TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05278806

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Equity Dashboard, Population Health Coordinator and Community Health Worker Support
Description: Providers will be given access to an equity dashboard that displays their practice's performance on ambulatory quality metrics stratified by race and language.~Population health coordinators (PHCs) will lead equity huddles with providers to review list of patients who are not at goal for their hypertension control and meet the inclusion criteria. Providers will formulate a follow up plan for each patient that the PHCs will help implement. For example, PHCs may contact patient via the online patient portal or phone to obtain recent home blood pressure readings, facilitate scheduling of follow up visits, etc.~In addition, patients may be referred to the community health worker (CHW) hypertension management program. Patients will work with the CHW for 3-6 months. During this time the CHW will focus their efforts on patient education/coaching, remote blood pressure monitoring, addressing psychosocial and socioeconomic barriers to care and care coordination.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Equity Dashboard and Population Health Coordinator Support
Description: Providers will be given access to an equity dashboard that displays their practice's performance on ambulatory quality metrics stratified by race and language.~In addition, population health coordinators (PHCs) will lead disparities focused huddles with providers. During the huddle, they will review list of patients who are not at goal for their hypertension control and meet the inclusion criteria. Providers will then formulate a follow up plan for each patient that the Population Health Coordinators will help implement. For example, PHCs may contact patient via the online patient portal or phone to obtain recent home blood pressure readings, facilitate scheduling of follow up visits, etc.
Study: NCT06063889

Intervention type: DIAGNOSTIC_TEST
Intervention: Maximal Rate of Force Development Test for Ankle Muscles
Description: This test is designed to measure the maximal rate of force development in the ankle muscles, specifically the plantar flexors. It aims to assess the relationship between the strength of these muscles and the functional ability in patients with knee osteoarthritis. The results from this test will help to understand how lower limb muscle strength influences the symptoms and progression of knee osteoarthritis.

Intervention type: DIAGNOSTIC_TEST
Intervention: Maximal Rate of Force Development Test for Ankle Muscles
Description: This test is designed to measure the maximal rate of force development in the ankle muscles, specifically the plantar flexors. It aims to assess the relationship between the strength of these muscles and the functional ability in patients with knee osteoarthritis. The results from this test will help to understand how lower limb muscle strength influences the symptoms and progression of knee osteoarthritis.
Study: NCT06208397

Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic Resonance Elastography and routine MRI
Description: Assessed boundary conditions through MRE-base SII before surgery and recorded HGP of tumor after surgery.
Study: NCT06181487

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Functional Training
Description: 12 weeks of high-intensity functional training, 3 times/week. Each class lasts 60 minutes, including warm-up, physical training, and cool down.
Study: NCT04847206

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3,4-methylenedioxymethamphetamine
Description: A moderate dose of 100 mg MDMA will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3,4-methylenedioxyamphetamine
Description: A moderate dose of 93.9 mg MDA will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lysine-3,4-methylenedioxymethamphetamine
Description: A moderate dose of 171.7 mg lysine-MDMA will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lysine-3,4-methylenedioxyamphetamine
Description: A moderate dose of 165.6 mg lysine-MDA will be administered.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (Mannitol)
Study: NCT04338659

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IBI322 Recombinant anti-human CD47/PD-L1 bispecific antibody injection
Description: IBI322 Recombinant anti-human CD47/PD-L1 bispecific antibody injection
Study: NCT05278039

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Respiratory-Swallow Phase Training
Description: Participants will complete 6 respiratory-swallow phase training sessions that will last approximately one hour.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Swallow Practice
Description: Participants will complete 6 swallow practice sessions that will last approximately one hour.
Study: NCT05046808

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib Malate Capsules
Description: Famitinib Malate Capsules 10mg single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib Malate Capsules
Description: Famitinib Malate Capsules 15mg single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib Malate Capsules
Description: Famitinib Malate Capsules 20mg single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib Malate Capsules
Description: Famitinib Malate Capsules 10mg\*2 single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib Malate Capsules
Description: Famitinib Malate Capsules 25mg single dose
Study: NCT00003858

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mitoxantrone hydrochloride
Study: NCT04421443

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Description: This intervention focuses on a wide range of emotional psychopathology, allowing care for comorbid disorders and subclinical or unspecified symptoms, which reduces treatment times and costs, and improves response to treatment. The intervention will be carried out in an online-group format. For ethical reasons, if any of the patients feel uncomfortable during the study with the online-group format, will may leave the group and receive individual attention. The study plans follow-ups every three months until two years after post-treatment, all of them will be conducted online.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Description: This intervention focuses on a wide range of emotional psychopathology, allowing care for comorbid disorders and subclinical or unspecified symptoms, which reduces treatment times and costs, and improves response to treatment. The intervention will be carried out in an online-group format. For ethical reasons, if any of the patients feel uncomfortable during the study with the online-group format, will may leave the group and receive individual attention. The study plans follow-ups every three months until two years after post-treatment, all of them will be conducted online.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Description: This intervention focuses on a wide range of emotional psychopathology, allowing care for comorbid disorders and subclinical or unspecified symptoms, which reduces treatment times and costs, and improves response to treatment. The intervention will be carried out in an online-group format. For ethical reasons, if any of the patients feel uncomfortable during the study with the online-group format, will may leave the group and receive individual attention. The study plans follow-ups every three months until two years after post-treatment, all of them will be conducted online.
Study: NCT05310149

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prosthetic intervention with maxillary obturator prosthesis
Description: Prosthetic intervention with maxillary obturator prosthesis is necessary to restore the contours of the resected palate and to recreate the functional separation of the oral cavity and sinus and nasal cavities. Followings are the objectives of maxillary obturator Restoration of esthetics or cosmetic appearance of the patient, Restoration of function, Protection of tissues, Therapeutic or healing effect and psychological therapy.
Study: NCT05595447

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brentuximab Vedotin 50 MG [Adcetris]
Description: Brentuximab plus blocked PD-1 plus ASCT plus maintenance Brentuximab plus blocked PD-1
Study: NCT05394948

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary recommendations including experimental nutraceutic.
Description: Volunteers allocated in the control group will receive every day and during 3 consecutive weeks the experimental nutraceutic instead of the breakfast. Nutraceutical intake will be accompanied by nutritional advice to follow for the 3 weeks of intervention.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Dietary recommendations including control nutraceutic.
Description: Volunteers allocated in the control group will receive every day and during 3 consecutive weeks the control nutraceutic instead of the breakfast. Nutraceutical intake will be accompanied by nutritional advice to follow for the 3 weeks of intervention.
Study: NCT05141773

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Computed adenoma detection system (CADe) plus endocuff
Description: This is a computed system that helps the endoscopist to increase the detection of colorectal polyps. An add-on device (Endocuff) is also incorporated to the tip of the colonoscope

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Endocuff
Description: An add-on device (Endocuff) is also incorporated to the tip of the colonoscope
Study: NCT03767478

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Revitive Medic Coach (Actegy Ltd)
Description: Use the device for two 30-minute sessions per day, a minimum of five hours per week for 6 months at suprathreshold (2 x motor threshold).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Revitive Medic Coach (Actegy Ltd)
Description: Use the device for two 30-minute sessions per day, a minimum of five hours per week for 6 months at suprathreshold (2 x motor threshold).
Study: NCT05293795

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: 3D printed model
Description: Mother is given 3D printed model of fetus' face

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Mother is given a picture of 3D ultrasound of fetus
Study: NCT04725786

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: thoracic echography
Description: The research intervention corresponds to the performance of a thoracic echography to diagnose an incipient pulmonary interstitial syndrome.
Study: NCT04713800

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Monolithic zirconia screw retained implant-supported cantilever reconstruction supported by titanium base abutments, in a full digital workflow (ZR-TiB)
Description: In group ZR-TiB the implant impressions will be taken using an intra-oral scanner and the respective scanbody. The restorations will be manufactured by means of CAD/CAM procedures using monolithic zirconia. For sufficient aesthetics, the zirconia restorations can be manually veneered with veneering ceramic only at the buccal surface, while the occlusal surface will remain monolithic and will be high-gloss polished. The zirconia restorations will be extra-orally cemented onto titanium base abutments (Straumann® Variobase® for crown, Straumann AG), correctly polished and delivered to the patient, by screw-retention onto the implant.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: porcelain fused-to metal screw retained implant-supported cantilever reconstruction supported by a gold-abutment, in a conventional workflow (PFM-GA)
Description: In group PFM-GA implant impression will be taken using a polyvinyl siloxane or polyether impression material in a conventional manner with the use of stock trays and corresponding impression copings. The framework will be manufactured by the lost wax-technique using a gold-abutment (Straumann® Gold abutment for crown, Straumann AG) and a gold-alloy. All metal frameworks will be manually veneered with veneering ceramic, polished and glazed, and delivered to the patient, by screw-retention onto the implant.
Study: NCT06327581

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lactic Acid
Description: patients will be treated with MN combined with lactic acid solution 1%. Lactic acid solution 88% concentration PH (6.84), diluted with distilled water to have a final concentration of 1%
Study: NCT05284175

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orelabrutinib
Description: Orelabrutinib, orally, 50 mg QD
Study: NCT06327581

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: vit D
Description: patients will be treated with MN combined with topical application of vitamin D3 (an aqueous preparation of cholecalciferol (2.5 mg/ ml), The maximum total amount of vitamin D3 injected into a patient in every session will be 2.5 mg (1 ml)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone Acetonide
Description: patients will be treated with MN combined with triamcinolone acetonide injectable suspension (Epirelefan®, 40mg/ ml, Eipico, Egypt) (10 mg/ml) will be used in a dose of 0.1 ml/cm2 area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Saline
Description: patients will be treated with MN combined with normal saline 0.9%
Study: NCT06048679

Intervention type: DEVICE
Group type: OTHER
Intervention: Endovascular pulmonary artery flow-limiting covered stent implantation
Description: selective reduction of flow in the pulmonary arteries affected by anomalous pulmonary venous drainage using a modified flow-limiting covered stent
Study: NCT05446467

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: pembrolizumab+cisplatin + 5-FU
Description: ivgtt, pembrolizumab 200mg d1+cisplatin20 mg/m2 qd d1-d3 + 5-fluorouracil 3000mg/m2 last for 120hours, six circles. Subjects will undergo surgery after receiving neoadjuvant chemotherapy within 3 weeks, followed by adjuvant therapy and pembrolizumab alone maintenance treatment.
Study: NCT05271474

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ANNE ONE Platform
Description: ANNE ONE is one most advanced digital platforms that are gradually becoming more available to enable providers to help patients manage their condition. It integrates soft and flexible sensors for comprehensive vital signs monitoring. This platform creates objective transparency by automatically recording data from the sensor on the patient, lessening the need for patients to consciously track their COPD exacerbation events, enabling providers to proactively manage their patients' condition, and creating actionable reports for providers to review with their patients.
Study: NCT06495814

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 1/bag of Jinlida granules, 3 times/day, taken with hot water.
Description: All observation and intervention groups received lifestyle interventions, with only the intervention group of high-risk obese impaired glucose tolerance receiving intervention with Jinlida granules.
Study: NCT05329805

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: job crafting intervention
Description: the participated nurses will receive session about job crafting followed by activity related to job crafting
Study: NCT04601870

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No Financial Incentive
Description: No monetary incentive to participate in quit planning and quit counseling with a tobacco cessation specialist.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Financial Incentive (100 dollars)
Description: Financial incentive (100 dollars) to participate in quit planning and quit counseling with a tobacco cessation specialist.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Financial Incentive (50 dollars)
Description: Financial incentive (50 dollars) to participate in quit planning and quit counseling with a tobacco cessation specialist.
Study: NCT05686538

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: iDLI
Description: TCRab/CD19 depleted DLI 14 days after allogeneic stem cell transplantation. Targeted cell doses: \>10e7 NK cells/kg and \>10e6 TCRgd cells/kg
Study: NCT06013527

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Training
Description: Two different classes over alternate weeks twice per week :~1. 60-minute step aerobics class (Given week 1,3,5,7)~2. 60 minutes circuit training class (Given week 2,4,6,8)~Each class will include warm-up and cool-down periods both lasting 10-15 min. The exercise period of 30 minutes the maximum target RPE would be set at 14-16 on a 20-point BORG scale, a level of exercise that feels somewhat hard or hard and coincides with about 86-92% of maximal heart rate, 76-85% of maximal VO 2 and 5-7 metabolic equivalents (METs) ideal for improving the related domains of QoL and Cardiovascular endurance (12). During the first 3 weeks, the participants would exercise at a lower level of RPE (approximately 11-13), to adapt to the training and so that newly recruited participants could also join the group without difficulty.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Individually tailored home program
Description: The type of home training would mainly consist of endurance training such as walking, Nordic walking, or aerobic training, but it would also include jumps and leaps like step aerobics to promote bone health. The Participants will be asked to perform these thrice per week.
Study: NCT05810259

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Caravan Wellness app
Description: Caravan Wellness is a digital platform that offers brief mindfulness and light to moderate physical activity modules, among many others (e.g., Pilates, Yoga, Barre, meditation, etc.), to enhance overall individual well-being.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Caravan Wellness app
Description: Caravan Wellness is a digital platform that offers brief mindfulness and light to moderate physical activity modules, among many others (e.g., Pilates, Yoga, Barre, meditation, etc.), to enhance overall individual well-being.
Study: NCT04887779

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pathologist intervention
Description: viewing explanted organ and microscopy
Study: NCT04847232

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Zirconium Cyclosilicate (SZC)
Description: Powder for oral suspension in a sachet. A dose is titrated in 5 g increments during a period of 4 weeks from 5 g up to 15 g qd on non-dialysis days. Afterward, the dose is adjusted monthly (or more frequent based on clinical judgment) depending on the current potassium value as measured after the long interdialytic interval (LIDI).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SZC Placebo
Description: Powder for oral suspension in a sachet. A dose is titrated in 5 g increments during a period of 4 weeks from 5 g up to 15 g qd on non-dialysis days. Afterward, the dose is adjusted monthly (or more frequent based on clinical judgment) depending on the current potassium value as measured after the LIDI.
Study: NCT05762913

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Diaphragm Release Technique
Description: The therapist passes his fingers under the costal arch, during inspiration the therapist accompanies the movement of the ribs, while during expiration he takes his fingers deeper, increasing his pressure. The therapist progresses progressively deeper into the costal arch with each breath. The maneuver will be performed in two sets of 10 deep breaths. The diaphragm release technique will be applied in 3 sessions, with 2 days of rest in between.
Study: NCT04861792

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Michigan SPARC Quality Improvement Intervention
Description: Practice facilitation, electronic health record (EHR) support, performance monitoring and feedback combined with alcohol-related continuing medical education (CME) and maintenance of certification (MOC) and tools to support alcohol related care including a decision aid for shared decision making about alcohol use disorder (AUD).
Study: NCT06093334

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Low-field magnetic resonance imaging
Description: Imaging of lung parenchyma and function by LF-MRI

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Low-field magnetic resonance imaging
Description: Imaging of lung parenchyma and function by LF-MRI

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Low-field magnetic resonance imaging
Description: Imaging of lung parenchyma and function by LF-MRI

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cardiopulmonary testing
Description: Myocardial function (Strain-Analysis by echocardiography) and spiroergometry, capillary blood gases and lactate

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cardiopulmonary testing
Description: Myocardial function (Strain-Analysis by echocardiography) and spiroergometry, capillary blood gases and lactate

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cardiopulmonary testing
Description: Myocardial function (Strain-Analysis by echocardiography) and spiroergometry, capillary blood gases and lactate

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pulmonary testing
Description: Lung function (VC%, FEV1%)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pulmonary testing
Description: Lung function (VC%, FEV1%)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pulmonary testing
Description: Lung function (VC%, FEV1%)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Standard procedures/parameters routinely available in follow-up care after oncological treatment

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Standard procedures/parameters routinely available in follow-up care after oncological treatment

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Standard procedures/parameters routinely available in follow-up care after oncological treatment
Study: NCT05899998

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bright IDEAS
Description: Bright IDEAS® (Identify, Define, Evaluate, Act, See) is a problem-solving skills training program that was originally developed to alleviate distress in caregivers of children recently diagnosed with cancer. Intervention materials include instructor and user manuals, a brochure, and worksheets to be completed by the parent caregiver, initially with the help of the interventionist and then with increasing independence.