TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06283485

Intervention type: DEVICE
Intervention: ultrasound examination
Description: Phase 1 1: Taking ultrasound images from healthy volunteers (150 volunteers) to produce artificial intelligence - How to take PENG and Suprainguinal Fascia Iliaca Block sonoanatomical images is as follows.~Phase 2: In the second phase of the study, Smart Alfa Teknoloji San. and Tic. Inc. Artificial intelligence technology called Nerveblox, which was developed with the data received in the first stage with the support of the company, will be used. It is the validation and accuracy study of the artificial intelligence technology developed in the first stage. The accuracy study will be conducted on 40 healthy volunteers. 20 men and 20 women will be included in the study.

Intervention type: DEVICE
Intervention: ultrasound examination
Description: Phase 1 1: Taking ultrasound images from healthy volunteers (150 volunteers) to produce artificial intelligence - How to take PENG and Suprainguinal Fascia Iliaca Block sonoanatomical images is as follows.~Phase 2: In the second phase of the study, Smart Alfa Teknoloji San. and Tic. Inc. Artificial intelligence technology called Nerveblox, which was developed with the data received in the first stage with the support of the company, will be used. It is the validation and accuracy study of the artificial intelligence technology developed in the first stage. The accuracy study will be conducted on 40 healthy volunteers. 20 men and 20 women will be included in the study.
Study: NCT06007378

Intervention type: OTHER
Group type: OTHER
Intervention: Bupivacaine and ketamine
Description: Bilateral erector spinae plane block (bupivacaine and ketamine)

Intervention type: OTHER
Group type: OTHER
Intervention: Bupivacaine and transdermal fentanyl patch
Description: Bilateral erector spinae plane block (bupivacaine) and transdermal fentanyl patch

Intervention type: OTHER
Group type: OTHER
Intervention: Bupivacain
Description: Bilateral erector spinae plane block (bupivacaine)
Study: NCT05217901

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 14C-labeled ASP0367
Description: Oral
Study: NCT06646991

Intervention type: DEVICE
Group type: OTHER
Intervention: Nasal canula - up to 6 liters per minute
Description: Oxygen will be administered via nasal cannula up to 6 liters per minute during this period.~Oxygen flow rates will be adjusted manually, with a gradual increase in flow rates to achieve a oxygen flow rates for reach the peripheral oxygen saturation (SpO2) target (92% for non chronic obstructive pulmonary disease (non COPD) patient and 90% for chronic obstructive pulmonary disease (COPD) patient).~The steady state will be defined by a fixed oxygen flow rate and a stable SpO2 around the target ±2% for 15 minutes. The average oxygen flow rate during the last five minutes will be used.

Intervention type: DEVICE
Group type: OTHER
Intervention: Nasal canula - up to 6 liters per minute
Description: Oxygen will be administered via nasal cannula up to 6 liters per minute during this period.~Oxygen flow rates will be adjusted manually, with a gradual increase in flow rates to achieve a oxygen flow rates for reach the peripheral oxygen saturation (SpO2) target (92% for non chronic obstructive pulmonary disease (non COPD) patient and 90% for chronic obstructive pulmonary disease (COPD) patient).~The steady state will be defined by a fixed oxygen flow rate and a stable SpO2 around the target ±2% for 15 minutes. The average oxygen flow rate during the last five minutes will be used.

Intervention type: DEVICE
Group type: OTHER
Intervention: Nasal canula - up to 15 liters per minute
Description: Oxygen will be administered via nasal cannula up to 15 liters per minute during this period.~Oxygen flow rates will be adjusted manually, with a gradual increase in flow rates to achieve a oxygen flow rates for reach the SpO2 target (92% for non COPD patient and 90% for COPD patient).~The steady state will be defined by a fixed oxygen flow rate and a stable SpO2 around the target ±2% for 15 minutes. The average oxygen flow rate during the last five minutes will be used.

Intervention type: DEVICE
Group type: OTHER
Intervention: Open oxygen mask
Description: Oxygen will be administered via an open during this period. Oxygen flow rates will be adjusted manually, with a gradual increase in flow rates to achieve a oxygen flow rates for reach the SpO2 target (92% for non COPD patient and 90% for COPD patient).~The steady state will be defined by a fixed oxygen flow rate and a stable SpO2 around the target ±2% for 15 minutes. The average oxygen flow rate during the last five minutes will be used.

Intervention type: DEVICE
Group type: OTHER
Intervention: Simple oxygen face mask
Description: Oxygen will be administered via simple oxygen face mask during this period. Oxygen flow rates will be adjusted manually, with a gradual increase in flow rates to achieve a oxygen flow rates for reach the SpO2 target (92% for non COPD patient and 90% for COPD patient).~The steady state will be defined by a fixed oxygen flow rate and a stable SpO2 around the target ±2% for 15 minutes. The average oxygen flow rate during the last five minutes will be used.
Study: NCT05218083

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REmotely monitored, Mobile health supported Multidomain Rehabilitation Program with High Intensity Interval Training (REMM-HIIT)
Description: REmotely Monitored, Mobile health-supported, High Intensity Interval Training consists of remotely monitored tailored, structured, progressive multidomain physical rehabilitation \& personalized instruction \& coaching.~Patients complete 3 structured exercise sessions/week consisting of HIIT, strength, balance, and mobility exercises. Following warmup, patients increase workload at a heart rate corresponding to 95% VO2peak for 1-minute before returning to warm-up speed for 1-minute at a heart rate corresponding to 60% VO2peak.~Strength includes functional strengthening exercises for lower extremities \& general resistance exercises for major muscle groups.~Balance incorporates static \& dynamic exercises, including progressively narrowing base of support with eyes open or closed, reaching forward \& backward starting within base of support \& progressing to outside base of support.~Mobility rehabilitation includes dynamic start/stop while walking and changing direction while walking.
Study: NCT05899218

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Critical Narrative Development
Description: Participants are asked to answer two prompts (describe an experience where you have felt seen as an LGBTQ+ person of color and describe an experience where you have felt unseen as an LGBTQ+ person of color).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Critical Narrative Development
Description: Participants are asked to answer two prompts (describe an experience where you have felt seen as an LGBTQ+ person of color and describe an experience where you have felt unseen as an LGBTQ+ person of color).
Study: NCT06105697

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood flow restriction Running on Treadmill
Description: Soccer players included in experimental group I will carry out this program for 6 weeks, setting the blood pressure to \~ 60% of limb occlusion pressure (AOP). They will run for 4 sets of 5 minutes, separated by 1 minute of rest, at 50-60% of their maximum Aerobic Speed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Running on Treadmill
Description: Soccer players included in experimental group II will carry out the program for 6 weeks without occlude the blood pressure. They will run for 4 sets of 5 minutes, separated by 1 minute of rest, at 50-60% of their maximum Aerobic Speed.
Study: NCT06544265

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SynKIR-310
Description: Autologous T Cells transduced with CD19 KIR-CAR
Study: NCT06260683

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine Replacement
Description: Given nicotine patches and nicotine lozenges

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vaping
Description: Given Preferred Flavor e-liquid

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vaping
Description: Given Tobacco flavored e-liquid
Study: NCT06319963

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Two IM injections Lenti-HPV-07
Description: two Lenti-HPV-07 intramuscular injections one month apart
Study: NCT06636773

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diet
Description: A reduced energy diet ranging from 1200-2100 kilocalories per day will be recommended for participants.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise
Description: Physical activity will be recommended in the form of aerobic types of activity such as brisk walking and will progress from an initial amount of 100 minutes per week to 300 minutes per week across the initial 6 months of the intervention, with this level of physical activity continuing to be recommended between months 7-12.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Sessions
Description: Participants will be provided weekly group-based behavioral session for months 1-6, with these sessions being offered twice per month during months 7-12 to assist in supporting recommended changes in energy intake (diet) and physical activity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Sessions
Description: Participants will be provided weekly group-based behavioral session for months 1-6, with these sessions being offered twice per month during months 7-12 to assist in supporting recommended changes in energy intake (diet) and physical activity.
Study: NCT06319963

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: One IM injection Lenti-HPV-07
Description: a single intramuscular injection prior to receiving a standard of care 28 days at least after the injection.
Study: NCT05527288

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: [18F]florbetaben
Description: All eligible patients will receive a single administration of the imaging agent \[18F\]florbetaben at a radioactive dose of 300 MBq.
Study: NCT05179655

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Regulation Individual Therapy for Adolescents (ERITA)
Description: The ERITA intervention as add-on to TAU consists of 11 weeks, manualized online therapy based on the methods of Cognitive Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and Acceptance and Commitment Therapy (ACT) adapted for youth. The ERITA content consists of psychoeducation, emotion recognition, awareness training and theory of emotion regulation, including acceptance and validation skills.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as usual
Description: Within Mental Health Services in Denmark child and adolescent psychiatrists provide specialized treatment for young psychiatric patients as outpatient services. In this trial the control intervention is treatment as usual (TAU) and consists of clinical assessment and treatment for patient's current primary psychiatric condition. TAU encounters a variety of clinical treatment and assessment offers, however, all within the field of expertise in child and adolescent psychiatry; out-patient care may consist of treatment for OCD, eating disorders, psychoses or affective disorders. TAU may consist of pharmacological treatment, Family-Based Treatment (FBT), Cognitive Behavioral Therapy (CBT), supportive counselling and/or psychoeducation.

Intervention type: OTHER
Group type: OTHER
Intervention: Treatment as usual
Description: Within Mental Health Services in Denmark child and adolescent psychiatrists provide specialized treatment for young psychiatric patients as outpatient services. In this trial the control intervention is treatment as usual (TAU) and consists of clinical assessment and treatment for patient's current primary psychiatric condition. TAU encounters a variety of clinical treatment and assessment offers, however, all within the field of expertise in child and adolescent psychiatry; out-patient care may consist of treatment for OCD, eating disorders, psychoses or affective disorders. TAU may consist of pharmacological treatment, Family-Based Treatment (FBT), Cognitive Behavioral Therapy (CBT), supportive counselling and/or psychoeducation.
Study: NCT06636773

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic + Yoga Exercise
Description: Physical activity will be recommended in the form of a combination of aerobic types of activity, such as brisk walking, and yoga. Aerobic activity will progress from 60 minutes per week to 180 minutes per week across the initial 6 months of the intervention. Yoga will progress from 40 minutes per week to 120 minutes per week across the initial 6 months of the intervention. When combined this will progress from a total of 100 minutes per week to 300 minutes per week across the initial 6 months of treatment. This level of physical activity will continue to be recommended between months 7-12.
Study: NCT06641271

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Closed Loop Trans-Auricular Vagus Nerve Stimulation System
Description: A closed loop system that delivers stimulation to the vagus nerve via the ear non-invasively following a trigger event.
Study: NCT05168657

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bionic Pancreas
Description: 14 days using the insulin-only configuration of the iLet Bionic Pancreas (Beta Bionics, Inc.), which automates insulin delivery, as the only intended mode of insulin delivery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bionic Pancreas
Description: 14 days using the insulin-only configuration of the iLet Bionic Pancreas (Beta Bionics, Inc.), which automates insulin delivery, as the only intended mode of insulin delivery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bionic Pancreas
Description: 14 days using the insulin-only configuration of the iLet Bionic Pancreas (Beta Bionics, Inc.), which automates insulin delivery, as the only intended mode of insulin delivery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bionic Pancreas
Description: 14 days using the insulin-only configuration of the iLet Bionic Pancreas (Beta Bionics, Inc.), which automates insulin delivery, as the only intended mode of insulin delivery.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: 14 days of the participant's usual care of their type 1 diabetes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: 14 days of the participant's usual care of their type 1 diabetes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: 14 days of the participant's usual care of their type 1 diabetes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: 14 days of the participant's usual care of their type 1 diabetes
Study: NCT05804240

Intervention type: DIAGNOSTIC_TEST
Intervention: 3D TEE RVEF
Description: With TEE package software, the investigators measure and calculate 3D TEE RVEF using mid esophageal 4 chamber view

Intervention type: DIAGNOSTIC_TEST
Intervention: 3D TEE RVEF
Description: With TEE package software, the investigators measure and calculate 3D TEE RVEF using mid esophageal 4 chamber view

Intervention type: DIAGNOSTIC_TEST
Intervention: 3D TEE RVEF
Description: With TEE package software, the investigators measure and calculate 3D TEE RVEF using mid esophageal 4 chamber view
Study: NCT05372211

Intervention type: OTHER
Intervention: not use of any intervention
Description: not use of any intervention

Intervention type: OTHER
Intervention: not use of any intervention
Description: not use of any intervention

Intervention type: OTHER
Intervention: not use of any intervention
Description: not use of any intervention
Study: NCT04651582

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Training
Description: 20 hours of computerized activities designed to improve processing speed and divided attention

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Stimulating Activities
Description: 20 hours of traditional computer games
Study: NCT05923320

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: training
Description: The experimental group was given training on infancy vaccines and breastfeeding. The times of the trainings are determined based on the Postpartum Care Management Guide of the Ministry of Health. In the hospital on the first day after birth, 2-7. days and 30-42. Three days in total, trainings were given on breastfeeding and childhood vaccinations by making home visits. The training content has been prepared by taking into account the Ministry of Health Breastfeeding Guide (5) and the Ministry of Health's vaccination calendar and the Primary Care Vaccine Guide. The trainings will be given to the puerperant women individually. About 30 minutes of training will be given and their questions, if any, will be answered.
Study: NCT06080191

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD19-CAR_Lenti_ALLO
Description: Biological/Vaccine: CD19-CAR_Lenti_ALLO~A single infusion of CD19-CAR_Lenti_ALLO on Day 0
Study: NCT06566950

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low load-BFRt
Description: The participants' two legs will be subjected to 70% arterial occlusion pressure when the physical therapist applies the BFR cuffs. After that, participants will be required to complete eccentric exercises with a maximum repetition count of 30%, such as stairs, single leg squat, and single leg deadlift.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham Low load-BFRt
Description: The participants' two legs will be subjected to 10% arterial occlusion pressure when the physical therapist applies the BFR cuffs. After that, participants will be required to complete eccentric exercises with a maximum repetition count of 30%, such as stairs, single leg squat, and single leg deadlift.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High load-Eccentric training
Description: The physical therapist will instruct the participants to complete eccentric exercises at a maximum of 70% repetitions, such as stairs, single leg squat, and single leg deadlift.
Study: NCT06565741

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: MoLEP
Description: Patients with an indication for surgery for BPH via EEAP with a prostate volume exceeding 80cc will be included in the study on a prospective basis. Surgery will be randomly assigned using MoLEP or ThuFLEP. A qualified surgeon, having completed their learning curve for endoscopic enucleation (more than 50 cases) and possessing experience with both laser types, will perform the surgical procedure.
Study: NCT05988216

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BRL-301
Description: Single dose of Allogeneic Anti-CD19 CAR T cells will be infused
Study: NCT06222476

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dorzagliatin
Description: Dorzagliatin will be initiated and maintained at 75mg twice a day
Study: NCT06565741

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ThuFLEP
Description: Patients with an indication for surgery for BPH via EEAP with a prostate volume exceeding 80cc will be included in the study on a prospective basis. Surgery will be randomly assigned using MoLEP or ThuFLEP. A qualified surgeon, having completed their learning curve for endoscopic enucleation (more than 50 cases) and possessing experience with both laser types, will perform the surgical procedure.
Study: NCT05984329

Intervention type: OTHER
Intervention: Retrospective analysis of patients' choice
Description: Retrospective analysis of patients' choice of tonic or Burst DR(TM) waves for their analgesic effect.

Intervention type: OTHER
Intervention: Retrospective analysis of patients' choice
Description: Retrospective analysis of patients' choice of tonic or Burst DR(TM) waves for their analgesic effect.
Study: NCT05714150

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Complex Balance Tasks
Description: The intervention will consist of a single session of practicing complex (cognitively engaging) balance tasks using an exergaming balance platform.
Study: NCT06345183

Intervention type: COMBINATION_PRODUCT
Intervention: Nivolumab + Ipilimumab combination therapy
Description: As per product label

Intervention type: COMBINATION_PRODUCT
Intervention: Pembrolizumab + Lenvatinib combination therapy
Description: As per product label
Study: NCT05556031

Intervention type: OTHER
Intervention: Standard care
Description: Standard clinical care
Study: NCT06222476

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gliclazide
Description: Gliclazide will be initiated and maintained at 30mg once a day
Study: NCT05528094

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: GeniusDrops
Description: The active ingredients listed below are safe and the study sponsor has noted there are no known side effects of the supplement. The main ingredients are:~Hibiscus flower- Has been shown to boost oxygenation to the brain and vital organs. Has also demonstrated efficacy for boosting the immune system.~Gingko leaf- Has been shown to stimulate memory by increasing mental sharpness and clarity.~Rhodiola- Helps regulate energy and stress level. Gotu kola- Has been shown to have impacts on reducing anxiety. Licorice Root- Helps boost the key brain neurotransmitter called Brain Derived Neurotrophic factor which can help with cognitive development Peppermint Leaf- Reduces fatigue while helping improve cognitive abilities. Has also been shown to promote immune system function.
Study: NCT06321042

Intervention type: DEVICE
Intervention: Knee arthroplasty
Description: Knee arthroplasty surgery with perseus orthokey alignment device
Study: NCT06641271

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Placebo
Description: A closed-loop vagus nerve stimulation device that can deliver sham stimulation to the ear to simulate stimulation of the vagus nerve.
Study: NCT04619472

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulmonary Radiofrequency Ablation System and the Disposable Pulmonary Radiofrequency Ablation Catheter
Description: The conjunction of the pulmonary RFA system with the disposable pulmonary RFA catheter developed by Hangzhou Broncus Medical Co., Ltd. is aim to specifically target lung tumors. The ablation catheter is designed to reach the tumor through the bronchial pathway.
Study: NCT06549270

Intervention type: DRUG
Intervention: MAbs
Description: Monthly or quarterly mAbs administration

Intervention type: DRUG
Intervention: MAbs
Description: Monthly or quarterly mAbs administration
Study: NCT06585579

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mucogyne Ovule
Description: In Mucogyne group, patient will receive 2 boxes of Mucogyne® ovule. 24 hours after intervention, the patient will apply Mucogyne® ovule, 1 ovule per day for 10 days, to be repeated as needed (for practices' homogenisation, after the 10th day, it is recommended to apply one ovule every second day, until EOS visit)