TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05190458

Intervention type: OTHER
Group type: OTHER
Intervention: High Velocity Nasal Insufflation
Description: High velocity nasal insufflation (HVNI), a form of HFNC that utilizes a small bore nasal cannula to generate higher velocities of gas delivery than HFNC which uses large bore cannula, has the ability to accomplish complete purge of extra thoracic dead space at flow rates of 35 litres/min and may be able to provide ventilatory support in patients with respiratory failure in addition to oxygenation support in patients with overlap syndrome.

Intervention type: OTHER
Group type: OTHER
Intervention: Non-invasive mechanical ventilation
Description: Noninvasive ventilation (NIV) refers to the administration of ventilatory support without using an invasive artificial airway (endotracheal tube or tracheostomy tube).
Study: NCT05241223

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Behavior change intervention
Description: This is an online intervention based on the transtheoretical model, along with self-determination theory strategies. This intervention will take place weekly summing up 12 online individual and/or group sessions of approximately 20 minutes. The sessions will be made through a platform and/or application that makes video calls privately. Each session will address a topic. In addition, in all sessions, the patients gain during the previous week will be recognized, as well as new goals will be set for the next week. The goals will always be individualized, realistic and achievable, based on the identification of each person's capacity and motivation. A Fitbit Zip will be used to propose objective goals aimed at increasing physical activity and reduce sedentary behavior. Additionally, a complex practice environment will be created around this device, such as the visualization of the number of steps evolution and competitions/games with other participants, among others.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Educational program
Description: The educational program will be delivered similarly to both groups through videos and booklets, which will be sent in all weekdays during de first week after the initial assessment. Later, one educational material will be sent every two weeks until de 11th week. In the first day, patients will receive a quick welcome video call, in which information will be provided on how this program will work. In the subsequent days, the material will be sent daily and the participants will be able to ask questions, if they want to. The program will cover information regarding the respiratory system, pathophysiology of asthma, asthma treatment, prevention strategies and medication instructions. It will also be briefly addressed the subjects: understanding physical activity and sedentarism, as well as the importance and benefits of being physically active and less sedentary.
Study: NCT04962568

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DTEE
Description: endexpiratory diaphragm thickness in mm
Study: NCT06264271

Intervention type: BEHAVIORAL
Intervention: structured nutrition intervention
Description: Structured nutrition education on carbohydrate counting and flexible insulin dosing by qualified nutritionist.
Study: NCT04962568

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DTEE
Description: endexpiratory diaphragm thickness in mm

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DTEI
Description: endinspiratory diaphragm thickness in mm

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DTEI
Description: endinspiratory diaphragm thickness in mm

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DEx
Description: diaphragm excursion during rest and diaphragmatic excursion during maximal inspiration in mm

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DEx
Description: diaphragm excursion during rest and diaphragmatic excursion during maximal inspiration in mm
Study: NCT03372148

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: pHRMi
Description: Pharyngeal High Resolution Manometry and Impedance swallowing function evaluation
Study: NCT05253482

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: wet cupping therapy
Description: Vacuum cups will used on different acupuncture points to perform WCT: The one on the posterior median line, in the depression below the processus spinosus of the 7th cervical vertebra was DU 14 (Dazhui) point; the ones on the back, 3.0 cm lateral to the lower border of the spinous process of the 3rd thoracic vertebra interscapulum region were UB 42 (Pohu) bilateral points; and the ones on the back, 3.0 cm lateral to the lower border of the spinous process of the 7th thoracic vertebra were UB 46 (Geguan) bilateral points and additionally the patient's trigger points which we detect during the examination. There will be 5-7 points in total. The technique used will be triple S (Sucking, Scarification, Sucking) in all sessions.
Study: NCT06329154

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extracorporeal shock wave therapy
Description: The experimental group received extracorporeal shock wave therapy combined with conventional rehabilitation therapy. The control group was only given conventional rehabilitation therapy. According to the patient's tolerance and the specific condition, extracorporeal shock wave therapy was performed twice a week, 2000-3000 times each time, energy parameters of 2.5-3.5Bar, 8-15Hz, treatment interval \> 1 day, consecutive 4 weeks. Conventional rehabilitation therapy included medium frequency electricity, ultrasound, ultrashort wave, laser and wax therapy. Routine rehabilitation was given once a day, 5 times a week for 4 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional rehabilitation therapy
Description: Conventional rehabilitation therapy included medium frequency electricity, ultrasound, ultrashort wave, laser, and wax therapy (same as the control group). Routine rehabilitation was given once a day, 5 times a week for 4 weeks.
Study: NCT06118294

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: probiotics
Description: \>30 billion CFU/capsule

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05943444

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Parks technique
Description: compare different operational styles of low rectal cancer
Study: NCT06016127

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iovera system
Description: The iovera° system consists of a reusable, portable Handpiece, along with single patient use sterile Smart Tips (i.e., cryoprobes) and disposable nitrous oxide (N2O) cartridges. The iovera° system produces the desired effect through initiation of a cooling cycle. Each cooling cycle is initiated by fully inserting the Smart Tip into the selected procedure site and activating the cryogen flow. The Smart Tip needles are made of stainless steel and have a closed tip, fully enclosing the cryogen. The 190 Smart Tip will be used in this study.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency ablation
Description: The RFA system consists of a Cosman, G4 Generator. The needles used are 20-gauge, 10cm long with a 10mm active tip manufactured by Cosman. A grounding pad, also manufactured by Cosman, is placed on the upper thigh for each procedure and connected to the G4 Generator.
Study: NCT05492721

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 2-Octylcyanoacrylate
Description: Incisions on left will have one glue and on right will have the other glue
Study: NCT05943444

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bacon technique
Description: Bacon technique
Study: NCT05120193

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mapping and Ablation
Description: Minimally invasive catheter mapping and ablation procedure

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mapping and Ablation
Description: Minimally invasive catheter mapping and ablation procedure
Study: NCT04700514

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine (1 mcg/kg loading for 10 min, then 1 mcg/kg/min continuous infusion) is used with sevoflurane in every time of general anesthesia
Study: NCT06444620

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DTG/3TC
Description: This is a fixed-dose combined DTG/3TC pill each containing 50mg of dolutegravir and 300mg of lamivudine
Study: NCT05492721

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: N-butyl-2-cyanoacrylate
Description: Incisions on left will have one glue and on right will have the other glue
Study: NCT06450834

Intervention type: DEVICE
Intervention: Ostene
Description: Soluble Bone Hemostasis Implant Material
Study: NCT05820256

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Milk Protein Isolate (MPI)
Description: Study participants will consume two smoothies per day containing a milk protein isolate (MPI) for 31 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Soy Protein Isolate (SPI)
Description: Study participants will consume two smoothies per day containing a soy protein isolate (SPI) for 31 days.
Study: NCT05656404

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TorEx Lung Perfusion System
Description: When donor lungs with clinical indication for EVLP are allocated to consented recipients, the lungs will be assessed using the second generation TorEx Lung Perfusion System rather than the first generation Toronto EVLP technique (standard of care).
Study: NCT06090487

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: myocardial function after surgery
Description: This group includes (15) patients who will have 200 mg twice daily oral (5) sacubitril-valsartan 1 month before the operation. transthoracic echo will be done before and after surgery, also total dose if inoptropic drugs will be noted
Study: NCT04922801

Intervention type: DIAGNOSTIC_TEST
Intervention: Nuclear Medicine whole-body
Description: Gamma-Camera Whole-body scan at 24-48 hour post-Molecular Radiotherapy (MRT).

Intervention type: DIAGNOSTIC_TEST
Intervention: Nuclear Medicine whole-body
Description: Gamma-Camera Whole-body scan at 24-48 hour post-Molecular Radiotherapy (MRT).

Intervention type: DIAGNOSTIC_TEST
Intervention: Nuclear Medicine whole-body
Description: Gamma-Camera Whole-body scan at 24-48 hour post-Molecular Radiotherapy (MRT).

Intervention type: DIAGNOSTIC_TEST
Intervention: SPECT/CT imaging.
Description: SPECT/CT scan at 24-48 hr post MRT

Intervention type: DIAGNOSTIC_TEST
Intervention: SPECT/CT imaging.
Description: SPECT/CT scan at 24-48 hr post MRT

Intervention type: DIAGNOSTIC_TEST
Intervention: PET/CT imaging.
Description: 3-6 months Pre and post-therapy PET/CT imaging

Intervention type: DIAGNOSTIC_TEST
Intervention: PET/CT imaging.
Description: 3-6 months Pre and post-therapy PET/CT imaging

Intervention type: DIAGNOSTIC_TEST
Intervention: PET/CT imaging.
Description: 3-6 months Pre and post-therapy PET/CT imaging

Intervention type: DEVICE
Intervention: Patient-led radiation monitor (SELFIE)
Description: Following MRT administration, a standard whole body dosimetry measurement will be taken by medical physicist at 1 and 2 meters distance. The patient will begin to take SELFIE readings at the same time under supervision so that their records can be compared with the physicists' results.~After 28 days, patients will be asked to return the diary sheet and SELFIE monitor by post to GSTTFT in a pre-paid, pre-addressed envelope.~On completion of the 28 day exercise, patients will be asked to complete and return a feedback questionnaire.
Study: NCT06068088

Intervention type: BEHAVIORAL
Intervention: Self-administered survey at hospital
Description: Self-administered survey on the food practices of the patient Completion before the beginning of chemoradiotherapy

Intervention type: BEHAVIORAL
Intervention: Self-administered survey at hospital
Description: Self-administered survey on the food practices of the patient Completion before the beginning of chemoradiotherapy

Intervention type: BIOLOGICAL
Intervention: Blood sample for nutritional assessment
Description: 15 ml of blood sampled during nutritional examination before the beginning and during the month following the end of chemoradiotherapy

Intervention type: OTHER
Intervention: Consultation with nutritionist doctor and dietician
Description: Before the beginning and during the month following the end of chemoradiotherapy Consultation of approximatively one hour
Study: NCT05694169

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Renal Autologous Cell Therapy (REACT)
Description: Autologous selected renal cells (SRC)
Study: NCT05475535

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy
Description: Cognitive Behavioural Therapy
Study: NCT04922801

Intervention type: DEVICE
Intervention: Patient-led radiation monitor (SELFIE)
Description: Following MRT administration, a standard whole body dosimetry measurement will be taken by medical physicist at 1 and 2 meters distance. The patient will begin to take SELFIE readings at the same time under supervision so that their records can be compared with the physicists' results.~After 28 days, patients will be asked to return the diary sheet and SELFIE monitor by post to GSTTFT in a pre-paid, pre-addressed envelope.~On completion of the 28 day exercise, patients will be asked to complete and return a feedback questionnaire.

Intervention type: DEVICE
Intervention: Patient-led radiation monitor (SELFIE)
Description: Following MRT administration, a standard whole body dosimetry measurement will be taken by medical physicist at 1 and 2 meters distance. The patient will begin to take SELFIE readings at the same time under supervision so that their records can be compared with the physicists' results.~After 28 days, patients will be asked to return the diary sheet and SELFIE monitor by post to GSTTFT in a pre-paid, pre-addressed envelope.~On completion of the 28 day exercise, patients will be asked to complete and return a feedback questionnaire.

Intervention type: DIAGNOSTIC_TEST
Intervention: LAB TEST
Description: Biochemistry, haematology and tumour markers blood tests pre, post and during MRT.

Intervention type: DIAGNOSTIC_TEST
Intervention: LAB TEST
Description: Biochemistry, haematology and tumour markers blood tests pre, post and during MRT.

Intervention type: DIAGNOSTIC_TEST
Intervention: LAB TEST
Description: Biochemistry, haematology and tumour markers blood tests pre, post and during MRT.
Study: NCT05475535

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy
Description: Cognitive Behavioural Therapy

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Compassion
Description: Self-Compassion focused exercises

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Compassion
Description: Self-Compassion focused exercises

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Control
Description: Engagement in a mobile application (Cooperation skills)
Study: NCT06415305

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Winlevi (clascoterone) 1% cream
Description: Dosed twice daily (BID)
Study: NCT06621511

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OurSleepKit
Description: OurSleepKit is developed as an app including a patient version and a partner version, to be downloaded on the patient's or partner's mobile devices at home. The goal of OurSleepKit is to coach mutual engagement and model positive partner involvement in CPAP treatment, thus motivating greater CPAP adherence. Using OurSleepKit, both the patient and partner will complete periodic assessments tracking various aspects of their sleep and CPAP use. The assessment data are then processed by OurSleepKit to provide customized and dynamically updated support content consisting of brief story-telling videos featuring real-life couples' experiences emphasizing positive dyadic coping and problem-solving strategies. OurSleepKit delivers timely tailored prompts through push notifications on the users' mobile devices' screens, linked to relevant support content, to facilitate positive conversation in the dyad and offer in-the-moment support for CPAP use.
Study: NCT06700486

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SOCKET SHIELD
Description: in implant dentistry

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Immediate implant and sticky bone
Description: in implant dentistry
Study: NCT03759093

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bortezomib
Description: Standard dosing based on product insert and subjected to dose adjustments as determined by clinical care team

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide
Description: Standard dosing based on product insert and subjected to dose adjustments as determined by clinical care team

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Standard dosing based on product insert and subjected to dose adjustments as determined by clinical care team

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CURATE.AI-Guided dosage modulation
Description: CURATE.AI-guided modulation of Velcade and Cyclophosphamide dosages for VCD regimen, Velcade and Thalidomide dosages for VTD regimen, and Velcade and Lenalidomide dosages for VRD regimen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Thalidomide
Description: Standard dosing based on product insert and subjected to dose adjustments as determined by clinical care team

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Dose in a range of 0.7,1.0,1.3 mg/m2 subcutaneous (SC) injection on Day 1, 8, 15 ,22 for cycles 1 to 4 , as determined and guided by CURATE.AI and approved by the clinical care team

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Dosing in a range of 100, 300, 500 mg PO on Day 1, 8, 15, 22 for cycles 1 to 4 as determined and guided by CURATE.AI and approved by the clinical care team.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thalidomide
Description: Dose in a range of 50-200mg PO on day 1-28 for cycles 1 to 4 as determined and guided by CURATE.AI and approved by the clinical care team.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: 40 mg PO on Day 1 ,8 , 15, 22 for cycles 1 to 4, as determined and guided by the clinical care team according to standard of care

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lenalidomide
Description: Standard dosing based on product insert and subjected to dose adjustments as determined by clinical care team

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Dose in a range of 5-25mg PO on day 1-21 for cycles 1 to 4, as determined and guided by CURATE.AI and approved by the clinical care team.
Study: NCT04935697

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: nVNS
Description: 3x daily treatment of nVNS + SOC

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SOC
Description: Standard of care patient management.

Intervention type: OTHER
Group type: OTHER
Intervention: SOC
Description: Standard of care patient management.
Study: NCT06702228

Intervention type: DIAGNOSTIC_TEST
Intervention: Six minute walk test (6MWT)
Description: Assessment of exercise capacity by the carrying out of a 6MWT at 0, 6 and 12 months.

Intervention type: DIAGNOSTIC_TEST
Intervention: Six minute walk test (6MWT)
Description: Assessment of exercise capacity by the carrying out of a 6MWT at 0, 6 and 12 months.

Intervention type: DIAGNOSTIC_TEST
Intervention: Six minute walk test (6MWT)
Description: Assessment of exercise capacity by the carrying out of a 6MWT at 0, 6 and 12 months.

Intervention type: DIAGNOSTIC_TEST
Intervention: Computer-tomography of the thorax (CT Thorax)
Description: Radiological assessment via CT Thorax, preferably high-resolution CT thorax at baseline on entering the study and at one year. CT images will be collected on study end. CT images in all subjects will be evaluated by three readers blinded to any other interpretation and conforming to ATS-guidelines. Coded data from CT scans will be shared with our collaborator Professor Simon Walsh at Imperial College, London who will use computational methods to identify novel radiologic phenotypes linked to disease behaviour of our patient's fibrotic lung disease.
Study: NCT05837650

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Awareness and Expression Therapy (EAET)
Description: Each EAET session will use an educational lecture, discussion, in-class experiential exercises, and homework assignments. During sessions, participants will be encouraged to identify their stressors and experience and express their avoided or suppressed emotions, using exercises such as emotional disclosure, role playing, and the empty chair technique. Participants will be given homework assignments to complete between sessions, including expressive writing, identification of stressors and avoided emotions, and healthy communication skills practice. The planned topics of the EAET sessions include the emotions-stress-pain model, expressing and experiencing emotions (anger, sadness, hurt, etc.), letting go/forgiveness of self and others, and healthy communication, including assertiveness and intimacy.
Study: NCT04707924

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Er:YAG laser
Description: Treatment of scars with fractional Er:YAG 2940nm laser.
Study: NCT04921930

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artesunate Oral Product
Description: Dose escalation intake of artesunate
Study: NCT04257682

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Bupivacaine is a long-lasting dense sensory-motor block that can last up to four hours. It will be administered once, as part of the spinal anesthetic. The dosage varies based on age and joint, from 6.75 mg to 8.25 mg for the knee, and 7.5 mg to 9 mg for the hip.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine
Description: Ropivacaine is a long-acting local anesthetic that is known for its differential sensory-motor block. It will be administered once, as part of the spinal anesthetic. The dosage varies based on age and joint, from 9 mg to 11 mg for the knee, and 10 mg to 12 mg for the hip.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mepivacaine
Description: Mepivacaine is an intermediate-acting local anesthetic producing shorting and motor-sparing blocks. It will be administered once, as part of the spinal anesthetic. The dosage varies based on age and joint, from 40 mg to 50 mg for the knee, and 45 mg to 55 mg for the hip.
Study: NCT04750122

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: neoadjuvant chemotherapy upon in vitro PTC drug sensitivity screenning
Description: The choice of chemotherapy is based on the PTC drug sensitivity results.
Study: NCT06382987

Intervention type: DRUG
Intervention: Deucravacitinib
Description: According to the product label

Intervention type: DRUG
Intervention: Apremilast
Description: According to the product label