TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06593444

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thalamic Ventral Intermediate-DBS
Description: Participants will undergo Thalamic Ventral Intermediate-DBS ON with the individual stimulation parameters determined in the parameter determination period, then continue to receive stimulation for the remainder of the study.
Study: NCT05546827

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical resection
Description: Surgical resection after receiving neodjuvant combination immunotherapy followed by radiation therapy.
Study: NCT06604702

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autologous Fat Injection for Rectocele
Description: In this procedure, autologous fat is harvested from the patient\&#39;s lower abdomen using a multiport cannula. The fat is then processed via centrifugation to separate the viable fat cells, which are emulsified into nanofat. This nanofat is injected into the submucosal layer of the rectocele through the posterior vaginal wall, using an anoscope for guidance. The procedure is intended to reinforce the rectovaginal fascia, alleviate rectocele symptoms such as obstructive defecation and vaginal bulge, and reduce prolapse recurrence.
Study: NCT06587880

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chlorhexidine Gluconate
Description: Prescribed for 7 days period 2 times a day starting 24 hours post-extraction, the patient is instructed to pour 10 ml of the mouthwash into a measuring cup, rinse for 1 minute at an alternative time to teeth brushing. Do not eat or drink for 30 min after use.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bone Bioactive Liquid
Description: Prescribed for 7 days period 2 times a day starting 24 hours post-extraction.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic Acid mouthwash
Description: Prescribed for 7 days period 3-4 times a day starting 24 hours post-extraction, the patient is instructed to pour 20 ml of the mouthwash into a measuring cup and rinse for 1 minute, at an alternative time to teeth brushing. Do not eat or drink for 30 mins after use.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Warm Saline Mouth Rinse
Description: Prescribed for 7 days period 2 times a day starting 24 hours post-extraction.
Study: NCT06586944

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nursing Practices Based On Roy Adaptation Model Integrated With Virtual Reality
Description: After the research groups were formed, a six-session interview programme was created for the participants included in the experimental group (Table...). In the sessions, nursing and psychiatric nursing interventions (psychoeducation, relaxation, awareness, effective coping, cognitive restructuring) based on the Roy Adaptation Model were carried out for the negative situations caused by anxiety and anxiety experienced by individuals. Subjective goals were determined for adaptive or maladaptive behaviour, attitude and thought patterns caused by anxiety-causing stimulus(s) and appropriate nursing interventions from the Nursing Interventions Classification System (NIC) were applied for these goals.Virtual reality-based intervention was effectively used as an important intervention tool in the implementation of the interventions and in the evaluation of the implemented interventions in four sessions of a total of six sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Roy Adaptation Model
Description: After the research groups were formed, a six-session interview programme was created for the participants included in the experimental group. In the sessions, nursing and psychiatric nursing interventions (psychoeducation, relaxation, awareness, effective coping, cognitive restructuring) based on the Roy Adaptation Model were carried out for the negative situations caused by anxiety and anxiety experienced by individuals. Subjective goals were determined for adaptive or maladaptive behaviour, attitude and thought patterns caused by anxiety-causing stimulus(s) and appropriate nursing interventions from the Nursing Interventions Classification System (NIC) were applied for these goals
Study: NCT06591663

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Therapy Rating Scale (CTRS)
Description: CBT is the Cognitive Therapy Rating Scale (CTRS), an important assessment tool designed to assess the quality and effectiveness of cognitive therapy sessions.~Mental health professionals, such as therapists and psychologists, commonly use the CTRS to evaluate various aspects of a therapy session. This includes the extent to which the therapist adheres to CBT principles, their skill in applying cognitive and behavioral techniques, their ability to develop a therapeutic relationship with the client, and the overall quality of the session. The scale may also include specific criteria or items that another trained therapist or researcher observes based on their observations during the therapy session (Pingol, 2023).
Study: NCT06587126

Intervention type: DEVICE
Intervention: Curie Artificial Intelligence (AI) cough monitor
Description: All patients are given nighttime cough monitors for home use for 3-4 months

Intervention type: DEVICE
Intervention: Curie Artificial Intelligence (AI) cough monitor
Description: All patients are given nighttime cough monitors for home use for 3-4 months
Study: NCT06588049

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beet Root
Description: Beet Root powder used as a mouth rinse in suspension with water

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Water
Description: Water used as a mouth rinse
Study: NCT06594978

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dual-site anodal tDCS over the M1
Description: M1: motor cortex

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dual-site anodal tDCS over the DLPFC
Description: DLPFC: dorsolateral prefrontal cortex

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tDCS
Description: sham stimulation
Study: NCT06595355

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bevacizumab with oral curcumin
Description: According to the recommendation of the American Association of Ophthalmologists, intravitreal injection of bevacizumab with a standard dose of 1.25mg/0.05ml in each group will be performed three times consecutively at one-month intervals. In the simultaneous intervention group, patients will take daily curcumin tablets (sinacurcumin product) at a dose of 40 mg twice a day for three months (at the same time as the start of bevacizumab intravitreal injection treatment).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: bevacizumab with oral placebo
Description: Intravitreal injection of bevacizumab with a standard dose of 1.25mg/0.05ml in each group will be performed three times consecutively at one-month intervals. In the control group, patients will be taking daily placebo tablets twice a day for three months (at the same time as the start of bevacizumab intravitreal injection treatment).
Study: NCT06599814

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: vital pulp therapy
Description: vital pulp therapy using two bioactive materials TheraCal and RetroMTA as direct pulp caping materials conventionally and test using Diode laser before application of these materials

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: vital pulp therapy
Description: vital pulp therapy using two bioactive materials TheraCal and RetroMTA as direct pulp caping materials conventionally and test using Diode laser before application of these materials

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: vital pulp therapy
Description: vital pulp therapy using two bioactive materials TheraCal and RetroMTA as direct pulp caping materials conventionally and test using Diode laser before application of these materials

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: vital pulp therapy
Description: vital pulp therapy using two bioactive materials TheraCal and RetroMTA as direct pulp caping materials conventionally and test using Diode laser before application of these materials
Study: NCT06600529

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photo-Biomodulation
Description: Application at acupuncture points for 20 seconds each week. using 810nm Laser probe

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous PRP
Description: IV injection of Autologous Plasma Rich Platelets (PRP) on Days 0, 15, 30, and 45.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Exosome Therapy
Description: IV injection of Umbilical Cord-Derived Exosomes at laser acupuncture points Umbilical Cord-Derived Exosomes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Care (in control arm)
Description: Routine conventional including Applied Behavioral Analysis (ABA) for Autism Spectrum Disorder (ASD)
Study: NCT06596980

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Poppins Clinical
Description: Poppins Clinical is a software as a medical device that combines a musical and cognitive training program and written language training program.
Study: NCT06590831

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactoferrin
Description: to compare between efficacy of lactoferrin alone and lactoferrin with iron for treatment of iron deficiency anemia during 3rd trimester of pregnancy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactoferrin
Description: to compare between efficacy of lactoferrin alone and lactoferrin with iron for treatment of iron deficiency anemia during 3rd trimester of pregnancy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactoferrin
Description: to compare between efficacy of lactoferrin alone and lactoferrin with iron for treatment of iron deficiency anemia during 3rd trimester of pregnancy
Study: NCT06603441

Intervention type: DIAGNOSTIC_TEST
Intervention: Samsung Galaxy Watch
Description: Samsung Galaxy Watch technology to monitor sleep patterns, oxygen saturation, PPG, and heart rate variability amongst other physiologic parameters.
Study: NCT06599359

Intervention type: BEHAVIORAL
Intervention: BLISS Questionnaire
Description: After extensive literature review and review from the IRB of the Lebanese University. A questionnaire was developed to assess the Intention to leave, job stress, burnout, and job satisfaction among pharmacists in Lebanon~The following sections will be considered:~* Socio-economic characteristics~* Work-related characteristics~* Job stress assessment (Likert scale)~* Burnout assessment (Likert scale)~* Intention to Leave assessment (Likert scale)
Study: NCT06593028

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Veggie Vouchers pilot
Description: This intervention aims to increase awareness and use of a Supplemental Nutrition Assistance Program (SNAP) fruit and vegetable incentive program in South Carolina among families with young children experiencing food insecurity. To do so, brief education about this SNAP program is delivered by pediatricians to caregivers during well-child visits. Subsequently, caregivers are given 3 free produce boxes as a free trial of this program to incentivize first time use.
Study: NCT04895644

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No Hard Collar
Description: The patient in the intervention arm will not wear a Hard Collar for 12 weeks post injury
Study: NCT05978167

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate
Description: Oral administration of 20 mg Methylphenidate

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methylphenidate
Description: Oral administration of 20 mg Methylphenidate

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Memory reconsolidation
Description: Retrieval of drug-cue memories before extinction.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Memory reconsolidation
Description: Retrieval of drug-cue memories before extinction.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo pill

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo pill
Study: NCT05446272

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NIV-NAVA
Description: Infants in the intervention arm will be managed with non-invasive neurally adjusted ventilatory assist (NIV-NAVA) using FDA-approved servos with associated FDA-approved Edi catheter.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NS-NIPPV
Description: Infants in the active comparator arm will be treated with non-synchronized non-invasive positive pressure ventilation (NIPPV) through FDA-approved ventilators currently in use at each site.
Study: NCT06599268

Intervention type: BEHAVIORAL
Intervention: Survey using a questionnaire.
Description: Questionnaire to assess the barriers and enablers for women reaching top executive positions in pharmaceutical companies and pharmacies~The following sections will be considered:~* General Characteristics of the Participants~* Work-related characteristics~* Barriers faced by women to reach top executive positions (Likert scale)~* Enablers for women to reach top executive positions (Likert scale)~* Conception of women in the pharmaceutical sector (Likert scale)
Study: NCT06602869

Intervention type: OTHER
Intervention: Scheduled visit (V1)
Description: During the scheduled visit (V1), as part of routine care, a blood draw will be performed. On this occasion, an additional 7 ml tube will be collected to perform serology and culture. This will help define the group (NTM+ Cases/NTM- Controls) and measure cellular biomarkers.

Intervention type: OTHER
Intervention: Scheduled visit (V1)
Description: During the scheduled visit (V1), as part of routine care, a blood draw will be performed. On this occasion, an additional 7 ml tube will be collected to perform serology and culture. This will help define the group (NTM+ Cases/NTM- Controls) and measure cellular biomarkers.
Study: NCT06599762

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: Tranexamic acid 1 gram orally twice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo orally twice daily
Study: NCT06592859

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: NMN
Description: NMN Arm participants took one capsule (containing 350mg NMN or placebo) with breakfast daily for one year.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Placebo arm participants took one capsule (appearance and odor are the same as NMN) with breakfast daily for one year.
Study: NCT04971954

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine gum
Description: Nicotine (6 mg) will be administered in the form of polacrilex gum that is available as an over-the-counter medication

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo gum
Description: The placebo will also be a commercially available gum that resembles the nicotine gum in flavor, size, shape, color, and texture.
Study: NCT06588959

Intervention type: OTHER
Intervention: validity and reliability study
Description: Determination of strength, endurance and exercise capacity of the upper extremities is an important issue in scleroderma management. 6PBRT, which is one of the tests serving this purpose, has been found to be valid and reliable in patients with chronic obstructive pulmonary disease and asthma, but when the literature is reviewed, it is seen that 6PBRT has not been studied in patients with scleroderma. This study was planned as a non-interventional safety study. The study will investigate the validity and reliability of 6PBRT in patients with scleroderma. In this context, the test will be performed 2 times with a 1-hour rest break. Dyspnea and fatigue will be assessed using the Borg scale and muscle oxygenation, heart rate and blood pressure will be recorded before and after 6PBRT. The level of dyspnea and fatigue and baseline values of heart rate will be checked before the second trial to ensure patients are stable. All assessments will be performed by the same physiotherapist.
Study: NCT06591559

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Permobil Explorer Mini
Description: The Explorer Mini (Permobil AB, Sweden) is a commercially available, FDA approved powered mobility device intended for young children between 12-36 months of age with mobility limitations (weight limit: 35 lbs; height limit: 39.4 inches). It is lightweight (52 lbs. including battery) and fits in most automobiles (length: 25 inches; width: 19 inches; adjustable height: 29-37 inches). The Explorer Mini runs on a 12-volt battery with a driving range of 3.5 miles and a maximum speed of 1.5 mph, is controlled via a joystick with a 360-degree turning radius, has proportional speed control with 5 speed options, and can be used in a seated or standing position.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Permobil Explorer Mini
Description: The Explorer Mini (Permobil AB, Sweden) is a commercially available, FDA approved powered mobility device intended for young children between 12-36 months of age with mobility limitations (weight limit: 35 lbs; height limit: 39.4 inches). It is lightweight (52 lbs. including battery) and fits in most automobiles (length: 25 inches; width: 19 inches; adjustable height: 29-37 inches). The Explorer Mini runs on a 12-volt battery with a driving range of 3.5 miles and a maximum speed of 1.5 mph, is controlled via a joystick with a 360-degree turning radius, has proportional speed control with 5 speed options, and can be used in a seated or standing position.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Portable Mobility Aid for Children (PUMA)
Description: The Portable Mobility Aid for Children (PUMA; Enliten LLC) is a portable canopy system that utilizes an overhead support rail structure and a counterweight. The rail structure consists of two rigid parallel beams that mount to the canopy structure and one perpendicular mobile beam that allows for freedom of movement in one direction. Freedom of movement in the opposite direction is achieved by a system of pulleys along the movable beam that connects the harness to a counterweight. The counterweight provides a passive vertical force, counteracting gravity. The PUMA provides 2-dimensional mobility support over 81 ft2 (9 ft x 9 ft). The overhead bar is connected at 4 points to a child-worn harness. Children are free to move through many postures including sitting, crawling, standing, and walking.
Study: NCT06587620

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tranexamic acid
Description: Start IV infusion of a loading dose of tranexamic acid 10 mg/kg completed to 50 ml saline over 10 min before induction of anesthesia. IV infusion of tranexamic acid at a dose of 1 mg/kg/h immediately after induction till 15 min before the end of surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Start IV infusion of a loading dose of dexmedetomidine 1ug/kg completed to 50 ml saline over 10 min before induction of anesthesia. IV infusion of dexmedetomidine 0.3-0.7 µg/kg/h immediately after induction to maintain Mean Arterial Pressure (MAP) between 60-70 mmHg till 15 min before the end of surgery.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline (NaCl 0,9 %) (placebo)
Description: IV infusion of 50 ml saline over 10 min before induction of anesthesia. IV saline infusion immediately after induction till 15 min before the end of surgery.
Study: NCT06600594

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Beginners dance training
Description: Trainings will be conducted twice a week for two hours. The training includes a general warm-up, polishing the steps, including regional dances, and then dancing entire dance routines.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Experience dance training
Description: Trainings will be conducted twice a week for two hours. The training includes a general warm-up, polishing the steps, including regional dances, and then dancing entire dance routines.
Study: NCT06588452

Intervention type: OTHER
Intervention: RECTIFIER - a generative artificial intelligence screening tool
Description: RECTIFIER is a large-language model based, generative artificial intelligence-enabled inclusion and exclusion criteria assessment tool.

Intervention type: OTHER
Intervention: Manual clinical trial screening by study staff
Description: The current gold standard - study staff manually review potentially eligible patients through chart review.
Study: NCT06604585

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parenthood - a journey together. Digital tool to increase security in parenthood, a way to promote public health..
Description: The project involved the development of an internet-based parental support program to be delivered via the national Support and Treatment (Sob) platform and used in primary care to enhance traditional parental support within child healthcare, as needed. The innovation has been developed in collaboration with the Innovation Fund in Västra Götaland. The aim is to increase the experience of parental competence and a sense of security in parenting by reflecting on attitudes and approaches in interaction with the child through an interactive, digital parental support program. The four themes in the parental support program, Parenthood a journey together, are named: Being a good enough parent, understanding one's child, interacting with one's child, and meeting daily challenges as a parent regarding food, sleep, play, screen time, and physical activity. The four modules will include explanatory and psychoeducational texts, written exercises, videos, and homework.
Study: NCT06609460

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CD388 Injection
Description: CD388 liquid for injection

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CD388 Injection
Description: CD388 liquid for injection

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CD388 Injection
Description: CD388 liquid for injection

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match
Study: NCT06147037

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FPI-2053
Description: FPI-2053 is a bispecific antibody that targets EGFR and cMET

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [111In]-FPI-2107
Description: \[111In\]-FPI-2107 is an imaging agent in which indium-111 is conjugated to FPI-2053.~Participants will have a fixed dose of \[111In\]-FPI-2107 followed by imaging scans (with or without pre-administration of FPI-2053).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [225Ac]-FPI-2068
Description: \[225Ac\]-FPI-2068 is a radiopharmaceutical therapy in which an alpha emitter, actinium-225, is conjugated to FPI-2053.~Participants will be dosed through IV administration every 56 days for up to 3 cycles of the Treatment Period.
Study: NCT06597864

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Seven-step phenomenological psychotherapy for self-disorders
Description: Phenomenological exploration of anomalous self-experiences, meaning attributions and behavioral consequences. Psychoeducation. Dialogical approach focusing on self-narratives, searching for new meaning and understanding of self-disorders