TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04413097

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Delayed Cord Clamping with Low Oxygen concentration
Description: During delayed umbilical cord clamping of 90 seconds, breathing assistance with CPAP/PPV and low oxygen concentration (FiO2 0.30) will be provided.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Delayed Cord Clamping with High Oxygen concentration
Description: During delayed umbilical cord clamping of 90 seconds, breathing assistance with CPAP/PPV and high oxygen concentration (FiO2 1.0) will be provided.
Study: NCT06356051

Intervention type: DEVICE
Intervention: Echocardiography
Description: cardiovascular evaluation

Intervention type: DEVICE
Intervention: Echocardiography
Description: cardiovascular evaluation
Study: NCT04888169

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SMART Mobile App - Attention Bias Modification
Description: ABM involves placing the probe behind the neutral stimulus on 100% of the trials.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SMART Mobile App - Attention Bias Modification
Description: ABM involves placing the probe behind the neutral stimulus on 100% of the trials.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SMART Mobile App - Attention Control Training
Description: ACT involves placing the probe behind the neutral stimulus on 50% of trials, and behind the threat stimulus on 50% of trials.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SMART Mobile App - Attention Control Training
Description: ACT involves placing the probe behind the neutral stimulus on 50% of trials, and behind the threat stimulus on 50% of trials.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: SMART Mobile App - Placebo Training
Description: Placebo training only includes neutral stimuli.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: SMART Mobile App - Placebo Training
Description: Placebo training only includes neutral stimuli.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SMART Mobile App - Control
Description: Participants will only answer questions.
Study: NCT05354271

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-intensity interval training
Description: Patients will cycle or walk/run four intervals of four-min at high intensity with the aim to reach 80-90% of peak oxygen consumption, 90-95% of peak heart rate, 15-17 Borg scale, shortness of breath). Each interval is separated by a three-min active recovery, at 50-60% of peak oxygen consumption or 70-75% of peak heart rate. Total exercise time will be 38 min including the warm-up and cool-down.
Study: NCT06186778

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: secondary colonoscopy
Description: After the routine colonoscopy, a repeat colonoscopy of the sigmoid colon is performed

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional colonoscopy
Description: It starts from the rectum and progresses forward to the cecum, with observations made during withdrawal: from the cecum, ascending colon, transverse colon, descending colon, and sigmoid colon to the rectum.
Study: NCT05766306

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic Blend
Description: Participants will be taking 1 sachet a day, 3 billion CFU.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be taking 1 sachet a day.
Study: NCT04149145

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: M4344+Niraparib
Description: The first phase will be a 3+3 design of fixed dose Niraparib by mouth (PO) every day (QD) and M4344 will be escalated from 100-200 mg PO QD (28-day cycle). There will be a 4-week lead in with niraparib only.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: M4344+Niraparib
Description: In the second phase eligible patients will receive combination Niraparib + the determined dose of M4344 from the first phase.
Study: NCT04861766

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: STYLAGE® L
Description: Injection in both NLFs

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator
Description: Injection in both NLFs
Study: NCT06258148

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TG103
Description: TG103 injection, 7.5mg, 15 mg, SC, once a week

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TG103
Description: TG103 injection, 7.5mg, 15 mg, SC, once a week
Study: NCT06238882

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nitroglycerin
Description: Patients in the intervention group will receive four 8mg-patches (36 mg final dose) of transdermal nitroglycerin with 10 mg release in 24 hours, for 24 hours with 12-hour rest intervals (to avoid receptor saturation) during treatment with radiation therapy (30 Gy in 10 fractions, or 10 days of treatment).
Study: NCT04362228

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Whole-body exercise
Description: 10-week one-on-one, virtual, whole-body exercise class, 3x/week, focused on increasing respiratory rate through moderate-intensity aerobic exercises.
Study: NCT06392854

Intervention type: DRUG
Group type: OTHER
Intervention: Insulin
Description: 2 dose insulin infusion 4 hours

Intervention type: DRUG
Group type: OTHER
Intervention: Insulin
Description: 2 dose insulin infusion 4 hours
Study: NCT06058624

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Veteran ACT for Chronic Pain (VACT-CP)
Description: Participants receive 7 online modules, provided as weekly sessions that feature Coach Anne as a virtual, animated treatment guide. All content is presented interactively, through text-based conversations with Coach Anne. Veterans will hear what Coach Anne says and respond to her using text-based dialogue options that will trigger different responses from Coach Anne as the conversation progresses, to allow the system to responsively interact in a personalized manner with the Veteran. Veterans will also be presented with videos (e.g., Veteran narratives, metaphors), in-module assessments (e.g., values assessments), and interactive opportunities for goal setting.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online Pain School
Description: Participants will receive 7 modules (15 to 20 minutes each) of content based on a common non-ACT based VA treatment option, Pain School. The adaptation used for this study, Online Pain School, will support Veterans' self-management of their chronic pain by providing informational videos on chronic pain and its health impacts, short behavioral exercises to help with pain management, and psychoeducation on different wellness techniques for their pain management toolbox.
Study: NCT05354271

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Moderate-intensity continuous training
Description: Patients will cycle or walk/run continuously at moderate intensity (50-60% of peak oxygen consumption, 70-75% of peak heart rate) for 37 min. Total exercise time will be 47 min for the Moderate-intensity continuous training group including warm-up and cool-down (isoenergetic compared to high-intensity interval training).
Study: NCT05252507

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Paint Night
Description: There will be 8 Sessions (4 paint nights and 4 educational sessions alternating weeks). For the painting sessions, participants will paint for 45 minutes and then participate in a combined presentation/discussion session (45 minutes). For the educational sessions, they will attend a 30-minute presentation presented by a researcher on heart health and then have the opportunity to discuss with the researcher and other members of the group (60 minutes).
Study: NCT05791201

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-264
Description: Allogeneic human stem cell-derived islets.
Study: NCT06484387

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social interaction
Description: Participants are required to speak to one another. Participants are given various topics of conversation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social interaction
Description: Participants are required to speak to one another. Participants are given various topics of conversation.
Study: NCT06096857

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Roseomonas mucosa (RSM2015) and Cardamom seeds
Description: Freeze dried packet to be reconstituted in water

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (sucrose)
Description: Freeze dried packet to be reconstituted in water
Study: NCT06258148

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo, SC, once a week

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo, SC, once a week
Study: NCT05535478

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: STRIDE
Description: a. Targeted providers for STRIDE program: i. Clinical staff at the LTCF who participate in deprescribing at the facilities (physicians (MDs), physician's assistants (PAs), nurse practitioners (NPs), clinical pharmacists): clinical staff members caring for LTCF residents with ADRD and diabetes at 6 LTCFs in the Ohio and Michigan areas will be invited via email from the LTCF leadership to participate in the STRIDE education program. The STRIDE program consist of practical algorithms and educational material, which they are free to view at any time, and participation in 2 webinars and monthly telementoring calls
Study: NCT06048601

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-florbetaben PET/CT
Description: 18F-florbetaben positron emission tomography/computed tomography
Study: NCT05113537

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Given Orally
Study: NCT06421376

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cardonilizumab
Description: Two cycles of Inductive therapy： nab-paclitaxel 250mg/ m2+cisplatin 75mg/ m2+Cardonilizumab 10mg/kg，ivgtt，3 weeks per cycle for 2 cycles
Study: NCT05113537

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Given Orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutetium Lu 177-PSMA-617
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutetium Lu 177-PSMA-617
Description: Given IV
Study: NCT06262724

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Breast auto-augmentation
Description: Single group assignment. All patients included were subjected to utilizing chest wall perforator flaps for breast reshaping.
Study: NCT04854928

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LTX-109 gel, 3%
Description: A Single dose of LTX-109 gel will be applied topically to both nostrils by a qualified health professional. A large drop of IMP will be applied into each nostril and distributed to cover the whole area of the nostril.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo gel
Description: A Single dose of placebo gel will be applied topically to both nostrils by a qualified health professional. A large drop of IMP will be applied into each nostril and distributed to cover the whole area of the nostril.
Study: NCT04130165

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Matched donor human milk
Description: Milk from donor mothers will be sorted according to their secretor status. This milk will be provided to infants in the intervention (experimental) arm.
Study: NCT06420921

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Speech in noise comprehension test
Description: Speech in noise comprehension tests consisting of listening to a speech source and one or more competing sources (noise, speech or sound cues) simultaneously. The volunteers will have to repeat the speech source in order to assess intelligibility for each situation, as a function of the intensity ratio of the two sources (SNR).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Speech in noise comprehension test
Description: Speech in noise comprehension tests consisting of listening to a speech source and one or more competing sources (noise, speech or sound cues) simultaneously. The volunteers will have to repeat the speech source in order to assess intelligibility for each situation, as a function of the intensity ratio of the two sources (SNR).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Objective tests of perception of ambient sound cues in noise
Description: Tests of perception of the sound environment consisting of listening to a source of noise, sound cues and a competing source of speech simultaneously. The volunteers will have to identify sound cues in order to assess the ability to perceive the sound environment for each situation, depending on the intensity ratio of the different sources.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Objective tests of perception of ambient sound cues in noise
Description: Tests of perception of the sound environment consisting of listening to a source of noise, sound cues and a competing source of speech simultaneously. The volunteers will have to identify sound cues in order to assess the ability to perceive the sound environment for each situation, depending on the intensity ratio of the different sources.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Subjective tests of perception of ambient sound cues in noise
Description: Tests of perception of the sound environment consisting of listening to a source of noise, sound cues and a competing source of speech simultaneously. Using a simple interface, the volunteers will have to identify the intensity ratio of the sources that they consider to be the best compromise between understanding speech and perceiving the sound environment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Subjective tests of perception of ambient sound cues in noise
Description: Tests of perception of the sound environment consisting of listening to a source of noise, sound cues and a competing source of speech simultaneously. Using a simple interface, the volunteers will have to identify the intensity ratio of the sources that they consider to be the best compromise between understanding speech and perceiving the sound environment.
Study: NCT05578820

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Stimotimagene copolymerplasmid
Description: Gene therapy drug, Intratumoral administration

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Stimotimagene copolymerplasmid
Description: Gene therapy drug, Intratumoral administration
Study: NCT05311930

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 2.5mg/d Hetrombopag
Description: After the subjects signed the informed consent and passed the screening, they entered the treatment period and received a starting dose of 2.5 mg/d of Hytrombopag. During the treatment process, the clinician adjusted the drug dose according to the patient's own conditions. The maximum drug dose was 7.5 mg qd, 28 d Evaluate efficacy and safety after completion;
Study: NCT05269108

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fluoroscopy-free RIRS
Description: RIRS for renal stone under direct visualization, without fluoroscopy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard RIRS
Description: RIRS for renal stone under fluoroscopy-guidance
Study: NCT05578820

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Stimotimagene copolymerplasmid
Description: Gene therapy drug, Intratumoral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ganciclovir
Description: Antiviral drug, Intravenous administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ganciclovir
Description: Antiviral drug, Intravenous administration
Study: NCT05020275

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood Samples
Description: * Samples for ctDNA blood concentration and osimertinib plasma concentration~* Sample for genetic polymorphisms
Study: NCT05711472

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: birth ball exercise
Description: birth ball exercise used in childbirth
Study: NCT05578820

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ganciclovir
Description: Antiviral drug, Intravenous administration
Study: NCT05571397

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dexcom G6
Description: Continuous Glucose Monitor
Study: NCT05692726

Intervention type: OTHER
Intervention: Patients
Description: Patients will get study-specific measurements within first 5 days of standard of care treatment of hyponatremia or until discharge
Study: NCT04843098

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TL117
Description: TL117 capsules orally once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel (80 mg/m2) administered intravenously (IV) on Days 1, 8, and 15 of a 28-day treatment cycle.
Study: NCT06510894

Intervention type: DRUG
Intervention: Sotagliflozin
Description: Sodium-glucose cotransporter-1/2 inhibitor
Study: NCT06416462

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: antimicrobial photodynamic therapy
Description: When starting the research, all wounds, regardless of the study group, will be cleaned with 0.9% saline solution (SF0.9%), using a 40x12 needle and a 500ml bottle of SF0.9%, in order to maintain pressure. for equal cleaning of all wounds and a hydrofiber plate with silver was used as standard coverage. Experimental group (n=45): When starting the intervention, all services in both groups will follow the cleaning standard described previously. In the aPDT group, 1% methylene blue will be used as a photosensitizer applied with the aid of a syringe (with a pre-irradiation time of 5 minutes), 6 J of laser will be applied.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: antimicrobial photodynamic therapy
Description: When starting the research, all wounds, regardless of the study group, will be cleaned with 0.9% saline solution (SF0.9%), using a 40x12 needle and a 500ml bottle of SF0.9%, in order to maintain pressure. for equal cleaning of all wounds and a hydrofiber plate with silver was used as standard coverage. Experimental group (n=45): When starting the intervention, all services in both groups will follow the cleaning standard described previously. In the aPDT group, 1% methylene blue will be used as a photosensitizer applied with the aid of a syringe (with a pre-irradiation time of 5 minutes), 6 J of laser will be applied.
Study: NCT05219110

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Infusion of 200% maintenance fluids as balanced crystalloid IV solution
Description: Infusion of 200% of maintenance fluids x 24 hours provided, ideally, as a balanced crystalloid (PlasmaLyteTM, Ringer's Lactate) IV solution. Electrolytes and dextrose may be administered as required and desired by the clinical care team; customized solutions are permitted if so desired. Intravenous fluid solutions containing \< 130 mEq/L sodium may increase risk for hyponatremia and may be less effective in achieving intravascular volume expansion and should be avoided.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oral fluids; infusion of up to 110% maintenance fluids as balanced crystalloid IV solution
Description: Administration of less than or equal to 110% of maintenance fluids as oral or balanced crystalloid IV solution.
Study: NCT06036407

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Hearing test
Description: Participants visit a local hearing aid shop to assess their hearing function
Study: NCT05119283

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scraping and straightening of the crown and root and rinsing with mouthwashes
Description: Patients will answer a questionnaire about their socioeconomic conditions, and soon after undergoing the examination for bleeding, probing, clinical attachment level, probing depth and plaque index for initial clinical evaluation. Basic periodontal treatment will be carried out with the same operator (blind to the treatments performed), with complete removal of plaque and calculi, prophylaxis with pumice and prophylactic paste and oral hygiene instructions. After basic periodontal treatment, patients will be randomly divided based on a draw with closed, opaque and non-translucent envelopes, into 3 groups according to the supporting treatments: G1 - patients who will receive mouthwashes with saline solution; G2 - patients who will be rinsed with 0.12% chlorhexidine and G3 - patients who will be treated with PHTALOX®.
Study: NCT06400823

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR+TENS
Description: During the invention, patients will be in VR scenarios and play task-oriented games, interacting with elements that appear in the virtual world, to improve mobility and functional independence of the upper limbs.~The task-oriented games will target different components depending on the disability of the patient.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional rehabilitation
Description: Patients will perform conventional upper-limb stroke rehabilitation. The movement performed will be comparable with the movement performed in the VR+TENS group
Study: NCT06408103

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-component, transdisciplinary and multifocal intervention for the cognition
Description: Multi-component intervention (12 weeks, twice/week, with professional support at home)~Physical activity for the patient: dual training, strength, balance, with intensity increase monthly, plus moderate walking of 30 minutes/day, 5 days per week.~Nutritional advice for the patient: Month 1- reduction of added sugars and processed carbohydrates. Month 2- increase consumption of healthy fats and reduction of saturated fats; Month 3- increase in consumption of fruits and vegetables, and a monthly group practical workshop.~Cognitive training for the patient: activities focused on orientation, attention and concentration, working memory, mathematical reasoning, language, visual construction, executive functions, and reminiscence therapy.~Accompaniment for the family member: Activities aimed at care and self-care, understanding cognitive deterioration and its progression, support for patient adherence to the intervention, and activities in groups once a week.
Study: NCT05807477

Intervention type: DEVICE
Intervention: Pulse Oximeter
Description: OLV-4202 pulse oximeter (SW version: 01-15)