TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06337708

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smart Walk
Description: Smart Walk is a culturally tailored, Social Cognitive Theory-based multi-component smartphone delivered physical activity (PA) promotion intervention that delivered through the Smart Walk application, virtual physical activity coaching, and text messages. The Smart Walk smartphone application includes four key features: 1) personal profile pages, 2) culturally relevant multi-media physical activity promotion modules, 3) discussion boards, and 4) physical activity self-monitoring/tracking feature that integrates with Fitbit activity monitors for participants to track their daily, weekly, and monthly activity. Virtual physical activity coaches will actively engage and facilitate group-based dialogue among participants on the app discussion boards and provide individualized, one-on-one PA coaching via telephone or commercially available app-based video teleconferencing software (i.e., FaceTime, Zoom, Google hangouts).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Fitbit
Description: This intervention group will receive a Fitbit activity monitor and be encouraged to use the commercially available device to increase physical activity.
Study: NCT05889078

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A 4-week walking intervention
Description: Participants will walk along a predetermined route 3 times per week for a period of 4 weeks, answering a pre- and post-intervention questionnaire as well as weekly questionnaires measuring their affect and other variables related to wellbeing. Participants will be randomly assigned to one of two conditions (nature vs urban setting), determining whether the predetermined route they will walk is in a nature or urban setting.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A 4-week walking intervention
Description: Participants will walk along a predetermined route 3 times per week for a period of 4 weeks, answering a pre- and post-intervention questionnaire as well as weekly questionnaires measuring their affect and other variables related to wellbeing. Participants will be randomly assigned to one of two conditions (nature vs urban setting), determining whether the predetermined route they will walk is in a nature or urban setting.
Study: NCT06448039

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fibroblast Growth Factor 2
Description: Randomized double-blinded placebo-controlled treatment of 20 patients with chronic (\>6 month), dry tympanic membrane perforations will be repaired with a gelatin sponge soaked with FGF2 or saline in a 3:1 ratio, then covered with a fibrin glue. Up to four applications will be administered at 3 week intervals or until complete healing is observed.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline control
Description: Randomized double-blinded placebo-controlled treatment of patients with chronic (\>6 month), dry tympanic membrane perforations will be repaired with a gelatin sponge soaked with saline, then covered with a fibrin glue. Up to four applications will be administered at 3 week intervals or until complete healing is observed.
Study: NCT03959982

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HHHFA Device
Description: Participants will be instructed to use the HHHFA for at least 4 hours during their sleep but will be allowed to use it as long as they want during sleep.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Spirometry
Description: Pre and post spirometry using albuterol.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Spirometry
Description: Pre and post spirometry using albuterol.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: 6-minute walk
Description: 6-minute walk

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 6-minute walk
Description: 6-minute walk

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: CT scan
Description: CT scan

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CT scan
Description: CT scan

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Medical Research Council dyspnea scale (MRC)
Description: MRC questionnaire

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical Research Council dyspnea scale (MRC)
Description: MRC questionnaire

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: St. George's Respiratory Questionnaire (SGRQ)
Description: SGRQ questionnaire

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: St. George's Respiratory Questionnaire (SGRQ)
Description: SGRQ questionnaire

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: COPD Assessment Test (CAT)
Description: CAT questionnaire

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: COPD Assessment Test (CAT)
Description: CAT questionnaire

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pittsburgh Sleep Quality Index (PSQI)
Description: PSQI questionnaire

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pittsburgh Sleep Quality Index (PSQI)
Description: PSQI questionnaire

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CASA-Q
Description: CASA-Q questionnaire

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CASA-Q
Description: CASA-Q questionnaire

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spirehealth Tag Device
Description: Subjects will wear the Spirehealth Tag Device to measure heart rate, respiratory rate, sleep time, physical activity (movement), and calories burned with activity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spirehealth Tag Device
Description: Subjects will wear the Spirehealth Tag Device to measure heart rate, respiratory rate, sleep time, physical activity (movement), and calories burned with activity.
Study: NCT06246812

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Deans' Fit Family Challenge
Description: An annual 8-week physical activity and weight loss competition between VCOM-Auburn, AU College of Nursing, and AU Harrison School of Pharmacy

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Deans' Fit Family Challenge
Description: An annual 8-week physical activity and weight loss competition between VCOM-Auburn, AU College of Nursing, and AU Harrison School of Pharmacy

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text message
Description: Three text messages per week to promote and motive physical activity
Study: NCT05553392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: StrataXRT
Description: StrataXRT is a full contact flexible wound dressing for the prevention and treatment of radiation dermatitis. StrataXRT is a semi-occlusive, self-drying and transparent gel.~When used as directed StrataXRT dries to form a protective layer that is gas permeable and waterproof which hydrates and protects compromised skin areas and superficial wounds from chemical and microbial invasion. StrataXRT may be directly applied to radiation dermatitis, compromised skin surfaces, superficial wounds and first and second degree burns.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aquaphor
Description: Aquaphor is a brand of over-the-counter (OTC) skin care ointments manufactured by Beiersdorf Inc.~Aquaphor contains 41 percent petrolatum (or petroleum jelly), the active ingredient, temporarily protects minor cuts, scrapes, and burns; protects and helps relieve chapped or cracked skin and lips; helps protect from the drying effects of wind and cold weather.
Study: NCT06094647

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Altitudes USA
Description: Experimental participants will be onboarded to the digital platform, including the different spaces and how to use the site. The site includes educational and therapeutic content that is tailored to each individual and their current needs and experiences, including psychoeducation, supporting their loved one, self-care, social support, and so on. Further, the platform includes a moderated social media function, where users and family peer workers can post text, images, videos, and comments to connect and share their experiences. The site is monitored by graduated students and trained clinicians.
Study: NCT04720729

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Chemotherapy monitoring by circulating tumor DNA analysis
Description: During the screening step (2nd chemotherapy line, cycle 1) : at each time point (L2C1D1 \& L2C1D15), 30 ml of blood will be drawn on special tubes with conservative suited for ctDNA analyses (e.g. STRECK® tubes).Then cell-free circulating DNA (cfcDNA) will be extracted from plasma following the manufacturer recommendations. cfcDNA will be quantified, and minimum 500-1000 copies will be analyzed by droplet digital PCR (ddPCR). Analyses will define if ctDNA could be detected during L2.~For the interventional step, from L3 (3rd chemotherapy line) : 20 ml of blood will be drawn at L3C1D1 and L3C1D15. If ctDNA at D15 shows a major drop (\> 40%) from D1, treatment will be continued. If ctDNA at D15 shows no major drop from D1, chemotherapy will be changed.
Study: NCT04865354

Intervention type: DEVICE
Group type: OTHER
Intervention: Verofilcon A contact lenses
Description: Spherical soft contact lenses for daily disposable wear

Intervention type: DEVICE
Group type: OTHER
Intervention: Verofilcon A contact lenses
Description: Spherical soft contact lenses for daily disposable wear

Intervention type: DEVICE
Group type: OTHER
Intervention: Somofilcon A contact lenses
Description: Spherical soft contact lenses for daily disposable wear

Intervention type: DEVICE
Group type: OTHER
Intervention: Somofilcon A contact lenses
Description: Spherical soft contact lenses for daily disposable wear
Study: NCT05126147

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxychloroquine
Description: Compare the effects of hydroxychloroquine 200mg twice daily for 6 months with those without treatment.
Study: NCT05933928

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simulation-based electronic fetal monitoring training
Description: Practices will be carried out with the students in the intervention group with the NOELLA Birth Simulator, which is a high-reality simulator located in the Simulation laboratory of the Department of Midwifery of the Faculty of Health Sciences of Hamidiye. A simulator will be practiced with a separate scenario including early, late, variable deceleration, reactive, sinusoidal and non-reactive trace interpretation and intervention.
Study: NCT04757636

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2.0 mg OPT-302
Description: intravitreal injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2.0 mg OPT-302
Description: intravitreal injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2.0 aflibercept
Description: intravitreal injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2.0 aflibercept
Description: intravitreal injection

Intervention type: BIOLOGICAL
Group type: SHAM_COMPARATOR
Intervention: 2.0 aflibercept
Description: intravitreal injection

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: intravitreal injection
Study: NCT04922203

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: in Situ Simulation
Description: 2 sessions of in situ simulation with 4 crisis scenarios and debriefing focused on non technical skills
Study: NCT04882579

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Point-of-care-ultrasound examination
Description: The intervention consists of three ultrasound modalities:~1. Cardiac ultrasound assessing signs of right ventricular strain or other obvious pathology.~2. Deep venous ultrasound assessing presence of a deep venous thrombus~3. Lung ultrasound assessing presence of pulmonary infarctions, pleural effusion, pneumothorax or interstitial syndrome.
Study: NCT05750927

Intervention type: PROCEDURE
Intervention: Transcatheter aortic valve intervention (TAVI) and percutaneous coronary intervention (PCI)
Description: TAVI and PCI to be administered as per physician's indication and choice, in one or more stages
Study: NCT05071183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TPX-0005
Description: Oral TPX-0005 capsules
Study: NCT04524195

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]F-AraG Injection
Description: Single dose of 5 mCi+/- \[18F\]F-AraG IV injection followed by the PET/CT scan. A baseline \[18F\]F-AraG PET/CT will be performed at about 0-7 days before patient receives the first dose of PD-1/PD-L1 immunotherapy. A second \[18F\]F-AraG PET-CT will be performed at less than 14 days after the first dose of PD-1/PD-L1 immunotherapy is administered and before the second dose of PD-1/PD-L1 immunotherapy is given.
Study: NCT05071183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trametinib
Description: Oral trametinib tablets
Study: NCT04307446

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Immersive Virtual Reality
Description: Immersive Virtual Reality

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Immersive Virtual Reality
Description: Immersive Virtual Reality
Study: NCT06400433

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided median nerve hydrodissection
Description: Injected wrist will be supinated and slightly dorsiflexed. The transducer of the ultrasound will be placed transversely at the proximal carpal inlet. After sterile preparation, a 22 gauge needle will be inserted using the short-axis technique, in-plane ulnar approach. During hydrodissection, separation of either between the median nerve and flexor retinaculum or between the median nerve and the underlying flexor tendons will be visually confirmed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided median nerve hydrodissection
Description: Injected wrist will be supinated and slightly dorsiflexed. The transducer of the ultrasound will be placed transversely at the proximal carpal inlet. After sterile preparation, a 22 gauge needle will be inserted using the short-axis technique, in-plane ulnar approach. During hydrodissection, separation of either between the median nerve and flexor retinaculum or between the median nerve and the underlying flexor tendons will be visually confirmed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided median nerve hydrodissection
Description: Injected wrist will be supinated and slightly dorsiflexed. The transducer of the ultrasound will be placed transversely at the proximal carpal inlet. After sterile preparation, a 22 gauge needle will be inserted using the short-axis technique, in-plane ulnar approach. During hydrodissection, separation of either between the median nerve and flexor retinaculum or between the median nerve and the underlying flexor tendons will be visually confirmed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided median nerve hydrodissection
Description: Injected wrist will be supinated and slightly dorsiflexed. The transducer of the ultrasound will be placed transversely at the proximal carpal inlet. After sterile preparation, a 22 gauge needle will be inserted using the short-axis technique, in-plane ulnar approach. During hydrodissection, separation of either between the median nerve and flexor retinaculum or between the median nerve and the underlying flexor tendons will be visually confirmed.
Study: NCT04881357

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: test mouth rinse (Lacer Oros Acción Integral - new formula, Barcelona, Spain).
Description: The experimental group will use three times daily a provided manual toothbrush with a sodium fluoride dentifrice, followed by the use of the test mouth rinse (Lacer Oros Acción Integral - new formula, Barcelona, Spain).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: control group
Description: The control group will use three times daily a provided manual toothbrush with a sodium fluoride dentifrice, followed by the use of the control mouth rinse (Lacer Oros Acción Integral - new formula, without active ingredients, Barcelona, Spain).
Study: NCT06042582

Intervention type: PROCEDURE
Intervention: Additional biopsies collection
Description: We will recruit only subjects (UC, CD and NO-UC/CD) scheduled for the endoscopy and biopsies-collection according to the usual clinical practice. During the endoscopy we will collect 6 additional biopsies.

Intervention type: PROCEDURE
Intervention: Additional biopsies collection
Description: We will recruit only subjects (UC, CD and NO-UC/CD) scheduled for the endoscopy and biopsies-collection according to the usual clinical practice. During the endoscopy we will collect 6 additional biopsies.

Intervention type: PROCEDURE
Intervention: Additional biopsies collection
Description: We will recruit only subjects (UC, CD and NO-UC/CD) scheduled for the endoscopy and biopsies-collection according to the usual clinical practice. During the endoscopy we will collect 6 additional biopsies.
Study: NCT06209229

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: sodium nucleinate
Description: * Calcitriol- 5000 units in the morning before meals every other day 21 days and the next 3 weeks after the end of therapy.~* Magnesium (in the form of lactate dihydrate) 470 mg + pyridoxine (in the form of hydrochloride) 5 mg - take orally 3 tablets per meter square of body surface area, in the evening 2 hours before bedtime, 21 days and the next 3 weeks after the end of therapy.~* Quercetin from onion juice - take orally 1000 mg in the morning before meals, 21 days, as well as the next 3 weeks after the end of therapy.~* sodium oligodinucleatide orally at the rate of 2 tablets under the tongue per meter square of body surface, in the morning 15 minutes before meals every other day, a total of 5 times (1, 3, 5, 7 , 9 day from the beginning of therapy), then after 21 days to repeat the course for 3 months.~* Spray natirium nucleonate 4 doses in the morning on the hyoid, suck, do not swallow for 3-5 minutes, once every 4 days for 21 days.
Study: NCT06583434

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: core-lower extremity Pilates Training Group
Description: Participants in this group will engage in a stabilization-based Pilates exercise program focusing on core and lower extremity stabilization. The program consists of twice-weekly sessions, each lasting 50 minutes, over a period of 8 weeks. The primary goal of the intervention is to improve gait patterns and balance in women with flexible pes planus
Study: NCT05142423

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK109+AK104
Description: It includes dose escalation and dose expansion stage. 6-12 patients will be enrolled in dose escalation stage for safety and efficacy. Then select specific dose of AK104 and AK109. Expand for the further safety and efficacy study.
Study: NCT05875233

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elix Daily Harmony
Description: Elix Daily Harmony is a clinical-strength, organic blend of hormone-balancing Traditional Chinese Medicine (TCM) herbs and adaptogens. Contains Angelica Sinensis, licorice, ginger, Bupleurum, Cyperus Rotundus, White Peony, Mint, Poria, Atractylodes, White Ginseng, Reishi, Rehmannia Root, and Astragalus.~Participants should add 3 droppers full (half a teaspoon or 2.5 ml) of Elix Daily Harmony to their tea or other warm or room temperature beverage each morning, 1-2 hours after their first meal. The product should not be taken with iced drinks or with food.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elix Daily Harmony
Description: Elix Daily Harmony is a clinical-strength, organic blend of hormone-balancing Traditional Chinese Medicine (TCM) herbs and adaptogens. Contains Angelica Sinensis, licorice, ginger, Bupleurum, Cyperus Rotundus, White Peony, Mint, Poria, Atractylodes, White Ginseng, Reishi, Rehmannia Root, and Astragalus.~Participants should add 3 droppers full (half a teaspoon or 2.5 ml) of Elix Daily Harmony to their tea or other warm or room temperature beverage each morning, 1-2 hours after their first meal. The product should not be taken with iced drinks or with food.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elix Cycle Balance
Description: A tailored blend of medicinal herbs to holistically support menstrual symptoms by treating underlying imbalances. Participants should take 3 droppers full (half a teaspoon or 2.5 ml) of Elix Cycle Balance daily before bed with tea or other warm or room temperature beverage. The product should not be taken with iced drinks or with food.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elix Cycle Balance
Description: A tailored blend of medicinal herbs to holistically support menstrual symptoms by treating underlying imbalances. Participants should take 3 droppers full (half a teaspoon or 2.5 ml) of Elix Cycle Balance daily before bed with tea or other warm or room temperature beverage. The product should not be taken with iced drinks or with food.
Study: NCT06583434

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-Training Group
Description: Participants in this group will not receive any specific intervention during the study period. They will continue their usual activities without any additional exercises provided by the study.
Study: NCT06106763

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mandala coloring
Description: Mandala coloring page