TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04852471

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Post-Operative Counseling + FACT-G
Description: Counseling at discharge + FACT-G at enrollment, at 15-18 and at 30-32 days post-operative.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Post-Operative Counseling + FACT-G
Description: Counseling at discharge + FACT-G at enrollment, at 15-18 and at 30-32 days post-operative.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PROM symptom tracker
Description: A 12-item symptom tracker adopted from the Patient Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (NCI-PRO-CTCAE), delivered via text, on days 4, 6, 8, 12, 18, 24, and 30 post surgery.
Study: NCT06041165

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JS401
Description: Single dose of JS401 by subcutaneous (sc) injections

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Calculated volume to match active treatment
Study: NCT04073472

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mesenchymal stem cells (MSCs)
Description: Allogeneic bone marrow derived mesenchymal stem cells (MSCs) direct injection to an ileal pouch fistula in the setting of Crohn's disease of the pouch
Study: NCT04975191

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Resources
Description: Participants will be provided a list of resources available at VCU that are intended to support student success

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Personalized Feedback Program (PFP)
Description: Participants will complete an interactive online program that explores their personality-related traits to provide personalized recommendations for success

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Personalized Feedback Program (PFP)
Description: Participants will complete an interactive online program that explores their personality-related traits to provide personalized recommendations for success

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Substance Use Feedback Program (BMI)
Description: Participants will complete an online program based on brief motivational intervention (BMI) content/principles that explores their current substance use patterns to make personalized recommendations for success

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Substance Use Feedback Program (BMI)
Description: Participants will complete an online program based on brief motivational intervention (BMI) content/principles that explores their current substance use patterns to make personalized recommendations for success
Study: NCT05719792

Intervention type: PROCEDURE
Intervention: Transforaminal Epidural Steroid Injection
Description: In the TFESI group, all patients were positioned prone. The injection site was cleaned with povidone-iodine 3 times and a sterile drape was applied. Short-acting local anesthesia (3 mL of 2% prilocaine) was applied to the skin and subcutaneous tissue. A 3.5-inch, 22-gauge spinal needle was inserted just below the pedicle. It was advanced into the subpedicular space using the coaxial technique under the intermittent guidance of fluoroscopy. The needle position was confirmed through a lateral view. Using lateral views, the needle was placed at the posterior one-third of the foramen. Using the anteroposterior view, one to 2 mL of the contrast agent (300 mg/50 mL iohexol) was given and the distribution pattern was visualized. Once the epidural distribution of the contrast agent was confirmed without vascular flow, a mixture of 8 mg (two mL) of dexamethasone, 2 mL of physiological saline, and 1 mL (0.5%) of bupivacaine hydrochloride was injected.

Intervention type: PROCEDURE
Intervention: Erector Spina Plane Block
Description: Patients are placed in the prone position to determine the vertebrae in the middle of the involved area. Following the provision of aseptic conditions, the spinous process of the vertebral midline is visualized using a high-frequency (8 MHz) linear ultrasound (USG) probe. The transverse process is, then, visualized approximately at the 3 cm lateral from the midline and the erector spinae muscle is visualized on it. The 22-gauge 50 mm block needle is advanced towards the in-plane section craniocaudally and the transverse process is touched. Then the needle is then withdrawn minimally to confirm that it is between the erector spinae muscle and the transverse process through hydrodissection. Following that, 5 mL from 0.5% bupivacaine hydrochloride, 8 mg dexamethasone and 3 ml saline is administered and local anesthetic spread is confirmed by USG.
Study: NCT06501430

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heating Therapy
Description: Heating Therapy will be performed on subjects along with PNF Exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heating Therapy
Description: Heating Therapy will be performed on subjects along with PNF Exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Soft tissue Release
Description: Manual Soft tissue Release will be performed on subjects along with PNF Exercises.
Study: NCT05199376

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryotherapy
Description: The cryotherapy treatment lasts approximately 30 minutes during which two 10-minute freezing cycles are performed, separated by a reheating phase. During the freezing phases, the temperature is lowered below -40°C in the ablation zone, a temperature that is lethal for the cells.
Study: NCT04848714

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANAWIDOW [antivenin latrodectus (black widow) equine immune F(ab)2] lyophilized powder for solution 10 mL
Description: Antivenin latrodectus (black widow) equine immune F(ab)2\] lyophilized powder for solution 10 mL for intravenous use \[parenteral formulation\]; hence, a single-dose fasting pharmacokinetic study is planned.
Study: NCT06012279

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin 10mg Tab
Description: Dapagliflozin is a drug that works through inhibition of sodium glucose transporter-2 resulting in glucosuria.
Study: NCT05597644

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Trans-arterial uterine artery embolization
Description: transarterial angioembolization of uterine artery
Study: NCT06037850

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test orthokeratology lens
Description: Randomized to test orthokeratology lens worn during sleep every night

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control orthokeratology lens
Description: Randomized to control orthokeratology lens worn during sleep every night
Study: NCT04517786

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MINIject CS627 implant
Description: MINI SO627 is an integrated system comprising a minimally-invasive Glaucoma Drainage Implant (CS627) and a single operator delivery tool.~The delivery tool is a single-use tool, designed for inserting the CS627 implant into the suprachoroidal space in the eye.
Study: NCT05883332

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Self-Administered Nitrous Oxide
Description: Nitrous oxide administered at concentrations of mild sedation (20-50%)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Self-Administered Nitrous Oxide
Description: Nitrous oxide administered at concentrations of mild sedation (20-50%)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxygen
Description: 100% oxygen at 10 Liters/minute

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxygen
Description: 100% oxygen at 10 Liters/minute
Study: NCT06351098

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: nap
Description: Children are nap promoted
Study: NCT06183372

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lemon balm
Description: 300mg Lemon balm and Maltoxdextrin capsules Other Name: Melissa Officinalis L.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 300mg Maltodextrin capsules
Study: NCT04763486

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cefazolin (Cefamezin)
Description: Cefamezin 2 gr within 6 hour of delivery
Study: NCT05425654

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab, Methotrexate, Vincristine, Procarbazine, Lenalidomide
Description: The initial treatment will consist of cycles of 14 days. Each cycle will start with rituximab, which will be given by vein on day 1. On day 2 you will receive: Methotrexate will be given by vein over 2 to 3 hours and vincristine will be given as a single injection over a few minutes. Procarbazine and Lenalidomide are a pill that you will take at bedtime for 7 nights starting on day 2. Procarbazine and Lenalidomide are only given every other cycle. During each cycle, you will be in the hospital. After the second cycle of chemotherapy, PBPCs will be collected. You will be hospitalized again for high-dose chemotherapy and receive supportive medications to help avoid complications, including antibiotics and blood transfusions. Busulfan, carmustine and cyclophosphamide will be given to you for 5 days. After break of 1 day, we will return your PBPC (or bone marrow) to you through a vein. You will be in the hospital for at least 3 weeks.
Study: NCT06501430

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Soft tissue Release
Description: Manual Soft tissue Release will be performed on subjects along with PNF Exercises.
Study: NCT05440890

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best current rehabilitation protocol
Description: Inflamation control and edema with physical agents, recover full pasive and active range of motion, normalize gait pattern, lower limb strengthening (specially quadriceps and hamstrings), neuromuscular control training, cycling, landings and running.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best current rehabilitation protocol
Description: Inflamation control and edema with physical agents, recover full pasive and active range of motion, normalize gait pattern, lower limb strengthening (specially quadriceps and hamstrings), neuromuscular control training, cycling, landings and running.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross-training protocol
Description: Beginning on 2º week after ACLR, 3 times per week during 8 weeks, based on isotonic exercise at least to 80% of 1RM in leg extension. 5 sets o 6 repetions with 1,5 - 2 minutes between series.
Study: NCT05991037

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood sampling for psychoactive drugs dosage
Description: 4 blood samples for psychoactive drugs identification and dosage will be taken on arrival at the emergency room during fall management

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sampling for psychoactive drugs dosage
Description: 4 blood samples for psychoactive drugs identification and dosage will be taken on arrival at the emergency room during fall management
Study: NCT05832112

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: VATS/RATS lobectomy
Description: Consenting patients will undergo lobectomy by OTC RATS following the exact standard steps usually done by VATS/RATS, aside from the ports that will be placed in the subcostal plane. The characteristics of both the patient and the case, will determine the number of incisions from 1-4.~The Davinci Xi® surgical system will be used to perform the lobectomy through the ports using the standard technique with an anterior approach. Once the procedure is completed, the robotic arms and ports will be removed from the chest and figure-of-8 stitches with non absorbable sutures will be placed to close the diaphragm at the site of insertion. A 24 Fr soft chest tube will be left in place, as in the standard VATS/RATS lobectomy procedure. The incision closure will be done in a standard manner.
Study: NCT05230537

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iptacopan (LNP023)
Description: oral capsules

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral capsules
Study: NCT06102993

Intervention type: OTHER
Intervention: Non-interventional study
Description: The only intervention is to analyze serum molecules of patients with COPD and controls without COPD.

Intervention type: OTHER
Intervention: Non-interventional study
Description: The only intervention is to analyze serum molecules of patients with COPD and controls without COPD.

Intervention type: OTHER
Intervention: Non-interventional study
Description: The only intervention is to analyze serum molecules of patients with COPD and controls without COPD.

Intervention type: OTHER
Intervention: Non-interventional study
Description: The only intervention is to analyze serum molecules of patients with COPD and controls without COPD.

Intervention type: OTHER
Intervention: Non-interventional study
Description: The only intervention is to analyze serum molecules of patients with COPD and controls without COPD.

Intervention type: OTHER
Intervention: Non-interventional study
Description: The only intervention is to analyze serum molecules of patients with COPD and controls without COPD.
Study: NCT05899231

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation Programming
Description: 12-weeks of online prehabilitation programming including:~1.12 weeks of nutrition programming focused on achieving a guideline- based protein intake of 1.2-1.5 g/kg/day. Participants will participate in a dietitian assessment and 0-2 dietitian follow-ups stratified by risk and 5 virtual group nutrition classes. Participants will be provided with a whey protein powder supplement - dosing stratified by risk.~2.10 weeks of exercise programming focused on completion of 3 full- body resistance/aerobic exercise sessions weekly (1 or 2 virtual group classes as per patient preference + 1 or 2 pre-recorded home exercise videos).~3.12 weeks of acceptance and commitment therapy based educational videos and online activities focused on reducing stress and anxiety and improving motivation and adherence.
Study: NCT03960125

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photodynamic Therapy
Description: Blue Light Therapy Exposure

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photodynamic Therapy
Description: Blue Light Therapy Exposure

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4% Imipramine
Description: A tricyclic antidepressant (TCA) medication. Though it is usually taken orally, topical preparations (4%) has use in topical anesthetics and anti-pain medicaments.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4% Imipramine
Description: A tricyclic antidepressant (TCA) medication. Though it is usually taken orally, topical preparations (4%) has use in topical anesthetics and anti-pain medicaments.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Base Cream
Description: Control to 4% Imipramine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Base Cream
Description: Control to 4% Imipramine
Study: NCT06174467

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SEELearning Training
Description: This group will receive the Learning Training for Hearts and Minds and will be submitted to assessments and questionnaires that measure the improvement of well-being, reduction of stress and literacy in the contents and human values taught in the training.~The program aims to increase participants' awareness, compassion and engagement. Compassion refers to cultivating a way of relating to oneself, others and humanity through kindness, empathy and genuine care for the happiness and suffering of these individuals. Awareness refers to cultivating a detailed, first-person understanding of thoughts, feelings, and emotions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Waiting list group of the intervention
Description: The group will remain on a waiting list and will respond to questionnaires about well-being and other items before receiving the training and, in the second semester, during the period in which it will receive the training
Study: NCT06197165

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Targeted Shiatsu
Description: demonstrate the beneficial impact targeted Shiatsu compared with a comfort Shiatsu

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Targeted Shiatsu
Description: demonstrate the beneficial impact targeted Shiatsu compared with a comfort Shiatsu
Study: NCT06107803

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Roluperidone 64 mg
Description: 64 mg/day oral
Study: NCT05305742

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Instrument Design
Description: Research the effect of different instrument designs on root canal preparation by evaluating bacterial count reduction and post-operative pain

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instrument Design
Description: Research the effect of different instrument designs on root canal preparation by evaluating bacterial count reduction and post-operative pain
Study: NCT06107803

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Roluperidone 64 mg
Description: 64 mg/day oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olanzapine 10 MG
Description: 10 mg/day oral
Study: NCT06282783

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topiramate
Description: Single dose of 400mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topiramate
Description: Single dose of 400mg
Study: NCT06551766

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photosensitive hydrogel
Description: In the photosensitive hydrogel group, the anastomosis of the lacrimal cyst mucosal flap and the nasal mucoperiosteal flap was achieved by photosensitive hydrogel.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 6-0 absorbable stitches
Description: In the suture fixation group, the anastomosis of the lacrimal cyst mucosal flap and the nasal mucoperiosteal flap was achieved by two stitches using 6-0 absorbable wire.
Study: NCT05998148

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual phone appointment visits
Description: Patient will have post-operative appointments that place with telemedicine. The visits will will be virtual phone appointments scheduled at approximately 6 weeks, 12 weeks, and 6 months after surgery.
Study: NCT04976413

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eye Movement Desensitization and Reprocessing (EMDR) psychotherapy
Description: Experimental arm will receive eight phase EMDR treatment using manualized standard protocol. Selection of targets for reprocessing through EMDR will be made according to adaptive information processing model's postulations, that links traumatic events with the symptoms of depression and anxiety. Time period allocated to EMDR treatment is 12-14 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Counselling as usual
Description: Control arm will receive counseling as usual for 12-14 weeks
Study: NCT05333731

Intervention type: DRUG
Intervention: Oxytocin
Description: In the two groups, if spontaneous labor does not occur after PROM, they all receive the oxytocin for up to 24h.

Intervention type: DRUG
Intervention: Oxytocin
Description: In the two groups, if spontaneous labor does not occur after PROM, they all receive the oxytocin for up to 24h.
Study: NCT06282146

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: transcranial magnetic stimulation
Description: non-invasive form of brain stimulation
Study: NCT05198518

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Microcurrent TENS device
Description: The study device is a handheld micro-current TENS emitter intended to be used for the relief of postoperative pain after FESS. The design of the study device was optimized to provide transcutaneous nerve stimulation to the regional areas associated with the sinuses.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Device
Description: The sham device appears and operates identically to the active device, including indicator lights and haptic vibration, however it emits a weak direct current that is non-therapeutic.
Study: NCT05258383

Intervention type: OTHER
Intervention: 3D maps of physical doses
Description: 3D maps of physical doses delivered to organs by positioning imaging will be calculated based on the patient's CT image used by the treatment planning system (dosimetric calculation performed by Monte Carlo method).

Intervention type: OTHER
Intervention: 3D maps of physical doses
Description: 3D maps of physical doses delivered to organs by positioning imaging will be calculated based on the patient's CT image used by the treatment planning system (dosimetric calculation performed by Monte Carlo method).

Intervention type: OTHER
Intervention: 3D maps of physical doses
Description: 3D maps of physical doses delivered to organs by positioning imaging will be calculated based on the patient's CT image used by the treatment planning system (dosimetric calculation performed by Monte Carlo method).

Intervention type: OTHER
Intervention: 3D maps of physical doses
Description: 3D maps of physical doses delivered to organs by positioning imaging will be calculated based on the patient's CT image used by the treatment planning system (dosimetric calculation performed by Monte Carlo method).

Intervention type: OTHER
Intervention: 3D maps of physical doses
Description: 3D maps of physical doses delivered to organs by positioning imaging will be calculated based on the patient's CT image used by the treatment planning system (dosimetric calculation performed by Monte Carlo method).
Study: NCT05465655

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ECG monitoring for Conduction Disturbances
Description: Continuous ECG monitoring of Conduction Disturbances in patients undergoing TAVR procedure
Study: NCT05232812

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 3-[11C]-OHB
Description: The PET tracer 3-\[11C\]-OHB is used to quantify 3-hydroxybutyrate uptake
Study: NCT04368689

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Floatation-based reduced environmental stimulation therapy
Description: Completion of 3 float session that can last for up to 90 minutes each session, each spaced approximately one week apart
Study: NCT05343546

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion
Description: Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion within seven days of giving Misoprostol Early insertion or 2-4 weeks after Misoprostol use Standard insertion

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion
Description: Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion within seven days of giving Misoprostol Early insertion or 2-4 weeks after Misoprostol use Standard insertion