TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06250595

Intervention type: OTHER
Intervention: Collection of clinical and laboratory data from EHR.
Description: Observational sutdy

Intervention type: OTHER
Intervention: Collection of clinical and laboratory data from EHR.
Description: Observational sutdy

Intervention type: OTHER
Intervention: Collection of clinical and laboratory data from EHR.
Description: Observational sutdy

Intervention type: OTHER
Intervention: Collection of clinical and laboratory data from EHR.
Description: Observational sutdy

Intervention type: OTHER
Intervention: Collection of clinical and laboratory data from EHR.
Description: Observational sutdy

Intervention type: OTHER
Intervention: Collection of clinical and laboratory data from EHR.
Description: Observational sutdy
Study: NCT05172375

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Shared Care Model
Description: The Shared Care model consists of the following key elements: Shared care is a collaboration between general practice and mental health services and enables a 'best of both worlds' scenario with the opportunity to provide holistic care of high quality to support the recovery process of people with mental health difficulties.
Study: NCT05425667

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality walking training
Description: The sensory integration training of this project will combine virtual reality technology and balance interference treadmill, and manipulate vision, vestibular sense and proprioceptive systems as the main training goals. It is expected to train twice a week for 1 hour, for a total of 6 weeks of training , in order to improve the balance and walking ability of patients with lumbar stenosis and neurological claudication, and to promote the ability of subjects to transfer the effect to daily life after training.
Study: NCT05889338

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: adalimumab and methotrexate
Description: Adult patients (\> 18 years) with severe psoriasis who will start treatment with either adalimumab or methotrexate

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: adalimumab and methotrexate
Description: Adult patients (\> 18 years) with severe psoriasis who will start treatment with either adalimumab or methotrexate
Study: NCT05368623

Intervention type: DIAGNOSTIC_TEST
Intervention: Color fundus photograph
Description: Subjects will undergo color fundus photography before and after pharmacological dilation of pupils.

Intervention type: DIAGNOSTIC_TEST
Intervention: Optical Coherence Tomography (OCT) of the retina
Description: Subjects will undergo OCT of the retina after pharmacological dilation of pupils.

Intervention type: DRUG
Intervention: Mydriatic Agent
Description: Pharmacological dilation of pupils will be done by instilling mydriatic agent in eyes of Subjects
Study: NCT05592509

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Ozonized vegetable oil with vitamines
Description: description: A single capsule is composed by ozonized vegetable oil (75 mg), vitamin K2 (20 mcg), vitamin B9 (130 mcg). The posology is three capsules/day.~The time of administration is two months.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ozonized vegetable oil with vitamines
Description: description: A single capsule is composed by ozonized vegetable oil (75 mg), vitamin K2 (20 mcg), vitamin B9 (130 mcg). The posology is three capsules/day.~The time of administration is two months.
Study: NCT05219227

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: laser acupuncture and abdominal exercises
Description: laser acupuncture on certain point on the abdomen The following abdominal acupuncture points were irradiated: Cv 8 (Shenque), St 25 (Tianshu, bilateral), and Sp 15 (Daheng~, bilateral). The laser irradiations were applied directly to the skin of the points with a perpendicular beam. 478 J/cm2~Abdominal exercises:~Types of abdominal exercises:~1. Static abdominal exercises:~2. Dynamic abdominal exercises:~   * Hip shrugging exercise from crook lying position:~  * Lateral flexion of the trunk from crook lying position:~  * Antero-posterior flexion of the trunk from crook lying position:

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: laser acupuncture and abdominal exercises
Description: laser acupuncture on certain point on the abdomen The following abdominal acupuncture points were irradiated: Cv 8 (Shenque), St 25 (Tianshu, bilateral), and Sp 15 (Daheng~, bilateral). The laser irradiations were applied directly to the skin of the points with a perpendicular beam. 478 J/cm2~Abdominal exercises:~Types of abdominal exercises:~1. Static abdominal exercises:~2. Dynamic abdominal exercises:~   * Hip shrugging exercise from crook lying position:~  * Lateral flexion of the trunk from crook lying position:~  * Antero-posterior flexion of the trunk from crook lying position:
Study: NCT04117165

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Biotherapy Prescription with SinnoTest® software
Description: The rheumatologist will use the SinnoTest® software to give the best biotherapy to the patient according to the results of the software.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Patient Current Care
Description: The rheumatologist will use the french guidelines of rheumatoid arthritis to choose the more adapted biotherapy treatment to the patient.
Study: NCT06093997

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage treatment
Description: The patient sits upright and the neck naturally relaxes. The doctor uses techniques such as pressing and kneading to relax the soft tissues of the neck, and massages points such as FengMen, FengChi, JingJiaji, JianJing,Tianzong and so on. The focus is on using muscle relaxation techniques around the soft tissues of spasms and pain areas to relax the patient's neck and shoulders. All procedures were performed from mild to severe, once a week for 15 minutes each time, for a total of 4 weeks of treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cupping
Description: Use a 4-5cm diameter suction cupping for cupping. The treatment area is coated with glycerol, and the cupping is aspirated and adsorbed on the skin. The cupping is slowly pushed along the patient's neck, along the urinary bladder channel of Foot-Taiyang and governor's meridians from top to bottom, repeating back and forth 9 times. Once a week, for a total of 4 weeks of treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bloodletting
Description: the doctor takes JianZhongShu, one on the left and one on the right, with a total of 2 acupoints. After disinfecting with 75% alcohol cotton balls, the patient is quickly pricked 5 times with a blood collection needle, and cupping is performed at the needle hole. After 5 minutes, remove the jar, wipe the blood clean, and disinfect the needle hole. Once a week, for a total of 4 weeks of treatment.
Study: NCT06547190

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High AGEs diet
Description: Participants sequentially consumed a diet that was high in AGEs and low in AGEs just be altering their cooking method. The High AGEs diet was cooked for example by baking and grilling.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High AGEs diet
Description: Participants sequentially consumed a diet that was high in AGEs and low in AGEs just be altering their cooking method. The High AGEs diet was cooked for example by baking and grilling.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low AGEs diet
Description: Participants sequentially consumed a diet that was high in AGEs and low in AGEs just be altering their cooking method. The low AGEs diet was cooked for example by steaming and boiling.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low AGEs diet
Description: Participants sequentially consumed a diet that was high in AGEs and low in AGEs just be altering their cooking method. The low AGEs diet was cooked for example by steaming and boiling.
Study: NCT05529511

Intervention type: OTHER
Intervention: Phase 1 - semi-structured interviews
Description: Semi-structured face-to-face or virtual interviews.

Intervention type: OTHER
Intervention: Phase 2 - consensus meeting
Description: Face-to-face or virtual meeting(s)
Study: NCT04878146

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sacro-spinous fixation
Description: Uterine cervix will be attached to the sacro-spinous ligament

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subtotal hysterectomy
Description: Done on both arms

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Subtotal hysterectomy
Description: Done on both arms

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sacrocolpopexy
Description: Uterine cervix is attached to sacral promontory with two synthetic meshes
Study: NCT05380635

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hypericin
Description: HyBryte is synthetic hypericin formulated as a 0.25% hypericin ointment.
Study: NCT03682042

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Umbilical Cord Milking
Description: At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 10-15 seconds.
Study: NCT06484218

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: conventional endodontic treatment
Description: The conventional access cavity was prepared under the microscope through the incisal edge as this approach facilitates straight-line access. A high-speed contra-angle handpiece, associated with a long surgical bur 010 (Meisinger, CO, USA), was used until the dentin was exposed, which is in general 3 to 4 millimeters from the incisal edge. Then, the ultrasonic tip ED5 (woodpecker-DTE, Guilin, China) was marked with a stopper according to the calcification level viewed on the preoperative CBCT and then used gently at the stopper level until the canal was found.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional endodontic treatment
Description: The conventional access cavity was prepared under the microscope through the incisal edge as this approach facilitates straight-line access. A high-speed contra-angle handpiece, associated with a long surgical bur 010 (Meisinger, CO, USA), was used until the dentin was exposed, which is in general 3 to 4 millimeters from the incisal edge. Then, the ultrasonic tip ED5 (woodpecker-DTE, Guilin, China) was marked with a stopper according to the calcification level viewed on the preoperative CBCT and then used gently at the stopper level until the canal was found.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Guided endodontic treatment
Description: In all cases, digital and clinical protocols were followed according to the method reported by Zehnder et al. and Connert et al. The guide was replaced, and the access cavity precisely drilled using the EG6 drill, mounted on a low-speed contra-angle handpiece. With every 3 mm of progression, the cavity was rinsed, and the head of the bur was cleaned until reaching the canal. The irrigation was done to avoid overheating the dentine and the accumulation of dentine debris

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Guided endodontic treatment
Description: In all cases, digital and clinical protocols were followed according to the method reported by Zehnder et al. and Connert et al. The guide was replaced, and the access cavity precisely drilled using the EG6 drill, mounted on a low-speed contra-angle handpiece. With every 3 mm of progression, the cavity was rinsed, and the head of the bur was cleaned until reaching the canal. The irrigation was done to avoid overheating the dentine and the accumulation of dentine debris
Study: NCT06256536

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR18
Description: 0.6 mg-30 mg

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: administered the same volume as GZR18
Study: NCT06009913

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: online teaching
Description: teaching of subject was done using online system only

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: In class teaching
Description: subjects were explained in normal class room
Study: NCT06139237

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-protein supplement
Description: High protein supplement 200 mL

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Balanced supplement
Description: Balanced supplement 200 mL
Study: NCT05434481

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mitochondrial dynamic analysis in the aorta samples and metabolomic profiling in the aortic diseases
Description: * For each patient: a segment of aorta will be sampled and cutted into 4 parts~  * 1 fragment placed in a Falcon tube containing DMEM (Dulbecco's Modified Eagle Medium, Thermo Fisher®), temporarily stored at + 4°C, for primary culture of smooth muscle cells will allow analysis of the mitochondrial network.~ * 1 fragment placed in a Falcon tube containing Allprotect Tissue Reagent (QIAGEN®), stored at -80°C for gene (RT-PCR) and protein (Western Blot) analysis.~ * 2 fragments each placed in dry cryotube stored at - 80°C will be used for metabolomic analysis.~* For each patient, 2 arterial blood samples will be collected before general anaesthesia~  * One tube of whole blood stored at -80°C for metabolomic analysis.~ * One tube of blood stored at -80°C for plasma cytokines

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mitochondrial dynamic analysis in the aorta samples and metabolomic profiling in the aortic diseases
Description: * For each patient: a segment of aorta will be sampled and cutted into 4 parts~  * 1 fragment placed in a Falcon tube containing DMEM (Dulbecco's Modified Eagle Medium, Thermo Fisher®), temporarily stored at + 4°C, for primary culture of smooth muscle cells will allow analysis of the mitochondrial network.~ * 1 fragment placed in a Falcon tube containing Allprotect Tissue Reagent (QIAGEN®), stored at -80°C for gene (RT-PCR) and protein (Western Blot) analysis.~ * 2 fragments each placed in dry cryotube stored at - 80°C will be used for metabolomic analysis.~* For each patient, 2 arterial blood samples will be collected before general anaesthesia~  * One tube of whole blood stored at -80°C for metabolomic analysis.~ * One tube of blood stored at -80°C for plasma cytokines

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mitochondrial dynamic analysis in the aorta samples and metabolomic profiling in the aortic diseases
Description: * For each patient: a segment of aorta will be sampled and cutted into 4 parts~  * 1 fragment placed in a Falcon tube containing DMEM (Dulbecco's Modified Eagle Medium, Thermo Fisher®), temporarily stored at + 4°C, for primary culture of smooth muscle cells will allow analysis of the mitochondrial network.~ * 1 fragment placed in a Falcon tube containing Allprotect Tissue Reagent (QIAGEN®), stored at -80°C for gene (RT-PCR) and protein (Western Blot) analysis.~ * 2 fragments each placed in dry cryotube stored at - 80°C will be used for metabolomic analysis.~* For each patient, 2 arterial blood samples will be collected before general anaesthesia~  * One tube of whole blood stored at -80°C for metabolomic analysis.~ * One tube of blood stored at -80°C for plasma cytokines
Study: NCT05875337

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupressure
Description: Before starting the acupressure point application, the area around the area where the pressure will be applied for 20-30 seconds will be gently rubbed with the palm of the hand. By gently rubbing the surrounding tissue, tension and tissue sensitivity will be reduced and the tissue will be relaxed by heating, relaxing and preparing the point area. Pressure will be applied to the determined points (LI4, LI11 and HT7) with the thumb, index or middle finger manually for 5 seconds to create a depth of 1-1.5 cm and rest for 2 seconds. Each point will be applied for 2 minutes and the application will last 12 minutes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo acupressure
Description: Before starting the application to the placebo acupressure point, the area around the area where pressure will be applied for 20-30 seconds will be gently rubbed with the palm of the hand. By gently rubbing the surrounding tissue, tension and tissue sensitivity will be reduced and the tissue will be relaxed by heating, relaxing and preparing the point area. Light pressure will be applied to the determined points (1.5 cm away from LI4, LI11 and HT7 points) with the thumb, index or middle finger. Each point will be applied for 2 minutes and the application will last 12 minutes.
Study: NCT04002388

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: activity monitor group
Description: will receive a FitBit and will be asked to wear this for one year

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: usual care group
Description: will NOT receive a FitBit
Study: NCT06062771

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FIDIAL PLUS
Description: 1.8% solution of sodium hyaluronate that is derived from a bacterial fermentation (not of animal origin).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: IAL®-F
Description: Animal derived 1.8% sodium hyaluronate equivalent to FIDIAL PLUS
Study: NCT04719000

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rhFSH+rhLH
Description: 300 IU of rhFSH and 150 IU of rhLH (Pergoveris®) GnRH antagonist: cetrorelix 0.25 mg (Cetrotide® - Merck) GnRH antagonist: cetrorelix 0.25 mg (Cetrotide® - Merck) Recombinant human chorionic gonadotropin (rhCG) 6500 IU (Ovitrelle® - Merck) micronized progesterone 90 mg (Crinone 8% ® - Merck)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: rhFSH
Description: 300 IU rhFSH (Gonal-F®- Merck) GnRH antagonist: cetrorelix 0.25 mg (Cetrotide® - Merck) GnRH antagonist: cetrorelix 0.25 mg (Cetrotide® - Merck) rhCG 6500 IU (Ovitrelle® - Merck) micronized progesterone 90 mg (Crinone 8% ® - Merck)
Study: NCT05366764

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR443765
Description: solution for injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: solution for injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Salbutamol or levosalbutamol
Description: metered dose inhaler

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol or levosalbutamol
Description: metered dose inhaler
Study: NCT06486246

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adductor canal block
Description: Injection of the local anesthetic prior to the surgery, either in the the adductor canal or in the genicular nerves by the anesthesiologist under ultrasound guidance.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adductor canal block
Description: Injection of the local anesthetic prior to the surgery, either in the the adductor canal or in the genicular nerves by the anesthesiologist under ultrasound guidance.
Study: NCT05087693

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Salbutamol
Description: Inhaling 200ug of salbutamol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhaling 200ug of salbutamol

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo medication
Description: Inhaling placebo medication

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo medication
Description: Inhaling placebo medication

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Ozone
Description: Breathing 170ppb ozone

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ozone
Description: Breathing 170ppb ozone

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Filtered Air
Description: Breathing filtered air

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Filtered Air
Description: Breathing filtered air

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Exercise
Description: Cycling at 60% of VO2max on a cycle ergometer

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Cycling at 60% of VO2max on a cycle ergometer

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Exercise
Description: Cycling at 60% of VO2max on a cycle ergometer

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Cycling at 60% of VO2max on a cycle ergometer
Study: NCT05473052

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Preoperative home-based exercise training
Description: 1) Home-based aerobic and resistance exercise training (preoperative period)~Dose of aerobic exercise:~1. Type: Walking~2. Frequency: 3 sessions per week~3. Duration: 30 minutes~4. Intensity: Rate of perceived exertion on Borg Category Ratio-10 (3-5)~5. Progression: Increase the walking duration in 10 minutes (after week 2)~Dose of resistance exercise:~1. Type: Six exercises for upper and lower limbs using bodyweight and free-wights of 1-2kg~2. Frequency: 2 sessions per week~3. Duration: 2 sets x 15 repetitions~4. Rest in-between sets: 45 seconds~5. Intensity:Rate of perceived exertion on Borg Category Ratio-10 (3-5)~6. Progression: Increase the number of sets (3 sets of 15 repetitions after week~2) Weekly telephone supervision: A physical therapist carried out weekly telephone calls with all participants to monitor adverse events, give positive reinforcement and recommend strategies to overcome barriers that arise during the exercise program.
Study: NCT05817916

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ESP block
Description: ESP block: ultrasound guided erector spina plane block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: LP block
Description: LP block: ultrasound guided lumbar plexus block