TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05842096

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Measurement and comparison of leucocytosis and concentrations of CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha in both study arms
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare the above parameters of peripheral blood in both arms of the study

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Measurement and comparison of leucocytosis and concentrations of CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha in both study arms
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare the above parameters of peripheral blood in both arms of the study

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the impact of subclinical hypothyroidism, with present/ absent antithyroid antibodies, on the balance between anti- and pro-inflammatory factors in women in both study arms
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare blood levels of leukocytosis, CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha depending on the blood concentrations of TSH, a-TPO and a-TG in women in both study arms

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the impact of subclinical hypothyroidism, with present/ absent antithyroid antibodies, on the balance between anti- and pro-inflammatory factors in women in both study arms
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare blood levels of leukocytosis, CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha depending on the blood concentrations of TSH, a-TPO and a-TG in women in both study arms

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Assessment of the impact of imbalance between anti- and pro-inflammatory factors in women with different PCOS and HPOD phenotypes on ovarian reserve indices
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare blood levels of leukocytosis, CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha and AMH, FSH in women in both study arms

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Assessment of the impact of imbalance between anti- and pro-inflammatory factors in women with different PCOS and HPOD phenotypes on ovarian reserve indices
Description: A venous blood sample of approximately 10 ml will be collected in the morning after 8 hours of fasting to determine and compare blood levels of leukocytosis, CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha and AMH, FSH in women in both study arms
Study: NCT05181436

Intervention type: DIAGNOSTIC_TEST
Intervention: measuring Total Haemoglobin (SpHb) using Masimo Rad-67.
Description: To determine the prevalence of Malaysian children aged ≥ 6 to ≤ 36 months at risk of anaemia by measuring Total Haemoglobin (SpHb) using Masimo Rad-67.
Study: NCT05442476

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotaping
Description: For the KT application, participants will be asked to stand with keeping their feet at shoulder level in a comfortable manner. The patient will be in a standing position with lumbar spine flexion. A 5 cm wide long I-shaped piece of tape will be applied with 80% tension transverse to the patient's painful area and the bilateral SIJ region, with no tension applied to the ends of the tape. Another short piece of tape will be applied with 80% tension at an angle from the painful point to the hip, and no tension will be applied to the ends of the tape. An identical application will be performed on the other side of the sacroiliac region

Intervention type: OTHER
Group type: OTHER
Intervention: Muscle Energy Technique
Description: The subject will be asked for the sitting on the treatment table, back towards the therapist. Then the subject will be taken into flexion, rotation and side bending. When the subject will reach the tolerated limit of flexion, the therapist will ask him to perform extension, sidebending and rotation to the opposite side while holding the breath for 7-10 seconds and rest for 2-3 seconds, then the patient will be asked to release the breath. The therapist will wait for the participant's full exhalation and then will take her further in all the directions of restriction, towards the new barrier. MET will be performed for 10 repetitions.

Intervention type: OTHER
Group type: OTHER
Intervention: conventional physiotherapy
Description: conventional physiotherapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physiotherapy
Description: conventional physiotherapy
Study: NCT06107881

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low Vision Rehabilitation
Description: Evaluation and training with magnification or visual assistive devices for visually-impaired adults

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Low Vision Rehabilitation
Description: Evaluation and training with magnification or visual assistive devices for visually-impaired adults
Study: NCT06023017

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prone Position Training
Description: All patients were admitted to our hospital at least 3 days before surgery. Patients in the intervention group (PPT group) received the prone position training daily in the hospital, three times a day, and about 1 hours every times, for at least 3 days before surgery. On the day of admission to the hospital, the patients in the PPT group were instructed to perform prone position training by nurses who were previously trained by prone position training.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: standard perioperative care without any prone position training
Description: Patients in the control group (C group) received standard perioperative care without any prone position training.
Study: NCT05796375

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cystoscopy
Description: Cystoscopy entails direct inspection of the bladder via a cystoscope that is inserted into a patient's urethra.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cystoscopy
Description: Cystoscopy entails direct inspection of the bladder via a cystoscope that is inserted into a patient's urethra.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cystoscopy
Description: Cystoscopy entails direct inspection of the bladder via a cystoscope that is inserted into a patient's urethra.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Bladder EpiCheck urine test
Description: The Bladder EpiCheck is a laboratory-developed test for early-stage non-muscle invasive bladder cancer. The Bladder EpiCheck test is a DNA methylation test that is run on DNA extracted from cell pellet from centrifuged urine according to Standardized Operating Procedures. The test has internal controls and a dedicated software to ensure required quality assurance processes and prompt reporting of results.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Xpert Bladder Cancer Monitor urine test
Description: A 4.5 ml sample of voided urine is added to Xpert® Urine Transport Reagent, mixed, and then 4ml of treated urine are transferred to the Sample Chamber of the cartridge. In the cartridge, cells in the urine sample are captured on a filter and lysed by sonication. The released nucleic acid is eluted, mixed with dry RT-PCR reagents, and the solution is transferred to the reaction tube for RT-PCR and detection.
Study: NCT05185713

Intervention type: OTHER
Intervention: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.
Description: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.

Intervention type: OTHER
Intervention: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.
Description: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.

Intervention type: OTHER
Intervention: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.
Description: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.

Intervention type: OTHER
Intervention: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.
Description: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.

Intervention type: OTHER
Intervention: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.
Description: This project is a clinical observational study. No additional medication or surgical interventions are performed on the subjects.
Study: NCT04561765

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iCanCope
Description: The iCanCope mobile and web-based self-management program has been empirically evaluated for multiple painful diseases

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iCanCope+Contingency Management
Description: In addition to the iCanCope-NF activities outlined above, individuals will be rewarded with incentives (contingency management) such as points that are redeemable for prize-based gift card vouchers. Points will be accrued through access to new sections, daily check-ins, and engagement of the mobile application. Based on research, the total amount of money that can be earned by the patient over the course of the two months is 50 dollars USD.
Study: NCT05270252

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Learning and Care
Description: The educational intervention lasted 10 hours: six face-to-face and four for personal study. Three educational methodologies were combined.~The first: flipped classroom. Students received training material in their email: articles on the needs of families / cancer survivors and family nursing according to the Calgary Model (Wright \& Leahey, 2013) and experiential videos of survivors and family members. In the classroom, a week later, a nurse promoted students' self-learning and reflection.~The second: simulation clinical case. The students received by email a summary of the case and material for their personal work. Students in groups of three performed the entire clinical scenario.~The third: round table. The components were advanced practice nurse, medical oncologist, cancer survivor and a family member. The content revolved around personal experience in caring for family members and cancer survivors and the interdisciplinary work required for this care.
Study: NCT04433988

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline
Description: Pentoxifylline 400 mg SR tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet
Study: NCT05765578

Intervention type: BIOLOGICAL
Intervention: Moderna COVID-19 Vaccine
Description: Sterile liquid for injection. Intervention not administered through this study.

Intervention type: BIOLOGICAL
Intervention: Moderna mRNA1273.222 Booster
Description: Sterile liquid for injection. Intervention not administered through this study.

Intervention type: BIOLOGICAL
Intervention: Pfizer COVID-19 Vaccine
Description: Sterile liquid for injection. Intervention not administered through this study.

Intervention type: BIOLOGICAL
Intervention: Moderna 2023 Updated COVID-19 vaccine (XBB.1.5)
Description: Sterile liquid for injection. Intervention not administered through this study.

Intervention type: BIOLOGICAL
Intervention: Pfizer 2023 Updated COVID-19 vaccine (XBB.1.5)
Description: Sterile liquid for injection. Intervention not administered through this study.
Study: NCT06532149

Intervention type: DRUG
Intervention: Alectinib
Description: Alectinib 600 mg/BID

Intervention type: DRUG
Intervention: Brigatinib
Description: 180 mg/daily

Intervention type: DRUG
Intervention: Lorlatinib 100 mg
Description: 100 mg/daily

Intervention type: DRUG
Intervention: Osimertinib
Description: 80 mg/daily

Intervention type: DRUG
Intervention: Sotorasib
Description: 960 mg/daily

Intervention type: DRUG
Intervention: Dabrafenib
Description: 150 mg/BID

Intervention type: DRUG
Intervention: Trametinib
Description: 2 mg/daily

Intervention type: DRUG
Intervention: Selpercatinib
Description: 160 mg/BID

Intervention type: DRUG
Intervention: Pembrolizumab
Description: 200 mg intravenous every 21 days

Intervention type: DRUG
Intervention: Pembrolizumab
Description: 200 mg intravenous every 21 days

Intervention type: DRUG
Intervention: Cemiplimab
Description: 350 mg intravenous every 21 days

Intervention type: DRUG
Intervention: Cemiplimab
Description: 350 mg intravenous every 21 days

Intervention type: DRUG
Intervention: Nivolumab
Description: 240 mg intravenous every 14 days

Intervention type: DRUG
Intervention: Nivolumab
Description: 240 mg intravenous every 14 days

Intervention type: DRUG
Intervention: Carboplatin
Description: AUC4/AU5 intravenous every 21 days

Intervention type: DRUG
Intervention: Pemetrexed
Description: 500 mg/mq intravenous every 21 days

Intervention type: DRUG
Intervention: Paclitaxel
Description: 175 mg/mq intravenous every 21 days
Study: NCT06413082

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Torasemide
Description: The assignment to each drug will be carried out randomly in each genotypic group with the aim of reaching the same number of patients treated with the two drugs in the different genotypic groups

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spironolactone
Description: The assignment to each drug will be carried out randomly in each genotypic group with the aim of reaching the same number of patients treated with the two drugs in the different genotypic groups
Study: NCT04995224

Intervention type: OTHER
Intervention: Assessment of Psychophysiological factors
Description: Investigating the presence of psychophysiological factors (depression, anxiety, catastrophizing) by questionnaires.

Intervention type: OTHER
Intervention: Assessment of Psychophysiological factors
Description: Investigating the presence of psychophysiological factors (depression, anxiety, catastrophizing) by questionnaires.

Intervention type: OTHER
Intervention: Assessment of Psychophysiological factors
Description: Investigating the presence of psychophysiological factors (depression, anxiety, catastrophizing) by questionnaires.

Intervention type: OTHER
Intervention: Assessment of Psychophysiological factors
Description: Investigating the presence of psychophysiological factors (depression, anxiety, catastrophizing) by questionnaires.

Intervention type: BIOLOGICAL
Intervention: Assessment of Biological factors
Description: Investigating autonomic nervous function using heart rate recording, colon biopsy samples, microbiota, and blood cytokines levels. (Colon biopsy samples are obtained when colonoscopy is performed for clinical reasons. Blood samples and stool samples will be taken when participants come to the hospital for colonoscopy)

Intervention type: GENETIC
Intervention: Assessment of Genetics
Description: Genetic data investigated by another cohort study (IBD BioResource study) will be utilized in the analysis of this study.

Intervention type: GENETIC
Intervention: Assessment of Genetics
Description: Genetic data investigated by another cohort study (IBD BioResource study) will be utilized in the analysis of this study.

Intervention type: GENETIC
Intervention: Assessment of Genetics
Description: Genetic data investigated by another cohort study (IBD BioResource study) will be utilized in the analysis of this study.

Intervention type: GENETIC
Intervention: Assessment of Genetics
Description: Genetic data investigated by another cohort study (IBD BioResource study) will be utilized in the analysis of this study.

Intervention type: BEHAVIORAL
Intervention: Assessment of Quality of Life
Description: Investigating QOL by questionnaires.

Intervention type: BEHAVIORAL
Intervention: Assessment of Quality of Life
Description: Investigating QOL by questionnaires.

Intervention type: BEHAVIORAL
Intervention: Assessment of Quality of Life
Description: Investigating QOL by questionnaires.

Intervention type: BEHAVIORAL
Intervention: Assessment of Quality of Life
Description: Investigating QOL by questionnaires.

Intervention type: BIOLOGICAL
Intervention: Assessment of Biological factors
Description: Investigating colon biopsy samples (Colon biopsy samples are obtained when colonoscopy is performed for clinical reasons).
Study: NCT05211843

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Drinking water
Description: The intervention will compare the effects of a usual serving of drinking water with the effects of a usual serving of apple juice. Both beverages will also be assessed relative to the effects of not drinking anything at all.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple juice
Description: apple juice
Study: NCT05107726

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TRE Group
Description: This group will practice time-restricted eating
Study: NCT06230211

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music Therapy
Description: Effect of Maternal Voice and Music Therapy on Pain and Physiological Parameters During the Suction Procedure in Intubated Children: Randomized Controlled Study

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maternal Voice
Description: Effect of Maternal Voice and Music Therapy on Pain and Physiological Parameters During the Suction Procedure in Intubated Children: Randomized Controlled Study
Study: NCT06071689

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: screw retained prosthesis
Description: all-on-4 screw-retained prosthesis.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: screw retained prosthesis
Description: all-on-4 screw-retained prosthesis.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: screw retained prosthesis
Description: all-on-4 screw-retained prosthesis.
Study: NCT05688475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CC-122
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Specified dose on specified days
Study: NCT04558840

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Macromastia
Description: Patients with macromastia seeing the principle investigator (PI) (JMK) at his office at the Outpatient Building, which includes the Outpatient Surgery Center (OSC), in the Department of Plastic Surgery clinic at UT-Southwestern for their initial operative consultation for reduction mammaplasty will be offered enrollment in the trial if they are deemed appropriate surgical candidates, based on the PI's clinical judgement and expertise.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Macromastia
Description: Patients with macromastia seeing the principle investigator (PI) (JMK) at his office at the Outpatient Building, which includes the Outpatient Surgery Center (OSC), in the Department of Plastic Surgery clinic at UT-Southwestern for their initial operative consultation for reduction mammaplasty will be offered enrollment in the trial if they are deemed appropriate surgical candidates, based on the PI's clinical judgement and expertise.
Study: NCT05611190

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CT-FFR
Description: CT-FFR is a type of non-invasive procedure to provide a 3D model of coronary arteries as a way to evaluate the hemodynamic significance of coronary artery lesions. CT-FFR calculates FFR from subject-specific CCTA data using computational fluid dynamics technology. CT-FFR value ≤0.80 is considered hemodynamically significant.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Usual Care
Description: Participants randomized to usual care will be evaluated according to institutional standard practice.
Study: NCT06005207

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: progesterone vaginal sustained-release gel
Description: 90 mg progesterone vaginal sustained-release gel is added daily during endometrial transformation and luteal support
Study: NCT03995953

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SHIELD intervention (Support for HIV Integrated Education, Linkages to care, and Destigmatization)
Description: The SHIELD intervention includes a three-session, six-module program for AGYW that increases knowledge, skills, and self-efficacy to engage along the HIV prevention and care continuum, and a two-session, four-module program for family members to increase social support. In addition, the SHIELD intervention includes youth clubs to foster peer support.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SHIELD intervention (Support for HIV Integrated Education, Linkages to care, and Destigmatization)
Description: The SHIELD intervention includes a three-session, six-module program for AGYW that increases knowledge, skills, and self-efficacy to engage along the HIV prevention and care continuum, and a two-session, four-module program for family members to increase social support. In addition, the SHIELD intervention includes youth clubs to foster peer support.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated wellness care (IWC) clinics
Description: IWC clinics will be created within health facilities where AGYWs can receive sexual and reproductive health services, including HIV testing and treatment, family planning, sexually transmitted disease screening and treatment, and HPV vaccination in a youth-friendly environment.
Study: NCT04845503

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MR-guided Radiotherapy
Description: Total Dose 37,5 Gy, Single Dose 7,5 Gy, 5 Fractions applied in 1-2 weeks
Study: NCT05731063

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Computer guided simultaneous implant placement with tri-cortical ridge augmentation using chin cortical bone struts
Description: fabrication of surgical guide to aid in chin bone harvesting and another guide to help for accurate placement and simultaneous placement in anterior maxillary defective area.
Study: NCT05366738

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Orally via tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Orally via tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Orally via tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Orally via sprinkle pellets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Orally via sprinkle pellets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Orally via sprinkle pellets
Study: NCT05814172

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention