TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06673095

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies
Study: NCT05803902

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental drug 9MW1911
Description: Experimental drug administered with IV infusion
Study: NCT05314556

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group psychotherapy
Description: Additional group psychotherapy for patients with narcolepsy type 1 with standard medication
Study: NCT05312437

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interruptive Alert, CDS
Description: Experimental: CDS Intervention Adult patients in the highest predicted risk tier (\>=2% predicted risk) at the time visit registration (aka check-in).~The Intervention would then be described as:~Physicians review a Best Practice Advisory describing the patient's risk and choose from the following options:~1. Document face-to-face suicide risk screening with the Columbia Suicide Severity Rating Scale (CDS complete once the CSSRS is complete)~2. Agree to screen using an alternative method chosen at the clinician's discretion (CDS complete)~3. Disagree with alert and provide a rationale for disagreement (CDS complete)~4. Indicate suicide risk face-to-face screening has already occurred (CDS complete)~5. Dismiss the alert. The alert will be available in Epic Storyboard persistently until acted on further. The Storyboard functionality after dismissal is identical to the Passive Prompt, CDS intervention (below)
Study: NCT05312437

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Passive Prompt, CDS
Description: Adult patients in the highest predicted risk tier (\>=2% predicted risk, based on our research study, DOI: 10.1001/jamanetworkopen.2021.1428) at the time of visit registration (aka check-in) will be randomized to either the Interruptive Alert or Passive Prompt CDS intervention arms.~In the Passive Prompt arm, the physician who next opens the patients' charts after check-in (e.g., Chart Review) will see a Storyboard icon for Elevated Suicide Risk on the left side of the screen. Hovering over this icon will bring up a window with the BPA information in a view identical to the Interruptive Alert arm. Clicking on the window will bring up the BPA with full functionality as in the Interruptive Alert arm.
Study: NCT06345937

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioural Experimental: guidelines-based physical activity
Description: Through a combination of exercise trainer-led in-person and virtual sessions, as well as counselling for independent aerobic exercise, participants will be guided to achieve 150 weekly minutes of moderate-intensity aerobic activity and twice weekly whole-body muscle strengthening.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioural Experimental: guidelines-based physical activity and healthy eating
Description: Behavioural Experimental: guidelines-based physical activity:~Through a combination of exercise trainer-led in-person and virtual sessions, as well as counselling for independent aerobic exercise, participants will be guided to achieve 150 weekly minutes of moderate-intensity aerobic activity and twice weekly whole-body muscle strengthening.~Behavioural Experimental: guidelines-based healthy eating:~One-on-one phone/virtual counselling from a registered dietitian to change dietary habits to be in line with Canada's Food Guide.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Behavioural: Stretching exercise
Description: Twice weekly virtual instructor-led whole-body stretching.
Study: NCT05803902

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental drug 9MW1911
Description: Experimental drug administered with IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental drug 9MW1911
Description: Experimental drug administered with IV infusion
Study: NCT06386081

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Citrus pectin with low DE
Description: Dietary intervention with citrus pectin with low DE. Participants will orally take the supplement twice a day, after dissolving it in 100ml of water, for 2 months.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Apple pectin with high DE
Description: Dietary intervention with apple pectin with high DE. Participants will orally take the supplement twice a day, after dissolving it in 100ml of water, for 2 months.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will orally take the placebo (maltodextrin) twice a day, after dissolving it in 100ml of water, for 2 months. Maltodextrin is highly digestible and in small amounts will have limited impact on gut microbiome.
Study: NCT05803902

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo administered with IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo administered with IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo administered with IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo administered with IV infusion
Study: NCT04864158

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise-group
Description: The exercise-group will attend a 12-week exercise program with one weekly physiotherapist-supervised session supplemented with two weekly sessions of home-based exercises. Utilisation of a predefined training protocol describing procedures and content of each session secure uniformity and standardisation of the intervention. The exercise program consists of two warm-up exercises and five exercises that target shoulder range of motion and muscle strength. Furthermore, a link to a video, informing about glenohumeral osteoarthritis, the role of exercise and exercise related pain, will be sent to all patients in the exercise-group. The physiotherapists delivering the exercise intervention are not otherwise related to the trial.
Study: NCT06395961

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: high ankle block
Description: The block position is in the middle and lower third of the calf, about 15cm above the inner or outer ankles. 0.375% ropivacaine is used for the block and the total dose is 35ml. The ultrasound probe is placed vertical to the longitudinal axis of the body. On the lateral of tibia and fibula, 5ml of local anesthetic was injected to block the superficial peroneal nerve and 10ml for the deep peroneal nerve. On the posterior of the calf, 10ml of local anesthetic was injected to block the tibial nerve and 5ml for the sural nerve. On the inner side of the calf, 5ml of local anesthetic was injected to block the saphenous nerve. The water separation technique is used and 2ml of physiological saline is injected before blocking to clarify the position of the needle tip and avoid nerve damage. 20 minutes after, the effect was measured using acupuncture by visual analogue scale (VAS) score. If the VAS score is less than 3, the block is considered successful and surgery is immediately performed.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: general anesthesia
Description: intravenous injection of midazolam 0.03-0.05 mg/kg, etomidate 0.15-0.20 mg/kg, cisatracurium 0.15-0.20 mg/kg, and sufentanil 0.3-0.5 μg/kg. Intraoperative anesthesia maintenance using intravenous infusion of remifentanil 0.1-0.3 μg/kg·min, propofol 4-6 mg/kg·h, maintain bispectral index (BIS) value of 40-60, maintain intraoperative blood pressure and heart rate fluctuations within ± 20% of the baseline value, intermittently inject cisatracurium intravenously as needed. After the surgery, the patient was transferred to post-anaesthesia care unit (PACU). After regaining consciousness and regaining autonomous breathing, the tracheal catheter was removed and transferred to the ward when the indications for transfer were met.
Study: NCT04722991

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Runcaciguat (BAY1101042)
Description: Oral dose of runcaciguat

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral dose of matching placebo
Study: NCT06293118

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ischemic conditioning group
Description: The ischemic conditioning protocol will consist of a period of 12 weeks (24 sessions) with a frequency of 2 weekly sessions lasting between 15 and 20 minutes each. Therapy will be performed bilaterally on the upper limbs. The ischemic conditioning group will perform 4 times, 8 cycles with 30 seconds of ischemia (80 - 200 mmHg) with 5 seconds of reperfusion in each cycle. Ischemia cycles are controlled by a device (KAATSU C3 - KAATSU GLOBAL / USA) with customized ischemia programs, partially restricting blood flow through special pressure cuffs that are internally valved, providing greater comfort and safety for these patients who typically have stiffness in the affected limb and localized muscle pain. In the first cycle, participants will be subjected to pressures of 80 to 150 mmHg. In the 3 subsequent cycles, pressures from 130 to 200 mmHg will be applied.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham group
Description: Participants in the control group (Sham) will perform 4 cycles of 5 minutes of ischemia (30 mmHg) with 4 subsequent cycles of reperfusion (rest) bilaterally in the arms with a sphygmomanometer
Study: NCT06540651

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: use of Luminettes ® with active light emission
Description: Spectrum of 400 \< X \< 750 nm assumed active

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: use of Luminettes ® with a light emission presumed to have no therapeutic effect
Description: Modification of spectrum parameters for wavelengths covered, with light emission in a spectrum of 560 \< X \< 650 nm assumed to have no therapeutic effect
Study: NCT05546723

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous CAR-T cell therapy expressing the BAFF-ligand.
Description: LMY-920
Study: NCT06359314

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ALDER
Description: The ALDER skills are delivered over approximately 5 weeks. A week consists of learning at least one skill and then applying that skill(s) in daily home practice throughout the week. Skill lessons and daily home practice exercises are housed on the ALDER website. Participants have the option to share their home practice responses with fellow participants by posting them to the discussion board, where they can like and comment on each other's posts.
Study: NCT06477068

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Mobile medical reminder application
Description: Experimental group: Patients undergoing ovarian stimulation in the Infertility Department at Hung Vuong Hospital are prescribed and instructed to inject medication according to the current procedure of the department, in addition to being supported through the telemedicine medication reminder app on smartphones.~Control group: Patients undergoing ovarian stimulation in the Infertility Department at Hung Vuong Hospital are prescribed and instructed to inject medication according to the current procedure of the department.
Study: NCT06226428

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bed cyclo-ergonometry
Description: The MotoMed Letto 2 device will be used, with a progressive pattern, starting at 5 minutes and lasting up to 30 minutes. It will be performed once a day, during weekdays (Monday to Friday) until discharge from the intensive care unit, and at a modified Borg intensity of 2-3 (Light).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bed mobility activities (turning, pelvic elevation and sitting), standing, transfers and walking.
Description: Bed mobility activities (turning, pelvic elevation and sitting), standing, transfers and walking.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bed mobility activities (turning, pelvic elevation and sitting), standing, transfers and walking.
Description: Bed mobility activities (turning, pelvic elevation and sitting), standing, transfers and walking.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive upper and lower limb strength training
Description: Performing isometric exercises, strengthening with multi-resistance elastic bands or multi-weight dumbbells.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Progressive upper and lower limb strength training
Description: Performing isometric exercises, strengthening with multi-resistance elastic bands or multi-weight dumbbells.
Study: NCT05655104

Intervention type: OTHER
Intervention: Couplet Care
Description: In the Couplet Care model, the parents are provided access to the infant stabilisation room and encouragement for early skin-to-skin contact, mothers receive their postpartum care in the same NICU room with the infant, and fathers/partners also have a bed in the same NICU room.
Study: NCT06524505

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: deep Transcranial Magnetic Stimulation (dTMS) -active
Description: with the H1-coil device included 20-min sessions of 18 Hz (2-s trains separated by 20-s inter-train intervals, 55 trains totaling 1980 pulses/session).
Study: NCT05166798

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive control training
Description: The five intervention groups will receive either 1, 5, 10, 15 or 20 training sessions with the Adaptive Paced Auditory Serial Addition Task (aPASAT).
Study: NCT06524505

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: deep Transcranial Magnetic Stimulation (dTMS) -sham
Description: The sham stimulation was performed using the same procedures, with the sham coil.
Study: NCT05295303

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Remote integrated post-MI management system
Description: The home-based remote integrated post-MI management system comprises (1) a patch-based long-term Holter monitoring system HC3A250 (BISA Technologies (Hong Kong) Limited, Hong Kong SAR, China), (2) a handheld single-lead electrocardiogram (ECG) recorder (Comfit Healthcare Devices Limited, Hong Kong SAR, China), (3) a blood pressure monitor, (4) a patient-facing smartphone application specially designed for the study, and (5) a web-based clinical management system for clinicians

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Remote integrated post-MI management system
Description: The home-based remote integrated post-MI management system comprises (1) a patch-based long-term Holter monitoring system HC3A250 (BISA Technologies (Hong Kong) Limited, Hong Kong SAR, China), (2) a handheld single-lead electrocardiogram (ECG) recorder (Comfit Healthcare Devices Limited, Hong Kong SAR, China), (3) a blood pressure monitor, (4) a patient-facing smartphone application specially designed for the study, and (5) a web-based clinical management system for clinicians
Study: NCT06121518

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: D064 and D702, QD
Description: Experimental Group Subjects assigned to this group are treated with D064, D702

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: D064 and Placebo of D702, QD
Description: Comparator Group Subjects assigned to this group are treated with D064, placebo of D702

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo of D064 and D702, QD
Description: Comparator Group Subjects assigned to this group are treated with D702, placebo of D064
Study: NCT04246203

Intervention type: OTHER
Intervention: Liquid Biopsy
Description: 17-20 ml of blood will be collected prior of surgery and within 14 days before start of adjuvant chemotherapy.

Intervention type: OTHER
Intervention: Liquid Biopsy
Description: 17-20 ml of blood will be collected prior of surgery and within 14 days before start of adjuvant chemotherapy.
Study: NCT06039228

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and commitment therapy
Description: Four sessions of group acceptance and commitment therapy, with each session lasting for 1.5 hours.
Study: NCT05155592

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: reduction or discontinuation of Adalimumab
Description: For patients with non-infectious uveitis whose inflammation stabilizes after treated with Adalimumab, extended dosing intervals to once a month, during which inflammatory status is monitored. If there was no recurrence within 6 months, Adalimumab was discontinued, and whether inflammation recurred after withdrawal was observed.
Study: NCT05027737

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Early Ileostomy Closure
Description: Following a negative leak test (CT scan with rectally-administered water-soluble contrast on post-operative day 7, 8 or 9), patients will undergo standardized reversal of their diverting loop ileostomy (stapled side-side functional end-to end anastomosis, purse-string closure of the ileostomy wound, and no use of epidural analgesia) between post-operative days 10-14.
Study: NCT06529900

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: oral mastication training
Description: Through specific exercises and techniques aimed at enhancing masticatory function and overall oral health.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: texture and diet education
Description: Teach the knowledge and techniques of softening food textures.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: texture and diet education
Description: Teach the knowledge and techniques of softening food textures.
Study: NCT06244121

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyridoxine
Description: pyridoxine (Vitamin B6) will be given as an anti oxidant.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be given in control group
Study: NCT06649565

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT06648187

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early motor-cognitive integrative training (e-MCIT)
Description: Early motor-cognitive integrative training (e-MCIT) is an approach where motor and cognitive training are conducted simultaneously. The intervention consists of 30-minute sessions, conducted 4-5 times per week, until discharging from the hospital. Both motor and cognitive training have five stages each, and their progression is independent, meaning that during training, a participant might be in the fourth stage of motor training and the second stage of cognitive training. According to hospital's policy, occupational therapy and speech therapy will be provided in schedule if needed. Motor training is derived from a previous protocol of early mobilization intervention applied to a population with SAH, which based on the ICU Mobility Scale. The activities of cognitive training target areas such as attention, orientation, language ability, memory, calculation, judgment, working memory, executive function, and daily living functions.
Study: NCT06051435

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: lumbar proprioception training
Description: a) Sensorimotor training: Sensorimotor training and reconditioning of proprioceptive senses have recently been found to be helpful in increasing motor performance and coordination, muscle strength, sensorimotor abilities, increasing intermuscular control, and improving one's response to sensory information and muscle tone. Reconditioning of proprioceptive senses and sensorimotor training increases one's muscle adjustment ability, maximizes the sensory input in different parts of the body and aids in improving one's motor adjustment ability (Hwang et al ., 2013).~Position Exercise methods as Hollowing exercise: Participants will be asked to contract the abdominal muscles, raising the center of movement toward the navel in a quadruped position.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hot packs
Description: hot application in the form of hot packs on the lower abdomen and lower back for a total duration of 30 minutes, once per day, during the first two days of menstruation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hot packs
Description: hot application in the form of hot packs on the lower abdomen and lower back for a total duration of 30 minutes, once per day, during the first two days of menstruation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic rocking exercise
Description: Pelvic rocking exercise

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic rocking exercise
Description: Pelvic rocking exercise
Study: NCT05249283

Intervention type: OTHER
Group type: OTHER
Intervention: Questionnaire Measures
Description: Patients will complete the following questionnaires: CDS questionnaire, Niigata PPPD questionnaire, HAD (Hospital Anxiety and Depression) scale and DHI (Dizziness Handicap Inventory)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Measures
Description: Patients will complete the following questionnaires: CDS questionnaire, Niigata PPPD questionnaire, HAD (Hospital Anxiety and Depression) scale and DHI (Dizziness Handicap Inventory)
Study: NCT05100953

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Counseling
Description: Physical activity counseling will be provided under supervision by the researcher physiotherapist via video conference and an individual physical activity program will be organized weekly for two months.
Study: NCT05566873

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: PA Education plus human and planetary health information
Description: One year of continuing person-level physical activity promotion and health-related information delivered primarily by mail, email, and through online scientific video presentations and exploration of freely available citizen science mobile applications

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PA Education plus Our Voice citizen science
Description: One year of continuing person-level physical activity promotion and health-related information delivered primarily by mail and email, plus participatory citizen science activities involving neighborhood audits of the walking environment using a mobile app and remote group discussion and problem-solving around physical activity barriers
Study: NCT06200415

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucosamine Sulfate
Description: Glucosamine sulphate (GLcN) is an N-deacetyl amino sugar derived from the complete hydrolysis of the chitosan with significant anti-inflammatory action.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ginger Oil
Description: Ginger (Zingiber officinale Roscoe) has been found to have biological activities such as antioxidant, anti-inflammatory, antimicrobial, and anticancer activities.
Study: NCT05297084

Intervention type: PROCEDURE
Intervention: non surgical periodontal therapy
Description: Scaling and root planing