TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05375721

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ST36 acupoint injection
Description: ST36 is located on the lateral surface of leg, 3 cun distal to the lower border of the patella, 1 finger-breadth lateral to the anterior crest of the tibia, between the tibialis anterior muscle and the tendon of the extensor digitorum longus. (The breadth of patient's middle finger was the proportional unit of measure the cun, defined as the distance between the two medial ends of the creases of the interphalangeal joints when the patient's middle finger is flexed).

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: ST36 acupoint injection
Description: ST36 is located on the lateral surface of leg, 3 cun distal to the lower border of the patella, 1 finger-breadth lateral to the anterior crest of the tibia, between the tibialis anterior muscle and the tendon of the extensor digitorum longus. (The breadth of patient's middle finger was the proportional unit of measure the cun, defined as the distance between the two medial ends of the creases of the interphalangeal joints when the patient's middle finger is flexed).
Study: NCT05478083

Intervention type: DRUG
Group type: OTHER
Intervention: Leuprorelin
Description: Treatment consist of leuprorelin 3.75 mg once monthly for the first 3 months followed by 3-monthly injections of 11.25 mg. The direct start group will use leuprorelin for 36 months. The delayed start group will use standard of care in the first 18 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leuprorelin
Description: Treatment consist of leuprorelin 3.75 mg once monthly for the first 3 months followed by 3-monthly injections of 11.25 mg. The direct start group will use leuprorelin for 36 months. The delayed start group will use standard of care in the first 18 months.
Study: NCT05633472

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: Vitamin D (2000IU/day) for 6 months

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05185999

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Icodextrin/Dextrose
Description: Single 8 hour dwell of a 500mL intraperitoneal sodium-free 30% Icodextrin / 10% Dextrose solution
Study: NCT06113055

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: L-serine
Description: Active comparator

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo comparator
Study: NCT06409468

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subperiostal tunnel in conjunction with Novomatrix
Description: An intrasulcular incision on the tooth with recession and on each adjacent tooth. Subperiosteal pouches dissected apically for about 6-8 mm facial to the 3 teeth and connected by extension of the subperiosteal dissection into the interdental areas to create a tunnel. NovoMatrix trimmed to a vertical dimension of 7-8 mm and a horizontal length to completely over the exposed roots and extend laterally to the root line angles of the adjacent teeth. The graft inserted into the tunnel and aligned. Both the overlying tissue and graft positioned 1mm coronally to the level of the cementoenamel junction and secured with a 6-0 resorbable sling suture.
Study: NCT05943132

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mediational Intervention for Sensitizing Caregivers (MISC)
Description: MISC-CBO is a year-long semi-structured, manualized video-feedback caregiver intervention that targets key components in caregiver-child interactions known to improve caregiving quality and child outcomes. These components include emotional and cognitive components shown to improve socio-emotional and cognitive developmental outcomes in children.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Treatment as Usual
Description: Treatment as Usual includes general support for children in homework and nutrition.
Study: NCT04924517

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Extended Evening Fasting
Description: Participants will undertake 4 days of extended evening fasting (feeding between 8am-4pm). The participants will visit the laboratory on day 1, following a 16 h fast, where baseline measures will be taken and the response to a standardised meal will take place. The participant will also have an opportunity to feed ad-libitum before they leave the laboratory. The participant will continue to adhere to the feeding window on day 2 and day 3, although this will be in free-living conditions. On day 4, the participant will arrive back to the lab for post-intervention assessment, identical in format to day 1 with a metabolic assessment and energy intake assessment via a ad-libitum meal.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants will undertake 4 days of a standard western feeding pattern (feeding between 8am-8pm). The participants will visit the laboratory on day 1, following a 12 h fast, where baseline measures will be taken and the response to a standardised meal will take place. The participant will also have an opportunity to feed ad-libitum before they leave the laboratory. The participant will continue to adhere to the feeding window on day 2 and day 3, although this will be in free-living conditions. On day 4, the participant will arrive back to the lab for post-intervention assessment, identical in format to day 1 with a metabolic assessment and energy intake assessment via a ad-libitum meal.
Study: NCT02369393

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Activation
Description: Behavioral Activation intervention promotes the involvement in meaningful activities close to personal values.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Physical Activity intervention promotes the gradual increase of the frequency and intensity of PA levels, with special attention to motivational strategies.
Study: NCT05215834

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remifentanil
Description: 1. Remimazolm and Remifentanil (RR group): anesthesia was induced with remimazolam 6 mg/kg/h by continuous intravenous (IV) infusion and with the effect-site concentration of remifentanil 4 ng/ml and until the loss of consciousness (LoC), followed by remimazolam 1-2 mg/kg/h and remifentanil 3 ng/ml until the end of surgery.~2. Propofol and Remifentanil (PR group), anesthesia was induced with the effect-site concentration of propofol of 6.0 μg/ml and remifentanil 4 ng/ml, and until the loss of consciousness (LoC), followed by the effect-site concentration of propofol of 2-4 μg/ml and remifentanil 3 ng/ml until the end of surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remifentanil
Description: 1. Remimazolm and Remifentanil (RR group): anesthesia was induced with remimazolam 6 mg/kg/h by continuous intravenous (IV) infusion and with the effect-site concentration of remifentanil 4 ng/ml and until the loss of consciousness (LoC), followed by remimazolam 1-2 mg/kg/h and remifentanil 3 ng/ml until the end of surgery.~2. Propofol and Remifentanil (PR group), anesthesia was induced with the effect-site concentration of propofol of 6.0 μg/ml and remifentanil 4 ng/ml, and until the loss of consciousness (LoC), followed by the effect-site concentration of propofol of 2-4 μg/ml and remifentanil 3 ng/ml until the end of surgery.
Study: NCT05325567

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mini open incision CTR
Description: two techniques commonly used for carpal tunnel release are being compared to determine if one vs. the other provides superior patient outcomes.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mini open incision CTR
Description: two techniques commonly used for carpal tunnel release are being compared to determine if one vs. the other provides superior patient outcomes.
Study: NCT05254262

Intervention type: PROCEDURE
Intervention: Elderly surgical patients
Description: Patients who needs elective or emergency surgery for any reason
Study: NCT04526639

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality-based Interactive Cognitive Training Program
Description: Three virtual reality-based games designed to train inhibitory control, working memory, and cognitive flexibility among children with TBI

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Virtual Reality Game
Description: A virtual playground for control group to interact without training executive functions
Study: NCT06464198

Intervention type: PROCEDURE
Intervention: simultaneous postoperative radiochemotherapy
Description: The efficacy and tolerability of simultaneous postoperative radiochemotherapy is being investigated.
Study: NCT05186688

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Braining
Description: Braining is a clinical invention that helps patients in psychiatry to start and execute physical exercise (PE) regularly in psychiatric care. The core components are basic moderate to vigorous aerobic group training session and motivational work led by the psychiatric staff. Braining is used as add-on treatment to regular psychiatric care and is included in the patient care plan.
Study: NCT03994965

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pimavanserin 34 milligrams (MG) [Nuplazid]
Description: Daily treatment with 34 mg per os for 6 weeks. Followed by a wash-out period up to 14 days, do to the theoretical risk of corrected QT interval (QTc) prolongation. Conventional anti-psychotic treatment will be initiated only upon normal ECG.
Study: NCT05981482

Intervention type: DIAGNOSTIC_TEST
Intervention: OxVPS
Description: Comparing a new screening tool, the Oxford visual perception screening, to the gold standard, Rivermead Perceptual Battery Assessment.
Study: NCT05659368

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: tirzepatide once weekly
Study: NCT05936398

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Respiratory Muscle Training - VIH
Description: The VIH group will train every second day with gradual progression based on session length and breathing frequency. Participants will begin with 3 minutes of exercise with a frequency of 20 breaths·min-1 during the first session and add no more than 1 minute or 2 breaths·min-1 with each consecutive session.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Respiratory Muscle Training - ITPL
Description: The IPTL group will train 5 days a week, twice a day, with at least 6 hours break between sessions. The session will consist of 30 dynamic inspiratory maneuvers with progressive overload based on gradually increased resistance. The VIH group will train every second day with gradual progression based on session length and breathing frequency. Participants will begin with 3 minutes of exercise with a frequency of 20 breaths·min-1 during the first session and add no more than 1 minute or 2 breaths·min-1 with each consecutive session.
Study: NCT06440941

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chatbot-based mindfulness-based stress reduction
Description: During the intervention, participants will be involved in a developed chatbot and undergo a single-item assessment to verify the stability of their mental states for subsequent mindfulness-based stress reduction (MBSR) sessions, deemed stable if rated as excellent, very good, or good; They will then engage in conversations with the chatbot, responding to prompts like What is the most recent thing that made you happy? to foster interactive communication and relaxation. Subsequently, participants need to follow guided MBSR sessions and are encouraged to interact with the chatbot for at least one hour daily; all interactions will be monitored and recorded. After eight weeks, a post-intervention assessment will be conducted, followed by pre-post statistical analyses. A total of ten participants with the most and least significant changes in depression levels will be selected for an open-ended questionnaire.
Study: NCT04703764

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSG4112
Description: Once-daily, 14-day multiple oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSG4112
Description: Once-daily, 14-day multiple oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Once-daily, 14-day multiple oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Once-daily, 14-day multiple oral administration
Study: NCT05717192

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: InterVapor®-System
Description: The InterVapor System uses heated water vapor to ablate the airways and parenchyma within targeted regions of the lung. Lung remodeling occurs after an initial localized inflammatory response and a subsequent healing and repair. The remodeling of the tissue results in reductions in tissue and air volume in the targeted regions of the lung. The remodeled lung tissue does not re-inflate as a result of collateral ventilation.~The lung volume reduction of diseased hyper-inflated lung segments after InterVapor treatment is expected to increase elastic recoil by reducing the most compliant segments of the lung, decompressing segments of healthier lung allowing for alveolar recruitment, and improving the mechanical efficiency of the respiratory muscles. These mechanical changes are anticipated to improve pulmonary function, exercise capacity and quality of life.
Study: NCT04659616

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspirate
Description: Undergo bone marrow biopsy and aspirate

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy and aspiratie

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daunorubicin
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electrocardiography
Description: Undergo ECHO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemigatinib
Description: Given PO
Study: NCT05248659

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sibeprenlimab 400 mg s.c. Q4weeks
Description: Sibeprenlimab 400 mg s.c. q 4 weeks
Study: NCT05683834

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Matrix-M1 Adjuvant
Description: Matrix-M1 is composed of 2 types of 40 nm-sized particles each with a different saponin fraction (fraction A and fraction B) combined with cholesterol and phospholipid.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EBV gp350-Ferritin Vaccine
Description: The EBV gp350-Ferritin vaccine is composed of Helicobacter pylori non-heme ferritin fused to EBV gp350 which self-assembles to form a nanoparticle. The vaccine is supplied in single-use vials at a concentration of 250 micrograms/mL in 1.7 mM KH2PO4, 5 mM Na2HPO4, 150 mM NaCl, 5% sucrose, pH 7.4 (diluent).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator
Description: Normal Saline
Study: NCT04647240

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Dermacyte® Liquid (human amniotic fluid)
Description: Subcutaneous injection into and/or around wound bed weekly

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Dermacyte® Liquid (human amniotic fluid)
Description: Subcutaneous injection into and/or around wound bed weekly
Study: NCT06474494

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Application of one layer
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying one layer of Scotchbond Universal Plus adhesive

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Application of one layer
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying one layer of Scotchbond Universal Plus adhesive

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Application of double layer
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying double layer of Scotchbond Universal Plus adhesive
Study: NCT04485104

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GWP42003-P
Description: Oral Solution
Study: NCT06648213

Intervention type: OTHER
Group type: OTHER
Intervention: Physiotherapy
Description: Therapy group: In addition to routine care, they will be arranged according to the needs of the baby in the form of positioning, hand contacts, passive and active movement of the arms and legs for the development of movement, sensory stimuli around the mouth for oral motor organisation. Neurodevelopmental-based application will be applied three days a week, once a day for 10-15 minutes, from the 34th week until 36th week when vital signs are stable.
Study: NCT06230822

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VUM02 Injection
Description: VUM02 Injection will be administered intravenously every 3 days for a total of 3 doses.
Study: NCT06474494

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Application of double layer
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying double layer of Scotchbond Universal Plus adhesive

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Etch-and-rinse application mode
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying Scotchbond Universal Plus adhesive applied as etch-and-rinse application mode

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Etch-and-rinse application mode
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying Scotchbond Universal Plus adhesive applied as etch-and-rinse application mode
Study: NCT05957601

Intervention type: OTHER
Intervention: No intervention was made as it was a descriptive epidemiological study.
Description: No intervention was made as it was a descriptive epidemiological study.
Study: NCT04366895

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional single implant overdenture
Description: conventional manufactured implant overdenture
Study: NCT05746195

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dietary intervention via Text Messaging
Description: Text messages will be sent to participants cell phones using the HealthySMS platform

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Various questionnaires evaluating participants dietary habits and use of study intervention will be administered
Study: NCT05857683

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: cextension pin block
Description: this is the technique for mallet finger where 2 pins are used, one for the extension block and other intramedullary for the extension posture

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pin orthosis- extension block pin
Description: this is the technique for mallet finger where only 1 pin is used for extension block and an orthosis is applied for the extension posture
Study: NCT05746195

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition Education
Description: Participants will receive nutrition education materials
Study: NCT04191590

Intervention type: PROCEDURE
Group type: OTHER
Intervention: nasal brushing and bacteriological sample
Description: A nasal brushing as well as a bacteriological sample using a swab under general anesthesia at the beginning of the endonasal surgery procedure

Intervention type: PROCEDURE
Group type: OTHER
Intervention: nasal brushing and bacteriological sample
Description: A nasal brushing as well as a bacteriological sample using a swab under general anesthesia at the beginning of the endonasal surgery procedure
Study: NCT04366895

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3d printed single implant overdenture
Description: CAD-CAM manufactured implant overdenture.
Study: NCT06474494

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Selective enamel etching application mode
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying Scotchbond Universal Plus adhesive applied as selective enamel etching mode

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Selective enamel etching application mode
Description: 35 non-carious cervical lesions (NCCL) will receive composite resin restorations applying Scotchbond Universal Plus adhesive applied as selective enamel etching mode
Study: NCT05457504

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remote blood pressure monitoring
Description: Participants assigned to this arm will participate in the experimental intervention

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: Participants assigned to this arm will participate in a placebo intervention
Study: NCT04913558

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: The exercise will be performed by using the treadmill as the following:~- The first stage (warming up): It consists of 5 minutes warming up with the treadmill speed set at 1.0 mile per hour.~- The second stage (active stage): It consists of 20 minutes with the treadmill speed set at 3.0 miles per hour.~- Third stage (cooling down): It consists of 5 minutes of cooling down with the treadmill speed set at 1.0 miles per hour.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Treatment
Description: 1. General advice for reducing fatigue and stress~2. Fluid and diet advice~3. Carrying the Baby~4. While Breastfeeding in a sitting position~5. Selecting Clothing

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Treatment
Description: 1. General advice for reducing fatigue and stress~2. Fluid and diet advice~3. Carrying the Baby~4. While Breastfeeding in a sitting position~5. Selecting Clothing
Study: NCT05383183

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Choline Alfoscerate 400mg
Description: Oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral administration
Study: NCT05850611

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylene Blue
Description: The first intervention group includes diabetic patients with chronic foot ulcers who, despite common treatments, will be undergone oral methylene blue intervention for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk (control)
Description: Group B will receive 200 ml of milk for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
Description: Group C will be undergone synergistic 4-week treatment with oral methylene blue and fibrin glue.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Milk and Platelet-Rich Plasma-Fibrin Glue (control)
Description: Group D will be treated only with fibrin glue and 200 ml of milk for 4 weeks.