TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06674616

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Coaching
Description: Coaching is based on the Positive Behavior Interventions and Supports model, addresses staff barriers by building implementers' evidence-based practice (EBP) knowledge, self-efficacy, and skills through clinical support and feedback.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facilitation
Description: Facilitation addresses potential organizational barriers to delivery, including leadership support and acceptance among other staff.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facilitation
Description: Facilitation addresses potential organizational barriers to delivery, including leadership support and acceptance among other staff.
Study: NCT06674785

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: focused extracorporeal shock wave therapy (ESWT)
Description: The focused shockwaves are directed at the affected muscles in the upper limb, specifically targeting the subscapularis, pectoralis major, latissimus dorsi, and teres major muscles.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: focused extracorporeal shock wave therapy (ESWT)
Description: Placebo shockwave therapy directed at subscapularis, pectoralis major, latissimus dorsi, and teres major muscles.
Study: NCT05627492

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialectical behavioral therapy
Description: DBT will be conducted over 2 years. Participants and their treatment providers will decide on the frequency of sessions collaboratively. This may include individual and/or skills sessions in addition to phone coaching for those who attend individual sessions at least once per month. DBT consultation will also remain a component of the treatment. Participants may choose skills training, conducted in approximately 60 minute meetings, and individual therapy conducted in approximately 60 minute sessions. Family participation in skills training is highly encouraged. Skills training may include: psychoeducation, mindfulness skills, emotion regulation skills, distress tolerance skills, interpersonal skills, and walking the middle path skills. Individual therapy sessions aim to aid the youth in applying skills in their daily lives. We adopt the standard DBT hierarchy of treatment targets.
Study: NCT05414747

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ABV-1701
Description: ABV-1701 is an injectable, in-situ-forming hydrogel, composed of oxidized hyaluronic acid (oxi-HA) and adipic acid dihydrazide (ADH)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SF6 Gas
Description: SF6 is a commercial gas tamponade as a vitreous substitute in pars-plana vitrectomy surgery (PPV)
Study: NCT05743140

Intervention type: DIAGNOSTIC_TEST
Intervention: CaIMR
Description: Investigators diagnose CMD with CaIMR. Investigators use OCT and OCTA to analyze the fundus microcirculation quantitatively.
Study: NCT06686420

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: B. longum
Description: On the first day of the intervention period, participants will be instructed to consume two capsules of the live B. longum strain daily with a glass of water before breakfast for the next eight weeks.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: On the first day of the intervention period, participants will be instructed to consume two capsules, which are without any live bacteria, daily. They should take these before breakfast with a glass of water, for the following eight weeks.
Study: NCT06690931

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Brain-Computer Interface with FES and VR
Description: The intervention utilizes the recoveriX PRO system. This is a neurofeedback therapy device that combines Brain-Computer Interface based motor imagery, functional electrical stimulation (FES), and virtual reality (VR). This approach enables participants to engage in motor imagery exercises while receiving real-time feedback based on neural signals.~Participants will complete a total of 24 recoveriX sessions, scheduled at 6 sessions per week, with each session lasting 1 hour.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Motor imagery with Functional Electrical Stimulation and Virtual Reality feedback
Description: The participants will train the Motor Imagination (MI) combined with Functional Electrical Stimulation (FES) and Virtual Reality (VR) feedback. Feedback provided to the patients will not be linked to the neural signals.~The amount of stimulation delivered by the feedback devices (FES and VR) will be similar to the experimental group.
Study: NCT06689982

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tofacitinib tablets
Description: All patients should be closely monitored for signs and symptoms of infection during and after treatment with tofacitinib tablets. If a patient develops a severe infection, opportunistic infection, or sepsis, medication should be discontinued. During treatment, patients with lymphocyte counts \< 500 cells/mm\^3 or ANC \< 500 cells/mm\^3 confirmed by repeated testing should be stopped. When 500≤ANC≤1000 cells/mm\^3, administration should be interrupted, and if ANC returns to more than 1000 cells/mm\^3, administration should be resumed. When hemoglobin \< 8 g/dL or decreases by more than 2 g/dL, administration should be interrupted until hemoglobin values return to normal.
Study: NCT06689137

Intervention type: OTHER
Intervention: mini mental state assessment test
Description: Anesthesia management during surgery for this disease in the postoperative period should be carefully planned. It will be important to examine the neurocognitive effects of anesthesia management in the postoperative period in this patient group. In this study, the frequently used Mini mental state assessment test and Mini-cog test will be used. With mini mental state assessment, the patient is asked a number of simple questions to evaluate cognitive functions and each question has certain points. Changes in these score levels preoperatively and postoperatively will be compared within each patient. At the end of the study, preoperative and postoperative changes will be compared statistically between the groups.
Study: NCT04946110

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electromagnetic stimulation
Description: Electromagnetic stimulation of the phrenic nerve
Study: NCT05782439

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual evaluation of ITB tension
Description: There will be a double evaluation for each sampling session: 1) if there is a uniformity of the tension between the two sides, or if there is a prevalence on one side; 2) quantification of the difference, if present, with a graduation in 3 levels.
Study: NCT06254560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab is administered at a dose of 100mg per week, a total of 4 times. Cyclosporin is administered at a dose of 3-5mg/kg per day.
Study: NCT06689137

Intervention type: OTHER
Intervention: mini mental state assessment test
Description: Anesthesia management during surgery for this disease in the postoperative period should be carefully planned. It will be important to examine the neurocognitive effects of anesthesia management in the postoperative period in this patient group. In this study, the frequently used Mini mental state assessment test and Mini-cog test will be used. With mini mental state assessment, the patient is asked a number of simple questions to evaluate cognitive functions and each question has certain points. Changes in these score levels preoperatively and postoperatively will be compared within each patient. At the end of the study, preoperative and postoperative changes will be compared statistically between the groups.

Intervention type: OTHER
Intervention: mini-cog test
Description: Anesthesia management during surgery for this disease in the postoperative period should be carefully planned. It will be important to examine the neurocognitive effects of anesthesia management in the postoperative period in this patient group. In this study, the frequently used Mini mental state assessment test and Mini-cog test will be used.With Mini-cog test, the patient is asked a number of simple questions to evaluate cognitive functions and each question has certain points. Changes in these score levels preoperatively and postoperatively will be compared within each patient. At the end of the study, preoperative and postoperative changes will be compared statistically between the groups.
Study: NCT06020430

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: CTV omitted or delineated
Description: Patients who responded to the induction therapy (immunotherapy and chemotherapy) were randomly (1:1) assigned into CTV-omitted radical radiotherapy group or CTV-delineated radiotherapy group.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: CTV omitted or delineated
Description: Patients who responded to the induction therapy (immunotherapy and chemotherapy) were randomly (1:1) assigned into CTV-omitted radical radiotherapy group or CTV-delineated radiotherapy group.
Study: NCT06689137

Intervention type: OTHER
Intervention: mini-cog test
Description: Anesthesia management during surgery for this disease in the postoperative period should be carefully planned. It will be important to examine the neurocognitive effects of anesthesia management in the postoperative period in this patient group. In this study, the frequently used Mini mental state assessment test and Mini-cog test will be used.With Mini-cog test, the patient is asked a number of simple questions to evaluate cognitive functions and each question has certain points. Changes in these score levels preoperatively and postoperatively will be compared within each patient. At the end of the study, preoperative and postoperative changes will be compared statistically between the groups.
Study: NCT06681727

Intervention type: OTHER
Intervention: Accessible Video Mental Healthcare Triage and Assessment (IP)
Description: Patients aged 18 years and older who were registered at participating primary care centers were eligible to access the IP through a regional healthcare app. IP comprised a brief digital screening followed by a 45-minute video consultation with a mental health professional. Eligible patients could thereafter schedule appointments at cooperating healthcare centers and clinics through the app used for video consultations.
Study: NCT06694428

Intervention type: OTHER
Intervention: Reinterpretation of CMV serology results using the MyCMV tool on the basis of the serology results performed
Description: The CMV serology results of the patients will have been previously interpreted as part of the care on the basis of the entire virological file according to the reference method.~These results will be reinterpreted using the MyCMV tool on the basis of the serology results performed (IgM, IgG, avidity), CMV PCR, the date of sampling and the date of the start of pregnancy (or last period). This reinterpretation by the tool will be carried out as part of the study and will not be communicated to the patient or to the doctor prescribing the virological analyses.
Study: NCT05116072

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: total pancreatectomy
Description: The total pancreatectomy will be performed in two steps: The pancreatectomy will begin by a standard pancreaticoduodenectomy procedure.~The section margin will be sent for intraoperative histological analysis to confirm the absence of invasion of the left remnant pancreas.~When absence of tumor invasion is confirmed and the high-risk of postoperative pancreatic fistula is validated intraoperatively, the extended left distal pancreatectomy will be performed, with splenic preservation when possible.~Then, the left side of the pancreas will be resected and cooled (4-6°) in the preservation solution and shipped to Lille Biotherapy platform to perform islet isolation and purification. The reconstruction after total pancreatectomy will be done as usually performed by center expert surgeon.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: intraportal islet autotransplantation
Description: The final islet preparation will be cultured and shipped 48 hours after total pancreatectomy from the Lille laboratory to the surgical center, and finally transplanted into the patient through a venous catheter placed in the portal trunk (91% of the total islet mass) and at the same time, a small fraction of the isolated islet (5% of the total islet mass) will be transplanted into the forearm muscle.
Study: NCT06521099

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evaluative Conditioning with positive stimuli
Description: In the pre-conditioning phase, participants will be exposed to pictures that vary in their emotional (negative, positive) and social (non-social, social) content. For each picture, they are required to indicate their immediate perceived valence (between negative to positive), degree of social engagement (between none to high), experiences of the scenes (never to always) on Likert-scales. In the conditioning phase, the most negative and most positive social pictures perceived by each participant in their pre-conditioning phase will be selected and paired with positive stimuli for trials in random order, for 6 sessions across 3 weeks. In the post-conditioning phase, participants will be asked to evaluate the valence of the stimuli again similar to that in pre-conditioning phase.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conditioning with neutral stimuli
Description: In the pre-conditioning phase, participants will be exposed to pictures that vary in their emotional (negative, positive) and social (non-social, social) content. For each picture, they are required to indicate their immediate perceived valence (between negative to positive), degree of social engagement (between none to high), experiences of the scenes (never to always) on Likert-scales. In the conditioning phase, the most negative and most positive social pictures perceived by each participant in their pre-conditioning phase will be selected and paired with with neutral stimuli for trials in random order, for 6 sessions across 3 weeks. In the post-conditioning phase, participants will be asked to evaluate the valence of the stimuli again similar to that in pre-conditioning phase.
Study: NCT06694688

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: the supine/standing postural change test
Description: The prevalence of orthostatic hypotension will be characterized by the percentage of patients with a decrease of ≥ 20mmHg in systolic blood pressure or ≥ 10mmHg in diastolic blood pressure following the supine/standing postural change position.
Study: NCT06694298

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYS6020
Description: BCMA Chimeric Antigen Receptor T Cell（SYS6020）Injection Intravenous infusion
Study: NCT06688591

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention programme to optimise medication management and prevent MRPs
Description: The intervention is based on a four-step patient empowerment process: 1) the patient understands their role; 2) the patient acquires sufficient knowledge to be able to engage with their healthcare professionals; 3) the patient improves their skills; and 4) there is a facilitating environment (30). Each older adult participant's plan will be unique and consider their preferences, medication literacy and treatment adherence.
Study: NCT06378502

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin Short
Description: Short Span

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin Long
Description: Long span
Study: NCT06694818

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: trauma film paradigm
Description: Use the trauma films as stressors to induce stress and evaluate how it affects sleep reactivity in healthy subjects with insomnia symptoms compared to healthy subjects without insomnia symptoms
Study: NCT06022588

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sodium butyrate, 1-13C, 99%, Cambridge Isotope Laboratories, Inc.USA
Description: a solution containing butyrate of which 12C of the last 4 carbon positions of butyrate were replaced by 13C butyrate. Participants received 0.80 gram 13C-butyrate (7.3 mMol butyrate / 29 mMol 13C) dissolved in 50 mL water at baseline

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium butyrate, 1-13C, 99%, Cambridge Isotope Laboratories, Inc.USA
Description: a solution containing butyrate of which 12C of the last 4 carbon positions of butyrate were replaced by 13C butyrate. Participants received 0.80 gram 13C-butyrate (7.3 mMol butyrate / 29 mMol 13C) dissolved in 50 mL water at baseline
Study: NCT06694818

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: trauma film paradigm
Description: Use the trauma films as stressors to induce stress and evaluate how it affects sleep reactivity in healthy subjects with insomnia symptoms compared to healthy subjects without insomnia symptoms
Study: NCT06695871

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient navigation-based health management
Description: A patient navigation-based health management model for individuals with cervical lesions post-LEEP procedure, encompassing healthcare consultation services, personalized health guidance, and routine follow-up assessments.
Study: NCT06022588

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: U-13C6, 99%; Cambridge Isotope Laboratories, Inc.USA
Description: a glucose solution in which all six 12C carbons were replaced by 13C D-Glucose. Participants received 0.75 gram 13C-glucose (4.2 mMol D-glucose/ 25 mMol 13C) dissolved in 50 mL water at baseline
Study: NCT06695260

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CT scan
Description: CT will be performed when the wrist is under loading compared to normal conditions. scapholunate kinematics will be examines
Study: NCT06694064

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpotomy
Description: Pulpotomy will be done for mta group

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpotomy
Description: Pulpotomy will be done for mta group

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: extraction for histologic examination
Description: after pulp therapy the teeth exrtracted for histologic examination
Study: NCT06022588

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: U-13C6, 99%; Cambridge Isotope Laboratories, Inc.USA
Description: a glucose solution in which all six 12C carbons were replaced by 13C D-Glucose. Participants received 0.75 gram 13C-glucose (4.2 mMol D-glucose/ 25 mMol 13C) dissolved in 50 mL water at baseline

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Breath test
Description: Breath tests were performed at the following time points baseline, 0.5, 1, 1.25 1.5, 1.75, 2, 2.25, 2.5, 3, 3.5 and 4 hours after ingestion of 13C-butyrate and 13C-glucose. Breath samples were obtained by blowing a single breath of air through a straw into a test tube. Two breath samples were collected at all mentioned time points. Measurement of 13CO2 is performed using mass spectrometry (IDMicro Breath, Compact Science Systems, Newcastle-Under-Lyme, United Kingdom) using procedures described earlier for galactose and methacetin breath tests, and expressed as an absolute increase in the 13CO2-to-12CO2 ratio in delta permil (δ‰).

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Exercise + breath test
Description: The intervention groups performed a standardized bicycle ergometer exercise test of 30 minutes and semi-continuous peripheral blood lactate monitoring. The bicycle ergometer protocol consists of three phases. The first 10 minutes of exercise was used to gradually increase the workload until submaximal exercise intensity was reached which is defined as a circulating blood lactate level between 3 and 5.5 mmol/L. From minute 10 to 20 submaximal exercise intensity was maintained by adjusting the workload based on lactate measurements. Minute 20 to 30 was used to reach maximal exercise intensity, the workload was increased by 10% of the submaximal workload until exhaustion
Study: NCT06694064

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: extraction for histologic examination
Description: after pulp therapy the teeth exrtracted for histologic examination
Study: NCT06694805

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAB LA + RPV LA
Description: Intramuscular injection administered monthly for first 2 initiation doses then every 2 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral ART
Description: Oral medication provided to participants by the site/their regular healthcare professional (HCP) as part of their standard of care (SOC) treatment.
Study: NCT06691412

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obeticholic Acid 5 mg
Description: - Patients will be randomly divided into two groups , the first will receive obeticholic acid at a dose of 5 mg once daily and antiviral drug ,and the other will receive the antiviral drug only for six months
Study: NCT06694103

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reverse Kangaroo Care Position
Description: * Babies will be taken to the examination table and their clothes other than diapers will be removed.~* Mothers will take off their upper clothes and lie on the examination table and position their babies in the reverse kangaroo care position, with the baby's back against the mother's bare chest.~* Babies will be monitored with disposable probes from their right feet.~* Video recording will be started. -While the position applied to the babies is maintained, the speculum will be placed in the eye by the ophthalmologist and the examination will be recorded on video from the beginning to end.~* After the completion of both eye examinations, the position of the babies whose monitoring continues will be maintained while the video recording will be taken for another 1 minute. The SPO2, HR, PIPP-R score at the end of the 15th second before the examination, the first minute during the examination and the 30th second after the examination will be evaluated.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ROP Position
Description: * Babies will be taken to the examination table and monitored with disposable probes from their right feet.~* The nurse will place the infant's own palms on the temporal region and hold them with her hands to support their head, while the mother will also support the infant by holding their legs.~* The video recording will be started.~* SPO2, HR, PIPP-R values will be recorded on video for one minute.~* While the ROP position applied to the babies is maintained, the speculum is placed in the eye by the ophthalmologist and the examination begins.~* SPO2, HR, PIPP-R evaluation at the 1st minute of the examination.~* After the completion of both eye examinations, the babies whose monitoring continues will be kept in their positions and a video recording will be taken for another 1 minute.~* The SPO2, HR values and PIPP-R pain score at the end of the 30 seconds after the examination will be evaluated.