TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04751279

Intervention type: OTHER
Intervention: Blood sample
Description: Blood sample collection of 5 blood sample at the inclusion in the study the samle consite of 5 tubesEthylene Diamine Tetra Acetate (ADTA) of 7 ml

Intervention type: OTHER
Intervention: Blood sample
Description: Blood sample collection of 5 blood sample at the inclusion in the study the samle consite of 5 tubesEthylene Diamine Tetra Acetate (ADTA) of 7 ml

Intervention type: OTHER
Intervention: Blood sample
Description: Blood sample collection of 5 blood sample at the inclusion in the study the samle consite of 5 tubesEthylene Diamine Tetra Acetate (ADTA) of 7 ml

Intervention type: OTHER
Intervention: Blood sample
Description: Blood sample collection of 5 blood sample at the inclusion in the study the samle consite of 5 tubesEthylene Diamine Tetra Acetate (ADTA) of 7 ml
Study: NCT06326151

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interdisciplinary Psychoeducational Programme
Description: This intervention is based on the principle of complementing and integrating both disciplines in order to meet the psychological needs of family carers and to train them in knowledge and strategies aimed at the correct performance of activities of daily living in order to promote the maximum autonomy and functionality of dependent people with cognitive impairment, and that this favours discharge, self-care, improvement of the affective state and quality of life of family carers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Education Programme
Description: Upon discharge from the hospital, at the end of the baseline assessment, caregivers will receive instructions and recommendations for maintaining an active and healthy lifestyle. This will be done by encouraging self-care and good practices in caring for their dependent family member, as part of a health education programme. The benefits of an active lifestyle and general guidelines are emphasized.
Study: NCT05597046

Intervention type: OTHER
Intervention: Interview
Description: Interviews
Study: NCT05590403

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSVPreF3 OA investigational vaccine
Description: One dose administered intramuscularly at Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSVPreF3 OA investigational vaccine
Description: One dose administered intramuscularly at Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSVPreF3 OA investigational vaccine
Description: One dose administered intramuscularly at Day 1.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One dose administered intramuscularly at Day 1.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One dose administered intramuscularly at Day 1.
Study: NCT04727216

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dorsal Root Ganglion Stimulation (DRG-S)
Description: Dorsal Root Ganglion stimulation will be delivered with continuous dosing and 2 different ON/OFF periods to compare effects for each patient.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dorsal Root Ganglion Stimulation (DRG-S)
Description: Dorsal Root Ganglion stimulation will be delivered with continuous dosing and 2 different ON/OFF periods to compare effects for each patient.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dorsal Root Ganglion Stimulation (DRG-S)
Description: Dorsal Root Ganglion stimulation will be delivered with continuous dosing and 2 different ON/OFF periods to compare effects for each patient.
Study: NCT04713345

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Observations
Description: If the patient is included in the Virtual Reality group, they will be asked to observe 1 time per day for 9 days for 5 minutes Virtual Motor Actions (avatar moving in a virtual environment) using a headset. Virtual Reality, followed by 5 minutes of relaxation performed using soothing music played through headphones.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Relaxation
Description: If the patient is included in the Relaxation group, they will be offered 10 minutes of relaxation performed using soothing music played through headphones once a day for 9 days.
Study: NCT04892446

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Administered IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Administered IV
Study: NCT05158803

Intervention type: RADIATION
Intervention: ultrasound and C.T
Description: lung ultrasound in comparison to C.T

Intervention type: RADIATION
Intervention: ultrasound and C.T
Description: lung ultrasound in comparison to C.T
Study: NCT04957524

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iStim TENS unit and Transvaginal Probe
Description: iStim TENS unit and Transvaginal Probe are both commercially available products. TENS units work by delivering small electrical impulses through electrodes either attached to the skin or through a transvaginal probe.~iStim transvaginal probe will be inserted vaginally to provide transvaginal electrical stimulation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iStim TENS unit and Transvaginal Probe
Description: iStim TENS unit and Transvaginal Probe are both commercially available products. TENS units work by delivering small electrical impulses through electrodes either attached to the skin or through a transvaginal probe.~iStim transvaginal probe will be inserted vaginally to provide transvaginal electrical stimulation.
Study: NCT05225168

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: laparoscopic burch colposuspension operation
Description: By pushing the urethra medially, two sutures are placed on the bladder at trigon level and midurethral and suspended on the bilateral iliopectineal ligament and colposuspension is supplied.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: minisling suburethral sling
Description: A vertical vaginal incision is made 1 cm below the external urethral meatus. It is followed by minimal vaginal dissection from the inferior portion of the ascending ramus of the ischiopubic bone to the obturator muscle. The arms of the mesh are fixed on both sides of the obturator internus muscle with the help of a trocar. After leaving a 1-2 mm gap between the mesh and the urethra, the vaginal wall is closed by suturing.
Study: NCT04521166

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hearing aid
Description: Settings in a wearable hearing aid will be adjusted within a clinically-relevant range for two features. The features include wide dynamic range compression and microphone directionality.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hearing aid
Description: Settings in a wearable hearing aid will be adjusted within a clinically-relevant range for two features. The features include wide dynamic range compression and microphone directionality.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hearing aid
Description: Settings in a wearable hearing aid will be adjusted within a clinically-relevant range for two features. The features include wide dynamic range compression and microphone directionality.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hearing aid
Description: Settings in a wearable hearing aid will be adjusted within a clinically-relevant range for two features. The features include wide dynamic range compression and microphone directionality.
Study: NCT06482424

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: intervention group
Description: Actions to be taken to the Intervention Group The researcher will record the state-trait anxiety scale and Pittsburg Sleep Quality Index score on the patient follow-up chart-researcher form at the patient's home at the beginning of the first week and at the end of the fourth week. The aromatic oil given to patients in the intervention group will be placed in 10ml dark glass bottles with droppers and a numbered label will be attached to the bottle.~Procedures to be Performed on the Placebo Group The researcher will record the state-trait anxiety scale and Pittsburg Sleep Quality Index score on the patient follow-up chart-researcher form at the patient's home at the beginning of the first week and at the end of the fourth week. Sesame oil given to patients in the placebo group will be placed in 10 ml dark glass bottles with droppers and a number two label will be attached to the bottle.
Study: NCT06468475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium Sulphate infusion
Description: Magnesium sulphate 24 hours apart by intravenous infusion at 250 mg/kg/dose (0.5 mL/kg/dose of injection magnesium sulphate 50% w/v diluted in 5 mL/kg of 5% glucose) over a duration of half an hour by an infusion pump
Study: NCT04333459

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hataan DNA Vaccine/Puumala DNA Vaccine
Description: Vaccine compared in High and Lose Doses.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hataan DNA Vaccine/Puumala DNA Vaccine
Description: Vaccine compared in High and Lose Doses.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hataan DNA Vaccine/Puumala DNA Vaccine
Description: Vaccine compared in High and Lose Doses.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hataan DNA Vaccine/Puumala DNA Vaccine
Description: Vaccine compared in High and Lose Doses.
Study: NCT04858529

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: investigator-selected taxane/carboplatin/trastuzumab/pertuzumab (TCHP)
Description: investigator-selected taxane/carboplatin/trastuzumab/pertuzumab (TCHP)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: investigator-selected taxane/trastuzumab/pertuzumab (THP)
Description: investigator-selected taxane/trastuzumab/pertuzumab (THP)
Study: NCT04773977

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI362 liquid formulation
Description: Administered by subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI362 lyophilized powder
Description: Administered by subcutaneous injection
Study: NCT05395780

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MAX-40279
Description: MAX-40279 capsule will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MAX-40279
Description: MAX-40279 capsule will be administered orally
Study: NCT05667493

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eplontersen
Description: Eplontersen will be administered by SC injection.
Study: NCT05196724

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mentalization Based Therapy MBT
Description: The focus is on improving the core components of secure attachment, particularly by developing the reflective functioning for all professionals working with children in out-of-home care, which is subsequently proposed to increase the psychosocial adjustment of the child and decrease emotional and behavioral problems. MBT treatment consists of up to 12 weekly sessions with the foster parents and child covering three core components: 1) psycho-education about mentalizing, trauma, and attachment for foster parents; 2) support for reflective practice in the professional network, and 3) mentalization-based therapy for the foster family \[41\].

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: The control group will receive the usual care offered to foster families such as supervision
Study: NCT04665791

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Intranasal inoculation with Neisseria lactamica
Description: Lyophilised Neisseria lactamica will be reconstituted and administered to participants intranasally.
Study: NCT05449873

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation using combined bipolar and monopolar energy deliver with Triple Cooled-Wet electrodes
Description: Radiofrequency ablation will be performed by using triple cooled-wet electrodes. Two or three electrodes will be places around the tumor under ultrasonography (US)-computed tomography (CT)/magnetic resonance (MR) fusion tool guidance. The electrodes will be cooled with saline, and radiofrequency (RF, bipolar mode and switching monopolar mode) will be applied to two of three electrodes at the same time for about 6 to 30 minutes depending on the tumor size. The temperature will be maintained at 90-100 °C.
Study: NCT06029998

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: sub-cutaneous injection of bortezomib for 6-8 cycles of treatment.
Study: NCT06305546

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chlorhexidine Gluconate
Description: For two weeks, all individuals were instructed to use pea-sized gel on their gingiva two times a day. To ensure patient compliance, we assigned patients with log sheets to fill daily on whether they used the gel consistently every day twice a day for 2 weeks. Patients were also instructed to return the container of gel on the day of follow-up.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metronidazole
Description: For two weeks, all individuals were instructed to use pea-sized gel on their gingiva two times a day. To ensure patient compliance, we assigned patients with log sheets to fill daily on whether they used the gel consistently every day twice a day for 2 weeks. Patients were also instructed to return the container of gel on the day of follow-up.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: combination gel (chlorhexidine and metronidazole)
Description: For two weeks, all individuals were instructed to use pea-sized gel on their gingiva two times a day. To ensure patient compliance, we assigned patients with log sheets to fill daily on whether they used the gel consistently every day twice a day for 2 weeks. Patients were also instructed to return the container of gel on the day of follow-up.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: For two weeks, all individuals were instructed to use pea-sized gel on their gingiva two times a day. To ensure patient compliance, we assigned patients with log sheets to fill daily on whether they used the gel consistently every day twice a day for 2 weeks. Patients were also instructed to return the container of gel on the day of follow-up.
Study: NCT04892446

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Administered IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Administered IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Administered either SC or IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Administered either SC or IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Administered orally
Study: NCT06520423

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Urethral stent tube irrigation
Description: During urethroplasty, a Fr3 ureteral catheter will be placed in the reconstructed urethra, with the proximal end extending approximately 2 cm beyond the urethral wound. The distal end will connect to an F6 single-lumen ureter and a urinary bag. On the second postoperative day, the urethra will be irrigated with 5 ml of saline twice daily. This irrigation routine will continue until the catheter is removed.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Urinary catheter drainage
Description: During urethroplasty, intraurethral retention of urethral catheters is used to drain urine from the bladder.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Urinary catheter drainage
Description: During urethroplasty, intraurethral retention of urethral catheters is used to drain urine from the bladder.
Study: NCT05396781

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proflavine
Description: 5-10 ml of proflavine hemisulfate (0.01%) will be sprayed on the esophageal mucosa.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile, Augmented High Resolution Microendoscope
Description: The marHRME will then be inserted through the endoscope and gently placed against the mucosa. Imaging of abnormal tissues will be performed.
Study: NCT05456893

Intervention type: PROCEDURE
Intervention: Procedure: endoscopic biopsy
Description: Per-endoscopic biopsies

Intervention type: PROCEDURE
Intervention: Blood sampling
Description: Blood sampling

Intervention type: PROCEDURE
Intervention: stool sampling
Description: stool sampling
Study: NCT03483220

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI brain
Description: 1. Emotion Regulation Questionnaire (ERQ): A 10-item scale designed to measure respondents' tendency to regulate their emotions in two ways: (1) Cognitive Reappraisal and (2) Expressive Suppression. Respondents answer each item on a 7-point Likert-type scale .~UPPS-P Impulsive Behavior Scale- Short form: The UPPS-P impulsivity scale is a 20-item scale designed to assess five distinct personality traits to impulsive behavior: Negative Urgency, Lack of Perseverance, Lack of Premeditation, Positive Urgency and Sensation Seeking .~Magnetic resonance imaging examination:~The MR examination of brain was done using 1.5T MR scanner (Achieva, Philips Medical Systems, The Netherlands) with a 16 channel head coil without using any sedation.
Study: NCT04892446

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Administered orally
Study: NCT05838040

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: General exercises
Description: General exercise is a structured exercise program designed to help individuals with back pain improve their fitness levels. The program comprises of a series of exercise classes that are led by a physiotherapist. The classes involve a combination of aerobic, strength, and flexibility exercises, and aim to improve overall physical fitness, reduce pain, and improve function. The program is specifically designed for individuals with back pain, and the exercises are tailored to meet the needs of each participant. The Back to Fitness Program is based on the principles of exercise prescription and is intended to be a safe and effective way to manage back pain through exercise.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: General exercises with tranversus abdmoinis contraction
Description: General exercise is a structured exercise program designed to help individuals with back pain improve their fitness levels. The program comprises a series of exercise classes that are led by a physiotherapist. The classes involve a combination of aerobic, strength, and flexibility exercises, and aim to improve overall physical fitness, reduce pain, and improve function. The program is specifically designed for individuals with back pain, and the exercises are tailored to meet the needs of each participant. In addition to these exercises, the Back to Fitness Program includes the activation of the transverse abdominis muscle, which is an important stabilizing muscle in the core. The activation of this muscle is done through specific exercises and techniques, and is intended to improve core stability and reduce the risk of further back injuries.
Study: NCT06494514

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nal-IRI+Oxaliplatin+5-FU/LV+PD-1
Description: These drugs are given on d1, d15, 28 days as one cycle. 6-6 treatment cycles. SBRT is performed in third cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nal-IRI+Oxaliplatin+5-FU/LV+PD-1
Description: These drugs are given on d1, d15, 28 days as one cycle. 6-6 treatment cycles. SBRT is performed in third cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine + albumin-paclitaxel+PD-1
Description: These drugs are given on d1, d8, 21 days as one cycle. 6-6 treatment cycles. SBRT is performed in third cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine + albumin-paclitaxel+PD-1
Description: These drugs are given on d1, d8, 21 days as one cycle. 6-6 treatment cycles. SBRT is performed in third cycles.
Study: NCT00320580

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: norelgestromin/ethinyl estradiol
Study: NCT05231941

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine IV
Description: Bolus and infusion of lidocaine will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine
Description: Bilateral TAP block will be given to these patients
Study: NCT06375720

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lower frequency, shorter period of Tai Chi Chuan
Description: Participants would take 24-form simplified Tai Chi Chuan 1 hour/session, 3 sessions/week for 12 weeks. There were 10 minutes warm-up, 40 minutes Tai Chi Chuan lesson and 10 minutes cool-down exercises in the Tai Chi Chuan training. Besides, they would also take standard health education 0.5 hour/session, 2 sessions/month for 6 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Higher frequency, shorter period of Tai Chi Chuan
Description: Participants would take 24-form simplified Tai Chi Chuan 1 hour/session, 5 sessions/week for 12 weeks. There were 10 minutes warm-up, 40 minutes Tai Chi Chuan lesson and 10 minutes cool-down exercises in the Tai Chi Chuan training. Besides, they would also take standard health education 0.5 hour/session, 2 sessions/month for 6 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lower frequency, longer period of Tai Chi Chuan
Description: Participants would take 24-form simplified Tai Chi Chuan 1 hour/session, 3 sessions/week for 24 weeks. There were 10 minutes warm-up, 40 minutes Tai Chi Chuan lesson and 10 minutes cool-down exercises in the Tai Chi Chuan training. Besides, they would also take standard health education 0.5 hour/session, 2 sessions/month for 6 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Higher frequency, longer period of Tai Chi Chuan
Description: Participants would take 24-form simplified Tai Chi Chuan 1 hour/session, 5 sessions/week for 24 weeks. There were 10 minutes warm-up, 40 minutes Tai Chi Chuan lesson and 10 minutes cool-down exercises in the Tai Chi Chuan training. Besides, they would also take standard health education 0.5 hour/session, 2 sessions/month for 6 months.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Standard Health Education
Description: Participants would take standard health education 0.5 hour/ session, 2 sessions/month for 6 months.
Study: NCT04941365

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: single arm
Description: Blood samples will be collected at baseline(Visit 1), and during therapy at visit 2 (around one month after the treatment starting) and at Visit 3 (around three months after the treatment starting. And, optionally, in case of a disease progression (PD).