TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06595576

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis - Placebo Dose (0 mg)
Description: Participants will consume placebo cannabis edibles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis - Low Dose (2 mg)
Description: Participants will consume a low dose (2 mg) of cannabis edibles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis - Medium Dose (10 mg)
Description: Participants will consume a medium dose (10 mg) of cannabis edibles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis - High Dose (20 mg)
Description: Participants will consume a high dose (20 mg) of cannabis edibles.
Study: NCT06587711

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: acupuncture treatment
Description: Patients in experimental group received acupuncture at specific acupoint on the face, patients in control group received sham acupuncture at non-acupoint on the face.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: acupuncture treatment
Description: Patients in experimental group received acupuncture at specific acupoint on the face, patients in control group received sham acupuncture at non-acupoint on the face.
Study: NCT06601088

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neuromuscular Electrical Stimulation
Description: Patients will be instructed to apply the wearable NMES-therapy continuously, both day and night at least 10h/daily.
Study: NCT06592651

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Play Therapy Workshop
Description: 4 session group intervention foucused on psycho-educational knowledge regarding tools for effective emotional coping with stressful events in the context of the Iron Swords war, focusing on building mental resilience in the parent-child dyad through play therapy. Each group consists of 5 parent-child dyads with children aged 3-6 years, who have been evacuated from war zones in the northern and southern regions of the country.
Study: NCT05652010

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: New 2-piece Coupling
Description: Flat or concave baseplate. SenSura Mio Click maxi bag (open, wide outlet) with new 50mm Ø coupling.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SenSura Mio Click
Description: Flat or concave baseplate. SenSura Mio Click maxi bag (open, wide outlet) with 50mm Ø coupling.
Study: NCT06593821

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Occlusal splint
Description: The occlusal splint was fabricated from a 2 mm hard splinting resin material on the plaster model obtained by taking impressions of the patients\&amp;#39; upper jaw.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Occlusal splint
Description: The occlusal splint was fabricated from a 2 mm hard splinting resin material on the plaster model obtained by taking impressions of the patients\&amp;#39; upper jaw.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: preventive advice
Description: Control group given protective advice such as supporting the jaw when yawning, not chewing gum, not opening the mouth for too long and not opening it too wide, and chewing on both sides when eating.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botulinum toxin
Description: A total of 50 U of botulinum toxin, 25 U in each muscle, was injected

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botulinum toxin
Description: A total of 50 U of botulinum toxin, 25 U in each muscle, was injected
Study: NCT06600659

Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study: NCT06369909

Intervention type: PROCEDURE
Intervention: EUS-FNA
Description: For patients with pancreatic masses, EUS-FNA is performed to confirm pathological diagnosis, and pancreatic biopsy samples and duodenal mucosal biopsy samples are collected.

Intervention type: PROCEDURE
Intervention: EUS-FNA
Description: For patients with pancreatic masses, EUS-FNA is performed to confirm pathological diagnosis, and pancreatic biopsy samples and duodenal mucosal biopsy samples are collected.
Study: NCT06600061

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Erector Spinae Plane Block
Description: Patients will receive erector spinae plane block after induction of anesthesia.
Study: NCT06601530

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transversus Thoracic Muscle Plane Block
Description: Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol
Description: Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tramadol
Description: Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes
Study: NCT06527794

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RHYTHM (Remote Hypertension Tracking Help Management)
Description: Home blood pressure telemonitoring with remote medication management by a centralized multidisciplinary team led by a pharmacist; and social support, lifestyle education and connection to community resources to address social needs, provided by a community health worker who is embedded with the centralized team and is tightly connected to community resources and partners

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced usual care (UC)
Description: All participating sites will receive training on appropriate blood pressure measurement and education on guideline-based hypertension therapy. Additionally, participants in usual care will receive a standardized packet with evidence-based hypertension education material and a blood pressure monitor to complete blood pressure measurements at home.
Study: NCT06600230

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education and exercise
Description: Training including information on pelvic floor and dysmenorrhea and exercise practices were given both theoretically and practically by physiotherapists.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self-method like resting or heat
Description: Classical self-methods such as rest and heat application were applied.
Study: NCT06589739

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Headset
Description: A virtual reality headset will be placed on patients\&#39; head before and during chest drain insertion
Study: NCT06591494

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Classic quadruple therapy
Description: Esomeprazole 20 mg BID Bismuth pectin 200 mg BID Amoxicillin 1 g BID Clarithromycin 500 mg BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quadruple therapy with sodium bicarbonate instead of bismuth
Description: Esomeprazole 20 mg BID Sodium bicarbonate 500 mg TID Amoxicillin 1 g BID Clarithromycin 500 mg BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quadruple therapy with sodium bicarbonate instead of clarithromycin
Description: Esomeprazole 20 mg BID Bismuth pectin 200 mg BID Amoxicillin 1 g BID Sodium bicarbonate 500 mg TID
Study: NCT06592716

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Liquid biopsy
Description: The intervention is a liquid biopsy as a blood sample taken in a peripheral vein. The blood samples are analyzed for cell free HPV-DNA.
Study: NCT06592482

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0780
Description: A single A dose of AZD0780 will be administered in the morning on Day 1 under fasted condition. Study intervention will be administered orally with approximately 240 mL of water.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0780
Description: A single A dose of AZD0780 will be administered in the morning on Day 1 under fasted condition. Study intervention will be administered orally with approximately 240 mL of water.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0780
Description: A single A dose of AZD0780 will be administered in the morning on Day 1 under fasted condition. Study intervention will be administered orally with approximately 240 mL of water.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0780
Description: A single A dose of AZD0780 will be administered in the morning on Day 1 under fasted condition. Study intervention will be administered orally with approximately 240 mL of water.
Study: NCT06602661

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fissureless Lobectomy with Reinforced Staple Lines
Description: This intervention involves performing a fissureless lobectomy, a type of lung surgery where the lobes of the lung are removed without dissecting the fissures between them. The procedure utilizes the ECHELON™ 3000 stapler equipped with the ENDOPATH™ stapler line reinforcement. The ENDOPATH™ device uses bioabsorbable buttress material made from Polyglactin and Polydioxanone, designed to enhance the durability and effectiveness of the staple line.~The reinforcement tool is a novel preloaded device with a click and go mechanism, making it easy to load and use during surgery.~The primary objective is to reduce the average duration of hospital length of stay (LOS) directly caused by prolonged air leak (PAL). Secondary objectives include improving intraoperative characteristics (such as duration and amount of blood loss) and postoperative outcomes (such as incidence and duration of PALs, number of chest tube days, and incidence of hospital.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fissureless Lobectomy with Non-Reinforced Staple Lines
Description: This intervention involves performing a fissureless lobectomy, a type of lung surgery where the lobes of the lung are removed without dissecting the fissures between them. The procedure utilizes the ECHELON™ 3000 stapler without any additional reinforcement. This means the staple lines are created using the standard stapler without the use of bioabsorbable buttress materials.~The ECHELON™ 3000 stapler is used to divide the lung parenchyma, pulmonary artery branches, veins, and bronchus without any reinforcement, relying solely on the standard stapling mechanism.
Study: NCT06588088

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Dietary
Description: The diet of these healthy volunteers was such that no calories were consumed after 19.30 in the evening in the first week, and in the second week, 25% of the daily calorie need calculated according to the Harris - Benedict formula was taken, taking into account the nighttime eating syndrome (NES) criteria, after 20.30 in the evening.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietary
Description: The diet of these healthy volunteers was such that no calories were consumed after 19.30 in the evening in the first week, and in the second week, 25% of the daily calorie need calculated according to the Harris - Benedict formula was taken, taking into account the nighttime eating syndrome (NES) criteria, after 20.30 in the evening.
Study: NCT05884645

Intervention type: PROCEDURE
Intervention: Video-directed endotracheal intubation
Description: There will be no intervention in this prospective observational cohort study. Endotracheal intubation is already used to secure the airway by placing an endotracheal tube into the trachea via the oral or nasal route. Indications include the need for airway control during general anaesthesia, mechanical ventilation, resuscitation, and various forms of acute respiratory distress.
Study: NCT06704737

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AR training
Description: Dichoptic augmented reality training with dual-pathway (parvocellular pathway and magnocellular pathway) and interocular push-pull paradigms developed based on neural deficits in adults with unilateral amblyopia

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Patching
Description: Conventional patching therapy.
Study: NCT06704893

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASA injection 40 mg group
Description: Participants will receive intra-articular knee injections under ultrasound guidance with AMNIOGEN® 40mg (HCT Regenerative, New Taipei, Taiwan) diluted in 3.0 mL of sterile normal saline.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASA injection 20 mg group
Description: Participants will receive intra-articular knee injections under ultrasound guidance with AMNIOGEN® 20mg (HCT Regenerative, New Taipei, Taiwan) diluted in 3.0 mL of sterile normal saline.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: HA injection group
Description: Participants will receive intra-articular knee injections under ultrasound guidance with 3 ml of HyLink (SEIKAGAKU CORPORATION, Tokyo, Japan).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline injection group
Description: Participants will receive intra-articular knee injections under ultrasound guidance with 3 ml of sterile normal saline.
Study: NCT06706583

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telematic educational interviews + standard training
Description: Physicians attending at healthcare centers in the experimental arm will receive periodic telematic educational interviews in which an Infectious Diseases consultant will provide practical training on the appropriate use of antibiotics through the review of one of the physician´s randomly chosen antibiotic prescription, according to a structured brief interview.~In addition to this, each of these centres will continue carrying out the already established activities of the Regional ASP (PIRASOA).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard training
Description: Primary Care Health Centers assigned to the control group will receive standard educational activities designated by the current Regional ASP (PIRASOA).
Study: NCT06706050

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Microbiome Therapeutic LP-51
Description: Microbiome therapeutics LP-51 was applied on the individuals suffering from xerosis

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo cream (M23004-03)
Description: placebo cream (M23004-03) was applied on the participants
Study: NCT06704698

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liposomal bupivacaine
Description: Thoracic paravertebral block with liposomal bupivacaine.

Intervention type: DRUG
Group type: OTHER
Intervention: Bupivacaine Hydrochloride
Description: Epidural block with plane bupivacaine.
Study: NCT06705400

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-behavioural
Description: The Bloom Study is implemented in an existing and highly accepted health service delivered by community health nurses. Beyond focusing on food, meals, motor skills and movement, the intervention also target sleep and family sense of security. The intervention commence in pregnancy and continues until the child is 2½ years old.
Study: NCT06706349

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: APA managed by qualified instructor
Description: Each session will be led by a qualified APA professional and will include a mix of aerobic, anaerobic, and 'mind-body' activities like yoga, tailored to participant preferences. Intensity will range from moderate to vigorous, with activities such as walking, cycling, and club-based exercises for at least 20 minutes per session. Participants will be progressively involved in session planning to support continued practice post-study. Heart rate monitoring will be used during exercises like the 6-minute walk test and chair rise test, while a daily activity calendar will help ensure adherence, documenting session dates, durations, subjective intensity, and activity type.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Autonomous APA
Description: A leaflet highlighting the importance of non-sedentary behavior according to WHO recommendations will be provided to them. They will have the opportunity to engage in physical activity autonomously according to their preference.
Study: NCT06706128

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: reflex rolling technique
Description: received reflex rolling technique for 20 min, 5 days a week, for 2 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: lung squeezing technique
Description: lung squeezing technique for 20 min, 5 days a week, for 2 weeks
Study: NCT06705634

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling
Description: A sterile, disposable, solid filament needle (Seirin Corp., Shizuoka, Japan) will be inserted manually into the multifidus of the C5-C6 cervical muscles. Once the needle has been inserted, the needle will be pistoned in an up and down motion within the multifidus muscle at approximately 1Hz for 10 seconds and then left in-situ for 5 minutes.
Study: NCT06240260

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TENS (transcutaneous electrical nerve stimulation) unit
Description: Transcutaneous electrical nerve stimulation (TENS) is a method of pain relief involving the use of a mild electrical current.~A TENS machine is a small, battery-operated device that has leads connected to sticky pads called electrodes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care
Description: Paracervical block only or participant declines analgesia for IUD insertion
Study: NCT06056596

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lamivudine 300 MG
Description: Drug to be taken once daily for three days (two days prior to surgery and on the morning of surgery)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Dose to be taken once daily for three days (two days prior to surgery and on the morning of surgery)
Study: NCT05550779

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mental Exercise
Description: Participant perform a 10-minute mental exercise

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mental Exercise
Description: Participant perform a 10-minute mental exercise
Study: NCT05183178

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prasugrel 10 mg p.o
Description: Prasugrel 10 mg once daily p.o. Patient \>75 years of age or \<60 kg will receive 5 mg prasugrel OD.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ticagrelor 90 mg
Description: Ticagrelor 90 mg twice daily p.o.
Study: NCT06270784

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Extraction
Description: Participants in this group will undergo traditional extraction method. This method involves uncovering the impacted tooth and extracting the tooth with or without dividing it.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Orthodontic Extraction
Description: Participants in this group will undergo orthodontic extraction method. In this method, a two-stage surgical procedure will be performed. In the first operation, the impacted tooth will be uncovered, and then a button will be placed on the tooth. For anchorage purposes, orthodontic mini screws will be placed in the mandibular ramus or zygomaticomaxillary buttress area. Elastics and/or ligature wires fixed to the button will be attached to the mini screw to provide force for the traction of the tooth.~Patients will be called for check-up appointments every two weeks, and the movement of the impacted tooth will be monitored with panoramic x-rays. The second operation will be planned when the tooth moves away from the inferior alveolar nerve. In the second operation, the tooth will be extracted in a similar way to the traditional extraction group.
Study: NCT04935658

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hypnotic relaxation induced by virtual reality (device)
Description: A virtual reality device will be install on the patient 3-5 minutes before the beginning of the oocyte retrieval. The device will be wearing by the patient during the entire intervention and 2 minutes after the end of the ponction.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: local anesthesia
Description: standard anesthesic procedure

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: local anesthesia
Description: standard anesthesic procedure
Study: NCT05036096

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CBBCT Imaging
Description: Both breasts will be scanned by CBBCT. Only one breast will be scanned if the patient had mastectomy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CBBCT Imaging
Description: Both breasts will be scanned by CBBCT. Only one breast will be scanned if the patient had mastectomy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital Mammography
Description: Both breasts will take digital mammography standard views (CC, MLO) Only one breast will take digital mammography standard views if the patient had mastectomy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital Mammography
Description: Both breasts will take digital mammography standard views (CC, MLO) Only one breast will take digital mammography standard views if the patient had mastectomy.
Study: NCT06456567

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Telitacicept
Description: Subcutaneous injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subcutaneous injection
Study: NCT06605664

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Hyperpolarized 13C pyruvate MRI
Description: The subject enrolled in this trial will receive DNP-MRI scanning for two times through hyperpolarized \[1-13C\]pyruvate injection (\~250 mM, 0.43 mL/Kg) before and 2-5 weeks after radiotherapy.
Study: NCT06605495

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: fumigation with Chinese medicine
Description: Eye fumigation with the Eyesight Eye Therapy,10 minutes once daily for 6 weeks.
Study: NCT05491616

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: In this SANO-3 study, patients will receive Nivolumab at 480mg Q4W starting 10-14 weeks after nCRT (i.e., when cCR has been established) until disease progression or unacceptable toxicity, for a maximum duration of 1 year.
Study: NCT05048979

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Telehealth-facilitated supervised exercise program. Veterans with PAD will be enrolled in a 12-week, 3 day a week, aerobic training program in a self-selected location.
Study: NCT04621981

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Bicarbonate Ringer's Solution
Description: This group was treated with Sodium Bicarbonate Ringer's Solution.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Normal Saline
Description: This group was treated with normal saline.