TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04614194

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Oral. Tablets should be taken at the same times every day, with or without food.
Study: NCT05849389

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vosoritide
Description: Vosoritide administered daily via subcutaneous injection for 12 months using the FDA approved weight-based dosing band strategy for achondroplasia.
Study: NCT05764759

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking cessation e-visit
Description: electronic visits (e-visits) for smoking cessation

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: Information about the state quitline and about the importance of quitting smoking and a recommendation to contact one's PCP to schedule a medical visit to discuss quitting smoking.
Study: NCT05693896

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Centering Appetite
Description: A digital treatment of Appetite Awareness Treatment (AAT) and behavioral weight loss treatment (BWL) over 6 months, delivered remotely using Zoom. The goal of AAT is to enable participants to be able to relearn their stomach's hunger signals and begin to obey and monitor functions of satiety. AAT has been successful in helping participants diagnosed with Binge Eating Disorder (BED) and bulimia nervosa reduce binge eating, overeating, urges to eat in response to non-appetite stimuli, and prevent weight gain.
Study: NCT06210919

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TRTP-101
Description: Intradermal injection of the each of four sites
Study: NCT05389631

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT04990427

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CLBS201
Description: 1 x 10\^6 to 300 x 10\^6 autologous CD34+ cells
Study: NCT05571865

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Probiotic
Description: Oral administration of a probiotic

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Probiotic
Description: Oral administration of a probiotic
Study: NCT04939376

Intervention type: PROCEDURE
Intervention: IVF
Description: In vitro fertilization

Intervention type: PROCEDURE
Intervention: IVF
Description: In vitro fertilization
Study: NCT04730648

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PCSK9 inhibitor
Description: For newly diagnosed ACS patients with diabetes, multivessel occlusion, or recurrent ACS attack, who are willing to accept PCSK9 inhibitor injection.
Study: NCT05923827

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Omnipod 5 System
Description: The Omnipod 5 system is a tubeless patch pump that receives glucose values and trend data from the glucose sensor every 5 minutes, automatically calculates insulin dose, and sends delivery commands to the Pod for the delivery of insulin.
Study: NCT06384313

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: butyrate/hexanoate-enriched triglycerides
Description: The oils are consumed two times a day for 24 weeks (six months).

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: butyrate/hexanoate-enriched triglycerides
Description: The oils are consumed two times a day for 24 weeks (six months).
Study: NCT06516991

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Temporal Interference Stimulation
Description: Specific electrode sites are customized for the subject through magnetic resonance scanning, the deep nucleus cluster to be stimulated-nucleus accumbens is calibrated through electric field simulation before treatment, and the stimulation target can be accurately positioned by stimulating the specific electrode sites of the subject during treatment.~During the treatment period, all subjects were treated with a fixed time interference stimulation (TI) device at a frequency of 30 minutes twice a day, 5 days a week, for a total of 10 treatments. The output current intensity during treatment is 3.64 mA+4.36 mA.
Study: NCT05623033

Intervention type: OTHER
Intervention: The study is an observational study without intervention
Description: The study is an observational study without intervention

Intervention type: OTHER
Intervention: The study is an observational study without intervention
Description: The study is an observational study without intervention
Study: NCT05340231

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TACE protocol
Description: Transarterial infusion chemotherapy: Oxaliplatin(85mg/m\^2)+Raltitrexed(3mg) Chemoembolization: Lipiodol emulsion (lipiodol 10ml+ Oxaliplatin 85mg +Lidocaine 1ml)，The endpoint for embolization was defined as stagnation of blood flow of the posterior mesenteric artery.~Intervention cycle：4W; Treatment times: 2. followed by mFOLFOX6

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neoadjuvant Chemotherapy
Description: mFOLFOX6, Q2W
Study: NCT04975087

Intervention type: OTHER
Intervention: Patients group
Description: Patients will complete the mentioned questionnaires.
Study: NCT05467813

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mirror therapy
Description: The mirror therapy (MT) will be done with participants seated at a table. The affected upper-extremity (UE) will be placed behind the mirror and the unaffected UE in front of the mirror. Participants will be asked to do the same movements using both the unaffected and affected UE as possible. Each participant will practice two different MT protocols: unilateral mirror therapy (UMT) and bilateral mirror therapy (BMT). During UMT, the affected hand is static, while during BMT, the affected hand moves in an attempt to duplicate the unaffected hand as best as possible. The MT activities include gross motor movements, fine motor movements, and object manipulation.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: mirror therapy
Description: The mirror therapy (MT) will be done with participants seated at a table. The affected upper-extremity (UE) will be placed behind the mirror and the unaffected UE in front of the mirror. Participants will be asked to do the same movements using both the unaffected and affected UE as possible. Each participant will practice two different MT protocols: unilateral mirror therapy (UMT) and bilateral mirror therapy (BMT). During UMT, the affected hand is static, while during BMT, the affected hand moves in an attempt to duplicate the unaffected hand as best as possible. The MT activities include gross motor movements, fine motor movements, and object manipulation.
Study: NCT05379933

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote health coaching to improve self-care behaviors
Description: Participants will be asked to wear an activity tracker, complete brief surveys, and participate in weekly health coaching sessions remotely for 8 weeks
Study: NCT04849195

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT04778644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD
Description: Oral gel capsule CBD

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD
Description: Oral gel capsule CBD
Study: NCT06097078

Intervention type: DEVICE
Intervention: Eso-SPONGE®
Description: minimally invasive treatment and prevention of anastomotic leakages and perforations in the upper gastrointestinal tract (upper GIT)
Study: NCT05467813

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: augmented reality (AR)
Description: The training program provides goal-directed exercises designed to be adjustable in order to match the patient's ability to minimize compensatory movements. To ensure safety, the investigators will place a handrail in front of the participant for support. The goal-directed exercise includes balance training (i.e., weight shifting, standing on one leg), activities of daily living training (i.e., reaching), and cognitive enhancement (i.e., memory training). By using the AR system, participants can observe the real performance of motions and interaction between the body and the virtual environment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: augmented reality (AR)
Description: The training program provides goal-directed exercises designed to be adjustable in order to match the patient's ability to minimize compensatory movements. To ensure safety, the investigators will place a handrail in front of the participant for support. The goal-directed exercise includes balance training (i.e., weight shifting, standing on one leg), activities of daily living training (i.e., reaching), and cognitive enhancement (i.e., memory training). By using the AR system, participants can observe the real performance of motions and interaction between the body and the virtual environment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control therapy
Description: The control intervention will include practice of upper limb activities, balance activities, activities of daily living, and cognitive enhancement tasks. The protocols of the conventional therapy will be formulated by using occupational therapy techniques, such as neurodevelopmental techniques and functional task training. The therapy will be adapted to the participants' levels of motor deficits and their prioritized goals. The protocol will include affected arm exercise or gross motor training, muscle strengthening of the affected arm, fine motor or dexterity training, and functional tasks of daily life or compensatory techniques to alleviate functional deficits. The therapist will work with the participant to select functionally relevant tasks, such as picking up items from a box, lifting soft drink bottles, hanging clothes, and so on.
Study: NCT04928040

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Measurement of optic nerve sheath diameter
Description: The fluid challenge effects of optic nerve sheath diameter
Study: NCT06196749

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Perform distal radial arterial cannulation using modified ultrasound-guided dynamic needle tip positioning technique
Description: This study employs a modified ultrasound-guided dynamic needle tip positioning technique for distal radial arterial cannulation. The technique uses an ultrasound probe with two wires to create an acoustic shadow, improving needle tip visibility. Real-time dynamic tracking assists in precise needle placement within the distal radial artery through the nose-horn region. This method is used for coronary angiography and potential percutaneous coronary interventions, aiming to increase success rates and reduce complications like hematoma, nerve injury, and arterial spasm, thus enhancing safety and efficiency.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Palpation guided puncture
Description: Perform distal radial arterial cannulation under palpation guidance
Study: NCT04778644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral gel capsule placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral gel capsule placebo
Study: NCT04994275

Intervention type: OTHER
Intervention: no intervention, but presence of ID or not
Description: This is an observational study regarding patients admitted to undergo a major elective surgery supposed to last more than an hour. Investigators will analyzed the incidence of postoperative infections up to 90 days after surgery according to the preoperative iron status: iron deficiency (defined as a ferritin of less than 100 µg/L or \<300 µg/L And TSAT\<20%) or no iron deficiency
Study: NCT04352400

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nafamostat Mesilate
Description: administered intravenously as a continuous infusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: administered intravenously as a continuous infusion
Study: NCT05834452

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: The Epley Maneuver
Description: 5 step procedure where the patient:~1. Sits upright in a neutral position~2. Rotate 45° towards the affected side around the yaw axis and then ro-tate 135° backward around the pitch axis~3. Rotated 90° towards the unaffected side around the yaw axis~4. Rotate a further 90° toward the unaffected side around the yaw axis~5. Rotates back to an upright position with a 135° backward rotation around the pitch axis.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: The 360 Degree Maneuver
Description: 5 step procedure where the patient:~1. Sits upright in a neutral position~2. Rotate 45° towards the affected side around the yaw axis and then ro-tate 135° backward around the pitch axis~3. Rotate a further 90° backward around the pitch axis (total 225°)~4. Rotate a further 90° backward around the pitch axis (total 315°)~5. Rotate back to an upright position with an additional 45° backward rota-tion around the pitch axis (total 360°).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical rotational chair
Description: TRV chair

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical rotational chair
Description: TRV chair
Study: NCT04804566

Intervention type: OTHER
Intervention: This is a non-interventional study
Description: This is a non-interventional study

Intervention type: OTHER
Intervention: This is a non-interventional study
Description: This is a non-interventional study
Study: NCT06397443

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 5-day sailing activity
Description: * Sailing activity (4 h/die)~* Stretching exercises pre and post-sailing activity~* Post-activity debriefing
Study: NCT06570512

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: transcutaneous posterior tibial nerve stimulation
Description: Over three weeks, the TPTNS group underwent ten sessions of electrical stimulation along the course of the posterior tibial nerve behind the medial malleoli using cup electrodes, with a width pulse of 250 microseconds, and a frequency of 20 Hz. The TENS group used a sham device with the same parameters, but the electrodes were placed behind the lateral malleoli with underpowered amplitudes.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous posterior tibial nerve stimulation
Description: Over three weeks, the TPTNS group underwent ten sessions of electrical stimulation along the course of the posterior tibial nerve behind the medial malleoli using cup electrodes, with a width pulse of 250 microseconds, and a frequency of 20 Hz. The TENS group used a sham device with the same parameters, but the electrodes were placed behind the lateral malleoli with underpowered amplitudes.
Study: NCT05504291

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo aqueous humor and tissue sample collection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Examination Under Anesthesia
Description: Undergo imaging of the eye during EUA

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melphalan
Description: Given I-VITRE

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound Biomicroscopy
Description: Undergo UBM during EUA

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Given IV
Study: NCT06653764

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest physiotherapy and aerobic exercise training
Description: Chest Physiotherapy including Percussion, vibration and shaking; along with it aerobic exercises such as walking up and down stairs, bedside ambulation, step walking
Study: NCT06312579

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 12-week home based exercise
Description: Consistent with current physical activity recommendations for older adults, participants randomized in this arm will be prescribed 5 days/week of exercise, with seated cycling exercise performed on 3 days a week (Monday, Wednesday and Friday), and strength/balance exercise performed 2 days a week (Tuesday and Thursday).

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: 12-week standard of care
Description: Participants in this group will be provided with guidance on the current standard of care. This includes guidance that these patients should slowly increase ambulation with appropriately fitted footwear.
Study: NCT06388746

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BRIX3000®
Description: A gel that when applied to the tooth completely removes carious tissues in a chemo mechanical way without rotary instruments. It contains an enzyme that has bactericidal, bacteriostatic and anti-inflammatory properties and proteolytic properties that help soften and break down decayed tissue without destroying the underlying healthy collagen fibers.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Riva Star Aqua, SDI Limited, Australia
Description: A solution that contains 44,800 ppm F and 253,870 ppm Ag. It acts as a fluoride storage for the acid challenges, while inhibites demineralization of hydroxyapatite crystals and preserves collagen from degradation in demineralized tissues.
Study: NCT04601532

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser
Description: Catasyn™ Advanced Technology Hydrogel is a wound hydrogel that provides a moist wound environment. A moist wound environment is supportive to wound healing. SynePure™ Wound Cleanser is a non-cytotoxic wound cleanser for the removal of foreign material from epidermal and dermal wounds, burns, cuts, abrasions and minor irritations of the skin.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Silver Sulfadiazine
Description: Silver sulfadiazine, a sulfa drug, is used to prevent and treat infections in burn wounds.
Study: NCT05037695

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: empagliflozin 25 MG
Description: empagliflozin 25mg - daily
Study: NCT06125171

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tucidinostat, Apatinib
Description: Tucidinostat:~age≥18years, 30mg, po., biw, q4w; age≥10years，\<18years，0.5mg/kg, biw, q4w~Apatinib:~BSA≥1.2m\^2, 500mg, qd, q4w BSA\<1.2m\^2, 250mg, qd, q4w
Study: NCT06176430

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ferrous Sulfate Oral Product
Description: ferrous sulphate oral in the form of syrup

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Ferrous Sulfate Oral Product
Description: ferrous sulphate oral in the form of syrup
Study: NCT06235593

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-care Intervention
Description: The intervention will focus on self-care behavior of people with chronic diseases according to two distinct periods (through a longitudinal study - follow-up nursing interventions):~(i) baseline; and (ii) 4 months;
Study: NCT06598787

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BL-B01D1 for Injection
Description: Administration by intravenous infusion for a cycle of 3 weeks.
Study: NCT06651385

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote digital therapeutic exercise program
Description: Participants will be introduced to the digital therapeutic exercise program during Screening and Consent (Visit 0, V0). Participants will be provided with an orientation to the Vitala platform and assistance will be offered in the download and access to the application, as needed. The study team will ensure access has been obtained via the health care professionals' dashboard on the Vitala app. Information obtained in the assessments outlined above will inform the tailored exercise prescription to meet the participant's needs. Participants will be encouraged to complete a total of 150 minutes of remote exercise sessions each week for 12 weeks via the Vitala platform. Participants will receive daily notifications to remind them to complete their assigned daily exercises.
Study: NCT06660953

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block
Description: For ESP, high frequency linear ultrasound probe was planned transversely to the midline and spinous features were visualized. Cervical C7 and T7 vertebrae at the lower end of the scapula, which were accepted as landmarks, were determined and marked with a sterile surgical drawing pen. According to these landmarks, the USG probe was moved 2-3 cm laterally towards the points where kidney transplantation was planned at the T10 vertebral level, and the transverse parts, trapezius, latissimus dorsi, serratus and erector spina muscles were visualized. Using the block needle that can be visualized on USG with in-plane surgery, the skin, subcutaneous tissue and trapezius, latissimus dorsi, serratus and erector spina muscles were passed in a cranio caudal direction and the needle location was confirmed by hydrodissection with 2-5 ml of serum. The distribution of the block procedure and the spread of local anesthetic were linearly visualized with 10 ml bupivacaine and 10 ml 0.9% saline.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus Lumborum Block (QLB)
Description: The QL block II was done under aseptic technique, in lateral position with the side intended to block side up. A high frequency ultrasound linear probe covered in sterile sheath was placed anterior and superior to the iliac crest. The three anterior abdominal muscles were visualized. The external oblique muscle was followed posterolaterally until its posterior border was identified. Subsequently, the probe was tilted towards the attachment site of both the internal and external oblique muscles over the quadratus (QL) muscle until the midline of the thoracolumbar fascia was seen as a bright hyperechogenic line located between the posterior border of the quadratus lumborum muscle and the middle thoraco-lumbar fascia (anterior to latissiumus dorsi and erector spinae muscles). A 22-gauge Facet-tip SonoPlex needle of appropriate length estimated from the depth and length of required needle trajectory during scout scanning was inserted via in-plane technique. The needle was directed from a
Study: NCT06660940

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Keluoxin Capsules
Description: Treatment period (52 weeks):Keluoxin Capsules, 4 capsules/time, swallow with warm water after meals, 3 times/day
Study: NCT05348564

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Direct contact of family members for cascade screening of relevant variants
Description: Study team members will directly contact potentially impacted family members to offer genetic testing of relevant variant.
Study: NCT05483764

Intervention type: DEVICE
Intervention: Ultrasonographic evaluations
Description: Ultrasonographic evaluations of the talar cartilage will be performed with an 8 MHz linear probe (B-K Medical Ultrasound Scanner Class I Type B) by the same physiatrist according to the European Musculoskeletal Ultrasound Study Group (EURO-MUSCULUS).~Ultrasonographic evaluations of the Achilles tendon will be performed by the same physiatrist with an 8 MHz linear probe (B-K Medical Ultrasound Scanner Class I Type B) according to the European Musculoskeletal Ultrasound Study Group (EURO-MUSCULUS).