TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05161624

Intervention type: DIAGNOSTIC_TEST
Intervention: Accuracy evaluation
Description: The design of the diagnostic trial will include 160 cases of liver tumors with indications for microwave ablation after a multidisciplinary consultation with clinicians (Multiple Disciplinary Team, MDT), including primary liver cancer and metastatic liver tumors, and the tumor diameter is less than 3 cm. The test subjects consist of three groups: a. path planning model, b. junior ablation specialists, c. senior ablation specialists. The three groups will perform microwave ablation path planning on 160 selected cases of liver tumors. The attending professor of the clinical medical group of the department is responsible for scoring, evaluating whether the design of the plan is reasonable, and then comparing the scoring results by using statistical methods to evaluate the accuracy and effectiveness of the path planning model established in this study.
Study: NCT05626465

Intervention type: OTHER
Intervention: Blood test
Description: Proteomic analyses on serum

Intervention type: OTHER
Intervention: Blood test
Description: Proteomic analyses on serum

Intervention type: OTHER
Intervention: Blood test
Description: Proteomic analyses on serum

Intervention type: OTHER
Intervention: Blood test
Description: Proteomic analyses on serum
Study: NCT05963165

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Non-phonatory exercises
Description: Muscle exercises that favor glottic adduction without vocal emissions
Study: NCT05847556

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: video game hearing tests
Description: Video game hearing tests (as a non-medical device) used to monitor ototoxicity

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audio-training
Description: Audio-training (as a non-medical device) used to determine if it can improve spatial hearing perception.
Study: NCT06304051

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intermittent Oro-esophageal Tube Feeding
Description: Before each feeding, inside and outside of the tube was cleaned with water. During feeding, the patient should maintain a semi-reclining or sitting position with mouth opened, and the tube was inserted slowly and smoothly into the upper part of the esophagus by medical staffs while the appropriate depth of intubation was checked with the calibration markings on the tube wall. The distance from the incisors to the head part of the tube should be between 22-25 cm. However, the specific depth should be evaluated based on patients' feedback and adjusted accordingly. After insertion, the tail part of the tube should be put into a container full of water and the absence of continuous bubbles indicated a successful intubation. Then, the feeding was to be conducted three times per day with 50 ml per minute and 400-600ml for each feeding.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric Tube Feeding
Description: Within 4 hours after admission, the placement of the feeding tube was conducted by professional medical staffs and after intubation, the tube was secured to the patient's cheek with medical tape. The feeding was conducted once every 3-4 hours, with 200-300ml each time. The total feeding volume was determined based on daily requirements. The feeding content was formulated by the nutritionists based on the patient\&#39;s condition and relevant guidelines to reach the energy demand as 20-25 kcal/kg/day and protein supplementation of 1.2-2.0 g/kg/day for both two groups. For patients with limited tube feeding compliance, the investigators made appropriate adjustments to ensure that they were not at risk of severe malnutrition as much as possible.
Study: NCT05535959

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-121/TEZ/D-IVA
Description: FDC tablet for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-121/TEZ/D-IVA
Description: FDC tablet for oral administration.
Study: NCT06121934

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carica Papaya Leaf Extract
Description: Active drug: CPLE 500mg 2 capsule t.i.d for 5 dayseive CPLE or placebo once daily for 5 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo: visually matched placebo 2 capsule t.i.d for 5 days
Study: NCT05042895

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group A
Description: Office diagnostic hysteroscopy for assessment of the following:~* cervical canal: arborvitae, mucous, any abnormal pathology like a polyp.~* Endometrium cavity: vascularity, thickness, color, gland openings, any abnormal pathology.~* Darwishhysterscopic triad: shape, caliber, depth, abnormal pathology, flow patency, bubble flow patency, and peristalsis.~Endometrial sample by a Novak's curette Histopathologic assessment: will be sent for the routine out-patient Pathology lab to comment on the endometrial pattern and abnormalities.~Physical and laboratory examinations follicle-stimulating hormone \[FSH\], LH, thyroid-stimulating hormone \[TSH\], prolactin, and pre ovulatory LH LH levels of the patients will be measured on day 3 of the menstrual cycle.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group B
Description: Office diagnostic hysteroscopy for assessment of the following:~* cervical canal: arborvitae, mucous, any abnormal pathology like a polyp.~* Endometrium cavity: vascularity, thickness, color, gland openings, any abnormal pathology.~* Darwishhysterscopic triad: shape, caliber, depth, abnormal pathology, flow patency, bubble flow patency, and peristalsis.~Endometrial sample by a Novak's curette Histopathologic assessment: will be sent for the routine out-patient Pathology lab to comment on the endometrial pattern and abnormalities.~Physical and laboratory examinations follicle-stimulating hormone \[FSH\], LH, thyroid-stimulating hormone \[TSH\], prolactin, and pre ovulatory LH LH levels of the patients will be measured on day 3 of the menstrual cycle.
Study: NCT05582824

Intervention type: OTHER
Intervention: Blood and urine test
Description: Daily blood and urine samples
Study: NCT06140875

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radiofrequency electromagnetic field treatment
Description: Radiofrequency electromagnetic field treatment using a carrier frequency of 13.56 MHz
Study: NCT05615857

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of Endocuff during colonoscopy
Description: We will be adding the Endocuff device to the proximal end of the colonoscope, adding an additional tool to facilitate the visualization of the difficult-to-see mucosal areas as well as the rectum. There will be no need for retroflexion to evaluate the colon
Study: NCT05701059

Intervention type: PROCEDURE
Intervention: Cervical arthroplasty
Description: A joint replacement procedure administered by inserting an artificial disc between the vertebrae to replace a natural spinal disc after it has been removed.

Intervention type: PROCEDURE
Intervention: Cervical arthroplasty
Description: A joint replacement procedure administered by inserting an artificial disc between the vertebrae to replace a natural spinal disc after it has been removed.

Intervention type: DEVICE
Intervention: Semi-Constrained Nuvasive Simplify
Description: This weight-bearing implant consisting of PEEK (polyetheretherketone) endplates and one semi-constrained, fully articulating, mobile zirconia toughened alumina (ZTA) ceramic core will be administered by cervical arthroplasty into the specified single-level cervical region.
Study: NCT05006651

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: McGrath MAC
Description: Intubaion with McGrath MAC

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Trachway
Description: Intubaion with Trachway
Study: NCT05001386

Intervention type: BIOLOGICAL
Group type: SHAM_COMPARATOR
Intervention: Blood collection for the evaluation of the anti-drugs sensitivity
Description: The M.D investigators and the medical team identify the patients ( index cases and healthy volunteers) in a medical appointment. They inform them, collect the non-opposition right and the blood samples: 5 mL heparin tube and 5 mL dry tube for each person , one time.
Study: NCT05075434

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Treatment
Description: This protocol will be the one prescribed by the health centre. It consists of calf stretching exercises, plantar fascia, proprioceptive exercises, ultrasound, magnetic therapy and gait re-education and proprioceptive exercises for 40-45 minutes. Participants will receive 8 treatment sessions spread over 4 weeks (2 sessions per week).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Treatment
Description: This protocol will be the one prescribed by the health centre. It consists of calf stretching exercises, plantar fascia, proprioceptive exercises, ultrasound, magnetic therapy and gait re-education and proprioceptive exercises for 40-45 minutes. Participants will receive 8 treatment sessions spread over 4 weeks (2 sessions per week).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diacutaneous fibrolysis
Description: 15 minutes of the treatment technique. The FD intervention will be carried out with the same duration and protocol for all participants.~The intervention protocol will be: Start with the point of maximum tension between the two muscle bellies of the calf and hamstring (reverse hook). Then work on the peroneus longus lateralis and soleus. Then the external calf muscle belly and soleus and the internal calf muscle belly and soleus. Then work on the tendon of the flexor hallucis proprio of the big toe and the inner edge of the Achilles tendon and peroneus longus. Then treatment of the peroneus longus with the peroneus brevis. Scraping of the insertion of the Achilles tendon, hooking of the internal and external part of the plantar fascia. Finally, longitudinal friction of the plantar fascia.
Study: NCT04585633

Intervention type: OTHER
Intervention: Quality of Recovery-15
Description: Quality of Recovery-15 is a scale consisting of 15 questions indicating the recovery quality of the patient after anesthesia and a score between 0-150.

Intervention type: OTHER
Intervention: Quality of Recovery-15
Description: Quality of Recovery-15 is a scale consisting of 15 questions indicating the recovery quality of the patient after anesthesia and a score between 0-150.

Intervention type: OTHER
Intervention: Glasgow Result Scale
Description: Glasgow Outcome Scale; It is a scale developed to categorize people suffering from head trauma or non-traumatic acute brain injury into broad outcome categories. It shows postoperative mortality and morbidity of patients who underwent intracranial surgery.

Intervention type: OTHER
Intervention: Glasgow Result Scale
Description: Glasgow Outcome Scale; It is a scale developed to categorize people suffering from head trauma or non-traumatic acute brain injury into broad outcome categories. It shows postoperative mortality and morbidity of patients who underwent intracranial surgery.

Intervention type: OTHER
Intervention: Risk Factors
Description: Pre-operative: medical histories, drugs used, demographic features, additional diseases, ASA class, pre-operative routine parameters, operation history, GCS, tumor histology, location, dimensions and intracerebral radiological data, laboratory values Intraoperative; hemodynamic data of patients; highest and lowest values of heart rate, diastolic, systolic and mean arterial pressures, fluid and blood products given, anesthetic and other drugs administered, duration of anesthesia, duration of surgery, surgical position, blood loss, urine output and blood gas samples Post-operation; extubation time, MAS score, use of mechanical ventilation, post-operative complications, hemodynamic data, blood gas data

Intervention type: OTHER
Intervention: Risk Factors
Description: Pre-operative: medical histories, drugs used, demographic features, additional diseases, ASA class, pre-operative routine parameters, operation history, GCS, tumor histology, location, dimensions and intracerebral radiological data, laboratory values Intraoperative; hemodynamic data of patients; highest and lowest values of heart rate, diastolic, systolic and mean arterial pressures, fluid and blood products given, anesthetic and other drugs administered, duration of anesthesia, duration of surgery, surgical position, blood loss, urine output and blood gas samples Post-operation; extubation time, MAS score, use of mechanical ventilation, post-operative complications, hemodynamic data, blood gas data
Study: NCT04995666

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Phonak Audeo hearing aid
Description: Rechargeable hearing aid
Study: NCT05027711

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: ITV (Internal target volume)-based Stereotactic Body Radiotherapy (ITV-SBRT)
Description: ITV (Internal target volume)-based Stereotactic Body Radiotherapy (ITV-SBRT)

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MRgSBRT (Magnetic Resonance-guided Stereotactic Body Radiotherapy)
Description: MRgSBRT (Magnetic Resonance-guided Stereotactic Body Radiotherapy)

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MRgSBRT (Magnetic Resonance-guided Stereotactic Body Radiotherapy)
Description: MRgSBRT (Magnetic Resonance-guided Stereotactic Body Radiotherapy)
Study: NCT06378164

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: For the combined step training group, the participants will receive training on both volitional and reactive stepping. The training will last for 1 hours per session, 2 session per week for 4 weeks.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Active Control
Description: An active control group will be used to minimise the placebo and history effect. The group will also receive a 4-week programme with the frequency and duration of the training and the instructor-to-participant ratio that match the combined step training group. During training, they will perform exercises not specific to reducing fall risk.
Study: NCT06052111

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group F (fentanyl group)
Description: Fentanyl (1 μg/kg) was given intravenously slowly over 60 seconds before induction of anesthesia as loading dose followed by continuous infusion at a rate of (1μg/kg/hr) after intubation and was stopped 10 minutes before the end of surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group D (dexmedetomidine group)
Description: The patients received loading dose of dexmedetomidine (1 μg/kg) (Precedex, Abbot Laboratories Inc., Abbot Park, IL, USA) intravenously over 15 minutes before induction of anesthesia followed by continuous infusion at a rate of (0.6 μg/ kg/ hr) after intubation and was stopped 10 minutes before the end of surgery.
Study: NCT05735366

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAIL66
Description: SAIL66 as a IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAIL66
Description: SAIL66 as a IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAIL66
Description: SAIL66 as a IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Obinutuzumab as an IV infusion
Study: NCT06060158

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy for Insomnia
Description: 6 sessions
Study: NCT06161233

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CAPABLE cohort
Description: The CAPABLE cohort receives the mobileapplication and a multi-sensorial smartwatch (ASUS VivoWatch 5 HC-B05). Patients will be asked to use the system for at least 6 months. The CAPABLE app serves three main functionalities for the patient: symptom monitoring, information needs fulfilment and interventions to improve mental- and physical wellbeing
Study: NCT05610670

Intervention type: OTHER
Group type: OTHER
Intervention: Questionnaire
Description: The questionnaire will allow us to complete the information and to collect their experiences regarding the desire and/or achievement of a pregnancy, but also their gynecological follow-up in the broad sense, on the other hand.
Study: NCT05467033

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Desmopressin
Description: desmopressin 0,3ug/kg in 100ml 0,9% NaCl managed as intravenous infusion;

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intravenous infusion NaCl
Description: 0,9% NaCl managed as intravenous infusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: intravenous infusion NaCl
Description: 0,9% NaCl managed as intravenous infusion
Study: NCT04293900

Intervention type: OTHER
Intervention: 24-hour dietary recall
Description: Dietary intake assessment conducted by a Registered Dietitian Nutritionist. This assessment will occur prior to starting R-CHOP chemotherapy, during the clinic visits for each round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.

Intervention type: OTHER
Intervention: Hand grip strength
Description: Measurement of grip strength using a hand dynamometer. This will test occur prior to starting R-CHOP chemotherapy, during the clinic visits for each round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.
Study: NCT05441436

Intervention type: PROCEDURE
Intervention: Allogeneic hematopoietic stem cell transplantation
Description: Allogeneic hematopoietic stem cell transplantation

Intervention type: PROCEDURE
Intervention: Solid organ transplantation
Description: Solid organ transplantation
Study: NCT05926895

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Injection of 1 CC Betamethasone Dipropionate + Betamethasone Sodium Phosphate (Diprospan) and 4 cc 2% Prilocaine (Priloc)mixture into the subacromial space
Description: Treatment method used in the treatment of subacromial impingement syndrome

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Injection of 1 CC Betamethasone Dipropionate + Betamethasone Sodium Phosphate (Diprospan) and 4 cc 2% Prilocaine (Priloc)mixture into the subacromial space
Description: Treatment method used in the treatment of subacromial impingement syndrome
Study: NCT04293900

Intervention type: OTHER
Intervention: International Physical Activity Questionnaire
Description: Survey about physical activity over the previous 7 days. This survey will be administered prior to starting R-CHOP chemotherapy, during the clinic visits for each round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.

Intervention type: OTHER
Intervention: Patient-reported outcomes survey
Description: Survey about symptoms and side effects experienced during cancer treatment. This will be administered prior to starting R-CHOP chemotherapy, during the clinic visits for each round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.

Intervention type: OTHER
Intervention: Pittsburgh Sleep Quality Index
Description: Survey about sleep habits and quality over the past month. This will be administered prior to starting R-CHOP chemotherapy, during the clinic visits for each round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.

Intervention type: OTHER
Intervention: Functional Assessment of Cancer Treatment - Lymphoma
Description: Survey about quality of life for people with a diagnosis of lymphoma. This will be administered prior to starting R-CHOP chemotherapy, during the clinic visits for each round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.

Intervention type: OTHER
Intervention: urine sample (optional)
Description: Collect three urine samples either in the clinic or at home. This specimen collection will occur prior to starting R-CHOP chemotherapy, after the third round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.

Intervention type: OTHER
Intervention: fecal sample (optional)
Description: Collect a fecal sample either in the clinic or at home. This sample collection will occur prior to starting R-CHOP chemotherapy, after the third round of R-CHOP chemotherapy, and again at the end of the scheduled course of R-CHOP chemotherapy.
Study: NCT06093438

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Patients enrolled in this arm would receive three cycles of induction treatment before receiving definitive chemoradiotherapy. The specific regimen is: Paclitaxel(135mg/m2,ivd, d1)+cisplatin(75mg/m2,ivd,d1-3)+Toripalimab (240mg,ivd,d1)±bevacizumab(ivd, d1)/q21d. Patients would receive pelvic MRI to evaluate the regression status of tumor after three cycles of induction treatment. Patients with satisfying tumor regression would receive definitive chemoradiotherapy afterwards. During chemoradiotherapy, patients would receive weekly cisplatin (40mg/m2) and 240mg toripalimab every three weeks. After chemoradiotherapy, patients would receive another three cycles of consolidated treatment (regimen identical to induction treatment).
Study: NCT05001386

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood collection for the evaluation of the anti-drugs sensitivity
Description: The M.D investigators and the medical team identify the patients ( index cases and healthy volunteers) in a medical appointment. They inform them, collect the non-opposition right and the blood samples: 5 mL heparin tube and 5 mL dry tube for each person , one time.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood collection for the evaluation of the anti-drugs sensitivity
Description: The M.D investigators and the medical team identify the patients ( index cases and healthy volunteers) in a medical appointment. They inform them, collect the non-opposition right and the blood samples: 5 mL heparin tube and 5 mL dry tube for each person , one time.
Study: NCT06208891

Intervention type: PROCEDURE
Intervention: Robotic myomectomy
Description: Robotic assisted laparoscopic myomectomy
Study: NCT05701059

Intervention type: DEVICE
Intervention: Unconstrained Biomet Zimmer Mobi-C
Description: This unconstrained, three-piece implant will be administered by cervical arthroplasty into the specified single-level cervical region.
Study: NCT05114993

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wearing a disposable surgical mask
Description: Physiologic vital signs will be monitored every minute for 5 minutes without a mask, followed by every minute for 15 minutes with a surgical mask.
Study: NCT05563571

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylprednisolon, Lidocaine
Description: Intra-articular cortisone injection

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pulsed radiofrequency, Lidocaine
Description: pulsed radiofrequency of shoulder joint and suprascapular nerve
Study: NCT06193733

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Dendritic Cell
Description: Biological: Immunotherapy with dendritic cells