TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06547177

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit juice
Description: During labor, one group will follow the routine while the water group will only take water and fruit juice group will take water and fruit juice.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit juice
Description: During labor, one group will follow the routine while the water group will only take water and fruit juice group will take water and fruit juice.
Study: NCT05945290

Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo blood and leftover tissue sample collection

Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Medical records are reviewed
Study: NCT05331508

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: gender-based violence screening, first-line support (LIVES) and reproductive coercion empowerment counseling (ARCHES)
Description: Providers will (1) introduce routine client screening for GBV, including intimate partner violence, sexual violence, and reproductive coercion using a standardized screening form, in FP and ANC services,(2) for individuals disclosing GBV, provide first-line response-empathetic counseling, including listening, inquiring about experiences sensitively, and validating experiences, helping clients develop safety plans, and providing support; (3) regardless of disclosure of GBV, provide counseling and information, education and communication (IEC) materials on IPV, including reproductive coercion, and FP options, to both FP and ANC clients.
Study: NCT05567172

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Left atrial appendage closure device WM FLX Pro
Description: Left atrial appendage closure
Study: NCT05393232

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dietitian-Assisted DASH groceries
Description: The DASH (Dietary Approaches to Stop Hypertension), is a healthy dietary pattern that lowers blood pressure without reducing weight. The DASH diet emphasizes fruits, vegetables, and low-fat dairy products; includes whole grains, poultry, fish, and nuts; and is reduced in red meat, sweets, and sugar-containing beverages.~Intervention Phase:~This intervention is a weekly, 12-week DASH dietary intervention. A dietitian will assist participants in ordering groceries in a pattern consistent with the DASH diet to be delivered to their homes. The quantity of groceries will be based on participant Calorie needs and family size.~Observation Phase:~For months 4-12 of the study, participants will be asked to continue following a DASH grocery shopping pattern without the provision of weekly groceries.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-directed shopping
Description: Intervention Phase:~Participants will receive some basic information on healthy eating and a monthly stipend at 4, 8, and 12-weeks of the intervention.~Observation Phase:~For months 4-12 of the study, participants will be asked to follow their typical shopping pattern without the provision of a monthly stipend.
Study: NCT04763330

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care (EUC)
Description: Enhanced Usual Care (EUC) consists of Collaborative Safety Planning, a VA usual care practice. It is a tool that Veterans can use when they are in an acute suicidal crisis. The condition is considered enhanced because Veterans in this condition receive 6 sessions total, Safety Planning which is delivered in 1-2 sessions and 4-5 sessions of check-ins with a brief assessment. Safety Planning involves a worksheet completed by the patient in collaboration with a health provider.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Solving Therapy (PST) plus EUC
Description: Veterans randomized to this condition received EUC and PST. EUC is delivered in both conditions to ensure the safety of all Veterans enrolled in the study. In addition to EUC, Veterans in this condition receive PST, which teaches patients a structured planful problem solving approach to: 1) identify problems and set goals, 2) generate alternative solutions, 3) select a solution based on cost-benefit analysis, and 4) devise and implement a plan for the solution and assess its effectiveness in solving the problem. This contemporary PST protocol also teaches tool kits to address obstacles highly pertinent to the challenges faced by older Veterans with mental health disorders and active suicidal ideation: emotion dysregulation, hopelessness, and feeling overwhelmed by too much information (brain overload) or stress.
Study: NCT06644118

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OL-101 infusion
Description: OL-101 infusion will be administered to patients via IV infusion at the assigned dose.
Study: NCT04987411

Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of methane concentrations in exhaled breath
Description: To measure methane concentrations, a near-infrared laser technique-based photoacoustic apparatus will be attached to the exhalation outlet of the ventilator upon arrival of severely injured patients. Exhaled methane levels will be monitored continuously during the first 72 in-hospital hours and will be recorded at pre-determined time points (directly upon arrival, 6 hours post-admission, 12 hours post-admission, 24 hours post-admission, 48 hours post-admission and 72 hours post-admission).

Intervention type: DIAGNOSTIC_TEST
Intervention: Videomicroscopy of the sublingual microcirculation
Description: Orthogonal polarization spectral imaging technique (Cytoscan A/R, Cytometrics) will be used to visualize the microcirculation of the sublingual mucosa of the patients. The OPS technique utilizes reflected, polarized light at the wavelength of the isobestic point of oxyhemoglobin and deoxyhemoglobin (548 nm). The diminution of sublingual microcirculation can refer to circulatory redistribution due to hemorrhage. Sublingual microcirculation of the patients will be visualized and evaluated at pre-determined time points (directly upon arrival, 6 hours post-admission, 12 hours post-admission, 24 hours post-admission, 48 hours post-admission and 72 hours post-admission) during the first 72 in-hospital hours.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood gas and laboratory analysis
Description: Arterial blood gas analysis and laboratory testing of venous blood are routine examinations in clinical practice. Base deficit and lactate are considered as global markers of blood loss and shock, and can be obtained rapidly with blood gas analysis. Hemoglobin and hematocrit values can correspond to the severity of blood loss, and are measured routinely both from arterial and venous blood. Sampling of arterial and venous blood for blood gas and laboratory analyses will be performed at pre-determined time points (directly upon arrival, 24 hours post-admission, 48 hours post-admission and 72 hours post-admission) during the first 72 in-hospital hours.

Intervention type: DIAGNOSTIC_TEST
Intervention: Hemodynamic monitoring
Description: Hemodynamic monitoring is an essential part of emergency trauma care. Non-invasive monitoring of blood pressure, heart rate and respiratory rate of patients will be started immediately upon arrival. After patients are stabilized, invasive arterial blood pressure (IABP) monitoring can be started. IABP is considered as the gold standard of blood pressure measurement in critical care as it reflects the fluctuations of blood pressure in real time. Blood pressure and heart rate values will be recorded at pre-determined time points (directly upon arrival, 6 hours post-admission, 12 hours post-admission, 24 hours post-admission, 48 hours post-admission and 72 hours post-admission) during the first 72 in-hospital hours.
Study: NCT06373185

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided sacral erector spinae plane block
Description: Patients were received ultrasound-guided sacral erector spinae plane block, 1ml/kg %0.25 bupivacaine (max 20 ml), for postoperative pain management

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided caudal block
Description: Patients were received ultrasound-guided caudal block, 1ml/kg %0.25 bupivacaine (max 20 ml), for postoperative pain management
Study: NCT05472350

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Breztri Aerosphere
Description: Breztri Aerosphere is used to control and prevent symptoms (such as wheezing and shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD, which includes chronic bronchitis and emphysema).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo is 0.9% normal saline
Study: NCT05301881

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Surgery
Description: resection of the oligometastatic lesion(s)

Intervention type: RADIATION
Group type: OTHER
Intervention: Radiotherapy
Description: radiation of the oligometastatic lesion(s)

Intervention type: OTHER
Group type: OTHER
Intervention: Radiofrequent ablation
Description: radiofrequent ablation of the oligometastatic lesion(s)
Study: NCT05765708

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imagery
Description: Motor imagery is the mental execution of a movement without any overt movement or without any peripheral (muscle) activation. It has been shown that motor imagery leads to the activation of the same brain areas as an actual movement. Therefore, it is used to acquire new motor skills. Action Observation (AO) involves the dynamic process of observing purposeful actions with the intention of imitating and then practicing those actions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imagery
Description: Motor imagery is the mental execution of a movement without any overt movement or without any peripheral (muscle) activation. It has been shown that motor imagery leads to the activation of the same brain areas as an actual movement. Therefore, it is used to acquire new motor skills. Action Observation (AO) involves the dynamic process of observing purposeful actions with the intention of imitating and then practicing those actions.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Action Observation
Description: Action Observation (AO) involves the dynamic process of observing purposeful actions with the intention of imitating and then practicing those actions.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Action Observation
Description: Action Observation (AO) involves the dynamic process of observing purposeful actions with the intention of imitating and then practicing those actions.
Study: NCT05388266

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mask ventilation
Description: Mask ventilation is performed under paratracheal pressure or no pressure in a randomized, crossover manner.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mask ventilation
Description: Mask ventilation is performed under paratracheal pressure or no pressure in a randomized, crossover manner.
Study: NCT05820360

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CoMBI-SMI
Description: The first step is analysis of the behavioral problem because the core need is insufficiently compensated by the current environment or counteracted by the behavior of people within that environment. Step 2 is to choose the right core need based on this analysis. CoMBI-SMI describes the patient's self-image, the image of others, the triggering events and the problematic behavior of the patient based on personality disorders as classified by the Diagnostical and Statistical Manual of Mental Disorders. Step 3 is to choose the nursing intervention that is easily deployable so that Healthcare providers can identify the underlying core need and reduce the behavioral problems and burden on the healthcare providers. The fourth and final step is to draw up a CoMBI plan. The CoMBI-SMI is a cyclical process where it is important that the entire team is aligned with the patient's behavioral approach. Interventions are carried out by the entire team and evaluated after an agreed period of time.
Study: NCT04884243

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CBT-006
Description: ophthalmic solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBT-006
Description: ophthalmic solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBT-006
Description: ophthalmic solution
Study: NCT06178640

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Simvastatin 40 mg film-coated tablet
Description: Simvastatin 40 mg film-coated tablet

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Simvastatin 40 mg film-coated tablet
Description: Simvastatin 40 mg film-coated tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zocor 40 mg film-coated tablet
Description: Zocor 40 mg film-coated tablet (Simvastatin 40 mg film-coated tablet: Reference Product)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zocor 40 mg film-coated tablet
Description: Zocor 40 mg film-coated tablet (Simvastatin 40 mg film-coated tablet: Reference Product)
Study: NCT05714371

Intervention type: DRUG
Intervention: Nivolumab
Description: Patients receiving nivolumab

Intervention type: DRUG
Intervention: Ipilimumab + nivolumab
Description: Patients receiving ipilimumab + nivolumab
Study: NCT04841096

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: A1=Glimepiride / Vildagliptin / Metformin (1 mg/ 50 mg/ 500 mg)
Description: Take one tablet of the prescribed dose of the investigational drug by mouth, preferably with food and in the morning. Initial dose for the first 45 days of intervention.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: B2=Glimepiride / Vildagliptin / Metformin (1 mg/ 50 mg/ 500 mg)
Description: take one tablet of the prescribed dose of the investigational drug by mouth, preferably with food and in the morning. Initial dose for the first 45 days of intervention.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: (A2) Glimepiride/Vildagliptin/Metformin
Description: Take one tablet of the prescribed dose of the investigational drug by mouth, preferably with food and in the morning. Escalation dose in cause the patient meets established criteria.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: (B2) Glimepiride/Vildagliptin/Metformin
Description: Take one tablet of the prescribed dose of the investigational drug by mouth, preferably with food and in the morning. Escalation dose in cause the patient meets established criteria.
Study: NCT04274374

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gluten-Free Diet
Description: Dietary supplement without gluten

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Gluten Diet
Description: Dietary supplement with gluten
Study: NCT06626997

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Kombucha tea
Description: During Visit 1 (week 0), a fasting blood test must be performed at the IMDEA Alimentación facilities to obtain different markers: blood lipids, blood glucose, etc. Approximately 20 mL will be extracted (for comparison, keep in mind that a donation requires 450 mL). The blood sample will be extracted by qualified nursing staff from the UNILABS Laboratory. The blood tests based on the security and privacy requirements for handling samples will be carried out by the same laboratory.~You will also be asked to provide the stool sample that you must have collected at home prior to attending that visit with the material provided at the screening visit (V0) and at the intermediate visit (V2).

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Kombucha tea
Description: During Visit 1 (week 0), a fasting blood test must be performed at the IMDEA Alimentación facilities to obtain different markers: blood lipids, blood glucose, etc. Approximately 20 mL will be extracted (for comparison, keep in mind that a donation requires 450 mL). The blood sample will be extracted by qualified nursing staff from the UNILABS Laboratory. The blood tests based on the security and privacy requirements for handling samples will be carried out by the same laboratory.~You will also be asked to provide the stool sample that you must have collected at home prior to attending that visit with the material provided at the screening visit (V0) and at the intermediate visit (V2).
Study: NCT05714371

Intervention type: DRUG
Intervention: Pembrolizumab
Description: Patients receiving pembrolizumab

Intervention type: DRUG
Intervention: Dabrafenib + trametinib
Description: Dabrafenib + trametinib
Study: NCT05255601

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Relatlimab
Description: Specified Dose on Specified Days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified Dose on Specified Days
Study: NCT05336643

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radiofluorescence
Description: Assessment of pelvic sidewall with Firefly and Sensei
Study: NCT05505747

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fisetin
Description: Fisetin is a plant flavanol senolytic found in strawberries, persimmons, and cucumbers. This naturally derived senolytic has few side effects and previous animal models of both osteoarthritis and rheumatoid arthritis have demonstrated that the senolytic supplement fisetin reduces inflammation and slows cartilage breakdown.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral capsule
Description: The oral placebo will consist of corn starch and gelatin capsules
Study: NCT05870332

Intervention type: DEVICE
Intervention: GI Genius (GIG)
Description: GIG is an artificial intelligence unit that assists human colonoscopist in real-time to detect polyps during colonoscopy.~Four months collection period prior to activating GIG, then four months with GIG, and Four months afterwards without GIG
Study: NCT05434364

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facilitated Tucking
Description: giving facilitated tucking before (1st and 3th minutes), during and after (1st and 3th minutes) the procedure

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swaddling
Description: swaddling before (1st and 3th minutes), during and after (1st and 3th minutes) the procedure

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prone Position
Description: giving prone position before (1st and 3th minutes), during and after (1st and 3th minutes) the procedure
Study: NCT05329311

Intervention type: PROCEDURE
Intervention: ERATS protocol applied
Description: Inflammatory parameters (such as; C-reactive protein (CRP), white blood cell count, neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR), lymphocyte/monocytes ratio (LMR) of the operated patients by applying the ERATS protocol will be investigated.

Intervention type: PROCEDURE
Intervention: ERATS protocol not applied
Description: Inflammatory parameters (such as; C-reactive protein (CRP), white blood cell count, neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR), lymphocyte/monocytes ratio (LMR) of the operated patients by applying without the ERATS protocol will be investigated.
Study: NCT05204368

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination of Imipenem/Cilastatin and XNW4107
Description: Imipenem/Cilastatin 500mg/500mg and XNW4107 250mg for injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Meropenem
Description: Meropenem 1g for injection
Study: NCT06406257

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3M™ Bair Hugger™ Warming Unit
Description: Utilizing the 3M Temperature Management Unit to ensure intraoperative body temperature of elderly hip surgery patients remains consistent with their preoperative baseline, while patients in Group C receive no intervention.
Study: NCT06694259

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pneumatic retinopexy with transscleral cryopexy
Description: Pneumatic retinopexy with transscleral cryopexy is a procedure used to treat certain types of rhegmatogenous retinal detachments.~Procedure steps:~Transscleral cryopexy: in this first step, the surgeon uses a cryoprobe applied to the sclera directly over the retinal tear. The cryoprobe emits extreme cold, creating a small, localized freeze that reaches the retina and seals the tear by causing a controlled scar to form. This scar tissue holds the retina in place and prevents further fluid from passing through the tear.~Gas bubble injection: after the cryopexy, a small gas bubble (usually sulfur hexafluoride (SF6) or perfluoropropane (C3F8)) is injected into the vitreous cavity. This bubble applies upward pressure on the retina, gently pressing it against the back wall of the eye, which aids in reattaching the retina.~Head positioning: for several days following the procedure, the patient must keep their head in a specific position so the gas bubble remains aligned with the retinal tear.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pneumatic retinopexy with laser photocoagulation
Description: Pneumatic retinopexy with laser photocoagulation is a minimally invasive procedure used to repair certain types of rhegmatogenous retinal detachments.~Procedure steps:~Gas bubble injection: a small gas bubble, usually sulfur hexafluoride (SF6) or perfluoropropane (C3F8), is injected into the vitreous cavity which rises and applies pressure to the detached retina, pressing it back against the eye wall and helping to reapproximate the retinal layers.~Laser photocoagulation: once the retina is positioned correctly, laser is used to create small burns around the retinal tear. This laser application causes a mild inflammatory response, creating a scar around the tear and effectively welding the retina to the underlying tissue. This seal prevents fluid from reaccumulating beneath the retina.~Head positioning: following the procedure, the patient must keep their head in a specific position for several days. This positioning ensures that the gas bubble stays aligned with the retinal tear.
Study: NCT06441058

Intervention type: OTHER
Intervention: No patient treatment is associated with the study
Description: No patient treatment is associated with the study.
Study: NCT04181281

Intervention type: DIAGNOSTIC_TEST
Intervention: Contrast enhanced ultrasound
Description: This is a regular ultrasound scanner used with an ultrasound contrast agent injected through veins to allow for kidney perfusion acquisition.

Intervention type: DIAGNOSTIC_TEST
Intervention: Contrast enhanced ultrasound
Description: This is a regular ultrasound scanner used with an ultrasound contrast agent injected through veins to allow for kidney perfusion acquisition.

Intervention type: DIAGNOSTIC_TEST
Intervention: Arterial Spin Labelling -Magnetic Resonance Imaging
Description: Arterial spin labelling is an MRI technique allow for measuring tissue perfusion. It uses magnetically labelled arterial blood water protons as a tracer.

Intervention type: DIAGNOSTIC_TEST
Intervention: Arterial Spin Labelling -Magnetic Resonance Imaging
Description: Arterial spin labelling is an MRI technique allow for measuring tissue perfusion. It uses magnetically labelled arterial blood water protons as a tracer.
Study: NCT05394077

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Active Release Technique
Description: Using Active Release Technique

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Abdominal Drawing-Maneuver
Description: Using Abdominal Drawing-Maneuver Technique