TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06610578

Intervention type: DIAGNOSTIC_TEST
Intervention: fundus imaging
Description: Fundus photography, OCT or OCTA
Study: NCT06665334

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Huaier granule
Description: Oral administration, 10g per dose (1 bag), 3 times a day, recommended for at least 6 months.
Study: NCT06665490

Intervention type: OTHER
Intervention: CLn Body Wash
Description: All enrolled patients will self-administer at home the commercially available study product (CLn Body Wash) containing 0.006% NaOCl body wash in a sealed, child-safe pump dispenser to use daily for 8 weeks by wetting the body thoroughly with showering, lathering the study product on the body with special attention to affected areas, leaving on the skin for 2 minutes, and rinsing off with warm water.
Study: NCT06668662

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Endoactivator
Description: Endoactivator is an irrigation technique which will help to reduce post-operative pain in patients following endodontic treatment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional irrigation
Description: Conventional irrigation is an irrigation technique which will help to reduce post-operative pain in patients following endodontic treatment.
Study: NCT06668519

Intervention type: OTHER
Intervention: Magnetoencephalography
Description: Magnetoencephalography

Intervention type: OTHER
Intervention: Magnetoencephalography
Description: Magnetoencephalography
Study: NCT06668168

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ketone Monoester (KE)
Description: 25g ketone ester 3x/day. The ketone ester will be a beta-hydroxybutyrate monoester \[(R)-3-hydroxybutyl (R)-3-hydroxybutyrate\].
Study: NCT05648825

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transapical beating-heart septal myectomy
Description: We have invented a beating-heart myectomy device. Using this device, myectomy could be performed in the beating heart via a mini-thoractomy approach. The whole process of resection is monitored, navigated, and evaluated by real-time transesophageal and transthoracic echocardiography. We are now conducting the study to explore the feasibility, the safety, and the efficacy of transapical beating-heart myectomy for the treatment of apical hypertrophic cardiomyopathy.
Study: NCT04766632

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Brain PET-CT of 18F-DOPA
Description: PET-CT is a nuclear medicine exam with radiopharmaceutical injection of 18F-DOPA for the patient
Study: NCT05614414

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: tracheal intubation by Videolaryngoscope
Description: The investigators performed laryngoscopy using a McGrath video-laryngoscope with a number 4 blade.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: tracheal intubation by direct laryngoscope
Description: The investigators performed laryngoscopy using either a Macintosh laryngoscope using a number 4 blade.
Study: NCT05159323

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Diffusion Spectrum Imaging
Description: A novel diffusion-based magnetic resonance imaging method
Study: NCT05239988

Intervention type: OTHER
Intervention: no experimental intervention
Description: There will not be any experimental intervention. The study will be conducted according with normal clinical practice
Study: NCT05412888

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: CoQ10 supplementation
Description: Young men training endurance running will be supplemented with CoQ10

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ischemic preconditioning training
Description: Young men training endurance running will undergo IPC training

Intervention type: DIETARY_SUPPLEMENT
Group type: SHAM_COMPARATOR
Intervention: IPC training combined with CoQ10 supplementation
Description: Young men training endurance running will undergo IPC training combined with CoQ10 supplementation

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Sham IPC combined with placebo
Description: Young men training endurance running will undergo sham IPC training combined with placebo supplementation
Study: NCT04732052

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: non-invasive brain stimulator

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: non-invasive brain stimulator
Study: NCT05856370

Intervention type: DEVICE
Group type: OTHER
Intervention: Follow-up schedule: pre-operative baseline up to 24-months post-procedure
Description: Follow-up assessments will be required (therefore interventional) from pre-operative baseline to 24 months post index surgery
Study: NCT02878174

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: internal jugular vein catheterization
Description: internal jugular vein catheterization using ultrasound (US) or US-based prelocation techniques

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: internal jugular vein catheterization
Description: internal jugular vein catheterization using ultrasound (US) or US-based prelocation techniques
Study: NCT06052449

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social determinants of health screening assessment and referral process
Description: Unite Us is an electronic SDoH screening and referral tool assessing: (1) financial resource strain; (2) housing stability; (3) transportation needs; and (4) food insecurity. Upon completion, the Unite Us platform identifies a list of geographically-tailored resources to connect the individual in need. A staff member will administer the SDoH screening and referral tool, review the results with the participant, and use the geographically-tailored resources to make SDoH-related referrals.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Current practice - Community-based lunch cancer screening (LungTalk)
Description: The current practice during community events is to offer LungTalk. LungTalk is a novel theoretically grounded health educational tool that will be delivered via iPad and is an interactive computer-based program that includes audio, video and animation segments with scripts presented from a master content library in consideration of different ways people like to learn. Informed by our prior research, LungTalk tailors its content based on smoking status and perceived barriers. In prior work, LungTalk more than doubled LCS knowledge and health beliefs (p \< 0.01), and was associated with a significant increase in deciding to screen for lung cancer compared to control group; OR 1.99; 95% Confidence Interval (CI), 1.03, 3.85, p = 0.03.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Current practice - Community-based lunch cancer screening (LungTalk)
Description: The current practice during community events is to offer LungTalk. LungTalk is a novel theoretically grounded health educational tool that will be delivered via iPad and is an interactive computer-based program that includes audio, video and animation segments with scripts presented from a master content library in consideration of different ways people like to learn. Informed by our prior research, LungTalk tailors its content based on smoking status and perceived barriers. In prior work, LungTalk more than doubled LCS knowledge and health beliefs (p \< 0.01), and was associated with a significant increase in deciding to screen for lung cancer compared to control group; OR 1.99; 95% Confidence Interval (CI), 1.03, 3.85, p = 0.03.
Study: NCT06446505

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep Brain Stimulation Decision Aid
Description: An online decision support tool that provides education about deep brain stimulation and the alternatives, and includes value clarification exercise.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep Brain Stimulation Decision Aid
Description: An online decision support tool that provides education about deep brain stimulation and the alternatives, and includes value clarification exercise.
Study: NCT04757415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traction straight leg raise technique for hamstring
Description: traction straight leg raise technique is used along with gluteal exercises

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gluteal activation exercises,Hotpack
Description: only gluteal activation exercises were performed without traction straight leg raise technique
Study: NCT05443243

Intervention type: PROCEDURE
Intervention: Total Hip Arthroplasty
Description: Patient were operated, a Total hip arthroplasty was performed

Intervention type: PROCEDURE
Intervention: Total Hip Arthroplasty
Description: Patient were operated, a Total hip arthroplasty was performed
Study: NCT05942612

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-2001
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous injection, single dose
Study: NCT04642456

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Balance Assessment Scale
Description: The newly developed balance, based on the Balance Evaluation Systems Test (BESTest) and Trunk Control Measurement Scale (TCMS), will be administered by two raters (normative and clinical database + interrater reliability)
Study: NCT06668168

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ketogenic diet
Description: Ketogenic diet (\<50 g carbohydrate per day)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo taste-matched to ketone monoester

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo taste-matched to ketone monoester
Study: NCT06668129

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Back care intervention program
Description: The back care intervention consists of:~1. Nine oral presentations. Include Programa Suma't programme developed by the Provincial Council of Majorca.~2. Multisubject Teaching Unit.~3. Information campaign widespread by the school (i.e. posters, triptychs, school website, social networks, etc.)~4. The Back Care Day at school.
Study: NCT06539624

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: EXG110 injection
Description: EXG110 is a recombinant adeno-associated virus (rAAV) that not only significantly increases plasma AGA activity, but is also highly expressed in target organs such as the heart and kidneys.EXG110 will be administered in a single dose by intravenous infusion.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: EXG110 injection
Description: EXG110 is a recombinant adeno-associated virus (rAAV) that not only significantly increases plasma AGA activity, but is also highly expressed in target organs such as the heart and kidneys.EXG110 will be administered in a single dose by intravenous infusion.
Study: NCT04642456

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Balance Assessment Scale
Description: The newly developed balance, based on the Balance Evaluation Systems Test (BESTest) and Trunk Control Measurement Scale (TCMS), will be administered by two raters (normative and clinical database + interrater reliability)

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Trunk strength measurement with EMG
Description: A trunk strength protocol in sitting position, using a hand-held dynamometer is developed. During the trunk strength measurements muscle activity of certain muscles of the trunk will be measured using surface electromyography (EMG)

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Trunk strength measurement with EMG
Description: A trunk strength protocol in sitting position, using a hand-held dynamometer is developed. During the trunk strength measurements muscle activity of certain muscles of the trunk will be measured using surface electromyography (EMG)

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: MRI spine/pelvis
Description: We will be capturing 3D Magnetic Resonance (MR) images of the subject lying supine with extended knees, using a T1 weighted spine-echo (SE) sequence with interslice distance 3 mm in the area of the hip) extended with full spine MRI images (sagittal full spine T1- and T2- weighted images as part of the standard sagittal view of full spine to check for significant stenosis or spinal cord pathology) and additional T1-weighted axial slices at level L4, T12 and T8 with interslice distance 4 mm.The field of view covers the full spine, pelvis and hip smaller trochanter.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: MRI spine/pelvis
Description: We will be capturing 3D Magnetic Resonance (MR) images of the subject lying supine with extended knees, using a T1 weighted spine-echo (SE) sequence with interslice distance 3 mm in the area of the hip) extended with full spine MRI images (sagittal full spine T1- and T2- weighted images as part of the standard sagittal view of full spine to check for significant stenosis or spinal cord pathology) and additional T1-weighted axial slices at level L4, T12 and T8 with interslice distance 4 mm.The field of view covers the full spine, pelvis and hip smaller trochanter.
Study: NCT05423379

Intervention type: DEVICE
Intervention: XIENCE Skypoint Large Vessel Everolimus Eluting Coronary Stent System (EECSS)
Description: XIENCE Skypoint Large Vessel EECSS is composed of a L-605 CoCr stent and coated with poly (n-butyl methacrylate) (PBMA) primer and a drug coating formulation of polymer of vinylidene fluoride and hexafluoropropylene (PVDF-HFP)/everolimus pre-mounted on a balloon catheter delivery system.
Study: NCT05871177

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pre-filled syringe of HiLow Hyaluronic Acid Sodium Salt
Description: The medical device consists of a pre-filled syringe containing 3.2% Hyaluronic Acid Sodium Salt with high and low molecular weight \[32 mg (HHA) + 32 mg (LHA) / 2 ml\]
Study: NCT06539624

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: EXG110 injection
Description: EXG110 is a recombinant adeno-associated virus (rAAV) that not only significantly increases plasma AGA activity, but is also highly expressed in target organs such as the heart and kidneys.EXG110 will be administered in a single dose by intravenous infusion.
Study: NCT06538831

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet N+P+
Description: Rich in SFAs, free sugar and sodium; High in UPFs
Study: NCT05598203

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Operative group of nutrition education
Description: The intervention will be carried out with operational nutritional education groups. Four meetings will be held, each meeting lasting one hour, weekly or fortnightly (according to the availability of the patient). The following foods proposed foods: Meeting 1 = education on classification labels and proposed foods proposed foods (education on classification labels and substitution of Brazilian foods), in this guide meeting the proposal is processed or ultra-processed by an in natura food or minimally processed; Meeting 2 = assembly of the healthy dish (food portions, food index and glycemic load, food clothes), the proposal in this meeting is the assembly of the complete dish in the meals eaten throughout the day; and Encounter 3 = hunger and satiety (aiming to increase the perception of hunger and satiety signals), encounter as a task to be accomplished; Encounter 4 = strengthening change, barriers and difficulties in maintaining habits based on the transtheoretical model of change.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Operative group of nutrition education
Description: The intervention will be carried out with operational nutritional education groups. Four meetings will be held, each meeting lasting one hour, weekly or fortnightly (according to the availability of the patient). The following foods proposed foods: Meeting 1 = education on classification labels and proposed foods proposed foods (education on classification labels and substitution of Brazilian foods), in this guide meeting the proposal is processed or ultra-processed by an in natura food or minimally processed; Meeting 2 = assembly of the healthy dish (food portions, food index and glycemic load, food clothes), the proposal in this meeting is the assembly of the complete dish in the meals eaten throughout the day; and Encounter 3 = hunger and satiety (aiming to increase the perception of hunger and satiety signals), encounter as a task to be accomplished; Encounter 4 = strengthening change, barriers and difficulties in maintaining habits based on the transtheoretical model of change.
Study: NCT05291585

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: the dedicated venous sinus thrombectomy stent
Description: the dedicated venous sinus thrombectomy stent in conjunction with aspiration for CVST patients within 28 days of symptom onset.
Study: NCT06664138

Intervention type: DRUG
Group type: OTHER
Intervention: Remimazolam
Description: Remimazolam is a recently approved medication used for the induction of general anesthesia and maintenance of sedation. There have been no prior studies using remimazolam for the induction of anesthesia in ECT, and this research aims to investigate the feasibility of using remimazolam as an induction agent for ECT.

Intervention type: DRUG
Group type: OTHER
Intervention: Remimazolam
Description: Remimazolam is a recently approved medication used for the induction of general anesthesia and maintenance of sedation. There have been no prior studies using remimazolam for the induction of anesthesia in ECT, and this research aims to investigate the feasibility of using remimazolam as an induction agent for ECT.

Intervention type: DRUG
Group type: OTHER
Intervention: Etomidate
Description: Etomidate is widely used in ECT due to its rapid onset, stable hemodynamic profile, and quick recovery. In this study, remimazolam will be used as the experimental group, while etomidate will serve as the control group.

Intervention type: DRUG
Group type: OTHER
Intervention: Etomidate
Description: Etomidate is widely used in ECT due to its rapid onset, stable hemodynamic profile, and quick recovery. In this study, remimazolam will be used as the experimental group, while etomidate will serve as the control group.
Study: NCT06680687

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational Program (video, information booklet, Survivorship Card)
Description: Caregivers will be invited to attend an educational group session. Each session will be organized weekly to monthly. A maximum of ten caregivers can be present at a session.~First a video will be displayed in which healthcare providers explain medical aspects of survivorship. Caregivers of survivors and young adult survivors discuss experiences after completing cancer treatment in the video.~Secondly, the present healthcare provider will hand over an information booklet 'Life after childhood cancer' to the caregivers. The booklet covers similar topics as presented in the video.~Lastly, a Survivorship Card will be shared with the caregivers. The card contains a record of the patient's cancer and treatment history and the expected follow-up appointment schedule. The survivor and family take one card home and a duplicate copy of the card remains in the medical file.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Follow-Up Program (form and healthcare provider training)
Description: Healthcare providers will attend a training session of approximately 90 minutes, in which investigators will discuss the same topics as covered in the educational group session supported by PowerPoint slides.~A Follow-Up Form will be introduced to be used by healthcare providers in the outpatient follow-up clinic. The form will include questions referring to symptoms specific for certain late effects. Specific questions will be included per subcategory: hematological malignancies, solid tumors or central nervous system (CNS) tumors.
Study: NCT06412757

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Silexan
Description: Participants in the Silexan arm will take two over-encapsulated capsules, each containing 80 mg Silexan, daily orally in the morning in addition to their usual medications. No modifications of allocated interventions will be made for any trial participants; if appropriate (i.e following the emergence of adverse events) participants will be withdrawn from the intervention.
Study: NCT03948984

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Therapeutic Music Session
Description: The 20 minute therapeutic music session will consist of classical music performed by a pianist with or without flute accompaniment with an individual patient's ICU room.
Study: NCT06412757

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants in the placebo arm will take two capsules containing an inert placebo daily orally in the morning in addition to their usual medications. The placebo capsules will contain a sub-therapeutic amount of lavender oil to mimic the odor of the experimental drug (Silexan).
Study: NCT04978428

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol
Description: Epidiolex oral solution (2.5 mg/kg and 5 mg/kg)