TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06288347

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: GGON mobile app.
Description: The intervention will be done through an app named GGON, which is used to work on the dysfunctional beliefs that are associated with orthorexia nervosa. The app is made up of a series of levels comprising the topics based in cognitive-conductual perspective that are related to Orthorexia Nervosa. At each level, affirmations in the form of beliefs appear on the screen, and the person must accept them if they are functional, adaptive and positive; or reject them if they are dysfunctional, maladaptive and negative.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GGON mobile app.
Description: The intervention will be done through an app named GGON, which is used to work on the dysfunctional beliefs that are associated with orthorexia nervosa. The app is made up of a series of levels comprising the topics based in cognitive-conductual perspective that are related to Orthorexia Nervosa. At each level, affirmations in the form of beliefs appear on the screen, and the person must accept them if they are functional, adaptive and positive; or reject them if they are dysfunctional, maladaptive and negative.
Study: NCT05936255

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Give to Others Module
Description: Negative interpersonal beliefs are targeted via cognitive-behavioral strategies, including evaluation of cognitive distortions, and activity planning and tracking.
Study: NCT06147011

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D printed educational model
Description: Slide-based presention plus 3D printed thyroid fine needle aspiration model
Study: NCT04719416

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Guided Meditation
Description: Approximately 10 minute recording of guided meditation focuses on muscle relaxation.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Guided Meditation
Description: Approximately 10 minute recording of guided meditation focuses on muscle relaxation.
Study: NCT06566222

Intervention type: PROCEDURE
Intervention: chemoradiotherapy after surgery
Description: chemoradiotherapy after surgery vs preoperative chemoradiotherapy

Intervention type: OTHER
Intervention: High-risk Factors
Description: High-risk Factors vs low-risk Factors
Study: NCT05927233

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: 30 ml Methylprednisolone (30mg/kg) with a maximum dose of 500 mg
Study: NCT04916340

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Muscular Strength Training Group
Description: Week 1 3 days/week Bench Press - 1 set at 80% of one repetition maximum~(1RM) Bent Over Row - 1 set at 80% 1RM Back Squat - 1 set at 80% 1RM Romanian Deadlift - 1 set at 80% 1RM~Week 2 3 days/week Bench Press - 2 sets at 80% 1RM Bent Over Row - 2 sets at 80% 1RM Back Squat - 2 sets at 80% 1RM Romanian Deadlift - 2 sets at 80% 1RM~Weeks 3-10 3 days/week Bench Press - 3 sets at 80% 1RM Bent Over Row - 3 sets at 80% 1RM Back Squat - 3 sets at 80% 1RM Romanian Deadlift - 3 sets at 80% 1RM
Study: NCT05927233

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: 30 ml Normal saline
Study: NCT04916340

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Muscular Fitness Training Group
Description: Week 1 3 days/week Bench Press - 1 set at 65% 1RM Bent Over Row - 1 set at 65% 1RM Back Squat - 1 set at 65% 1RM Romanian Deadlift - 1 set at 65% 1RM~Week 2 3 days/week Bench Press - 2 sets at 65% 1RM Bent Over Row - 2 sets at 65% 1RM Back Squat - 2 sets at 65% 1RM Romanian Deadlift - 2 sets at 65% 1RM~Weeks 3-10 3 days/week Bench Press - 3 sets at 65% 1RM Bent Over Row - 3 sets at 65% 1RM Back Squat - 3 sets at 65% 1RM Romanian Deadlift - 3 sets at 65% 1RM
Study: NCT06059963

Intervention type: DEVICE
Intervention: Signal-C™
Description: Signal-C™ is a qualitative next generation sequencing-based in vitro diagnostic assay that uses targeted hybridization-based capture next-generation sequencing together with bioinformatics and machine learning algorithm for detection and combination of methylation and fragmentation associated DNA marker regions. Signal-C™ utilizes circulating cell-free DNA (cfDNA) isolated from plasma of peripheral whole blood collected via venipuncture in Streck Cell-Free DNA Blood Collection Tubes (BCTs).
Study: NCT05681429

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lignocaine, Dexmedetomidine, Sevoflurane, Paracetamol, Parecoxib
Description: To compare the recovery outcome of patients who undergo supratentorial craniotomy with opioid-based anaesthesia and opioid-free anaesthesia

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lignocaine, Dexmedetomidine, Sevoflurane, Paracetamol, Parecoxib
Description: To compare the recovery outcome of patients who undergo supratentorial craniotomy with opioid-based anaesthesia and opioid-free anaesthesia
Study: NCT06387329

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nitrofurantoin 100 MG
Description: No additional information

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitrofurantoin 100 MG
Description: No additional information
Study: NCT05491603

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DBI-001
Description: Topically administered

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DBI-002
Description: Topically administered

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Aqueous Gel
Description: Topically administered
Study: NCT06566222

Intervention type: OTHER
Intervention: High-risk Factors
Description: High-risk Factors vs low-risk Factors
Study: NCT06520735

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical nerve stimulation
Description: The pregnant women with emesis gravidarum will be treated by transcutaneous electrical nerve stimulation (TENS) on p6 acupuncture point for 30 minutes daily for 5 consecutive days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Capsicum plaster
Description: The pregnant women with emesis gravidarum will be treated with capsicum plaster on p6 acupuncture point for 12 hours per day for 5 consecutive days.
Study: NCT06308107

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Diazoxide
Description: 500 micromoles added to one liter of cardioplegia
Study: NCT06124534

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neurostimulation of the Occipital Nerve Field
Description: BliStim Neurostimulation system
Study: NCT05471518

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT06047964

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DCB
Description: Intracranial paclitaxel drug-eluting balloon catheters (SeQuent® Please CIS)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DCB
Description: Intracranial paclitaxel drug-eluting balloon catheters (SeQuent® Please CIS)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: POBA
Description: Intracranial PTA balloon catheter
Study: NCT05794386

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: LVA-guided LA substrate modification
Description: The LVA-guided additional LA ablation is included linear ablation or LVA zone border modification/isolation/ homogenization. The additional ablation strategies are finally selected at the physicians' discretion, considering LVA location and distribution.
Study: NCT04587856

Intervention type: OTHER
Group type: OTHER
Intervention: bone marrow withdrawal
Description: bone marrow samples evaluation
Study: NCT06493110

Intervention type: PROCEDURE
Intervention: Gastric ultrasound
Description: To compare gastric volumes in standard fasting state before surgery in diabetic and non-diabetic pregnant women by evaluating the gastric antrum with ultrasound.

Intervention type: PROCEDURE
Intervention: Gastric ultrasound
Description: To compare gastric volumes in standard fasting state before surgery in diabetic and non-diabetic pregnant women by evaluating the gastric antrum with ultrasound.
Study: NCT04937452

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rotigotine 4Mg/24Hrs Patch
Description: Rotigotine 4 mg/24Hrs administration for 24 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rotigotine 6Mg/24Hrs Patch
Description: Rotigotine 6 mg/24Hrs administration for 24 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administration for 24 weeks
Study: NCT06341270

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation
Description: transcutaneous electrical acupoint stimulation Transcutaneous electrical acupoint stimulation (TEAS) is a contemporary modification of traditional acupuncture that sends electrical impulses into acupoints through electrodes on the skin surface. In the TEAS group, patients will receive TEAS 30min before anesthesia until be discharged from the postanaesthesia care unit (PACU). The same treatment will be performed on the 1st, 2nd and 3rd days after surgery.The stimulation intensity will be adjusted in accordance with the maximal level tolerated by each patient.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham transcutaneous electrical acupoint stimulation
Description: Patients in the sham group will receive electrode attachment but without stimulation.
Study: NCT05847309

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Delayed extubation
Description: Patients randomized to delayed extubation, will be extubated 6-12 hours after endovascular treatment under general anesthesia.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Early extubation
Description: Patients randomized to early extubation, will be extubated \< 6 hours after endovascular treatment under general anesthesia.
Study: NCT05644899

Intervention type: PROCEDURE
Intervention: Interlaminar ultrasound-assisted intrathecal administration of nusinersen
Description: All procedures were performed with patients either seated or placed in a lateral decubitus. After skin disinfection with 2% chlorhexidine in 70% alcohol, using a convex array, the L3-4 or L4-5 intervertebral space was identified and a left paramedian sagittal oblique view was obtained; the probe was rotated 90° into a transverse orientation, centered on the neuraxial midline, and moved in either the cephalad or caudal direction to obtain a transverse interlaminar view; the intersection between the two markings of the spinal midline and interspinous space was identified as the spinal entry point of the needle. After local anesthesia (LA) with lidocaine 2%, a 25-gauge non-traumatic 90 mm Whitacre spinal needle or a traumatic 90 mm Quincke spinal needle was used to access the subarachnoid space. After confirmation of cerebrospinal fluid (CSF) flow, 5 mL of CSF were removed. Subsequently, nusinersen was administered intrathecally over 1-3 min.

Intervention type: PROCEDURE
Intervention: Landmark-based intrathecal administration of nusinersen
Description: All procedures were performed with patients placed in their most comfortable position (either seated or placed in a lateral decubitus). After skin disinfection with 2% chlorhexidine in 70% alcohol, conventional palpation of the superior aspect of iliac crest was performed and the palpated intercristal line was assumed to cross the spine at L4 vertebral body or L4-L5 interspace. The skin was marked with horizontal and vertical lines at the L3-L4 or L2-L3 interspaces and was referred as entry point of the needle. The procedure was then completed in the same fashion as for US-assisted technique.
Study: NCT06554678

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transnasal humidified rapid insufflation ventilatory exchange（THRIVE）
Description: Transnasal humidified rapid insufflation ventilatory exchange（THRIVE）

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional oxygen mask
Description: conventional oxygen mask
Study: NCT06315530

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Telitacicept
Description: 160mg once a week for 48 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SOC
Description: SOC treatment includes aspirin and/or vitamin K antagonists (VKA) and/or low molecular weight heparin.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOC
Description: SOC treatment includes aspirin and/or vitamin K antagonists (VKA) and/or low molecular weight heparin.
Study: NCT06145399

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-FDG PET/CT
Description: Standard-of-care 18F-FDG PET/CT will be performed using one of the commercially available GE PET/CT scanners

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone PET Imaging
Description: 18F- FDHT PET/MRI examinations will be performed to evaluate the association between 18F-FDHT uptake and AR expression levels as determined by immunohistochemistry (IHC) in selected lesions.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-FDHT
Description: 18F- FDHT PET/MRI examinations will be performed to evaluate the association between 18F-FDHT uptake and AR expression levels as determined by immunohistochemistry (IHC) in selected lesions.
Study: NCT05477368

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: D-β-hydroxybutyric acid with R-1,3-butanediol
Description: Pre-intervention (baseline) and post-intervention measurements will be obtained before and after the 90-day period respectively.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Inert placebo
Description: Pre-intervention (baseline) and post-intervention measurements will be obtained before and after the 90-day period respectively.
Study: NCT06566248

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQA3810 tablets+NUC
Description: TQA3810 is a novel, effective and highly selective small-molecule oral Toll-like receptors-8 agonist.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo+NUC
Description: NUC:~Entecavir Dispersible Tablets, Inhibit viral replication; Tenofovir Disoproxil Fumarate Tablets, Nucleotide reverse transcriptase inhibitors; Tenofovir Alafenamide Fumarate Tablets, Inhibit HBV replication.
Study: NCT06644729

Intervention type: PROCEDURE
Intervention: Arthroscopic Rotator Cuff Repair
Description: Arthroscopic Rotator Cuff Repair
Study: NCT05972954

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OMT-28
Description: once daily
Study: NCT06369077

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dorzolamide/timolol
Description: Compare half-frequency dosing of latanoprost and dorzolamide/timolol to full dosing. Compare also to timolol/brimonidine/dorzolamide/bimatoprost

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dorzolamide/timolol
Description: Compare half-frequency dosing of latanoprost and dorzolamide/timolol to full dosing. Compare also to timolol/brimonidine/dorzolamide/bimatoprost
Study: NCT06108297

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lithium
Description: Elemental lithium as lithium aspartate.
Study: NCT06063954

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: Electroacupuncture (EA) is a form of acupuncture in which a weak electric current is passed through the acupuncture needles into acupoints in the skin.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: Electroacupuncture (EA) is a form of acupuncture in which a weak electric current is passed through the acupuncture needles into acupoints in the skin.
Study: NCT05529641

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diaphragmatic resistance training
Description: 6 weeks home exercise of diaphragmatic resistance training will be emphasized.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cervical stabilization exercise
Description: Participants will finish 6 weeks supervised cervical stabilization exercise in person by physical therapist. Dissociated movement and movement control will be emphasized during cervical stabilization exercise.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cervical stabilization exercise
Description: Participants will finish 6 weeks supervised cervical stabilization exercise in person by physical therapist. Dissociated movement and movement control will be emphasized during cervical stabilization exercise.
Study: NCT04918680

Intervention type: DEVICE
Intervention: EcoFit® Total Hip System with implacross® E Polyethylene
Description: The EcoFit® Total Hip System is a primary hip replacement system indicated for patients who are candidates for a primary cementless hip replacement. implacross® E Polyethylene is one of the components in the EcoFit® system.
Study: NCT06026449

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gluten-free diet
Description: After initial fase of habitual diet (6 months), patients will start Gluten-free diet for a period of 12 months

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gluten-free diet
Description: After initial fase of habitual diet (6 months), patients will start Gluten-free diet for a period of 12 months
Study: NCT05970848

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Washing Pipe With a Spray Nozzle
Description: Administration of topical airway anesthesia via a washing pipe with a spray nozzle using the spray-as-you-go technique
Study: NCT06647446

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise supported by the digital physiotherapy and telerehabilitation software TRAK
Description: 8 week home therapeutic exercise program that includes flexibility and strength exercises scheduled through the software of digital physiotherapy and telerehabilitation TRAK. The program will be carried out with a frequency of 3 weekly sessions, preferably on alternate days. The program will be carried out with the support of the TRAK software (https://www.trakphysio.com/es/), which allows the exercises to be carried out in front of a camera that, with the help of an artificial intelligence system, offers feedback to the participant and allows you to keep a record of the sessions. As an addition to the home sessions, two face-to-face sessions will be held in the first and fifth weeks, respectively. The exercise program includes three levels of difficulty (easy, intermediate and difficult), with patients advancing to subsequent levels once each level is successfully overcome.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard home-based exercise
Description: 8 week home therapeutic exercise program that includes flexibility and strength exercises scheduled through a dossier and an exercise diary. The program will be carried out with a frequency of 3 weekly sessions, preferably on alternate days. The program will be carried out with the support of an information dossier of the exercises to be performed and a monitoring diary in which everything related to the sessions carried out will be noted.. As an addition to the home sessions, two face-to-face sessions will be held in the first and fifth weeks, respectively. The exercise program includes three levels of difficulty (easy, intermediate and difficult), with patients advancing to subsequent levels once each level is successfully overcome.
Study: NCT06450522

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacist co-management of HF medication optimization
Description: In addition to usual care, participants with an initial Post-Discharge Medicine Clinic visit randomized to the intervention arm will receive pharmacist co-management of their medications, with the intent of to achieve rapid, maximum-tolerated pharmacotherapy for HFrEF as outlined by the 2021 CCS HF guidelines, and for HFmrEF/HFpEF as outlined by the 2022 ACC/AHA HF guidelines. This intervention will be delivered by a staff pharmacist at the St. Paul's Hospital, using the standard procedures outlined below:~For HFrEF: Where possible, a patient will be prescribed the combination of an ARNI, evidence-based beta-blocker, MRA, and SGLT2i at target HFrEF doses, along with personalized therapies as outlined in the 2021 CCS HF guidelines.~For HFmrEF: We will target ACEI/ARB/ARNI+BB+MRA+SGLT2i. For HFpEF: We will target SGLT2i+MRA +/- ACEI/ARB/ARNI. The intervention will incorporate key components identified in a systematic review of observational studies of pharmacist-led optimization of HF.

Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: Usual care
Study: NCT06647693

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motor Synchrony Games (MSG)
Description: The motor synchrony games (MSG) intervention uses fun but progressively more challenging gross motor and imitation games to promote behavioral self-regulation. Primary activities include: songs and fingerplays, stop and go games, and imitation games. These games get progressively more challenging over time by varying signal/modality. For example, going from a verbal and gestural paired stop and go signal to only a gestural stop signal. A fidelity checklist is used to ensure the intervention is appropriately used with the following criteria (uses \>10 imitation trials, \>10 Stop \& Go games, \>3 trials/min on average with \>5 trials/min preferred, use of progressive challenge, opportunities for Child Choice, environmental arrangement, and therapeutic strategies such as modeling).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motor Synchrony Games (MSG)
Description: The motor synchrony games (MSG) intervention uses fun but progressively more challenging gross motor and imitation games to promote behavioral self-regulation. Primary activities include: songs and fingerplays, stop and go games, and imitation games. These games get progressively more challenging over time by varying signal/modality. For example, going from a verbal and gestural paired stop and go signal to only a gestural stop signal. A fidelity checklist is used to ensure the intervention is appropriately used with the following criteria (uses \>10 imitation trials, \>10 Stop \& Go games, \>3 trials/min on average with \>5 trials/min preferred, use of progressive challenge, opportunities for Child Choice, environmental arrangement, and therapeutic strategies such as modeling).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motor Synchrony Games (MSG)
Description: The motor synchrony games (MSG) intervention uses fun but progressively more challenging gross motor and imitation games to promote behavioral self-regulation. Primary activities include: songs and fingerplays, stop and go games, and imitation games. These games get progressively more challenging over time by varying signal/modality. For example, going from a verbal and gestural paired stop and go signal to only a gestural stop signal. A fidelity checklist is used to ensure the intervention is appropriately used with the following criteria (uses \>10 imitation trials, \>10 Stop \& Go games, \>3 trials/min on average with \>5 trials/min preferred, use of progressive challenge, opportunities for Child Choice, environmental arrangement, and therapeutic strategies such as modeling).