TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06765824

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation
Description: The protocol will be applied with the MagVenture R30 stimulation device and the cool-B70 coil for active treatment. The protocol will consist of two sessions per day, with a 50-minute break between sessions, every day of the week (Monday to Friday) for three and a half weeks (a total of 36 sessions). Each session will consist of the application of a 1Hz protocol (2000 pulses at 120% of the motor threshold) in the right dorsolateral prefrontal cortex (F4) followed by an intermittent theta-burst protocol (1800 pulses at 90% of the motor threshold) in the left dorsolateral prefrontal cortex (F3). The cortical target localization will be performed using the beam-F3/F4 technique that combines different electroencephalographic positioning parameters and measurements to accurately locate said cortical targets. The motor threshold of each patient will be calculated at the beginning of each week of treatment using an electromyography system.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Magnetic Stimulation Sham
Description: The same protocol described in the intervention group will be carried out in the control group. The device used is the same, the difference is the coil that maintains the same appearance and generates the same sound as the active treatment coil, but unlike the latter, it does not produce an effective magnetization to depolarize the cerebral cortex on which we act.
Study: NCT06766734

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tendon Dry Needling
Description: Tendon dry needling procedure is that repetitively passing the needle though the area of supraspinatus tendon. Tendon dry needling was performed under sterile conditions with real-time imaging guidance using an ultrasound probe. The supraspinatus tendon was scanned from anterior to posterior, and tendon dry needling was applied to the identified lesion (tendinozis or partial tear) area. This treatment method was applied twice, with a one-month interval between sessions.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham Tendon Dry Needling
Description: In this treatment subcutaneous sham tendon dry needling was performed by randomly holding the ultrasound probe in the area corresponding to the same anatomical localization. Sham tendon dry needling performed to subcutaneus tissue not tendon.
Study: NCT06766214

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation
Description: Simultaneous treatment with tDCS and online-based psychotherapy

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: sham transcranial direct current stimulation
Description: Simultaneous treatment with sham-tDCS and online-based psychotherapy
Study: NCT06765928

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: selinexor in combination with venetoclax
Description: After allo-HSCT, intermediate-high risk MDS/AML patients are maintenanced with selinexor given in combination with venetoclax for 2 years
Study: NCT06766305

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QL1706 combined with SOX
Description: QL1706 + SOX (3 cycles) before surgery → radical surgery (D2) → QL1706 + SOX (5 cycles) after surgery → QL1706 monotherapy maintenance （up to 1 year before and after surgery); Phase 1 (initial dose cohort) ： QL1706 5mg/kg ；Phase 1 (dose escalation cohort)：QL1706 7.5mg/kg ；Phase 2：QL1706 RP2D
Study: NCT06769321

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automatic Thermo-mechanical Massage Bed
Description: The MASTER V6 (Master series, CGM MB-1701, CERAGEM Co. Ltd., Cheonan, Korea) used in this study is a commercially available automated thermo-mechanical therapy device that combines mechanical spinal stimulation with far-infrared (FIR) heat treatment.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Automatic Thermo-mechanical Massage Bed
Description: The MASTER V6 (Master series, CGM MB-1701, CERAGEM Co. Ltd., Cheonan, Korea) used in this study is a commercially available automated thermo-mechanical therapy device that combines mechanical spinal stimulation with far-infrared (FIR) heat treatment.
Study: NCT06766669

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Shaping method activities combined with mirror therapy
Description: This intervention involves the application of exercises consisting of shaping method activities accompanied by a mirror device. It is basically an intervention consisting of exercises that require manual dexterity.
Study: NCT06768463

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cytoreductive Gastrectomy
Description: The patients undergo gastrectomy after 4 cycles of systemic therapy
Study: NCT05303766

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radio-frequency ablation
Description: Radiofrequency thermocoagulation of the genicular nerves
Study: NCT06766279

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Treatment
Description: The OMT intervention in this study will be comprised of an occipitoatlantal (OA) decompression and treatment of the nasal Chapman point. The OA decompression will be applied for 2 minutes with 12N of pressure as this pressure has been determined to produce the greatest effect. Treatment at this level reduces congestion of nasal mucosa. The suboccipital decompression technique is generally considered to bear minimal risks and is perceived by most patients as a pleasant experience. This technique is considered to be a basic skill among osteopathic physicians. It is usually taught within the first semester of the first year at Colleges of Osteopathic Medicine.~The other intervention technique will be addressing the nasal Chapman points that are found at the tip of the transverse process of C1 and the costochondral junction of the first rib on each side. Both techniques are performed while the subject is supine.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham treatment
Description: The sham intervention will consist of the subject lying supine with the investigator's hands resting gently on both sides of subject's neck for 5 minutes.
Study: NCT06766942

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: structured sherborne developmental movement program with sensory integration program
Description: In addition to the sensory integration therapy they receive at the rehabilitation center for 45 minutes, two days a week for 12 weeks, the Structured Sherborne Developmental Movement Program will be applied.
Study: NCT05303766

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intra-articular steroids
Description: Intra-articular steroids for Knee osteoarthritis
Study: NCT06766942

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sensory integration program group
Description: Sensory integration therapy programmed according to the individual's needs and disabilities will be applied to this group by an occupational therapist at the rehabilitation center for 45 minutes, 2 days a week for 12 weeks.

Intervention type: OTHER
Group type: OTHER
Intervention: control group
Description: This group will not participate in any activities outside of the standard special education program.
Study: NCT06767735

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR4
Description: GZR4 s.c., once-weekly，treat-to-target dose

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin Glargine U100
Description: Insulin Glargine U100 s.c.,once-daily，treat-to-target dose
Study: NCT06769178

Intervention type: OTHER
Group type: OTHER
Intervention: Virtual Reality based
Description: Participants will receive treatment by a specialist physiotherapist for a total of 16 sessions, 2 days a week on non-consecutive days for 8 weeks. Both groups will receive neurodevelopmental treatment (NGT) for 16 sessions. While the control group will receive traditional balance training in each session, the VR group will play virtual reality-based games.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality based
Description: Participants will receive treatment by a specialist physiotherapist for a total of 16 sessions, 2 days a week on non-consecutive days for 8 weeks. Both groups will receive neurodevelopmental treatment (NGT) for 16 sessions. While the control group will receive traditional balance training in each session, the VR group will play virtual reality-based games.
Study: NCT06769789

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Drug free invitro activation Ovary
Description: Drug free invitro activation Ovary
Study: NCT06768489

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-79635322
Description: JNJ-79635322 will be administered subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-79635322
Description: JNJ-79635322 will be administered subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab will be administered subcutaneously.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Pomalidomide will be administered orally.
Study: NCT06769750

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: leg-lift maneuver
Description: Patients will be monitored as usual using an SpO2 sensor placed on the index finger of the limb contralateral to the pressure cuff, giving the PI value, a tensiometer taking blood pressure (systolic, diastolic and mean) every 2 minutes, and an ECG.~A transthoracic cardiac echocardiogram will be performed with measurement of the sub-aortic time-velocity integral, and the same measurement will be performed 1 min after a passive leg-lift to see if this maneuver significantly increases systolic ejection volume. The PI value and blood pressure will be measured at each of these maneuvers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: leg-lift maneuver
Description: The perfusion index (PI) value and arterial pressure will be measured at each of manoeuvre
Study: NCT06769919

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Neoadjuvant radiotherapy
Description: The experimental group will receive neoadjuvant systemic therapy combined with neoadjuvant radiotherapy before undergoing surgery
Study: NCT06768359

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual acupuncture and standard therapy
Description: Manual acupuncture is acupuncture needle insertion was done perpendicularly to the acupuncture points GV20, EXHN3, HT7, and PC6 using Huanqiu needle measuring 0.25 x 25mm with mild stimulation rotation technique at a speed of 60x/minute and needle retention for 30 minutes. Therapy was performed every day for 6 days.~Standard therapy is anxiolytic drugs and supportive psychotherapy given to patients according to the decision of the psychiatrist treating the patient.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture and standard therapy
Description: Sham acupuncture is when acupuncture needles are inserted into acupuncture points, but do not actually penetrate the skin, only attached to the plaster. Therapy was performed every day for 6 days.~Standard therapy is anxiolytic drugs and supportive psychotherapy given to patients according to the decision of the psychiatrist treating the patient.
Study: NCT06769685

Intervention type: DRUG
Intervention: Basal therapy
Description: Group A was treated with basal therapy including drugs such as interleukin-11, Ricocin, and Epsilon, and was administered until the PLT was ≥75×109/L.

Intervention type: DRUG
Intervention: rhTPO combined with Heptabopa treatment(group B)
Description: In group B, they were treated with rhTPO and Heptabopa, and were medicated until their PLT was ≥75×109/L.
Study: NCT05303766

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Radio-frequency
Description: Intraarticular Pulsed Radiofrequency of the knee
Study: NCT05999617

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation
Description: Conventional rehabilitation (stretching, strengthening, balance) and dual task exercise training (simple math during active stretching, carrying the ball without dropping child while on the balance pad) will be applied 3 days a week for 12 weeks. Interventions will be implemented individually. Patients will be evaluated before and 12 weeks after the interventions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Conventional rehabilitation (stretching, strengthening, balance) and dual task exercise training (simple math during active stretching, carrying the ball without dropping child while on the balance pad) will be applied 3 days a week for 12 weeks. Interventions will be implemented individually. Patients will be evaluated before and 12 weeks after the interventions.
Study: NCT06769685

Intervention type: DRUG
Intervention: rhTPO combined with Heptabopa treatment(group C)
Description: Ctit patients with platelet counts \<50×109/L were included in group C. All were treated with rhTPO and hypertrombopa and medicated until PLT ≥75×109/L.
Study: NCT05730036

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linvoseltamab
Description: REGN5458 will be administered by intravenous (IV) infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Elotuzumab
Description: Elotuzumab will be administered by IV infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pomalidomide
Description: Pomalidomide capsules will administered by mouth (PO)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Dexamethasone tablets/capsules will be administered PO and/or by IV infusion
Study: NCT05668819

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TH-001
Description: TH001 is a software program intended to treat adults with prediabetes.
Study: NCT05947279

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comparing motor adaptation reaching performance
Description: By comparing motor adaptation reaching performance between these three groups, the investigators can examine how stimulation to each specific area of the brain modulates different aspects of motor adaptation

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comparing motor adaptation reaching performance
Description: By comparing motor adaptation reaching performance between these three groups, the investigators can examine how stimulation to each specific area of the brain modulates different aspects of motor adaptation

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Comparing motor adaptation reaching performance
Description: By comparing motor adaptation reaching performance between these three groups, the investigators can examine how stimulation to each specific area of the brain modulates different aspects of motor adaptation
Study: NCT05160246

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesiology tape
Description: The tape will be fixed without any tension 10 cm below the origin of the rectus femoris muscle. Then 35-50% tension will be applied to the band and descended to the patella. After this point, the Y-shaped band will be terminated to wrap the patella medially and laterally without any tension.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tape
Description: The tape will attach to the rectus femoris without any tension.
Study: NCT06330246

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low oxalate fixed diets pre-colonization
Description: 4 days of fixed eucaloric diet with low oxalate (\< 60 mg/day), normal calcium (600-1000 mg/day)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Moderately high oxalate fixed diets pre-colonization
Description: 4 days of fixed eucaloric diet with moderately high oxalate (250-300 mg/day), normal calcium (600-1000 mg/day)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Colonization with Oxalobacter formigenes
Description: Ingestion of live Oxalobacter formigenes

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low oxalate fixed diets post-colonization
Description: 4 days of fixed eucaloric diet with low oxalate (\< 60 mg/day), normal calcium (600-1000 mg/day)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Moderately high oxalate fixed diets post-colonization
Description: 4 days of fixed eucaloric diet with moderately high oxalate (250-300 mg/day), normal calcium (600-1000 mg/day)
Study: NCT05617300

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Dementia Caregiving
Description: Mindfulness Based Stress Reduction (MBSR) is a standardized program that is both psychoeducation and skills-based, which uses mindfulness meditation practices to help people better cope with their emotions. This study uses a version of MBSR designed specifically for care partners of people living with dementia (PLWD) called Mindfulness Based Dementia Caregiving. Mindfulness Based Dementia Caregiving (MBDC) is a program with 8 weekly 2 hour sessions (plus one extended practice 4 hour retreat) including both formal and informal mindfulness practices, role play, and lectures combined with some dementia-specific education. Participants learn how to incorporate mindfulness practices into day-to-day life to help cope with the challenges and stresses of dementia care.
Study: NCT06542874

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 subcutanous
Description: NNC0487-0111 administered subcutanously (under the skin)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 subcutanous
Description: NNC0487-0111 administered subcutanously (under the skin)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 subcutanous
Description: NNC0487-0111 administered subcutanously (under the skin)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 subcutanous
Description: NNC0487-0111 administered subcutanously (under the skin)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 subcutanous
Description: NNC0487-0111 administered subcutanously (under the skin)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 subcutanous
Description: NNC0487-0111 administered subcutanously (under the skin)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (NNC0487-0111 subcutanous)
Description: NNC0487-0111 placebo administered subcutanously (under the skin)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 oral
Description: NNC0487-0111 administered orally (in the mouth)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 oral
Description: NNC0487-0111 administered orally (in the mouth)
Study: NCT04613141

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WalkingTall-PD
Description: Smart garment (socks, insoles or ankle bands) delivering rhythmic haptic stimuli to the ankle timed with preferred cadence. Smart phone application delivers auditory cues synchronised with haptic stimuli. Smart phone application delivers a neurorehabilitation program.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mobility-plus
Description: Active 'pseudo placebo' comparator using a paper-based body weight exercise program.
Study: NCT06542874

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0487-0111 oral
Description: NNC0487-0111 administered orally (in the mouth)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (NNC0487-0111 oral)
Description: NNC0487-0111 placebo administered orally (in the mouth)
Study: NCT05332093

Intervention type: DIAGNOSTIC_TEST
Intervention: skin biopsy
Description: 4mm skin biopsy

Intervention type: DIAGNOSTIC_TEST
Intervention: skin biopsy
Description: 4mm skin biopsy

Intervention type: DIAGNOSTIC_TEST
Intervention: skin biopsy
Description: 4mm skin biopsy

Intervention type: DIAGNOSTIC_TEST
Intervention: skin biopsy
Description: 4mm skin biopsy

Intervention type: DIAGNOSTIC_TEST
Intervention: skin biopsy
Description: 4mm skin biopsy

Intervention type: DIAGNOSTIC_TEST
Intervention: venous blood sample (plasma, PBMC, WB)
Description: venous blood sample to acquire plasma, PBMCs and whole blood

Intervention type: DIAGNOSTIC_TEST
Intervention: venous blood sample (plasma, PBMC, WB)
Description: venous blood sample to acquire plasma, PBMCs and whole blood
Study: NCT06221800

Intervention type: DIAGNOSTIC_TEST
Intervention: Microbiome
Description: Stool and saliva samples will be collected
Study: NCT05332093

Intervention type: DIAGNOSTIC_TEST
Intervention: venous blood sample (plasma, PBMC, WB)
Description: venous blood sample to acquire plasma, PBMCs and whole blood

Intervention type: GENETIC
Intervention: venous blood sample (HLA)
Description: venous blood sample used for HLA typing

Intervention type: GENETIC
Intervention: venous blood sample (HLA)
Description: venous blood sample used for HLA typing

Intervention type: GENETIC
Intervention: venous blood sample (HLA)
Description: venous blood sample used for HLA typing

Intervention type: GENETIC
Intervention: skin slit
Description: genome sequencing of parasite DNA that is extracted from the skin slit

Intervention type: GENETIC
Intervention: skin slit
Description: genome sequencing of parasite DNA that is extracted from the skin slit

Intervention type: GENETIC
Intervention: skin slit
Description: genome sequencing of parasite DNA that is extracted from the skin slit
Study: NCT05640843

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole Foods Plant-based Diet
Description: The meals will have a low glycemic index and contain vegetables, whole grains, and plant-based fats that have undergone minimal processing. Detailed recommendations for snacks and breakfasts meeting the standard of a WFPBD will also be given to supplement their daily calorie needs with access to education materials. Patients will also receive dietary education and counselling from a research dietitian every 4 weeks for the 12-week intervention period. They will have access to the team for questions and support as needed

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Algae omega 3
Description: Algae omega 3 given twice daily.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo supplements
Description: Placebo supplements given twice daily.
Study: NCT06344572

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SAT-001
Description: Device: SAT-001(a Software as Medical Device) Using SAT-001 application for 48 weeks and wearing single vision spectacles

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Single vision spectacles
Description: Wearing single vision spectacles
Study: NCT06303154

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobiderm Intimate Bra group
Description: At the conclusion of the surgical operation, MOBIDERM Intimate bra will be placed on the patient by the medical team. It will be recommended for the patients to wear MOBIDERM Intimate Bra during day and night for 3 weeks after the surgery, and as much time as the patients tolerate the device during the rest of the study, until 6 months after radiotherapy