TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05818397

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Compassion for Children and Caregivers (SCCC)
Description: A standardized, manualized adaptation of the mindful self-compassion curriculum for adults, designed for online delivery. Dyads join a group video conference call along with other caregiver-child dyads and and up to two experienced SCCC facilitators. Sessions occur 1-hour per week for 6 weeks at a time convenient for the group.
Study: NCT05329389

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: StoneMD
Description: StoneMD - is an app from App Store (for iOS) or Google Play (for Android).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: StoneMD
Description: StoneMD - is an app from App Store (for iOS) or Google Play (for Android).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Schools of Patients
Description: The Schools for Patients with Urolithiasis is an online course for patients with urinary stone disease.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard recommendation
Description: Only fluid balance recommendations given at the day of discharge.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard recommendation
Description: Only fluid balance recommendations given at the day of discharge.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard recommendation
Description: Only fluid balance recommendations given at the day of discharge.
Study: NCT05525975

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational materials
Description: Educational materials will be developed by our interdisciplinary research team. Will consist of a brochure and a video. Both materials highlight important information about opioid medications, explain proper disposal of excess of opioid medications and provide drug-free pain management tools for postoperative pain.
Study: NCT04572854

Intervention type: DRUG
Group type: OTHER
Intervention: Pegcetacoplan
Description: Complement (C3) Inhibitor
Study: NCT04915339

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: The intervention is administrated through a computerized application as prescribed exercises (cognitive or physical). The specific measures that will be used to determine the effect of the intervention are psychological variables (mood, anxiety, well-being, cognitive variables...) and physical ones (Heart rate variability, stress biomarkers, fat and muscle mass, blood circulation...).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: The intervention is administrated through a computerized application as prescribed exercises (cognitive or physical). The specific measures that will be used to determine the effect of the intervention are psychological variables (mood, anxiety, well-being, cognitive variables...) and physical ones (Heart rate variability, stress biomarkers, fat and muscle mass, blood circulation...).
Study: NCT05812755

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vericiguat
Description: Vericiguat 10 mg administered orally starting 2 days prior to heart surgery through the day of surgery

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo administered orally starting 2 days prior to heart surgery through the day of surgery
Study: NCT04915339

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive training
Description: The intervention is administrated through a computerized application as prescribed exercises (cognitive or physical). The specific measures that will be used to determine the effect of the intervention are psychological variables (mood, anxiety, well-being, cognitive variables...) and physical ones (Heart rate variability, stress biomarkers, fat and muscle mass, blood circulation...).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive training
Description: The intervention is administrated through a computerized application as prescribed exercises (cognitive or physical). The specific measures that will be used to determine the effect of the intervention are psychological variables (mood, anxiety, well-being, cognitive variables...) and physical ones (Heart rate variability, stress biomarkers, fat and muscle mass, blood circulation...).
Study: NCT05168592

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Threat conditioning
Description: Day 1: The participant is repeatedly shown two stimulus (CS+,CS-), one at a time. CS+ is paired with an electric shock. CS- acts as a control stimulus. The stimuli consist of photos of two different objects. Stimuli will be counterbalanced between participants.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Imaginal extinction
Description: Day 1: Participants are repeatedly instructed to produce mental imagery of the two stimuli used during threat conditioning. Imagery is prompted through different written instructions presented in pseudo-randomized order on a screen. No shocks will be delivered.
Study: NCT04915339

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: combined physical and cognitive training
Description: The intervention is administrated through a computerized application as prescribed exercises (cognitive or physical). The specific measures that will be used to determine the effect of the intervention are psychological variables (mood, anxiety, well-being, cognitive variables...) and physical ones (Heart rate variability, stress biomarkers, fat and muscle mass, blood circulation...).
Study: NCT05148767

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant chemoradiotherapy based on irinotecan
Description: Patients with locally advanced rectal cancer treated with irinotecan-based chemoradiotherapy were enrolled in this study. The dose of irinotecan is determined by the genotype of UGT1A1.Concurrent Chemoradiotherapy:~Radiation: 50Gy/25Fx; Capecitabine: 625mg/m2 bid Monday-Friday per week; Irinotecan: 80mg/m2 (UGT1A1\*28 and \*6: 6/6+GG) or 65mg/m2 (UGT1A1\*28 and \*6 ：6/7+GG or 6/6+GA) or 50mg/m2 （UGT1A1\*28 and \*6 ：7/7+GG or 6/6+AA or 6/7+GA）.
Study: NCT04789330

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: Norepinephrine administered during anesthesia

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phenylephrine
Description: Phenylephrine administered during anesthesia
Study: NCT06220266

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phytoestrogen
Description: consume 1 capsule twice a day for 2 months which one capsule composed of dry weight 50 mg of Pueraria Mirifica 1or Pueraria Mirifica 2 or Pueraria Mirifica 3

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Diet control & life style modification
Description: Diet control \& life style modification
Study: NCT05126446

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: the Aorta Arch Stent Graft System combined with the Endovascular Needle System
Description: Patients who meet all the inclusion criteria and don't meet the exclusion criteria will be implanted with device
Study: NCT06286787

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention
Description: The training programme will consist of a 3-hour lecture. The contents of the lecture will include knowledge of mountaineering in Hong Kong, country codes and care for the environment, environmental awareness when undertaking outdoor activities, hiking skills, knowledge and choice of hiking equipment and clothing, trip planning, mountain safety, map reading, the use of a compass, mountain safety, basic first aid, methods of calling for help in an emergency and sources of weather data. After completing the lecture, participants will be required to join a 6-day hiking training programme on weekends within a 3-month period (each training will be at least 5 kilometres and the duration will be at least 4 hours).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Control participants will be asked to join six day-time leisure activities on weekends within a 3-month period. Leisure activities will be organised by the Asbury Methodist Social Service and will include cartoon film shows, handicraft workshops, chess games, health talks on the prevention of influenza and eating a healthy diet, and day visits to a museum and theme park. Children in the placebo control group will receive free access to leisure activities, including visits to museums and theme parks as an incentive for his/her participation.
Study: NCT06378073

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Incentive Spirometer
Description: Specificity and sensitivity: Incentive spirometry is a specific type of spirometry that aims to encourage people to breathe deeply intentionally but does not provide a measurement or inform management of chronic lung diseases. Less than 5 repetitions per day (sensitivity 93%, specificity 77%) and less than 2 balls per repetition (sensitivity 93%, specificity 77%) were predictive of postoperative pulmonary complications. (1) Validity and reliability: Incentive spirometry can be used as a simple mean to follow lung function, especially VC, in the postoperative period in spontaneously breathing patients. Incentive spirometry is noninvasive and can be performed repeatedly at the bedside in the intensive care setting. (2)~Interpretation:~There are only three numeric values that are required to interpret spirometry:~* Forced Vital Capacity (FVC)~* Forced Expiratory Volume (FEV1)~* FEV1/FVC ratio.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Numeric Pain Rating Scale
Description: Sensitivity: The area under the receiver operator characteristic curve for the NRS as a test for pain that interferes with functioning was 0.76, indicating fair accuracy. A pain screening NRS score of 1 was 69% sensitive for pain that interferes with functioning. (4) he diagnostic value of different NRS cut-off values for administering analgesics is determined by an ROC curve. Sensitivity of NRS \> 3 for 'unbearable' pain in older patients was 72% with a specificity of 97·2%. With a cut-off point NRS \> 4, sensitivity increased to 83%, while specificity was 96·7%. (5) Validity and reliability: The numerical rating scale is a reliable and valid tool for pain assessment in patients with musculoskeletal impairments. (3)~Measurement (circle): Categorical /Numerical /Both:~Numerical:~The 11-point numeric scale ranges from '0' representing one pain extreme (e.g. no pain) to '10' representing the other pain extreme (e.g. pain as bad as you can imagine or worst pain imaginable)
Study: NCT06513182

Intervention type: OTHER
Group type: OTHER
Intervention: No Alexis orthopaedic protector
Description: No Alexis orthopaedic protector will be used during the course of the surgery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alexis orthopaedic protector
Description: Alexis orthopaedic protector will be inserted after making an initial superficial approach to the shoulder.
Study: NCT06549686

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CLS2901C (human [allogeneic] chondrocyte sheets)
Description: CLS2901C (human \[allogeneic\] chondrocyte sheets)
Study: NCT05904379

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: Subjects receive AK112 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: Subjects receive AK112 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: Subjects receive AK112 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: Subjects receive AK112 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: Subjects receive AK112 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: Subjects receive AK112 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: Subjects receive AK104 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: Subjects receive AK104 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: Subjects receive AK104 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: Subjects receive AK104 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: Subjects receive AK104 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: Subjects receive AK104 intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Subjects receive carboplatin intravenously.
Study: NCT04457271

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal Management Training (GMT)
Description: GMT is a structured, short-term cognitive remediation program with an emphasis on mindfulness and practice in planning and completion of goal-oriented behaviours. The main objective of GMT is to help participants regain executive control in order to better define goals and monitor performance in achieving them. Sessions include instructional material, interactive tasks, discussion of patients' real-life deficits, and homework assignments. Mindfulness meditation is also incorporated for the purpose of developing the skill of bringing one's mind to the present to monitor ongoing behaviour, goal states, and the relationship between them, and for the development of attentional control. The program incorporates real-life examples to illustrate goal attainment failures and successes, as well as in-session practice of complex tasks that mimic real-life tasks - typically a challenge for individuals with executive function deficits (e.g., planning and set-shifting tasks).
Study: NCT05904379

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Subjects receive carboplatin intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Subjects receive carboplatin intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Subjects receive carboplatin intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: paclitaxel
Description: Subjects receive paclitaxel intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: paclitaxel
Description: Subjects receive paclitaxel intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pemetrexed
Description: Subjects receive pemetrexed intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pemetrexed
Description: Subjects receive pemetrexed intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Subjects receive docetaxel intravenously.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Docetaxel
Description: Subjects receive docetaxel intravenously.
Study: NCT06097988

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ABIO3419
Description: Intra-articular injection
Study: NCT04795453

Intervention type: OTHER
Intervention: score system to predict the need for surgery
Description: two and more grades of NEC is assessed using the score system to predict the need for surgery

Intervention type: OTHER
Intervention: score system to predict the need for surgery
Description: two and more grades of NEC is assessed using the score system to predict the need for surgery

Intervention type: OTHER
Intervention: usual method to predict the need for surgery
Description: two and more grades of NEC is assessed using the usual method to predict the need for surgery

Intervention type: OTHER
Intervention: usual method to predict the need for surgery
Description: two and more grades of NEC is assessed using the usual method to predict the need for surgery
Study: NCT05758441

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mentoring to be Active plus Family
Description: Ten, structured peer mentoring sessions (once a week) covering new content each week and guided skill-building and practice. The MPBA sessions target increasing daily physical activity and replacing sugary drinks with water for hydration. Mentoring sessions are conducted virtually. A 6-month family reinforcement program follows with a reinforcement packet sent to child participants' homes once a month.
Study: NCT06500689

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Allisartan Isoproxil/Sustained-Release Indapamide
Description: Double-blind period (Week 1\~Week 12): Allisartan Isoproxil/Sustained-Release Indapamide.~Open-label period (Week 13\~Week 52): Allisartan Isoproxil/Sustained-Release Indapamide.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Allisartan Isoproxil
Description: Double-blind period (Week 1\~Week 12): Allisartan Isoproxil.~Open-label period (Week 13\~Week 52): Allisartan Isoproxil/Sustained-Release Indapamide.
Study: NCT05758441

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tracking Health and Fitness
Description: 10 self-guided, self-paced modules mailed to child participants home.
Study: NCT06412055

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NEURO SWING AFO (Fior& Gentz, Lüneburg In Duderstadt, Germany)
Description: stiffness-optimized custom-made spring-hinged AFO with the NEURO SWING® system ankle joint build in

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WalkOn Reaction® (Ottobock, Duderstadt)
Description: comparator: prefab spring-like AFO without hinge with a predefined stiffness (2.8 Nm/degree).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Matrix Max2® (TruLife, Dublin, Ireland)
Description: comparator: prefab spring-like AFO without hinge with a predefined stiffness (1.4 Nm/degree)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Matrix® (TruLife, Dublin, Ireland)
Description: comparator: prefab spring-like AFO without hinge with a predefined stiffness (0.6 Nm/degree)
Study: NCT05980403

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT04534803

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BCG Vaccine
Description: .1 mL of reconstituted BCG vaccine given intradermally at baseline.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: .1 nL of diluent (saline) given intradermally at baseline
Study: NCT06522503

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: stress ball
Description: The intervention group was provided with a stress ball to be held in both hands for a period of five minutes prior to the insertion of the port catheter needle. They were instructed to squeeze the ball in their hands at regular intervals until the conclusion of the procedure.
Study: NCT06283589

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INZ-701
Description: Recombinant fusion protein that contains the extracellular domains of human ENPP1 coupled with an Fc fragment from an immunoglobulin gamma-1 (IgG1) antibody.
Study: NCT06007794

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: JUMP group
Description: patients will have a femoral ultrasound and blood tubes in addition to the blood sample taken as part of the treatment
Study: NCT05470582

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Flu-M, Inactivated split influenza vaccine 0.5 mL
Description: Solution for intramuscular injection Сhildren were vaccinated with the Flu-M vaccine once/twice (all children were vaccinated twice with an interval of 28 days between the first vaccination and revaccination; if the child is vaccinated for the first time) intramuscularly in a dose of 0.5 mL

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaxigrip, Inactivated split influenza vaccine 0.5 mL
Description: Suspension for intramuscular and subcutaneous injection Children were vaccinated with the Vaxigrip® vaccine once/twice (all children were vaccinated twice with an interval of 28 days between the first vaccination and revaccination; if the child is vaccinated for the first time) intramuscularly in a dose of 0.5 mL

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Flu-M, Inactivated split influenza vaccine 0.25 mL
Description: Solution for intramuscular injection Children were vaccinated with the Flu-M vaccine twice (all children were vaccinated twice with an interval of 28 days between the first vaccination and revaccination) intramuscularly in a dose of 0.25 mL

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaxigrip, Inactivated split influenza vaccine 0.25 mL
Description: Suspension for intramuscular and subcutaneous injection Children were vaccinated with the Vaxigrip® vaccine twice (all children were vaccinated twice with an interval of 28 days between the first vaccination and revaccination) intramuscularly in a dose of 0.25 mL
Study: NCT04539301

Intervention type: DIAGNOSTIC_TEST
Intervention: Estimated anticoagulant level (conversion factor x anti-Xa activity)
Description: Estimated anticoagulant level (conversion factor x anti-Xa activity)

Intervention type: DIAGNOSTIC_TEST
Intervention: Estimated anticoagulant level (conversion factor x anti-Xa activity)
Description: Estimated anticoagulant level (conversion factor x anti-Xa activity)
Study: NCT06078176

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrical Rectal Stimulation
Description: Electrical stimulation of the rectum will be applied to activate sensory afferent neurons of the rectum and evoke a recto-colonic reflex to improve colonic motility and facilitate bowel emptying. This intervention will compared to individuals' usual mechanical intervention of digital rectal stimulation.
Study: NCT05659316

Intervention type: OTHER
Intervention: MRI imaging
Description: Knee MRI imaging
Study: NCT06678711

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: minimal invasive surgery-posterior atlantoaxial lateral mass joint fusion
Description: Make a 4.5 cm incision along the median line and then dissect the trapezius, splenius capitis, and semispinalis capitis muscle laterally 1.5 cm off the median line. Retract the obliquus capitis inferior muscle to expose the C1-C2 intra-articular space. Remove the articular cartilage, insert allogenic granular bone and 3D-printed cage. Place the screws and rod in the same positions as conventional surgery, and the operation is completed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open atlantoaxial fixation and fusion
Description: The Goel-Harms procedure will be used in the control group. Screws and rods are placed in the same position as in the experimental group, and a negative-pressure drain was placed until daily drainage was \<50 mL.