TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06044376

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Formula milk with triple Bifidobacterium probiotic strain
Description: Formula milk with triple Bifidobacterium strain containing Bifidobacterium longum BB536 (6.9 x 10\^7 CFU/serving), Bifidobacterium breve M16-V (6.9 x 10\^7 CFU/serving), Bifidobacterium longum subsp. infantis M-63 (6.9 x 10\^7 CFU/serving).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Formula milk
Description: Formula milk without any addition of probiotic strain
Study: NCT06557499

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polyurethane (PU) male condom-Test condom 1
Description: A minimum of 5 condoms (maximum 7 condoms) of each condom type will be provided to couples to be used during vaginal intercourse over a maximum 5-week period (assessment period). Couples will repeat the assessment period for each of the 3 condom types.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polyurethane (PU) male condom-Test condom 2
Description: A minimum of 5 condoms (maximum 7 condoms) of each condom type will be provided to couples to be used during vaginal intercourse over a maximum 5-week period (assessment period). Couples will repeat the assessment period for each of the 3 condom types.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Natural Rubber Latex (NRL) male condom- Control condom
Description: A minimum of 5 condoms (maximum 7 condoms) of each condom type will be provided to couples to be used during vaginal intercourse over a maximum 5-week period (assessment period). Couples will repeat the assessment period for each of the 3 condom types.
Study: NCT04594876

Intervention type: OTHER
Group type: OTHER
Intervention: Flouroscopic guidance cervical epidural versus cervical facet injection
Description: The patients are classified in two groups group P for cervical epidural and group F for facet injection. The skin will be prepared with an antiseptic solution. The midline of the selected interspace will be identified under fluroscopic guidance.

Intervention type: OTHER
Group type: OTHER
Intervention: Flouroscopic guidance cervical epidural versus cervical facet injection
Description: The patients are classified in two groups group P for cervical epidural and group F for facet injection. The skin will be prepared with an antiseptic solution. The midline of the selected interspace will be identified under fluroscopic guidance.
Study: NCT06374082

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: WhatsApp message
Description: Participants in the intervention group will receive 3 WhatsApp messages per week for six weeks after attending the standardized course training Tobacco Dependency Nursing Intervention and Management (NURS8205). These messages are about the core content of the course, including (1) Knowledge Themes: harmfulness of smoking and benefits of quitting, the fundamentals of nicotine addiction, smoking cessation counselling with the 5A model, and pharmacotherapy for smoking cessation; (2) Attitude Themes: nurses' role in smoking cessation and the importance of smoking cessation; and (3) Practice Themes: practical advice on counseling techniques, communication skills by motivational interviewing, local smoking cessation resources for referral.~Participants in the control group will receive 3 WhatsApp messages about generic mental health information per week for six weeks after attending the standardized course training Tobacco Dependency Nursing Intervention and Management (NURS8205).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: WhatsApp message
Description: Participants in the intervention group will receive 3 WhatsApp messages per week for six weeks after attending the standardized course training Tobacco Dependency Nursing Intervention and Management (NURS8205). These messages are about the core content of the course, including (1) Knowledge Themes: harmfulness of smoking and benefits of quitting, the fundamentals of nicotine addiction, smoking cessation counselling with the 5A model, and pharmacotherapy for smoking cessation; (2) Attitude Themes: nurses' role in smoking cessation and the importance of smoking cessation; and (3) Practice Themes: practical advice on counseling techniques, communication skills by motivational interviewing, local smoking cessation resources for referral.~Participants in the control group will receive 3 WhatsApp messages about generic mental health information per week for six weeks after attending the standardized course training Tobacco Dependency Nursing Intervention and Management (NURS8205).
Study: NCT05733494

Intervention type: OTHER
Intervention: Administration of Clinical Assessment of Dysphagia in Neurodegeneration (CADN)
Description: the CADN will be administrated to each patient at the enrolment
Study: NCT05513729

Intervention type: DRUG
Intervention: Canagliflozin
Description: According to the guideline of type 2 diabetes，canagliflozin will be given to 40 patients with type 2 diabetes combined with NAFLD as first-line choice if accompanied with indicators of high risk or established atherosclerotic cardiovascular disease, chronic kidney disease or heart failure, independently of HbA1c level. It can be also given to T2DM combined with NAFLD if their HbA1c above target.

Intervention type: DRUG
Intervention: Pioglitazone
Description: According to the newest guideline of Diabetes，pioglitazone will be given to 40 patients with T2DM combined with NAFLD if their HbA1c above target.
Study: NCT04561271

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: foot reflexology
Description: Patients will receive one session of foot reflexology with a nurse who received a specific formation. The session lasts 15 to 20 minutes, patients seated, half seated or in supine position. A neutral oil will be used. The technique associates specific movements of foot reflexology. The session is accompanied by relaxing music.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: toucher massage
Description: one session of toucher massage with a nurse (this technique is taught during the formation of every nurse in palliative care units). The session lasts 15 to 20 minutes, patients seated, half seated or in supine position. It consists in a simple massage and effleurage, with fluid and progressive movements. Almond oil will be used. The session is accompanied by relaxing music.
Study: NCT05160909

Intervention type: PROCEDURE
Intervention: Beach Chair Position
Description: Patients positioned in beach chair during arthroscopic shoulder stabilization

Intervention type: PROCEDURE
Intervention: Lateral Decubitus Position
Description: Patients positioned in lateral decubitus position during arthroscopic shoulder stabilization
Study: NCT06064305

Intervention type: OTHER
Intervention: No study-specific interventions
Description: Septic AKI patients, post-cardiothoracic AKI patients and non-AKI patients undergoing routine nephrectomy. Due to the observational design of the study, no study-specific interventions are performed. The treatment of the patients is completely guided by the responsible ICU physicians and the respective specialists.

Intervention type: OTHER
Intervention: No study-specific interventions
Description: Septic AKI patients, post-cardiothoracic AKI patients and non-AKI patients undergoing routine nephrectomy. Due to the observational design of the study, no study-specific interventions are performed. The treatment of the patients is completely guided by the responsible ICU physicians and the respective specialists.
Study: NCT05223725

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AdKCNH2-G628S
Description: adenovirus containing the transgene KCNH2-G628S
Study: NCT06064305

Intervention type: OTHER
Intervention: No study-specific interventions
Description: Septic AKI patients, post-cardiothoracic AKI patients and non-AKI patients undergoing routine nephrectomy. Due to the observational design of the study, no study-specific interventions are performed. The treatment of the patients is completely guided by the responsible ICU physicians and the respective specialists.
Study: NCT05015257

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Standard F100
Description: 100 kcal and 3 g protein per 100 ml

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Standard F75 + Plumpynut
Description: Standard F75 with ready to-use therapeutic food (Plumpynut)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alternative F75 with CMV + Plumpynut
Description: Alternative F75 containing CMV with ready to-use therapeutic food (Plumpynut)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alternative F75 without CMV + Plumpynut
Description: Alternative F75 with no CMV with ready to-use therapeutic food (Plumpynut)
Study: NCT05889312

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-FSPG PET/CT in NSCLC
Description: Stage 3 NSCLC with radical curative intent at baseline (pre-treatment) and at 4-8 weeks into treatment.

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-FSPG PET/CT in HNSCC
Description: Stage 3 and 4 HNSCC with radical curative intent at baseline and at 2-4 weeks into treatment.
Study: NCT05223725

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AdKCNH2-G628S
Description: adenovirus containing the transgene KCNH2-G628S

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AdKCNH2-G628S
Description: adenovirus containing the transgene KCNH2-G628S
Study: NCT04876430

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meropenem
Description: Meropenem 2g every 8h for patients with glomerular filtration rate (GFR) equal or higher that 50 mL/min. Dose adjustment is recommended for patients with GFR \< 50mL/min.
Study: NCT05895422

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pyeloplasty
Description: repair of the uPJO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: pyeloplasty
Description: repair of the uPJO
Study: NCT04500626

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxygen
Description: Hyperbaric oxygen therapy delivered in a monoplace or multi-place chamber. Supervised by a hyperbaric oxygen therapy physician and a chamber operator.
Study: NCT05413148

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Subtenon injection of Wharton jelly derived mesenchymal stem cells
Description: Single subtenon's injection for single eye

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Subtenon injection of Wharton jelly derived mesenchymal stem cell exosomes
Description: Single subtenon's injection for single eye

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single Subtenon injection of saline for a single eye
Study: NCT05500430

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Air abrasion sandblasting aluminum oxide particles (Al2O3) AquaCare single (Velopex, Medivance Instruments Ltd., London, UK)
Description: Air abrasion sandblasting aluminum oxide particles (Al2O3) Aqua Care single (London, UK) will be done for the defective area then repairing with bioactive injectable composite, Beautiful Flow Plus X F00 (Shofu, Japan).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Air abrasion sandblasting aluminum oxide particles (Al2O3) AquaCare single (Velopex, Medivance Instruments Ltd., London, UK)
Description: Air abrasion sandblasting aluminum oxide particles (Al2O3) Aqua Care single (London, UK) will be done for the defective area then repairing with bioactive injectable composite, Beautiful Flow Plus X F00 (Shofu, Japan).
Study: NCT05961137

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Incorporation of Rapid Fluid Infusion Device in Prehospital Suspected Sepsis Protocol
Description: Modified protocol specifying intravenous crystalloid infusion Rapid Fluid Infusion Device. The protocol states that for patients meeting the sepsis alert criterion, EMS will provide basic medical care, oxygen, a 12-lead electrocardiogram, attempt placement of an IV catheter and initiate administration of 30mL/kg of fluids.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Prehospital Suspected Sepsis Protocol
Description: Conventional protocol employing intravenous crystalloid infusion via gravity or pressurized-bag. The protocol states that for patients meeting the sepsis alert criterion, EMS will provide basic medical care, oxygen, a 12-lead electrocardiogram, attempt placement of an IV catheter and initiate administration of 30mL/kg of fluids.
Study: NCT05636345

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pain science education
Description: A full day of pain science education
Study: NCT05315089

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality games +conventional exercises
Description: Virtual reality games +conventional exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional exercises
Description: Conventional exercises
Study: NCT05149560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ticagrelor 90mg
Description: All patients will be prescribed ticagrelor as monotherapy
Study: NCT06011018

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror Therapy
Description: Sitting, mirror place at the midline between the legs. Unaffected leg is placed in front of the mirror and perform ankle dorsiflexion exercises.~Duration: 5 seconds, Rest: 5 seconds

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror Therapy + Electrical Stimulation
Description: Same as the mirror therapy protocol. Affected leg: electrical stimulation on tibialis anterior muscle. Frequency: 35 Hz, Pulse width: 250µs, Duration: 5 seconds, Rest: 5 seconds.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror Therapy + Binaural Beat
Description: Same as the mirror therapy protocol. Listen to music (mozart's clarinex concerto in A major K622), with Alpha (8Hz) binaural beat stimulation
Study: NCT05629832

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: mechanical ventilation strategy guided by transpulmonary pressure
Description: Mechanical ventilation parameters adjust guided by transpulmonary pressure monitoring. For pressure assist control or volumn assit control mode; inspiratory pressure or volumn setting needs to maintain Ppeak less than 25 cm H2O; PEEP was set at such a level that expiratory Ptp stayed between 0 and 5 cm H2O.
Study: NCT05796674

Intervention type: DEVICE
Intervention: Clareon UVA IOL
Description: Clareon UVA IOL placed in the capsular bag in the posterior chamber of the eye during cataract surgery to replace the natural crystalline lens. Models CC60WF and CCA0T0 are indicated for the visual correction of aphakia. Models CCW0T3, CCW0T4, CCW0T5, and CCW0T6 are indicated for the visual correction of aphakia and preexisting corneal astigmatism.

Intervention type: DEVICE
Intervention: WaveTec Optiwave Refractive Analysis (ORA) System
Description: Intra-operative system used during refractive cataract surgery to capture wavefront images of the patient's eye for the purpose of optimizing IOL implantation

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Cataract extraction by phacoemulsification, followed by implantation with a Clareon UVA IOL
Study: NCT05840354

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: repetitive transcranial magnetic stimulation
Description: 1-4 weeks after administration of the SJI, participants will attend their first rTMS session. rTMS will be delivered using a biphasic stimulator (DuoMag) and a figure-of-eight coil to the corticomotor representation of the first dorsal interosseous muscle contralateral to the side of worst pain. Recording electrodes will be positioned in a belly-tendon montage over the FDI for electromyography recording. The hotspot and resting motor threshold (rMT) of the FDI will be determined and saved using a Brainsight Neuronavigation system to ensure accurate coil repositioning within and between sessions.~The hotspot and rMT will be confirmed and adjusted if needed at each intervention session. Each rTMS session will consist of 40 trains of 5s delivered at 10Hz, at an intensity of 85% of the resting motor threshold for the FDI muscle and an intertrain interval of 25s (total of 2000 stimulations in a 20-minute session).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham repetitive transcranial magnetic stimulation
Description: Sham intervention will follow same protocol as active rTMS using a sham coil that does not deliver actual magnetic stimulation.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Steroid Joint Injection
Description: The steroid joint injection will be given 1-4 weeks ahead of active rTMS and sham rTMS commencement. A dose of 0.5mL of 40mg/mL triamcinolone and 0.5mL of 2% lidocaine will be given per joint via spinal needle. The treatment team will determine how many joints will be injected based on their standard clinical assessment. Usually, about 2-4 joints are injected depending on a person's pain presentation. Standard practice is to place the needle in the region of the facet joint opening, resulting in a peri- +/- intra-articular infusion of the injectate. This project will utilize standard clinical practice without modification.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Steroid Joint Injection
Description: The steroid joint injection will be given 1-4 weeks ahead of active rTMS and sham rTMS commencement. A dose of 0.5mL of 40mg/mL triamcinolone and 0.5mL of 2% lidocaine will be given per joint via spinal needle. The treatment team will determine how many joints will be injected based on their standard clinical assessment. Usually, about 2-4 joints are injected depending on a person's pain presentation. Standard practice is to place the needle in the region of the facet joint opening, resulting in a peri- +/- intra-articular infusion of the injectate. This project will utilize standard clinical practice without modification.
Study: NCT05839457

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empowerment Pilot
Description: The Empowerment Pilot is a school-based program aimed to raise awareness and change attitudes around SRGBV among students and teachers and promote gender equality. This intervention includes training provided by Teacher Mentors to other teachers in school, learning sessions delivered via safe spaces for student learners, and guidance for engaging parent-teacher committees.
Study: NCT05798390

Intervention type: DRUG
Intervention: Bempedoic acid and/or its fixed dose combination with ezetimibe
Description: This is a non-interventional study. No study medication will be provided as part of this protocol to the patients. Medications will be as prescribed by the treating physician in line with clinical practice.
Study: NCT06312592

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Entrepreneurship School with Gender Lens
Description: The Entrepreneurship School with Gender Lens (ESGL) is an approach that targets gender based violence survivors and women at-risk to help them develop business ideas, access needed support for the prevention of and response to GBV, exploitation and trafficking, and improve participants' overall self-reliance. Participants will go through a general business curriculum, work on business plans and learn gender issues and ways to mitigate GBV risks. Upon training completion, participants are eligible to pitch their business idea to a panel of experts and receive $800 of seed capital. They will also receive follow-up business advisory support for at least six months, focusing on access to markets and finance and building support networks, in order to continue building self-reliance.~The ESGL will also include a mental health and psychosocial support module.
Study: NCT05597618

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training Program to be Developed for Empowering New Graduated Nurses
Description: The training program, which will be prepared based on structural and psychological empowerment theories, will consist of two parts: face-to-face theoretical training and online training.~1. Theoretical Education Part In the theoretical part, empowerment based on structural and psychological empowerment theories, effective communication, problem-solving and decision-making, time management, stress management, and nursing legislation will occur. In addition, the subject related to the institution's promotion (organizational chart, vision, mission, values, etc.) will be included.~2. Online Education Part In the online part; Videos of theoretical education subjects, institutional information, and documents (institutional instructions and procedures, institution vision-mission-values, management chart, etc.), nursing-related legislation (nursing law, nursing regulation), nursing ethical codes and case studies of sample subjects are included.
Study: NCT06663189

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: treatment withdrawal
Description: Patients will STOP their DMT

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Usual DMT continuation
Description: Patients will continue their DMT during the trial as usual : Interferon-β (IFN-β), glatiramer acetate, dimethyl fumarate, teriflunomide or diroximel fumarate

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: Cerebral+spinal cord enhanced MRI (M0) Cerebral enhanced MRI (M6, Relapse early visit) Unenhanced cerebral MRI (M12, M18, M24, Relapse distant visit

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MRI
Description: Cerebral+spinal cord enhanced MRI (M0) Cerebral enhanced MRI (M6, Relapse early visit) Unenhanced cerebral MRI (M12, M18, M24, Relapse distant visit

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Quality of Life questionnaires
Description: EQ-5D5L: EuroQol-5-Dimension 5 levels Burden of Treatment Questionnaire (BTQ self-administered questionnaires) Hospital Anxiety and Depression (HAD) questionnaire
Study: NCT05230849

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dry needling
Description: is a physiotherapy treatment for neurological patients and studies the efficacy of dry needling by studying several pre-treatment and post-treatment variables after the experimental treatment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: convencional treatment
Description: is a physiotherapy treatment for neurological patients
Study: NCT04771676

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oncorine (H101)
Description: A modified human recombinant type 5 adenovirus with genetic modifications.