TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05139342

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: expiratory muscle strentgh training (EMST)
Description: All patients undergo EMST training, and results will be compared between groups.~After individual adjustment of the EMST device for each patient, the patient receives speeach adn instruction from a speech and language pathologist on the correct use of the EMST device. The intervention regime then consists of 5x5 breaths per day for 14 consecutive days.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: expiratory muscle strentgh training (EMST)
Description: All patients undergo EMST training, and results will be compared between groups.~After individual adjustment of the EMST device for each patient, the patient receives speeach adn instruction from a speech and language pathologist on the correct use of the EMST device. The intervention regime then consists of 5x5 breaths per day for 14 consecutive days.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: expiratory muscle strentgh training (EMST)
Description: All patients undergo EMST training, and results will be compared between groups.~After individual adjustment of the EMST device for each patient, the patient receives speeach adn instruction from a speech and language pathologist on the correct use of the EMST device. The intervention regime then consists of 5x5 breaths per day for 14 consecutive days.
Study: NCT04873726

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Tape® aplication
Description: Magnetic tape® is applied without creating any tension on the lumbar paravertebral skin to assess changes in pupil size

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Tape® aplication
Description: Magnetic tape® is applied without creating any tension on the lumbar paravertebral skin to assess changes in pupil size

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Tape® aplication
Description: Magnetic tape® is applied without creating any tension on the lumbar paravertebral skin to assess changes in pupil size

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Kinesiology Tape
Description: Kinesiology tape is applied without creating any tension on the lumbar paravertebral skin to assess changes in pupil size

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Kinesiology Tape
Description: Kinesiology tape is applied without creating any tension on the lumbar paravertebral skin to assess changes in pupil size

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Kinesiology Tape
Description: Kinesiology tape is applied without creating any tension on the lumbar paravertebral skin to assess changes in pupil size
Study: NCT05731310

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Angong Niuhuang Pill
Description: Take Angong Niuhuang pill half a pill/day； Angong Niuhuang pill combined with music scalp acupuncture group These operations last for 4 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Angong Niuhuang Pill
Description: Take Angong Niuhuang pill half a pill/day； Angong Niuhuang pill combined with music scalp acupuncture group These operations last for 4 weeks
Study: NCT05589974

Intervention type: DRUG
Intervention: Verteporfin
Description: Chronic CSC are receiving one treatment before the observation period.
Study: NCT05148728

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endoscopic fulguration
Description: already included. WE will use Storz monopolar device for fulguration
Study: NCT05605353

Intervention type: DIAGNOSTIC_TEST
Intervention: Faecal microbiota sampling and blood sampling
Description: There is no intervention in this study. We will obtain faeces and blood from the recruited patients and assess the microbiota and their metabolites therein. This is an observational work

Intervention type: DIAGNOSTIC_TEST
Intervention: Faecal microbiota sampling and blood sampling
Description: There is no intervention in this study. We will obtain faeces and blood from the recruited patients and assess the microbiota and their metabolites therein. This is an observational work

Intervention type: DIAGNOSTIC_TEST
Intervention: Faecal microbiota sampling and blood sampling
Description: There is no intervention in this study. We will obtain faeces and blood from the recruited patients and assess the microbiota and their metabolites therein. This is an observational work
Study: NCT06184048

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Intra-Articular knee injection of LC-PRP
Description: Blood Collection 45mL, Processed Neutrophil-Poor PRP, 2 Injections at day 0 and 3 weeks.
Study: NCT05462574

Intervention type: OTHER
Intervention: No Intervention
Description: No Intervention
Study: NCT06472739

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GM-CSF
Description: GM-CSF mouthwash four times per day at radiotherapy initiate, during the whole radiotherapy phase
Study: NCT05227716

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Perioperative magnesium sulfate
Description: Administration of magnesium sulfate as an adjunct in anesthesia

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Perioperative magnesium sulfate
Description: Administration of magnesium sulfate as an adjunct in anesthesia
Study: NCT04688632

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ampreloxetine <Dose A>
Description: Ampreloxetine \<Dose A\> will be administered as 1 tablet of \<Dose A\> and 3 tablets of Ampreloxetine Placebo.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ampreloxetine <Dose B>
Description: Ampreloxetine \<Dose B\> will be administered as 4 tablets of \<Dose A\>

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ampreloxetine Placebo
Description: Ampreloxetine Placebo will be administered as 4 tablets of placebo. The placebo tablet will match (in appearance) the ampreloxetine \<Dose A\> tablet.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ampreloxetine Placebo
Description: Ampreloxetine Placebo will be administered as 4 tablets of placebo. The placebo tablet will match (in appearance) the ampreloxetine \<Dose A\> tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ampreloxetine Placebo
Description: Ampreloxetine Placebo will be administered as 4 tablets of placebo. The placebo tablet will match (in appearance) the ampreloxetine \<Dose A\> tablet.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin
Description: Moxifloxacin will be administered orally as a single tablet.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin
Description: Moxifloxacin will be administered orally as a single tablet.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin Placebo
Description: Moxifloxacin placebo will be administered orally as a single tablet. The placebo tablet will match (in appearance) the moxifloxacin tablet.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin Placebo
Description: Moxifloxacin placebo will be administered orally as a single tablet. The placebo tablet will match (in appearance) the moxifloxacin tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxifloxacin Placebo
Description: Moxifloxacin placebo will be administered orally as a single tablet. The placebo tablet will match (in appearance) the moxifloxacin tablet.
Study: NCT05782517

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Supraglottic Airway Device
Description: Placement of an I-gel Supraglottic Airway Device.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Endotracheal Tube
Description: Placement of an Endotracheal Tube.
Study: NCT05218694

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CCTA guided focused coronary angiography examination.
Description: Focused examination based on Images from CCTA, by choice of optimal catheter used and projection.
Study: NCT06208501

Intervention type: DIAGNOSTIC_TEST
Intervention: Urine sample for proteomic analysis
Description: Urine sample for proteomic analysis in screen visit (before renal denervation procedure).

Intervention type: DIAGNOSTIC_TEST
Intervention: ABPM
Description: ABPM in screen visit and 3 months after renal denervation procedure.

Intervention type: DIAGNOSTIC_TEST
Intervention: OBPM
Description: OBPM in screen visit and 3 months after renal denervation procedure.
Study: NCT06077175

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hand massage group
Description: Each individual will receive a 10-minute hand massage, 5 minutes for each hand. Since the speed and number of repetitions of the massage movements should be at normal frequency, the massage will be performed at a speed that does not disturb the individual, is not stimulating and has a calming effect, and will not tire the practitioner. In the massage, effleurage (stroking) and friction (circular rubbing) movements will be used, which have a circulation-supporting and tissue-relaxing effect. Evaluations will be made within 30 minutes after the hand massage.
Study: NCT05079971

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Group B: aEEG with concurrent multichannel (full) continuous cEEG review by clinical neurophysiology
Description: In group B, the standart-care equivalent aEEG review is undertaken by NICU staff via a 2-channel display. In addition to the standard care, concurrent full EEG is reviewed remotely with regular feedback by a specialist trained clinical neurophysiologist. The clinical neurophysiology reports only on seizure burden, no information or direction is provided regarding clinical management.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Group B: aEEG with concurrent multichannel (full) continuous cEEG review by clinical neurophysiology
Description: In group B, the standart-care equivalent aEEG review is undertaken by NICU staff via a 2-channel display. In addition to the standard care, concurrent full EEG is reviewed remotely with regular feedback by a specialist trained clinical neurophysiologist. The clinical neurophysiology reports only on seizure burden, no information or direction is provided regarding clinical management.
Study: NCT05652127

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mightier
Description: Mightier is an app-based biofeedback video game that utilizes heart rate (HR) monitoring during game play to teach and facilitate practice of emotional regulation skills in children ages 6-14
Study: NCT05346029

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle intervention
Description: Resistance training and nutritional counseling
Study: NCT06728371

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methadone
Description: 0.2mg/kg intravenous methadone given at induction

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: 0.2mg/kg intravenous morphine given at induction
Study: NCT05981846

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: BIMERVAX
Description: One dose of booster vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BIMERVAX
Description: One dose of booster vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SIIV
Description: One dose

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: SIIV
Description: One dose
Study: NCT05261906

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LIBERATE
Description: Five bi-weekly, followed by three monthly, one-hour videoconferencing group education classes via Microsoft Teams video platform will be offered. Participants will be given the choice to communicate with the LIBERATE clinical team (exercise specialist, MD, and/or RN) weekly between the group classes using their preferred method of communication i.e., email.~Classes will offer FreeStyle® Libre-assisted behavioural coaching (i.e., nutrition and exercise). FreeStyle® Libres will be used during the first three months of the program and optionally in the last three months of the intervention. The FitBit Inspire 2™ monitors will be worn for six months. Participants are provided the option to receive individualized aerobic and resistance training prescriptions.
Study: NCT06367543

Intervention type: DIAGNOSTIC_TEST
Intervention: Time in therapeutic range of vital parameters
Description: Treatment adherence on NICU to the following vital parameters:~1. Temperature (T\<37,5°C) (every 4 hours during the first 96 h after admission to neurocritical care unit)~2. systolic blood pressure ICD-10 (International Statistical Classification of Diseases 10th Revision) (I60, 161 \& 162): 100-140 mmHg ICD-10 (I63): 120-180 mmHg (every 4 hours during the first 96 h after admission to neurocritical care unit)~3. Mean arterial blood pressure (MAP: 60-90 mmHg) (every 4 hours during the first 96 h after admission to neurocritical care unit)~4. Arterial oxygen partial pressure (paO2: 75 - 100 mmHg) (every 4 hours during the first 96 h after admission to neurocritical care unit)~5. Arterial carbon dioxide partial pressure (paCO2: 35 - 45 mmHg). (every 4 hours during the first 96 h after admission to neurocritical care unit)~6. Blood glucose (BG: 80-180 mg/dL). (every 4 hours during the first 96 h after admission to neurocritical care unit)
Study: NCT05041400

Intervention type: OTHER
Group type: OTHER
Intervention: Evaluation of the strength of knee flexors and extensors
Description: Each participant will benefit from a clinical evaluation and an evaluation of the strength of knee flexors and extensors using an isokinetic dynamometer after a 10-minute warm up.
Study: NCT04968496

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food Secure Group
Description: Weekly meals (five breakfast and five lunch meals) will be provided to all children randomized to this group to prevent the onset of summertime food insecurity
Study: NCT06729177

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategic and Interactive Signing Instruction
Description: Evidence-based instructional methods, grounded in cognitive, sociocultural, and linguistic theories, are applied to interventions that support sign language development in deaf children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategic and Interactive Signing Instruction
Description: Evidence-based instructional methods, grounded in cognitive, sociocultural, and linguistic theories, are applied to interventions that support sign language development in deaf children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategic and Interactive Signing Instruction
Description: Evidence-based instructional methods, grounded in cognitive, sociocultural, and linguistic theories, are applied to interventions that support sign language development in deaf children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strategic and Interactive Signing Instruction
Description: Evidence-based instructional methods, grounded in cognitive, sociocultural, and linguistic theories, are applied to interventions that support sign language development in deaf children.
Study: NCT03503058

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PfSPZ Vaccine
Description: Radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum sporozoites (PfSPZ Vaccine)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PfSPZ Challenge under chloroquine (CQ) chemoprophylaxis
Description: Infectious, aseptic, purified, cryopreserved Plasmodium falciparum sporozoites (PfSPZ Challenge) administered under CQ chemoprophylaxis~Loading Dose: 10 mg/kg of CQ base (will be orally administered as a single loading dose to the participant by the study staff via directly observed therapy on PfSPZ-CVac Day -2.~Weekly Dose: Subsequent doses of maintenance dose CQ (5 mg/kg CQ base) will be given weekly as a single dose, with the last dose 5 days after the last dose of PfSPZ Challenge.
Study: NCT05883514

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational interviewing
Description: According to the Miller and Rollnick principles, the framework of the motivational interviewing group's sessions was taken from the workbook of the intervention's six sessions of motivational interviewing. A researcher recruited participants in groups of 7 patients for six sessions of 60-90 minutes each (two sessions per week). The training sessions covered topics like stress alleviation, appropriate drug usage, quitting smoking, regular physical activity, healthy eating habits, and regular physical activity. Patients in the control group got standard treatment for PPM, including education on proper medication usage, nutrition, and exercise, as well as regular checking.
Study: NCT03503058

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: 0.9% Sodium chloride

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: 0.9% Sodium chloride

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Chloroquine chemoprophylaxis alone
Description: Loading Dose: 10 mg/kg of CQ base (will be orally administered as a single loading dose to the participant by the study staff via directly observed therapy on NS Day -2.~Weekly Dose: Subsequent doses of maintenance dose CQ (5 mg/kg CQ base) will be given weekly as a single dose, with the last dose 5 days after the last dose of NS.
Study: NCT05559320

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ride-on-toy navigation training
Description: The training program will involve a set of activities where children will be encouraged to drive a joystick-operated ride-on-toy to navigate through their physical environment. The training will involve will involve progressively challenging multi-directional navigational games such as shape mazes, treasure hunts, relay races, and obstacle courses that will require children to use their affected arm skillfully to navigate through the courses.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Upper extremity functional training
Description: In addition to the navigation practice, along the multi-directional courses, children will complete tasks at multiple stations that will involve both gross and fine motor activities. The goal of the training will be to use their arm for functional goal-directed tasks and games that will involve elements of reaching, grasping, in-hand manipulation, and release. We will use props such as balls, bean bags, cups, cones, and small toys to practice skills such as catching, throwing, picking up, pushing, pulling, opening, closing, etc.
Study: NCT05447286

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NYX-783
Description: This study proposes to examine the safety, tolerability, and pharmacokinetics (PK) of NYX-783 at 50 mg and 150 mg doses versus Placebo (PBO) in combination with acute Oxycodone 15 mg and 30 mg in an inpatient randomized, cross-over study over 6 experimental sessions.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NYX-783
Description: This study proposes to examine the safety, tolerability, and pharmacokinetics (PK) of NYX-783 at 50 mg and 150 mg doses versus Placebo (PBO) in combination with acute Oxycodone 15 mg and 30 mg in an inpatient randomized, cross-over study over 6 experimental sessions.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: This study proposes to examine the safety, tolerability, and pharmacokinetics (PK) of NYX-783 at 50 mg and 150 mg doses versus Placebo (PBO) in combination with acute Oxycodone 15 mg and 30 mg in an inpatient randomized, cross-over study over 6 experimental sessions.
Study: NCT05591196

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-invasive Electrical Spinal Cord Stimulation
Description: Electrical stimulation of the spinal cord using surface electrodes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Activity Based Rehabilitation
Description: Exercise therapy targeting paralyzed hand and arm

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activity Based Rehabilitation
Description: Exercise therapy targeting paralyzed hand and arm
Study: NCT05023213

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Warna-Warni Waktu
Description: Six videos and eighteen reinforcer activities
Study: NCT06496737

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate-Intensity Interval Training (MIIT)
Description: Moderate-Intensity Interval Training (MIIT) is developed by university badminton coaches, three times a week for 12 weeks

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-Intensity Interval Training (HIIT)
Description: High-Intensity Interval Training (HIIT) is developed by university badminton coaches, three times a week for 12 weeks
Study: NCT05825053

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gait adaptability training
Description: Over a span of 1 year participants will receive 3 one hour, single sessions at 3, 6 and 9 months following baseline assessment, of gait adaptability training, using the C-mill (an instrumented treadmill with augmented reality). Several aspects of gait adaptability, such as obstacle avoidance, accelerating/decelerating and precision stepping, will be trained.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based exercise training
Description: Participants will receive tailored exercise through an online platform targeting gait adaptability. Participants are instructed to train at a minimum of 60 minutes per week, with a frequency of 2 sessions per week. Participants will be supported through tele-consultations on a monthly basis for the first 3 months and bi-monthly for the remaining time of the study. These consultations are focused on technical support, on ways to ensure training progression and to encourage adherence to the program.
Study: NCT06015100

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inetetamab plus pyrotiniband and capecitabine
Description: Inetetamab plus pyrotiniband and capecitabine
Study: NCT06516432

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Parasternal block
Description: In the case-control groups, patients with elevated serum lactate levels above 2 mmol/L and those who remained below this limit will be identified.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Requirement of total dose regarding fentanyl
Description: In case-control groups, obtain measurement of total postoperative fentanyl requirement.
Study: NCT04893161

Intervention type: DRUG
Group type: OTHER
Intervention: Belimumab
Description: All patients with SLE will be enrolled in one year and administrated belimumab 10mg/kg intravenous infusion over 1 hour on days 0, 14, and 28, and every 28 days through week 48.
Study: NCT05675163

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin K2
Description: (K2VITAL® 1% MCT Oil)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin K2
Description: (K2VITAL® 1% MCT Oil)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sunflower oil

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Sunflower oil
Study: NCT05207865

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimegepant
Description: rimegepant ODT 75mg daily
Study: NCT05503498

Intervention type: OTHER
Intervention: DATA RECORDING
Description: RECORD PLASMA FIBRI LEVELS AFTER FIBRINOGEN ADMINISTRATION