TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05496855

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional follow-up
Description: Patients in the conventional/usual care arm will be treated according to current conventional follow-up regimen with PROs, blood tests, and face-to-face visits with an experienced nurse or a rheumatologist every 6 months. They can contact the hospital if they are experience worsening of their disease.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote monitoring
Description: The patients in the remote monitoring arm will use a web-app (Youwell) for self-reporting patient reported outcomes (PROs) and CRP/ESR, displaying results for PROs over time, and for synchronous (video) or asynchronous (chat) communication with healthcare providers. The patients will receive a SMS reminder for tasks (e.g., self-reporting PROs or registering results from blood tests) every month.~A study coordinator/nurse will monitor the PROs and blood test (CRP/ESR) results, and respond to chat messages. Based on the algorithm, a triaging functionality in the Youwell platform will aid healthcare providers in highlighting which patients needs attention.
Study: NCT05419284

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GAPP+Care
Description: standard physiotherapy 45 minutes per day, 5 day a week (GAPP)~+ 3 extra exercise sessions led by a caregiver (+Care)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: +Care
Description: 3 extra exercise moments led by a caregiver: one physiotherapist-caregiver-patient exercise session: the physiotherapist will educate and train the caregiver on the exercises and hands-on skills.~Two caregiver-patient exercise sessions

Intervention type: OTHER
Group type: OTHER
Intervention: Observation of GAPP+Care
Description: Healthcare workers in the geriatric rehabilitation ward will be interviewed on their opinions on GAPP+Care
Study: NCT06608537

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: neoadjuvant SCRT followed by Sintilimab plus CAPOX
Description: Patientsreceived neoadjuvant treatment consisting of SCRT (a total of 25 Gy in 5 days) followed by sintilimab (3mg/kg intravenous drip on day 1; every 3-week cycle for two cycles) combined with CAPOX (oxaliplatin 130 mg/m2 intravenous infusion over 2 h on day 1, capecitabine 1000 mg/m2 orally twice daily from day 1-14, in every 3-week cycle for two cycles) 1 week later.
Study: NCT06593639

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prehabilitation before surgery
Description: Prehabilitation multimodal program will start about 4 weeks before the surgery and will be continued until 2 weeks after the surgical intervention. Multimodal program comprises physical exercise, nutritional intervention, and psychological support provided before and during curative treatment for HNC patients.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prehabilitation before and during CRT
Description: Prehabilitation multimodal program will start about 4 weeks CRT and will be continued in parallel until 2 weeks after the end. Multimodal program comprises physical exercise, nutritional intervention, and psychological support provided before and during curative treatment for HNC patients.
Study: NCT06598878

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: AR gait training
Description: Participants will walk on a pathway projected in augmented reality (AR), following the instructions provided on the pathway Each session will last for 60 minutes, conducted three times per week, over a period of six weeks.
Study: NCT06633029

Intervention type: DEVICE
Intervention: Prismaflex HF20
Description: CRRT fluid management and reduction of uremic toxins.

Intervention type: DEVICE
Intervention: Prismaflex M60
Description: CRRT fluid management and reduction of uremic toxins.
Study: NCT06632392

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simulation training
Description: Theory and simulation training

Intervention type: OTHER
Group type: OTHER
Intervention: Theory training
Description: Theory training

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Theory training
Description: Theory training
Study: NCT06633068

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Adding perineural Nalbuphine to Bupivacaine in superficial cervical nerve block
Description: Adding nalbuphine as an adjuvant to bupivacaine in superficial cervical plexus block during thyroid surgeries

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adding perineural Nalbuphine to Bupivacaine in superficial cervical nerve block
Description: Adding nalbuphine as an adjuvant to bupivacaine in superficial cervical plexus block during thyroid surgeries
Study: NCT06633679

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Se Cuida Intervention
Description: The intervention consist in an internet based cognitive behavioural therapy program delivered through a online platform. Intervention consist of 8 weeks with 8 weekly modules assigned to the participants. The program has been translated and adapted to the Brazilian and is based on CBT techniques focused on managing psychological symptoms of anxiety and depression in young people. Out of a total 14 modules adaptaded, 8 will be delivered in the treatment: 5 will be available to all participants and 3 will be tailored according to the initial assessment and interviews. The intervention is self-guided with support on demand, meaning that when participants need support, they could chat directly through the platform text message channel with a psychoteraphist responsible for them. Also, once a week each participants receive feedbacks regarding their work on the program\&#39;s exercises.
Study: NCT06633172

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: laparoscopic ventral mesh rectopexy
Description: performing ventral mesh rectopexy via laparoscopic surgery to correct the anterior rectocele.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Trans vaginal repair
Description: performing repair of the rectocele through the recto vaginal septum repair.
Study: NCT06632899

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: combined physical and cognitive training and 1 hour of risk factor prevention and healthy lifestyle development
Description: Dosage: a 2-hour session once a week for 12 weeks. Each multidomain intervention session includes 1 hour of combined physical (balance, strength and aerobic exercises) and cognitive (attention, memory, calculation, visual-spatial ability, processing speed and executive function) training and 1 hour of risk factor prevention (nutrition, chronic disease management, oral health, fall prevention and transportation safety, psychosocial factors and sleep) and healthy lifestyle development (Discussion and sharing on topics such as self-health management, goal setting, and the health journal.)
Study: NCT06632847

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IMT based Resistance training
Description: IMT with device group is trained twice daily, with the morning session and afternoon session. The intensity will increase progressively in this group, starting at 60% Maximal Inspiratory Pressure (MIP) and reaching 75% by the end of study. POSITION: Patient will be in sitting position. FREQUENCY: 4 TO 5 times per week. INTENSITY: 60 to 75% of MIP (gradually increment the load by 10%every 2 weeks to reach 75 to 80 %MIP). Time: 15 to 20 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Theraband Resistive training
Description: IMT training is form of exercise designed to strengthen the muscle that are involve in inhalation, primarily the diaphragm and intercostal muscles. Thera-band resistive training perform twice daily, with morning and afternoon session. Training will be perform 3 times per week. POSITION: patient will be in standing position. INTENSITY: moderate intensity (black and green thera-band used to provide medium resistance). Time: 15 to 20 minutes
Study: NCT06251492

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy
Description: 8 Gray x 3 for 2 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Adebrelimab 20mg/kg IV Q3W for 2 cycles, then Adebrelimab 20mg/kg IV alone Q3W until progression
Study: NCT06241560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1015550
Description: BI 1015550

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirfenidone
Description: Pirfenidone
Study: NCT06286800

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation (tDCS) with OT
Description: Weak direct current (0.5-2 mA) will be delivered for up to 20 minutes through surface electrodes which will be positioned using the ptDCS montage. The current will be increased and decreased ramp-like at the beginning and end of the 20-minute stimulation to lessen the itchy/numb skin sensation and decrease the likelihood of an innocuous phosphene-like visual phenomenon. The stimulation will be delivered during the first 20 minutes of occupational therapy targeted to the more affected upper extremity.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham tDCS with OT
Description: Same procedure and montage as with the active stimulation but the current will be increased then decreased ramp-like and switched off after 20 seconds instead of the 20 minutes to elicit the same cutaneous sensation as the other stimulation conditions. \[69\] This short length of stimulation is documented to elicit sensations comparable to those of real stimulation. With this procedure, subjects were unable to differentiate between tDCS and sham stimulation in our and other previous studies.
Study: NCT06285253

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: miroliverELAP treatment
Description: Subject's blood will be perfused through a bioengineered liver graft via an extracorporeal blood circuit.
Study: NCT05104866

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dato-DXd
Description: Experimental drug. Provided in 100mg vials. IV infusion.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: Tablet. Oral route of administration. Active comparator

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gemcitabine
Description: IV Infusion. Active comparator

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Eribulin
Description: IV Infusion. Active comparator

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vinorelbine
Description: IV Infusion. Active comparator
Study: NCT06127602

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reactive balance training with Neuromuscular Electrical Stimulation
Description: REACT-NMES group: The ActiveStep treadmill will be used to deliver slips during all sessions. Each subject will experience three levels of perturbations over 12 sessions (24 slips/session) in progressive ascending way. On the first week, subjects will start with the lowest displacement level (6 cm) and move up to the next level (12 cm) by week 2 if they have \< 5 falls out of 8 slips at the previous level. By week 3, subjects are expected to move to level 3 (24 cm) and train at that for weeks 3 to 6. If subjects don't move up a level, training will continue at the lower level. NMES will be delivered to the vastus lateralis synchronously with the perturbation, which will always occur 50 ms after slip-onset and last for 450 ms including the period between liftoff to touchdown of the first compensatory step.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Reactive balance training without Neuromuscular Electrical Stimulation
Description: REACT group: The REACT group will undergo the same reactive balance training (in terms of type, dosage: intensity, frequency) as the REACT-NMES group. The only difference will be that the REACT group will receive ShamNMES for same time after the compensatory step touchdown. The ActiveStep treadmill will be used to deliver slips during all sessions. Each subject will experience three levels of perturbations over 12 sessions (24 slips/session) in progressive ascending way. On the first week, subjects will start with the lowest displacement level (6 cm) and move up to the next level (12 cm) by week 2 if they have \< 5 falls out of 8 slips at the previous level. By week 3, subjects are expected to move to level 3 (24 cm) and train at that for weeks 3 to 6. If subjects don't move up a level, training will continue at the lower level.
Study: NCT04958317

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Early exercise
Description: Participants will exercise for 30 minutes prior to an evening meal.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Late exercise
Description: Participants will exercise for 30 minutes after an evening meal.
Study: NCT06499441

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial induction in gastrocnemius
Description: A 3-pass shallow leg gliding technique was applied first, followed by 5 minutes of the deep myofascial calf induction technique described by Pilat.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preassure release
Description: Also called ischaemic pressure. Three cycles of pressure are applied to the trigger point of the gastrocnemius muscle until the pain disappears on pressure.
Study: NCT05425953

Intervention type: OTHER
Intervention: No intervention other than obtaining biopsies
Description: Biopsies will be obtained.
Study: NCT05727527

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local Anesthesia 1
Description: Local anesthesia injection after applying a candy flavor
Study: NCT05425953

Intervention type: OTHER
Intervention: No intervention other than obtaining biopsies
Description: Biopsies will be obtained.

Intervention type: OTHER
Intervention: No intervention other than obtaining biopsies
Description: Biopsies will be obtained.

Intervention type: OTHER
Intervention: No intervention other than obtaining biopsies
Description: Biopsies will be obtained.

Intervention type: OTHER
Intervention: No intervention other than obtaining biopsies
Description: Biopsies will be obtained.

Intervention type: OTHER
Intervention: No intervention other than obtaining biopsies
Description: Biopsies will be obtained.
Study: NCT05296889

Intervention type: DEVICE
Intervention: posterior stabilization for the cervical spine
Description: The Ennovate® Cervical Spinal System is a posterior stabilization for the cervical and upper-thoracic spine. The implants are used for the posterior monosegmental and multisegmental stabilization of the occipitocervical junction and of the cervical and upper thoracic spine.
Study: NCT06324786

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IBMT
Description: IBMT is an effortless mindfulness technique
Study: NCT06488092

Intervention type: OTHER
Intervention: Cesarean Risk Calculator
Description: The cesarean risk calculator will be incorporated into routine care at the site
Study: NCT06194942

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chiropractic manipulation
Description: Chiropractic manipulation is a manual therapy technique commonly used by chiropractors. It involves the application of controlled, sudden force to a specific joint, often with the goal of improving joint function, reducing pain, and promoting overall musculoskeletal health.In the context of thoracic chiropractic manipulation, the chiropractor focuses on the vertebrae and joints in the thoracic spine.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: sham manipulation
Description: Sham manipulation refers to a simulated or placebo form of a manual therapy intervention, often used in research studies, especially in clinical trials involving chiropractic or physical therapy. the term sham manipulation likely implies a procedure that mimics the physical aspects of a real chiropractic manipulation but does not involve the actual therapeutic forces or movements.~The chiropractic treatment group received thoracic chiropractic manipulations (HVLA) twice a week for a total of six sessions over three weeks, while the control group received sham manipulations.
Study: NCT04676087

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extracorporeal Photopheresis
Description: Undergo ECP

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mogamulizumab
Description: Given IV

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT05568680

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SynKIR-110, Autologous T cells Transduced with Mesothelin KIR-CAR
Description: Autologous T cells Transduced with Mesothelin KIR-CAR
Study: NCT05727527

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local Anesthesia 1
Description: Local anesthesia injection after applying a candy flavor

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local Anesthesia 2
Description: Local anesthesia injection after applying sterile water
Study: NCT06324786

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IBMT
Description: IBMT is an effortless mindfulness technique

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NF
Description: NF is a mental training technique.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NF
Description: NF is a mental training technique.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: NF
Description: NF is a mental training technique.
Study: NCT05958888

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text only sodium label
Description: Warning: High in sodium. is shown in a black square label on the can of soup.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Icon sodium label
Description: Warning: High in sodium. is shown beneath a yellow triangle icon with an exclamation mark all in a black square label on the can of soup.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pictorial sodium label
Description: Warning: High in sodium. is shown beneath an image of a spilled salt shaker, all in a black square label on the can of soup.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Barcode label
Description: Barcode is shown in white square label on the can of soup
Study: NCT06112496

Intervention type: DEVICE
Intervention: EMG
Description: Neuro-EMG-Micro, Neurosoft, Ivanovo, Russia, will be used for the assessment of muscle activity for muscles.

Intervention type: DEVICE
Intervention: EMG
Description: Neuro-EMG-Micro, Neurosoft, Ivanovo, Russia, will be used for the assessment of muscle activity for muscles.
Study: NCT05727527

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local Anesthesia 2
Description: Local anesthesia injection after applying sterile water
Study: NCT04857840

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Firibastat (QGC001) Period 1
Description: 1000 mg (2 x 500 mg) tablets QD per Os
Study: NCT06230887

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Building Spiritual Strength
Description: Spiritually Integrated group intervention for moral injury

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Present Centered Group Therapy
Description: Active control, manualized evidence-based coping skills intervention for PTSD
Study: NCT04857840

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Firibastat (QGC001) Period 1
Description: 1000 mg (2 x 500 mg) tablets QD per Os
Study: NCT05022693

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BIO89-100
Description: Subcutaneous Injections
Study: NCT05415865

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Alkalinized Lidocaine
Description: 20 ml of Lidocaine Hydrochloride and 10 ml of Sodium hydrogen carbonate will be pulled up and mixed in a syringe on site, and 30 ml mixed solution in total will afterwards be installed in the bladder with a catheter.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Alkalinized Lidocaine
Description: 20 ml of Lidocaine Hydrochloride and 10 ml of Sodium hydrogen carbonate will be pulled up and mixed in a syringe on site, and 30 ml mixed solution in total will afterwards be installed in the bladder with a catheter.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Sodium Chloride 0.9% Inj
Description: 20 ml of Sodium Chloride 9 g/L and 10 ml of Sodium Chloride 9 g/L will be pulled up and mixed in a syringe on site, and 30 ml solution in total will afterwards be installed in the bladder with a catheter.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Sodium Chloride 0.9% Inj
Description: 20 ml of Sodium Chloride 9 g/L and 10 ml of Sodium Chloride 9 g/L will be pulled up and mixed in a syringe on site, and 30 ml solution in total will afterwards be installed in the bladder with a catheter.
Study: NCT06411106

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMIQUIMOD cream 50mg/g
Description: 5 mg imiquimod (100mg Aldara®) per treatment site with a 12mm Finn chamber
Study: NCT05940857

Intervention type: DEVICE
Intervention: OCS Liver
Description: The TransMedics® Organ Care System (OCS) Liver is an FDA approved portable extracorporeal liver perfusion and monitoring system.
Study: NCT06096090

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Interleukin-2
Description: Low dose Interleukin-2 (Aldesleukin) administration to expand Regulatory T cells

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Interleukin-2
Description: Low dose Interleukin-2 (Aldesleukin) administration to expand Regulatory T cells

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administration
Study: NCT06446375

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: FIFA 11+ KIDS Training Protocol consists of seven different exercises: three for unilateral, dynamic stability of the lower limbs (hopping, jumping and landing); three for whole body and trunk strength/stability; and one exercise on falling technique.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regular daily activity
Description: Regular physical activity
Study: NCT06242990

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Y-PATH NI
Description: The Y-PATH NI intervention provides a whole of school approach with student, teacher, parent and guardian components. Student components: Y-PATH resources delivered by physical education teachers (6 lesson plans, resource cards to use as teaching prompts), student handbook. Posters are also displayed in the sports hall/ PE department.~Teacher components: Teachers will receive online and in-person training to deliver the Y-PATH programme. This component also targets all non-specialist PE teachers and includes workshops, information leaflets, development of a physical activity promotion charter and a step challenge.~Parent/guardian components: Information session and leaflets distributed across the intervention period.
Study: NCT05292495

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HR17031 injection
Description: HR17031 injection; administered subcutaneously.