TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03912324

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Unipolar voltage subtraction map guided PV isolation group
Description: 1. Pulmonary vein isolation will be performed using a radiofrequency catheter~2. Esophageal temperature will be monitored to prevent esophageal injury~3. Mapping of echocardiographic unipolar voltage subtraction after atrial septal puncture~4. the electrode map data is transferred to the core lab by network to calculate the unipolar voltage subtraction color map (within 10 minutes)~5. Increase radiofrequency ablation time by 2 to 5 seconds in areas with high potential in unipolar voltage subtraction color map~6. Decrease radiofrequency ablation time by 2 to 5 seconds in areas with low potential in unipolar voltage subtraction color map~7. Evaluation of success rate and time of pulmonary vein isolation after bilateral pulmonary vein primary columnar resection~8. Evaluate time to complete isolation after additional ablation~9. Evaluation of Procedure and Ablation time, and perfusion saline dose~10. Rhythm follow-up after the procedure in accordance with the study design.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CT myocardial thickness map guided PV isolation group
Description: 1. Pulmonary vein isolation will be performed using a radiofrequency catheter~2. Esophageal temperature will be monitored to prevent esophageal injury.~3. Prepared myocardial thickness map with CT DICOM images conducted prior to procedure.~4. Increase radiofrequency ablation time by 2 to 5 seconds in thick areas in CT myocardial thickness map~5. Decrease radiofrequency ablation time by 2 to 5 seconds in thin areas in CT myocardial thickness map~6. Evaluation of success rate and time of pulmonary vein isolation after bilateral pulmonary vein primary columnar resection~7. Evaluate time to complete isolation after additional ablation~8. Evaluation of Procedure time, Ablation time, and perfusion saline dose~9. Rhythm follow-up will be performed after the procedure in accordance with the aforementioned study design.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Empirical PV isolation group
Description: 1. Pulmonary vein isolation will be performed using a radiofrequency catheter~2. Esophageal temperature will be monitored to prevent esophageal injury.~3. The procedure is performed by adjusting radiofrequency energy according to the traditional method and experience of the practitioner.~4. Evaluation of success rate and time of pulmonary vein isolation after bilateral pulmonary vein primary columnar resection~5. Evaluate time to complete isolation after additional ablation~6. Evaluation of Procedure time, Ablation time, and perfusion saline dose~7. Rhythm follow-up will be performed after the procedure in accordance with the aforementioned study design.
Study: NCT05288920

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency pulsed mode on dorsal root ganglion combined with transforaminal steroids injection
Description: Radiofrequency pulsed mode on dorsal root ganglion combined with transforaminal steroids injection
Study: NCT05538377

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Focal Vibration
Description: This group will receive a multicomponent exercise program based on specific literature for effective training. In addition, this group will perform the strength and endurance exercises with focal vibration on the vastus internus, externus and biceps femoris. There will be 2 sessions per week, with a duration of 60 minutes per session and a treatment duration of 6 months.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: This group will receive the same multicomponent exercise program than the other group based on specific literature for effective training. There will be 2 sessions per week, with a duration of 60 minutes per session and a treatment duration of 6 months.
Study: NCT05667610

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Immune-supportive diet
Description: The intervention includes a immune-supportive diet over a period of 4 months

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Immune-supportive diet
Description: The intervention includes a immune-supportive diet over a period of 4 months
Study: NCT06436222

Intervention type: DEVICE
Group type: OTHER
Intervention: HVNI
Description: Preterm infants with gestational age (GA) less than 32 weeks or birth weight less than 1500 grams. The infant has moderate respiratory distress (Downe score ≤ 6) detected within 24 hours after birth.

Intervention type: DEVICE
Group type: OTHER
Intervention: HVNI
Description: Preterm infants with gestational age (GA) less than 32 weeks or birth weight less than 1500 grams. The infant has moderate respiratory distress (Downe score ≤ 6) detected within 24 hours after birth.
Study: NCT06159244

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stool withdrawal
Description: stool withdrawal at day 0 and day 7

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: stool withdrawal
Description: stool withdrawal at day 0 and day 7

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stool withdrawal
Description: stool withdrawal at day 0 and day 7
Study: NCT04424394

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DualStim Therapy
Description: 6 DualStim Therapies over a period of 7 weeks.
Study: NCT05793372

Intervention type: OTHER
Intervention: Retrospective study of clinical features
Description: Retrospective study of clinical features
Study: NCT06190418

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Loaded sit to stand strengthening exercise
Description: This Group will be given with the wieghted vest equal to that of 1RM for each child and Sit-to-Stand Strengthening Excerise will be given 3 times per week for 6 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Unloaded sit to stand strengthening exercise
Description: This Group will be given with the Sit-to-Stand Strengthening Excerise without any external load for 3 times per week for 6 weeks
Study: NCT06401252

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based intervention
Description: • The mindful mediators are asked to act as neutral observers who view the world as it is, without reactions, judgments, and evaluations. They quietly attend to, note, and let go of every internal external stimulus such as thought, feeing, sensation, sound, idea that enters awareness. They do not try to think about, push away, and do anything with these stimuli experienced and do not have to figure out the connections between each 19 stimuli. They simply let each stimulus come and go and wait for the next stimulus. They do not have to be concerned about distractions. Each time they are distracted, they note it as yet another passing stimulus (Ah, a distraction... how interesting)
Study: NCT05546749

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: RelieVRx
Description: The virtual reality device that will be piloted is called RelieVRx, which incorporates evidence-based principles of cognitive behavioral therapy, mindfulness, and pain neuroscience education into an immersive and enhanced biofeedback experience. RelieVRx includes breathing training and relaxation response exercises that activate the parasympathetic nervous system. RelieVRx was designed for at-home use and comes with a sequence of daily immersive experiences.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham VR
Description: The sham VR control is a non-immersive set of 56 daily virtual experiences, tuned to the length of the RelieVRx.
Study: NCT04869189

Intervention type: DEVICE
Group type: OTHER
Intervention: JJVC Marketed Contact Lens
Description: Acuvue Oasys® 1-Day

Intervention type: DEVICE
Group type: OTHER
Intervention: JJVC Marketed Contact Lens
Description: Acuvue Oasys® 1-Day
Study: NCT04759898

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: transcranial direct current stimulation (noninvasive recording)
Description: Subjects will enter the EEG lab and be seated in a chair. The 26-electrode EEG array will be placed using a conductive paste. The electrodes will be connected to a clinical grade EEG machine used in standard of care routine EEG monitoring. Next, a soft cloth cap will be placed over the subject's head with the tDCS electrodes pre-positioned in place. The cap will be positioned so that the tDCS electrodes cover the scalp without disturbing the underlying EEG electrodes. Conducting gel will be applied in direct contact with the scalp to facilitate stimulation. In addition, lidocaine jelly will be added topically to provide local anesthesia. The tDCS electrodes will be connected to a low-current generator. Participants receive 2.0 milliamps in electrical stimulation from the tDCS machine for 20 minutes. The device will be manually controlled by study personnel assisting with the experiment. A virtual reality environment will be utilized to collect kinematic data during the study.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham transcranial direct current stimulation (noninvasive recording)
Description: Subjects receiving sham undergo the same setup as the stimulation group with the exception that sham subjects experience stimulation for one minute only (30 second ramp-up to 2 milliamps immediately followed by 30 second ramp-down to 0 milliamps for the remaining 19 minutes). This provides similar sensory feedback to sham subjects that treatment subjects experience. The same electrode array, soft cloth cap, conducting gel application, and lidocaine are applied as in a stimulation subject. The tDCS electrodes will be connected to a low-current generator. A virtual reality environment will be utilized to collect kinematic data during the study.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation (invasive recording)
Description: Subjects are brought into the operating room. The scalp is prepped with a sterilizing solution. Following infiltration with local anesthetic and incision, a 6-contact electrocorticography strip is inserted into the burr hole covering primary motor cortex. Electrocorticography strip terminals are connected to an amplifier for signal recording. Gas-sterilized transcranial direct current stimulation electrodes are placed on the scalp directly overlying primary motor cortex. tDCS electrodes are connected to a low-current generator. During electrocorticographic recording, stimulation is turned on while subjects are asked to flex each arm. At the conclusion of the experiment, the electrocorticography strip and tDCS electrodes are removed and the surgery proceeds as planned.
Study: NCT05242809

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group-based PFMT group
Description: The intervention group receives PFMT supervision in groups of about 6-8 women
Study: NCT04424394

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DualStim Therapy
Description: 6 DualStim Therapies over a period of 7 weeks.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Umbilical cord-derived Wharton's Jelly
Description: 2 intracavernosal injections over a period of 7 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Saline
Description: 2 intracavernosal injections over a period of 7 weeks.
Study: NCT06513130

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Geriatric assessment in the 7 days following ICU discharge.
Description: ICU survivors will be assessed by a geriatric physician, in a global (clinical, physical, psyochological and social) approach at the end of the ICU stay or in the 7 days following ICU discharge.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No geriatric assessment in the 7 days following ICU discharge.
Description: No geriatric assessment in the 7 days following ICU discharge.
Study: NCT04820114

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Proprioceptive wrist exercises
Description: Exercises for recognition of writs position and thumb force sense.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Wrist exercises
Description: Passive and active exercises for improve range of motion in flexion, extension, ulnar and radial deviation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wrist exercises
Description: Passive and active exercises for improve range of motion in flexion, extension, ulnar and radial deviation
Study: NCT05302869

Intervention type: OTHER
Intervention: None intervention
Description: None intervention

Intervention type: OTHER
Intervention: None intervention
Description: None intervention
Study: NCT06121076

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SDM-EBP training
Description: A 20-hour tailored SDM combined with EBP training program consisting of a seven-hour lecture and a four-hour hands-on practice session.

Intervention type: OTHER
Group type: OTHER
Intervention: SDM-EBP training
Description: A 20-hour tailored SDM combined with EBP training program consisting of a seven-hour lecture and a four-hour hands-on practice session.
Study: NCT06264466

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: POEM with Speedboat Ultraslim
Description: POEM procedures, with or without fundoplication, will be conducted by expert endoscopists who have undergone prior training in the utilization of the ultraslim Speedboat. Incisions, whether anterior or posterior, submucosal tunneling, and myotomy will be performed using the Bipolar Radiofrequency Ablation (RFA) integrated into the device's tip. Additionally, for vessel coagulation, the microwave energy integrated into the device's tip will be employed. Successful myotomy will be confirmed by passage of the endoscope through the esophagogastric junction (EGJ) without restriction.
Study: NCT04930120

Intervention type: OTHER
Intervention: Inter ICU long distance patient transfer
Description: Individual or grouped transportation between ICU of severely ill patients using ambulance, plane, helicopter, train or boat, with specialist medical assistance.
Study: NCT04293224

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DGA Mediterranean diet pattern, energy balance
Description: Foods and beverages will be provided for participants for eight weeks. During the controlled feeding portion of the study the DGA Mediterranean diet pattern will be based on the Table A7-1 of the 2015 Dietary Guidelines for Americans which outlines daily nutritional goals for age-sex groups based on Dietary Reference Intakes (DRI) and dietary guidelines recommendations.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DGA Mediterranean diet pattern, negative energy balance
Description: Foods and beverages will be provided for participants for eight weeks. During the controlled feeding portion of the study the DGA Mediterranean diet pattern will be based on the Table A7-1 of the 2015 Dietary Guidelines for Americans which outlines daily nutritional goals for age-sex groups based on Dietary Reference Intakes (DRI) and dietary guidelines recommendations

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TAD diet pattern, negative energy balance
Description: Foods and beverages will be provided for participants for eight weeks. During the controlled feeding portion of the study the be based on evidence collected from What We Eat in America (WWEIA) data. Based on this data the participants will be provided a diet that reflects American dietary trends.
Study: NCT05288920

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Transforaminal injection of Steroids alone
Description: Transforaminal injection of Steroids alone
Study: NCT05791773

Intervention type: PROCEDURE
Intervention: the robot assisted total knee arthroplasty
Description: the robot assisted total knee arthroplasty

Intervention type: PROCEDURE
Intervention: the conventional jig-based total knee arthroplasty
Description: the conventional jig-based total knee arthroplasty
Study: NCT06404658

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Genicular nerve block
Description: patients who receive Genicular nerve block with spinal anathesia .

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Genicular nerve block
Description: patients who receive Genicular nerve block with spinal anathesia .
Study: NCT06299020

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: intermittent fasting
Description: fasting from predawn to sunset (no eating and no drinking), for approximately 16 hours.
Study: NCT05066750

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindful breathing
Description: Participants watch a 10 minute mindful breathing video

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control video
Description: Participants watch a 10 minute control video
Study: NCT06113809

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Description: Palbociclib is a CDK4/6 inhibitor.~Palbociclib, 125 mg, (pediatric dose 75mg/m2 up to 125mg) daily for 21 days out of every 28 days, PO (orally) starting 14 days prior to Pembrolizumab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab is a PD-1 blocking antibody.~Given 14 days following Palbociclib: Pembrolizumab, 200 mg, once every three weeks, intravenously (IV)
Study: NCT05851495

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: physiotherapist-led groups, home-based follow up groups
Description: The group involved in physiotherapists-led groups was shown the exercises in practice and under the supervision of the physiotherapist, the patients applied their exercises throughout their treatment. Home-based follow up groups, after the exercise training was given to the patients with a physiotherapist, daily text messages (SMS) were sent to the patients and the patients were reminded to do the exercises

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: physiotherapist-led groups, home-based follow up groups
Description: The group involved in physiotherapists-led groups was shown the exercises in practice and under the supervision of the physiotherapist, the patients applied their exercises throughout their treatment. Home-based follow up groups, after the exercise training was given to the patients with a physiotherapist, daily text messages (SMS) were sent to the patients and the patients were reminded to do the exercises
Study: NCT05819502

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Restylane line of injectables
Description: Restylane fillers are manufactured by Q-Med AB, part of the Galderma Group.
Study: NCT05622656

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Dexmedetomidine 0.0005%

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% Sodium Chloride Solution
Study: NCT05642793

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: proactive Anti-VEGF (conbercept) use
Description: preventive intravitreal injection of conbercept 2 weeks after vitrectomy, and repeat at 5 weeks and 8 weeks if either of the following is present: intravitreal VEGF concentration at 2 weeks postop is higher than 100 pg/ml, or clinical presentation of DME, VH or NVG.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: passive Anti-VEGF (conbercept) use
Description: No intravitreal injection of conbercept is used until the patient present with postoperative DME, VH, NVG
Study: NCT06190717

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EchoMark/EchoSure
Description: Subjects assigned to the Diagnostic Arm will have the EchoMark implanted at the time of AVF creation. The subject will return every 2 weeks for a follow-up assessment to include an EchoSure scan until fistula maturation and/or permanent access use is achieved. The EchoSure scans are to be reviewed by the investigator(s) or delegated study staff and aid in the determination when a further assessment, including a physical exam, is required to determine cannulation clearance or if an intervention(s) may be required to prevent failure of fistula maturation. All physical exams will include assessing the fistula for bruit and thrill. The subject's medical history will be reviewed at each visit and will include all interventions, cannulation attempts, and adverse event reporting.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Subjects are assessed using standard of care per KDOQI guidelines, which includes a physical exam at the 2-week follow-up visit and at the 4-6-week follow-up visit. All follow-up visits will include an assessment of adverse events and medical history review to include all interventions, cannulation attempts, and laboratory results. If evaluation yields an abnormal finding, subjects will undergo a Duplex ultrasound assessment and treatment under the institution's standard of care. All SOC Arm subjects will be followed per the institution's standard of care until fistula maturation occurs and/or permanent access use is achieved but no more frequently than once per month.
Study: NCT05486598

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL8326 tablets
Description: Sequence A group: on the 1st day, take a single dose of AL8326 tablets on an empty stomach. On the 15th day, take a single dose of AL8326 tablets after meals.~Sequence B group: on the 1st day after meal, take a single dose of AL8326 tablets; on the 15th day, take a single dose of AL8326 tablets on an empty stomach.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL8326 tablets
Description: Sequence A group: on the 1st day, take a single dose of AL8326 tablets on an empty stomach. On the 15th day, take a single dose of AL8326 tablets after meals.~Sequence B group: on the 1st day after meal, take a single dose of AL8326 tablets; on the 15th day, take a single dose of AL8326 tablets on an empty stomach.
Study: NCT06521619

Intervention type: PROCEDURE
Intervention: Femoral and sciatic nerve blocks
Description: Patients receiving Adductor canal block and infiltration of posterior capsule of knee
Study: NCT06598553

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Projet Jeune Leader Comprehensive Sexual Education
Description: PJL provides trained educators to deliver a 22 week comprehensive sexual education (CSE) curriculum in participating middle schools. All adolescents enrolled in the school receive the CSE program.
Study: NCT06203873

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Biodegradable occluder
Description: Patients assigned in this group will receive PFO occlusion with a biodegradable occluder.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Metal occluder
Description: Patients assigned in this group will receive metal occluder for PFO occlusion
Study: NCT05824559

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ME-344
Description: ME-344 will be administered intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab will be administered intravenously (IV)