TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05987007

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Acoustic slow-wave activity enhancement
Description: The acoustic enhancement of slow-wave activity will be conducted using the Dreem2 headband. This device utilizes five dry-EEG electrodes (O1, O2, FpZ, F7, and F8), a 3D accelerometer, and a pulse oximeter to detect slow-wave activity and generates acoustic stimulation of slow-waves to augment slow-wave sleep.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive behavioral therapy for insomnia
Description: Cognitive behavioral therapy for insomnia (CBTI) is a well-established first-line or complimentary treatment for insomnia which consists of cognitive and behavioral modifications, including addressing maladaptive sleep-related behaviors, controlling sleep environment, and limiting time spent in bed.
Study: NCT06570798

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Blinatumomab
Description: SC Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Blinatumomab
Description: SC Injection
Study: NCT06575088

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard tourniquet pressure (250 mmHg)
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard tourniquet pressure (250 mmHg)
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Limb occlusion pressure
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Limb occlusion pressure
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cotton Pad
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cotton Pad
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elastic stockinette
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.
Study: NCT05593198

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Khoury technique
Description: the bone block will be used following the principles of the Khoury technique to augment the bone volume.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Guided bone regeneration
Description: the membrane and the bone granules will be used to perform the guided bone regeneration technique.
Study: NCT06066281

Intervention type: BEHAVIORAL
Intervention: Neuropsychological assessment
Description: All participants who will meet the inclusion criteria will be adminstered a pencil-paper neuropsychological tests battery including: the Digit Span Backward Task, the Brief Repeatable Battery of Neuropsychological Tests and the CST. After 15 days from the baseline evaluation the CST will be re-administrated to all subjects.
Study: NCT05889806

Intervention type: OTHER
Intervention: Observational Study Only. NO Intervention.
Description: Observational Study Only. NO Intervention.

Intervention type: OTHER
Intervention: Observational Study Only. NO Intervention.
Description: Observational Study Only. NO Intervention.
Study: NCT03166371

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Liposomal Glutathione (GSH)
Description: Two teaspoons (containing 840 mg GSH, 420 mg/tsp) liposomal GSH (ReadiSorb®) will be taken orally twice daily for a total daily dose of 1680 mg GSH/day. Liposomal GSH will be refrigerated until use and mixed in ≈ 250 mL water or juice for oral intake. The study product will be consumed daily for 90 consecutive days after hospital discharge.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Two teaspoons of placebo product will be taken orally twice daily. The placebo will be refrigerated until use and mixed in ≈ 250 mL water or juice for oral intake. The placebo will be consumed daily for 90 consecutive days after hospital discharge.
Study: NCT04983758

Intervention type: OTHER
Intervention: Oral Rehabilitation with dental implants
Description: Patients have been treated with oral dental implants supporting fixed dental prostheses

Intervention type: OTHER
Intervention: Oral Rehabilitation with dental implants
Description: Patients have been treated with oral dental implants supporting fixed dental prostheses

Intervention type: OTHER
Intervention: Oral Rehabilitation with dental implants
Description: Patients have been treated with oral dental implants supporting fixed dental prostheses
Study: NCT06003465

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: LY3437943
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3437943
Description: Administered SC

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test
Description: Used to administer LY3437943 SC

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Reference
Description: Used to administer LY3437943 SC
Study: NCT06575088

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elastic stockinette
Description: The effectiveness of the protective padding material placed on the skin with a pneumatic tourniquet cuff and the pneumatic tourniquet pressure determination methods were compared.
Study: NCT05193344

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A digital care solution for patients with Heart Failure
Description: A digital solution that provides remote symptom monitoring and support of lifestyle-changes by gamification, altruistic rewards, and engaging content with relevant tasks or missions to be completed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care for patients with Heart Failure
Description: The best medical therapy including start or optimization of secondary preventive pharmacotherapy, and advise on modifiable risk factors. The participants in the control arm will also receive an information leaflet about relevant lifestyle modifications for HF.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care for patients with Heart Failure
Description: The best medical therapy including start or optimization of secondary preventive pharmacotherapy, and advise on modifiable risk factors. The participants in the control arm will also receive an information leaflet about relevant lifestyle modifications for HF.
Study: NCT04797741

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IDEA3 Intervention
Description: Delivery of IDEA3 intervention, a 12-hour online sexual assault resistance intervention for college women.
Study: NCT06359236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BI'KILO Intervention
Description: The study consists of three stages: preparation phase, implementation phase and follow-up phase. During the preparation phase, participants' weight and body fat ratio will be calculated using a body analysis scale, and their height, waist and hip circumference will be measured.~The implementation phase will last six weeks and consists of six modules, each lasting one week. The skills and practices aimed to be acquired in each module will be required to be applied in the following practice modules.~At the end of the implementation phase, participants' weight, waist and hip circumferences will be measured again.~The final phase, called the follow-up phase, will last four weeks. During this phase, participants will continue to keep a self-monitoring record of their eating and physical exercise, complete a hunger scale, and application card notifications will continue to be displayed.
Study: NCT06163482

Intervention type: OTHER
Intervention: Mixed meal
Description: Each individual will ingest 5 mL/kg of Boost energy drink.

Intervention type: OTHER
Intervention: Mixed meal
Description: Each individual will ingest 5 mL/kg of Boost energy drink.

Intervention type: OTHER
Intervention: Mixed meal
Description: Each individual will ingest 5 mL/kg of Boost energy drink.

Intervention type: OTHER
Intervention: Mixed meal
Description: Each individual will ingest 5 mL/kg of Boost energy drink.
Study: NCT06142825

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Community-Facility Transfusion Committee (CFTC)
Description: Community-Facility Transfusion Committees (CFTCs) are intended to incorporate diverse representation involving hospital, community, and county leadership, to improve blood availability and transfusion at the point-of-care.
Study: NCT06403579

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: virtula reality goggles
Description: no intervention

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtula reality goggles
Description: no intervention
Study: NCT04951674

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High fiber diet
Description: 30 grams of fiber per day

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control diet
Description: No diet education and change in diet
Study: NCT05122078

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Remifentanil infusion rate is adjusted according to the conventional method of blood pressure and heart rate monitroing. Blood pressure and heart rate are controlled to be within 20% of baseline. Investigators will not monitor ANI in this group.
Study: NCT05565807

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: STI-6129
Description: Anti-CD38 A2 human antibody drug conjugate (ADC) containing an antibody covalently bound to a duostatin tubulin inhibitor.
Study: NCT06550297

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Medically Tailored Meals and Nutritional Counseling
Description: God's Love We Deliver's current MTM program, which consists of weekly home-delivered MTMs and nutritional counseling by a Registered Dietitian Nutritionist for an 8-month period. The Food is Medicine Coalition Clinical Committee establishes and regularly updates the MTM Nutrition Standards, which catalogue the nutrition quality of this evidence-based intervention. Arms 1-3 will receive 10 MTMs per week for 8 months. Arm 4 will receive a distinct dosing down approach as follows: 10 MTMs/week in months 1-3, 9 MTMs/week in month 4, 8 MTMs/week in month 5, 7 MTMs/week in month 6, 6 MTMs/week in month 7, and 5 MTMs/week in month 8.
Study: NCT05674396

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy
Description: Participants will receive radiation as per the schedule discussed with the study doctor.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Traditional Palliation
Description: Participants will receive radiation as per the schedule discussed with the study doctor.
Study: NCT05631184

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-administered acupressure group
Description: Self-administered acupressure treatment group was developed on the basis of previous systematic reviews and clinical studies of acupuncture and acupressure for depression. It has robust theoretical basis of TCM. The acupoints selected are commonly used for depression according to a recent systematic review and recommended by other clinical practice guidelines.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mental health education group
Description: Mental health education training group was developed based on the materials regarding depression and mental health from the Centre of Health Protection, Department of Health, the Government of Hong Kong SAR and reviewed by a clinical psychologist.
Study: NCT06274684

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of Virtual Reality Assistance during prostate biopsies
Description: Patient will be equipped with VR headset providing a immersive experience during prostate biopsies
Study: NCT04923555

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vegetable proteins (VP) rich in leucine, cystein, arginine
Description: 33 volunteers will consume 400 ml of yogurt with vegetable proteins (VP) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of vegetable proteins.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vegetable proteins (VP) rich in leucine, cystein, arginine
Description: 33 volunteers will consume 400 ml of yogurt with vegetable proteins (VP) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of vegetable proteins.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Vegetable proteins (VP) rich in leucine, cystein, arginine
Description: 33 volunteers will consume 400 ml of yogurt with vegetable proteins (VP) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of vegetable proteins.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal proteins (AP)
Description: 33 volunteers will consume 400 ml of yogurt with animal proteins (AP) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of animal proteins.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal proteins (AP)
Description: 33 volunteers will consume 400 ml of yogurt with animal proteins (AP) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of animal proteins.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Animal proteins (AP)
Description: 33 volunteers will consume 400 ml of yogurt with animal proteins (AP) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of animal proteins.
Study: NCT05229523

Intervention type: OTHER
Intervention: repeated assessments
Description: validity and reliability of the Modified Four Square Step Test (mFSST) in children with cerebral palsy with the tests of Pediatric Berg Balance Scale (PBSS), Timed Up and Go Test (TUG), Pediatric Functional Reaching Test (PFUT)
Study: NCT04231500

Intervention type: DIAGNOSTIC_TEST
Intervention: Skin swabs
Description: Pre-moistened skin swabs will be collected before the patient starts the conditioning regimens (before conditioning; start of HSCT = day 0, on the day of the transplantation an the repeated in week 4, 12, 24, 36 and 52 after allo-HSCT. The first swab serves as baseline reference (ideally taken at the earliest one week after a systemic antibiotic treatment). Swabs will be taken from the neck, back, right hip, buccal oral cavity and the genital mucosae. In patients who develop acute or chronic skin-GVHD additional swabs will be taken from affected skin at the time of diagnosis and then again according to the schedule of the non-lesioned skin swabs.

Intervention type: DIAGNOSTIC_TEST
Intervention: Skin swabs
Description: Pre-moistened skin swabs will be collected before the patient starts the conditioning regimens (before conditioning; start of HSCT = day 0, on the day of the transplantation an the repeated in week 4, 12, 24, 36 and 52 after allo-HSCT. The first swab serves as baseline reference (ideally taken at the earliest one week after a systemic antibiotic treatment). Swabs will be taken from the neck, back, right hip, buccal oral cavity and the genital mucosae. In patients who develop acute or chronic skin-GVHD additional swabs will be taken from affected skin at the time of diagnosis and then again according to the schedule of the non-lesioned skin swabs.
Study: NCT04923555

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: No protein (T)
Description: 33 volunteers will consume 400 ml of yogurt without any protein (T) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of animal proteins.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: No protein (T)
Description: 33 volunteers will consume 400 ml of yogurt without any protein (T) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of animal proteins.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: No protein (T)
Description: 33 volunteers will consume 400 ml of yogurt without any protein (T) rich in leucine, cystein and arginine only once during the visit. At the beginning and the end of the intervention, exploration will be conducted at fasted state and at post-prandial state after the administration of animal proteins.
Study: NCT04231500

Intervention type: DIAGNOSTIC_TEST
Intervention: Skin punch biopsies
Description: During the first visit, a single skin punch biopsy will be taken to state the skin condition and microbiome before allo-HSCT. Further biopsies will only be taken in case of acute or chronic cutaneous GVHD. A 4-6 mm punch biopsy will be taken from the affected skin area and a second one from a nearby unaffected part of the skin. Before the biopsy, skin disinfection will be performed to avoid contamination with surface bacteria.

Intervention type: DIAGNOSTIC_TEST
Intervention: Skin punch biopsies
Description: During the first visit, a single skin punch biopsy will be taken to state the skin condition and microbiome before allo-HSCT. Further biopsies will only be taken in case of acute or chronic cutaneous GVHD. A 4-6 mm punch biopsy will be taken from the affected skin area and a second one from a nearby unaffected part of the skin. Before the biopsy, skin disinfection will be performed to avoid contamination with surface bacteria.

Intervention type: DIAGNOSTIC_TEST
Intervention: additional blood sampling
Description: an additional tube of blood (2.7ml) and an additional tube of serum (6ml) will be taken and frozen during visits 1, 2, 3 and 7 in the course of blood collection, in order to be able to carry out any later laboratory tests that may prove to be useful depending on the course of the study.

Intervention type: DIAGNOSTIC_TEST
Intervention: additional blood sampling
Description: an additional tube of blood (2.7ml) and an additional tube of serum (6ml) will be taken and frozen during visits 1, 2, 3 and 7 in the course of blood collection, in order to be able to carry out any later laboratory tests that may prove to be useful depending on the course of the study.
Study: NCT04802343

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY1817080
Description: Oral, tablet.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral, tablet.
Study: NCT06234631

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epidiolex oral solution
Description: Participants assigned to CBD will take the medication one hour before or two hours after eating a meal.~If participants can't tolerate the full-strength dose, the participant can decrease the dosing to 0.75 milliliter twice a day. If this is still not well tolerated, dosing can further be decreased to 0.75 milliliter once per day in the evening.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epidiolex oral solution
Description: Participants assigned to CBD will take the medication one hour before or two hours after eating a meal.~If participants can't tolerate the full-strength dose, the participant can decrease the dosing to 0.75 milliliter twice a day. If this is still not well tolerated, dosing can further be decreased to 0.75 milliliter once per day in the evening.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epidiolex oral solution
Description: Participants assigned to CBD will take the medication one hour before or two hours after eating a meal.~If participants can't tolerate the full-strength dose, the participant can decrease the dosing to 0.75 milliliter twice a day. If this is still not well tolerated, dosing can further be decreased to 0.75 milliliter once per day in the evening.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be instructed to take one hour before or two hours after eating a meal.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will be instructed to take one hour before or two hours after eating a meal.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will be instructed to take one hour before or two hours after eating a meal.
Study: NCT05195255

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Prebiotic
Description: Guar gum (8 g/d) will be administered for 18 days
Study: NCT05115188

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dex4/ dextrose
Description: Participants will be asked to ingest 21 Dex4® tablets and no more than 300ml of water within 5 minutes. Blood draws will be performed at fasting (before ingesting the dextrose monohydrate tablets), as well as 1 hour after (+/- 15 minutes) and 2 hours (+/- 15 minutes) after ingesting the dextrose monohydrate tablets.

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Glucose beverage
Description: For the 2 hour oral glucose tolerance test (OGTT), women fast for 8 hours and then consume 75g of glucose beverage, and serum glucose levels are taken at fasting, 1 and 2 hours after drinking the glucose beverage. The 75g OGTT is the gold standard and is performed for GDM diagnosis.
Study: NCT05760807

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin nasal spray
Description: Intranasal oxytocin, administered dose 24 international units (IU) twice daily, delivered over 7 days of a residential inpatient withdrawal admission.