TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06625645

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Modified triple antibiotic paste (TAP) mixed with chlorehexidine
Description: M-TAP with CHX 2%

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Modified Triple Antibiotic Paste mixed with saline
Description: M-TAP mixed with saline

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Calcium Hydroxide mixed with chlorohexidine Intracanal medication
Description: calcium hydroxide powder mixed with CHX 2% solution as intracanal medication

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: calcium hydroxide mixed with saline as intracanal medication
Description: calcium hydroxide mixed with saline as intracanal medication for necrotic primary molars
Study: NCT06127966

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector Spinae Plane Block
Description: The patient assumes a prone position, and the appropriate lumbar vertebral level is identified using ultrasound, based on the preoperative markings of the surgical incision site. After disinfection, the ultrasound probe is placed in the parasagittal direction, 3 centimeters lateral to the midline, to identify the corresponding lumbar transverse process and the overlying erector spinae and latissimus dorsi muscles. Using an in-plane technique, the needle is advanced, and when the needle tip contacts the bony transverse process and there is no blood or gas upon aspiration, 2-3 mL of isotonic saline solution is injected to confirm the correct needle position. Local anesthetic is then injected between the erector spinae muscle and the transverse process. The spread of the local anesthetic in the deep fascial plane within the erector spinae muscle can be visualized using ultrasound.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: 0.9% physiological saline (20ml) injection under ultrasound-guided Erector Spinae Plane Block (ESPB).
Description: The patient is placed in a prone position, and the appropriate lumbar vertebral level is determined using ultrasound based on the preoperative markings of the surgical incision site. After disinfection, the ultrasound probe is positioned in the parasagittal direction, 3 centimeters lateral to the midline, to identify the corresponding lumbar transverse process, erector spinae, and latissimus dorsi muscles above it. Using an in-plane technique, the needle is advanced, and when the needle tip contacts the bony transverse process, and there is no blood or gas upon aspiration, 2-3 milliliters of isotonic saline solution are injected to confirm the correct needle position. Subsequently, 20 milliliters of 0.9% physiological saline is injected between the erector spinae muscle and the transverse process. The diffusion of the physiological saline in the deep fascial plane within the erector spinae muscle can be visualized using ultrasound.
Study: NCT06170502

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Using the mobile application and applying the survey
Description: In the study, The Form for Determining the Educational Needs of Parents Administering Medicines at Home, Introductory Information Form, Parental Drug Preparation Information Evaluation Form, Parent Evaluation Form in Suspension Drug Administration, Capsule Drug Application Parent Evaluation Form, developed by the researchers in line with the literature, Tablet Pharmaceutical Application Parent Evaluation Form, Mobile Application Usability Questionnaire, AkilMobil Expert Opinion Evaluation Form and STAI State Anxiety Inventory developed by Spielberger et al. will be used.
Study: NCT05564650

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT06426134

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: (R)-3-hydroxybutyl (R)-3-hydroxybutyrate)
Description: 1x50g ingestion of pure dGK

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Maltodextrin, Fructose, Pectin, Sodium alginate, Sodium chloride
Description: Isocaloric carbohydrate control (active control)
Study: NCT06244030

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stabilization group
Description: The athletes in the training group will be applied 15-20 repetitions of core stabilization exercise program 3 days a week for 6 weeks by the researcher.
Study: NCT06459037

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Saliva obtaining
Description: The patient was asked to sit upright and tilt his/her head forward to collect saliva samples. İn this way, unstimulated saliva was allowed to accumulate in the floor of the mouth. The accumulated saliva was collected in a sterile container. It was then transferred to a propylene tube. The tubes were centrifuged and the clear part at the top of the tube was taken with a sterile syringe and transferred to a different propylene tube with 0.5 ml in each tube. Tubes were stored at -80ºC until the day of analysis.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Saliva obtaining
Description: The patient was asked to sit upright and tilt his/her head forward to collect saliva samples. İn this way, unstimulated saliva was allowed to accumulate in the floor of the mouth. The accumulated saliva was collected in a sterile container. It was then transferred to a propylene tube. The tubes were centrifuged and the clear part at the top of the tube was taken with a sterile syringe and transferred to a different propylene tube with 0.5 ml in each tube. Tubes were stored at -80ºC until the day of analysis.
Study: NCT05861102

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Jaktinib
Description: Participants will receive 100 mg Jaktinib orally twice daily for 16 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive matching placebo orally twice daily for 16 weeks
Study: NCT04655144

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone delivered to the uterine arterial bed, prior to embolization.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline delivered to the uterine arterial bed, prior to embolization.
Study: NCT04742166

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Reconstruction
Description: Lateral gastrojejunal Terminolateral gastrojejunal

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Reconstruction
Description: Lateral gastrojejunal Terminolateral gastrojejunal
Study: NCT06533852

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fecal Microbiome Transplantation (FMT)
Description: Two doses:~First dose: 24 capsules of FMT at baseline. Second dose: 24 capsules of FMT at 3 months.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: FMT Placebo
Description: Two doses:~First dose: 24 capsules of FMT placebo at baseline. Second dose: 24 capsules of FMT placebo at 3 months.
Study: NCT06027632

Intervention type: OTHER
Group type: OTHER
Intervention: Cognitive exercises with supervision
Description: The experimental group will receive a 12-week intervention consisting of three 20-minute online cognitive stimulation sessions per week along with a weekly 30-minute centralized online remote supervision session with a neuropsychologist. Patient will also have access to the PRESCO program of the HAPPYNeuron-Pro software, which is designed to train up to 12 different cognitive domains, including attention, memory, executive functions and processing speed

Intervention type: OTHER
Group type: OTHER
Intervention: Cognitive exercises without supervision
Description: Patient will have access to the program named PRESCO of the HAPPYNeuron-Pro software, which is designed to train up to 12 different cognitive domains, including attention, memory, executive functions and processing speed
Study: NCT04731025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gentamicin, Cefazolin and Vancomycin
Description: The antibiotic solution will contain 1000 mg vancomycin, 80 mg gentamicin and 1000 mg cefazolin in a 500 mL isotonic saline solution. The solution will be used to wash the dissected implant pocket and the implant prior to insertion in the implant pocket.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 500 mL of sterile isotonic (9%) saline. The solution will be used to wash the dissected implant pocket and the implant prior to insertion in the implant pocket.
Study: NCT03083431

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Oral propranolol (1.6 mg propranolol-hydrochloride/kg/d in 4 divided dosages)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral solution containing the same excipients as propranolol solution
Study: NCT05850390

Intervention type: OTHER
Intervention: Respiratory-Responsive Vocal Biomarker application
Description: A smartphone app that allows participants to receive a respiratory-responsive vocal biomarker (RRVB) score by recording a 6-second held ahh vowel elicitation. The applications returns the RRVB score which has previously been validated to correspond to the likelihood that the user's voice is similar to those of people diagnosed with asthma. This study will examine if the RRVB scores correlate with respiratory function and symptoms in asthma patients.
Study: NCT05940896

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab vedotin
Description: Disitamab Vedotin intravenously combined with radiotherapy (concurrent)
Study: NCT06228872

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cognitive Computerized Training (CCT) plus Anodic transcranial Direct Current Stimulation (tDCS)
Description: Computerized Cognitive Training (15 min) + Anodal tDCS over DLPFC (20 min) daily for 1 month

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Cognitive Computerized Training (CCT) plus sham transcranial Direct Current Stimulation (tDCS)
Description: Computerized Cognitive Training (15 min) + Sham tDCS over DLPFC (20 min) daily for 1 month
Study: NCT05273775

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS5091 Tablets
Description: HRS5091 Tablets once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam Maleate Tablets
Description: Midazolam Maleate Tablets single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Warfarin Sodium Tablets
Description: Warfarin Sodium Tablets single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole Enteric Capsules
Description: Omeprazole Enteric Capsules single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin K1 Tablets
Description: Vitamin K1 Tablets once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Digoxin Tablets
Description: Digoxin Tablets single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin Calcium Tablets
Description: Rosuvastatin Calcium Tablets single dose
Study: NCT05323188

Intervention type: OTHER
Intervention: Tryptase dosage
Description: Collection of biological waste from a blood test for complete blood count (CBC) of care. Centrifugation to recover the plasma, then dosage of the tryptase.
Study: NCT04769505

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: digital mindfulness-based intervention (MBI)
Description: The digital MBI consists of four auditory guided mindfulness exercises lasting between 10 and 15 minutes. The four exercises are a body scan and three sitting meditations (awareness of the heartbeat, awareness of the body, awareness of sounds). The exercises can be conducted via a software (https://www.movisens.com/de/produkte/movisensxs/) on participants' smartphones. Participants will be familiarized with the concept of mindfulness and the intervention in a single face-to-face introductory session. Additionally, participants will receive a manual, containing all relevant information. Participants will be instructed to practice at least once daily over the course of eight weeks. We recommended to come up with a fixed time point for the mindfulness practice to facilitate a routine. They can choose individually between the exercises. After the intervention period, participants received the exercises as audio files and could continue practicing.
Study: NCT05324280

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture treatment will be performed according to a defined protocol, and includes body and ear acupuncture.
Study: NCT05280899

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Weight-bearing As Tolerated
Description: The WBAT group will be instructed to bear weight as tolerated immediately following their surgical procedure. The rehabilitation protocols provided will be identical beyond the initial weightbearing recommendations. Following the initial protection phase (three weeks), whereby the two weightbearing interventions will be provided, patients will progress through standardized phases including mobility and neuromuscular retraining, muscle balance and strengthening, functional training, and finally, advanced training for return to work and sport.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Partial Weight-bearing
Description: The PWB group will be instructed to bear weight to a maximum of 20 lbs of bodyweight on the operative limb for the initial three weeks (termed toe touch), with graduated return to full weightbearing thereafter.
Study: NCT05878665

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
Description: The investigators are aiming for a 10% reduction in iodine dosage at 10 kVp reduction in CT radiation. Routine iodine dosing is 0.521 g I/kg at 120 kVp. Therefore, at 90 kVp, a 30% reduction in iodine dosing is expected, which is 0.365 g I/kg. At 100 kVp, the iodine dosage is reduced to 0.417 g I/kg, which is a 20% reduction. The kVp value is automatically selected by the CT device according to the body habitus, which is a clinical routine.
Study: NCT05062252

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mirror Medacta Shoulder System
Description: Anatomic total shoulder arthroplasty system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medacta Shoulder System
Description: Anatomic total shoulder arthroplasty system - standard configuration
Study: NCT06040502

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The DICE Approach
Description: Systematic guidance for care partners through assessment and management of the behavioral and psychological symptoms of dementia
Study: NCT06091618

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: new technique of ejaculatory preserving laser prostatectomy
Description: laser will be employed to preform vaporization. The ejaculatory preserving procedure will be done in the following steps:~Setting a mark cut 1 cm proximal of the verumontanum as orientation. Complete resection of the middle lobe to the abovementioned mark. Vaporization of lateral lobes to the capsule and the ventral side to the level of the verumontanum with avoidance of paracollicular digging.~Circular resection of the internal bladder neck. Apical resection utilizing the colliculus seminalis as a distal resection border and maintaining a 1cm safety area for preservation of ejaculation.~Total removal of prostate cuts and final check to confirm that there are no obstructive components.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional technique of laser vaporization of the prostate
Description: conventional laser vaporization of the prostate
Study: NCT06302088

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SAINTS program
Description: A brief descriptive name used to refer to the intervention(s) studied in each arm of the clinical study. A non-proprietary name of the intervention must be used, if available. If a non-proprietary name is not available, a brief descriptive name or identifier must be used.
Study: NCT06143059

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethanol
Description: Sterile, 95% ethanol will be administered through IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethanol
Description: Sterile, 95% ethanol will be administered through IV infusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline is administered as the placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline is administered as the placebo
Study: NCT05602922

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Liu-Zi-Jue Exercise
Description: Combined with the actual situation of stroke patients, this Liu-Zi-Jue Exercise adopts the sitting position.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Basic treatment +Swallowing rehabilitation training
Description: Basic treatment +Swallowing rehabilitation training
Study: NCT05295758

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PAL2
Description: Community health worked based intervention to mitigate psychosocial and life circumstance barriers to optimize health promotion coupled with high blood pressure and lifestyle disease state education~Other Names:~Pragmatic personalized, adaptable approach to lifestyle and life circumstance
Study: NCT03869749

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning to BREATHE Plus
Description: Activities include psycho-education about stress and emotion regulation, and practices of body scanning, non-aerobic yoga, and meditation, which are designed to cultivate and provide opportunities to practice present-focused, non-judgmental attention.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health and wellness
Description: The Health Education Wellness Program (modeled after Hey Durham) (Bravender, 2005) will provide didactic information on substance use, nutrition/body image, stress management, exercise, and signs of depression/suicide.
Study: NCT05901584

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: Cadonilimab (10mg/kg, administered on the first day of each cycle, Q3W, until there is no clinical benefit)+platinum-based chemotherapy or Cadonilimab (10mg/kg, administered on the first day of each cycle, Q3W, until there is no clinical benefit), Q3W, 4cycles), every 3 weeks (21 days) is a treatment cycle.
Study: NCT05225571

Intervention type: OTHER
Intervention: no intervention
Description: there is no any intervention in this study. it is an observational and cross-sectional study.
Study: NCT05655468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dronedarone
Description: oral administration fed conditions

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: strictly identical in appearance with dronedarone,oral administration fed conditions
Study: NCT04958902

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
Description: RESTORE (www.restoreonline.ca) includes eight e-modules anticipated to be approximately 30-40 minutes each in length and intended to be completed over 4-8 weeks. The modules address cognitive and behavioural factors posited to cause and maintain psychological distress related to the COVID-19 pandemic. These include cognitions about the cause and meaning of stressors related to the pandemic, including self-blame, other blame and hindsight bias, as well as problematic beliefs related to safety, trust, and control. The modules also address the importance of: (1) expressing emotions that are natural to the events of the pandemic (e.g., sadness in the face of loss), (2) working through, rather than avoiding, thoughts, feelings and grief related to the pandemic, and (3) utilizing social supports. The modules consist of written materials, brief videos, and practice assignments delivered through the platform. RESTORE includes guidance via direct messaging and/or brief telephone calls.
Study: NCT05910060

Intervention type: DIAGNOSTIC_TEST
Intervention: OTTAWA ANKLE RULES
Description: count the ottawa score and do an x-ray if the score is greater than or equal to 1
Study: NCT04939753

Intervention type: DRUG
Intervention: Sevoflurane
Description: Sevoflurane administration to sedate the patient
Study: NCT06247332

Intervention type: OTHER
Intervention: Review of available clinical data sources related to use cases
Description: There will be a review of available clinical data sources related to use cases. In addition, this information will be complemented by a cohort of anonymized retrospective data of 100 cases obtained from the clinical information resulting from the assistance to COVID-19 patients managed by the Primary Care Health District of Sevilla Norte and the Infectious Diseases Department of the Virgen Macarena University Hospital
Study: NCT05171868

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eye Movement Desensitization and Reprocessing (EMDR)
Description: Each participant in the intervention group will receive 8 individual, weekly EMDR sessions over 8 weeks. Each session will take approximately 60-90 minutes. The sessions will be delivered at a place convenient to the participant. Trained EMDR therapists will deliver the intervention.
Study: NCT06211387

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Exercise Training
Description: Resistance Exercise Training for knee

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resistance Exercise Training
Description: Resistance Exercise Training for knee

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Joint Mobilization
Description: Tibiofemoral and Patellofemoral Joint Mobilization
Study: NCT04758234

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3549492
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3549492
Description: Administered orally.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally.