TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05196269

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Artificial Intelligence and Digital Health Arm
Description: A previous large database repository of images having thousands of pre and postoperative photographs of breast cancer patients proposed for locoregional treatment with clinical and biometric data will be matched using artificial intelligence within the CANKADO platform. Patients proposed for breast cancer locoregional treatment will have access to the software installed, and they will have access to all the information about the type of treatment they will receive. All the questions and questionnaires will be filled out online, and they can visualise the expected outcome from excellent to poor.

Intervention type: DEVICE
Group type: OTHER
Intervention: Artificial Intelligence and Digital Health Arm
Description: A previous large database repository of images having thousands of pre and postoperative photographs of breast cancer patients proposed for locoregional treatment with clinical and biometric data will be matched using artificial intelligence within the CANKADO platform. Patients proposed for breast cancer locoregional treatment will have access to the software installed, and they will have access to all the information about the type of treatment they will receive. All the questions and questionnaires will be filled out online, and they can visualise the expected outcome from excellent to poor.
Study: NCT05502562

Intervention type: DRUG
Intervention: Oral semaglutide
Description: Participants will be treated with commercially available oral semaglutide according to local label and to routine clinical practice at the discretion of the treating physician. The decision to initiate treatment with commercially available oral semaglutide has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician based on local label before and independently from the decision to include the participant in this study.
Study: NCT05182372

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced dCBT-I
Description: Telehealth Coaching
Study: NCT06114615

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LiveCare
Description: Patient use LiveCare device to monitor their blood pressure and data is transmitted to dashboard.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Text Messages
Description: Patients also receive text messages after their PCI procedure for follow up appointment reminders, enrollment in cardiac rehab, and diet and exercise counseling.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Conventional Care
Description: No digital monitoring with LiveCare device and no text messages.
Study: NCT05506683

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MotoMeds pediatric telemedicine and medication delivery service (TMDS)
Description: The intervention is use of a pediatric TMDS. Eligible children experiencing acute illness are examined over the phone by EMTs who follow a set of clinical guidelines to triage, assess, and develop treatment plans for participants. To evaluate the TMDS and as a safety measure EMTs will also examine most participants in-person a their homes following the phone exam.
Study: NCT05604040

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Modifications
Description: Home BP monitoring with self-monitoring of emotions, diet, physical activity, with shared medical appointment program for lifestyle changes and coping skills
Study: NCT05734391

Intervention type: DIAGNOSTIC_TEST
Intervention: Routine Infection control
Description: routine part of hospital IPC activities
Study: NCT06410027

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain Neuroscience Education + Virtual Reality + Therapeutic Exercise
Description: Patients will receive 1-hour pain neuroscience education session + 30-minutes exposure to exercise with virtual reality + therapeutic exercise

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic Exercise
Description: Patients will receive therapeutic exercise
Study: NCT06093282

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ARCH
Description: ARCH is a 4-month health outreach intervention that includes the following components:~* Screening and referral to address social determinants of health~* A 12-session adaptation of Behavioral Activation Treatment for Depression~* Weekly contacts from an outreach worker~* Optional resources aimed at promoting physical activity and weight management

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Health Outreach
Description: The Traditional Health Outreach comparator is a 4-month health outreach intervention that includes the following components:~* Screening and referral to address social determinants of health~* Support calls from an outreach worker at least once every 3 weeks
Study: NCT06453044

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study: NCT04973904

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: IV infusion
Study: NCT06453044

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT or PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mosunetuzumab
Description: Given SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Polatuzumab Vedotin
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary Studies
Study: NCT03365414

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Albumin (Human) 5%, USP
Description: Albumin (Human) 5%, USP. Intravenous Solution. Plasma Substitute/Blood Derivative

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Albumin (Human) 5%, USP
Description: Albumin (Human) 5%, USP. Intravenous Solution. Plasma Substitute/Blood Derivative

Intervention type: DRUG
Group type: OTHER
Intervention: Normal Saline 0.9% Infusion Solution Bag
Description: Placebo Normal Saline 0.9% Infusion Solution Bag.

Intervention type: DRUG
Group type: OTHER
Intervention: Normal Saline 0.9% Infusion Solution Bag
Description: Placebo Normal Saline 0.9% Infusion Solution Bag.
Study: NCT06333314

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: Anti-PD-1 monoclonal antibody

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: * mFOLFOX6 or FOLFIRI or XELOX regimen~* FOLFOX or XELOX or TFOX regimen~* FOLFIRINOX or gemcitabine-nab-paclitaxel or gemcitabine monotherapy.~* Cisplatin and gemcitabine cisplatin or CAPOX or mFOLFOX6.~* Etoposide-cisplatin-doxorubicin or mitotane~* Cisplatin and gemcitabine or carboplatin and paclitaxel~* Etoposide-cisplatin or etoposide-carboplatin~* Doxorubicin and ifosfamide or doxorubicin monotherapy or doxorubicin and trabectedin.
Study: NCT06406855

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BCI-TSCS
Description: BCI-TSCS therapy, completed 3-4 times per week, that will include activity-based training, with TSCS activated by BCI system detecting movement attempt.
Study: NCT05996575

Intervention type: OTHER
Intervention: fNIRS measurement
Description: Kernel Flow2 measurements.

Intervention type: OTHER
Intervention: fNIRS measurement
Description: Kernel Flow2 measurements.
Study: NCT00057200

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Telephone, videophone care
Study: NCT06116149

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: In-person health coach delivery of the GLB
Description: Delivery of 24 health coaching sessions in-person by health coaches over 1 year.~Standard delivery of 24-sessions of the Group Lifestyle Balance (GLB) behavioral intervention in WIC clinics. The GLB was adapted from the original Lifestyle Balance behavioral intervention used in the original Diabetes Prevention Program trial for use in community translation and group settings. It focuses on improving diet and physical activity and promoting moderate weight loss through health coaching on behavioral change, including self-monitoring of food intake, physical activity, and weight.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Technology-assisted health coach delivery of the GLB
Description: Delivery of 12 health coaching GLB sessions in-person by health coaches over one year; supplemental technology support, including tools for self-monitoring, health coach monitoring, asynchronous delivery of intervention materials, and asynchronous coach and group connection.~The GLB was adapted from the original Lifestyle Balance behavioral intervention used in the original Diabetes Prevention Program trial for use in community translation and group settings. It focuses on improving diet and physical activity and promoting moderate weight loss through health coaching on behavioral change, including self-monitoring of food intake, physical activity, and weight.
Study: NCT06128382

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OVX033
Description: One single administration intramuscularly on Day 1

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OVX033
Description: One single administration intramuscularly on Day 1

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OVX033
Description: One single administration intramuscularly on Day 1

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Saline solution
Description: One single administration intramuscularly on Day 1

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Saline solution
Description: One single administration intramuscularly on Day 1

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Saline solution
Description: One single administration intramuscularly on Day 1
Study: NCT04715191

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: CARE T cells
Description: Four different dosing schedules will be evaluated. The following dose levels will be evaluated:~DL0: 1x10\^7/m\^2 DL1: 3x10\^7/m\^2 DL2: 1x10\^8/m\^2 DL3: 3x10\^8/m\^2~The doses are calculated according to the actual number of GPC3-CAR transduced T cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytoxan
Description: Cyclophosphamide will be given at a dose of 500 mg/m2/day for 3 days given intravenously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludara
Description: Fludarabine will be given at a dose of 30 mg/m2/day for 3 days given intravenously.
Study: NCT06473064

Intervention type: OTHER
Group type: OTHER
Intervention: Benelli technique for nipple sparing mastectomy in surgical treatment of grade 3 and 4 gynecomastia
Description: .The Nipple areola complex (NAC )margins on both sides are marked as circular. -Around the initial circle, a second circle (external) was drawn 1 cm broader than the boundary.~* The skin was resected, with deepithelialization between the two circles.~* A transdermal incision was made through the border of the external circle.~  -. The breast tissue around the pedicle was lifted over the pectoral fascia and excised by preserving the NAC and the underlying breast pedicle~* The base of the mammary pedicle under the NAC was infixed at the farthest end of the mastectomy area by using 3/0 absorbable multifilament suture material~  * Hence, the space formed after mastectomy was filled with a breast pedicle located posterior to the NAC.~ * The closure of the circular deepithelialized area around the NAC with a diameter of 1 cm accomplished by using 4/0 absorbable monofilament suture material and the surgery was completed
Study: NCT06100588

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling
Description: Dry needling (DN) is a myofascial treatment technique, in which a thin, solid filiform needle is inserted directly into the MTrP. During dry needling, local twitch responses (LTR) can be elicited. These are involuntary contractions of muscle fibers, leading to muscle relaxation, an increase in blood flow,recovery of the muscle metabolism and thus a reduction of pain and stiffness.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: Manual therapy comprises stretching of muscles, mobilizations, traction and translation of vertebrae, Sustained Natural Apophyseal Glides (SNAG), dynamic soft tissue mobilization, Muscle Energy Techniques (MET) and home-exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual therapy
Description: Manual therapy comprises stretching of muscles, mobilizations, traction and translation of vertebrae, Sustained Natural Apophyseal Glides (SNAG), dynamic soft tissue mobilization, Muscle Energy Techniques (MET) and home-exercises.
Study: NCT06229626

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: intensive reeducation
Description: * 1 group physiotherapy session per week at the ICM or by videoconference from home for 6 weeks~* 2 sessions per week at home with video support sent by e-mail for 6 weeks
Study: NCT05323253

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DaRT seeds
Description: DaRT source will be inserted using preplanned radiotherapy parameters and reassessed by volumetric imaging 2-3 weeks after placement and then removed.
Study: NCT06173687

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The impedance measurement task using the Mobile Research App (MRA)
Description: Characterisation of impedance and real-world monitoring of hearing difficulty in range of listening environments.
Study: NCT06583668

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Story
Description: Listening and watching the therapeutic story in digital media
Study: NCT05928936

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Bicarbonate
Description: Participants take 650-1300 mg of sodium bicarbonate orally twice daily. Serum bicarbonate levels are measured at baseline and then every 2-4 weeks throughout the trial. Doses will be adjusted or held to avoid metabolic alkalosis.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Training
Description: Exercise training consists of progressive, interval-based Spin exercise on stationary bicycles three times per week for 12 weeks, led by a certified exercise physiologist. The duration of each session begins at 20 minutes and is increased by 1 to 2 minutes as tolerated to a goal of 45 minutes per session. Exercise intensity begins at low levels (50% of maximal heart rate reserve (HRR)) and increases by 5% every week to a goal of 75% maximal HRR. Each session includes a 5-min warm up, then an interval-based, work-out phase that includes steady up-tempo cadences, sprints, and climbs, followed by a 5-minute cool down.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Training
Description: Exercise training consists of progressive, interval-based Spin exercise on stationary bicycles three times per week for 12 weeks, led by a certified exercise physiologist. The duration of each session begins at 20 minutes and is increased by 1 to 2 minutes as tolerated to a goal of 45 minutes per session. Exercise intensity begins at low levels (50% of maximal heart rate reserve (HRR)) and increases by 5% every week to a goal of 75% maximal HRR. Each session includes a 5-min warm up, then an interval-based, work-out phase that includes steady up-tempo cadences, sprints, and climbs, followed by a 5-minute cool down.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Participants take placebo pills to match 650-1300 mg of sodium bicarbonate orally twice daily.
Study: NCT06365879

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CMAB007
Description: 300mg, SC, Q4W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Xolair
Description: 300mg, SC, Q4W
Study: NCT06473246

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CBD Isolate (25 mg/0.5 ml)
Description: 0.5 ml sublingually to be consumed after dinner, 30 min ± 5 mins before going to bed.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CBD Isolate (40 mg/0.5 ml)
Description: 0.5 ml sublingually to be consumed after dinner, 30 min ± 5 mins before going to bed.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CBD Isolate (50 mg/0.5 ml)
Description: 0.5 ml sublingually to be consumed after dinner, 30 min ± 5 mins before going to bed.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CBD Broad Extract (50 mg/0.5 ml)
Description: 0.5 ml sublingually to be consumed after dinner, 30 min ± 5 mins before going to bed.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.5 ml sublingually to be consumed after dinner, 30 min ± 5 mins before going to bed.
Study: NCT05052268

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XTX202
Description: XTX202 Monotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XTX202
Description: XTX202 Monotherapy
Study: NCT06237725

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutrition of Continuous
Description: The researcher will perform gastric residual volume (GRV) measurements with a syringe, abdominal circumference measurements, and distension assessments daily before starting enteral nutrition from the first day of initiation. They will also record vomiting/defecation frequency. Massage will be applied for 15 minutes. The same criteria will be measured and recorded. The application and measurements will be conducted twice a day for 10 consecutive days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutrition of Bolus
Description: The researcher will perform gastric residual volume (GRV) measurements with a syringe, abdominal circumference measurements, and distension assessments daily before starting enteral nutrition from the first day of initiation. They will also record vomiting/defecation frequency. Massage will be applied for 15 minutes. The same criteria will be measured and recorded. The application and measurements will be conducted twice a day for 10 consecutive days.
Study: NCT04973904

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: IV infusion
Study: NCT05416060

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dulce Digital Text-Based Education
Description: Participants will be enrolled in the digital texting platform, Dulce Digital in which they will receive on-going support via text messages for 6 months, derived from the Project Dulce curriculum. Topics include medication reminders, motivational prompts, nutrition and stress reduction tips and request to submit weekly blood glucose numbers.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Project Dulce Telehealth
Description: Project Dulce will consist of a group-based telehealth diabetes self-management education program consisting of a 5 -week curriculum delivered by a peer educator in English or Spanish. The curriculum provides skills and tools needed to adapt to a life with diabetes and change behaviors. The curriculum covers diabetes and its complications, the role of diet, exercise, and medication, and the importance of self-monitoring. It is presented over 5 weeks where participants learn and practice self-management skills, and help one another address family, cultural or health system barriers to managing your diabetes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Project Dulce Live
Description: Project Dulce will consist of a group-based diabetes self-management education program consisting of a 5 -week curriculum delivered by a peer educator in English or Spanish. The curriculum provides skills and tools needed to adapt to a life with diabetes and change behaviors. The curriculum covers diabetes and its complications, the role of diet, exercise, and medication, and the importance of self-monitoring. It is presented over 5 weeks where participants learn and practice self-management skills, and help one another address family, cultural or health system barriers to managing your diabetes.
Study: NCT05342025

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF
Description: PNF will be applied to the trunk and upper extremities combined with breathing, 3 times a week, 1 hour a day for 6 weeks. Breathing PNF patterns, pressure, and stretches will be applied inward and upwards into the rib cage so that they do not cause pain. Diaphragmatic stimulation will be performed on both sides with repeated contractions, hand contacts, and stabilization techniques. Facilitation techniques will be used to stimulate the intrinsic respiratory muscles. Again, with respect to inspiration, the patterns will be studied in neck extension, upper and lower trunk extension, and upper extremities flexion patterns. Neck flexion, upper and lower trunk flexion, and extension patterns of the upper extremities will be applied in relation to expiration. The physiotherapist will apply pressure and stretches to the chest wall and diaphragm for 20 seconds by giving verbal commands to the patient for the inspiration/expiratory phases.
Study: NCT06009653

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care
Description: Participants will meet with community health workers to receive general health information through individual check-ins.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally-tailored dietary and behavioral intensive lifestyle intervention
Description: Participants will meet with community health workers to receive information focused on healthy eating while still adhering to a culturally-tailored plant-forward diet.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally-tailored dietary and behavioral intensive lifestyle intervention
Description: Participants will meet with community health workers to receive information focused on healthy eating while still adhering to a culturally-tailored plant-forward diet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive placebo subcutaneous injections.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Participants will receive subcutaneous injections of tirzepatide that gradually increase up to 15 mg per week.
Study: NCT05342025

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Breathing exercises
Description: Breathing exercises: diaphragmatic breathing, thoracic expansion, pursed-lip breathing and respiratory control for 15 minutes a day, every day of the week.
Study: NCT06513845

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communal drumming recordings
Description: Segments (\~30 sec duration) of recordings taken from the music made during the previous drum circle. Segments will be categorized as highly synchronized

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communal drumming recordings
Description: Segments (\~30 sec duration) of recordings taken from the music made during the previous drum circle. Segments will be categorized as highly synchronized