TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06328296

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation treatment
Description: Both groups are given rehabilitation treatment. The main intervention measures included: 1) non-invasive ventilator treatment, generally at least once every night and typically not exceeding continuous daily usage.; 2) attention to feeding and sleeping positions, with a recommended sleeping position of lateral recumbent and the head of the bed raised by 20-30°; 3) swallowing function training, such as tongue muscle stretching training, assisted anterior jaw protrusion training, lemon ice stimulation to the soft palate, pharyngeal wall, etc., generally 5 days per week, twice per day, 5-20 minutes each time; 4) pulmonary ultrashort wave therapy, generally at least 2-3 times a week, and not more than once a day; 5) physical therapy, such as intensive training for gross motor functions including lifting the head, turning over, sitting, crawling, standing, etc., generally 3-5 days per week, 1-2 times per day, 5-20 min each time.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation treatment
Description: Both groups are given rehabilitation treatment. The main intervention measures included: 1) non-invasive ventilator treatment, generally at least once every night and typically not exceeding continuous daily usage.; 2) attention to feeding and sleeping positions, with a recommended sleeping position of lateral recumbent and the head of the bed raised by 20-30°; 3) swallowing function training, such as tongue muscle stretching training, assisted anterior jaw protrusion training, lemon ice stimulation to the soft palate, pharyngeal wall, etc., generally 5 days per week, twice per day, 5-20 minutes each time; 4) pulmonary ultrashort wave therapy, generally at least 2-3 times a week, and not more than once a day; 5) physical therapy, such as intensive training for gross motor functions including lifting the head, turning over, sitting, crawling, standing, etc., generally 3-5 days per week, 1-2 times per day, 5-20 min each time.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Myofascial Release Therapy
Description: Myofascial release, also known as fascial release or fascial manipulation, is a physical therapy used to treat muscle and fascial tissue tension or pain. It involves applying appropriate pressure and stretching to release tight fascia and soft tissues, improving blood circulation, alleviating pain, and promoting rehabilitation. Myofascial release therapy is commonly used to treat muscle spasms, chronic pain, skeletal and joint issues, among others.
Study: NCT05615727

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: 2 mcg/kg of undiluted dexmedetomidine \[= 0.02 ml/kg\] and oral placebo tablet
Study: NCT05715190

Intervention type: OTHER
Group type: OTHER
Intervention: Education
Description: Visiting the medical psoriasis outpatient clinic. Receiving a medical consultation, phototherapy and methotrexate treatment. Psoriasis plaque measurement, psoriasis care and questionnaires will be provided by the institute's nurses. After baseline data collection (T0) and random allocation to the intervention group, this usual care will be enhanced by a multidisciplinary nurse-led educational program
Study: NCT05204030

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HPV Twitter Education Program - Narrative
Description: This study will evaluate the efficacy of social media messages through Twitter, using a randomized controlled trial to determine what types of messages resonate with parents. The investigators will examine narrative messages (i.e., stories). The central hypothesis is that parents who read narrative-focused messages will be more likely to report narrative engagement, intention to vaccinate their child, and self-reported vaccination compared to parents who read non-narrative messages.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: HPV Twitter Education Program - Non-Narrative
Description: This study will evaluate the efficacy of social media messages through Twitter, using a randomized controlled trial to determine what types of messages resonate with parents. The investigators will examine non-narrative messages (i.e., scientific information - numbers and facts). The central hypothesis is that parents who read narrative-focused messages will be more likely to report narrative engagement, intention to vaccinate their child, and self-reported vaccination compared to parents who read non-narrative messages.
Study: NCT05655611

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: first rib mobilization
Description: To perform the first rib mobilization, the patient remained lying supine with the head in the examiner's right hand. Examiner then palpated the left first rib and passively side-bended the patient's head to the left to relieve any muscular tension on the first rib. Patient was then asked to take a deep breath in and out. During exhalation, the examiner applied pressure to depress the first rib, holding it in place at the end of the exhalation. Then, holding the first rib in place, the patient was asked to inhale and exhale deeply again. The examiner continued applying pressure to hold the first rib in a position of relative depression during inhalation, and further depressed the first rib as able during exhalation. This process was repeated three times in two sets, for a total of six first rib depression mobilizations.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: muscle energy technique
Description: Muscle energy technique for glenohumeral joint restricted abduction-The therapist stood in front of the patient, then placed one hand over the top of the subject's involved shoulder. The therapist cups the glenohumeral joint to palpate for motion and the subjects are directed to press the elbow towards their body. Muscle energy technique was applied for five repetitions per set, five sets per session, one session per day, three days a week for three weeks with each repetition maintained for the duration of 7-1 seconds.
Study: NCT05180903

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: X-tra base & GrandioSO reinforced by Ribbond
Description: The missing peripheral tooth structure will be built up via 2-mm wedge-shaped a universal hybrid resin composite, GrandioSO . Then the polyethylene fibers will be wetted with an unfilled resin first . After removing the excess resin, fibers will be covered with a very thin layer of flowable composite X-tra base . After that, fibers will be bonded immediately against the peripheral missing walls and cured for 20 seconds. Then a bulk-fill flowable resin composite lining X-tra base will be applied in approximately 4 mm thick in bulk increments as needed to fill the cavity 2 mm short of the occlusal cavosurface and each increment will be light cured for 20 s. The remaining occlusal part of the cavity will be restored with a universal hybrid resin composite, GrandioSO . The shade of the composite will be selected according to the teeth to be restored. All cavities will be restored with open-sandwich technique (Deliperi, et al. 2017).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: X-tra base & GrandioSO reinforced by Ribbond
Description: The missing peripheral tooth structure will be built up via 2-mm wedge-shaped a universal hybrid resin composite, GrandioSO . Then the polyethylene fibers will be wetted with an unfilled resin first . After removing the excess resin, fibers will be covered with a very thin layer of flowable composite X-tra base . After that, fibers will be bonded immediately against the peripheral missing walls and cured for 20 seconds. Then a bulk-fill flowable resin composite lining X-tra base will be applied in approximately 4 mm thick in bulk increments as needed to fill the cavity 2 mm short of the occlusal cavosurface and each increment will be light cured for 20 s. The remaining occlusal part of the cavity will be restored with a universal hybrid resin composite, GrandioSO . The shade of the composite will be selected according to the teeth to be restored. All cavities will be restored with open-sandwich technique (Deliperi, et al. 2017).
Study: NCT05804383

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-984923
Description: Capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-984923
Description: Capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-984923
Description: Capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-984923
Description: Capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-984923
Description: Capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-984923
Description: Capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Capsules
Study: NCT04681872

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Destruction of Marshall bundles
Description: Destruction of Marshall bundles by ethanol 96% infusion (2 separate injections of 5ml on 1 minute each) followed by ablation of the distal coronary sinus bundles, the ridge and the saddle.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary veins isolation
Description: Achievement of a wide disconnection of the right and left pulmonary veins.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary veins isolation
Description: Achievement of a wide disconnection of the right and left pulmonary veins.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Linear ablation in the left and right atria
Description: Ablation of the mitral, the roof, and the cavo-tricuspid isthmus
Study: NCT05615727

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zolpidem
Description: zolpidem 10 mg and intranasal saline 0.02 ml/kg

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: a placebo oral tablet and intranasal saline at 0.02 ml/kg
Study: NCT05450419

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: 8pc (576,000 IU/40ml) vitamin D3 on week 1, then 1pc (72,000 IU/5ml) vitamin D3 on week 2, week 3 \& week 4.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: 8pc placebo on week 1, then 1pc placebo on week 2, week 3 \& week 4.
Study: NCT05917756

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobilization with Movement (MWM) and Tailored Therapeutic Exercise Program
Description: The intervention consists of MWM techniques targeting the cervical and thoracic spine, and the first rib, applied by a certified physiotherapist for 8 weeks, 2 sessions per week, each session lasting 45 minutes. The intervention also includes a tailored therapeutic exercise program for the patients, comprising postural correction, stretching, and strengthening exercises. This intervention will be compared to conventional physiotherapy in the control group.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physiotherapy
Description: Conventional physiotherapy, including manual therapy (soft tissue mobilization, joint mobilization, and nerve gliding techniques) for 8 weeks, 2 sessions per week, each session lasting 45 minutes, combined with a tailored therapeutic exercise program (including postural correction, stretching, and strengthening exercises).
Study: NCT06206408

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fezolinetant
Description: oral
Study: NCT06036186

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BaroPacing treatment
Description: BaroPacing for the first 3 weeks (day 8 to day 28) and then crossover to standard treatment for another 3 weeks (day 29 to day 49).
Study: NCT06206408

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fezolinetant
Description: oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: oral

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral
Study: NCT06036186

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard treatment
Description: Individual Standard treatment as prescribed by the Physician to each subject for the first 3 weeks (day 8 to day 28) and then crossover to BaroPacing for another 3 weeks (day 29 to day 49).
Study: NCT06329739

Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical examinations and clinical scales administration
Description: Psychometric assessment of cognitive and behavioral outcomes

Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical examinations and clinical scales administration
Description: Psychometric assessment of cognitive and behavioral outcomes
Study: NCT05209789

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HUGS
Description: Group therapy with the participation of two therapist positively encouraging mother-baby interactions in a non-judgmental manner

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Playtime
Description: Very little intervention from the therapists
Study: NCT04804371

Intervention type: DRUG
Group type: OTHER
Intervention: F18-FDG
Description: Evaluate FDG uptake
Study: NCT03439956

Intervention type: PROCEDURE
Intervention: Transvaginal specimen extraction
Description: Previous transvaginal specimen extraction through posterior colpotomy.
Study: NCT06222931

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Triplanar vibrating platform
Description: Mechanical vibration emitted by triplanar vibrating platforms

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Side-alternating vibrating platform
Description: Mechanical vibration emitted by side-alternating vibrating platforms

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham vibration
Description: Simulated vibration
Study: NCT04652778

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Field Ablation (PFA) using the Centauri System
Description: cardiac ablation using pulsed electric field energy to cause pulmonary vein isolation; cavo-tricuspid isthmus (CTI) line ablation may be performed as needed
Study: NCT03917251

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Coronary flow and pressure measurement in patients with ventricular pacing
Description: Coronary flow and pressure measurement in patients with ventricular pacing

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Coronary flow and pressure measurement in patients with ventricular pacing
Description: Coronary flow and pressure measurement in patients with ventricular pacing
Study: NCT05568537

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pylarify Piflufolastat Flourine-18 (18F-DCFPyL)
Description: Piflufolastat F18 will first be given intravenously over about 5 seconds.
Study: NCT05386394

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active tDCS + Language Therapy
Description: Active tDCS stimulation will be delivered by a battery-driven constant current stimulator. The electrical current will be administered to a pre-specified region of the brain (inferior frontal gyrus). The stimulation will be delivered at an intensity of 2mA (estimated current density 0.04 milliamps (mA)/cm2; estimated total charge 0.048 Coulombs (C)/cm2) in a ramp-like fashion for a maximum of 20 minutes. Language therapy will be conducted in conjunction with stimulation and will target oral and written naming.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Active tDCS + Language Therapy
Description: Active tDCS stimulation will be delivered by a battery-driven constant current stimulator. The electrical current will be administered to a pre-specified region of the brain (inferior frontal gyrus). The stimulation will be delivered at an intensity of 2mA (estimated current density 0.04 milliamps (mA)/cm2; estimated total charge 0.048 Coulombs (C)/cm2) in a ramp-like fashion for a maximum of 20 minutes. Language therapy will be conducted in conjunction with stimulation and will target oral and written naming.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham tDCS + Language Therapy
Description: During sham stimulation, current will be administered in a ramp-line fashion but after the ramping the intensity will drop to 0 mA. Language therapy targeting oral and written naming will be administered during sham tDCS stimulation.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham tDCS + Language Therapy
Description: During sham stimulation, current will be administered in a ramp-line fashion but after the ramping the intensity will drop to 0 mA. Language therapy targeting oral and written naming will be administered during sham tDCS stimulation.
Study: NCT05626205

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PARO robot
Description: PARO is an advanced interactive robot. It allows the documented benefits of animal therapy to be administered to patients in environments such as hospitals and extended care facilities where live animals present treatment or logistical difficulties. PARO has five kinds of sensors: tactile, light, audition, temperature, and posture sensors, with which it can perceive people and its environment. PARO can learn to behave in a way that the user prefers, and to respond to its new name.
Study: NCT06191029

Intervention type: BEHAVIORAL
Intervention: Urdu translated cognitive failure questionnaire
Description: Urdu Translated version of cognitive failure questionnaire will be given to adults to fill it accordingly and then it's reliability and validity will be checked
Study: NCT05697614

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Valproic acid
Description: valproic acid is used for general epilepsy type, used in experimental group

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbamazepin
Description: carbamazepine is used for focal type epilepsy, used in experimental group

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenytoin
Description: phenytoin is used for both general or focal epilepsy in case valproic acid or carbamazepine is contraindicated, used in experimental group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lamotrigine
Description: lamotrigine is used for general epilepsy type, used in control group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clobazam
Description: clobazam is used for both general or focal epilepsy in case if lamotrigine or oxcarbazepine is not possible to be administered and is used particularly in myoclonic jerk , used in control group

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxcarbazepine
Description: oxcarbazepine is used for focal type epilepsy, used in control group
Study: NCT06461000

Intervention type: OTHER
Intervention: Survey
Description: online survey for participants
Study: NCT05123430

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Monitoring of the pressure of the middle left atrium
Description: During the MitraClip surgery, additional catheter is installed in order to monitoring the ppressure of the middle left atrium
Study: NCT05434169

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Arterial Blood Gas
Description: The procedure of arterial blood collection will be conducted in a seated position for all three groups. The patient is in a supine position, with the forearm comfortably placed on a small table. The needle used for blood collection is a 25 gauge needle without local anesthetic. This method of sampling is identical to the one used in daily practice in the Emergency department of Fribourg

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Arterial Blood Gas
Description: The procedure of arterial blood collection will be conducted in a seated position for all three groups. The patient is in a supine position, with the forearm comfortably placed on a small table. The needle used for blood collection is a 25 gauge needle without local anesthetic. This method of sampling is identical to the one used in daily practice in the Emergency department of Fribourg

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Arterial Blood Gas
Description: The procedure of arterial blood collection will be conducted in a seated position for all three groups. The patient is in a supine position, with the forearm comfortably placed on a small table. The needle used for blood collection is a 25 gauge needle without local anesthetic. This method of sampling is identical to the one used in daily practice in the Emergency department of Fribourg
Study: NCT06333704

Intervention type: BIOLOGICAL
Intervention: SPIKEVAX Bivalent
Description: No study drug will be administered during this study as this is an observational study.

Intervention type: BIOLOGICAL
Intervention: SPIKEVAX X
Description: No study drug will be administered during this study as this is an observational study.
Study: NCT05213520

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alternate Day Intermittent Energy Restriction
Description: It is a dietary intervention designed to alternate between full energy consumption on one day and 40% of daily energy requirement on the following day.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Reduced Calorie Diet
Description: It is a dietary intervention designed to reduce daily calorie intake by 500-1000 kcal below an individual's daily calorie needs.
Study: NCT05728268

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dose-dense nab-paclitaxel followed by EC
Description: dose-dense nab-paclitaxel followed by EC
Study: NCT06104332

Intervention type: DEVICE
Intervention: ProRhinel Naturel spray nasal/ Allergic rhinitis
Description: ProRhinel Naturel spray nasal: 21 days; 1 spray per nostril; 3 to 6 times per day
Study: NCT05729490

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Coronary computed tomography angiography
Description: All patients will be subjected to:~Two CT scans (coronary calcium scoring and angiography) using 128 or 160-row scanners with a slice thickness of 0.5 mm (Revolution Evo 128, GE Health care, Chicago, Illinois, USA) or (Aquilion 160, Canon Medical Systems, Tochigi, Japan). Calcium scoring will be performed with the use of prospective electrocardiographic gating with 400-ms gantry rotation, 120-kV tube voltage, and 300-mA tube current. For CTA, retrospective electrocardiographic gating will be used, with heart rate adjusted gantry rotations of 350 ms to 500 ms to enable adaptive multisegmented reconstruction.~Iopromide (Ultravist 370, Bayer AG, Berlin, Germany) is the intravenous contrast medium that will be used for CTA. Beta-blockers will be given if the resting heart rate is 70 beats/min.
Study: NCT05209529

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: olaparib
Description: olaparib 300 mg per os BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: olaparib
Description: olaparib 300 mg per os BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: durvalumab 1500 mg IV Q4 weeks
Study: NCT05970224

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ir-CPI
Description: Participants receive a single intravenous dose of Ir-CPI during 48 hours