TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05119374

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SenseGuard Investigational Device
Description: SG is a wireless, wearable medical device, which includes nano-based sensors. It can seamlessly measure patient's tidal breathing during daily activities. SG extracts series of critical respiratory parameters, including; Respiration Rate (RR), Inhalation and Exhalation duration and ratio (I/E), as well as novel biomarkers. SG parameters are applicable to evaluate COPD patients' condition, or for monitoring patients with other respiratory conditions.~SG components are:~* RSM (Respiratory Sensing Module): non-invasive module with sensors that can detect the exhaled humidity and condensation. The RSM is a non-sterile, disposable, single patient use.~* ECU (Electronic Control Unit): a re-usable, wireless data acquisition and transmission unit. The ECU is connected to the RSM during the measurement and transmits the data via Bluetooth to the SG software.~* SenseGuard™ Software: for data management, acquisition, processing, logging and presentation of the digital respiratory signals.
Study: NCT06379503

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HEART YOGA
Description: Heart yoga; It includes regular, balanced, safe light physical exercises, breathing exercises that provide breathing control, and meditation practices that include relaxation techniques.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: routine nursing care
Description: Basic nursing care after heart surgery
Study: NCT05165004

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kangaroo Mother Care
Description: the preterm neonate was carefully put naked except for the head and diaper area on the mothers' bare chest with flexed arms and legs as in froglike position, and the head was turned sideways. The researchers wrapped and secured the mother's gown and put a blanket on the neonates' back to ensure neonatal thermal insulation

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hammock Positioning
Description: After one hour of feeding, the preterm neonate was placed in a supine fetal position in the hammock where the head was supported in a neutral midline position by using rolled towel without neck hyperflexion or hyperextension. Moreover, the spine of the preterm neonate was supported while arms and knees were flexed

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine Care of NICU
Description: ; encircling the neonate in a fetal position using rolled towel inside the incubator.
Study: NCT03398252

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxazosin XL
Description: Participants will be randomized to receive increasing doses of doxazosin XL (0, 4, and 8 mg).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be randomized to receive a placebo for doxazosin XL.
Study: NCT06463249

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Extended Helpline
Description: Those who achieved 2% weight loss at 2-month, will continue to Extended Helpline, where the participants can continue receiving all CORE resources including1-on-1 coaching through 1 optional participant-initiated call per month for 6 months.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Helpline
Description: Those who do not reach 2% weight loss at the end of 2 months will be randomized. Participants will continue to receive all CORE resources plus 1 optional participant-initiated call/month for 6 months. Additionally, the participants will receive 2 individualized coach-scripted feedback emails per month, and the option to receive daily text message reminders.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive Helpline
Description: Those who do not reach 2% weight loss at the end of 2 months will be randomized. Participants will continue to receive all CORE resources plus 2 scheduled coaching calls/month for 6 months. Additionally, the participants will receive 2 individual coach-scripted feedback emails per month, and the option to receive daily text message reminders.
Study: NCT05519124

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-785-7
Description: Treatment with the BTL-785-7 applicator to the BTL-785F system.
Study: NCT05002036

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Trium eyedrops
Description: given three times daily from day 1 after surgery to end of Week 4
Study: NCT05135468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CU-40102 Spray
Description: topical application, 1\~4 sprays each time, once daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CU-40102 Spray
Description: topical application, 1\~4 sprays each time, once daily
Study: NCT05046236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interactive POWER rehabilitation
Description: Interactive POWER rehabilitation training for twice a week, total 12 weeks, that consisted of 6 types of equipment for strength training.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventical physical training
Description: Conventional physical training models in current clinical use for twice a week, total 12 weeks, that consisted of strength training, balance training, stretching, gait training, and etc.
Study: NCT04247321

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Licox® Brain Tissue Oxygen Monitoring System
Description: Invasive brain tissue oxygenation monitoring

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-infrared spectroscopy (NIRS)
Description: Non-invasive approach to monitoring brain tissue oxygenation which uses two wavelengths of near infrared light and takes measurements of the ratio of oxyhemoglobin to total hemoglobin
Study: NCT06353867

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group Exercise
Description: The children with special needs included in the study were included in group exercises for 45 minutes 2 days a week in groups of 10 children each. Group exercises were planned as balance and coordination exercises including warm-up and cool-down periods. In the warm-up and cool-down periods, counting in place and balance exercises were performed. The exercises included tasks such as side walking, tandem walking, walking on a balance board, walking in a figure 8, walking over obstacles, throwing a ball to the person next to him/her while passing through cones, and throwing a ball by jumping while passing through cones.The exercises were made more difficult by following a progressive method every 2 weeks. The exercises were performed in 3 sets of 5 repetitions under the supervision of a physiotherapist.
Study: NCT05724147

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mandala Activity
Description: Three sessions of mandala activity, once a week, will be applied to the participants from the elderly people in the nursing home included in the study. The mandala activity planned to be done with the group will be done in addition to the standard monitoring applied in the institution, so it will be held at an appropriate time according to the flow in the institution. Before leaving the individuals, the most appropriate time for the next mandala session will be determined by taking into account the preferences of the individuals. Individuals to be included in the study will be grouped in groups of 10. Mandala activity application time is planned to last approximately 2 hours. If individuals have any physical symptoms, the time of the mandala activity is rescheduled, and each individual is expected to attend five sessions during the total study period.
Study: NCT05678504

Intervention type: DEVICE
Intervention: The phlebotomy procedure
Description: The process of blood collection with a vascular imaging device
Study: NCT06070727

Intervention type: OTHER
Group type: OTHER
Intervention: Obturator
Description: Evaluation of patient satisfaction and oral healthy related quality of life of Polyetherketoneketone(PEKK) and metal framework for management of maxillectomy cases.

Intervention type: OTHER
Group type: OTHER
Intervention: Obturator
Description: Evaluation of patient satisfaction and oral healthy related quality of life of Polyetherketoneketone(PEKK) and metal framework for management of maxillectomy cases.
Study: NCT05151562

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Music Therapy
Description: Each study participant will receive two 30-minute live synchronous virtual music therapy sessions per week for a period of 8 weeks to be delivered by a board-certified music therapist (using Zoom as a primary platform). These individualized therapeutic encounters will use music that is personally meaningful and familiar to the participant and the participant's loved ones to facilitate reminiscence. Decision-making processes made by the music therapist will reflect a flexible session structure and series of intervention choices contingent on each participant's cultural identity, expressive and receptive communication, fine and gross motor ability, affect, orientation to time and place, and personal preferences on any given day.
Study: NCT04703335

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antimicrobial efficacy of gel ZHCK4 as a patient preoperative skin preparation
Description: Evaluate the antimicrobial efficacy of two concentrations of one patient preoperative skin preparation product compared to a positive control (2.0% chlorhexidine gluconate) and negative control (physiological saline 0.9% solution). Following a 14-day restriction period, subjects will be sampled for baseline, 10-minutes, 6-hours, and 24-hours microbial reduction evaluations post-product application. Subjects will not be sequestered for the 6-hour or 24-hour evaluations. Test day baseline criteria will be set at: abdomen: ≥ 3.0 log10 CFU/cm2, and inguen: ≥ 5.0 log10 CFU/cm2.
Study: NCT05854082

Intervention type: DRUG
Group type: OTHER
Intervention: Lidocaine 2% Polyampoule
Description: Three intervention conditions in a repeated measures design - lidocaine; no perturbation, candy (lollipop)
Study: NCT05535270

Intervention type: DIAGNOSTIC_TEST
Intervention: Oxford Depression Questionnaire (ODQ)
Description: The Oxford Depression Questionnaire (ODQ)is a patient-centered questionnaire. The scale contains three sections: i) the patient's experience in the past week; ii) the patient's experience before the illness worsened, and iii) the patient's emotional feelings about receiving antidepressant treatment. The 26-item questionnaire contains four dimensions of emotional blunting: not caring (NC), emotional detachment from others (ED), reduction in positive emotions (RP), and general reduction in emotions (GR). Patients not taking antidepressants were only required to rate the first two sections .

Intervention type: DIAGNOSTIC_TEST
Intervention: Oxford Depression Questionnaire (ODQ)
Description: The Oxford Depression Questionnaire (ODQ)is a patient-centered questionnaire. The scale contains three sections: i) the patient's experience in the past week; ii) the patient's experience before the illness worsened, and iii) the patient's emotional feelings about receiving antidepressant treatment. The 26-item questionnaire contains four dimensions of emotional blunting: not caring (NC), emotional detachment from others (ED), reduction in positive emotions (RP), and general reduction in emotions (GR). Patients not taking antidepressants were only required to rate the first two sections .
Study: NCT04626570

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive and Behavioral Therapy
Description: 12 sessions of CBT using a standardized approach
Study: NCT05575583

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: repetitive transcranial magnetic stimulation
Description: The neural navigation system was used to accurately locate the stimulus target.Continuous theta short rapid pulse mode was used. CTBS mode consisted of a slave stimulus delivered every 0.2 seconds (5Hz), and each slave stimulus consisted of three bursts of 50Hz. A single stimulus lasts about 40 seconds and totals 600 pulses.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: pseudo repetitive transcranial magnetic stimulation
Description: Participant in control group receive pseudo repetitive transcranial magnetic stimulation
Study: NCT06322108

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botensilimab + Balstilimab
Description: Botensilimab is a fragment crystallizable (Fc)-engineered human immunoglobulin G1 (IgG1) monoclonal antibody that targets cytotoxic T lymphocyte-associated protein 4 (CTLA-4). Balstilimab is a human monoclonal antibody that targets programmed cell death protein 1 (PD-1).
Study: NCT05371275

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Description: 125 mg of palbociclib once daily for 21 consecutive days
Study: NCT05813860

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Azathioprine
Description: azathioprine in combination with Infliximab, with a dose of 1-2 mg/kg/d.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Infliximab
Description: 5mg/kg for the first dose, and the same dose at weeks 2 and 6 after the first dose and every 8 weeks thereafter. Treatment with single Infliximab or combined azathioprine, respectively.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Infliximab
Description: 5mg/kg for the first dose, and the same dose at weeks 2 and 6 after the first dose and every 8 weeks thereafter. Treatment with single Infliximab or combined azathioprine, respectively.
Study: NCT04743869

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kyphos FS™ Bone Substitute
Description: Dorsal instrumentation via Longitude II (Medtronic Austria GmbH/Vienna) and balloon kyphoplasty are performed. KyphOs FS™ bone cement will be introduced in the fractured vertebral body.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: KYPHON ActivOs® Bone Cement with Hydroxyapatite
Description: Dorsal instrumentation via Longitude II (Medtronic Austria GmbH/Vienna) and balloon kyphoplasty are performed. KYPHON ActivOs® Bone Cement with Hydroxyapatite will be introduced in the fractured vertebral body.
Study: NCT05762965

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: GOS 1
Description: 1 sachet each morning

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: GOS 2
Description: 1 sachet each morning
Study: NCT04800575

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: semi-permeable film
Description: Experiment group use semi-permeable film as dressing in exit-site of CVC and dressings will be changed per hemodialysis session, or or whenever the dressing is soiled, bloody, or fell off.

Intervention type: DEVICE
Group type: OTHER
Intervention: sterile gauze and tape
Description: Control group use sterile gauze and tape as dressing in exit-site of CVC and dressings will be changed per hemodialysis session, or whenever the dressing is soiled, bloody, or fell off.
Study: NCT06200597

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LAD603
Description: LAD603 SC injection.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo SC injection.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo SC injection.
Study: NCT05319886

Intervention type: DRUG
Intervention: Anlotinib and Penpulimab
Description: Anlotinib 12mg, po, qd, with 2 weeks off for 1 week. Penpulimab 200mg, ivgtt, q3w. Efficacy was evaluated every 2 cycles. Efficacy evaluation was performed every 2 cycles during the follow-up study. Patients with disease control (CR+PR+SD) and tolerable adverse reactions continued to take the drug until the investigator considered that the patient was not suitable to continue the drug or the efficacy was evaluated as PD. Safety evaluations were performed concurrently with the dosing period. No other antitumor therapy can be administered until PD.
Study: NCT03683095

Intervention type: PROCEDURE
Intervention: Lymphovenous bypass
Description: Lymphovenous bypass will be performed under general anesthetic. Indocyanine green lymphangiography will be performed by injecting indocyanine green into each finger / toe web of the lymphedematous limb and mapping the lymphatic system with the NOVADAQ SPY Fluorescence Imaging (Mississauga, Canada).~Subdermal dissection of lymphatics and venules will be carried out under a surgical microscope. Lymphatic vessels will be anastomosed to adjacent recipient venules to create the bypass between the lymphatic and the venous systems. In total, 1-5 anastomoses will be performed. This will require 1-5 incisions, each with a length of 2-3 cm.~Postoperatively, the limb will be wrapped loosely with compression bandages. No special postoperative monitoring is required.~The surgery will be performed on an outpatient basis with no planned hospital stay.
Study: NCT06243289

Intervention type: OTHER
Intervention: Tolerance induction
Description: Exposure of peripheral blood mononuclear cells extracted from donated patient blood to a combination of vitamin D3 and interleukin 10 to test whether tolerogenic dendritic cells can be generated and have the same functional capacity between donors with and without kidney disease (exposure of PBMC to the uremic environment)

Intervention type: OTHER
Intervention: Tolerance induction
Description: Exposure of peripheral blood mononuclear cells extracted from donated patient blood to a combination of vitamin D3 and interleukin 10 to test whether tolerogenic dendritic cells can be generated and have the same functional capacity between donors with and without kidney disease (exposure of PBMC to the uremic environment)
Study: NCT06019091

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Compass Health TENS 3000, 3 mode Analog Unit
Description: The TENS unit Compass Health TENS 3000, 3 mode Analog Unit will be configured based on randomization to 20 Hz, 50 Hz, or 100 Hz. Pulse width 200 microseconds, Normal (N) Mode. It will be used on the posterior tibial nerve via a patch that is supplied each day for 30 minutes of the day. These 30 minutes of intervention will occur at the participants most painful time of the day for their pain.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Compass Health TENS 3000, 3 mode Analog Unit
Description: The TENS unit Compass Health TENS 3000, 3 mode Analog Unit will be configured based on randomization to 20 Hz, 50 Hz, or 100 Hz. Pulse width 200 microseconds, Normal (N) Mode. It will be used on the posterior tibial nerve via a patch that is supplied each day for 30 minutes of the day. These 30 minutes of intervention will occur at the participants most painful time of the day for their pain.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Compass Health TENS 3000, 3 mode Analog Unit
Description: The TENS unit Compass Health TENS 3000, 3 mode Analog Unit will be configured based on randomization to 20 Hz, 50 Hz, or 100 Hz. Pulse width 200 microseconds, Normal (N) Mode. It will be used on the posterior tibial nerve via a patch that is supplied each day for 30 minutes of the day. These 30 minutes of intervention will occur at the participants most painful time of the day for their pain.
Study: NCT06218628

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talazoparib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talazoparib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talazoparib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talazoparib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talazoparib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pacritinib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pacritinib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pacritinib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pacritinib
Description: pacritinib in combination with talazoparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pacritinib
Description: pacritinib in combination with talazoparib
Study: NCT04686929

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abatacept s.c.
Description: subcutaneous abatacept: 250mg (d-1) , 125mg (d+5, +14, +21, +28, +35, +42, +49, +56) combined with CsA, MTX, MMF.
Study: NCT06009406

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy
Description: This group will be applied to the soleus, gastrocnemius muscle and Achilles tendon with Graston, an instrumental myofascial mobilization technique, until they feel warmth in the skin and tonus relaxation in the target muscles. The control group will be subjected to 3 repetitions of passive stretching for 30 seconds for the same structures.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy
Description: This group will be applied to the soleus, gastrocnemius muscle and Achilles tendon with Graston, an instrumental myofascial mobilization technique, until they feel warmth in the skin and tonus relaxation in the target muscles. The control group will be subjected to 3 repetitions of passive stretching for 30 seconds for the same structures.
Study: NCT05390034

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ART
Description: Session 1: Description of the group \& Psychoeducation Session 2: Breathing and muscle relaxation Session 3: Importance of practice/motivation Session 4: Nonjudgemental awareness Session 5: Acceptance and tolerance Session 6: Self-support Session 7: Analysis of emotions Session 8: Modification of emotions Session 9: Practice and contextual applications + end of group

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Relaxation
Description: Session 1: Description of the groupe \& Psychoeducation Session 2: Breathing control 1 Session 3: Breathing control 2 Session 4: Muscle relaxation Session 5: Visualisation Session 6: Stretching Session 7: Schultz relaxation Session 8: Schultz relaxation Session 9: Summary and end of group