TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05512312

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Esthetic crown lengthening
Description: Conventional Surgical Esthetic Crown Lengthening

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computer guided Esthetic crown lengthening
Description: Computer guided Esthetic crown lengthening
Study: NCT01233570

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Once daily application for 12 weeks followed by 4 weeks observation. Optional 36 week open label extension
Study: NCT05491876

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest physiotherapy with breathing exercises and ACBT
Description: Group A got chest physiotherapy with breathing exercises and ACBT
Study: NCT05559905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Molnupiravir
Description: Four molnupiravir 200 mg capsules (800 mg total dose) taken twice daily by mouth.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Molnupiravir
Description: Four molnupiravir 200 mg capsules (800 mg total dose) taken twice daily by mouth.
Study: NCT05491876

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest physiotherapy with breathing exercises
Description: Group B got chest physiotherapy with breathing exercises.
Study: NCT05559905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo capsule matched to molnupiravir taken twice daily by mouth.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo capsule matched to molnupiravir taken twice daily by mouth.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsule matched to molnupiravir taken twice daily by mouth.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV A Memphis 37b
Description: RSV A Memphis 37b viral challenge given once by intranasal administration at a dosage of \~4 Log10 plaque forming units (PFUs).

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV A Memphis 37b
Description: RSV A Memphis 37b viral challenge given once by intranasal administration at a dosage of \~4 Log10 plaque forming units (PFUs).

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: RSV A Memphis 37b
Description: RSV A Memphis 37b viral challenge given once by intranasal administration at a dosage of \~4 Log10 plaque forming units (PFUs).
Study: NCT04960748

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WOMEN FIGHTING TO STOP CERVICAL CANCER
Description: The group intervention draws on theories of social diffusion, cognitive consistency, and social influence, and our own recently developed and tested group intervention that mobilized people living with HIV in Uganda to successfully act as change agents for HIV prevention within their social networks. The intervention actively targets internalized stigma, disclosure decision making, healthy living, and advocacy communication skills. The ultimate goal of the program is to encourage female social network members to get screened for cervical cancer.
Study: NCT04923633

Intervention type: DEVICE
Intervention: Quantifiable Soft Tissue Manipulation (QSTM)
Description: Quantifiable soft tissue manipulation (QSTM) is a force sensing device system that can be used by a clinician to apply a massaging force while the system monitors objective metrics, i.e., the amount, rate, and angle of force applied.
Study: NCT06035536

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Symphony™ plus Off-loading
Description: Application of Symphony™

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Wound Dressing comprising of calcium alginate Fibracol
Description: Application of Wound Dressing comprising of calcium alginate Fibracol.
Study: NCT06248463

Intervention type: DIAGNOSTIC_TEST
Intervention: BP measurement in waiting room for 20 minutes
Description: Measured of BP will be performance in waiting room for 20 minutes every 3 minutes and report by an mobile app. After 24h-ABPM device will be implanted. Results of SBP and DBP obtained in office will be compared with 24-h, diurnal and nocturnal SBP/DBP mean.~BP will be measured automatically and repeatedly every 3 minutes in the waiting room for 20 minutes. Subsequently, a SpaceLab ABPM monitor will be implanted.
Study: NCT04503772

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Preoperative SRS
Description: Patient will be treat with preoperative SRS and then surgery for brain metastases is realized within 3 days.
Study: NCT05939271

Intervention type: PROCEDURE
Intervention: lower extremity amputation
Description: persons are defined as having a lower extremity amputation when an operation with removal of an extremity below the hips took place.~To identify those people with diabetes who underwent amputation, the following DBC's claims were extracted from the system: 038590; amputation upper leg, 038690; amputation lower leg, 038691; exarticulation of the lower leg, 038790; amputation of the tarsus, 038791; amputation or exarticulation of a toe, 038793; exarticulation of the foot, 038794; Chopart exarticulation, Lisfranc, respectively trans metatarsal amputation. Amputations were categorized into minor (038790, 038791, 038793, 038794) and major (038590, 038690,038691) amputations

Intervention type: PROCEDURE
Intervention: lower extremity amputation
Description: persons are defined as having a lower extremity amputation when an operation with removal of an extremity below the hips took place.~To identify those people with diabetes who underwent amputation, the following DBC's claims were extracted from the system: 038590; amputation upper leg, 038690; amputation lower leg, 038691; exarticulation of the lower leg, 038790; amputation of the tarsus, 038791; amputation or exarticulation of a toe, 038793; exarticulation of the foot, 038794; Chopart exarticulation, Lisfranc, respectively trans metatarsal amputation. Amputations were categorized into minor (038790, 038791, 038793, 038794) and major (038590, 038690,038691) amputations
Study: NCT05621018

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Maze Out
Description: Play for 15 weeks, at list once a week the serious game: Maze Out

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Maze Out
Description: Play for 15 weeks, at list once a week the serious game: Maze Out
Study: NCT06266572

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Overcoming and Addressing Stigma in Substance Use Disorders (OASIS)
Description: Web-based educational platform for clinicians and individuals with OUD that will decrease barriers to care and enhance treatment outcomes

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Overcoming and Addressing Stigma in Substance Use Disorders (OASIS)
Description: Web-based educational platform for clinicians and individuals with OUD that will decrease barriers to care and enhance treatment outcomes
Study: NCT06497621

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single step PVS impression
Description: Single-step final impression method for complete denture fabrication using medium body PVS for border molding and wash impression in a single-step (i.e., one insertion of impression tray in mouth).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional two-step PVS impression
Description: Border molding with heavy-body PVS first, followed by wash impression with light-body PVS
Study: NCT06025084

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Egg Shell nanoparticles
Description: Evaluate the effects of egg shell nanoparticles combined with Titanium dioxide nanoparticles in the treatment of dentin hypersensitivity at different time intervals.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Egg Shell nanoparticles
Description: Evaluate the effects of egg shell nanoparticles combined with Titanium dioxide nanoparticles in the treatment of dentin hypersensitivity at different time intervals.
Study: NCT04933409

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 3D printed replica of the donor tooth
Description: 3D printed replica of the donor tooth.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Autotransplantation of tooth
Description: Conventional Autotransplantation of tooth without using the 3D printed guide
Study: NCT06162871

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Presentations and interactive debate sessions, with intergenerational exchange
Description: Intervention will consist of 12 sessions, each lasting about two hours, conducted on a weekly basis and delivered both in-person and remotely. The sessions will include presentations and interactive debate sessions, with a central focus on intergenerational exchange covering cultural, historical, and health-related topics. A key aspect is the active involvement of beneficiaries, individuals over sixty-five, who will be asked to prepare presentations with the support of project-provided facilitators. Simultaneously, the project will promote and enhance skills, organizational capabilities, and computer literacy.
Study: NCT05615038

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Contact aspiration Thrombectomy
Description: Contant aspiration is an approach that utilizes the advantages of large-bore aspiration catheters that can be easily tracked and introduced into the cerebral circulation to directly remove the thrombus via negative pressure aspiration.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Stent retriever thrombectomy
Description: Stent retriever thrombetomy is an approach that utilize sself-expandable stent for thrombectomy. The stent retriever is expanded to capture the thrombus, which immediately may restore blood flow.
Study: NCT05578196

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fecal bacteria solution
Description: The gastrointestinal tube access was established, and the standard preparation of fecal bacteria solution 20ml (frozen at -80 ° C, melted at room temperature before use) was injected through the gastrointestinal tube once a day for 6 consecutive days. The other treatment measures were the same as those of the control group.

Intervention type: DRUG
Group type: OTHER
Intervention: physiological saline solution
Description: physiological saline solution 20ml
Study: NCT05223699

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MGTA-117
Description: MGTA-117 will be administered as an IV infusion
Study: NCT05057325

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulpectomy using single file system ( One Shape file)
Description: Rotary file instrument for pulpectomy of primary molars ( One shape file)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulpectomy using single file system ( WaveOne Gold file)
Description: Rotary file instrument for pulpectomy of primary molars ( WaveOne Gold file)
Study: NCT04290403

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pull Ups
Description: Participants will be asked to wear pull-ups continence products for the duration of four weeks

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Styled Briefs with tapes
Description: Participants will be asked to wear styled briefs with tapes for the duration of four weeks
Study: NCT05525039

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-magnitude High-frequency Vibration
Description: 0.3g, 35Hz, 20mins/day, at least 3 times/week

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Low-magnitude High-frequency Vibration
Description: 0.3g, 35Hz, 20mins/day, at least 3 times/week

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: β-hydroxy β-methylbutyrate (HMB) supplement
Description: Oral nutritional HMB supplement at 3g/day

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: β-hydroxy β-methylbutyrate (HMB) supplement
Description: Oral nutritional HMB supplement at 3g/day

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Protein supplement
Description: Daily protein supplement intake

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein supplement
Description: Daily protein supplement intake

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Protein supplement
Description: Daily protein supplement intake

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Protein supplement
Description: Daily protein supplement intake
Study: NCT05743127

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D-Printed Hyrax Expander
Description: This is a type of maxillary expander that is designed on a computer and printed in metal using 3D printers and is used to expand the upper jaw.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional Laboratory Fabricated Hyrax Expander
Description: This is a type of maxillary expander that is made by hand in an orthodontic laboratory and is used to expand the upper jaw.
Study: NCT04976790

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chinese Tuina therapy
Description: Firstly, the patient is in the prone position, and the doctor use the method of rolling or kneading the Bladder meridians on both sides of the spine. The waist will be focused on to manipulate preferentially and then using the same technique on the patient's back, buttocks and lower limbs. Secondly, the physician will perform the manipulation on the patient's waist and the posterolateral side of the lower limbs by pressing, kneading, plucking. The doctors press the acupoints, including Mingmen(DU04),Shenshu(BL23),Yaoyangguan(DU03),Huantiao(GB30), Weizhong(BL40),Chengshan(BL57),and Ashi points, with the elbow or the thumb to achieve Deqi sensation. Thirdly, the The doctor uses the method of pressing acupoints, including Tianshu(ST25),Qichong(ST30),Chongmen(SP12),Daimai(GB26),Jingmen(GB25) on both sides. Fourthly, the patient is required to face the doctor in a lateral position for pulling manipulation on the both sides of lumbar vertebrae.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Flurbiprofen Cataplasms group (FCG).
Description: One Flurbiprofen Cataplasm was applied to the left and right sides of the waist, twice daily, for 14 days
Study: NCT05710133

Intervention type: OTHER
Group type: OTHER
Intervention: food
Description: alectinib-d6 will be administered with breakfast on day 1 to determine the food-effect

Intervention type: OTHER
Group type: OTHER
Intervention: fast
Description: alectinib-d6 will be administered after an overnight fast of minimal 10 hours on day 9 to determine the food-effect
Study: NCT06527261

Intervention type: OTHER
Intervention: Real-time electronic data input into REDCap
Description: During usual care sessions, clinicians will real-time capture information about the intervention session into REDCap. This information is related to the multi-dimensional dose articulation framework e.g., content of the session and difficulty of the task, session length, episode length, and number of repetitions.~The usual care motor upper limb intervention the patient receives is determined by the clinician providing the care. The therapy may include but is not limited to strength training, task specific retraining, constraint induced movement therapy, mirror box, and electrical stimulation.

Intervention type: OTHER
Intervention: Real-time electronic data input into REDCap
Description: During usual care sessions, clinicians will real-time capture information about the intervention session into REDCap. This information is related to the multi-dimensional dose articulation framework e.g., content of the session and difficulty of the task, session length, episode length, and number of repetitions.~The usual care motor upper limb intervention the patient receives is determined by the clinician providing the care. The therapy may include but is not limited to strength training, task specific retraining, constraint induced movement therapy, mirror box, and electrical stimulation.
Study: NCT06368843

Intervention type: DRUG
Intervention: Gargle with ketamine
Description: The patients asked to gargling with ketamine solution in the preoperative waiting area after explain the whole procedure and the goals of the study.
Study: NCT06285565

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nurse-led telephone coaching intervention with home telemonitoring of vital signs
Description: In addition to standard care, the intervention group will receive a nurse-led supportive programme that involves a pre-discharge educational meeting and 6-month telephone coaching sessions. Patient's caregivers will also be invited to participate. After discharge, patients will be asked to measure their vital signs, daily. In case of alteration, the nurse will ascertain the presence of congestion symptoms and decide to reinforce the recommendations for self-management, request a specialist medical consultant, or refer to the emergency services
Study: NCT06140368

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: virtual reality
Description: During the trigger point injection, patients will be shown videos that the patient wants to watch, such as nature and seaside walks, underwater videos, with music background, through virtual reality glasses for 10 minutes.
Study: NCT05618210

Intervention type: OTHER
Intervention: regional anesthesia
Description: in the ESPB group, the linear ultrasound probe was placed in the erector spina muscles were visualized on the side where VATS was planned. block needle can be seen on ultrasound, the skin and erector spina muscles are passed in the cranio-caudal direction. ESPB will be administered with 20 ml of 0.5% bupivacaine by visualizing the local anesthetic spread linearly.~In the rhomboid intercostal block group, the ipsilateral arm is positioned towards the chest, allowing the scapula to move laterally and the area called auscultation triangle to be opened, and after the skin disinfection of the surgical side; By using a linear ultrasound probe, the rhomboid major and intercostal muscles will be defined in the auscultation triangle region, and T5-6 level with an in-plane approach with 20 ml of 0.5% bupivacaine and local anesthetic injection.

Intervention type: OTHER
Intervention: regional anesthesia
Description: in the ESPB group, the linear ultrasound probe was placed in the erector spina muscles were visualized on the side where VATS was planned. block needle can be seen on ultrasound, the skin and erector spina muscles are passed in the cranio-caudal direction. ESPB will be administered with 20 ml of 0.5% bupivacaine by visualizing the local anesthetic spread linearly.~In the rhomboid intercostal block group, the ipsilateral arm is positioned towards the chest, allowing the scapula to move laterally and the area called auscultation triangle to be opened, and after the skin disinfection of the surgical side; By using a linear ultrasound probe, the rhomboid major and intercostal muscles will be defined in the auscultation triangle region, and T5-6 level with an in-plane approach with 20 ml of 0.5% bupivacaine and local anesthetic injection.
Study: NCT05233488

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Ultrasound Therapy
Description: Ultrasound therapy is applied in the pulsed mode.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Ultrasound Therapy
Description: Ultrasound therapy is applied in the pulsed mode.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Ultrasound Therapy
Description: Ultrasound therapy is applied in the pulsed mode.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Ultrasound Therapy
Description: Ultrasound therapy is applied in the pulsed mode.
Study: NCT04841785

Intervention type: DIAGNOSTIC_TEST
Intervention: mailer-based finger-prick
Description: All participants in the antibody measurement study will be sent a mailer-based finger-prick set. The sets will be sent to the home address of the patient, including a return envelope. After collecting and returning the samples SARS-CoV-2 antibodies will be analysed quantitatively at the laboratory.

Intervention type: DIAGNOSTIC_TEST
Intervention: mailer-based finger-prick
Description: All participants in the antibody measurement study will be sent a mailer-based finger-prick set. The sets will be sent to the home address of the patient, including a return envelope. After collecting and returning the samples SARS-CoV-2 antibodies will be analysed quantitatively at the laboratory.

Intervention type: DIAGNOSTIC_TEST
Intervention: mailer-based finger-prick
Description: All participants in the antibody measurement study will be sent a mailer-based finger-prick set. The sets will be sent to the home address of the patient, including a return envelope. After collecting and returning the samples SARS-CoV-2 antibodies will be analysed quantitatively at the laboratory.
Study: NCT06471699

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continous Glucose Monitoring
Description: The aim is to examine if the use of CGM will give the participants a significant support to implement lifestyle improvements in individuals with new on-set type 2 diabetes

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self monitoring blood glucose
Description: Capillary testing as in standard procedure
Study: NCT05063617

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SCI Step Together
Description: The 8-week program features weekly blocks of content. Each week builds from the previous week and targets specific components related to the three basic psychological needs (autonomy, relatedness, competence). The overall cadence of each weekly block is maintained throughout. For example, each week contains: 1) education modules 2) a worksheet or guided practice to apply the strategies in their own goals for that week along with embedded questions to discuss with their community coach 3) behavioural support from the community coach and 4) peer support from the discussion group.
Study: NCT05979155

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NWY001
Description: Part 1: Participants will be given a single-dose of NWY001 intravenously once every 3 weeks until a discontinuation criteria was met during treatment period.
Study: NCT05644600

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nintedanib
Description: The subjects will be administered Nintedanib soft capsules single oral dose in the morning of Day 1 in fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nintedanib
Description: The subjects will be administered Nintedanib soft capsules single oral dose in the morning of Day 1 in fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nintedanib
Description: The subjects will be administered Nintedanib soft capsules single oral dose in the morning of Day 1 in fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5055
Description: The subjects will be administered AZD5055 as single oral dose on Day 1 in the fasted state.
Study: NCT05979155

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NWY001
Description: Part 2: Participants will be given RP2D of NWY001 intravenously once every 3 weeks until a discontinuation criteria was met during treatment period.