TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05604183

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: non-invasive hyperspectral retinoscopy
Description: The Principal Investigator or a trained medical nurse (under the supervision of the principal investigator) will take an image of the retina of the patient with the Mantis Photonics hyperspectral retinoscopy camera.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: blood sample
Description: The Principle Investigator or a trained medical nurse (under the supervision of the Principal Investigator) will draw a small blood sample according to the standard medical procedures for drawing blood samples.
Study: NCT06179472

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BALT GOLDBAL2 Balloon
Description: Placement and retrieval of the GOLDBALLOON Detachable Balloon for severe CDH
Study: NCT05759884

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-VEGF
Description: Intravitreous injection of anti-VEGF drugs

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anti-VEGF
Description: Intravitreous injection of anti-VEGF drugs

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: subthreshold micropulse laser
Description: 577nm micropulse laser photocoagulation therapy
Study: NCT05397236

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine- Magnesium
Description: Patients received QL block with 20 ml of 0.25% bupivacaine (2, 4)plus 5 ml of 10% MgSO4.
Study: NCT05604183

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Test of cognitive ability on tablet computer with CoGNIT software
Description: The Principle Investigator or a trained medical nurse (under the supervision of the Principal Investigator) will give the patient to perform the digital cognitive test on a commercial tablet computer. The Principal Investigator or the medical nurse will be available for the patient to ask questions while the test is ongoing.
Study: NCT05397236

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine dexamethasone
Description: Patients received QL block with 20 ml of 0.25% bupivacaine (2,4)plus 2 ml of 8 mg dexamethasone plus 3 ml of 0.9% NS.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine saline
Description: Patients received QL block with 20 ml of 0.25% bupivacaine (2,4)plus 5 ml of 0.9% NS.
Study: NCT06559423

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: non-ablative Er:YAG laser and high intensity Tesla magnetic stimulation (HITS)
Description: Patients will initially undergo three monthly intravaginal treatments with the Er:YAG laser. Six weeks after the final laser treatment, patients will receive six sessions of magnetic stimulation. During these sessions, patients will sit on a specialized chair that generates a therapeutic magnetic field.
Study: NCT04941586

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education in pain, Manual Therapy and Exercises
Description: twice a week, lasting 60 minutes, for one month

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual Therapy and Exercises
Description: twice a week, lasting 40 minutes, for one month
Study: NCT06083584

Intervention type: OTHER
Intervention: RNA sequencing
Description: RNA-Seq (Sureselect XT HS2 RNA) from patient blood sample

Intervention type: OTHER
Intervention: RNA sequencing
Description: RNA-Seq (Sureselect XT HS2 RNA) from patient blood sample

Intervention type: OTHER
Intervention: RNA sequencing
Description: RNA-Seq (Sureselect XT HS2 RNA) from patient blood sample
Study: NCT05573802

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab Mafodotin-Blmf
Description: Blmf will be available as 100 mg/vial in single-use vial for reconstitution, supplied as lyophilized powder. Blmf will be delivered as IV solution over at least 30 minutes.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide will be administered per os.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone will be administered intravenously or per os.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirogacestat
Description: Nirogacestat will be administrated each day for all subsequent cycles were Blmf is also administrated.
Study: NCT05075369

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: water drinking test
Description: Water drinking test-glaucoma diagnostic test - marker for outflow facility reserve to detect IOP instability when the body ingests 800 ml of water within a 5 minute period of time
Study: NCT05093205

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-06882961
Description: Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-06882961
Description: Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Syrup

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levonorgestrel & Ethinyl Estradiol
Description: Tablet
Study: NCT06156644

Intervention type: DEVICE
Group type: OTHER
Intervention: PFA
Description: Ablation to treat trail fibrillation
Study: NCT05407623

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PAX Good Behavior Game
Description: PAX GBG is packaged into ten specific tools that the teachers are trained to introduce in in their classroom management practice. The program introduces verbal and visual cues that facilitate prosocial and attentive behaviors One of the core elements of the program is the PAX-game, meaning that the children - while focusing on ordinary school tasks like math - get to play a game in teams where each team tries to make as few classroom rules infractions as possible during a certain period of time. The teams that succeed in achieving predetermined goals get a reward (often a fun and desirable activity) that serves as a reinforcer of prosocial and task-oriented behaviors.~Supervision is performed individually with each teacher and included that the PAX-trainer observes a lecture given by the teacher before each supervision session.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Count on Me!
Description: Count on me! is set in adventure game where the child has an avatar that travels thru different worlds/platforms by using their mathematical skills. The child starts of in the home of the avatar, in a house like environment, where the child discovers a magical map that brings the child into a different world called Numberia. During the adventures in Numberia the child learns that it has certain skills, called the mathemagical powers, that will be used to liberate Numberia from the evil Prince Claw that has captured all the beautiful things (e.g., the birds that used to sing in the forest).~Count on me! was developed within a behavior analytic framework using a nonlinear programming process.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Collegial Learning Community
Description: Collegial learning community is a feasible way of professional learning for teachers according to the five cyclical steps. The teachers go through the first step that is to assess the skill or knowledge gaps for students, using various data sources (for example testing, grades, surveys, student interviews). The second step is to reflect upon what skills the teacher needs to acquire in order to help the students to meet the goals. The third step is to deepen the professional knowledge and skills. The fourth step is engaging the students in the new practice, and in the fifth step to evaluate the impact the new practice has had on student outcomes.~In Collegial learning community teachers take help from their peers in each of these steps in a structured way. For example, way of deepening tacit or procedural knowledge (in step two) is to visit a colleague during class and make observations on their classroom practice.
Study: NCT05296967

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: chewing
Description: patients are asked to chew chewing gum X 3/ day
Study: NCT05916872

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: experimental group
Description: Patients will receive Proprioceptive Neuromuscular Facilitation (contract-relax) technique with EMS

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control group
Description: Patients will receive conventional therapy.
Study: NCT04738955

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Micafungin Sodium
Description: micafungin sodium ≥ 100, \<200mg/time, once a day, intravenous drip. Low dose group
Study: NCT05264350

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sialic acid nasal spray
Description: The nasal spray will be self administered twice daily for 8 weeks.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Isotonic Saline Nasal Spray
Description: The nasal spray will be self administered twice daily for 8 weeks.
Study: NCT06030934

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: envafolimab and lenvatinib combined with paclitaxel-albumin
Description: envafolimab: 200mg d1,15 s.c. Q4W; lenvatinib: 8mg (\<60kg) or 12mg (≥60kg) p.o. Q.d.; paclitaxel-albumin: 100 mg/m2 d1,8,15 stop for one week, i.v. Q4W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: envafolimab and lenvatinib combined with paclitaxel-albumin
Description: envafolimab: 200mg d1,15 s.c. Q4W; lenvatinib: 8mg (\<60kg) or 12mg (≥60kg) p.o. Q.d.; paclitaxel-albumin: 100 mg/m2 d1,8,15 stop for one week, i.v. Q4W
Study: NCT04816240

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midodrine
Description: 5mg thrice daily and will be increased every 3 days upto 15 mg thrice daily with target MAP (\>75 mm and \<90)

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Albumin
Description: 80grams/week for 2 weeks followed by 40gram/week

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Albumin
Description: 80grams/week for 2 weeks followed by 40gram/week

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Medical Treatment
Description: Standard Medical Treatment
Study: NCT05396859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine and Cedazuridine
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Entrectinib
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laboratory Biomarker Analysis
Description: Correlative studies
Study: NCT04816240

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Medical Treatment
Description: Standard Medical Treatment

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT04715152

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ACB group
Description: Patients will receive ultrasound-guided (USG) ACB with bupivacaine and dexamethasone 30 minutes before spinal anesthesia and sham intra-articular normal saline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: IA group
Description: Patients will receive intra-articular bupivacaine and dexamethasone at the end of surgery and sham USG-ACB with normal saline
Study: NCT06426004

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: patients will receive NPH education
Description: Patients will benefit from the Hydrocephalus Association's (HA) educational strategy for idiopathic normal pressure hydrocephalus (iNPH) emphasizes patient collaboration in the development of educational materials specifically for this condition. HA has a library of assets that include PowerPoint presentations, videos, and online and print educational materials. There will be also in-person outreach resulting recruitment, website (the study website and HA website), webform (with a symptom of gait, dementia, and bladder symptoms), YouTube videos. The investigators will also go to the communities like senior centers, health fair, and churches, then we will give a talk about iNPH. These resources will be carefully adjusted to suit low-income demographics, guided by feedback from Baltimore audiences and HA's iNPH volunteers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: primary care physicians (PCPs) will receive professional NPH education
Description: A comprehensive professional development program for PCPs and CHWs, featuring presentations, educational videos, webinars, and tools on iNPH diagnosis, treatment, and care management. Provider Continuing Medical Education (CME) credits will be offered for in-person lectures, aiming to equip PCPs with the skills needed to address iNPH in low-income settings effectively

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: primary care physicians (PCPs) will receive professional NPH education
Description: A comprehensive professional development program for PCPs and CHWs, featuring presentations, educational videos, webinars, and tools on iNPH diagnosis, treatment, and care management. Provider Continuing Medical Education (CME) credits will be offered for in-person lectures, aiming to equip PCPs with the skills needed to address iNPH in low-income settings effectively

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A community health worker will assist PCP
Description: A community health worker will assist PCP to identify barriers and help overcome these barriers in order for patient to access iNPH care.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A community health worker will assist PCP
Description: A community health worker will assist PCP to identify barriers and help overcome these barriers in order for patient to access iNPH care.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A community health worker will assist PCP
Description: A community health worker will assist PCP to identify barriers and help overcome these barriers in order for patient to access iNPH care.
Study: NCT04702737

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tarlatamab
Description: Tarlatamab will be administered as an intravenous (IV) infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tarlatamab
Description: Tarlatamab will be administered as an intravenous (IV) infusion.
Study: NCT04845217

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peppermint oil
Description: Enteric coated peppermint oil taken by mouth three times daily for 8 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Coconut Oil
Description: Enteric coated coconut oil taken by mouth three times daily for 8 weeks
Study: NCT05641883

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CardiaMend with antiarrhythmic
Description: Pericardial patch with antiarrhythmic drug (amiodarone) topically applied
Study: NCT04078932

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Violence Prevention Conversation Script to Discuss Safely Navigating Police Encounters
Description: A conversation script to facilitate conversations on safely navigating police encounters as anticipatory guidance and violence prevention strategy. The conversation script will be created using expert recommendations from existing resources and using recommendations (determined from focus groups) from black male youth and their caregivers. The script will be patient-centered.
Study: NCT05857891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human erythropoietin injection
Description: Each subject in the test group received 40000iu of human erythropoietin intravenously

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9%NaCl
Description: Each subject in the control group was injected with an equal volume of 0.9%NaCl
Study: NCT04880330

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryo-Auriculotherapy
Description: 1 session of cryo-auriculotherapy with device with nitrous oxyde on 15 auricular points.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham comparator
Description: 1 session of cryo-auriculotherapy with device without nitrous oxyde on 15 auricular points.
Study: NCT05457582

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo plus high-intensity statin
Description: Administered subcutaneously using a spring-based prefilled 1.0 mL autoinjector/pen, Q2W, and oral administration of rosuvastatin (20 mg, once daily).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PCSK 9 Inhibitor plus high-intensity statin
Description: Administered subcutaneously using a spring-based prefilled 1.0 mL autoinjector/pen, Q2W, and oral administration of rosuvastatin (20 mg, once daily).
Study: NCT06177275

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Placement of BLX implants 2 mm sub-crestal i
Description: Placement of BLX implants 2 mm sub-crestal in single missing anterior or premolar teeth in the esthetic zone with immediate provisionalization via a straight emergence profile temporary crown on a temporary abutment.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Placement of BLX implants 2 mm sub-crestal i
Description: Placement of BLX implants 2 mm sub-crestal in single missing anterior or premolar teeth in the esthetic zone with immediate provisionalization via a straight emergence profile temporary crown on a temporary abutment.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Placement of BLX implants equicrestal
Description: Placement of BLX implants equicrestal in single missing anterior or premolar teeth in the esthetic zone with immediate provisionalization via a straight emergence profile temporary crown on a temporary abutment.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Placement of BLX implants equicrestal
Description: Placement of BLX implants equicrestal in single missing anterior or premolar teeth in the esthetic zone with immediate provisionalization via a straight emergence profile temporary crown on a temporary abutment.
Study: NCT05456750

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Intravascular laser irradiation of blood
Description: Low intensity intravenous laser irradiation of blood phototherapy is a method of a 632.8 nm red light penetrate into a vein through fiber and the brightness is 100 fold of the sun. The light accelerates blood and cells circulation in the human body, so that protein molecular structure would promote changes.
Study: NCT04589195

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Training
Description: The intervention includes four weeks of MT application use, accessed via phone or computer, consisting of 15-minute daily mindfulness practices 5 days a week.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness Training
Description: The intervention includes four weeks of MT application use, accessed via phone or computer, consisting of 15-minute daily mindfulness practices 5 days a week.
Study: NCT06314022

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile application for colonoscopy preparation instructions
Description: The APP will also consider the comorbidities and drugs of each patient. It can be adapted to the different types of laxative (4, 2 or 1 litre) and notify the need to discontinue anticoagulant and/or antiplatelet treatments by contacting with the primary care physician. Additionally, the application may ask short questions to the patient to control the laxative intake instruction. The user must confirm the appointment 48 hours in advance.
Study: NCT05306639

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: rehabilitation sessions using spinal magnetic stimulation or neuromodulation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: rehabilitation sessions using spinal magnetic stimulation or neuromodulation
Study: NCT05456750

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intravascular laser irradiation of blood
Description: Low intensity intravenous laser irradiation of blood phototherapy is a method of a 632.8 nm red light penetrate into a vein through fiber and the brightness is 100 fold of the sun. The light accelerates blood and cells circulation in the human body, so that protein molecular structure would promote changes.
Study: NCT05044221

Intervention type: OTHER
Intervention: Former ICU patient and caregiver workshops
Description: In depth interviews and workshops will be conducted with individuals enrolled in the study.

Intervention type: OTHER
Intervention: Health care professional workshops
Description: In depth interviews and workshops will be conducted with individuals enrolled in the study.
Study: NCT04728763

Intervention type: OTHER
Intervention: Protein profile
Description: Analysis of the protein content by proteomics of bronchoalveolar lavage

Intervention type: OTHER
Intervention: Protein profile
Description: Analysis of the protein content by proteomics of bronchoalveolar lavage
Study: NCT06228963

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triple therapy for eradication of Helicobacter Pylori and Orelabrutinib
Description: Triple therapy for H. pylori (oral administration for 2 weeks, followed by a 1-week break) plus Orelabrutinib for 8 weeks (or until progression, intolerable toxicity, death, or withdrawal from the study)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triple therapy for eradication of Helicobacter Pylori
Description: Triple therapy for H. pylori (oral administration for 2 weeks, followed by a 1-week break)
Study: NCT05327491

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: Oral Tablet
Study: NCT05117671

Intervention type: OTHER
Intervention: data collection to classify infection status
Description: Review of medical records of all selected cases (TKA/THA patients) to classify infection status according to different classifications (EBJIS, MSIS/ICM 2013, ICM 2018).
Study: NCT05346445

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluoxetine 20 MG
Description: Participants received non-hormonal treatment with fluoxetine.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Citalopram 20mg
Description: Participants received non-hormonal treatment with citalopram.
Study: NCT04991831

Intervention type: DEVICE
Intervention: Unilateral thalamotomy
Description: Unilateral thalamotomy using focused ultrasound for the treatment of medication-refractory tremor dominant idiopathic Parkinson's Disease.
Study: NCT06327230

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thoracic Epidural Analgesia
Description: Thoracic epidural analgesia is performed by a standardized anesthesia team. Patients are positioned in the lateral decubitus position, and routine disinfection is performed. The puncture site is selected at the T7-T9 level. When encountering sudden disappearance of resistance and appearance of negative pressure during needle advancement, it is determined that the needle has entered the epidural space. After confirming needle tip placement in the epidural space with a test dose, an epidural catheter is inserted approximately 3-5cm cephalad and securely fixed in place. The test dose consists of 3 mL of 1% lidocaine injection solution, administered to observe the level of anesthesia, confirming the effectiveness and safety of the epidural anesthesia. Subsequently, a maintenance regimen of 0.15% ropivacaine 250mL with 2.5mg of hydroma.
Study: NCT05439447

Intervention type: DIAGNOSTIC_TEST
Intervention: Patients scheduled for VFSS testing group
Description: Patients scheduled for VFSS testing, patient with voice.