TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06467630

Intervention type: PROCEDURE
Intervention: Preserving alveolar bone volume after tooth extraction
Description: * Visit 1: A periodontal or dental implant surgery is done aiming to preserve alveolar bone volume after extraction~* Visit 2 (10 days ± 4 days) - Early post-surgery follow-up~* V2bis (1 month +/- 1 week) - Early post-surgery follow-up~* Visit 3 (5 months ± 1 month) - Late post-surgery follow-up

Intervention type: PROCEDURE
Intervention: Alveolar crest reconstruction
Description: * Visit 1: A periodontal or dental implant surgery is done aiming to alveolar crest reconstruction~* Visit 2 (10 days ± 4 days) - Early post-surgery follow-up~* Visit 3 (5 months ± 1 month) - Late post-surgery follow-up

Intervention type: PROCEDURE
Intervention: Covering bone defects during immediate implant placement.
Description: * Visit 1: A periodontal or dental implant surgery is done aiming to cover bone defects during immediate implant placement.~* Visit 2 (10 days ± 4 days) - Early post-surgery follow-up~* Visit 3 (3 months ± 1 month) - Late post-surgery follow-up
Study: NCT05955989

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: soft lining of complete denture processed by 3 different techniques.
Description: soft lining for complete denture
Study: NCT06007586

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aprepitant Injection
Description: Two antiemetic groups use placebo,Dexamethasone and Ondansetron, Three antiemetic groups use Aprepitant,Dexamethasone and Ondansetron.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Aprepitant Injection
Description: Two antiemetic groups use placebo,Dexamethasone and Ondansetron, Three antiemetic groups use Aprepitant,Dexamethasone and Ondansetron.
Study: NCT04656587

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Philips Respironics V60 Non-invasive ventilator, BPAP
Description: Continuous albuterol will be administered through the BPAP circuit.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard Therapy
Description: Standard status asthmaticus therapy with continuous beta-agonist, steroids and oxygen as needed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Therapy
Description: Standard status asthmaticus therapy with continuous beta-agonist, steroids and oxygen as needed.
Study: NCT05475912

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group A, excercises
Description: Each group will receive treatment three times per week for 3 weeks total 7 sessions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group A, excercises
Description: Each group will receive treatment three times per week for 3 weeks total 7 sessions.
Study: NCT05174676

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Dextreme
Description: A unique robotic device capable of applying motor error enhancement forces during upper limb practice in a virtual environment. The forces stimulate the body's instinctive adaptive response, which does not require the use of cognition to correct the movement.~The setting of stroke patients in a simulated environment enhances patient motivation and participation. The completion of games (tasks) is a great indicator for the patients that they are progressing in the treatment and are on their way to recovery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dextreme
Description: A unique robotic device capable of applying motor error enhancement forces during upper limb practice in a virtual environment. The forces stimulate the body's instinctive adaptive response, which does not require the use of cognition to correct the movement.~The setting of stroke patients in a simulated environment enhances patient motivation and participation. The completion of games (tasks) is a great indicator for the patients that they are progressing in the treatment and are on their way to recovery.
Study: NCT05512520

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Intensity-modulated radiotherapy concurrent with capecitabine
Description: All patients received external-beam radiation using intensity-modulated radiotherapy. The prescribed dose is 45 to 50.4Gy in 25 to 28 fractions, concurrently with 2 cycles of capecitabine tablets (825mg/m2) for two weeks.
Study: NCT04941482

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Periodic health check program for post-stroke
Description: The stroke survivors will be assessed their physical and mental health, recurrence risks, and harmful behaviors at 0, 1, 3, and 6 months by specific scales.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Periodic health check program for post-stroke
Description: The stroke survivors will be assessed their physical and mental health, recurrence risks, and harmful behaviors at 0, 1, 3, and 6 months by specific scales.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guiding the appropriate rehabilitation exercises
Description: The appropriate rehabilitation exercises will be designed and guided for each patient and they will be followed up by the daily online report.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Motivational Interviewing will carry out on post-stroke patients in the first three months (one time per week in the first month and one time per the second and third month). This intervention method aims to discover and resolve patient's conflicts by a standardized communication skill to improve their mental health and change negative behaviors.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Functional near-infrared spectroscopy
Description: The fNIRS devices as an effective monitoring and therapeutic tool, evaluating the evolution of neural activity and stroke rehabilitation and recovery. Moreover, the cortex hemodynamic measure by fNIRS may detect early various mental disorders such as depression, anxiety, schizophrenia... through cognitive tasks.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Functional near-infrared spectroscopy
Description: The fNIRS devices as an effective monitoring and therapeutic tool, evaluating the evolution of neural activity and stroke rehabilitation and recovery. Moreover, the cortex hemodynamic measure by fNIRS may detect early various mental disorders such as depression, anxiety, schizophrenia... through cognitive tasks.
Study: NCT06332976

Intervention type: OTHER
Intervention: Completion of questionnaires
Description: Completion of questionnaires at the time of study entry
Study: NCT04641741

Intervention type: DRUG
Intervention: Mepolizumab 100 MG
Description: Discovery of predictive/prognostic biomarkers of response to mepolizumab using flow cytometry, transcriptomic, and proteomic technologies.
Study: NCT05742126

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK36273
Description: Multiple continuous IV infusion ascending doses for 5 days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Heparin sodium injection
Description: Matching positive control
Study: NCT05657236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: medical treatment
Description: traditional medical treatment and regular follow-up

Intervention type: OTHER
Group type: OTHER
Intervention: medical treatment
Description: traditional medical treatment and regular follow-up

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: plyometric exercise
Description: Each session starts with a 5-minute warm-up of flexibility exercises (active range motion and stretching exercises).The main plyometric exercise set will be applied for 20-30 minutes and consisted of 10 exercises directed at the lower body that gradually progress by increasing the set/repetition number in two exercise blocks, each continue for 1 month .The cool down period is 5 minutes and includes walking at self-preferred speed and static stretches of the major muscle groups.
Study: NCT05258331

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: CT303
Description: 1. Cohort 1 : Single-dose administration, intravenous injection~   * Dose 1(Starting dose) : 1.0\*10\^6 cells/kg~  * Dose 2 : 2.0\*10\^6 cells/kg~  * Dose 3 : 3.0\*10\^6 cells/kg~2. Cohort 2 : Multiple-dose administration, intravenous injections (Week 0, Week 4)~   * Dose 1(Starting dose) : 1.0\*10\^6 cells/kg~  * Dose 2 : 2.0\*10\^6 cells/kg~  * Dose 3 : 3.0\*10\^6 cells/kg
Study: NCT05857826

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: soft tissue release
Description: Patient will be asked to lie in hook lying position using a clean glove will apply some water based lubricant gently sweep vaginal muscle from superficial to deep until find a trigger point press it and release it using circle motion for 1 to 2 minute until the trigger point is completely released.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: soft tissue release
Description: Patient will be asked to lie in hook lying position using a clean glove will apply some water based lubricant gently sweep vaginal muscle from superficial to deep until find a trigger point press it and release it using circle motion for 1 to 2 minute until the trigger point is completely released.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: vaginal dilators
Description: Vaginal dilators will be used according to the patient's condition starting from small sizes to the wider ones.
Study: NCT05536726

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 608 Q2W
Description: 608 160 mg at week 0 + 80 mg Q2W ( 6 cycles) +80 mg Q4W during maintenance period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 608 Q4W
Description: 608 160 mg Q4W ( 3 cycles) +160 mg Q8W during maintenance period

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive Placebo at pre-specified time points to maintain the blinding of the Investigational Medicinal Products.
Study: NCT04614493

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SonoCloud-9 (SC9) device
Description: daily temozolomide (TMZ) during Radiation, followed by 6 months of adjuvant TMZ (5 days/months) with 6 concomitant Blood Brain Barrier opening sessions by ultrasound~+ 9 Blood Brain Barrier opening sessions by ultrasound without any associated drug

Intervention type: DRUG
Group type: OTHER
Intervention: Temozolomide according Stupp protocol
Description: daily temozolomide (TMZ) during Radiation, followed by 6 months of adjuvant TMZ (5 days/months)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide according Stupp protocol
Description: daily temozolomide (TMZ) during Radiation, followed by 6 months of adjuvant TMZ (5 days/months)
Study: NCT05001711

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aria CV Acute PH System
Description: The Aria CV Acute PH System is indicated for evaluation of hemodynamic responses (e.g. pulmonary arterial compliance, cardiac output, and effective arterial elastance) to an intravascular Balloon catheter temporarily placed in the pulmonary artery in symptomatic adult patients with WHO Group 2 or WHO Group 3 pulmonary hypertension and right ventricular dysfunction.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aria CV Acute PH System
Description: The Aria CV Acute PH System is indicated for evaluation of hemodynamic responses (e.g. pulmonary arterial compliance, cardiac output, and effective arterial elastance) to an intravascular Balloon catheter temporarily placed in the pulmonary artery in symptomatic adult patients with WHO Group 2 or WHO Group 3 pulmonary hypertension and right ventricular dysfunction.
Study: NCT05211076

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music Group
Description: The Introductory Information Form will be filled in by researcher using face-to-face interview technique.It will be ensured that the mother fills the State Anxiety Scale with her own statement.On the 1st day of the post-op,mothers will be able to listen to Classical Turkish Music works in the forms of Saz Semaisi,Peşrev,Medhal in Rast,Uşşak,Kürdi,Muhayyer makams for 30 minutes via their phone at 11:00am.~While the mother continues to listen to the music,at the 16th minute,the researcher will manually milk the mother for at least 15 minutes until milk comes out.At the end of the milking process,the milk accumulated in the container will be measured by the researcher with injector,recorded in the Breast Milk Follow-up Form.At the end of the music session,it will be ensured that the mother fills in the State Anxiety Scale with her own statement.~The same procedure will be applied to the mother atb05:00pm.This process will be carried out 8 times in total,at 11:00am and 05:00pm for 4days.
Study: NCT06260852

Intervention type: DIAGNOSTIC_TEST
Intervention: Diagnostic Test: Visual Acuity Assessment
Description: Uncorrected visual acuity for nine distances (25, 28, 33, 40, 50, 60, 100, 200, 300 cm) examination via a Democritus Digital Acuity \& Reading Test (DDART).
Study: NCT05211076

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Marmet Technique Group
Description: Consent will be obtained from those who agree to participate in the study. The Introductory Information Form will be filled by the researcher using face-to-face interview technique.~It will be ensured that the mother fills the State Anxiety Scale with her own statement.~The Marmet Technique will be applied to the mothers at 11:00am for 20-30 minutes by the researcher.~At the end of the milking process performed in accordance with the technique, the milk accumulated in the container will be measured with an injector and recorded in the Breast Milk Follow-up Form.~Then, it will be ensured that the mother fills in the State Anxiety Scale with her own statement.~At 05:00pm, the same procedure will be applied to the mother. At the end of the 4th day, the satisfaction of the mother will be evaluated on the Mother Satisfaction Evaluation Scale.This process will be carried out 8 times in total,at 11:00am and 05:00pm for 4days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control group
Description: The Introductory Information Form will be filled by the researcher using face-to-face interview technique.It will be ensured that the mother fills the State Anxiety Scale with her own statement.The mothers will milk the mother manually by the researcher at 11:00am for at least 15 minutes until the milk does not come.~At the end of the milking process, the milk accumulated in the container will be measured with an injector and recorded in the Breast Milk Follow-up Form in ml.~Then, it will be ensured that the mother fills in the State Anxiety Scale with her own statement. At 05:00pm, the same procedure will be applied to the mother.~At the end of the 4th day, the satisfaction of the mother will be evaluated on the Mother Satisfaction Evaluation Scale.This process will be carried out 8 times in total,at 11:00am and 05:00pm for 4days.
Study: NCT06332976

Intervention type: OTHER
Intervention: Completion of questionnaires
Description: Completion of questionnaires at the time of study entry

Intervention type: OTHER
Intervention: Completion of questionnaires
Description: Completion of questionnaires at the time of study entry
Study: NCT04988152

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: sotrovimab
Description: sotrovimab IV infusion, single dose
Study: NCT05554458

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ChildTaks+ intervention
Description: The ChildTalks+ Intervention ChildTalks+ is a preventive intervention originally developed in the Netherlands, targeting children up to 18 years of age. It has been implemented in Norway, Italy, and Portugal. It has a clear and well-described theoretical basis focusing on psychoeducation. Its key strategy is to provide feasible and replicable interventions to improve the quality of life of families where parents are affected by a mental disorder.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ChildTaks+ intervention
Description: The ChildTalks+ Intervention ChildTalks+ is a preventive intervention originally developed in the Netherlands, targeting children up to 18 years of age. It has been implemented in Norway, Italy, and Portugal. It has a clear and well-described theoretical basis focusing on psychoeducation. Its key strategy is to provide feasible and replicable interventions to improve the quality of life of families where parents are affected by a mental disorder.
Study: NCT00689806

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lovastatin
Description: Lovastatin 20 mg extended release (or placebo) by mouth once daily for weeks 1-4. Liver function test will be checked at week 4 follow up visit. If LFTs are not \> 3 times the upper limit of normal, then the subject will have the dose of extended release lovastatin increased to 60 mg once a day for weeks 4-12

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo by mouth once daily for weeks 1-4.
Study: NCT04988152

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo to Biologic
Description: Sterile 0.9% (w/v) sodium chloride solution

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: sotrovimab
Description: Sotrovimab IM injection, single dose

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo to Biologic
Description: Sterile 0.9% (w/v) sodium chloride solution
Study: NCT05821660

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Five-day hypocaloric and ketogenic programme
Description: Dietary intervention
Study: NCT05848531

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clonidine
Description: Comparing Clonidine with Morphine PCIA for the treatment of Vaso-Occlusive crisis in Sickle Cell disease patient
Study: NCT06209814

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional denture
Description: Patients in this group received conventional maxillary and mandibular complete dentures. The patients used these dentures for 45 days. Then, the conventional maxillary denture was replaced by open faced denture with soft acryl resin wing.
Study: NCT05922618

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: I-One
Description: I-ONE® is a medical device certified by the Ministry of Health as a Medical Device (risk class II A) for the treatment of inflammatory and degenerative tissue pathologies. The device consists of a signal generator and an applicator, called a solenoid. The solenoid will be placed on the joint, not necessarily in direct contact with the skin. The device works with a rechargeable battery and is equipped with an hour counter to assess patient compliance.~Treatment with I-ONE® therapy will start within 3-7 days of recruitment, will last 6 hours a day and will be maintained for 60 days. The treatment will be carried out at home and the device will be delivered directly to the patient's home by courier.
Study: NCT04763434

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dexamethasone; dexmedetomidine; ropivacaine
Description: Ultrasound-guided multilevelTPVB is performed at the end of lobectomy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dexamethasone; dexmedetomidine; ropivacaine
Description: Ultrasound-guided multilevelTPVB is performed at the end of lobectomy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dexamethasone; dexmedetomidine; ropivacaine
Description: Ultrasound-guided multilevelTPVB is performed at the end of lobectomy
Study: NCT05964192

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: The theta burst stimulation (TBS) technique consists in administering bursts of transcranial magnetic stimulation (TMS) at very high frequency (50Hz) for 5 minutes (3 pulses of stimulation given at 50 hz; 10 bursts/1 s train; inter-train interval : 8 s; number of trains : 30; 100% resting motor threshold; number pulses/session : 900). Total number of sessions : 20 sessions (single daily session).
Study: NCT05288023

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Azithromycin for Oral Suspension
Description: Azithromycin will be administered as a single dose in oral suspension form for children (up to the maximum adult dose of 1g).~Dosage will be calculated by age for children aged 1-5 months. For children 6-59 months of age, height-based dosing will be used via height-stick approximation as currently performed by Niger's trachoma program.
Study: NCT05690087

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine
Description: intravenous lidocaine 2% bolus of 1.5 mg/kg over 5 min before induction of anesthesia followed by lidocaine infusion at 1.5 mg/kg/h intraoperatively until desufflation

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: sodium chloride 0.9% solution
Description: intravenous sodium chloride 0.9% solution volume matched bolus and infusion.
Study: NCT06437496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-AAZTA-093
Description: Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-AAZTA-093. Tracer doses of 68Ga-AAZTA-093 will be used to image lesions of prostate cancer by PET/CT.
Study: NCT06446583

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chewing sugar-free gum
Description: Upon arrival at the preoperative preparation room, patients begin chewing sugar-free gum provided by the preoperative nurse. They continue chewing until they enter the operating room (for at least 15 minutes). Before entering the operating room, it is confirmed that the gum has been discarded.
Study: NCT06373003

Intervention type: OTHER
Intervention: Diagnostic accuracy
Description: To assess the diagnostic accuracy of non-criteria aPL (anti-vimentin/cardiolipin and anti-phosphatidylserine/prothrombin) in identifying APS in patients with thrombosis/ recurrent adverse pregnancy outcomes

Intervention type: OTHER
Intervention: Diagnostic accuracy
Description: To assess the diagnostic accuracy of non-criteria aPL (anti-vimentin/cardiolipin and anti-phosphatidylserine/prothrombin) in identifying APS in patients with thrombosis/ recurrent adverse pregnancy outcomes
Study: NCT06437496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-PSMA-11//68Ga-PSMA-617
Description: Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-PSMA-11//68Ga-PSMA-617. Tracer doses of 68Ga-PSMA-11/68Ga-PSMA-617 will be used to image lesions of prostate cancer by PET/CT.
Study: NCT05269498

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CORTEXPLORER MED
Description: The CORTEXPLORER MED system is a platform that enables surgical navigation using real-time radiological images of patients. The application software formats patient-specific computed tomography or magnetic resonance images taken before surgery. These are displayed on the screen and through mixed reality from different perspectives (axial, sagittal, coronal, diagonal). Before surgery, the surgeon can then create, save and simulate the course along one or more surgical trajectories. As a visualization aid, the surgeon can also create and edit one or more 3D models of the anatomy. During surgery, the system tracks the position of specific surgical instruments in or on the patient's anatomy and continuously updates the position of the instruments on these images.