TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06506435

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Two Dimensional (2D) Informational Video
Description: A 30-minute informational video. The two dimensional (2D) video provides information about the radiotherapy process. Participants will receive this one-time intervention in-person, prior to treatment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: First-Person Virtual Reality Video
Description: A 30-minute virtual reality video, experienced through a headset, provides an immersive portrayal of the radiotherapy process from a first-person perspective. Participants will receive this one-time intervention in-person, prior to treatment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Third-Person Virtual Reality Video
Description: A 30-minute virtual reality video, experienced through a headset, provides an immersive portrayal of the radiotherapy process from a third-person perspective. Participants will receive this one-time intervention in-person, prior to treatment.
Study: NCT06574815

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Early implant loading
Description: Patients underwent definitive restoration at 6 weeks after implant surgery (early loading).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Early implant loading
Description: Patients underwent definitive restoration at 6 weeks after implant surgery (early loading).

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Delayed implant loading
Description: Patients underwent definitive restoration at 6 months after implant surgery (delayed loading).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: GBR using an SIS membrane
Description: An small intestine submucosa (SIS) membrane was used in the guided bone regeneration (GBR) surgery.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: GBR using an Bio-Gide membrane
Description: An Bio-Gide membrane was used in the guided bone regeneration (GBR) surgery.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: GBR using an Bio-Gide membrane
Description: An Bio-Gide membrane was used in the guided bone regeneration (GBR) surgery.
Study: NCT05711641

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine 10 MG/ML
Description: Application of 10% topical lidocaine in the external auditory canal of tinnitus patients.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Distilled water
Description: Application of distilled water in the external auditory canal of tinnitus patients.
Study: NCT04576091

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT and/or PET-CT scan

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elimusertib
Description: Given PO

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET-CT scan

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiation Therapy
Description: Undergo SBRT
Study: NCT05051761

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Jaktinib
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Jaktinib
Description: Administered orally.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Administered orally.
Study: NCT05138419

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CKD What You Need To Know Workbook System
Description: 139 page Workbook including CKD Action Plan, Web-Based Resources, Interactive CKD Patient education material

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CKD What You Need To Know Workbook System
Description: 139 page Workbook including CKD Action Plan, Web-Based Resources, Interactive CKD Patient education material

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CKD Action Plan
Description: Goals based on international guidelines that can protect kidney function (1 knowledge and 10 action goals) Patient education material used separately for control arm.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: CKD Action Plan
Description: Goals based on international guidelines that can protect kidney function (1 knowledge and 10 action goals) Patient education material used separately for control arm.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CKD Action Plan
Description: Goals based on international guidelines that can protect kidney function (1 knowledge and 10 action goals) Patient education material used separately for control arm.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CKD Web-based Resource List
Description: CKD Patient education material used separately for control arm

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: CKD Web-based Resource List
Description: CKD Patient education material used separately for control arm

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CKD Web-based Resource List
Description: CKD Patient education material used separately for control arm

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Food Label reading exercise
Description: CKD Patient education material used separately in all arms.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Food Label reading exercise
Description: CKD Patient education material used separately in all arms.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Food Label reading exercise
Description: CKD Patient education material used separately in all arms.
Study: NCT06453265

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cebranopadol- 600 ug
Description: Dose ascending cohorts~- Cebranopadol 600 ug single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cebranopadol- 800ug
Description: Dose ascending cohorts~- Cebraopadol 800 ug single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cebranopadol- 1000ug
Description: Dose ascending cohorts~- Cebranopadol 1000 ug single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment A:
Description: Cebranopadol, dose determined in Part A

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Treatment B
Description: Oxycodone HCl IR 40 mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Treatment C
Description: Placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Qualification
Description: Oxycodone 40mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Qualification
Description: Matching Placebo
Study: NCT06338982

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Interoperative wisdom tooth removal in conjunction with BSSO
Description: The objective of the present randomized controlled trial is to assess the fracture pattern, condylar segment positioning, frequency of complications, and PROMs following BSSO with or without impacted mandibular third molars. this is illustrated by the fact that the test group had their wisdom teeth removed in connection with the sagittal split of the mandible (the BSSO surgery). Subsequently, all outcome measures are compared with the control group, who had their wisdom teeth removed 6 months prior their BSSO surgery.
Study: NCT06579599

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: an integrated working group nursing
Description: (1) Establishment of an integrated team in the operating room; (2) Development of a nursing plan; (3) Nursing safety training and reflection in the operating room; (4) Designate a person to manage instruments and equipment in the operating room and establish protocols (5) Nurses should also participate in the development of the patient's individualized surgical plan communicate with the surgeon about the preparation of items needed for surgery to ensure seamless coordination. Assist anesthesiologists and surgeons and oversee the implementation of aseptic procedures.
Study: NCT05850832

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Esmolol
Description: loading dose 1 mg/kg followed by maintenance dose of 30 μg/kg/min throughout the surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium sulfate
Description: loading dose 40 mg/kg over a period of 15 mins and maintenance 15 mg/kg/h throughout the surgery.
Study: NCT04674241

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Ten minutes after anesthesia induction and endotracheal intubation, patients assigned to dexmedetomidine group were given a loading dose of dexmedetomidine 0.6 μg/kg over 10 minutes, followed by continuous infusion at a rate of 0.4 μg/kg/h until the start of dural closure.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% saline
Description: 0.9% saline is administered with the same volume at the same speed as the other group.
Study: NCT04715568

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan
Description: 50 mg tablets taken orally
Study: NCT05497037

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: Sham stimulation for 15 min
Study: NCT03487627

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Electronic and Care Support Manager Contact
Description: This intervention will consist of electronic and Care Support Manager (CSM) contacts with parents from the first week following their adolescent's discharge from hospitalization through the first 3 months after discharge. The electronic application content will be accessible and delivered to parents weekly. Parents will also be able to enter a keyword on their electronic device to access content and material in real time. The CSM contacts will supplement the informational content delivered electronically by providing opportunities to ask questions about the electronic application material, and by checking on progress toward treatment follow through for their youth, identifying and problem solving any difficulties and concerns, and addressing health needs of each parent.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Treatment-as-usual (TAU)
Description: TAU typically involves a discharge planning session by unit staff with the adolescent and their parent(s) to discuss safety monitoring and referrals for mental health services following discharge from psychiatric hospitalization. Investigators will augment this usual care by providing written materials to families outlining some of the key considerations for caring for their adolescent. These written materials will include brochures with information for parents following adolescent suicidal behavior, a listing of resources including instructions for when to call 911 or go to the emergency room, and information regarding the National Suicide Prevention Lifeline. Written materials will be provided to both the enhanced TAU participants as well as participants receiving the electronic and CSM intervention.
Study: NCT04715568

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Tablets taken orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Tablets taken orally
Study: NCT05047120

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hypnosis enhanced cognitive behavioral therapy
Description: This therapy entails subjects being induced into a state of relaxation and the receiving cognitive behavioral therapy for pain associated with a new spinal cord injury.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Education
Description: This therapy entails subjects learning about the causes, mechanisms, and ways to reduce pain associated with a new spinal cord injury.
Study: NCT05330819

Intervention type: OTHER
Intervention: Non-interventional
Description: Blood thrombogenicity in patients with previous history of myocardial infarction will be studied using Badimon perfusion chamber, SEM and TEG.

Intervention type: OTHER
Intervention: Non-interventional
Description: Blood thrombogenicity in patients with previous history of myocardial infarction will be studied using Badimon perfusion chamber, SEM and TEG.
Study: NCT05773768

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EHRA-PATHS software tool
Description: Newly developed care pathways integrated into a care-management software tool
Study: NCT04737460

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: AAV9/CLN7
Description: Enrollees will receive gene therapy via a viral vector
Study: NCT05244226

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl/Hydromorphone
Description: Per routine care

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methadone
Description: Initial dosing 0.1mg/kg, potential to escalate to 0.15mg/kg following interim analysis
Study: NCT06091982

Intervention type: PROCEDURE
Intervention: Renal Replacement Therapy (RRT)
Description: Renal Support therapy which consist of procedure of intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration/hemodialysis/hemodiafiltration (CVVH/CVVHD/CVVHDF)
Study: NCT05608408

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Frequency Stimulation (LFS) of site with the Medtronic Percept PC system
Description: Stimulation of site with the Medtronic Percept PC system using low frequency stimulation at 0.5 Hz.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Frequency Stimulation (LFS) of site with the Medtronic Percept PC system
Description: Stimulation of site with the Medtronic Percept PC system using low frequency stimulation at 0.5 Hz.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Frequency Stimulation (LFS) of site with the Medtronic Percept PC system
Description: Stimulation of site with the Medtronic Percept PC system using low frequency stimulation at 0.5 Hz.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Frequency Stimulation (LFS) of site with the Medtronic Percept PC system
Description: Stimulation of site with the Medtronic Percept PC system using low frequency stimulation at 0.5 Hz.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC) High Frequency Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system
Description: Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system using standard of care high frequency stimulation parameters.
Study: NCT05427461

Intervention type: OTHER
Group type: OTHER
Intervention: Blood samples will be collected at different times.
Description: For patients with localized leiomyosarcoma, samples will be collected:~* At Baseline.~* Before surgery (for patients who have had neoadjuvant treatment (external radiotherapy and/or chemotherapy)).~* After surgery.~* At each control visit.~* At local or metastatic recurrence (or at 24 months post inclusion if no progression).~For patients with metastatic leiomyosarcoma, samples will be collected:~* At Baseline.~* At each therapeutic line.~* At progression (or at 24 months post inclusion if no progression).
Study: NCT05351801

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: THC (Syndros)
Description: Participants will receive a target dose of 10mg per day of THC (Syndros).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CBD (Epidolex)
Description: Participants will receive a target dose of 800 mg per day of CBD (Epidolex).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: THC + CBD (Nabiximols)
Description: Participants will receive a target dose of 10.8 mg / 10 mg per day of THC + CBD (Nabiximols).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05608408

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC) High Frequency Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system
Description: Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system using standard of care high frequency stimulation parameters.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC) High Frequency Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system
Description: Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system using standard of care high frequency stimulation parameters.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC) High Frequency Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system
Description: Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system using standard of care high frequency stimulation parameters.
Study: NCT06065202

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutrition Supplement
Description: Total parenteral nutrition (TPN) will be administered within 72 hours of abdominal surgery. Nutritional shakes will be started with a liquid diet and given 3 times a day. This will continue for 4 weeks after discharge.
Study: NCT05842915

Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Baseline and 3 month questionnaire
Study: NCT05256589

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sona Saliva C-19 Rapid Self-test
Description: Rapid Antigen diagnostic device performance comparative to RT-PCR
Study: NCT06358339

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.
Study: NCT06351566

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: Vitamin D3 (cholecalciferol), 1600 IU per day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: Vitamin D3 (cholecalciferol), 1600 IU per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotics
Description: Prebiotics (inulin), 10g per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotics
Description: Prebiotics (inulin), 10g per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3 placebo
Description: Vitamin D3 placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Vitamin D3 placebo
Description: Vitamin D3 placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotics placebo
Description: Prebiotics placebo, 10g per day.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Prebiotics placebo
Description: Prebiotics placebo, 10g per day.
Study: NCT06358339

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.
Study: NCT06057142

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fun activities for reciting Tang poems
Description: The students will participate in three weekly sessions of Tang poem classes and one session of performance show. Each session lasts for 1.5 hours. Parents can sit in the class. A total of six poems will be taught by two experienced Chinese teachers.
Study: NCT04070924

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bandaid
Description: Bandaid dressing

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional bulky soft tissue dressing
Description: Conventional bulky soft tissue dressing
Study: NCT04776980

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Post Feraheme Infusion MRI
Description: All participants will receive a ferumoxtyol (Feraheme) infusion 20-28 hours prior to a head MRI. In addition, a blood draw for liquid biopsy targeted tissue sampling during surgery and special iron and macrophage staining on the tumor tissue.