TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06012474

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Power breath plus
Description: Power breath plus use a variable load calibrated spring. It can be adjusted from the lowest load setting (17cmH2O) when training began and increased as the patient breathing muscles adapt and become stronger (maximum load setting 274cmH2O). Use a comfortable chair, preferably straight-back so that the spine is straight at all times during the exercise. patients will be instructed to exhale calmly, followed by a maximal forced inspiration to total lung capacity using a mouthpiece and a nasal clip as an aid to prevent air leaks and will ask to make 10 breaths for 3 sets once daily for 7 days with 2min rest between sets

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Incrementing the training load
Description: The resistance will be increased incrementally, based on the rate of perceived exertion (RPE) scored by the patient on the modified Borg Scale. If the RPE is less than 5, the resistance of the inspiratory trainer will be increased incrementally by 2cmH2O. The resistance will not change if the level of perceived exertion is rated from 6 to 8, and the resistance will be decreased by 1 to 2 cmH2O if the level of perceived exertion is rated 9 or 10.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diaphragmatic breathing exercises
Description: Training by using incentive spirometer:~* Loosen any tight clothing, especially around neck.~* Each patient will be instructed to sit upright with placing incentive spirometer at the same level of his mouth to promote optimal lung expansion while using the spirometer.~* The patient will be instructed to exhale letting all the breath out.~* patient will asked to close the lips around the mouthpiece of the spirometer.~* patient will be instructed to inhale slowly, breathing in until unable to do any more, this would raise the balls to the top of the column.~* patient will be asked to hold the breath as long as possible (at least five seconds) then exhale slowly.~* Session will be in the form of 30 times in sets, each set consist of 5-6 repetitions with rest 1 minute between sets.~* Intensity of exercise will be increased by increasing time of session, time of holding the breath and numbers of repetitions according to patient's status.
Study: NCT05351502

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitric Oxide 25,000 ppm
Description: Intratumoral injection of 25,000 gNO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitric Oxide 50,000 ppm
Description: Intratumoral injection of 50000 gNO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitric Oxide 100,000 ppm
Description: Intratumoral injection of 100,000 gNO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitric Oxide selected dose
Description: Intratumoral injection of selected does on gNO
Study: NCT05420168

Intervention type: OTHER
Intervention: Automatic tool to identify inappropriate antibiotic prescriptions
Description: The system will identify inappropriate antibiotic prescriptions.
Study: NCT05222750

Intervention type: OTHER
Intervention: Pre-COVID-19
Description: Pre-COVID-19

Intervention type: OTHER
Intervention: COVID-19
Description: COVID-19

Intervention type: OTHER
Intervention: COVID-19 vaccination roll-out
Description: COVID-19 vaccination roll-out
Study: NCT04966572

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Presurgical vacuum formed nasoalveolar molding aligners
Description: at first visit, the infants will receive this appliance which is a maxillary vacuum plate incorporated with palatal screw, the infant's parents will be instructed to activate the screw and apply horizontal tap which will be placed at the base of nose in order to approximate lip segments and to change tape daily. After that, The infants will be recalled one week after the first visit to add the nasal stents into the appliance.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional Grayson acrylic formed nasoalveolar molding appliances
Description: at first visit, the infants will receive this appliance which is a maxillary acrylic plate without adding taping, the infants will be recalled bi weekly for activating the appliance.~When the cleft alveolar gap is reduced to 6mm or less, a pair of nasal stents will be added to mold the nasal cartilage. the infants will be followed up for 4-6 months.
Study: NCT05871060

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Whey Protein Concentrate
Description: Whey protein concentrate consumed 30 minutes prior to breakfast and lunch meals

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Flavoured water consumed 30 minutes prior to breakfast and lunch meals
Study: NCT05825079

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight-Bearing Feedback
Description: Feedback on how much weight patients are exerting on their crutch/injured lower extremity (measured via Smart Crutch Tip) will be delivered to their mobile phones.
Study: NCT05871060

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whey hydrolysate
Description: Whey hydrolysate consumed 30 minutes prior to breakfast and lunch meals
Study: NCT05825079

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Smart Crutch Tip
Description: The device is attached to the crutch and measures how much weight-bearing load is exerted onto its axis. The device is capable of transmitting this data into the patient and physicians' user interface.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smart Crutch Tip
Description: The device is attached to the crutch and measures how much weight-bearing load is exerted onto its axis. The device is capable of transmitting this data into the patient and physicians' user interface.
Study: NCT05955469

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FS4 then TFS4 (cochlear implant)
Description: Cochlear implant with default fitting then with tonotopy-based fitting

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TFS4 then FS4 (cochlear implant)
Description: Cochlear implant with tonotopy-based fitting then with default fitting
Study: NCT01302509

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: industrialized oral supplementation (IOS) and tube feeding regimen (TFR) with Nutren
Description: The oral and tube supplement offered was Nutren Jr® (for patients aged 1 - 9 years) or Nutren 1.0- Nestlé Clinical Nutrition-Brazil (for those aged 10 years or over). This supplement was a whole powder formulation that presented a macro composition of 52% carbohydrates, 12% proteins and 36% lipids. Its vitamins were A, D, E, K, B complex, biotin and choline; its trace elements were iron, copper, zinc, manganese, selenium, chromium and molybdenum; its macroelements were potassium, calcium, sodium, chlorine, iodine, magnesium and phosphorus; and it contained taurine and L-carnitine presenting 1.0 kcal/ml.
Study: NCT05628441

Intervention type: OTHER
Intervention: Computer Aided Detection system for Barrett's neoplasia
Description: CADe system running in the back, not directly interfering with patient care
Study: NCT06204016

Intervention type: DRUG
Intervention: Estradiol Valerate
Description: To elevate estradiol levels each woman will receive 12mg on two consecutive days (total 24mg) of estradiol valerate (Progynova21©)

Intervention type: DRUG
Intervention: Estradiol Valerate
Description: To elevate estradiol levels each woman will receive 12mg on two consecutive days (total 24mg) of estradiol valerate (Progynova21©)

Intervention type: DRUG
Intervention: Placebo
Description: Placebo tablets will be administered as placebo-controlled condition (P-Tabletten White 7mm, Lichtenstein)

Intervention type: DRUG
Intervention: Placebo
Description: Placebo tablets will be administered as placebo-controlled condition (P-Tabletten White 7mm, Lichtenstein)
Study: NCT06609434

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation
Description: This study is the first to apply radiofrequency ablation to multiple recurrent intrahepatic lesions of colorectal cancer liver metastases.
Study: NCT06616402

Intervention type: DEVICE
Group type: OTHER
Intervention: prototype prosthetic group
Description: These 3 sessions will commence only upon successful completion of the prosthesis safety and reliability tests conducted in the preceding sessions.~For each module combination, a session will be conducted to assess motor performance through the acquisition of spatiotemporal parameters and energy efficiency parameters of gait. Motor performance will be evaluated using functional assessment tests and data will be recorded during the following activities:~* parallel bar walking on flat ground~* parallel bar walking on an inclined surface~* treadmill walking with a safety harness~* stair climbing/descending with a handrail~* standing up and sitting down from a chair within parallel bars At the end of each session, satisfaction questionnaires (ad hoc questionnaire) will be completed. At the end of the experiment, a usability scale for the devices (ad hoc System Usability Scale) will be completed.~Each session is expected to last approximately 2.5 hours.
Study: NCT06615778

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivated Social Emotional Learning
Description: MSEL arm consists of three intervention components: 1) CSEL, 2) the meaningful role tasks, and 3) the Secret Angel activity. First, participants in the MSEL arm will receive the same 6-session SEL as participants in the Curriculum-based Social-Emotional Learning arm.~Second, other than the CSEL, the second component is the Class Diploma tasks adopted from the pupil responsibilities intervention developed by Ellies et al. (2016). Participants will be provided with a list of meaningful roles and select the role they are willing to take based on their talents and interests. Each participant will take the role for two weeks, fulfilling the related duties and responsibilities. The third component is the Secret Angel, in which participants will anonymously recognize each other via the appraisal notes on Shout Out for Your Board.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Curriculum-based Social Emotional Learning
Description: In the CSEL arm, 6-session SEL training will be delivered as the experimental component. The primary goal of the SEL training is to reduce traditional bullying and cyberbullying perpetration and victimization by enhancing students' social-emotional competence, which has been examined to be the protective factor for bullying-related behaviors.~Each session lasts 40 minutes and is delivered by the headteacher in each class weekly as an after-school workshop. The SEL curriculum is tailored to the social-emotional needs of primary school students, as suggested by CASEL (2013). Also, building on past literature highlighting the lack of SEC as a risk factor linked to bullying behaviors both in the physical and cyber world, specific topics such as self-appreciation (self-awareness), stress management (self-management), respect and acceptance (social awareness), and conflict resolution (relationship skills) incorporated into the curriculum design.
Study: NCT06616883

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5221_01
Description: single dose administration (DA-5221_01 one tablet once a day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5221_01
Description: single dose administration (DA-5221_01 one tablet once a day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5221_01-R1 + DA-5221_01-R2
Description: single dose administration (DA-5221_01-R1 one tablet once a day + DA-5221_01-R2 one tablet once a day)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-5221_01-R1 + DA-5221_01-R2
Description: single dose administration (DA-5221_01-R1 one tablet once a day + DA-5221_01-R2 one tablet once a day)
Study: NCT06616090

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse Implemented Infant-Mother Attachment Security Program
Description: The intervention will draw on video-feedback of mother-infant interactions during the well-child visit. Nurses will videotape the dyad during routine visit in the Family Health Center and show short clips to mothers during the session in order to provide mother positive feedback on their sensitive caregiving. Additionaly, intervention mothers will be exposed to the reminders (e.g., pictures, posters, short film screenings) reflecting maternal sensitivity and secure attachment in the waiting rooms of the intervention Family Health Centers.
Study: NCT06617494

Intervention type: OTHER
Intervention: Pain modulation testing
Description: During the visit, noxious heat stimuli will be applied bilaterally to the face and distant body sites as part of conditioned pain modulation (CPM) testing. The test stimuli will be individually tailored to be moderately painful, while the conditioning stimulus will vary in intensity: moderately painful, non-painful, and sham heat. Participants will also record daily TMD pain intensity ratings for seven days before and after the visit.

Intervention type: OTHER
Intervention: Pain modulation testing
Description: During the visit, noxious heat stimuli will be applied bilaterally to the face and distant body sites as part of conditioned pain modulation (CPM) testing. The test stimuli will be individually tailored to be moderately painful, while the conditioning stimulus will vary in intensity: moderately painful, non-painful, and sham heat. Participants will also record daily TMD pain intensity ratings for seven days before and after the visit.
Study: NCT06674694

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole long-acting injection
Description: A single injection was administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole long-acting injection
Description: A single injection was administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole long-acting injection
Description: A single injection was administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole long-acting injection
Description: A single injection was administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole long-acting injection
Description: A single injection was administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brexpiprazole long-acting injection
Description: A single injection was administered.
Study: NCT06678555

Intervention type: DRUG
Intervention: Lorlatinib
Description: Lorlatinib is an ALK/ROS1 tyrosin kinase inhibitor.
Study: NCT06678737

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CBIT +cTBS
Description: 10 daily sessions of CBIT plus cTBS, with MRI, behavioral, and clinical assessments before and after treatment and at 1-, 3-, and 6-month follow-ups.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: CBIT +sham cTBS
Description: 10 daily sessions of CBIT plus sham cTBS, with MRI, behavioral, and clinical assessments before and after treatment and at 1-, 3-, and 6-month follow-ups.
Study: NCT05187650

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ekso (EksoNR, Ekso Bionics)
Description: The EksoNR is a powered exoskeleton designed to be used in a rehabilitation setting. The device meets the provision of the Council Directive 93/42/EEC concerning medical devices and is used for gait training in neurorehabilitation.
Study: NCT05452993

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Analysed Retinophotography
Description: taking 2 retinophotographs per eye, and then analysed by AI software to detect Diabetic retinopathy
Study: NCT06175650

Intervention type: PROCEDURE
Intervention: Cardiac surgery
Description: Cardiac surgery of all types

Intervention type: PROCEDURE
Intervention: Cardiac surgery
Description: Cardiac surgery of all types
Study: NCT05187650

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ekso (EksoNR, Ekso Bionics)
Description: The EksoNR is a powered exoskeleton designed to be used in a rehabilitation setting. The device meets the provision of the Council Directive 93/42/EEC concerning medical devices and is used for gait training in neurorehabilitation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FES (RehaMove2, Hasomed)
Description: RehaMove 2 sends electrical impulses via electrodes to nerves to evoke muscle contraction. The device meets the provision of the Council Directive 93/42/EEC concerning medical devices.
Study: NCT06484881

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Daniel Alain Probiotic Treatment for Androgenetic Alopecia
Description: Probiotic

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical minoxidil 5%
Description: Topical minoxidil 5%
Study: NCT04826055

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: biliary limb as fixed length
Description: n all loop bypass procedures we will don't count the total length of small intestine and make the biliary limb as a fixed from total small intestine length as mentioned in literature

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: biliary limb as a percentage from small intestine length
Description: in all loop bypass procedures we count the total length of small intestine and make the biliary limb as a percentage from total small intestine length rather than fixed length
Study: NCT04727723

Intervention type: DRUG
Intervention: Lutathera®
Description: Treatment with Lutathera® will be independent from participation in this observational study and must not be initiated for the purpose of participating in this study. The decision to treat patients with Lutathera® will occur before patients are enrolled in the study.
Study: NCT05422716

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Epidural implant stimulation device
Description: Individuals randomized to the Baclofen pump device group will continue with their clinical surgical and maintenance plan while also participating in all of the outcomes (assessments). The epidural implant group will undergo the research protocol for epidural stimulator surgical implant followed by mapping studies to identify targeted stimulation configurations for spasticity.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Epidural implant stimulation device
Description: Individuals randomized to the Baclofen pump device group will continue with their clinical surgical and maintenance plan while also participating in all of the outcomes (assessments). The epidural implant group will undergo the research protocol for epidural stimulator surgical implant followed by mapping studies to identify targeted stimulation configurations for spasticity.
Study: NCT05385289

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A cognitive-behavioral approach of rumination as intervention for overgeneral mode of processing in perfectionism
Description: The B-experimental phase consists in a 6-session intervention targeting rumination and lasting for 3 weeks. The intervention was derived from 3 manuals: Rumination-Focused Cognitive-Behavioral Therapy for Depression (Watkins, 2016), Overcoming Perfectionism (Shafran et al., 2010), and Cognitive-Behavioral Treatment of Perfectionism (Egan et al., 2014). Participants will attend 2 sessions per week at home. Each week will end with an individual 30 minutes-debriefing session with an experimenter, to ascertain understanding of session content and homework.~Intervention sessions will be given in paper format to participant after the A-baseline-phase. A paper diary was also provided for homework, in addition to the session content caneva. Each session contains (a) theoretical content on ruminations linked to perfectionism, (b) exercises to create alternative habits to ruminations, and (c) homework to become aware of ruminations and to experiment with alternatives.
Study: NCT05515601

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirikizumab
Description: Administered SC.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirikizumab
Description: Administered SC.
Study: NCT06425237

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: music therapy
Description: standard patient care in interventional radiology associated with a well-being atmosphere with the implementation of music therapy (soothing sound environment) in the preparation box and in the examination room.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: music therapy
Description: standard patient care in interventional radiology associated with a well-being atmosphere with the implementation of music therapy (soothing sound environment) in the preparation box and in the examination room.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aromatherapy
Description: standard patient care in interventional radiology associated with a well being atmosphere with the implementation of aromatherapy (essential oil of Ylang Ylang) in the preparation box and in the examination room.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aromatherapy
Description: standard patient care in interventional radiology associated with a well being atmosphere with the implementation of aromatherapy (essential oil of Ylang Ylang) in the preparation box and in the examination room.
Study: NCT06435338

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient decision aid
Description: The patient decision aid for HPV vaccination among mid-adults, named HPV Decide. It is delivered online on a website.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Vaccine information sheet on HPV vaccination. Attention control condition.
Study: NCT05713292

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirfenidone Oral Product
Description: Pirfenidone 200mg tid for first week; subsequently, 400mg tid for 2 months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pirfenidone placebo
Description: Pirfenidone placebo
Study: NCT06434350

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enfortumab Vedotin
Description: Given by IV

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Given by Radiation Therapy
Study: NCT06549231

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: one course of IV rituximab consisting of an infusion of 1000 mg rituximab (diluted in 500 mL of saline 0.9 % sodium chloride) will be given at day 1, day 15 and an infusion of 500 mg rituximab (in 500 mL of saline 0.9 % sodium chloride) at week 24;

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: one course of intravenous placebo of rituximab consisting of an infusion of 500 mL of saline (0.9% sodium chloride) infusion will be given at day 1, day 15 and week 24;
Study: NCT04862312

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VideoDine
Description: Participants will VideoDine with a dining partner at least six times during an eight week period. VideoDining involves sharing a meal with someone not physically present using video chat technology. Dining partners will be recruited, trained and paired with participants. Participants will be provided Amazon Echo Show devices for video chat.