TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06607055

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood collection
Description: HLA-DR dosage, at the time of inclusion and once a week then
Study: NCT03895567

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C. Ceftriaxone rectal dosage form test formulation 2 (1 x 500mg)
Description: Rectal ceftriaxone formulations~Formulation 2 ceftriaxone 500mg + Na-CDC 125mg rectodispersible mannitol-based tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C. Ceftriaxone rectal dosage form test formulation 2 (1 x 500mg)
Description: Rectal ceftriaxone formulations~Formulation 2 ceftriaxone 500mg + Na-CDC 125mg rectodispersible mannitol-based tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C. Ceftriaxone rectal dosage form test formulation 2 (1 x 500mg)
Description: Rectal ceftriaxone formulations~Formulation 2 ceftriaxone 500mg + Na-CDC 125mg rectodispersible mannitol-based tablet
Study: NCT05468424

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tablet (iPad or android) based role-playing game
Description: The intervention is a tablet (iPad or android) based role-playing game called FarmVille. In FarmVille the player assumes the role of a farmer tasked with tending to crops and farm animals and using what is produced to craft goods which can be sold to expand the farm. The participant is required to play FarmVille for 5 or more hours a week for 8 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: tablet (iPad or android) based word puzzles and image puzzles
Description: This intervention is a selection of tablet (iPad or android) word puzzles and image puzzles. One word puzzle involves word making (i.e., making words from a set of random letters), and the other word searching (i.e., finding words on a grid of letters). One image puzzle is Flow Free, a game that requires the player to connect pairs of same coloured dots positioned on a grid ranging from 5x5 to 9x9. The other image puzzle is a jigsaw. The participant is required to play these games for 5 or more hours a week for 8 weeks.
Study: NCT06081179

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: Single dose of psilocybin (15mg), orally in form of capsules

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 3,4 Methylenedioxymethamphetamine
Description: Single dose of MDMA (100mg), orally in form of capsules

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylphenidate
Description: Single dose of methylphenidate (60mg), orally in form of capsules
Study: NCT04795596

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: secondary cytoreductive surgery
Description: resection of isolated recurrent ovarian carcinoma in platinum resistant disease

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: second line chemotherapy according to investigator's choice

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: second line chemotherapy according to investigator's choice
Study: NCT04819763

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical therapy
Description: Coordination training for lateral movement of the mandible (spatula exercise):~1. A wooden spatula is loosely placed between the teeth of the upper and lower jaw; the head must be aligned with the body axis; the exercise should be performed in front of a mirror.~2. The lower jaw moves to the left and back to the center with little contact to the spatula~3. The lower jaw moves to the right and back to the center under contact with the spatula~Training of the left lateral pterygoid muscle:~1. The left palm is placed on the left temple region~2. Right hand forms a fist and is placed on the tip of the right chin~3. Both arms are aligned parallel to the surface of the floor~4. The lower jaw is moved to the right against a moderate resistance of the fist = concentric muscle work~5. With measured force of the fist, the lower jaw is brought back to the center = eccentric muscle work (Right lateral pterygoid muscle training with opposite hands.)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Appliance therapy
Description: Upper and lower jaw impressions are registered by using an intraoral scanner. The arbitrary hinge axis position is determined using a face bow.~The stabilization appliance with anterior canine guidance is manufactured in the Lexmann laboratory in Dresden.~The stabilization appliance is incorporated by the dentist and the static and dynamic occlusion is checked. A tension-free fit of the appliance on the lower jaw is necessary. Additionally, equal contacts in the side teeth area and incisors guidance in the case of mandibular protrusion are checked visually and by using occlusion foil. During mandibular lateral movement only the canine guidance takes place and is also registered optically and by using occlusion foil.Interference contacts should be adjusted.~The patient is instructed to wear the stabilization appliance while sleeping. The wearing rhythm is described as intermittent. (three nights - wearing the appliance, one night - not wearing the appliance).
Study: NCT04621019

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-785F
Description: Treatment with study device.
Study: NCT04521972

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Room light/light bulb
Description: Room light will be ON/OFF or red light used in the room. Reducing/eliminating light in the room in the evening and night is expected to allow the natural release of melatonin, which is thought to promote uterine contractions in late pregnancy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Room light/light bulb
Description: Room light will be ON/OFF or red light used in the room. Reducing/eliminating light in the room in the evening and night is expected to allow the natural release of melatonin, which is thought to promote uterine contractions in late pregnancy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Room light/light bulb
Description: Room light will be ON/OFF or red light used in the room. Reducing/eliminating light in the room in the evening and night is expected to allow the natural release of melatonin, which is thought to promote uterine contractions in late pregnancy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Room light/light bulb
Description: Room light will be ON/OFF or red light used in the room. Reducing/eliminating light in the room in the evening and night is expected to allow the natural release of melatonin, which is thought to promote uterine contractions in late pregnancy.
Study: NCT05017597

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Exercises completed, and rate of perceived exertion (RPE) will be reviewed during \& after each exercise session. Exercises will be modified by either increasing or decreasing the intensity. Decisions will be made based RPE, physical symptoms \& any identified barriers or supports. Weeks 1, 3, 5, \& 7, Cancer-related fatigue (CRF) education will be assigned. During weeks 2, 4, 6, \& 8, CRF education will be reviewed and a plan for how to apply the information will be developed. Participant will be guided through 6 steps of problem solving to address one occupational performance problem identified by participant within Canadian Occupational Performance Measure. Goal \& action plan for the week will be shared with the participant electronically. At the beginning of each session, participant will describe progress on previous week action plan. Based on participant's response, either a new goal will be developed or the current one modified..
Study: NCT05639075

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peripheral vision
Description: A gait analysis test will be performed in each patient after cataract surgery to test peripheral vision
Study: NCT05833087

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Schema therapy
Description: 30 sessions of schema therapy. The therapy was developed by Jeffrey Young and others and encompasses elements from cognitive behavioral, psychodynamic, and gestalt therapies, as well as attachment theory.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Other psychotherapy
Description: In this arm, psychotherapy can be psychodynamic, cognitive behavioral, interpersonal or other evidence-based psychotherapies, aimed at changing cognitions, behavior, improve social relations and uncover unconstructive psychological patterns.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care package content
Description: The patient is offered prescription and monitoring of psychopharmacological treatment of up to 5 hours by a psychiatrist, when appropriate.~Additionally, patients have up to 3 hours of preparatory and diagnostic sessions and up to 4 hours of meetings with the participation of next-of-kin and/or collaboration partners in other public instances.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care package content
Description: The patient is offered prescription and monitoring of psychopharmacological treatment of up to 5 hours by a psychiatrist, when appropriate.~Additionally, patients have up to 3 hours of preparatory and diagnostic sessions and up to 4 hours of meetings with the participation of next-of-kin and/or collaboration partners in other public instances.
Study: NCT05011318

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baseline
Description: 5-min urban park video clip (Presented on a TV)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fatigue Manipulation
Description: 20-min 2-back task (Presented on a computer)
Study: NCT05835908

Intervention type: OTHER
Intervention: Phone questionnaire
Description: Patients will be contacted by the investigator to collect information regarding follow-up from the initial call to the Emergency call center until the patient is taken care of in the health care facility to which he/she has been admitted.
Study: NCT05093764

Intervention type: DEVICE
Group type: OTHER
Intervention: VIV TAVR with BVF using TCEP
Description: The insertion and retrieval of the SENTINEL device is performed at the time of the patients TAVR procedure in the same setting while they are sedated under moderate sedation or general anesthesia depending on the case. The device is inserted at the initiation of the procedure through 6F right radial artery access and the filters are positioned in the left common carotid artery and brachiocephalic artery. After deployment, the usual TAVR procedure is performed. At the conclusion of the procedure, the SENTINEL device is extracted and hemostasis is achieved at the radial access site in the usual fashion with patent hemostasis.
Study: NCT06423092

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music therapy songwriting
Description: Session 1: The goal of the first music therapy session is to know the parents musically and to provide information about song creation. This is achieved by exploring their favorite songs. Options for creating a song (original song or song parody) are presented and possibilities for creating lyrics are discussed.~Sessions 2-7: The structure of the song will be created and discussed with the parents. Parents will also be invited to include written messages from other family members in the lyrics if they wish. In each session, the developing welcome song is sung together with the parents, accompanied by the music therapist, who provides vocal or instrumental support.~The final sessions (Sessions 8-9) are dedicated to singing the final version of the song with the parents and their infant. Should the parents desire, a final recording of the song will also be made and the digital songbook will be created.
Study: NCT04602546

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BIS Complete Monitoring System
Description: The BIS™ EEG complete monitoring system is intended for use under the direct supervision of a licensed healthcare practitioner or by personnel trained in its proper use. The system and its associated parameters are intended for use on adult patients within a hospital or medical facility, providing patient care to monitor the state of the brain by data acquisition of EEG signals.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BIS Complete Monitoring System
Description: The BIS™ EEG complete monitoring system is intended for use under the direct supervision of a licensed healthcare practitioner or by personnel trained in its proper use. The system and its associated parameters are intended for use on adult patients within a hospital or medical facility, providing patient care to monitor the state of the brain by data acquisition of EEG signals.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BIS Complete Monitoring System
Description: The BIS™ EEG complete monitoring system is intended for use under the direct supervision of a licensed healthcare practitioner or by personnel trained in its proper use. The system and its associated parameters are intended for use on adult patients within a hospital or medical facility, providing patient care to monitor the state of the brain by data acquisition of EEG signals.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BIS Complete Monitoring System
Description: The BIS™ EEG complete monitoring system is intended for use under the direct supervision of a licensed healthcare practitioner or by personnel trained in its proper use. The system and its associated parameters are intended for use on adult patients within a hospital or medical facility, providing patient care to monitor the state of the brain by data acquisition of EEG signals.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BIS Complete Monitoring System
Description: The BIS™ EEG complete monitoring system is intended for use under the direct supervision of a licensed healthcare practitioner or by personnel trained in its proper use. The system and its associated parameters are intended for use on adult patients within a hospital or medical facility, providing patient care to monitor the state of the brain by data acquisition of EEG signals.
Study: NCT04204538

Intervention type: OTHER
Intervention: Dietary habits
Description: Data collected using food frequency questionnaire

Intervention type: OTHER
Intervention: Dietary habits
Description: Data collected using food frequency questionnaire

Intervention type: OTHER
Intervention: Risk factors associated with metabolic syndrome
Description: Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome

Intervention type: OTHER
Intervention: Risk factors associated with metabolic syndrome
Description: Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome
Study: NCT05097365

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin B12 + folic acid supplementation
Description: A 12 weeks parallel-group randomised controlled trial will be performed, in which erythematous lupus patients will complete a vitamin B12 and folic acid supplementation, in addition to the usual therapy. The dietary supplementation will be by capsules, which will content 400 mcg of folic acid and 2000 mcg of vitamin B12 each.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin B12 + folic acid supplementation
Description: A 12 weeks parallel-group randomised controlled trial will be performed, in which erythematous lupus patients will complete a vitamin B12 and folic acid supplementation, in addition to the usual therapy. The dietary supplementation will be by capsules, which will content 400 mcg of folic acid and 2000 mcg of vitamin B12 each.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo supplementation
Description: A 12 weeks parallel-group randomised controlled trial will be performed, in which erythematous lupus patients will complete a placebo supplementation.The placebo and vitamin B12 + folic acid supplement will be indistinguishable in terms of taste, smell, and appearance.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo supplementation
Description: A 12 weeks parallel-group randomised controlled trial will be performed, in which erythematous lupus patients will complete a placebo supplementation.The placebo and vitamin B12 + folic acid supplement will be indistinguishable in terms of taste, smell, and appearance.
Study: NCT04948892

Intervention type: OTHER
Intervention: Prescence of the father during cesarean section in general anesthesia
Description: The father is now present in the OR during cesarean section category 1, instead of waiting outside
Study: NCT05566184

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Modified pacifier
Description: In the experimental group, a modified pacifier will be given to the child during the procedure, and the data will be collected. In the application of vascular access to children, a) before the procedure (20 minutes before), b) just before the procedure (20. minutes), c) during the procedure (between 20.-40. minutes), and d) 20 minutes after the procedure (40. minutes). Physiological variables that will be evaluated four times, once for each application, will be observed on the monitor, the FLACC Pain Assessment Scale will be recorded by the researcher and salivary cortisol level will be measured.
Study: NCT04589663

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mometasone furoate
Description: Single inhaled dose of 100 µg mometasone furoate (MF) administered via Twisthaler® on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QMF149
Description: Single inhaled dose of QMF149 (75/40 µg indacaterol acetate/MF fixed dose combination) administered via Concept 1 device on Day 6-9

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of Care (Soc)
Description: Asthma therapy: budesonide and salbutamol being the most frequently used (excluding MF and indacaterol acetate)
Study: NCT06551376

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Ovarian Stimulation Start
Description: To compare ovarian response accordin to ovarian stimualtion start

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ovarian Stimulation Start
Description: To compare ovarian response accordin to ovarian stimualtion start
Study: NCT06006390

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CEA-targeted CAR-T cells
Description: Administration method: intravenous infusion； Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CEA-targeted CAR-T cells
Description: Administration method: intraperitoneal injection；Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.
Study: NCT05980572

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glenohumeral joint and subacromial space triamcinolone injections
Description: All patients will receive both glenohumeral joint and subacromial space injections. The injections will consist of a solution containing 1 ml of 40 mg/ml triamcinolone acetonide and 1 ml of 1% lidocaine in each site. The glenohumeral joint injection will be performed blindly using an anterior approach. The needle will be inserted medially to the head of the humerus, located approximately 1 cm lateral to the coracoid process, and directed posteriorly at a slight superior and lateral angle.~Patients will be educated on how to perform the 7 sets of frozen shoulder exercise. Subjects will be advised to perform all the exercises to a point that they may feel tightness but not painful and hold to the point for 2-3 seconds.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glenohumeral joint and subacromial space triamcinolone injections
Description: All patients will receive both glenohumeral joint and subacromial space injections. The injections will consist of a solution containing 1 ml of 40 mg/ml triamcinolone acetonide and 1 ml of 1% lidocaine in each site. The glenohumeral joint injection will be performed blindly using an anterior approach. The needle will be inserted medially to the head of the humerus, located approximately 1 cm lateral to the coracoid process, and directed posteriorly at a slight superior and lateral angle.~Patients will be educated on how to perform the 7 sets of frozen shoulder exercise. Subjects will be advised to perform all the exercises to a point that they may feel tightness but not painful and hold to the point for 2-3 seconds.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: App-assisted exercise
Description: Patients will be educated on how to perform the 7 sets of frozen shoulder exercise. Subjects will be advised to perform all the exercises to a point that they may feel tightness but not painful and hold to the point for 2-3 seconds. Then the APP group will suggest performing the exercise from APP education The APP intervention group will be guided through the exercises using the mobile app, while the conventional group will be provided with a printed pamphlet illustrating the exercises.. Each set exercise will have 10 repetitions and investigators recommend 4 sessions per day.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nonsteroidal anti-inflammatory drugs (aceclofenac)
Description: All patients will be prescribed two weeks of nonsteroidal anti-inflammatory drugs (aceclofenac) .

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nonsteroidal anti-inflammatory drugs (aceclofenac)
Description: All patients will be prescribed two weeks of nonsteroidal anti-inflammatory drugs (aceclofenac) .
Study: NCT04792424

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Regional citrate anticoagulation
Description: Starting RCA 4 mmol/L (adjust the rate by BFR)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Regional citrate anticoagulation
Description: Starting RCA 4 mmol/L (adjust the rate by BFR)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vasopressor
Description: Vasopressors such as Norepinephrine, dopamine, milrinone, dobutamine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vasopressor
Description: Vasopressors such as Norepinephrine, dopamine, milrinone, dobutamine

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Antibiotic
Description: Antibacterial agents deemed appropriate by physicians in the ICU

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotic
Description: Antibacterial agents deemed appropriate by physicians in the ICU

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Dialysis with continuous renal replacement therapy
Description: Prismaflex

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dialysis with continuous renal replacement therapy
Description: Prismaflex
Study: NCT06410313

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ChampioNIR Ridaforolimus Eluting Peripheral Stent System
Description: ChampioNIR implantation in Patients with Superficial Femoral Artery Disease and/or Proximal Popliteal Artery disease