TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05715138

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: GPi-DBS
Description: An elaborate target/trajectory planning and a precise image fusion of MRI and stereotactic CT scanning are performed before surgery. After microelectrode recording, two sets of quadripolar DBS leads (contact interval is 1.5mm) will be inserted into the posteroventral part of bilateral GPi nuclei separately. Subsequently, an implantable pulse generator will be connected via extension wires and implanted at the left/right subclavicular area subcutaneously.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: STN-DBS
Description: An elaborate target/trajectory planning and a precise image fusion of MRI and stereotactic CT scanning are performed before surgery. After microelectrode recording, two sets of quadripolar DBS leads (contact interval is 0.5mm) will be inserted into the dorsolateral part of bilateral STN nuclei separately. Subsequently, an implantable pulse generator will be connected via extension wires and implanted at the left/right subclavicular area subcutaneously.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GPi-DBS devices
Description: 1. DBS electrode: 3387 (Medtronic, Minneapolis, MN, USA) or L302 (PINS Medical, Beijing, China) or 1210(SceneRay, Suzhou, China);~2. Extension wire: 37086 (Medtronic, Minneapolis, MN, USA) or E202 (PINS Medical, Beijing, China) or 1340/SR1341 (SceneRay, Suzhou, China);~3. Implantable pulse generator: ACTIVA PC/RC (Medtronic, Minneapolis, MN, USA) or G102/G102R (PINS Medical, Beijing, China) or 1180/SR1101 (SceneRay, Suzhou, China).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: STN-DBS devices
Description: 1. DBS electrode: 3389 (Medtronic, Minneapolis, MN, USA) or L301 (PINS Medical, Beijing, China) or 1200 (SceneRay, Suzhou, China);~2. Extension wire: 37086 (Medtronic, Minneapolis, MN, USA) or E202 (PINS Medical, Beijing, China) or 1340/SR1341 (SceneRay, Suzhou, China);~3. Implantable pulse generator: ACTIVA PC/RC (Medtronic, Minneapolis, MN, USA) or G102/G102R (PINS Medical, Beijing, China) or 1180/SR1101 (SceneRay, Suzhou, China).
Study: NCT04871828

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leukotriene Receptor Antagonist
Description: Zafirlukast

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05355935

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral tablet.
Study: NCT05737823

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Carers-ID online support programme
Description: The Carers-ID online programme, which consists of ten modules which cover topics including: promoting resilience, reducing anxiety, managing stress, accessing local supports, managing family conflict and information for siblings who are carers.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Carers-ID online support programme - Wait-list control
Description: The same programme as above delivered to the wait-list control after the T2 follow-up data has been collected.
Study: NCT05238272

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial random noise stimulation (tRNS)
Description: There will be 20 minutes of stimulation (real tRNS or sham tRNS), 40 minutes of MT (unilateral or bilateral) and 30 minutes of functional task training.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial random noise stimulation (tRNS)
Description: There will be 20 minutes of stimulation (real tRNS or sham tRNS), 40 minutes of MT (unilateral or bilateral) and 30 minutes of functional task training.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tRNS
Description: the electrode placement will be the same as the real stimulation conditions. The current will first turn up for 30 seconds and subsequently turn off in the next 30 seconds

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tRNS
Description: the electrode placement will be the same as the real stimulation conditions. The current will first turn up for 30 seconds and subsequently turn off in the next 30 seconds

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: the unilateral MT
Description: For the unilateral MT, the participants will practice movements using only the unaffected arm while the affected arm will remain relaxed behind the mirror during MT training. The training therapists will instruct the participants to look at the mirror reflection of the unaffected arm and imagine that it is the affected arm performing the task.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: the unilateral MT
Description: For the unilateral MT, the participants will practice movements using only the unaffected arm while the affected arm will remain relaxed behind the mirror during MT training. The training therapists will instruct the participants to look at the mirror reflection of the unaffected arm and imagine that it is the affected arm performing the task.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: the bilateral MT
Description: For the bilateral MT, the participants will be encouraged to move the affected arm as symmetrically and simultaneously as the unaffected hand during MT training. At the same time, participants will also be instructed to look at the mirror reflection of the unaffected arm and imagine that it is the affected arm performing the task. The activities practiced during MT will include intransitive movements (e.g., flexion and extension of the wrist) and transitive movements (e.g., picking up a pen).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: the bilateral MT
Description: For the bilateral MT, the participants will be encouraged to move the affected arm as symmetrically and simultaneously as the unaffected hand during MT training. At the same time, participants will also be instructed to look at the mirror reflection of the unaffected arm and imagine that it is the affected arm performing the task. The activities practiced during MT will include intransitive movements (e.g., flexion and extension of the wrist) and transitive movements (e.g., picking up a pen).
Study: NCT05523557

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Urban Training
Description: 1) one-to-one motivational interview for a maximum of 1h; 2) exercise following a dossier containing various maps of Urban Training walking trails, previously used in patients with COPD with a recommendation of doing a minimum of 1 circuit/day; or in case of living faraway from Urban Training walking trails, the instructions will be to walk at least 30 minutes per day ⩾5 days per week, at a pace reaching a dyspnoea Borg scale score of 4 -6; 3) a FitBit Inspire (FitBit, San Francisco, United States) to obtain direct feedback on the step count and intensity of PA; and 4) a motivational follow-up visit, in group, once per month during the follow-up period.
Study: NCT05355935

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral tablet.
Study: NCT06066840

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Basiliximab
Description: Basiliximab is a second-line treatment for steroid-resistant acute graft-versus-host disease.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vedolizumab
Description: Vedolizumab is a second-line treatment for steroid-resistant acute graft-versus-host disease.
Study: NCT06178094

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video Training
Description: The participants in the Training Group is to sent a total of eight episodes of the Diabetes Training Videos prepare by the researcher, twice a week, through smartphones after the first interview
Study: NCT04661267

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Stem Cell Support Formula
Description: This liquid supplement contains the following ingredients: chondroitin sulfate, glucosamine sulfate, vitamin C (ascorbic acid), curcumin and Bioperine®, resveratrol, L-carnosine, bitter melon, and vitamin D.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo comparator will look and taste similar without the active ingredients of the Stem Cell Support Formula.
Study: NCT05895695

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: levator muscle resection
Description: resection of levator muscle in congenital unilateral ptosis

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: levator muscle plication
Description: plication of levator muscle in congenital unilateral ptosis
Study: NCT06125574

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Medicine
Description: Individuals in the experimental cohort will undergo a systematic osteopathic manipulative treatment protocol encompassing paraspinal inhibition, rib raising, and condylar decompression techniques.
Study: NCT05117983

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: Real-time MRI-guided neuronavigation with a Visor neuronavigation system (ANT Neuro, Enschede, Netherlands) will be used for coil positioning. Left dorsolateral prefrontal cortex target is located in each participant.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: Real-time MRI-guided neuronavigation with a Visor neuronavigation system (ANT Neuro, Enschede, Netherlands) will be used for coil positioning. Left dorsolateral prefrontal cortex target is located in each participant.
Study: NCT05673330

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal Mobilizations
Description: 1. Headache SNAG: A posteroanterior mobilization of the second cervical vertebrae is sustained for 10 to 30 s with the aim to reduce headache intensity at the time of application. (6)~2. Maitland's C1-C7 PA Glide: A posteroanterior (PA) mobilization of the first till seventh cervical vertebra is achieved by applying a force on to a vertebral segment in a posteroanterior direction (Back to front).~The patients will receive Spinal Mobilizations consisting of 1 set of 6 repetitions once daily thrice per week for four weeks. Pre and post intervention values will be taken on 1st day and after 4 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial Release Technique
Description: Suboccipital Inhibition Technique: While the patient will be in the supine position, the physician sitting at the top end of the table will place the fingers of both hands on the patient's suboccipital region. Flexi-perpendicular long fingers exerting an inhibitory pressure on the muscle insertions of the neck extensors in the occiput, perpendicularly to muscle fibers, while the thumbs counterbalance the head against rotation. A deep and progressive pressure would be applied perpendicular to the fibers until a decrease in muscle tone would be detected. This deep and progressive pressure would be maintained for a total of 10 min until release of suboccipital tissues is achieved.~The patients will receive myofascial release with the frequency of 1 set and 10 repetitions once a day three times per week for four weeks. Pre and post intervention values will be taken on 1st day and after 4 weeks.
Study: NCT06490237

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: near field recording of human auditory nerve activity during retro sigmoid approach with contact electrode
Description: During surgery using a retro-sigmoid approach in the cerebellopontine angle (microvascular decompression, vestibular neurotomy, meningioma or schwannoma removal), near-field recording of human auditory nerve activity using a contact electrode is performed on patients with normal or impaired hearing threshold.~Each patient is explored preoperatively by hearing tests in noise and in silence. During the operation, stimuli are delivered in silence and in noise, under the same conditions as during the preoperative auditory exploration.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: near field recording of human auditory nerve activity during retro sigmoid approach with contact electrode
Description: During surgery using a retro-sigmoid approach in the cerebellopontine angle (microvascular decompression, vestibular neurotomy, meningioma or schwannoma removal), near-field recording of human auditory nerve activity using a contact electrode is performed on patients with normal or impaired hearing threshold.~Each patient is explored preoperatively by hearing tests in noise and in silence. During the operation, stimuli are delivered in silence and in noise, under the same conditions as during the preoperative auditory exploration.
Study: NCT05341466

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acute Intermittent Hypoxia
Description: 5 consecutive days of 15, 1.5 min episodes at 9% O2 (AIH) alternating with 21% O2 at 1 min intervals

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: SHAM Acute Intermittent Hypoxia
Description: 5 consecutive days of 15, 1.5 min episodes at 21% O2 (SHAM AIH) alternating with 21% O2 at 1 min intervals
Study: NCT06169501

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: App-based Mindfulness Intervention
Description: Participants in the trial will engage in a 30-day app-based mindfulness program called Unwinding Anxiety that they can complete over a maximum of 60 days. During this time, they will practice short daily mindfulness lessons and respond to a set of brief questions regarding their anxiety levels. Ultimately, we want to assess whether this intervention helps these caregivers feel less stressed and anxious.
Study: NCT04793048

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: a noninvasive intraoral electrotherapy device
Description: a noninvasive intraoral electrotherapy device to treat periodontal disease at-home for 20 minutes a day

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: a sham device
Description: a sham device to be used at-home for 20 minutes a day
Study: NCT05569603

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chronobiology-guided lifestyle interventions
Description: 1) timed bright light exposure using blue-enriched white light glasses, 2) recommendations for meal timing, and 3) sleep hygiene education
Study: NCT06253819

Intervention type: OTHER
Intervention: survey and physical test
Description: 6 min. walking test respiratory function test 30 second sit-stand test respiratory muscle test tıme up and go corbin posture analysis Waist/Hip Circumference Ratio Glucose and Cholesterol values Lanss Neuropathic Pain Scale

Intervention type: OTHER
Intervention: survey and physical test
Description: 6 min. walking test respiratory function test 30 second sit-stand test respiratory muscle test tıme up and go corbin posture analysis Waist/Hip Circumference Ratio Glucose and Cholesterol values Lanss Neuropathic Pain Scale
Study: NCT06319937

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound
Description: Ultrasound
Study: NCT05472662

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo 152a
Description: Placebo pressurised metered-dose inhaler (pMDI) formulated with the 152a propellant

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 134a
Description: Placebo pressurised metered-dose inhaler (pMDI) formulated with the 134a propellant
Study: NCT06432049

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: restoration for endodontically treated molar
Description: prefabricated stainless steel crown or endocrown

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: restoration for endodontically treated molar
Description: prefabricated stainless steel crown or endocrown

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: restoration for endodontically treated molar
Description: prefabricated stainless steel crown or endocrown
Study: NCT04842773

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound measurement
Description: Ultrasound measurement of sarcopenia in an elderly population
Study: NCT06034912

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-Intensity Red Light Therapy
Description: myopia and amblyopia comprehensive treatment instrument red light feeding treatment
Study: NCT05275088

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prizvalve® system
Description: Transcatheter atrioventricular valve replacement
Study: NCT05297136

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pancreatic Stenting
Description: Pancreatic stent of appropriate size and length is inserted to the pancreatic duct before distal pancreatectomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: No Stent
Description: No preoperative stenting with distal pancreatectomy alone
Study: NCT05103241

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] GP681
Description: 40 mg suspension containing 100μCi of \[14C\]GP681
Study: NCT05080426

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Supportive Supervisor Training 2.0
Description: FSST 2.0 is a workplace intervention package designed to increase supervisors' family and leave supportive behaviors and leave supportive behaviors. The package includes Workplace Assessment tool, 2 45-60 minute online training modules (family-supportive supervisor training and supervisors' leave supportive behavior training), a webinar, behavior training, and individualized feedback reports.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Supportive Supervisor Training 2.0
Description: FSST 2.0 is a workplace intervention package designed to increase supervisors' family and leave supportive behaviors and leave supportive behaviors. The package includes Workplace Assessment tool, 2 45-60 minute online training modules (family-supportive supervisor training and supervisors' leave supportive behavior training), a webinar, behavior training, and individualized feedback reports.
Study: NCT03435718

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxfendazole
Description: oral suspension

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxfendazole
Description: oral suspension

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxfendazole
Description: oral suspension

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxfendazole
Description: oral suspension

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Albendazole
Description: tablet
Study: NCT06241508

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation
Description: A standard 600-pulse TBS \[16\] will be administrated using a MagPro X100 stimulator (MagVenture, Denmark) and a 65-mm figure-of-eight coil. The measurement of the motor hotspot and individual RMT will be in accordance with our established methodology \[3, 9\]. For patients with stroke, the intensity of real stimulation will be 55% or 70% RMT of the unaffected M1 \[17\], depending on their assigned condition. Sham stimulation will be delivered using the same coil with 20% RMT of the unaffected M1 \[4, 6\]. The priming and conditioning sessions will be delivered to the ipsilesional M1 sequentially. In line with previous works, the interval between them will be 10 minutes \[2, 3\]. For healthy adults, the stimulation will be applied exclusively to the non-dominant (right) M1.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation
Description: A standard 600-pulse TBS \[16\] will be administrated using a MagPro X100 stimulator (MagVenture, Denmark) and a 65-mm figure-of-eight coil. The measurement of the motor hotspot and individual RMT will be in accordance with our established methodology \[3, 9\]. For patients with stroke, the intensity of real stimulation will be 55% or 70% RMT of the unaffected M1 \[17\], depending on their assigned condition. Sham stimulation will be delivered using the same coil with 20% RMT of the unaffected M1 \[4, 6\]. The priming and conditioning sessions will be delivered to the ipsilesional M1 sequentially. In line with previous works, the interval between them will be 10 minutes \[2, 3\]. For healthy adults, the stimulation will be applied exclusively to the non-dominant (right) M1.
Study: NCT06262282

Intervention type: BIOLOGICAL
Intervention: mycobacteriophage
Description: mycobacteriophage phage that has been found effective in killing participants NTM infection
Study: NCT06241508

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial magnetic stimulation
Description: A standard 600-pulse TBS \[16\] will be administrated using a MagPro X100 stimulator (MagVenture, Denmark) and a 65-mm figure-of-eight coil. The measurement of the motor hotspot and individual RMT will be in accordance with our established methodology \[3, 9\]. For patients with stroke, the intensity of real stimulation will be 55% or 70% RMT of the unaffected M1 \[17\], depending on their assigned condition. Sham stimulation will be delivered using the same coil with 20% RMT of the unaffected M1 \[4, 6\]. The priming and conditioning sessions will be delivered to the ipsilesional M1 sequentially. In line with previous works, the interval between them will be 10 minutes \[2, 3\]. For healthy adults, the stimulation will be applied exclusively to the non-dominant (right) M1.
Study: NCT04376567

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: One stage approach
Description: Upper extremity brachial basilic arteriovenous fistula will be created either using one stage or two stage approach.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: One stage approach
Description: Upper extremity brachial basilic arteriovenous fistula will be created either using one stage or two stage approach.
Study: NCT05100784

Intervention type: BIOLOGICAL
Intervention: HSSA test
Description: Human Sperm Survival Assay testing performed on different batches of different types of IVF consumables. In practice, 3 consumables from the same batch will be tested with 3 different sperms to ensure the repeatability of the result / test.
Study: NCT05007587

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 8mg lenvatinib (weight\<60kg) or 12mg lenvatinib (weight\>60kg) QD

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: 8mg lenvatinib (weight\<60kg) or 12mg lenvatinib (weight\>60kg) QD
Study: NCT05253755

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: DBI-001
Description: Topical application of DBI-001 gel on skin affected with atopic dermatitis.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Aqueous gel
Description: Topical application of aqueous gel on skin affected with atopic dermatitis.
Study: NCT02523092

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acthar gel
Description: Acthar gel given IM or SQ as per package insert