TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04034004

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: A well-validated brief meditation-based mental training regimen \[four sessions; 20 min/session\] is used to teach patients to independently practice closing their eyes and take a deep breath every few minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: A well-validated brief meditation-based mental training regimen \[four sessions; 20 min/session\] is used to teach patients to independently practice closing their eyes and take a deep breath every few minutes.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naloxone
Description: A 0.15 mg/kg bolus dose of naloxone (Naloxone hydrochloride, Amphastar Pharmaceuticals, Inc., Rancho Cucamonga, California) in 25ml normal saline will be administered over 10 minutes. The investigators also will administer a supplementary IV infusion dose of 0.1mg/kg/hour naloxone immediately after bolus infusion will cease till the end of the experiment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naloxone
Description: A 0.15 mg/kg bolus dose of naloxone (Naloxone hydrochloride, Amphastar Pharmaceuticals, Inc., Rancho Cucamonga, California) in 25ml normal saline will be administered over 10 minutes. The investigators also will administer a supplementary IV infusion dose of 0.1mg/kg/hour naloxone immediately after bolus infusion will cease till the end of the experiment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Saline
Description: A 0.15 mg/kg bolus dose of saline in 25ml normal saline will be administered over 10 minutes. The investigators also will administer a supplementary IV infusion dose of 0.1mg/kg/hour saline immediately after bolus infusion will cease till the end of the experiment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Saline
Description: A 0.15 mg/kg bolus dose of saline in 25ml normal saline will be administered over 10 minutes. The investigators also will administer a supplementary IV infusion dose of 0.1mg/kg/hour saline immediately after bolus infusion will cease till the end of the experiment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation
Description: A well-validated brief meditation-based mental training regimen \[four sessions; 20 min/session\] is used to teach patients to independently practice closing their eyes and take a deep breath every few minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation
Description: A well-validated brief meditation-based mental training regimen \[four sessions; 20 min/session\] is used to teach patients to independently practice closing their eyes and take a deep breath every few minutes.
Study: NCT05742880

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: 6 Minute Walking Test
Description: 6 Minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: 6 Minute Walking Test
Description: 6 Minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: 6 Minute Walking Test
Description: 6 Minute walking test

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Blood gas analysis
Description: Blood gas analyisis

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Blood gas analysis
Description: Blood gas analyisis
Study: NCT05988879

Intervention type: DRUG
Intervention: Peginterferon alfa-2b Injection
Description: The pegylated interferon α-2b injection is administered subcutaneously at a dose of 180ug once a week.
Study: NCT06406023

Intervention type: OTHER
Group type: OTHER
Intervention: Conventional treatment
Description: Hot pack will be applied for 10 minutes. AROM's of Hip (5 reps x 2 sets each). Piriformis stretch 3 reps x 20 sec hold x 2 sets. SLR (5reps x 10 sec hold x 2 sets). Sciatic nerve stretch (5 reps x 10 sec hold x 2 sets) for 3 days/ week for 2 weeks.~Strengthening exercises will be performed after 2 weeks of previous intervention of Hip abductors (Hip abduction with band in sitting, standing, side-lying hip raise), and hip extensors (Gluteal bridges, Prone hip extension, Prone hams curl). (5 reps x 2 sets each).~SLR (5 reps x 10 sec hold x 2 sets) each exercise will be performed 3 days/ week for 2 weeks.~Total treatment protocol will be followed for 4 weeks. Each session will be of 30 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional treatment
Description: Hot pack will be applied for 10 minutes. AROM's of Hip (5 reps x 2 sets each). Piriformis stretch 3 reps x 20 sec hold x 2 sets. SLR (5reps x 10 sec hold x 2 sets). Sciatic nerve stretch (5 reps x 10 sec hold x 2 sets) for 3 days/ week for 2 weeks.~Strengthening exercises will be performed after 2 weeks of previous intervention of Hip abductors (Hip abduction with band in sitting, standing, side-lying hip raise), and hip extensors (Gluteal bridges, Prone hip extension, Prone hams curl). (5 reps x 2 sets each).~SLR (5 reps x 10 sec hold x 2 sets) each exercise will be performed 3 days/ week for 2 weeks.~Total treatment protocol will be followed for 4 weeks. Each session will be of 30 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instrument assisted soft tissue mobilization
Description: Instrument assisted soft tissue mobilization IASTM with Graston tool along with conventional treatment in first 6 sessions. Apply hot pack for 10 mins on low back as passive warm up then AROM's of Hip (5 reps x 2 sets each) will be performed. Apply Graston tool at 30-60 degrees angle along the length of following muscles Piriformis, Gluteus medius and Hamstrings after applying emollient for 40-120 seconds.
Study: NCT05802043

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Stimulating Interventions
Description: a quasi-experimental research design.The study subjects of group 1, the study group, will receive the proposed interventions, the cognitive stimulation interventions through small groups of study subjects receiving 12 sessions of group activities (2 sessions/week, approximately 45- 60 minutes/session). A group size of 6 to 8 will be conducted. The interventions group will be conducted in activity rooms within the elderly club.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Stimulating Interventions
Description: a quasi-experimental research design.The study subjects of group 1, the study group, will receive the proposed interventions, the cognitive stimulation interventions through small groups of study subjects receiving 12 sessions of group activities (2 sessions/week, approximately 45- 60 minutes/session). A group size of 6 to 8 will be conducted. The interventions group will be conducted in activity rooms within the elderly club.
Study: NCT05376631

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fresh gas flow of 5 L/min
Description: A fresh gas flow of 5 L/min is used during emergence from general anesthesia.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fresh gas flow of 10 L/min
Description: A fresh gas flow of 10 L/min is used during emergence from general anesthesia.
Study: NCT06222671

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 608
Description: 608 subcutaneous (SC) injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 608
Description: 608 subcutaneous (SC) injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo subcutaneous (SC) injection.
Study: NCT06126887

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Incrediwear Daytime Back Brace
Description: Incrediwear Daytime Back Brace

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Incrediwear Sham Daytime Back Brace
Description: Incrediwear Sham Daytime Back Brace

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Control Daytime Back Brace
Description: Control Daytime Back Brace

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Incrediwear 24 Hour Back Brace
Description: Incrediwear 24 Hour Back Brace
Study: NCT05623423

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: (Admira Fusion, Voco GmbH, Germany)
Description: cavity margins will be extended to the proximal area, incisal edge, facial and lingual surfaces All enamel margins will be beveled at a 45° angle to the external cavosurface.(approximately 0.5-2.0 mm) An impression for the upper anterior teeth will be taken to produce a silicon palatal index The proximal margins of the restorations will be achieved using the Unica anterior matrix teeth will be etched using 37% phosphoric acid gel for 30 s then rinsed with air water for 20 s A single coat of universal bond cured using and LED light curing unit for 10 s Using the chosen enamel shade of the ORMOCER Resin Composite a thin layer (0.5-1 mm) Unica matrix will used to produce the proximal margins of the restorations Contouring, finishing and polishing of the restoration will be done Dental floss and finishing strips will be used Rubber dam will then be removed and occlusion will be checked using an articulating paper

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Methacrylate Based Composite
Description: The exact same steps as in the intervention will be done but using the chosen shades of Methacrylate Based Composite Resin. (Ceram.X Spectra ST, Dentsply Sirona, UK)
Study: NCT06149871

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: resistance, aerobic, and flexibility exercises
Study: NCT06583629

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Freedom Technique
Description: EFT is a self-help technique that incorporates conscious awareness of thoughts and feelings with a gentle touch involving tapping with fingertips on acupuncture/acupressure points on the face, hands, and body. EFT also helps relieve primary physical and emotional symptoms. Gary Craig created EFT, which involved lightly tapping on the body on 12 acupressure sites (also known as acupoints). This acupoints are situated along the body's meridians, or virtual energy channels
Study: NCT05651906

Intervention type: PROCEDURE
Intervention: Kidney Transplantation
Description: Kidney transplantation as the best option for patients with end-stage kidney disease.
Study: NCT04786795

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Compound Azintamide Enteric-coated Tablets
Description: the experimental group takes Compound Azintamide Enteric-coated Tablets.They were registered before medication and on days 14 and 28 after medication, and gastrointestinal symptoms were assessed at each follow-up visit

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oryz-aspergillus Enzyme both Pancreatin Tablet and Ursodeoxycholic Acid Tablets
Description: the control group takes Oryz-aspergillus Enzyme both Pancreatin Tablet and Ursodeoxycholic Acid Tablets. They were registered before medication and on days 14 and 28 after medication, and gastrointestinal symptoms were assessed at each follow-up visit
Study: NCT05801679

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Fifteen minutes after ICU arrival, subjects will be administered placebo (2 mg/kg assuming a twitch count of 2-4 of 4 or 4mg/kg assuming a twitch count less than 2 of 4) by the anesthesia provider. Five minutes after administration, a quantitative neuromuscular monitor (TetraGraph, Senzime, Uppsala, Sweden) will be applied and the TOF ratio will be recorded.
Study: NCT06339788

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HD-P023
Description: Single dose administration of HD-P023

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Teneligliptin
Description: Single does administration of Teneligliptin and Empagliflozin High

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Empagliflozin
Description: Single does administration of Teneligliptin and Empagliflozin High
Study: NCT05000359

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: text messaging intervention
Description: Ten AYA survivors will be recruited to participate in the expanded 12-week text messaging intervention.
Study: NCT05665348

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ipilimumab Injection
Description: Administration of a combine treatment by atezolizumab and bevacizumab, with addition of ipilimumab for patients enrolled in the experimental arm

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atezolizumab Injection
Description: One of the standard treatment's product for HCC management

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab Injection
Description: One of the standard treatment's product for HCC management

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bevacizumab
Description: One of the standard treatment's product for HCC management

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: One of the standard treatment's product for HCC management
Study: NCT05143580

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive therapy
Description: * The anesthesiologist will provide the patient with instructions for preoperative anesthesia.~* The operating room nurses will introduce the operating room environment and surgical care instructions to the patient.~* Provide a manual for disease health education.~* Provide post-operative care and environmental imaging materials, explain the importance of intensive care unit routines and related equipment, indwelling pipelines, related nursing staff, post-operative care methods, and provide imaging and health education manuals for explanation.~* Use gamification to evaluate: pain relief skills, lung expansion skills.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Routine care
Description: * The anesthesiologist will provide the patient with instructions for preoperative anesthesia.~* The operating room nurses will introduce the operating room environment and surgical care instructions to the patient.~* Provide a manual for disease health education.
Study: NCT06461949

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Dupilumab (Dupixent) is a human monoclonal antibody administered via subcutaneous injection to treat various conditions such as Chronic Rhinosinusitis with Nasal Polyps, Asthma and Eosinophilic Esophagitis.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dupilumab
Description: Dupilumab (Dupixent) is a human monoclonal antibody administered via subcutaneous injection to treat various conditions such as Chronic Rhinosinusitis with Nasal Polyps, Asthma and Eosinophilic Esophagitis.
Study: NCT05209256

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Chemotherapy
Description: Patients in the alflutinib group received alflutinib (80 mg daily) until disease progression, unacceptable toxicity, or death.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alflutinib plus chemotherapy
Description: Those in the combination group received concurrent alflutinib (80 mg daily), as well as carboplatin (area under the curve \[AUC\] of 5 on day 1) and pemetrexed (500 mg/m2 on day 1) in a 3-week cycle for up to four cycles, followed by maintenance on alflutinib and pemetrexed until disease progression, unacceptable toxicity, or death.
Study: NCT04988529

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone-based serious game intervention
Description: Smartphone-based serious game intervention consists in the use of a serious game designed specifically to improve depressive symptoms. The psychological content consists of CBT intervention with the following psychotherapeutic components: Motivation for change, Psychoeducation, Cognitive Flexibility, Behavioural Activation, and positive psychotherapeutic strategies. To encourage physical activity, the serious game incorporates a mixed reality through physical activities such as taking a walk in real life affects aspects inside the game.
Study: NCT05796895

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Videogame
Description: Children will be provided with the videogame for eight weeks, through which they will be taught symptom management strategies. Children and their parents will be telephoned every week by a nurse to inquire whether children performed the strategies taught to them and if they have any health concerns. Children and parents can also call the nurse educator if they have any questions. Their queries/concerns will be responded to by the nurse educator in consultation with the clinical health experts (doctors and nurses) in the research team.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: WhatsApp
Description: Children will be provided with weekly WhatsApp messages on healthy behaviors. Children and their parents will be telephoned every week by a nurse to inquire whether they have any health concerns. Children and parents can also call the nurse educator if they have any questions. Their queries/concerns will be responded to by the nurse educator in consultation with the clinical health experts (doctors and nurses) in the research team.
Study: NCT06168682

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SuperNO2VA™ Et by Vyaire Medical, Inc.
Description: SuperNO2VA™ Et provides a nCPAP between 3 to 10 cmH20 using a oxygenflowrate of 6l/O2

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: nasal oxygen cannula
Description: Standard Operating Procedure (SOP) for endoscopy: Using a nasal oxygen cannula with oxygenflowrate of 6l/O2
Study: NCT05541679

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Right ventricular septal pacing followed by left bundle branch area pacing
Description: All patients will undergo implantation of right ventricular septal lead, left bundle branch area lead, and atrial lead in the absence of permanent atrial fibrillation with a CRT-pacing generator. Patients will be randomized to pacing protocols based on group assignment and crossover during the study.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Left bundle branch area pacing followed by right ventricular septal pacing
Description: All patients will undergo implantation of right ventricular septal lead, left bundle branch area lead, and atrial lead in the absence of permanent atrial fibrillation with a CRT-pacing generator. Patients will be randomized to pacing protocols based on group assignment and crossover during the study.
Study: NCT05380440

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Families Actively Improving Relationships (FAIR)
Description: FAIR is a behavioral intervention for the treatment of parental substance abuse and child neglect for families involved in the child welfare system. This project will adapt the existing FAIR intervention for prevention. FAIR involves four major treatment components, supported by ongoing purposeful engagement : (1) Substance use treatment including contingency management and positive reinforcement, frequent urinalysis, relationship building, day planning, healthy environments and peer choices, and refusal skills; (2) Mental health treatment including cognitive behavioral therapy, developing healthy coping skills, emotion regulation skills, exposure therapy, and referral for medication management; (3) Parent management training including parenting skills, nurturing and attachment, reinforcement, emotion regulation, supervision, structure, non-harsh discipline, and nutrition; and (4) Resource building and provision of ancillary supports including assistance with housing and employment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Case Management and Referral
Description: Parents will be referred for a substance abuse and mental health assessment with possible resulting treatment. Child Welfare treatment plans typically include a series of recommendations, including parenting classes, securing safe housing, psychosocial treatment (e.g., domestic violence), accessing self-sufficiency services (e.g., food stamps, WIC), securing employment or education, and meeting court dates and requirements.
Study: NCT06132061

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: universal prevention
Description: Health education related to depression to strengthen the participants' self-care skills to reduce sub-health risk factors.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: selective prevention
Description: Psychosocial interventions (including but not limited to cognitive behavioral therapy, acceptance commitment therapy, mindfulness training) aimed at risk factors to prevent more severe depressive symptoms.
Study: NCT05606276

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eccentric Exercise
Description: Individuals will do a randomized crossover intervention involving maximal eccentric contractions (2 sets of 6 per leg; experimental condition)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cycle ergometer
Description: Individuals will do a randomized crossover intervention involving cycling (active control) exercise
Study: NCT06164834

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clopidogrel 75 mg
Description: Clopidogrel 75 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clopidogrel 75 mg
Description: Clopidogrel 75 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clopidogrel 75 mg
Description: Clopidogrel 75 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegoprazan 25 mg
Description: Tegoprazan 25 mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esomeprazole 20mg
Description: Esomeprazole 20 mg tablet
Study: NCT06526819

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SMP3124LP
Description: Liposomal encapsulation formulation of SMP-3124

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SMP3124LP
Description: Liposomal encapsulation formulation of SMP-3124
Study: NCT05534958

Intervention type: DEVICE
Intervention: Accexible
Description: Speech Analysis
Study: NCT05421013

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STP705
Description: STP705 targets TGFB-1 and COX-2 mRNA respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STP705
Description: STP705 targets TGFB-1 and COX-2 mRNA respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STP705
Description: STP705 targets TGFB-1 and COX-2 mRNA respectively.
Study: NCT06106191

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness meditation
Description: Ordinary activities like breathing, eating, and walking are turned into a meditation by creating greater awareness of the moment-to-moment sensations, emotions, thoughts and behaviors that arise during these activities.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Perspectives on pain
Description: Understanding pain from a mind-body perspective and viewing pain as a stressor on physical sensations, thoughts, emotions, and behavior.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Discussion
Description: Discussion on patients' use of mindfulness to work with pain and pain-themed meditations.
Study: NCT06238778

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HDV-Lispro
Description: HDV-L will be used as the mealtime insulin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lispro
Description: Lispro will be used as the mealtime insulin