Study: NCT06663631

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: chlorpromazine and promethazine
Description: C+P were diluted to 50 ml saline solution and delivered intravenously at the beginning of endovascular thrombectomyat a velocity of 4ml/h. The whole period of drug delivery lasts for approximately 12h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: chlorpromazine and promethazine
Description: C+P were diluted to 50 ml saline solution and delivered intravenously at the beginning of endovascular thrombectomyat a velocity of 4ml/h. The whole period of drug delivery lasts for approximately 12h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: chlorpromazine and promethazine
Description: C+P were diluted to 50 ml saline solution and delivered intravenously at the beginning of endovascular thrombectomyat a velocity of 4ml/h. The whole period of drug delivery lasts for approximately 12h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: chlorpromazine and promethazine
Description: C+P were diluted to 50 ml saline solution and delivered intravenously at the beginning of endovascular thrombectomyat a velocity of 4ml/h. The whole period of drug delivery lasts for approximately 12h.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo group
Description: 50 ml saline solution was set as placebo and delivered intravenously at the beginning of endovascular thrombectomyat a velocity of 4ml/h. The whole period of drug delivery lasts for approximately 12h.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: endovascular thrombectomy
Description: All patients that are eligible for endovascular thrombectomy will receive this surgery in aim to remove thrombus and restore reperfusion.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endovascular thrombectomy
Description: All patients that are eligible for endovascular thrombectomy will receive this surgery in aim to remove thrombus and restore reperfusion.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endovascular thrombectomy
Description: All patients that are eligible for endovascular thrombectomy will receive this surgery in aim to remove thrombus and restore reperfusion.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endovascular thrombectomy
Description: All patients that are eligible for endovascular thrombectomy will receive this surgery in aim to remove thrombus and restore reperfusion.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endovascular thrombectomy
Description: All patients that are eligible for endovascular thrombectomy will receive this surgery in aim to remove thrombus and restore reperfusion.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: rt-PA
Description: All patients that are eligible for Intravenous thrombolysis will receive 0.9mg/kg rt-PA in aim to remove thrombus and restore reperfusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rt-PA
Description: All patients that are eligible for Intravenous thrombolysis will receive 0.9mg/kg rt-PA in aim to remove thrombus and restore reperfusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rt-PA
Description: All patients that are eligible for Intravenous thrombolysis will receive 0.9mg/kg rt-PA in aim to remove thrombus and restore reperfusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rt-PA
Description: All patients that are eligible for Intravenous thrombolysis will receive 0.9mg/kg rt-PA in aim to remove thrombus and restore reperfusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rt-PA
Description: All patients that are eligible for Intravenous thrombolysis will receive 0.9mg/kg rt-PA in aim to remove thrombus and restore reperfusion