TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06761950

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Level laser therapy
Description: The patient received low-level laser therapy three times per week for four weeks, with immobilization maintained. The Mustang 2000 Laser device was used with an infrared laser probe to accelerate tendon healing. The device's specifications include peak power output of 15W, power density of 15W/cm2, wave length of 890nm, pulse frequency of 100Hz, spherical size of 0.002cm2, pulse duration of 130 ns, exposure duration of 60 sec, and energy density of 5.85J/cm2.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Placebo low level laser therapy
Description: Same as in the study group except turning on the device with covering probe by aluminum foil and ask patient to wear sun glasses to obtain the placebo effect 3 sessions per week for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: medical treatment
Description: the patients received their drugs from their treating physicians

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: medical treatment
Description: the patients received their drugs from their treating physicians

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical therapy program
Description: patients received the traditional program after flexor tendon repair involving isometric exercise, stretching and mobilizations

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: physical therapy program
Description: patients received the traditional program after flexor tendon repair involving isometric exercise, stretching and mobilizations
Study: NCT06204718

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard pelvic floor exercises
Description: Pelvic floor muscle exercises will be given as 2 separate exercises including fast and slow contractions. For fast contractions, participants will be asked to contract their pelvic floor muscles strongly, hold them contracted for 5 seconds, and then relax them. For slow contractions, participants will be asked to gradually contract the pelvic floor muscles, hold them at maximum contraction for 5 seconds, and relax them gradually. Participants will be asked to perform 10 slow contractions after every 10 fast contractions. The aim is to train strength, coordination, endurance, and symmetry of pelvic floor muscles, motor learning and control, dynamic lumbopelvic stability, pelvic floor, and abdominal co-contraction. Every day, 10 fast, and 10 slow contractions with a total of 20 repetitions will be applied without changing the number by modifying the exercises every week. It will be applied for a total of 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Involuntary reflexive pelvic floor exercises
Description: Reflexive exercises (jump, squat jump, etc.) with 20 repetitions per day will be applied to the participants for 12 weeks with modifications every week.
Study: NCT06471816

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dialogue Based Early Detection
Description: Before the biannual parent-teacher meeting, both the kindergarten teacher and the parents will complete the Early Worry Questionnaire containing 39 items related to development and well-being of the individual child. For each item the respondents are asked to indicate if they during the last three months have been concerned. In the parent-teacher meeting they will discuss their possible concerns and try to reach an agreement on how to evaluate the child. If necessary, possible supportive interventions or further assessments locally in the kindergarten or in the public services will be decided.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional parent-teacher meeting
Description: This is an annual or biannual meeting that is prepared by the kindergarten teacher where (s)he reports on the child's appearance / behaviour and possible challenges as to development and behaviour from an educationalist's view. There are no common templates for the agenda of such meetings, however, usually the kindergarten teacher's perspective and opinion will dominate.
Study: NCT06320028

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-Invasive Transcranial Focused Ultrasound
Description: The ultrasound will be delivered for 10 minutes per treatment session targeting to the participant's amPFC.
Study: NCT04520737

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical Prehabilitation
Description: The prehabilitation program consists of the following interventions: in-hospital high-moderate intensive exercise training, nutritional assessment and high-protein supplementation, smoking cessation, psychological support and Comprehensive Geriatric Assessment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical Prehabilitation
Description: The prehabilitation program consists of the following interventions: in-hospital high-moderate intensive exercise training, nutritional assessment and high-protein supplementation, smoking cessation, psychological support and Comprehensive Geriatric Assessment.
Study: NCT05020990

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens A (delefilcon A)
Description: Daily disposable for one week

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens A (delefilcon A)
Description: Daily disposable for one week

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens B (stenfilcon A)
Description: Daily disposable for one week

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens B (stenfilcon A)
Description: Daily disposable for one week
Study: NCT04675203

Intervention type: PROCEDURE
Intervention: Tooth extraction
Description: Tooth extraction
Study: NCT06513377

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Performance test
Description: The participant will be asked to execute a protocol in the movement lab that induces progressive feelings of fatigue. This protocol includes a sequence of relevant functional activities, such as stair walking, slope walking, crouching, walking different path shapes. During this execution the Ratings of Perceived Exertion will be questioned, and simultaneously physiological and movement data will be collected.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Performance test
Description: The participant will be asked to execute a protocol in the movement lab that induces progressive feelings of fatigue. This protocol includes a sequence of relevant functional activities, such as stair walking, slope walking, crouching, walking different path shapes. During this execution the Ratings of Perceived Exertion will be questioned, and simultaneously physiological and movement data will be collected.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Performance test
Description: The participant will be asked to execute a protocol in the movement lab that induces progressive feelings of fatigue. This protocol includes a sequence of relevant functional activities, such as stair walking, slope walking, crouching, walking different path shapes. During this execution the Ratings of Perceived Exertion will be questioned, and simultaneously physiological and movement data will be collected.
Study: NCT04752137

Intervention type: DRUG
Group type: OTHER
Intervention: Indocyanine green
Description: The SPY PHI and its dye Indocyanine Green dye (ICG) is a non-invasive device that is connected to a light source tower that is already available in the hospital in the operating room under Gynecology and Obstetrics Equipment. This is a special light source lamp that allows to test for vascularity in the soft tissues intraoperatively. Previous research in animal models proved the concept that the increased vascularity in tumors can be used to use this device to improve intraoperative assessment of tumor margins during resection. Our study will help to establish a correlation between activity with the dye and histological findings. This information has the potential to help sarcoma patients by avoiding staged surgeries, decreasing hospitalization times, and decreasing the likelihood of local recurrence by improving margin quality.

Intervention type: DEVICE
Group type: OTHER
Intervention: SPY-PHI
Description: The SPY PHI and its dye Indocyanine Green dye (ICG) is a non-invasive device that is connected to a light source tower that is already available in the hospital in the operating room under Gynecology and Obstetrics Equipment. This is a special light source lamp that allows to test for vascularity in the soft tissues intraoperatively. Previous research in animal models proved the concept that the increased vascularity in tumors can be used to use this device to improve intraoperative assessment of tumor margins during resection. Our study will help to establish a correlation between activity with the dye and histological findings. This information has the potential to help sarcoma patients by avoiding staged surgeries, decreasing hospitalization times, and decreasing the likelihood of local recurrence by improving margin quality.
Study: NCT04746482

Intervention type: PROCEDURE
Intervention: single visit root canal retreatment
Description: cases that were subject to root canal retreatment performed in single visit
Study: NCT02686151

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Letrozole
Description: used after oocyte retrieval

Intervention type: DRUG
Group type: OTHER
Intervention: Polygeline
Description: used after oocyte retrieval

Intervention type: DRUG
Group type: OTHER
Intervention: Sodium Chloride
Description: used after oocyte retrieval

Intervention type: DRUG
Group type: OTHER
Intervention: dexamethasone
Description: used after oocyte retrieval
Study: NCT05948228

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: giomer based bioactive gel
Description: Application of bioactive gel to prevent white spot lesions in orthodontic patients

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluoride gel
Description: Application of fluoride gel to prevent white spot lesions in orthodontic patients
Study: NCT05363293

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL 001
Description: a crystal engineered lithium-salicylate-proline lithium delivery product

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL 001
Description: a crystal engineered lithium-salicylate-proline lithium delivery product

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL 001
Description: a crystal engineered lithium-salicylate-proline lithium delivery product

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL 001
Description: a crystal engineered lithium-salicylate-proline lithium delivery product

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL 001
Description: a crystal engineered lithium-salicylate-proline lithium delivery product

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: matching placebo formulation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: matching placebo formulation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: matching placebo formulation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: matching placebo formulation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: matching placebo formulation
Study: NCT04872933

Intervention type: OTHER
Group type: OTHER
Intervention: Kidney Beam Online Platform
Description: Kidney Beam is a wellbeing digital health intervention platform that offers patients living with kidney disease a way to improve their physical activity and boost their mental health through live and on demand movement classes and expert educational videos, while remaining in their own home. Kidney Beam is led by specialist kidney professionals, including renal physiotherapists and renal counsellors, from a number of different NHS Trusts and backgrounds, as well as people living with kidney disease.

Intervention type: OTHER
Group type: OTHER
Intervention: Kidney Beam Online Platform
Description: Kidney Beam is a wellbeing digital health intervention platform that offers patients living with kidney disease a way to improve their physical activity and boost their mental health through live and on demand movement classes and expert educational videos, while remaining in their own home. Kidney Beam is led by specialist kidney professionals, including renal physiotherapists and renal counsellors, from a number of different NHS Trusts and backgrounds, as well as people living with kidney disease.
Study: NCT05391425

Intervention type: OTHER
Intervention: no intervention
Description: no intervention planned, since it is an observational study

Intervention type: OTHER
Intervention: no intervention
Description: no intervention planned, since it is an observational study
Study: NCT05405491

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PCR based strategy
Description: Early adjustment of antimicrobial therapy according to the results of a multiplex PCR-based testing, used in addition to standard microbiological culture of the tracheal aspirate, in immunocompromised patients with suspected VAP or HAP requiring MV

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard care
Description: Broad-spectrum antimicrobial therapy adjustment after results of standard microbiological culture of the tracheal aspirate in immunocompromised patients with suspected VAP or HAP requiring MV
Study: NCT06463704

Intervention type: OTHER
Intervention: There is no intervention
Description: There is no intervention
Study: NCT04419740

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness based psychological intervention
Description: Women in the intervention group will have to use an application during 1 month. They will do meditation during 15 minutes each day.
Study: NCT05135195

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In-House Developed VR Platform - AMD, DR, Glaucoma
Description: Participants will conduct experiments using commercial VR headsets and controllers. Visual impairments will be systematically simulated in VR. There are three visual impairment simulations (AMD, DR, and glaucoma) at three levels of severity (mild, moderate, or severe). Symptoms' simulation tools include a gaussian blur shader, distortion shader, and a culling mask with a gray spot in the middle.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In-House Developed VR Platform - Glaucoma
Description: In the second set of experiments, a multidimensional visual impairment simulation of a single pathology (glaucoma) will be used at three levels of severity (mild, moderate, or severe). The post-processing package to simulate includes glare, difficulty in light, change adaptation, ambient occlusion, visual clutter, and overall blurred effect. The shader graph package will be used to create a distortion localized on assets surfaces only.
Study: NCT03886337

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Germicidal lighting
Description: Germicidal ambient lighting
Study: NCT06274203

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin D3
Description: Subjects within SCD as well as healthy controls, received monthly oral vitamin D3 dose, for 6 months, according to the baseline status of vitamin D as follows: sufficient (\>30 ng/mL): 100,000 IU, insufficient (20-29.9 ng/mL): 150,000 IU, and deficient (\<20 ng/mL): 200,000 IU.
Study: NCT05721963

Intervention type: DIAGNOSTIC_TEST
Intervention: No interventions.
Description: No interventions.
Study: NCT05487781

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tirfostina/L-Carnitina
Description: Estudio clínico fase 1 para describir la seguridad biológica y la farmacocinética de la tirfostina AG-17

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tirfostina/L-Carnitina
Description: Estudio clínico fase 1 para describir la seguridad biológica y la farmacocinética de la tirfostina AG-17

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tirfostina/L-Carnitina
Description: Estudio clínico fase 1 para describir la seguridad biológica y la farmacocinética de la tirfostina AG-17
Study: NCT05489055

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iopamidol
Description: A contrast bolus of iopamidol-370 (370 mg I/ml) (iopamidol injection; Consun Pharmaceutical, China) was injected at a ﬂow rate of 4.5-6 mL/s through an 18-20-gauge intravenous antecubital catheter by using a power injector (Ulrich, Germany). The total dose of iopamidol-370 was approximately 0.9 ml /kg body weight.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Iopamidol
Description: A contrast bolus of iopamidol-370 (370 mg I/ml) (iopamidol injection; Consun Pharmaceutical, China) was injected at a ﬂow rate of 4.5-6 mL/s through an 18-20-gauge intravenous antecubital catheter by using a power injector (Ulrich, Germany). The total dose of iopamidol-370 was approximately 0.9 ml /kg body weight.
Study: NCT06475950

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kid'EM app experimental group
Description: In the Kid'EM app experimental group arm, only the application used differs. Visits are organized in the same way as in the controle app arm.~Visit 0 (Inclusion) + Visit 1 (V1) : Physical visit~Children are included in the study by the investigator, formalized by signing a consent form.~Parents fill in questionnaires~Visit 2 (when 1st objective is set):~Telephone interview to assess performance and satisfaction levels after the first goal has been set.~Visit 3 (when setting the 2nd goal):~Telephone interview to assess performance and satisfaction levels after the second goal has been set.~Visit 4 (week 14 - end of study): Physical visit~The questionnaires are again completed by the parents, either directly on a tablet or on paper for later input.~Visit 4 bis:~Telephone interview to assess performance and satisfaction levels after the work on the first two objectives.~Visit 5 (focus group, optional post-study visit)

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Kid'EM app control group
Description: Use of control application without guidance for goal setting~Visit 0 (Inclusion) + Visit 1 (V1) : Physical visit~Children are included in the study by the investigator, formalized by signing a consent form.~Parents fill in questionnaires~Visit 2 (when 1st objective is set):~Telephone interview to assess performance and satisfaction levels after the first goal has been set.~Visit 3 (when setting the 2nd goal):~Telephone interview to assess performance and satisfaction levels after the second goal has been set.~Visit 4 (week 14 - end of study): Physical visit~The questionnaires are again completed by the parents, either directly on a tablet or on paper for later input.~Visit 4 bis:~Telephone interview to assess performance and satisfaction levels after the work on the first two objectives.~Visit 5 (focus group, optional post-study visit)
Study: NCT06265740

Intervention type: OTHER
Group type: OTHER
Intervention: vaginal swab
Description: Any pregnant woman attending the obstetrics department of Clermont-Ferrand University Hospital who requires a vaginal swab (VS) for her clinical situation (routine care) will be offered the study. If she accepts, the usual swab will be doubled and performed simultaneously in a single procedure using two swabs. The first swab will be sent to the laboratory and used for diagnosis. The second swab will be used for microbiota analysis.
Study: NCT01929850

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparscopic Sleeve Gastrectomy
Description: The laparoscopic sleeve gastrectomy involves the placement of 5 trocars. A leak check may be performed at the same time by insufflating with a gastroscope with the remnant gastric section submerged in irrigation fluid and by infusing sterile methylene blue through a nasogastric tube. The staple line may be oversewn (3-0 Vicryl, Ethicon), only along the bleeding and leakage areas, or areas with the potential for such complications. A nasogastric decompression tube placed to monitor bleeding and an intraperitoneal drain was placed under an anastomotic stoma.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Weight Watchers Program
Description: Intensive medically supervised nutritional and exercise therapy

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Weight Watchers Program
Description: Intensive medically supervised nutritional and exercise therapy
Study: NCT04685915

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibrutinib
Description: Capsule, taken by mouth once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Copanlisib
Description: Intravenous Infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Capsule, taken by mouth twice daily
Study: NCT04610944

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Changing Talk Online (CHATO)
Description: Three, one-hour training modules highlighting barriers and ineffective communication behaviors with older adults while teaching and modeling alternative, effective communication.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Changing Talk Online (CHATO)
Description: Three, one-hour training modules highlighting barriers and ineffective communication behaviors with older adults while teaching and modeling alternative, effective communication.
Study: NCT04608851

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E. coli Nissle
Description: 1 ml of oral suspension containing 10 E8 CFU /ml of E. coli Nissle strain

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo control
Description: 1 ml oral syrup consisting of Saccharum 630 mg/g and Aqua purificata 370 mg/g.
Study: NCT04768231

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifampin
Description: The target dose of 35mg/kg will be reached supplementing fixed-dose combination tablets (standard dose) with rifampin-only tablets.
Study: NCT05780567

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3616 capsules, Letrozole, Anastrozole, Tamoxifen
Description: TQB3616 is a novel Cyclin-dependent kinase (CDK) 4/6 inhibitor and currently being used in the treatment of a variety of malignant solid tumors.~Letrozole combined with Anastrozole and Tamoxifen is an endocrine therapy that involves adding, blocking, or removing hormones. It can be used for conditions that affect hormone levels, such as breast cancer.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsules, Letrozole, Anastrozole, Tamoxifen
Description: Letrozole combined with Anastrozole and Tamoxifen is an endocrine therapy that involves adding, blocking, or removing hormones. It can be used for conditions that affect hormone levels, such as breast cancer.
Study: NCT06230081

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacain 5 mg/ml + Clonidine
Description: Drug used in the block