TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05297591

Intervention type: OTHER
Intervention: assessment of UL function and prognostic factors
Description: clinical assessments and questionnaires
Study: NCT06648603

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community-based larval source management
Description: This project will foster active engagement with community stakeholders, including healthcare workers, community leaders, and other key informants, through participatory meetings aimed at co-creating and developing larval source reduction measures tailored to community's needs. This method emphasizes a participatory framework, ensuring that interventions are both community-informed and culturally relevant.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Enhanced Aedes adults trapping (BG-GAT)
Description: Furthermore, the project intends to determine whether the addition of cost-effective, gravid female mosquito-targeting traps, specifically two Biogents Gravid Aedes Traps (BG-GAT) per household, can improve the overall success of these community-based intervention.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Community-based larval source management with Enhanced Aedes adults trapping (BG-GAT)
Description: The community-based interventions and the BG-GAT deployment will be evaluated in combination to assess their individual and synergistic effects on vector control. This dual strategy combines local participation and practical, evidence-based solutions to address mosquito-borne illness transmission.
Study: NCT06109714

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Goal Directed Fluid Therapy
Description: Fluid administration and hemodynamic management guided with the assistance of Edwards Lifesciences ACUMEN monitor
Study: NCT04647448

Intervention type: DIAGNOSTIC_TEST
Intervention: Application of sensor patch
Description: Application of sensor patch to chest to record acoustic signals due to disturbed blood flow.

Intervention type: DIAGNOSTIC_TEST
Intervention: Application of sensor patch
Description: Application of sensor patch to chest to record acoustic signals due to disturbed blood flow.
Study: NCT06126484

Intervention type: PROCEDURE
Group type: OTHER
Intervention: transcatheter cardiac intervention
Description: Balloon atrial septostomy, PDA stent implantation, Pulmonary valvuloplasty, Aortic valvuloplasty, Balloon angioplasty of coarctation, PDA closure in preterm neonates
Study: NCT06187545

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Minimum viable prototype
Description: Deep sedation in critical ill patients using minimum viable prototype

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Deep sedation without minimum viable prototype
Study: NCT05058677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: instilled 2% lidocaine solution
Description: The instilled 2 % lidocaine solution used will be 1.5 mg/kg, with a max volume of 3 ml or adjusted to a volume of 3 ml with addition of NS solution.The instilled solution will be given with a standard 3-5 ml syringe.After each treatment a 3-minute interval will be allowed prior to ETS and there will be a 4-6 hour wash out period between each treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: instilled 2% lidocaine solution
Description: The instilled 2 % lidocaine solution used will be 1.5 mg/kg, with a max volume of 3 ml or adjusted to a volume of 3 ml with addition of NS solution.The instilled solution will be given with a standard 3-5 ml syringe.After each treatment a 3-minute interval will be allowed prior to ETS and there will be a 4-6 hour wash out period between each treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: instilled 2% lidocaine solution
Description: The instilled 2 % lidocaine solution used will be 1.5 mg/kg, with a max volume of 3 ml or adjusted to a volume of 3 ml with addition of NS solution.The instilled solution will be given with a standard 3-5 ml syringe.After each treatment a 3-minute interval will be allowed prior to ETS and there will be a 4-6 hour wash out period between each treatment.
Study: NCT04751591

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic resection
Description: Endoscopic submucosal dissection (ESD) or endoscopic full-thickness resection (EFTR) for patients with 2-5cm gastric GISTs
Study: NCT05058677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: instilled 2% lidocaine solution
Description: The instilled 2 % lidocaine solution used will be 1.5 mg/kg, with a max volume of 3 ml or adjusted to a volume of 3 ml with addition of NS solution.The instilled solution will be given with a standard 3-5 ml syringe.After each treatment a 3-minute interval will be allowed prior to ETS and there will be a 4-6 hour wash out period between each treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: instilled 2% lidocaine solution
Description: The instilled 2 % lidocaine solution used will be 1.5 mg/kg, with a max volume of 3 ml or adjusted to a volume of 3 ml with addition of NS solution.The instilled solution will be given with a standard 3-5 ml syringe.After each treatment a 3-minute interval will be allowed prior to ETS and there will be a 4-6 hour wash out period between each treatment.
Study: NCT04963400

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of hs-cTnT serum concentration at hospitalization
Description: Analysis of the hs-cTnT serum concentration in the blood drawn at the day of hospitalization

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of hs-cTnT serum concentration at hospitalization
Description: Analysis of the hs-cTnT serum concentration in the blood drawn at the day of hospitalization

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of hs-cTnT serum concentration at hospitalization
Description: Analysis of the hs-cTnT serum concentration in the blood drawn at the day of hospitalization

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of hs-cTnT serum concentration after discharge
Description: Analysis of the hs-cTnT serum concentration in the blood drawn after discharge (60 days after hospitalization)

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of hs-cTnT serum concentration after discharge
Description: Analysis of the hs-cTnT serum concentration in the blood drawn after discharge (60 days after hospitalization)
Study: NCT05058677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: instilled 2% lidocaine solution
Description: The instilled 2 % lidocaine solution used will be 1.5 mg/kg, with a max volume of 3 ml or adjusted to a volume of 3 ml with addition of NS solution.The instilled solution will be given with a standard 3-5 ml syringe.After each treatment a 3-minute interval will be allowed prior to ETS and there will be a 4-6 hour wash out period between each treatment.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Suctioning (ETS)
Description: ETS will be performed in a single pass using a closed-system suctioning. Suction will be applied only on withdrawal of the catheter and fraction of inspired oxygen (FIO2) will remain at 100% for 60 seconds following suctioning and then returned to the preprocedural level (baseline).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Suctioning (ETS)
Description: ETS will be performed in a single pass using a closed-system suctioning. Suction will be applied only on withdrawal of the catheter and fraction of inspired oxygen (FIO2) will remain at 100% for 60 seconds following suctioning and then returned to the preprocedural level (baseline).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Suctioning (ETS)
Description: ETS will be performed in a single pass using a closed-system suctioning. Suction will be applied only on withdrawal of the catheter and fraction of inspired oxygen (FIO2) will remain at 100% for 60 seconds following suctioning and then returned to the preprocedural level (baseline).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Suctioning (ETS)
Description: ETS will be performed in a single pass using a closed-system suctioning. Suction will be applied only on withdrawal of the catheter and fraction of inspired oxygen (FIO2) will remain at 100% for 60 seconds following suctioning and then returned to the preprocedural level (baseline).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Suctioning (ETS)
Description: ETS will be performed in a single pass using a closed-system suctioning. Suction will be applied only on withdrawal of the catheter and fraction of inspired oxygen (FIO2) will remain at 100% for 60 seconds following suctioning and then returned to the preprocedural level (baseline).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Suctioning (ETS)
Description: ETS will be performed in a single pass using a closed-system suctioning. Suction will be applied only on withdrawal of the catheter and fraction of inspired oxygen (FIO2) will remain at 100% for 60 seconds following suctioning and then returned to the preprocedural level (baseline).
Study: NCT06650449

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile App-Based Mental Health Support
Description: This intervention uses a mobile application designed to deliver Cognitive Behavioral Therapy (CBT) techniques. The app provides 12 weekly tasks aimed at reducing emotional distress and depressive symptoms in healthcare workers. Tasks include exercises on emotional regulation, coping strategies, and mindfulness. Participants receive notifications to encourage task completion, and the app tracks progress over the 3-month period. At the start and end of the study, participants will complete the PHQ-9 and GHQ-12 questionnaires to assess their mental health status.
Study: NCT04751591

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Laparoscopic partial gastrectomy
Description: Laparoscopic partial gastrectomy for patients with 2-5cm gastric GISTs
Study: NCT06651801

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group Medical Visits
Description: Group medical visits occur every 2 weeks virtually (via Zoom) for 6 months. Each group consists of 45 minutes of group time and 5 minute individual check-in appointments. The group time consists of psychoeducation, group support, and medication follow-up.
Study: NCT06652022

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Systematic therapy combined with radiotherapy
Description: Systematic medical therapy is same as the systematic treatment group. SBRT radiotherapy or conventional fractionated radiotherapy can be used according to the extent and size of the metastatic foci. SBRT radiotherapy is preferred, and a higher dose should be given as far as possible when the normal tissues permit, with a preferred single dose of ≥5Gy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Systematic drug treatment
Description: The choice of first-line treatment is based on the guidelines, and may include chemotherapy or immune checkpoint inhibitors, or a combination of therapies. For patients who can tolerate cisplatin, chemotherapy is given with the gemcitabine-cisplatin regimen, as follows: gemcitabine 1000mg/m2 d1,8; cisplatin 70 mg/m2, avoiding light, intravenous drip d2; 3 weeks for 1 cycle. For intolerant patients, the gemcitabine-carboplatin regimen is given as follows: gemcitabine 1000 mg/m2 d1,8, IV, carboplatin (4.5×\[GFR+25\]) mg, IV, d1; 3 weeks as 1 cycle. Immune checkpoint inhibitors and targeted agents may be administered if the patient does not tolerate chemotherapy; either in combination with chemotherapy or directly as first line.
Study: NCT05603000

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Focused Family Therapy
Description: The Emotion Focused Family Therapy (EFFT) intervention for this study will be delivered to groups of four to ten parents over six weekly sessions of two hours each. The goal of EFFT is to teach and empower parents to coach their child to process the emotions at the source of their mental health symptoms, to increase their child's adaptive behaviours, and to repair emotional injuries within the parent-child relationship. EFFT also targets parents' own emotional challenges that may prevent them from feeling capable or being able to support their child's treatment.~Each EFFT session will include introductions, psychoeducation about emotion and psychopathology, introduction of skills, experiential activities (e.g., chair work), open discussion and feedback, and homework activities covering the foci of EFFT: emotion coaching, behaviour coaching, therapeutic apology, and parental emotion blocks.
Study: NCT04963400

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of hs-cTnT serum concentration after discharge
Description: Analysis of the hs-cTnT serum concentration in the blood drawn after discharge (60 days after hospitalization)
Study: NCT05385783

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CYB003
Description: CYB003 is a synthetic psilocybin analog.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CYB003
Description: CYB003 is a synthetic psilocybin analog.
Study: NCT05477784

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: Receive EC-PC program

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Informational Intervention
Description: Receive education booklet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT06279377

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stabilization Exercises
Description: * Stabilizer Pressure Biofeedback device will be used in deep neck flexors training. Once the starting level is determined, training will be carried out with 2 mmHg pressure increases until the target value is 30 mmHg.~* During the exercises performed with the elastic resistance band, the patient will be asked to move the band with his hands (neck extension, right-left lateral flexion).~* During the exercises with the elastic ball, you will be asked to press your head on the ball at 90 degree angles (in 4 positions).~* Exercises will be performed in 10 repetitions by maintaining muscle contraction for 10 seconds. Exercises will be performed as 1 set of 10 repetitions or 2 sets of 10 repetitions, depending on the patient's tolerance. When 2 sets are completed successfully, the color of the elastic resistance band or the level of the exercise will be changed and continued.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Exercises
Description: * Cervical flexion, extension, lateral flexion and rotation movements will be performed within the scope of the warm-up and cool-down program. Cervical movements will be limited to approximately 30 degrees in the early period.~* As posture exercises, you will be asked to do scapular retraction and turning your shoulders forward and backward. In addition to these movements, pectoral stretching, anterior and posterior capsule stretching exercises will be performed.~* Elastic resistance bands will be used during neck exercises. Patients will be asked to perform cervical flexion, extension and right-left lateral flexion movements against the fixed band.~* Patients will be asked to continue each exercise for 10 seconds. Exercises will be performed as 1 set of 10 repetitions or 2 sets of 10 repetitions, depending on the patient's tolerance. When 2 sets are completed successfully, the elastic resistance band color will be changed and the exercise will progress.
Study: NCT05171673

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Licart™ (diclofenac epolamine) topical system
Description: The Licart™ (diclofenac epolamine) topical system was designed to deliver the nonsteroidal anti-inflammatory drug (NSAID) diclofenac to the site of a minor soft tissue injury through topical application. This investigational product (IP) is a 10 cm x 14 cm topical system comprised of an adhesive material containing 1.3% diclofenac epolamine that is bound to a non-woven polyester felt backing and covered with a polypropylene film release liner. The release liner is removed prior to topical application to the skin.
Study: NCT05385783

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CYB003
Description: CYB003 is a synthetic psilocybin analog.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CYB003
Description: CYB003 is a synthetic psilocybin analog.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CYB003
Description: CYB003 is a synthetic psilocybin analog.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychotherapy
Description: Manualized psychotherapy (called EMBARK) performed by facilitators

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Psychotherapy
Description: Manualized psychotherapy (called EMBARK) performed by facilitators
Study: NCT06260800

Intervention type: OTHER
Intervention: Validation CEQ
Description: In initial assessment, EQ-5D-5L and HADS questionnaires were completed. After sessions 1 and 2, CEQ and WAI-S were filled. Finally, EQ-5D-5L was completed before the fourth session.
Study: NCT05385783

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological Support
Description: Manualized psychological support performed by facilitators

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Psychological Support
Description: Manualized psychological support performed by facilitators
Study: NCT06706141

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PowerPoint presentation.
Description: The training included topics such as breast anatomy; breast cancer incidence in Somalia, mortality, morbidity rates; breast cancer risk factors, importance of screening methods; The messages on breast self-examination, health belief models, breast cancer awareness, confidence for BSE, and perceived barriers/benefits for BSE were presented in a PowerPoint presentation. The procedure for performing breast self-examination was described using the English edition of Bristol-Myers Squibb Oncology. In the movie, BSE was made simpler with schematics showing the breast area that needed to be covered. Simple directions on which fingers to use and how to move them over the breast were provided. After the film, the emphasis shifted to helping students gain more self-assurance in their ability to accurately complete each BSE step. Students were encouraged to use proper palpation technique to find lumps by performing a breast examination on a silicone breast model.
Study: NCT05385783

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological Support
Description: Manualized psychological support performed by facilitators
Study: NCT06725979

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: maxillary expansion using hyrax expander
Description: The rapid expansion of the upper jaw will be performed using palatal expander with hyrax screw, which will be activated 2x a day, until the needed width is reached (according to the cast analysis).
Study: NCT06725173

Intervention type: GENETIC
Intervention: Targeted Long-read sequencing
Description: All patient's will undergo targeted long-read sequencing to resolve genomic and epigenomic signatures of the RB1 gene
Study: NCT06726434

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical neurotomy (SN)
Description: Surgical neurotomy will be performed under general anesthesia according to the previous description. Muscle relaxant drugs will not be used in order to prevent any interference with the intraoperative electrical stimulation.~The patient will be placed in a prone position and a vertical cutaneous incision will be made at the popliteal fossa location.~The tibial nerve will be dissected and the motor nerve branches of the soleus, gastrocnemius, tibialis posterior and flexor hallucis longus will be identified with intraoperative tripolar electrical stimulation. The selected motor nerve branches will be partially sectioned over a 5mm length under the microscope. The extent of nerve section will be determined according to the degree of spasticity and to the intraoperative residual muscular contraction under electrical stimulation

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryoneurotomy (CN)
Description: After the use of an aseptic technique with 2% chlorhexidine, betadine application and a local anesthesia with lidocaine 1% (3ml), percutaneous cryoneurotomy will be performed with METRUM CRYOFLEX device guided by ultrasound with 1.2mm cryoprobe at -89°C placed through a #16 angio guide. Electrical stimulation will be performed to confirm tibial nerve contact at 0.8 mV.~The ice ball will be repositioned to two spots along the nerve. Each lesion will be treated for 2min cryoneurolysis at -89°C, followed by 2min without freezing (passive defreezing period) and 2min of cryoneurolysis at -89°C, based on cryotherapy for pain management.
Study: NCT06725810

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: enadustat
Description: Patients are administered with enarodustat with dosage adjusted according to hemoglobin levels to achieve and maintain hemoglobin target over 96 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: enadustat
Description: Patients are administered with enarodustat with dosage adjusted according to hemoglobin levels to achieve and maintain hemoglobin target over 96 weeks.
Study: NCT06725693

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F/68Ga-Exendin 4
Description: Each subject receive a single intravenous injection of 68Ga/18F-Exendin 4, and undergo PET/CT imaging within the specificed time.
Study: NCT06727409

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Finerenone
Description: Finerenone 10mg or 20 mg as tolerated on top of maximal tolerated RASi and stable SGLT2i therapy
Study: NCT06727045

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mandala Coloring
Description: A literature review was conducted to determine the frequency and number of mandalas to be applied to the patients in the intervention group, and the average of the number of mandala sessions applied to different patient groups was obtained, and mandala application was performed during a total of eight hemodialysis sessions, every other day. Mandala painting was performed approximately 30 minutes after the start of HD treatment, considering the art therapist's recommendation and the symptoms that may develop during HD. Each mandala painting was performed with a structured and different mandala pattern. Since it was stated that the use of round patterns instead of square patterns was effective in increasing the comfort level, the booklet called Mandala Booklet, consisting of 8 structured mandala patterns with round shapes and containing general information about mandala, was used in the study. The group was informed about the content of the booklet face to face. Dry pencils were prefer
Study: NCT06726447

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Artificial Intelligence Tool
Description: The intervention in this study consists of the implementation of an artificial intelligence tool for clinical registration during outpatient consultations. This technology facilitates the documentation of interactions in real time, optimizing the workflow of professionals and enabling more patient-centered care.