TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04898296

Intervention type: OTHER
Intervention: Questionnaire, Interview
Description: During the stay, a study visit is arranged with the patient after the 6-minute walk test has been performed. This consists of filling out the questionnaire and an interview, which lasts about 45-60 minutes. This is carried out by the investigator on at least 5 subjects. After each interview, a list of influencing factors is kept. If new aspects continue to appear in the 5th interview, the interviews are continued (up to a maximum of the 10th subject). If no new aspects appear in the interviews from number 6 onwards, the interviews are discontinued and no further patients are recruited. The conversations are recorded with an audio recording.

Intervention type: OTHER
Intervention: Focus Group
Description: The focus group is carried out first in order to identify influencing variables that may be relevant for the interview (duration 60-90 minutes).
Study: NCT05045118

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Structured Patient Education Material
Description: Participants of home-based Cardiac Rehabilitation Program that are included in this research will be provided with a digital Structured Patient Education Material at the beginning of the program, and will be followed up for 12 weeks duration
Study: NCT05498805

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiation
Description: According to the lesion sites, SBRT or hyperfractionated radiotherapy was used.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation
Description: According to the lesion sites, SBRT or hyperfractionated radiotherapy was used.
Study: NCT05830019

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: carbon ion radiotherapy
Description: carbon ion radiotherapy
Study: NCT04946877

Intervention type: DIAGNOSTIC_TEST
Intervention: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III)
Description: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III): is consists of several subtests, each classified into a verbal or performance scale .

Intervention type: DIAGNOSTIC_TEST
Intervention: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III)
Description: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III): is consists of several subtests, each classified into a verbal or performance scale .
Study: NCT06263348

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dorzagliatin tablets
Description: During the study, patients should follow the dosing instructions from the investigator, which are made according to the package insert and the patients' conditions.
Study: NCT06199297

Intervention type: DRUG
Intervention: Atezolizumab combined with Bevacizumab
Description: Atezolizumab 1200 mg IV d1, Q3W, combined with bevacizumab 15 mg/kg IV d1, Q3W treatment, treatment continued until disease progression, development of intolerable toxic reactions

Intervention type: DRUG
Intervention: Sintilimab combined with Bevacizumab
Description: Sintilimab 200 mg IV d1, Q3W, combined with bevacizumab 15 mg/kg IV d1, Q3W treatment, treatment continued until disease progression, development of intolerable toxic reactions

Intervention type: PROCEDURE
Intervention: Transcatheter arterial chemoembolization and hepatic arterial infusion chemotherapy
Description: The chemoembolization process employed 30 mg/m2 of epirubicin and 2-10 mL of lipiodol. This was followed by FOLFOX-based HAIC, including 85 mg/m2 of oxaliplatin, 400 mg/m2 of leucovorin, and an initial bolus of 400 mg/m2 of 5-FU for 2 h, which was then followed by a sustained infusion of 1200 mg/m2 5-FU for 23 h.

Intervention type: PROCEDURE
Intervention: Transcatheter arterial chemoembolization and hepatic arterial infusion chemotherapy
Description: The chemoembolization process employed 30 mg/m2 of epirubicin and 2-10 mL of lipiodol. This was followed by FOLFOX-based HAIC, including 85 mg/m2 of oxaliplatin, 400 mg/m2 of leucovorin, and an initial bolus of 400 mg/m2 of 5-FU for 2 h, which was then followed by a sustained infusion of 1200 mg/m2 5-FU for 23 h.
Study: NCT04983706

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MRI/Ultrasound Fusion Saturation Biopsy
Description: MRI/Ultrasound fusion saturation biopsy: the core number and location are designed according to the lession condition.
Study: NCT06257745

Intervention type: OTHER
Intervention: Compliance with ERACS guideline as described in the current ERACS guidelines from Engelman et al. 2019
Description: Compliance with the interventions as proposed in the ERACS guidelines and described in our previous publication (https://doi.org/10.1016/j.jtcvs.2022.07.010
Study: NCT05457101

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AI-based biliopancreatic EUS navigation system
Description: The endoscopists in the experimental group will be assisted by EndoAngel, which can in real-time prompt standard stations and anatomical structures during EUS. The system is an non-invasive AI system .
Study: NCT05853484

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bimodal lifestyle program
Description: Participants will be subjected to two training periods of six weeks (or until transplantation) of a semi-supervised home-based bimodal lifestyle program. The bimodal lifestyle program consists of an exercise program combined with nutritional support. The exercise program comprises high intensity interval training and endurance training, combined with peripheral resistance training and breathing exercises
Study: NCT05289713

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: appendectomy
Description: Laparoscopic appendectomy is performed within 18 hours after randomization in the surgery group. Patients in the symptomatic treatment group are carefully monitored and the same intervention (laparoscopic appendectomy) is performed in case of treatment failure.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: appendectomy
Description: Laparoscopic appendectomy is performed within 18 hours after randomization in the surgery group. Patients in the symptomatic treatment group are carefully monitored and the same intervention (laparoscopic appendectomy) is performed in case of treatment failure.
Study: NCT05891990

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: immediate implant augmented with sticky tooth
Description: * Topical anesthesia will be administered using an infiltration technique.~* Atraumatic extraction will be done with the aid of periotome and Luxators.~* The extraction socket will be debrided to remove any residual debris or granulation tissue.~* Full-thickness midcrestal incision and vertical releasing incision on the distal side will be made, and a vertical releasing incision on the mesial side will be made if necessary. The extraction socket and the labial bone defect will be exposed by buccal and palatal flap reflection.~* Implant insertion will be performed according to the manufacturer's instruction, and then the implant will be inserted 2mm apical to the alveolar bone crest with adequate primary stability.~* The gap between the implant and the defect of the facial bone will be filled with the sticky tooth to reach enough buccal bone supported and then will be covered with absorbable barrier collagen membranes.~* Finally, the flap will be repositioned and sutured.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: immediate implant augmented with autogenous tooth graft
Description: * Topical anesthesia will be administered using an infiltration technique.~* Atraumatic extraction will be done with the aid of periotome and Luxators.~* The extraction socket will be debrided to remove any residual debris or granulation tissue.~* Full-thickness midcrestal incision and vertical releasing incision on the distal side will be made, and a vertical releasing incision on the mesial side will be made if necessary. The extraction socket and the labial bone defect will be exposed by buccal and palatal flap reflection.~* Implant insertion will be performed according to the manufacturer's instruction, and then the implant will be inserted 2mm apical to the alveolar bone crest with adequate primary stability.~* The gap between the implant and the defect of the facial bone will be filled with the autogenous demineralized dentin graft to reach enough buccal bone supported and then will be covered with collagen membranes.~* Finally, the flap will be repositioned and sutured.
Study: NCT06483113

Intervention type: DEVICE
Intervention: Delefilcon A spherical soft contact lenses
Description: Silicone hydrogel contact lenses prescribed for single use, daily disposable wear (less than 24 hours while awake) for the correction of ametropia (myopia or hyperopia)

Intervention type: DEVICE
Intervention: Delefilcon A toric soft contact lenses
Description: Silicone hydrogel contact lenses prescribed for single use, daily disposable wear (less than 24 hours while awake) for the correction of ametropia (myopia or hyperopia) with astigmatism

Intervention type: DEVICE
Intervention: Delefilcon A multifocal soft contact lenses
Description: Silicone hydrogel contact lenses prescribed for single use, daily disposable wear (less than 24 hours while awake) for the correction of ametropia (myopia or hyperopia) with presbyopia
Study: NCT05315726

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamometer
Description: Measurement of elbow/wrist spasticity

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle vibrations
Description: 1 session of 10 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle vibrations
Description: 3 times/week for 6 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo muscle vibration
Description: 3 times/week for 6 weeks
Study: NCT05502978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Blended education of Infant and Young Child Feeding
Description: Blended education is an intervention about IYCF consisting of 3 components: Education via WhatsApp group, counselling face to face, Consultation with nutritionist via WhatsApp call. In the intervention group, participants will get blended education about IYCF provided by trained cadres. Education via WhatsApp group. The implementation of this educational program was carried out for 3 meeting sessions, where previously trained cadres had distributed videos and digital booklets for IYCF material and opened a discussion session at the end of the meeting in WhatsApp group. Face to face Counselling (Home visit). The cadres conduct home visits every month when the participants have given birth until the child is 7 months old. Consultation with nutritionist via WhatsApp call. Consultations were carried out via WhatsApp calls about IYCF practice was for infants aged 1 month, 3 months, 6 and 7 months.
Study: NCT06342076

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block
Description: To prevent postoperative pain, the researchers applied a subcostal transversus abdominis plane block in addition to the posterior transversus abdominis plane block to a group of patients who underwent surgery with a midline incision due to major gynecological cancer.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block
Description: To prevent postoperative pain, the researchers applied a subcostal transversus abdominis plane block in addition to the posterior transversus abdominis plane block to a group of patients who underwent surgery with a midline incision due to major gynecological cancer.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients undergoing rectus sheat block and posterior transversus abdominis plane block
Description: To prevent postoperative pain, the researchers applied a rectus sheath block in addition to the posterior transversus abdominis plane block to a group of patients who were operated on through a midline incision due to major gynecological cancer.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients undergoing rectus sheat block and posterior transversus abdominis plane block
Description: To prevent postoperative pain, the researchers applied a rectus sheath block in addition to the posterior transversus abdominis plane block to a group of patients who were operated on through a midline incision due to major gynecological cancer.
Study: NCT04762056

Intervention type: OTHER
Intervention: Chelsea Critical Care Physical Assessment Tool
Description: Chelsea Critical Care Physical Assessment Tool is a bedside assessment tool firstly reported in 2013 to measure physical morbidity in the critical care population, consisting of 10 items (respiratory function, cough, moving within the bed, supine to sitting on the edge of bed, dynamic sitting, standing balance, sit to stand, transferring from bed to chair, stepping, and grip strength) rated on a 6-point scale from complete dependency (level=0) to independency (level=5). Therefore, the CPAx sum score ranges from 0 (worst condition) to 50 (best functioning/independence)
Study: NCT05008822

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imaginary Training Group
Description: After the baseline assessment, the participant will receive Motor Imaginary Program

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Task oriented Training Group
Description: After the baseline assessment, the participant will receive MRP and CIMT training
Study: NCT05733715

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab infusion
Description: 100 mg/ 4mL on Day 1 of each 3- or 6- week cycle (one 3 wk cycle; up to eight 6 wk cycles)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab infusion
Description: 100 mg/ 4mL on Day 1 of each 3- or 6- week cycle (one 3 wk cycle; up to eight 6 wk cycles)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib tablet
Description: 10mg and 4mg daily for 21 days
Study: NCT06346223

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness and psychoeducation
Description: The single-session mindfulness intervention includes a 90-minute group-based session containing different mindfulness practices, psychoeducation and group sharing activities in the single-session mindfulness intervention. A self-practice tool kit will be provided to the participants for home practice 20 minutes daily through an online platform and the participants will be told to develop the practice as a daily habit. All of the teaching contents will be closely related to dementia caregiving and delivered by a mindfulness teacher who has received 40 hours training in dementia caregiving. A weekly mindfulness practice reminder will be sent to the participants through SMS for 8 weeks. The caregivers will also be provided with access to a social media online platform for sharing their practice experience with their classmates online. The interventionist will address their difficulties and challenges via the platform to reinforce skill mastery.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychoeducation
Description: The caregivers in the control group will receive brief education on dementia with the same group size and of the same duration (90-minutes) as the sessions in the intervention arm. The nurse will deliver brief education (15 minutes) on dementia in the session, followed by group sharing and discussion on their daily caregiving experience. The caregivers in the control group will be provided with a toolkit with education materials about the common health problems of older adults and also be given access to a social media platform in which they can communicate and share their caregiving experiences with classmates.
Study: NCT06484933

Intervention type: BEHAVIORAL
Intervention: Focus groups of health professionals and users of primary care
Description: 2 phases of Focus Group will be organized :~* the participants of the first 4 Focus Groups will propose an operational definition of the notion of a professional team in primary care (validation by consensus based on the definitions in the literature)~* 12 subsequent Focus Groups will be organized in 12 primary care teams to describe the ways in which risks are managed in primary care
Study: NCT04909437

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mycobiotic
Description: 2 sachet/day, 21 days, oral

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 sachet/day, 21 days, oral
Study: NCT01819623

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-pharmacological therapy
Description: It consists of a weekly two-hour session. During the first hour yoga classes will taught by teacher, during second hour supervised cognitive training by a psychologist based on Memory Program designed by Memory Unit of Madrid
Study: NCT06497153

Intervention type: PROCEDURE
Intervention: lung ultrasound
Description: lung ultrasound repeated according to protocol during the stay in the paediatric intensive care unit
Study: NCT06280690

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SGM-101
Description: SGM-101 is cea-targeted fluorescent dye

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SGM-101
Description: SGM-101 is cea-targeted fluorescent dye
Study: NCT04338126

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: previously described

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: previously described
Study: NCT04926883

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: bulk-fill composite resin restorations
Description: bulk-fill composite resin restorations up to 5mm layer thickness

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: bulk-fill composite resin restorations
Description: bulk-fill composite resin restorations up to 5mm layer thickness
Study: NCT05436756

Intervention type: OTHER
Group type: OTHER
Intervention: Biological sampling and collection
Description: * Biological sampling and collection:~  * whole blood: 1 dry tube for IgG and IgM anti-leptospirosis serology (volume depending on the patient's weight)~ * urine: 1 bottle of 30ml~* Freezing of serum after centrifugation~* Storage~* Collection of clinico-biological data on a dedicated eCRF
Study: NCT04862702

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: mechanical instrumentation using rotary file system
Description: the mechanical preparation will be performed using rotary file system

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mechanical instrumentation using rotary file system
Description: the mechanical preparation will be performed using rotary file system
Study: NCT05990478

Intervention type: DIAGNOSTIC_TEST
Intervention: Contrast-Enhanced Mammography
Description: Participants will have pre- and post-treatment CEM of the affected breast

Intervention type: DIAGNOSTIC_TEST
Intervention: Breast MRI
Description: Pre- and post-NAT breast MRI will be performed for all participants
Study: NCT04908332

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kangaroo Baby Massage
Description: The Kangaroo Baby Massage is an intervention that arose from nursing practice in 1996. It is a therapy that does not require an incubator, fuses massage, kangaroo position and music. KBM is available on video

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Kangaroo Baby Massage
Description: The Kangaroo Baby Massage is an intervention that arose from nursing practice in 1996. It is a therapy that does not require an incubator, fuses massage, kangaroo position and music. KBM is available on video
Study: NCT05797558

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Unilateral adrenalectomy
Description: Minimally invasive surgery is performed via the lateral transperitoneal approach or the posterior retroperitoneal approach, with or without robotic assistance, according to the surgeon's preference.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Medical treatment (eplerenone)
Description: The initial dose of eplerenone is 25 mg twice daily. The dose will be increased by 50 mg every fourth week until systolic blood pressure of 140 mmHg and diastolic blood pressure of 90 mmHg or lower has been reached and biochemical control (plasma renin above the middle of the reference range, i.e \> \~20 mIU/L) is attained and/or hyperkalemia develops. The maximal dose of eplerenone is 300 mg twice daily.
Study: NCT05836805

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]XZP-3621
Description: Extemporaneously compounded oral suspension solution of \[14C\]XZP-3621 (400 mg/200 µCi)
Study: NCT05745805

Intervention type: DEVICE
Intervention: Simultaneous cortico-spinal magnetic resonance imaging, Serum
Description: Simultaneous cortico-spinal magnetic resonance imaging data were collected in a strong magnetic field and collected the serum of participants.

Intervention type: DEVICE
Intervention: Simultaneous cortico-spinal magnetic resonance imaging, Serum
Description: Simultaneous cortico-spinal magnetic resonance imaging data were collected in a strong magnetic field and collected the serum of participants.

Intervention type: DEVICE
Intervention: Simultaneous cortico-spinal magnetic resonance imaging, Serum
Description: Simultaneous cortico-spinal magnetic resonance imaging data were collected in a strong magnetic field and collected the serum of participants.
Study: NCT05299047

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group US-guided
Description: An ultrasound system with a 5-2 MHz curved transducer will be used. The division of the abdominal aorta into the common iliac arteries was located using oblique sonography. Then, the transducer will image the body of the fifth lumbar vertebra, at which level bilateral common iliac vessels will be seen leaving a space in the midline. a 20 cm long, 22 gauge Chiba needle will be introduced into the hypogastrium, with out-of-plane technique to access the fifth lumbar vertebral body at its anterior-most point, so that injected drug spreads equally bilaterally along the anterior curvature of the fifth lumbar vertebral body.Suction was applied to the needle to confirm that it was not within a vessel and 10 ml of 50% ethanol will be injected for neurolysis.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group fluoroscopy-guided
Description: The patient will be placed in the supine position. The L5-S1 inter-discal space was identified under fluoroscopy.After providing local cutaneous and subcutaneous anesthesia with 2% Lignocaine solution nearly 3-4 cm below the umbilicus, a 20 cm long, 22 gauges Chiba needle is advanced to the anterior portion of the 5th vertebral body under ongoing fluoroscopic guidance. Once bony resistance is reached, gently inject 2-5 ml contrast which typical reveals a characteristic triangular blob of contrast with no vascular opacification.Before injection the needle is aspirated to confirm there is no blood. A preliminary test dose of about 3 cc of 0.5% bupivacaine is then injected. If there is no change in heart rate or neurological status, rest of the 20 cc phenol 10% is injected slowly with intermittent aspiration.