TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05732012

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sexual Health Psychoeducation Program
Description: 62 adolescents were included in the study. Adolescents were assigned to intervention and control groups by randomization using simple numbers table. The intervention group was divided into 3 groups of 10 and included in a six-week psychoeducation program that lasted for one hour once a week, and 55 adolescents completed the program. The data on the sociodemographic characteristics of the adolescents constituting the sample were collected with the Participant Information Form. Data on the effectiveness of the psychoeducation program on sexual health knowledge and attitudes were collected with the Sexual Health Knowledge and Attitude Inventory before the psychoeducation, at the end of the training and at the 3rd month of follow-up.
Study: NCT05498545

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LUCAR-B68 cells product
Description: Before treatment with LUCAR-B68 cells, subjects will receive a conditioning regimen
Study: NCT00413101

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: epoetin beta [NeoRecormon]
Description: At a dose to achieve and maintain an Hb level of 120-135g/L
Study: NCT04230096

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low level laser therapy
Description: apply low level laser therapy on buccal surface of maxillary jaw on anterior segment for three minutes at every three weeks in fixed orthodontic patients in their regular follow up visits
Study: NCT05717595

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: fructose
Description: oral ingestion of fructose vs dextrose

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: fructose
Description: oral ingestion of fructose vs dextrose
Study: NCT05957133

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Multicomponent exercise without action observation.
Description: Different exercise modalities are integrated: Aerobic, mobility, strength, balance and coordination exercises.
Study: NCT05726123

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: The Exopulse Mollii Suit on a Fibromyalgia patient
Description: The present study consists of a comparative, randomized, controlled and clinical trial conducted to explore and compare the acute and chronic effects a treatment session with the Exopulse Mollii Suit, a treatment session with the Exopulse Mollii Suit combined with VR and a training session have on a Fibromyalgia patient.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Exopulse Mollii Suit on a Fibromyalgia patient
Description: The present study consists of a comparative, randomized, controlled and clinical trial conducted to explore and compare the acute and chronic effects a treatment session with the Exopulse Mollii Suit, a treatment session with the Exopulse Mollii Suit combined with VR and a training session have on a Fibromyalgia patient.
Study: NCT05957133

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multicomponent exercise associated with action observation
Description: Different exercise modalities are integrated: aerobic, mobility, strength, balance and coordination exercises carried out at all times by the physiotherapist and observed by the participants.
Study: NCT05726123

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Exopulse Mollii Suit on a Fibromyalgia patient
Description: The present study consists of a comparative, randomized, controlled and clinical trial conducted to explore and compare the acute and chronic effects a treatment session with the Exopulse Mollii Suit, a treatment session with the Exopulse Mollii Suit combined with VR and a training session have on a Fibromyalgia patient.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Exopulse Mollii Suit on a Fibromyalgia patient
Description: The present study consists of a comparative, randomized, controlled and clinical trial conducted to explore and compare the acute and chronic effects a treatment session with the Exopulse Mollii Suit, a treatment session with the Exopulse Mollii Suit combined with VR and a training session have on a Fibromyalgia patient.
Study: NCT05401773

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-time Quaking-Induced Conversion (RT-QuIC)
Description: RT-QuIC is increasingly used as diagnostic tools in synucleinopathies and has shown high sensitivity and specificity for the detection of α-synuclein seeds in CSF and tissue samples, including the olfactory mucosa in different patients' cohorts including Parkinson's patientients, patients with REM sleep behavior disorder (RBD), and patients with dementia with Lewy bodies.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-time Quaking-Induced Conversion (RT-QuIC)
Description: RT-QuIC is increasingly used as diagnostic tools in synucleinopathies and has shown high sensitivity and specificity for the detection of α-synuclein seeds in CSF and tissue samples, including the olfactory mucosa in different patients' cohorts including Parkinson's patientients, patients with REM sleep behavior disorder (RBD), and patients with dementia with Lewy bodies.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-time Quaking-Induced Conversion (RT-QuIC)
Description: RT-QuIC is increasingly used as diagnostic tools in synucleinopathies and has shown high sensitivity and specificity for the detection of α-synuclein seeds in CSF and tissue samples, including the olfactory mucosa in different patients' cohorts including Parkinson's patientients, patients with REM sleep behavior disorder (RBD), and patients with dementia with Lewy bodies.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-time Quaking-Induced Conversion (RT-QuIC)
Description: RT-QuIC is increasingly used as diagnostic tools in synucleinopathies and has shown high sensitivity and specificity for the detection of α-synuclein seeds in CSF and tissue samples, including the olfactory mucosa in different patients' cohorts including Parkinson's patientients, patients with REM sleep behavior disorder (RBD), and patients with dementia with Lewy bodies.
Study: NCT06026904

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: transcutaneous auricular vagus nerve stimulation
Description: taVNS was developed as a non-invasive variant of VNS where the vagus nerve is stimulated through the skin of the auricle, which has become a promising avenue for research and, potentially, treatment of various disorders. Commonly, taVNS is applied via the ear targeting the auricular branch of the vagus nerve, where the stimulation elicits far-field potentials. In line with preclinical studies, acute taVNS enhances invigoration of effort and response inhibition capability.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: transcutaneous auricular vagus nerve stimulation
Description: taVNS was developed as a non-invasive variant of VNS where the vagus nerve is stimulated through the skin of the auricle, which has become a promising avenue for research and, potentially, treatment of various disorders. Commonly, taVNS is applied via the ear targeting the auricular branch of the vagus nerve, where the stimulation elicits far-field potentials. In line with preclinical studies, acute taVNS enhances invigoration of effort and response inhibition capability.
Study: NCT06287060

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: strawberry extract.
Description: strawberry has a whitening effect due to its content of ellagic and maleic acids. the presence of acidic components namely ascorbic acid may increase the surface energy by removing the surface debris, thereby allowing the citric and maleic acids to penetrate into tooth surface to remove the surface stains.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strawberry extract.
Description: strawberry has a whitening effect due to its content of ellagic and maleic acids. the presence of acidic components namely ascorbic acid may increase the surface energy by removing the surface debris, thereby allowing the citric and maleic acids to penetrate into tooth surface to remove the surface stains.
Study: NCT06026891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MG-K10/Placebo
Description: MG-K10 Humanized Monoclonal Antibody Injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: MG-K10/Placebo
Description: MG-K10 Humanized Monoclonal Antibody Injection
Study: NCT05728164

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cinematic Simulation
Description: Comprehensive videos from specific films will be selected as films fitting the needs of participants and the established objectives. The films comprehensively develops several characters enriching the values of positive emotions, resilience and empathy. The intervention film videos will be delivered on 5 sessions for each group (2 sessions per week).
Study: NCT04869735

Intervention type: OTHER
Intervention: Data collection: DTPolio vaccine delivery
Description: with information about booster vaccination group: Sending of information concerning booster vaccination against DTPolio at 25 years using letters, emails and SMS without information about booster vaccination group: no intervention

Intervention type: OTHER
Intervention: Data collection: DTPolio vaccine delivery
Description: with information about booster vaccination group: Sending of information concerning booster vaccination against DTPolio at 25 years using letters, emails and SMS without information about booster vaccination group: no intervention
Study: NCT06178874

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin Glargine
Description: hyperglycemic control

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin Degludec
Description: hyperglycemic control

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin regular
Description: hyperglycemic control

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin regular
Description: hyperglycemic control

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin regular
Description: hyperglycemic control
Study: NCT04917094

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Compression stocking
Description: A below-the-knee compression stock will be worn daily for 2 weeks from waking up to before sleep.~Bioelectrical impedance will be performed before and 2 weeks after wearing the stocking to assess the total body water content.~Measuring the calf and neck circumference will be done before and after wearing the compression stocking. After 2 weeks, the patient will return back to the clinic for calf and neck circumference measurement.~Sleep test will be done the night before and 2 weeks after wearing the compression stocking. Oxygen Desaturation Index(ODI) will be assessed through a level 4 home sleep apnea testing device.~Patients recruited will have mild excessive to severe excessive daytime sleepiness and/or STOP-Bang score of 3 or more, with underlying conditions such as type II diabetes and hypertensive patients using the Epworth sleepiness scale. Epworth sleepiness scale will be assessed again 2 weeks after to assess for increase sleep efficiency.
Study: NCT06114862

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stigma-reduction intervention
Description: Participants will be presented with a list of common reasons why people report not wanting to tell other people about their mental health concerns, drawing from research in this area. Participants will be asked to click on any reason that resonates with them or about which they are interested in learning more. When they click on a particular reason, they will then be presented with psychoeducational information to allay their concerns. For example, if a participant replies that they wouldn't reach out to peers because others don't understand what I'm going through, we might present context showing that many of their peers have had similar challenges with mental health and have found peer support helpful. Participants will be able to click on as many reasons on this list that they would like to.
Study: NCT05897177

Intervention type: BEHAVIORAL
Intervention: Subjective Scale of Stigma and Discrimination (SISD).
Description: Subjective Scale of Stigma and Discrimination (SISD) A sixdimension self-administered scale will be used that included statements with which the participants agreed or disagreed. The scale consists of 23 Likert-type items and responses range from 1 (completely in disagreement) to 5 (completely in agreement), grouped together to represent the six indicators making up this part of the scale

Intervention type: BEHAVIORAL
Intervention: Subjective Scale of Stigma and Discrimination (SISD).
Description: Subjective Scale of Stigma and Discrimination (SISD) A sixdimension self-administered scale will be used that included statements with which the participants agreed or disagreed. The scale consists of 23 Likert-type items and responses range from 1 (completely in disagreement) to 5 (completely in agreement), grouped together to represent the six indicators making up this part of the scale
Study: NCT05192837

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive preoperative smoking cessation counselling
Description: The study intervention consists of an interview by a Tabacco Treatment Specialist (TSS) 4 weeks before surgery with individual counselling and offered nicotine substitution. The intervention meeting is based on the Chronic Care Model (CCM) to improve quality of ambulatory care.~In brief, the intervention includes:~* Informative content about advantages of smoking cessation~* Scheduling service for a motivational interview by a TSS in office to implement a treatment plan~* For participants willing to quit smoking a preoperative quit day will be scheduled after the first intervention meeting 2-3 weeks before surgery~* Patients will be encouraged by a TSS to use nicotine replacement. Bupropion or Vareniclin will be provided on an individual basis~* TSS will schedule repeated follow-up meetings to support smoking abstinence or nicotine reduction before and after surgery for all patients
Study: NCT06388551

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY03017
Description: single dose, administered orally

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: LY03017-Placebo
Description: single dose, administered orally
Study: NCT05907135

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beet
Description: Beet-based powder with other ingredients

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo powder.
Study: NCT06131515

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: extra corporeal shock wave therapy device
Description: Patients were seated in a relaxed position with their forearm and finger placed on the table. The median nerve was identified at the pisiform level of the proximal carpal tunnel, with the palm facing upwards. rESWT was delivered with the Physio Shock Wave Therapy system .The rESWT probe was located and oriented perpendicularly on the median nerve, and treatment comprised graduated shots at a bar pressure of 4 and a pulse repetition frequency of 5Hz for each patient ( The treated area was parallel to the median nerve from the pisiform level to 2 cm proximal to the inlet of the carpal tunnel with equal diffusion of 800, 900, 1000, 1100 shots from first to fourth session respectively. The procedure was painless, and there was no need for additional anesthesia or analgesia.~In the control group, sham rESWT just made the same sound without energy emission

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: extra corporeal shock wave therapy device
Description: Patients were seated in a relaxed position with their forearm and finger placed on the table. The median nerve was identified at the pisiform level of the proximal carpal tunnel, with the palm facing upwards. rESWT was delivered with the Physio Shock Wave Therapy system .The rESWT probe was located and oriented perpendicularly on the median nerve, and treatment comprised graduated shots at a bar pressure of 4 and a pulse repetition frequency of 5Hz for each patient ( The treated area was parallel to the median nerve from the pisiform level to 2 cm proximal to the inlet of the carpal tunnel with equal diffusion of 800, 900, 1000, 1100 shots from first to fourth session respectively. The procedure was painless, and there was no need for additional anesthesia or analgesia.~In the control group, sham rESWT just made the same sound without energy emission
Study: NCT05814120

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BLS training program
Description: BLS training program was in accordance with the 2020 AHA cardiopulmonary resuscitation (CPR) guidelines. The BLS training program adopts 4D teaching techniques, namely description (Describe), demonstration (Demo), implementation (Do), feedback (Debriefing).
Study: NCT05704946

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: THE EFFECT OF LAVENDER INHALATION ON SLEEP QUALITY IN INDIVIDUALS WITH CORONARY HEART DISEASE
Description: The index includes 24 questions that evaluate the quality of sleep and the type and severity of sleep disorders experienced in the last 1 month period. The total score in the index takes a value between 0-21. If the total score is higher than 5, it is interpreted as poor sleep quality.
Study: NCT05206279

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ureteral injection of Indocyanine Green Powder (diluted)
Description: The intervention we study is the intraureteral injection of ICG during a laparoscopic deep infiltrative endometriosis resection procedure. Cystoscopy with intraureteral administration of ICG will be performed, after which intervention the ureters will be examined by laparoscopy. ICG is injected cystoscopy-guided into the ureters (cystoscopy-guided) in a dosage of 5 or 10ml (25mg ICG in 5 or 10ml NaCl) per ureter as a bolus injection.
Study: NCT06174922

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone
Description: Prednisolone for 4 months

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone
Description: Prednisolone for 4 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Itraconazole
Description: SUBA-itraconazole for 4 months

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: SUBA-itraconazole for 4 months
Study: NCT02614352

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin + Candesartan

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin + Candesartan

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AG1502

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: AG1502
Study: NCT05216367

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquintinib will be administered as a single oral dose on the morning of day 1 under fasting conditions

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquintinib will be administered as a single oral dose on the morning of day 1 under fasting conditions

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquintinib will be administered as a single oral dose on the morning of day 1 under fasting conditions
Study: NCT06568835

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: exercise
Description: such as walking, jogging, swimming, Tai Chi, etc. It needs to be at a certain frequency and intensity
Study: NCT05244109

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Blood samples (2 times; 21mL per visit)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Blood samples (2 times; 21mL per visit)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: Blood samples (2 times; 21mL per visit)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: anti-TNF antibody administration
Description: Anti-TNF antibody administration, according to current recommendations and randomization results

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: anti-IL-17 antibody administration
Description: Anti-IL-17 antibody administration, according to current recommendations and randomization results
Study: NCT05349760

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AMB-05X
Description: A fully human monoclonal immunoglobulin (IgG2) directed against c-fms

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline/D5W
Study: NCT05572944

Intervention type: OTHER
Intervention: LDCT lung cancer screen, immediately
Description: Participants will receive the following things in sequence~1. Non-smoker lung cancer prediction model among Taiwanese population by questionnaire~2. Check autoantibodies against p53, NY-ESO-1, CAGE, GBU4-5, HuD, MAGE A4 and SOX2 in the blood of recruited patients and detect 133 SNPs and 11 mitochondrial mutations which are highly correlated with never-smoking lung cancer in our preliminary data~3. Check total bilirubin, urinary heavy metals, serum tumor marker, including CEA, alpha-fetal protein, etc.~4. Check pulmonary function test and chest X ray~5. Arrenge chest CT right away, and detection, classification, prediction of lung cancer risk in CT using deep learning and radiomics~6. Optimization and validation of lung cancer risk and probability prediction model: prospective multicenter clinical study.

Intervention type: OTHER
Intervention: LDCT lung cancer screen, later
Description: Participants will receive the following things in sequence~1. Non-smoker lung cancer prediction model among Taiwanese population by questionnaire~2. Check autoantibodies against p53, NY-ESO-1, CAGE, GBU4-5, HuD, MAGE A4 and SOX2 in the blood of recruited patients and detect 133 SNPs and 11 mitochondrial mutations which are highly correlated with never-smoking lung cancer in our preliminary data~3. Check total bilirubin, urinary heavy metals, serum tumor marker, including CEA, alpha-fetal protein, etc.~4. Check pulmonary function test.~5. Arrange AI-asisted chest X-ray right away.~6. Arrange chest CT three years later, and detection, classification, prediction of lung cancer risk in CT using deep learning and radiomics~7. Optimization and validation of lung cancer risk and probability prediction model: prospective multicenter clinical study.
Study: NCT06568276

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Additional deep deltoid ligament suture
Description: The deep deltoid ligament will be sutured through a curved incision lifting the tibialis posterior tendon out to be sutured back after tying the ligament to an anchor in the talus.
Study: NCT05466396

Intervention type: BEHAVIORAL
Intervention: smoking
Description: Smoking history and spirometry are used to define groups

Intervention type: BEHAVIORAL
Intervention: smoking
Description: Smoking history and spirometry are used to define groups
Study: NCT05818371

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Sonographic determination of the optic nerve sheath diameter
Description: Ultrasound-based determination of the optic nerve sheath diameter