TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05995587

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based cognitive therapy (MBCT)
Description: MBCT combines mindfulness meditation with cognitive behavioural therapy (CBT) elements to reduce or prevent recurrent major depressive disorders.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based cognitive therapy (MBCT)
Description: MBCT combines mindfulness meditation with cognitive behavioural therapy (CBT) elements to reduce or prevent recurrent major depressive disorders.
Study: NCT05022316

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CDS Tool Access
Description: Clinics receiving the intervention will have access to EHR-based CDS tools designed to support social risk-informed care. Prior to tool activation in participating community health centers (CHCs), clinic staff members will be oriented to the CDS tools by an EHR trainer (either on-site or remotely).
Study: NCT05077904

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Staccato alprazolam
Description: Route of administration: Inhalation~Participants will receive one dose of Staccato alprazolam during the Treatment Period.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Route of administration: Inhalation~Participants will receive one dose of placebo during the Treatment Period.
Study: NCT05266482

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Personal report
Description: In the intervention group, in addition to receiving the usual care, patients will receive personal reports on multiple time points. These reports include feedback on their PROs including reference scores of patients who previously underwent total knee replacement surgery.
Study: NCT05887557

Intervention type: OTHER
Group type: OTHER
Intervention: Active Referral
Description: As an implementation science study, all clinical intervention components will be delivered as part of routine clinical care at participating clinical sites. Clinicians and staff at referral sites throughout San Francisco and Alameda counties (emergency departments, psychiatric emergency services, community clinics, care navigation and case management programs, and community-based services) will refer eligible patients who are out of care and are interested in linking to drop-in and/or mobile care services at one of the study sites. Clinical referrals will include basic patient information and contact/locator information to facilitate linkage to care. Referrals will be site-specific based on the site where the patient is interested in accessing care.
Study: NCT05714540

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
Description: The Effect of Oropharyngeal Pack Soaked with Ketamine or Magnesium Sulphate on Post Operative Sore Throat after Nasal Surgeries

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
Description: The Effect of Oropharyngeal Pack Soaked with Ketamine or Magnesium Sulphate on Post Operative Sore Throat after Nasal Surgeries

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
Description: The Effect of Oropharyngeal Pack Soaked with Ketamine or Magnesium Sulphate on Post Operative Sore Throat after Nasal Surgeries
Study: NCT05654064

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remifentanil-dexmedetomidine
Description: Compare adequacy of remifentanil-dexmedetomidine sedation protocols in pregnant patients undergoing minimally invasive fetoscopic procedures.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine-fentanyl
Description: Compare adequacy of dexmedetomidine-fentanyl sedation protocols in pregnant patients undergoing minimally invasive fetoscopic procedures.
Study: NCT05793866

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BUTEYKO RESPIRATORY TECHNIQUE
Description: Buteyko Breathing Technique In recent years, breathing exercises have been used as one of the non-pharmacological, alternative and/or complementary approaches in the management of many chronic diseases and conditions. Buteyko Breathing Technique (BST), Russian Dr. It was developed by Konstantin Buteyko in the 1950s. Dr. Buteyko evaluates the normal respiration over carbon dioxide, the respiratory holding time used in the technique is defined as a control pause, and this value shows the body's oxygenation and carbon dioxide tolerance. BST is a technique performed only through the nose, which includes respiratory control and respiratory hold after inhalation.
Study: NCT04769232

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EG-760Z endoscope by Fujifilm
Description: Within a single endoscopic procedure under propofol sedation, images of the esophageal wall will be acquired and biopsies will be taken. All patients will be examined using the EG-760Z endoscope by Fujifilm.~In all patients as part of the clinical routine 4 biopsies of the proximal and 4 biopsies of the distal esophagus will be taken.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EG-760Z endoscope by Fujifilm
Description: Within a single endoscopic procedure under propofol sedation, images of the esophageal wall will be acquired and biopsies will be taken. All patients will be examined using the EG-760Z endoscope by Fujifilm.~In all patients as part of the clinical routine 4 biopsies of the proximal and 4 biopsies of the distal esophagus will be taken.
Study: NCT05534568

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Parent-Child Assistance Program
Description: Case managers work closely with mothers over the course of three years, meeting the mothers in their own homes when possible, to help them to set goals and take advantage of available resources.
Study: NCT04712136

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MRI
Description: MRI cardiac

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: MRI
Description: MRI cardiac
Study: NCT05454020

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XG004
Description: XG004 gel in two concentrations (5% and 10%) will be applied topically once-daily, twice-daily or three times daily in a designated area of the study knee.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo gel will be applied topically once-daily, twice-daily or three times daily in a designated area of the study knee.
Study: NCT05691413

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Other: Product X facial cleanser
Description: Product X facial cleanser contain olive oil, virgin coconut oil, butylene glycol and hyaluronic acid
Study: NCT04814589

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ezetimibe tablets
Description: The subjects randomly received single oral administration of ezetimibe tablets 10 mg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ezetimibe tablets(Ezetrol ®)
Description: The subjects randomly received single oral administration of ezetimibe tablets 10 mg.
Study: NCT05430802

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furmonertinib+cisplating/pemetrexed
Description: Furmonertinib 80mg/d for 9 weeks and cisplating75mg/m2 d1 iv + pemetrexed 500mg/m2 d1 iv in 21-day cycles for 3 cycles
Study: NCT04269720

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biofeedback
Description: They will also be taught how to use the biofeedback app and Inner Balance device. Additionally, they will also be educated on the principles of biofeedback and its benefits and taught how to maximize HRV by using self-regulation breathing techniques, guided imagery, and/ or self-talk.They will be given an Inner Balance device, which is an ear sensor that connects to an apple device that measures heart rate variability (HRV) and gives them access to an app that is designed to help them improve their HRV. They will be asked to use this device daily for 10 mins for the duration of the 8-week intervention. Patients and the research coordinator will have access to all of their sessions and results. The research coordinator will monitor compliance via the Heartcloud associated with their device and encourage adherence throughout the 8-week biofeedback intervention.
Study: NCT04826471

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DermoRelizema ecofoam
Description: DermoRelizema ecofoam, class II a medical device, topical compact mousse, to be applied 2 times per day during the 42 days of study duration
Study: NCT03713671

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: gait analysis
Description: Computerized gait analysis system will use to evaluate spatio-temporal gait parameters

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: gait analysis
Description: Computerized gait analysis system will use to evaluate spatio-temporal gait parameters
Study: NCT06039319

Intervention type: OTHER
Intervention: Physical activity
Description: 30 minute bout of moderate intensity physical activity performed on a treadmill

Intervention type: OTHER
Intervention: Physical activity
Description: 30 minute bout of moderate intensity physical activity performed on a treadmill
Study: NCT05497765

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Silibinin extract, mixed power of pueraria, schisandra and salvia miltiorrhiza
Description: Take 4 tablets with warm water twice a day

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Silibinin extract
Description: Take 4 tablets with warm water twice a day

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Take 4 tablets with warm water twice a day
Study: NCT06504862

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zongertinib
Description: Zongertinib
Study: NCT06092528

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inspiratory muscle training
Description: Inspiratory muscle training will be performed with Power Breathe®. Inspiratory muscle training will be given to the training group, starting from 50% of the MIP, and 2 sessions/day, 15 minutes/session. Patients will be asked to check breathing for 4-5 breaths after 8-10 consecutive breathing cycles. The patient will continue this cycle for 15 minutes.
Study: NCT06504862

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zongertinib
Description: Zongertinib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dabigatran-etexilate
Description: Dabigatran-etexilate
Study: NCT06092528

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Upper extremity aerobic exercise training
Description: Upper extremity aerobic exercise training will be performed 3 days/week, 1 session/day, 15 min/session using arm ergometer device accompanied by a physiotherapist. Aerobic exercise training workload will be 60-80% of maximal heart rate. In this study, the perception of dyspnea will be between 3-4, arm fatigue and general fatigue perception will be between 5-6, warm-up and cool-down periods will be 5 minutes, and pedaling speed will be 40-50 rev/min, according to MBS.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lower extremity aerobic exercise training
Description: Lower extremity aerobic exercise training will be performed 3 days/week, 1 session/day, 15 minutes/session using the treadmill device, accompanied by a physiotherapist. Aerobic exercise training workload was set at 60-80% of maximal heart rate, dyspnea perception according to MBS was between 3-4, arm fatigue and general fatigue perception was between 5-6, and warm-up and cool-down periods were 5 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistant exercise training
Description: Upper and lower additional limb strengthening training will be performed 3 days/week, 1 session/day, 10 repetitions/sessions from the first day by using bullion weights in the presence of a physiotherapist. The upper extremity strengthening program will consist of a progressive exercise program to strengthen the shoulder flexors and abductors, and the lower extremity strengthening program to strengthen the knee extensors. The training workload will be increased progressively. For strength training, the workload will be adjusted so that the perception of fatigue is between 4 and 6 according to MBS.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Thoracic expansion exercises
Description: The control group will be asked to do thoracic expansion exercises seven days/week and 120 pieces/day for six weeks.
Study: NCT06504862

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin
Description: Rosuvastatin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin hydrochloride
Description: Metformin hydrochloride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furosemide
Description: Furosemide
Study: NCT06028126

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intermittent Superficial Parasternal Intercostal Plane Block - Experimental
Description: Catheter insertion will be performed by an anesthesiologist with regional block training immediately following skin closure in the operating room. Catheters will be inserted under ultrasound guidance, in a sterile fashion, with a high-frequency linear transducer which will be placed 1 cm lateral to the sternal border in the longitudinal plane in order to view the T4-T5 intercostal space. A Tuohy needle will be used to enter the superficial parasternal intercostal plane, with saline being injected to help visualize the plane between the pectoralis major and intercostal muscles. Subsequently, the catheters will be advanced into the plane, and secured on the skin.~Following initial bolus dosing at the time of catheter placement (20 mL 0.2% ropivacaine), intermittent boluses of 10 mL 0.2% ropivacaine per side will be delivered via catheters q6-8 hours for 48 hours post-catheter insertion.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Intermittent Superficial Parasternal Intercostal Plane Block - Sham
Description: Catheter insertion will be performed by an anesthesiologist with regional block training immediately following skin closure in the operating room. Catheters will be inserted under ultrasound guidance, in a sterile fashion, with a high-frequency linear transducer which will be placed 1 cm lateral to the sternal border in the longitudinal plane in order to view the T4-T5 intercostal space. A Tuohy needle will be used to enter the superficial parasternal intercostal plane, with saline being injected to help visualize the plane between the pectoralis major and intercostal muscles. Subsequently, the catheters will be advanced into the plane, and secured on the skin.~Following initial bolus dosing at the time of catheter placement (20 mL 0.9% Saline), intermittent boluses of 10 mL 0.9% Saline per side will be delivered via catheters q6-8 hours for 48 hours post-catheter insertion.
Study: NCT06420245

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Orion TM Amniotic Membrane Allograft
Description: The intervention is a sterile allograft made from dehydrated extracellular matrix, designed to promote wound healing by providing a reliable and protective wound covering. Amniotic membranes are hypothesized to promote healing in open wounds by serving as a scaffold to support native tissue ingrowth, encouraging angiogenesis, and limiting microbial spread.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC)
Description: Standard wound care entails surgical debridement as needed to remove all non-viable tissue, screening for infection and probing of the wound for bone, weekly application of a collagen alginate primary dressing, and off-loading using a removable diabetic offloading cam-walker or total contact cast.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care (SOC)
Description: Standard wound care entails surgical debridement as needed to remove all non-viable tissue, screening for infection and probing of the wound for bone, weekly application of a collagen alginate primary dressing, and off-loading using a removable diabetic offloading cam-walker or total contact cast.
Study: NCT05462873

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: QEQ278
Description: Intravenous dosing of QEQ278
Study: NCT05679453

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lornoxicam 8 Mg Oral Tablet
Description: Lornoxicam is a oxicam grup non-steroid antiinflamatuar drug

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lornoxicam 8 Mg Oral Tablet
Description: Lornoxicam is a oxicam grup non-steroid antiinflamatuar drug
Study: NCT05276102

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Emollient cream
Description: Commercially available emollient cream

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Emollient cream
Description: Commercially available emollient cream

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Emollient cream
Description: Commercially available emollient cream
Study: NCT06130085

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Partially hydrolyzed formula
Description: Partially hydrolyzed formula given as the milk supplement for cow milk allergy patients after 6 months of strict elimination diet
Study: NCT05163262

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sexuality questionnaire
Description: Questionnaire evaluating the sexuality of head trauma victims by comparing their sexual focus, the quality of their relationship, their self-esteem, their mood before the trauma to their current situation
Study: NCT05767593

Intervention type: DEVICE
Intervention: Wearing Samsung smartwatch and filling out daily surveys
Description: Participants will wear a Samsung smartwatch and fill out daily surveys about their mood and depressive symptoms.

Intervention type: DEVICE
Intervention: Wearing Samsung smartwatch and filling out daily surveys
Description: Participants will wear a Samsung smartwatch and fill out daily surveys about their mood and depressive symptoms.
Study: NCT05965765

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Total knee arthroplasty
Description: who got total knee arthroplasty because of osteoarthritis

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Total knee arthroplasty
Description: who got total knee arthroplasty because of osteoarthritis

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Total knee arthroplasty
Description: who got total knee arthroplasty because of osteoarthritis

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: osteoarthritis without surgery
Description: who has osteoarthritis and didn't get any surgery

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: osteoarthritis without surgery
Description: who has osteoarthritis and didn't get any surgery

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: osteoarthritis without surgery
Description: who has osteoarthritis and didn't get any surgery
Study: NCT06109753

Intervention type: PROCEDURE
Intervention: Robotically Assisted Laparoscopic Surgery
Description: robotically assisted surgeries of about 60-minute duration with additional 30 min for preparing with the measurement equipment before surgery and 15 post evaluation of the corresponding surgery

Intervention type: PROCEDURE
Intervention: Conventional Laparoscopic Surgery
Description: conventional surgeries of about 60-minute duration with additional 30 min for preparing with the measurement equipment before surgery and 15 post evaluation of the corresponding surgery
Study: NCT06304298

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.9% Sodium Chloride Injection
Description: After spinal anesthesia, the ultrasound-guided iPACK block will be performed with 20ml of 0.9% sodium chloride

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine 0.2% Injectable Solution
Description: After spinal anesthesia, the ultrasound-guided iPACK block will be performed with 20ml of 0.2% ropivacine
Study: NCT06532370

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contingency Managment
Description: If the sample be methamphetamine negative, participant will be positively reinforced and offered incentives. Participants immediately draw the reinforcement slip of paper to receive a prize from a selection kept on-site. Approximately, half of the slips offer written praise (e.g. great job!). The other half of slips are then divided between low value (e.g. food gift cards, bus passes), medium value (e.g. prepaid cell phone, clothing gift cards), and a few large value rewards (e.g. iPad, jewelry). Should the sample be positive for methamphetamine, no reinforcement and/or incentive to be provided. Participant will be encouraged to continue to participate in CM program and follow-up on the next CM date.
Study: NCT05882058

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764532, formulation 1
Description: BI 764532, formulation 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764532, formulation 1
Description: BI 764532, formulation 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764532, formulation 2
Description: BI 764532, formulation 2

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764532, formulation 2
Description: BI 764532, formulation 2
Study: NCT05965765

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: control group
Description: healthy people
Study: NCT06439836

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tumor biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Emavusertib
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET
Study: NCT06360796

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [(14)C]ADC189
Description: Each subject take a single oral dose of about 45 mg (about 100 μCi) \[(14)C\]ADC189 on Day 1 of the study, and be observed by 504 hours.
Study: NCT05810129

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: concentric-eccentric strength training
Description: Concentric-eccentric cross training in a 6-week immobilization period + 12-week standard kinesic therapy (2 times a week)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eccentric strength training
Description: Eccentric cross training in immobilization period of 6 weeks + Standard kinesic therapy of 12 weeks (2 times a week)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: standard physical therapy
Description: Men with clavicle fracture immobilized for 6 weeks + standard physical therapy for 12 weeks
Study: NCT05165160

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Pre- and postoperative blood sample