TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04087109

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic decision support for deprescribing (MedSafer tool)
Description: During the intervention phase, MedSafer will provide users with individualized and prioritized deprescribing opportunities: a) identifying the medication, b) explaining why that medication is potentially inappropriate and c) providing instructions on how to safely stop/taper the medication. The user will review these opportunities and appropriate candidate medications for deprescribing can then be tapered or stopped directly in the EMR. Patients or proxy will also receive educational medications brochures (EMPOWER) from the research assistant or staff at the nursing home, as applicable to the medications they are taking (PPI, sedative-hypnotic, antipsychotic, antihistamine, sulfonylurea, NSAID, opioid/narcotic).
Study: NCT04445896

Intervention type: OTHER
Intervention: Qualitative Interview
Description: Qualitative Interview to explore thoughts and feelings related to previous discussions around care at end of life
Study: NCT05353153

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hypnosis
Description: Hypnosis-based intervention with two sessions of hypnosis (focusing on the treatment of anxiety)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: standart care
Description: no intervention no hypnosis
Study: NCT05971082

Intervention type: OTHER
Intervention: Follow-up
Description: Follow-up study of progression/remission of liver disease
Study: NCT06516380

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Combined treatment of Cyberdyne HAL single joint with TecnoBody D-Wall and Walker View 3.0 SCX devices
Description: HAL-SJ sessions were conducted 5 days a week for 3 months and 2 hours a day for a total of 60 sessions. HAL-SJ application was performed in cybernic voluntary control (CVC) mode for 90 minutes. In addition to each HAL-SJ session, balance exercises were performed with TecnoBody D-Wall for 30 minutes net.
Study: NCT06088784

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATH-399A
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATH-399A
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATH-399A
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATH-399A
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATH-399A
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Orally administered drug in capsule form.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Orally administered drug in capsule form.
Study: NCT04754048

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Avance Solo NPWT System
Description: Wound treatment with Avance Solo NPWT System for up to 28 days.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Avance Solo NPWT System
Description: Wound treatment with Avance Solo NPWT System for up to 28 days.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Avance Solo NPWT System
Description: Wound treatment with Avance Solo NPWT System for up to 28 days.
Study: NCT06421532

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XYWAV
Description: Daily before bedtime for 3 months

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XYWAV
Description: Daily before bedtime for 3 months

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: gammaCore Sapphire
Description: Twice daily for 3 months

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: gammaCore Sapphire
Description: Twice daily for 3 months
Study: NCT06383533

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab Vedotin Plus Cadonilimab
Description: Disitamab Vedotin: 2.0mg/kg，ivgtt，D1, every 2 weeks for a treatment cycle. Cardonilimab: 6mg/kg，ivgtt，D1, every 2 weeks for a treatment cycle.
Study: NCT05437406

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent-based treatment- All caregivers (PBT-AC)
Description: PBT-AC provides all the elements of FBT, including nutrition and physical activity education, behavior therapy skills, and parenting skills.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Education (HE)
Description: The HE arm will provide information about nutrition, physical activity, sedentary behavior, sleep, emotions, and stress.
Study: NCT05950074

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: It´s Up To You program
Description: The main goal of this program is to prevent substance use and engagement in addictive behaviors through enabling teenagers to make informed and responsible decisions. It seeks to support students in the anticipation of realistic choice situations and problems typically affecting this age group. It is based on social influences, considering the peer group influences (peer pressure) and the affective and cognitive factors that intervene at the time of decision-making and problem-resolution. This program is intended to be delivered by trained teachers in six sessions through six different modules.
Study: NCT00279487

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gabapentin

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebos
Study: NCT06410092

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FTL001
Description: IV infusion every 2 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FTL001
Description: IV infusion every 2 weeks
Study: NCT04663282

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INS068 injection
Description: INS068 injected subcutaneously once daily. Treat-to-target dose titration during the trial

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin Degludec
Description: Insulin Degludec injected subcutaneously once daily. Treat-to-target dose titration during the trial
Study: NCT05394155

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Leucine
Description: 7 intake levels of leucine, ranging from 10 to 75 mg/kg/d.
Study: NCT06020820

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cervical Rehabilitation program (Intervention Group) Group A
Description: (Positional release technique on trapezius muscle): the therapist locate and apply pressure along the tender points in the upper fibers of the trapezius. Lateral flexion of subject's head toward the side of a tender point held for 90 seconds.~(Suboccipital muscle release): The therapist places both his palms under the sub occipital region of the subject with his curled-up fingers and places an upward pressure causing a stretch and distraction for 30 seconds,This technique was performed 3 times in one session.~Stretching of pectoralis muscle:~Pectoralis muscle stretch were performed once daily, completing three repetitions on each side with a 30-second hold. Stretching with repetition of five, three times a day for 1week neck and soulder ROMs

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control group group B
Description: 1. Relax shoulders and neck sufficiently~2. look down~3. turn face to the right~4. turn face to the left~5. incline head to the right~6. incline head to the left~7. turn shoulders round and round~8. slowly raise hands fully then lower them. patients were asked to perform five repetitions of each stretching exercise, three times per day (morning, afternoon, and evening).
Study: NCT06250348

Intervention type: OTHER
Intervention: Non invasive measure of endogenous exhaled Nitric Oxyde in exhaled gaz, by a laser spectrometer
Description: A sample of exhaled gases is taken from the expiratory part of the respirator circuit (same way as a capnometry measurement). A laser spectrometer continuously and non-invasively monitors online the concentrations of endogenous NO exhaled by patients.

Intervention type: OTHER
Intervention: Non invasive measure of endogenous exhaled Nitric Oxyde in exhaled gaz, by a laser spectrometer
Description: A sample of exhaled gases is taken from the expiratory part of the respirator circuit (same way as a capnometry measurement). A laser spectrometer continuously and non-invasively monitors online the concentrations of endogenous NO exhaled by patients.
Study: NCT05586438

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colistin Sulfomethate
Description: The patients receive colistin 150 mg intravenous once daily on non-dialysis day and receive colistin 150 mg intravenous every 12 hours on dialysis day
Study: NCT04871646

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-314+SOC
Description: CKD-314 is administered intravenously and standard of care is also performed.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CKD-314 Placebo+SOC
Description: CKD-314 placebo is administered intravenously and standard of care is also performed..
Study: NCT05386771

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Whey/collagen protein blend
Description: Ingestion of 30g of protein dissolved in 300ml water consumed after an exercise session

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whey/collagen protein blend
Description: Ingestion of 30g of protein dissolved in 300ml water consumed after an exercise session

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Resistance exercise
Description: A single resistance exercise session of the leg press and leg extension exercise

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance exercise
Description: A single resistance exercise session of the leg press and leg extension exercise
Study: NCT05537662

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard of care neuromodulation therapy (SCS or DRG)
Description: Standard SCS or DRG therapy
Study: NCT05174403

Intervention type: OTHER
Intervention: Cerebral and spinal cord magnetic resonance imaging
Description: Cerebral and spinal cord magnetic resonance imaging (without injection of contrast medium).~Patient's data will be compared to calibrated data from the commercially available medical software Brain Quant (licence BT-BQ-001-START, market CAIH, CE12331).
Study: NCT06096961

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baby smell
Description: Mothers in the experimental group will be given baby clothes that their babies will wear for 12 hours and will be asked to smell these clothes during the milking process.
Study: NCT05429008

Intervention type: DRUG
Group type: OTHER
Intervention: HMPL-A83 injection
Description: Day 1,8,15,22 dose; 28 day treatment cycles.
Study: NCT06519604

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human insulin enteric coated capsules in dose 16mg
Description: Single oral administration of human insulin enteric coated capsules in dose 16mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human insulin enteric coated capsules in dose 8mg
Description: Single oral administration of human insulin enteric coated capsules in dose 16mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Human Insulin Injection in dose 5IU
Description: Single subcutaneous administration of Human Insulin Injection in dose 5IU
Study: NCT06012552

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tianeptine
Description: Tianesal 12,5mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: application as in the control group
Study: NCT05064137

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monomeric self - assembling peptide P11-4
Description: Monomeric self - assembling peptide P11-4 ( Curodont Repair ) is a remineralizing agent applied on tooth surface after treating it with 3% sodium hypochlorite for 20 seconds then etching it with 37% phosphoric acid for 20 seconds followed by rinsing then dryness.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tricalcium phosphate fluoride varnish, 5% F-
Description: Tricalcium phosphate fluoride varnish, 5% F- ( Clinpro White Varnish ) is a remineralizing agent applied on tooth surface after mixing it with a brush onto the dosage guide.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: fluoride varnish (5% sodium fluoride)
Description: fluoride varnish (5% sodium fluoride) ( Voco-profluorid ) is a remineralizing agent applied on tooth surface then area is allowed to become wet (either by gentle rinsing or natural salivary flow) to ensure setting of VOCO Profluorid Varnish.
Study: NCT05654818

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: 100,000 UI

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo is identical in appearance to the active treatment: a drinkable solution in ampoules that is clear, yellowish in color with a slightly lemony odor and an oily, slightly sweet, lemony taste.
Study: NCT06379815

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sodium Lactate
Description: See arm/group description.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sodium Chloride
Description: See arm/group description.
Study: NCT05133141

Intervention type: DEVICE
Intervention: Echelon Contour
Description: There is no intervention, beyond necessary clinical care, in this study. Echelon Contour is used for transection and resection in colorectal surgical procedures per its instructions for use (IFU).
Study: NCT06003049

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: OnabotulinumtoxinA
Description: BOTOX injection series

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo injection series
Study: NCT06003894

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kegel exercises
Description: Kegel exercises; It is done by squeezing your pelvic floor muscles for 3 to 5 seconds and relaxing them. Participants are expected to do this exercise in the form of hold-relax 10-15 times each set. Participants are expected to practice Kegel exercises, 2 sets a day, 3 days a week for 8 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: kegel exercises
Description: Kegel exercises; It is done by squeezing your pelvic floor muscles for 3 to 5 seconds and relaxing them. Participants are expected to do this exercise in the form of hold-relax 10-15 times each set. Participants are expected to practice Kegel exercises, 2 sets a day, 3 days a week for 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 360 degree expanded diaphragmatic breathing training
Description: 360-degree expanded diaphragm breathing is the delivery of air taken during inspiration to the postero-lateral wall of the abdomen. Breathing in this way ensures that the pressure in the abdomen is distributed equally in all directions. Practices for using this breathing pattern will be done 2 sets per day, each set for 10 minutes.
Study: NCT05851261

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PA3670
Description: Placebo as control

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PA3670
Description: Placebo as control

Intervention type: DRUG
Group type: OTHER
Intervention: PA3670
Description: Placebo as control

Intervention type: DRUG
Group type: OTHER
Intervention: PA3670
Description: Placebo as control

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PA3670
Description: Placebo as control

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PA3670
Description: Placebo as control
Study: NCT04791332

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-67953964
Description: JNJ-67953964 capsule will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-67953964
Description: JNJ-67953964 capsule will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo will be administered orally.
Study: NCT04221867

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stricture dilation with CRE balloon
Description: Esophageal stricture is treated by dilation therapy.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autologous fat grafting
Description: Autologous fat graft is gathered and injected to stricture
Study: NCT06523920

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: University of Wisconsin solution + cold storage
Description: Preservation of the free flap with UW solution and cold storage during ischemia time

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Unperfused free flap under warm ischemia
Description: Traditional processing of the free flap: no perfusion of the flap and warm ischemia (room temperature conservation during ischemia time
Study: NCT06295484

Intervention type: OTHER
Group type: OTHER
Intervention: Alternating traditional CPAP, NIPPV, and high CPAP
Description: The investigators will continue to record the Edi signals during the 3 methods (traditional CPAP, NIPPV, and high CPAP)

Intervention type: OTHER
Group type: OTHER
Intervention: Alternating traditional CPAP, NIPPV, and high CPAP
Description: The investigators will continue to record the Edi signals during the 3 methods (traditional CPAP, NIPPV, and high CPAP)

Intervention type: OTHER
Group type: OTHER
Intervention: Alternating traditional CPAP, NIPPV, and high CPAP
Description: The investigators will continue to record the Edi signals during the 3 methods (traditional CPAP, NIPPV, and high CPAP)

Intervention type: OTHER
Group type: OTHER
Intervention: Alternating traditional CPAP, NIPPV, and high CPAP
Description: The investigators will continue to record the Edi signals during the 3 methods (traditional CPAP, NIPPV, and high CPAP)

Intervention type: OTHER
Group type: OTHER
Intervention: Alternating traditional CPAP, NIPPV, and high CPAP
Description: The investigators will continue to record the Edi signals during the 3 methods (traditional CPAP, NIPPV, and high CPAP)

Intervention type: OTHER
Group type: OTHER
Intervention: Alternating traditional CPAP, NIPPV, and high CPAP
Description: The investigators will continue to record the Edi signals during the 3 methods (traditional CPAP, NIPPV, and high CPAP)
Study: NCT05355246

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: assisted sit-up exercises
Description: Group A patients will be instructed to perform assisted sit-up exercises by lying on their back and lifting their torso. They will use their body weight to strengthen and tone the core stabilizing abdominal muscles. This exercise will perform a minimum of five and maximum of 10 repetitions, two times a day and two days a week. Isometrics, back stretching, and strengthening exercises will be given as a common intervention for both groups before starting treatment session.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: swiss ball pikes exercises
Description: Group B patients will be instructed to perform swiss ball pikes by getting into the pushup position, the rest of the tops of their feet on a swiss ball. Each patient should keep her legs as straight as possible, bend her hips and try to pull her feet towards their chest so that the ball rolls forward. Hold at the top for three to four seconds, then slowly roll back to the starting position. This exercise will perform a minimum of one or two and a maximum of 10 repetitions, two times a day and two days a week. Both exercises will be performed for 12 weeks in both groups. Isometrics, back stretching, and strengthening exercises will be given as a common intervention for both groups before starting the treatment session.
Study: NCT04840693

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological samples
Description: blood, urine, saliva

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Biological samples
Description: blood, urine, saliva

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological samples
Description: blood, urine, saliva

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological samples
Description: blood, urine, saliva

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Complications
Description: bone mineral density, diabetes, hypertension, quality of life (quality of life questionnaire SF-36)

Intervention type: OTHER
Group type: OTHER
Intervention: Complications
Description: bone mineral density, diabetes, hypertension, quality of life (quality of life questionnaire SF-36)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Complications
Description: bone mineral density, diabetes, hypertension, quality of life (quality of life questionnaire SF-36)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Complications
Description: bone mineral density, diabetes, hypertension, quality of life (quality of life questionnaire SF-36)
Study: NCT05821777

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LB101
Description: Part 1: IV infusion of LB101 Q2W (28-day cycle) and Part 2: IV infusion of LB101
Study: NCT06029829

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: Any first-line treatment that includes immunotherapy、 Chemotherapy and Anti-angiogenesis Therapy
Study: NCT04931706

Intervention type: OTHER
Intervention: Magnetics Assisted by Singe port
Description: Use of magnet for assistance through the surgery, and a novel approach as it is single port
Study: NCT05724888

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer mentorship and physical activity
Description: Participants will be asked to participate for 12 weeks, attending 3 sessions per week (if in the intervention arm). Session 1 will be a group session that will be about 90 minutes, session 2 will be an individual session with a peer mentor for 20-30 minutes, and session 3 will be a virtual check in with the peer mentor about 15 minutes. The intervention will focus on increasing physical activity through the circle of courage.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer mentorship and physical activity
Description: Participants will be asked to participate for 12 weeks, attending 3 sessions per week (if in the intervention arm). Session 1 will be a group session that will be about 90 minutes, session 2 will be an individual session with a peer mentor for 20-30 minutes, and session 3 will be a virtual check in with the peer mentor about 15 minutes. The intervention will focus on increasing physical activity through the circle of courage.
Study: NCT04634253

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3462817
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3462817
Description: Given IV
Study: NCT04308291

Intervention type: DEVICE
Intervention: MiniMed™ 780G System
Description: Subject enrolled in the study will start using the MiniMed™ 780G pump in Auto Mode after a run-in period of two weeks in Manual Mode (with no SmartGuard™ functions). Study phase in Automode will follow a 6 and 12 months follow- up as per standard of care.