TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05799066

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Swinging Light test
Description: The swinging light or pen light test with manual pupil measurements is the standard of care test for RAPD. This test consists of a light being shone in one eye for 3 to 4 seconds then shown in the other eye for 3 to 4 seconds, repeating 2 to 3 times. Pupils are measured manually immediately after the light test. Measurements are recorded in patient's medical record.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Swinging Light test
Description: The swinging light or pen light test with manual pupil measurements is the standard of care test for RAPD. This test consists of a light being shone in one eye for 3 to 4 seconds then shown in the other eye for 3 to 4 seconds, repeating 2 to 3 times. Pupils are measured manually immediately after the light test. Measurements are recorded in patient's medical record.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Virtual Reality Head-Mounted Display (VR HMD)
Description: A light is shone from within the VR HMD, pupillary measurements are taken and recorded by the machine learning (ML) algorithm.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Virtual Reality Head-Mounted Display (VR HMD)
Description: A light is shone from within the VR HMD, pupillary measurements are taken and recorded by the machine learning (ML) algorithm.
Study: NCT04549571

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Media Intervention
Description: Utilize the CDB

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Media Intervention
Description: Utilize the CDB

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Utilize usual care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT06351774

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical therapy
Description: Physical therapy for the treatment of chronic low back pain, as directed by a licensed Physical Therapist. The Healthy Minds Innovations (HMI) program is an app-based learning platform developed through the University of Wisconsin-Madison Center for Healthy Minds. The HMI app includes foundational meditation practices and short podcast-style lessons based on the science of wellbeing to cultivate mindfulness, positive relationships, and insight into the nature of the self.
Study: NCT06263400

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: psychoeducation and follow-up study
Description: In the study, we hypothesized that the caregiver psychoeducation program (consisting of six sessions over a 3-week period) would improve depressive symptoms in depressed patients, increase recovery levels, reduce the caregiver's burden, and reduce emotional expression levels in the family.
Study: NCT05984979

Intervention type: OTHER
Intervention: Standardized meal
Description: The participants will receive a standardized meal for breakfast

Intervention type: OTHER
Intervention: Standardized meal
Description: The participants will receive a standardized meal for breakfast

Intervention type: OTHER
Intervention: Standardized meal
Description: The participants will receive a standardized meal for breakfast
Study: NCT04345601

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stromal Cells
Description: Patients will be given the cell product by intravenous injection (into the vein through an IV line). Dose:1 x 10\^8 MSCs.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stromal Cells
Description: Patients will be given the cell product by intravenous injection (into the vein through an IV line). Dose:1 x 10\^8 MSCs.

Intervention type: OTHER
Group type: OTHER
Intervention: Supportive Care
Description: Patients will receive supportive care per their treating physician
Study: NCT04563546

Intervention type: OTHER
Group type: OTHER
Intervention: Quality Improvement
Description: A quality improvement intervention including reminders, care protocols, and text messages to improve care of myocardial infarction in the KCMC ED
Study: NCT06233331

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dose Level 1 ACU-D1 ointment
Description: ACU-D1 is a topical therapeutic agent that has pentaerythritol tetrakis (3-(3,5-di-tert-butyl-4-hydroxyphenyl) propionate) (PTTC) as its major active ingredient. PTTC is a novel proteasome inhibitor that has antiangiogenic and anti-inflammatory activities that reduce pro-inflammatory cytokines. ACU-D1 ointment contains a range of 2.5% to 10% weight by volume of PTTC.~Level 1 will consist of 2.5% ACU-D1 ointment, used twice daily for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dose Level 2 ACU-D1 ointment
Description: Level 2 will consist of 5% ACU-D1 ointment, used twice daily for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dose Level 3 ACU-D1 ointment
Description: Level 3 will consist of 10% ACU-D1 ointment, used twice daily for 4 weeks.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vulvar/ Perianal Biopsy
Description: 3 vulvar or perianal biopsies are to be performed at the screening as well as at the end of the study (week 4).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vulvar/ Perianal Biopsy
Description: 3 vulvar or perianal biopsies are to be performed at the screening as well as at the end of the study (week 4).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vulvar/ Perianal Biopsy
Description: 3 vulvar or perianal biopsies are to be performed at the screening as well as at the end of the study (week 4).
Study: NCT05705648

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: medium chain triglyceride oil
Description: Medium chain triglyceride oil

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Safflower oil
Description: Safflower oil
Study: NCT05485987

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vatiquinone
Description: Vatiquinone will be administered per dose and schedule specified in the arm.
Study: NCT05199090

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MBL949
Description: subcutaneous injections administered for 14 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MBL949
Description: subcutaneous injections administered for 14 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MBL949
Description: subcutaneous injections administered for 14 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MBL949
Description: subcutaneous injections administered for 14 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MBL949
Description: subcutaneous injections administered for 14 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo Comparator to MLB949
Study: NCT06080256

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alirocumab
Description: alirocumab (75 mg every 2 weeks)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Atorvastatin 20-40mg
Study: NCT04705168

Intervention type: DIAGNOSTIC_TEST
Intervention: Nevisense electrical impedance spectroscopy
Description: Each participants will undergo Nevisense electrical impedance spectroscopy in order to characterize the electrical impedance spectroscopy scores of nevi in patients with ≥ 100 nevi on the entire cutaneous surface and at least three large acquired nevi (LAN) \> 5 mm in diameter
Study: NCT06080256

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin
Description: Atorvastatin 20-40mg
Study: NCT06058676

Intervention type: PROCEDURE
Intervention: carotid artery stenting
Description: The procedures will be performed for patients with general or local anesthesia. Implantation of stents at the site of carotid artery stenosis for the treatment of carotid severe stenosis. A suitable balloon will be selected based on the internal carotid arterial（ICA）diameter, as shown on the digital subtraction angiography（DSA）image. The use of a balloon for predilatation or postdilatation depends on the degree of stenosis. The type of stent will be selected according to several factors, such as the length and configuration of the lesion, vascular morphology, vessel diameter, plaque characteristics, stent characteristics, and surgeon experience.

Intervention type: PROCEDURE
Intervention: carotid artery stenting
Description: The procedures will be performed for patients with general or local anesthesia. Implantation of stents at the site of carotid artery stenosis for the treatment of carotid severe stenosis. A suitable balloon will be selected based on the internal carotid arterial（ICA）diameter, as shown on the digital subtraction angiography（DSA）image. The use of a balloon for predilatation or postdilatation depends on the degree of stenosis. The type of stent will be selected according to several factors, such as the length and configuration of the lesion, vascular morphology, vessel diameter, plaque characteristics, stent characteristics, and surgeon experience.
Study: NCT05529420

Intervention type: OTHER
Intervention: measurement of the depth of neuromuscular blockade
Description: time of TOF 1 measurement (= clinical effect, stimulation of the ulnar nerve - adductor pollicis muscle tension) will be documented in the CRF and if there is no need to add further doses of the muscle relaxant, TOF 2, TOF 3, TOF 4, and TOF-R ≥ 0,9 (= time to full recovery from the effect of the non-depolarizing muscle relaxant) will also be registered.
Study: NCT04797468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX23
Description: administered IV.
Study: NCT06442176

Intervention type: DIAGNOSTIC_TEST
Intervention: OCT
Description: Enhanced depth imaging optical coherence tomography (EDI-OCT) using the Heidelberg Spectralis HRA + OCT (Heidelberg Engineering, Inc., Franklin, MA, USA)

Intervention type: DIAGNOSTIC_TEST
Intervention: OCT
Description: Enhanced depth imaging optical coherence tomography (EDI-OCT) using the Heidelberg Spectralis HRA + OCT (Heidelberg Engineering, Inc., Franklin, MA, USA)
Study: NCT05060081

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercise program group
Description: Pilates exercise program group will do a warm-up for 10 minutes and then perform five exercises includes standing footwork, hundreds with knee straight, articulating bridge, rolling like a ball, plank for 25 minutes. For first three weeks, each player will do 8 repetitions × 3 sets of exercises and for next three weeks, each player will do 15 repetitions × 3 sets of exercises. There will be cool-down for 10 minutes after exercises. Total program will be of 45 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional plank exercise program group
Description: Traditional plank exercise program group will do a warm-up for 10 minutes and then perform five exercises includes prone bridge, side bridge, supine bridge on exercise ball, prone bridge on exercise ball, superman on exercise ball. For first three weeks, each player will do 8 repetitions × 3 sets of exercises and for next three weeks, each player will do 15 repetitions × 3 sets of exercises. There will be cool-down for 10 minutes after exercises. Total program will be of 45 minutes.
Study: NCT06388356

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational intervention - Yksityisyyttä ensihoitoon / Informational privacy for preospital emergency care
Description: Educational intervention is a self-study, online course on Koulumaali platform about patient's informational privacy (IP) in prehospital emergency care (PEC).~It comprises three separate educational modules approximately 30 min. long: module I) the meaning and significance of IP and its protection, module II) legislation regarding IP and its protection in healthcare and module III) breaches of IPand its protection in PEC.~Each module contains theoretical sections as well as case-exercises and tests.~Participants will have four weeks time to execute the entire course independently. Participants can execute the modules according to their own schedule. The modules need to be completed in certain order by following the numerical order from first to third. Only one of the modules is open at a time and the second module activates after the previous modules has been completed. Already completed modules become inactive.
Study: NCT05246943

Intervention type: DIAGNOSTIC_TEST
Intervention: D-dimer and lower limb venous duplex
Description: D-dimer blood test- The D-dimer assay detects the presence of fibrin degradation products, which can indicate the breakdown of a fibrin clot Lower Limb Venous Duplex- Using an ultrasound to visually look for a clot
Study: NCT06017310

Intervention type: DIAGNOSTIC_TEST
Intervention: Evaluate the performance of IFN I/III
Description: Evaluate the response in diagnosing non-respiratory viral infection.
Study: NCT05637567

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetylsalicylic acid
Description: 100 mg per os once daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo pill per os once daily
Study: NCT05393895

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CSF-1
Description: One drop bilaterally twice daily for approximately 6 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: One drop bilaterally twice daily for approximately 6 weeks
Study: NCT04776538

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Stem cells
Description: Each participant will be double-blindly randomized to receive either adipose-derived allogeneic stem cells or placebo consisting of CryoStor10 (BiolifeSolutions), the freeze media for ASCs containing 10% Dimethyl sulfoxide (DMSO).

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Each participant will be double-blindly randomized to receive either adipose-derived allogeneic stem cells or placebo consisting of CryoStor10 (BiolifeSolutions), the freeze media for ASCs containing 10% Dimethyl sulfoxide (DMSO).
Study: NCT04835623

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine 0.09% Ophthalmic Solution
Description: one drop each eye twice daily
Study: NCT06299670

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thalidomide
Description: Patients will get only Thalidomide
Study: NCT05786885

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microneedling will be done with application of topical vitamin C paste for depigmentation
Description: A Dermapen device will be used to microneedle the gingival tissue (model M8) with 24 microneedles arranged in rows, which is adjusted with 1.5 mm depth at the 6th mode speed of 700 cycles/min.~It will be used in intermittent motion on the affected area for 30-40 seconds / tooth.~Once bleeding points are observed on all areas of the pigmented gingiva, it will be irrigated using saline solution and dried using sterile gauze.~Topical vitamin C powder (1000 mg/ml) will be mixed with saline, and the resultant slurry mix will then be applied to the gingiva for 10 minutes.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin C injection
Description: 1-1.5 ml Vitamin C will be injected into the gingiva, using an insulin syringe, once weekly, for 3 weeks.~All the injection procedures will be performed by the same operator. The treated area will be left without dressing in both groups.
Study: NCT06299670

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxy Urea
Description: Patients will get only Hydroxyurea

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combinations
Description: Combination Of Thalidomide \& Hydroxyurea
Study: NCT05260138

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gentle Body message
Description: The intervention group received gentle body massage twice/day and position change from supine to lateral every two hours under the phototherapy for three consecutive days in addition to routine NICU care.
Study: NCT06461390

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Norepinephrine
Description: NE Group (Fluid loading with early norepinephrine administration group) NE Group will receive ringer lactate bolus 20 ml/kg along with norepinephrine infusion at 0.1 mcg/kg/minute until MAP\&gt;5 percentile. Additional fluid boluses of 10-20 ml/kg will be administered (up to a total of 60 ml/kg) until shock resolution or signs of fluid overload are observed, with or without continued norepinephrine infusion according to the treatment group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ringer's Lactate
Description: Fluid Group will receive ringer lactate bolus 20 ml/ kg only. Additional fluid boluses of 10-20 ml/kg will be administered (up to a total of 60 ml/kg) until shock resolution or signs of fluid overload are observed
Study: NCT05260138

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine NICU Care
Description: received the conventional NICU care of infants undergoing phototherapy. Phototherapy was given by single Blue LEDs emitting light in a narrow spectrum (450-470 nm). Initially, phototherapy lamps were checked and adjusted at the height of 30 cm from the neonates who were kept naked in the incubator/crib except for the reproductive organs with shielded eyes. The neonates were positioned supine under the phototherapy. The treatment was given continuously, except while feeding and nursing for 30 minutes every 3 hours. The neonates' skin was cleaned with warm water without applying any sorts of ointments oils or creams. They were also observed for signs of dehydration.
Study: NCT05468580

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endoscopic Coeliac Artery Release (eCAR)
Description: Endoscopic Coeliac Artery Release (eCAR); The Median Arcuate Ligament will be cleaved via an endoscopic retroperitoneal approach using a 4 trocar technique described in detail by van Petersen (12). To rule out learning curves and procedural variation all the procedures will be performed by two experienced eCAR surgeons in the MST-Dutch Expert Centre of Gastrointestinal Ischemia. All procedures will be videotaped. Both eCAR surgeons will not be involved in the follow up procedures.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham Operation
Description: The sham operation consists of making 4 incisions up to the fascia similar to endoscopic AC release (eCAR). After 60 to 75 minutes of general anesthesia, in accordance with the average operating time of eCAR, the sham operation is ended. This study design allows for patient and observer blinding and for the sham group the eCAR approach is still feasible if the CARoSO outcome support this without applying additional scar tissue.
Study: NCT04970823

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The somatosensory interactive game for preschool children
Description: The somatosensory interactive game, an independent nursing intervention, promotes pain relief for preschool children.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A VR (virtual reality) game for school-age children
Description: A VR (virtual reality) game environment promotes pain relief for school-age children.
Study: NCT05556083

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sildenafil 50 mg Oral Tablet and Dapoxitine 3mg Oral tablet
Description: Single blind placebo randomized controlled trial

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet and Dapoxitine 3mg Oral tablet
Description: Single blind placebo randomized controlled trial