TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06277063

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous auricular vagus nerve stimulation
Description: The vagus nerve's auricular branch is primarily distributed in the tragus, tragus sulcus, and concha cavity. It can activate the nucleus tractus solitarius through the vagus afferent fibers, thereby activating various areas of the vagus nerve in the central nervous system. This stimulation technique involves applying a constant current of around 2-3mA to the epidermal terminals of the ear using an electrode. It aims to regulate the vagus nerve, modulate the autonomic nervous system, release neurotransmitters, improve cerebral blood flow, and alleviate headache symptoms. In the implementation, non-invasive transcutaneous vagus nerve stimulation was performed by having the subject wear a vagus stimulator and adjusting the appropriate stimulation intensity.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous auricular vagus nerve stimulation
Description: The vagus nerve's auricular branch is primarily distributed in the tragus, tragus sulcus, and concha cavity. It can activate the nucleus tractus solitarius through the vagus afferent fibers, thereby activating various areas of the vagus nerve in the central nervous system. This stimulation technique involves applying a constant current of around 2-3mA to the epidermal terminals of the ear using an electrode. It aims to regulate the vagus nerve, modulate the autonomic nervous system, release neurotransmitters, improve cerebral blood flow, and alleviate headache symptoms. In the implementation, non-invasive transcutaneous vagus nerve stimulation was performed by having the subject wear a vagus stimulator and adjusting the appropriate stimulation intensity.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcutaneous auricular vagus nerve stimulation
Description: The subjects in the sham stimulation group will wera a stimulator with the same appearance as the experimental group. However, the electrode of the stimulator will be located near the auricle and earlobe, and the intensity of the stimulator will be adjusted.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcutaneous auricular vagus nerve stimulation
Description: The subjects in the sham stimulation group will wera a stimulator with the same appearance as the experimental group. However, the electrode of the stimulator will be located near the auricle and earlobe, and the intensity of the stimulator will be adjusted.
Study: NCT06503809

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ketogenic Diet
Description: Participants will consume a very-low-carbohydrate ketogenic diet for 26 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Diet
Description: Participants will consume an American Diabetes Association-recommended standard diet for 26 weeks.
Study: NCT05905588

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hydrogen-rich water
Description: Patients drink 600mL hydrogen-rich water per day by applying hydrogen-rich water cup (Qingdao Haizhisheng Corp.,LTD, Qingdao, China) for 12 weeks. The dissolved hydrogen concentration is 5 ppm.
Study: NCT04967677

Intervention type: DIAGNOSTIC_TEST
Intervention: Nine Hole Peg Test, Purdue Pegboard Test, Box and Block Test
Description: At first, each person will be asked to fill in the questionnaire. Than he/she will be tested by the Nine Hole Peg Test, Purdue Pegboard Test and the Box and Block Test according to the Czech version of extended manuals for those tests. Audio recording of verbal instructions will be used.
Study: NCT06374186

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Intervention with financial rewards and coaching
Description: Participants will receive variable financial incentives based on their engagement with the continuous glucose monitor and meeting diabetes treatment goals. In addition, they will participate in three motivational interviewing sessions focused on their diabetes management. Participants will continue to receive their diabetes treatment as usual.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants will only receive a continuous glucose monitor, which they may engage with as desired and no further intervention. Participants in the control group will continue to receive their diabetes treatment as usual.
Study: NCT06090760

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: Mindfulness is paying attention in a particular way: on purpose, in the present moment, and non-judgmentally (Kabat-Zinn 1994, 4) and has five facets: awareness, nonjudgement, nonreactive, observe, and describe (Baer et al., 2006).
Study: NCT05905588

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Patients drink 600mL tap water per day by applying analogue cup for 12 weeks. This cup has the same appearance as the hydrogen-rich water cup, and the hydrogen-rich water and placebo water were indistinguishable. The dissolved hydrogen concentration is 0 ppm in placebo water.
Study: NCT06119113

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the wound infection at the 10th day post-op check-up among all groups
Description: Discharge, redness, increased temperature, and dehiscence were accepted as wound infection.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the wound infection at the 10th day post-op check-up among all groups
Description: Discharge, redness, increased temperature, and dehiscence were accepted as wound infection.
Study: NCT06213376

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Melodic Intonation Therapy
Description: Melodic Intonation Therapy uses intonation and melody to aid individuals with aphasia with producing words.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video Feedback Performance Review
Description: Participant will view recording to judge correct and incorrect productions of trained words and to identify motor techniques increasing intelligibility
Study: NCT06119113

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the wound infection at the 10th day post-op check-up among all groups
Description: Discharge, redness, increased temperature, and dehiscence were accepted as wound infection.
Study: NCT05963542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACT for tinnitus
Description: The intervention will be based on the ACT model and adjusted for tinnitus.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Customized sound therapy
Description: The music will be modulated through a smartphone app using a set program to generate customized tinnitus relieving sound.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Customized sound therapy
Description: The music will be modulated through a smartphone app using a set program to generate customized tinnitus relieving sound.
Study: NCT05144529

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nivolumab
Description: Nivolumab IV 240 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Nivolumab IV 240 mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ipilimumab
Description: Ipilimumab IV 1 mg/kg
Study: NCT05230823

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CR with added BWLT
Description: 12 week outpatient cardiac rehab (CR) program consisting of twice-weekly supervised exercise and risk factor modification (e.g. smoking cessation, support with medication). Concurrently, the patients will attend a weekly behavioural weight loss treatment (BWLT). Weekly goal-setting facilitated by the interventionist will focus on behavioural changes in nutrition and moderate calorie reduction while also emphasizing physical activity consistent with an individualized CR exercise prescription. Patients will track caloric intake, weekly exercise, weekly weight, and success/challenges with other health goals (e.g., challenging negative thoughts, body image, mindful eating, etc.) using a daily health diary. ASPIRE-AF will be delivered virtually to small groups (8-12 patients) by senior PhD students with advanced training in cognitive-behavioural therapy and motivational communication principles.
Study: NCT06029595

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental: CHF6001 3200 μg
Description: 800 μg/actuation - 2 inhalations of CHF6001 800 μg twice daily (BID) total daily dose 3200 μg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: CHF6001 Placebo
Description: 2 inhalations of CHF6001 matching placebo BID
Study: NCT05144529

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Ipilimumab IV 1 mg/kg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Evolocumab
Description: Evolocumab 14 mg subcutaneous injection
Study: NCT04808674

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive remediation program
Description: Evaluation of REmediation programs for patients suffering from mild cognitive deficits after Cancer
Study: NCT05451641

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Blood flow restriction resistance training
Description: The participants will receive a 2-week exercise training program (3 times per week). Each training session will consist of 3 resistance training exercises with two blood flow restriction devices (wide-rigid cuff and narrow-elastic band). For both arms, the participants will perform the same exercise with different BFR devices.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Blood flow restriction resistance training
Description: The participants will receive a 2-week exercise training program (3 times per week). Each training session will consist of 3 resistance training exercises with two blood flow restriction devices (wide-rigid cuff and narrow-elastic band). For both arms, the participants will perform the same exercise with different BFR devices.
Study: NCT05489770

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Sambucol® Black Elderberry Original (Sambucus nigra) Liquid
Description: Sambucol® Black Elderberry Original (Sambucus nigra) Liquid has been used as a supplement since 1991 with no reports of adverse effects received by the Manufacturer.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for Sambucol® Black Elderberry Original (Sambucus nigra)
Description: Placebo for Sambucol® Black Elderberry Original (Sambucus nigra) Liquid Constituents: 70% (w/w) of glucose syrup, Flavouring agent: Elderberry Blossom
Study: NCT05888103

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inclisiran
Description: Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran\*) in 1.5 mL

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo for Inclisiran
Description: Matching s.c. placebo in 1.5 mL
Study: NCT06119113

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups
Description: The cosmetic outcome of wound site scar healing was evaluated with two different scales. The Patient and Observer Assessment Scale (POSAS) is a questionnaire developed to assess scar quality. The investigator scores six items: vascularization, pigmentation, thickness, surface roughness, elasticity, and surface area. The participant scores six items: pain, itching, color, thickness, relief, and flexibility. All items are scored on a 10-point multiple scale; A score of 1 is given when the scar characteristic is similar to 'normal skin' and a score of 10 is given when it reflects the 'worst scar'. All items are summed to determine the total scar score; a higher score represents worse scar quality. The Vancouver scar scale (VSS) consists of four variables: vascularity, height (thickness), elasticity and pigmentation. The total score ranges from 0 to 14, with a score of 0 reflecting normal skin.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups
Description: The cosmetic outcome of wound site scar healing was evaluated with two different scales. The Patient and Observer Assessment Scale (POSAS) is a questionnaire developed to assess scar quality. The investigator scores six items: vascularization, pigmentation, thickness, surface roughness, elasticity, and surface area. The participant scores six items: pain, itching, color, thickness, relief, and flexibility. All items are scored on a 10-point multiple scale; A score of 1 is given when the scar characteristic is similar to 'normal skin' and a score of 10 is given when it reflects the 'worst scar'. All items are summed to determine the total scar score; a higher score represents worse scar quality. The Vancouver scar scale (VSS) consists of four variables: vascularity, height (thickness), elasticity and pigmentation. The total score ranges from 0 to 14, with a score of 0 reflecting normal skin.
Study: NCT05972902

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dydrogesterone
Description: Dydrogesterone molecular structure and pharmacologic effects are closely related to endogenous progesterone

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cetrorelix acetate
Description: GnRH antagonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triptorelin
Description: GnRH agonist
Study: NCT04558073

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Body Project (BP)
Description: The BP intervention offers discussions and exercises to make participants realize the cost of pursuing social ideals valuing thinness. This produces cognitive dissonance, a cognitive discomfort due to a contradiction between speech and beliefs, which motivates to modify one's beliefs. The curriculum includes discussions on techniques of the advertising industry and the unique ideal of beauty promoted worldwide, as well as on the costs of pursuing the thin-ideal. Participants are also challenged to try behaviours they avoid because their appearance bother them. Societal activism actions are also discussed.
Study: NCT04558073

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Weight Program (HW)
Description: The HW intervention allows participants to make personalized changes in their diet and physical activity each week gradually, to aim for a health-ideal rather than a thin-ideal. The intervention is based on small changes, based on behavioural change techniques. Advice is given on what types of changes introduce to promote health, and how to implement changes sustainably. Difficulties are discussed in the group with a problem-solving approach. The last session introduces a long-term view of lifestyle change.
Study: NCT05758870

Intervention type: PROCEDURE
Intervention: surgical stabilization of low rib fratures
Description: surgical stabiliazation of rib fractures by internal fixation
Study: NCT05880381

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Group
Description: Patients allocated to the treatment group will undergo an intervention that comprises 3 weekly sessions of 60 minutes for 4 weeks with the VR prototype.

Intervention type: OTHER
Group type: OTHER
Intervention: Control Group
Description: The participants allocated to this group will do the formal standard care provided by the Gynecology- Obstetric service.
Study: NCT05813964

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TDF/FTC 300mg/200mg fixed-dose combination tablets
Description: Event-driven dosing regimen

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAF/FTC 25mg/200mg fixed-dose combination tablets
Description: Event-driven dosing regimen.
Study: NCT06530199

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Enamel matrix derivative
Description: connective tissue graft and Enamel matrix derivative in the defect area

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Enamel matrix derivative
Description: connective tissue graft and Enamel matrix derivative in the defect area
Study: NCT06434181

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beetroot Juice
Description: Beet-It Sports Shot, 70mL, containing 6.5 mmol nitric oxide (taking two shots per day in active group)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control
Description: Beet-It Placebo Shot, 70mL (taking two shots per day in placebo group)
Study: NCT00378781

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Heparin
Description: Heparin flush solution into CVC once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Minocycline-EDTA
Description: M-EDTA flush solution into CVC once daily.
Study: NCT05272475

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Chamomile Tea
Description: Chamomile tea bags consumed by subjects as described in study arms section.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Chamomile Extract Capsule
Description: Chamomile extract capsules consumed by subjects as described in Experimental: Chamomile Extract Capsule study arms section.
Study: NCT04884152

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Home Exercise Group
Description: Educational training program about bruxism and the other oral parafunctional activities in patients with myofascial temporomandibular disorders.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Telerehabilitation Group
Description: Telerehabilitation program combined with educational training program about bruxism and the other oral parafunctional activities in patients with myofascial temporomandibular disorders.
Study: NCT06457022

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Constraint Induced Movement therapy
Description: patient wears a restraint instrument in his unaffected hand, then applying massed practice to his affected upper extremity. The patient wears padded glove in his unaffected upper extremity for restraining the patient from using his unaffected upper extremity for about 3 hours per day including the treatment session and the home program. So, by this way the patient is reinforced to use his affected upper extremity during this period of time to achieve his activities of daily living. Finally, the total time, the patient spends it during the day wearing the glove should be recorded each day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dual task training in the form of cognitive - motor task
Description: Verbal fluency: Ask the hemiparetic patient to title many words of specific type as fruits, vegetable or animals. Mental tracking: as the hemiparetic patient to subtract serial 3 between number 90 and 100.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physiotherapy rehabilitation program
Description: Ultrasound on shoulder. Graduated active exercises for shoulder. Prolonged stretching for spastic muscles
Study: NCT04802421

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: alveolar recruitment manoeuver
Description: alveolar recruitment manoeuver are recommended during general anesthesia to prevent pulmonary atelectasis

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: alveolar recruitment manoeuver
Description: alveolar recruitment manoeuver are recommended during general anesthesia to prevent pulmonary atelectasis
Study: NCT06457022

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physiotherapy rehabilitation program
Description: Ultrasound on shoulder. Graduated active exercises for shoulder. Prolonged stretching for spastic muscles

Intervention type: OTHER
Group type: OTHER
Intervention: Conventional physiotherapy rehabilitation program
Description: Ultrasound on shoulder. Graduated active exercises for shoulder. Prolonged stretching for spastic muscles
Study: NCT06032624

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: combined ultra-sound guided femoral and sciatic nerve block.
Description: Femoral nerve block, The femoral area will be scanned behind the midpoint of the inguinal ligament and the depth of the image will be set at 3-5 cm, and a linear high frequency 8-12MHz) probe will be placed perpendicular to the course of the femoral nerve., the volume of 15 ml of bupivacaine will be injected to perform the block. Sciatic nerve block, A curvilinear low-frequency (3-9 MHz) probe will be used to do a scan of the sub-gluteal region below a line from the ischial tuberosity and greater trochanter which are seen as two hyperechoic bony prominences,A volume of 25 ml of bupivacaine will be injected to perform the block.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: combined ultra-sound guided femoral and sciatic nerve block.
Description: Femoral nerve block, The femoral area will be scanned behind the midpoint of the inguinal ligament and the depth of the image will be set at 3-5 cm, and a linear high frequency 8-12MHz) probe will be placed perpendicular to the course of the femoral nerve., the volume of 15 ml of bupivacaine will be injected to perform the block. Sciatic nerve block, A curvilinear low-frequency (3-9 MHz) probe will be used to do a scan of the sub-gluteal region below a line from the ischial tuberosity and greater trochanter which are seen as two hyperechoic bony prominences,A volume of 25 ml of bupivacaine will be injected to perform the block.
Study: NCT05758870

Intervention type: OTHER
Intervention: converstive treatment of low rib fratures
Description: chest wall fixation band
Study: NCT06408467

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aMMP-8 diagnostic test
Description: 40 patients
Study: NCT05018533

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAKC-02
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inhalation Solution