TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06124417

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sertraline
Description: The initial dose ranged from 25 to 50 mg, taken orally once daily, and the dosage was adjusted based on the patient's response to the medication.
Study: NCT04128189

Intervention type: BIOLOGICAL
Group type: SHAM_COMPARATOR
Intervention: Shingrix
Description: Both arms receive standard 2 doses of Shingrix. Transplanted subjects may receive 3rd dose.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Shingrix
Description: Both arms receive standard 2 doses of Shingrix. Transplanted subjects may receive 3rd dose.
Study: NCT05291273

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Closed Kinetic Chain Upper Extremity Stability Test
Description: Each patient receive the same intervention, the Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST). The CKCUEST is a functional test which assess shoulder's stability. Patient is in push-up position, with 91 cm between his hands. His body is straight and his foots are squeeze. patient has to touch his hand with his other one and returns in the initial position. Then, patient repeats this movement with his other hand, etc, during 15 secondes. The CKCUEST score is the movement's number performed.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Prone Bridge Test
Description: The prone bridge test also known as the plank or hover measures the muscular endurance of the abdominal muscles. Subjects will start in the down push up position with their feet together and their hands shoulder width apart. When the test starts the subject will push up to the prone bridge position so they are resting on their hands and toes making sure they maintain a straight line from the shoulders through the hips to the knees. The outcome measure will be the time where the subject stay in this position.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Measurement of the muscle strength of the shoulder complex
Description: Maximum isometric force of the external and internal rotators and abductors/adductors measured by a dynamometer.
Study: NCT05051514

Intervention type: DIAGNOSTIC_TEST
Intervention: Evaluation
Description: To examine the differences in postural stability, anxiety/depression, and quality of life of the patients according to the severity of Obstructive Sleep Apnea Syndrome.
Study: NCT06086834

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: McKenzie Retraction Exercises
Description: McKenzie Retraction exercises 5 days a week and 10-15 times for active exercises and 5-6 repetitions of clinician assisted exercise for a period of 4 weeks and a rest interval of 2 minutes between exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bruegger's Exercise
Description: Bruegger's Exercise will be started from 10 seconds hold to 30 seconds with 2 seconds increment in every session. Rest time will be 30 seconds, 4 sets 12 times repetition, for duration of 30 mins per session, 5 days a week for a period of 4 weeks.
Study: NCT06259539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: YouTube nutrition education
Description: For those in the intervention group, the YouTube training modules had step-by-step recipe demonstrations, strategies on how to get your child to eat more new foods, social stories, First-Then visual chart, and other nutrition education materials. All the videos were less than 5 minutes long, and parents were assigned 2 videos per week for 8 consecutive weeks. Parents answered 2 open-ended questions each week related to the educational materials they reviewed.
Study: NCT06628804

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Artemisia and green tea extracts
Description: Artemisia and green tea extracts 700 mg/day for 8 weeks
Study: NCT05551611

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Playgroup
Description: The mobile game will be sent to the students via a link and the students are allowed to install it on their mobile phones with android and ios operating systems. The internet required for the download was provided by the researcher. For the students who did not have a smart phone in the playgroup, the game would be started from the researcher's phone and the game was played sequentially. All students were allowed to use headphones while playing the game. In order to log in to the game, an account was created on behalf of each student, and the game user name and password were sent to the students by e-mail. It was ensured that they did not communicate with anyone and did not receive help during the game with the supervision of the researcher. Waited until each participant completed the game. Then, the mobile game was deleted from the smartphones of all participants, and the download link was inactive until the research process was completed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: The researcher gave a theoretical lesson through the presentation prepared in the powerpoint program about the birth management of a breech-presented fetus in the classroom as in the traditional education method.
Study: NCT06514833

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: lifestyle recommendations to nap regularly
Description: Participants will receive lifestyle recommendations to nap regularly for 15-30 minutes between 12:00 and 15:00

Intervention type: OTHER
Group type: OTHER
Intervention: No recommendations to nap regularly
Description: No lifestyle recommendations to nap regularly
Study: NCT06628804

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 700 mg/day for 8 weeks
Study: NCT05397678

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BCG-Denmark
Description: AJ vaccines, Copenhagen 1331 strain

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: BCG-Bulgaria
Description: BB-NCIPD Ltd., BCG-SL 222 Sofia strain
Study: NCT05721287

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SBS-1000
Description: SBS-1000 administered as a single continuous IV infusion over 60 minutes

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Normal saline (0.9% sodium chloride \[NaCl\]) administered as a single dose IV infusion over 60 minutes
Study: NCT05237492

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tramadol
Description: Blood samples will be drawn from 15 patients. Tramadol will be added to all this samples in-vitro and its influence on platelets´ function will be measured.
Study: NCT05662527

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: One dosage of 4mg/kg (maximum of 400mg)
Study: NCT04985851

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: durvalumab + anlotinib
Description: Approximately 64 patients who complete the 4 cycles of durvalumab + EP treatment and don't have progressive diseases (Non-PD patients) will be randomized in a 1:1 ratio to receive maintenance treatment durvalumab + anlotinib (Arm 1) or durvalumab (Arm 2) until confirmed progressive disease.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Durvalumab
Description: durvalumab
Study: NCT05236504

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Melatonin and magnesium-containing pod
Description: A 50-100mL hot water drink, obtained from a coffee pod machine, containing 1.9mg of melatonin and 200mg of magnesium in a powdered form, will be ingested 30 minutes before bedtime. Total duration of this intervention: 4 weeks, after which 1 week of washout will occur, before switching to the other intervention.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo comparator
Description: A 50-100mL hot water drink of identical taste, obtained from an identical pod with the same ingredients except melatonin and magnesium, will be ingested 30 minutes before bedtime. Total duration of this intervention: 4 weeks, after which 1 week of washout will occur, before switching to the other intervention.
Study: NCT06468670

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sintilimab，programmed death 1 monoclonal antibody
Description: short-course radiotherapy~+sintilimab (200mg, iv, D1, Q3W)
Study: NCT06132958

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sacituzumab tirumotecan
Description: 4 mg/kg of sacituzumab tirumotecan by IV infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin
Description: 60 mg/m\^2 of doxorubicin by IV Infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: 80 mg/m\^2 of paclitaxel by IV infusion
Study: NCT06337656

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Galileo WBV
Description: Side-Alternating Whole-Body Vibration Training
Study: NCT06215846

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BioTTT001 injection
Description: BioTTT001 is administered as a single Intratumoral injection. The dose groups to be infusion were 5×10\^9 VP, 5×10\^10 VP and 5×10\^11 VP based on the 3+3 dose escalation principle.
Study: NCT05630014

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aliviado DSD Caregiving Mastery Program
Description: Family caregiver intervention consisting of mHealth-app based educational videos and articles; caregiver-administered assessment tools and care plans; and motivational push notification reminders and encouragements.
Study: NCT06163144

Intervention type: OTHER
Intervention: lab investigation
Description: Platlets count by : advia cell counter principles . This flow cytometry-based system uses light scatter, differential white blood cell (WBC) lysis, and myeloperoxidase and oxazine 750 staining to provide a complete blood cell count, a WBC differential, and a reticulocyte count. A cyanide-free method is used to measure hemoglobin colorimetrically.~\*Automated cell counters~* Advia 2120 8 difference~* PLT , parameters , MPV . Prothrombin time , prothrombin concentration , International normalized ratio , activated partial thromboplastin time . BUN, Serum Createnin Serum Albumin Serum Ca, Ph, PTH HBsAg, HCV - Abs Erythrocyte sedimintation rate ,C- reactive protein . 2.Specific lab: C3 - C4, Anti Neuclear Antibody, Anti douple stranded DNA , if suspect lupus . PCR for HCV or HBV serum lactate if sepsis is suspected. drugs level if Addiction is suspected.

Intervention type: OTHER
Intervention: lab investigation
Description: Platlets count by : advia cell counter principles . This flow cytometry-based system uses light scatter, differential white blood cell (WBC) lysis, and myeloperoxidase and oxazine 750 staining to provide a complete blood cell count, a WBC differential, and a reticulocyte count. A cyanide-free method is used to measure hemoglobin colorimetrically.~\*Automated cell counters~* Advia 2120 8 difference~* PLT , parameters , MPV . Prothrombin time , prothrombin concentration , International normalized ratio , activated partial thromboplastin time . BUN, Serum Createnin Serum Albumin Serum Ca, Ph, PTH HBsAg, HCV - Abs Erythrocyte sedimintation rate ,C- reactive protein . 2.Specific lab: C3 - C4, Anti Neuclear Antibody, Anti douple stranded DNA , if suspect lupus . PCR for HCV or HBV serum lactate if sepsis is suspected. drugs level if Addiction is suspected.
Study: NCT05855382

Intervention type: OTHER
Intervention: Persistent COVID-19
Description: To determine the prevalence of persistent COVID-19 diagnosis in the current study, we will identify adults between 18 and 100 years of age who have had at least one positive SARS-CoV-2 RT-qPCR test from the COVID-19 database maintained by the SEREMI of Health in Punta Arenas between July 2022 and July 2023.
Study: NCT05596864

Intervention type: DIAGNOSTIC_TEST
Intervention: gastric contrast ultrasound
Description: Gastric contrast ultrasound (GCUS) refers to that the patient fills the stomach cavity with oral water, contrast agent and ultrasound contrast agent before the examination to remove the gas in the stomach cavity and fill the stomach cavity to become a homogeneous echo area and form a good acoustic sound. Interface contrast, more clearly showing the gastric wall hierarchy and the ultrasound examination method of the lesions.~In this way, not only the changes of the gastrointestinal mucosa can be found, but also the submucosal tumors of the gastrointestinal tract can be clearly displayed, the internal structural characteristics of the tumor, the extent of the lesions, the depth of infiltration, the TNM staging of the tumor, and the lesions of the surrounding organs can be displayed.
Study: NCT04802226

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: self exclusion procedure
Description: self exclusion procedure( responsible gambling tool)

Intervention type: OTHER
Group type: OTHER
Intervention: self exclusion procedure
Description: self exclusion procedure( responsible gambling tool)
Study: NCT02119728

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HPPH
Description: Undergo photodynamic therapy with HPPH

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Light Infusion Therapy™
Description: Undergo photodynamic therapy with HPPH

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: therapeutic conventional surgery
Description: Undergo standard of care surgery
Study: NCT05986409

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: light cover
Description: 10 wards were randomly selected as the intervention group (opaque black tape covering part of the light source), and another 10 wards were selected as the control group (no intervention).
Study: NCT05657379

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Other: Product X moisturizer
Description: Product X moisturizer containing Hyaluronic Acid and Rosa Damascena Flower Water
Study: NCT05604859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: Methylprednisolone:1-2mg/kg/d(or other glucocorticoid equivalent to methylprednisolone 1-2mg/kg/d),ivgtt,3-5 days.If disease progression occurs after completion of treatment, the dose of salvage therapy (methylprednisolone \> 2mg/kg/d or other glucocorticoid equivalent to methylprednisolone \> 2mg/kg/d) was continued for another 3-5 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intravenous immunoglobulin
Description: intravenous immunoglobulin:0.2g-0.4g/kg/d,ivgtt, 3-5 days.If disease progression occurs after completion of treatment, the dose of salvage therapy (IVIG 0.4g/kg/d) was continued for another 3-5 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tocilizumab
Description: Tocilizumab:4mg/kg, once
Study: NCT05914207

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle modifications
Description: Written suggestions on lifestyle modifications including duration of sleep, meal frequency, reduce screen time, exercise duration, food to avoid.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vestibular rehabilitation exercise
Description: Each participant will be taught simple home-based vestibular rehabilitation exercise, which needs to be repeated
Study: NCT04080778

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: magnetic seizure therapy (MST)
Description: MST will be performed with the MagPro XP (120 V) device under anesthesia 2-3 times a week up to 15 sessions.Treatment is performed by magnetic stimulation of both hemispheres inducing a focal stimulation above vertex, using a serial of pulse trains with a frequency of at least 25 Hz but up to 100 Hz for 4-6 s (up to 10 s), which is sufficient to induce a tonic clonic seizure.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: electroconvulsive therapy (ECT)
Description: ECT will be performed with MECTA 5000Q, 4th generation ECT devices provided by MECTA Corporation under anesthesia 2-3 times a week up to 15 sessions. For initial procedure Seizure Threshold (ST) will be estimated by empiric titration in the first session of each participant. ST will be then determined as by the manufacturer of ECT Device by the titration schedule for the initial titration session. The subsequent treatment sessions were dosed at 6 times the charge of the seizure threshold.
Study: NCT05748808

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Use of biofeedback and virtual reality in the treatment of aggressive outbursts
Description: Participants are trained to identify their physiological response when they are relaxed and when an outburst is coming. They are treated with cognitive, behavioral and emotional self-regulation therapies for managing anger and learning positive coping skills. Biofeedback toghether with virtual reality help them to improve their recognition and control of emotions.
Study: NCT05604859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low molecular weight heparin
Description: Low molecular weight heparin:100U/kg, qd or q 12h,IH,4-7 days

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional treatment
Description: conventional treatment，including symptomatic and supportive treatment, antiviral treatment etc.
Study: NCT06414577

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan Liposomal combined With Nituzumab
Description: Irinotecan liposomal: 70mg/m2, ivgtt, d1; Nituzumab: 400 mg, igvtt, d1 One treatment cycle every two weeks for up to 8 cycles, or until disease progression, intolerable toxicity, death, and investigator judgment of no further benefit
Study: NCT06397235

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DEB-TACE+HAIC
Description: CalliSpheres (100-300 µm) loaded with pirarubicin for transarterial chemombolization: Typically, one vial of the beads was loaded with 60 mg pirarubicin. If blushed tumors is still visible after the embolization with one vial of beads, regular microspheres (8spheres) with diameters of 100-700 μm are additionally injected.~RALOX-based regimen for hepatic arterial infusion chemotherapy: oxaliplatin, 85 mg/m2 infusion for 2 hours; Raltitrexed, 3 mg/m2 infusion for 0.5 hour.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DEB-TACE
Description: CalliSpheres (100-300 µm) loaded with pirarubicin for transarterial chemombolization: Typically, one vial of the beads was loaded with 60 mg pirarubicin. If blushed tumors is still visible after the embolization with one vial of beads, regular microspheres (8spheres) with diameters of 100-700 μm are additionally injected.
Study: NCT03625999

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: video game training exercise
Description: The game, called The Silent Service and developed by our collaborators, is an online game with an underwater theme, and is comprised of 5 distinct mini-games, each of which demands auditory attention. The mission is to navigate an underwater scene, listening and responding to 'sonar' (e.g., an oddball in a stream of sounds). For example, participants may have to respond to an oddball sound stream to protect their submarine from a looming sea monster, while successfully ignoring a distractor sound stream (responses to the distractor sound stream allow the sea monster to damage the submarine). The five games share the same underlying framework of detecting oddballs while ignoring distractors but have unique artwork and 'backstories' to keep players interested. There is a hierarchical reward structure for 'leveling up' across the game that helps players to stay engaged and interested while playing.
Study: NCT04901273

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Homologous PRP injections
Description: Patients will be treated with a single injection of Homologous PRP (5 ml) in the knee joint affected by osteoarthritis.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo injection (saline solution)
Description: Patients will be treated with a single injections of saline solution (5 ml) in the knee joint affected by osteoarthritis
Study: NCT05604859

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional treatment
Description: conventional treatment，including symptomatic and supportive treatment, antiviral treatment etc.
Study: NCT05007366

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Real-time gait biofeedback
Description: The RTGBF interventions will include eighteen step gait training sessions. The intervention will gradually increase to 3,000 steps at the 9th and 10th session with 100% feedback. During the remaining sessions, the intervention will include 3,000 steps, but the feedback will be gradually tapered off starting with the 11th session.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham real-time gait biofeedback
Description: The Sham RTGBF interventions will include eighteen step gait training sessions. The intervention will gradually increase to 3,000 steps at the 9th and 10th session with 100% feedback. During the remaining sessions, the intervention will include 3,000 steps, but the feedback will be gradually tapered off starting with the 11th session.
Study: NCT05582941

Intervention type: OTHER
Intervention: No intervention will be performed.
Description: No intervention will be performed.

Intervention type: OTHER
Intervention: No intervention will be performed.
Description: No intervention will be performed.
Study: NCT04917055

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ropivacaine 0.25% with epinephrine and 6mg dexamethasone
Description: Regional Nerve block behind the knee for posterior knee pain following total knee arthroplasty using ultrasound guidance, to be done distally between femoral chondyles

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Injection of Saline behind knee using ultrasound guidance
Study: NCT05582941

Intervention type: OTHER
Intervention: No intervention will be performed.
Description: No intervention will be performed.
Study: NCT04382378

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: neuromuscular electrical stimulation
Description: application of an electric current through electrodes placed on the skin over the targeted musclesto induce skeletal muscle contractions
Study: NCT06263153

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study: NCT06263153

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study: NCT06038201

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: LAMS placement for cholecystostomy
Description: The EUS-guided cholecystostomy entails placing a 10 mm x 10 mm or 10mm x 15mm Electrocautery-Enhanced LAMS for direct cholecystoscopy with a transnasal gastroscope. Then, the cholecystostomy will be performed with an echoendoscope, assisted by fluoroscopy to allow the puncturing of the gallbladder form either the duodenal bulb (cholecysto-duodenoscopy) or the gastric antrum (cholecysto-gastrostomy). Subsequently, from the most optimal anatomic point it will be tutored with a 10mmx10mm or 10mm x 15mm LAMS to create anastomosis between the structures. Then, the stone clearance will be performed by endoscopy (basket catheters) or by cholangioscopy (mechanical lithotripsy with or without basket catheters).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic cholecystectomy
Description: A laparoscopic biliary exploration along with an elective laparoscopic cholecystectomy will be performed by experienced laparoscopic surgeons (over 100 laparoscopic procedures yearly) by three or four-trocar technique with transection of the cystic duct and artery.