TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05490004

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Violence, Evidence, Guidance, Action Project (VEGA) Education Intervention
Description: VEGA is a novel education intervention that has the potential to improve the preparation of healthcare and social service providers (HHSPs) to be able to effectively recognize and respond to intimate partner violence (IPV) and related forms of family violence, including child maltreatment (CM), in their clinical encounters. VEGA was developed based on systematic reviews and consultation with individuals belonging to 22 national healthcare and social service organizations, including the Royal College of Physicians and Surgeons of Canada. VEGA follows a competency-based framework and a participatory, encounter-based curriculum that includes four learning modules: (a) the epidemiology of IPV and CM; (b) strategies for safely recognizing and responding to (i) IPV and (ii) CM; and (c) principles for ensuring safe clinical encounters for IPV and CM discussions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Violence, Evidence, Guidance, Action Project (VEGA) Education Intervention
Description: VEGA is a novel education intervention that has the potential to improve the preparation of healthcare and social service providers (HHSPs) to be able to effectively recognize and respond to intimate partner violence (IPV) and related forms of family violence, including child maltreatment (CM), in their clinical encounters. VEGA was developed based on systematic reviews and consultation with individuals belonging to 22 national healthcare and social service organizations, including the Royal College of Physicians and Surgeons of Canada. VEGA follows a competency-based framework and a participatory, encounter-based curriculum that includes four learning modules: (a) the epidemiology of IPV and CM; (b) strategies for safely recognizing and responding to (i) IPV and (ii) CM; and (c) principles for ensuring safe clinical encounters for IPV and CM discussions.
Study: NCT04458415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traxi Panniculus Retractor (TPR)
Description: Surgeon uses the Traxi Panniculus Retractor (TPR) surgical retraction device to retract the panniculus during C-Section.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Silk Tape
Description: Surgeon uses silk tape to retract the panniculus during C-Section.
Study: NCT05626127

Intervention type: OTHER
Intervention: No interventions
Description: As this is a observational study, there are no interventions.
Study: NCT06128122

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intrarticular and subcutaneous dextrose injection with timed measurement of dextrose levels
Description: Step one: 30 mL of 12.5%/0.1% lidocaine will be injected into the knee using an inferomedial approach. Using ultrasound guidance, a 20-gauge 2-inch I.V. catheter will be placed in the suprapatellar pouch, by which samples of synovial fluid from the pouch will be withdrawn and analyzed for glucose level.~Step two: 3 mL of D5W will be injected into a marked spot on the back of the upper arm. A sensor/transmitter (Dexcom G7 Dexcom) is placed at the site of injection. The sensor/transmitter will begin providing dextrose levels at 5 minute intervals beginning one-half hour after placement of the sensor/transmitter, transmitted to a paired smart phone.
Study: NCT05308927

Intervention type: DRUG
Intervention: Norditropin
Description: Patients will be treated with commercially available Norditropin® according to routine clinical practice at the discretion of the treating physician.
Study: NCT06101199

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SHAM Acute Intermittent Hypercapnic Hypoxia
Description: Normoxia for the amount of time AIHH is delivered.
Study: NCT05308927

Intervention type: DRUG
Intervention: Norditropin
Description: Patients will be treated with commercially available Norditropin® according to routine clinical practice at the discretion of the treating physician.

Intervention type: DRUG
Intervention: Norditropin
Description: Patients will be treated with commercially available Norditropin® according to routine clinical practice at the discretion of the treating physician.
Study: NCT06392269

Intervention type: DIAGNOSTIC_TEST
Intervention: Tasso+SST
Description: Clinical evaluation of capillary blood samples collected using the Tasso+SST device for downstream analyte testing.
Study: NCT06101199

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SHAM Transcutaneous spinal cord stimulation
Description: Open-loop, continuous, high-frequency electrical stimulation at 150 Hz with a tolerable current amplitude of 0mA and a pulse width of 400 µsec,using a biphasic symmetric waveform.~Paired with Respiratory Resistance Training and Hand Grip Strength Training.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: SHAM Transcutaneous spinal cord stimulation
Description: Open-loop, continuous, high-frequency electrical stimulation at 150 Hz with a tolerable current amplitude of 0mA and a pulse width of 400 µsec,using a biphasic symmetric waveform.~Paired with Respiratory Resistance Training and Hand Grip Strength Training.
Study: NCT05256667

Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: RCT-SV
Description: Group 1- Endodontic treatment in a single visit using chemomechanical preparation and passive ultrasonic irrigation, followed by obturation and final restoration.

Intervention type: OTHER
Group type: OTHER
Intervention: RCT-TVWD
Description: Group 2- Endodontic treatment in two visits using chemomechanical preparation and passive ultrasonic irrigation, followed by intracanal dressing and temporary restoration for 7 days. After 7 days, an identical chemomechanical preparation on visit 2 will be performed, followed by obturation and final restoration.

Intervention type: OTHER
Group type: OTHER
Intervention: RCT-TVWOD
Description: Group 3- Endodontic treatment in two visits using chemomechanical preparation and passive ultrasonic irrigation, followed by temporary restoration for 2 days, without intracanal dressing. After 2 days, an identical chemomechanical preparation on visit 2 will be performed, followed by obturation and final restoration.
Study: NCT05295576

Intervention type: PROCEDURE
Intervention: non surgical periodontal therapy
Description: Scaling and root planing
Study: NCT05944926

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Activity Program (HAP)
Description: HAP, delivered over 6-8 sessions by non-specialist healthcare workers, has behavioural activation as the core psychological strategy along with other strategies such as problem-solving and activation of social networks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antidepressant medication (fluoxetine)
Description: Patients assigned to antidepressant medication will start on fluoxetine 20 mg/day and can be raised to 40 mg/day (the maximum mandated by treatment guidelines for primary care in India) at week 3 or 6 for patients who have yet to remit. Participants who do not tolerate fluoxetine can be switched to escitalopram at week 6 (10mg which can be titrated up to 20 mg).
Study: NCT06052280

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telerehabilitation exercise program
Description: After the outpatient intensive physical therapy program (common to both study arms), patients in the TrE group will continue with prescribed self-training at home through telerehabilitation, at least 3 times a week for 4 weeks. Each physical exercise session will consist of at least 5 minutes of aerobic warming-up, 35 minutes of specific high-intensity exercises for PD, and 5 minutes of aerobic cool-down.~The TrE arm will be supported by a telerehabilitation device which will be installed and tested at the patients' home immediately after the outpatient intensive program. The device will track any access and exercise duration, so that the physiotherapists will be able to remotely monitor both the actual duration of each session and their weekly frequency. One session per week will be directly and online supervised by a physiotherapist, while the other two will be recorded only.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home self-exercise program
Description: After the outpatient intensive physical therapy program (common to both study arms), patients in the HSE group will continue with prescribed self-training at home, at least 3 times a week for 4 weeks. Each physical exercise session will consist of at least 5 minutes of aerobic warming-up, 35 minutes of specific high-intensity exercises for PD, and 5 minutes of aerobic cool-down.~The HSE arm will be given a booklet containing detailed explanations and pictures of the assigned exercises, in order to guide them in the correct execution of the requested movements. Subjects in this group will be asked to fill in a training diary to keep track of the training sessions and their duration. Once a week a physiotherapist will contact patients to discuss possible problems encountered in performing the exercises and to help in solving them.
Study: NCT06198335

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Modified Perichondral Approach Thoracoabdominal Nerve block
Description: M-TAPA block will be performed to Group M-TAPA at the end of the surgery, using US (Vivid Q) while the patient is in the supine position After providing aseptic conditions, the high frequency linear US probe (11-12 MHz, Vivid Q) will be covered with a sterile sheath, and an 80 mm block needle (Braun 360°) will be used. The US probe will be placed in the sagittal plane where the midclavicular line intersects with the costal cartilage corresponding to the costochondral angle. Using the In Plane technique, the probe is gently pushed to visualize the lower part of the costochondral angle at the central level, advancing the block needle in the caudal-cranio direction, 5 ml of saline will be injected into the layer between the transverse abdominal muscle and the lower plane of the costal cartilage, and the block location will be confirmed. After the block location is confirmed, a total of 20 ml + 20 ml of 0.25% bupivacaine (total 40 ml for both sides) will be injected bilaterally

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transversus Abdominal Plane block
Description: TAP block will be performed to Group TAP at the end of the surgery, using US (Vivid Q) while the patient is in the supine position. After providing aseptic conditions, the high frequency linear US probe (11-12 MHz, Vivid Q) will be covered with a sterile sheath, and an 80 mm block needle (Braun 360°) will be used. USG will be placed transversely on the mid-axillary line between the iliac crest and subcostal planes. Using the In Plane technique, the block needle will be advanced into the fascial plane between the internal oblique and transversus abdominis muscles and the location will be confirmed by administering 5 ml of saline. The block needle will be advanced into the fascial plane between the internal oblique and transversus abdominis muscles and the location will be confirmed by administering 5 ml of saline.and than 20 ml of 0.25% bupivacaine (total 40 ml for both sides) will be injected bilaterally
Study: NCT06316752

Intervention type: OTHER
Intervention: Observational study
Description: It is an observational study involving non-invasive routine examinations without treatment, thus posing no additional risk to patients. This project does not involve the use of medications, medical techniques, or the market status of medical equipment.
Study: NCT05918679

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Effects of speech variability on speech motor learning
Description: This intervention will examine whether reducing normal variability of speech could improve error detection and speech motor learning. We will design training tasks to change subjects' speech variability. We will train subjects to decrease/decrease their speech variability. Upon completing the training tasks, subjects will complete a motor learning task.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Effects of error-detection training on speech motor learning
Description: This intervention will examine whether improving subjects' ability to detect and estimate auditory perturbation could improve speech motor learning. For this purpose, we will design training tasks to change subjects' estimation of the perturbation magnitude. After completing the training tasks, subjects will complete the motor learning task.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contributions of error awareness to speech motor learning
Description: This intervention will examine the contributions of error awareness to speech motor learning. Subjects will produce a target word while receiving perturbed auditory feedback with different magnitudes. Subjects will be trained to indicate the magnitude of the error they perceived with or without visual feedback.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhancing auditory-to-motor mapping with augmented visual feedback
Description: This intervention will determine the contributions of enhanced auditory-to-motor mappings to speech motor learning. We will design training tasks in which we will use visual feedback to provide feedback regarding subjects' accuracy of auditory-to-motor mapping.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Effects of enhanced auditory-motor awareness on speech motor learning
Description: In this intervention, subjects will be trained to control their articulators more accurately and be more aware of their articulators' position and their auditory consequences. After the training tasks, subjects will complete a motor learning task.
Study: NCT04581330

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DEKA SmartXide C02 laser
Description: One pass with a 1-mm spot density and a 60 micron depth will be performed followed by a 1-mm spot density and a 200 micron depth will be used
Study: NCT05990985

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitoxantrone hydrochloride liposome injection
Description: Mitoxantrone hydrochloride liposome injection (18 mg/m\^2) will be administered by intravenous infusion on day 1 in a 3-week treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RiTUXimab Injection
Description: RiTUXimab Injection (375 mg/m\^2) will be administered by intravenous infusion on day 0 in a 3-week treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamid
Description: Cyclophosphamid (750 mg/m\^2) will be administered by intravenous infusion on day 1 in a 3-week treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Vincristine (1.4 mg/m\^2，maximum dose 2mg ) will be administered by intravenous infusion on day 1 in a 3-week treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone
Description: Prednisolone (100mg/d) will be administered by intravenous infusion on day 1-5 in a 3-week treatment cycle.
Study: NCT05727098

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: injection of Bupivacaine 0.25% in ESPB

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride and dexmedetomedine
Description: injection of Bupivacaine 0.25% and dexmedetomedine in ESPB

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride and ketamine
Description: injection of Bupivacaine 0.25% and ketamine in ESPB
Study: NCT05919615

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic Acid 100 MG/ML
Description: Tranexamic Acid: 100 MG/ML Solution for injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: 0.9% sodium chloride normal saline
Study: NCT06465836

Intervention type: PROCEDURE
Group type: OTHER
Intervention: O, lreay suture
Description: bilateral uterine artery ligations as described by O- lreay technique in addition to standard conservative methods. Briefly two large vicryl stitches were passed using a large sized needle below and lateral to the lower edge of the uterine incision angle in anteroposterior direction and then redirected from back to the front through avascular window in the posterior leaf of the broad ligament just lateral to the uterine border taking care to avoid injury to bowel posteriorly or bladder/ureter anteriorly. The stitches were tied securely anteriorly

Intervention type: PROCEDURE
Group type: OTHER
Intervention: modified O, lreay suture
Description: 1. Pack Douglas- pouch with a towel.~2. Straight the used vicryl needle mostly no 1.~3. Try to compress and approximate anterior and posterior uterine walls.~4. Start from anterior to posterior 3- 4 cm medial to lateral uterine margin and then pass from posterior to anterior through avascular area in the broad ligament. And we repeat the procedure on the other side. We can repeat this method of uterine ligation at another different plane if needed.
Study: NCT05972369

Intervention type: OTHER
Intervention: 12-Week Tailored Exercise Intervention
Description: 12-week individually tailored exercise therapy program based on patient presentation. Supervised physiotherapy plus home exercise

Intervention type: OTHER
Intervention: 12-Week Tailored Exercise Intervention
Description: 12-week individually tailored exercise therapy program based on patient presentation. Supervised physiotherapy plus home exercise
Study: NCT04042844

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BRTX-100
Description: Hypoxic cultured mesenchymal stem cells (MSCs) from autologous bone marrow with autologous platelet lysate.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Sodium Chloride (0.9%) intravenous infusion preparation is a sterile and non-pyrogenic solution
Study: NCT05547724

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Virtual reality visit of the birth room, cesarean and pediatric hospitalization department: neonatology and neonatal intensive care
Study: NCT05481190

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Exercise Program
Description: Data collection tools were applied to the tele-exercise group and control group at the beginning of the study. For the tele-exercise group, by the researcher, Exp. A 6-week exercise program was created under the consultancy of a physiotherapist. Children who met the research criteria were asked to do these exercises for 20 minutes, 3 times a week for 6 weeks. The exercises were performed online with the researcher at the scheduled time one day a week, and by the children twice a week. On the days they exercised, diaries consisting of semi-structured questions were sent to the children's addresses by cargo and they were allowed to keep a diary. Phone calls were made once a week to provide motivation and increase compliance with exercise. A smart watch was sent to the children by cargo to increase motivation. The children were asked to fill in the follow-up form, which was sent via weekly google forms.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Exercise Program
Description: Data collection tools were applied to the tele-exercise group and control group at the beginning of the study. For the tele-exercise group, by the researcher, Exp. A 6-week exercise program was created under the consultancy of a physiotherapist. Children who met the research criteria were asked to do these exercises for 20 minutes, 3 times a week for 6 weeks. The exercises were performed online with the researcher at the scheduled time one day a week, and by the children twice a week. On the days they exercised, diaries consisting of semi-structured questions were sent to the children's addresses by cargo and they were allowed to keep a diary. Phone calls were made once a week to provide motivation and increase compliance with exercise. A smart watch was sent to the children by cargo to increase motivation. The children were asked to fill in the follow-up form, which was sent via weekly google forms.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Just observation
Description: Standard care was given to the children in the control group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Just observation
Description: Standard care was given to the children in the control group.
Study: NCT05786404

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PRIM-DJ2727 - FROZEN
Description: Patients with active UC will receive induction dose of 100 grams of stool via frozen retention enema, Fecal Microbiota Transplantation (FMT) product manufactured as PRIM-DJ2727-FROZEN administered in clinic. This consists of microbiota suspension from well-screened donors. Twice filtered fecal microbiota product diluted in saline to 500 mL containing 100g of study drug will be administered as frozen enema induction dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PRIM-DJ2727 - CAPSULES
Description: Patients with active UC will receive induction dose of 100 grams of stool in orally administered enteric-coated capsules Fecal Microbiota Transplantation (FMT) product manufactured as PRIM-DJ2727-CAPSULES.These capsules consists of microbiota from well-screened donors. The induction dose of enteric-coated capsules will be derived from 100 grams stool.
Study: NCT03515031

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Flow Nasal Cannula Oxygenation
Description: Delivery of humidified and heated (37ºC) high flow oxygen

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Venturi Mask Oxygenation
Description: delivery of high flow oxygen
Study: NCT04999527

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DISC-0974
Description: DISC-0974 is administered (IV infusion or Subcutaneous Injection) as a single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo is administered (IV infusion or Subcutaneous Injection) as a single dose
Study: NCT05621902

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Weekly symptom monitoring
Description: Patients randomized to the intervention arm will be invited to respond to a web-based weekly 11-item signs- and symptoms questionnaire
Study: NCT04948736

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Combined exercise and nutrition intervention
Description: Combined exercise and nutrition intervention for 12 weeks (an introductory phase 3 weeks, an expanded phase 3 weeks, and a maintenance phase 6 weeks).~Exercise intervention (each 60-min session) includes stretching, resistance exercise, and aerobic exercise according to protocol.~Nutritional intervention includes investigating dietary habits and calculate insufficient protein intake using Mini Nutritional Aseessment (MNA) and Korean Protein Assessment Tool (KPAT) to provide customized diet and high protein drink.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional medial care
Description: Conventional medical care service for 12weeks during intervention period. Usual care includes medical check-up and exercise and dietary counseling. They were given a brochure about exercise and protein-rich foods at their first visit.~The control group patients maintain their usual amount of activity and diet during the 6-month evaluation period. usual activity and dietary habits.