TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05780619

Intervention type: DIAGNOSTIC_TEST
Intervention: Transcranial Doppler
Description: Measurement of resistance index on the middle cerebral artery (MCA) (index test) and the Holter (reference test). Patients will be randomized for order of tests

Intervention type: DIAGNOSTIC_TEST
Intervention: Transcranial Doppler
Description: Measurement of resistance index on the middle cerebral artery (MCA) (index test) and the Holter (reference test). Patients will be randomized for order of tests
Study: NCT06460207

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI neurofeedback
Description: fMRI neurofeedback is a technique that allows individuals to observe real-time feedback of their brain activity as measured by fMRI scans. During a session, the participant lies inside an MRI scanner while their whole brain is scanned. This data is processed in real-time by a computer and then presented to the participant in the form of visual feedback. This feedback might be presented as a graph, a color-coded representation, or some other easily interpretable format. The participant is instructed to modulate their brain activity based on the feedback they receive. This can involve various mental strategies, such as focusing attention on specific thoughts, images, or sensations. Over repeated sessions, participants learn to consciously influence their brain activity based on the feedback they receive. Through trial and error, they discover which mental strategies are most effective for achieving their desired changes in brain activity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI neurofeedback
Description: fMRI neurofeedback is a technique that allows individuals to observe real-time feedback of their brain activity as measured by fMRI scans. During a session, the participant lies inside an MRI scanner while their whole brain is scanned. This data is processed in real-time by a computer and then presented to the participant in the form of visual feedback. This feedback might be presented as a graph, a color-coded representation, or some other easily interpretable format. The participant is instructed to modulate their brain activity based on the feedback they receive. This can involve various mental strategies, such as focusing attention on specific thoughts, images, or sensations. Over repeated sessions, participants learn to consciously influence their brain activity based on the feedback they receive. Through trial and error, they discover which mental strategies are most effective for achieving their desired changes in brain activity.
Study: NCT06380868

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intravascular imaging-guided PCI
Description: Intravascular imaging including intravascular ultrasound or optical coherence tomography.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Angiography-guided PCI group
Description: Deployment of a drug-eluting stent under angiography.
Study: NCT06495489

Intervention type: OTHER
Intervention: Detection of preload responders by a PLR test
Description: Detection of preload dependency by using PLR test and echocardiography
Study: NCT05249374

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Recombinant Human Serum Albumin
Description: 10 g/bottle (20%, 50 mL)
Study: NCT05260398

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mightier Online Gameplay
Description: Mightier is a video-game-based biofeedback intervention that capitalizes on children's love of video games to increase emotional awareness and facilitate emotion regulation practice through heart rate (HR) control. Each family receives a Mightier Kit (Mighty Band heart rate monitor, dedicated Mightier tablet unless the family prefers to use their own device) and the Mightier App. Children wear a Mighty Band heart rate monitor on their arm while they play any one of 26+ games. As their heart rate rises the games become more difficult. For example, during a cooking game, smoke may appear on the screen and obscure the player's view. Children can either opt into an explicit cool down activity (deep breathing, progressive muscle relaxation, crossing the midline, or visualization) or cool down on their own. By simply playing Mightier, children are motivated to practice calming strategies in moments of challenge.
Study: NCT06020352

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN046 plus Axitinib
Description: KN046 combined with axitinib as a neoadjuvant treatment regimen
Study: NCT05564754

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feedback-controlled temperature device
Description: If core body temperature exceeds 37.7°C a feedback controlled-device will be used and set at 37.5°C.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feedback-controlled temperature device
Description: If core body temperature exceeds 37.7°C a feedback controlled-device will be used and set at 37.5°C.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feedback-controlled temperature device
Description: If core body temperature exceeds 37.7°C a feedback controlled-device will be used and set at 37.5°C.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Feedback-controlled temperature device
Description: If core body temperature exceeds 37.7°C a feedback controlled-device will be used and set at 37.5°C.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A MAP target of \>85mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A MAP target of \>85mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A MAP target of \>85mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High MAP
Description: A MAP target of \>85mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36h
Study: NCT05249374

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human serum albumin
Description: 10 g/bottle (20%, 50 mL)
Study: NCT05559138

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT05013684

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Particle Repositioning Maneuver
Description: treatment with Particle Repositioning Maneuver
Study: NCT06136793

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HomeStyles-China
Description: 2-arm \~10 week educational intervention

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HomeStyles-China
Description: 2-arm \~10 week educational intervention
Study: NCT05564754

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36h

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36h

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep sedation
Description: Deep sedation for at least 36h

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the ICU without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the ICU without a device
Study: NCT04717765

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Preventive, LLL Phototherapy and topical Vit E
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Preventive, LLL Phototherapy and topical Vit E
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Curative, LLL Phototherapy and topical Vit E
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Curative, LLL Phototherapy and topical Vit E
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Preventive, LLL Phototherapy and LPRF
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Preventive, LLL Phototherapy and LPRF
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Curative, LLL Phototherapy and LPRF
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Curative, LLL Phototherapy and LPRF
Description: Interventions will be carried out for patients who have already passed or will undergo anti-neoplastic chemotherapy or radiation therapy.
Study: NCT05288712

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training protocol with the device cervical for treatment (CDAT)
Description: Training protocol with the cervical device for treatment (CDAT)
Study: NCT06515678

Intervention type: DRUG
Intervention: arm A - angiotensin converting enzyme inhibitors (ACEi)
Description: Patients with ACEi monotherapy before or within 6 months following debulking surgery.~ACEi will be defined as any drugs from the Anatomical Therapeutic Classification C09AA with an indication for hypertension, including but not limited to: captopril, enalapril, lisinopril, perindopril, ramipril, quinapril

Intervention type: DRUG
Intervention: arm A - angiotensin converting enzyme inhibitors (ACEi)
Description: Patients with ACEi monotherapy before or within 6 months following debulking surgery.~ACEi will be defined as any drugs from the Anatomical Therapeutic Classification C09AA with an indication for hypertension, including but not limited to: captopril, enalapril, lisinopril, perindopril, ramipril, quinapril

Intervention type: DRUG
Intervention: arm A - angiotensin converting enzyme inhibitors (ACEi)
Description: Patients with ACEi monotherapy before or within 6 months following debulking surgery.~ACEi will be defined as any drugs from the Anatomical Therapeutic Classification C09AA with an indication for hypertension, including but not limited to: captopril, enalapril, lisinopril, perindopril, ramipril, quinapril

Intervention type: DRUG
Intervention: arm B - calcium channel blockers (CCBs)
Description: Patients with CCB monotherapy before or within 6 months following debulking surgery.~CCBs will be defined as any drugs from the Anatomical Therapeutic Classification C08CA with an indication for hypertension, including but not limited to: amlodipine, felodipine, isradipine, nicardipine, nifedipine

Intervention type: DRUG
Intervention: arm B - calcium channel blockers (CCBs)
Description: Patients with CCB monotherapy before or within 6 months following debulking surgery.~CCBs will be defined as any drugs from the Anatomical Therapeutic Classification C08CA with an indication for hypertension, including but not limited to: amlodipine, felodipine, isradipine, nicardipine, nifedipine

Intervention type: DRUG
Intervention: arm B - calcium channel blockers (CCBs)
Description: Patients with CCB monotherapy before or within 6 months following debulking surgery.~CCBs will be defined as any drugs from the Anatomical Therapeutic Classification C08CA with an indication for hypertension, including but not limited to: amlodipine, felodipine, isradipine, nicardipine, nifedipine

Intervention type: DRUG
Intervention: arm R - angiotensin receptor blockers ARB
Description: Patients with angiotensin receptor blocker (ARB) before or within 6 months following debulking surgery.~ARBs will be defined as any drugs from the Anatomical Therapeutic Classification C09CA with an indication for hypertension, including but not limited to: losartan, valsartan, irbesartan, candesartan or olmesartan medoxomil.
Study: NCT05564754

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the ICU without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fever control without a device
Description: Management of fever in the ICU without a device

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A MAP target of \>65mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A MAP target of \>65mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A MAP target of \>65mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low MAP
Description: A MAP target of \>65mmHg will be used. Vasopressors will be titrated to this target during 36h.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the ICU, used only as needed to facilitate transport, imaging and invasive procedures.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the ICU, used only as needed to facilitate transport, imaging and invasive procedures.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the ICU, used only as needed to facilitate transport, imaging and invasive procedures.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Minimal sedation
Description: A strategy of minimal sedation in the ICU, used only as needed to facilitate transport, imaging and invasive procedures.
Study: NCT05756894

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neurostimulation
Description: Paired stimulation will be given to the spinal cord and to peripheral nerves so that the signals are received at the spinal cord at a specific interval.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Repiratory training
Description: Respiratory exercises will be completed immediately after completing neurostimulation. Respiratory exercises will involve inspiratory muscle training performing four sets of 6-10 breaths per day with two minutes of rest.
Study: NCT05767645

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mistral Procedure
Description: The Mistral is an investigational device intended for percutaneous trans-catheter repair in high risk for surgery individuals suffering from functional Tricuspid Regurgitation (TR).~The device system is to be used only in accordance with the approved Investigational Plan on subjects who have signed an informed consent form. Device use is limited to the approved study investigators.
Study: NCT05265936

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Passing a guidewire through a double j stent
Description: The previously placed double J stent is removed up to the urethral meatus with a cystoscope and forceps and kept fixed at the meatal level without further pulling. Then, after reaching the kidney by passing a guidewire through it, the double j stent is removed. Followed by the routine lithotripsy procedure.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Double J stent removal and guidewire insertion
Description: The double j stent is completely removed with the cystoscope and forceps, and the guidwire is inserted into the ureter by visualizing it with the cystoscope. Followed by the routine lithotripsy procedure.
Study: NCT05956262

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AR-toothbrush machine
Description: Student in AR group received a two-time repeated AR-based training for 30 minutes at two-week intervals. The AR-based training system (PVIX Oral, EPED) digitized the steps of the toothbrushing technique applying optical tracking technology to enable the participants to obtain immediate scoring after the completion of practice. The scoring depends on the level of removing simulated dental plaque. The AR system was equipped with an optical tracking unit, a 3D training head model, and a wireless toothbrush. The toothbrushing practice time for the upper and lower jaw is 3 minutes, respectively. A tooth-brushing song played while the students implemented.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Teach proper brushing skills
Description: Students in the traditional group received a two-time repeated 10-minute lesson regarding proper toothbrushing skills in the classroom at two-week intervals. The students were taught by a well-trained dental hygienist using teaching aids (such as dental models, and toothbrushes).
Study: NCT05094570

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab Prefilled Syringe
Description: Dupilumab 300 mg
Study: NCT05711719

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vericiguat
Description: Up-titration will be performed as guided by the evaluation of blood pressure and clinical symptoms
Study: NCT05038436

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Polyglucosamine L112
Description: Two tablets once daily per os

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polyglucosamine L112
Description: Two tablets once daily per os
Study: NCT05475795

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Metapex
Description: obturation of root canals of primary molars with Metapex

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Metapex
Description: obturation of root canals of primary molars with Metapex

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Endoflas
Description: obturation of root canals of primary molars with Endoflas

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Endoflas
Description: obturation of root canals of primary molars with Endoflas
Study: NCT06505434

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Phaco + IOL Implantation

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Phaco + IOL Implantation

Intervention type: PROCEDURE
Intervention: Cataract surgery
Description: Phaco + IOL Implantation
Study: NCT05378204

Intervention type: OTHER
Group type: OTHER
Intervention: Main study:
Description: For each included patient, tumor biopsy specimen and blood samples will be collected at baseline visit (before the first dose of PARPi treatment).~During the treatment period: blood samples will be scheduled every 8 weeks (i.e. 2 cycles).~At the time of progression: tumor biopsy and blood samples will be collected.

Intervention type: OTHER
Group type: OTHER
Intervention: Sub-study:
Description: For each included patient, tumor biopsy specimen and blood samples will be collected as soon as possible after progression (before initiation of the post PARPi anti-tumoral treatment).
Study: NCT05677581

Intervention type: OTHER
Intervention: iodine nutrition status
Description: iodine nutrition status

Intervention type: OTHER
Intervention: iodine nutrition status
Description: iodine nutrition status
Study: NCT05711719

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered the same way
Study: NCT05165901

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Scrambler Therapy
Description: LG Medipain is a type of non-invasive neuromodulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Scrambler Therapy
Description: LG Medipain is a type of non-invasive neuromodulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Scrambler Therapy
Description: LG Medipain is a type of non-invasive neuromodulation.
Study: NCT05655962

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STARS
Description: STARS is a structured framework for assessment of rehabilitation and sicklisting, applied by primarily the rehabilitation coordinators working at the primary health care centers.
Study: NCT04813198

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: TIPSTART
Description: TIPSTART is a multimodal, cognitive behavior-based therapy integrating peer-sharing, technology, aerobic and resistance training.
Study: NCT05052762

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group A: Elastic resisted training for Gluteus Maximus strength
Description: Subjects attended physical therapy two times per week for a total of 10 visits. In the first five sessions, subjects performed the following exercises to strengthen the gluteus maximus: bilateral bridge, unilateral bridge, and non-weight-bearing hip extension in prone with the knee flexed at 90 degrees. In the next five sessions, abduction and external rotation in a quadruped (fire hydrant exercise) and weight-bearing hip extension (known as deadlift exercise) are added. Each exercise was performed for 10 repetitions. Elastic resistance was Added to the fire hydrant, hip extension in prone and deadlift exercises to allow each subject to perform at a 10-repetition maximum. The resistance for each subject was adjusted weekly as needed. The exercise program was performed under direct supervision only during the physical therapy sessions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group B: Weight resisted training for Gluteus Maximus strength
Description: Subjects attended p two times per week for a total of 10 visits. The participants performed PHEKF in 90° knee flexion with 30° hip abduction and 10° hip extension to increase the muscle activity of the gluteus maximus. In the prone position, the participant performed 10° hip extension until the posterior knee reached the horizontal bar. The participants maintained 90° knee flexion with 30° hip abduction and 10° hip extension in the prone position against the resistance. Sandbags (3 kg) will be used to provide resistance on the ankle through a rope and pulley. Each subject performed three sets with three repetitions of five seconds each. 1-minute break is allowed between each set.
Study: NCT05148598

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ADRCs
Description: Adipose Derived Regenerative Cells (ADRCs) processed with Celution System

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Care
Description: Standard care

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard Care
Description: Standard care

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo visually indistinguishable from ADRCs
Study: NCT05907772

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention