TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06771622

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 1000 mg/m2 PO BID on Days 1-14, Cycled every 21 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 1000 mg/m2 PO BID on Days 1-14, Cycled every 21 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ramucirumab
Description: 8 mg/kg IV on Days 1 and 15, Cycled every 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: 80 mg/m2 IV on Days 1, 8, and 15, Cycled every 28 days
Study: NCT05740956

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10502
Description: HS-10502 will be administered once per day on a continuous dosing schedule starting on Cycle 1 Day 1 (C1D1) in a 28-day treatment cycle.
Study: NCT06771622

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: 5 mg/kg IV on Day 1, Repeat every 2 weeks; or 7.5 mg/kg IV on Day 1, Repeat every 3 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: 400 mg/m2 first infusion, followed by 250 mg/m2 IV weekly; or 500 mg/m2 IV over 2 hours on Day 1 every 2 weeks;

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: 180 mg/m2 IV over 30-90 minutes on Day 1 every 2 weeks
Study: NCT05882786

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Corticosteroid injection
Description: Subacromial injection of 40mg triamcinolone acetonide.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dry Needling
Description: Dry needling treatment to the supraspinatus, infraspinatus, and subscapularis muscles tendons.
Study: NCT05783700

Intervention type: DIAGNOSTIC_TEST
Intervention: BIOIMPEDANCEMETRY
Description: The impedance of cellular tissue can be modeled as a resistor (representing the extracellular path) in parallel with a resistor and capacitor in series (representing the intracellular path, the resistance that of intracellular fluid and the capacitor the cell membrane). This results in a change in impedance versus the frequency used in the measurement. Whole body impedance measurement is generally measured from the wrist to the ipsilateral ankle and uses either two (rarely) or four (overwhelmingly) electrodes. In the 2-elctrode (bipolar) configuration a small current on the order of 1-10 μA is passed between two electrodes, and the voltage is measured between the same whereas in the tetrapolar arrangement resistance is measured between as separate pair of proximally located electrodes. The tetrapolar arrangement is preferred since measurement is not confounded by the impedance of the skin-electrode interface
Study: NCT06771622

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin
Description: 400 mg/m2 IV on Day 1 every 2 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-FU
Description: 400 mg/ m2 IV bolus on Day 1, followed by 1200 mg/m2/day x 2 days (total 2400 mg/m2 over 46-48 hours) IV continuous infusion Repeat every 2 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: 240 mg/kg IV on Day 1 Cycled every 21 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin-bound paclitaxel
Description: 125 mg/m2 IV on day 1 and Day 8 Cycled every 21 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200 mg IV day 1; given every 21 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: 1000 mg/m2 IV days 1 and 8
Study: NCT06774157

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A session combining motor imagery and listening to low frequency sounds
Description: Prospective study of the efficacy of the Allyane procedure after knee sprain

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical therapy including exercises
Description: Active extension (e.g. by lateral raising of the quadriceps, strengthening of the quadriceps) quadriceps);~* Flexor inhibition (e.g. massage, hamstring stretching);~* Active flexion (e.g. strengthening the flexors)
Study: NCT06770543

Intervention type: OTHER
Intervention: Inclisiran
Description: There is no treatment allocation. Patients administered Leqvio by prescription that have started before inclusion of the patient into the study will be enrolled.
Study: NCT06772402

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: GCB-001
Description: GCB-001 is a self-complementary AAV9 carrying a full length human SMN transgenetic product.
Study: NCT05613413

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cabozantinib 40 MG
Description: Cabozantinib is taken my mouth

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab 200mg
Description: Pembrolizumab is given intravenously
Study: NCT05613413

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab 400mg
Description: Pembrolizumab is given intravenously
Study: NCT06775171

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: video training group
Description: Creation of the Education Booklet While creating the education booklet that includes the definition of BY, the areas where it frequently develops, risk factors, classification, prevention and situations where it requires professional support, it will be created by the researcher by scanning the current literature and taking the opinions of the Faculty Members from the Nursing Fundamentals field in terms of scope, comprehensibility and scientific content.~Creation of Videos The videos will be prepared in five separate videos that will include the definition of BY, the areas where it frequently develops, risk factors, classification, prevention and situations where it requires professional support in line with the education booklet. QR codes of the prepared videos will be created. Each video will be planned to be 5-10 minutes. The videos will be checked by the Advisor Faculty Member and corrections will be made in line with his/her suggestions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: video training group
Description: Creation of the Education Booklet While creating the education booklet that includes the definition of BY, the areas where it frequently develops, risk factors, classification, prevention and situations where it requires professional support, it will be created by the researcher by scanning the current literature and taking the opinions of the Faculty Members from the Nursing Fundamentals field in terms of scope, comprehensibility and scientific content.~Creation of Videos The videos will be prepared in five separate videos that will include the definition of BY, the areas where it frequently develops, risk factors, classification, prevention and situations where it requires professional support in line with the education booklet. QR codes of the prepared videos will be created. Each video will be planned to be 5-10 minutes. The videos will be checked by the Advisor Faculty Member and corrections will be made in line with his/her suggestions.
Study: NCT03981432

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-Fixed
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive a fixed meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-Fixed
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive a fixed meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-Fixed
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive a fixed meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-AdLib
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-AdLib
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-AdLib
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EX-AdLib
Description: condition with an acute exercise set 30 minutes before the lunch meal that will be served ad libitum This will be a 30-minute exercise set at 65% of their capacities (cycling), 30 minutes before lunch.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EX-AdLib
Description: condition with an acute exercise set 30 minutes before the lunch meal that will be served ad libitum This will be a 30-minute exercise set at 65% of their capacities (cycling), 30 minutes before lunch.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EX-AdLib
Description: condition with an acute exercise set 30 minutes before the lunch meal that will be served ad libitum This will be a 30-minute exercise set at 65% of their capacities (cycling), 30 minutes before lunch.
Study: NCT05452967

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Distraction technique
Description: The post operative pediatric patients will be given mobile phone in recovery for plying games and watching cartoons and with the help of this distraction technique will assess that routine rescue analgesia is needed or not
Study: NCT04869267

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Commitment Therapy (ACT)
Description: Session 1:~This session aims to let the participants get familiar with the interventionist. The interventionist will tell them the purpose of the program and basic rules. And the interventionist will promise their privacy protection.~Session 2:~This session includes how to separate thoughts/feelings/sensations related to diagnose with advanced lung cancer and experience of fatigue with facts and see these feelings in an objective way with observing self.~Session 3:~This session mainly aims to help participants understand the importance of values, differentiate values from goals and clarify their personal values.~Session 4:~This session aims at helping patients practice to engaging in committed action based on chosen values, motivated to change behavior in consistency with life direction and health goal.

Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: The usual care mainly includes treatments and daily care during admission, medication instructions, diet and exercise advice, retest recommendations when discharge
Study: NCT06349057

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: reducing anticholinergic burden
Description: In the intraoperative and postoperative periods instead of drugs with high anticholinergic burden; drugs with low burden will be preferred.
Study: NCT04388501

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.
Study: NCT05202145

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2050
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2050
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2050
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine
Description: Oral capsule.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Oral capsule.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MMF
Description: Oral tablet.
Study: NCT04805086

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MON002
Description: Autologous monocytes
Study: NCT05199324

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral fluoroquinolones (most commonly, ciprofloxacin) or oral trimethoprim-sulfamethoxazole
Description: Clinically stable / non-critically ill inpatients with uncomplicated Gram-negative bacteraemia randomised to the intervention arm will be switched early to oral antibiotics (within 72 hours from index blood culture collection)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care intravenous antibiotics (e.g. ceftriaxone, cefazolin)
Description: Clinically stable / non-critically ill inpatients with uncomplicated Gram-negative bacteraemia randomised to the standard arm will continue to receive an active intravenous antibiotic therapy for at least another 24 hours post-randomisation before clinical re-assessment and decision making by the treating doctor
Study: NCT06020235

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5% Nu-3 gel
Description: The gel is called Nu-3 which is either applied once per day or twice per day to the infected ulcer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5% Nu-3 gel
Description: The gel is called Nu-3 which is either applied once per day or twice per day to the infected ulcer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10% Nu-3 gel
Description: The gel is called Nu-3 which is either applied once per day or twice per day to the infected ulcer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10% Nu-3 gel
Description: The gel is called Nu-3 which is either applied once per day or twice per day to the infected ulcer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo gel is either applied once per day or twice per day to the infected ulcer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo gel is either applied once per day or twice per day to the infected ulcer.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo gel is either applied once per day or twice per day to the infected ulcer.
Study: NCT06361641

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Monocytes signatures in myeloproliferative neoplasms at diagnosis
Description: The monocytes signatures will be perform from a peripheral blood sample. The signature will be derived from (i) surface marker expression, (ii) cytokines profiles, (iii) genes expression.
Study: NCT05772897

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Circle of Security Parenting program
Description: The Circle of Security Parenting (COSP) program is an 8- week group parenting course that was designed using decades of attachment research to foster a secure attachment by teaching parents to read and respond to infant cues, and to recognize the interplay between their own psychological and emotional experiences and the emotional regulation of their infants. The COSP program provides parents with relationship tools and techniques for understanding their children's needs in new ways that provide lasting security for the child and more satisfaction for the parent. There are two major themes in the program: 1) teaching parents how to read their children's behavior and use it as a guide for meeting their needs and 2) helping parents to understand how their own early attachment relationships have influenced them as a person, and how those influences show up in their parenting and impact their ability to help regulate their child and respond to their needs.
Study: NCT06488261

Intervention type: BIOLOGICAL
Intervention: AVR-RD-02
Description: No study drug is administered in this study. Subjects who received AVR-RD-02 in a separate parent trial will be evaluated in this trial for long-term safety.
Study: NCT04728490

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Allogenic transplantation transplantation
Description: Haplo-identical transplantation with the use of Treosulfan, Thiotepa and Fludarabine in conditioning regimen.
Study: NCT05434039

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: diclofenac phonophoresis
Description: the patients will be in comfortable position and apply diclofenac phonophoresis on upper trapezius and suboccipital muscle by ultrasound device. diclofenac gel was applied circularly with a thickness of 2-3 mm. Then ultrasound with was applied with 1 MHz frequency and 1.5 Wt/cm2 power over the trigger points on the trapezius and suboccipital muscle, for 10 min.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high power pain threshold ultrasound
Description: the patients will be in comfortable position and The frequency was set to 1 MHz, and the intensity will be increased from 0.5 to 2 until the patient reported an unpleasant sensation. The probe was held there for 4 s; then, the intensity was reduced by 50%, and the probe will be moved over and around the trigger point. This process is done several times for three minutes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: the patient will receive an active range of motion exercise, stretching and strengthening of all cervical muscles

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional therapy
Description: the patient will receive an active range of motion exercise, stretching and strengthening of all cervical muscles

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional therapy
Description: the patient will receive an active range of motion exercise, stretching and strengthening of all cervical muscles
Study: NCT06770205

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional physical therapy
Description: hot pack and TENS for 10 minutes and massage that will as 3 sessions per week for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kendall Exercise Group A
Description: The group B will receive Proprioceptive Neuromuscular Facilitation technique for stretching and rhythmic stabilization technique for strengthening. Proprioceptive Neuromuscular Facilitation (PNF) is a stretching technique utilized to improve muscle elasticity and has been shown to have a positive effect on active and passive range of motions. The PNF group performed the intervention for 30 minutes a day, six times a week, a total of 24 times. (13) In this group, two types of PNF techniques were given:~1. first is strengthening technique included rhythmic stabilization that is characterized by alternating isometric contractions against resistance, no motion intended to apply for the weak muscles of upper cross syndrome included deep neck flexors specifically lower trapezius and serratus anterior.~2. Second is stretching technique included contract relax that is resisted isotonic contractions of the restricting muscles (antagonists) followed by relaxation and movement
Study: NCT04506983

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GPC3-CAR-T cells
Description: Patients with hepatocellular carcinoma will be enrolled, and GPC3-CAR-T cells will be intravenously infused with a escalated dose of 1×106 /3×106/10×106GPC3-CAR-T cells.
Study: NCT06549179

Intervention type: DIAGNOSTIC_TEST
Intervention: AMSE
Description: Evaluation of the performance of the French-language AMSE tool used by non-expert psychiatrists and psychologists, trained in the tool, in the identification of ASD in adults.
Study: NCT06773676

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: B-Cure laser pro
Description: The B-Cure laser pro is a portal, non-invasive, photobiomodulation device, that emits light in the near infrared (808nm) over an area of 1X4.5 cm2 with power output of 250mW, and energy dose of 1J/cm2.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: The sham device is externally identical to active, emits the same guiding light and sound but does not emit the therapeutic near infrared invisible rays
Study: NCT05601557

Intervention type: OTHER
Intervention: There is no intervention
Description: The genotype of the patients was analyzed.

Intervention type: OTHER
Intervention: There is no intervention
Description: The genotype of the patients was analyzed.

Intervention type: OTHER
Intervention: There is no intervention
Description: The genotype of the patients was analyzed.

Intervention type: OTHER
Intervention: There is no intervention
Description: The genotype of the patients was analyzed.

Intervention type: OTHER
Intervention: There is no intervention
Description: The genotype of the patients was analyzed.