TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04922710

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based aerobic exercise
Description: Guidelines for exercise programming (ACSM, 2018) will be followed including a warmup and cool down, progressive and gradual increments in duration, and instruction regarding avoidance of physical activity related injury. The exercise group will receive moderate to vigorous intensity aerobic exercise for 60 minutes per day, three times a week, for 12 weeks. Participants who are unable to do a 60-minute session would instead complete it in two 30-minute sessions. The prescribed intensity will be based on estimated heart rate reserve, calculated using resting heart rate and age-adjusted heart rate maximum (220-age in years). Participants will maintain a minimum heart rate from their specific calculation that will be monitored by Polar Heart Rate straps.
Study: NCT05153863

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: C Scope Visualization System
Description: The C Scope Visualization System is indicated to be used by a trained physician to provide illumination and visualization in arthroscopic procedures of an interior cavity of the body through a surgical opening.
Study: NCT06229210

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lumateperone
Description: Lumateperone 42 mg capsules administered orally, once daily
Study: NCT04628767

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tissue biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: Given IV
Study: NCT06350006

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-A1904; Adebrelimab
Description: SHR-A1904 combined with Adebrelimab: SHR-A1904+ Adebrelimab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-A1904; CAPOX; Adebrelimab
Description: SHR-A1904 combined with Adebrelimab and CAPOX (Capecitabine, Oxaliplatin)
Study: NCT04800094

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Investigational Liver Fat Quantification Software
Description: All subjects enrolled in this study will undergo two abdominal ultrasound examinations using the investigational Liver Fat Quantification feature on the Philips EPIQ Ultrasound System. In addition, all subjects will also undergo one MRI-PDFF examination according to the clinical standard of care.
Study: NCT04598841

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: supplement nutritional supporting
Description: Special medical formula for the purpose of formula food
Study: NCT05376189

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: 400 IU
Description: An Oral Vitamin D3 400 IU will be given once daily for a total of 8 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 5000 IU
Description: An Oral Vitamin D3 5000 IU will be given once daily for a total of 8 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 10000 IU
Description: An Oral Vitamin D3 10000 IU will be given once daily for a total of 8 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fixed Drug Combination
Description: Standard Tuberculosis Regimen in a form of Fixed Drug Combination (FDC) given for Spondylitis Tuberculosis.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fixed Drug Combination
Description: Standard Tuberculosis Regimen in a form of Fixed Drug Combination (FDC) given for Spondylitis Tuberculosis.
Study: NCT04628767

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT
Study: NCT04596514

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: REBOA
Description: Resuscitative endovascular balloon occlusion of the aorta (REBOA)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: usual procedure according to guidelines
Description: Treatment as described in the guidelines from the European Resuscitation Council, the Norwegian Resuscitation Council, and other local national guidelines

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: usual procedure according to guidelines
Description: Treatment as described in the guidelines from the European Resuscitation Council, the Norwegian Resuscitation Council, and other local national guidelines
Study: NCT05376189

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fixed Drug Combination
Description: Standard Tuberculosis Regimen in a form of Fixed Drug Combination (FDC) given for Spondylitis Tuberculosis.
Study: NCT05561543

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Peppermint oil
Description: Peppermint oil

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06633328

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD7 CAR-T cells injection
Description: CD7 CAR T cells treat patients with severe aplastic anemia
Study: NCT04628767

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin Hydrochloride
Description: Given Iv

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin Hydrochloride
Description: Given Iv

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine Hydrochloride
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methotrexate
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pegfilgrastim
Description: Given via injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pegfilgrastim
Description: Given via injection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Therapeutic Conventional Surgery
Description: Undergo surgery

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic Conventional Surgery
Description: Undergo surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Therapeutic Conventional Surgery
Description: Undergo surgery

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vinblastine Sulfate
Description: Given Iv
Study: NCT04820036

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Insulin Resistance
Description: Insulin resistance: Fasting glucose and insulin will also be measured to calculate Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), as a surrogate of IR

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Quality of Life Assessment
Description: Quality of life will be assessed using the Chronic Liver Disease Questionnaire.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Liver Function Test
Description: EUS-guided liver biopsy and portal pressure gradient measurement

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Radiologic features of NASH
Description: Controlled attenuation parameter (CAP) and liver stiffness scores assessed by transient elastography (TE)

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Serologic features of NASH
Description: Laboratory value assessment of alanine aminotransferase (ALT), liver chemistries, platelet counts, albumin and calculated NAFLD Fibrosis Score (NFS).
Study: NCT06032572

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: VRS100 robotic-assisted PCI
Description: The VRS100 is intended for use in the remote delivery and manipulation of guidewires and rapid exchange balloon/stent catheters, and remote manipulation of guide catheters during percutaneous coronary intervention (PCI) procedures.
Study: NCT04628767

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vinblastine Sulfate
Description: Given Iv
Study: NCT04929678

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Braive™ Growth Modulation System (Braive™ GMS)
Description: The Braive™ GMS is designed as a growth-modulation, non-fusion technique, which utilizes patients' remaining growth potential to limit further progression of the curve, to provide correction of the thoracic spine, and allow continued growth while maintaining mobility.~The system consists of the following components: Braid, Fixed Angle Screws (FAS), Plate, and Break-Off Set Screw.
Study: NCT06524284

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Releaf
Description: 10 days/35 minutes per day EVNS (non-invasive electrostimulation) treatment on lower legs and feet by the subject or its caregiver after instruction by the podiatrist.
Study: NCT06633328

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Allogeneic hematopoietic stem cell transplantation
Description: In this study, Allogeneic hematopoietic stem cell transplantation is used as a bridge therapy to CD7 CAR T cells infusion to treat patients with severe aplastic anemia
Study: NCT06032572

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Manual PCI
Description: Use the traditional technique of manually advancing intracoronary guidewires, balloons, and stents at the patient's tableside.
Study: NCT05518123

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimegepant
Description: Rimegepant 75 mg Oral Disintegrating Tablet (ODT) taken every other day during Double-blind Treatment (DBT) phase
Study: NCT05856032

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acapella device
Description: Acapella is one of the Oscillatory Positive Expiratory Pressure (OPEP) device used in mobilization of peripheral secretions to the central trachea. It consists of a mouth piece and metal strip that is attached to a magnet which oscillates upon exhalation of the patient into the device results in oscillations. This helps in generating positive expiratory pressure (PEP) and oscillations of the magnetic ball assist in mucus collection and expectoration. Pulmonary functions are greatly reduced in patients undergone CABG surgery due to prolong effects of anaesthesia and muscle relaxants administered prior to surgery.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Treatment
Description: Conventional chest physiotherapy techniques
Study: NCT06633354

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD5 CAR T-cells
Description: Each subject receive CD5+ T-ALL Targeted CAR T-cells by intravenous infusion
Study: NCT05191771

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neovis Total Multi
Description: 1 drop in each eye, 4 times per day

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Systane Balance
Description: 1 drop in each eye, 4 times per day
Study: NCT06393829

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Applying the Early Mobilization Program
Description: A mobilization intervention based on the level of function (LOF) ( i.e. patients should be assessed for mobilization status within 24 hours of admission; mobilization should occur at least three times a day, and mobility should be progressive and scaled, tailored to the patient's abilities); The frequency of patient mobilization (primary outcome) will be assessed 20 weeks before implementation, during the 20 weeks of implementation and 20 weeks after the end of implementation (60 weeks in total).
Study: NCT05011565

Intervention type: OTHER
Intervention: Demographic and Clinical Characteristics, Maximal Exercise Capacity, Submaximal Exercise Capacity, Hemodynamic Parameters, Muscle Strength, Muscle Oxygenation, Vascular Function
Description: Demographic and Clinical Characteristics, Maximal Exercise Capacity, Submaximal Exercise Capacity, Hemodynamic Parameters, Muscle Strength, Muscle Oxygenation, Vascular Function
Study: NCT06634394

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: APVO436
Description: Infusion drug administered as a 4 hour infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Oral tablet given on days 1 through 22, of a 28 day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Intravenous infusion given on days 1-8 of a 28 day cycle
Study: NCT06632431

Intervention type: OTHER
Intervention: Endometrial cancer (EC)
Description: Endometrial cancer (EC) who underwent surgical staging (total hysterectomy and bilateral salpingo-oophorectomy) Histopathological slides for these cases will be reexamined and staged according to both the Federation of Gynecology and Obestetrics (FIGO) 2009 and updated Federation of Gynecology and Obestetrics (FIGO) 2023 endometrial staging systems. Upstaging refers to reclassification to a higher stage in the FIGO 2023 system compared to Federation of Gynecology and Obestetrics (FIGO)2009, while downstaging is the opposite.~All patients underwent lymph node dissection except those with Stage IA-Grades I and II endometrioid endometrial cancer and tumor size \<2 cm.
Study: NCT06584422

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empower@Home: An online cognitive-behavioral therapy self-care program for geriatric depression
Description: Empower@Home is an online self-help intervention based on cognitive behavioral therapy principles designed to treat depressive symptoms in older adults. The intervention has three components: 9 interactive self-paced online sessions, printed workbook that goes along the online sessions for exercises and homework, and telephone coaching by a trained staff from a social service agency serving older adults. The online sessions contain entertainment elements in the form of a character-driven story of a homebound older adults, video-based psycho-educational content, voice-over instructions, interactive exercises, and weekly home practice assignments.

Intervention type: OTHER
Group type: OTHER
Intervention: Telephone friendly visits
Description: Participants in the waitlist control group will receive attention control through biweekly telephone-friendly visitors. Trained project staff will call participants to provide companionship, emotional support, and a friendly conversation. In addition, the callers will conduct a biweekly assessment of depressive symptoms using the patient health questionnaire (PHQ-9), to mirror the biweekly in-app PHQ-9 assessments with the experimental group.
Study: NCT04707781

Intervention type: DIAGNOSTIC_TEST
Intervention: chest CT
Description: assessment of interstitial lung disease using chest CT

Intervention type: DIAGNOSTIC_TEST
Intervention: chest CT
Description: assessment of interstitial lung disease using chest CT
Study: NCT05297578

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 24-Valent Pneumococcal Conjugate Vaccine
Description: 0.5 ml dose of VAX-24 will be administered into the deltoid muscle at Day 1

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 24-Valent Pneumococcal Conjugate Vaccine
Description: 0.5 ml dose of VAX-24 will be administered into the deltoid muscle at Day 1

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 24-Valent Pneumococcal Conjugate Vaccine
Description: 0.5 ml dose of VAX-24 will be administered into the deltoid muscle at Day 1

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pneumococcal 20-valent Conjugate Vaccine
Description: 0.5 ml dose of Prevnar 20 will be administered into the deltoid muscle at Day 1
Study: NCT05903014

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: n-acetylcysteine
Description: we give 3600 mg n-acetylcysteine divided twice a day, for 12 weeks

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Enhancement Therapy
Description: Motivational enhancement therapy with individual and/or group session to maintain and increase subject's motivation to quit smoking

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Motivational Enhancement Therapy
Description: Motivational enhancement therapy with individual and/or group session to maintain and increase subject's motivation to quit smoking
Study: NCT05811897

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Managed Online Treatment
Description: Self-help online cognitive-behavioural therapy focusing on post-traumatic stress, sleep and mood. The content is divided into three modules :~* Coping with my trauma: psychoeducation about PTSD, cognitive restructuring prolonged exposure to avoided situations and memories (14 sessions)~* Sleeping better: psychoeducation about, sleep management strategies (restriction of time in bed, stimulus control, sleep hygiene education), Imagery Rehearsal Therapy (10 sessions)~* Improving my mood: psychoeducation about depression, behavioural activation; relaxation and mindfulness exercises; problem-solving strategies (6 sessions)~A small portion of material is unlocked each week, and access to one module will be accessible after the completion of a previous one. Access to the online material will be unlimited in time. Participants complete self-report questionnaires after each module, the platform then provides feedback and suggests corresponding modules.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Therapist-Assisted Online Treatment
Description: Same online intervention. Supervised graduate psychology students will provide brief regular weekly contacts for up to 30 weeks by video chat or phone, according to the participant's preference.
Study: NCT04540406

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NBT-NM108
Description: Taken in the form of drinks four times a day (before each main meal and 2 hours after dinner) for 28 days. Each drink is prepared by mixing one sachet (30 g) with 500 ml of water.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care Only
Description: Control group will also follow the same schedule except they will drink the same volume of water without NBT-NM108.
Study: NCT05735041

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-domain cognitive digital therapy
Description: Patients in the cognitive digital therapy group received multi-dimensional targeted cognitive function training electronically, involving attention, memory, executive function, thinking, processing speed and perception. The system will adjust the training difficulty and training plan adaptively according to the patient's current training time and performance, and train the patient's weak cognitive ability as far as possible. The patients had the same total amount of training each day.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Basic cognitive therapy
Description: The training content of the positive control group was cognitive training tasks with weak difficulty or no difficulty change. The patients underwent cognitive function training with fixed programs, including 15 training items, and the internal difficulty of the training items remained constant without change. The system presents the training content randomly according to the training scheme. The patients had the same total amount of training each day.
Study: NCT05518123

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo with every other day dosing during DBT phase
Study: NCT05351606

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tobacco Use Cessation Counselling Sessions
Description: Counseling sessions will be given in person
Study: NCT05176730

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness meditation
Description: Similar to the information included in arm/group descriptions
Study: NCT06382259

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Movement breaks
Description: Stretching and mobility-based exercises lasting 1-minute each performed 4 times per day on two consecutive days.
Study: NCT04963335

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exergame Training
Description: The individualized exergames were designed for a pressure sensitive plate connected to a personal computer and a frontal screen. The pressure-sensitive plate allows a precise analysis of the user's movements. This concurrent motor-cognitive training aims to improve motor and cognitive functions in an ecological valid setting. The cognitive functions are triggered by specific stimuli in the game scenarios. The video games are controlled via specific (whole body) movements as steps, weight shifting, jumps, and arm movements. The training focus is mainly on multi-tasking, balance and coordination as well as executive functions and attention. Furthermore, the meaningful games (colorful and appealing visuals) were designed to motivate the players to move. As the exergame will automatically adapt (individual progression) during play time, participants are challenged at their individual motor and cognitive level.
Study: NCT06422572

Intervention type: OTHER
Intervention: No Intervention
Description: No Intervention
Study: NCT06427148

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The biofeedback-assisted VR game Golden Breath
Description: The biofeedback-assisted VR game Golden Breath that we presented in this study was designed to meet children's healthcare needs quickly and efficiently while reducing pain and fear during medical procedures in the pediatric population. Golden Breath u
Study: NCT05351606

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tobacco Use Cessation Counselling Sessions
Description: Counseling sessions will be given in person

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupropion
Description: Given orally
Study: NCT06083662

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neratinib Maleate
Description: * neratinib 240mg po daily~* herzuma 8mg/kg (loading) --\> 6mg/kg q3w