TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05124301

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Perceptual learning
Description: Reaching task with visual feedback offset from target finger position.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Reaching task with unmanipulated feedback.
Study: NCT06064682

Intervention type: OTHER
Intervention: standard of care biopsy
Description: Image-guided or surgical biopsy or excision of the lesion that is suspected to be recurrent or metastatic osteosarcoma (Group 2).
Study: NCT05909696

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rocuronium
Description: Advanced intravenous injection of rocuronium before the succinylcholine injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rocuronium
Description: Advanced intravenous injection of rocuronium before the succinylcholine injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rocuronium
Description: Advanced intravenous injection of rocuronium before the succinylcholine injection
Study: NCT04726267

Intervention type: DEVICE
Group type: OTHER
Intervention: Wide-field optical coherence tomography
Description: Merged 4 images of wide-field optical coherence tomography, 2 images of vertical scan and 2 images of horizontal scan.
Study: NCT05786261

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: experimental group MIRT
Description: Task 1a: Assessing the effect of MIRT on cortical plasticity tested with rPAS Task 1b: Assessing the effect of MIRT on structural cortical plasticity and brain connectivity tested with MRI Task 1c: Assessing the effect of MIRT on movement-related beta modulation Task 1d: Assessing the effects of MIRT on motor skills formation with reaching tasks Task 1e: Assessing the effects of MIRT on EEG correlates of motor skills formation Task 2a: Assessing the effect of MIRT on muscle synergies during gait Task 2b: Assessing the effect of MIRT on muscle synergies during reaching movements Task 3a: Assessing the effect of MIRT on sleep microstructure

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EEG task rTMS, fMRI
Description: EEG task rTMS, fMRI

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EEG task rTMS, fMRI
Description: EEG task rTMS, fMRI
Study: NCT06513221

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy, Bevacizumab, Adebrelimab
Description: Adebrelimab: 1200mg，q3w Bevacizumab: 7.5mg/kg，q3w Fruquintinib: 4mg po d1\~d14, q3w Chemotherapy: XELOX/mXELIRI: conventional dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy, Bevacizumab, Adebrelimab
Description: Adebrelimab: 1200mg，q3w Bevacizumab: 7.5mg/kg，q3w Fruquintinib: 4mg po d1\~d14, q3w Chemotherapy: XELOX/mXELIRI: conventional dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy, Bevacizumab, Adebrelimab
Description: Adebrelimab: 1200mg，q3w Bevacizumab: 7.5mg/kg，q3w Fruquintinib: 4mg po d1\~d14, q3w Chemotherapy: XELOX/mXELIRI: conventional dose
Study: NCT06480929

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Contrast TTE procedure, the SonoVue ultrasound agent
Description: The intervention involved using contrast-enhanced transthoracic echocardiography (TTE) to improve the detection of left ventricular thrombus in patients with anterior ST-elevation myocardial infarction (STEMI).
Study: NCT05553379

Intervention type: DIAGNOSTIC_TEST
Intervention: FeNO measurement
Description: FeNO measurement at each visit

Intervention type: DIAGNOSTIC_TEST
Intervention: FeNO measurement
Description: FeNO measurement at each visit
Study: NCT05506332

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax and 6-mercaptopurine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6-mercaptopurine
Description: Venetoclax and 6-mercaptopurine
Study: NCT05441150

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Low dose ketamine infusion
Description: Administering low-dose ketamine infusion to the patient under general anesthesia for Ketamine Group.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: 0.9% NaCl infusion
Description: Same dose of 0.9% NaCl infusion as the dose of ketamine for Control Group.
Study: NCT04710940

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes BOOST
Description: Participants will receive supportive care using technology for DSMT in addition to usual care.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants will receive usual care for DSMT.
Study: NCT05702905

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: physical exercise
Description: All subjects after randomization will be reviewed and evaluated by a trainer, and then will receive guidance of physical exercise.The trainer will formulate an exercise plan for each subject. The exercise plan consists of 30 minutes of moderate and low intensity continuous aerobic exercise every day, with a frequency of 5-7 days/week. The form of exercise can be determined according to personal hobbies, such as fast walking, jogging, climbing, swimming, etc. The exercise diary will be distributed to each subject, and the subjects are required to make a return visit once every four weeks, return the exercise diary each time, and the trainer will provide guidance to the subjects according to their compliance.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: physical exercise
Description: All subjects after randomization will be reviewed and evaluated by a trainer, and then will receive guidance of physical exercise.The trainer will formulate an exercise plan for each subject. The exercise plan consists of 30 minutes of moderate and low intensity continuous aerobic exercise every day, with a frequency of 5-7 days/week. The form of exercise can be determined according to personal hobbies, such as fast walking, jogging, climbing, swimming, etc. The exercise diary will be distributed to each subject, and the subjects are required to make a return visit once every four weeks, return the exercise diary each time, and the trainer will provide guidance to the subjects according to their compliance.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: physical exercise
Description: All subjects after randomization will be reviewed and evaluated by a trainer, and then will receive guidance of physical exercise.The trainer will formulate an exercise plan for each subject. The exercise plan consists of 30 minutes of moderate and low intensity continuous aerobic exercise every day, with a frequency of 5-7 days/week. The form of exercise can be determined according to personal hobbies, such as fast walking, jogging, climbing, swimming, etc. The exercise diary will be distributed to each subject, and the subjects are required to make a return visit once every four weeks, return the exercise diary each time, and the trainer will provide guidance to the subjects according to their compliance.
Study: NCT04878172

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure Firm
Description: The TempSure firm will be used on the abdomen for non-invasive lipolysis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure Firm
Description: The TempSure firm will be used on the abdomen for non-invasive lipolysis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure Firm
Description: The TempSure firm will be used on the abdomen for non-invasive lipolysis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure Firm
Description: The TempSure firm will be used on the abdomen for non-invasive lipolysis.
Study: NCT04928989

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: convergence dialogue meeting
Description: Digital counceling with convergence dialogue tripartite meeting. will be conducted in accordance with work dialogue for return to work. Workplace dialogue among employee with neck problems, an expert in the work environment, and the immediate manager. The purpose of the conversations is, in open dialogue, to reach a common understanding of the situation and identify possible interventions to maintain or improve the employee´s work ability.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: convergence dialogue meeting
Description: Digital counceling with convergence dialogue tripartite meeting. will be conducted in accordance with work dialogue for return to work. Workplace dialogue among employee with neck problems, an expert in the work environment, and the immediate manager. The purpose of the conversations is, in open dialogue, to reach a common understanding of the situation and identify possible interventions to maintain or improve the employee´s work ability.
Study: NCT05103774

Intervention type: DIAGNOSTIC_TEST
Intervention: T3-T4-TSH
Description: thyroid function tests

Intervention type: DIAGNOSTIC_TEST
Intervention: T3-T4-TSH
Description: thyroid function tests
Study: NCT04644575

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: efanesoctocog alfa (BIVV001)
Description: Pharmaceutical form:Solution for Injection Route of administration: Intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: efanesoctocog alfa (BIVV001)
Description: Pharmaceutical form:Solution for Injection Route of administration: Intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: efanesoctocog alfa (BIVV001)
Description: Pharmaceutical form:Solution for Injection Route of administration: Intravenous
Study: NCT06664515

Intervention type: PROCEDURE
Intervention: Ciro Costagliola
Description: invert flap tecnique
Study: NCT05930249

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized multidomain intervention
Description: 1. Patients will complete personalized cognitive training based on baseline fNIRS on APP (20-30 mins/day, 3-4 days/week, 6 months).~2. Shared decision-making on risk factor of stroke between doctors and patients~3. Social support by grouping patients online to ensure close interaction with other patients in the same arm
Study: NCT06341569

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Respiratory breathing techniques group
Description: Target group: subjects in the respiratory breathing techniques group. Program duration: the program lasts for 14 weeks.~Breathing techniques: the program includes various breathing exercises, including:~Diaphragmatic breathing teaches participants to breathe deeply, engaging the diaphragm muscle, which can improve lung capacity and relaxation.~Pursed-lips breathing: this technique involves inhaling through the nose and exhaling slowly through pursed lips, which can help slow down breathing and manage shortness of breath.~Alternate nostril breathing: this technique involves closing one nostril while inhaling and exhaling through the other nostril alternately.~Relaxation techniques: the program incorporates progressive muscle relaxation techniques. This involves progressively tensing and relaxing different muscle groups.~Medical education: topics like the anatomy of the respiratory system, the importance of proper breathing, potential benefits of specific breathing exercises.
Study: NCT06671509

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YZJ-1139
Description: Single oral dose, 20 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YZJ-1139
Description: Single oral dose, 20 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YZJ-1139
Description: Single oral dose, 20 mg tablet
Study: NCT06673082

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral zinc supplementation
Description: Oral Zinc will be supplemented to the interventional group on a dose of 30 mg elemental zinc/day.
Study: NCT02069288

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludrocortisone
Description: 50 µg of fludrocortisone per os

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 tablet of placebo per os
Study: NCT05346432

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: PS23
Description: PS23 belongs to Lactobacillus paracasei group.Probiotic capsules contain 10 billion CFU (colony forming units) of PS23

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: PS23
Description: PS23 belongs to Lactobacillus paracasei group.Probiotic capsules contain 10 billion CFU (colony forming units) of PS23

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: PS23
Description: PS23 belongs to Lactobacillus paracasei group.Probiotic capsules contain 10 billion CFU (colony forming units) of PS23
Study: NCT05592834

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: positive deviance hearth strategy
Description: The PD-program is run for 3-months with 2 weeks (12 days) of nutrition education and rehabilitation sessions (NERS) conducted in each month. Each day session includes an half hour education session and a one and half hour peer led cooking session. Caretakers learn how to rehabilitate their malnourished children under the supervision and the support of caregivers who have well-nourished children (positive deviants). Children are nutritionally assessed by trained nutrition assistants or clinician on the 1st day of the NERS sessions and after three months.~During the rehabilitation sessions, caregivers learn how to prepare nutrient-rich meals for their children from locally available food identified during the positive deviance-inquiry, and actively practice good feeding and hygiene practices. Caregivers together prepare food menus based on the PD-inquiry good foods or what they can conveniently access but of equal nutritional value.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: positive deviance hearth strategy
Description: The PD-program is run for 3-months with 2 weeks (12 days) of nutrition education and rehabilitation sessions (NERS) conducted in each month. Each day session includes an half hour education session and a one and half hour peer led cooking session. Caretakers learn how to rehabilitate their malnourished children under the supervision and the support of caregivers who have well-nourished children (positive deviants). Children are nutritionally assessed by trained nutrition assistants or clinician on the 1st day of the NERS sessions and after three months.~During the rehabilitation sessions, caregivers learn how to prepare nutrient-rich meals for their children from locally available food identified during the positive deviance-inquiry, and actively practice good feeding and hygiene practices. Caregivers together prepare food menus based on the PD-inquiry good foods or what they can conveniently access but of equal nutritional value.
Study: NCT05389813

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxycodone 20 Mg Oral Tablet
Description: Oxycodone is a semi-synthetic, morphine-like opioid alkaloid with analgesic activity. Oxycodone exerts its analgesic activity by binding to the mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opioids. Binding of the opiate receptor stimulates the exchange of GTP for GDP on the G-protein complex and inhibits adenylate cyclase, thereby preventing cAMP production. Subsequently, the release of nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, and noradrenaline, is inhibited. Oxycodone also inhibits the release of vasopressin, somatostatin, insulin, and glucagon. In addition, oxycodone closes N-type voltage-gated calcium channels and opens G-protein-coupled inwardly rectifying potassium channels resulting in hyperpolarization and reduction of neuronal excitability.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pregabalin 150mg
Description: Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective in its binding to the α2δ VDCC subunit. Despite the fact that pregabalin is a GABA analogue. r synthesizing GABA, and hence may have some indirect GABAergic effects by increasing GABA levels in the brain. In accordance, inhibition of α2δ-1-containing VDCCs by pregabalin appears to be responsible for its anticonvulsant, analgesic, and anxiolytic effects.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Multivitamin with Minerals
Description: Vit A 3000 IU, Vit B1 2.5mg, Vit B2 2.0mg, Vit B12 10mcg, Vit C 150mg, Vit D3 400 IU, Vit E10 IU, Biotin 25mcg, Nicotimamide 30mg, Calcium Pantothenate 3mg, Folic acid 800mcg, Iron Fumarate 18mg, Calcium 125mg, Magnesium Oxide 10mg, Iodine Potassium 150mcg, Manganese sulfate 0.5mg, Phosphorus 23.8mg, Copper sulfate 1.0mg, Molybdinium Sodium 0.10mg, Zinc Sulfate 5.0mg.
Study: NCT06673082

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral
Study: NCT06673225

Intervention type: OTHER
Intervention: Analysis of results
Description: Analysis of previous imaging and/or laboratory tests, vital signs, body composition, pulmonary function, peripheral muscle strength, calf circumference, nutritional risk, quality of life, frailty level, and anxiety and depression. Screening for respiratory diseases, including chronic obstructive pulmonary disease (COPD), lung cancer, tuberculosis, and other lung lesions, is based on spirometry and thoracic radiological images after the health professional's examination. After the multiprofessional procedures, patients will be evaluated by a physician to start specific treatment and/or perform complementary exams if necessary. Every year, they will be re-evaluated to record acute exacerbations of chronic respiratory diseases and assess disease progression through spirometry and thoracic radiological images.
Study: NCT06672120

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Combined, home-based, supervised, video- assisted, endurance and resistance training
Study: NCT06672978

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meropenem-Vaborbactam
Description: Administered as specified in the treatment arm
Study: NCT05592834

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent facilitator trainings
Description: Primary caregivers of children with CP residing in the study setting are trained as parent facilitators by expert physical rehabilitation therapist . Trained parent facilitators then hold fellow caregiver workshops each lasting approximately two hours long and includes between 6-10 caregivers. To ensure quality and consistency of the workshops, the Parent Facilitators follow a detailed manual adapted from the Carer-2-Carer Programme translated into Lusoga, the local language. No expert therapists is involved in the parent facilitator training workshops. Parent facilitator training workshops involve 7 sessions that expose caregivers to understanding CP and how to improve body functioning: session1: what is CP? session2: CP as a way of life, Session 3: Getting my child's body ready to move, Session 4: Eating and drinking a healthy diet, Session 5: communication, Session 6: Play, and Session 7: Central visual impairment.
Study: NCT06672978

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meropenem-Vaborbactam
Description: Administered as specified in the treatment arm

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meropenem-Vaborbactam
Description: Administered as specified in the treatment arm

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: Administered as prescribed by the study physician in accordance with the local marketing authorizations
Study: NCT05592834

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent facilitator trainings
Description: Primary caregivers of children with CP residing in the study setting are trained as parent facilitators by expert physical rehabilitation therapist . Trained parent facilitators then hold fellow caregiver workshops each lasting approximately two hours long and includes between 6-10 caregivers. To ensure quality and consistency of the workshops, the Parent Facilitators follow a detailed manual adapted from the Carer-2-Carer Programme translated into Lusoga, the local language. No expert therapists is involved in the parent facilitator training workshops. Parent facilitator training workshops involve 7 sessions that expose caregivers to understanding CP and how to improve body functioning: session1: what is CP? session2: CP as a way of life, Session 3: Getting my child's body ready to move, Session 4: Eating and drinking a healthy diet, Session 5: communication, Session 6: Play, and Session 7: Central visual impairment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: This group will receive neither the PD nor the PFT interventions but care as usual
Study: NCT06672978

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: Administered as prescribed by the study physician in accordance with the local marketing authorizations

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: Administered as prescribed by the study physician in accordance with the local marketing authorizations
Study: NCT06671223

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Infiltration
Description: The intervention consists of the administration of infiltrations in the affected plantar fascia of participants with a diagnosis of plantar fasciopathy. A drug such as a corticosteroid, PRP or hyaluronic acid will be used, which will be injected under ultrasound guidance to ensure precision at the site of the injury. This intervention aims to reduce inflammation and pain, thus improving the functionality of the foot. Up to three infiltrations will be performed, depending on the patient\&amp;amp;#39;s response to treatment and medical evaluation. The infiltrations will be compared with a control group that will receive conservative treatment without infiltrations, to evaluate the relative effectiveness of this pharmacological intervention in the management of plantar fasciopathy.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Conservative treatment
Description: The control group is used to compare the effectiveness of infiltrations with a non-invasive approach in the treatment of plantar fasciopathy. This group will not receive any infiltration and will focus on conservative interventions.
Study: NCT06671574

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Emotional intelligence and Relaxation techniques
Description: In each session, participants will engage in exercises aimed at recognizing, understanding, and regulating their emotions. These interactive activities will foster personal reflection and group discussion, helping individuals identify emotions in various situations and their impact on behavior. This approach will enhance emotional awareness and equip participants with practical tools for managing stress and anxiety. Various relaxation techniques will also be introduced. Deep breathing exercises will teach participants to calm their minds and bodies, reducing tension. Guided meditation will help them focus inward, promoting mental peace and deep relaxation. Additionally, visualization exercises will encourage imagining calming scenarios, alleviating anxiety and improving overall well-being.