TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06786000

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Anodal tDCS combined with mCIMT
Description: 20 minutes of anodal tDCS followed by 1 hour of the mCIMT program. The anodal electrode will be placed over the ipsilesional M1 (primary motor cortex, C3 or C4 according to EEG 10/20 system), and the cathodal electrode over the contralateral supraorbital area (Fp1 or Fp2) ). Leading to subthreshold depolarization to promote cortical excitation. And twelve different oriented tasks will be used during the 1-hour training period.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cathodal tDCS combined with mCIMT
Description: 20 minutes of cathodal tDCS followed by 1 hour of the mCIMT program. the cathodal electrode will be placed over the contralesional M1, and the anodal electrode over the contralateral supraorbital area (Fp1 or Fp2). leading to subthreshold polarization to promote cortical inhibition. And twelve different oriented tasks will be used during the 1-hour training period.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bihemispheric tDCS combined with mCIMT
Description: 20 minutes of Bihemispheric tDCS followed by 1 hour of the mCIMT program. the cathodal electrode will be placed over the primary motor cortex (M1) of the contralesional hemisphere and the anodal electrode will be placed above the ipsilateral M1 position (C3 or C4 positions, according to the 10/20 EEG system). And twelve different oriented tasks will be used during the 1-hour training period.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham tDCS combined with mCIMT
Description: 20 minutes of sham tDCS followed by 1 hour of the mCIMT program. the same stimulation place and parameters will be used as in the anodal group. However, after 30 seconds of stimulation, the stimulator will switch off. This provides the participants with the experience of the initial itchy sensation that occurs during tDCS, which is required for efficient masking. And twelve different oriented tasks will be used during the 1-hour training period.
Study: NCT06783452

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Clinical Pilates Session:~Each clinical Pilates movement will have three difficulty levels: beginner, intermediate, and advanced. The progression criteria for increasing difficulty will be determined by the prevention of compensatory movements, the ability to activate target muscles, achieving more controlled movements during exercise, and maintaining a more stable posture. This program will include standard hip-focused as well as full-body clinical Pilates movements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Conventional Therapeutic Exercise Program:~The Conventional Therapeutic Physiotherapy Exercise Program will consist of strengthening exercises for the hip flexors, extensors, abductors, and adductors, as well as the knee flexors and extensors. Additionally, stretching exercises for the hip flexors, extensors, abductors, and adductors, as well as the knee flexors and extensors, will be included. Stretching exercises will be performed at a pain-free point where tension is felt, holding for 10-30 seconds to achieve a total duration of 60 seconds per muscle group. These exercises will represent standard hip-targeted exercises.~During the exercises, patients will be asked to rate their perceived exertion using the BORG scale (0-10). When the difficulty level reaches 5-6 points, progression will first be achieved by increasing the number of sets, followed by the use of resistance bands.
Study: NCT06788132

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Cranberry products
Description: One capsule of cranberry extract 100mg equivalent 36 mg, hibiscus extract 20 mg, vitamin C 500 mg with lactobacillus 200 MU per day for 10 days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Starch one capsule per day for 10 days
Study: NCT06307405

Intervention type: DIAGNOSTIC_TEST
Intervention: next generation sequencing
Description: All the enrolled patients had undergone fiberbronchoscopy and sputum had been retained. The collected alveolar lavage fluid and sputum were examined for mNGS and routine etiology, respectively
Study: NCT05391880

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEBT-503 20mg
Description: BEBT-503 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEBT-503 40mg
Description: BEBT-503 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEBT-503 80mg
Description: BEBT-503 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEBT-503 120mg
Description: BEBT-503 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEBT-503 180mg
Description: BEBT-503 capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo 20mg
Description: placebo capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo 40mg
Description: placebo capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo 80mg
Description: placebo capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo 120mg
Description: placebo capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo 180mg
Description: placebo capsule
Study: NCT06784232

Intervention type: PROCEDURE
Intervention: BARP
Description: deep layers of collagen, medium-superficial heterologous bone graft, superficial collagen layer

Intervention type: PROCEDURE
Intervention: Modified Periosteal Inhibition Technique
Description: Cortical lamina stabilized with human fibrin glue to preserve the buccal wall of the socket. The socket was then filled with collagen.
Study: NCT06782815

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Acupuncture
Description: acupuncture Baihui, Sishencong ; acupuncture bilateral Qimen, Zhangmen, Hegu, Taichong, reinforcing and reducing, until the acid swelling is obvious,stopped ferforming acupuncture, the needle was retained for 30 min.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: （1）Acupuncture bilateral Tianrong points, obliquely 45 ± 5 ° backward, 1-1.5 inch deep, reinforcing and reducing horizontally, and stop the needle when the auricle has a heat sensation ; （2）Acupuncture at bilateral Tianyou points, pointing to the tip of the nose, with a depth of 0.5-1 inches, flat reinforcing and reducing, until the sense of soreness and distension obviously stops, and the needle is retained for 30 minutes.
Study: NCT06786637

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nociceptin Receptor Antagonist (LY-2940094)
Description: Participants in the experimental arms will receive 40 mg of the nociceptin receptor antagonist LY-2940094. Peak concentrations are achieved 2-4 hours post-administration.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DS8R Biphasic Constant Current Stimulator
Description: As part of the fear conditioning task, electrotactile stimulation will be used. The aversive stimulus is delivered in the form of a mild half-second stimulation to the ankle, calibrated to a subjective threshold that is uncomfortable but not painful. This stimulation is delivered by Digitimer DS8R Constant Current Stimulator (Digitimer North America, LLC. Ft. Lauderdale, FL). This model has been safely implemented in studies within McLean Hospital and Massachusetts General Hospital.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: DS8R Biphasic Constant Current Stimulator
Description: As part of the fear conditioning task, electrotactile stimulation will be used. The aversive stimulus is delivered in the form of a mild half-second stimulation to the ankle, calibrated to a subjective threshold that is uncomfortable but not painful. This stimulation is delivered by Digitimer DS8R Constant Current Stimulator (Digitimer North America, LLC. Ft. Lauderdale, FL). This model has been safely implemented in studies within McLean Hospital and Massachusetts General Hospital.
Study: NCT06784856

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PICC AR APP
Description: This study utilized Vuforia software and Unity 2022 LTS as the primary development platforms to create an AR-Enhanced and Game-Assisted Teaching curriculum. The designed PICC AR Exploration APP was developed for both iOS and Android platforms. The PICC-related content was based on the 8th Edition of the Infusion Therapy Standards of Practice published by the Infusion Nurses Society (INS) in 2021 and the 2022 Clinical Guidelines for Vascular Access Devices.~The required items for PICC care procedures were photographed and used to create 3D object elements and animations for developing AR scenarios and interactive gaming elements. The design and content of the PICC AR Exploration APP are described as follows:~Game Design Concept:~The PICC AR Exploration APP includes a learning unit system and a quiz unit system:~Learning Unit System Content:~Topic 1: Updates to guidelines and an introduction to clinical applications. Topic 2: PICC catheter care, dressing change steps, and techni

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Classroom Teaching and Case Sharing
Description: Introduction to Updated CVAD-PICC Guidelines and Clinical Applications~PICC Catheter Care Management of Common PICC-Related Complications Case Sharing on PICC Complication Management: Researchers
Study: NCT06784388

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Deep Brain Stimulation(DBS)
Description: During the DBS treatment phase, the DBS device will apply electrical stimulation to the patient's target brain regions using a specific strategy, and if the efficacy of this phase is not satisfactory, electrical stimulation will continue to be applied during the efficacy observation phase after DBS shutdown.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: SEEG intraoperative experiment: patients will be implanted with microelectrodes and connected to an electrophysiological recorder under local anesthesia. Intraoperative neurophysiological baseline will be recorded for 5 minutes, and esketamine will be injected intravenously at a dose of 0.5 mg/kg, and neurophysiological recordings will be continued for 15 minutes to observe the neuronal electrophysiological changes in various brain regions and target points.
Study: NCT06786728

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: frusemide
Description: in this group we use vexus score to asses decongestion in comparison to lung ultrasound in other group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: frusemide
Description: in this group we use vexus score to asses decongestion in comparison to lung ultrasound in other group
Study: NCT06784661

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lipid-Based Artificial Tear
Description: This intervention consists of a lipid-based artificial tear formulation containing mineral oil and hydroxypropyl guar. It is designed to enhance the tear film's lipid layer and improve ocular surface stability. Participants in this group will receive a single drop in each eye, and corneal aberrations will be measured at baseline and 15 minutes after instillation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Non-Lipid Artificial Tear
Description: This intervention consists of a non-lipid artificial tear formulation containing hydroxypropyl guar. It is intended to stabilize the aqueous layer of the tear film and maintain optical quality. Participants in this group will receive a single drop in each eye, and corneal aberrations will be measured at baseline and 15 minutes after instillation.
Study: NCT06783803

Intervention type: DIAGNOSTIC_TEST
Intervention: Linkage Analysis
Description: WES-Linkage analysis in families with FTAAD in follow-up in an Italian reference centre for genetic aorthopathies
Study: NCT06783790

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avapritinib, azacitidine, Venetoclax
Description: A: Induction therapy period: After patients were screened and enrolled, they began to receive 1-2 cycles of induction therapy, and the specific administration regimen was as follows: Avapritinib 100mg po qd D1-D14, azacitidine 35mg/m2 ih D1-D5, Venetoclax 100mg po qd D1-D14. The 28-day cycle was followed by curative effect evaluation at the end of each cycle. Patients who achieved complete remission entered the consolidation treatment stage.~B: Consolidation therapy period: Patients who achieved complete remission after 1-2 cycles of induction therapy continued to receive avapritinib 100mg/d po. monotherapy for consolidation therapy, with a cycle of 28 days and a total of 4 cycles
Study: NCT06786143

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Esmadem Education Model
Description: Application Application of the Research The implementation of the research was done in 3 steps.~Step 1: In the first stage of the research, after the risky pregnant women who come to the polyclinic are informed about the study, the participants who agree to participate and meet the criteria for inclusion in the research will be determined by randomization. After the pregnant women assigned to the training or control group sign the voluntary consent form and their consent is obtained, Personal InformationForm, Mishel Uncertainty in Illness Scale Depression-Anxiety-Stress Scale Depression-Anxiety-Stress Scale (DASÖ-21) scales will be applied. After the first interviews, the study group will be informed about the sessions and the training will start via zoom.~In educational sciences, since the number of groups is between 2-20 people in the acquisition of target behaviors at the conceptual level, two training groups will be created and 15 pregnant women will be in the first group, 15 preg
Study: NCT06549153

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education Content
Description: Participants will be offered group based education sessions expected to last 90 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Focus Group
Description: Participants will attend via Zoom
Study: NCT05868239

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aerosol box
Description: The aerosol box is a transparent, plastic cube covering the patient's head and shoulders, with circular access ports on the front of the box allowing for access to manage the airway. An additional four access holes (i.e. two on either side of the box) allow for airway assistants to access the patient airway.
Study: NCT05665569

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Flourish HEC, which contains BioNourish
Description: The Flourish HEC vaginal hygiene system comprises Balance intimate wash used daily, BioNourish vaginal moisturizing gel used daily, and BiopHresh homeopathic vaginal suppository containing probiotics, used once every 3 days. In addition, for all therapy requiring insertion in the clinic or at home, or for sex if desired, BioNude personal lubricant will be used. These four products are intended to allow the vaginal microbiome to self-correct by supporting the vaginal environment in terms of providing pH, osmolality, and lactic acid levels that match those in a healthy vagina.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine pelvic physical therapy
Description: Routine pelvic physical therapy may include external and internal manual techniques, exercises, diaphragmatic breathing exercises, and other modalities.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine pelvic physical therapy
Description: Routine pelvic physical therapy may include external and internal manual techniques, exercises, diaphragmatic breathing exercises, and other modalities.
Study: NCT05757557

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sham treatment
Description: Sham treatment: Oxygen-air mixture without NO after intubation, during CPB, and for six hours after surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 80-ppm NO
Description: NO will be supplemented at 80-ppm concentration to cardiac surgery patients perioperatively after trachea intubation, during CPB, and for six hours after surgery.
Study: NCT04912830

Intervention type: PROCEDURE
Intervention: Tension-free vaginal tape
Description: female incontinence surgery with polypropylene tape applied

Intervention type: PROCEDURE
Intervention: Tension-free vaginal tape
Description: female incontinence surgery with polypropylene tape applied
Study: NCT04886115

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No pedaling, usual activity
Description: Maintain usual physical activity and diet for a period of 6 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pedaling at 60rpm
Description: 3 sessions per week of training for 6 weeks
Study: NCT05916703

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: SOLUS examination
Description: The examination of each subject will include: i) B-mode US, ii), color Doppler US, iii) shear wave elastography, and iv) SOLUS multimodal imaging.~For each subject various ultrasound images (modalities i-iii) will be taken and these images will determine the location for the SOLUS measurements (iv).~All measurements (i-iv) will be taken at the lesion location, in the normal breast tissue around the lesion, and in the mirror location of the contralateral breast.~Optically derived data (blood volume, blood oxygen saturation, water, lipid and collagen concentrations, tissue scattering parameters) will be obtained. Every subject included in the study will be evaluated separately by 3 radiologists, with different level of experience in breast imaging.
Study: NCT05153928

Intervention type: DRUG
Intervention: Norethisterone acetate
Description: Norethisterone acetate for 5 months

Intervention type: DRUG
Intervention: Norethisterone acetate
Description: Norethisterone acetate for 5 months
Study: NCT05756712

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Phase 1 Wonderlab Product
Description: Chew two tablets of Wonderlab Product for phase 1 (day 1)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Phase 1 Placebo
Description: Washout 72 hours and chew two tablets of placebo for phase 2 (day 4).

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Phase 2 Placebo
Description: Chew two tablets of placebo for phase 1 (day 1)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Phase 2 Wonderlab Product
Description: Washout 72 hours and chew two tablets of Wonderlab Product for phase 2 (day 4).
Study: NCT05633628

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Periodic CGM group with data analysis report- Intervention group
Description: The patients are also instructed to continue to perform SMBG by finger prick if they experience symptoms of hypo- or hyperglycemia. During visit 0 (baseline) the patients is also instructed about how they can log in to the National Diabetes Register (NDR) to access their own NDR's recorded data and use the diabetes questionnaire.
Study: NCT06783556

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Ear Electroacupuncture of Battlefield Acupuncture (BFA) and paracetamol intravenous therapy
Description: Electroacupuncture therapy was performed 2 hours before PCNL surgery. Needle insertion was performed perpendicularly at the Battlefield Acupuncture (BFA) points of the ear, namely MA-IT1 Cingulate gyrus, MA-AT2 Thalamus, MA-H2 Omega2, MA-H1 Point Zero and MA-TF1 Shenmen bilaterally. Then the electrostimulator cable was connected to the ear acupuncture points MA-AT2 and MA-TF1 bilaterally on the same side and then fixed with plaster. Electroacupuncture uses continuous waves of 2 Hz frequency with an intensity that can be tolerated by the patient for 30 minutes.~Patients also received standard therapy with 1000 mg intravenous paracetamol with a maximum of 3 times administration per 24 hours and can be reduced according to the needs of the patient's pain complaints.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: The sham electroacupuncture and paracetamol intravenous therapy
Description: Sham electroacupuncture therapy was performed 2 hours before PCNL surgery. Needle only attached using plester (not inserted) at the Battlefield Acupuncture (BFA) points of the ear, namely MA-IT1 Cingulate gyrus, MA-AT2 Thalamus, MA-H2 Omega2, MA-H1 Point Zero and MA-TF1 Shenmen bilaterally. Then the electrostimulator cable was connected to the ear acupuncture points MA-AT2 and MA-TF1 bilaterally on the same side and then fixed with plaster. Electroacupuncture device is not turned on. The therapy is carried out for 30 minutes.~Patients also received standard therapy with 1000 mg intravenous paracetamol with a maximum of 3 times administration per 24 hours and can be reduced according to the needs of the patient's pain complaints.
Study: NCT06782607

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pneumonia Panel by FilmArray
Description: The Pneumonia Panel comprehensively identifies 33 potential pathogen targets from sputum-like (including endotracheal aspirate) and bronchoalveolar lavage (BAL)-like (including mini-BAL) samples. For 15 of the bacteria, the Pneumonia Panel provides semi-quantitative results, which may help determine whether an organism is a colonizer or a pathogen.
Study: NCT06784102

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Damon Clear Debonding Plier (the primary intervention being tested in this study).
Description: This clinical trial evaluates two types of orthodontic debonding pliers: the Damon Clear Debonding Plier and the traditional Bracket Remover Debonding Plier. The Damon Clear plier features a third wedging arm, which applies an additional lingual or palatal force in addition to the standard occluso-gingival force. The study is designed to assess and compare pain levels and debonding forces between the two pliers. A total of 40 patients, aged 17-25, were treated with both devices using a split-mouth design. The Damon Clear Plier is tested on one side of the mouth while the Bracket Remover Plier is used on the opposite side. Pain perception was measured immediately after the debonding procedure using the Numerical Rating Scale (NRS), and the forces applied during debonding were measured with a force-sensitive prototype. The study aims to identify the device that provides effective debonding with less pain.
Study: NCT06783543

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Comprehensive detumescence treatment with education video
Description: Comprehensive detumescence treatment, including skin care, manual lymphatic drainage, low elastic bandaging and functional exercise four steps

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Comprehensive detumescence treatment
Description: Three to five times a week, one hour each time
Study: NCT06787443

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Eligible subjects will receive Placebo to take daily for five weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Dietary Supplement with Proprietary Herbal Extract Blend and GABA
Description: Eligible subjects will receive active product to take daily for five weeks