TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05607290

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Cognitive-Behavioral Treatment
Description: 12 sessions of Cognitive-Behavioral Treatment for Alcohol Use Disorder
Study: NCT06331923

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous glucose monitoring (CGM) device
Description: Continuous glucose monitoring (CGM) will be prescribed by the attending physician for at least 6 hours before surgery. The supervising nurse will educate the patient and their family on the correct wearing and connection of the CGM device. The calibration frequency and interval of glucose monitoring devices before and after surgery should be determined according to institutional treatment guidelines and the requirements of the monitoring device used. Intraoperative glucose calibration should be done immediately upon entering the operating room, immediately after skin incision, every 2 hours after skin incision, and at the end of wound closure. Glucose monitoring should be continued until the 7th day after surgery or discharge.
Study: NCT05274672

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nitrofurantoin
Description: Prophylactic postoperative antibiotic use

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cephalexin
Description: Prophylactic postoperative antibiotic use

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sulfamethoxazole Trimethoprim Combination
Description: Prophylactic postoperative antibiotic use

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ciprofloxacin
Description: Prophylactic postoperative antibiotic use

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Holmium Laser Enucleation of prostate
Description: Endoscopic transurethral Holmium Laser enucleation of enlarged prostate followed by morcellation of prostatic tissue

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Holmium Laser Enucleation of prostate
Description: Endoscopic transurethral Holmium Laser enucleation of enlarged prostate followed by morcellation of prostatic tissue
Study: NCT04958252

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1569912
Description: BI 1569912

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT04763343

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Hydrochloride
Description: Ketamine hydrochloride will be given as an intravenous infusion using a standard regimen given in most studies conducted: 0.5 mg/kg over 40 minutes. Ketamine infusions will be given every other day until either the subject reports clinician rated Scale for Suicidal Ideation (SSI) score of\<4, and \>50% decrease from baseline, and clinical assessment of patient not being suicidal for three consecutive pre-infusion ratings, or a maximum of six infusions have been given over the course of 2 weeks, or they have been discharged from the inpatient unit.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Subjects randomized to placebo will be administered a saline (0.9% sodium chloride) drip for 40 minutes. Saline placebo infusions will be given every other day until either the subject reports clinician rated Scale for Suicidal Ideation (SSI) score of\<4, and \>50% decrease from baseline, and clinical assessment of patient not being suicidal for three consecutive pre-infusion ratings, or a maximum of six infusions have been given over the course of 2 weeks, or they have been discharged from the inpatient unit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CAMS Therapy
Description: CAMS weekly sessions will also be started immediately as an inpatient at the start of the study while receiving ketamine or saline. CAMS will be continued weekly after the patient is discharged and followed up as an outpatient. Weekly CAMS sessions will be terminated after the subject, as an outpatient, has three consecutive outpatient CAMS sessions with an overall risk \< 2 (# 6 on the SSF Core Assessment) along with a positive response regarding their thoughts/feelings and clinician indicating behavioral stability (suicidal behavior).

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: CAMS Therapy
Description: CAMS weekly sessions will also be started immediately as an inpatient at the start of the study while receiving ketamine or saline. CAMS will be continued weekly after the patient is discharged and followed up as an outpatient. Weekly CAMS sessions will be terminated after the subject, as an outpatient, has three consecutive outpatient CAMS sessions with an overall risk \< 2 (# 6 on the SSF Core Assessment) along with a positive response regarding their thoughts/feelings and clinician indicating behavioral stability (suicidal behavior).
Study: NCT05356715

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound guided bilateral ESBP
Description: Patients in group A will be positioned in the lateral position , ESPB will be done under complete aseptic conditions , using , linear ultrasound probe(Philips HD11XE Ultrasound System) , to locate the ESP at the level of the fifth dorsal vertebrae , 22 G spinal needle will be used to inject 20 ml of 0.25% of bupivacaine in the ESP bilaterally, block will done by an expert anesthesiologist , who will not be included in the data collection

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound guided bilateral ESBP
Description: Patients in group A will be positioned in the lateral position , ESPB will be done under complete aseptic conditions , using , linear ultrasound probe(Philips HD11XE Ultrasound System) , to locate the ESP at the level of the fifth dorsal vertebrae , 22 G spinal needle will be used to inject 20 ml of 0.25% of bupivacaine in the ESP bilaterally, block will done by an expert anesthesiologist , who will not be included in the data collection
Study: NCT06459726

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: shi style mobilization
Description: Step 1 soothing tendon stepTherapist will aerate patient's neck 3 to 6 times.Step 2 moblization step Therapist will apply low velocity small amplitude oscillatory movement without thrust. Head will be in 45 degrees of flexion or extension. Repeat this for 3 to 6 times. Then distraction force is applied to the cervical. Step 3 dredging collateral step Therapist holds thenar and hypothenar muscles of patient's hand on affected side and gently shook the upper limb ebb and flow with small shaking and high frequency. Repeat the procedure 3 times 6 sesions over 2 weeks for 20minutes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SNAGS
Description: Patient will receive sustained natural apophyseal glides as described by brian mulligan. Patient position will be upright sitting when therapist will apply a sustained passive assesory glide while patient moves actively through available physiological range of motion in the direction in which symptoms are produced. the headache SNAG technique will be performed with the patient sitting on a chair in the erect posture. The therapist will handle C2 spinous process with the middle phalanx of one hand. With the other hand, he will perform ventral gliding on C2 for 10 repetitions holding for 10 seconds in each glide with a rest time of 30 seconds in between. Patient will be asked to report dizziness or any other symptom after procedure. If patient reports symptom then angle of application is changed to ensure symptom free treatment in all patientsNumber of repetitions are increased gradually from 6 to 10 and end physiological movement is maintained for 10second
Study: NCT05539482

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community-based Health Education based on core intervention package
Description: Community-based Health Education will potentially include the following three components:~1. A manual of emergency preparedness and self-protection against COVID-19 infection. The main content will include hand washing, mask wearing and social distancing guidelines.~2. Early testing. Participants will be trained on how to recognize the early symptoms of COVID-19 and appropriate practice to take in a response, and they will be provided with testing resources.~3. Knowledge of vaccines and their benefits and resources for vaccination.~Collaborators should design and implement health programs based on the core intervention package.
Study: NCT06040333

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Dynamic Neuromuscular Stabilisation Exercise
Study: NCT04308512

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Care4AD system
Description: Eligible subjects will be randomized to intervention, IG, and control groups, CG, with ratio of 1:1 and will be assessed at baseline and six months. All reminders will be activated in the intervention group and de-activated in the control group. Essential ADL tasks will be preprogrammed by our care coordination expert for the IG. Patients and their caregivers in the IG will be also able to schedule additional tasks.
Study: NCT06293625

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Folfox
Description: Folfox chemotherapy (folinic acid, fluorouracil and oxaliplatin) for 6 weeks (3 courses) before surgery.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgery
Description: Experimental arm: Surgery should take place 21 days after the last dose of neoadjuvant chemotherapy Control arm: upfront surgery as soon as possible

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Experimental arm: Surgery should take place 21 days after the last dose of neoadjuvant chemotherapy Control arm: upfront surgery as soon as possible
Study: NCT05233696

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab-paclitaxel
Description: All patients are encouraged to receive nab-paclitaxel 100 mg/m2 IV D1 and D8 every 21 days (in combination with pembrolizumab) for at least 4-6 cycles per institutional standards and treating physicians' recommendations.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel can be substituted for nab-paclitaxel at the discretion of the treating physician 80 mg/m2 IV D1 and D8 every 21 days.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: The treating radiation oncologist will select 1-4 sites of metastatic disease to target with radiation. All sites of disease may be targeted with radiation. Sites of metastatic disease planned to be biopsied should not be radiated.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Patients will receive pembrolizumab 200 mg D1 every 21 days.
Study: NCT06454019

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Phone Outreach
Description: Phone outreach to individuals losing Medicaid and auto-enrolled into Covered California plan to nudge them to act

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Notice
Description: Standard notification letter without phone outreach to individuals losing Medicaid and auto-enrolled into Covered California plan to nudge them to act
Study: NCT06473948

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX001899
Description: Participants will receive JMKX001899 500mg tablet, orally once on Day 1
Study: NCT06530589

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tupler's Technique
Description: Patient will wear diastasis rehab splint and will follow Tupler's techniqe protocol for 6 weeks. In the first 2 weeks both elevator and contracting exercises will be performed and after 2 weeks in the 3rd week only contracting exercises will be perform and for these exercises we divide abdomen into 6 floors and will patient have to contract her tummy towards the 3rd to 5th floor in first week, towards the 4th to 5th floor in 2nd week and from 5th to 6th floor in the 3rd week. in the wek 4 to week 6 head lifts will also be started along with contracting exercises from 5th to 6th floor.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Exercises
Description: The traditional treatment includes traditional abdominal exercises that patient will be perform for 6 weeks and three times per week with 15 repetitions of each exercise. These exercises includes posterior pelvic tilt' static abdominal contractions', reverse sit up exercise, kegals, russian twist , trunk twist and reverse trunk twist.
Study: NCT04659226

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Blood sampling for microRNA testing
Description: Blood samples will be collected and analyzed for the microRNA profile by means of microfluidic cards
Study: NCT05362643

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Manual acupuncture on acupoint Tai Xi(KI3), bilateral;Sanyinjiao (SP6), bilateral; Zusanli (ST36), bilateral; Shenmen (HT7) unilateral, in the arm without arteriovenous fistula;Guan Yuan (CV4), unilateral, attempt to achieve De qi sensation. After generating needling sensation, needles were manipulated for one minute, every ten minutes during needle retention (20 minutes), using Sterilized stainless steel needle (0,25x25mm; Tewa, asia-med GmbH).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham Acupuncture
Description: Manual acupuncture performed as superficial needling (5mm depth) on non-acupuncture points without an attempt to achieve De qi sensation and without stimulation, lasting 20 minutes, using Sterilized stainless steel needle (0,25x25mm; Tewa, asia-med GmbH).
Study: NCT06473948

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX001899
Description: Participants will receive JMKX001899 750mg tablet, orally once on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JMKX001899
Description: Participants will receive JMKX001899 1000mg tablet, orally once on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive JMKX001899 matching placebo, tablet, orally once on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive JMKX001899 matching placebo, tablet, orally once on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive JMKX001899 matching placebo, tablet, orally once on Day 1
Study: NCT05599191

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-5937
Description: Oral administration of BLU-5937 Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-5937
Description: Oral administration of BLU-5937 Tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral administration of matching placebo for BLU-5937 Tablets
Study: NCT05306977

Intervention type: DEVICE
Group type: OTHER
Intervention: Open-label accelerated 1 Hz repetitive transcranial magnetic stimulation
Description: Patients will receive a 5-day course of accelerated 1 Hz rTMS (8x session x 600 pulses/session) to the right intraparietal sulcus. Subjects will receive a continuous train of 1 Hz stimulation. They will receive a total of 600 pulses per train. Trains will be separated by \~50 min rest intervals.
Study: NCT06069908

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Complex Decongestive Treatment
Description: Complex Decongestive Treatment (manual lymph drainage, skin care, special exercises, compression) approach. It will be applied 5 days a week for 3 weeks

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Complex Decongestive Treatment
Description: Complex Decongestive Treatment (manual lymph drainage, skin care, special exercises, compression) approach. It will be applied 5 days a week for 3 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Complex Decongestive Treatment
Description: Complex Decongestive Treatment (manual lymph drainage, skin care, special exercises, compression) approach. It will be applied 5 days a week for 3 weeks

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham transcutaneous vagus nerve stimulation
Description: In sham transcutaneous vagus nerve stimulation application, the device electrode will be placed in the superior scapha region of the outer ear, where the vagus nerve has no innervation, and no current will be given.Complex Decongestive Therapy and sham transcutaneous vagus nerve stimulation.It will be applied 5 days a week for 3 weeks.
Study: NCT05485272

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Silver Diamine Fluoride combined with Potassium Iodide.
Description: Riva Star, Silver diamine fluoride 38% and potassium iodide, SDI, Bayswater, Australia.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Silver Diamine Fluoride.
Description: A clear liquid that combines the antibacterial effects of silver and the remineralizing effects of fluoride.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High-Viscosity Glass Ionomer.
Description: A Glass Hybrid material.
Study: NCT05905211

Intervention type: OTHER
Intervention: Observational Tests
Description: The Berg Balance Scale was used to evaluate the balance levels, the Timed Up and Go Test was used to evaluate the functional mobility levels, and the Functional Independence Scale was used to evaluate the activities of daily living. The World Health Organization Quality of Life Instrument-Older Adults Module (WHOQOL-OLD) was used to evaluate the quality of life, the Fear of COVID-19 Scale was used to evaluate the COVID-19 fear levels, the Geriatric Depression Scale was used to evaluate the symptoms of depression.

Intervention type: OTHER
Intervention: Observational Tests
Description: The Berg Balance Scale was used to evaluate the balance levels, the Timed Up and Go Test was used to evaluate the functional mobility levels, and the Functional Independence Scale was used to evaluate the activities of daily living. The World Health Organization Quality of Life Instrument-Older Adults Module (WHOQOL-OLD) was used to evaluate the quality of life, the Fear of COVID-19 Scale was used to evaluate the COVID-19 fear levels, the Geriatric Depression Scale was used to evaluate the symptoms of depression.
Study: NCT04829955

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Eccentric manual resistance training
Description: Eccentric bodyweight resistance training

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Concentric manual resistance resistance training
Description: Concentric bodyweight resistance training
Study: NCT05504148

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: crocin
Description: Take saffron total glucosides tablets for 8 days during each chemotherapy (started on the 1st day before radiotherapy/chemotherapy), 4 tablets/time, 3 times a day.
Study: NCT06069908

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous Auricular Vagus Nerve Stimulation
Description: Transcutaneous vagus nerve stimulation will be applied in addition to Complex Decongestive Therapy.It will be applied 5 days a week for 3 weeks.
Study: NCT05504148

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Take placebo piece during for 8 days during each chemotherapy (started on the 1st day before radiotherapy/chemotherapy), 4 tablets/time, 3 times a day
Study: NCT06069908

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Exercise
Description: Patients will undergo lymphedema-specific exercises 5 days a week for 3 weeks.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Exercise
Description: Patients will undergo lymphedema-specific exercises 5 days a week for 3 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Patients will undergo lymphedema-specific exercises 5 days a week for 3 weeks.
Study: NCT05516108

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: The mindfulness intervention includes 14 daily 20-minute audio lessons plus brief daily practice prompts. Lessons train specific meditation techniques through didactic explanation and guided practice. Based on the Unified Mindfulness system, lessons train 3 mindfulness skills: concentration, sensory clarity, and equanimity. Concentration, a state of stable attention on the intended target, enables participants to monitor present-moment physical and emotional body experiences. Sensory clarity, the monitoring of momentary experiences, involves detecting subtle sensations and discriminating between different experiences. Equanimity, an attitude of acceptance toward momentary experiences, is trained through 3 strategies: (a) body relaxation, (b) mental welcoming, and (c) a gentle tone of voice. Practice prompts build on the skills trained in each lesson, encouraging participants to practice brief moments of mindful awareness, mindfulness while doing daily tasks, or formal meditation.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Coping
Description: The coping intervention includes 14 daily 20-minute audio lessons plus brief daily practice prompts. Lessons train specific coping techniques through didactic explanation and guided practice. Lessons train coping skills (reflection, reappraisal, and problem solving) without encouraging focus on or acceptance of present experience (i.e., mindfulness skills). Participants are instructed to: (1) reflect and let their minds drift, (2) reframe or reappraise past and anticipated events, and (3) analyze and solve personal problems. Practice prompts build on the skills trained in each lesson, encouraging participants to take brief reflection breaks or to practice reappraisal or problem-solving skills.
Study: NCT06350227

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: the absorbable hemostat and suture
Description: The hemostasis method of the experimental group is to use both the absorbable hemostat and suture.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: electrocoagulation and suture
Description: The active comparator group is to use electrocoagulation and suture simultaneously to stop bleeding.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: suture
Description: The placebo comparator is to use suture alone for hemostasis.
Study: NCT04708652

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05169307

Intervention type: DRUG
Intervention: CPX-351
Description: This is a retrospective, non-interventional, observational study. No study drug will be administered in this study.