TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06432348

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reformer pilates
Description: Before starting the exercises, a 5-minute warm-up session was performed. The reformer Pilates exercise program included movements such as the Footwork Series (Toes, Heels, Tendon Stretch, V Position), Supine Arm Series (Pull, Circle, Pull Head Up, Triceps Press), Short Box Series (Round, Flat Back, Twist), Short Box and Arm Series (Chest Fly, The Gift, Rhomboid, Biceps Curl, Rowing, Triceps), Long Box Series (Swan, Pulling Fly), Stomach Massage (Round, Twist), Knee Stretch (Round, Flat Back), Hip Work Series (Double Leg Press, Hamstring Pulls, Leg Circle, Frog), Elephant, and Side Stretch. Participants had two-minute rest intervals after the Supine Arm Series, Short Box, Arm Series, and Knee Stretch movements. Movements were performed with ten repetitions in the first four weeks and 12 repetitions in the following four weeks. The participants underwent six weekly training sessions over eight weeks, comprising three Reformer Pilates sessions and three team training days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mat Pilates
Description: Before the exercises, a 5-minute warm-up session was performed. The mat Pilates exercise program included movements such as Rol Up, One Leg Circle, Double Leg Straight Lower, One Leg Stretch, Criss Cross, Toe Top, Shoulder Bridge, Seated Tracking, Spine Twist, Up-Down Side Kick, Front-Back Side Kick, Circle Side Kick, Flight, Swan, Rest Position, Swimming, Push Up, Long Stretch, Cat Cow, Mermaid Stretch. The participants had two-minute rest breaks after the toe-top, spine twist, and circle side-kick movements. Movements were performed with ten repetitions in the first four weeks and 12 repetitions in the following four weeks. Movements were performed with ten repetitions in the first four weeks and 12 repetitions in the following four weeks. The participants underwent six weekly training sessions over eight weeks, comprising three Mat Pilates sessions and three team training days.
Study: NCT05094375

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vaginal Misoprostol 600 mcg
Description: All patients will receive three doses of vaginal misoprostol every four hours. The first dose of misoprostol 600 mcg will be administrated at the hospital. Then the patient will be observed for 1 hour for any immediate adverse reaction Clear instructions about the method and timing of the second dose will be given upon sending home.~* Two doses of misoprostol 600 mcg each (3 tablets of 200 mcg per dose).~* Paracetamol, eight hourlies, will be provided as analgesic or antipyretic.~* A specimen bottle to collect the POC if passed out.~* Two pairs of disposable gloves.~* Pre-filled histopathological examination form to be sent to the laboratory together with the products of conception

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal Misoprostol 800 mcg
Description: All patients will receive three doses of vaginal misoprostol every four hours. The first dose of misoprostol 800 mcg will be administrated at the hospital. Then the patient will be observed for 1 hour for any immediate adverse reaction Clear instructions about the method and timing of second dose will be given upon sending home.~* Two doses of misoprostol 800 mcg each (four tablets of 200 mcg per dose).~* Paracetamol, eight hourlies, will be provided as analgesic or antipyretic.~* A specimen bottle to collect the POC if passed out.~* Two pairs of disposable gloves.~* Pre-filled histopathological examination form to be sent to the laboratory together with the products of conception
Study: NCT04678284

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Homeless Medication Support (D-Homes)
Description: There will be 10 sessions offered within 12 weeks to participants. Sessions will last 30-60 minutes. During sessions a diabetes wellness coach will use behavioral activation and motivational interviewing to get to know participants and set goals to improve diabetes care. The coach will encourage a focus on medication adherence behaviors to the extent that participants are willing. The coach will also help with resource and care coordination. The coach will also provide brief diabetes education as needed.
Study: NCT06188429

Intervention type: DIAGNOSTIC_TEST
Intervention: DSM-5
Description: Using DSM-5 for diagnostic testing of the children in the study group.

Intervention type: DIAGNOSTIC_TEST
Intervention: DSM-5
Description: Using DSM-5 for diagnostic testing of the children in the study group.
Study: NCT05958550

Intervention type: BEHAVIORAL
Intervention: The tympanic membrane temperature of patients was measured.
Description: After the patient entered the anesthesia recovery room ( PACU ) at the end of the operation, the ear canal was cleaned with cotton swabs by nurses trained in the use of ear temperature guns to avoid the impact of earwax. The patient was in a supine position, the patient 's head was fixed, the patient 's auricle was gently pulled back and up, the ear canal was straight, the ear temperature gun was put into the ear canal, the temperature of the patient 's left and right ears was measured uniformly, and the average value was taken as the final body temperature value. Thereafter, the same measurement was performed every 20 minutes until the patient left the resuscitation room.

Intervention type: BEHAVIORAL
Intervention: The tympanic membrane temperature of patients was measured.
Description: After the patient entered the anesthesia recovery room ( PACU ) at the end of the operation, the ear canal was cleaned with cotton swabs by nurses trained in the use of ear temperature guns to avoid the impact of earwax. The patient was in a supine position, the patient 's head was fixed, the patient 's auricle was gently pulled back and up, the ear canal was straight, the ear temperature gun was put into the ear canal, the temperature of the patient 's left and right ears was measured uniformly, and the average value was taken as the final body temperature value. Thereafter, the same measurement was performed every 20 minutes until the patient left the resuscitation room.
Study: NCT05812417

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-8010
Description: DA-8010 5mg single dose administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-8010
Description: DA-8010 5mg single dose administration

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DA-8010
Description: DA-8010 5mg single dose administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-8010
Description: DA-8010 5mg single dose administration
Study: NCT03210545

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Betamethasone
Description: A cross-over study where patients with Addison´s disease will undergo two treatment periods where their usual hydrocortisone replacement therapy will be replaced by the glucocorticoid betamethasone in physiological and supra physiological doses. A wash-out period of 2-5 weeks in-between the treatment periods will be carried out where participants intake their usual hydrocortisone replacement therapy.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Betamethasone
Description: A cross-over study where patients with Addison´s disease will undergo two treatment periods where their usual hydrocortisone replacement therapy will be replaced by the glucocorticoid betamethasone in physiological and supra physiological doses. A wash-out period of 2-5 weeks in-between the treatment periods will be carried out where participants intake their usual hydrocortisone replacement therapy.
Study: NCT05766085

Intervention type: DIAGNOSTIC_TEST
Intervention: Dexamethasone suppression test
Description: Determination of cortisol levels at 9.00 am after taking 1 mg of dexamethasone the previous evening at 11.00 pm (1mg DST)

Intervention type: DIAGNOSTIC_TEST
Intervention: Dexamethasone suppression test
Description: Determination of cortisol levels at 9.00 am after taking 1 mg of dexamethasone the previous evening at 11.00 pm (1mg DST)
Study: NCT05873764

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 200 mg RV521/78 µCi [ 14C]-RV521.
Description: 200 mg RV521/78 µCi \[ 14C\]-RV521
Study: NCT05029232

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MLPA for duchenne
Description: MLPA test for genetic testing to detect gene affection in DMD , and other tests for confirmation and follow up

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MLPA for duchenne
Description: MLPA test for genetic testing to detect gene affection in DMD , and other tests for confirmation and follow up
Study: NCT05106413

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BiCROS fitting
Description: Each participant will be fitted with the experimental CROS device on the poorer, unaidable ear and with a compatible hearing device on the other ear.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Monaural fitting
Description: Each participant will be fitted with a hearing aid on the better hearing ear and no device on the poorer, unaidable ear.~Monaural hearing aid fitting acts as control intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unaided condition
Description: No treatment, i.e. the participants are not fitted with a CROS device and/ or hearing aid.~Unaided condition acts as control intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CROS baseline
Description: Each participant will be fitted with the experimental CROS device on the poorer, unaidable ear and with a compatible device on the other ear. The difference to the BiCROS condition is the setup of the microphones in the CROS device and the compatible hearing device.~This test condition is only tested for speech intelligibility in diffuse noise and acts as control intervention.
Study: NCT05027633

Intervention type: DRUG
Group type: OTHER
Intervention: Pembrolizumab
Description: given by IV

Intervention type: DRUG
Group type: OTHER
Intervention: Docetaxel
Description: given by IV

Intervention type: DRUG
Group type: OTHER
Intervention: Cisplatin
Description: given by IV

Intervention type: DRUG
Group type: OTHER
Intervention: Carboplatin
Description: given by IV
Study: NCT04110639

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intracranial pressure (ICP) monitor
Description: The investigators' hypothesis is that by utilizing an intracranial pressure (ICP) monitor to detect the presence or absence of waveforms in the femoral head, investigators could reliably assess the perfusion levels within the femoral head and possibly reduce the incidence of osteonecrosis.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: 10 patients with minimally displaced femoral neck fractures (Garden 1) which will be pinned in situ without manipulation
Study: NCT06375447

Intervention type: OTHER
Intervention: Routine clinical treatment
Description: Routine clinical treatment is based on the latest international guidelines for insomnia.
Study: NCT05260814

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electric toothbrush with smart phone app
Description: Scaling and root planing, oral hygiene instructions with use of Sonicare Diamond Clean Smart®.
Study: NCT06379243

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PVP/PKP
Description: PVP or PKP surgery in patients with osteoporotic vertebral compression fractures
Study: NCT05237401

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-Surgical Periodontal treatment (NSPT)
Description: participants will receive local anaesthesia, then thorough debridement of the root surface will be completed to the depth of the periodontal pocket and of the furcation lesion, by using sonic scaler (KaVo Sonicflex, KaVo, Germany), piezo-electric/ultrasonic devices with specific thin and delicate tips (such as Cavitron, Dentsply Sirona, US) and/or curettes.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Periodontal treatment/ Open Flap Debridement (OFD)
Description: Patients will receive local anaesthesia and intrasulcular incisions will be made on the buccal and lingual/palatal aspects in order to reflect full-thickness flaps. After reflection of the flaps, the granulation tissue around the tooth will be removed with the non-cutting edge of a suitable scaling instrument such as a curette, taking care not to damage the root surfaces. Thorough debridement of the furcation area will be carried out by using diamond coated inserts, sonic scaler (KaVo Sonicflex, KaVo, Germany), piezo-electric/ultrasonic devices with specific thin and delicate tips (such as Cavitron, Dentsply Sirona, US) and/or curettes. Osteoplasty (removal of non-supporting bone) may be carried out, as judged by the operator. The surgical site will be closed with resorbable or non-resorbable sutures.
Study: NCT04847791

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bovine lactoferrin
Description: Oral Administration of Bovine Lactoferrin -fixed dose 800 mg / day for 30 days

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo administration
Description: capsule identical with the same amount as an inert compound, starch of corn powder), according to the same pattern of use.
Study: NCT05972928

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sitagliptin 100mg
Description: Sitagliptin at a dose of 100 mg every 24 hours for 3 months
Study: NCT04664400

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Symbolic conditioning
Description: Participants will learn associations between cues and thermal stimuli with varying temperatures (low vs. high) through symbolic conditioning (no actual heat stimuli, only pictures of thermometers)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conditioning
Description: Participants will learn associations between cues and thermal stimuli with varying temperatures (low vs. high) from experience (with actual heat stimuli).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Instructions
Description: Participants will learn associations between cues and thermal stimuli with varying temperatures (low vs. high) from verbal instructions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counterfactual
Description: Thermal stimuli will be either the better outcome or the worse outcome out of two possible outcomes.
Study: NCT06200012

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-level stigma reduction intervention: educational training plus controlled substance agreement policy change
Description: Pairing a professional training targeting known attitudinal and knowledge drivers of substance use stigma with a policy altering potentially stigmatizing features of controlled substance agreements.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Single-level stigma reduction intervention: educational training
Description: A professional training targeting known attitudinal and knowledge drivers of substance use stigma
Study: NCT06017271

Intervention type: DIAGNOSTIC_TEST
Intervention: CTPA (computed tomography pulmonary angiography)
Description: The CTPA diagnosis suggest or did not suggest pulmonary embolism.

Intervention type: DIAGNOSTIC_TEST
Intervention: CTPA (computed tomography pulmonary angiography)
Description: The CTPA diagnosis suggest or did not suggest pulmonary embolism.
Study: NCT05590169

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Group 1: Group exercises via Zoom application Group 2: Individual exercises via Zoom application Group 3: Routine treatment

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Group 1: Group exercises via Zoom application Group 2: Individual exercises via Zoom application Group 3: Routine treatment
Study: NCT05498389

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EMB-01
Description: EMB-01 is a bispecific antibody against epidermal growth factor receptor (EGFR) and the receptor tyrosine kinase Met (cMET).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib
Description: Osimertinib is an approved, third-generation EGFR tyrosine kinase inhibitor
Study: NCT06474533

Intervention type: DRUG
Intervention: Fluorethyltyrosine (18-F)
Description: Given intravenously (IV)

Intervention type: DRUG
Intervention: Fluorethyltyrosine (18-F)
Description: Given intravenously (IV)

Intervention type: PROCEDURE
Intervention: Positron Emission Tomography (PET)
Description: Undergo Imaging Procedure

Intervention type: PROCEDURE
Intervention: Positron Emission Tomography (PET)
Description: Undergo Imaging Procedure
Study: NCT05319717

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ready-to-use therapeutic food with heat stabilized rice bran
Description: Children assigned to the experimental group will be treated for severe acute malnutrition with a novel ready-to-use therapeutic food that contains 5% heat stabilized rice bran.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ready-to-use therapeutic food (no rice bran)
Description: Children assigned to the active comparator group will be treated for severe acute malnutrition with a novel ready-to-use therapeutic food (no rice bran).
Study: NCT06019871

Intervention type: PROCEDURE
Intervention: Dialysis
Description: Patients who have decided for dialysis either center haemo-dialysis or peritoneal dialysis
Study: NCT06300502

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Kybella
Description: Injection into the cutaneous Neurofibromas lesion.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Asclera
Description: Injection into the cutaneous Neurofibromas lesion.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 755nm Alexandrite Laser
Description: Pulse laser at a wavelength of 755nm to the cutaneous Neurofibromas lesion.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 1064nm Nd:YAG Laser
Description: Pulse laser at a wavelength of 1064nm to the cutaneous Neurofibromas lesion
Study: NCT05189392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PICO
Description: after hip arthroplasty application of visible opsite plaster on the surgical wound
Study: NCT05523843

Intervention type: OTHER
Intervention: Tulsa Life Chart (TLC)
Description: The TLC is a self-administered, interactive assessment of patient history. Participants are asked to provide information from birth to their current age in developmental epochs (i.e., ages 0 to 5; 6 to 10; 11 to 14; 15 to 18; 19 to 25; 26 to 35; and so on in 10-year increments). Participants are first asked to rate their average mood during the epoch. They are then asked about locations lived, schools attended, people they were close to, hobbies, medical conditions, medications, hospitalizations, direct and indirect substance use exposure, mental health symptoms, mental health treatment, and important life events. The information is then displayed in an interactive, graphic of the individual's life that is reviewable by the patient and the healthcare providers enrolled in the study that the patient consents to having access.
Study: NCT05922254

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active cycle of breathing technique
Description: The ACBT technique consists of three different breathing techniques: breathing control, thoracic expansion exercises and forced expiration technique. 1. Breathing Control 2. Thoracic Expansion Exercises: 3. Forced Expiration Technique:

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active cycle of breathing technique
Description: The ACBT technique consists of three different breathing techniques: breathing control, thoracic expansion exercises and forced expiration technique. 1. Breathing Control 2. Thoracic Expansion Exercises: 3. Forced Expiration Technique:

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Autogenic drainage
Description: Huffing or blowing the nose helped to get rid of any secretions in the upper airways. The therapist was placed close enough to hear the subject's breathing while sitting to the side and slightly behind the patient. Both the physiotherapist's hand and the subject's hands were put on the subject's abdomen to feel the activity of the abdominal muscles. The patient inhaled slowly through the nose while using their diaphragm and holding their breath for two to three seconds to allow collateral ventilation to bring air behind their secretions. Exhalation was done through the mouth. The palm of the therapist placed on the upper chest felt the vibration of the mucous. Their positions were disclosed by the vibrations' frequency.
Study: NCT05988359

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Caries treatment with a dental turbine
Description: G1 (n=30) conventional high-volume evacuator (Monoart® Euronda, Vicenza, Italy) was used to remove aerosols during caries treatment.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caries treatment with Er:YAG laser
Description: G2 (test, n=30) group, a conventional high-volume evacuator (Monoart® Euronda, Vicenza, Italy) was used to remove aerosols during caries treatment.
Study: NCT05664516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNX-1900 (Tonix Pharmaceuticals)
Description: oxytocin nasal spray

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Nasal solution without oxytocin
Study: NCT06452342

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid
Description: Tranexamic acid 1.5 grams, orally, three times a day during menstrual cycle for the 3 month study period

Intervention type: OTHER
Group type: OTHER
Intervention: No Tranexamic acid
Description: Routine clinical care without Tranexamic acid
Study: NCT04889040

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RO7496998
Description: 275 mg tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching tablets
Study: NCT06212882

Intervention type: DIAGNOSTIC_TEST
Intervention: Lower concentration and lower volume contrast agent group
Description: CT images using lower concentration and lower volume contrast material

Intervention type: DIAGNOSTIC_TEST
Intervention: Lower concentration and lower volume contrast agent group
Description: CT images using lower concentration and lower volume contrast material
Study: NCT05170633

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ranger blood warmer (3M Healthcare, Oakdale, Minnesota)
Description: 70 random infant will receive the packed red blood cell transfusion with the Ranger blood warmer (3M Healthcare, Oakdale, Minnesota)
Study: NCT06417697

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XEN-101
Description: capsule formulation

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: capsule formulation