TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06729229

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator - Control lunch (no fish) and placebo supplement

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary Supplement/Vitamins
Description: Experimental - 2 portions of fish (280g) per week and omega 3 supplement
Study: NCT06728904

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi intervention
Description: 40-90 minutes per session, 3-5 sessions per week. 6. Each practice mainly includes basic theoretical knowledge, warm-up exercises, standing exercises, Chen style Tai Chi, and relaxation techniques. This study expects to divide the Tai Chi intervention program into three stages: the first stage is the introductory learning of simple high-intensity Chen style Tai Chi, the second stage is the combination of strength training and Chen style Tai Chi courses, and the third stage uses optional high-intensity competitive Chen style Tai Chi or Tai Chi Sword as advanced content to consolidate learning outcomes, such as the 32 style Tai Chi Sword (HR of about 120 times/minute). The intervention plan will be combined with high-intensity interval training (HIIT) to adapt Chen style Tai Chi.
Study: NCT06727786

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Serious game training
Description: A serious game featuring a dramatic/realistic film, pauses with questions for active learning, and practice administration of naloxone and performing CPR
Study: NCT06728566

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inmersive virtual reality
Description: In addition to conventional training, IVR training aims to provide a detailed preview of the tasks and procedures required in the standard training with selected virtual scenarios:~Scenario 1: Inspection and Use of Personal Protective Equipment (PPE):~In this scenario, the worker will inspect the equipment to ensure it is in good condition and properly used: Harness, Helmet, Lanyards, Carabiners, Lifelines, Energy Absorbers~Scenario 2: Working on an Elevated Metal Structure:~Structure Ascent: Ascent Method: Use specific ascent systems, ensuring you are always connected to an anchor point.~Positioning on the Structure: Secure Anchorage: Once the working position is reached, secure the anchor to a fixed and reliable point.~Structure Descent: Unanchoring and Reanchoring: Unanchor and re-anchor at secure points as you descend.~Additional Safety Measures: Weather Conditions, signage and delimitation:~Scenario 3: Rescue at Heights: Accessing the Person in Danger, rescue Techniques.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional training
Description: The working at heights training provided by the National Learning Service (SENA) in Colombia includes key steps to ensure safety and proper equipment use:~* Harness Use: Inspect for damage, wear it like a vest, and ensure correct orientation. Adjust shoulder and leg straps for comfort and secure the chest strap.~* Final Check: Verify D-rings are correctly positioned, and all buckles are securely fastened.~* Helmet: Inspect for damage and adjust for a secure fit.~* Lanyards: Select in good condition, connect properly, keep tension, and avoid overloading.~* Carabiners: Use certified carabiners with functioning locks, connected to proper points.~* Lifelines and Energy Absorbers: Install and tension lifelines properly; check energy absorbers before use.~* Climbing/Descending: Maintain three contact points and secure tools to avoid accidents.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional training
Description: The working at heights training provided by the National Learning Service (SENA) in Colombia includes key steps to ensure safety and proper equipment use:~* Harness Use: Inspect for damage, wear it like a vest, and ensure correct orientation. Adjust shoulder and leg straps for comfort and secure the chest strap.~* Final Check: Verify D-rings are correctly positioned, and all buckles are securely fastened.~* Helmet: Inspect for damage and adjust for a secure fit.~* Lanyards: Select in good condition, connect properly, keep tension, and avoid overloading.~* Carabiners: Use certified carabiners with functioning locks, connected to proper points.~* Lifelines and Energy Absorbers: Install and tension lifelines properly; check energy absorbers before use.~* Climbing/Descending: Maintain three contact points and secure tools to avoid accidents.
Study: NCT06471504

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Eyelink Portable Duo
Description: Eye-tracking data will be collected using a commercially-available remote eye-tracking system (Eyelink Portable Duo). Eye movements and pupil diameter will be collected while participants view a series of developmentally appropriate pictures and movies. The eye-tracker consists of two cameras; one that monitors eye movements and a second scene camera that monitors head movements, which permits eye tracking to take place without any equipment touching the child. Children will be asked to sit in highchair or on their caregiver's lap and will face a computer monitor. After a sticker is applied to the child's forehead and brief eye-movement calibration completed, next visual stimuli (i.e., pictures and videos) will be presented on a laptop computer monitor that is placed at approximately 60-80cm from the child. The eye tracking portion of the visit will last approximately 15 minutes or until the child is no longer able to attend to pictures/videos.
Study: NCT06199180

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: pulmonary vein isolation with RFA
Description: Patients randomised to RFA will undergo PVI with point-by-point RFA.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: pulmonary vein isolation with PFA
Description: Patients randomised to PFA will undergo PVI with PFA.
Study: NCT06316310

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: acupoint thread embedding
Description: Acupoint embedding therapy:Main acupoints: Shangguan (CV-13), Xiaguan (CV-10), Tianshu (ST-25), Daheng (SP-15), Fenglong (ST-40), Qihai (CV-6), Zhongguan (CV-12), Zusanli (ST-36), Quchi (LI-11), Guanyuan (CV-4), Wailing (ST-26), Daju (ST-27), Shuidao (ST-28), Daimai (GB-26), Liangmen (ST-21), Ashi acupoints , where local fat accumulation in the abdomen. Methods of operation: With the patient in the prone position and all acupoints routinely sterilized, the acupuncturist will use sterile forceps to insert a 3-0 × 2-cm poly-p-dimethyl-hydroxy-oxazolone (PDO) thread into the tip of the #6 (0.6 mm × 60 mm) disposable embedded thread needle. The tissue around the area of the acupuncture point will be lifted with the thumb and forefinger of the non-dominant hand and the needle will be inserted into the acupuncture point to a depth of 1.5 cm with the dominant hand. Each treatment will last maximum of 10 minutes and the intervention will be repeated every 2 weeks for a total of 6 sessions.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: acupoint thread embedding
Description: Acupoint embedding therapy:Main acupoints: Shangguan (CV-13), Xiaguan (CV-10), Tianshu (ST-25), Daheng (SP-15), Fenglong (ST-40), Qihai (CV-6), Zhongguan (CV-12), Zusanli (ST-36), Quchi (LI-11), Guanyuan (CV-4), Wailing (ST-26), Daju (ST-27), Shuidao (ST-28), Daimai (GB-26), Liangmen (ST-21), Ashi acupoints , where local fat accumulation in the abdomen. Methods of operation: With the patient in the prone position and all acupoints routinely sterilized, the acupuncturist will use sterile forceps to insert a 3-0 × 2-cm poly-p-dimethyl-hydroxy-oxazolone (PDO) thread into the tip of the #6 (0.6 mm × 60 mm) disposable embedded thread needle. The tissue around the area of the acupuncture point will be lifted with the thumb and forefinger of the non-dominant hand and the needle will be inserted into the acupuncture point to a depth of 1.5 cm with the dominant hand. Each treatment will last maximum of 10 minutes and the intervention will be repeated every 2 weeks for a total of 6 sessions.
Study: NCT06398158

Intervention type: DRUG
Intervention: Ravulizumab
Description: All study participants will receive commercially covered ravulizumab consistent with the indication, dose and frequency contained within the approved label.
Study: NCT06002711

Intervention type: DIAGNOSTIC_TEST
Intervention: MR scanning; Clinical data collection
Description: Multi-dimensional spatial heterogeneity analysis of MRI

Intervention type: DIAGNOSTIC_TEST
Intervention: MR scanning; Clinical data collection
Description: Multi-dimensional spatial heterogeneity analysis of MRI
Study: NCT06336018

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etavopivat
Description: Participants will receive a single dose of etavopivat orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etavopivat
Description: Participants will receive a single dose of etavopivat orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etavopivat
Description: Participants will receive a single dose of etavopivat orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etavopivat
Description: Participants will receive a single dose of etavopivat orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etavopivat
Description: Participants will receive a single dose of etavopivat orally.
Study: NCT06331637

Intervention type: PROCEDURE
Intervention: Transanal Transection and Single-Stapled anastomosis (TTSS)
Description: Restorative proctectomy with Transanal Transection and Single-Stapled (TTSS) Ileal Pouch-Anal Anastomosis (IPAA)

Intervention type: PROCEDURE
Intervention: Double-stapled anastomosis
Description: Restorative proctectomy with Tdouble-stapled Ileal Pouch-Anal Anastomosis (IPAA)
Study: NCT05180539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SPLASH Intervention Condition
Description: Two-session in person group discussions focusing on behaviors in drinking contexts

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control Condition
Description: Two-session in person group discussions focusing on college health behaviors
Study: NCT05604365

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: FearLess Intervention
Description: 8-12 weekly telehealth sessions one hour in length.The intervention includes psychotherapy techniques varying from relaxation response to self-regulation targeted to the specific fears of patients with glioma.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: FearLess Intervention
Description: 8-12 weekly telehealth sessions one hour in length.The intervention includes psychotherapy techniques varying from relaxation response to self-regulation targeted to the specific fears of patients with glioma.
Study: NCT05720637

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SSRI
Description: SSRIs antidepressants, including fluoxetine, paroxetine, sertraline, citalopram, etc., will be administered at oral doses determined by the psychiatrist. Once daily for the duration of the trial.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: SSRI
Description: SSRIs antidepressants, including fluoxetine, paroxetine, sertraline, citalopram, etc., will be administered at oral doses determined by the psychiatrist. Once daily for the duration of the trial.

Intervention type: DRUG
Group type: OTHER
Intervention: SSRI
Description: SSRIs antidepressants, including fluoxetine, paroxetine, sertraline, citalopram, etc., will be administered at oral doses determined by the psychiatrist. Once daily for the duration of the trial.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SIA
Description: This study will select 4 acupoints (all taken bilaterally) commonly used to treat MDD, namely Taichong (LR3), Neiguan (PC6), Sanyinjiao (SP6) and Shenmen (HT7). The SIA will use the same size, colour and material as the AIA with a thin silicone pad in the middle instead of the needle body. SIA will be attached to the acupoints and retained for 72 hours, removed and rested for one day. A total of 10 sessions will be performed over a period of 6 weeks.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AIA
Description: This study will select 4 acupoints (all taken bilaterally) commonly used to treat MDD, namely Taichong (LR3), Neiguan (PC6), Sanyinjiao (SP6) and Shenmen (HT7). Depending on acupoints' location, a φ0.20\*1.5mm or φ0.20\*1.2mm AIA will be selected. Press the AIA to insert it vertically into the acupoint and retain it in the skin. AIA will be retained for 72 hours with a day's rest after removal. During the period of needle retention, participants will be instructed to press the AIA 3-4 times a day for approximately 1 minute each time, with as much stimulation as the patient can tolerate, at intervals of approximately 4 hours. A total of 10 sessions will be performed over a period of 6 weeks.
Study: NCT04101292

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Characterization of tumor tissue by fluorescence
Description: * HSI Imaging of the resected specimen, from the serum and the mucous side~* FF-OCT imaging of the tumor and the healthy tissue biopsies~* Local application of Bevacizumab-IRDye800CW and visualization with the Surgvision Explorer system~* Standard anti-VEGF Immunohistochemistry and pathology
Study: NCT05334667

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine management
Description: Routine management

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Routine management
Description: Routine management

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine management
Description: Routine management

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CRRT
Description: Prisma-flex (Gambro-Swedan) machine will be used to carry out both CRRT and PPH sessions. Each CRRT session continue for 72 hours, while PPH session continue for 4 hours.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PPH
Description: Prisma-flex (Gambro-Swedan) machine will be used to carry out both CRRT and PPH sessions. Each CRRT session continue for 72 hours, while PPH session continue for 4 hours.
Study: NCT05968144

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dietary recommendations
Description: One-on-one meeting with a nutritionist to discuss and personalize dietary recommendations for patients with prostate cancer undergoing ADT.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dietary recommendations
Description: One-on-one meeting with a nutritionist to discuss and personalize dietary recommendations for patients with prostate cancer undergoing ADT.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time-restricted eating
Description: 12 weeks of time-restricted eating (10-hour window)
Study: NCT06446934

Intervention type: DEVICE
Group type: OTHER
Intervention: CPAP
Description: Initial CPAP titration and subsequent CPAP therapy for 12 weeks
Study: NCT04816916

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AXA1665
Description: AXA1665 administered TID with food

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo administered TID with food
Study: NCT06207409

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PARTS-SUD
Description: The Program for Alleviating and Reducing Trauma, Stress and Substance Use (PARTS-SUD) is a 12-week, Internal Family Systems-based, group intervention with 6 individual clinical sessions on a biweekly basis.
Study: NCT04682899

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: procalcitonin-guided antibiotic therapy
Description: In procalcitonin group, clinican make a decision of antibiotic precription based on the results of procalcitonin.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: guideline-guided antibiotic therapy
Description: In guideline group, clinican make a decision of antibiotic precription based on the recommendations of GOLD guideline.
Study: NCT05648903

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Total diet replacement
Description: The TDR intervention involves a low-calorie, nutritionally complete diet for 12 weeks consuming four meal replacement products exclusively per day, followed by a 4-week food-based reintroduction period; and then weight loss maintenance support monthly to 12 months. The TDR products will be provided to participants free of charge. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a TDR for an additional 4 weeks but participants would have to self-fund these products.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Total diet replacement
Description: The TDR intervention involves a low-calorie, nutritionally complete diet for 12 weeks consuming four meal replacement products exclusively per day, followed by a 4-week food-based reintroduction period; and then weight loss maintenance support monthly to 12 months. The TDR products will be provided to participants free of charge. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a TDR for an additional 4 weeks but participants would have to self-fund these products.
Study: NCT06224127

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active heat
Description: Users receive an active Soovu heating pod(s).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active heat
Description: Users receive an active Soovu heating pod(s).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Active c tactile fiber stimulation
Description: Hair brushes that activate c tactile fibers

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Active c tactile fiber stimulation
Description: Hair brushes that activate c tactile fibers

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: sham heat
Description: A Soovu heating pod(s) in the subtherapeutic temperature range

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sham c tactile fiber stimulation
Description: Hair brushes that do not activate c tactile fibers
Study: NCT05737862

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Moringa oleifera capsules
Description: In this arm, pregnant mothers receive capsules containing 500 mg of powdered Moringa oleifera leaves which contain 13.09 mg of iron per100 gram. Dose: 2 × 2 capsules per day for 30 days
Study: NCT05648903

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-carbohydrate diet
Description: Participants who choose this intervention will be supported to undertake a low-carbohydrate diet. During the first 12 weeks of the programme patients will be supported to consume below 100g carbohydrate per day, whilst being encouraged to increase protein, choose predominantly unsaturated fats alongside a high intake of non-starchy vegetables and low-carbohydrate fruits. After 12 weeks patients will be able to increase their carbohydrate intake up to 130g per day. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a 100g carbohydrate for an additional 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-carbohydrate diet
Description: Participants who choose this intervention will be supported to undertake a low-carbohydrate diet. During the first 12 weeks of the programme patients will be supported to consume below 100g carbohydrate per day, whilst being encouraged to increase protein, choose predominantly unsaturated fats alongside a high intake of non-starchy vegetables and low-carbohydrate fruits. After 12 weeks patients will be able to increase their carbohydrate intake up to 130g per day. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a 100g carbohydrate for an additional 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intermittent fasting 5:2
Description: Participants will have the option to follow a 5:2 dietary approach whereby calories are significantly reduced on two days of the week to 500 calories per day for women and 600 calories per day for men. The placement of the fasting days can vary each week, but there must be two fasting days in each seven-day period. After 12 weeks, patients will have the option of continuing with the 5:2 approach for further weight loss or adopting a 6:1 approach whereby patients would only fast on 1 day in each seven-day cycle for weight maintenance. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a 5:2 approach for an additional 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intermittent fasting 5:2
Description: Participants will have the option to follow a 5:2 dietary approach whereby calories are significantly reduced on two days of the week to 500 calories per day for women and 600 calories per day for men. The placement of the fasting days can vary each week, but there must be two fasting days in each seven-day period. After 12 weeks, patients will have the option of continuing with the 5:2 approach for further weight loss or adopting a 6:1 approach whereby patients would only fast on 1 day in each seven-day cycle for weight maintenance. If a patient gains more than 2kg in the maintenance phase, they have the option to follow a 5:2 approach for an additional 4 weeks.
Study: NCT04723459

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ivermectin impregnated mask
Description: mask with ivermectin nano solution