TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06286423

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine 0.6 mg
Description: Colchicine treated subjects will take 0.6mg of drug 2x per day (1 time if kidney disease is present) for 14 days, then will take 0.6mg of drug 1x per day (or every other day if kidney disease is present) for 76 +/1 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Control/Placebo group
Description: Placebo treated subjects will take 0.6mg of placebo 2x per day (1 time if kidney disease is present) for 14 days, then will take 0.6mg of placebo1x per day (or every other day if kidney disease is present) for 76 +/1 days.
Study: NCT06358014

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fematon (estradiol/estradiol-norethindrone acetate combination tablet package)+SSRIs
Description: In the combination group, eligible subjects will receive 1 tablet/day of estradiol/estradiol-norethindrone acetate combination tablet for 8 weeks. The estradiol/estradiol-norethindrone acetate combination tablet will be taken orally before bedtime, 1 tablet/day (trade name: Fematon, Abbott Laboratories, USA, this product is a combination package, with estradiol 1 mg in the first 14 days of each treatment cycle, and estradiol 1 mg and norethindrone acetate 10 mg in the last 14 days of each treatment cycle). This study uses SSRIs class drugs, including fluoxetine, paroxetine, fluvoxamine, sertraline, citalopram, and escitalopram.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SSRIs
Description: This study uses SSRIs class drugs, including fluoxetine, paroxetine, fluvoxamine, sertraline, citalopram, and escitalopram, with no specific restrictions on the type of drugs. During the study, medication doses will be quantitatively adjusted based on the results of each visit assessment combined with drug concentrations.
Study: NCT04797195

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CKD-PD app with home monitoring equipment
Description: use home monitoring equipment to measure blood pressure, body weight, and dialysate fluid volume and record in CKD-PD app
Study: NCT06413004

Intervention type: OTHER
Group type: OTHER
Intervention: Elimination and re-introduction of CLE or COLAP positive food item(s)
Description: Elimination (4 weeks) and re-introduction (4 weeks) of all CLE or COLAP positive food item(s)
Study: NCT05051956

Intervention type: DRUG
Intervention: Palbociclib 125mg and Ribociclib 600 mg
Description: Administration of Palbociclib or Ribociclib
Study: NCT06518759

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional chest techniques
Description: patients will receive traditional chest techniques in the form of percussion and vibration, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional chest techniques
Description: patients will receive traditional chest techniques in the form of percussion and vibration, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks
Study: NCT05395221

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Guided Mediation Virtual Reality App
Description: Guided Meditation Virtual Reality App uses over 40 lush environments with 30 hours of guided meditations on Anxiety, Depression, Maternity, Resilience, Sleep, or Zen and 200 relaxing audio tracks using Virtual reality.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Guided Mediation Virtual Reality App
Description: Guided Meditation Virtual Reality App uses over 40 lush environments with 30 hours of guided meditations on Anxiety, Depression, Maternity, Resilience, Sleep, or Zen and 200 relaxing audio tracks using Virtual reality.
Study: NCT05946967

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Biofeedback with TENS
Description: Constipation patients will be given biofeedback treatment along with transcutaneous electrical stimulation (TENS) of posterior tibial nerve

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Biofeedback only
Description: Constipation patients will be given biofeedback treatment only
Study: NCT05749835

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thoracic Manipulation and Sustained Natural Apophyseal Glides and conventional therapy
Description: After the segmental mobility examination of thoracic spine, the therapist will apply a high-velocity, end range screw thrust to a restricted segment of the thoracic spine as described by Maitland.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sustained Natural Apophyseal Glides and conventional therapy
Description: Position of therapist: stands beside the patient, while his\\her head is cradled between your body and your right forearm (when you stand at his\\her right side). Gentle pressure is now applied in a ventral direction on the spinous process of C7 while the skull remains still due to the control of your right forearm. (The really gentle moving force to do this comes from your left arm via the thenar eminence over the little finger on the spine of C7).
Study: NCT06518759

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Glossopharyngeal breathing exercise
Description: patients will receive Glossopharyngeal breathing exercise, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diaphragmatic breathing exercise
Description: patients will receive diaphragmatic breathing exercise, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks.
Study: NCT05844553

Intervention type: DEVICE
Intervention: Measurement of inhaled measuring hydrogen peroxide in exhaled breath
Description: Participant exhales in to device
Study: NCT04514302

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo of saline solution of equal volume and infusion. Content of the infusion bag and tubing will be concealed with opaque covering.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-SARS-CoV-2 equine immunoglobulin F(ab')2 fragments (INOSARS)
Description: INOSARS is a polyvalent passive immunization based on anti-SARS-CoV-2 immunoglobulin F(ab')2 fragments from hyperimmune equine serum. Inactive ingredients: water for injection, sodium chloride and less than 10% of total protein content.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-SARS-CoV-2 equine immunoglobulin F(ab')2 fragments (INOSARS)
Description: INOSARS is a polyvalent passive immunization based on anti-SARS-CoV-2 immunoglobulin F(ab')2 fragments from hyperimmune equine serum. Inactive ingredients: water for injection, sodium chloride and less than 10% of total protein content.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-SARS-CoV-2 equine immunoglobulin F(ab')2 fragments (INOSARS)
Description: INOSARS is a polyvalent passive immunization based on anti-SARS-CoV-2 immunoglobulin F(ab')2 fragments from hyperimmune equine serum. Inactive ingredients: water for injection, sodium chloride and less than 10% of total protein content.
Study: NCT05861622

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moisturizer
Description: The test product is a novel moisturizer, that contains active ingredients, including rambutan extract, niacinamide, and glycoin.
Study: NCT05351918

Intervention type: OTHER
Intervention: acupuncture
Description: Acupuncture points are punctured with needles.

Intervention type: OTHER
Intervention: acupuncture
Description: Acupuncture points are punctured with needles.
Study: NCT06391645

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nerve Growth Factor
Description: intravenously injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nerve Growth Factor
Description: intravenously injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nerve Growth Factor
Description: intravenously injection
Study: NCT05655403

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Step training program
Description: The program will consist of 3 phases: (1) getting familiar, (2) increasing complexity, and (3) consolidating skills. In Phase 1, the participants will be asked to use one foot to step on single-colored stepping panels located in a specific region of the plastic mat (e.g., upper quadrant). In Phase 2, the exercise will progress by introducing the following 4 cognitively challenging stepping tasks. After finishing the 4 stepping tasks in Phase 2, the exercises will progress to Phase 3, which will consolidate the participants' stepping and cognitive skills. The following 4 additional stepping tasks will be introduced. The instructor will tailor the exercises for each participant, based on their training performance.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Step training program
Description: The program will consist of 3 phases: (1) getting familiar, (2) increasing complexity, and (3) consolidating skills. In Phase 1, the participants will be asked to use one foot to step on single-colored stepping panels located in a specific region of the plastic mat (e.g., upper quadrant). In Phase 2, the exercise will progress by introducing the following 4 cognitively challenging stepping tasks. After finishing the 4 stepping tasks in Phase 2, the exercises will progress to Phase 3, which will consolidate the participants' stepping and cognitive skills. The following 4 additional stepping tasks will be introduced. The instructor will tailor the exercises for each participant, based on their training performance.
Study: NCT06166550

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parent's Emotional Intelligence Network
Description: A two-day in-person training session will be arranged for the participating parents at least one week apart. The psychologists will conduct the training session on emotional intelligence. A training of the trainer manual will be developed to train the psychologists. The training session will include a power point presentation and certain group and individual activities to practice emotional intelligence. The participants will also be given a diary and a mobile app in order to practice emotional intelligence at home.
Study: NCT06215495

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: reduced target volume
Description: Delineate residual tumor(GTVp) and tumor bed(GTVtb) on enhanced contrast CT-MRI(T2 fluid attenuated inversion recovery, T2 FLAIR) fusion images. GTVtb and GTVp are expanded by 1cm to CTV_6000.~The clinical target volume_6000 cGy (CTV_6000) is partially reduced beyond the skull and midline. According to the CT-MRI(T2 FLAIR) fusion images, the edema area that cannot be seen on contrast-enhanced CT and only can be seen on MRI should be included.~If CTV_6000 includes thalamus, basal ganglia, brainstem or motor cortex, dose of these areas will be limited no more than 54Gy
Study: NCT06166550

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent's Emotional Intelligence Network
Description: A two-day in-person training session will be arranged for the participating parents at least one week apart. The psychologists will conduct the training session on emotional intelligence. A training of the trainer manual will be developed to train the psychologists. The training session will include a power point presentation and certain group and individual activities to practice emotional intelligence. The participants will also be given a diary and a mobile app in order to practice emotional intelligence at home.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Diary
Description: A diary will be developed that contain different practice materials regarding emotional intelligence. It will be a personal diary given to the participants to take to home.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Diary
Description: A diary will be developed that contain different practice materials regarding emotional intelligence. It will be a personal diary given to the participants to take to home.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mobile App
Description: It will be a mobile app, developed based on the concept of emotional intelligence. It will contain different videos, audios, and texts related to emotional intelligence. It will also provide a communication platform where users can communicate through texts and upload documents.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile App
Description: It will be a mobile app, developed based on the concept of emotional intelligence. It will contain different videos, audios, and texts related to emotional intelligence. It will also provide a communication platform where users can communicate through texts and upload documents.
Study: NCT06110650

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib
Description: Surufatinib 300mg orally, once a day, every 21 days for one cycle, treatment until disease progression or intolerance
Study: NCT06215495

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: EORTC (European organisation for research and treatment of cancer) target volume
Description: delineate according to EORTC guideline
Study: NCT06305897

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRYONOVE (EC14_4osc)
Description: The prototype is a variant version from that of a CE marked MD already commercialized (Cryobeauty mains, Cryobeauty Pharma SAS, France) which produces a cryogenic spray sequence (EC14). The prototype is intended to treat pigmented spots of the face (PIH spots and senile and solar lentigos).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRYONOVE (EC+05_1osc)
Description: The prototype is a variant version from that of a CE marked MD already commercialized (Cryobeauty mains, Cryobeauty Pharma SAS, France) which produces a cryogenic spray sequence (EC05_1osc). The prototype is intended to treat pigmented spots of the face (PIH spots and senile and solar lentigos).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRYONOVE (EC+05_2osc)
Description: The prototype is a variant version from that of a CE marked MD already commercialized (Cryobeauty mains, Cryobeauty Pharma SAS, France) which produces a cryogenic spray sequence (EC05_2osc). The prototype is intended to treat pigmented spots of the face (PIH spots and senile and solar lentigos).
Study: NCT06157749

Intervention type: OTHER
Intervention: Gait analysis
Description: It will be carried out on a 10-meter flat surface, with the participant walking at normal walking speed.
Study: NCT04770766

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre

Intervention type: OTHER
Intervention: Non-medical practitioners
Description: All observational research activity in each cohort is related to the exposure of non-medical practitioners in the Emergency Department or Urgent Treatment Centre
Study: NCT04881903

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Intervention for Suicidal Thoughts (MIST)
Description: This is an interpretation bias modification intervention that is designed to target cognitive factors that contribute to suicide risk. Participants will be instructed to complete at least 5 treatment sessions per week for a period of 4 weeks. Each session takes approximately 10 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Intervention for Reducing Anger (MIRA)
Description: This is an interpretation bias modification intervention that is designed to target hostile interpretation bias. Participants will be instructed to complete at least 5 treatment sessions per week for a period of 4 weeks. Each session takes approximately 10 minutes.
Study: NCT05851937

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Written language intervention
Description: Young adults with Intellectual and Developmental Disabilities (IDD) are taught reading comprehension strategies in three phases (before, during, after) using a graphic organizer as visual support. At the beginning of each phase, the interventionist: (a) defines the strategies, (b) describes and models how to use the strategies, and (c) answers questions about the strategies. Then the participant practices the strategies during 45-min sessions, two times per week, over 3 months. Each session follows the teach-model-coach-review format, the interventionist: (a) reviews the strategies (5 min), (b) models the strategies using a think-aloud (10 min), (c) prompts the participant to practice the strategies with support (15 min), (d) prompts the participant to use a think-aloud to practice the strategies independently using a functional literacy text (10 min), and (e) reviews and summarizes the session (review; 5 min).
Study: NCT04877080

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Fast Dual CAR-T Injection
Description: Fast Dual CAR-T injection is a autologous dual CAR-T targeted CD19 and BCMA. A single infusion of CART cells will be administered intravenously.
Study: NCT05311501

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-surgical periodontal treatment
Description: Non-Surgical periodontal Treatment was performed by removing supra and subgingival calculus and using both ultrasonic and manual instruments. Oral Hygiene Instructions (OHI) were provided throughout the experimental period. Local anesthesia was performed only when needed.
Study: NCT05084066

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Repeated remote ischemic preconditioning
Description: An automated device performs four 5-minute episodes of upper limb ischemia in which the cuff pressure in the experimental group remains at 200 mmHg for 5 minutes, causing and ensuring ischemia. Ischemic episodes alternate with 5-minute reperfusion. The intervention lasts a total of 35 minutes. The participant places the device on his upper arm and presses the Start button, starting the intervention. The intervention takes place at rest in the patient's home environment daily for 28 days. During the first visit to the research center, the research assistant teaches the participant how to use the device. The device measures the patient's blood pressure at the start of the intervention. If the patient's blood pressure is above 200 mmHg, the device will not perform the intervention.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Simulation of repeated remote ischemic preconditioning (sham)
Description: The automated device simulates the intervention of the experimental group with the difference that the device does not apply pressure to the upper limb and, therefore, no ischemia occurs.
Study: NCT04851184

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gaze stabilization Exercises using Virtual Reality Device
Description: Participants will utilize a wireless virtual reality headset to perform their gaze stabilization exercises to better control the background and visual field as well as collect data related to speed, excursion, and duration of head movements.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gaze stabilization non-instrumented
Description: Participants will perform gaze stabilization exercises in a non-instrumented manner. Subjects are instructed to focus on a letter on a piece of paper held at arm's length. They are instructed to move their head back and forth as quickly as they can while keeping the letter in focus. The total duration of the exercise (from 10 - 240 seconds) and background complexity (simple to complex moving) are increased gradually according to patient symptoms.
Study: NCT05389488

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OsciPulse system
Description: The OsciPulse system is a pneumatic compression system designed to provide intermittent compression to the limbs to augment venous blood flow.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Flowtron ACS900
Description: The Arjo Flowtron ACS900 intermittent pneumatic compression system provides compression the calf to augment venous blood flow.
Study: NCT05265767

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Auto CD34+PBSC transduced with a lentiviral vector encoding a novel coagulation factor VIII transgene
Description: Auto CD34+PBSC transduced with a lentiviral vector encoding a novel coagulation factor VIII transgene administered by IV infusion following conditioning regimen.
Study: NCT05383001

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: combination regimen tremelimumab /durvalumab
Description: Induction treatment: 2 cyles of Q3W second-line plantium-based chemotherapy according to standard of care: Cisplatin or carboplatin in combination with pemetrexed, paclitaxel, nab-paclitaxel, vinorelbine or gemcitabine~Combination treatment:~Durvalumab 1500 mg fixed dose plus tremelimumab 300 mg fixed bolus dose~Maintenance Therapy:~Durvalumab 1500 mg fixed dose Q4W up to 12 cycles within the study

Intervention type: DRUG
Group type: OTHER
Intervention: platinum-based chemotherapy (SoC)
Description: Induction treatment: 2 cyles of Q3W second-line plantium-based chemotherapy according to standard of care: Cisplatin or carboplatin in combination with pemetrexed, paclitaxel, nab-paclitaxel, vinorelbine or gemcitabine~Combination treatment:~Continuation of second-line chemotherapy with 2-4 further cycles (Q3W) platinum-based combination therapy.~Maintenance Therapy:~Optional continued maintenance therapy with pemetrexed according to marketing authorization will be allowed for a maximum of 13 cycles.
Study: NCT05946304

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: moderate-intensity continuous exercise training (MICT) group
Description: Exercise session: Warm-up: 60-70% peak heart rate (HR) - 10min; Training: 70-85% peak HR - 35min; Cool-down: 60-70% peak HR - 15min.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: high-intensity interval training (HIIT) group
Description: Warm-up: 60-70% peak heart rate (HR) - 10min; Training: 85-95% peak HR - 25 minutes (4x4-minutes of high-intensity intervals interspersed with 3 minutes of low-intensity intervals); Cool-down: 60-70% peak HR - 10min.