TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06389682

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-NYM005 injection
Description: he radiation dose is about 2-7 mCi for a single patient.Using a syringe to withdraw 68Ga-NYM005 injection, the dose will be administered via an intravenous injection and the injection time will be about 45-60 seconds.
Study: NCT04250766

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Echo-guided uterine biopsy
Description: Echo-guided uterine biopsy will be performed by a specialized radiologist by transvaginal and exclusive transuterine approach. 4 to 5 samples will be made.~Local anesthesia will be performed. A pain assessment will be performed during the biopsy (visual or verbal scale).
Study: NCT06044714

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual Standardized Stress Acupuncture (MSSA)
Description: Participants in the experimental group will receive 4 weekly sessions of MSSA, which consists of 8 acupuncture points: bilateral auricular (ear) shen men, GV- 20, GV-24.5 (Yin Tang), bilateral LI-4, and bilateral LR-3. Needles are left in situ for 30 minutes per session.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction (MBSR)
Description: Participants will receive four sessions of MBSR group psychotherapy (no more than 10 participants per group session) via Microsoft Teams. The first session will be 90 minutes followed by three 60-minute weekly sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness-Based Stress Reduction (MBSR)
Description: Participants will receive four sessions of MBSR group psychotherapy (no more than 10 participants per group session) via Microsoft Teams. The first session will be 90 minutes followed by three 60-minute weekly sessions.
Study: NCT05950360

Intervention type: DEVICE
Intervention: Electromagnetic tracking system, surface electromyography
Description: arm elevation in the scapular plane, overhead reaching to the target 15° backward to the frontal plane, pull-up with overhead reaching forward and backward.

Intervention type: DEVICE
Intervention: Electromagnetic tracking system, surface electromyography
Description: arm elevation in the scapular plane, overhead reaching to the target 15° backward to the frontal plane, pull-up with overhead reaching forward and backward.
Study: NCT06127810

Intervention type: DEVICE
Intervention: CE MRI on 0.064T Scanner
Description: Pt will undergo contrast enhanced images using Gadopiclenol on Hyperfine MRI
Study: NCT05774522

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Measurement of pharyngeal critical airway closing pressure
Description: The Pcrit will be measured on an automatic controlled device specially designed by the engineers of the inserm neophen team capable of varying the pressures from +4 to -20 centimeters of water, by a nasal mask whose pressures are connected to a pneumotachograph. The measurements will be performed in supine position.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acoustic pharyngometry
Description: Acoustic pharyngometry is an non-invasive technique consisting of the propagation of an acoustic wave from the lips to the larynx providing information on the lengths, cross-sectional areas and volumes of the air spaces.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Upper airway ultrasound
Description: Airway ultrasound is a non-invasive imaging allowing visualization and measurements of the tongue base and retrovascular fatty infiltration. Its main interest remains the evaluation of the tongue base which is clinically difficult.
Study: NCT05687448

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5 MG Oral Tablet
Description: Patients treated with apixaban 5 mg twice daily (BID)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: warfarin with an objective of INR target of 2.5 (range: 2.0-3.0)
Description: Patients treated with warfarin with an objective of INR target of 2.5 (range: 2.0-3.0)
Study: NCT06127810

Intervention type: DEVICE
Intervention: CE MRI on 0.064T Scanner
Description: Pt will undergo contrast enhanced images using Gadopiclenol on Hyperfine MRI

Intervention type: DRUG
Intervention: Gadopiclenol
Description: Subjects will receive Gadopiclenol instead of standard of care contrast

Intervention type: DRUG
Intervention: Gadopiclenol
Description: Subjects will receive Gadopiclenol instead of standard of care contrast
Study: NCT06349304

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Freeze-dried table grape powder
Description: Consumption of grape powder as part of daily diet
Study: NCT04735172

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: specific MRI Acquisition (NMR spectroscopy) at 7T
Description: The MRI protocol will be performed at 7T on a Siemens NMR imaging system (Magnetom Terra, Siemens Healthcare, Erlangen, Germany), the radio frequency emission and signal reception will be done through a head quadrature resonator (64-channel phase-array coil). To avoid motion-related artifacts, the patient will be seated in a supine position, with the arms along the body and the head immobilized using a suitable head restraint. The MR protocol will take place in two phases:~* Acquisition of 3D multi-slice T1 and T2-weighted morphological images to identify areas of interest;~* Acquisition of 1D RMN spectra in the right and left putamen and STN. Spectra will be acquired in volumes of interest of 15mmx15mmx15mm using a localized spectroscopy sequence with and without suppression of the water signal. Main parameters are: TR (repetition time)=3000ms; TE (echo time)=20 ms; number of repetitions=128; scan time 6min).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: specific MRI Acquisition (NMR spectroscopy) at 7T
Description: The MRI protocol will be performed at 7T on a Siemens NMR imaging system (Magnetom Terra, Siemens Healthcare, Erlangen, Germany), the radio frequency emission and signal reception will be done through a head quadrature resonator (64-channel phase-array coil). To avoid motion-related artifacts, the patient will be seated in a supine position, with the arms along the body and the head immobilized using a suitable head restraint. The MR protocol will take place in two phases:~* Acquisition of 3D multi-slice T1 and T2-weighted morphological images to identify areas of interest;~* Acquisition of 1D RMN spectra in the right and left putamen and STN. Spectra will be acquired in volumes of interest of 15mmx15mmx15mm using a localized spectroscopy sequence with and without suppression of the water signal. Main parameters are: TR (repetition time)=3000ms; TE (echo time)=20 ms; number of repetitions=128; scan time 6min).
Study: NCT06349304

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo grape powder
Description: Consumption of placebo grape powder as part of daily diet
Study: NCT05434598

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ChromoSeq
Description: Novel, streamlined whole genome sequencing approach
Study: NCT05788250

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subacromial spacer implantation
Description: A biodegradable balloon implanted arthroscopically between the acromion and humeral head with tenotomy of long head of biceps.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rotator cuff repair
Description: Rotator cuff repair with tenotomy of long head of biceps.
Study: NCT06212869

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation
Description: tDCS group will give active tDCS with the prescribed medications for 20 minute. The intervention will conduct 3 consecutive days in a week.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial direct current stimulation
Description: Sham tDCS group will give sham tDCS with the prescribed medications for 20 minute. The intervention will conduct 3 consecutive days in a week.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Green light
Description: Green light group will give green light exposure with the prescribed medications for 1-2 hour. The intervention will conduct 5 days in a week.
Study: NCT06390813

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Otago Exercise Training
Description: A total of 18 sessions of Otago Training were conducted 3 days a week for 6 weeks, each session lasting 60 minutes in total, including 5 minutes of warm-up and cool-down periods.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Square Stepping Exercise Training
Description: A total of 18 sessions of SSE were performed 3 days a week for 6 weeks, each session lasting 40 minutes.
Study: NCT05270044

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Encorafenib and Binimetinib
Description: Encorafenib 450 mg (6 × 75 mg capsules) once daily (QD) and binimetinib 45 mg (3 x 15 mg tablets) twice daily (BID) orally for a maximum of 12 months.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo to match Encorafenib ; Placebo to match Binimetinib
Description: Encorafenib (6 × 75 mg placebo capsules) QD and binimetinib (3 × 15 mg placebo tablets) BID placebos orally for a maximum of 12 months.
Study: NCT05712538

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARCT-032
Description: ARCT-032 is messenger RNA (mRNA) coding for cystic fibrosis transmembrane conductance regulator (CFTR) protein, formulated in a lipid nanoparticle (LNP).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARCT-032
Description: ARCT-032 is messenger RNA (mRNA) coding for cystic fibrosis transmembrane conductance regulator (CFTR) protein, formulated in a lipid nanoparticle (LNP).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Normal saline
Study: NCT06295471

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DFG Laser
Description: Laser treatment to the upper thigh

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CO2 Laser
Description: Laser treatment to the upper thigh

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optical coherence tomography (OCT)
Description: Angiographic OCT imaging at areas of interest
Study: NCT05883748

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DISC-1459
Description: DISC-1459 dose level 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DISC-1459
Description: DISC-1459 dose level 2
Study: NCT05215236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Opiate Sparing
Description: Subjects will receive non-opiate medications for pain control

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Opiate Based
Description: Subjects will receive opiate based medications for pain control
Study: NCT05337137

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Relatlimab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Specified dose on specified days
Study: NCT05799235

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Telerehabilitation TAR program using a mobile application
Description: Participants in this study arm will use a mobile application which allows participants to perform their home exercises with real-time feedback given, allowing for proper execution of exercises, on top of standard care.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard rehabilitation sessions
Description: Participants in this control group will attend standard in person rehabilitation sessions with home exercise program given as per standard care.
Study: NCT04688333

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet-Based Intervention - Complete iConquerFear program
Description: Online adaptation of a highly effective face-to-face treatment for fear of recurrence.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study: NCT04331158

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry cupping therapy
Description: Dry cupping therapy application on the patient's skin

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Dry cupping therapy
Description: Dry cupping therapy application on the patient's skin
Study: NCT04914637

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Cervical interlaminar epidural steroid injection
Description: Fluoroscopy-guided cervical interlaminar epidural steroid injection will be administered to patients with chronic neck pain due to cervical disc herniation. The injection area is cleaned 3 times with an antiseptic solution and covered with a sterile cloth. Local anesthesia with 2 cc 3% prilocaine will be applied to the skin and subcutaneous tissues in the area of interest. Under fluoroscopy guidance, the needle is advanced into the C7-T1 intervertebral disc level. With the help of the loss of resistance technique, it is understood that the needle is in the epidural space, and second control is provided by administering contrast material. After the confirmation of needle place is done, a mixture of 12 mg dexamethasone, 1 cc 2% lidocaine, 1 cc saline is injected. The patient is taken to the rest room after the procedure and followed up for any complications.
Study: NCT05644847

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole Body Vibration Training
Description: WBV training will be performed on a commercial vibrating platform (Healthmate HM01-08VF Gym Fitness Equipment Step Vibration Machine, China), which produces vertical sinusoidal vibrations. Participants in the dynamic WBV group will be provided with dynamic exercises along with WBV training. The vibration speed level will be progressed from level 5 to level 10 during the course of the treatment sessions

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Core Stability Training
Description: Core stability exercises will include pelvic bridge, straight leg bridge, modified kneeling with elbow support and leg lifts and squats, with 60 seconds rest interval between each activity. All these core exercises will be performed on a stable surface and will be progressed in difficulty by increasing the no. of repetitions and no. of sets on a weekly basis. Every session will be preceded by 5 minutes of warm-up and end with 5 minutes of cool-down exercises.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Core Stability Training
Description: Core stability exercises will include pelvic bridge, straight leg bridge, modified kneeling with elbow support and leg lifts and squats, with 60 seconds rest interval between each activity. All these core exercises will be performed on a stable surface and will be progressed in difficulty by increasing the no. of repetitions and no. of sets on a weekly basis. Every session will be preceded by 5 minutes of warm-up and end with 5 minutes of cool-down exercises.
Study: NCT04804501

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blue Light Glasses
Description: Participants will be randomized into an experimental group (blue light glasses) or a control group (no glasses). Participants will perform a computer reading task while either wearing, or not wearing the glasses.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Computer Reading Task
Description: Participants will read on a computer until concussion symptoms increase by a score of 3 or more (reading task termination criteria). One or more points will be assigned for each increase in symptom severity, and one point will be assigned for each new symptom that appears.

Intervention type: OTHER
Group type: OTHER
Intervention: Computer Reading Task
Description: Participants will read on a computer until concussion symptoms increase by a score of 3 or more (reading task termination criteria). One or more points will be assigned for each increase in symptom severity, and one point will be assigned for each new symptom that appears.
Study: NCT05536505

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Adjuvant treatment for MRD positivity
Description: The MRD positive group would receive icotinib as adjuvant treatment. When the peripheral blood MRD turned negative, the subjects entered the drug withdrawal observation period. When the MRD turned positive again, the subjects resumed icotinib treatment. If EGFR T790M mutation was found, researchers would resume medication and choose osimertinib therapy.
Study: NCT04807478

Intervention type: DRUG
Intervention: Omegaven® (fish oil triglycerides) Injectable Emulsion
Description: Dose, frequency and duration is a decision of the Investigator
Study: NCT05337137

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Specified dose on specified days
Study: NCT05815199

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-cigarette (EC)
Description: Fixed dose. Participants are to use the EC as replacement for smoking combustible cigarettes. Participants will vape the EC.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine Replacement Therapy (NRT)
Description: Includes nicotine patches and lozenges. NRT use recommendations will follow the guidelines of the product, e.g. one patch per day.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Harm-Reduction Counseling
Description: At baseline, after randomization, participants will receive their first telehealth session (20\~25 minutes) from a counselor trained in motivational interviewing, harm reduction, and smoking cessation. Up to five additional sessions will be delivered, 15\~20 minutes each.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Harm-Reduction Counseling
Description: At baseline, after randomization, participants will receive their first telehealth session (20\~25 minutes) from a counselor trained in motivational interviewing, harm reduction, and smoking cessation. Up to five additional sessions will be delivered, 15\~20 minutes each.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ecological Momentary Intervention (EMI) Text Messaging
Description: EMI can be defined as delivering tailored interventions via electronic messages (i.e., regular text messages) that include personalized feedback based on real-time assessment responses and other contextual factors. EMI will take place throughout the intervention period.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Ecological Momentary Intervention (EMI) Text Messaging
Description: EMI can be defined as delivering tailored interventions via electronic messages (i.e., regular text messages) that include personalized feedback based on real-time assessment responses and other contextual factors. EMI will take place throughout the intervention period.
Study: NCT04988828

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Whole body vibration
Description: vertical vibration platform with the frequency of 30Hz, amplitude of 4mm. The intervention will last for 5 weeks, twice /week.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Whole body vibration
Description: vertical vibration platform with the frequency of 30Hz, amplitude of 4mm. The intervention will last for 5 weeks, twice /week.
Study: NCT04914637

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cervical interlaminar epidural steroid injection
Description: Fluoroscopy-guided cervical interlaminar epidural steroid injection will be administered to patients with chronic neck pain due to cervical disc herniation. The injection area is cleaned 3 times with an antiseptic solution and covered with a sterile cloth. Local anesthesia with 2 cc 3% prilocaine will be applied to the skin and subcutaneous tissues in the area of interest. Under fluoroscopy guidance, the needle is advanced into the C7-T1 intervertebral disc level. With the help of the loss of resistance technique, it is understood that the needle is in the epidural space, and second control is provided by administering contrast material. After the confirmation of needle place is done, a mixture of 12 mg dexamethasone, 1 cc 2% lidocaine, 1 cc saline is injected. The patient is taken to the rest room after the procedure and followed up for any complications.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Cervical interlaminar epidural steroid injection
Description: Fluoroscopy-guided cervical interlaminar epidural steroid injection will be administered to patients with chronic neck pain due to cervical disc herniation. The injection area is cleaned 3 times with an antiseptic solution and covered with a sterile cloth. Local anesthesia with 2 cc 3% prilocaine will be applied to the skin and subcutaneous tissues in the area of interest. Under fluoroscopy guidance, the needle is advanced into the C7-T1 intervertebral disc level. With the help of the loss of resistance technique, it is understood that the needle is in the epidural space, and second control is provided by administering contrast material. After the confirmation of needle place is done, a mixture of 12 mg dexamethasone, 1 cc 2% lidocaine, 1 cc saline is injected. The patient is taken to the rest room after the procedure and followed up for any complications.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dry needling
Description: Dry needling will be applied to the active trigger points for the patients in this group. After cleaning the area of interest with an antiseptic solution, dry needling will be applied with the fast-in/fast-out technique for the active trigger point. During needle maneuvers, local contractions (local twitch response-LTR) are obtained and rapid needle movements are continued until the contractions end. Afterwards, the needle is removed and compression is applied to ensure hemostasis in the relevant area.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham dry needling
Description: Although the method of intervention is like dry needling, the only difference is that the blunt end of the needle is used and it does not penetrate the skin.
Study: NCT06667453

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PGN-EDODM1
Description: Administered by intravenous (IV) infusion

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered by intravenous (IV) infusion
Study: NCT06667284

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Roux en y procedure
Description: subtotal gastrectomy en bloc with Roux-en-Y reconstruction, using TA 90 and GIA staplers. The length of the biliopancreatic limb was 50 cm, while the alimentary limb was 80 cm

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Omega brown procedure
Description: Gastrojejunal anastomosis with jejunojejunal anastomosis