TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05053672

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ReOxy
Description: ReOxy therapy is a protocol which employs passive (the patient is at rest), short (up to 10 min) mild normobaric hypoxic exposures alternated with similar duration intervals of breathing hyperoxia (up to 5 min). The gas mixtures are supplied to a patient via facial mask on continued measuring of oxygenation status of the patients, lasting about 45 min in total per treatment session.~The hypoxic load will be individually adjusted, based on the results of a preliminary hypoxic test. The patient inhales air with low oxygen content (10-14%) at atmospheric pressure in a continuous mode through a mask withing 10-min.~During the ReOxy - treatment session, the software automatically adjusts the gas mixture switching, based on changes in physiological parameters (blood oxygen saturation and heart rate) in response to hypoxic and hyperoxic impact (biofeedback control).

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham ReOxy
Description: Placebo treatment with 'sham' ambient air breathing to simulate ReOxy-therapy sessions. Placebo-mode breathing set visually similar to standard breathing set but have a mask with open intake valve. The masks are chosen in a way to provide maximum degree of similarity to reduce the risk of unblinding on the patient-side.
Study: NCT06135662

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CAF + CTG
Description: Surgical techniques for mandibular gingival recession: coronally advanced flap + connective tissue graft. Participants undergo initial evaluations, including periodontal exams and digital imaging, followed by standardized pre-operative preparations. Post-surgery, uniform care includes pain management and oral hygiene instructions, with follow-ups to monitor healing and assess outcomes. Primary and secondary outcomes, like root coverage and patient-reported satisfaction, are consistently measured across groups. Standardized data collection and analysis procedures ensure reliable, comparable results, facilitating an effective comparison of the surgical methods' efficacy.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tunnel Technique + CTG
Description: Surgical techniques for mandibular gingival recession: tunnel technique + connective tissue graft. Participants undergo initial evaluations, including periodontal exams and digital imaging, followed by standardized pre-operative preparations. Post-surgery, uniform care includes pain management and oral hygiene instructions, with follow-ups to monitor healing and assess outcomes. Primary and secondary outcomes, like root coverage and patient-reported satisfaction, are consistently measured across groups. Standardized data collection and analysis procedures ensure reliable, comparable results, facilitating an effective comparison of the surgical methods' efficacy.
Study: NCT05120362

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cream containing JAK Inhibitor
Description: The study drug is a cream containing JAK Inhibitor.
Study: NCT04681859

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Flow Nasal Oxygen (HFNO) treatment
Description: Administration of High Flow Nasal Oxygen (HFNO) to patients who did not respond to standard low-flow oxygen therapy (non-rebreather mask on 15L/min). Adjust flow-rate and FiO2 as per standard HFNO treatment protocol.
Study: NCT05069051

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belimumab 200 MG/ML [Benlysta]
Description: Patients obtain belimumab treatment in combination with rituximab and venetoclax

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard of care
Description: Patients obtain the standard of care: combination rituximab and venetoclax
Study: NCT04681859

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous Positive Airway Pressure (CPAP) therapy using OxyJet
Description: Administer CPAP to patients who did not respond to standard low-flow oxygen therapy (non-rebreather mask on 15L/min). CPAP initiated with FiO2 at 40% and a 10cm PEEP. Titrate PEEP to 15 cm if required. Deliver additional oxygen via secondary port if a higher FiO2 is required.
Study: NCT06342817

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: online mindfulness based meditation program
Description: Participants in the intervention group will attend 8 weekly online meetings lasting approximately 60 minutes each (generally structured in an initial 10 minutes for questions about the practices, 15-20 minutes of exposition on the central theme of the meeting, 5-10 minutes for class practice, 10-15 minutes for post-practice inquiry, 5 minutes for explanation of the week's informal practice and audios for daily practice). Audio in mp3 of the practice carried out at each meeting will be provided to maintain daily individual practice during the week. An online questionnaire related to weekly practices will also be left at the beginning of each meeting.
Study: NCT05055024

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mazindol
Description: Drug: NLS-2
Study: NCT05173883

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: injection ，CU-20401
Description: Subcutaneous injection，cohort A 6 sites

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: injection ，CU-20401
Description: Subcutaneous injection，cohort A 6 sites

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: injection ，CU-20401
Description: Subcutaneous injection，cohort A 6 sites
Study: NCT04852185

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vi-TT
Description: Single-dose V-TT administered to children and adolescents between the ages of 9 months to 15 years.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: MCV-A vaccine
Description: Single-dose of MCV-A vaccine (a meningococcal vaccine)
Study: NCT06232135

Intervention type: OTHER
Intervention: CBCT scan
Description: analysis of the CBCT scan to assign a calcification stage to the subject's lower left third molar and accordingly calculate the estimated age of each subject

Intervention type: OTHER
Intervention: CBCT scan
Description: analysis of the CBCT scan to assign a calcification stage to the subject's lower left third molar and accordingly calculate the estimated age of each subject
Study: NCT05661825

Intervention type: OTHER
Intervention: phase II cardiac rehabilitation
Description: Phase II cardiac rehabilitation was provided in the the department of physical medicine and rehabilitation in Wan Fang Hospital. The programs are two times a week, one session for 30 minutes (30 sessions in total). The training programs are focused on aerobic training with bicycles. The training intensity is calculated with 40% to 80% oxygen consumption reserve from the result of cardiopulmonary exercise test. In case of safety, heart rate, blood pressure, EKG and rate of perceived exertion will be monitored during training.
Study: NCT06142448

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cueing app
Description: All participants that are included come to the movement lab for the baseline measurement. The baseline measurement consists out of extensive clinimetrics (for example MDS-UPDRS) to identify patient characteristics. With the use of an objective gait assessment, the effectiveness of both internal and external cueing is determined. This will divide the participants in three groups; responders, non-responders and in between. Participants who clearly respond to either internal or external cueing (determined as the responders) are asked to apply the working form of cueing in daily life during the six-month follow-up. During this period the participants will use a mobile application that can provide them with a rhythmic auditory stimulus and records the use of this application.~After 6 months, both the responders and non-responders are asked to return to the lab for the follow up measurement in which the baseline measurement is repeated to evaluate the effect of long-term cueing.
Study: NCT05857163

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifasutenizol capsules
Description: 400 mg, BID

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rabeprazole sodium enteric-coated tablets
Description: 20 mg, BID
Study: NCT05242107

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Omega-3 supplement group
Description: 35 Neonates were given Omega 3 in a dose of 40mg/kg/day (8), after establishment of full-feeding and for 2 weeks duration. Omega-300 (Montana pharmaceutical industry) capsule was used which contains 1000mg Omega 3 fatty acids.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Full feeding without receiving any supplementation group
Description: 35 full term Growth Restriction( IUGR) neonates who were followed up to full feeding without receiving any supplementation.
Study: NCT05173883

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: injection ，placebo
Description: Subcutaneous injection，just one site
Study: NCT05857163

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rabeprazole sodium enteric-coated tablets
Description: 20 mg, BID

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin Capsules
Description: 1 g, BID
Study: NCT05748067

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HVGIC restoration
Description: High viscosity glass ionomer restoration

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SSC
Description: Stainless steel crown

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SSC
Description: Stainless steel crown

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SSC
Description: Stainless steel crown
Study: NCT06494475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GBS-NN/NN2 vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GBS-NN/NN2 vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GBS-NN/NN2 vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GBS-NN/NN2 vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tdap vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tdap vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tdap vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tdap vaccine
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intramuscular injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intramuscular injection.
Study: NCT05054140

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMU-838
Description: IMU-838 tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo matching IMU-838
Description: Placebo matching IMU-838 tablets
Study: NCT05698277

Intervention type: DIAGNOSTIC_TEST
Intervention: Automated fetal cardiac function evaluation
Description: Evaluation of ultrasound parameters by automated algorithms.~Ultrasound assessed parameters are:~1. Pulsed wave Doppler Modified Left and Right Myocardial performance indices~2. Spatio-temporal image correlation Tricuspid, Mitral and Septal Annular Plane Systolic Excursion
Study: NCT06494475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intramuscular injection.
Study: NCT05533619

Intervention type: DRUG
Intervention: Proton pump inhibitor
Description: Inpatients using proton pump inhibitor

Intervention type: DRUG
Intervention: Proton pump inhibitor
Description: Inpatients using proton pump inhibitor
Study: NCT05116501

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Whole-exome sequencing
Description: Whole Exome Sequencing (WES), as a comprehensive genetic test, will be used to identify changes in a patient's DNA that are causative or related to patient's low VWF levels.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Whole-exome sequencing
Description: Whole Exome Sequencing (WES), as a comprehensive genetic test, will be used to identify changes in a patient's DNA that are causative or related to patient's low VWF levels.
Study: NCT05857163

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin Capsules
Description: 1 g, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clarithromycin placebo tablets
Description: BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bismuth potassium citrate placebo capsules
Description: BID

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clarithromycin tablets
Description: 500 mg, BID

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bismuth potassium citrate capsules
Description: 240 mg, BID
Study: NCT06540807

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Colovac Colorectal Anastomosis Protection Device
Description: A removable, temporary intraluminal bypass device designed to safely postpone the creation of a protective stoma until 10 days after surgery for only patients who need it (do not have a healed anastomosis)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stoma creation
Description: Diverting loop ileostomy
Study: NCT05639894

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candiate formulation 1
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candiate formulation 1
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candiate formulation 1
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candiate formulation 1
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candidate formulation 2
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candidate formulation 2
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candidate formulation 2
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV vaccine candidate formulation 2
Description: Pharmaceutical Form: Liquid frozen solution in a vial Route of Administration: Intramuscular injection
Study: NCT05695599

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Whole body vibration training
Description: 3 times per week of 20 to 30 minute sessions during 16 weeks of training
Study: NCT05639894

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical Form: Liquid Route of Administration: Intramuscular injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical Form: Liquid Route of Administration: Intramuscular injection
Study: NCT05193578

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Semaglutide, 1.34 mg/mL
Description: Semaglutide, 1.34 mg/mL

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Semaglutide-Placebo
Study: NCT04643106

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hemostatic agent (EVICEL®) application during laparoscopic ovarian cystectomy
Description: During laparoscopic ovarian cystectomy, bleeding will be controlled by using a hemostatic agent (EVICEL®)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: suturing with barbed sutures during laparoscopic ovarian cystectomy
Description: During laparoscopic ovarian cystectomy, suturing of ovarian inner surface will be conducted to stop bleeding
Study: NCT06078046

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mind-body interventions
Description: Parallel randomized controlled trial
Study: NCT05919953

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Immersive virtual reality neck exercises targeting relaxation, mobility, control, and speed of movement, using the Pico G2 4K headset.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Therapeutic education
Description: Several brochures will be given to participants. These brochures will cover the general principles of pain, the persistence of pain, tips for managing chronic non-specific pain, and the use of immersive virtual reality in the rehabilitation of chronic non-specific neck pain.~The information provided in the brochures will be discussed with the physiotherapist during the teleconsultations in order to individualize the therapeutic education.
Study: NCT06628219

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Symani Surgical System
Description: The Symani Surgical System (Symani) is designed for open microsurgery procedures, featuring articulated and interchangeable instruments.
Study: NCT06707337

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Brief Self-compassion Program
Description: Brief Self-compassion Program will be held in a face-to-face hospital environment for the patients with colorectal cancer in the experimental group. This training program has been developed based on the concepts of Mindfulness-Based Compassionate Living and Mindfulness-Based Stress Reduction Programs. The content and topics of the sessions in the program are arranged according to the conceptual structure and flow of the mindfulness-based model. The training program was created in a certain flow, based on the introduction to a short self-compassion program (1 sessions), the importance of self-compassion and self-care in the cancer experience (1 sessions), a self-compassionate approach to challenging emotions and situations (1 sessions). There are 3 sessions in the program and the frequency of sessions is 3 times a week, and each session lasts approximately 45 minutes. The training program will be applied to 33 patients with colorectal cancer in the experimental group.
Study: NCT06727448

Intervention type: OTHER
Intervention: SRQ questionnaire
Description: SRQ questionnaire administered at inclusion visit and 14 days after inclusion
Study: NCT06727019

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low-level red-light
Description: 650-nm low-level red-light

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atropine (0.01%)
Description: Atropine eye drops at concentration of 0.01%
Study: NCT05128201

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: consolidative radiotherapy
Description: local consolidative radiotherapy for all metastatic lesion (30-45Gy/3-8F)
Study: NCT06545019

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Informative Video on Perioperative Anxiety and Maternal Satisfaction
Description: An informative video designed to address potential sources of perioperative anxiety and dissatisfaction during elective lower segment caesarean section under spinal anaesthesia. The video provides details about the procedure, expected sensations, and management of discomfort to enhance patient understanding and reduce anxiety. It is administered to the intervention group of patients scheduled for elective caesarean section, allowing them to view it on their personal devices before the surgery.
Study: NCT05599178

Intervention type: OTHER
Intervention: Ultrasound examination in early labor
Description: Combined trans-abdominal and trans-perineal ultrasound examination
Study: NCT06116292

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The mobile application ESTOI for Asthmatic patients
Description: The mobile application ESTOI have various sections that can be managed and customized by the researchers to meet each patient's needs:~1. SYMPTOM CONTROL, it will record the ACT, TAI, the number of exacerbations, weight, and, depending on the case, symptom control for comorbidities.~2. RECOMMENDATIONS, it will provide patients with information needed to understand their condition, how to control it, and what to do in case of worsening symptoms.~3. YOUR TREATMENT, it will display personalized and update information about the patient's current asthma medication, including dosages and frequencies. There will be explanatory videos on how to administer the therapy and includes an action plan.~4. PEAK FLOW, the patient can record measurements using a Peak Flow Meter at home.~5. NUTRITIONAL PLAN, it will provide a daily dietary guide to enable individuals to adapt these tools and recommendations to their specific needs.~6. MESSAGING, it is a bidirectional contact area.
Study: NCT06627894

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Therapist-Assisted Internet Cognitive-Behavioral Therapy for Depression
Description: Good Days Ahead (MindStreet, Inc.)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Control
Description: Depression education, symptom monitoring, and standard depression care
Study: NCT06429891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-FDG
Description: All study participants will undergo one 18F-FDG PET/CT scan.
Study: NCT06701084

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genomic Sequencing
Description: Genomic sequencing data will be comprehensively analyzed for pathogenic variants that explain the participants epilepsy.
Study: NCT06701513

Intervention type: DRUG
Intervention: Deucravacitinib
Description: As prescribed by treating clinician
Study: NCT06701916

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention group.
Description: The intervention will be carried out by a multidisciplinary team composed of nurses, doctors, social workers, and psychologists from each hospital. Through this intervention, a narrative from the patients will be obtained regarding their goals, desires, capabilities, and resources related to their health situation. A health plan will be jointly created, reflecting both short- and long-term objectives, identifying the resources available to the person and within their immediate environment, and outlining how they want and expect to receive support from healthcare professionals.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care for the outpatient management of Chronic Heart Failure.
Study: NCT06357208

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing Control and Retention
Description: 4 appointments with training of Breathing Control and Retention