TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05558657

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based, acupressure combined with nursing education
Description: The intervention group will focus on 11 acupoints on the abdomen (RN12, RN4, ST25), back (BL20, BL21, BL22, BL23, BL24, BL25), and limbs (LI4, ST36). The participants or their caregivers can perform acupressure 30 minutes after meals and twice a day. Participants can choose between two sets of acupressure: (1) Acupressure of the abdominal and back acupoints in a seated position, or (2) Acupressure of the abdominal and limb acupoints in a supine position. Each session lasts approximately 15 minutes.~Besides, the intervention group will also receive nursing education on the basis of receiving acupressure intervention including (1) dietary guidance: help patients to formulate a reasonable diet plan, (2) cultivate regular defecation habits, (3) understand appropriate defecation environments and postures, and (4) Moderate exercise to increase gastrointestinal motility.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home-based, manual light touch of the abdomen combined with nursing education
Description: Control group or their caregivers will apply the manual light touch to the abdomen in any direction or body position at home. In keeping consistent with the intervention group, abdomen touching will also be administered twice daily for approximately 15 minutes each for 10 days. Participants will also receive nursing education.
Study: NCT05716698

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pleurotus citrinopileatus after bio-optics (10 ug group)
Description: The participants took D2 10ug per day for a total of 4 weeks.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pleurotus citrinopileatus after bio-optics (100 ug group)
Description: The participants took D2 100ug per day for a total of 4 weeks.
Study: NCT06610617

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation (tDCS)
Description: tDCS designed to facilitate the excitability of the left dlPFC or sham stimulation on separate visits separated by at least one week in random order, using a double-blinded, within-subject crossover design. Electrode placement and current parameters will be optimized to each participant with the goal of generating an average electric field of 0.25 V/m within the left dlPFC. The direct current delivered by any one electrode will not exceed 2.0 mA; the total amount of current from all electrodes will not exceed 4 mA using the Stimweaver algorithm. Each 20-minute session will begin and end with a 60-second ramp up/down of current amplitude to maximize comfort

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation (tDCS)
Description: tDCS designed to facilitate the excitability of the left dlPFC or sham stimulation on separate visits separated by at least one week in random order, using a double-blinded, within-subject crossover design. Electrode placement and current parameters will be optimized to each participant with the goal of generating an average electric field of 0.25 V/m within the left dlPFC. The direct current delivered by any one electrode will not exceed 2.0 mA; the total amount of current from all electrodes will not exceed 4 mA using the Stimweaver algorithm. Each 20-minute session will begin and end with a 60-second ramp up/down of current amplitude to maximize comfort

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham tDCS
Description: Active sham in which very low-level currents (0.5 mA total) will be transferred between electrodes in close proximity on the scalp throughout the entire 20-minute session. This intervention delivers currents and mimics the sensations induced by tDCS, but does not significantly influence cortical tissue.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham tDCS
Description: Active sham in which very low-level currents (0.5 mA total) will be transferred between electrodes in close proximity on the scalp throughout the entire 20-minute session. This intervention delivers currents and mimics the sensations induced by tDCS, but does not significantly influence cortical tissue.
Study: NCT06669026

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: vitamin D loaded Poly lactic-co-glycolic acid nanoparticles gel
Description: Scaling and root debridement then inject gel in the pocket

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: vitamin D3 gel (regular non-nanoparticle form)
Description: Scaling and root debridement then inject gel in the pocket

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Poly lactic-co-glycolic acid nanoparticles placebo gel
Description: Scaling and root debridement then inject gel in the pocket

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: only mechanical debridement
Description: Scaling and root debridement

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: only mechanical debridement
Description: Scaling and root debridement

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: only mechanical debridement
Description: Scaling and root debridement

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: only mechanical debridement
Description: Scaling and root debridement
Study: NCT06670157

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Detachable Clip
Description: After the varicose vessels basically disappeared under the endoscope, the removable titanium clamp was removed
Study: NCT06669195

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intravascular lithotripsy group
Description: 20 subjects with stent under-expansion in calcified coronary lesions who met the inclusion/exclusion criteria were enrolled; subjects were assigned to the treatment group of Intravascular lithotripsy group.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: high-pressure balloon group
Description: 20 subjects with stent under-expansion in calcified coronary lesions who met the inclusion/exclusion criteria were enrolled; subjects were assigned to the treatment group of high-pressure balloon group.
Study: NCT06669468

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PFME
Description: All patients were asked to mark the exercise at a daily home schedule. Patients who did not complete more than 20% of the list according to the daily home program were excluded from the study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PFME + Anal ES
Description: Anal ES was applied 3 days a week, 20 minutes a day, for a total of 24 sessions for 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PFME + Perineal ES
Description: Perineal ES was applied 3 days a week, 20 minutes a day, for a total of 24 sessions for 8 weeks.
Study: NCT05239039

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: spesolimab
Description: spesolimab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: spesolimab
Description: spesolimab
Study: NCT06474260

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: One All Intervention
Description: One-all is a Three-year curriculum targeted at specific outcomes for each yearfacilitated by young people from the community. The facilitators are inducted througha rigorous facilitators programme of three to five months' length. The facilitators areencouraged to adapt the program to their needs and provide the programme incustomized forms appropriate and as required for the communities. The interventionhas thus far been provided to the fishermen communities in Chennai and anecdotalfield evidence suggest, gains in the intended goals. After these experiences theintervention was being tried amongst the tribal adolescents in Gudalur. One-alltargets to provide the undermentioned skills to achieve the mentioned Goals andSkills:~* self-management • understanding feelings~* social awareness • conflict resolution~* relationship skills • empathy building~* self-awareness Skills •nurturing interpersonal relationships~* identity building • awareness about gender stereotypes
Study: NCT06671626

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subcortical Stimulation
Description: Subcortical simulation of the deep brain stimulation surgery target site will be applied by clinically placed deep brain stimulation electrodes at the previously determined therapeutic setting
Study: NCT06670248

Intervention type: PROCEDURE
Intervention: Debridement Surgery
Description: Surgical debridement of burn wounds involving ≥ 20% of the TBSA, including debrided and donor sites.

Intervention type: DIAGNOSTIC_TEST
Intervention: Sdc-1 Level Measurement
Description: Measurement of plasma sdc-1 levels in different situations to assess endothelial glycocalyx damage using an enzyme-linked immunosorbent assay (ELISA):~Preoperatively:~* Upon admission to the Burn Unit.~* 24 hours after admission to the Burn Unit.~* Prior to the start of surgery, after anesthetic induction.~* If surgery is performed after the fifth day following the burn, an additional sdc-1 measurement will be taken on the fifth day of hospital admission.~Postoperatively:~* 6 hours after surgery.~* 24 hours after surgery.~* 48 hours after surgery.
Study: NCT06674980

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care - DFU
Description: Beginning at the screening visit, participants will receive weekly treatment with standard of care (cleaning, debridement, ulcer moisture balance, and offloading) until ulcer closure, or a maximum of 12 weeks, whichever occurs first.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AM/Single - DFU
Description: Participants will receive weekly applications of AM/Single and Standard of Care until ulcer closure, or a maximum of 12 weeks, whichever occurs first.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AM/Double - DFU
Description: Participants will receive weekly applications of AM/Double and Standard of Care until ulcer closure, or a maximum of 12 weeks, whichever occurs first.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care - VLU
Description: Beginning at the screening visit, participants will receive weekly treatment with standard of care (cleaning, debridement, ulcer moisture balance, and compression) until ulcer closure, or a maximum of 12 weeks, whichever occurs first.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AM/Single - VLU
Description: Participants will receive weekly applications of AM/Single and Standard of Care until ulcer closure, or a maximum of 12 weeks, whichever occurs first.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AM/Double - VLU
Description: Participants will receive weekly applications of AM/Double and Standard of Care until ulcer closure, or a maximum of 12 weeks, whichever occurs first.
Study: NCT06103136

Intervention type: DEVICE
Intervention: Laparoscopic surgery using the Maestro Platform
Description: Patients scheduled for laparoscopic surgery will be operated on as per standard of care, using standard port, surgical table and instrument placements (following local applicable guidelines), and off-the-shelf surgical equipment. Standard of care surgical technique following local applicable guidelines will be used.~The Maestro Platform may be used to position and hold the scope as well as the retractor in the locations determined by the surgeon during the procedure, with the ability to revert at any time to standard of care (manual minimally invasive surgery) without the usage of the Maestro Platform, or to convert to open surgery.

Intervention type: DEVICE
Intervention: Laparoscopic surgery using the Maestro Platform
Description: Patients scheduled for laparoscopic surgery will be operated on as per standard of care, using standard port, surgical table and instrument placements (following local applicable guidelines), and off-the-shelf surgical equipment. Standard of care surgical technique following local applicable guidelines will be used.~The Maestro Platform may be used to position and hold the scope as well as the retractor in the locations determined by the surgeon during the procedure, with the ability to revert at any time to standard of care (manual minimally invasive surgery) without the usage of the Maestro Platform, or to convert to open surgery.
Study: NCT06589648

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mandala painting
Description: Mandala coloring creates a relaxing effect on individuals because it starts with a pattern that develops like a flower around a point; it allows the individual to stay in the moment, to get away from stress, anxiety and worries, and it relaxes the mind.
Study: NCT06369298

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JK07
Description: JK07 is a fully human anti-human epidermal growth factor receptor 3 (also known as ErbB3 or HER3) antibody fused with the epidermal growth factor (EGF)-domain of Neuregulin (NRG)-1b protein.
Study: NCT06153836

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neurotization Procedure
Description: Undergo placement of nerve graft

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Subcutaneous Mastectomy
Description: Undergo standard of care NSM

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subcutaneous Mastectomy
Description: Undergo standard of care NSM
Study: NCT05335811

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4-[18F]Fluoro-1-Naphthol
Description: By vein (IV)
Study: NCT04905511

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: natural human collagen arteriovenous graft for hemodialysis access
Description: The True Vascular Graft will be implanted in the forearm or upper arm in a straight or curved configuration.
Study: NCT05692414

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Preoperative carbohydrate drink
Description: Allocation will be performed using an alternating weeks scheme. Patients undergoing surgery in the first week will be included in the control group and follow a conventional fasting protocol. However, patients undergoing surgery the following week will be included in the intervention group and take 800 ml of CHO drink on the day before surgery and 400 ml on the surgery day no later than 6 hours before the procedure.
Study: NCT06369298

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JK07
Description: JK07 is a fully human anti-human epidermal growth factor receptor 3 (also known as ErbB3 or HER3) antibody fused with the epidermal growth factor (EGF)-domain of Neuregulin (NRG)-1b protein.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% sodium chloride
Study: NCT06407700

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Brugger's exercise.
Description: Participant was in a high sitting position. An elastic resistance band was be wrapped on each hand of the participant leaving the palm open and instructed to abduct and extend of thumb along with fingers, followed by wrist extension and forearm supination, the participant were instructed to perform scapular retraction with chin tucked in ,shoulder external rotation, elbow extension, shoulder abduction, and extension. Intervention was started from 10 seconds hold to 30 seconds with 2 seconds increment in every session. Rest time was 30 seconds, 4 sets 12 times repetitions.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Brugger's exercise.
Description: Participant was in a high sitting position. An elastic resistance band was be wrapped on each hand of the participant leaving the palm open and instructed to abduct and extend of thumb along with fingers, followed by wrist extension and forearm supination, the participant were instructed to perform scapular retraction with chin tucked in ,shoulder external rotation, elbow extension, shoulder abduction, and extension. Intervention was started from 10 seconds hold to 30 seconds with 2 seconds increment in every session. Rest time was 30 seconds, 4 sets 12 times repetitions.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Kendall Exercise.
Description: Kendall exercises with the frequency 5 sets of consisting of 12 repetitions of postures, each taking 30 seconds,3 times a week for total of 6 weeks.
Study: NCT05666726

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain
Description: Thermal pain

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stress
Description: Stress state induction

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Craving
Description: Snack craving induction

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Frustration
Description: Real effort task

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Negative valence emotion
Description: Passive video watching with emotional valence
Study: NCT06751719

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: core stabilization exercises
Description: The core exercises would be held for 7 to 8 seconds, repeated 10 times, and rest for 3 seconds between repetitions and 1 minute rest between each exercise. These exercises will include:~1. Abdominal hollowing~2. Supine extension bridge~3. Partial Curls

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stabilization exercises
Description: The core exercises would be held for 7 to 8 seconds, repeated 10 times, and rest for 3 seconds between repetitions and 1 minute rest between each exercise. These exercises will include:~1. Abdominal hollowing~2. Supine extension bridge~3. Partial Curls

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: heat therapy
Description: The heat therapy would be applied to the lumbar region for 10 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: heat therapy
Description: The heat therapy would be applied to the lumbar region for 10 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: proprioceptive exercises
Description: The proprioceptive exercises will include rest for 3 seconds between repetitions and 1-minute rest between each exercise. These exercises will include:~1. One leg balance - 10 seconds hold time with 3 repetitions~2. Forward leg swings - 15 swings~3. Sideways leg swings - 15 swings

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: calisthenic exercises
Description: The calisthenic exercises will include:~1. Abductor's leg raise for 10 repetitions~2. Prone leg extension for 10 repetitions~3. Alternate toe touch for 10 repetitions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesthetic exercises
Description: The kinesthetic exercises will have 1 minute rest in between exercises. These exercises will include:~1. Toe walking for 20 meters distance~2. Heel walking for 20 meters distance
Study: NCT06752213

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vagus nerve Stimulation
Description: Vagus nerve Stimulation

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vagus nerve Stimulation
Description: Vagus nerve Stimulation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: Manual therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: Manual therapy
Study: NCT06755021

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whey Protein Milk-Derived Exosomes
Description: WPMDE2 (Whey Protein Milk-Derived Exosomes 2) is an advanced nutritional supplement developed from natural milk components.
Study: NCT06755957

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Description: Posture exercise, stretching exercise, breathing exercise, back strengthening exercise, self-mobilization exercise, cat camel exercise and postural correction exercise will be applied.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CONTROL
Description: Posture exercise, stretching exercise, breathing exercise, back strengthening exercise, self-mobilization exercise, cat camel exercise will be applied.
Study: NCT05102890

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ESOGER
Description: For patients in the intervention group, ESOGER will be administered by phone by a member of the clinic team prior to their virtual or in-persons consultation with their primary care provider. ESOGER is already available on an online platform for data entry. Based on feedback our team obtained from interviews with current users of ESOGER, administration of the tool is expected to take between 5 and 10 minutes. A report summarizing the health and social status of the patient along with flagged potential vulnerabilities will be generated automatically by the online ESOGER platform. This report will then be uploaded to the patient's electronic chart by a member of the clinic and made available for the primary care provider at the time of the consultation.
Study: NCT06548555

Intervention type: OTHER
Intervention: systematic educational intervention
Description: This is a non-interventional study and does not impose a therapy protocol, or a diagnostic/therapeutic procedure. Patients are treated according to the local prescribing information, and routine medical practice in terms of visit frequency and types of assessments performed and only these data is collected as part of the study.
Study: NCT05019430

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cocaine
Description: The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and zolmitriptan.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cocaine
Description: The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and zolmitriptan.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cocaine
Description: The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and zolmitriptan.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cocaine
Description: The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and zolmitriptan.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral capsule
Description: The pharmacodynamic effects of placebo will be determined.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zolmitriptan
Description: The pharmacodynamic effects of zolmitriptan maintenance will be determined.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zolmitriptan
Description: The pharmacodynamic effects of zolmitriptan maintenance will be determined.
Study: NCT05265468

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Jones Group (Strain Counterstrain)
Description: No pain positioning technique with diaphragmatic breathing

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lewit Group
Description: Isometric muscular exercise acompained with stretching technique

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Chaitow Group
Description: Isometric muscular exercise acompained with stretching technique and diaphragmatic breathing

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Group
Description: No pain positioning of participants