TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05862415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: therapeutic Exercise
Description: The circular training method was used in the resistance training phase. During the aerobic training phase, a series of movements from moderate intensity to vigorous intensity was performed. The step loading periodization principle was taken into account in both resistance training and aerobic exercises.~The RT lasted approximately 20-25 min per session and included two sets of 8-20 repetitions, with a rest interval of 1-2 min. The RT exercises included: squat, barbell bent-over row, overhead press, plank, lateral pull down, triceps push down, barbell curl, leg extension, leg curl, lunge, barbell bench press, crunches etc.~For the aerobic training: Intensity was established between 50-65% and 80-85% of HRmax for both groups (SAG and ASG). Aerobic training includes walking and running periods and was carried out on a 400 m outdoor track. In periodization, especially 1st-4th.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: therapeutic Exercise
Description: The circular training method was used in the resistance training phase. During the aerobic training phase, a series of movements from moderate intensity to vigorous intensity was performed. The step loading periodization principle was taken into account in both resistance training and aerobic exercises.~The RT lasted approximately 20-25 min per session and included two sets of 8-20 repetitions, with a rest interval of 1-2 min. The RT exercises included: squat, barbell bent-over row, overhead press, plank, lateral pull down, triceps push down, barbell curl, leg extension, leg curl, lunge, barbell bench press, crunches etc.~For the aerobic training: Intensity was established between 50-65% and 80-85% of HRmax for both groups (SAG and ASG). Aerobic training includes walking and running periods and was carried out on a 400 m outdoor track. In periodization, especially 1st-4th.
Study: NCT05081973

Intervention type: OTHER
Intervention: A model for predicting extubation success based on extubation readiness estimator and lung ultrasonography score
Description: Parameters to be recorded before and after extubation to create a new dual extubation model from all babies who met the extubation criteria included in the study:~1. Lung ultrasound score: Lung ultrasound will be performed prior to the extubation and after the extubation. Lung aeration will be scored based on three chest areas for each side (upper anterior, lower anterior and lateral) and a score of 0 to 3 points will be given for each area (Total score ranges from 0 to 18 points).~2. Probability of Successful Extubation: It will be calculated by extubation readiness estimator provided by the website named http://extubation.net/.~This parameter will be calculated only 1 hour prior to the scheduled extubation time.
Study: NCT05632328

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN1423
Description: via IV, dosage per protocol, once every 2 weeks for up to 8 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botensilimab
Description: via IV, dosage per protocol, once evert 2 weeks, up to 2 years

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botensilimab
Description: via IV, dosage per protocol, once evert 2 weeks, up to 2 years

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: per standard care

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab-paclitaxel
Description: per standard care
Study: NCT04810026

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: Healthy-lifestyle and diabetes-related virtual education (text and videos)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Healthy-lifestyle and diabetes-related virtual education (text and videos)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Healthy-lifestyle and diabetes-related virtual education (text and videos)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meal delivery
Description: breakfast, lunch, and dinner adhering to the longevity diet macro-nutrient profiles

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meal delivery
Description: breakfast, lunch, and dinner adhering to the longevity diet macro-nutrient profiles

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle coaching
Description: calls with coach and/or nutritionist, access to Facebook community support group
Study: NCT04949711

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ridesharing voucher
Description: Ridesharing vouchers will be given for completing each of the online surveys, for a possible total of $80 if you complete all three surveys. You will be paid with electronic vouchers that will be sent to your cell phone.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: online shopping voucher
Description: Online shopping vouchers will be given for completing each of the online surveys, for a possible total of $80 if you complete all three surveys. You will be paid with electronic vouchers that will be sent to your cell phone.
Study: NCT06296082

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Botulinum toxin type A
Description: Botulinum toxin type A injections are a treatment technique to treat the spastic muscles in patients with stroke that targets on the neuromuscular endplate zone provoking a chimical disruption of dysfunctional endplates.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dry Needling
Description: Dry Needling is a treatment technique to treat the spastic muscles in patients with stroke that targets on the neuromuscular endplate zone provoking a mechanical disruption of dysfunctional endplates.
Study: NCT05435794

Intervention type: DEVICE
Intervention: CPAP
Description: Fixed-pressure CPAP device for the treatment of sleep apnea with optional humidification and heated circuit. This device is a Class II device. It has a remote monitoring function allowing service providers to track the use of the device.

Intervention type: DEVICE
Intervention: MAD
Description: mandibular device orthosis made to measure from the dental impressions of patients, made by the specialist in the masticatory apparatus for the treatment of sleep apnea.
Study: NCT05960994

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention period
Description: During the intervention period, three interventions will be implemented through telemedicine.~1. A daily multidisciplinary round conducted by a physician specialized in intensive care medicine.~2. A intervention package administered by a specialized multidisciplinary team, consisting of nursing, physiotherapy, and clinical pharmacy.~3. A management intervention package will be implemented, with a specific focus on enhancing quality and safety.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention period
Description: During the intervention period, three interventions will be implemented through telemedicine.~1. A daily multidisciplinary round conducted by a physician specialized in intensive care medicine.~2. A intervention package administered by a specialized multidisciplinary team, consisting of nursing, physiotherapy, and clinical pharmacy.~3. A management intervention package will be implemented, with a specific focus on enhancing quality and safety.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention period
Description: During the intervention period, three interventions will be implemented through telemedicine.~1. A daily multidisciplinary round conducted by a physician specialized in intensive care medicine.~2. A intervention package administered by a specialized multidisciplinary team, consisting of nursing, physiotherapy, and clinical pharmacy.~3. A management intervention package will be implemented, with a specific focus on enhancing quality and safety.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention period
Description: During the intervention period, three interventions will be implemented through telemedicine.~1. A daily multidisciplinary round conducted by a physician specialized in intensive care medicine.~2. A intervention package administered by a specialized multidisciplinary team, consisting of nursing, physiotherapy, and clinical pharmacy.~3. A management intervention package will be implemented, with a specific focus on enhancing quality and safety.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention period
Description: During the intervention period, three interventions will be implemented through telemedicine.~1. A daily multidisciplinary round conducted by a physician specialized in intensive care medicine.~2. A intervention package administered by a specialized multidisciplinary team, consisting of nursing, physiotherapy, and clinical pharmacy.~3. A management intervention package will be implemented, with a specific focus on enhancing quality and safety.
Study: NCT05915715

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: McGill stabilization exercise
Description: McGill Curl Up Lie down on your back.~The Side Bridge Lie on your side.~The Bird Dog.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Proprioceptive neuromuscular facilitation technique
Description: . The patient is in sitting position and faces the physical therapist. The RST program consisted of alternating (trunk flexion-extension) isometric contractions against resistance for 10 seconds, with no motion intended. Subjects performed 3 sets of 15 repetitions at maximal resistance provided by the same physical therapist. Rest intervals of 30 seconds and 60 seconds were provided after the completion of 15 repetitions for each pattern and between sets, respectively.
Study: NCT04732624

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral Rehydration Solution
Description: Feasibility study of Enteral-based resuscitation with Oral Rehydration Solution (ORS) vs standard-of-care Intravenous Fluid resuscitation for moderate-sized burn injuries in Nepal

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lactated Ringer
Description: Standard-of-care Intravenous Fluid resuscitation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactated Ringer
Description: Standard-of-care Intravenous Fluid resuscitation
Study: NCT04584385

Intervention type: DIAGNOSTIC_TEST
Intervention: EEG
Description: EEG monitoring
Study: NCT04396782

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physioterapy rehabilitation with IVR
Description: This program includes: static bicycle with virtual reality glasses, analytical lower limb exercises, global lower limb exerciseswith virtual reality glasses and activities to be done at home.
Study: NCT04774913

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Chronic total occlusion(CTO) percutaneous coronary intervention (PCI)
Description: CTO PCI completed as a two step procedure with an initial planned CTO modification and a completion procedure after 8-12 weeks
Study: NCT04396782

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: standard physiotherapy rehabilitation
Description: static bicycle, analytical lower limb exercises, global lower limb exercises and activities to be done at home.~This group will perform only five minutes of virtual reality play, but will not use their lower limbs. This way, the results of rehabilitation will not be affected and therapists and patients will be blinded.
Study: NCT05125874

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant SARS-CoV-2 Fusion Protein Vaccine
Description: The product should be a milky-white suspension for injection. For prevention of SARS-CoV-2 infection.
Study: NCT04839679

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally Oriented Educational Brochure
Description: Culturally appropriate educational brochure summarizing pertinent treatment information in a visual manner

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mayo Clinic Educational Booklet
Description: An Introduction to Radiation Simulation and Treatment- Barbara Woodward Lips, Patient Education Center

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mayo Clinic Educational Booklet
Description: An Introduction to Radiation Simulation and Treatment- Barbara Woodward Lips, Patient Education Center
Study: NCT04826692

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Metformin oral: 425 mg twice daily (initial dose) and 850 twice daily (maximum dose)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 425 mg twice daily (initial dose) and 850 twice daily (maximum dose)
Study: NCT06370286

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: concurrent exercise (CE)
Description: Participants in the concurrent exercise group engaged in 12-minutes of aerobic exercise (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: aerobic exercise (AE)
Description: Participants in the aerobic exercise (AE) group participated in 25 minutes of AE (40%-59% of heart rate reserve \[HRR\]). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.
Study: NCT03915418

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Connected tools
Description: At home, parents will record their child's sleep for 1night Then, on the date scheduled for the inclusion of the children and after the recording of the 1 night at home, the child will spend a night in a hospital environment to carry out the recording by polysomnography and tools connected simultaneously.
Study: NCT04865393

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPR206
Description: SPR206 100 mg single-dose IV infused over 1 hour
Study: NCT05803174

Intervention type: DIAGNOSTIC_TEST
Intervention: blood sample
Description: Blood collection Circulating serum concentrations of melatonin and dopamine were determined from fasting blood samples. Participants were required to fast from 10 pm the previous evening. A 5 mL serum blood sample was collected from the antecubital vein between 8.30 am and 10 am.~Tear collection Tear samples were collected using Schirmer's strip without anesthesia between 8:30-10:00am. Tears were extracted in 200 μl of 1 X Phosphate Buffered Saline with 0.1% Tween-20 (PBST).~Saliva collection Saliva samples were collected via the passive drool method with subjects in a seated position. Subjects were asked to rinse their mouth with water 10 minutes prior to saliva collection and to refrain from using lip makeup during the sampling period.

Intervention type: DIAGNOSTIC_TEST
Intervention: blood sample
Description: Blood collection Circulating serum concentrations of melatonin and dopamine were determined from fasting blood samples. Participants were required to fast from 10 pm the previous evening. A 5 mL serum blood sample was collected from the antecubital vein between 8.30 am and 10 am.~Tear collection Tear samples were collected using Schirmer's strip without anesthesia between 8:30-10:00am. Tears were extracted in 200 μl of 1 X Phosphate Buffered Saline with 0.1% Tween-20 (PBST).~Saliva collection Saliva samples were collected via the passive drool method with subjects in a seated position. Subjects were asked to rinse their mouth with water 10 minutes prior to saliva collection and to refrain from using lip makeup during the sampling period.

Intervention type: DIAGNOSTIC_TEST
Intervention: blood sample
Description: Blood collection Circulating serum concentrations of melatonin and dopamine were determined from fasting blood samples. Participants were required to fast from 10 pm the previous evening. A 5 mL serum blood sample was collected from the antecubital vein between 8.30 am and 10 am.~Tear collection Tear samples were collected using Schirmer's strip without anesthesia between 8:30-10:00am. Tears were extracted in 200 μl of 1 X Phosphate Buffered Saline with 0.1% Tween-20 (PBST).~Saliva collection Saliva samples were collected via the passive drool method with subjects in a seated position. Subjects were asked to rinse their mouth with water 10 minutes prior to saliva collection and to refrain from using lip makeup during the sampling period.
Study: NCT05713851

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: dapagliflozin is given for 21 days vs standard of care

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dapagliflozin
Description: dapagliflozin is given for 21 days vs standard of care
Study: NCT04791878

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesenchymal stem cells
Description: Direct injection of 75 million allogeneic bone marrow derived mesenchymal stem cells at baseline and again after 3 months if not completely healed
Study: NCT05860205

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Multiple Component Mobile-Aid Pain Reduction Intervention
Description: 1.Posture training through the wearable device, UPRIGHT GO. The participant wears the device on their neck. The device provides biofeedback to poor posture with vibrations and tracks posture. 2. A daily core muscle training and stretching exercise program including trunk rotation, lumbar rotation, hip flexor stretch, side plank, glute bridge, suitcase carry, and palloff press. 3. Participants will practice stress reduction through breath focus which will help them to concentrate on deep breathing to help them ignore distracting thoughts and sensations. 4. Strategies to improve daily level of activity including wearing a Garmin device that tracks their daily physical activity and reminds them to walk and the use of the communication principle to assist participants in overcoming barriers to physical activity.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Multiple Component Mobile-Aid Pain Reduction Intervention
Description: 1.Posture training through the wearable device, UPRIGHT GO. The participant wears the device on their neck. The device provides biofeedback to poor posture with vibrations and tracks posture. 2. A daily core muscle training and stretching exercise program including trunk rotation, lumbar rotation, hip flexor stretch, side plank, glute bridge, suitcase carry, and palloff press. 3. Participants will practice stress reduction through breath focus which will help them to concentrate on deep breathing to help them ignore distracting thoughts and sensations. 4. Strategies to improve daily level of activity including wearing a Garmin device that tracks their daily physical activity and reminds them to walk and the use of the communication principle to assist participants in overcoming barriers to physical activity.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Osteopathic Manipulation Treatment
Description: Osteopathic Manipulation Treatment (OMT) will be conducted by putting pressure on certain muscles in the back and performing OMT exercises on the patient. The physician will treat participants with OMT twice during month 1 and once during month 2 and 3.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sham Osteopathic Manipulation
Description: The sham osteopathic manipulation treatment (OMT) will be performed by the medical team. Hands will be placed on the patient as if the OMT is being performed. The physician will treat participants with sham OMT twice during month 1 and once during month 2 and 3.
Study: NCT05528549

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The investigators are looking at how blood flow and blood pressure are regulated in individuals with Down syndrome, who have a reduced ability to do work. This study will compare individuals with Down syndrome to a control group without Down syndrome.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The investigators are looking at how blood flow and blood pressure are regulated in individuals with Down syndrome, who have a reduced ability to do work. This study will compare individuals with Down syndrome to a control group without Down syndrome.
Study: NCT05268302

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dengue 4 Live Virus Human Challenge (DENV-4-LVHC) - Low Dose
Description: Low dose 0.5 mL of the challenge strain is administered subcutaneously in the triceps region of the arm on Study Day 0.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dengue 4 Live Virus Human Challenge (DENV-4-LVHC) - Medium Dose
Description: Medium dose 0.5 mL of the challenge strain is administered subcutaneously in the triceps region of the arm on Study Day 0.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dengue 4 Live Virus Human Challenge (DENV-4-LVHC) - High Dose
Description: High dose 0.5 mL of the challenge strain is administered subcutaneously in the triceps region of the arm on Study Day 0.
Study: NCT04929847

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-prepared emollient
Description: The emollient is hypo-allergenic, free of perfume and has very high hydrating capacities together with antioxidants.
Study: NCT05597904

Intervention type: GENETIC
Intervention: Genetic predisposition
Description: Assessment of genetic predisposition to various celiac disease phenotypes. No intervention.

Intervention type: GENETIC
Intervention: Genetic predisposition
Description: Assessment of genetic predisposition to various celiac disease phenotypes. No intervention.
Study: NCT05912218

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MEI6570
Description: Saline Control

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: MEI6570
Description: Saline Control
Study: NCT04884165

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Remote monitoring of home mechanical ventilation (NIV) using SRETT
Description: Patients will use the SRETT device attached to their home ventilator.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home mechanical ventilation (NIV) without remote monitoring
Description: Usual care
Study: NCT06518772

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hot application
Description: The application procedure started with the application of hot gel packets at a temperature of 40-42°C to the soles of the feet of the women in the intervention group for 20 minutes when cervical dilation reaches 5 cm.