Study: NCT06679998

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single dose, AAPB by injection, intravenous drip.
Description: Subjects received a single intravenous infusion of AAPB for injection. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, and each time was continuously injected for 60 min±5min.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single dose, AAPB by injection, intravenous drip.
Description: Subjects received a single intravenous infusion of AAPB for injection. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, and each time was continuously injected for 60 min±5min.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single dose, AAPB by injection, intravenous drip.
Description: Subjects received a single intravenous infusion of AAPB for injection. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, and each time was continuously injected for 60 min±5min.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single dose, AAPB by injection, intravenous drip.
Description: Subjects received a single intravenous infusion of AAPB for injection. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, and each time was continuously injected for 60 min±5min.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single dose, AAPB by injection, intravenous drip.
Description: Subjects received a single intravenous infusion of AAPB for injection. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, and each time was continuously injected for 60 min±5min.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Single dose, placebo, intravenous drip.
Description: Subjects received a single intravenous infusion of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Single dose, placebo, intravenous drip.
Description: Subjects received a single intravenous infusion of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Single dose, placebo, intravenous drip.
Description: Subjects received a single intravenous infusion of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Single dose, placebo, intravenous drip.
Description: Subjects received a single intravenous infusion of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Single dose, placebo, intravenous drip.
Description: Subjects received a single intravenous infusion of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Multiple dosing, AAPB for injection, intravenous drip
Description: Subjects received AAPB for injection with multiple intravenous drips. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, 60 min±5min each time, for 7 consecutive days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Multiple dosing, AAPB for injection, intravenous drip
Description: Subjects received AAPB for injection with multiple intravenous drips. Each dose of AAPB for injection was dissolved with 0.9% sodium chloride injection, the infusion volume was 100mL, once a day, 60 min±5min each time, for 7 consecutive days.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Multiple dosing, placebo, IV drip
Description: Subjects received multiple intravenous doses of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time for 7 consecutive days.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Multiple dosing, placebo, IV drip
Description: Subjects received multiple intravenous doses of placebo. Each dose of placebo was dissolved by 0.9% sodium chloride injection with an infusion volume of 100mL once a day for 60 min±5min each time for 7 consecutive days.