TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05426369

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein
Description: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein for injection (Strength: 1 mg/ml, 0.5ml/vial)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein
Description: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein for injection (Strength: 1 mg/ml, 0.5ml/vial)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein
Description: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein for injection (Strength: 1 mg/ml, 0.5ml/vial)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein
Description: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein for injection (Strength: 1 mg/ml, 0.5ml/vial)
Study: NCT04677530

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-40411813
Description: JNJ-40411813 will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-40411813
Description: JNJ-40411813 will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-40411813
Description: JNJ-40411813 will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Matching Placebo
Description: Matching placebo will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Matching Placebo
Description: Matching placebo will be administered orally.
Study: NCT04696458

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus plantarum (CECT7484 and CECT7485)/ Pediococcus acidilactici (CECT7483)
Description: Probiotic Capsules in blister packets of capsules containing the probiotic intervention contain a combination of three strains of lactic acid bacteria: two Lactobacillus plantarum (CECT7484 and CECT7485) and one Pediococcus acidilactici (CECT7483).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: Placebo
Description: Placebo Capsules in blister packets of capsules containing the inert (controlled) non-interventional treatment.
Study: NCT05869552

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STAT-PC
Description: STAT-PC is an adapted version of Suicidal Teens Accessing Treatment after an ED Visit (STAT-ED). It is a brief intervention based on motivational interviewing (MI) that focuses on mental health care seeking behavior, problem-solving, and referrals plus brief case management. The intervention will consist of an initial session with the youth focusing on accessing mental health care plus case management calls. The interventionist will also be available to assist with referrals for connection to other services later during the study period as needed for up to three months. The intervention may include contact with the youth's mental health provider to make sure linkages are made.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: YST-III
Description: YST-III is an adapted version of Youth-Nominated Support Team for Suicidal Adolescents (YST-II). The intervention is a brief intervention originally developed for youth who have been psychiatrically hospitalized due to a suicide attempt or suicidal ideation (SI). Participants will nominate supportive adults (age 18 and older) from their lives who agree to provide ongoing contact and support for up to 3 months. YST-III will include an introductory session with the youth who will nominate their support persons plus referrals for mental health services. The support persons will receive training and support on how to best support their youth partner and then ongoing calls to support them in working with their youth partner for up to 3 months.
Study: NCT05378516

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT05524740

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-785-7
Description: Treatment with the BTL-785F device with the BTL-785-7 applicator for improvement of the structure of facial muscles.
Study: NCT06303947

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-esophageal Tube
Description: The group was given enteral nutritional support with Intermittent Oro-esophageal Tube according to the following procedure: Before each feeding, inside and outside of the tube was cleaned with water. During feeding, the patient should maintain a semi-reclining or sitting position with mouth opened, and the tube was inserted slowly and smoothly into the upper part of the esophagus by medical staffs while the appropriate depth of intubation was checked with the calibration markings on the tube wall. The distance from the incisors to the head part of the tube should be between 22-25 cm. However, the specific depth should be evaluated based on patients' feedback and adjusted accordingly. After insertion, the tail part of the tube should be put into a container full of water and the absence of continuous bubbles indicated a successful intubation. Then, the feeding was to be conducted three times per day with 50 ml per minute and 400-600ml for each feeding.
Study: NCT05451732

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nanofat grafting
Description: Naofat grafting in the urethral stricture. The autologous adipose tissue is transferred by injection and in this way, the access to the urethral stricture is carried out with a minimal incision of the male urethra while in the female urethra is transferred exclusively with injections, without incision of urethral tissue.
Study: NCT06300788

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PPI and T50 dosing
Description: Sampling for PPI determination and T50 in blood and urine.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PPI and T50 dosing
Description: Sampling for PPI determination and T50 in blood and urine.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PPI and T50 dosing
Description: Sampling for PPI determination and T50 in blood and urine.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PPI and T50 dosing
Description: Sampling for PPI determination and T50 in blood and urine.
Study: NCT05932082

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: myomectomy or not
Description: The study group receive myomectomy, while the control group don't receive myomectomy.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: myomectomy or not
Description: The study group receive myomectomy, while the control group don't receive myomectomy.
Study: NCT05111873

Intervention type: OTHER
Intervention: multimodal treatment
Description: combination of medical consultations, psychological therapy, physiotherapy, occupational therapy, disease specific education und progressive muscle relaxation
Study: NCT03943901

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab is a monoclonal antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Chemotherapy drug, alkylating agent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Chemotherapy drug, anthracycline antibiotic

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Chemotherapy drug, plant alkaloid

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Steroid, anti-inflammatory

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pegfilgrastim
Description: Granulocyte stimulating factor, biologic response modifier
Study: NCT06497309

Intervention type: DEVICE
Intervention: Treadmill training
Description: Therapy with treadmill-based advanced technology device.

Intervention type: DEVICE
Intervention: Overground training
Description: Therapy using an advanced technological device enables exercise on the ground.

Intervention type: DEVICE
Intervention: DIERS
Description: The examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability.

Intervention type: DEVICE
Intervention: DIERS
Description: The examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability.

Intervention type: OTHER
Intervention: Traditional physiotherapy assessments
Description: Traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.

Intervention type: OTHER
Intervention: Traditional physiotherapy assessments
Description: Traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.
Study: NCT06535542

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Whole Genome Sequencing
Description: Participants in this arm will have their blood sample analyzed by whole-genome sequencing (WGS) and will be given access to Predictiv™ Deoxyribonucleic acid (DNA)-based digital twin platform, a web-based interactive application with WGS results. The platform will include positive monogenic and polygenic Familial Hypercholesterolemia results and pharmacogenomics results on statins and clopidogrel. A report of positive monogenic variants will be included in their medical record. This may also include genes on the American College of Medical Genetics and Genomics (ACMG) secondary findings (SF) version 3.2 list if the participant consents to receive these incidental findings. The report will only include pathogenic, likely pathogenic, and variant of uncertain significance (VUS) results.
Study: NCT06552260

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Troriluzole
Description: Tripeptide prodrug of Riluzole, 100 mg capsule, taken orally per protocol.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Troriluzole
Description: Tripeptide prodrug of Riluzole, 100 mg capsule, taken orally per protocol.
Study: NCT05662150

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Low frequency repetitive stimulation
Description: Neuromuscular transmission was tested by using short-lasting low frequency RNS (10 stimuli at 3 Hz). The test was applied on the abductor digiti minimi (ADM), anterior tibial, orbiculis oculi, trapezius, anconeus and EDB muscles of one side, in this particular order, by supramaximal stimulation of the corresponding nerve.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Low frequency repetitive stimulation
Description: Neuromuscular transmission was tested by using short-lasting low frequency RNS (10 stimuli at 3 Hz). The test was applied on the abductor digiti minimi (ADM), anterior tibial, orbiculis oculi, trapezius, anconeus and EDB muscles of one side, in this particular order, by supramaximal stimulation of the corresponding nerve.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Low frequency repetitive stimulation
Description: Neuromuscular transmission was tested by using short-lasting low frequency RNS (10 stimuli at 3 Hz). The test was applied on the abductor digiti minimi (ADM), anterior tibial, orbiculis oculi, trapezius, anconeus and EDB muscles of one side, in this particular order, by supramaximal stimulation of the corresponding nerve.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Low frequency repetitive stimulation
Description: Neuromuscular transmission was tested by using short-lasting low frequency RNS (10 stimuli at 3 Hz). The test was applied on the abductor digiti minimi (ADM), anterior tibial, orbiculis oculi, trapezius, anconeus and EDB muscles of one side, in this particular order, by supramaximal stimulation of the corresponding nerve.
Study: NCT04525651

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital Acupuncture Manipulation Therapeutic Instrument
Description: The device is based on the characteristics of traditional acupuncture manipulation of Shanghai School of Traditional Chinese Medicine, and absorbs the information of the techniques of famous experts, modulates the stimulation waveform of the electroacupuncture device by modulating the signal, and realizes the digitization of acupuncture technique information.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual Acupuncture
Description: Manual acupuncture to acheive de qi.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Acupuncture
Description: Sham acupuncture to avoid de qi.
Study: NCT04877496

Intervention type: DRUG
Intervention: History of exposure to anti-CD20 treatment since 01/01/2010
Description: Intravenous treatment history of anti-CD20 treatment since 01/01/2010

Intervention type: BIOLOGICAL
Intervention: Completion of COVID19 vaccine at least 4 weeks ago
Description: Completion of COVID19 vaccination course at least 4 weeks ago.

Intervention type: BIOLOGICAL
Intervention: Completion of COVID19 vaccine at least 4 weeks ago
Description: Completion of COVID19 vaccination course at least 4 weeks ago.
Study: NCT04660760

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Given IV

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Complete questionnaires

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Complete questionnaires

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ramucirumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Ramucirumab
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trifluridine and Tipiracil Hydrochloride
Description: Given PO
Study: NCT04960670

Intervention type: OTHER
Intervention: Evaluation of microbiome and maternal/infant lifestyle
Description: Identification of the longitudinal interplay between the intestinal microbiome and infant/maternal nutritional and lifestyle habits, environmental factors exposure and anthropometric measurements, in children with adiposity rebound vs children with early adiposity rebound.
Study: NCT06193707

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the Remote Intervention
Description: Remote health intervention refers to the use of big data, artificial intelligence and 5G technology to provide healthcare services and interventions to individuals at a distance. This approach allows healthcare providers to deliver medical care, monitor patients' health, offer consultations, provide education, and offer support without the need for in-person interaction.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: the Traditional Intervention
Description: Ultrasound follow-up review is recommended. If there is suspicious change in the lesion during follow-up, biopsy should be considered to clarify the nature of the pathology.
Study: NCT05340413

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: 300mg twice daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olaparib
Description: 300mg twice daily
Study: NCT05905562

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stabilization exercises
Description: Core muscles activation exercises will be performed on patients to target the abdominals.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal mobilization techniques
Description: lumbar spine joint mobilization techniques will be performed to patient in prone lying.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal mobilization techniques
Description: lumbar spine joint mobilization techniques will be performed to patient in prone lying.
Study: NCT04804527

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intensified physiotherapy
Description: Physiotherapy x2

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care physiotherapy
Description: Physiotherapy x1
Study: NCT05378113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ondansetron
Description: Ondansetron (Zofran) is a 5-hydroxytryptamine-3 (5-HT3) receptor antagonist commonly used to treat postoperative nausea and vomiting.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine
Description: Lidocaine is a local anesthetic agent used intravenously prior to the propofol injection. Currently the standard of care to help decrease the severity of pain in the injection site, a common side effect of propofol.
Study: NCT04715126

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oxyjun
Description: One capsule to be taken after breakfast with water.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One capsule to be taken after breakfast with water.
Study: NCT06181747

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a serious mobile device-based game prototype (Save the Muse Home)
Description: The cognitive impairment corresponding to the symptoms, which we are interested in, focuses on executive inhibition, motor inhibition, sustained attention, selective attention, working memory, and planning ability. The training content will be presented in different scenarios as effective training components. The story line of the warrior breakthrough runs through the whole game, each level is adapted according to the functional damage areas of different patients, and each level involves reward and punishment mechanisms to keep the interest of the players, the difficulty gradient of each level is kept moderate, and the game includes design elements such as space, time, object attributes, actions, rules, skills, and probabilities, etc., which ultimately completes Save the Muse Home, a serious game for the treatment of ADHD.
Study: NCT06303947

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric tube
Description: The group is given enteral nutritional support with Nasogastric tube according to the relevant guidelines. Within 4 hours after admission, the placement of the feeding tube was conducted by professional medical staffs and after intubation, the tube was secured to the patient's cheek with medical tape. The feeding was conducted once every 3-4 hours, with 200-300ml each time. The total feeding volume was determined based on daily requirements. The feeding content was formulated by the nutritionists based on the patient's condition and relevant guidelines to reach the energy demand as 20-25 kcal/kg/day and protein supplementation of 1.2-2.0 g/kg/day for both two groups. For patients with limited tube feeding compliance, we made appropriate adjustments to ensure that they were not at risk of severe malnutrition as much as possible.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comprehensive rehabilitation training
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Comprehensive rehabilitation training
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.
Study: NCT05835245

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryoablation
Description: Cryoablation is performed under US or CT guidance per Investigator decision.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: a PD-1 immune check inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Lenvatinib capsules
Study: NCT05829759

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-B6
Description: Participants will be part of the Tele-B6 intervention that includes six group sessions delivered over the course of six weeks. Survey assessments for the intervention group (first phase) will be conducted at enrollment (baseline), 2 months (immediate post-intervention survey), 4 months (interim-survey, post-intervention), and 6 months (endline).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Delayed intervention (waitlist control)
Description: Wait-list control participants will be assigned to a group for initiation of the full intervention beginning at month 4 after their enrollment (i.e., beginning after they, and their corresponding intervention group, have completed their intervention and two follow-up surveys). Wait-list control participants will complete surveys at enrollment (baseline), 2 months (pre-intervention), 4 months (preintervention), 6 months (immediate post-intervention), and 8 months (post-intervention).
Study: NCT06237387

Intervention type: OTHER
Intervention: Periodontal examination
Description: Determining the patient's oral hygiene status and the severity of gingivitis. For this purpose, the non-invasive Löe-Silness plaque and gingival index system will be used.
Study: NCT06056349

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam oral solution
Description: Buccal administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ClonazePAM Oral Product
Description: Orodispersable

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual medication/ traditional
Description: Medication that is usually used in the emergency department
Study: NCT06237387

Intervention type: OTHER
Intervention: Periodontal examination
Description: Determining the patient's oral hygiene status and the severity of gingivitis. For this purpose, the non-invasive Löe-Silness plaque and gingival index system will be used.

Intervention type: OTHER
Intervention: Periodontal examination
Description: Determining the patient's oral hygiene status and the severity of gingivitis. For this purpose, the non-invasive Löe-Silness plaque and gingival index system will be used.
Study: NCT04668001

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-Infrared Transcranial Photobiomodulation
Description: tPBM-NIR involves the use of a device that administers near-infrared light over the scalp. The light activates target brain regions.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham Transcranial Photobiomodulation
Description: tPBM-Sham involves the use of an identical device to tPBM-NIR but does not administer near-infrared light. It mimics the sensation by applying heat but does not actually activate target regions of the brain