TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04909177

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Smartphone application (app) in combination with headset
Description: The intervention oVRcome is self-help VRET for specific phobia, that is delivered through a smartphone application (app) in combination with headset that holds the smartphone and uses 360º video. oVRcome includes 6 modules of psychoeducation, relaxation, mindfulness, cognitive techniques, exposure through VR, and a relapse prevention module which are aimed to be completed weekly.
Study: NCT05927194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Using the Connect
Description: Using the Connect (UTC) is an innovative, game-based intervention for youth to develop skills in adulthood preparation topics such as communication, decision making and accessing information.
Study: NCT06507059

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cabotegravir/rilpivirine (600mg/ 900mg)
Description: Immediate switch from oral antiretroviral to long-acting injectables
Study: NCT04924985

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Non-Physiological Feedback CPR
Description: Non-physiologically guided CPR using AV feedback (integrated into defibrillators)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiological Feedback CPR
Description: Physiological feedback CPR using an optimal regional O2 Saturation (rSO2), End-tidal CO2 (ETCO2) or combined (rSO2/ETCO2) target
Study: NCT04744961

Intervention type: OTHER
Intervention: SCAR-Q survey
Description: Telephone survey

Intervention type: OTHER
Intervention: SCAR-Q survey
Description: Telephone survey
Study: NCT05981508

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Together, Eating and Activity, Matter Plus (TEAM+) Online
Description: TEAM+ is a 3-month, family enhanced behavioral weight loss (BWL) intervention designed for Black adults consisting of an online family dyadic skills training and in-person core behavioral weight loss sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Together, Eating and Activity, Matter Plus (TEAM+) In-Person
Description: TEAM+ is a 3-month, family enhanced behavioral weight loss (BWL) intervention designed for Black adults consisting of in-person family dyadic skills training and core behavioral weight loss sessions.
Study: NCT06507059

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antiretroviral Combinations
Description: Standard all-oral antiretroviral combinations
Study: NCT05669859

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The rehabilitation program designed in our study was based on the development of core muscle control and dynamic stabilization of the spine, which is generally required by patients. All exercises were combined with controlled breathing, focusing on the mobility of the extremities and the activity of multiple muscle groups.~Our program created in this direction will start with face-to-face patient education; For 8 weeks, will be carried out remotely online under the supervision of a physiotherapist.On non-telerehabilitation days, they will be asked to keep an exercise diary, instructed to practice the exercise approach presented in sessions at home daily in 20-minute periods. The exercise diary will be checked during online sessions.
Study: NCT06096649

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Topical Vehicle + Zinc Di-(dibutyryl lisinate)
Description: Instructions: Apply to the entire face twice daily - morning and evening

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Topical Vehicle
Description: Instructions: Apply to the entire face twice daily - morning and evening
Study: NCT04791436

Intervention type: DIAGNOSTIC_TEST
Intervention: Gustatory and olfactory function test
Description: The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.

Intervention type: DIAGNOSTIC_TEST
Intervention: Gustatory and olfactory function test
Description: The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.

Intervention type: DIAGNOSTIC_TEST
Intervention: Gustatory and olfactory function test
Description: The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.

Intervention type: DIAGNOSTIC_TEST
Intervention: Molecular assessment of saliva
Description: Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.

Intervention type: DIAGNOSTIC_TEST
Intervention: Molecular assessment of saliva
Description: Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.

Intervention type: DIAGNOSTIC_TEST
Intervention: Molecular assessment of saliva
Description: Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.
Study: NCT06157866

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: During the treatment sessions the acupuncturist will insert needles in several locations aimed to reduce the patient's fibromyalgia pain. A low-amplitude, sub-sensory electrical current will be activated by the acupuncturist.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electroacupuncture
Description: During the treatment sessions the acupuncturist will insert needles in several locations aimed to reduce the patient's fibromyalgia pain. A low-amplitude, sub-sensory electrical current will be activated by the acupuncturist.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Training
Description: Cognitive training with a pain specialist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education Training
Description: Education training with a pain specialist.
Study: NCT05385666

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collaborative cares
Description: coordinate care between city medicine and specialized psychiatric care to improve the management of common mental disorders
Study: NCT05925777

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: THEAL (Mectronic, Bergamo)
Description: laser therapy high intensity
Study: NCT06059235

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pharmaceutical care
Description: consultation with a pharmacist performing advanced pharmaceutical care : Package of clinical pharmacy activities including :~Medication history (during assessment consultation) Medication review and consultation with the geriatrician Therapeutic education (during results consultation) Shared decision (at results consultation) One-week follow-up call + usual care
Study: NCT05666349

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: 100 mg, 200 mg, or 300mg oral niraparib once daily.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-irradiation (re-RT)
Description: Intensity modulated radiotherapy (IMRT)-based re-RT for a total dose of 35 Gy in 10 daily fractions.
Study: NCT05942144

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise-snacks program
Description: Subjects in the exercise-snacks group will perform 4 exercise-snacks sessions per working day for 4 weeks. These sessions will consist of 80 one-to-one walks to be completed as quickly as possible. They will also receive information about their attitudes to physical activity.
Study: NCT04766463

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554 Injection
Description: SHR8554 Injection; high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554 Injection
Description: SHR8554 Injection; low dose

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline Solution

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Morphine
Study: NCT06391099

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Undergo standard of care diet

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and stool sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Under CT

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary Intervention
Description: Undergo ketogenic diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Activity
Description: Receive coaching support

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Glucose Measurement
Description: Undergo blood glucose testing

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketone Measurement
Description: Undergo ketone measurement

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT04648930

Intervention type: DRUG
Intervention: Xolair
Description: There was no treatment allocation. Patients administered Xolair by prescription that started before inclusion of the patient into the study were enrolled.
Study: NCT05639270

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: use of an auricular electrode
Description: Use of the auricular electrode throughout the duration of the study (30minutes/day) combined with assessment of pain, tolerance, vagal tone.
Study: NCT06290856

Intervention type: DIAGNOSTIC_TEST
Intervention: Multiplex PCR-test for circulating tumor DNA
Description: All recruited patients will be tested for
Study: NCT05216536

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT06006416

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fenugreek Fibre
Description: Daily dose of 2 x 10g per day with/in food
Study: NCT04733157

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid injection
Description: Tranexamic 1g administered intravenously at the onset of skin incision at caesarean section

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline placebo
Description: 10ml of normal saline will be administered intravenously at onset of skin incision at caesarean section to the placebo group
Study: NCT06374329

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interceptive Slow Maxillary Expansion with removable plates
Description: Interceptive Slow Maxillary Expansion with removable plates (see Willems et al 2023) https://doi.org/10.1093/ejo/cjad014

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interceptive Slow Maxillary Expansion with removable plates
Description: Interceptive Slow Maxillary Expansion with removable plates (see Willems et al 2023) https://doi.org/10.1093/ejo/cjad014
Study: NCT05157594

Intervention type: BIOLOGICAL
Intervention: Blood sample
Description: Evaluation of plasma hPG80 concentrations by fasting blood samples. A total of seven 5 mL blood samples will be taken: Before radiation therapy; at the end of radiation therapy; at cycle 3 of chemotherapy; at cycle 6 of chemotherapy; 3 months after the end of treatment; 6 months after the end of treatment; and 9 months after the end of treatment.
Study: NCT06038838

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tioga TMVR System
Description: A bioprosthetic mitral valve, as part of the Tioga TMVR System, is implanted percutaneously in a patient with MR via transfemoral-transseptal access.
Study: NCT06664749

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three stair position pillow group
Description: Preterm infants were monitored with three stair position pillows.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Positioning material group
Description: Preterm infants were monitored with positioning material pillows.
Study: NCT05714579

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transcatheter Aortic Valve Implantation
Description: The TAVI procedure is performed transfemorally under local anesthesia most often, or more rarely under general anesthesia via the subclavian or transaortic route. Identification is carried out under fluoroscopy in the cardiac catheterization room. The crossing of the aortic valve allows the establishment of a guide at the bottom of the left ventricle. Aortic valve predilation can be performed. The tightness of the device is checked by an aortography. Sometimes, post-dilation of the implanted bioprosthesis proves necessary, particularly in the event of under-deployment or significant para-prosthetic leakage.~The duration of the intervention is approximately 1 hour.
Study: NCT05510323

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone
Description: RAS blockade as much as tolerated or allowed

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone plus Cyclophosphamide
Description: RAS blockade as much as tolerated or allowed
Study: NCT04382638

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: RCO group
Description: Patients in the experimental group will receive RCO fabrication with standard level of care for bracing, which consists of education on general exercises for spinal movement, strengthening, and balancing. These patients will attend study assessments at baseline, 3 months, 6 months, 12 months and every year until they reach skeletal maturity or if surgical intervention is required.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TLSO group
Description: Patients in the experimental group will receive TLSO fabrication with standard level of care for bracing, which consists of education on general exercises for spinal movement, strengthening, and balancing. These patients will attend study assessments at baseline, 3 months, 6 months, 12 months and every year until they reach skeletal maturity or if surgical intervention is required.
Study: NCT05857605

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise for Knee Osteoarthritis
Description: Standard physical therapy exercise instructions based on Arthritis Foundation guidelines for physical activity specific to individuals with knee osteoarthritis.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise for Knee Osteoarthritis
Description: Standard physical therapy exercise instructions based on Arthritis Foundation guidelines for physical activity specific to individuals with knee osteoarthritis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Compact seated elliptical exercise machine- Cubii JR-1
Description: Compact seated elliptical machine exerice program in conjunction with standard physical therapy exercise instructions based on Arthritis Foundation guidelines for physical activity specific to individuals with knee osteoarthritis.
Study: NCT05049161

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temelimab 18 mg/kg
Description: temelimab 18 mg/kg will be given as monthly (4-weekly) intravenous (IV) infusions over 48 weeks (12 administrations in total)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temelimab 36mg/kg
Description: temelimab 36 mg/kg will be given as monthly (4-weekly) intravenous (IV) infusions over 48 weeks (12 administrations in total)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temelimab 54 mg/kg
Description: temelimab 54 mg/kg will be given as monthly (4-weekly) intravenous (IV) infusions over 48 weeks (12 administrations in total)
Study: NCT04944485

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: (FIT SA F03, SHOFU, USA)
Description: Self adhesive giomer containing nanohybrid flowable composite

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: (Neo Spectra™ ST, Dentsply, Sirona, USA)
Description: Conventional technique using putty nanohybrid resin composite
Study: NCT06549439

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Electron FLASH radiotherapy
Description: A nominal electron energy of 9 MeV will be used for both Flash-RT and Conv-RT, which guarantees ≥ 90% dose coverage up to a depth of 2.8 cm. Shallower lesions will be treated with the same electron energy and with a bolus. In order to treat these patients, field sizes between 2x2cm2 and 10x10cm2 will be used, which can be delivered with sufficient flatness (\<5%) and symmetry (\<2%) by the FlashTrueBeam v2.7.5.
Study: NCT04936568

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Palliative Care Referral System - PCRS
Description: Implementation of a system to help oncologists to identify criteria for referring patients to specialized outpatient palliative care (Palliative Care Referral System - PCRS)
Study: NCT05477940

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Absorbable zinc alloy drug eluting coronary stent system
Description: Absorbable zinc alloy drug eluting coronary stent system (hereinafter referred to as stent system) consists of delivery system and drug stent (hereinafter referred to as stent) pressed on the balloon end of the delivery system
Study: NCT05831475

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intergenerational Virtual Paired Exercise
Description: Participants will be paired with someone older/ younger and will engage in exercise videos with the ability to simultaneously video chat with their partner while exercising. Participants will log on with their partner twice a week for 8 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Virtual Paired Exercise
Description: Participants will be paired with someone of the same age group and will engage in exercise videos with the ability to simultaneously video chat with their partner while exercising. Participants will log on with their partner twice a week for 8 weeks.
Study: NCT06642662

Intervention type: DIAGNOSTIC_TEST
Intervention: Somascan 5.0
Description: This observational study will test patient plasma using the SomaScan platform, a highly multiplexed proteomic tool that uses SOMAmers (Slow Off-rate Modified Aptamers) to bind with high specificity and affinity to preselected proteins to quantify levels. SomaScan v5.0 quantifies 10,778 clinically relevant human proteins, with several thousand proteins linked to inflammation and immune system functions, across a wide range of concentrations (\>10 logs) with high sensitivity (\<1 pg/mL) and reproducibility (median coefficient of variation \< 5%). Individual protein concentrations are transformed into a corresponding SOMAmer concentration and quantified using a DNA microarray read-out.

Intervention type: DIAGNOSTIC_TEST
Intervention: Somascan 5.0
Description: This observational study will test patient plasma using the SomaScan platform, a highly multiplexed proteomic tool that uses SOMAmers (Slow Off-rate Modified Aptamers) to bind with high specificity and affinity to preselected proteins to quantify levels. SomaScan v5.0 quantifies 10,778 clinically relevant human proteins, with several thousand proteins linked to inflammation and immune system functions, across a wide range of concentrations (\>10 logs) with high sensitivity (\<1 pg/mL) and reproducibility (median coefficient of variation \< 5%). Individual protein concentrations are transformed into a corresponding SOMAmer concentration and quantified using a DNA microarray read-out.

Intervention type: DIAGNOSTIC_TEST
Intervention: Somascan 5.0
Description: This observational study will test patient plasma using the SomaScan platform, a highly multiplexed proteomic tool that uses SOMAmers (Slow Off-rate Modified Aptamers) to bind with high specificity and affinity to preselected proteins to quantify levels. SomaScan v5.0 quantifies 10,778 clinically relevant human proteins, with several thousand proteins linked to inflammation and immune system functions, across a wide range of concentrations (\>10 logs) with high sensitivity (\<1 pg/mL) and reproducibility (median coefficient of variation \< 5%). Individual protein concentrations are transformed into a corresponding SOMAmer concentration and quantified using a DNA microarray read-out.
Study: NCT05636475

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual hand massage after laparoscopic cholecystectomy surgery
Description: Manual hand massage is applied to a group of patients at 0, 4 and 8 hours after the patient returns from laparoscopic cholecystectomy surgery. It is applied to each hand for ten minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Machine-based hand massage after laparoscopic cholecystectomy surgery
Description: Machine-based hand massage is applied to a group of patients at 0, 4 and 8 hours after the patient returns from laparoscopic cholecystectomy surgery. It is applied to each hand for ten minutes.
Study: NCT06319599

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine therapy
Description: During the treatment, All the participants are provided with the routine therapy, which included routine rehabilitation, cognitive training.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Routine therapy
Description: During the treatment, All the participants are provided with the routine therapy, which included routine rehabilitation, cognitive training.
Study: NCT05610215

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hybrid ablation
Description: simultaneous thoracoscopic epicardial and catheter endocardial ablation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: catheter ablation
Description: catheter endocardial ablation