TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06615830

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard chemotherapy
Description: Each patient will receive the standard first-line chemotherapy (chosen among Gemcitabine-Abraxane, or Abraxane-Gemcitabine-FOLFOX or FOLFIRINOX, based on the clinical judgement of the treating oncologist) until disease progression.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Organoid-guided treatment
Description: Upon disease progression confirmed radiologically, the patients will receive second-line chemotherapy. Second-line chemotherapy will be selected among the most promising effective drug (or drug regimens) as predicted in vitro by their benchmarking on patient-derived organoids.
Study: NCT06617624

Intervention type: OTHER
Intervention: MRI
Description: Healthy volunteer will have a non-injected cardiovascular MRI

Intervention type: OTHER
Intervention: MRI Contrast
Description: Patients will have the gadolinium injected cardiovascular MRI

Intervention type: OTHER
Intervention: MRI Contrast
Description: Patients will have the gadolinium injected cardiovascular MRI

Intervention type: OTHER
Intervention: MRI Contrast
Description: Patients will have the gadolinium injected cardiovascular MRI
Study: NCT06676293

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Anti-PD1
Description: Pembrolizumab 100mg in normal saline 100ml infusion over 30 minutes for every two month

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD1
Description: Pembrolizumab 100mg in normal saline 100ml infusion over 30 minutes for every two month

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: asparaginase
Description: The patients will receive asparaginase 10000IU/vail IM QD for three or five days.
Study: NCT06615934

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic and resistance exercise
Description: From the first day of transplantation in the ICU until 10 days after transfer to the ward or discharge from the hospital, if needed, the patients of the group will undergo respiratory physiotherapy once a day. The process of this program includes patient assessment, clinical decision-making, and implementation of therapeutic interventions.~The interventions of the therapeutic exercise group are divided into three phases:~1. From the time the patient enters the ICU until the time of extubation;~2. From the time of extubation to the time of transfer to the ward;~3. Duration of the patient's stay in the ward.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic and resistance exercise
Description: From the first day of transplantation in the ICU until 10 days after transfer to the ward or discharge from the hospital, if needed, the patients of the group will undergo respiratory physiotherapy once a day. The process of this program includes patient assessment, clinical decision-making, and implementation of therapeutic interventions.~The interventions of the therapeutic exercise group are divided into three phases:~1. From the time the patient enters the ICU until the time of extubation;~2. From the time of extubation to the time of transfer to the ward;~3. Duration of the patient's stay in the ward.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Respiratory physiotherapy
Description: The participants of this group will receive respiratory physiotherapy daily after transplant until discharge.
Study: NCT06617637

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Based Virtual Reality Exercise Training
Description: With Aerobic Based Virtual Reality Exercise Training, participants will perform aerobic exercise training with the Xbox Kinect 360 game Your Shape Fitness Evolved 2012. Your Shape Fitness Evolved 2012 is a game that requires basic coordination and is designed to improve the fitness levels of individuals. The game is used as an entertaining aerobic training tool that includes many aerobic activities such as boxing, yoga, dancing, etc. with adjustable difficulty levels.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Aerobic Exercise Training
Description: Using a treadmill, participants will be put through an exercise training consisting of a 10-minute warm-up at 0 degree incline, a 20-30-minute (by increasing the walking time by 5 minutes at the end of the first four weeks and the beginning of the last four weeks) walking at 40-80% of the heart rate reserve (moderate-vigorous intensity) and a 10-minute cool-down period. Treadmill walking levels will be changed if necessary to ensure the targeted exercise intensity.
Study: NCT06616818

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: DASH-FV
Description: 12weeks of fruit and vegetable delivery to the home

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: nutrition counselling only
Description: nutrition counselling as part of standard of care
Study: NCT06461377

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucagon-like peptide-1 receptor agonist：Semaglutide
Description: The GLP-1RA intervention group was given subcutaneous injection of GLP-1RA for 3 months, while the control group was not given GLP-1RA intervention
Study: NCT05571033

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Spinal reflex conditioning
Description: Each participant will serve as their own control. The intervention is 30 sessions. The first 6 sessions are baseline measures of reflexes. The remaining sessions will engage participants in learning how to decrease their reflex activity in their calf muscle on the more-affected leg. Each intervention visit will involve 20 trials in which participants do not get visual feedback about their performance, then 225 trials with visual feedback.
Study: NCT05768932

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAL0891
Description: BAL0891 is a dual inhibitor of threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1)

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin is an Antineoplastic agent

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a natural product with antitumor activity

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a natural product with antitumor activity

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a natural product with antitumor activity
Study: NCT04758897

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell))
Description: Intratumoral injection only. The dosing date can be the Day 1 only or Days 1 through 5.
Study: NCT06182319

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gastrografin
Description: Administration of WSC (Gastrografin) 2 hours after placement of NGT.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Administration of Saline 2 hours after placement of NGT.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SBO Treatment Without NG Tubes
Description: Patients who decline to have NG tubes placed will be enrolled and followed with the same outcomes protocol as the other patients in the trial
Study: NCT05060562

Intervention type: OTHER
Intervention: COVID 19 positive
Description: Diagnosed as COVID 19 patient using Real-Time Polymerase Chain Reaction (RT-PCR) with the nasopharyngeal swab, or Rapid Antigen test of nasopharyngeal swab with suggestive symptoms.

Intervention type: OTHER
Intervention: COVID 19 positive
Description: Diagnosed as COVID 19 patient using Real-Time Polymerase Chain Reaction (RT-PCR) with the nasopharyngeal swab, or Rapid Antigen test of nasopharyngeal swab with suggestive symptoms.

Intervention type: OTHER
Intervention: COVID 19 negative
Description: Suspected COVID 19 patients who were tested negative using either Real-Time Polymerase Chain Reaction (RT-PCR) with the nasopharyngeal swab, or Rapid Antigen test of nasopharyngeal swab.

Intervention type: OTHER
Intervention: COVID 19 negative
Description: Suspected COVID 19 patients who were tested negative using either Real-Time Polymerase Chain Reaction (RT-PCR) with the nasopharyngeal swab, or Rapid Antigen test of nasopharyngeal swab.
Study: NCT05140915

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Messaging
Description: Peer messages, written by current and former adolescent e-cigarette users and tailored by age and readiness-to-quit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Coaching via Text
Description: Peer coaching, facilitated by texting

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gamification
Description: Gamification, designed to motivate participation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: E-Cigarette Cessation Materials
Description: Written e-cigarette cessation materials by the Research Coordinator at the time of study enrollment. The written materials will consist of two pamphlets from Journeyworks, selected based on: (1) their clear and attractive layout designed for a low-literacy audience, and (2) their providing both information re: e-cigarette use with a strong message about nicotine and nicotine addiction, E-Cigarettes: 8 Things Everyone Should Know, and support in quitting, How to Quit Vaping.
Study: NCT06424639

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Luspatercept
Description: Luspatercept (dose of 1.0 mg/kg, subcutaneous injection every 3 weeks) Cyclosporine (3-5mg/kg/day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cyclosporine
Description: Cyclosporine (3-5mg/kg/day)
Study: NCT05708066

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lavender Aromatherapy
Description: Participants will have the Bioesse lavender patch placed on the chest, according to manufacturer recommendations.~After the lavender patch has been in place for 5 minutes, the same VAS anxiety questionnaire will be provided

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Non-scented Tab
Description: A non-scented tab will be placed on the participant's chest, according to manufacturer recommendations. Participants in this group will only receive the initial VAS anxiety questionnaire.
Study: NCT05851768

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Bupivacaine 0.25%

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine + Magnesium
Description: Bupivacaine 0.25% + Magnesium

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine + Dexmedetomidine
Description: Bupivacaine 0.25% + Dexmedetomidine
Study: NCT06424639

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cyclosporine
Description: Cyclosporine (3-5mg/kg/day)
Study: NCT03598972

Intervention type: OTHER
Intervention: intervention
Description: elementary analysis

Intervention type: OTHER
Intervention: intervention
Description: elementary analysis
Study: NCT04004845

Intervention type: DRUG
Intervention: Cytotec
Description: Misoprostol 25mcg vaginal

Intervention type: DRUG
Intervention: oxytocin
Description: Oxytocin 10 IU/ml Solution for infusion

Intervention type: DEVICE
Intervention: Cervical Foley Balloon
Description: Cervical Foley will be inflated to 80cc
Study: NCT05126329

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: amcenestrant
Description: tablet for oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: amcenestrant
Description: tablet for oral use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: amcenestrant
Description: tablet for oral use
Study: NCT05012644

Intervention type: DRUG
Intervention: Palbociclib + aromatase inhibitor
Description: Palbociclib + aromatase inhibitor

Intervention type: DRUG
Intervention: Aromatase inhibitor
Description: Aromatase inhibitor
Study: NCT06214221

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Signos System
Description: The intervention involves the use of the Signos System, a combination of a proprietary software application with a continuous glucose monitor (CGM), to manage weight in overweight and obese adults.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Lifestyle Education
Description: In the Standard Lifestyle Education arm, participants receive conventional advice on diet and exercise, focusing on general healthy lifestyle habits to manage weight.
Study: NCT06631378

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transverse groin incision
Description: The transverse incision is made parallel to the inguinal ligament either superiorly or inferiorly to the skin crease directly over the femoral artery. The subcutaneous tissue is dissected in the transverse direction till Scarpaes fascia after which the dissection is performed in the longitudinal direction along the line of the vessels. The lymphatic vessels are spared as much as possible. Any damaged lymph vessels are closed with surgical clips. Damages lymph nodes are either removed or the capsule is sutured to prevent lymph leakage. In case of difficulty with proper access to the femoral arteries, the incision can be extended either medially, laterally, or vertically.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Longitudinal incision
Description: The longitudinal incision is made directly over the femoral artery from the inguinal ligament. The subcutaneous tissue is dissected along the line of the vessel sparing the lymphatic vessels as much as possible. Any damaged lymph vessels are closed with clips. Damages lymph nodes are either removed or the capsule is sutured to prevent lymph leakage.
Study: NCT06033560

Intervention type: DEVICE
Intervention: High flow nasal oxygen (HFNO, more than 15 L/min)
Description: Non-invasive respiratory support strategy

Intervention type: DEVICE
Intervention: High flow nasal oxygen (HFNO, more than 15 L/min)
Description: Non-invasive respiratory support strategy
Study: NCT06074263

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone 8mg
Description: Dexamethasone 8mg will be taken orally just prior to surgery.
Study: NCT06074263

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsule which looks identical to dexamethasone capsule
Study: NCT05605444

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single bout of exercise
Description: isometric wall squat at a knee joint angle of 100 degrees. Instruct participant to place their back against the wall with feet positioned parallel and spaced shoulder-width apart. Lower themselves down until they reached a knee joint angle of 100 degrees. Measure knee joint angle by placing a goniometer on the lateral epicondyle of the knee, in line with the femur whilst the anchor arm was in line with the lateral malleolus.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single bout of exercise
Description: isometric wall squat at a knee joint angle of 100 degrees. Instruct participant to place their back against the wall with feet positioned parallel and spaced shoulder-width apart. Lower themselves down until they reached a knee joint angle of 100 degrees. Measure knee joint angle by placing a goniometer on the lateral epicondyle of the knee, in line with the femur whilst the anchor arm was in line with the lateral malleolus.
Study: NCT06629064

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Working Memory Training
Description: Computer-administered working memory training program. WMT is a modified working memory capacity task designed to train working memory functioning. WMT is designed to contain high interference across trials and is adaptive to performance. As participants improve working memory, the task becomes more difficult.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Training
Description: The Sham condition requires participants to complete a similar computer task for the same length of time. The Sham Training is a modified working memory capacity task designed to place less demands on working memory.
Study: NCT06711315

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oral Mucosit Care Protocol
Description: The children in the intervention group were subjected to a four-stage intervention carried out by the nurse researcher. The practices in each stage were as follows.~Stage 1: Oral care protocol training to prevent oral mucositis Stage 2: Introduction and application of training material (brochure) Stage 3: Introduction and implementation of oral care calendar Stage 4: Implementation of oral care protocol
Study: NCT03921489

Intervention type: PROCEDURE
Intervention: Subchondroplasty
Description: Calcium phosphate mineral compound injected into the bone marrow lesions
Study: NCT05266352

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised exercise program
Description: A structured program consisting of range of motion, postural control, scapulothoracic strengthening, glenohumeral strengthening and dynamic stabilization exercises used in conservative treatment of rotator cuff tears will be performed for 8 weeks.~Patients will do the exercises under control of the physiotherapist in the clinic.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Home exercise program
Description: A structured program consisting of range of motion, postural control, scapulothoracic strengthening, glenohumeral strengthening and dynamic stabilization exercises used in conservative treatment of rotator cuff tears will be performed for 8 weeks.~Patients will do the exercises at home. Patients will visit the clinic every 2 weeks and progression of exercise program will be made.
Study: NCT05502211

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: induction of anaesthesia using fentanyl
Study: NCT04836351

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Concentrated rehabilitation for patients with persistent symptoms post COVID-19
Description: 3+ 1-2 days concentrated rehabilitation for patients with persistent symptoms post COVID-19 with a mobile application follow-up and physical consultations at 3 months post intervention.
Study: NCT05502211

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine IV
Description: induction of anesthesia using lidocaine
Study: NCT06629727

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR Group
Description: the experimental group was shown a video through VRG during the lithotripsy procedure.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: Patients received standard care during the procedure
Study: NCT06629662

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sleeve gastrectomy
Description: Sleeve gastrectomy with laparoscopic or robotic approach

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sleeve gastrectomy
Description: Sleeve gastrectomy with laparoscopic or robotic approach
Study: NCT05206890

Intervention type: DRUG
Intervention: fluzoparib monotherapy or combination therapy
Description: patients with epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer who underwent fluzoparib monotherapy or combination therapy
Study: NCT05380583

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CRAFT-EP
Description: CRAFT-EP is a behavioral intervention delivered via telehealth with the option for one in-person session (when local guidelines allow in-person care without masks). The coaching session topics include self-care, communication, functional analysis, positive reinforcement, treatment engagement, natural consequences, problem solving, and planning next steps. The intervention is designed for families of individuals experiencing psychosis and substance use who are enrolled or seeking enrollment in early psychosis outpatient services. Participants will be asked to complete assessments at pre-, mid- (approximately week 4), post-intervention, and a follow-up assessment approximately 12 weeks post-intervention.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TAU
Description: Participants may continue to receive their ongoing treatment, if any, which may include psychosocial and/or pharmacological interventions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: TAU
Description: Participants may continue to receive their ongoing treatment, if any, which may include psychosocial and/or pharmacological interventions.
Study: NCT04699604

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levocetirizine Dihydrochloride
Description: At the end of the HILD assessment participants will be randomized to Levocetirizine Dihydrochloride or placebo. Children will be randomized by an investigational pharmacist to add-on either Levocetirizine dihydrochloride/ Xyzal® (UCB, Inc.) immediate release oral solution 2.5mg/5ml (2.5mg in children 6-11 years of age; 5mg in children \>11 years per recommended doses) or placebo to their current asthma regimen.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06101394

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab-IRDye800
Description: Infusion of the study drug will be performed 2-5 days before the surgery: the patients will receive 100 mg of cetuximab intravenously over 30 minutes and a dose 50 mg of cetuximab-IRDye800 over 30 minutes to 1 hour.
Study: NCT05155371

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Titration of Optimal Positive End-expiratory Pressure
Description: Titration of Optimal Positive End-expiratory Pressure with two different methods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Titration of Optimal Positive End-expiratory Pressure
Description: Titration of Optimal Positive End-expiratory Pressure with two different methods
Study: NCT05473208

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Exoskeleton
Description: Lumbar assistive exoskeleton evaluation
Study: NCT06462417

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arbidol
Description: Arbidol Hydrochloride Tablets 0.2g/d for 2 weeks
Study: NCT05218850

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Butyrate
Description: Butyrate enemas will be administered once a day for 12 weeks
Study: NCT04997889

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Artificial salivary containing cumin and ginger extract
Description: The artificial salivary containing cumin and ginger extract will be used 2 g/time (3 times/day) into the mouth for 6 days. Then, the artificial salivary containing cumin and ginger extract will be stopped for 7-10 days. After that, the artificial salivary containing cumin and ginger extract will be used 2 g/time (3 times/day) into the mouth for 3 days.
Study: NCT06476327

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: experimental 1 group
Description: A camera is installed on the walker used in the training, and the recorded video is mirrored in real-time to a tablet computer. Participants can view this video through smart glasses connected to the tablet computer. A glasses strap will be used to secure the glasses, ensuring there is no interference with walking.~Participants will undergo a total of 20 training sessions, five times a week for four weeks, with each session lasting 30 minutes. Participants will have a 4-minute break during the 30-minute gait training session.~Participants will be given a period to adapt to wearing the robot, and after that, the intervention will be conducted based on each participant's individual abilities and adaptation.