TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06192082

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: The conscious sedation group
Description: The conscious sedation group (Group A) received sufentanil 0.05-0.1 5 minutes before examination μ G/kg, administration time 30 seconds, 1-2 mg of midazolam administered 2 minutes before examination; Evaluate the patient's MOAA/S score, insert a digestive endoscope at 2-3 minutes, and add 1-2mg of midazolam if the patient is unable to tolerate coughing or movement during the examination. Reevaluate the MOAA/S score, and continue the operation after 2-3 minutes;

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous general anesthesia group
Description: Intravenous general anesthesia group (Group B): sufentanil 0.05-0.1 μ G/kg, administration time 30 seconds, 1mg/kg of propofol administered 2 minutes before examination. Depending on the patient's sleep status, 10mg of propofol can be administered every 30 seconds; Evaluate the patient's MOAA/S score. At 0-1 points, a digestive endoscope is inserted. If there is coughing or physical activity during the examination that the patient cannot tolerate, propofol 10-20mg can be administered multiple times. Evaluate the MOAA/S score again, and continue the operation after 0-1 points.
Study: NCT06020092

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone augmentation with I-BCP
Description: The extraction socket will be filled after tooth extraction with I-BCP, in order to achieve bone regeneration and prevent volume loss after tooth extraction.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bone augmentation with BX
Description: The extraction socket will be filled after tooth extraction with BX, in order to achieve bone regeneration and prevent volume loss after tooth extraction.
Study: NCT05982184

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music
Description: Patient preferred music listened to through earpieces or headphones using patients' own hardware and software.
Study: NCT06308679

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Empagliflozin 10 mg tablets
Description: Empagliflozin 10 mg tablets (test drug)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 10 mg tablets
Description: Empagliflozin 10 mg tablets (test drug)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JARDIANCE®
Description: Empagliflozin 10 mg tablets (reference drug)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JARDIANCE®
Description: Empagliflozin 10 mg tablets (reference drug)
Study: NCT03664466

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: astaxanthin
Description: astaxanthin capsules 12 mg twice daily

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo capsules twice daily
Study: NCT05897567

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: resistance training
Description: All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: resistance training
Description: All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ketogenic diet
Description: Subjects allocated to the ketogenic diet arm (KD group) consume less than 50 g of carbohydrates per day.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: western diet
Description: Subjects allocated to the western diet arm (WD group) consume a standard diet based on 55% of their daily calories from carbohydrates.
Study: NCT04586725

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Encouragement a one minute intervals
Description: Patients will perform the six exercise tests with encouragement at one minute intervals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Encouragement a one minute intervals
Description: Patients will perform the six exercise tests with encouragement at one minute intervals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Encouragement a two minute intervals
Description: Patients will perform the six exercise tests with encouragement at two minute intervals

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Encouragement a two minute intervals
Description: Patients will perform the six exercise tests with encouragement at two minute intervals
Study: NCT04605978

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S95011 concentrate for solution for infusion
Description: IV administration every 2 weeks until week 4 and then every 3 weeks until week 10.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo concentrate for solution for infusion
Description: IV administration every 2 weeks until week 4 and then every 3 weeks until week 10.
Study: NCT06414486

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplement group
Description: One tablet per day for 3 weeks consumed for subjects randomized in the Dietary supplementation group. This will lead to an intake of 200mg per day of Red Panax Ginseng (corresponding to 22.4mg of ginsenosides and 20.2mg of rare ginsenosides).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo group
Description: One tablet per day consumed for 3 weeks for subjects randomized in the Control group. The product is composed of rice flour (50mg) and brown sugar (150mg).
Study: NCT05559502

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HFNO group
Description: HFNO therapy make possible to perform tubeless anesthesia, providing perfect exposure of structure of the vocal cords.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ET group
Description: Endotracheal tube is a plain tube, which is most commonly used in general anesthesia.
Study: NCT04702633

Intervention type: OTHER
Intervention: Results obtained by biopsy and MRI results.
Description: Results obtained by biopsy and MRI results.

Intervention type: OTHER
Intervention: Results obtained by biopsy and MRI results.
Description: Results obtained by biopsy and MRI results.

Intervention type: OTHER
Intervention: Clinical data
Description: Clinical data

Intervention type: OTHER
Intervention: Clinical data
Description: Clinical data
Study: NCT05100264

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vaginal washing with 5% acetic acid
Description: Induction of labor (vaginal tablet dinoprostone and vaginal washing with 5% acetic acid)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Vaginal washing with 0.9% NS
Description: Induction of labor (vaginal tablet dinoprostone and vaginal washing 0.9% NS)
Study: NCT04924283

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tetris and Assessments
Description: Participants will complete assessments on their phone to rate cravings for alcohol. Participants will complete a visual cognitive interference task (i.e., play Tetris on their phone) after endorsing a alcohol craving, and then re-rate craving after the task.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Assessment Only
Description: Participants will complete assessments on their phone to rate cravings for alcohol.
Study: NCT05452928

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acyclovir 50 MG/ML
Description: Patients are randomised to active treatment with IV acyclovir with the possibility of step-down to valacyclovir. If the treating physician prefers, initial IV treatment can be omitted and the patient can be treated with valacyclovir throughout the study period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo either in IV formulation or as tablets identical to valacyclovir tablets.
Study: NCT05649930

Intervention type: OTHER
Intervention: Functional power training
Description: The training consists of weighted running and walking exercises performed at high-velocity and is given three times a week for 12 weeks.
Study: NCT05000554

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neoadjuvant Therapy
Description: Drug:~Camrelizumab 200mg,d1，Repeat every 21 days for 3 courses； Oxaliplatin 130mg/m² ,d1;S-1 40-60mg,Bid, d1-14; S-1: bsa\<1.25m2,40mg/time，twice a day；bsa1.25\~1.5m2，50mg/time，twice a day；bsa≥1.5m2,60mg/次，twice a day，d1-d14；~Procedure: Gastric cancer resection Distal gastrectomy combined with D2 lymph node dissection
Study: NCT05446324

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gallium-68-tilmanocept
Description: All participants receive a cervical injection with 10 MBq 68Ga-tilmanocept in an outpatient setting (at least one week) before surgery. Within 30-90 minutes post-injection a PET with contrast enhanced CT is performed (PET/CT). Data (i.e. detection rate) from the imaging modalities are collected.
Study: NCT05477329

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lenses
Description: The test lens is manufactured in a standard FreeForm technology (exactly like a standard progressive addition lens which is similar in terms of the graduall power profile induced in both lens). It does not demand any special manufacturing processes.
Study: NCT05473754

Intervention type: BEHAVIORAL
Intervention: SUPER digital platform
Description: SUPER digital platform was implemented to ensure synergy between ASD families, health services, and schools through different tools to share rehabilitative and educational objectives and strategies. It was designed following the ASD International Guidelines and the recommendations of the ICF-CY and was organized into two areas: General (to promote scientific knowledge on ASD) and Personalized (restricted virtual space for groups of users following an individual with ASD).
Study: NCT04258488

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin K antagonist(warfarin)
Description: For 12months, keep the international normalized ratio (INR) 1.7-3.0
Study: NCT05477329

Intervention type: DEVICE
Group type: OTHER
Intervention: Lenses
Description: The test lens is manufactured in a standard FreeForm technology (exactly like a standard progressive addition lens which is similar in terms of the graduall power profile induced in both lens). It does not demand any special manufacturing processes.
Study: NCT04941222

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: With robotic seal PARO
Description: The PARO robot will be made available to the patient by the caregiver in charge of the patient for 5mn before a toilet and during the duration of the care (about 10mn), at the frequency of twice a week for 16 weeks
Study: NCT04579874

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: LIVERFASt
Description: blood draw
Study: NCT04787757

Intervention type: PROCEDURE
Intervention: Percutaneous cardiac procedure
Description: Collection and analysis of intraprocedural information to provide artificial intelligence algorithms
Study: NCT05461781

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: distal radial artery
Description: primary percutaneous coronary intervention via distal radial aretry

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: proximal radial aretry
Description: primary percutaneous coronary intervention via proximal radial aretry
Study: NCT06518421

Intervention type: BEHAVIORAL
Intervention: Neuropsychological assessments
Description: * Pain questionnaires such as Numerical Pain Rating Scale is one of the most widely used multidimensional pain scales to assesses a person's pain based on the words they use to describe their pain.~* Battery of Cognitive questionnaires = The cognitive test battery was designed to assess key cognitive abilities including attention, concentration, verbal learning and memory, verbal fluency, working memory and executive function as well as global cognitive functioning and fear and anxiety~* Mnemonic Simulation Test and Rey Auditory Verbal Learning Test are the neuropsychological assessments designed to evaluate recognition and verbal memory, respectively. Both tasks have been shown to be very sensitive to hippocampal engagement and damage.~* Memory-recall interview is an interview for the interviewees to recall the event from different perspectives, such as from the preadmission date, 2-week post- and 6-month post-surgical date. This supports the memory retrieval process.

Intervention type: BEHAVIORAL
Intervention: Neuropsychological assessments
Description: * Pain questionnaires such as Numerical Pain Rating Scale is one of the most widely used multidimensional pain scales to assesses a person's pain based on the words they use to describe their pain.~* Battery of Cognitive questionnaires = The cognitive test battery was designed to assess key cognitive abilities including attention, concentration, verbal learning and memory, verbal fluency, working memory and executive function as well as global cognitive functioning and fear and anxiety~* Mnemonic Simulation Test and Rey Auditory Verbal Learning Test are the neuropsychological assessments designed to evaluate recognition and verbal memory, respectively. Both tasks have been shown to be very sensitive to hippocampal engagement and damage.~* Memory-recall interview is an interview for the interviewees to recall the event from different perspectives, such as from the preadmission date, 2-week post- and 6-month post-surgical date. This supports the memory retrieval process.

Intervention type: DIAGNOSTIC_TEST
Intervention: MR Imaging
Description: Magnetic Resonance Imaging is a noninvasive medical imaging test that produces detailed images of almost every internal structure in the human body, including the organs, bones, muscles and blood vessels. MRI scanners create images of the body using a large magnet and radio waves.

Intervention type: DIAGNOSTIC_TEST
Intervention: MR Imaging
Description: Magnetic Resonance Imaging is a noninvasive medical imaging test that produces detailed images of almost every internal structure in the human body, including the organs, bones, muscles and blood vessels. MRI scanners create images of the body using a large magnet and radio waves.
Study: NCT04852874

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided Quadratus Lumborum Block
Description: Low dose spinal anesthesia will be done at L3-4 lumbar vertebrae with bupivacaine 2.5 mg (0.5 ml Marcaine 0.5%) and fentanyl 25 µgm (0.5 ml) of fentanyl amp (100 µgm/ 2ml) to be added to 1.5 - 2 ml of free water to form total volume of 2.5- 3ml according to the patient height aiming level of T6 sensory level.~Quadratus lumorum block:~After 4 to 5 minutes, ultrasound guided quadratus lumborum block (QL 1,2,3) will be done unilaterally, using low-frequency convex probe, taking into consideration the total volume of injectate not exceeding 0.4 ml /kg of (bupivacaine 0.5%) to avoid local anesthesia systemic toxicity. This is equal to 0.8 ml/kg of (bupivacaine 0.25%).~After confirming the correct position of the needle, 0.2-3 ml/kg of 0.25% bupivacaine plus 1.5 mg dexamethasone and magnesium sulphate of 100 mg will be injected in each site of the QL 1,2,3 using the lean body weight. The lean body weight will be calculated by omni lean body mass online calculator.
Study: NCT06413836

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: aPDT
Description: Mechanized endodontic treatment using an endodontic rotatory device (DENTSPLY) will be used to prepare the root canals. Following, it will be applied the methylene blue solution in surfactant medium and after 1 minute a diode laser equipment (DMC THERAPY/EC, Sao Carlos, Brazil) will be used to shine light at a wavelength of 660nm, 100 mW (miliWatts) and irradiation time of 3 min. CaOH (calcium hydroxide) paste will be applied at the root canals canals as a long-term dressing for endodontic treatment..

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endodontic treatment
Description: Mechanized endodontic treatment using an endodontic rotatory device (DENTSPLY) will be used to prepare the root canals. Following, it will be applied the methylene blue solution in surfactant medium and after 1 minute a diode laser equipment (DMC, THERAPY/EC, Sao Carlos, Brazil) will be used with an aluminium foil at the tip of the equipment to block light and use during 3 min as study group. CaOH (calcium hydroxide) will be applied at the root canals as a long-term dressing for endodontic treatment.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Endodontic treatment
Description: Mechanized endodontic treatment using an endodontic rotatory device (DENTSPLY) will be used to prepare the root canals. Following, it will be applied the methylene blue solution in surfactant medium and after 1 minute a diode laser equipment (DMC, THERAPY/EC, Sao Carlos, Brazil) will be used with an aluminium foil at the tip of the equipment to block light and use during 3 min as study group. CaOH (calcium hydroxide) will be applied at the root canals as a long-term dressing for endodontic treatment.
Study: NCT05311852

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: palmitoylethanolamide co-ultramicronized with antioxidant flavonoid luteolin (PEA-LUT)
Description: assumption of the product at dosage of 700/70 mg 2 time/day for 8 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: assumption of a placebo product 2 time/day for 8 weeks
Study: NCT06193811

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (intended commercial formulation (iCF))
Description: Avenciguat (BI 685509) (intended commercial formulation (iCF))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (intended commercial formulation (iCF))
Description: Avenciguat (BI 685509) (intended commercial formulation (iCF))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (intended commercial formulation (iCF))
Description: Avenciguat (BI 685509) (intended commercial formulation (iCF))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (intended commercial formulation (iCF))
Description: Avenciguat (BI 685509) (intended commercial formulation (iCF))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (trial formulation 2 (TF2))
Description: Avenciguat (BI 685509) (trial formulation 2 (TF2))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (trial formulation 2 (TF2))
Description: Avenciguat (BI 685509) (trial formulation 2 (TF2))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (trial formulation 2 (TF2))
Description: Avenciguat (BI 685509) (trial formulation 2 (TF2))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avenciguat (BI 685509) (trial formulation 2 (TF2))
Description: Avenciguat (BI 685509) (trial formulation 2 (TF2))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: esomeprazole
Description: esomeprazole (Nexium mups)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: esomeprazole
Description: esomeprazole (Nexium mups)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: esomeprazole
Description: esomeprazole (Nexium mups)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: esomeprazole
Description: esomeprazole (Nexium mups)
Study: NCT05878184

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC291
Description: SC291 is an allogeneic CAR-T cell therapy
Study: NCT06414057

Intervention type: OTHER
Intervention: Offering opportunistic HPV vaccine during routine sexual health clinic visits
Description: Investigators will offer Gardasil-9 and HPV self-swab screening to up to 500 individuals across the three study sites, aiming to recruit 120-180 individuals within each of the three participating health boards over a 6-9 month timeframe. Participants will be asked to provide a vaginal swab sample for baseline HPV testing.
Study: NCT05194904

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: This is a prospective randomised clinical study designed to assess the effect of intravenous ketorolac versus intravenous dexmedetomidin on postoperative pain after hypospadias repair in children

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: This is a prospective randomised clinical study designed to assess the effect of intravenous ketorolac versus intravenous dexmedetomidin on postoperative pain after hypospadias repair in children
Study: NCT05924386

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: patients reciveing all on 4 fixed mandibular prosthesis usimg conventionally screw retained multiunit abutments
Description: Multiunit abutments is considered a gold standard screw retained abutments. Multi-unit abutments are used to correct for varying heights among the implants, to establish a level restorative platform for the prosthesis, as well as to situate the implant connection even with or just below the gingival surface. Also they are used to correct the angulation of implants, helping to keep the screw access holes away from the facial surfaces of the restoration, and facilitate the path of insertion of prosthesis.
Study: NCT05063708

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental: traditional dysphagia therapy plus Neuromuscular electrostimulation
Description: In the present study, VitalStim equipment will be used (VitalStim Therapy; Chattanooga Group, Chattanooga, TN, USA). Therapists received additional training and information on NMES by an experienced laryngologist certified to use surface electrical stimulation.
Study: NCT05924386

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: all on 4 fixed mandibular prosthesis using OTbridge attachment system
Description: The OT bridge attachment system introduced by (Rhein 83) is a global, well-established system used in the removable prosthetic protocols, the presence of seeger acetal ring placed between the sub-equatorial area of the OT Equator and the cylindrical Extragrade abutment compensates the space between the extragrade abutment and the OT equator attachment correcting the minor misalignments that produced during the prosthetic procedure and resulting in more passive fit.
Study: NCT05063708

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Comparator: Traditional dysphagia therapy plus sham Neuromuscular electrostimulation
Description: Therapists received additional training and information on NMES by an experienced laryngologist certified to use surface electrical stimulation. The training was given according to the manual of the manufacturer, the VitalStim certification course (http://www.vitalstim.com).
Study: NCT04827485

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Gluteal squeeze
Description: During procedure, the doctor performing colonoscopy will ask for gluteal pressure. The technician will perform the maneuver, but the doctor will be blinded as the arms of the technician along with the patients behind are covered by a towel.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: No squeeze
Description: During procedure, the doctor performing colonoscopy will ask for gluteal pressure. The technician will not perform the maneuver, but the doctor will be blinded as the arms of the technician along with the patients behind are covered by a towel.