TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06236295

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508
Description: SHR6508 will be administered to all the eligible subjects
Study: NCT05242055

Intervention type: OTHER
Intervention: Integrated diagnosis and treatment for CKD
Description: This is an observational study. Investor will not intervene the clinical practice of doctors. In the real world, there would be many factors affect the proceeding of the guidelines contents. There will be integrated diagnosis and treatment during follow-up.

Intervention type: OTHER
Intervention: Integrated diagnosis and treatment for CKD
Description: This is an observational study. Investor will not intervene the clinical practice of doctors. In the real world, there would be many factors affect the proceeding of the guidelines contents. There will be integrated diagnosis and treatment during follow-up.
Study: NCT05687968

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 3D/AR MetaFood  nutrition education, and receive instant feedback from the nutritionists or AI after recording their dietary food image.
Description: The participants record diet images by using Taiwan FoodAPP and receive instant feedback from the nutritionists or AI after recording their dietary food image. The dietitian will use 3D/AR MetaFood food nutrition education platform to do nutrition education for patients.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: conventional nutrition education by dietitian
Description: The participants receive conventional health and nutrition education from state registered dietitian.
Study: NCT05066321

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Oriented Recovery Enhancement Sessions
Description: The MORE intervention will involve 8 weekly sessions (approximately 1 hour each), during which participants will be taught how to use mindfulness skills to regulate addiction severity, pain, and stress.
Study: NCT03271814

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: LPS
Description: 0.6 by/kg LPS single dose iv

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LPS
Description: 0.6 by/kg LPS single dose iv

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sterile Water
Study: NCT06388850

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Relationships Project
Description: The Healthy Relationships Project (HRP), created by the community-based organization Prevent Child Abuse Vermont (PCAVT), will be the focus of this rigorous evaluation study. The program is fully manualized with a widely accepted curriculum designed for Pre-K to 2nd graders (Care for Kids) and 3rd to 6th graders (We Care Elementary, though implementation will stop at 5th grade for this study). The HRP uses an upstream universal public health approach for the primary prevention of child and youth perpetration of child sexual abuse with developmentally appropriate intervention elements for children, faculty and staff at their schools, and for their caregivers.
Study: NCT06389981

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Veterans peer connect Program
Description: To assess outcomes of the Peer-led program, the study team will collect information from Veteran pilot test participants via surveys and data abstraction on healthcare utilization (Lung cancer screening completion, tobacco treatment) from the Veterans Affairs Corporate Data Warehouse. Survey data will be collected at 3 timepoints: baseline, post-Peer-led orientation, and 3-months post-enrollment. Healthcare utilization data will be abstracted from the corporate data warehouse to reflect the 3-month post-enrollment timepoint. Finally, interviews will be conducted with a subset of participants.
Study: NCT06256315

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hyper-ERAS Program
Description: Patients who met the inclusion criteria were treated with Hype-ERAS protocol, including preoperative education, intraoperative quality control, postoperative preventive analgesia, early ambulation, early recovery of diet, early removal of the drainage tube, urinary catheter, and gastric tube, and discharge within 48 hours or more than 48 hours safter surgery, and closely and standardized follow-up outside the hospital.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hyper-ERAS Program
Description: Patients who met the inclusion criteria were treated with Hype-ERAS protocol, including preoperative education, intraoperative quality control, postoperative preventive analgesia, early ambulation, early recovery of diet, early removal of the drainage tube, urinary catheter, and gastric tube, and discharge within 48 hours or more than 48 hours safter surgery, and closely and standardized follow-up outside the hospital.
Study: NCT05604495

Intervention type: DIAGNOSTIC_TEST
Intervention: Sweat Test
Description: In people with cystic fibrosis (CF), there is a problem in the transport of chloride across cell membranes. This results in higher concentrations of chloride (as salt) in sweat compared to those who do not have cystic fibrosis. So, if there is a family history or a possibility of CF, the sweat test is part of the special tests to help make, or exclude, a diagnosis of cystic fibrosis.
Study: NCT05069064

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: music
Description: In the music group, music that chosen by the participant will be played through a speaker by the nursing staff during outpatient hysteroscopy. Music will be played through a speaker instead of headphone in order to maintain a good communication and interaction between the participant and the doctor.

Intervention type: OTHER
Group type: OTHER
Intervention: no music
Description: Participants in the non-music group will undergo hysterosalpingography in the same setting and standard procedure without listening to any music.
Study: NCT05546164

Intervention type: OTHER
Intervention: Assessment of hand grip strength
Description: Assessment of hand grip strength

Intervention type: OTHER
Intervention: Assessment of hand grip strength
Description: Assessment of hand grip strength

Intervention type: OTHER
Intervention: Assessment of pinch strength
Description: Assessment of pinch strength

Intervention type: OTHER
Intervention: Assessment of pinch strength
Description: Assessment of pinch strength

Intervention type: OTHER
Intervention: Assessment of upper limb dexterity
Description: Assessment of upper limb dexterity

Intervention type: OTHER
Intervention: Assessment of upper limb dexterity
Description: Assessment of upper limb dexterity
Study: NCT04167748

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Preimplantation genetic testing for aneuploidy (PGT-A)
Description: 24-chromosome screening for aneuploidy in the preimplantation embryo (blastocyst stage)
Study: NCT06491056

Intervention type: DEVICE
Intervention: Focal Therapy for Prostate Cancer
Description: Ablation of \<75% of the prostate gland for limited volume prostate cancer
Study: NCT06473311

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: whole bady vibration and virtual reality
Description: study group I received a whole body vibration program in addition to a conventional physical therapy program, and study group II received a Wii-fit therapy program (a virtual reality treatment program) in addition to the same. A two-month treatment program was implemented for both groups. Every child in both groups had the same evaluation processes, which included using the Physical Self Maintenance Scale (PSMS) for daily living activities and a dynamometer to measure quadriceps muscular strength. Evaluation was done prior to the start of treatment and was done again after one month (post I) and two months (post II).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: whole bady vibration and virtual reality
Description: study group I received a whole body vibration program in addition to a conventional physical therapy program, and study group II received a Wii-fit therapy program (a virtual reality treatment program) in addition to the same. A two-month treatment program was implemented for both groups. Every child in both groups had the same evaluation processes, which included using the Physical Self Maintenance Scale (PSMS) for daily living activities and a dynamometer to measure quadriceps muscular strength. Evaluation was done prior to the start of treatment and was done again after one month (post I) and two months (post II).
Study: NCT06455592

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: practice adapted physical activity
Description: practice daily adapted physical activity during 4 days

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control arm
Description: practice once adapted physical activity during 4 days
Study: NCT06322836

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Duble current electro cardioversion
Description: Instead of the regular clinical treatment, in this study direct-current electrical cardioversion (DC-ECV) will be performed at the patient's home and will be carried out by well-trained and certified advanced practice providers (APP) on site, i.e. nurse practitioner or physician assistant, supported by an EMS ambulance team containing an ambulance nurse and ambulance driver, both trained advanced life-support (ALS) professionals.
Study: NCT05988268

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Vibration Foam Rolling
Description: The vibration foam rolling method will be applied to the gluteal, tensor fascia latae, hamstring, quadriceps femoris, and gastrocnemius muscles of both lower extremities of the participants in the Vibration Foam Rolling Group, in addition to the routine warm-up protocol, 3 days a week for a total of 15 minutes a day for 6 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Non-Vibration Foam Rolling
Description: The non-vibration foam rolling method will be applied to the gluteal, tensor fascia latae, hamstring, quadriceps femoris, and gastrocnemius muscles of both lower extremities of the participants in the Non-Vibration Foam Rolling Group, in addition to the routine warm-up protocol, 3 days a week for a total of 15 minutes a day for 6 weeks.
Study: NCT05863975

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human interferon alpha 2b vaginal Effervescent capsules
Description: ①Interferon group: human interferon alpha 2b vaginal effervescent capsule vaginal medication. ② Promestriene group: promestriene cream vaginal medication. ③Interferon + promestriene combination group: two drugs were given in combination.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human interferon alpha 2b vaginal Effervescent capsules
Description: ①Interferon group: human interferon alpha 2b vaginal effervescent capsule vaginal medication. ② Promestriene group: promestriene cream vaginal medication. ③Interferon + promestriene combination group: two drugs were given in combination.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human interferon alpha 2b vaginal Effervescent capsules
Description: ①Interferon group: human interferon alpha 2b vaginal effervescent capsule vaginal medication. ② Promestriene group: promestriene cream vaginal medication. ③Interferon + promestriene combination group: two drugs were given in combination.
Study: NCT05539729

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin
Description: A marketed antibiotic (Study Drug) supplied by Amerisource Bergen, by the Mount Sinai Investigational Drug Services (IDS), and encapsulated in red coating to match the placebo.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo created by the IDS and encapsulated in red coating to match the Study Drug.
Study: NCT06237543

Intervention type: OTHER
Intervention: hypotension
Description: MAP below 55 mmHg or long-term (2 minutes or more) hypotensive attacks will be treated with ephedrine 0.1mg/kg.
Study: NCT04450667

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nutricia PreOp
Description: Oral rehydration 2 hours before the scheduled cesarean section under spinal anesthesia
Study: NCT04811404

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethyl Eicosapentaenoic Acid
Description: Treatment will be for six weeks
Study: NCT06317818

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stem Cells
Description: Suspension of mesenchymal stromal cells for intratissular injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Comparative placebo
Description: Cell-free cell suspension solution devoid of cells for intratissular injection
Study: NCT06317675

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Osteopathic manipulative treatment (OMT)
Description: Manual therapy on different area of the body.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic manipulative treatment (OMT)
Description: Manual therapy on different area of the body.
Study: NCT06024395

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dental FearLess
Description: Dental FearLess is a self-administered CBT-based mobile app that takes approximately 1 hour to complete.
Study: NCT06091085

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetazolamide
Description: Administered for 3 nights, half-dose (1 pill) on the first night followed by full dose (2x250mg pills) for 2 nights

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo sugar pills administered for 3 nights, half-dose (1 pill) on the first night followed by full dose (2 pills) for 2 nights
Study: NCT04896047

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Meal test and muscle biopsies
Description: The FGF19 parameters will be assessed in fasting and in postprandial period after the consumption of a hyper-carbohydrate and hyper-lipidic test meal called Flexmeal.~A muscle biopsies by a needle will be performed before and after the Flexmeal.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Meal test and muscle biopsies
Description: The FGF19 parameters will be assessed in fasting and in postprandial period after the consumption of a hyper-carbohydrate and hyper-lipidic test meal called Flexmeal.~A muscle biopsies by a needle will be performed before and after the Flexmeal.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Meal test and muscle biopsies
Description: The FGF19 parameters will be assessed in fasting and in postprandial period after the consumption of a hyper-carbohydrate and hyper-lipidic test meal called Flexmeal.~A muscle biopsies by a needle will be performed before and after the Flexmeal.
Study: NCT06387654

Intervention type: BIOLOGICAL
Intervention: Blood sampling
Description: Blood will be taken in larger quantity

Intervention type: BIOLOGICAL
Intervention: Remainders of samples taken as part of the treatment
Description: blood, CSF, saliva, stools, urine, other biological fluids and tissue biopsies, hair follicles
Study: NCT04328246

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IES System
Description: The IES system is composed of a stimulator and self-adhesive surface gel electrodes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care Therapy
Description: Standard institutional practices for treating pressure injury.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Therapy
Description: Standard institutional practices for treating pressure injury.
Study: NCT06654414

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Treatment As Usual (ETAU)
Description: Brief counseling, the option of nicotine replacement therapy, and referral to the Quit Line.
Study: NCT06655649

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketone-IQ (1,3 Butanediol)
Description: Ketone-IQ (1,3 Butanediol) 20 or 40 g will be ingested (open-label) before bedtime.
Study: NCT05963958

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Active HD-tDCS
Description: Brain stimulation using active high definition transcranial direct current stimulation is applied simultaneously with the use of dexmedetomidine as a pharmacological treatment for delirium in critical illness patients with covid-19

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Sham HD-tDCS
Description: Sham high definition transcranial direct current stimulation is applied simultaneously with the use of dexmedetomidine as a pharmacological treatment for delirium in critical illness patients with covid-19
Study: NCT05003947

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AlloRx
Description: cultured allogeneic adult umbilical cord derived mesenchymal stem cells
Study: NCT06654583

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interactive Play Mat
Description: Use of developed interactive play mat that utilizes haptic feedback vibrations to assist children with delayed milestones in achieving Gross Motor Skills. The play mat aims to provide a therapeutic and engaging experience by incorporating visuals, sounds, and lights to encourage movement that might otherwise be challenging for these children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conventional Physical Therapy
Description: Stretching and Strengthening exercises
Study: NCT06595212

Intervention type: OTHER
Intervention: multiomic profile to assess genetic and environmental risk factiors
Description: Genomic, epigenetic, proteomic, microbiome, immunology, biomarker, metabolite, pesticide, metal, and metalloid investigations will be conducted. The twins will be followed longitudinally from a clinical perspective, with biological sample collections to assess discordance and identify early disease signatures in unaffected individuals.
Study: NCT04785170

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amino Acid
Description: A novel non-protein amino acid secreted by skeletal muscles which aids the cross-talk between skeletal muscles, liver, and adipose tissue at molecular levels. amino acid is generated by catabolism of the branched-chain amino acid valine. Existing literature states, amino acid induces body fat loss by increasing energy expenditure, stimulating free fatty acid (FFA) oxidation in the liver and skeletal muscle cell, and by enhancing oxygen consumption by adipose tissue and hepatocytes. It was observed that amino acid stimulated differentiation of energy storing white adipose tissue preadipocytes to an energy burning beige (brown to white) phenotype.
Study: NCT05244291

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Touch
Description: Therapeutic Touch will be applied to infants for 3 consecutive days, once a day, 10 minutes at any time during the day. There will be a four-day break. The Therapeutic Touch will be done a total of 3 times a week or 6 times in 2 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Touch
Description: Therapeutic Touch will be applied to infants for 3 consecutive days, once a day, 10 minutes at any time during the day. There will be a four-day break. The Therapeutic Touch will be done a total of 3 times a week or 6 times in 2 weeks.
Study: NCT04858763

Intervention type: OTHER
Intervention: No Intervention
Description: There will be no intervention during this study.

Intervention type: OTHER
Intervention: No Intervention
Description: There will be no intervention during this study.
Study: NCT06598150

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Shoulder Abduction
Description: Individuals will be visually cued to perform short, unilateral, isometric shoulder abduction tasks. A visual display will provide real-time feedback of the shoulder abduction torque, to help the participant target a predetermined torque level.
Study: NCT06603688

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: esomeprazole
Description: Esomeprazole 40mg, twice daily for 14 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: esomeprazole
Description: Esomeprazole 40mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bismuth
Description: Bismuth 220mg, twice daily for 14 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bismuth
Description: Bismuth 220mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: Amoxicillin 1000mg, twice daily for 14 days.
Study: NCT06275763

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase C: Eplerenone
Description: Participants randomly assigned to this arm take Eplerenone and placebos of Spironolactone and Torasemide

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase C: Spironolactone
Description: Participants randomly assigned to this arm take Spironolactone and placebos of Eplerenone and Torasemide

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase C: Torasemide
Description: Participants randomly assigned to this arm take Torasemide and placebos of Eplerenone and Spironolactone

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase B: Triplixam / Elestar HCT
Description: Replacement of ineffective antihypertensive treatment based on 3 or more antihypertensive drugs (single or dual drug preparations) with a triple single pill combination (SPC) based on optimally combined antihypertensive drugs: perindopril + indapamide + amlodipine (P+I+A) or olmesartan + hydrocholothiazide + amlodipine (O+H+A).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phase B: Triplixam / Elestar HCT
Description: Replacement of ineffective antihypertensive treatment based on 3 or more antihypertensive drugs (single or dual drug preparations) with a triple single pill combination (SPC) based on optimally combined antihypertensive drugs: perindopril + indapamide + amlodipine (P+I+A) or olmesartan + hydrocholothiazide + amlodipine (O+H+A).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase B: Triplixam / Elestar HCT
Description: Replacement of ineffective antihypertensive treatment based on 3 or more antihypertensive drugs (single or dual drug preparations) with a triple single pill combination (SPC) based on optimally combined antihypertensive drugs: perindopril + indapamide + amlodipine (P+I+A) or olmesartan + hydrocholothiazide + amlodipine (O+H+A).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase B: Triplixam / Elestar HCT
Description: Replacement of ineffective antihypertensive treatment based on 3 or more antihypertensive drugs (single or dual drug preparations) with a triple single pill combination (SPC) based on optimally combined antihypertensive drugs: perindopril + indapamide + amlodipine (P+I+A) or olmesartan + hydrocholothiazide + amlodipine (O+H+A).

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Phase A: Confirmation of uncontrolled hypertension
Description: Confirmation of the true ineffectiveness of antihypertensive therapy based on 3 or more antihypertensive drugs (single or dual drug preparations) using ABPM and home BP measurements.
Study: NCT05704894

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Erythropoietin
Description: Administration of Erythropoietin 150UI/Kg/week divided into 3 doses, IV, for a period of 12 weeks, in patients with hemoglobin between \<12g/dL