TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05886621

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smiling instead of Smoking - HIV
Description: Participants will be onboarded to the smartphone app Smiling instead of Smoking - HIV (SiS-H) and will be asked to complete the integrated SiS-H program while they quit smoking. The integrated SiS-H treatment consists of: (1) face-to-face onboarding to the SiS-H app, (2) one face-to-face session discussing app usage and antiretroviral therapy (ART) adherence (Life Steps), with direct linkage to tools in the app supporting ART adherence, and (3) an 8-week course of the SiS-H app. The SiS-H app is a smoking cessation app that uses a positive psychology framework in conjunction with with the US Clinical Practice Guidelines for smoking cessation to guide participants through the process of quitting smoking.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: QuitGuide
Description: Participants will be onboarded to the NCI smartphone app QuitGuide(QG) and will be asked to use it for 8 weeks to support them in quitting smoking. The QuitGuide app follows the US Clinical Practice Guidelines. The app is freely available on NCI's Smokefree.gov website, which is a recommended resource for treating smokers in the healthcare setting. The QuitGuide app is frequently used as a comparison app in smartphone app smoking cessation studies. It asks participants to set a quit day, track their mood and cravings, and log their cigarettes. It provides app users with guidance on quitting (i.e., Learn to Quit information), offers strategies to counter smoking triggers, and allows users to set reminders to stay smoke free (time and location based).
Study: NCT05396547

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Treated with Ledinbio device
Description: Treated with Ledinbio device
Study: NCT05585905

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: The VR system will be worn for approximately 5-10 minutes during dental sealant application

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Basic Behavior Guidance Techniques
Description: Basic behavior guidance techniques will be used as a distraction technique when the VR system is not used during the dental sealant application
Study: NCT04900324

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MRI guidance
Description: Injections of botulinum toxin performed using MRI guidance

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound guidance
Description: Injections of botulinum toxin performed using ultrasound guidance
Study: NCT03651752

Intervention type: DRUG
Group type: OTHER
Intervention: Diphenylcyclopropenone (DPCP) Ointment
Description: All subjects will be administered a sensitization dose of 0.05 mL 0.4% DPCP ointment formulation topically in the inner aspect of the upper right arm at Day -16, and 0.05 mL of four concentrations (0.1, .05, 0.01, 0.005%), prepared through dilutions in the ointment vehicle, topically on the inner aspect of the left thigh at Day -2. The weakest strength that may cause a minimal reaction (DTH skin reaction score of 1+) after two days will be chosen, and 0.75-1 g of that concentration will be applied to the scalp starting at Week 1 and administered subsequently twice a week for 18 weeks
Study: NCT06142682

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cochlear Implant
Description: cochlear implantation with dexamethasone eluting electrode
Study: NCT04790916

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RO7049665
Description: RO7049665, subcutaneous injection, Q2W.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RO7049665
Description: RO7049665, subcutaneous injection, Q2W.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: RO7049665-matching placebo, subcutaneous injection, Q2W.
Study: NCT04733469

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimedia Psychoeducational Intervention
Description: The Multimedia Psychoeducational Intervention includes a multimedia educational video plus additional resources to reinforce the video content. The Multimedia Psychoeducational Intervention includes the following:~* A multimedia educational video about palliative care that is individually tailored to each patient's level of education and health literacy~* Take-home and online copies of the video for repeat viewing~* A video summary~* A question prompt list patients can use to ask clinicians more questions about palliative care~* Contact information and brochures for local palliative care programs

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Enhanced Usual Care
Description: Enhanced Usual Care refers to usual care plus minor enhancement to improve quality and standardization. Enhanced Usual Care includes the following:~* Usual care~* A packet of flyers and handouts with general information on psychosocial oncology services derived from the American Society of Clinical Oncology (ASCO), Center to Advance Palliative Care (CAPC), and American Cancer Society (ACS)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced Usual Care
Description: Enhanced Usual Care refers to usual care plus minor enhancement to improve quality and standardization. Enhanced Usual Care includes the following:~* Usual care~* A packet of flyers and handouts with general information on psychosocial oncology services derived from the American Society of Clinical Oncology (ASCO), Center to Advance Palliative Care (CAPC), and American Cancer Society (ACS)
Study: NCT04833582

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZN-c3
Description: ZN-c3 is an investigational drug.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine is an approved drug
Study: NCT04806685

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep education
Description: Medical nutrition therapy plus behavior-based sleep education intervention

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Diet only
Description: No sleep education
Study: NCT06274736

Intervention type: DEVICE
Intervention: Motiva Sizer
Description: No intervention will be made,
Study: NCT03831152

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ADV7103
Description: Single group assignment
Study: NCT05403346

Intervention type: DEVICE
Intervention: CoviDx™ Covid-19 Antigen Self-Test
Description: All patients will self-collect a mid-turbinate nasal swab for CoviDx™ Covid-19 Antigen self-testing
Study: NCT05777499

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music Therapy
Description: Music Therapy will comprise individual and group sessions 20-45 minutes. Participants usually have 1-2 individual sessions, and 1 group session/week. Group sessions include 2-6 participants. On average, participants receive an average 1 hour 30 minutes Music Therapy/week, timetabled when they would not otherwise be undergoing any therapy sessions. The Music Therapist will use the Nordoff Robbins approach and work flexibly as a musician. Techniques include (but are not limited to) empathic listening, musically matching, turn taking and sequencing, call and response. Sessions may also involve songwriting, singing familiar songs, listening to, sharing and discussing music, developing specific musical skills of interest to the participant, structured musical games and activities, joint working with other members of the therapy team in sessions focused on functional development and communication skills.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Therapy
Description: Control Therapy sessions will be carried out by a member of the clinical team, matched in duration and number to Music Therapy sessions as closely as possible. Participants will usually have 1-2 individual sessions and 1 group session/week. Group sessions include 2-6 participants. The Control Therapy intervention will continue throughout participant's rehabilitation program until participants have completed a total of 15 hours intervention, which will usually take 10 weeks to complete. The content of sessions is designed to reflect 'usual care' however control therapy sessions will not include access to specific specialist equipment such as MOTOmed, therabike or neuro-muscular electrical stimulation, to ensure the control group does not get additional specialist intervention beyond usual care. Content of control therapy sessions will therefore be restricted to the following five domains: gaming, education, mindfulness, current affairs discussions, and passive and dynamic stretching.
Study: NCT05739721

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Attractiveness
Description: Visual attractiveness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Attractiveness
Description: Visual attractiveness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Attractiveness
Description: Visual attractiveness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Attractiveness
Description: Visual attractiveness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Esteem
Description: Self Esteem scale

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Esteem
Description: Self Esteem scale

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Esteem
Description: Self Esteem scale

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Esteem
Description: Self Esteem scale

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trustworthiness
Description: Trustworthiness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trustworthiness
Description: Trustworthiness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trustworthiness
Description: Trustworthiness scale 0-7

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trustworthiness
Description: Trustworthiness scale 0-7
Study: NCT04511182

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise-based cardiac rehabilitation
Description: Exercise program is based on aerobic exercise and supplemented by strength training following the principle of gradual improvement. The type of exercise, such as walking, jogging, cycling, and the intensity of exercise which is recommended to use a cardiotach or pedometer to detect, are both defined by the results of CPET, such as METs value. Participators must be prepared for about 5-10 minutes to warm up and recover before and after exercise. 30-50 minutes a day, 5 days a week, with a total exercise time of not less than 150 minutes per week. It can be carried out in different stages according to the physical condition. After 1-3 months, the exercise prescription will be re-adjusted according to the results of reexamination.~All patients will undergo Cardiopulmonary Exercise Test, SF-36, echocardiography and laboratory examination prior to initiation of the trial, and which will be checked again after 3 months, and 6 months.
Study: NCT04950504

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CNP-201
Description: CNP-201 is comprised of purified peanut extract (PPE) drug substance dispersed within a negatively charged polymer matrix of poly (lactic-co-glycolic acid) (PLGA) particles at a target concentration of \~5 μg of PPE per mg of PLGA.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CNP-201
Description: CNP-201 is comprised of purified peanut extract (PPE) drug substance dispersed within a negatively charged polymer matrix of poly (lactic-co-glycolic acid) (PLGA) particles at a target concentration of \~5 μg of PPE per mg of PLGA.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CNP-201
Description: CNP-201 is comprised of purified peanut extract (PPE) drug substance dispersed within a negatively charged polymer matrix of poly (lactic-co-glycolic acid) (PLGA) particles at a target concentration of \~5 μg of PPE per mg of PLGA.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: CNP-201 Placebo
Study: NCT06074965

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medtronic Extended Infusion Set
Description: Each subject will be given 2 types of infusion sets to wear and change sets per label use (3 days for Medtronic Quick-set™ and 7 days for Medtronic Extended).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medtronic Extended Infusion Set
Description: Each subject will be given 2 types of infusion sets to wear and change sets per label use (3 days for Medtronic Quick-set™ and 7 days for Medtronic Extended).
Study: NCT05251662

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 200mg IV d1 Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 200mg IV d1 Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI305
Description: 7.5mg/kg IV d1 Q3W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: GEMOX
Description: Oxaliplatin 100mg/m2 IV d1 Q3W+ gemcitabine 1000mg/m2 IV d1/8 Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GEMOX
Description: Oxaliplatin 100mg/m2 IV d1 Q3W+ gemcitabine 1000mg/m2 IV d1/8 Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GEMOX
Description: Oxaliplatin 100mg/m2 IV d1 Q3W+ gemcitabine 1000mg/m2 IV d1/8 Q3W
Study: NCT06081504

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wii fit exercises program
Description: Wii fit exercises for balance training and lower limb strengthening for 30 minutes. In addition to warming up and cooling down, 10 minutes each in the form of a range of motion exercises and stretching.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercises program
Description: Selected pilates exercises for balance training and lower limb strengthening: Articulating bridge, Spine stretch, Single leg stretch, Double leg stretch, Criss-cross, One leg kick, Side kick, Hip twist, and Standing footwork for 30 minutes, 10 repetitions each. In addition to the warming up and the cooling down exercises before and after the pilates exercises, 10 minutes each in the form of a range of motion exercises and stretching, and deep friction massage for scar management.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard physical therapy program
Description: All patients will receive the standard physical therapy program consisting of 45 minutes per session of a supervised and individualized exercise program for three sessions per week for eight weeks which will include: Stretching exercises for lower limb muscles, each stretch will be maintained for 45 seconds, 3 repetitions, strengthening exercises for lower limb muscles starting from 50 to 60% of 1 repetition maximum and the intensity will be increased gradually until 80 to 85 % through the treatments weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard physical therapy program
Description: All patients will receive the standard physical therapy program consisting of 45 minutes per session of a supervised and individualized exercise program for three sessions per week for eight weeks which will include: Stretching exercises for lower limb muscles, each stretch will be maintained for 45 seconds, 3 repetitions, strengthening exercises for lower limb muscles starting from 50 to 60% of 1 repetition maximum and the intensity will be increased gradually until 80 to 85 % through the treatments weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard physical therapy program
Description: All patients will receive the standard physical therapy program consisting of 45 minutes per session of a supervised and individualized exercise program for three sessions per week for eight weeks which will include: Stretching exercises for lower limb muscles, each stretch will be maintained for 45 seconds, 3 repetitions, strengthening exercises for lower limb muscles starting from 50 to 60% of 1 repetition maximum and the intensity will be increased gradually until 80 to 85 % through the treatments weeks.
Study: NCT06355193

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Langenlianqiao
Description: The data of patients with COVID-19 mild disease treated in our Hospital from November to December 2022 were collected, and the patients were divided into 100 cases of langenlianqiao(LGLQ) treatment group, 100 cases of LianhuaQingWen(LHQW) treatment group, and 53 cases of placebo control group according to the treatments they received, and the proportion of occurrence of major clinical symptoms, the time of symptom disappearance, and the number of days in hospitalization, and the duration of infection were compared among the three groups.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LianhuaQingWen
Description: The data of patients with COVID-19 mild disease treated in our Hospital from November to December 2022 were collected, and the patients were divided into 100 cases of langenlianqiao(LGLQ) treatment group, 100 cases of LianhuaQingWen(LHQW) treatment group, and 53 cases of placebo control group according to the treatments they received, and the proportion of occurrence of major clinical symptoms, the time of symptom disappearance, and the number of days in hospitalization, and the duration of infection were compared among the three groups.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo control group
Description: placebo control group
Study: NCT06098456

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EGCG, FA, HA, B12
Description: Epigallocatechin gallate 200mg, Hyaluronic acid 50mg, Vitamin B12 1mg, Folic acid 400mcg
Study: NCT05353933

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thread embedding acupuncture
Description: Thread embedding acupuncture (TEA) that use chromic catgut thread with 3/0 size with 1 centimeter long for each acupoint (TRUSTIGUT® (C), CPT Sutures Co., Ltd, Ho Chi Minh, Vietnam). Every 2 weeks in 4 weeks (twice), 13 acupoints will be embedded including Xiawan (CV-10), Zhongwan (CV-12), Shangwan (CV-13) and Zusanli (ST-36), Neiguan (PC-6), Geshu (BL-17), Ganshu (BL-18), Pishu (BL-20) in both sides of the body.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pantoprazole 40mg
Description: Oral pantoprazole 40 mg capsules (Pantostad 40 CAP, Stellapharm J.V. Co., Ltd, Binh Duong, Vietnam) thirty minutes to one hour before the first meal once daily for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pantoprazole 40mg
Description: Oral pantoprazole 40 mg capsules (Pantostad 40 CAP, Stellapharm J.V. Co., Ltd, Binh Duong, Vietnam) thirty minutes to one hour before the first meal once daily for 4 weeks.
Study: NCT05613374

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The C-Mill virtual reality treadmill
Description: The C-Mill treadmill is an innovative device used for the training of impaired gait and balance. The C-Mill is an instrumented treadmill with interactive virtual reality games and applications.The instrument is supplied with a safety frame, body weight support, treadmill force plates, treadmill belt, adjustable handrails, cameras, user operating system, interactive visual screen and augmented reality projection.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy Program
Description: The Conventional Physical Therapy Program include the following:~* Postural reactions exercises. (using balance board, balance beam, and manual balance perturbations)~* Indoor open environment gait training exercises (over ground gait training exercises.). (using obstacles,cones , stepper, balance board , and uneven surfaces) (either between or outside the parallel bar)
Study: NCT05502549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CB03-154
Description: CB03-154 tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily.
Study: NCT05189717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-8080 tablets、SHR 6390 tablets、Abemaciclib、Everolimus
Description: During HRS-8080 monotherapy period, the dose of HRS-8080 would be increasing. In the combination therapy period, HRS-8080 will be administered at flat dose of RP2D-1 and RP2D.
Study: NCT04624126

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D-Erect
Description: 3D-printed erectile device for intercourse
Study: NCT06472609

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: enhanced interactive education
Description: The present study is a prospective randomized open-label study. Patients with diabetes mellitus who have HbA1c% more than 9% during the recent 1 year are enrolled. The intervention group receives, besides routine medical control of diabetes,enhanced interactive education program through weekly phone call for 12 weeks.
Study: NCT05625126

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rumination Intervention for individuals with PTSD
Description: The intervention utilises evidence-based cognitive behavioural therapy (CBT) techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rumination Intervention for individuals with PTSD
Description: The intervention utilises evidence-based cognitive behavioural therapy (CBT) techniques.
Study: NCT05184088

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]florbetaben
Description: All enrolled patients will undergo \[18F\]florbetaben PET imaging.
Study: NCT06237686

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CP363
Description: All subjects will test both Test product A and B, with a minimum of 7 days apart. In total, each subject will be enrolled in the investigation for 8 days +3 days.