TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05157438

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: virtual reality device
Description: The virtual reality device is a 3D head-mounted display which provides a wide field of view and a high-resolution visual display, it has been used to manage cases of phobia and extreme fear through the use of exposure-based treatment programs. The virtual reality system consists of head mounted glasses, a compatible smartphone and headphones. This technology creates a computer stimulated virtual environment into which the child can be entirely immersed. It works to distract the brain from the painful procedure and reduce the perception of pain stimuli

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: screen programs
Description: the screens are used for distraction during dental treatments. they could be on tablets, iPads or televisions.
Study: NCT04792008

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: YQ23
Description: Single dose of 120 mg/kg YQ23 via intravenous route will be evaluated

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Matching placebo
Description: Single dose of 0.9% normal saline via intravenous route as matching placebo
Study: NCT05777746

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 12-week plant-based dietary program
Description: a 12-week plant-based dietary program consisting of information via an online platform, online guidance by dieticians and in online peer support groups. Patients will aim to maximize their intake of plant-based products while reducing their of animal products as much as possible.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Usual Diet
Description: Patients in the control group continue with their usual diet and/or usual dietary care. Patients in the control group will be offered access to the online platform at 24 weeks.
Study: NCT06154187

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PBK_L2201
Description: Abaloparatide-SC 80 μg was to be self-administered daily using a Pen Injector device.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo was formulated similar to abaloparatide-SC.
Study: NCT06101030

Intervention type: DEVICE
Intervention: Signal On
Description: InSee monitor patient signals are on.
Study: NCT05629364

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KIO-101
Description: Randomized, Controlled

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KIO-101
Description: Randomized, Controlled

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: KIO-101
Description: Randomized, Controlled
Study: NCT04958811

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tiragolumab
Description: 600mg IV administered every 3 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: 1200mg IV administered every 3 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: 15mg/kg IV administered every 3 weeks.
Study: NCT06250530

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High tibial osteotomy using TOMOFIX
Description: TOMOFIX: A guidepin is placed to determine the level and length of the osteotomy with an appropriate hinge position selected. The oscillating saw is then used along with osteotomes to complete the osteotomy under image intensifier guidance. This is opened to the desired width of correction with a trapezoidal gap noted when using laminar spreader in the posterior position to avoid slope change. The plate is then applied and secured as per manufacturers operative technique.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: High tibial osteotomy using BodyCAD
Description: BodyCAD: The patient specific cutting block is applied to the proximal tibia and secured in placed. The osteotomy is then created with sequential drills and osteotome and opened to the predetermined correction as per the manufacturer's guidelines. The plate is applied and secured with the supplied screws.
Study: NCT05866718

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Compassionate Touch Intervention
Description: Participants will be taught the micropractice (\<20-second/day personal practice) via video recording.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Habit Formation Tools
Description: Participants will receive evidence-based tools for promoting habit-formation.
Study: NCT04769115

Intervention type: DEVICE
Group type: OTHER
Intervention: Alert for temperature delta
Description: If alert for potential complications refer to appropriate specialist
Study: NCT05750706

Intervention type: OTHER
Intervention: observation of invasive fungal infections
Description: observation of invasive fungal infections during chemotherapy
Study: NCT05758909

Intervention type: DEVICE
Intervention: TF TAVI
Description: Follow-up Observation of patients having received a TF-TAVI
Study: NCT05924867

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: plasma activated saline
Description: The plasma activated normal saline used in the intervention was prepared by a self-made machine, and the safety of the plasma activated water produced by the machine has passed the national quality inspection.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine nursing
Description: For postoperative incision infection group and infected ulcer group, conventional dressing change treatment was given, namely chlorhexidine disinfectant washing, drainage and bandaging; For the fat liquefaction group, conventional treatment was given, namely negative pressure suction.
Study: NCT05279690

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine
Description: Patients will receive 14 days of colchicine in the absence of prohibitive toxicity of disease progression

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine
Description: Patients will receive 14 days of colchicine in the absence of prohibitive toxicity of disease progression

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine
Description: Patients will receive 14 days of colchicine in the absence of prohibitive toxicity of disease progression
Study: NCT05027802

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palovarotene
Description: Palovarotene will be taken orally once daily at approximately the same time each day.
Study: NCT06565117

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: White yu green skin lotion
Description: Group A: Systemic emollient was applied twice daily for 8 weeks Group B: Continue applying skin lotion twice daily in locally affected skin areas or in areas previously affected by AD for 8 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: White yu green skin lotion
Description: Group A: Systemic emollient was applied twice daily for 8 weeks Group B: Continue applying skin lotion twice daily in locally affected skin areas or in areas previously affected by AD for 8 weeks
Study: NCT05928988

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554；Itraconazole
Description: Drug: SHR8554 Administered as specified in the treatment arm Drug: Itraconazole Administered as specified in the treatment arm
Study: NCT06634524

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmeditomidine
Description: Patients who will receive IV infusion of (0.2 µg/kg/hr dexmeditomidine).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Patients who will receive IV infusion of normal saline, at the same rate of dexmedetomidine infusion.
Study: NCT04870788

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Relaxation
Description: Participate in mindfulness program

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Relaxation
Description: Participate in mindfulness program

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group II (mindfulness waitlist)
Description: Patients and their partners participate in mindfulness program together or separately, depending on their preference, as in Group I beginning 12 weeks after starting the study and completing the third study visit.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group II (mindfulness waitlist)
Description: Patients and their partners participate in mindfulness program together or separately, depending on their preference, as in Group I beginning 12 weeks after starting the study and completing the third study visit.
Study: NCT06293339

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: CHMI with 3D7 malaria
Description: Controlled human malaria infection with 3D7 malaria through mosquito bites

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CHMI with 3D7 malaria
Description: Controlled human malaria infection with 3D7 malaria through mosquito bites
Study: NCT03096262

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Output-Focus Condition
Description: Users are asked to tag more, and force feedback is exerted the more points the user has

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Output-Focus Condition
Description: Users are asked to tag more, and force feedback is exerted the more points the user has

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Input-Focus Condition
Description: Users are asked to tag more and force feedback is exerted based on the number of images the user has analyzed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Input-Focus Condition
Description: Users are asked to tag more and force feedback is exerted based on the number of images the user has analyzed.
Study: NCT04900298

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SafeHaven Automated Hand Hygiene Device
Description: Anesthesia providers in the intervention arm will be given a personal hand hygiene device, containing 64% ethyl alcohol, which provides actionable real-time performance feedback. The personalized device will be affixed to the provider's waist and will remain there for use throughout the perioperative period. Performance feedback is given to the anesthesia provider in real time with the number of personal hand hygiene events and an hourly hand hygiene rate, which is displayed on the device. Devices will be handed out to participating providers in the preoperative bay and retrieved in the post-anesthesia care unit upon case completion.
Study: NCT05523258

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Computerized cognition training
Description: The researchers distribute tablet computers for the patients. The patients in this group receive cognitive function training under the guidance of a full-time cognitive function trainer. The training time is about 45-60 minutes every time, and the frequency is twice a day until the operation. After the operation, cognitive function training should be started as soon as possible when the patient meets the following conditions including Glasgow score ≥ 12, no mechanical ventilation and no sedative drugs. The training intensity is the same as that before operation, generally starting from the 2nd to 3rd day after operation and continuing to discharge or the 7th day after operation.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Basic training based on tablet computer
Description: The researchers distribute the same tablet computer to the patients. The patients in this group receive basic training under the guidance of a full-time cognitive function trainer. The training duration is the same as that of the test group.
Study: NCT04806113

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Moderna COVID-19 vaccine
Description: Two doses from the Moderna vaccine will be administered intramuscularly. The time between dose 1 and dose 2 of the vaccine will be 28 days.
Study: NCT05427890

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: T2D Risk Communication Tool: Relative Risk
Description: Risk of T2D is presented in comparison to the rest of the Singapore population in a scale 1-10. Suggestions on different lifestyle changes and its potential to reduce the individual's relative risk is presented for user to observe impact of preventative behaviours.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: T2D Risk Communication Tool: Metabolic Age
Description: Risk of T2D is presented as an age, compared to their chronological age as a proxy for their current health status. Suggestions on different lifestyle changes and its potential to reduce the individual's metabolic age is presented for user to observe impact of preventative behaviours.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: T2D Risk Communication Tool: Traffic Light
Description: Risk of T2D is presented as either High (Red) or Low (Green). Generic tips on how to reduce risk of diabetes are included. This imitates the tool that is currently available for residents of Singapore to use to assess their risk of T2D.
Study: NCT06051500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nostril focus followed by belly focus
Description: Focused breathing on the nostrils followed by focus breathing on the belly.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Belly focus followed by nostril focus
Description: Focused breathing on the bellyfollowed by focus breathing on the nostrils.
Study: NCT04656561

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANX007
Description: Form: solution for injection; Route of Administration: IVT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANX007
Description: Form: solution for injection; Route of Administration: IVT
Study: NCT06555705

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The control group will be given placebo for 3 months

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Omega 3
Description: The interventional group will be given omega 3 for 3 months
Study: NCT05056467

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Induction of Labor
Description: Induction of Labor at 39 weeks of gestation
Study: NCT06171295

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Blood draw
Description: The blood draws in specified time points
Study: NCT05257785

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lymfit exercise intervention
Description: Participants randomized to this arm will be allocated a pre-registered Inspire II / Charge IV model Fitbit. The kinesiologist of the study will meet with the participants for a baseline fitness assessment. The kinesiologist will examine the baseline physical activity levels, fitness level and sedentary behaviours of the participants, to design a personalized exercise prescription. Within one week after the baseline fitness assessment, the kinesiologist will contact the participants to discuss the exercise prescription. Every two weeks there-after, the kinesiologist will follow up with the participants via videoconferencing to discuss their progress and to modify or advance their exercise prescriptions as needed. Participants will be followed-up at 6 months and 12 months.
Study: NCT04656561

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham comparator
Description: Form and Route of Administration: pressure to mimic IVT injection

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham comparator
Description: Form and Route of Administration: pressure to mimic IVT injection
Study: NCT05647616

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strengthening exercises
Description: Participants in group A will be required to complete 12 sessions in 4 to 6 weeks. Resistance-Bands will be used to do ankle plantar flexion and eversion (3 sets of 10 repetitions). Participants will have to be seated on the floor with the knee extended and instructed to perform the movement at the ankle joint without allowing extraneous movement at hip and knee. The resistance band will be doubled and securely attached to the base of a table. The training resistance will be determined by calculating 70% of the resting length of the resistance band and adding this distance to the resting length of the resistance band. Using this calculated distance, the examiner will place a mark to which the resistance band will be stretched during exercise performance on the floor. Each week a study investigator will track each participant's completion. Participants will be instructed to move through their entire range of motion for the direction of each exercise.
Study: NCT06136416

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire for Non-dystrophic myotonias
Description: Patients will have to complete the questionnaire created specifically for their pathology, as well as an evaluation grid of the same questionnaire to assess its relevance and good understanding
Study: NCT05306392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Moderate Hypothermia
Description: moderate hypothermia will be induced using the heat controller of the VV-ECMO circuit. Temperature will be maintained between 33°C≤ T°C ≤34°C during 48 hours followed by a progressive reheating (0.2±0.1°C/h) to reach 36 °C. Temperature at 36°C will be maintained during 48 hours after having reached 36 °C.
Study: NCT06417060

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caudal block anesthesia
Description: Anesthesia will be administered via inhalation induction with air/nitrous oxide and sevoflurane, followed by an injection of 0.25% bupivacaine (1 mL/kg) without epinephrine into the caudal canal, which is the sacral portion of the spinal canal.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Dorsal penile block anesthesia
Description: Anesthesia will be administered using an inhalation induction method with air/nitrous oxide and sevoflurane, followed by the injection of 0.25% bupivacaine without epinephrine into the dorsal part of the penis.
Study: NCT05306392

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Normothermia
Description: Temperature at 36°C will be maintained during 48 hours after having reached 36 °C
Study: NCT05257785

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Waitlist control
Description: Participants will be contacted by the study kinesiologist for a baseline fitness assessment 3 months after they consent, participants will be given a Fitbit, a personalized exercise prescription and receive bi-weekly follow-ups for 12 weeks.
Study: NCT05735886

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Softgel containing placebo
Description: Single oral dose administration (4 softgels) to be orally administered daily according to the randomization for 28 days

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Softgel containing 250mg of Urolithin A (Mitopure)
Description: Single oral dose administration (4 softgels) to be orally administered daily according to the randomization for 28 days
Study: NCT05647707

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: L-Carnitine
Description: The 36 patients will receive conventional supportive care in addition to IV L-carnitine with a loading dose of 100 mg/kg IV over 30-60 min (maximum 6 g) and the maintenance dose of 50 mg/kg IV every 8 h.
Study: NCT04436926

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: opioid approach bias modification
Description: The investigators will use a training version of the Approach-Avoidance Task (AAT), in which patients are asked to respond to the format of presented pictures, irrespective of the pictures' content. Pushing a presented picture away will decrease picture size, whereas pulling a picture closer will increase size. There are 2 categories of pictures; 20 different opioid and 20 different non-medication alternative pain managing activities. Training effect is achieved by presenting opioid pictures in push format only and non-opioid pictures in pull format only. Two hundred training trials are presented per session.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: sham training
Description: Sham training is identical to opioid approach bias training, except pictures are presented randomly in both formats.
Study: NCT05648786

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Laddr® plus Behavioral- Group and individual counseling
Description: Smartphone application utilizing the Community Reinforcement Approach (CRA) to facilitate social support in substance use treatment.~Outpatient treatment will include a range of services, including group counseling, individual counseling, medication treatment, and other recovery support services.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral- Group and individual counseling
Description: The active control condition consists of standard outpatient treatment for substance use disorders. Outpatient treatment will include a range of services, including group counseling, individual counseling, medication treatment, and other recovery support services.
Study: NCT06298214

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Her Health Program
Description: Addition of a community health worker navigator to assist subject in navigating their health in the first year postpartum.
Study: NCT05244915

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental (Delphi Surveys)
Description: The Delphi method, a process used to arrive at a group opinion or decision by surveying a panel of experts, will be used with experts in geriatric oncology to develop a supportive care management intervention for older caregivers of older adults with cancer.
Study: NCT04270175

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab SC
Description: Given as 1800mg via injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Given as 4mg oral capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Given as 20mg or 40 mg IV and 20mg or 40mg oral tablet.