TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05049005

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Simplified dietary tracking
Description: Mobile-delivered nutrition program using simplified dietary monitoring with a focus on weight loss.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Simplified dietary tracking
Description: Mobile-delivered nutrition program using simplified dietary monitoring with a focus on weight loss.
Study: NCT06069388

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: diaphragm technique
Description: The patient will be placed in a supine position with knees bent on a cushion. The therapist will position himself oriented from the patient's head towards his feet. The therapist will make contact with the ulnar edge of his hands on the lower edge of the last ribs. It will be pulled cephalad during the inspiratory time, opening the rib cage laterally. Traction will be maintained during expiratory time and repeated during a cycle of 10 breaths.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: conventional therapy
Description: The patient will be placed in a supine position with knees bent on a cushion. The therapist will position himself oriented from the patient's head towards his feet. The therapist will make contact with the ulnar edge of his hands on the lower edge of the last ribs. It will be pulled cephalad during the inspiratory time, opening the rib cage laterally. Traction will be maintained during expiratory time and repeated during a cycle of 10 breaths.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: The patient will be placed in a supine position with knees bent on a cushion. The therapist will position himself oriented from the patient's head towards his feet. The therapist will make contact with the ulnar edge of his hands on the lower edge of the last ribs. It will be pulled cephalad during the inspiratory time, opening the rib cage laterally. Traction will be maintained during expiratory time and repeated during a cycle of 10 breaths.
Study: NCT05252858

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: nCAP Signal Relief Patch
Description: nCAP Signal Relief Patch post-operatively applied to the subject's surgical dressing by a trained researcher in the immediate Post Anesthesia Care Unit (PACU)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Subjects will undergo surgery using the approved ERAS anesthetic and post-operative pain management protocols. At Shadyside Hospital, the ERAS Protocol for these subjects involves preoperative meloxicam 15mg PO, gabapentin 300mg PO, acetaminophen 1g PO. Intra-operative, patients receive a spinal block (bupivacaine) and propofol IV sedation. Postoperative pain medication is titrated to the individual patient's level of pain (0-10). 0.2 mg IV hydromorphone can be given for breakthrough pain, oxycodone 5mg PO for moderate pain (4-6) and oxycodone 10 mg PO for severe pain (7-10). Ketorolac 15 mg IV is given Q6H during the hospital stay. Discharge medication may be Norco 5-325mg as prescribed by the surgeon.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Subjects will undergo surgery using the approved ERAS anesthetic and post-operative pain management protocols. At Shadyside Hospital, the ERAS Protocol for these subjects involves preoperative meloxicam 15mg PO, gabapentin 300mg PO, acetaminophen 1g PO. Intra-operative, patients receive a spinal block (bupivacaine) and propofol IV sedation. Postoperative pain medication is titrated to the individual patient's level of pain (0-10). 0.2 mg IV hydromorphone can be given for breakthrough pain, oxycodone 5mg PO for moderate pain (4-6) and oxycodone 10 mg PO for severe pain (7-10). Ketorolac 15 mg IV is given Q6H during the hospital stay. Discharge medication may be Norco 5-325mg as prescribed by the surgeon.
Study: NCT05310877

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Values-Affirmation
Description: Participants will engage in a brief values-affirmation exercise to target personal motivation and openness to medication adherence. The interventionist will then review tailored medication education and individual skills training recommendations. Following the intervention session, participants will receive electronic pill box(es) that are labeled with the participants' most important core value(s) and will be asked to use these pill box(es) to take their HF medications for 4 weeks.
Study: NCT04626323

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Roux-en-Y gastric bypass
Description: 1. Pneumoperitoneum closed with Veress needle~2. Identification of Treitz angle~3. Measurement of biliary loop (50 cm)~4. Bowel transection with linear stapler (white load)~5. Measurement of the alimentary limb (100 cm)~6. Laterolateral Entero-anastomoses (white load)~7. Construction of gastric pouch distant about 3 cm from the esophageal-gastric junction with stomach section in the small curvature.~8. Linear cutting anastomosis (gastrojejunostomy) from about 1 to 1.2 cm~9. Anastomosis integrity evaluation by methylene blue test and/or perioperative air.~Expected surgical time: 60 minutes

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Best medical treatment
Description: Patients will also receive standard of care medical therapy for DKD (ACEI or ARB + SGLT2i) and T2DM (metformin, glitazones, incretin therapy - DPP4 inhibitor and GLP-1 analogs - and insulin, if necessary).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Best medical treatment
Description: Patients will also receive standard of care medical therapy for DKD (ACEI or ARB + SGLT2i) and T2DM (metformin, glitazones, incretin therapy - DPP4 inhibitor and GLP-1 analogs - and insulin, if necessary).
Study: NCT05314309

Intervention type: DIAGNOSTIC_TEST
Intervention: Comparison of two tests (FIT and mtFIT) in the same bowel movement
Description: Invitees for the Dutch National CRC screening program will be randomly selected by the Screening Organization and invited to participate in this study, where next to the current FIT, participants will also perform the mtFIT in one bowel movement. Both tests will be analysed and if one of the two test results is positive, the individual will be referred for colonoscopy.
Study: NCT05285111

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reconnecting to Internal Sensations and Experiences
Description: The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional awareness, and understanding the self in relation to others.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Habits
Description: The comparator condition is called Health Habits and is matched for time and attention; participants complete modules related to healthy habits such as financial planning, hygiene, stretching, and healthy eating.
Study: NCT05285839

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupixent
Description: dupilumab 300mg
Study: NCT04811196

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Selinexor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Selinexor
Study: NCT05433610

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-invasive Ventilation
Description: Exercise capacity testing using the device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-invasive Ventilation
Description: Exercise capacity testing using the device

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Non-invasive Ventilation
Description: Exercise capacity testing using the device
Study: NCT04689542

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sit-To-Stand test
Description: The 1-minute sit-to-stand test will be realized with or without a surgical facemask covering the face of the patient with COVID-19
Study: NCT06550908

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lutetia Training Plattform
Description: Training platform Lutetia offers training the Paris classification using real or artificial images of colon polyps.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lutetia Training Plattform
Description: Training platform Lutetia offers training the Paris classification using real or artificial images of colon polyps.
Study: NCT06432387

Intervention type: OTHER
Intervention: Patients undergoing complex thoraco-abdominal aortic aneurysm repair
Description: Patients undergoing complex thoraco-abdominal aortic aneurysm repair
Study: NCT04748718

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise-based injury prevention program
Description: \~10-minute, 4+ times/week exercise-based injury prevention program. Includes flexibility, strengthening, balance, agility and plyometric exercises.
Study: NCT06026436

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood samples
Description: 12-24 hours after P2Y12 ADP receptor loading dose (LD)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood samples
Description: 1 month after Percutaneous Coronary Intervention (PCI)
Study: NCT04927910

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ture self-acupressure
Description: 8-week intervention of self-acupressure on acupoints

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham self-acupressure
Description: 8-week intervention of self-acupressure on non-acupoints

Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: routine care by hospitals
Study: NCT04716244

Intervention type: OTHER
Intervention: interview/focus group/questionnaire
Description: Prior to the meetings, participants will be asked to fill in a questionnaire with demographic data including age, family status, number of pregnancies, number of children, education, and employment, history of preeclampsia or GDM, family history of CVD, and self-reported height and weight We will conduct up to 8 groups or until we reach saturation of themes. For the teleconference focus groups, the number of participants will be limited to 6 women per group, as recommended from previous research on teleconference focus groups51. The face to face focus groups will include up to -12 women. The expected duration of each group, will last 1-2 hours.~We will conduct up to 36 in-depth interviews. The expected duration of each interview will last 30 minutes to -1.5 hours.~Participants will be asked for their consent to record the meetings, audio only. The discussions will be then transcribed. An interview guide will be followed.

Intervention type: OTHER
Intervention: interview/focus group/questionnaire
Description: Prior to the meetings, participants will be asked to fill in a questionnaire with demographic data including age, family status, number of pregnancies, number of children, education, and employment, history of preeclampsia or GDM, family history of CVD, and self-reported height and weight We will conduct up to 8 groups or until we reach saturation of themes. For the teleconference focus groups, the number of participants will be limited to 6 women per group, as recommended from previous research on teleconference focus groups51. The face to face focus groups will include up to -12 women. The expected duration of each group, will last 1-2 hours.~We will conduct up to 36 in-depth interviews. The expected duration of each interview will last 30 minutes to -1.5 hours.~Participants will be asked for their consent to record the meetings, audio only. The discussions will be then transcribed. An interview guide will be followed.
Study: NCT05719181

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: rhBMP-2
Description: Recombinant Human Bone Morphogenetic Protein-2 with an Absorbable Collagen Sponge .
Study: NCT05482802

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: An active training tool on weight bias and knowledge about obesity
Description: The intervention will take place at the university simulation center and include three components. First, a short lecture on obesity and weight bias. Second, four scenarios that simulate meetings between health professionals and people with obesity which will be presented by professional role-players in sequence. Each scenario will include a different therapeutic situation and include varying degrees of weight bias, stigma, and discrimination to stimulate students to think and react. Third, an active open discourse with a person with obesity will be held.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: A short-written document on obesity
Description: A short-written document on obesity which will be based on current literature.
Study: NCT06450769

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aronia juice
Description: 100% aronia juice, 100 mL/day, twelve-week follow-up

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aronia juice
Description: 100% aronia juice, 100 mL/day, twelve-week follow-up

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: An individually planned nutrition program suitable for the energy-restricted Mediterranean diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: An individually planned nutrition program suitable for the energy-restricted Mediterranean diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-fat diet
Description: An individually planned nutrition program suitable for the energy-restricted low-fat diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-fat diet
Description: An individually planned nutrition program suitable for the energy-restricted low-fat diet
Study: NCT05890079

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Subcostal transversus abdominis plane block
Description: External oblique intercostal plane block will be administered at the end of the surgery and after skin closure.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: External oblique intercostal plane block
Description: External oblique intercostal plane block will be administered at the end of the surgery and after skin closure. .
Study: NCT05580016

Intervention type: DIAGNOSTIC_TEST
Intervention: Soluble Urokinase Plasminogen Activation Receptor measurement
Description: In addition to the standard of care, Soluble Urokinase Plasminogen Activation Receptor levels will be measured in patients.
Study: NCT05885932

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Drug-eluting stenting plus aspirin and clopidogrel or ticagrelor
Description: All the participants in this group will be performed with extracranial vertebral artery sirolimus-eluting stenting plus medical therapy including aspirin 100mg per day + clopidogrel 75mg per day or ticagrelor 90mg twice per day for 6 months and mono anti-platelet therapy thereafter.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin and clopidogrel or ticagrelor
Description: All the participants in this group will be given medical therapy including aspirin 100mg per day + clopidogrel 75mg per day or ticagrelor 90mg twice per day for 6 months and mono anti-platelet therapy thereafter.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mono anti-platelet therapy
Description: mono anti-platelet therapy
Study: NCT05379920

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High Volume Aerobic Exercise
Description: Aerobic exercise is completed for 30 minutes, 5 days a week. Exercise intensity is adjusted weekly to 90% of the heart rate threshold. Exercise interventions for all participants are adjusted to the 90% Heart rate threshold (HRt) collected on the BCTT.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: High Volume Aerobic Exercise
Description: Aerobic exercise is completed for 30 minutes, 5 days a week. Exercise intensity is adjusted weekly to 90% of the heart rate threshold. Exercise interventions for all participants are adjusted to the 90% Heart rate threshold (HRt) collected on the BCTT.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low Volume Aerobic Exercise
Description: Aerobic exercise is completed for 20 minutes, 3 days a week. Exercise intensity is adjusted weekly to 90% of the heart rate threshold. Exercise interventions for all participants are adjusted to the 90% Heart rate threshold (HRt) collected on the BCTT.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Low Volume Aerobic Exercise
Description: Aerobic exercise is completed for 20 minutes, 3 days a week. Exercise intensity is adjusted weekly to 90% of the heart rate threshold. Exercise interventions for all participants are adjusted to the 90% Heart rate threshold (HRt) collected on the BCTT.
Study: NCT04741048

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CI624 Slim 20 Electrode
Description: Cochlear Ltd CI624 cochlear implant with Slim 20 Electrode
Study: NCT05374096

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient-Chosen Music
Description: Music played into headphones.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Silence into headphones.
Study: NCT06411652

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reflexology
Description: 1. First, the patient's foot will be cleaned with cotton dipped in warm water,~2. In order not to disturb the patient, the hands will be warmed and one or two ccs of baby oil will be used to facilitate the massage.~3. Before applying the main technique, the first two minutes of each session will be spent using the relaxation technique, which involves back and forth movements with the palm of the palm on the outer edge of the foot, from the outer part of the ankle to the little toe, to relieve muscle tension and spasm.~4. Then, alternate pressure will be applied to the reflex points of the right thumb by taking the heel of one foot in the left hand.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Touch
Description: 1. The procedure will be explained to the woman,~2. The procedure will be performed in the patient's bed.~3. The practitioner will center by making his body, mind and emotions quiet and focused, prepare himself for the practice and remain centered throughout the intervention,~4. There will be good intentions to help the woman get treatment,~5. In order to scan the energy field, the patient's entire body will be held with the palms of the practitioner's hands facing the patient, it will be moved with a soft movement from
Study: NCT05664906

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chinese Medicine Oral Rinse Formula-I (CMORF-I)
Description: * Prescription of Chinese Medicine Oral Rinse Formula-I (CMORF-I)~* Instruction to rinse:~  1. The above amount of concentrated CM granules will be divided and packed in 4 bags per day.~ 2. Dissolve 1 bag of concentrated CM granules with 150ml 80'C boiled hot water, and wait for 20 mins to cool down.~ 3. Clean the mouth thoughtfully by rinsing with 150ml of distilled water for 2 minutes.~ 4. Rinse the mouth thoughtfully with one-third of the dissolved and cooled CM oral rinse, gargle, expel after 3 minutes, do not swallow and repeat twice.~ 5. To ensure better contact of the CM oral rinse in all parts and folds of the oral cavity, our research assistant and CMP will guide the patients to fully agitate the mouth, use the tongue to stir repeatedly among the teeth, cheeks and palate surface, and to raise the tip of the tongue for a moment and tilt the head back.~ 6. 4 times a day (half an hour after every meal, half an hour before sleep), from baseline to 2 weeks after RT.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard Care
Description: • Standard care including normal saline or medical mouthwash, optional analgesics and antibiotics will be offered by hospital.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care
Description: • Standard care including normal saline or medical mouthwash, optional analgesics and antibiotics will be offered by hospital.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo granules, instruction is the same as CMORF-I.
Study: NCT05185804

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dimolegin
Description: 60 mg orally, 1 time per day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clexane
Description: 40 mg subcutaneously, 1 time per day
Study: NCT05722691

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Double-Stranded RNA sodium salt
Description: Once intramuscular injection 5 mg (1 vial)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Once intramuscular injection (1 vial)
Study: NCT06270641

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ExerciseRx intervention
Description: ExerciseRx is a cloud-based, HIPPA-compliant free software platform created for healthcare providers to prescribe and monitor physical activity as part of routine care. ExerciseRx translates clinically relevant activity data collected by the patient's existing personal smart devices (Android or iOS phone) into actionable metrics on a dashboard within the Epic electronic health record. Providers then use the platform to prescribe physical activity tailored to patients' ability levels and preferences. The platform incorporates behavior change strategies, including motivational feedback and nudges. It also facilitates a feedback loop with the provider, fostering caring patient-provider connections around activity promotion and behavior change. ExerciseRx leverages patients' personal smartphone capabilities to track, quantify, and tailor personalized physical activity solutions, which makes it more readily scalable as a solution across diverse patient populations.
Study: NCT06249230

Intervention type: DIAGNOSTIC_TEST
Intervention: Hematologic features
Description: Hematologic features include coagulation indicators, autoimmune indicators, and endocrine indicators.

Intervention type: DIAGNOSTIC_TEST
Intervention: Hematologic features
Description: Hematologic features include coagulation indicators, autoimmune indicators, and endocrine indicators.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound indices of uterine artery blood flow
Description: Ultrasound indices of uterine artery blood flow include endometrial thickness, endometrial artery blood flow parameters , and bilateral uterine artery blood flow parameters.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound indices of uterine artery blood flow
Description: Ultrasound indices of uterine artery blood flow include endometrial thickness, endometrial artery blood flow parameters , and bilateral uterine artery blood flow parameters.

Intervention type: OTHER
Intervention: Demographic characteristics
Description: Demographic characteristics include age, the number of previous spontaneous abortions (including biochemical pregnancies), BMI, fertility history, past disease history, chromosomal status, family and genetic history, etc.

Intervention type: OTHER
Intervention: Demographic characteristics
Description: Demographic characteristics include age, the number of previous spontaneous abortions (including biochemical pregnancies), BMI, fertility history, past disease history, chromosomal status, family and genetic history, etc.