TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04463498

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group-based cognitive behavioral therapy for insomnia
Description: Sleep education, sleep restriction, stimulus control, cognitive restructuring, relaxation techniques

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group-based cognitive behavioral therapy for insomnia
Description: Sleep education, sleep restriction, stimulus control, cognitive restructuring, relaxation techniques

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group-based cognitive behavioral therapy for insomnia and additive bb-glasses
Description: Sleep education, sleep restriction, stimulus control, cognitive restructuring, relaxation techniques, bb-glasses worn from 3 hrs before bedtime.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 8-week wait list for sleep-school
Description: Treatment as usual in a psychiatric outpatient clinic
Study: NCT05617742

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI-46
Description: 68Ga-FAPI-46 is a radioactive diagnostic agent for PET imaging in the detection of Fibroblast Activation Protein (FAP) positive tumor cells in cancer patients
Study: NCT06003517

Intervention type: PROCEDURE
Intervention: Screening with PSI check list
Description: Screening PSI with institutional check list

Intervention type: PROCEDURE
Intervention: Screening with PSI check list
Description: Screening PSI with institutional check list
Study: NCT06554743

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Default Veg
Description: Received a plant-based meal as the default option on the event RSVP form that required participants to pre-select their meal choice

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Default Meat
Description: Received a meal with meat as the default option on the event RSVP form that required participants to pre-select their meal choice
Study: NCT06215092

Intervention type: OTHER
Intervention: Psychological assessment
Description: Psychological assessment of cognitive and social-emotional functioning.

Intervention type: OTHER
Intervention: Psychological assessment
Description: Psychological assessment of cognitive and social-emotional functioning.

Intervention type: OTHER
Intervention: Psychological assessment
Description: Psychological assessment of cognitive and social-emotional functioning.

Intervention type: OTHER
Intervention: Psychological assessment
Description: Psychological assessment of cognitive and social-emotional functioning.

Intervention type: OTHER
Intervention: Psychological assessment
Description: Psychological assessment of cognitive and social-emotional functioning.

Intervention type: OTHER
Intervention: Psychological assessment
Description: Psychological assessment of cognitive and social-emotional functioning.
Study: NCT06246305

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional physical therapy training
Description: conventional therapy rehabilitation program is divided into three phases: on-brace, off-brace, and active mobilization. The on-brace phase (post-op 0-6 weeks) mainly consists of low-intensity whole-body exercises with shoulder girdle, elbow, and hand mobilization exercises on the affected side. The off-brace phase (post-op 6-9 weeks) consists of passive shoulder ROM exercises using an exercise stick and an early scapular stabilization exercise. The active mobilization phase (post-op 9-12 weeks) consists of both active and passive shoulder ROM , strengthening exercise with progressive resistance, and scapular stabilization exercises. The intervention is done 3 times per week for 12 weeks.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality (VR) training
Description: During the on-brace phase (0-6 weeks), participants in this group will use the program as performed in the control group. During the off-brace (6-9 weeks post-op) and active mobilization phases (9-12 weeks post-op), participants will use the Virtual Reality machine. this program involves warming up and down stretching exercises and exercise training that includes bilateral shoulder elevation, boxing, bowling and tennis games accompanied by avatar. The intervention is done 3 times per week for 12 weeks.
Study: NCT05202912

Intervention type: DRUG
Group type: OTHER
Intervention: IDX-1197(After a meal)
Description: randomized, open-label, single-dose, 2-period, 2-sequence crossover study in healthy male Korean and Caucasian volunteers

Intervention type: DRUG
Group type: OTHER
Intervention: IDX-1197(fasting)
Description: open-label, single-dose study in Chinese male volunteers
Study: NCT06233500

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pars plana vitrectomy
Description: All eyes in this study will be subjected to pars plana vitrectomy procedure with these main steps:~* 23 G trocar system will be used~* Posterior vitreous detachment will be induced with the aid of triamcinolone acetate injection, and core vitrectomy will be done~* Brilliant blue stain will be injected, and ILM forceps will be used for ILM peeling~Patients will be divided then into two groups:~Group A: Only wide ILM peeling up to the arcades well be done Group B: ILM peeling with flap well be done~* Shaving of the vitreous base, and then fluid air exchange~* SF 6 gas tamponade will be used
Study: NCT04760769

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tavapadon
Description: Participants will receive Tavapadon at a dose of (5 to 15) mg QD, orally during a 58-week treatment period.
Study: NCT04548973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: Esketamine

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: 2ml normal saline
Study: NCT06400498

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prompted Palliative Care Consult
Description: When a patient is randomized to the Palliative Care Consultation Prompt Group, a clinical decision support tool in the electronic health record will inform the treating clinician of the patient's serious illness and the results of the Surprise Question and prompt the treating clinician to consider a palliative care consultation. If the treating clinician feels a palliative care consultation would be indicated for the patient, the clinical decision support tool will facilitate the placement of a palliative care consultation by the treating clinician. If the treating clinician feels that a palliative care consultation would not be indicated, then the clinical decision support will record a reason it is not indicated.
Study: NCT06061042

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early time restricted eating
Description: Subjects will follow an isocaloric diet, designed by a dietician. The eating window for the early-TRE group is between 7 AM - 5 PM

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Late time restricted eating
Description: Subjects will follow an isocaloric diet, designed by a dietician. The eating window for the late-TRE group is between 10 AM - 8 PM
Study: NCT04301648

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STAR Nurse
Description: This intervention will consist in that the nurse who is in the hemodynamic nurse's office will do the STAR Nurse's tasks and competences.~Although the intervention will be detailed through phase 1 (integrative review) and 2 (Delphy methodology).~It is expected that the main STAR nurse's competencies and tasks in the nurse's office will be:~1. To guarantee a comprehensive evaluation and appropriate triage to candidates for an interventional procedure of structural heart disease, coordinating the request for complementary tests and previous visits.~2. Make education to the patient and family.~3. Make communication bridge with cardiologists.~4. Establish specific patient-centered care processes.~5. Promote continuity of care after discharge, follow up after discharge, and reevaluate quality of life and fragility.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Common Practice
Description: Common practice will consist in that the nurse who is in the hemodynamic nurse's office will do her usual task that is exclusively health education.
Study: NCT06155357

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multicomponent lifestyle intervention program
Description: The multicomponent lifestyle intervention program is targeted at risk factor management, increased exercise capacity, and weight loss. The program will commence upon order/referral for ablation. Ablation would occur during the lifestyle program and the program will be continued after the ablation to complete 12 weeks or up to 36 exercise sessions.
Study: NCT05291754

Intervention type: DEVICE
Group type: OTHER
Intervention: PEEK Cranioplasty
Description: 3D printed PEEK skull implant
Study: NCT04994223

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 10 MG Oral Tablet [Xarelto]
Description: rivaroxaban has shown improved results after revascularization for PAD in terms of limb survival

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rivaroxaban 10 MG Oral Tablet [Xarelto]
Description: rivaroxaban has shown improved results after revascularization for PAD in terms of limb survival
Study: NCT05477654

Intervention type: DIAGNOSTIC_TEST
Intervention: Extensive motor-cognitive testing protocol
Description: Screening of their functional performance while monitoring brain and muscle activity

Intervention type: DIAGNOSTIC_TEST
Intervention: Extensive motor-cognitive testing protocol
Description: Screening of their functional performance while monitoring brain and muscle activity
Study: NCT05124977

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antimicrobial Stewardship
Description: Antimicrobial stewardship based on daily clinical assessment of clinical cure. Discontinuation of appropriate antibiotic therapy antibiotics if criteria of clinical cure of confirmed pneumonia are met. Intensivists will perform clinical assessment daily in order to decide on the pursuit or discontinuation of antibiotic therapy.
Study: NCT06233617

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% Sodium Chloride Injection
Description: biliteral administration of 20ml of 0,2% ropivacaine + 2ml 0.9% sodium chloride for the erector spine plane block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone 4 Mg/mL Injectable Solution
Description: biliteral administration of 20ml of 0,2% ropivacaine with 4mg Dexamethasone for the erector spine plane block

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine injection
Description: biliteral administration of 20ml of 0,2% ropivacaine with 50ug Dexmedetomidine for the erector spine plane block
Study: NCT06506149

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microwave ablation(MWA) device
Description: The device for USG-guided MWA treatment would be performed under USG guidance, aiming to ablate the entire thyroid gland, i.e. the right lobe, left lobe, isthmus and pyramidal lobe.
Study: NCT04838483

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Indirect adhesive restoration of posterior teeth
Description: Indirect restoration of significant loss of dental hard tissue
Study: NCT06099197

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brain CareNotes
Description: The Brain CareNotes mobile telehealth app is used by unpaid caregivers for BPSD management. It includes remote communication with an external human support person-a care coach-as well as features for users to independently perform health-related activities.
Study: NCT06121648

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hydrotherapy
Description: 30 degrees temperature pool balance and breathing therapy

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: neurological physiotherapy
Description: Balance and neurological physiotherapy on land
Study: NCT06262438

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quizartinib
Description: Quizartinib is a novel oral Class III receptor tyrosine kinase (RTK) inhibitor exhibiting highly potent and selective but reversible inhibition of FMS-like tyrosine kinase FLT3. The dose will be adjusted for the patient's body weight (BW) as measured at the start of each course. Quizartinib will be administered orally once daily and is taken for 14 consecutive days during induction and consolidation courses.~Induction course 1: Start on day 13; Induction course 2: Start on day 9; Consolidation course 1: Start on day 6; Consolidation courses 2 and 3 (only if no allo-SCT is done): Start on day 6.~Continuation courses 1-6: patients will receive quizartinib for six 28-day courses. For the first 15 days of course 1 a starting dose will be applicable. On course 1 Day 16, the dose will be increased if the average QTc of the triplicate Electrocardiograms is ≤450 msec on course 1 Day 15. Once the dose is increased, the patient may continue on this dose as long as dose reduction is not needed.
Study: NCT06099197

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dementia Guide Expert
Description: Dementia Guide Expert provides education only and no interactive BPSD management support, coaching, assessment, or external response. It contains evidence-based expert information on what dementia is, types, contributing factors, risks, symptoms, stages, diagnosis, tests, treatment, management, communication techniques, and links to resources and support services.
Study: NCT06135584

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pioglitazone metformin tablets
Description: Drug intervention for 24 weeks and follow-up for another 72 weeks (fasting blood glucose was controlled below 7.0mmol/l throughout the study)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Other drugs
Description: Chinese patent medicine or hypoglycemic drugs other than pioglitazone metformin tablets, pioglitazone, metformin, GLP1

Intervention type: OTHER
Group type: OTHER
Intervention: Drug-free
Description: Drug-free
Study: NCT05124977

Intervention type: DRUG
Group type: OTHER
Intervention: Standard management
Description: Standard management: duration of appropriate antibiotic for confirmed pneumonia fixed for 7 days according to guidelines. In the control group, intensivists will perform clinical assessment daily, but the antibiotic will not be discontinued until 7 days whatever the clinical cure.
Study: NCT05386121

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided Erector Spinae Plane Block
Description: Using a 22-gauge 80 mm echogenic needle under ultrasound guidance, 0.5 mL/kg of bupivacaine 0.125% will be injected in the fascial plane deep to erector spinae muscle after conﬁrming correct needle location by a negative aspiration test then by injecting 0.5-1 ml saline and observing the ﬂuid lifting the erector spinae muscle off the transverse process (hydrodissection). The ultrasound probe will be placed 2-3 cm lateral to the spinous process on a parasagittal plane, to visualize the erector spinae muscle and transverse process, directing the needle craniocaudally using the in-plane technique. The spread of the injectate will be observed to distribute within this plane.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided Quadratus Lumborum Block
Description: Using a 22-gauge 80 mm echogenic needle under ultrasound guidance, 0.5 mL/kg of bupivacaine 0.125% will be injected in the fascial plane between the quadratus lumborum and psoas major muscle after conﬁrming correct needle location by a negative aspiration test then by injecting 0.5-1 ml saline (hydrodissection). The ultrasound probe will be placed 2-3 cm lateral to the L2 spinous process on an axial plane, to visualize the transverse process with psoas major muscle anterior, quadratus lumborum muscle lateral and erector spinae muscle posterior to it. The needle is inserted from the medial side of the probe and advanced laterally using the in-plane technique. The spread of the injectate will be observed to distribute within the target plane.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound Machine
Description: Sonosite S-Nerve (USA) with a linear multi-frequency 6-13 MHz (hockey stick) transducer
Study: NCT05016089

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The 16-style simplified Pilates exercise programme
Description: The 16-style simplified Pilates exercise programme was developed by a group of experienced Pilates and rehabilitation experts from our completed pilot work.

Intervention type: OTHER
Group type: OTHER
Intervention: The 16-style simplified Pilates exercise programme
Description: The 16-style simplified Pilates exercise programme was developed by a group of experienced Pilates and rehabilitation experts from our completed pilot work.
Study: NCT05545748

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Zero (0) Tolerance Program (SToP)
Description: 1. Urine Cotinine Feedback: Explaining what the cotinine-sensitive dipstick test kit score mean. Cotinine-sensitive dipstick test kit is a simple, cost-effective test to determine smoking status. It is an easy-to-read test strip that can be used with either a saliva or a urine sample.~2. Giving reminder objects (Magnet, sticker): For example; at the entrance door of the house: 0 TOLERANCE magnet to cigarettes; No smoking in my home label.~3. Informative materials (information notes and brochures): Brochures on the harms of second-hand smoking (SHS) and third-hand smoking (THS), the diseases they cause, and how to protect them~4. Informative telephone text messages: Reminder phone messages related to SHS and THS

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exposure Feedback Group
Description: 1. Urine Cotinine Feedback: Explaining what the cotinine-sensitive dipstick test kit score mean. Cotinine-sensitive dipstick test kit is a simple, cost-effective test to determine smoking status. It is an easy-to-read test strip that can be used with either a saliva or a urine sample.
Study: NCT04418895

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chemoradiation
Description: Subjects will receive neoadjuvant chemoradiation per standard of care. This is typically comprised of radiotherapy of 5040 cGy (centigray) with concurrent capecitabine 825 mg/m2 by mouth (po) two times daily (bid) (typically rounded to the nearest 500 mg dose) or infusional 5-fluorouracil (5FU). However, dosing and administration are at the discretion of the treating medical and radiation oncologist.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: short course radiation therapy
Description: An acceptable alternative approach is short-course radiation therapy per standard of care, which is typically comprised of radiotherapy of 25 Gy (gray) in 5 fractions, with surgery within 1 week of completion of therapy or delayed for 6-8 weeks. Selection of the optimal radiation therapy approach is at the discretion of the treating medical oncologist, radiation oncologist, and surgical oncologist. However, generally, short-course radiation therapy is not recommended for low-lying tumors less than 5 centimeters (cm) from the anal verge.
Study: NCT05386121

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound Machine
Description: Sonosite S-Nerve (USA) with a linear multi-frequency 6-13 MHz (hockey stick) transducer
Study: NCT04418895

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mFOLFOX6
Description: possible consolidative neo-adjuvant chemotherapy. This treatment is at the discretion of the treating medical oncologist, radiation oncologist, and surgical oncologist.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAPOX
Description: possible consolidative neo-adjuvant chemotherapy. This treatment is at the discretion of the treating medical oncologist, radiation oncologist, and surgical oncologist.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fluoropyrimidine +/- oxaliplatin
Description: possible adjuvant chemotherapy regimen. Subjects who do not receive preoperative mFOLFOX6 or CAPOX typically receive postoperative adjuvant chemotherapy with a fluoropyrimidine +/- oxaliplatin for an additional 16-18 weeks of therapy, if permitted based on recovery after surgical resection and post-surgical performance status. This treatment is at the discretion of the treating medical oncologist. Subjects will remain on study regardless of postoperative therapy administration or duration.
Study: NCT05386121

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Echogenic needle
Description: A 22-gauge 80 mm needle the sonoplex needle manufactured by PAJUNK (USA)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Echogenic needle
Description: A 22-gauge 80 mm needle the sonoplex needle manufactured by PAJUNK (USA)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: Given intravenously (1 µg/kg) as part of induction of general anesthesia (GA) added to propofol 2 mg/kg and atracurium 0.5 mg/kg Intraoperatively, intravenous fentanyl 0.5 µg/kg (with a maximum dose of 2 µg/kg) will be administered in response to any increase in hemodynamics by more than 20% of baseline values in response to skin incision or there after throughout surgery (after exclusion of other causes of hemodynamic changes)
Study: NCT05609357

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Head-up Cardiopulmonary Resuscitation
Description: Elevate patient's head to 30 degrees by EleGARD System during cardiopulmonary resuscitation
Study: NCT04716894

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 474121
Description: BI 474121 oral solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Itraconazole oral solution
Study: NCT05309642

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Intermittent calorie restriction
Description: Recipes will be provided with suggestions of meals that would not exceed the calorie restriction. For the remaining 5 days of the week, they will receive instructions and recipes that follows the Korean Dietary Reference Intakes (KDRIs), with an intake limit of 2,000 kcal/day for women and 2,500 kcal/day for men. The percentage of energy (E%) from different macronutrients in the recipes will be 45-60 E% carbohydrates, 25 E% fat and 10-20 E% protein.
Study: NCT05490758

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sensorimotor training
Description: sensorimotor training include activities like play with dough, peg games, puzzles for 5 days a week for 4 week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: constraint induced movement therapy
Description: constraint induced movement therapy in which arm was constraint for 6 hours a day for 5 days a week for 4 week.
Study: NCT05922605

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-ketamine & Ropivacaine
Description: The experiment group (Group E) will receive a mixture of ropivacaine 0.2% 0.7 ml／kg and preservative-free S-ketamine 0.5 mg/kg caudally for postoperative analgesia.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine
Description: The experiment group (Group C) will receive ropivacaine 0.2% 0.7 ml／kg plain and equial volume saline caudally for postoperative analgesia.