TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06443008

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Observation Group
Description: On the basis of myoelectric biofeedback treatment in the control group, the control group was trained alternately in each muscle group (triangle muscle, triceps brachii muscle group and forearm extensor muscle group). For example,After disinfection of the triangular, triceps and extensor muscles of the patient, the feedback electrode was attached to the area. The stimulation frequency was set at 50 Hz and the stimulation pulse width was set at 200 μs.During treatment, the patient is instructed to listen carefully to the device's password, drive the affected limb according to the specific password, and then perform tension and relaxation training.For each muscle group, the training time of each muscle group is about 0.5 h, 1 / d.In the later stage of treatment, the training intensity can be increased appropriately, so that the patient can carry out weight lifting during the feedback treatment, and listen to the password issued by the device to carry out muscle strength exercise.
Study: NCT05201937

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.
Study: NCT05806970

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Email Nudge
Description: An email to UCLA Health Cardiology clinic managers with a list of MRA-eligible HFrEF patients and a request to schedule or change cardiology appointments.
Study: NCT06036095

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: Inhalational maintenance of anesthesia group using sevoflurane

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Intravenous maintenance of anesthesia group using propofol
Study: NCT04597437

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanamivir
Description: Intravenous zanamivir

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: In the placebo group, participants will receive placebo normal saline solution intravenously every twelve hours for 5 days.
Study: NCT04440488

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ARALAST NP
Description: Partcipants will be randomized to receive ARALAST NP 60 or 120 mg/kg BW/week IV infusion for a total of 104 weeks.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ARALAST NP
Description: Partcipants will be randomized to receive ARALAST NP 60 or 120 mg/kg BW/week IV infusion for a total of 104 weeks.
Study: NCT06014645

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: The study group will be given a core stabilization program in addition to education.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The control group will receive post-operative cognitive training and will be encouraged to move.
Study: NCT06530810

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10382+Flumatinib
Description: Drug:HS-10382+Flumatinib HS-10382 is administered orally BID Drug:Flumatinib Flumatinib 400mg once daily
Study: NCT05925790

Intervention type: DIAGNOSTIC_TEST
Intervention: IL1RA Antibody Assay
Description: -The measurement of anti-interleukin-1 receptor antagonist (IL1RA) antibodies will be performed using the ELISA (Enzyme-Linked Immunosorbent Assay) method,as previously described \[Thurner, L., et al., IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination. N Engl J Med, 2022. 387(16): p. 1524-1527\].
Study: NCT05672875

Intervention type: DIAGNOSTIC_TEST
Intervention: Anthrax LF Dx System
Description: Lateral flow immunoassay for the detection of the LF biomarker in whole blood samples.
Study: NCT06132802

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients who received treatment involving ARS and arthrocentesis only
Description: A 5mm acrylic anterior repositioning splint (ARS) with maxillary coverage was crafted from alginate impressions. After arthrocentesis, the ARS was worn incrementally over six months, starting at two hours and reaching 14 hours daily. In the second week, wear time was continuous, increasing to 24 hours daily (excluding meals) until the sixth month. The ramp was removed in the seventh week. Follow-ups involved grinding the splint by 1mm every four weeks. Arthrocentesis included anesthesia, betadine prep, and using two 18-gauge needles to inject Ringer's lactate solution (100-200 cc) for joint lavage, freeing the disc by moving the lower jaw in various orientations.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients who received treatment involving ARS, arthrocentesis, and an I-PRF injection
Description: A 5mm acrylic anterior repositioning splint (ARS) was crafted from alginate impressions, secured with Adam's clasps on upper first molars. After arthrocentesis, patients wore the splint incrementally over six months, starting at two hours and reaching 24 hours daily (excluding meals). The ramp was removed in the seventh week, and follow-ups included grinding the splint by 1mm every four weeks until it reached 3mm, guided by articulating paper.~Arthrocentesis involved administering anesthesia, prepping the area with betadine, and using two 18-gauge needles to inject 2-3 ml of Ringer's lactate solution for joint lavage. The lower jaw was moved to free the disc and release fibrous tissue. I-PRF preparation included centrifuging collected blood for 3 minutes at 700 rpm, and the resulting I-PRF was injected into the superior joint space of the lavaged joints.
Study: NCT05676554

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: An Enhanced Psychological Mindset Session for Adolescents
Description: It is a ten-minute psychoeducation video (animation) delivered on the internet, followed by five minutes of stories from fictional students about how they used the concepts. Participants then complete three multiple choice questions aimed to assess their understanding and ability to apply concepts from the video, followed by 'letter of advice' task where participants have to give advice to a fictional younger student based on the information presented in the animation and videos.~The intervention itself was developed by Perkins et al (2021) based on promoting a growth mindset. It was deemed to be a feasible and acceptable tool to promote mental health (Perkins et al., 2021) in their feasibility trial.
Study: NCT06054711

Intervention type: OTHER
Group type: OTHER
Intervention: joint puncture
Description: Patients reporting complications such as pain hindering mobility or affecting quality of life, or any other symptoms suspecting prosthesis failure or infection will undergo joint fluid aspiration.
Study: NCT05338632

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Narcan 40 MG/ML Nasal Spray
Description: naloxone 4mg/0.1 mL intranasal spray, up to 4 doses intranasally, followed by 1ml 0.4 mg/ml naloxone hydrochloride intravenously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Narcan 40 MG/ML Nasal Spray
Description: naloxone 4mg/0.1 mL intranasal spray, up to 4 doses intranasally, followed by 1ml 0.4 mg/ml naloxone hydrochloride intravenously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naloxone Hydrochloride
Description: naloxone 0.4mg/ml, up to 4 doses 2mg intramuscularly, followed by 1ml 0.4 mg/ml naloxone hydrochloride intravenously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naloxone Hydrochloride
Description: naloxone 0.4mg/ml, up to 4 doses 2mg intramuscularly, followed by 1ml 0.4 mg/ml naloxone hydrochloride intravenously
Study: NCT05925790

Intervention type: DIAGNOSTIC_TEST
Intervention: IL1RA Antibody Assay
Description: -The measurement of anti-interleukin-1 receptor antagonist (IL1RA) antibodies will be performed using the ELISA (Enzyme-Linked Immunosorbent Assay) method,as previously described \[Thurner, L., et al., IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination. N Engl J Med, 2022. 387(16): p. 1524-1527\].

Intervention type: DIAGNOSTIC_TEST
Intervention: suPAR Testing
Description: -The quantitative determination of soluble urokinase plasminogen activator receptor (suPAR) levels in blood will be conducted using the commercially available CHORUS suPAR Extended kit (cod. 81414, DIESSE Diagnostica Senese S.p.A., Siena, Italy), based on the principle of the sandwich ELISA method.

Intervention type: DIAGNOSTIC_TEST
Intervention: suPAR Testing
Description: -The quantitative determination of soluble urokinase plasminogen activator receptor (suPAR) levels in blood will be conducted using the commercially available CHORUS suPAR Extended kit (cod. 81414, DIESSE Diagnostica Senese S.p.A., Siena, Italy), based on the principle of the sandwich ELISA method.
Study: NCT06306742

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Open-label placebo
Description: Light pressure manual therapy

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Osteopathic manipulative treatment
Description: Manual therapy
Study: NCT05964634

Intervention type: DIAGNOSTIC_TEST
Intervention: OCT imaging
Description: Image J or Spectralis OCT built-in software package was used to manually locate and measure the area and width of the temporal parapapillary atrophy.

Intervention type: DIAGNOSTIC_TEST
Intervention: OCT imaging
Description: Image J or Spectralis OCT built-in software package was used to manually locate and measure the area and width of the temporal parapapillary atrophy.
Study: NCT05694468

Intervention type: OTHER
Group type: OTHER
Intervention: Psychomotor Relaxation
Description: Psychomotor relaxation sessions.
Study: NCT06514859

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic repair of inguinal hernia
Description: Laparoscopic repair of inguinal hernia

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open repair of inguinal hernia
Description: Repair of inguinal hernia by open technique-mesh hernioplasty -
Study: NCT05162456

Intervention type: DIAGNOSTIC_TEST
Intervention: assessment of the anti-SARS-CoV-2 IgG antibody titer in 3-dose schedule
Description: evaluation of anti-SARS-CoV-2 IgG antibodies in patients after 2-dose vaccination schedule willing to receive a 3rd dose of vaccine

Intervention type: DIAGNOSTIC_TEST
Intervention: assessment of the anti-SARS-CoV-2 IgG antibody titer in 2-dose schedule
Description: evaluation of anti-SARS-CoV-2 IgG antibodies in patients after 2-dose vaccination schedule unwilling to receive a 3rd dose of vaccine
Study: NCT06462677

Intervention type: DIAGNOSTIC_TEST
Intervention: Babesia NAT
Description: Blood donors will be tested with Babesia NAT
Study: NCT05572931

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fu's Subcutaneous Needling(FSN)
Description: Insertion points are both sides of 1) inferior edge of the scapula; 2)the midpoint of inferior edge of the posterior superior iliac spine and the ischial tuberosity.~FSN (Trocar Acupuncture Needle, Nanjing FSN Medical Co. , Ltd, China.) ) is a solid needle with plastic cannula tube on the outside. Add on swaying movement (SM) and reperfusion approach (RA) after the needle inserting into the subcutaneous layer. The SM is a horizontal fan sway movement with the base of the needle for the fulcrum, The SM speed is 200 times in 2 minutes. Apply RA when performing SM. RA movement is hip extension in prone position with resistance by physician's hand for 10 seconds. And then rest for 10 seconds. Repeat 3 cycles. The same RA is performed over the other three insertion point.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: fine acupuncture needle
Description: (36G, 0.5 inch, Wujiang city cloud \& dragon medical device Co.,Ltd.) Only inserted to skin, not into the subcutaneous layer. No SM and RA.
Study: NCT04885608

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PReGe
Description: There will be two weekly sessions of 45 minutes, outdoors in outdoor fitness parks. The components of balance, gait, resistance, strength and elasticity will be worked on and breathing exercises will be performed. The sessions will be guided and dosed by physiotherapists, considering the level of perception of effort. Indications will be given to carry out other sessions of 60 to 120 minutes of therapeutic walking (minimum speed of 4 km/hour) during the week, to complete the 150-300 minutes per week of physical activity recommended by the WHO.
Study: NCT05880888

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Renuva
Description: Renuva® (MTF Biologics) is an injectable decellularized allograft adipose matrix (AAM) used to increase volume in adipose tissue.
Study: NCT06467721

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Self-adhesive silicone gel waterproof dressing
Description: Self-adhesive silicone gel waterproof dressing is used after artificial joint replacement surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sterile gauze dressing
Description: Sterile gauze dressing is used after artificial joint replacement surgery.
Study: NCT06519630

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rehabotics Physiotherapy
Description: The intervention will be consisted of sessions for participants in the intervention group which includes a repetition of each of the four Sollerman AR Games named, Wallet, Key, Jar, Screwdriver and one repetition of Balloon Pop. Participants will interact with the AR Box and Block Test (BBT) and the serious games under controlled conditions. A clinician will be present throughout the whole session providing help if participants encounter any difficulties. Following the games, the clinician will initiate a stretching program using the Active Exoskeletal Aid, performing 3 sets of 10 repetitions on the finger flexors of the patient's hand. Each rehabilitation session will last 30 minutes and will be conducted three times a week. Similarly, the traditional physiotherapy training program will be prescribed for the control group and will be consisted of sessions lasting 30 minutes per day, three days per week. Both programs duration will be five weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Physiotherapy
Description: Similarly, the hand functional training program prescribed for the control group consisted of sessions lasting 30 minutes per day, three days per week. Both programs lasted for five weeks and were designed by two clinical experts.
Study: NCT05267717

Intervention type: OTHER
Intervention: Non-interventional study, all patients being tested with AG Pregnolia System to assess the values of the Cervical Stiffness
Description: Non-interventional study,

Intervention type: OTHER
Intervention: Non-interventional study, all patients being tested with AG Pregnolia System to assess the values of the Cervical Stiffness
Description: Non-interventional study,
Study: NCT05413109

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Coronary CT angiography
Description: A coronary CT angiography will be used to study the relationship between the PA and the LMCA and 4 radiological patterns will be considered:~1. Normal: minimum distance between the two vessels\> 1 mm;~2. Proximity: distance between the two vessels ≤1 mm without displacement or stenosis of the LMCA;~3. Dislocation: dislocation of the LMCA by the main branch of the PA with a take-off angle \<60 ° (the take-off angle is defined by the angle formed by the perpendicular to the aortic valve ring and the longitudinal axis of the LMCA);~4. Compression: stenosis of the LMCA ≥50% due to extrinsic compression by the PA.
Study: NCT05023083

Intervention type: OTHER
Intervention: Functional Status Questionnaire Urdu version
Description: The FSQ instrument translated into Urdu consists of only 34 items, main sections addressed physical function in the activities of daily living, psychological function, role function, social function and variety of performance measures.(8) Scores range from a 0 - 4, 1 - 4, and 1 - 6 scale per question depending on section. It increases reliability and patients ease and comfort. Total score range from 0 to 100 higher score represents the more severe condition.

Intervention type: OTHER
Intervention: Functional Status Questionnaire Urdu version
Description: The FSQ instrument translated into Urdu consists of only 34 items, main sections addressed physical function in the activities of daily living, psychological function, role function, social function and variety of performance measures.(8) Scores range from a 0 - 4, 1 - 4, and 1 - 6 scale per question depending on section. It increases reliability and patients ease and comfort. Total score range from 0 to 100 higher score represents the more severe condition.

Intervention type: OTHER
Intervention: Original Functional Status Questionnaire
Description: FSQ was developed to allow the comprehensive and efficient assessment of physical, psychosocial, social, and role functioning in ambulatory patients. It is a self-administered survey that takes approximately 15 min to complete. The results can be scored to produce a one-page report for clinicians to use in their practices. The responses to items within a scale are averaged and transformed to a scale with a potential range of 0 to 100.Higher score represents the more severe condition.

Intervention type: OTHER
Intervention: Original Functional Status Questionnaire
Description: FSQ was developed to allow the comprehensive and efficient assessment of physical, psychosocial, social, and role functioning in ambulatory patients. It is a self-administered survey that takes approximately 15 min to complete. The results can be scored to produce a one-page report for clinicians to use in their practices. The responses to items within a scale are averaged and transformed to a scale with a potential range of 0 to 100.Higher score represents the more severe condition.
Study: NCT05705843

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraosseous Vancomycin Injection
Description: • IO vancomycin is administered via an intraosseous cannulation device (Arrow EZ-IO; Teleflex, Morrisville, NC) in the OR after sterile prep and draping has occurred prior to skin incision (500mg in 150mL NS).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous Vancomycin
Description: IV Vancomycin will be started in the pre-operative period approximately 1 hour prior to incision (vancomycin dose weight-based at approximately 15mg/kg generally 1000-1750mg in 500mL NS).
Study: NCT05901623

Intervention type: OTHER
Intervention: 'Ages and Stages Questionnaries' (ASQ)
Description: ''ASQ' is a screening tool for assessing the development of infants and preschoolers in the areas of communication, fine motor, gross motor, problem-solving and personal-social development, and 'ASQ:SE' is a screening tool for social-emotional development

Intervention type: OTHER
Intervention: 'Ages and Stages Questionnaries' (ASQ)
Description: ''ASQ' is a screening tool for assessing the development of infants and preschoolers in the areas of communication, fine motor, gross motor, problem-solving and personal-social development, and 'ASQ:SE' is a screening tool for social-emotional development
Study: NCT05052840

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle endurance training (MET)
Description: Experimental group will be given MET Program, stretching \& strengthening exercises and Hot packs (for 15 minutes). MET program will include warm up, endurance and cool down exercises. The warm up and cool down period will be consisted of 5-minute walking, and 10 repetitions of stretching exercises. Endurance exercises will consist of 4 levels.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Treatment
Description: Conventional treatment group will be given hot packs (for 15 minutes) and Strengthening \& stretching exercise program including:~STRETCHING EXERCISES (lumbar extensor muscles, iliopsoas muscles, hamstring muscles, gastrocnemius muscles and pectoral muscles).~STRENGTHENING EXERCISES (rectus abdominus crunch, oblique crunch, pelvic elevation, single leg pelvic elevation, lumbal spine extension, on hands and knees position with the raise of one leg, on hands and knees position with the raise of opposite arm and leg). Each exercise will be repeated 10 times.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Treatment
Description: Conventional treatment group will be given hot packs (for 15 minutes) and Strengthening \& stretching exercise program including:~STRETCHING EXERCISES (lumbar extensor muscles, iliopsoas muscles, hamstring muscles, gastrocnemius muscles and pectoral muscles).~STRENGTHENING EXERCISES (rectus abdominus crunch, oblique crunch, pelvic elevation, single leg pelvic elevation, lumbal spine extension, on hands and knees position with the raise of one leg, on hands and knees position with the raise of opposite arm and leg). Each exercise will be repeated 10 times.
Study: NCT06378177

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LVGN6051 Monoclonal Antibody Injection
Description: LVGN6051 Monoclonal Antibody Injection:1 mg/kg or 2 mg/kg, every 3 weeks(Q3W) , on the first day of the treatment cycle for up to 2 years.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: toripalimab Injection
Description: toripalimab Injection: 240mg fixed dose,Q3W, on the first day of the treatment cycle for up to 2 years.
Study: NCT06251362

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sleep restriction
Description: Participants will experience a night of acute sleep restriction. During this night, they will sleep 3 hours less than usual.
Study: NCT06378177

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel injection
Description: paclitaxel Injection:5ml:100 mg/m2(80 mg/m2 or 60 mg/m2 can be used if necessary),Q3W,on the first and eighth day of the treatment cycle for up to 2 years
Study: NCT06134063

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xuanfei Baidu granule
Description: Xuanfei Baidu granule will be administered twice daily for 7 days on the basis of basic treatment

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Xuanfei Baidu granule Placebo
Description: Xuanfei Baidu granule Placebo will be administered twice daily for 7 days on the basis of basic treatment
Study: NCT04100213

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trier Social Stress Test
Description: The TSST-G is a psychological paradigm which combines high levels of social-evaluative threat and uncontrollability in a group setting. The TSST-G will proceed in groups of three to five participants (from the same diagnostic group). The TSST-G consists of three phases: a briefing; the psychological test itself, followed by a debriefing phase. Each phase will last 40, 20 and 60 minutes, respectively. The briefing and debriefing of the TSST-G will be conducted by experienced psychotherapists. The TSST-G itself will be conducted by personal unknown to the participants.