TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06373211

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunoglobulins IV (CLAYRIG)
Description: Patients will be treated with cycles of :~- Intravenous (IV) immunoglobulins: 2 g/kg per cycle, over 3 to 5 days (D1 to D3 or D5).~Cycles will be administered every 4 weeks for a total of 3 first cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide IV
Description: Patients will be treated with cycles of :~- Cyclophosphamide IV: 1 g on the first day (D1). Cycles will be administered every 4 weeks for a total of 6 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone IV
Description: Patients will be treated with cycles of :~Methylprednisolone IV: 1 g/day for 3 days (D1 to D3). Cycles will be administered every 4 weeks for a total of 6 cycles
Study: NCT05650515

Intervention type: OTHER
Intervention: Co-creation
Description: The development of a technology-based exercise intervention based on ideas of older adults and experts in the field of geriatric rehabilitation/research/medicine
Study: NCT06181981

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI fingerprinting
Description: This method allows to get quantitative magnetic resonance imaging for the simultaneous measurement of multiple tissue properties in a single, time-efficient acquisition

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI fingerprinting
Description: This method allows to get quantitative magnetic resonance imaging for the simultaneous measurement of multiple tissue properties in a single, time-efficient acquisition

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI fingerprinting
Description: This method allows to get quantitative magnetic resonance imaging for the simultaneous measurement of multiple tissue properties in a single, time-efficient acquisition
Study: NCT05602285

Intervention type: DEVICE
Intervention: Dislodgement device
Description: Breakaway device that prevents IV dislodgement
Study: NCT05156411

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eccentric arm-cranking training
Description: Over the twenty training sessions, able-bodied participants will exercise on the KREHA device. An arm-crank has to be decelerated, which will be rotated by a prematurely defined revolution rate and training duration. During this intervention a certain power has to be applied. During the whole time of training a continous progression in power and training duration is applied
Study: NCT05763680

Intervention type: DIAGNOSTIC_TEST
Intervention: Molecular Culture
Description: PCR based technique that amplifies the interspace region in bacterial DNA, that is located between the genes coding for 16S and 23S ribosomal subunits. Primers are used for the majority of known pathogenic phyla, i.e. FAFV, Bacteroidetes, Firmicutes and Proteobacteria. The nucleotide length of the Interspace region is species specific for bacterial single species. Bacteria all have one or multiple alleles for this interspace region. The combination of the amount of alleles, as well as the nucleotide strand length, makes for a specific profile that is distinctive for the species. Available software is able to match this profile to a particular pathogen, enabling confirmation and identification of bacteria in samples within 5 hours in our experimental workflow.
Study: NCT05317702

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderately Painful Massage
Description: Participants will be seated in a chair with his or her shirt on. Participants will receive 60 seconds of manual pressure applied to the myofascial trigger point identified in the participant's upper back. The researcher's thumb or index finger will apply a deep manual pressure such that the participant rates the pain = 50/100 on a 101-point numeric pain rating scale with 0 indicating no pain and 100 indicating the most severe pain imaginable. The participant will be asked to rate his or her pain during the massage so the pressure may be adjusted to maintain the 50/100 related pain. Massage will be applied for 60 seconds, 4 times for a total contact time of 240 seconds. During each 30 second break in which manual pressure is released, Pressure Pain Threshold (PPT) to the foot will be examined. PPT will be assessed 2 times immediately after each of the 4 massage applications.
Study: NCT06048653

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A computer based cognitive rehabilitation program (Rehacom system)
Description: Rehacom cognitive rehabilitation software will be used to treat the cognitive dysfunction~* Patients will receive training for four weeks, two sessions per week.~* Each patient will assume a comfortable sitting position on a chair in front of the screen.~* A report will be generated at the end of the session. It will be used for follow up.~* Session duration will range from 45 to 60 min. including rest period.
Study: NCT05032638

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Upper extremity (UE) Training
Description: The 4-week UE training is completed in the participants home on their own and communication with study staff is virtual. Participants will receive daily communication through the Expiwell app to answer survey questions related to adherence, and safety/adverse events. Participants will also complete weekly check-ins with their research therapist over Zoom to answer questions about difficulties related to UE training activities, refinement of training goals, and to receive feedback on their training performance. Each weekly check-in will be approximately 45 minutes.
Study: NCT06242847

Intervention type: DIAGNOSTIC_TEST
Intervention: Oral glucose tolerance test (OGTT)
Description: Participants ingest 75 g of glucose in 10 fl oz aqueous solution (fruit flavored) after an overnight fast. Blood is drawn at baseline (t = 0 min) and at 120 min after ingestion. This test is non-experimental.

Intervention type: DIAGNOSTIC_TEST
Intervention: Oral glucose tolerance test (OGTT)
Description: Participants ingest 75 g of glucose in 10 fl oz aqueous solution (fruit flavored) after an overnight fast. Blood is drawn at baseline (t = 0 min) and at 120 min after ingestion. This test is non-experimental.
Study: NCT06048653

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A computer based cognitive rehabilitation program (Rehacom system)
Description: Rehacom cognitive rehabilitation software will be used to treat the cognitive dysfunction~* Patients will receive training for four weeks, two sessions per week.~* Each patient will assume a comfortable sitting position on a chair in front of the screen.~* A report will be generated at the end of the session. It will be used for follow up.~* Session duration will range from 45 to 60 min. including rest period.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vagus nerve stimulation
Description: stimulation will be applied on cymba conchae of left external ear. A stimulation of frequency of 20 Hz, pulse width of 200 - 300 Ms and intensity of 0.5 mA. The stimulation will be on for 30 s and off for 48 s.The stimulus duration will range from 20 to 40 min.
Study: NCT06242847

Intervention type: DIAGNOSTIC_TEST
Intervention: Oral glucose tolerance test (OGTT)
Description: Participants ingest 75 g of glucose in 10 fl oz aqueous solution (fruit flavored) after an overnight fast. Blood is drawn at baseline (t = 0 min) and at 120 min after ingestion. This test is non-experimental.

Intervention type: PROCEDURE
Intervention: Skin punch biopsy
Description: Punch biopsies are taken from lesional (psoriatic) and non-lesional skin after an overnight fast and at 120 min after ingestion of glucose during OGTT. This procedure is non-experimental.

Intervention type: PROCEDURE
Intervention: Skin punch biopsy
Description: Punch biopsies are taken from lesional (psoriatic) and non-lesional skin after an overnight fast and at 120 min after ingestion of glucose during OGTT. This procedure is non-experimental.

Intervention type: PROCEDURE
Intervention: Skin punch biopsy
Description: Punch biopsies are taken from lesional (psoriatic) and non-lesional skin after an overnight fast and at 120 min after ingestion of glucose during OGTT. This procedure is non-experimental.
Study: NCT05396794

Intervention type: BEHAVIORAL
Intervention: Standard weight loss education
Description: Participants will be randomized and given the standard weight loss education by the Gynecologic Oncology provider.

Intervention type: BEHAVIORAL
Intervention: Standard weight loss education + Educational Video
Description: Participants will be randomized and given the standard weight loss education by the Gynecologic Oncology provider followed by a 15-minute educational video detailing the benefits of weight loss.
Study: NCT04943172

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hancock-Jaffe bioprosthetic venous valve (VenoValve®)
Description: Surgical implantation of the VenoValve device
Study: NCT04740060

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augmented Feedback without Virtual Reality(VR
Description: For Walking Speed:One-minute fast walking with visual augmented feedback without VR interface (we ask participants to look at a screen where their walking speed and distance are tracked and increase their speed).~For Step Length: Maximum step length with visual augmented feedback without VR interface in which we ask participants to look at a screen where their step length is displayed and attempt to increase their step length up.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augmented Feedback with Non-Game based VR
Description: For Walking Speed:One-minute fast walking with basic VR interface (we ask participants to look at a screen where their avatar walker representative will be represented in a virtual walking environment and try to make the avatar walk faster).~For Step Length: Maximum step length with basic VR interface in which we ask participants to look at their avatar feet in a virtual stepping environment and step with the avatar foot as far as possible.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augmented Feedback with Game based VR
Description: For Walking Speed: One-minute fast walking with the VR Racing exergame (we ask participants to look at a screen where their avatar walker representative present in a virtual racing environment with other avatar racers and try to beat the avatar racers).~For Step Length: Maximum step length with the VR Stepping Exergame (we ask participants to look at their avatar legs and avatar animals in a virtual stepping environment and try to step over the avatar animals without touching the animal.
Study: NCT06338046

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Corthellus Shiitake(Mushroom) Extract
Description: topical treatment with Corthellus Shiitake(Mushroom) Extract

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: topical treatment with a placebo cosmetic formula
Study: NCT04995692

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telehealth Education for Asthma Connecting Hospital and Home
Description: TEACHH aims to provide educational support to families managing childhood asthma throughout the transition from hospital to home, and includes several core components: 1) Health literacy-informed inpatient teaching for child and caregiver including pictorial materials, hands-on demonstration, and use of teach-back/show-back techniques; 2) Facilitated identification of rescue and controller medications using color- and shape-coded medication labels and a pictorial asthma action plan; and 3) A pair of virtual follow-up visits after discharge to reinforce inpatient teaching and support families during the shift from acute exacerbation to preventive care management. Virtual visits will be completed using the Zoom platform on smartphones or other compatible devices, 2-4 days after discharge (first visit) and 3 weeks after discharge (second visit). All intervention activities will be completed within 1 month of discharge.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care (SC) Comparison Group
Description: Patients in the SC group will receive standard impatient management, including pre-recorded asthma education videos shown prior to discharge and the hospital action plan. PCP follow-up with be scheduled within a week of discharge. All SC measures will also be provided to subjects randomized to TEACHH.
Study: NCT05056766

Intervention type: BEHAVIORAL
Intervention: questionnaires: Epworth Sleepiness Scale; Pichot fatigue questionnaire.
Description: Each patient will undergo 3 to 7 polygraphy recordings according usual practice of titration At the same time, Self-questionnaires will be conducted by the patient in order to evaluate Oral appliance efficacy.~Optimal titration of oral appliance will be done according subjectives parameters. (sleepeness Reduction and fatigue Reduction).~Neither the investigator nor the patient will know the polygraphy results (apnea-hypopnea index)
Study: NCT05658263

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Standard Diet
Description: Participants receiving only standard of care (SOC) nutrition advice, which is SOC Dietary Instructions, as provided by routine surgical consults and one protein shake per day for 4 weeks prior to surgery (SOC).

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: BIG MACS Diet
Description: Participants will be instructed to consume the study diet, referred to as the 'BIG MACS Diet' and one protein shake per day for 4 weeks prior to surgery (SOC). Following surgery, participants will continue to follow the BIG MACS Diet for an additional four weeks, with solid food reintroduction after surgery as early as tolerated.
Study: NCT05135351

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Resistant Starch
Description: A prebiotic nutritional supplement available at commercial grocery and health food stores. Specifically, we will be using Bob's Red Mill® potato starch.
Study: NCT05853185

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pro Root MTA®
Description: Patients in this group will receive the pulpotomy with Pro Root MTA®.
Study: NCT05135351

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: A starch commonly used as a placebo in prebiotic trials that is digested in the stomach and rapidly absorbed
Study: NCT05187260

Intervention type: DRUG
Intervention: Nusinersen
Description: SPINRAZA® (nusinersen) prescribed as part of standard of care

Intervention type: DRUG
Intervention: Nusinersen
Description: SPINRAZA® (nusinersen) prescribed as part of standard of care

Intervention type: DRUG
Intervention: Nusinersen
Description: SPINRAZA® (nusinersen) prescribed as part of standard of care
Study: NCT06375980

Intervention type: OTHER
Intervention: Intraoperative Mechanical Ventilation Strategies
Description: The intervention involves the management of mechanical ventilation during major abdominal surgery. This includes the adjustment of ventilation parameters such as tidal volume, respiratory rate, peak pressure, positive end-expiratory pressure (PEEP), and inspiratory flow rate. The aim is to optimize ventilation strategies to reduce the risk of postoperative pulmonary complications

Intervention type: OTHER
Intervention: Intraoperative Mechanical Ventilation Strategies
Description: The intervention involves the management of mechanical ventilation during major abdominal surgery. This includes the adjustment of ventilation parameters such as tidal volume, respiratory rate, peak pressure, positive end-expiratory pressure (PEEP), and inspiratory flow rate. The aim is to optimize ventilation strategies to reduce the risk of postoperative pulmonary complications
Study: NCT05121909

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Colgate (R) Cavity Protection Toothpaste
Description: Participants will use Colgate (R) Cavity Protection Toothpaste for brushing teeth twice daily.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Colgate (R) Cavity Protection Toothpaste
Description: Participants will use Colgate (R) Cavity Protection Toothpaste for brushing teeth twice daily.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Colgate (R) Cavity Protection Toothpaste
Description: Participants will use Colgate (R) Cavity Protection Toothpaste for brushing teeth twice daily.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Colgate (R) Cavity Protection Toothpaste
Description: Participants will use Colgate (R) Cavity Protection Toothpaste for brushing teeth twice daily.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Colgate (R) Cavity Protection Toothpaste
Description: Participants will use Colgate (R) Cavity Protection Toothpaste for brushing teeth twice daily.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Colgate (R) Cello Toothbrush
Description: Participants will use Colgate (R) Cello Toothbrush for brushing teeth twice daily.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Colgate (R) Cello Toothbrush
Description: Participants will use Colgate (R) Cello Toothbrush for brushing teeth twice daily.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Colgate (R) Cello Toothbrush
Description: Participants will use Colgate (R) Cello Toothbrush for brushing teeth twice daily.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Colgate (R) Cello Toothbrush
Description: Participants will use Colgate (R) Cello Toothbrush for brushing teeth twice daily.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Colgate (R) Cello Toothbrush
Description: Participants will use Colgate (R) Cello Toothbrush for brushing teeth twice daily.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prototype 1 Mouthwash
Description: Participants will use 20 mL of Prototype 1 Mouthwash for 30 seconds after brushing twice daily.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prototype 2 Mouthwash
Description: Participants will use 20 mL of Prototype 2 Mouthwash for 30 seconds after brushing twice daily.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prototype 3 Mouthwash
Description: Participants will use 20 mL of Prototype 3 Mouthwash for 30 seconds after brushing twice daily.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Listerine (R) Cool Mint (R) Antiseptic Mouthwash
Description: Participants will use 20 mL of Listerine (R) Cool Mint (R) Antiseptic Mouthwash for 30 seconds after brushing twice daily.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 5% Hydroalcohol Mouthwash
Description: Participants will use 20 mL of 5% Hydroalcohol Mouthwash for 30 seconds after brushing twice daily.
Study: NCT05757089

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ALCOFILTRUM
Description: ALCOFILTRUM helps alleviate alcohol hangover symptoms after a single intake for 30 minutes before alcohol consumption.
Study: NCT06259864

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EXOPULSE Mollii Suit method
Description: EXOPULSE Mollii Suit method, one of the newest rehabilitation technology products, is a non-invasive neuromodulation approach with a garment that covers the whole body and electrodes placed inside. Designed to improve motor function by reducing spasticity and pain, the method is based on the principle of reciprocal inhibition, which occurs by stimulating the antagonist of a spastic muscle at low frequencies and intensities.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: EXOPULSE Mollii Suit method
Description: EXOPULSE Mollii Suit method, one of the newest rehabilitation technology products, is a non-invasive neuromodulation approach with a garment that covers the whole body and electrodes placed inside. Designed to improve motor function by reducing spasticity and pain, the method is based on the principle of reciprocal inhibition, which occurs by stimulating the antagonist of a spastic muscle at low frequencies and intensities.
Study: NCT05260892

Intervention type: DEVICE
Intervention: Narrow GM implants
Description: Rehabilitation of superior lateral incisors or inferior central and lateral incisors with narrow implants supporting single unit or partial prostheses
Study: NCT05557669

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic cholecystectomy
Description: Laparoscopic cholecystectomy is a procedure of removal of the gallbladder and a gold standard in treatment of gallstone disease.
Study: NCT05528770

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FCL+BPS
Description: The automated insulin delivery system includes the Bolus Priming System, a software automatically analyzing past continuous glucose monitoring values to trigger priming insulin bolus delivery isn the suspected presence of meal like glycemic disturbances

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FCL+BPS
Description: The automated insulin delivery system includes the Bolus Priming System, a software automatically analyzing past continuous glucose monitoring values to trigger priming insulin bolus delivery isn the suspected presence of meal like glycemic disturbances

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FCL
Description: The automated insulin delivery system does not include the Bolus Priming System, and therefore does not automatically command priming boluses.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FCL
Description: The automated insulin delivery system does not include the Bolus Priming System, and therefore does not automatically command priming boluses.
Study: NCT04800393

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane
Description: induction of anesthesia with propofol, maintenance of anesthesia with sevoflurane during breast cancer surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: propofol-based total intravenous anesthesia during breast cancer surgery
Study: NCT05818826

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: normal saline solution
Description: Prepare 100 ml of normal saline solution, packed out in the same format, dose, and administration of the drug were exactly the same as in the conventional cessation group.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Hydrocortisone and normal saline solution
Description: Prepare hydrocortisone with normal saline solution 100 ml starts dose at least 200 mg/day according to doctor's order after patient meets the criteria of refractory septic shock then continues conventional cessation of hydrocortisone according to doctor's order after required dose of vasopressor less than 0.1 mcg/kg/min.
Study: NCT04404023

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UB-221
Description: UB-221 (75 mg/ml)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UB-221
Description: UB-221 (75 mg/ml)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UB-221
Description: UB-221 (75 mg/ml)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UB-221
Description: UB-221 (75 mg/ml)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UB-221
Description: UB-221 (75 mg/ml)