TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05825638

Intervention type: OTHER
Intervention: Continuous training session
Description: Continuous training consists of a 5 minute warm up, 5 minute cool down and 20 minutes of moderate intensity work. The workload is set at 60% of the patient's maximum power

Intervention type: OTHER
Intervention: Interval training session
Description: Interval training consists of a 5-minute warm-up, a 5-minute cool-down and 20 minutes of alternating 60 seconds of high-intensity work (100% of the maximum power recorded in the incremental test that was carried out when the patient was admitted to the pulmonary rehabilitation department) and 60 seconds of unloaded pedalling or rest.
Study: NCT03644641

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Desflurane Group
Description: General anesthesia will be held using desflurane in end- tidal concentration according to target value of entropy levels (between 40 and 60).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Propofol Group
Description: General anesthesia will be held using Schnider effect model for propofol (target control anesthesia). Titration will be done according to target value of entropy levels (between 40 and 60).
Study: NCT06347224

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Virtual placement of lag screws in both columns of the acetabulum on 3D pelvic CT models.
Description: The intervention aims to simulate a percutaneous fixation technique that could be applied in a real surgical environment, offering insights into the potential for personalized surgical planning and optimization of outcomes for patients with acetabular fractures. This virtual approach allows for the exploration of various screw placement strategies without the ethical and practical constraints of direct clinical experimentation.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Virtual placement of lag screws in both columns of the acetabulum on 3D pelvic CT models.
Description: The intervention aims to simulate a percutaneous fixation technique that could be applied in a real surgical environment, offering insights into the potential for personalized surgical planning and optimization of outcomes for patients with acetabular fractures. This virtual approach allows for the exploration of various screw placement strategies without the ethical and practical constraints of direct clinical experimentation.
Study: NCT05349890

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TCR-transduced T cells
Description: TSA-reactive TCR-engineered T cells

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CDX-1140
Description: Recombinant fully human IgG2κ monoclonal antibody

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Humanized immunoglobulin G4 (IgG4) monoclonal antibody
Study: NCT05290259

Intervention type: OTHER
Intervention: Ballroom Dance
Description: The Ballroom Basics for Balance Program is a dance focused exercise program developed by a Physical Therapist in the Madison area.
Study: NCT05156723

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Subunit recombinant vaccine for the prevention of coronavirus infection
Description: solution for intramuscular injection, 0.5 ml

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Subunit recombinant vaccine for the prevention of coronavirus infection
Description: solution for intramuscular injection, 0.5 ml

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Subunit recombinant vaccine for the prevention of coronavirus infection
Description: solution for intramuscular injection, 0.5 ml

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Subunit recombinant vaccine for the prevention of coronavirus infection
Description: solution for intramuscular injection, 0.5 ml

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: solution for intramuscular injection, 0.5 ml
Study: NCT06416215

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychological intervention based on WBT and cognitive restructuring
Description: Participants will engage in 6 weekly group session of two hours. One part will be held by a trained dietician and will focus on nutritional education, particularly emphasizing the adoption of healthy and sustainable eating behaviors. The remaining part will be dedicated to a group psychological intervention inspired by the principles of Well-Being Therapy and will be held by a trained psychologist. During these sessions, participants will be introduced to the six dimensions of psychological well-being and will be gradually provided with cognitive-behavioral strategies to enhance psychological well-being and seek a balance between the presented dimensions. Participants will be given cognitive-behavioral tools to recognize justification cognitive mechanisms and replace them with more functional cognitions. These objectives will also be achieved through the use of a food diary to highlight emotions and thoughts experienced during food intake.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Basic Nutritional Intervention
Description: Participants will receive treatment as usual (TAU) by participating in 6 weekly group sessions of two hours of a Basic Nutritional Intervention (BNI) held by a trained dietician. This course focuses on promoting healthier lifestyles through nutritional education, diet monitoring using a dedicated food diary, and recommendations for proper physical activity.
Study: NCT06461234

Intervention type: BEHAVIORAL
Intervention: Pelvic floor muscle training
Description: A therapist will instruct the patient to contract the anus, perineum as well as the urethra, until the patient masters the correct method.

Intervention type: OTHER
Intervention: Biofeedback electrical stimulation
Description: The therapist will place the electrodes of the instrument into the vagina, adjust the current value until the woman feels obvious contraction of the pelvic floor muscles but no pain, and instructs the patient to refer to the biofeedback mode for vaginal and anal contraction and relaxation.

Intervention type: OTHER
Intervention: Magnetic Stimulation
Description: The therapist will use the magnetic stimulator to intermittently stimulate the and adjust the stimulation intensity at any time according to the patient\&amp;amp;amp;#39;s condition, adjusting it until there is a clear sense of contraction and feel comfortable.

Intervention type: OTHER
Intervention: Magnetic stimulation combined with biofeedback electrical stimulation
Description: Pelvic floor magnetic stimulation for 30 minutes followed by biofeedback electrical stimulation.
Study: NCT06160674

Intervention type: OTHER
Intervention: COPD
Description: A vowel segmentation data set consisting of information from COPD and HC groups will be used to experiment with the classification performance of several Machine Learning techniques on different segments of a vowel recording.

Intervention type: OTHER
Intervention: COPD
Description: A vowel segmentation data set consisting of information from COPD and HC groups will be used to experiment with the classification performance of several Machine Learning techniques on different segments of a vowel recording.
Study: NCT05576597

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Butyrate
Description: 2 capsules butyrate supplement once a day for 12 weeks
Study: NCT06232707

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alnuctamab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pomalidomide
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Daratumumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Elotuzumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carfilzomib
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Specified dose on specified days
Study: NCT05359380

Intervention type: OTHER
Intervention: ADL performance
Description: ADL performance~All study groups address the following 10 ADL tasks in 9 different combinations of light temperature and light intensity in order possible differences to be revealed among the study groups and light combinations:~1. Phone Book Search (PBS), 2. Supermarket receipt (SupRe), 3. Book reading (BR), 4. Cellular message (CM), 5. Cellular entry search (CES), 6. Reading computer screen (RCS), 7. Drops bottle reading (DR), 8. Subtitles reading (SubRe), 9. Open door test (ODT), and, 10. Screwdriver test (ST).~The 9 light combinations are the following:~3000 K - 25 fc, 3000 K - 50 fc, 3000 K - 75 fc / 4000 K - 25 fc, 4000 K - 50 fc, 4000 K - 75 fc / 6000 K - 25 fc, 6000 K - 50 fc, 6000 K - 75 fc

Intervention type: OTHER
Intervention: ADL performance
Description: ADL performance~All study groups address the following 10 ADL tasks in 9 different combinations of light temperature and light intensity in order possible differences to be revealed among the study groups and light combinations:~1. Phone Book Search (PBS), 2. Supermarket receipt (SupRe), 3. Book reading (BR), 4. Cellular message (CM), 5. Cellular entry search (CES), 6. Reading computer screen (RCS), 7. Drops bottle reading (DR), 8. Subtitles reading (SubRe), 9. Open door test (ODT), and, 10. Screwdriver test (ST).~The 9 light combinations are the following:~3000 K - 25 fc, 3000 K - 50 fc, 3000 K - 75 fc / 4000 K - 25 fc, 4000 K - 50 fc, 4000 K - 75 fc / 6000 K - 25 fc, 6000 K - 50 fc, 6000 K - 75 fc

Intervention type: OTHER
Intervention: ADL performance
Description: ADL performance~All study groups address the following 10 ADL tasks in 9 different combinations of light temperature and light intensity in order possible differences to be revealed among the study groups and light combinations:~1. Phone Book Search (PBS), 2. Supermarket receipt (SupRe), 3. Book reading (BR), 4. Cellular message (CM), 5. Cellular entry search (CES), 6. Reading computer screen (RCS), 7. Drops bottle reading (DR), 8. Subtitles reading (SubRe), 9. Open door test (ODT), and, 10. Screwdriver test (ST).~The 9 light combinations are the following:~3000 K - 25 fc, 3000 K - 50 fc, 3000 K - 75 fc / 4000 K - 25 fc, 4000 K - 50 fc, 4000 K - 75 fc / 6000 K - 25 fc, 6000 K - 50 fc, 6000 K - 75 fc
Study: NCT05204888

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: myAirvo3
Description: For patients assigned to the HFNT intervention group, a myAirvo 3 device will be provided. The myAirvo 3 is for the treatment of spontaneously breathing patients, infant to adult, who would benefit from receiving high flow warmed and humidified respiratory gases. This includes patients who have had upper airways bypassed. The flow may be from 2 - 60 L/min depending on the patient interface. The myAirvo 3 is for patients in homes and long-term care facilities.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pulse oximeter
Description: A pulse oximeter will be provided to measure heart rate and pulse oximetry; subjects will enter and transmit the data on the smartphone once daily before 11AM. Heart rate and pulse oximetry measures will be taken after wearing the device for approximately 2 minutes.
Study: NCT06503523

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hypertonic Saline
Description: A bolus injection of hypertonic saline (7% NaCl) will be administered to the FDI muscle using a 1 mL syringe with a disposable needle (27G), and the volume of the bolus will be 0.1 mL

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Histamine
Description: A small drop of histamine dihydrochloride will be applied to a previously determined area on the volar forearm, followed by a prick through the drop

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cowhage
Description: This insertion is conducted by forceps using a stereomicroscope, and 30-35 spicules are gently rubbed into a 1 cm diameter skin area.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation (TMS)
Description: Transcranial magnetic stimulation (TMS) will be used to evoke motor-evoked potentials (MEPs) in the muscle of interest and cortical responses (TMSevoked potentials - TEPs) in the motor cortex with a figure-eight-shaped cone coil.
Study: NCT06262347

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME)
Description: The TOME intervention is a modified version of the personally-tailored opioid overdose prevention education and naloxone distribution (PTOEND) intervention (Winhusen et al. Evaluation of a personally-tailored opioid overdose prevention education and naloxone distribution intervention to promote harm reduction and treatment readiness in individuals actively using illicit opioids. Drug Alcohol Depend. Nov 1 2020;216:108265). Modifications include updating the knowledge assessment/education to reflect changes in the drug supply (i.e., the current high prevalence of fentanyl and increasing prevalence of xylazine) and the addition of items specific to pregnancy. Like PTOEND, TOME is a computer-guided intervention which utilizes REDCap to complete assessments and automatically generate personally-tailored feedback reports.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants randomized to the control condition will be offered three SAMHSA handouts.
Study: NCT04834297

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prapela SVS mattress
Description: The intervention will be using the Prapela SVS crib mattress to complement non-pharmacological management of NOWS for the purposes of prevention of pharmacological treatment of NOWS
Study: NCT05133843

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Assession of complete coronary physiology
Description: Assession of complete coronary physiology in TAVI candidates with intermediate coronary artery stenosis before and 6 months after TAVI.
Study: NCT06429033

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PEP (Purified Exosome Product)
Description: Injection of PEP into hypodermis of abdomen
Study: NCT06550180

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spinal anaesthesia group (S)
Description: Spinal anaesthesia is given to all patients in S group. They will receive 20 mg of 0.5% hyperbaric bupivacaine plus 25 microgram fentanyl

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Subcostal TAP block and spinal anesthesia group (STAP)
Description: patient receive Subcostal TAP block before spinal anesthesia. Patients in STAP group will receive 20 ml of 0.25% isobaric bupivacaine for each side before spinal anesthesia
Study: NCT04475731

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ponatinib
Description: Ponatinib 45 mg/day x 4 weeks x 3 courses.~+/- chemotherapy:~* vincristine or~* L-VAMP (leucovorin, vincristine, aracytin, methotrexate, prednisone)
Study: NCT05968300

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: INFORMED-Living Well
Description: 1) LHW outreach support providing responsive education and support; and 2) a 6-week automated SMS text messaging

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Text Messaging Only
Description: A 6-week automated SMS text messaging
Study: NCT06311565

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Individuals in this group will be trained on acquiring healthy lifestyle behaviors to protect against colorectal cancer. Training will be individual, face-to-face and in the form of question and answer. At the end of the training, training brochures prepared by the researchers after taking expert opinions will be distributed to the participants. The training will take approximately 25-30 minutes. The training will take place in the training hall at the family health center.
Study: NCT06513078

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Static cupping
Description: 4 cups were placed on the gastrocnemius, negative pressure was applied and participants lay prone on a table for 10 minutes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Static sham cupping
Description: 4 cups were placed on the gastrocnemius, negative pressure was applied and participants lay prone on a table for 10 minutes. A pin hole in the cup allowed pressure to slowly leak out during the treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dynamic cupping
Description: 4 cups were placed on the gastrocnemius, negative pressure was applied and participants lay prone on a table for 5 minutes, then did ankle exercises for 3 minutes, and lastly lay prone on the table for the last 3 minutes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Dynamic sham cupping
Description: 4 cups were placed on the gastrocnemius, negative pressure was applied and participants lay prone on a table for 5 minutes, then did ankle exercises for 3 minutes, and lastly lay prone on the table for the last 3 minutes. A pin hole in the cup allowed pressure to slowly leak out during the treatment.
Study: NCT05806385

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryoablation
Description: Tumor ablation before neoadjuvant chemotherapy

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Cryoablation combined with PD1 Inhibitor
Description: Combination of cryoablation with PD1 inhibitor before neoadjuvant chemotherapy
Study: NCT05788172

Intervention type: OTHER
Intervention: Iron isotope dilution
Description: Menstrual blood loss will be determined using the iron isotope dilution technique and compared to the amount determined via the alkaline hematin method.

Intervention type: OTHER
Intervention: Alkaline hematin method
Description: Menstrual blood loss will be determined using the alkaline hematin method and compared to the amount determined via the iron isotope dilution technique.
Study: NCT05946993

Intervention type: OTHER
Group type: OTHER
Intervention: Physiotherapy
Description: participant will have 2 x 1h exercise classes per week with a physiotherapist, who will develop individualized plans based on medical history and scan reviews. Participants will be progressively guided through the programme, incrementally increasing in intensity or with modifications based on symptomatic presentation. This will be based on their baseline strength and cardiovascular fitness testing and grounded on evidence-based protocols previously demonstrating an effect in this patient population. Individualised tailored exercise programme which includes strength and conditioning.
Study: NCT05984394

Intervention type: DIAGNOSTIC_TEST
Intervention: BAL antigen-specific Th1 cells and Th17 cells, ILC and MAIT
Description: BAL antigen-specific Th1 cells and Th17 cells, ILC and MAIT
Study: NCT06652555

Intervention type: OTHER
Intervention: Group 1
Description: without Intervention
Study: NCT04413604

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Young children's milk (1-<3)
Description: young children's milk containing protein, energy and fat and micronutrients, in accordance with global and local nutritional recommendations for ages 1-3.
Study: NCT06457204

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pramipexole (from manufacturing site 1)
Description: Pramipexole (from manufacturing site 1) - test treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pramipexole (from manufacturing site 1)
Description: Pramipexole (from manufacturing site 1) - test treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pramipexole (from manufacturing site 2)
Description: Pramipexole (from manufacturing site 2) - reference treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pramipexole (from manufacturing site 2)
Description: Pramipexole (from manufacturing site 2) - reference treatment
Study: NCT04889794

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GPS clinical intervention
Description: Nurses and doctors in exposed FMGs and home care teams (HCTs) will be asked to refer to the FMG pharmacist all seniors undergoing cognitive evaluation OR referred to a memory clinic OR recently diagnosed with a cognitive disorder, for a complete and critical review of their medication therapy. FMG pharmacists will be asked to conduct an interview with each referred senior and his or her caregiver, if applicable, in order to establish the best possible treatment regimen. They will compare the information collected with another reliable data source (e.g., pharmacy records) in order to perform medication reconciliation and will then evaluate the medication related problems. Pharmacist will establish a care plan and the follow-ups to be carried out with the patient in collaboration with the health care team. There will be no drug or devices tested, it is a human clinical intervention by a pharmacist.
Study: NCT04533165

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 12 week exercise prescription targeting 3 days of at least 30 min of aerobic exercise and 2 days of resistance exercise per week. Adapted to individual abilities, goals, and needs. Exercise intensity targets a 6-7 out of 10 on a 0-10 rate of perceived exertion scale.
Study: NCT06594094

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: HG302
Description: Once intravenous injection; The duration of the study is about 32 weeks for each subject, including a 6 weeks screening period, enrollment visit, treatment visit, and 26 weeks follow-up period.
Study: NCT06610279

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-951
Description: TAK-951 SC injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: TAK-951 matching placebo SC injection
Study: NCT06560541

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: UKMRC9
Description: UKMRC9 is a low glycemic index and polyphenol-rich red pigmented rice

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: UKMRC9
Description: UKMRC9 is a low glycemic index and polyphenol-rich red pigmented rice

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: White rice
Description: White rice refers to a local polished rice

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: White rice
Description: White rice refers to a local polished rice
Study: NCT05003921

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AlloRx
Description: cultured allogeneic adult umbilical cord derived mesenchymal stem cells