TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05007587

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mFOLFOX regimen
Description: HAIC was performed every 3 weeks. The mFOLFOX regimen was administered via hepatic artery: oxaliplatin , 85mg/m2 , from hour 0 to 2 on day1 ; leucovorin , 400mg/m2 , from hour 2 to 3 on day 1 ; fluorouracil , 400mg/m2 , bolus at hour 3 ; and 2400mg/m2 over 46 hours on days 1 and 2.3mg/m2 , from hour 4 to 5 on day 1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ROX regimen
Description: HAIC was performed every 3 weeks. The ROX regimen was administered via hepatic artery: oxaliplatin , 100mg/m2 , from hour 0 to 4 on day1 ;raltitrexed , 3mg/m2 , from hour 4 to 5 on day 1.
Study: NCT06114030

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Deep margin elevation with composite resin and Lithium disilicate glass-ceramic crowns
Description: Restoration of the deep margin by composite restorations such as: Filtek Supreme XTE, Tetric EvoCeram, Estelite Sigma Qquick followed by Lithium disilicate glass-ceramic CAD/CAM crowns (IPS e.max CAD).
Study: NCT04716478

Intervention type: OTHER
Intervention: Clinical and radiological data collection
Description: No specific intervention. Data of the usual care will be collected as the demographic data, the medical history, imaging report, etc.
Study: NCT06156891

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Toxicities reduced treatment
Description: Two cycles toripalimab+docetaxel+cisplatin+capecitabine (TPF) induction chemotherapy followed by reducing radiation dose(60Gy/30Fx) and omitting concurrent cisplatin chemotherapy when responses to induction chemotherapy are ≥ 70% Partial Response(PR) in HPV-related patients.~Two cycles toripalimab+docetaxel+cisplatin+capecitabine (TPF) induction chemotherapy followed by reducing radiation dose(60Gy/30Fx) combined with concurrent cisplatin chemotherapy when responses to induction chemotherapy are ≥ 70% Partial Response(PR) in HPV-urelated patients.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Two cycles toripalimab+docetaxel+cisplatin+capecitabine (TPF) induction chemotherapy followed by concurrent cisplatin chemoradiotherapy with standard radiation dose (70.4Gy/32Fx) when responses to induction chemotherapy are less than 70% Partial Response (PR) regardless of HPV status.
Study: NCT05946707

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: restrictive oxygen supply
Description: Oxygen supply will be limited to guarantee normoxia at the beginning of OLV.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: liberal oxygen supply
Description: Oxygen supply will be maximized to 100% at the beginning of OLV
Study: NCT05444413

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ultrasound-guided platelet rich plasma nerve block
Description: selected persons are treated by ultrasound-guided platelet rich plasma nerve block and the regular medicine
Study: NCT05110599

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bryophyllum 50% chewable tablets
Description: Each 350 mg tablet corresponds to 170 mg of leave press juice from Bryophyllum pinnatum, dried down to 17 mg by mixing with lactose; 100 mg dried BP matter in 1 g

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Lactose with adaption in appearance and tast
Study: NCT05718661

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Watching video with virtual glasses
Description: Using Mobile Virtual Glasses; In the preoperative period, after the patient is taken to the surgical service, a virtual reality video will be watched with mobile virtual glasses at the specified time (before going to the operating room on the day of surgery). Measurements will be made before and after the application. Necessary hygiene will be provided before the use of glasses, and the researcher will ensure hand cleaning before entering the patient's room.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: watching video without virtual glasses
Description: The plain version of the video, which was shown to the intervention group by the researcher (SŞ) to the placebo group, will be watched over the phone with the naked eye and the stress level on the smart bracelet will be recorded.
Study: NCT05340491

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: 240mg, D1, every 3 weeks per cycle, three cycles with chemotherapy and eight cycles after IMRT

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: Gemcitabine: 1.0g/m2, D1 and D8, Cisplatin 80mg/m2, D1, every 3 weeks per cycle, total three cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Gemcitabine: 1.0g/m2, D1 and D8, Cisplatin 80mg/m2, D1, every 3 weeks per cycle, total three cycles

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Intensity modulated radiotherapy
Description: total 60-66Gy, 1.8-2.0Gy/f/day

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity modulated radiotherapy
Description: total 60-66Gy, 1.8-2.0Gy/f/day
Study: NCT06075862

Intervention type: PROCEDURE
Intervention: Decompressive surgery
Description: Decompressive lumbar spinal surgery
Study: NCT04896541

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 300 mg IM(male)
Description: Single dose of 300 mg of AZD7442 or saline placebo on Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 300 mg IM(male)
Description: Single dose of 300 mg of AZD7442 or saline placebo on Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 600 mg IM (male)
Description: Single dose of 600 mg of AZD7442 or saline placebo on Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 600 mg IM (male)
Description: Single dose of 600 mg of AZD7442 or saline placebo on Day 1.
Study: NCT06231875

Intervention type: DEVICE
Intervention: Press
Description: Fabrication of clear aligners using press machine (Mini-star)
Study: NCT04896541

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 300 mg IV (male and female)
Description: Single dose of 300 mg of AZD7442 or saline placebo on Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 300 mg IV (male and female)
Description: Single dose of 300 mg of AZD7442 or saline placebo on Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 1000 mg IV (male)
Description: Single dose 1000 mg of AZD7442 or saline placebo on Day 1.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AZD7442 1000 mg IV (male)
Description: Single dose 1000 mg of AZD7442 or saline placebo on Day 1.
Study: NCT04303104

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: GeneXpert Edge
Description: Screening intervention: novel diagnostic for Active Case Finding (GeneXpert MTB/RIF) for TB on sputum collected and performed at point-of-contact in a mobile van

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: GeneXpert Ultra
Description: Screening intervention: novel diagnostic test for Active Case Finding (GeneXpert MTB/RIF) for TB on sputum collected at point-of-contact in a mobile van but sent to laboratory
Study: NCT05332665

Intervention type: DEVICE
Intervention: AS-OCT
Description: Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.

Intervention type: DEVICE
Intervention: AS-OCT
Description: Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.
Study: NCT04779307

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.
Study: NCT05332665

Intervention type: DEVICE
Intervention: AS-OCT
Description: Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.

Intervention type: PROCEDURE
Intervention: YAG laser PI
Description: medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block

Intervention type: PROCEDURE
Intervention: YAG laser PI
Description: medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block
Study: NCT05054920

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: concentric exercises
Description: concentric exercises for rotator cuff. internal rotators, external rotators and abductors Patient will do 3 sets of 10 repetitions resistance will be personalized to each patients

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eccentric exercises
Description: Eccentric exercises exercises for rotator cuff internal rotators, external rotators and abductors Patient will do 3 sets of 10 repetitions resistance will be personalized to each patients

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stretching
Description: stretching exercise for posterior capsule and pectoralis minor each stretch will be done for 30 seconds and repeated 3 times

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stretching
Description: stretching exercise for posterior capsule and pectoralis minor each stretch will be done for 30 seconds and repeated 3 times
Study: NCT04863677

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training(HIIT）
Description: Last 12 weeks (3 sessions per week)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate Intensity Continuous Training(MICT）
Description: Moderate Intensity Continuous Training(MICT）
Study: NCT05477316

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation treatment
Description: Radiation treatment of IMRT to the cerebellum and SRS to the cerebrum
Study: NCT05625646

Intervention type: OTHER
Intervention: quality assurance program
Description: The program consists of an online quiz using a multiple choice questionnaire (MCQ) design. The participants are expected to complete the online MCQ at 3, 6, 9, and 12 months following baseline. The MCQ includes still-pictures and video sequences of the 10 application specific POCUS examinations from the course curriculum. Through 15-20 questions, the quiz tests the OSAUS dimentions Each question has four possible answers of which up to three answers are correct. Each MCQ will have ten questions pertaining to pathologies within the ten applications of the curriculum. Further, there will be five to ten questions relating to image recognition, image optimisation, ultrasound artifacts. Once each MCQ is finalized, the participating GP's will receive feed-back on the answers with suggestions for improvement and guidance toward continuing self-directed learning.
Study: NCT05410197

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envofolimab
Description: 400mg by subcutaneous injection every 3 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 8 mg orally once a day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: 1000mg/m2 by intravenous infusions on day 1 and 8 every 3 weeks for up to 24 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: 25mg/m2 by intravenous infusions on day 1 and 8 every 3 weeks for up to 24 weeks
Study: NCT05739240

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Osteosynthesis
Description: Osteosynthesis of distal radius fractures

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Osteosynthesis
Description: Osteosynthesis of distal radius fractures
Study: NCT04511988

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diagnostic Test
Description: blood sample (20 ml) and biopsy
Study: NCT04779307

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab IV infusion.
Study: NCT05954949

Intervention type: PROCEDURE
Intervention: Adenomas detection rate with the different observation methods
Description: Films performed in white light high definition, NBI and indigo-carmine dye, will be compared blindly to detecte number of adenomas with the different observation methods
Study: NCT05865301

Intervention type: OTHER
Intervention: Questionnaire for patients receiving therapy
Description: Questionnaires will be given (at baseline, 1, 3, 6, and 12 months post CAR infusion) including baseline demographics, individual/family and neighborhood socioeconomic data, measures of household material hardship (housing and transportation insecurity, household energy and food insecurity), barriers to care at the CAR T cell institution, as well as patient reported outcomes following Kymriah infusion.

Intervention type: OTHER
Intervention: Questionnaire for patients receiving therapy
Description: Questionnaires will be given (at baseline, 1, 3, 6, and 12 months post CAR infusion) including baseline demographics, individual/family and neighborhood socioeconomic data, measures of household material hardship (housing and transportation insecurity, household energy and food insecurity), barriers to care at the CAR T cell institution, as well as patient reported outcomes following Kymriah infusion.
Study: NCT05332665

Intervention type: PROCEDURE
Intervention: YAG laser PI
Description: medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block
Study: NCT05711706

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Su Jok Application
Description: Su Jok massage appplication
Study: NCT06442904

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital education program
Description: The approximately six hours long digital education program will be available for three months and implies further education in intraoral radiographic examinations.
Study: NCT04063891

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-magnitude high-frequency vibration (LMHFV)
Description: Low-magnitude high-frequency vibration (LMHFV) is a biophysical intervention that provides non-invasive, systemic mechanical stimulation and has been reported to have no adverse effect.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Low-magnitude high-frequency vibration (LMHFV)
Description: Placebo group will have sham treatment by standing on the LMHFV platform for 20 minutes/day
Study: NCT06257446

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Task Instructions
Description: Participants will be given cued instructions as to whether they are in a high or low motivation condition
Study: NCT05318300

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: tested formula with fiber
Description: formula containing fibers

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: formula without fiber
Study: NCT05354492

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Program to Support Well-Being after Adversity
Description: You will be asked to meet on Zoom weekly for 6 weeks with our trained program facilitators along with the other 6-10 members of the intervention group. Meetings will last approximately 75-90 minutes each, and will involve a variety of discussions and activities related to navigating the changes you may face after experiencing a difficult life event. These sessions will be audio-recorded for research purposes and to ensure that facilitators are doing a good job delivering the program.
Study: NCT05674227

Intervention type: PROCEDURE
Intervention: Robotic surgery
Description: Surgical treatment of operable lung cancers using robotic systems

Intervention type: PROCEDURE
Intervention: Video-assisted thoracoscopy
Description: Surgical treatment of operable lung cancers using a video-assisted thoracoscopy approach (VAT)

Intervention type: PROCEDURE
Intervention: Open surgery
Description: Surgical treatment of operable lung cancers using open surgery
Study: NCT06472323

Intervention type: PROCEDURE
Intervention: PRF+PRP, PRF
Description: Under CT guidance, the trocar then was inserted through the ipsilateral foramen ovale to the Gasserian ganglion of the patient. After puncturing the foramen ovalis, remove the cannula needle core and connected with RF electrode (PMK-21-100, Baylis, Canada) and the RF generator. Electrical stimulation was carried out at 50 Hz to determine the sensory threshold and at 2 Hz to determine the motor threshold. The RF generator was set to the manual PRF mode with a standard setting of 42°C, the UP knob was turned to increase the output voltage until the maximum voltage (bearable without causing pain in conscious patients)was reached; 120 s, 2 times. After removing the RF electrode in the combined treatment group, 2ml of LP-PRP mixture was injected slowly into the Gasserian ganglion and mandibular nerve and PRF group only receive PRF treatment.

Intervention type: PROCEDURE
Intervention: PRF+PRP, PRF
Description: Under CT guidance, the trocar then was inserted through the ipsilateral foramen ovale to the Gasserian ganglion of the patient. After puncturing the foramen ovalis, remove the cannula needle core and connected with RF electrode (PMK-21-100, Baylis, Canada) and the RF generator. Electrical stimulation was carried out at 50 Hz to determine the sensory threshold and at 2 Hz to determine the motor threshold. The RF generator was set to the manual PRF mode with a standard setting of 42°C, the UP knob was turned to increase the output voltage until the maximum voltage (bearable without causing pain in conscious patients)was reached; 120 s, 2 times. After removing the RF electrode in the combined treatment group, 2ml of LP-PRP mixture was injected slowly into the Gasserian ganglion and mandibular nerve and PRF group only receive PRF treatment.
Study: NCT06291311

Intervention type: OTHER
Intervention: Cold physical Plasma
Description: The treatment is administered by either the supervising specialists or assistant doctors at the University Women's Hospital, under their supervision and authorization. It's important to note that the NIPP treatment is designed to be relatively brief, with a duration not exceeding 10-20 minutes.

Intervention type: OTHER
Intervention: Control group
Description: A potential natural healing of the HPV infection will be anticipated
Study: NCT05646225

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chest physiotherapy and early mobilization
Description: Chest Physiotherapy: Each session included a series of exercises, lasting a total of 15 minutes and including positioning self-conscious breathing control, diaphragmatic breathing control, and exercises for the chest wall and abdominal muscle walls.~Early mobilization: Each session included abdominal and upper and lower limb exercises, shoulder and full arm circling, lying to sit, sit to stand, walk and other exercises. This training has been described previously and used in other clinical trials. Each exercise was repeated 8-10 times over 30 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: early mobilization
Description: Each session included abdominal and upper and lower limb exercises, shoulder and full arm circling, lying to sit, sit to stand, walk and other exercises. This training has been described previously and used in other clinical trials. Each exercise was repeated 8-10 times over 30 minutes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: early mobilization
Description: Each session included abdominal and upper and lower limb exercises, shoulder and full arm circling, lying to sit, sit to stand, walk and other exercises. This training has been described previously and used in other clinical trials. Each exercise was repeated 8-10 times over 30 minutes
Study: NCT04742777

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rapamycin
Description: Taken orally 1mg daily for 8 weeks
Study: NCT05448729

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Elastography EUS
Description: Comparison between the values of strain ratio and shear wave in concordance with the final diagnosis

Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Elastography EUS
Description: Comparison between the values of strain ratio and shear wave in concordance with the final diagnosis
Study: NCT05400850

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: YOGA
Description: Five different YOGA Asana's will made randomly
Study: NCT06374004

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Group
Description: The exercises will be given as a home program and each exercise will be performed 2 times a day for a total of 12 weeks. Participants will perform the exercises 1 day a week under the supervision of a physiotherapist. The exercise program lasts approximately 30 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Group
Description: The exercises will be given as a home program and each exercise will be performed 2 times a day for a total of 12 weeks. Participants will perform the exercises 1 day a week under the supervision of a physiotherapist. The exercise program lasts approximately 30 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic Mobilization Group
Description: The exercises will be given as a home program and each exercise will be performed 2 times a day for a total of 12 weeks. Participants will perform the exercises 1 day a week under the supervision of a physiotherapist. The exercise program lasts approximately 30 minutes. Thoracic mobilization will be applied to segments where passive accessory movement is insufficient or painful. 30 repetitions/4 sets will be applied to each determined segment. Thoracic mobilization will be performed with the patient lying prone position.
Study: NCT05535764

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegylated interferon alpha2a
Description: PegINFa will be given once every 2 weeks by subcutaneous administration in the abdomen or thigh.