TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04230772

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Natural Orifice Specimen Extraction Surgery
Description: In the experimental group, patients will be performed robotic colorectal resection with natural orifice specimen extraction.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Robotic-assisted Surgery
Description: In the active comparator group, patients will be performed traditional robotic-assisted colorectal resection.
Study: NCT05733182

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 6500K Reading lamp
Description: Reading lamp with custom-made circuitry to emit light of 6500K colour temperature
Study: NCT05979896

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard age based SPAQ administration for SMC
Description: Sulfadoxine-pyrimethamine and amodiaquine (SPAQ) is administered in standard WHO approved age based regimens as used in Seasonal Malaria Chemoprevention Programmes.~Sulphadoxine is a slowly eliminated sulphonamide. It is used in a fixed dose combination of 20 parts sulphadoxine with 1 part pyrimethamine given orally or intramuscularly.~Sulphadoxine is readily absorbed from the GIT. It is widely distributed in body tissues and fluids and crosses the placenta into foetal circulation. It is also readily detectable in breast milk. It is excreted predominantly as the unchanged drug. AQ Amodiaquine is a Mannich base 4 amino-quinoline that interferes with parasite haem detoxification. It is more effective than chloroquine in both chloroquine sensitive and resistant P. falciparum infections. However, there is cross-resistance between chloroquine and amodiaquine.~It is readily absorbed in the GIT and rapidly converted in the liver to the active metabolite, desethylamodiaquine.
Study: NCT04945564

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Oxygen therapy and physical therapy
Description: Patients receive oxygen therapy and physical therapy

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen therapy
Description: Patients receive oxygen therapy
Study: NCT05588934

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine Gum
Description: Commercially available caffeinated gum that contains 100mg of caffeine per piece of gum.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine Gum
Description: Commercially available caffeinated gum that contains 100mg of caffeine per piece of gum.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine Gum
Description: Commercially available caffeinated gum that contains 100mg of caffeine per piece of gum.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine Gum
Description: Commercially available caffeinated gum that contains 100mg of caffeine per piece of gum.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Gum
Description: Commercially available non-caffeinated gum.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Gum
Description: Commercially available non-caffeinated gum.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Gum
Description: Commercially available non-caffeinated gum.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Gum
Description: Commercially available non-caffeinated gum.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Gum
Description: Commercially available non-caffeinated gum.
Study: NCT04497532

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet as suited for gestational diabetes mellitus
Description: Diet that consists of complex carbohydrates, and a regimen that includes 6 meals per day, as tailored gor gestational diabetes.
Study: NCT05472571

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Forest bathing
Description: The intervention consists of 11 consecutive sessions of forest bathing (one session per week), each one lasting about 2 hours. Each session involves an easy walk through a forest area, interspersed with non-intrusive activities of contact with the surrounding nature aimed at fostering mindfulness and the use of the five senses.
Study: NCT05233215

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GROW (Glioma Specialists Reaching Out With Support) Support Program
Description: Follow-up survivorship care plan for patients and caregivers
Study: NCT05946694

Intervention type: OTHER
Intervention: intubation in manikin
Description: Evaluation of 3 videolaryngoscopes under simulated out-of-hospital conditions by people without clinical experience on a manikin model
Study: NCT05857592

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Adaptive functioning self-report questionnaire
Description: A self-report questionnaire for assessing level of adaptive functioning

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Adaptive functioning self-report questionnaire - adapted
Description: A self-report questionnaire for assessing level of adaptive functioning, adapted to the communication level of the participant
Study: NCT06237777

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: SKG0106 intravitreal injection dose level 1, 2 or 3
Description: SKG0106 is a recombinant adeno-associated virus (rAAV) vector-based in vivo gene therapeutic product.
Study: NCT05397847

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Rational Drug Use in Elderly Individuals~1. Training: Through home visits, an average of 30 minutes of training will be given to elderly individuals (drugs, rational drug use, the importance of rational drug use, and what the elderly should do for rational drug use). Question-answer method and visual materials will be used in the training.~2. Training: An average of 20 minutes of training will be given, including a brief repetition of the topics covered in the first training, via a home visit. Visual materials will be used in the training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rational Drug Use Guide
Description: At the end of the first training, a rational drug use guide will be given to elderly individuals, including the topics explained.
Study: NCT05695963

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical assessment
Description: RLS history, RLS treatments, and International Restless Legs Syndrome Rating Scale (IRLSRS) will be recorded

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: auto-questionnaires
Description: To evaluate sleep quality, daytime somnolence and mood disorders (Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS) and Hospital Anxiety and Depression Scale (HADS)).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ecological Momentary Assessment (EMA)
Description: 4 electronic interviews administred per day during 14 days by a study-dedicated Android OS smartphone

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: activity-rest cycle
Description: To further investigate the mutual influence of sleep quality on RLS symptoms and mood, the activity-rest cycle will be monitored by wearable actigraph to be placed on the non-dominant wrist during a period of 13 days and 14 nights.
Study: NCT06236048

Intervention type: PROCEDURE
Intervention: MRI scan
Description: 7 Tesla MRI scan

Intervention type: PROCEDURE
Intervention: MRI scan
Description: 7 Tesla MRI scan

Intervention type: PROCEDURE
Intervention: MRI scan
Description: 7 Tesla MRI scan

Intervention type: PROCEDURE
Intervention: PET-MR scan
Description: 18F-fluorodeoxyglucose PET-MR scan

Intervention type: PROCEDURE
Intervention: PET-MR scan
Description: 18F-fluorodeoxyglucose PET-MR scan

Intervention type: PROCEDURE
Intervention: PET-MR scan
Description: 18F-fluorodeoxyglucose PET-MR scan
Study: NCT05366114

Intervention type: OTHER
Intervention: No intervention, additional video data collection only
Description: No intervention will be used. Consenting participants will have video recordings taken during their exam of joint hypermobility which will be analyzed at a later time
Study: NCT05397847

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medicine Box
Description: Elderly individuals will be given a medicine box large enough to be carried in the pocket when appropriate, so that the elderly people do not forget their medicines and use them regularly, with a 7-day medicine compartment that organizes their medicines and a daily (morning, noon, evening and night) medicine box.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counseling
Description: After the training, counseling services will be given to elderly individuals regarding rational drug use. Within the scope of the counseling service, it will be ensured that the drugs used by the elderly person are regulated and their questions about rational drug use will be answered.
Study: NCT06465771

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Youth-led NCD risk reduction intervention
Description: With the help of Youth (students of grades 9 and 10), their parents and other stakeholders, including teachers, headteachers, and canteen staff through qualitative interviews, we will develop an intervention focuses on NCD risk reduction among younger peers (students of grades 5 and 6). A nutritionist will train the youth on how to deliver the intervention among their younger peers.
Study: NCT06171516

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iCBT
Description: All participants will undergo 10 guided therapy sessions (once-weekly) with each session lasting 20 minutes. The therapy module will be given as an online self-learning source via videos in a website specifically developed for this training. The videos will divide the module content into several parts with each video lasting about 10 minutes.
Study: NCT04699370

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cognition-targeted exercise
Description: All Standardized physical therapy exercises will be performed in a time-contingent .~Goal setting is essentially done together with the patient, focussing on functionality instead of fatigue relief. Progression to a next level of (more difficult) exercises will be preceded by an intermediate phase of motor imagery.~The treating physical therapist will be advised to address patients' cognitions about their problems during the cognition-targeted exercise training, so that patients will have positive perceptions regarding their illness and treatment outcome.~The treating physical therapist will be advised to discuss the patient's perceptions about each exercise. This include discussion of the anticipated consequences of the exercises and challenging the patient's cognitions in relation to the exercises

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral therapy
Description: In the first and second sessions, patients will learn about fatigue-related symptoms as well as Cognitive behavioral therapy and its effectiveness. The third and fourth sessions will be devoted on the introduction of behavioral strategies. The fifth session will introduce cognitive strategies to decrease fatigue. The last three sessions will be about how to adopt the proposed strategies consistently.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive behavioral therapy
Description: In the first and second sessions, patients will learn about fatigue-related symptoms as well as Cognitive behavioral therapy and its effectiveness. The third and fourth sessions will be devoted on the introduction of behavioral strategies. The fifth session will introduce cognitive strategies to decrease fatigue. The last three sessions will be about how to adopt the proposed strategies consistently.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standardized physical therapy
Description: The standardized physical therapy will consist of eight half-hour individualized face to face physiotherapy sessions, over a 4-week period. this program will consist of twice-weekly supervised general aerobic, strengthening and flexibility exercise sessions .This exercise program is reflective of the general exercises typically undertaken within routine clinical practice.
Study: NCT06054945

Intervention type: PROCEDURE
Intervention: SIFIB (suprainguinal fascia iliaca block)
Description: Ultrasound guided Suprainguinal Fascia Iliaca Block for Knee Arthroplasty Patients

Intervention type: PROCEDURE
Intervention: SIFIB (suprainguinal fascia iliaca block)
Description: Ultrasound guided Suprainguinal Fascia Iliaca Block for Knee Arthroplasty Patients

Intervention type: OTHER
Intervention: IPACK (Interspace between the popliteal artery and capsule of the posterior knee )
Description: Ultrasound guided IPACK (Interspace between the popliteal artery and capsule of the posterior knee ) Block for Knee Arthroplasty Patients

Intervention type: DEVICE
Intervention: Patient controlled anagesia device
Description: Those who were administered opioids with PCA as rescue analgesic in the postoperative analgesia plan on the selected dates will be included in the study.

Intervention type: DEVICE
Intervention: Patient controlled anagesia device
Description: Those who were administered opioids with PCA as rescue analgesic in the postoperative analgesia plan on the selected dates will be included in the study.
Study: NCT06205147

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Elastic Band
Description: Using the newly patented product, the Muscle Exercise and Falling Prevention Elastic Strap (Patent Certificate No. M585601), the procedure involves securing the elastic strap to a high-back chair to administer elastic band intervention exercises for patients.Guided by continuous contextual action demonstration videos, participants will engage in the elastic band resistance intervention twice a day, each session lasting 20 minutes, over a span of five days. These videos are designed to provide a continuous contextual demonstration, incorporating them within the video itself.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Elastic Band
Description: Using the newly patented product, the Muscle Exercise and Falling Prevention Elastic Strap (Patent Certificate No. M585601), the procedure involves securing the elastic strap to a high-back chair to administer elastic band intervention exercises for patients.Guided by continuous contextual action demonstration videos, participants will engage in the elastic band resistance intervention twice a day, each session lasting 20 minutes, over a span of five days. These videos are designed to provide a continuous contextual demonstration, incorporating them within the video itself.
Study: NCT04399343

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine hydrochloride (200 μg/2 ml) is diluted with normal saline to 50 ml and is continuously intravenous infused at a rate of 0.025 ml/kg/hour (dexmedetomidine 0.1 μg/kg/hour). The intravenous infusion begins immediately after enrollment until 08:00 AM on the postoperative day one.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Normal saline is also diluted with normal saline to 50 ml and is continuously intravenous infused at a rate of 0.025 ml/kg/hour, which is the same with the dexmedetomidine group. The intravenous infusion begins immediately after enrollment until 08:00 AM on the postoperative day one.
Study: NCT04650399

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Active
Description: Single intramuscular vaccination on Day 1 with VLA1553, a lyophilized live-attenuated Chikungunya vaccine candidate 1x10E4 TCID50 per dose

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single intramuscular vaccination on Day 1 with Phosphate-Buffered Saline (PBS) as placebo
Study: NCT05438836

Intervention type: RADIATION
Intervention: online adaptive radiotherapy
Description: Online adaptive radiotherapy compared to standard non-adaptive Image-Guided Radiotherapy
Study: NCT04821817

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: peribulbar anesthesia with 10 ml local anesthetic mixture composed of 4 ml of plain bupivacaine 0.5%, 4 ml of lidocaine 2% containing 50 IU, and 2 ml normal saline.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rocuronium
Description: peribulbar anesthesia with 10 ml local anesthetic mixture composed of 4 ml of plain bupivacaine 0.5%, 4 ml of lidocaine 2% containing 50 IU, and 0.06 mg/kg of rocuronium in 2 ml normal saline.
Study: NCT05535426

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tetranite Implant Stabilization Material
Description: Dental adhesive for increased implant stabilization
Study: NCT05030051

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SkinPen Precision System
Description: Microneedling is a relatively new, minimally invasive technique originally developed for skin rejuvenation. Controlled micro-injury to the dermis via the application of several small needles connected to a motorized device stimulates the wound healing process, resulting in the formation of new tissue and blood vessels. The SkinPen by Crown Laboratories is an FDA-cleared microneedling device proven to improve the appearance of acne scars This study evaluates the clinical performance of the SkinPen device for the treatment of signs of aging on the back of the hand. We hypothesize that the SkinPen device will produce a significant improvement in dorsal hand appearance at 3 month post treatment visit, when compared with baseline scores. The assessments will be based on the Clinician's Global Aesthetic Improvement Scale, and the Subject's Global Aesthetic Improvement Scale at the 3 month post treatment visit.
Study: NCT06020950

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Low-calorie diet with the use of placebo pearls (containing sunflower oil)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Omega-3 supplementation
Description: Low-calorie diet with the use of marine omega-3 pearls (containing 1200 mg eicosapentaenoic acid + 600 mg docosahexaenoic acid/day)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chia seed
Description: Low-calorie diet with the consumption of 30 grams of powdered chia seeds
Study: NCT05266703

Intervention type: OTHER
Group type: OTHER
Intervention: Isotopically labelled iron sulfate 15mg
Description: test drink: water containing isotopic iron solution with vitamin C
Study: NCT05602753

Intervention type: BEHAVIORAL
Intervention: Lifestyle Counseling
Description: Referring to Stop smoking hotline, given pamphlets to encourage quitting smoking, pharmacy guidance, and possible referral to smoking cessation clinic.
Study: NCT05097391

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Warm-up (5 minutes)
Description: Participants will benefit from passive stretches of hamstrings, calf muscles including a range of motion (ROM) exercise to the lower limbs as mat exercises.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Warm-up (5 minutes)
Description: Participants will benefit from passive stretches of hamstrings, calf muscles including a range of motion (ROM) exercise to the lower limbs as mat exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy exercise (15 minutes)
Description: The conventional treatments will be active-assisted and free active exercises to the lower limbs on the mat for five (5) minutes. This will be followed by strength training such as sit-to-stand exercises for five (5) minutes and squatting exercises for five (5) minutes prior to the over-ground training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conventional physiotherapy exercise (15 minutes)
Description: The conventional treatments will be active-assisted and free active exercises to the lower limbs on the mat for five (5) minutes. This will be followed by strength training such as sit-to-stand exercises for five (5) minutes and squatting exercises for five (5) minutes prior to the over-ground training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Over-ground training with lower limb loading (15-25 minutes)
Description: Participants will perform the over-ground training exercise with an external 1.5kg load on the paretic lower limb placed 2cm above the ankle joint. Before commencing the over-ground training, all the participants will observe a pre-exercise rest period of about two (2) minutes during which their heart rate and blood pressure measurements will be recorded.~The over-ground training will involve the patients walking within a demarcated path. Each participant will be instructed to stand and walk 15meters to and fro for five (5) minutes after which they will be asked to stop and rest for two (2) minutes. The over ground training exercise will be repeated 3 times in the first 2 weeks of the training (15 minutes); 4 times in weeks 3-4 of the training (20 minutes); and 5 times in weeks 5-8 of the training (25 minutes).
Study: NCT04749680

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PD cycler Silencia
Description: Treatment for 2 weeks either with PD-Night or Homechoice PD cycler (Comparators) depending on the previous Treatment ((clinical phase I). At the end of these 2 treatment weeks and a subsequent training phase which up to 3 weeks, treatment with the Silencia PD cycler for 2 further weeks (clinical phase II).
Study: NCT04702516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ozempic
Description: 2 mg prefilled pen for subcutaneous injection, 0.25 mg for two weeks then 0.5 mg for two weeks and then 1 mg for another 48 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 mg prefilled pen for subcutaneous injection, 0.25 mg for two weeks then 0.5 mg for two weeks and then 1 mg for another 48 weeks.
Study: NCT06325917

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: what's app ongoing support
Description: daily educational messages and reminders sent through WhatsApp. The educational material related to diabetes self-management behaviors (AADE7 Self-Care Behaviors, diabetes and genetics, and endocrinology center, also the Ministry of Health in Jordan diabetes.~individual bidirectional communication between the participants and the investigator, which will allow participants to seek advice and get free-of-charge feedback and consultation.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: usual care
Description: monthly visit and follow-up at the diabetes education clinic by a diabetes nurse specialist providing DSMES
Study: NCT06173011

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QL2107
Description: intravenous infusion 35 min (±5min, minimum infusion 30min), D1 (Day 1, single dose)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Keytruda®(china)
Description: intravenous infusion 35 min (±5min, minimum infusion 30min), D1 (Day 1, single dose)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Keytruda®(US)
Description: intravenous infusion 35 min (±5min, minimum infusion 30min), D1 (Day 1, single dose)
Study: NCT04853966

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity counseling
Description: Physical activity counseling will be performed using physical activity behavior steps of the transtheoretical model.