TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05272982

Intervention type: DIAGNOSTIC_TEST
Intervention: Thoracic fluid content by electrical cardiometry group
Description: Thoracic fluid content will be measured using electrical cardiometry device (ICON ® Cardiotronics, Inc., La Jolla, CA 92307; Osyka Medical GmbH, Berlin, and Germany, model C3, Serial no: 1725303). The ICON device will be connected to four electrocardiogram electrodes which will be placed over patients' skin after cleaning with alcohol at the neck below the left ear, just above the left clavicular midpoint, and two electrodes at left mid-axillary line one at the level of the xiphoid process, and the other electrode 5 cm below this point. The thoracic fluid content will be observed for 30 s and the average of the highest and lowest values will be recorded.

Intervention type: DIAGNOSTIC_TEST
Intervention: Thoracic fluid content by electrical cardiometry group
Description: Thoracic fluid content will be measured using electrical cardiometry device (ICON ® Cardiotronics, Inc., La Jolla, CA 92307; Osyka Medical GmbH, Berlin, and Germany, model C3, Serial no: 1725303). The ICON device will be connected to four electrocardiogram electrodes which will be placed over patients' skin after cleaning with alcohol at the neck below the left ear, just above the left clavicular midpoint, and two electrodes at left mid-axillary line one at the level of the xiphoid process, and the other electrode 5 cm below this point. The thoracic fluid content will be observed for 30 s and the average of the highest and lowest values will be recorded.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound examination group
Description: The 12-region technique for lung assessment will be performed using Philips ® (CX50 - Extreme edition) equipped with phased array transducer. B-line will be defined as laser like vertical hyperechoic artefact which extends between the pleural line and the bottom of the screen and moves with respiratory movements. Two types of B-lines will be evaluated.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound examination group
Description: The 12-region technique for lung assessment will be performed using Philips ® (CX50 - Extreme edition) equipped with phased array transducer. B-line will be defined as laser like vertical hyperechoic artefact which extends between the pleural line and the bottom of the screen and moves with respiratory movements. Two types of B-lines will be evaluated.
Study: NCT05873465

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sedation with Midazolam, Fentanyl, and Propofol
Description: Patients will have teeth extracted under sedation with Midazolam, Fentanyl, and Propofol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sedation with Midazolam, Fentanyl, and Propofol
Description: Patients will have teeth extracted under sedation with Midazolam, Fentanyl, and Propofol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sedation with Midazolam, Fentanyl, and Propofol
Description: Patients will have teeth extracted under sedation with Midazolam, Fentanyl, and Propofol

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extraction of teeth
Description: The necessary teeth will be extracted

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extraction of teeth
Description: The necessary teeth will be extracted

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extraction of teeth
Description: The necessary teeth will be extracted
Study: NCT05121883

Intervention type: DRUG
Intervention: Edaravone Dexborneol
Description: Edaravone dexborneol (Jiangsu Simcere Pharmaceutical, Co, Ltd) will be initiated within 48 hours of stoke onset at 37.5 mg/dose, once every 12 hours, and continuing for more than 7 days (maximum: 14 days)
Study: NCT05090111

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALG-055009
Description: Single or multiple doses of ALG-055009

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single or multiple doses of Placebo
Study: NCT06381947

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lipid-lowering therapy combination with PCSK9 inhibitors, bempedoic acid and ezetimibe
Description: Evaluation of therapy of bempedoic acid with PCSK9 inhibitors and ezetimibe in reducing LDL-C in statin-intolerant patients.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lipid-lowering therapy combination with PCSK9 inhibitors and ezetimibe
Description: Evaluation of therapy of PCSK9 inhibitors with ezetimibe in reducing LDL-C in statin-intolerant patients.
Study: NCT06448520

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Power Sprint Test
Description: The Muscle Power Sprint Test (MPST) is an easy-to-perform field test of anaerobic capacity for children and adolescents. The only necessities for the administration of this test are an open space, a stopwatch and two cones or lines. Test subjects are encouraged to perform six 15-meter sprints at a maximal pace between the two cones/lines, with a 10-second rest in between each effort. The distance covered during these short runs corresponds well to the distances children cover during daily play activities. The power that is generated with each sprint can be calculated using the formula: power = (total mass x 15 m²)/time³.
Study: NCT05524376

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT06329245

Intervention type: OTHER
Intervention: Do not take any interventions
Description: Do not take any interventions

Intervention type: OTHER
Intervention: Do not take any interventions
Description: Do not take any interventions
Study: NCT05913895

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: hydrogen water
Description: To investigate whether the intervention of hydrogen water adjuvant therapy can improve oral mucositis, oral frailty, pain and Quality of Life with head and neck cancer who have received radiation therapy or combined chemotherapy.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hydrogen water
Description: To investigate whether the intervention of hydrogen water adjuvant therapy can improve oral mucositis, oral frailty, pain and Quality of Life with head and neck cancer who have received radiation therapy or combined chemotherapy.
Study: NCT05830474

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continuous intra-airway monitoring and intervention during surgey
Description: Continuous monitoring was performed by visual double lumen bronchial catheter. Once sputum or blood gushing into the tracheal carina was found in the distal bronchus on the surgical side, the above secretions were sucked out with a sputum suction tube under video monitoring until the removal was complete
Study: NCT04997512

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Freestyle libre
Description: A glucose sensor (flash) which measures interstitial blood glucose every 15 minutes or on demand.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nurse led structured intervention - hypoglycaemia education and diabetes treatment modification modification
Description: An education programme surrounding avoidance of hypoglycaemia at baseline. Regular review (weeks 2, 4, 12 and 24) and adjustment of diabetes medications based on freestyle libre data.
Study: NCT05804539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: The therapist checks the range of motion of the cervical joints and gives manual treatment to the restricted joints. Throughout the examination, the subject lied in a supine position on a professional rehabilitation bed with the seventh cervical vertebra (C7) on the edge of the bed and the other the body above the C7 were placed off the bed. The therapist held the subject's occipital bone with one hand and the radial aspect of the second metacarpophalangeal joint of the other hand to grip the spinous process of the sixth cervical vertebra and slowly pushed the occiput downward to check the joint mobility of the fifth cervical vertebra and the sixth cervical vertebra. After the examination, the restricted joint was accurately located and treated with targeted manual therapy. For example, stretching was performed with the right side of C4-C5 flexed, closing only the right side of the subject's C4-C5 as much as possible to increase joint mobility on the right side of C4-C5.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi
Description: Based on the characteristics of young people and the need to correct their FHP, the classic Yang's 24 Forms of Tai Chi has been improved. The movements are mostly upper limb movements and the lower limb movements have been simplified to make the movements easy to learn. The modified Tai Chi exercise retains the traditional Tai Chi movements but is simple and easy to learn; at the same time, it increases the movement of the shoulder and neck joints. The subjects performed each exercise session in a group setting at the school gymnasium, with a professional Tai Chi instructor guiding them through a warm-up session, followed by a Tai Chi exercise session.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi and Manual therapy
Description: Intervention content of MSG included 15-min Tai Chi exercise and 15-min manual therapy, with the order of intervention being Tai Chi exercise first and then manual therapy.
Study: NCT05000034

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Weaning protocol
Description: Application of a weaning protocol from the mechanical ventilation
Study: NCT05534620

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: IV infusion
Study: NCT05882461

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 90Second Caregiver health letter
Description: Participant receives the weekly health letter via email
Study: NCT04956133

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Participants will receive the IMPACT program, which includes a combination of aerobic, resistance, balance, and flexibility exercises conducted 1:1 and delivered online by a physical activity specialist via Zoom. The IMPACT program follows basic physical activity progression principles (i.e., principles of frequency, intensity, time, type, overload and progression). Tailoring will be used to promote fitness and wellness benefits, while ensuring safety. In addition, prominent behaviour change techniques will be provided by physical activity specialists within each 1:1 session. Discussions and worksheets will be provided, depending on participants needs.
Study: NCT06081478

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD19/CD22-bispecific CAR-T cells
Description: CD19/CD22-bispecific CAR-T cells were infused at the same day with 2×10e6/kg and 1×10e6/kg dosage, respectively.
Study: NCT05962073

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HFNC
Description: High-flow oxygen therapy before intubation for preoxygenation
Study: NCT05737108

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Bilberry capsule product
Description: A specific bilberry capsule product, containing bilberry dried extracts at 23.2 mg and bilberry powder at 3.2 mg will be given to participants for oral intake for 30 days. 30 days of Bilberry capsule product or placebo with crossover to the other.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bilberry capsule product
Description: A specific bilberry capsule product, containing bilberry dried extracts at 23.2 mg and bilberry powder at 3.2 mg will be given to participants for oral intake for 30 days. 30 days of Bilberry capsule product or placebo with crossover to the other.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo(starch)
Description: 30 days of placebo or Bilberry capsule product with crossover to the other.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo(starch)
Description: 30 days of placebo or Bilberry capsule product with crossover to the other.
Study: NCT06432023

Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance imaging
Description: Diagnostic and research scanning using magnetic resonance imaging.

Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance imaging
Description: Diagnostic and research scanning using magnetic resonance imaging.
Study: NCT05030792

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Attention-restorative therapy (ART)-based virtual reality (VR)
Description: The ART-based VR intervention will be provided using an Oculus Go™ which is a commercially available, all-in-one VR headset with a handheld controller.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Attention-restorative therapy (ART)-based virtual reality (VR)
Description: The ART-based VR intervention will be provided using an Oculus Go™ which is a commercially available, all-in-one VR headset with a handheld controller.
Study: NCT06202742

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive behavioral therapy for insomnia
Description: Online meeting, weekly for 8 weeks, to deliver CBTI by psychologist/ psychiatrist

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health education
Description: Online meeting, weekly for 8 weeks, to deliver general health knowledge
Study: NCT05394675

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-9606a
Description: Intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-9606a
Description: Intravenous infusion
Study: NCT05658900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enucleation with albumin PRF
Description: The protocol that will be used in the preparation of albumin PRF~1. A sample of venous blood, at ten milliliters, at least will be drawn from the patient in a sterile centrifuge tube.~2. The venous blood sample will be centrifuged at 700 g for 8 minutes.~   \* Betadine: Povidone-iodine, 7.5% (0.75% available iodine), Purdue Products L.P~3. The platelet-poor plasma layer will be taken and heated at uniform temperature 75 celsius for 10 minutes in a thermostatic water bath incubator to denature albumin protein forming albumin gel.~4. Once the albumin gel is cooled, to room temperature for 10 minutes, it will be mixed with the buffy coat layer of PRF using 3 way stop cock and 2 plastic syringes with Luer lock to obtain albumin PRF then leave it in the dappen dish for 5 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Enucleation without albumin PRF
Description: The full-thickness mucoperiosteal flap will be performed using blade no. 15 and Bard- Parker handles extending one tooth anterior and one tooth posterior to the cystic cavity.~The mucoperiosteal flap will be reflected using the periosteal elevator to expose the bone.~Removal of the overlying bone to expose the cystic lesion. Enucleation of the cyst.
Study: NCT06404736

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bispecific antibody (bsAb) targeting PD-1 and CLTA-4
Description: QL1706 is a novel bispecific combination antibody composed of a recombinant humanized IgG4 monoclonal antibody targeting human PD-1 (programmed cell death protein 1) (PSB103) and a recombinant humanized IgG1 monoclonal antibody targeting human CTLA-4 (cytotoxic T-lymphocyte-associated protein 4) (PSB105). Both antibodies have undergone engineering modifications to introduce mutations facilitating their correct assembly and preventing mispairing, and are expressed in the same cell line at a predetermined ratio (approximately 2:1).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin-bound paclitaxel
Description: Albumin-bound paclitaxel improves the solubility and delivery of paclitaxel to tumor cells by binding to human albumin, facilitating its transportation through the bloodstream and enhancing its uptake into tumor tissue. It works by binding to and stabilizing microtubules within cancer cells, thereby disrupting the normal process of cell division and leading to cell cycle arrest and apoptosis, ultimately resulting in the death of cancer cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin is a chemotherapy medication belonging to the platinum-based class of drugs, commonly used in the treatment of various cancers, including ovarian cancer, lung cancer, and bladder cancer. It functions by forming DNA adducts, disrupting DNA replication and transcription processes in cancer cells, ultimately leading to cell death. Despite its efficacy, carboplatin can cause side effects such as nausea, vomiting, and bone marrow suppression.
Study: NCT06498323

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: tenecteplase
Description: Intravenous thrombolytic agents administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tenecteplase
Description: Intravenous thrombolytic agents administration
Study: NCT05407168

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Receive standard of care
Study: NCT05689684

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: AG+XOS+AXOS
Description: 4-month parallel randomized controlled study

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Maltodextrin
Description: 4-month parallel randomized controlled study
Study: NCT05407168

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Promotion and Education
Description: View decision aid

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT06157008

Intervention type: DRUG
Intervention: General Anesthetics
Description: General anesthetics used in spinal cord electrical stimulator insertion surgery
Study: NCT05342766

Intervention type: DIETARY_SUPPLEMENT
Intervention: Nutrigenetic
Description: Each grup will receive two interventions (Nutrigenetic and Standard), in a cross-over design (3 months each), spaced by a wash-out period (3 months).

Intervention type: DIETARY_SUPPLEMENT
Intervention: Nutrigenetic
Description: Each grup will receive two interventions (Nutrigenetic and Standard), in a cross-over design (3 months each), spaced by a wash-out period (3 months).
Study: NCT05747183

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ProTaper Ultimate
Description: Root canal preparation using ProTaper Ultimate files.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ProTaper Gold
Description: Root canal preparation using ProTaper Gold files.
Study: NCT04951583

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: FMT + ICI
Description: This study will include 3 cohorts of patients: (1) Patients with advanced or unresectable NSCLC, (2) patients with advanced or unresectable melanoma, and (3) patients with unresectable or advanced uveal melanoma. Patients with NSCLC, melanoma, uveal melanoma and will be analyzed in three separate subgroups given their differing clinical outcomes.~Each group will be treated with ICI as per their respective first line options, in combination with investigational FMT capsules.
Study: NCT06583265

Intervention type: DRUG
Intervention: Observational
Description: To observe if endometrial compaction ≥ 5% in down regulated FET cycles increases clinical pregnancy rate.
Study: NCT06584201

Intervention type: PROCEDURE
Intervention: Erector Spinae Plane Block (ESP)
Description: The ESP block will be administered before the VATS procedure, aiming to manage postoperative pain and minimize the impact on early lung function test (SFT) parameters. The block will be performed using standard techniques under ultrasound guidance to ensure accurate placement.

Intervention type: PROCEDURE
Intervention: Paravertebral Block (PVB)
Description: The PVB will be administered prior to the VATS procedure, with the objective of managing postoperative pain and assessing its impact on early postoperative lung function (SFT) parameters. This block will also be performed using standard techniques and ultrasound guidance for precision.
Study: NCT06549426

Intervention type: DRUG
Group type: OTHER
Intervention: anti-seizure medication + sedative agent(s)
Description: Stepwise approach:~1. a single dose of a parenteral benzodiazepine (lorazepam, midazolam, or diazepam) and a first parenteral anti-seizure medication (levetiracetam, valproate, or lacosamide)~2. a second parenteral anti-seizure medication plus a first continuous parenteral sedative agent (midazolam or propofol)~3. a second continuous parenteral sedative agent (midazolam, propofol, or ketamine)
Study: NCT05122091

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib + SOX
Description: Fruquintinib：5mg qd for 2 weeks on and 1 week off, q3w； SOX: Tegafur gimeracil oteracil potassium capsule: 40-60mg bid（dosage according to body surface area），d1-14，q3w； Oxaliplatin：130mg/m2，intravenous (IV) ，d1，q3w.
Study: NCT06392243

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intracardiac ultrasound imaging system
Description: The control group was treated with SOUNDSTAR 3D Diagnostic Ultrasound catheter (SNDSTR10G) and Vivid IQ, intracardiac and macrovascular imaging of the heart, assessment of intracardiac Doppler flow, and guidance for intracardiac intervention

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intracardiac ultrasound imaging system
Description: The control group was treated with SOUNDSTAR 3D Diagnostic Ultrasound catheter (SNDSTR10G) and Vivid IQ, intracardiac and macrovascular imaging of the heart, assessment of intracardiac Doppler flow, and guidance for intracardiac intervention
Study: NCT04040829

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive remediation therapy (CR)
Description: Cognitive remediation therapy is a behavioral intervention that aims to improve cognition. This intervention has the goal to produce long-term improvements in cognition as well as to generalize these improvements in daily functioning.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supported education (SE)
Description: Supported education (SE) is a behavioral intervention that aims to help people return to school and/or succeed in school. SE offers a wide range of services that are personalized to the needs of each patients.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Supported education (SE)
Description: Supported education (SE) is a behavioral intervention that aims to help people return to school and/or succeed in school. SE offers a wide range of services that are personalized to the needs of each patients.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as usual (TAU)
Description: Treatment as usual (TAU) consists of medication and routine contact with the clinical team.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual (TAU)
Description: Treatment as usual (TAU) consists of medication and routine contact with the clinical team.
Study: NCT04279522

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Relivion®DP- Active
Description: Relivion®DP- Active stimulation device

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Relivion®DP- Sham
Description: Relivion®DP- Sham stimulation device