TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06032091

Intervention type: OTHER
Intervention: No intervention
Description: The study is observational and will not include any specific interventions other than the regular care practice that the participants receive from their care providers. The study will use a wrist-mounted smartwatch for monitoring. Previous studies show acceptability toward wearable devices among persons with dementia; however, if the care staff recognize discomfort or distress caused by the device, it will be immediately removed.
Study: NCT06152432

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary implant overdenture
Description: Patients with an edentulous maxilla and problems with their conventional denture are treated with an implant overdenture either retained by bars or Locators

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary implant overdenture
Description: Patients with an edentulous maxilla and problems with their conventional denture are treated with an implant overdenture either retained by bars or Locators
Study: NCT05866757

Intervention type: OTHER
Group type: OTHER
Intervention: Discontinuation of maintenance treatment
Description: The discontinuation of maintenance treatment in multiple myeloma. Classed as interventional due to treatment being taken away.
Study: NCT05332912

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Spatial Ability Experience
Description: Participants will engage in puzzle construction, block play, visual search, hide and seek

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Spatial Ability Experience
Description: Participants will engage in puzzle construction, block play, visual search, hide and seek
Study: NCT05784129

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Guselkumab
Description: Guselkumab will be administered subcutaneously.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered subcutaneously.
Study: NCT05743712

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SMART-Wrap
Description: This intervention, SMS (short message system)-based augmentation, seeks to improve the impact and approach of the Wraparound service model by utilizing SMS, which has been shown to increase treatment adherence and sustained engagement. This intervention will facilitate regular, repeated evaluation of intermediate outcomes through self-report assessments.
Study: NCT06269458

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baby Massage
Description: In the baby massage application, mothers were trained on baby massage and the massage applied by the mother to her baby was observed once. The baby massage video prepared by the researchers was shared with mothers. Mothers were informed about the importan

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Monther-Baby Yoga
Description: Mothers were asked to choose the most suitable time of day for themselves and the baby, to ensure that the baby was fed at least 45 minutes before yoga, and to practice yoga in a calm and dimly lit environment, listening to music or white noise of their choice. One yoga session lasted approximately 20 minutes. Mothers and their babies did mother-baby yoga three times a week for four weeks. Mothers were informed about the importance of having the same treatment room for each treatment. All mothers were called once a week by a researcher to provide counseling and follow-up of the process.~At the end of four weeks, measurement tools were applied to all mothers and the groups were changed, massage was applied to the yoga group, and yoga intervention was applied to the massage group, as in the beginning of the research. At the end of four weeks, all mothers were evaluated for mother-infant attachment and the infant's sleep diary.
Study: NCT05775978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Más Presente, the UGRComp program
Description: Más Presente, the UGRComp program is based upon the European LifeComp framework (Sala, Punie, Garkov and Cabrera Giraldez 2020) and covers intra and interpersonal, emotional, cognitive and metacognitive aspects. Created at the University of Granada by an interdisciplinary group of experts, it focuses on three core elements (self-regulation, empathy and growth mindset) as they are the pre-requisites for developing all other elements across framework areas. It consists of 8 weekly classes, 2 hours each, together with a day of intensive practice. The program is structured along the following topics: The Underpinnings of Más Presente; Awareness and Concentration: our Body; Managing our Emotional Laberynth; Walking with Directionality, Sense and Conscience; Empathy, Presence and Connection; Empathic Listening and Honest Expression: Non-violent communication; Growth Mindset, Creativity and Divergent Thinking; And Now what? The First Day of the Rest of My Life.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The MBSR program
Description: The MBSR program is a group-based therapy which teaches mindfulness skills through a range of formal and informal mindfulness practices. Created by Kabat-Zinn (1982), in the current study it is taught by an officially accredited instructor and is compliant with the guidelines established by Brown University and the University of Massachusetts, USA. It originally consists of 8 weekly classes, 2 hours each (18 hours direct instruction), together with a day of intensive practice. The program is structured along the following topics: The Underpinnings of MBSR; The Perception of Reality; Power in Being Present; Understanding Stress: The Mind-Body Relation; Responding to Stress; Communication and Personal Relations; Daily Life Management; My Personal Plan: What lies ahead.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Neuro-muscular stimulation
Description: Subjects will receive weekly sessions with a combination of educational sessions and specific physical exercises to enhance physical wellbeing and prevent neuro-degeneration . After spotting the therapeutic targets for each subject, a 4-phase program will be designed for each subject aimed at improving lifestyle habits and general wellbeing.
Study: NCT04797676

Intervention type: PROCEDURE
Intervention: different methods of specimen acquisition
Description: After informed consent, the investigators use two methods to obtain specimens for patients with pancreatic ductal adenocarcinoma, who needs eus-fnb for auxiliary diagnosis and had the opportunity of surgery. One method is EUS-FNB with wet suction technique, the other is surgery (including radical operation and cytoreductive surgery). Both methods are used on the same patient to remove deviations in results caused by tumor heterogeneity.

Intervention type: PROCEDURE
Intervention: different methods of specimen acquisition
Description: After informed consent, the investigators use two methods to obtain specimens for patients with pancreatic ductal adenocarcinoma, who needs eus-fnb for auxiliary diagnosis and had the opportunity of surgery. One method is EUS-FNB with wet suction technique, the other is surgery (including radical operation and cytoreductive surgery). Both methods are used on the same patient to remove deviations in results caused by tumor heterogeneity.
Study: NCT05883124

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivastigmine twice-weekly 9,5 mg/24 h
Description: 3 consecutive applications of 1 patch (1st patch for 4 days, 2nd patch for 3 days, 3rd patch for 4 days) covering an 11-day period

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exelon® 9.5 mg/24 h
Description: 11 consecutive applications of 1 patch (each patch will be applied for 1 day) covering an 11-day period
Study: NCT04977323

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TICK-B group
Description: These interventions will use as distraction techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TICK-B group
Description: These interventions will use as distraction techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TICK-B group
Description: These interventions will use as distraction techniques.
Study: NCT05420402

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol bolus
Description: A bolus dose of propofol 1 mg/kg was administered intravenously at 3 minutes before the end of the surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol continuous infusion
Description: 1 mg/kg propofol was started by continuous infusion 3 minutes before the end of surgery, and the infusion time was 3 minutes.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol bolus
Description: A bolus dose of propofol 1 mg/kg was administered intravenously at the end of the surgery.
Study: NCT05596760

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Jumpstart Guide
Description: The Jumpstart Guide is a communication-priming intervention for clinicians, patients and their families in the outpatient setting. The intervention's goal is to prompt clinicians to provide, during a scheduled (non-urgent) clinic visit, standard of care which includes a discussion with patients (and/or their LNOKs) about their goals of care. It is designed to promote and guide these discussions for older adults with memory problems through suggestions and tips on the Jumpstart Guide.
Study: NCT01614028

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Total Hip Arthoplasty

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Total Hip Arthoplasty
Study: NCT05715567

Intervention type: OTHER
Intervention: Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (NCT03374800)
Description: Following the intervention of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (NCT03374800)

Intervention type: OTHER
Intervention: Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (NCT03374800)
Description: Following the intervention of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (NCT03374800)
Study: NCT06200675

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Compassion-based intervention
Description: Participants assigned to this intervention will be asked to engage in one brief compassion-focused exercise, where they will be asked to be asked to connect to their inner compassionate self. They will be asked to stay connected to that feeling while rereading what they wrote about their feelings of shame and imagining it was someone else who wrote it. Participants will then be asked to write a compassionate response to themselves. Participants will then be asked to reread this response while remaining connected to their compassionate self.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Logic-based intervention
Description: Participants assigned to this intervention will be asked to engage in one brief (10-15 minute) online logic-based exercise that was adapted from a CBT thought record. Participants will be asked to reread what they wrote about their feelings of shame and chose a thought central to their shame to use for this exercise. Participants will be asked to generate evidence for and against their chosen thought, and then generate a more balanced thought. After the exercise, participants will be asked to reread their newly generated more balanced thought.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo control condition
Description: Participants assigned to this intervention will be asked to listen to an audio recording of The Hobbit and then re-read what they wrote about their feelings of shame. They will then be asked to write a reflection about the thoughts and feelings arising from doing so. They will then be asked to re-read what they wrote in this reflection.
Study: NCT05788458

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: The blocks will be performed in supine position under complete aseptic condition. The site to be blocked will be painted with 5% povidone iodine followed by 70% ethyl alcohol and draped. Linear high-frequency ultrasound probe (7 -15 mhz) (General Electric; GE, LOGIQ E) will be initially placed in a transverse plane over the anterior superior iliac spine (ASIS) and then alignes to identify the following landmarks: Anterior inferior iliac spine, ilio-pubic eminence, iliopsoas muscle and tendon, the femoral artery, and Pectineus muscle. Point of injection will be musculo-fascial plane between the psoas tendon and ilio-pubic eminence.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: The blocks will be performed in supine position under complete aseptic condition. The site to be blocked will be painted with 5% povidone iodine followed by 70% ethyl alcohol and draped. Linear high-frequency ultrasound probe (7 -15 mhz) (General Electric; GE, LOGIQ E) will be initially placed in a transverse plane over the anterior superior iliac spine (ASIS) and then alignes to identify the following landmarks: Anterior inferior iliac spine, ilio-pubic eminence, iliopsoas muscle and tendon, the femoral artery, and Pectineus muscle. Point of injection will be musculo-fascial plane between the psoas tendon and ilio-pubic eminence.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: The blocks will be performed in supine position under complete aseptic condition. The site to be blocked will be painted with 5% povidone iodine followed by 70% ethyl alcohol and draped. Linear high-frequency ultrasound probe (7 -15 mhz) (General Electric; GE, LOGIQ E) will be initially placed in a transverse plane over the anterior superior iliac spine (ASIS) and then alignes to identify the following landmarks: Anterior inferior iliac spine, ilio-pubic eminence, iliopsoas muscle and tendon, the femoral artery, and Pectineus muscle. Point of injection will be musculo-fascial plane between the psoas tendon and ilio-pubic eminence.
Study: NCT04797260

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Gene therapy
Description: Patients will be infused with autologous CD34+ cells transduced with the pCCL.MND.coRAG1.wpre lentiviral vector (RAG1 LV CD34+ cells).
Study: NCT06482008

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hepatic arterial infusion chemotherapy(HAIC) combined with adebrelimab plus apatinib
Description: HAIC every 3 weeks until 6 treatments have been completed, or HAIC therapy is terminated if patients have not reached 6 treatments and experience intolerable adverse effects; adebrelimab, fixed dose 1200 mg, IV, D1, every 21 days (Q3W), in combination with apatinib, 250 mg (0.25 g), orally, once daily (QD), consecutively dosing in 3-week (21-day) treatment cycles. Study treatment will continue until the subject develops an intolerable toxic reaction, withdraws informed consent, and progresses according to RECIST v1.1 as confirmed by the investigator (after the subject develops disease progression as defined by RECIST v1.1, if the investigator assesses that the subject is still clinically beneficial and can tolerate the study treatment, the subject may continue to receive the study drug; if it is considered that the subject no longer has clinical benefit, then treatment may be terminated), or other termination criteria specified in the protocol, whichever occurs first.
Study: NCT05936866

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic floor stretching
Description: Week 1 to 4: Pelvic floor muscles awareness, Breathing exercises , seated pelvic tilts, cat stretches, seated hip openers (2 sets, 8 reps, sustained for 6 seconds) Week 5 to 8: Pelvic floor muscles awareness, Breathing exercises ,seated pelvic tilts, cat stretches, Seated hip openers, Relaxed Frog (2 sets, 8 reps, sustained for 6 seconds) Week 9 to 13: Pelvic floor muscles awareness, Breathing exercises, seated pelvic tilts, cat stretches, Seated hip openers, Relaxed Frog side lying clamshells, mini squats with support (2 sets, 9 reps, sustained for 7 seconds)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor strengthening
Description: Week 1 to 4: Pelvic floor muscles awareness, Breathing exercises, 2 Sets of 10 Reps for pelvic floor squeeze and release Seated marching with elastic band with pelvic floor squeeze.~Week 5 to 8: 2 sets x 9 Reps for Pelvic floor squeeze and release, Seated marching with elastic band with pelvic. 2 Sets x 8 Reps for bridging with pelvic floor squeeze, side lying hip circles Week 9 to 13: 2 sets 10 reps for Pelvic floor squeeze-and-release, Seated marching with elastic band with pelvic floor squeeze, pelvic bridging with pelvic floor squeeze, side lying hip circles with pelvic floor squeeze. 2 sets, 8 reps for . side lying Clamshells with resistance band and pelvic floor squeeze and plie squats with pelvic floor squeeze
Study: NCT05832489

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate immediate release 25mg
Description: Patients will have 2 imaging sessions (MRI and EEG) after either:~* methylphenidate immediate release 25 mg~* placebo~in a cross-over design. The two imaging sessions will be separated by 11 to 87 days.
Study: NCT05274490

Intervention type: PROCEDURE
Intervention: intubation and mechanical ventilation
Description: patients who were in need were intubated and mechanically ventilated

Intervention type: PROCEDURE
Intervention: intubation and mechanical ventilation
Description: patients who were in need were intubated and mechanically ventilated
Study: NCT04889742

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: loco-regional hyperthermia
Description: loco-regional hyperthermia by the use of microwave, capacitive, or superficial hyperthermia devices.
Study: NCT05137873

Intervention type: OTHER
Intervention: Dunn-2 infant Sensory Profile (PS2-N)
Description: The Dunn-2 infant Sensory Profile evaluates the child's sensory integration process
Study: NCT06496165

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam
Description: Intravenous pump injection. The loading dose will be 0.1mg/kg, the maintenance dose will be 0.1-0.5mg/kg/h, with the target RASS be -2-0
Study: NCT05188859

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab+Anlotinib+Pemetrexed+Cisplatin
Description: Sintilimab 200mg+Anlotinib 12mg+Pemetrexed 500mg/m²+Cisplatin 75mg/m2
Study: NCT06496165

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Intravenous pump injection. The loading dose will be 0.5mg/kg, the maintenance dose will be 1-4mg/kg/h, with the target RASS be -2-0
Study: NCT05246709

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cyanoacrylate glue
Description: Adhesive to be applied on the PICC line site prior to usual standard film dressing over the site, such as SecurePortIV® Catheter Securement Adhesive by Adhezion Biomedical® Cyanoacrylate adhesive that is FDA-approved for securement of vascular access devices.~Securement method that provides microbial protection by sealing the insertion site.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard transparent film dressing
Description: A standard transparent polyurethane film dressing, such as 3M TEGADERM Film, for dressing the PICC line area.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard transparent film dressing
Description: A standard transparent polyurethane film dressing, such as 3M TEGADERM Film, for dressing the PICC line area.
Study: NCT04921904

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: 150mg dose administered orally twice daily every day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ramucirumab
Description: 8mg/kg iv every 2 weeks until evidence of disease
Study: NCT06040762

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Receive SOC educational materials

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Intervention
Description: Receive (P)REHAB exercise program

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App-Based Intervention
Description: Use ExerciseRx app

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App-Based Intervention
Description: Use FitBit app

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: App-Based Intervention
Description: Use FitBit app

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wearable Activity Tracker
Description: Wear FitBit

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Wearable Activity Tracker
Description: Wear FitBit

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical Performance Testing
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Performance Testing
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT04734301

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intravaginal Electrical Stimulation (2 times/week)
Description: IVES sessions were performed two times in a week, for 10 weeks. Every session lasted 20 minutes. The intervention comprised a 20-sessions treatment program of ES. The stimulation parameters were frequency at 10 Hz, a 5-10s work-rest cycle and 100 ms pulse width. The symmetric biphasic pulse wave could be delivered over a range of 0-100 mA. The intensity was controlled according to patients' discomfort level feedback.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intravaginal Electrical Stimulation (5 times/week)
Description: IVES performed in the same way as Group 1, except for frequency of treatment. IVES sessions were performed five times in a week, for 4 weeks. Every session lasted 20 minutes. The intervention comprised a 20-sessions treatment program of ES. Stimulation parameters were the same as Group 1.
Study: NCT05209373

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention Condition
Description: 4-week intervention combining behaviour change and self-compassion education to promote coping with CVD risk and increased engagement in physical activity.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Positive Control Condition
Description: 4-week intervention combining behaviour change and self-compassion education to promote coping with CVD risk and increased engagement in physical activity.
Study: NCT05665803

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pediatric rotary files
Description: Mechanical preparation of primary tooth canals with pediatric rotary files

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Manual flare files
Description: Mechanical preparation of primary tooth canals with manual flare files
Study: NCT05505864

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Action Process Approach (HAPA)
Description: Health Action Process Approach (HAPA) using action planning and coping strategies to create health behaviour change