TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05285657

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)
Description: The interpretation of the two-step malaria RDT will be done as follow:~* PfHRP2(+)/pLDH(+): falciparum malaria or co-infection with non-falciparum malaria;~* PfHRP2(-)/pLDH(+): non-falciparum malaria or falciparum malaria with deletion of hrp2;~* PfHRP2(-)/pLDH(-): negative results~* PfHRP2(+)/pLDH(-): inconclusive results and information on previous antimalarial treatment is needed to differentiate:~Within the past 28 days:~* If previous antimalarial treatment is reported, the malaria diagnosis is reported as negative result. Nonetheless, the antimalarial treatment decision will be based on malaria microscopy;~* If previous antimalarial treatment is not reported, the malaria diagnosis is reported as positive result.~Other PoC tests for bacterial infections The two-step malaria RDT will be supported by PoC test listed above to diagnose bacterial or viral infection in all patients.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)
Description: The interpretation of the two-step malaria RDT will be done as follow:~* PfHRP2(+)/pLDH(+): falciparum malaria or co-infection with non-falciparum malaria;~* PfHRP2(-)/pLDH(+): non-falciparum malaria or falciparum malaria with deletion of hrp2;~* PfHRP2(-)/pLDH(-): negative results~* PfHRP2(+)/pLDH(-): inconclusive results and information on previous antimalarial treatment is needed to differentiate:~Within the past 28 days:~* If previous antimalarial treatment is reported, the malaria diagnosis is reported as negative result. Nonetheless, the antimalarial treatment decision will be based on malaria microscopy;~* If previous antimalarial treatment is not reported, the malaria diagnosis is reported as positive result.~Other PoC tests for bacterial infections The two-step malaria RDT will be supported by PoC test listed above to diagnose bacterial or viral infection in all patients.
Study: NCT05598931

Intervention type: DEVICE
Intervention: Transcranial Magnetic Stimulation
Description: Subjects will participate in an on-line neuro-navigation session in which 6 TMS coil positions will be recorded.
Study: NCT05326750

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gamma tACS (40 Hz) over the superior parietal cortex
Description: Single session of gamma tACS (40 Hz) over the superior parietal cortex

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Gamma tACS (40 Hz) over the superior parietal cortex
Description: Single session of gamma tACS (40 Hz) over the superior parietal cortex
Study: NCT06096350

Intervention type: DEVICE
Intervention: indirect calorimetry analysis
Description: indirect calorimetry analysis with K5 (COSMED, Italy) during six minute walk test or timed up and go test.
Study: NCT06074458

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Glucosano
Description: Glucosano is a remote patient monitoring diabetes dashboard with a patient facing Smartphone application

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Community Health Worker diabetes technology coach
Description: Community Health Workers will work with participants as a diabetes technology coach during scheduled and as needed visits
Study: NCT04866329

Intervention type: OTHER
Intervention: Blood sample
Description: Additional blood sampling at the end of ovarian stimulation monitoring (the eve of the oocyte pick-up)

Intervention type: OTHER
Intervention: Urine sample
Description: Collection of the first urine in the morning on the day of the oocyte pick-up

Intervention type: OTHER
Intervention: Follicular fluid and granulosa cells sample
Description: Collection of follicular fluid and granulosa cells during oocyte pick-up.
Study: NCT05388396

Intervention type: OTHER
Intervention: PIMS-TS diagnostic a treatment
Description: PIMS-TS diagnostic a treatment
Study: NCT06365541

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: oral Dapagliflozin tablets 10mg/day for 6 months
Study: NCT06608355

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Human Dopaminergic Progenitor Cells
Description: Single injection of Human Dopaminergic Progenitor Cells into the putamen of brain.
Study: NCT04771247

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cardia Band Ligation
Description: Patients will undergo cardia band ligation at the level of the GEJ.
Study: NCT06588673

Intervention type: OTHER
Group type: OTHER
Intervention: Art Thrapy
Description: Art therapy at Art Therapy Studio, a well-established recommended art therapy leader since 1967 with extensive experience in virtual therapy for patients with medical needs. Cheryl Pete, MA ATR-BC, a board-certified art therapist and the Clinical Director will complete the art therapy sessions. The art therapy will be a 1-hour sessions, once a week for a total of 8 weeks (or 8 sessions). Cheryl Pete's role will solely involve providing a service. Chery will complete the Art Therapy according to her standard practices. Cheryl's Art Therapy will not be altered in any way as a part of this research study. Cheryl will not collect any research data. As research participants are referred to Cheryl for the Art Therapy, the research participant's name and contact information will be shared.
Study: NCT06676618

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal Exercise Training
Description: The exercise training consisting of aerobic, strengthening and balance exercises will be applied for 12 weeks/3days for 1hour. One day of the exercise training will be performed in a clinical environment with a physiotherapist, and the other 2 days of the week, participants will be asked to apply asynchronous video-based telerehabilitation over the internet in their own homes. The asynchronous video-based telerehabilitation application will be performed through an account created specifically for the participant on the www.telenororehab.com website. The exercise program will be created according to the individual's condition and progression will be provided every 3 weeks. Patients who do not attend 3 consecutive sessions will be excluded from the study.

Intervention type: OTHER
Group type: OTHER
Intervention: Control Group
Description: Participants in the control group will be placed on the waiting list after all evaluation methods have been applied and will be re-evaluated at the end of 12 weeks. After the evaluations, individuals in the control group will also be given multimodal exercise training.
Study: NCT06616519

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BenQ Materials MSENCI soft hydrophilic contact lenses
Description: Test lenses were to be worn for approximately 90 days.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Visco Oxypure Color soft hydrophilic contact lenses
Description: Control lenses were to be worn for approximately 90 days
Study: NCT06678425

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Peripheral magnetic stimulator
Description: a non-invasive method of delivering a rapidly pulsed, high-intensity magnetic field to peripheral muscles

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Peripheral magnetic stimulator
Description: The same coil as real rPMS, but in a position perpendicular to the skin
Study: NCT06678399

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KELI-101
Description: KELI-101 consists of ex vivo expanded placental mesenchymal stromal cells (PMSCs) in a 10% cryopreservation solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KELI-101
Description: KELI-101 consists of ex vivo expanded placental mesenchymal stromal cells (PMSCs) in a 10% cryopreservation solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KELI-101
Description: KELI-101 consists of ex vivo expanded placental mesenchymal stromal cells (PMSCs) in a 10% cryopreservation solution.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle (placebo)
Description: Plasmalyte
Study: NCT06679205

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multidisciplinary and multimodal intervention
Description: The PAINDOC Program consists in:~* Therapeutic education: The therapeutic education block consists of 2 parts: a 2-hour education session called Empowered Relief® and 2 1-hour pain neuroscience education sessions.~* Psychotherapy: The psychotherapy part consists of 1 group session of 1 hour, face-to-face and with groups of up to 15 people.~* Therapeutic exercise: The therapeutic exercise module consists of 3 sessions of 1 hour each, face-to-face, with small groups of between 6 and 10 patients, and given by the physiotherapist of the pain unit.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: The pharmacological treatment will be individualised according to pain intensity, contraindications and the appearance of adverse effects.
Study: NCT06678308

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Embolisation with Magic Glue®
Description: Magic Glue® will be injected within prostatic arteries, leading to ischaemia and necrosis of part of the adenomatous tissue of the prostate gland

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Embolisation with Embosphere®
Description: Embosphere® will be injected within prostatic arteries, leading to ischaemia and necrosis of part of the adenomatous tissue of the prostate gland
Study: NCT06392802

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rehabilitation treatment using Muvity
Description: The users have the support of the telerehabilitation system Muvity
Study: NCT06413927

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online Vehicle and Driver Safety Training
Description: This online video education program provides education in vehicle and driver safety (e.g. vehicle maintenance, adjusting car seats and seatbelts). This online training will take up to 2 hours to complete and will have a short quiz at the end to determine compliance with this online training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online Driver Skills Training
Description: The online driver training is the Accelerated Curriculum to Create Effective Learning (ACCEL) is designed to enhance the ability to anticipate, recognize and respond to hazards and to maintain attention to the road. The training is delivered online via a computer and can be done from home or at a school or other site that has a computer with internet access. It requires up to two hours to complete, and will be hosted on a platform that will track progress and completion through the training (such as accuracy, duration in modules, time to complete) and a short quiz will be provided at the end to assess learning.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behind-the-Wheel Driver Training
Description: The professional behind-the-wheel training course will be conducted in-person, delivered by local driving school partner Driver Training Services. The curriculum consists of 6 hours of training with assigned practice between lessons, and meets Pennsylvania and national standards. Post-lesson forms completed by the instructors will record adherence and consistency (intervention fidelity).
Study: NCT05753618

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Granulocyte Colony-Stimulating Factor (G-CSF)
Description: Participants will receive G-CSF injection (either filgrastim or pegfilgrastim) after each paclitaxel cycle of DD-AC/T chemotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omission of Granulocyte Colony-Stimulating Factor (G-CSF)
Description: Participants will omit the use of G-CSF (either filgrastim or pegfilgrastim) after each paclitaxel cycle of DD-AC/T chemotherapy
Study: NCT04705025

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavior Therapy
Description: Undergo CBSM using the BNT001 app
Study: NCT05833334

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Public health infographic (AIM 3)
Description: Standard public health infographic about home air radon testing, plus information about requesting a free home air radon test kit

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online health promotion intervention tailored by smoking status (AIM 3)
Description: Online health promotion intervention with messaging about home air radon testing tailored by the participant's stated smoking status, plus information about requesting a free home air radon test kit

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online health promotion intervention tailored by smoking status, plus reminder messages (AIM 3)
Description: Online health promotion intervention with messaging about home air radon testing tailored by the participant's stated smoking status, plus information about requesting a free home air radon test kit, plus reminder messages about home air radon testing sent over two months

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Focus group with educational overview (AIM 1)
Description: 90-minute online focus group discussion about home air radon testing, plus an educational overview about home air radon testing using a standard public health infographic
Study: NCT05678582

Intervention type: DIAGNOSTIC_TEST
Intervention: Liver biopsy
Description: liver biopsy were taken then evaluated by histopathological examination

Intervention type: DIAGNOSTIC_TEST
Intervention: Liver biopsy
Description: liver biopsy were taken then evaluated by histopathological examination
Study: NCT04834674

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: DEB-TACE combined with apatinib and PD-1 antibody
Description: combination of local therapy (DEB-TACE), antiangiogenic therapy (apatinib), and immunotherapy (PD-1 antibody)
Study: NCT04107649

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Basic Study Activities
Description: Basic study activities begin two-weeks before TKR and end approximately 24-months after TKR. Basic study activities include: two in-person visits at the local clinic site (2 weeks before TKR and 32-weeks after TKR), having check-in calls with study staff weekly from weeks 1-13 after surgery and every other week for weeks 14-31, completing 6 surveys, and wearing an ActiGraph activity tracker (waist-worn) for five one-week periods throughout the study (2-weeks before-TKR, 32-weeks post-TKR, one-year post-TKR, 18-months post-TKR, two-years post-TKR). All participants will be eligible to receive up to $235 for completing these activities over the course of two years.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Basic Study Activities
Description: Basic study activities begin two-weeks before TKR and end approximately 24-months after TKR. Basic study activities include: two in-person visits at the local clinic site (2 weeks before TKR and 32-weeks after TKR), having check-in calls with study staff weekly from weeks 1-13 after surgery and every other week for weeks 14-31, completing 6 surveys, and wearing an ActiGraph activity tracker (waist-worn) for five one-week periods throughout the study (2-weeks before-TKR, 32-weeks post-TKR, one-year post-TKR, 18-months post-TKR, two-years post-TKR). All participants will be eligible to receive up to $235 for completing these activities over the course of two years.
Study: NCT04939207

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CT-FFR
Description: CT-images will be processed by an algorithm to calculate FFR-values of the full coronary tree

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Angiography-derived FFR
Description: FFR-values are calculated during coronary angiography based on the acquired images of the coronary arteries

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Angiography with invasive FFR-measurements
Description: during coronary angiography, a specialized pressure wire is passed through the coronary stenosis to calculate FFR based on the difference between the actual pressure and the expected pressure in the hypothetical healthy coronary artery.
Study: NCT05452941

Intervention type: DIAGNOSTIC_TEST
Intervention: Diagnostic test on urine samples
Description: Testing by BinaxNOW® S. pneumoniae and serotype-specific urine antigen detection (UAD) assays (UAD-1 and UAD-2).

Intervention type: DIAGNOSTIC_TEST
Intervention: Diagnostic test on urine samples
Description: Testing by BinaxNOW® S. pneumoniae and serotype-specific urine antigen detection (UAD) assays (UAD-1 and UAD-2).
Study: NCT05820074

Intervention type: DIAGNOSTIC_TEST
Intervention: Neural Activity Recording
Description: Neural Activity is measured using EEG in all groups. Additionally, in Parkinson's patients, local-field-potentials from deep brain stimulation electrodes are recorded.

Intervention type: DIAGNOSTIC_TEST
Intervention: Neural Activity Recording
Description: Neural Activity is measured using EEG in all groups. Additionally, in Parkinson's patients, local-field-potentials from deep brain stimulation electrodes are recorded.

Intervention type: DIAGNOSTIC_TEST
Intervention: Neural Activity Recording
Description: Neural Activity is measured using EEG in all groups. Additionally, in Parkinson's patients, local-field-potentials from deep brain stimulation electrodes are recorded.

Intervention type: DIAGNOSTIC_TEST
Intervention: Movement Parameter Recording
Description: Gait-related movement parameters are non-invasively recorded using motion capture, accelerometers and electromyography.

Intervention type: DIAGNOSTIC_TEST
Intervention: Movement Parameter Recording
Description: Gait-related movement parameters are non-invasively recorded using motion capture, accelerometers and electromyography.

Intervention type: DIAGNOSTIC_TEST
Intervention: Movement Parameter Recording
Description: Gait-related movement parameters are non-invasively recorded using motion capture, accelerometers and electromyography.

Intervention type: OTHER
Intervention: Neuromodulation
Description: Neural signals are recorded with the electrodes of the deep brain stimulation device. Parkinson's patients are asked to modulate their neural activity by observing the streamed neural activity and applying mental strategies.
Study: NCT05947513

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Curcumin
Description: Curcumin formulation with enhanced bioavailability which contains food-grade curcumin 35% (w/w) combined with the galactomannan fiber from fenugreek seeds.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Palliative radiotherapy
Description: As per the treatment guidelines of the Tikur Anbessa Hospital Radiotherapy Center, standard-of-care palliative or non-radical radiotherapy entails treatment of advanced cervical cancer patients at a biologically effective dose of 45-55 Gy over the course of three to five weeks.
Study: NCT05835466

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: reparixin
Description: reparixin at 1200mg TID three times per day.
Study: NCT06068738

Intervention type: OTHER
Intervention: Biological sample collection
Description: Collection of ascites, blood and fresh tumour tissues (if available)

Intervention type: OTHER
Intervention: Biological sample collection
Description: Collection of ascites, blood and fresh tumour tissues (if available)
Study: NCT05783817

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3,4-Methyl enedioxy methamphetamine
Description: MDMA (3,4 methylenedioxymethamphetamine) is a synthetic, psychoactive drug that is chemically similar to the stimulant methamphetamine.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methamphetamine
Description: Methamphetamine is a stimulant that affects the central nervous system. This is used as a control in the study.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy (CBT)
Description: Cognitive Behavioral Therapy with exposure and response prevention performed by therapist team.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy (CBT)
Description: Cognitive Behavioral Therapy with exposure and response prevention performed by therapist team.
Study: NCT06555081

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib IR
Description: Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib IR
Description: Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib XR
Description: Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib XR
Description: Tablet
Study: NCT06566300

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: injection of autologous nanofat grafting
Description: Injection of nanfat graft

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: microneedling with autologus nanofat graft
Description: delivery of nanofat graft with microneedling
Study: NCT06568393

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calisthenic exercise
Description: Calisthenic exercise program was included: jumping jack, burpee, mountain climber, squat thrust, squat, squat jump, split and alternate exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Calisthenic exercise
Description: Calisthenic exercise program was included: jumping jack, burpee, mountain climber, squat thrust, squat, squat jump, split and alternate exercises.
Study: NCT05589597

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EO4010
Description: Sequential assignment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EO4010
Description: Sequential assignment
Study: NCT06151431

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Alpha-Agonist
Description: The maternal systolic blood pressure was consistently maintained above 80% of the preoperative baseline value from the initiation of spinal anesthesia until fetal delivery.
Study: NCT05589597

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EO4010
Description: Sequential assignment
Study: NCT06113367

Intervention type: OTHER
Intervention: Evaluation of anti-PD-(L)1 immunotherapy efficacy
Description: Non Applicable, research on data
Study: NCT06529237

Intervention type: DIAGNOSTIC_TEST
Intervention: LDH-based malaria rapid diagnostic test
Description: Malaria testing using an LDH-based malaria rapid diagnostic test will be added to standard routine testing of suspected cases at health facilities
Study: NCT05691803

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise intervention
Description: The 6 month intervention consists of usual care (PaP) plus an initial 12 weeks of instructor led exercise (described below) followed by a 12 week period in where the participant will have to conduct their physical activity on their own.~Exercise intervention:~Participants are invited to a 12 week exercise intervention at a private fitness center after they have received their PaP. The exercise, including a variety of aerobic and resistance training, is performed in a group setting starting with one session per week for the first three weeks and then two sessions per week for week 4-12. A follow-up session is also included after 12 weeks in where a physiotherapist contact the participant and discuss how they will adhere to their Physical activity on prescription.