TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05943054

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temporal perception tasks
Description: A long temporal perception task in which the duration of the stimulus, around 2 min, is materialized by a video. For each trial, two videos are displayed to the participants, and then the task of the participant is to indicate the longest video and to give his level of confidence in his answer. A short temporal perception task which will take place in the same way as the long task except that the duration of the stimulus, around 2 seconds, is materialized by still frames from the videos used in the previous task.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Temporal perception tasks
Description: A long temporal perception task in which the duration of the stimulus, around 2 min, is materialized by a video. For each trial, two videos are displayed to the participants, and then the task of the participant is to indicate the longest video and to give his level of confidence in his answer. A short temporal perception task which will take place in the same way as the long task except that the duration of the stimulus, around 2 seconds, is materialized by still frames from the videos used in the previous task.
Study: NCT05379439

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structured Family Deliberation
Description: Intervention families will be guided through the six modules included in the web-based decisional aid using a Structured Family Deliberation Tool. Parents will view narrated videos corresponding to each module and will be asked a series of questions related to their own lives and values. The process will continue until all modules are reviewed and all questions are completed.
Study: NCT06444802

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linezolid
Description: Linezolid dosing will be adapted according to a model informed precision dosing (TDMx)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Linezolid
Description: Linezolid dosing will be adapted according to a model informed precision dosing (TDMx)
Study: NCT05943054

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temporal perception tasks
Description: A long temporal perception task in which the duration of the stimulus, around 2 min, is materialized by a video. For each trial, two videos are displayed to the participants, and then the task of the participant is to indicate the longest video and to give his level of confidence in his answer. A short temporal perception task which will take place in the same way as the long task except that the duration of the stimulus, around 2 seconds, is materialized by still frames from the videos used in the previous task.
Study: NCT05668845

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PG-ANB performed at the outset of LSG
Description: The paragastric lesser omentum neural block is performed with a 25-gauge needle attached to a venous catheter extension introduced through the left 12-mm port. The needle is capped during its introduction, and the cap is removed inside the abdomen using a grasper and kept under direct vision. Infiltration of 20 mL of non-diluted 0.5% bupivacaine is performed at six levels with careful aspiration preceding fluid infiltration. Four areas are adjacent to the vagus nerves and branches, and two are in the vicinity of the common hepatic and left gastric arteries. This is performed at the outset of the LSG.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PG-ANB performed at the end of the LSG
Description: The paragastric lesser omentum neural block is performed with a 25-gauge needle attached to a venous catheter extension introduced through the left 12-mm port. The needle is capped during its introduction, and the cap is removed inside the abdomen using a grasper and kept under direct vision. Infiltration of 20 mL of non-diluted 0.5% bupivacaine is performed at six levels with careful aspiration preceding fluid infiltration. Four areas are adjacent to the vagus nerves and branches, and two are in the vicinity of the common hepatic and left gastric arteries. This is performed at the end of the LSG\>
Study: NCT05726786

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunonutrition
Description: Immunonutrition: Oral Impact®, Nestlé Health Science, Switzerland.~IN will be administered as per manufacturer suggestion, i.e. three times a day during 7 days preoperatively. Oral Impact® is a powdered oral feed that provides 309 kcal/bag
Study: NCT05985629

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IPACK
Description: Infiltration between the popliteal artery and capsules of the knee (IPACK) is a novel ultrasound-guided technique that provides additional regional analgesic relief to the posterior aspect of the knee without complications seen in a sciatic nerve block. The intention of the IPACK block is to anesthetize the terminal sensory nerves while sparing the main trucks of the common peroneal and tibial nerves.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PLACEBO
Description: The control group will receive the normal pre-procedure care including a pre-operative visit, surgery, and post-operative care. The control group will receive a sham block consisting of saline in the same anatomical location and manner that the intervention IPACK block is administered.
Study: NCT05084482

Intervention type: OTHER
Intervention: Prediction models
Description: The prediction scores are validated by the CAM-ICU scores up to 14 days after ICU admission.
Study: NCT05584189

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rapid SARS-CoV-2 Antigen Test
Description: Candidate Ag self-test kit anterior nasal specimen collection and testing will be done under the supervision of qualified site personnel in person.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rapid SARS-CoV-2 Antigen Test
Description: Candidate Ag self-test kit anterior nasal specimen collection and testing will be done under the supervision of qualified site personnel in person.
Study: NCT06456281

Intervention type: DIAGNOSTIC_TEST
Intervention: A noninvasive cfDNA multi-omics assay
Description: Peripheral venous blood samples will be collected from pancreatic cancer patients, individuals with precancerous lesions, and healthy controls. Subsequently, cfDNA will be extracted and subjected to low-pass whole genome sequencing (LP-WGS) and hybrid capture-based targeted methylation sequencing (TMS).

Intervention type: DIAGNOSTIC_TEST
Intervention: A noninvasive cfDNA multi-omics assay
Description: Peripheral venous blood samples will be collected from pancreatic cancer patients, individuals with precancerous lesions, and healthy controls. Subsequently, cfDNA will be extracted and subjected to low-pass whole genome sequencing (LP-WGS) and hybrid capture-based targeted methylation sequencing (TMS).

Intervention type: DIAGNOSTIC_TEST
Intervention: A noninvasive cfDNA multi-omics assay
Description: Peripheral venous blood samples will be collected from pancreatic cancer patients, individuals with precancerous lesions, and healthy controls. Subsequently, cfDNA will be extracted and subjected to low-pass whole genome sequencing (LP-WGS) and hybrid capture-based targeted methylation sequencing (TMS).
Study: NCT04379401

Intervention type: DEVICE
Group type: OTHER
Intervention: Cardiac Resynchronization Therapy (ON vs. OFF)
Description: This study involves study participants, who already received cardiac resynchronisation therapy implantation for clinical reasons. CRT is authorized for medical use by Swissmedic in Switzerland and all implanted devices are CE-approved.

Intervention type: DEVICE
Group type: OTHER
Intervention: Cardiac Resynchronization Therapy (ON vs. OFF)
Description: This study involves study participants, who already received cardiac resynchronisation therapy implantation for clinical reasons. CRT is authorized for medical use by Swissmedic in Switzerland and all implanted devices are CE-approved.
Study: NCT05352425

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MobiusHD
Description: The MobiusHD® device is a nickel-titanium device that is implanted in the internal carotid sinus using a minimally invasive approach.
Study: NCT06099392

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: digital stimulators (SNM-FDC01, Ningbo MaidaMedical Device, Inc, Ningbo, China)
Description: TEA at Zusanli(ST 36) 45 min when drinking Polyethylene Glycol Electrolytes Powder
Study: NCT05993676

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: MeT4VeT mobile phone app: control
Description: The control/ sham comparator arm of the Mental Health Toolkit for Veterans (MeT4VeT) smart phone app contains only signposting information around support services available to military veterans

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MeT4VeT mobile phone app: intervention
Description: The Mental Health Toolkit for Veterans (MeT4VeT) smart phone app has been developed through careful and close collaboration with military veterans and key providers of veterans' mental healthcare services. The aim of this app is to provide both a degree of education to support military veterans' understanding of mental health and foster self-recognition and management of mental health symptoms whilst also encouraging those who need it to seek more formal support.~The elements of the app have been chosen for inclusion as they represent the intersection between:~1. Core components of cognitive behavioural therapy, the theoretical framework underwriting the app~2. Behaviour change constructs
Study: NCT06065826

Intervention type: OTHER
Intervention: Assessment
Description: All subjects will be assessed for FHP by taking a lateral view picture to calculate the CVA using the Kinovea software. Each subject with FHP will be examined for myofascial trigger points done by the therapist finger to palpate bilaterally on tender nodules in masticatory and neck muscles. Then using a pressure algometer, the PPT value will be scored for each trigger in each muscle bilaterally. Masticatory muscle endurance will be measured by asking the subject to bite on load sensor for as long as the subject can until exhaustion. Using a stopwatch, the time will be recorded in seconds. Using the craniocervical extension endurance test, the subject will lie prone with their head unsupported and with a bubble inclinometer attached to their head. Using a stopwatch, time in seconds will be recorded to test how long the subject can sustain the neck in neutral position. Finally, a smartphone addiction scale will be answered by the subject to identify how much they are addicted to its use.

Intervention type: OTHER
Intervention: Assessment
Description: All subjects will be assessed for FHP by taking a lateral view picture to calculate the CVA using the Kinovea software. Each subject with FHP will be examined for myofascial trigger points done by the therapist finger to palpate bilaterally on tender nodules in masticatory and neck muscles. Then using a pressure algometer, the PPT value will be scored for each trigger in each muscle bilaterally. Masticatory muscle endurance will be measured by asking the subject to bite on load sensor for as long as the subject can until exhaustion. Using a stopwatch, the time will be recorded in seconds. Using the craniocervical extension endurance test, the subject will lie prone with their head unsupported and with a bubble inclinometer attached to their head. Using a stopwatch, time in seconds will be recorded to test how long the subject can sustain the neck in neutral position. Finally, a smartphone addiction scale will be answered by the subject to identify how much they are addicted to its use.
Study: NCT04848935

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CURATE.AI
Description: CURATE.AI will be utilised to provide personalised training intensity recommendations (low, medium or high) to the patients during the digital cognitive test battery DI session. The difficulty of each task will be modulated by CURATE.AI by adjusting the frequency of critical events that demand evaluation and/or response.
Study: NCT04068493

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced Project Health
Description: A dissonance-based obesity intervention consisting of eight weekly groups sessions (1.5 hours).
Study: NCT04964882

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ultrasound examination of air insufflation in the upper esophageal region and stomach
Description: Presence of air insufflation is assessed using ultrasound in the upper esophageal region and stomach during face mask ventilation
Study: NCT06199791

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lamotrigine 100 MG
Description: tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lamotrigine 100 MG
Description: tablets
Study: NCT05175040

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Prophylactic manual rotation
Description: Prophylactic manual rotation, performed in the experimental arm, involves a vaginal examination performed with an obstetric provider's hands to turn the baby from a position in which the baby's face is looking up in the direction of the ceiling (occiput posterior) or to the side (occiput transverse) to a position in which the baby's face is looking down in the direction of the mother's spine (occiput anterior). Prophylactic manual rotation will occur at the initiation of pushing once the individual achieves complete cervical dilation, performed by a trained study investigator (M.D. or midwife) to maintain blinding of the patient's primary obstetrician.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham rotation
Description: Sham rotation, performed in the comparator arm, involves a vaginal exam that obstetric providers commonly do with their hands to assess cervical dilation and fetal position during routine labor, and will occur at the initiation of pushing once the individual achieves complete cervical dilation. Duration of the vaginal exam for sham rotation will be consistent with that used for prophylactic manual rotation and will be performed by a trained study investigator (M.D. or midwife) to maintain blinding of the patient's primary obstetrician.
Study: NCT05119751

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: tree 12 SQ-Bet
Description: DAILY DOSE OF AIT TABLET
Study: NCT05091268

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: All participants will attend a four-hour pain education session including gynecologist, psychologist, sexologist, and physiotherapist at Akershus University Hospital.~The education will be held twice, with half of the participants at the time. The training group will then attend a 60 minutes weekly group training session led by a physiotherapist with specialist training in women's health over a period of four months. In addition, participants will perform a progressive home exercise program performed daily over the same period. The focus will be general strength training using own body weight and cardiovascular fitness (walking, low-impact aerobic exercise), stretching, and relaxation
Study: NCT05814952

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: LX103 Injection
Description: Qualified subjects will receive a single unilateral intravitreal injection of LX103 at Day 0 in the trial.
Study: NCT06262841

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Piezosurgery
Description: Piezosurgery used as an osteotomy device
Study: NCT05119751

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: GRASS 2800 BAU
Description: DAILY DOSE OF AIT TABLET

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RAGWEED 12 AMB A 1-U
Description: DAILY DOSE OF AIT TABLET

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: HDM 12 SQ-HDM
Description: DAILY DOSE OF AIT TABLET
Study: NCT05615948

Intervention type: DRUG
Group type: OTHER
Intervention: VTS-K
Description: Proprietary oral formulation of 486mg aspirin and 80mg ketamine
Study: NCT05386368

Intervention type: DRUG
Group type: OTHER
Intervention: ReCell
Description: The perioral area of the face will be treated with CO2 laser. Randomization would occur before study initiation with subjects assigned either left perioral or right perioral RECELL treatment based on their subject enrollment number. The study team member who prepares and blinds the RECELL will create the list of subject ID numbers with subject ID number randomly assigned to either left perioral or right perioral treatment group. This will be completed prior to any patient enrollment in the study. Intraoperatively, RECELL and Placebo will be provided to surgeons and assistants in opaque application devices prepared by a trained, designated study team member.~Both the treatment and placebo sides, will be dressed with a standard autologous cell suspension post treatment dressing (Telfa Clear and Xeroform).

Intervention type: DRUG
Group type: OTHER
Intervention: ReCell
Description: The perioral area of the face will be treated with CO2 laser. Randomization would occur before study initiation with subjects assigned either left perioral or right perioral RECELL treatment based on their subject enrollment number. The study team member who prepares and blinds the RECELL will create the list of subject ID numbers with subject ID number randomly assigned to either left perioral or right perioral treatment group. This will be completed prior to any patient enrollment in the study. Intraoperatively, RECELL and Placebo will be provided to surgeons and assistants in opaque application devices prepared by a trained, designated study team member.~Both the treatment and placebo sides, will be dressed with a standard autologous cell suspension post treatment dressing (Telfa Clear and Xeroform).
Study: NCT05642598

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pivot for Vape
Description: Pivot for Vape vaping cessation smartphone app and program
Study: NCT06469437

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Providing the physicians with a proposed glycated hemoglobin target
Description: Through the geriatric assessment, the investigators will categorize the groups proposed by the Diabetes Canada Clinical Practice Guidelines Expert Committee guideline recommendations into functionally independent, functionally dependent and frail. The investigators will provide the physician with the glycated hemoglobin target proposed by the guideline.
Study: NCT05907031

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active continuous Theta Burst Stimulation
Description: Each patient will receive two 600-pulse cTBS stimulations per day, parted by a 15-minute rest period (a total of 1200 pulses daily), for 3-week treatment, with 5 consecutive days each week.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham continuous Theta Burst Stimulation
Description: Each patient will receive two sham 600-pulse cTBS stimulations per day, parted by a 15-minute rest period (a total of 1200 pulses daily), for 3-week treatment, with 5 consecutive days each week.
Study: NCT05780957

Intervention type: OTHER
Intervention: MCED
Description: multi-cancer early detection (MCED) test
Study: NCT05404321

Intervention type: OTHER
Intervention: Establishment of ex vivo breast cancer organoid models
Description: This study includes 2 steps: The constitution of a collection of tumor and blood samples and the analysis of the ex vivo response of the tumor samples to the treatments for the development of functional tests and the research of predictive biomarkers of this response
Study: NCT05048329

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-invasive continuous remote monitoring with structured escalation pathway
Description: Continuous patient monitoring through non-invasive biosensors coupled with machine learning algorithms, with a structured escalation and communication pathway for home health providers and colorectal clinical team

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Affective Analysis of Participant Response to Continuous Remote Patient Monitoring
Description: Surveys and interviews with enrolled participants
Study: NCT05343936

Intervention type: OTHER
Intervention: Active surveillance
Description: The active surveillance protocol involves a TRUS prostate biopsy at eligibility, at 12 months and then every two years. MRI with or without biopsy at eligibility and then every two years. Clinical evaluation with digital rectal examination and PSA every 6 months. Every year a quality of life and anxiety evaluation are planned.~A new prostate biopsy is indicated if biochemical progression by PSA or changes in multiparametric MRI. Triggers for definitive intervention are biopsy pathological reclassification with Gleason score greater than 6, clinical progression or patient's request.
Study: NCT05723939

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carnosine supplementation
Description: Intake of carnosine supplement in form of capsules or functionally enriched chicken meet for three weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Controls
Description: Intake of placebo capsules or regular chicken meet for three weeks
Study: NCT06191588

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: INFANT CIMT/BIT
Description: Constraint induced movement therapy (CIMT) and Bimanual Intensive therapy (BIT)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: INFANT CIMT/BIT
Description: Constraint induced movement therapy (CIMT) and Bimanual Intensive therapy (BIT)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: INFANT CIMT/BIT
Description: Constraint induced movement therapy (CIMT) and Bimanual Intensive therapy (BIT)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: INFANT CIMT/BIT
Description: Constraint induced movement therapy (CIMT) and Bimanual Intensive therapy (BIT)
Study: NCT06550557

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: counselling sessions
Description: the counselling sessions were adopted from the health belief model with the cues of action depending on mobile phones as muting notifications, removing social media and using computers instead if possible.
Study: NCT05271448

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Continue ACEI or ARBs ( Enalapril , Ramipril , Valsartan , Candesartan, Losartan )
Description: Randomized to continue on prescribed ACE1 or ARBs ( Enalapril 5, 10, 20 mg // Ramipril 2.5 , 5 mg // Valsartan 80 , 160 mg // Candesartan 8, 16 mg // Losartan 50 mg )

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hold ACEI or ARBs
Description: Angiotensin converting enzyme inhibitor or angiotensin receptor blocker held at least 24 hours pre-cardiac catheterization and restarted 48-72 hours post-catheterization (after creatinine measurement)~Other Name: Includes all ACEI inhibitors or ARBs
Study: NCT04999657

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Non-invasive low-frequency tibial nerve stimulator (TNS-01)
Description: The investigational device is a transcutaneous electrical nerve stimulation (TENS) device that is designed to provide stimulation to the nerves at the site of application via surface electrodes temporarily adhered to the skin.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Non-invasive low-frequency tibial nerve stimulator (TNS-01)
Description: The investigational device is a transcutaneous electrical nerve stimulation (TENS) device that is designed to provide stimulation to the nerves at the site of application via surface electrodes temporarily adhered to the skin.