Study: NCT04726878

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: Ultrasound-guided the erector spinae plane block with 0.375% ropivacaine, 0.4 mL per KG, up to 40 mL (maximum dose).

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham block
Description: Ultrasound-guided the erector spinae plane block with 0.9% saline, 0.4 mL per KG, up to 40 mL (maximum dose).

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: General anesthesia
Description: Standard general anesthesia. The induction with fentanyl, 1-3 mcg per KG; propofol, 1.5-2 mg per kg. Then, the laryngeal mask airway will be inserted. Patients with the risk of aspiration will be intubated using rocuronium or suxamethonium.~The maintenance with oxygen/air mixture, sevoflurane, and fentanyl.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General anesthesia
Description: Standard general anesthesia. The induction with fentanyl, 1-3 mcg per KG; propofol, 1.5-2 mg per kg. Then, the laryngeal mask airway will be inserted. Patients with the risk of aspiration will be intubated using rocuronium or suxamethonium.~The maintenance with oxygen/air mixture, sevoflurane, and fentanyl.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: General anesthesia
Description: Standard general anesthesia. The induction with fentanyl, 1-3 mcg per KG; propofol, 1.5-2 mg per kg. Then, the laryngeal mask airway will be inserted. Patients with the risk of aspiration will be intubated using rocuronium or suxamethonium.~The maintenance with oxygen/air mixture, sevoflurane, and fentanyl.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Patient-controlled analgesia
Description: All patients will receive a PCA pump with oxycodone (1 mg/mL, 5-minute interval) after transfer to PACU (post-anesthesia care unit)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patient-controlled analgesia
Description: All patients will receive a PCA pump with oxycodone (1 mg/mL, 5-minute interval) after transfer to PACU (post-anesthesia care unit)

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Patient-controlled analgesia
Description: All patients will receive a PCA pump with oxycodone (1 mg/mL, 5-minute interval) after transfer to PACU (post-anesthesia care unit)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxycodone
Description: Intravenous oxycodone will be administered about 30 minutes before the end of the surgery at a dose of 0.1 mg/KG. Additional 2 doses can be given if pain on the visual analog scale will be higher than 40.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone
Description: Intravenous oxycodone will be administered about 30 minutes before the end of the surgery at a dose of 0.1 mg/KG. Additional 2 doses can be given if pain on the visual analog scale will be higher than 40.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Oxycodone
Description: Intravenous oxycodone will be administered about 30 minutes before the end of the surgery at a dose of 0.1 mg/KG. Additional 2 doses can be given if pain on the visual analog scale will be higher than 40.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: paracetamol
Description: intravenous paracetamol will be used (1.0 gram), up to 4 grams per day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: paracetamol
Description: intravenous paracetamol will be used (1.0 gram), up to 4 grams per day

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: paracetamol
Description: intravenous paracetamol will be used (1.0 gram), up to 4 grams per day