TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05354258

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albendazole
Description: Anthelminthic drugs for the treatment of soil-transmitted helminths

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Praziquantel
Description: Anthelminthic drugs for the treatment of schistosomiasis

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Praziquantel
Description: Anthelminthic drugs for the treatment of schistosomiasis

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amodiaquine
Description: SMC partner drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amodiaquine
Description: SMC partner drug

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Amodiaquine
Description: SMC partner drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sulfadoxine pyrimethamine
Description: SMC partner drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sulfadoxine pyrimethamine
Description: SMC partner drug

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sulfadoxine pyrimethamine
Description: SMC partner drug
Study: NCT06301152

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high intensive laser
Description: high-intensity laser ,three times in a week, for three weeks, 9 session

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: extracorporeal shock wave therapy
Description: extracorporeal shock wave therapy, once a week, for three weeks ,3 times,
Study: NCT06277726

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Emotional freedom technique group
Description: Emotional freedom technique will be applied to women in this group before intrauterine device application.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music group
Description: Women in this group will wear headphones and listen to music throughout the intrauterine device application.

Intervention type: OTHER
Group type: OTHER
Intervention: Control group
Description: No intervention will be applied to women in the control group.
Study: NCT06594354

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ICE
Description: The patients in the intervention group will have ice applied to their mouths for three cycles (the first cycle they met with the researcher and the second and third cycles/an average of two months) when they come for treatment at the hospital with the researcher and at home on the days they do not come for treatment, within the scope of the oral cryotherapy application protocol, they will be monitored by phone and a reminder message will be sent. During chemotherapy, ice cubes will be applied to the patients in the first hour they start receiving chemotherapy and in the same time period, three consecutive ice cubes (each ice cube melts for an average of 1.5-2 minutes/total average of 4.5-6 minutes) and the same application will be repeated three hours later. The patients will be asked to apply ice cubes at home six times (an average of 27-36 minutes/day) at two or three hour intervals for seven days, including the day they receive chemotherapy, and to record their applications on the
Study: NCT05944510

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dextromethorphan
Description: Dextromethorphan 30mg will be administered along with Clozapine (standard of care) in treatment resistant schizophrenia.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo will be administered along with Clozapine (standard of care) in treatment resistant schizophrenia.
Study: NCT04914351

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HY-0102
Description: Multiple dose cohorts, 60 minute IV infusion, every two weeks, 28 days as a cycle
Study: NCT06603103

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SPHERIKA prosthesis
Description: total knee arthroplasty with kinematic alignement with SPHERIKA prosthesis

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ORIGIN prosthesis
Description: total knee arthroplasty with kinematic alignement with ORIGIN prosthesis
Study: NCT06587217

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbidopa 25 mg
Description: Participants will take one 25mg Carbidopa tablet 3 times a day for 10 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbidopa-Levodopa 25/100 mg
Description: Participants will take one 25/100mg carbidopa-levodopa tablet 3 times a day on days 4-6, then increase to 1.5 tablets 3 times a day on days 7-10.
Study: NCT06014866

Intervention type: DEVICE
Intervention: Cardiac pacing
Description: Patient's previously implanted with the INGEVITY+ lead located in the LBBA
Study: NCT05817357

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rensair Compact air purifier unit
Description: Installation of Rensair Compact air purifier (Rensair Ltd.) in the homes of children/young people participating in this study
Study: NCT05095337

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]SHR1459
Description: Patients will receive single dose of orally \[14C\]SHR1459 on Day 1.
Study: NCT06617468

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: computer-aided diagnosis with explainable AI
Description: Perform a same test to estimate the pathologic diagnosis on 200 NBI still images with computer-aided diagnosis with explainable AI.
Study: NCT05372900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Test Product
Description: Whey Protein Isolate with Mulberry leaf extract

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Test Product
Description: Whey Protein Isolate with Mulberry leaf extract

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Product
Description: Wheat Protein Hydrolysate

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Product
Description: Wheat Protein Hydrolysate
Study: NCT04726488

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Periareolar Approach in Minimally Invasive Cardiac Surgery (PAMI Technique)
Description: To study the feasibility and safety of periareolar minimally invasive surgery protocol in patients undergoing periareolar minimally invasive surgery vs. Control group (inframammary approach).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: inframammary approach
Description: To study the feasibility and safety of periareolar minimally invasive surgery protocol in patients undergoing periareolar minimally invasive surgery vs. Control group (inframammary approach).
Study: NCT04755725

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Epidural catheter
Description: epidural catheter inserted pre induction

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: rectus sheath catheter
Description: The surgeon will place one hand inside the abdomen and with the other hand inserted the Tuohy needle through the skin and fascia. The surgeon will feel when the needle tip is just superfacial to interface between the peritoneum and muscle layer and avoid penetration of inferior epigastric artery. The procedure will be repeated on the contralateral
Study: NCT06617468

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: computer-aided diagnosis with deep learning
Description: Perform a same test to estimate the pathologic diagnosis on 200 NBI still images with computer-aided diagnosis with deep Iearning.
Study: NCT06407505

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupressure group
Description: LI4 acupressure applied group.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo group
Description: Group where acupressure was applied to an area 1.5 cm away at the LI4 acupressure point
Study: NCT05453422

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-Acupressure
Description: Acupressure is a therapy method performed with an instrument or hand, fingertip, palm, elbow, knee, thumb relaxation and wrist bands on various points representing the waist organs in order to ensure the continuation and balance of the energy in our body.
Study: NCT04367766

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prosthetically driven implant placement
Description: Insertion of an osseointegrated implant into the bone of anterior maxilla/mandible, following the right prosthetic plan

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prosthetically driven implant placement
Description: Insertion of an osseointegrated implant into the bone of anterior maxilla/mandible, following the right prosthetic plan
Study: NCT05421377

Intervention type: DIAGNOSTIC_TEST
Intervention: clinical assessment
Description: screening of patients at risk for developing unilateral or bilateral lower limb lymphedema
Study: NCT05053399

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Model Series ZXT
Description: Investigational intraocular lens replaces the natural lens removed during cataract surgery in both eyes.
Study: NCT04367766

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prosthetically driven implant placement
Description: Insertion of an osseointegrated implant into the bone of anterior maxilla/mandible, following the right prosthetic plan
Study: NCT04505085

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Dads Healthy Families: Outdoor Education
Description: The intervention will include outdoor education and physical activity opportunities at various outdoor parks. The program will be held one day a week for eight consecutive weeks. Parks and Recreation will facilitate and run the program. Each session will last 60 minutes and include a brief educational discussion and opportunities for various games and activities. Each session will have a special theme relevant to the outdoors. Families will also receive a home toolbox to facilitate activity and learning outside of the program. Feedback on physical activity will be provided at the beginning and the end of the program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Dads Healthy Families: Fitness
Description: The intervention will include physical activity opportunities at a community center. The program will be held one day a week for eight consecutive weeks. Parks and Recreation will facilitate and run the program. Each session will last 60 minutes and include a brief educational discussion and opportunities for various games and activities. Families will also receive a home toolbox to facilitate activity outside of the program. Feedback on physical activity will be provided at the beginning and the end of the program.
Study: NCT05571462

Intervention type: OTHER
Intervention: Activity monitor group
Description: No intervention will be applied. All included patients will be monitored with body-worn physical activity monitors during two periods.
Study: NCT06736925

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Omega-3 Fatty Acids (EPA plus DHA)
Description: DHA+EPA capsules contain purified deep-sea fish oil, made from 100% wild-caught sardines and anchovies with a 3-year shelf life. The capsule shell is made from bovine limed bone with a size of 20 oblongs. Each soft gel capsule contains 480 mg of DHA, 205 mg of EPA, 145 mg of other omega-3 FA, and 10 mg of vitamin E. Participants in the DHA+EPA group will ingest 5 capsules daily \[a total of 3.4 g/d: DHA (2.4 g), EPA (1.0 g)\].

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Organic soybean oil
Description: We will use organic soybean oil pills ) as a placebo condition for the DHA+EPA group. One capsule contains 485 mg of organic soybean oil, including negligible amounts of DHA (1.1 mg), EPA (1.7 mg), and vitamin E (10 mg). Participants will ingest 5 capsules daily. Soybean oil is one of the most widely used vegetable oils in the world. Soybean oil contains polyunsaturated fats and 18-carbon omega-3 FA (total omega-3 FA of 73.9 mg per capsule), but very low levels of DHA and EPA, which makes it an excellent placebo counterpart when evaluating the effects of DHA/EPA. The placebo capsule's shelf life, composition, shape, size as the DHA+EPA active comparator.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Soccer Heading Model
Description: A standardized and reliable soccer heading protocol will be used for the experiment. A triaxial accelerometer (G-force tracker) embedded in a head-band pocket and positioned directly below the external occipital protuberance (inion) to monitor linear and rotational head accelerations. A JUGS soccer machine will be used to simulate a soccer throw-in with a standardized ball speed of 30 mph. The ball speed is similar to when soccer players make a long throw-in from the sideline to mid-field. Soccer players frequently perform this maneuver during practice and games. Subjects will stand approximately 40ft away from the machine to perform the heading. Participants perform 20 headers with 1 header per 30 seconds. The subjects will be instructed to direct the ball back toward the JUGS soccer machine in the air.
Study: NCT06491420

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fixation with arthroscopy
Description: the pipkin fracture is fixed with the help of arthroscopy and percutaneous methods.
Study: NCT06736925

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Soccer Heading Model
Description: A standardized and reliable soccer heading protocol will be used for the experiment. A triaxial accelerometer (G-force tracker) embedded in a head-band pocket and positioned directly below the external occipital protuberance (inion) to monitor linear and rotational head accelerations. A JUGS soccer machine will be used to simulate a soccer throw-in with a standardized ball speed of 30 mph. The ball speed is similar to when soccer players make a long throw-in from the sideline to mid-field. Soccer players frequently perform this maneuver during practice and games. Subjects will stand approximately 40ft away from the machine to perform the heading. Participants perform 20 headers with 1 header per 30 seconds. The subjects will be instructed to direct the ball back toward the JUGS soccer machine in the air.
Study: NCT06739538

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Bobath exercises
Description: Bobath concept, are therapeutic techniques designed to improve motor control and function in individuals with neurological conditions, particularly those with cerebral palsy. These exercises focus on facilitating normal movement patterns, enhancing postural stability, and reducing muscle spasticity. The approach emphasizes individualized treatment, utilizing hands-on techniques to promote movement awareness and encourage the development of functional skills. By reinforcing weak movements and inhibiting overactive ones, Bobath exercises aim to enhance overall motor abilities and improve the quality of life for affected individuals.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Gasotransmitters
Description: such as nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H₂S), are small gaseous signaling molecules that play key roles in various physiological functions, including the regulation of muscle tone and neuroinflammation. In the context of spastic diplegic cerebral palsy (CP), gasotransmitters may help reduce spasticity and pain. Gasotransmitters help reduce spasticity and pain in children with spastic diplegic cerebral palsy through multiple mechanisms: Muscle relaxation and improved blood flow reduce muscle tightness, Anti-inflammatory and neuroprotective properties help minimize the damage that exacerbates spasticity.They also modulate pain pathways, both centrally and peripherally, reducing pain perception.
Study: NCT06737146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT027 cells suspension
Description: MT027: CRISPR/Cas9 edited B7H3-specific allogeneic CAR-T cells
Study: NCT06739512

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extensive Electro-Anatomical Guided Ablation
Description: Ablation using PFA. Combination of anatomical and electrogram-guided ablation techniques.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Anatomical Guided Ablation
Description: Ablation using PFA. Guided by anatomical landmarks without potential mapping
Study: NCT05796089

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Thoracic Radiotherapy
Description: Participants will receive thoracic radiotherapy to a dose of 30 Gray (Gy) in 10 fractions (3 Gy per day) concurrently with cycle 3 or 4 of chemo-immunotherapy (Group 1).~Participants who are unsuitable for concurrent radiotherapy may receive consolidation radiotherapy. Consolidation thoracic radiotherapy will be administered to a dose of 30 Gy in 10 fractions, following 4 cycles of chemo-immunotherapy (Group 2).~Treatment fractions will be delivered daily, where treatment should be completed within 15 days (9-10 fractions a fortnight).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide with Carboplatin or Cisplatin
Description: The chemotherapy in this study is a standard treatment for extensive-stage small-cell lung cancer (EC-SCLC). The combination of chemotherapy (etoposide + carboplatin or etoposide + cisplatin) which the participant will receive is dependent on what is standard at the treatment centre.~Chemotherapy will be administered via an intravenous infusion every 3 weeks (21 days) for 4 cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: The immunotherapy in this study is a standard treatment for ES-SCLC.~Participants will receive a dose of 1500 mg of Durvalumab via an intravenous infusion every 3 weeks (21 days) for 4 cycles, concurrently with chemotherapy.~A 1500 mg maintenance dose of Durvalumab will administered every 4 weeks after completion of chemotherapy (monotherapy).
Study: NCT05170191

Intervention type: BEHAVIORAL
Intervention: Sleep Deprivation
Description: The participants will stay awake for 24 hours.
Study: NCT05394545

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nu-V3
Description: The Nu-V3 device provides a continuous flow of intermittent, low frequency electrical pulses to the ear's specific cranial nerve endings. This treatment is delivered 24 hours a day for the first 12 weeks, then is delivered two weeks on, one week off for the following 12 weeks.
Study: NCT05417828

Intervention type: DEVICE
Intervention: Emulation of Active Daily Living tasks with a robotic device (SPINDLE)
Description: SPINDLE will provide an assistive and resistive force to aid in rehabilitating the subject's upper limb
Study: NCT06333756

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross education
Description: Cross education training of the biceps brachii (12 rep./set, 3sets, 60%MVIC,180°/s, eccentric contraction)
Study: NCT05117632

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALTO-100 PO tablet
Description: one tablet twice daily
Study: NCT04881656

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Help is in Your Hands
Description: HIIYH is a set of 16 online educational modules for caregivers of children with social-communication delays or elevated likelihood of ASD.
Study: NCT06419309

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: Four different dietary interventions are planned.~* Gluten-free, lactose-free diet,~* Diet enriched with Aronia Melanocarpa,~* Gluten-free, lactose-free and enriched with Aronia Melanocarpa diet,~* Healthy diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: Four different dietary interventions are planned.~* Gluten-free, lactose-free diet,~* Diet enriched with Aronia Melanocarpa,~* Gluten-free, lactose-free and enriched with Aronia Melanocarpa diet,~* Healthy diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: Four different dietary interventions are planned.~* Gluten-free, lactose-free diet,~* Diet enriched with Aronia Melanocarpa,~* Gluten-free, lactose-free and enriched with Aronia Melanocarpa diet,~* Healthy diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: Four different dietary interventions are planned.~* Gluten-free, lactose-free diet,~* Diet enriched with Aronia Melanocarpa,~* Gluten-free, lactose-free and enriched with Aronia Melanocarpa diet,~* Healthy diet
Study: NCT05812495

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Esophagogastric Side to Side Anastomosis
Description: Esophagogastric Side to Side Anastomosis

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Esophagogastric End to Side Anastomosis
Description: Esophagogastric End to Side Anastomosis
Study: NCT05901181

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Laughter Yoga
Description: Laughter yoga is a childlike practice where group members make eye contact with each other.~It is a breath yoga practiced by imitating games and fake laughing. Brain the effects of real laughter on the body, as it cannot distinguish between fake and real laughter.~showing positive effects. It consists of sessions lasting at least 20 minutes and an average of 45 minutes.
Study: NCT06481540

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Expiratory muscle strength training + SpiroGym application
Description: Participants will performe an intensive home-based expiratory muscle training programme using an Expiratory Muscle Trainer (EMST150; Aspire Products, LLC, United States), which provide a pressure- threshold range from 30 to 150 cmH20. EMST therapy sessions will be completed at home on 5 days of the patients choosing per week. Participants will be instructed to perform five sets of five forceful expirations coupled with SpiroGym app. per training session for 8 weeks (intensive training period). After this period, participants will perform an additional 16 weeks of maintenance EMST. EMST therapy sessions will be completed at home on two days (minimum) of the participant's choosing each week.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Expiratory muscle strength training
Description: Participants will performe an intensive home-based expiratory muscle training programme using an Expiratory Muscle Trainer (EMST150; Aspire Products, LLC, United States), which provide a pressure- threshold range from 30 to 150 cmH20. EMST therapy sessions will be completed at home on 5 days of the patients choosing per week. Participants will be instructed to perform five sets of five forceful expirations per training session for 8 weeks (intensive training period).After this period, participants will perform an additional 16 weeks of maintenance EMST. EMST therapy sessions will be completed at home on two days (minimum) of the participant's choosing each week.
Study: NCT04564339

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ravulizumab
Description: Dosages (loading and maintenance) will be based on the participant's body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ravulizumab
Description: Dosages (loading and maintenance) will be based on the participant's body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ravulizumab
Description: Dosages (loading and maintenance) will be based on the participant's body weight.
Study: NCT06218524

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Haloperidol Tablets
Description: Haloperidol tablet 6mg, Oral, Triple/Day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide, 150mg/kg, Oral, Once/Day, 5/28 days