testing will be collected upon explicit written consent.
Study: NCT04767672

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: the subjects will consume 2 bags of 10 grams per day of the product: 1 bag in the morning and 1 bag at lunch or in the evening, at the beginning of the meal, diluted in a large glass of beverage, during 12 weeks.
Study: NCT04777604

Intervention type: OTHER
Intervention: Organoid
Description: The investigators create organoid from the pancreatic cancer tissue obtained via EUS-FNA and EUS-FNB within the pancreatic cancer diagnostic process. And also the investigators create organoid from the pancreatic cancer tissue obtained after surgery as part of the pancreatic cancer treatment process. Check for the reactivity to anti-cancer drugs through cell viability assay after treating with various anti-cancer drugs, such as anti-cancer drugs used as neoadjuvant chemotherapy for pancreatic cancer to the organoid. Also, perform genomic analysis on each organoid, and then check if there are any unique genomic mutations for each organoid. By recognizing the relationship between the unique genomic mutations and reactivity to the anti-cancer drug within patients with resectable pancreatic cancer after neoadjuvant chemotherapy, the investigators aim to strategize appropriate neoadjuvant chemotherapy before surgery, thus developing a platform to predict the outcomes of each patient.
Study: NCT06364384

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PD-1 and CRT
Description: Chemotherapy (/3w): 1)DDP 75 mg/m2, d1, intravenous infusion; 2)5-FU 1000 mg/m2, d1-4, continuous pumping intravenously; Immunotherapy (/3w): PD-1 monoclonal antibody(sintilimab) 200mg, d1, intravenous infusion; Radiotherapy (at 3rd week after first time of chemotherapy):Daily single dose of 2Gy, with a total dose of 50-54GY.
Study: NCT04656288

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764198 - Formula A
Description: BI 764198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764198 - Formula B
Description: BI 764198
Study: NCT06411613

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CC Program
Description: The CC Program will be delivered through the existing HBPC infrastructure at VA Puget Sound Health Care System. Each HBPC team is comprised on a lead physician or nurse practitioner, nurse, pharmacist, nutritionist, social worker, psychologist, therapist, and chaplain. At a minimum, subsequent clinical encounters and assessments for each Veteran will be scheduled no less than on a quarterly basis and more often as needed based on the HBPC team's clinical judgment. On a monthly basis, the entire HBPC team will conduct MDC meetings to review each Veteran's medical plan. The Program aims to provide patient-centered, whole-person and team-based care, shared decision-making, active symptom management, advance care planning and end-of-life care.
Study: NCT04656288

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764198 - Formula B
Description: BI 764198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764198 - Formula B
Description: BI 764198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764198 - Formula C
Description: BI 764198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764198 - Formula D
Description: BI 764198
Study: NCT06219668

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Omentopexy group
Description: Omentopexy and Clips on staple line during LSG

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Omentopexy group
Description: Omentopexy and Clips on staple line during LSG
Study: NCT05767788

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Movement with Mobilization (MWM)
Description: Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior glide, is applied to the knee of the patient.~Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Movement with Mobilization (Sham MWM)
Description: Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior light-touch glide, is applied to the knee of the patient.~Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.
Study: NCT03752203

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Fluorescein
Description: Patients enrolled in this study will receive 3 mg/kg sodium fluorescein following induction of anesthesia by administration into a peripheral venous line over 10 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microscopic Resection
Description: Resection will proceed with the use of a surgical microscope equipped with excitation and barrier filters for monitoring with sufficient fluorescent enhancement and contrast.
Study: NCT05568563

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethyl chloride
Description: Ethyl chloride is an agent that is widely used in dental practice as the standard modality for pulp vitality tests .

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Honey
Description: Honey is a natural dietary product
Study: NCT05618756

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Acute oral CBD supplementation
Description: 1 ml hemp oil containing 300 mg CBD, within gelatin capsules, ingested orally.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Acute oral placebo supplementation
Description: 1 ml hemp oil containing no CBD, within gelatin capsules, ingested orally.
Study: NCT06555341

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Six Thinking Hats Group
Description: 2. Subcutaneous insulin administration was explained with the traditional training model.~3. The Six Thinking Hats technique and how it is used was then explained in detail to the students. Any points that were not fully understood were explained again so that the technique was thoroughly reinforced.~4. The researchers had made hats from different coloured card. All the students wore all the hats in turn and were asked the questions related to that colour hat as stated above (semi-structured questionnaire 1-6).~5. The responses given by the students to the questions were audio-recorded. Each interview lasted 30 mins.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Other: Video Group
Description: 2. Subcutaneous insulin administration was explained with the traditional training model.~3. Then by scanning the QR code from the nursing practice skills textbook(Aylaz \&amp; Yakıncı, 2024), the researchers provided the link for the students to watch the insulin application video.~4. Without mentioning hat colours or the Six Thinking Hats method to this group, the questions on the semi-structured questionnaire were asked, and the interviews, each lasting 30 mins, were audio-recorded.~5. After completing the video training, the mid-test data were collected by applying the Subcutaneous Insulin Application Skill Level Observation Form during administration of insulin to a dummy.
Study: NCT04902625

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Naltrexone-Bupropion Combination
Description: Naltrexone-bupropion will be added to the BOT module in the interventional arm.
Study: NCT05075720

Intervention type: DIETARY_SUPPLEMENT
Group type: SHAM_COMPARATOR
Intervention: Meat with added nitrate
Description: The intervention comprises 50 g salami and 35 g ham on white bread sandwich at breakfast and lunch.~This intervention will allow us to determine both endogenous formation of N-nitrosamines as well as N-nitrosamines present in the commercially prepared meat.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Meat with added nitrate
Description: The intervention comprises 50 g salami and 35 g ham on white bread sandwich at breakfast and lunch.~This intervention will allow us to determine both endogenous formation of N-nitrosamines as well as N-nitrosamines present in the commercially prepared meat.

Intervention type: DIETARY_SUPPLEMENT
Group type: SHAM_COMPARATOR
Intervention: Meat without added nitrate
Description: The intervention comprises 65 g Pork mince on white bread sandwich at breakfast and lunch. Nitrate is not an allowed additive in pork mince.~This intervention will allow us to determine if there is endogenous formation of N-nitrosamines as well as N-nitrosamines present in the prepared meat due to the natural content of nitrate in meat.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Meat without added nitrate
Description: The intervention comprises 65 g Pork mince on white bread sandwich at breakfast and lunch. Nitrate is not an allowed additive in pork mince.~This intervention will allow us to determine if there is endogenous formation of N-nitrosamines as well as N-nitrosamines present in the prepared meat due to the natural content of nitrate in meat.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Control
Description: The control comprises low nitrate vegetable protein burger on white bread. Protein content matched to interventions 1 and 2.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Control
Description: The control comprises low nitrate vegetable protein burger on white bread. Protein content matched to interventions 1 and 2.
Study: NCT05845489

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clopidogrel treatment group
Description: Patients assigned to the clopidogrel treatment group will maintain clopidogrel 75mg once a day for at least 5 years.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No antiplatelet or anticoagulant group
Description: Patients assigned to the no antiplatelet or anticoagulant group will not prescribe antithrombotics for at least 5 years. However, when there is a medical need for antithrombotic therapy during the follow-up, the prescription of antithrombotics is permitted with reporting to the research board.
Study: NCT06404164

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Wedge resection under watershed analysis method
Description: * Compare the preoperative 3D reconstruction model, and use electrocautery to directionally separate and expose the target artery;~  * Auxiliary devices (unlimited) to block the target artery, but should not be severed; ③ Peripheral intravenous injection of ICG, electrocautery to mark the border of counter-staining; ④ Evaluate the actual incisal margin according to the preoperative planning, and use the cutting stapler to wedge resection of the pulmonary nodule
Study: NCT05783648

Intervention type: DRUG
Intervention: Use of tranexamic acid
Description: Percentage of correct use according to POISE-3 criteria of tranexamic acid

Intervention type: DRUG
Intervention: Use of tranexamic acid
Description: Percentage of correct use according to POISE-3 criteria of tranexamic acid
Study: NCT05046639

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10 mL 2% lidocaine
Description: Image guided sciatic nerve anesthetic block of the contralateral limb with an injection of 10 mL 2% lidocaine.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 10 mL preservative free saline
Description: Image guided sciatic nerve anesthetic block of the contralateral limb with an injection of 10 mL preservative free saline.
Study: NCT06278571

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational intervention with App and web site education
Description: This group will only receive intervention with access to the educational website from home, where they will review the different modules focused on diabetes care, nutrition and exercise. in addition to the usual medical care by your treating physician.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational interventión with web site education
Description: This group will receive, in addition to nutritional therapy, diabetes education through an educational site, to learn more about the most important aspects of diabetes care. In addition to the usual medical care by your treating physician.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational interventión with web site education
Description: This group will receive, in addition to nutritional therapy, diabetes education through an educational site, to learn more about the most important aspects of diabetes care. In addition to the usual medical care by your treating physician.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group with nutritional therapy
Description: This group will receive only the usual medical care by your treating physician.
Study: NCT05019820

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Knee strengthening exercises with isokinetic dynamometer
Description: 18 sessions of strengthening exercises around the knee with an isokinetic dynamometer 3 days a week

Intervention type: OTHER
Group type: OTHER
Intervention: Strengthening around the knees with home exercise programe
Description: 18 sessions of strengthening exercises for the muscles around the knee at home, 3 days a week
Study: NCT05727917

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hetrombopag
Description: After hematopoietic stem cell reinfusion, the patients begin to take hetrombopag orally 7.5mg/d, until the patients reach complete platelet response.The treatment will stop when patients accept 21 consecutive days of treatment or reach the discontinuation criteria.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: After hematopoietic stem cell transfusion, the patients will be only observed, and the observation during the treatment period will be ended after 30 days
Study: NCT05904691

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCU-10-C-110 for Injection
Description: OCU-10-C-110 for Injection in one of 3 doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCU-10-C-110 for Injection
Description: OCU-10-C-110 for Injection in one of 3 doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCU-10-C-110 for Injection
Description: OCU-10-C-110 for Injection in one of 3 doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCU-10-C-110 for Injection
Description: OCU-10-C-110 for Injection in one of 3 doses
Study: NCT04698655

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Recommendation from general practitioner
Description: Receive a hypothetical general practitioner recommendation for exercise

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information on osteoarthritis
Description: Asked to read 1 A4 page of brief information on osteoarthritis

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Information on osteoarthritis
Description: Asked to read 1 A4 page of brief information on osteoarthritis

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Information on osteoarthritis
Description: Asked to read 1 A4 page of brief information on osteoarthritis
Study: NCT05235906

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib+Sintilimab
Description: Surufatinib at a dose of 250mg Qd, with humanized anti-PD-1 monoclonal antibody Sintilimab injected intravenously 200mg per 3 weeks until disease progresses or unacceptable tolerability occurs.
Study: NCT04892797

Intervention type: OTHER
Intervention: Covid-19+ observational
Description: This is observational--there is no intervention
Study: NCT04641065

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music listening
Description: An expert on the particular type of music will do the selection of the playlist of Traditional Turkish Military music, and this playlist will be listened to the patients by the researchers.
Study: NCT05167604

Intervention type: DRUG
Intervention: Adjuvants, Pharmaceutic
Description: Patients with stage IB-IIA NSCLC after curative surgery were treated with adjuvant chemotherapy. The blood samples of the patients before and after adjuvant chemotherapy will be collected to examine the MRD status

Intervention type: DRUG
Intervention: Adjuvants, Pharmaceutic
Description: Patients with stage IB-IIA NSCLC after curative surgery were treated with adjuvant chemotherapy. The blood samples of the patients before and after adjuvant chemotherapy will be collected to examine the MRD status
Study: NCT06047392

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: CT coronary angiography
Description: Patients will undergo a CTCA according to local, standard protocol.
Study: NCT06074081

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: motor relearning program
Description: MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior .

Intervention type: OTHER
Group type: OTHER
Intervention: mirror therapy
Description: Mirror therapy enhance functional activities in patient with hemiplegic stroke. For betterment of result high quality methodological studies and larger sample size is required.
Study: NCT05885191

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 2H intrinsically-labeled T.molitor with 13-C labeled amino acid mixture
Description: Test meal with dried 2H intrinsically labeled T.molitor and 13C labeled reference amino acid mixture will be divided into 10 portions, which will be given hourly over the course of 7 hours. The first consumption will be the priming meal, comprised of 3 portions and will additionally contain 13C sodium bicarbonate.
Study: NCT06095336

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telerehabilitation
Description: The individuals included in the research will be divided into three groups. Group 1 (experiment): This is the exercise group followed by the telerehabilitation method. Group 2 (experiment): This is the group where traditional physical therapy methods will be applied. The 3rd group will be taken as the control group, there will be no intervention and they will be asked to continue their daily lives.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telerehabilitation
Description: The individuals included in the research will be divided into three groups. Group 1 (experiment): This is the exercise group followed by the telerehabilitation method. Group 2 (experiment): This is the group where traditional physical therapy methods will be applied. The 3rd group will be taken as the control group, there will be no intervention and they will be asked to continue their daily lives.
Study: NCT04505293

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: InfraScanner 2000™
Description: The Infrascanner is a portable screening device that uses Near-Infrared (NIR) technology to screen patients for intracranial bleeding, identifying those who would most benefit from immediate referral to a CT scan and neurosurgical intervention.