TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05948215

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Jing Si Herbal Tea Liquid Packet
Description: The preliminary data demonstrated that the Jing Si Herbal Tea Liquid Packet may improve gastrointestinal symptoms and anxiety in patients with Coronavirus disease 2019(COVID-19). Therefore,this study aims to investigate the impact of the Jing Si Herbal Tea Liquid Packet on psychophysical burden and metabolites of microbiota in patients with FD through a double-blind randomized manner.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Jing Si Herbal Tea Liquid Packet Placebo
Description: Compared with the improvement effect of Jing Si Herbal Tea Liquid Packet, to avoid participants thinking that the improvement is due to psychological effects.
Study: NCT04758962

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 1 µg CoV2 SAM (LNP)
Description: 2 doses of 1 µg CoV2 SAM (LNP) vaccine in 0,1-month schedule, administered IM in the deltoid of the non-dominant arm.
Study: NCT05464537

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Unipolar Polarity Switch Left
Description: 10-15 Left veins are randomized to Unipolar Polarity Shift, right veins are randomized to CAI-OPR-LAAP

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Unipolar Polarity Switch Right
Description: 10-15 cases randomized to CAI-OPR-LAAP on left veins, and Unipolar Polarity Switch on right veins
Study: NCT06270680

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vision Edge Pro
Description: Each dose will consist of one supplement capsule containing 10 mg lutein, 2 mg zeaxanthin, 10 mg mesozeaxanthin, 50mg EPA, 250mg DHA. Capsules are to be taken orally, once daily with a meal. Duration of supplementation will last approximately 2 - 5 months, depending on the length of the athletic seasons for the sports recruited.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A sunflower oil placebo containing 380 mg of sunflower oil
Study: NCT04798287

Intervention type: DRUG
Intervention: Tofacitinib
Description: First eligible prescription for treating rheumatoid arthritis (RA)

Intervention type: DRUG
Intervention: TNF Inhibitor
Description: First eligible prescription for treating rheumatoid arthritis (RA)
Study: NCT05387499

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NP-011 (Single Ascending Dose Phase)
Description: The participants will receive assigned single dose of NP-011 after a minimum 8 hour fast on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NP-011 (Multiple Ascending Dose Phase)
Description: The participants will receive assigned dose of NP-011 after a minimum 8 hour fast once daily for 7 days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: NP-011 (Placebo)
Description: The participants will receive single dose of NP-011 after a minimum 8 hour fast on Day 1 in Single Ascending Dose part and will receive once daily for 7 days after a minimum 8 hour fast in Multiple Ascending dose part of the study
Study: NCT06072898

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin (\[3-\[2-(dimethylamino)ethyl\]-1H-indol-4-yl\] dihydrogen phosphate), 25mg PO.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin (\[3-\[2-(dimethylamino)ethyl\]-1H-indol-4-yl\] dihydrogen phosphate), 25mg PO.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Microcrystalline cellulose
Description: MCC (excipient), 25mg PO.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supportive psychotherapy
Description: Supportive psychotherapy in the form of reassurance, integration, and de-escalatory techniques (if needed). Facilitating rapport and a positive environment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supportive psychotherapy
Description: Supportive psychotherapy in the form of reassurance, integration, and de-escalatory techniques (if needed). Facilitating rapport and a positive environment.
Study: NCT05024292

Intervention type: PROCEDURE
Intervention: rapid local ischemic postconditioning (RL-IPostC)
Description: with 5 circules of balloon inflations in the ipsilateral internal carotid artery, each circulation includes inflation lasting 15 seconds followed by 15 seconds of deflation
Study: NCT06261281

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation therapy
Description: Including:Acupuncture: Regular acupuncture treatment that can prevent muscle atrophy, improve circulation, and have a stimulating effect. Exercise therapy: Training that focused on limb movements or joint mobilization to prevent muscle contracture, reduce joint mobility, improve spasms, and promote blood circulation. Others: Regular turning, back patting, and position changes performed by caregivers.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: Including:Acupuncture: Regular acupuncture treatment that can prevent muscle atrophy, improve circulation, and have a stimulating effect. Exercise therapy: Training that focused on limb movements or joint mobilization to prevent muscle contracture, reduce joint mobility, improve spasms, and promote blood circulation. Others: Regular turning, back patting, and position changes performed by caregivers.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-esophageal Tube Feeding
Description: Based on this, the patients in the observation group were given nutrition support with Intermittent Oro-esophageal Tube Feeding (Medical Device No. 20010234, developed by the Swallowing Disorders Research Institute of Zhengzhou University). The entire feeding process strictly followed the standard procedure of Intermittent Oro-esophageal Tube Feeding. During the feeding process, patients were maintained in a semi-recumbent position with their head elevated, facilitating the placement of the tube into the oral cavity along one side, with the chin brought close to the manubrium sterni.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric tube feeding
Description: The patients in the control group were provided nutrition support with Nasogastric tube feeding, while the feeding process strictly followed the relevant guideline. During the treatment, the patients remained in a continuous state of tube indwelling, receiving feeding every 2-3 hours with a maximum feeding volume of 200ml, of which the contents were consistent with the observation group. The entire feeding process was conducted by trained nursing staff. Besides, the tube was replaced by a new one every 5-7 days.
Study: NCT06164821

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: luspatercept
Description: Adult patients with TD thalassemia were given luspatercept subcutaneous injection.
Study: NCT04908943

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RENEW
Description: RENEW is a 12-week, peer-led, web-based program to help people with scleroderma learn skills that can be used to manage disease symptoms and improve well-being.
Study: NCT05535205

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Digital preoperative assessment
Description: a digital preoperative assessment for patient requiring surgery

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Face-to-face preoperative assessment
Description: a face-to-face preoperative assessment for patient requiring surgery
Study: NCT04879147

Intervention type: DIAGNOSTIC_TEST
Intervention: Evalution of thyroid function
Description: Determination of TSH, free T4, free T3, SPINA-GT, SPINA-GD and Jostel's TSH index

Intervention type: DIAGNOSTIC_TEST
Intervention: Evalution of thyroid function
Description: Determination of TSH, free T4, free T3, SPINA-GT, SPINA-GD and Jostel's TSH index
Study: NCT05613712

Intervention type: OTHER
Intervention: Patients
Description: Description by the patients through the questionnaire of the elements limiting the good ambulatory follow-up

Intervention type: OTHER
Intervention: Referring physician
Description: Description by the referring physicians through the questionnaire of the elements limiting the applicability of the recommendations issued by the rheumatology department of the CHU Grenoble Alpes
Study: NCT06129513

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bilateral resistance exercise
Description: A bout of bilateral resistance exercise consisting of barbell back squat, leg leg press and leg extension

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Bilateral resistance exercise
Description: A bout of bilateral resistance exercise consisting of barbell back squat, leg leg press and leg extension

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Whey protein
Description: Following execution of bilateral resistance exercise, participants will ingest 32 g protein from whey protein isolate

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Plant-blend protein
Description: Following execution of bilateral resistance exercise, participants will ingest 32 g protein from plant-blend protein isolate
Study: NCT06080724

Intervention type: DRUG
Group type: OTHER
Intervention: Comparison of intralesional injection of bleomycin alone and combined with injection dexamethasone
Description: already described

Intervention type: DRUG
Group type: OTHER
Intervention: Comparison of intralesional injection of bleomycin alone and combined with injection dexamethasone
Description: already described
Study: NCT02254915

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Synergo + MMC
Description: Synergo radiofrequency (RF)-Induced hyperthermia-chemotherapy with mitomycin C (RITE). Intravesical instillation of MMC utilizing the Synergo system.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bacillus Calmette-Guérin
Description: Intravesical instillation of BCG.
Study: NCT04880005

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Clinical decision support
Description: Based on the phenotyping and algorithms developed by the hospital specialists at Odense University Hospital and Holbæk Hospital in collaboration with GPs, the individual GPs and their patients will receive individualized recommendations on lifestyle interventions and pharmacological treatments.~The GPs will receive specific clinical decision support (CDS) recommendations on what drugs to prescribe to each patient based on the phenotyping in accordance with a clinical decision support tool (Cambio) and the updated guidelines at all times (Sparrow 2019). The treatment advice to the GPs will be adjusted annually based on treatment effect, re-phenotyping, and updated knowledge of the treatment of T2D. Furthermore, psychiatric, socioeconomic and/or cultural challenges and other determinants for frailty will be a part of the individualized intervention provided to patients by the GPs, again based on the specialist advice.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Lifestyle Coaching
Description: As part of DICTA, the patients are offered a personal health coach (dietician, nurse, occupational therapist, or physiotherapist) through the complex eHealth intervention (Liva). Patients will receive personalized empathic, relation driven coaching on healthy lifestyle on the individual patient's preferences (e.g. increased physical activity, healthier diet, weight loss, smoking cessation, personal goal setting, tailored information, peer to peer support), including optimal pharmacological treatment (Komkova 2019). The collaborative eHealth tool will give health coaches access to patient registered outcome measurements (PRO), information. This forms the basis of the individual coaching and is partly supported by artificial intelligence (AI) to improve the coaching by the health coaches (Holzinger 2016).
Study: NCT06517979

Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence (AI)-based diagnostic model
Description: Collect pathological slides of resected lymph nodes of the enrolled patients. Digitise these slides into whole-slide images (WSIs). Analyze the WSIs using the AI model to generate diagnostic results (with or without lymphatic metastasis). No intervention to patients would be performed in this diagnostic test study.
Study: NCT04880005

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integration to Standard Electronic Health Record
Description: Data on physical activity, steps, diet goal fulfillment, smoking status etc., are being provided for GPs in a web-based solution integrated into the GPs' health record system. Integration with the GP system XMO (covering 52% of all Danish GPs) has been finalized.
Study: NCT04937010

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Occipital nerve stimulator implant
Description: Implantation of occipital nerve stimulator and different stimulation parameters

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Occipital nerve stimulator implant
Description: Implantation of occipital nerve stimulator and different stimulation parameters
Study: NCT05123560

Intervention type: OTHER
Intervention: Anonymous online questionnaire
Description: A QR code qill be provided to access the online questionnaire
Study: NCT04657432

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.
Study: NCT04671472

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NPC-09
Description: The drug will be administered by the oral route with the same manner

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: NPC-09 placebo
Description: The drug will be administered by the oral route with the same manner
Study: NCT04657432

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: MagVenture MagPro TMS System would be utilized to deliver 3-minute sessions of intermittent theta burst to left dorsolateral prefrontal cortex.
Study: NCT05598658

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Remote ischemic conditioning
Description: Remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of healthy upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 200 mm Hg.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Sham remote ischemic conditioning
Description: Sham remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of healthy upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 60 mm Hg.
Study: NCT05833594

Intervention type: DIETARY_SUPPLEMENT
Intervention: Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs
Description: The Experimental group received a combination of omega-3 fatty acids, and glutamine, whereas the control group received standard formula.

Intervention type: DIETARY_SUPPLEMENT
Intervention: Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs
Description: The Experimental group received a combination of omega-3 fatty acids, and glutamine, whereas the control group received standard formula.
Study: NCT05828641

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Supination-flexion maneuver
Description: In the Supination-flexion group, the forearm will be supinated first, followed by full flexion of the elbow joint (Supination-flexion maneuver).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hyperpronation maneuver
Description: In the hyperpronation group, the forearm will be pronated with the child's palm facing down (hyperpronation maneuver).
Study: NCT04792502

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mosunetuzumab
Description: Administered subcutaneously by injection beginning with 5 mg and increasing to 45 mg.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Patients in the augmentation cohort will be dosed continuously, 10 mg orally once daily, with or without food.
Study: NCT05726214

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The face-to-face multicomponent program entailed:~* Strength training of upper and lower limbs. Familiarization phase included 2-3 exercises of 1-2 series and 8-12 repetitions per session. During the acquisition phase, 2-3 exercises of 2-3 series and 8-12 repetitions at a higher velocity. The resting time between sets lasted 1-3 minutes.~* Balance exercises included proprioception, agility and weight transfer exercises. Difficulty progressively increased by reducing the base of support, by including multidirectional displacements, walking on tiptoe or heels, body-weight transfer, dynamic exercises modifying the centre of gravity, and stressing postural muscles and by sensorial reductions.~* Flexibility exercises: Static stretching maintained during 20-30s carried out at the end of each session.~The Vivifrail exercise wheel corresponding to each participant was given according to their functional level type.

Intervention type: OTHER
Group type: OTHER
Intervention: Recommendations for active lifestyle
Description: After the baseline assessments, all participants received individualized counseling for following physically active lifestyle and reducing sedentary behaviors. Participants were encouraged to increase the physical activity time and intensity, and to hourly break the sedentary time while at home. The recommendations were transmitted verbally and through written material.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Recommendations for active lifestyle
Description: After the baseline assessments, all participants received individualized counseling for following physically active lifestyle and reducing sedentary behaviors. Participants were encouraged to increase the physical activity time and intensity, and to hourly break the sedentary time while at home. The recommendations were transmitted verbally and through written material.
Study: NCT04755374

Intervention type: OTHER
Intervention: Discharged ≤ 21 days
Description: Discharged from palliative care unit in equal less than 21 days

Intervention type: OTHER
Intervention: Prolonged discharge
Description: Discharged from palliative care unit in longer than 21 days
Study: NCT04928183

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Carbon monoxide rebreathe
Description: Carbon monoxide exposure to increase blood (Carboxyhemoglobin) COHb safely to \~10%

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Nitroprusside
Description: Bolus Sodium Nitroprusside (SNP) injection for endothelium-independent vasodilation measure

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Sodium Nitroprusside
Description: Bolus Sodium Nitroprusside (SNP) injection for endothelium-independent vasodilation measure

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenylephrine Hydrochloride
Description: Bolus Phenylephrine injection for observe α1-mediated vasoconstriction during mild exercise

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Phenylephrine Hydrochloride
Description: Bolus Phenylephrine injection for observe α1-mediated vasoconstriction during mild exercise
Study: NCT05594784

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olverembatinib
Description: a third-generation TKI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: a selective inhibitor of B-cell lymphoma 2 (Bcl-2)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: prednisone
Description: Glucocorticoids

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Anti-tumor alkaloids
Study: NCT06364280

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BVM
Description: Bag-Valve-Mask Ventilation

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BVM
Description: Bag-Valve-Mask Ventilation

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BVM
Description: Bag-Valve-Mask Ventilation

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SGA
Description: Supraglottic Airway

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ETI
Description: Endotracheal Intubation