TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06660108

Intervention type: GENETIC
Group type: OTHER
Intervention: blood draw
Description: Multiple blood draw for genomic and transcriptomic investigations
Study: NCT06659510

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: education
Description: ACCORDING TO THE RESULTS AFTER THE SURVEY APPLICATION, TRAINING WAS PROVIDED TO THE ADDICTIVE STUDENTS IN THE EXPERIMENT GROUP AND MESSAGES WERE SENT FROM WHATSAPP APPLICATION IN THE FOLLOWING 2 MONTHS AFTER THE TRAINING.
Study: NCT06661057

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vivally system stimulation
Description: During the first month, participants will do the stimulation at different time points: 1) supine while in bed, 2) seated in the morning, 3) sitting in the afternoon, and 4) sitting in the evening. Participants will measure the circumference of their ankle prior to each use. Participants will use the System for an additional 2 months with the preferred stimulation parameters based on the study team's recommendations from the first month of use.
Study: NCT06658834

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone Combined with romiplostim N01
Description: Dexamethasone (HD-DXM) at a dose of 40mg/d for 4 days constitutes one cycle. If there is no response on the 10th day, repeat it once. The administration can be either oral or intravenous. Meanwhile, romiplostim N01 is administered with an initial dose of 3µg/kg by subcutaneous injection once a week for up to 6 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone monotherapy
Description: Dexamethasone (HD-DXM) 40mg/d × 4 days, one cycle. If there is no response on the 10th day, repeat once, administered either orally or intravenously.
Study: NCT06660186

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rigid Sternal Fixation
Description: The surgeon will close the sternum (breastbone) using the SternalPlate system. The SternalPlate System consists of implants and instruments used to hold the two halves of the sternum together.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Wire Cerclage
Description: The surgeon will close the sternum (breastbone) using Wire Cerclage. Wire Cerclage consists of stainless steel wires used to hold the two halves of your sternum together.
Study: NCT06659406

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Coenzyme Q10
Description: Coenzyme Q10 will be given once daily, 200mg for the period of 3 months
Study: NCT06662175

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyperbaric bupivacaine
Description: Group A (Unexposed) will received 2 ml of intrathecal bupivacaine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hyperbaric bupivacaine and dexmedetomidine
Description: Group B (Exposed) will receive a combination of bupivacaine and Dexmedetomidine infusion
Study: NCT06659497

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: web-based patient education
Description: The web-based training, which will provide the following information about the IUI treatment process, will last a total of 60 minutes.~MODULE 1: General Information About Fertility MODULE 2: Diagnostic and Therapeutic Methods in Infertility / Insemination Treatment MODULE 3: Drugs Used in Insemination Treatment and Their Application MODULE 4: Things to Consider After Insemination
Study: NCT06600282

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Parecoxib
Description: Pharmacokinetic study under fasting conditions

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Parecoxib
Description: Pharmacokinetic study under fasting conditions
Study: NCT06661629

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nerve stimulation
Description: The intervention is testing the effect of bilateral genioglossus muscle stimulation on upper airway collapsibility during drug-induced sleep endoscopy in patients implanted with the Inspire hypoglossal nerve stimulator
Study: NCT06658626

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [¹⁴C]Enlicitide chloride
Description: IV Injection
Study: NCT06661785

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: large orbital floor fracture
Description: Twenty two patients with large orbital floor fracture will be reconstructed with interlocking polyetheretherketone patient-specific implant
Study: NCT06660992

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK31858, tablet
Description: HSK31858 is a novel inhibitor of DPP1 developed by Hisco Pharmaceutical and can reduce pulmonary exacerbations over a 52-week treatment period in patients with non-cystic fibrosis bronchiectasis

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: the placebo comparator of study
Study: NCT06662006

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nal-IRI,5-fu,LV, benmelstobart, anlotinib
Description: liposomal irinotecan (nal-IRI) plus 5-fluorouracil (5-FU)/leucovorin (LV) (nal-IRI/5-FU/LV) combined with benmelstobart and anlotinib ± SBRT
Study: NCT06658093

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rapamycin
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rapamycin
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rapamycin
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rapamycin
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: mTOR inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: mTOR inhibitor
Study: NCT05435859

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Speech Tasks
Description: Listen to 25-minutes of speech sounds in English.
Study: NCT06658093

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inert placebo for rapamycin or everolimus
Study: NCT06659692

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gonadotropins Subcutaneous
Description: Gonadotropins s.c. multiple dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gonadotropins Subcutaneous
Description: Gonadotropins s.c. multiple dose
Study: NCT05034627

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calaspargase Pegol-mknl
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cobimetinib
Description: Given PO
Study: NCT06625606

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine 0.5% Injectable Solution
Description: The patient's back was prepared for surgery. They were positioned on their side, with the operative side facing upward. The L3-4 spinal interspace was identified, and numbed, and a thin spinal needle was inserted. After confirming Cerebrospinal Fluid (CSF), 12.5 mg of isobaric bupivacaine 0.5% was injected into the spinal canal.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine 0.5% Injectable Solution
Description: The L3-4 spinal interspace was identified, numbed, and a thicker needle (Tuohy needle) was inserted. After confirming Cerebrospinal Fluid (CSF), a thin catheter was inserted into the spinal canal and secured. An initial dose of 1 ml isobaric bupivacaine 0.5% was injected, followed by additional doses as needed to maintain the block height.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isoflurane Inhalant Product
Description: General anesthesia was initiated with propofol and rocuronium. Anesthesia was maintained with isoflurane, with additional rocuronium and fentanyl as needed. Breathing was controlled by the ventilator, and muscle relaxation was reversed at the end of surgery.
Study: NCT06625138

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Latex Band
Description: Hemorrhoid banding with latex band

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-Latex Band
Description: Hemorrhoid banding with non-latex bands
Study: NCT04720755

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-Intensity Extracorporeal Shock Wave Therapy
Description: Twice-weekly treatments for 6 weeks, of 0.2mL/mm\^2 administered for 500 shocks per treatment site, for a total of 3000 shocks per week.
Study: NCT06292637

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Faith Fellowship to Improve Thy Health (CB-FAITH)
Description: CB-FAITH is a behavioral depression intervention set inside a cognitive behavioral framework, and Afrocentric paradigm and informed by faith-based principles, designed to treat major depressive disorder among African American adults. The 13-treatment modules focus on increasing knowledge of depression and healthy coping behaviors. It is designed to be co-delivered by licensed mental health clinicians and pastors at churches.
Study: NCT06459999

Intervention type: DIAGNOSTIC_TEST
Intervention: Urine and circulating blood biomarkers
Description: Urine and circulating blood biomarkers in all cohorts

Intervention type: DIAGNOSTIC_TEST
Intervention: Urine and circulating blood biomarkers
Description: Urine and circulating blood biomarkers in all cohorts

Intervention type: DIAGNOSTIC_TEST
Intervention: Urine and circulating blood biomarkers
Description: Urine and circulating blood biomarkers in all cohorts
Study: NCT06180629

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music conset
Description: The music modes to be used (Rast and Hüseyni), classical music, nature music, and listening time of 20-30 minutes were determined by taking expert opinion from a faculty member from the Conservatory department and by reviewing the literature. The researcher asked the patients to choose the music genres. After each patient decided on the music they wanted to listen to, the researcher recorded the selected music genres on their smartphones. The music playback application was played to the patients in the experimental group for 20-25 minutes in each session for 4 sessions, i.e. 4 times in total, once a week for a month, until the end of one course. During each session, the patients listened to the music genre they had chosen each week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: normal treatment routine
Description: normal treatment routine
Study: NCT05969639

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HEYA
Description: The HEYA program is a 12-week app-delivered psychoeducational program that comprises of nutrition education, skills training on self-regulation, and weekly feedback.
Study: NCT06034873

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol injection and fentanyl
Description: The sequence will be to inject fentanyl 1 μg•kg-1•min-1 first within 1 min and then inject propofol 2 mg•kg-1•min-1.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: Patients will be anesthetized with ultrasound-guided pericapsular nerve group block (PENG block) using 20 ml of 0.25% bupivacaine.
Study: NCT05035953

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Edaravone Dexborneol matching injection, addition to thrombolysis
Study: NCT05953597

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition Education
Description: The intervention will consist of 12 monthly nutrition education sessions catered to people with spinal cord injuries. The curriculum is based on the 2020-2025 Dietary Guidelines for Americans such as consuming recommended amounts of fruits/vegetables, whole grains, etc. The sessions will be approximately 30-60 minutes and will be available in-person.
Study: NCT04742803

Intervention type: DEVICE
Group type: OTHER
Intervention: Straberi Epistamp Microneedling Treatment
Description: The patient's entire face will be treated with the Straberi Epistamp needling device.~The following settings will be used as a treatment protocol. Needle length between .02- 1.55 mm

Intervention type: DEVICE
Group type: OTHER
Intervention: Straberi Epistamp Microneedling Treatment
Description: The patient's entire face will be treated with the Straberi Epistamp needling device.~The following settings will be used as a treatment protocol. Needle length between .02- 1.55 mm
Study: NCT04927156

Intervention type: DEVICE
Intervention: BALT medical devices
Description: Includes, but is not limited to, the following:~* Access devices~* Aneurysm treatment devices~* Ischemic Stroke and peripheral occlusive diseases treatment devices~* Arterio-Venous Malformations/fistulas treatment devices
Study: NCT04943341

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Eco-guided Triamcinolone-Acetonide injection
Description: The treatment consists in injecting 1 ml of Kenacort (corresponding to 40 mg of Triamcinolone Acetonide) diluted in about 1 ml of local anesthetic (Lidocaine) directly into the medial fold of the knee. Through an ultrasound guidance with in plane technique, the flute beak of the needle will be positioned between the two sheets of the synovial fold and the injection will be performed.
Study: NCT05446766

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-guided Exposure-based Digital Intervention for Health Anxiety
Description: An 8-week self-guided internet based CBT intervention which consists of text, exercises, examples and automated support. The format, potentially more accessible compared to traditional ICBT, will be developed with the aim to enhance treatment comprehension and motivation in the participants. The program consists of eight modules (chapters) where the main therapeutic focus is exposure with response prevention.~Participant will be interviewed before the program starts, after 8 weeks and 3 months after the program ends. If in need for technical support, participant will be able to ask for assistance via the program and will then be contacted by a clinician via telephone within a couple of days.
Study: NCT06106061

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Decompression + FFX®
Description: Surgical treatment of degenerative lumbar spinal stenosis by spinal decompression associated with the use of FFX® implant

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Decompression alone
Description: Surgical treatment of degenerative lumbar spinal stenosis by spinal decompression alone
Study: NCT06520462

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pharmacopuncture
Description: The physicians will decide the specific methods of pharmacopuncture based on the clinical judgment according to each participant's conditions. All applied treatment methods are documented in the case report forms.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture
Description: The physicians will decide the specific methods of acupuncture based on the clinical judgment according to each participant's conditions. All applied treatment methods are documented in the case report forms.
Study: NCT04566900

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neurofeedback
Description: Neurofeedback is a technique where brain functions are made accessible to the subject in the form of a metaphor. For instance, frontal brain activity may be shown as an airplane flying. Once the activity is made accessible, the subject can modulate it in a pre-specified direction. The parameters used to achieve successful feedback are made difficult over time and hence the brain is taught or conditioned to improve performance.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Placebo
Description: Subjects in this arm will undergo all of the same testing as active treatment. Music and video progression will not depend on brain activity. Instead feedback will be random.
Study: NCT06035172

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: guided imagery
Description: The guided imagery technique, which is one of these methods, is used in the method of pain by establishing a connection between mind and body. In the technique, a peaceful scene is depicted in which positive energy is reflected in the person to ensure complete relaxation and relaxation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: music recital
Description: It is stated that the acemasiran tune (instrumental music) has a reducing effect on the duration of labor, as well as having labor pain and muscle relaxant properties.
Study: NCT05898620

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NGN-401
Description: NGN-401 is a non-replicating, recombinant AAV9 carrying a full length human MECP2 transgene.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NGN-401
Description: NGN-401 is a non-replicating, recombinant AAV9 carrying a full length human MECP2 transgene.
Study: NCT05056805

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercise
Description: Receive aerobic exercise encouragement

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise
Description: Receive aerobic exercise encouragement

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary Intervention
Description: Consume high protein snack/meal/shake

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Nutritional Intervention
Description: Receive nutritional consultation and guidelines

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutritional Intervention
Description: Receive nutritional consultation and guidelines

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Training
Description: Complete strengthening exercise
Study: NCT05749224

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Helkimo Index
Description: Helkimo Index is comprised of five items, with each assessment having three possible answers, scored as 0, 1 or 5. The first item is related to the limitation in the range of jaw movement. The second item evaluates the alterations of joint function that produce deviations, sounds and/or joint locks or blockages; the third item evaluates the presence of pain when performing some movements; the fourth item evaluates muscular pain in the masticatory muscles; and the fifth item evaluates the presence of discomfort or pain in the prearticular area of the temporomandibular joint (TMJ) through palpation. From the sum of the 5 items, we identify no TMJ involvement if the score is 0, mild TMJ involvement when the score ranges from 1 to 9, moderate TMJ involvement if the score ranges between 10 and 19 and severe TMJ involvement for a score between 20 and 25.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Helkimo Index
Description: Helkimo Index is comprised of five items, with each assessment having three possible answers, scored as 0, 1 or 5. The first item is related to the limitation in the range of jaw movement. The second item evaluates the alterations of joint function that produce deviations, sounds and/or joint locks or blockages; the third item evaluates the presence of pain when performing some movements; the fourth item evaluates muscular pain in the masticatory muscles; and the fifth item evaluates the presence of discomfort or pain in the prearticular area of the temporomandibular joint (TMJ) through palpation. From the sum of the 5 items, we identify no TMJ involvement if the score is 0, mild TMJ involvement when the score ranges from 1 to 9, moderate TMJ involvement if the score ranges between 10 and 19 and severe TMJ involvement for a score between 20 and 25.
Study: NCT06642246

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: During a 7-week intervention phase, parent-child dyads will be provided a sleep duration goal paired with a loss-framed financial incentive (virtual account) starting with deductions each time the sleep goal is not met, will be sent sleep guidance text messages, and will receive weekly performance feedback text messages.
Study: NCT05372653

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OPA-15406
Description: 0.3% or 1% ointment, topical, twice daily, for 52 weeks
Study: NCT05036018

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ACURATE neo2
Description: The ACURATE neo2 valve will be implanted using a two-step mechanism during transfemoral transcatheter aortic valve implantation (TAVI). Balloon predilatation will be recommended in the ACURATE neo 2 valve group.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ACURATE neo2
Description: The ACURATE neo2 valve will be implanted using a two-step mechanism during transfemoral transcatheter aortic valve implantation (TAVI). Balloon predilatation will be recommended in the ACURATE neo 2 valve group.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: minimalist approach
Description: Isolated local anesthesia. Central venous lines, additional arterial lines for blood pressure monitoring, and urinary catheters will be avoided. Insertion of temporary pacemakers is optional and should be avoided whenever possible, and peri-procedural pacing can then be performed on the left ventricular wire. Presence of an anesthesiologist is optional. Patients will be directly transferred to the cardiology ward after the procedure, which can be postponed in case of complications.
Study: NCT05667545

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Peptide
Description: it is about synthetic protein acting on tooth structure help information apatite crystals

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Peptide
Description: it is about synthetic protein acting on tooth structure help information apatite crystals
Study: NCT06501638

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Memantine Hydrochloride 10 MG
Description: Take Memantine Hydrochloride for intervention First week, 5mg(half the tablet), p.o.，bid. Second to Sixth week, 10mg(one tablet), p.o., bid
Study: NCT04646304

Intervention type: OTHER
Group type: OTHER
Intervention: Objective Feedback (Motion Capture)
Description: Participants assigned to the objective feedback group will be given a report after completing Set 1 and Set 2. This report will outline their performance for each significant factor (identified in Phase 1) relative to a target interval, derived from the staff surgeon group average (± one standard deviation). Participants assigned to the objective feedback group will then be able to repeat the tasks knowing which variables to improve.
Study: NCT05875727

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 20-valent pneumococcal conjugate vaccine
Description: One dose of 20vPnC will be administered intramuscularly.