TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05623267

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sugemalimab
Description: Recombinant anti-PD-L1 fully human monoclonal antibody

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo of Sugemalimab
Study: NCT05955118

Intervention type: DEVICE
Intervention: Hydrus Microstent
Description: Hydrus Microstent placed at the time of cataract surgery
Study: NCT06133192

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Uvadex
Description: Uvadex use for ECP

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Steroids
Description: steroids 2 mg/kg/d
Study: NCT05972499

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: task-oriented training with pretend play
Description: Pretend play: Children engage in pretend play by acting out themes, taking on roles, assigning attributes to inanimate objects, and using objects as if they were something else Props will be added to hold the child interest. Role play costumes, or occupation props (police officer's suit), stimulate pretending elements.~Task-oriented training: It is involving the active, repetitive practice of functional activities to learn or relearn a motor skill. Training implies that the behavioral experiences are not just repetition of the same sensorimotor skill but involves progressive challenges to a participant's capabilities and involves tasks that are meaningful to the participant. It is based on the following principles: functional goal-directed training focus on practicing specific activities of importance to the child during daily activities; planning activity-focused interventions by adapting knowledge of motor learning ; and allowing for the interest and participation of the children.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: task-oriented training with pretend play
Description: Pretend play: Children engage in pretend play by acting out themes, taking on roles, assigning attributes to inanimate objects, and using objects as if they were something else Props will be added to hold the child interest. Role play costumes, or occupation props (police officer's suit), stimulate pretending elements.~Task-oriented training: It is involving the active, repetitive practice of functional activities to learn or relearn a motor skill. Training implies that the behavioral experiences are not just repetition of the same sensorimotor skill but involves progressive challenges to a participant's capabilities and involves tasks that are meaningful to the participant. It is based on the following principles: functional goal-directed training focus on practicing specific activities of importance to the child during daily activities; planning activity-focused interventions by adapting knowledge of motor learning ; and allowing for the interest and participation of the children.
Study: NCT04699409

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stroke educational campaign: FAST
Description: After randomization, study staff provided 15-minute education on the selected campaign to each individual participant using educational pictures.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stroke educational campaign: STROKE 112
Description: After randomization, study staff provided 15-minute education on the selected campaign to each individual participant using educational pictures.
Study: NCT05061979

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY1747846
Description: Solution for intravenous (IV) injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY1747846
Description: Solution for intravenous (IV) injection, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY1747846
Description: Solution for intravenous (IV) injection, single dose
Study: NCT06387914

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Stimulation ON
Description: Neurostimulation of the periaqueductal gray matter and sensory thalamus at a level with potential to provide pain relief

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Stimulation Pseudo-ON
Description: Neurostimulation of the periaqueductal gray matter and sensory thalamus S at a low level, not designed to provide pain relief
Study: NCT06165978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Report
Description: Daily or weekly reporting for therapists (messages)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social support
Description: Support meetings (in-person), parallel to educational sessions

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group activities
Description: Group activities (e.g., walking on familiar routes - parks, monumental areas, etc.)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: World Health Organization recommendations for being physically active
Description: World Health Organization's recommendations to maintain physical activity levels (i.e., 150-300 minutes/week of moderate to vigorous intensity physical activity; a weekly average of 10,000 steps/day or 100-120 minutes walking, which implies maintaining a pace of 100 steps/minute - corresponding to the average cadence across different age and gender groups).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: World Health Organization recommendations for being physically active
Description: World Health Organization's recommendations to maintain physical activity levels (i.e., 150-300 minutes/week of moderate to vigorous intensity physical activity; a weekly average of 10,000 steps/day or 100-120 minutes walking, which implies maintaining a pace of 100 steps/minute - corresponding to the average cadence across different age and gender groups).
Study: NCT04693637

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Posoleucel (ALVR105)
Description: Administered as 2-4 milliliter infusion
Study: NCT06231667

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: four training sessions were applied to the intervention group
Study: NCT04657003

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study: NCT06337942

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bladder Transplantation
Description: A bladder transplantation will be performed. The bladder will be recovered from a brain-dead human donor. The connections that will be made will include connections between donor and recipient blood vessels, the bladder transplant and the recipient urethra, and the recipient's ureter(s) to the new bladder.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combined Kidney and Bladder Transplantation
Description: For patients who qualify for a combined kidney and bladder transplant, both a kidney and a bladder transplant will be performed. Both kidney and bladder allografts will be recovered from the same brain-dead human donor. The connections that will be made will include connections between donor and recipient blood vessels, the bladder transplant and the recipient urethra, and the kidney transplant ureter to the transplanted bladder. If the recipient has continued urine output, new connections between the native ureters and the transplanted bladder will also be made.
Study: NCT04838678

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neuropeptide Y
Description: intra-arterial infusion of neuropeptide Y
Study: NCT06280885

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Behaviour Change (Pedometer)
Description: Participants in both arms will be provided with a pedometer as a health behaviour change intervention
Study: NCT06496776

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Choukroun's technique
Description: Suturing will be done using the method described by Choukroun.
Study: NCT04716517

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alkasite bioactive restorative material.
Description: Alkasite restorative is a category of filling material, like compomer, and is essentially a subgroup~of the composite resin. Cention N is a urethane dimethacrylate (UDMA)-based, self-curing powder/liquid restorative with optional additional light curing. The liquid comprises of dimethacrylates and initiators, while the powder contains various glass fillers, initiators, and pigments. It is radio opaque and contains alkaline glass fillers capable of releasing fluoride, calcium, and hydroxide ions. Due to the sole use of cross-linking methacrylate monomers in combination with a stable, efficient self-cure initiator, Cention N displays a high polymer network density and degree of polymerization over the complete depth of the restoration.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resin Modified Glass Ionomer
Description: The resin-modified glass ionomer materials are hybrid materials of traditional glass ionomer cement with a small addition of light-curing resin, and hence exhibit properties intermediate to the two, with some characteristics superior to conventional glass ionomer materials
Study: NCT05369481

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sildenafil 2%
Description: Patients with male androgenic alopecia will be given topical Sildenafil 2% to apply twice daily for 6 consecutive months and then follow up.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Minoxidil 5 %
Description: Patients with male androgenic alopecia will be given topical Minoxidil 5 % to apply twice daily for 6 consecutive months and then follow up.
Study: NCT06377891

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Emotional Resilience training
Description: Primiparous pregnant women in the experimental group will be given emotional resilience training in the last trimester.
Study: NCT05771207

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: soy protein
Description: The intervention is made up of soy protein supplements (30g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: whey protein
Description: The intervention is made up of whey protein supplements (30g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: The intervention is made up of maltodextrin (30g/d) and dietary pattern modification.
Study: NCT04919954

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tebipenem Pivoxil Hydrobromide
Description: Tebipenem 300 mg or 600 mg will be administered orally every 8 hours for total of 3 to 7 doses

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tebipenem Pivoxil Hydrobromide
Description: Tebipenem 300 mg or 600 mg will be administered orally every 8 hours for total of 3 to 7 doses
Study: NCT04943120

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Snow-plow technique
Description: In class II cavities, application of X-tra Base bulk fill flowable composite (VOCO) in 1 mm thickness without curing followed by X-tra Fill bulk fill packable composite (VOCO) to restore the proximal wall. Polymerization as one unit for 20 seconds.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bulk fill technique
Description: In class II cavities, application of 4 mm increment of X-tra Fill bulk fill packable composite (VOCO) to restore the proximal wall. then the restoration id fully polymerized.
Study: NCT04838678

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neuropeptide Y
Description: intra-arterial infusion of neuropeptide Y

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neuropeptide Y
Description: intra-arterial infusion of neuropeptide Y

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neuropeptide Y
Description: intra-arterial infusion of neuropeptide Y
Study: NCT06376942

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glycopyrronium
Description: Nebulized glycopyrronium 50 mcg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ipratropium
Description: Nebulized iptratropium 500 mcg

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: 0.9% saline 2 ml
Study: NCT05891457

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nutritional Intervention
Description: * Severe acute malnourished children were provided with appropriate nutritional therapy/treatment that include supplementation of a high-calorie diet; i.e., F-100 milk and khichuri-halwa for nutritional rehabilitation.~* Egg milk and micronutrient supplementation for recovery from severe stunting following standard guidelines for facility based management and recently conducted community based nutrition intervention studies.~* Wasted children were treated with suitable local nutritional management (NM), such as infant and young child feeding practices (IYCF), providing MNP and nutrition education.
Study: NCT04778111

Intervention type: OTHER
Intervention: Measurement of the actual and perceived maximum reachable distance
Description: A device (a table) will present luminous targets (green circles) to the subjects. Subjects will be asked to determine whether or not they are able to reach this target with their upper limb.

Intervention type: OTHER
Intervention: Measurement of the actual and perceived maximum reachable distance
Description: A device (a table) will present luminous targets (green circles) to the subjects. Subjects will be asked to determine whether or not they are able to reach this target with their upper limb.
Study: NCT05723211

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vinyasa yoga group
Description: Participants will be instructed to perform a pre-recorded 60-minute vinyasa yoga session 3 times a week for 4 weeks.

Intervention type: OTHER
Group type: OTHER
Intervention: Non-active control group
Description: Participants will be instructed to sit quietly for 60 minutes and watch a nature documentary during this time. The participants will be asked to maintain their current lifestyle habits and refrain from starting a new exercise and/or yoga program.
Study: NCT04772651

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean Diet
Description: Diet meeting the requirements for mediterranean style (rich in vegetables, fruit, olive oil, fish) (Davis et al., 2015)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal hospital diet
Description: Normal hospital diet
Study: NCT05779696

Intervention type: OTHER
Intervention: No-intervention
Description: This is a non-intervention study.
Study: NCT05271045

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: fortified canola oil with vitamins A and D and γ-oryzanol
Description: 30 g fortified canola oil with vitamins A and D and γ-oryzanol

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Active comparator
Description: 30 g fortified canola oil with vitamins A and D

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 30 g fortified sunflower oil with vitamins A and D
Study: NCT04836871

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: DFPP combined with chemotherapy
Description: Double filtration plasmapheresis combined with chemotherapy
Study: NCT03422705

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optimised programming
Description: Optimised programming to avoid RV pacing when possible.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optimised programming
Description: Optimised programming to avoid RV pacing when possible.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lisinopril
Description: Uptitration of lisinopril

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: No pacemaker adjustment or medical therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: No pacemaker adjustment or medical therapy

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard care
Description: No pacemaker adjustment or medical therapy
Study: NCT06104358

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HU6
Description: HU6 is being evaluated for its effect on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: HU6
Description: HU6 is being evaluated for its effect on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function
Study: NCT05832970

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Brief skin cooling
Description: Brief skin cooling will be applied to the hand using the cold-bath immersion
Study: NCT05637944

Intervention type: PROCEDURE
Intervention: oro tracheal intubation
Description: chest trauma requiring oro tracheal intubation
Study: NCT06497296

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lidocaine
Description: Lidocaine spray in both group with same puff number, but the timing before EGD insertion is different

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine
Description: Lidocaine spray in both group with same puff number, but the timing before EGD insertion is different
Study: NCT05416307

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ELA026
Description: Single or multiple daily doses of ELA026
Study: NCT05091515

Intervention type: OTHER
Intervention: Personal protective equipment from biological hazard
Description: Includes: isolation clothing, mask, eyewear, overshoes
Study: NCT05481047

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HPI
Description: based on HPI values, clinicians will administer drugs or fluids in order to avoid arterial hypotension
Study: NCT04901091

Intervention type: OTHER
Intervention: Not Provided
Description: Not Provided

Intervention type: OTHER
Intervention: Not Provided
Description: Not Provided

Intervention type: OTHER
Intervention: Not Provided
Description: Not Provided
Study: NCT05583760

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Experimental: Osteopathic manipulation TUG for scaphoid bone
Description: The sequence of execution of the scaphoid TUG technique shall be applied as follows. Patient in the supine position. The inner hand of the intervener makes contact with the pisiform through the hypothenar eminence and ulnar border of the hand over the scaphoid tubercle, the outer hand reinforces the contact. The thumbs are directed to the sole of the patient's foot. The parameters are sought by bringing the sole of the foot into eversion, thus bringing the scaphoid into internal rotation (the direction of correction). In order to reduce the slack, the operator drops his body weight backwards while increasing the internal rotation parameter of the scaphoid. The manipulation is performed by associating a rapid traction movement with an increase of the correction parameter towards the internal rotation of the scaphoid.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham group: Sham osteopathic manipulation TUG for scaphoid bone
Description: The intervention will be performed in the same way as the intervention group, without actually performing the TUG manipulation on the scaphoid bone, only placing it in tension.
Study: NCT05463991

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bioengineered collagen implant
Description: Urethral stricture repair
Study: NCT05974813

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: L-Citrulline
Description: 6 g (3 g every 12 h) of L-citrulline for six days

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 6 g (3 g every 12 h) of maltodextrin for six days
Study: NCT06368908

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Functional Magnetic Muscle Stimulation
Description: Peripheral neuromuscular system stimulation will be conducted for the quadriceps femoris muscle using a magnetic stimulator (Tesla stym, Iskra Medical, Otoče, SLO). For magnetic stimulation, we will use pulse trains (20-50 Hz) with intensities ranging from 0.5 to 2.5 Tesla. The stimulation trains will be up to 3-6 seconds long, and the duty cycle will be varied from 1:1 to 1:10. Muscles will be stimulated with a magnetic field intensity that triggers visible contraction. The stimulation will last for 55 minutes per selected limb and will be performed 5 days a week.
Study: NCT05749393

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Heparin sodium
Description: Intravenous heparin was administered during intracranial aneurysm embolization with a guide catheter and discontinued at the end of the procedure.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Heparin sodium
Description: Intravenous heparin was administered during intracranial aneurysm embolization with a guide catheter and discontinued at the end of the procedure.
Study: NCT05327361

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liftactiv B3
Description: Participants will apply a dime size amount of the serum to 1 side of the face.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sunscreen
Description: Participants will apply a dime size amount of sunscreen to cover the other half of the face.
Study: NCT03996317

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Room air
Description: Avoidance of hyperoxygenation
Study: NCT04372459

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online integrated and stepped psychosocial care
Description: This program features four levels of care, increasing in intensity of psychosocial care as patients move from one level to the next one.~Step 1: Screening and monitoring of several psychosocial variables through the central mobile application of the program (App ICOnnecta't).~Step 2: Online guided and self-help psychoeducation Campus in which patients can consult videos and online resources, co-constructed between health professionals and patients, containing reliable and rigorous information related to the oncological process.~Step 3: Online community of psychosocial support. Participants can choose from 12 cancer-related discussion forums and share with the community any health-related question that worries them fostering, thus, debate and stimulating peer-support.~Step 4: Intensive online group psychotherapy (App ICOnnecta't Videoconsultation), based on the Group Positive Psychotherapy program for cancer survivors (Ochoa, Sumalla, Maté, Castejón, Rodríguez et al., 2010).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual psychosocial care
Description: This active control group will receive the standard psychosocial treatment for cancer survivors in the participating centers, led by a clinical psychologist and consisting of 8 individual, 45/60-minute sessions, each of which every 1-2 months, focused on providing emotional support and psychoeducation during the first year of primary cancer treatment.
Study: NCT06103578

Intervention type: DIAGNOSTIC_TEST
Intervention: GCF and saliva analysis
Description: ELISA

Intervention type: DIAGNOSTIC_TEST
Intervention: GCF and saliva analysis
Description: ELISA

Intervention type: DIAGNOSTIC_TEST
Intervention: GCF and saliva analysis
Description: ELISA