TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04539808

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan Potassium
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Given IV

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Undergo short-course or long-course RT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resection
Description: Undergo surgical resection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diagnostic Imaging
Description: Undergo diagnostic imaging

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study: NCT06404476

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: saliva obtaining
Description: The patient was asked to sit upright and tilt his/her head forward to collect saliva samples. İn this way, unstimulated saliva was allowed to accumulate in the floor of the mouth. The accumulated saliva was collected in a sterile container. It was then transferred to a propylene tube. The tubes were centrifuged and the clear part at the top of the tube was taken with a sterile syringe and transferred to a different propylene tube with 0.5 ml in each tube. Tubes were stored at -80ºC until the day of analysis.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: saliva obtaining
Description: The patient was asked to sit upright and tilt his/her head forward to collect saliva samples. İn this way, unstimulated saliva was allowed to accumulate in the floor of the mouth. The accumulated saliva was collected in a sterile container. It was then transferred to a propylene tube. The tubes were centrifuged and the clear part at the top of the tube was taken with a sterile syringe and transferred to a different propylene tube with 0.5 ml in each tube. Tubes were stored at -80ºC until the day of analysis.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: saliva obtaining
Description: The patient was asked to sit upright and tilt his/her head forward to collect saliva samples. İn this way, unstimulated saliva was allowed to accumulate in the floor of the mouth. The accumulated saliva was collected in a sterile container. It was then transferred to a propylene tube. The tubes were centrifuged and the clear part at the top of the tube was taken with a sterile syringe and transferred to a different propylene tube with 0.5 ml in each tube. Tubes were stored at -80ºC until the day of analysis.
Study: NCT06301945

Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial Intelligence Diagnostics
Description: AI Diagnostics uses advanced algorithms for precise histological image analysis to help diagnose disease, including subtype.

Intervention type: DIAGNOSTIC_TEST
Intervention: Recurrence Prediction Tool
Description: This AI tool evaluates thymic tumour data and other clinical data and calculates the risk of recurrence, with the aim of analysing whether there is an association with specific subtypes of thymic epithelial tumours and clinical data.
Study: NCT06327997

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Fast CAR T cells
Description: This study designed three dose groups, each with a dosage of 5.0 × 10\^5/kg、1.0×10\^6/kg、5.0×10\^6/kg
Study: NCT05770206

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03
Description: Subjects in the experimental group will receive treatment by using Hydrogen-Oxygen Generator with Nebulizer (manufactured by Shanghai Asclepius Meditec Co., Ltd., flow rate: 3L/min) combined with conventional basic supportive treatment (symptomatic support treatment determined by the investigator based on the condition of the subjects);

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: OLO-1 Medical Molecular Sieve Oxygen Generator
Description: subjects in the control group will receive treatment by using Medical Molecular Sieve Oxygen Generator (manufactured by Shanghai Ouliang Medical Devices Co., Ltd., flow rate: 3L/min, provided by the sponsor) combined with conventional basic supportive treatment (same with that in the test group).
Study: NCT05151016

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mifepristone
Description: Mifepristone tablets, 10mg, 1 tablet daily, taken orally (beginning on the third day of Menstruation) for 24 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triptorelin Acetate
Description: dafinil, 3.75 mg, first injection on the third day of menstruation, followed by intramuscular injection every 28 days for 24 weeks.
Study: NCT05500261

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: intranasal administration of dexmedetomidine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: intranasal administration of dexmedetomidine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: intranasal administration of dexmedetomidine
Study: NCT04173169

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Elagolix 200 MG
Description: Elagolix tablet

Intervention type: OTHER
Group type: OTHER
Intervention: Placebo or SOC IVF
Description: Sugar pill manufactured to mimic Elagolix 200mg
Study: NCT03883217

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PDVibe2
Description: The PDVibe2 is owned by Resonate Forward, LLC and will be loaned to Virginia Commonwealth University (VCU) for this project. The device is non-invasive, lightweight, untethered, contains a rechargeable battery, and is worn on both feet and ankles. PDVibe2 delivers vibration when activated by an easy to access switch on the device or by remote. The internal circuitry has been miniaturized, is encased in a small box, and is attached to the ankle using a soft flexible band.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PDVibe2
Description: The PDVibe2 is owned by Resonate Forward, LLC and will be loaned to Virginia Commonwealth University (VCU) for this project. The device is non-invasive, lightweight, untethered, contains a rechargeable battery, and is worn on both feet and ankles. PDVibe2 delivers vibration when activated by an easy to access switch on the device or by remote. The internal circuitry has been miniaturized, is encased in a small box, and is attached to the ankle using a soft flexible band.
Study: NCT06381310

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: asus-handheld-ultrasound LU710L
Description: Ultrasound-guided group:The nurse uses ultrasound-guide injection. control group: After physical assessment by the nurse, the injection will be carried out according to the conventional injection plan.
Study: NCT05136261

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ceradan ® Advanced Cream
Description: Ceradan ® Advanced Cream

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Basic cream
Description: Basic cream
Study: NCT05889598

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ballistic Resistance Lower Body Strength Training
Description: The exercise programme involves two supervised sessions per week at University. Each session will involve 30-40 minutes of exercise, comprising warm-up , two main exercises: a hack squat and calf raise using a hack squat machine, and core exercises. After a warm-up period involving 5 minutes cycling and one set of 5 conventional repetitions at 40%1RM, the ballistic training group will complete eccentric phase hack squat exercise in approximately 3 seconds and the concentric phase as fast as possible with throwing type contractions. If participants can, participants will be allowed to take off in the concentric phase. To maintain high velocity in this group, lower loads will be used compared to the conventional group. The load will be decided according to regular maximal muscular strength test (1RM) to use of the correct weight for training (in proportion to the strength). Participants will start off using light weights and these will increase as participants become stronger.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Resistance Lower Body Strength Training
Description: The exercise programme involves two supervised sessions per week at Loughborough University. Each session will involve 30-40 minutes of exercise, comprising warm-up , two main exercises: a hack squat and calf raise using a hack squat machine, and core exercises. After a warm-up period involving 5 minutes cycling and one set of 5 conventional repetitions at 40% of 1RM, the conventional training group will complete eccentric and concentric phases of hack squatting exercises for approximately 3 seconds each, with appropriate breathing techniques. The load will be decided according to regular maximal muscular strength test (1RM) to use of the correct weight for training (in proportion to the strength). Participants will start off using light weights and these will increase as participants become stronger.
Study: NCT05707117

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tendon neuroplastic training (TNT)
Description: Subjects will attend physical therapy for three non-consecutive days per week for a total 4 consecutive weeks. Exercise would involve isolated flexion, extension with a dumbbell. This exercise would be paced with external audio/visual cue on smart phone using proMetronome app. Patients will listen to the sound and track the movement of metronome with the eyes. Pace of metronome will be set at 20 beats per minute such that each beat will be 3 sec apart. This will allow a 3sec concentric and 3 sec eccentric phases.4 sets of 8 repetitions would be completed with a 2-minute rest between each set. Exercise will begin with 3 pounds weight, but it would be made sure that this wouldn't cause pain during exercise (more than 5/10), gradual progression in weight to 5 pounds after 2nd weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: group B Conventional treatment
Description: Subjects assigned to this group will undergo static stretching of Extensor carpi radialis brevis and myofascial release for 4 weeks, 3 sessions a week. Myofascial release technique will be applied for 5 minutes and 2 reptations per session
Study: NCT04871672

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home Exercise program
Description: home exercise
Study: NCT06158113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baricitinib 4 milligram Oral Tablet
Description: 4 milligrams once daily
Study: NCT04712552

Intervention type: PROCEDURE
Intervention: deep brain stimulation
Description: On the day of surgery, under general anesthesia, a Fischer ZD frame will be attached to the skull. A T1-weighted 3D MRI with gadolinium will be performed.~Investigators will plan on this MRI, anatomical targets and deep brain trajectories using the NeuroInspire surgical planning software.~The patient will be attached to the base of the robot through the frame. Registration will be performed using the Neurolocate method after the acquisition of 3D CT images using the O-arm. The Neurolocate recording is based on radiographic images.The 3D MRI will be merged with the 3D tomography images taken with the O-arm to co-register the trajectories planned on the MRI in the robot space The surgical procedure will be performed as usual by milling the bone at the entry point and inserting under robotic guidance an electrode through a guide tube to the intended target.
Study: NCT01671631

Intervention type: OTHER
Intervention: Measurement of intracoronary pressure
Study: NCT05105867

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-CD19 Universal CAR-T Cells injection
Description: Anti-CD19 Universal CAR-T Cells injection will be administered by vein after lymphodepletion.
Study: NCT05080374

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation + exercise program
Description: high-speed, low-amplitude spinal manipulation plus a trunk exercise program

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal manipulation + Kinesiotaping
Description: high-speed, low-amplitude spinal manipulation plus elastic bandage (Kinesiotaping) application to the trunk area

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: spinal manipulation + respiratory exercise
Description: high-speed, low-amplitude spinal manipulation plus a breathing exercise program for the diaphragmatic muscles
Study: NCT05964296

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The MAURISSE application use
Description: * Exchanges with the care team via the messaging system,~* Postponement of consumption,~* Monitoring of consumption,~* Access to information on the To Do List,~* Access to personal content to help with management (Socio-professional situation, type of life, personal history..).~* Postponement of a feeling of boredom,~* Access to proposals to fight against this feeling.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: The usual care within the center will consist of appointments with doctors; regular follow-up meetings with nurses, psychologists, social workers, therapeutic groups depending on the evaluation.
Study: NCT05196958

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GLP1 analogues
Description: This cohort study has 2 phases: an observation phase to collect all initial clinical and biological parameters and an intervention phase (prescription of GLP1 analogues) of 6 months including a visit at 3 and 6 months.
Study: NCT06372899

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-cigarettes
Description: Participants randomized to ECIGS are instructed to switch from smoking combustible cigarettes to using e-cigarettes for 6 weeks. They will be provided with an e-cigarette device and nicotine pods.
Study: NCT06036316

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Language assessment
Description: The proposed speech and language therapy assessment will consist of a battery of standardized tests that speech and language therapists can use to assess the language skills in reception and expression of adult patients.~Concerning the assessment of the interactions between working memory and semantic abilities, a complete protocol has been developed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Language assessment
Description: The proposed speech and language therapy assessment will consist of a battery of standardized tests that speech and language therapists can use to assess the language skills in reception and expression of adult patients.~Concerning the assessment of the interactions between working memory and semantic abilities, a complete protocol has been developed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Language assessment
Description: The proposed speech and language therapy assessment will consist of a battery of standardized tests that speech and language therapists can use to assess the language skills in reception and expression of adult patients.~Concerning the assessment of the interactions between working memory and semantic abilities, a complete protocol has been developed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TLC - Scale for the Assessment of Thought, Language, and Communication
Description: This scale is frequently used in psychiatry and is used to measure formal thought disorders in patients suffering from psychosis. As part of this study, it will be intended for patients suffering from schizophrenia

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MINI - Mini International Neuropsychiatric Interview
Description: This scale corresponds to a rapid assessment of the psychiatric and psychological state of patients. It helps detect any psychiatric disorders. Here, it will be offered to volunteers who are part of the control group.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CAST - Cannabis Abuse Screening Test
Description: The purpose of this questionnaire is to approximate participants' cannabis consumption and to assess any disorders associated with cannabis consumption. It will be offered to all participants, patients and healthy controls

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CAST - Cannabis Abuse Screening Test
Description: The purpose of this questionnaire is to approximate participants' cannabis consumption and to assess any disorders associated with cannabis consumption. It will be offered to all participants, patients and healthy controls

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CAST - Cannabis Abuse Screening Test
Description: The purpose of this questionnaire is to approximate participants' cannabis consumption and to assess any disorders associated with cannabis consumption. It will be offered to all participants, patients and healthy controls
Study: NCT05286866

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dental implant bed preparation
Description: Drilling an osteotomy for placement of a dental implant

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dental implant bed preparation
Description: Drilling an osteotomy for placement of a dental implant
Study: NCT05761665

Intervention type: OTHER
Intervention: Evaluation
Description: Kinesiophobia=Tampa scale Balance=Berg Balance Scale Falling=The Fall Activity Scale( Tinetti) Walking speed=Timed Get Up and Walk Test ,Two-Minute Walking Test Fragility=Frail Fragility Questionnaire, Clinical Fragility Scale

Intervention type: OTHER
Intervention: Evaluation
Description: Kinesiophobia=Tampa scale Balance=Berg Balance Scale Falling=The Fall Activity Scale( Tinetti) Walking speed=Timed Get Up and Walk Test ,Two-Minute Walking Test Fragility=Frail Fragility Questionnaire, Clinical Fragility Scale

Intervention type: OTHER
Intervention: Evaluation
Description: Kinesiophobia=Tampa scale Balance=Berg Balance Scale Falling=The Fall Activity Scale( Tinetti) Walking speed=Timed Get Up and Walk Test ,Two-Minute Walking Test Fragility=Frail Fragility Questionnaire, Clinical Fragility Scale
Study: NCT06372899

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral nicotine pouches
Description: Participants randomized to ONPS are instructed to switch from smoking combustible cigarettes to using nicotine pouches for 6 weeks. They will be provided with nicotine pouches.
Study: NCT06253962

Intervention type: OTHER
Intervention: coronary agiongraphy
Description: severity of coronary atherosclerosis

Intervention type: OTHER
Intervention: coronary agiongraphy
Description: severity of coronary atherosclerosis
Study: NCT05460156

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bridges Self-management Support
Description: Self-management support intervention tailored for people with neuromuscular diseases
Study: NCT05900973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Darolutamide Oral Tablet [Nubeqa]
Description: Oral use of Darolutamide as an Inducer of Increased Expression of Prostate-specific membrane antigen (PSMA) in patients with Localized prostate cancer
Study: NCT04915417

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Ablative Body Radiotherapy (SABR)
Description: Patients will receive 27-30 Gy in 3 fractions to the planning target volume (PTV) with a simultaneous in-field boost to the metabolically active areas of the gross tumor volume (GTV) to a maximum of 45 Gy. Patients will be treated every other day.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Ablative Body Radiotherapy (SABR)
Description: Patients will receive 27-30 Gy in 3 fractions to the planning target volume (PTV) with a simultaneous in-field boost to the metabolically active areas of the gross tumor volume (GTV) to a maximum of 45 Gy. Patients will be treated every other day.
Study: NCT05434520

Intervention type: PROCEDURE
Intervention: Preoperative biliary drainage (ERC og PTC-aided)
Description: Placement of biliary stent (plastic, covered SEMS, uncovered SEMS) endoscopic by ERC or placement of plastic catheter by PTC
Study: NCT05309109

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodialysis sessions
Description: Patients will receive thrice weekly 4 hours hemodialysis sessions during 12 months.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodialysis sessions
Description: Patients will receive thrice weekly 4 hours hemodialysis sessions during 12 months.
Study: NCT05110456

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telephone support
Description: Participants will receive 10 telephone counseling calls by trained coaches: 9 during pregnancy (one call/week) and 1 at 6 weeks postpartum. We have included individual telephone calls by a trained coaches aimed to :~1. encourage the use of online material;~2. identify strategies for overcoming obstacles;~3. help apply content to real-life settings; and~4. underscore the participants' success in using effective coping strategies
Study: NCT06435533

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low energy argonplasma coagulation
Description: see above
Study: NCT05324124

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selpercatinib
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selpercatinib
Description: Administered orally.
Study: NCT05408026

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab (and hyaluronidase) will be given over 3-5 minutes subcutaneously (under the skin) in the clinic at alternating left/right abdominal sites. Patient will take dexamethasone orally (by mouth) either before coming to clinic or in clinic, before other medications.~Only for the first cycle, patient will receive on Day 1 daratumumab (which is mixed with a compound called hyaluronidase) and dexamethasone, 1 day before patient start the other 2 medications.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: On day 2 of cycle 1, patient will start the other medications and will therefore receive bortezomib administered subcutaneously (SC) over 3-5 minutes and dexamethasone given orally (by mouth), either before coming to clinic or in clinic, before bortezomib. Patient will also start pomalidomide on the same day, which patient will take that evening at home and every evening for 21 days.
Study: NCT06515262

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-BCMA-GPRC5D CAR-T cells infusion
Description: Subiects who meet the enrollment conditions will receive intravenous infusion of anti-BCMA-GPRC5D CAR-T Cells after lymphodepleting therapy.
Study: NCT06241625

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Virtual Reality (VR) Contrast Function Test
Description: Patients perform a new Virtual Reality (VR) Contrast Function Test