TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04796935

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tactile Imaging (VerTouch)
Description: VerTouch device used to identify and mark, or begin placement of a needle at an insertion site. After the device is taken off the back, the procedure will continue in the usual manner.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control (palpation)
Description: Control, palpation used to identify and mark an insertion site.
Study: NCT05651880

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baricitinib 4 MG
Description: 4 mg per day for 6 months (For patients with creatinine clearance between 30 and 60 mL/min at baseline or during the study, the dosage of baricitinib will be 2 mg daily)
Study: NCT06492538

Intervention type: PROCEDURE
Intervention: various types of angle interventions
Description: procedures include laser peripheral iridotomy (LPI) to relieve pupillary tissue and deepen peripheral anterior chamber depth, Argon laser peripheral iridoplasty (ALPIp) to stimulate iris contraction and widen the angle, and mechanical separation of adhered angle tissues using instruments like goniosynechialysis hooks or iris repositor. Ab interno goniotomy using instruments like retina hooks, trabeculectomy hooks, or cannulas are used to incise trabecular meshwork and Schlemm's canal walls to enhance aqueous humor outflow.

Intervention type: PROCEDURE
Intervention: various types of angle interventions
Description: procedures include laser peripheral iridotomy (LPI) to relieve pupillary tissue and deepen peripheral anterior chamber depth, Argon laser peripheral iridoplasty (ALPIp) to stimulate iris contraction and widen the angle, and mechanical separation of adhered angle tissues using instruments like goniosynechialysis hooks or iris repositor. Ab interno goniotomy using instruments like retina hooks, trabeculectomy hooks, or cannulas are used to incise trabecular meshwork and Schlemm's canal walls to enhance aqueous humor outflow.

Intervention type: PROCEDURE
Intervention: various types of angle interventions
Description: procedures include laser peripheral iridotomy (LPI) to relieve pupillary tissue and deepen peripheral anterior chamber depth, Argon laser peripheral iridoplasty (ALPIp) to stimulate iris contraction and widen the angle, and mechanical separation of adhered angle tissues using instruments like goniosynechialysis hooks or iris repositor. Ab interno goniotomy using instruments like retina hooks, trabeculectomy hooks, or cannulas are used to incise trabecular meshwork and Schlemm's canal walls to enhance aqueous humor outflow.

Intervention type: PROCEDURE
Intervention: various types of angle interventions
Description: procedures include laser peripheral iridotomy (LPI) to relieve pupillary tissue and deepen peripheral anterior chamber depth, Argon laser peripheral iridoplasty (ALPIp) to stimulate iris contraction and widen the angle, and mechanical separation of adhered angle tissues using instruments like goniosynechialysis hooks or iris repositor. Ab interno goniotomy using instruments like retina hooks, trabeculectomy hooks, or cannulas are used to incise trabecular meshwork and Schlemm's canal walls to enhance aqueous humor outflow.

Intervention type: PROCEDURE
Intervention: various types of angle interventions
Description: procedures include laser peripheral iridotomy (LPI) to relieve pupillary tissue and deepen peripheral anterior chamber depth, Argon laser peripheral iridoplasty (ALPIp) to stimulate iris contraction and widen the angle, and mechanical separation of adhered angle tissues using instruments like goniosynechialysis hooks or iris repositor. Ab interno goniotomy using instruments like retina hooks, trabeculectomy hooks, or cannulas are used to incise trabecular meshwork and Schlemm's canal walls to enhance aqueous humor outflow.
Study: NCT06518863

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Educational handouts on how to adhere to the corresponding diet.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Educational handouts on how to adhere to the corresponding diet.
Study: NCT06550674

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Constitutional exome analysis
Description: For each patient included:~* A family tree is drawn up, reporting personal and family histories of cancer. The patient's anatomopathological reports, related to his or her tumor lesions, are retrieved, in order to confirm/clarify individual or family diagnoses.~* A blood sample and a jugal smear are taken to enable constitutional genetic exome analysis for research purposes.
Study: NCT05788068

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavior therapy
Description: Participants will receive CBT intervention for smoking cessation via wechat-based mini-program developed by a professional team.
Study: NCT04955743

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200 mg intravenous (IV) is administered every 3 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200 mg intravenous (IV) is administered every 3 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 20 mg orally (PO) is administered daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 20 mg orally (PO) is administered daily
Study: NCT05209568

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gluten Powder
Description: Single oral dose of gluten powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gluten Powder
Description: Single oral dose of gluten powder
Study: NCT06029361

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Selfit Device group
Description: During 21 days, intervention group will receive physical therapy of 45 minutes which 15 minutes out of the 45 minutes will be with the SELFIT system

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: Conventional physical therapy of 45 minute
Study: NCT06102785

Intervention type: DRUG
Intervention: Fruquintinib, TAS102
Description: Fruquintinib combined with TAS102
Study: NCT06523374

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Endoscopic brush cytology
Description: A total of four brush samples will be taken during the endoscopy. Other minimally invasive interventions during this study are standard of care.
Study: NCT06347107

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robotic subretinal tPA injection
Description: -The insertion of a 41G subretinal needle adjacent to a subretinal hemorrhage using the stabilizing (tremor-reducing) properties of a robotic instrument in order to slowly inject tPA and evaluate whether the needle can be held in place for up tot 3 minutes.
Study: NCT05032833

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-MeO-DMT
Description: A single dose of 5-MeO-DMT will be administered intranasally

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A single dose of placebo will be administered intranasally
Study: NCT05310383

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tislelizumab plus radiotherapy
Description: During the period of radiotherapy, patients receiveTislelizumab 200 mg intravenously (IV) on Day 1 of each 3-week cycle (Q3W). Tislelizumab 200mg q3W was administered for up to 35 cycles (up to approximately 2 years) after radiotherapy until disease progression or toxicity.
Study: NCT05986539

Intervention type: OTHER
Intervention: Observational
Description: This study is only observational in nature and will not include an intervention.

Intervention type: OTHER
Intervention: Observational
Description: This study is only observational in nature and will not include an intervention.
Study: NCT05121597

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HugeMed Videolaryngoscope
Description: Macintosh laryngoscope

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HugeMed Videolaryngoscope
Description: Macintosh laryngoscope
Study: NCT04501653

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: Psilocybin is a naturally occurring psychedelic compound produced by psilocybin mushrooms, and has been shown to have antidepressant and anti-anxiety effects after one dose of 25 mg. Common side effects are slight elevations in blood pressure and heart rate. Participants will be randomized to receive either psilocybin or control at two separate imaging timepoints in this study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin is a naturally occurring psychedelic compound produced by psilocybin mushrooms, and has been shown to have antidepressant and anti-anxiety effects after one dose of 25 mg. Common side effects are slight elevations in blood pressure and heart rate. Participants will be randomized to receive either psilocybin or control at two separate imaging timepoints in this study.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylphenidate
Description: Methylphenidate is a stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, and is used as an active control for this study because it is metabolized similarly to psilocybin and has similar effects on heart rate and blood pressure. Participants will be randomized to receive either psilocybin or control at two separate imaging timepoints in this study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate
Description: Methylphenidate is a stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, and is used as an active control for this study because it is metabolized similarly to psilocybin and has similar effects on heart rate and blood pressure. Participants will be randomized to receive either psilocybin or control at two separate imaging timepoints in this study.
Study: NCT05480423

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based intervention
Description: 1. Psychoeducation video on mindfulness and mindful parenting. 2. Audio files of mindfulness exercises including mindfulness of breath, body scan, mindful stretching, mindfulness of soles of the feet, befriending exercises. 3. Informal mindfulness exercises by applying mindfulness in daily lives
Study: NCT06551103

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention group trained in line with the Health Promotion Model
Description: A literature review was conducted by the researchers within the scope of Health Promotion Model and a educational material was prepared. With this educational material, the patients in the intervention group were trained in four sessions lasting 25 minutes each.
Study: NCT06387160

Intervention type: DRUG
Intervention: as per institutional protocol
Description: This is an observational study. Treatment will be given to the patients as per institutional protocol
Study: NCT06066801

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bedside blind bone biopsy procedure
Description: It was performed in the patient's room under aseptic conditions. Pain relievers were given orally within the hour preceding the procedure. Superficial anesthesia was performed firstly subcutaneously and then on the periosteum, Inhaled anesthesia was started concomitantly. Following a short incision with a scalpel, the trocar inside a cannula was inserted through healthy skin at a minimum distance of 2 cm from the ulcer edge, close to the bone, preferentially on dorsal foot side. When the trocar was firmly inserted into the bone, it was pulled out from the cannula. Biopsy needle was then slipped into the cannula and twisted into the bone clockwise. Biopsy needle was then pulled out and the bone was pushed out with the ejector pin into a sterile surgical drape and divided in two parts.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bedside blind bone biopsy procedure
Description: It was performed in the patient's room under aseptic conditions. Pain relievers were given orally within the hour preceding the procedure. Superficial anesthesia was performed firstly subcutaneously and then on the periosteum, Inhaled anesthesia was started concomitantly. Following a short incision with a scalpel, the trocar inside a cannula was inserted through healthy skin at a minimum distance of 2 cm from the ulcer edge, close to the bone, preferentially on dorsal foot side. When the trocar was firmly inserted into the bone, it was pulled out from the cannula. Biopsy needle was then slipped into the cannula and twisted into the bone clockwise. Biopsy needle was then pulled out and the bone was pushed out with the ejector pin into a sterile surgical drape and divided in two parts.
Study: NCT03800082

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: at heart (changed from HEARTPA♀N during usability testing)
Description: An integrated smartphone and web-based intervention (at heart) to provide evidence-informed symptom triage and self-management support to reduce pain and increase health-related quality of life (HRQoL) in women with heart disease. The intervention for participants randomized to the treatment group will consist of regular use of a progressive WebApp that is managed by a Chatbot named 'Holly', in addition to usual care, for a period of 3 months.
Study: NCT05489237

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDRX-42
Description: Administered at assigned doses and schedules once or twice daily in continuous cycles of 28 days each.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDRX-42
Description: Administered at assigned doses and schedules once or twice daily in continuous cycles of 28 days each.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDRX-42
Description: Administered at assigned doses and schedules once or twice daily in continuous cycles of 28 days each.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDRX-42
Description: Administered at assigned doses and schedules once or twice daily in continuous cycles of 28 days each.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDRX-42
Description: Administered at assigned doses and schedules once or twice daily in continuous cycles of 28 days each.
Study: NCT04924101

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion
Study: NCT05671679

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SNAQ app
Description: SNAQ is a smartphone food analysis app that estimates the macronutrient content of a meal, based on a single image. The app first determines meal content in terms of food components with input from the user to correct or add further components (e.g. foods, ingredients, sauces, herbs or seasonings). Then, the total macronutrient and energy content of the meal is determined based on the estimated volume and information from a nutritional database. Of note, the application also allows for assessing nutritional content of packaged foods by means of a barcode scanning function. The user can always adapt proposed nutritional contents at their own discretion. Meal macronutrients alongside the food pictures are collected in a detailed log which allows users to review their dietary choices. The product is not conceived by its manufacturer to be used for medical purposes and can thus not be considered a medical device.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional carbohydrate counting
Description: Patients will follow their traditional methods of carbohydrate counting during the control period. In addition to assess sustainability of the intervention, following the control period, the control group will also go an intervention period of 3 weeks using the SNAQ App.
Study: NCT04763031

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intra-operative Radiation Therapy - IORT
Description: Single dose of 20 Gy
Study: NCT05642949

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHB036C
Description: MHB036C will be administered intravenously at a frequency of once every 3 weeks (Q3W).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHB036C
Description: MHB036C will be administered intravenously at a frequency of once every 3 weeks (Q3W).
Study: NCT06348979

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fiber flowable (SFRC) support below hybrid nanoceramic endocrowns
Description: restoration of endodontically treated teeth by endocrowns

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: all ceramic Endocrowns (emax)
Description: restoration of endodontically treated teeth by endocrowns
Study: NCT05492292

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Perfusion brain scintigraphy imaging
Description: The cerebral perfusion scintigraphy via a SPECT examination aims to analyze the cerebral blood flow and detect possible lesions or inflammations.
Study: NCT05686993

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cinnarizine
Description: Cinnarizine oral 30mg TDS

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NIFEdipine ER
Description: Nifedipine oral 60mg daily extended release
Study: NCT05665387

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.1% STN1013600 ophthalmic solution
Description: 0.1% STN1013600 ophthalmic solution 1 drop BID for 2 months

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.3% STN1013600 ophthalmic solution
Description: 0.3% STN1013600 ophthalmic solution 1 drop BID for 2 months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo ophthalmic solution 1 drop BID for 2 months
Study: NCT04908020

Intervention type: OTHER
Intervention: Follow-up patients
Description: The intervention consists in the assessment of some psychological aspects (post traumatic stress symptoms and coping) of cancer patients in follow-up care, through specific tests. Each patient fills out the test battery during the psychological consult. At the same time, it is involved a parent to collect personal and clinical data through an ad hoc questionnaire.
Study: NCT05624424

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rematazolam Besylate
Description: Anesthesia was induced with Rematazolam Besylate 0.3\~0.5 mg/kg (about 1 minute) by intravenous injection until the loss of consciousness (LoC) and BIS\<60, followed by remimazolam 1-3 mg/kg/h until the end of surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Anesthesia was induced with Propofol 2\~2.5 mg/kg (about 1 minute) by intravenous injection until the loss of consciousness (LoC) and BIS\<60, followed by remimazolam 5\~12 mg/kg/h until the end of surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: Anesthesia was induced with etomidate 0.03 mg/kg (about 1 minute) by intravenous injection until the loss of consciousness (LoC) and BIS\<60, followed by 2 %-3 % Sevoflorane until the end of surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sufentanil
Description: Anesthesia was induced with Sufentanil 0.3\~0.5 ug/kg by intravenous injection after the LoC and BIS\<60.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sufentanil
Description: Anesthesia was induced with Sufentanil 0.3\~0.5 ug/kg by intravenous injection after the LoC and BIS\<60.
Study: NCT06398795

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dual-port Trans-subclavian Thyroid Endoscopic Surgery (DTS).
Description: An innovative surgical approach, Dual-port Trans-subclavian Thyroid Endoscopic Surgery (DTS), presents a unique dual-port endoscopic technique for thyroidectomy. DTS significantly reduces postoperative hospital stay, emphasizing its potential for accelerated patient recovery compared to COT.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional open thyroidectomy (COT)
Description: open thyroidectomy with traditional collar incisions
Study: NCT06104371

Intervention type: DEVICE
Intervention: Magtrace
Description: Sentinel lymph node tracer and metastatic lymph node clip

Intervention type: DEVICE
Intervention: Magtrace
Description: Sentinel lymph node tracer and metastatic lymph node clip
Study: NCT05022264

Intervention type: DIAGNOSTIC_TEST
Intervention: RIA-VS
Description: Measuring vital signs with a new contactless camera technique
Study: NCT05875103

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: linguistic processes
Description: Linguistic processes are assessed by performance score on the following tests:~* naming tests : BNT 34 (Colombo \& Assal, 1992) and semantic naming adapted from the BECS-GRECO (Merck et al., 2011)~* vocabulary test (Mill Hill - Deltour, 1993),~* repetition tests (Gremots - Bézy et al., 2016),~* articulatory speed (Majerus, 2014 ; Roussel et al., 2012)~* semantic matching task adapted from the PPT (Howard \& Patterson, 1992) and from the BECS-GRECO (Merck et al., 2011),~* semantic categorization and attributes adapted from the BECS-GRECO (Merck et al., 2011),~* phonologic and semantic research tasks adapted from the color TMT (D'helia et al., 1996)
Study: NCT05616715

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Peek device
Description: Participants with gummy smile will be recruited from the Dental Clinic of Instituto Universitário Egas Moniz

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Peek device
Description: Participants with gummy smile will be recruited from the Dental Clinic of Instituto Universitário Egas Moniz

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Crown lengthening/gingivectomy
Description: Participante with gummy smile will be recruited from the Dental Clinic of Instituto Universitário Egas Moniz
Study: NCT04924101

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MK-4830
Description: IV infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Boserolimab
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Oral capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: IV infusion
Study: NCT04807829

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nabilone
Description: Nabilone is a synthetic endocannabinoid and CB1 agonist.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inactive placebo comparator