TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05782114

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Extracorporeal Shockwave therapy
Description: The shockwave will be applied for the experimental group (Group A). The patients will be positioned on a chair, and the hand with the disorder will be placed on a surface with the radio ulnar joint will be in mid position and the thumb will be directed up. will be 1000 impulses with 2 bar pressure at a frequency of 15 Hz on the radial head and focused on the tissue surrounding the maximal pain point.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physical therapy program
Description: 1. Instruction to wear Thumb Spica splint:~   The Thumb Spica splint will be used for 4 weeks for both groups of patients.~2. Ultrasound Therapy:~   Therapeutic Ultrasound parameters will be mode: continuous, duration: 5 minutes, intensity: 1.2watt/cm2 and frequency: 1MHZ.~3. Stretching exercise:~1. Self-stretch of the thenar eminence: 2. Opposition stretches: 3. Wrist stretch:~4) Strengthening exercise:~1. Resisted exercise for thumb extension:~2. Resisted exercise for thumb abduction:~3. Resisted exercise for thumb opposition:~4. Wrist radial deviation strengthening:~5. Grip strengthening:~6. Finger spring:

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physical therapy program
Description: 1. Instruction to wear Thumb Spica splint:~   The Thumb Spica splint will be used for 4 weeks for both groups of patients.~2. Ultrasound Therapy:~   Therapeutic Ultrasound parameters will be mode: continuous, duration: 5 minutes, intensity: 1.2watt/cm2 and frequency: 1MHZ.~3. Stretching exercise:~1. Self-stretch of the thenar eminence: 2. Opposition stretches: 3. Wrist stretch:~4) Strengthening exercise:~1. Resisted exercise for thumb extension:~2. Resisted exercise for thumb abduction:~3. Resisted exercise for thumb opposition:~4. Wrist radial deviation strengthening:~5. Grip strengthening:~6. Finger spring:
Study: NCT06327893

Intervention type: OTHER
Intervention: Submersion or immersion in liquid
Description: The patient must have been submersed or immersed in liquid.
Study: NCT05859776

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AXT107 Low Dose
Description: Single suprachoroidal injection of AXT107 (0.125 mg/eye)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AXT107 Mid Dose
Description: Single suprachoroidal injection of AXT107 (0.250 mg/eye)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AXT107 High Dose
Description: Single suprachoroidal injection of AXT107 (0.500 mg/eye)
Study: NCT06010186

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound measurement of the diaphragm and intercostals
Description: The specific research procedures correspond to the addition of :~* Two additional ultrasound examinations, i.e. at discharge from intensive care and 3 months after hospital discharge: non-invasive examination (duration 20 minutes). Ultrasound is a risk-free, painless procedure involving the placement of an ultrasound probe on the body part under investigation, without the need for a radius or puncture.~* Questionnaires to assess quality of life (SF-36) and functional impact (LCADL) of dyspnea, carried out at discharge from hospital and at 3 months (duration 15 minutes).
Study: NCT05007301

Intervention type: DEVICE
Intervention: geko device
Description: Neuromuscular electrostimulation of the peroneal nerve, 12h per day, for up to 12 weeks.
Study: NCT05980390

Intervention type: DIAGNOSTIC_TEST
Intervention: IL 35 in tissue biopsy
Description: Elisa testing

Intervention type: DIAGNOSTIC_TEST
Intervention: IL 35 in tissue biopsy
Description: Elisa testing

Intervention type: DIAGNOSTIC_TEST
Intervention: IL 35 in tissue biopsy
Description: Elisa testing
Study: NCT05143853

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: non-absorbable tape fixation around AC joint
Description: fixation around AC joint with tape in different configurations

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: no fixation around AC joint
Description: there will be no additional fixation around AC joint in this group
Study: NCT05534750

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard quadruple therapy arm
Description: Patients will be taken :~ISONIAZIDE :~o A dosage of 5mg / kg / day for 7 days (to be taken in the morning on an empty stomach) of Isoniazid (RIMIFON®)~RIFAMPICINE :~o A dosage of 10mg / kg / day for 7 days (to be taken in the morning on an empty stomach)~ETHAMBUTOL :~o A dosage of 15-20mg / kg / day for 7 days (to be taken in the morning on an empty stomach) of Ethambutol~PYRAZAMIDE :~o A dosage of 20-25mg / kg / day for 7 days (to be taken in the morning on an empty stomach) of Pyrazinamide~Then, the early bactericidal activity will be measured and compared to the other arms.
Study: NCT05143853

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: coracoclavicular (CC) fixation
Description: mandatory coracoclavicular fixation with to suspensory systems, comprised of non-absorbable tapes and metal buttons

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: coracoclavicular (CC) fixation
Description: mandatory coracoclavicular fixation with to suspensory systems, comprised of non-absorbable tapes and metal buttons
Study: NCT04287803

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methoxyflurane
Description: Methoxyflurane 3mls will be self administered by patients meeting the inclusion criteria with acute traumatic pain scores \>=4
Study: NCT06046469

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: CT with contrast
Description: CT abdomen and pelvis with IV contrast

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MRI pelvis
Description: MRI pelvis with contrast

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TURBT
Description: transurethral resection of bladder tumor

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TURBT
Description: transurethral resection of bladder tumor
Study: NCT05497258

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Artificial intelligence assistant system
Description: The AI-assisted diagnosis system can provide the direction of disease diagnosis in real time and assist the doctor to give the final diagnosis
Study: NCT05754515

Intervention type: PROCEDURE
Intervention: target controlled infusion (TCI) group
Description: Patients in the TCI group will be anesthetized with propofol and remifentanil throughout the operation.~Patients included in the inhalation anesthesia group will be anesthetized with desflurane and remifentanil with a bispectral index of 40-60 throughout the operation.

Intervention type: PROCEDURE
Intervention: target controlled infusion (TCI) group
Description: Patients in the TCI group will be anesthetized with propofol and remifentanil throughout the operation.~Patients included in the inhalation anesthesia group will be anesthetized with desflurane and remifentanil with a bispectral index of 40-60 throughout the operation.
Study: NCT06520631

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ice packs (cryotherapy)
Description: One group of patients receives ice pack applied on the site of the cannulation, for 20 sessions (3 sessions per week) it introduced for 5-10 minutes before the beginning of the dialysis.~The second group of patients receives ice pack applied on contralateral to the site of the cannulation, for 20 sessions (3 sessions per week) it introduced for 5-10 minutes before the beginning of the dialysis.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ice packs (cryotherapy)
Description: One group of patients receives ice pack applied on the site of the cannulation, for 20 sessions (3 sessions per week) it introduced for 5-10 minutes before the beginning of the dialysis.~The second group of patients receives ice pack applied on contralateral to the site of the cannulation, for 20 sessions (3 sessions per week) it introduced for 5-10 minutes before the beginning of the dialysis.
Study: NCT06378645

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: General Anesthesia: Propofol
Description: Transurethral surgery at the Department of Urology (University Hospital Zurich) performed under study arm-specific anesthesia.~Propofol will be administered intravenously using the target-controlled infusion algorithm with effect site concentrations between 1.5-4.0 µg/ml necessary.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: General Anesthesia: Sevoflurane
Description: Transurethral surgery at the Department of Urology (University Hospital Zurich) performed under study arm-specific anesthesia.~Sevoflurane will be given in gaseous form via the endotracheal tube in concentrations between 1.5-2.5% Vol.
Study: NCT06287619

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monoferric Injectable Product
Description: Ferric derisomaltose will be prepared by an unblinded research pharmacist as per standard of care procedures. Specifically, 10 mL (containing 1000 mg ferric derisomaltose) will be diluted in 100 mL of sterile 0.9% sodium chloride solution and drawn up into blinded syringes and tubing. The 1000 mg doses of ferric derisomaltose will be administered by a bedside nurse over 60 minutes via an infusion pump through a dedicated IV.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% sodium chloride solution
Description: Patients in the control group will receive placebo, which will be 100 mL of sterile 0.9% sodium chloride solution and drawn up into blinded syringes and tubing according to good manufacturing practice (GMP).
Study: NCT05471102

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Study group: lower segment resection with ligation of the anterior division of the internal iliac artery
Description: Cases managed by uterine lower segment resection with ligation ((suturing)) of the anterior division of the internal iliac artery (4 cm distal to the bifurcation of the common iliac artery); in addition to the bilateral uterine artery ligation at 2 levels; bilateral ligation at a level below the lower most placental part followed by bilateral uterine artery ligation at the level of the hysterotomy incision.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Control group: lower segment resection without ligation of the anterior division of the internal iliac artery
Description: Cases managed by uterine lower segment resection without ligation of the anterior division of the internal iliac artery. (i.e., only bilateral ligation at a level below the lower most placental part followed by bilateral uterine artery ligation at the level of the hysterotomy incision).
Study: NCT04890639

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acute Intermittent Hypoxia
Description: Four hypoxia sessions, consisting of 15 cycles of hypoxia (21%, 17%, 13% or 9% O2), each of which lasts up to 60 seconds, interspersed with up to 90-second normoxic episodes.
Study: NCT05210010

Intervention type: DEVICE
Group type: OTHER
Intervention: CA-4F
Description: The study intervention is the CA-4F algorithm developed by Ensho Health.~The algorithm is a process for converting input parameters to a CA-4F Risk Score intended to facilitate clinical prioritization of patients suitable for follow-up investigation for ATTR-CM.~The algorithm is applied using the CA-4F Likelihood Estimator which encodes it in software and records its outputs. The CA-4F Likelihood Estimator is controlled through a graphical user interface called the CA-4F Controller.~The CA-4F Likelihood Estimator and its Controller are Class I medical devices in Canada registered under the Medical Device Establishment License of Ensho Health (license 16208).
Study: NCT05998200

Intervention type: OTHER
Group type: OTHER
Intervention: Serum with low concentration AHA (1% Glycolic acid and Lactic acid) and PGA
Description: Participants will used the serum twice daily for 8 weeks
Study: NCT05725954

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GUT LINK SmartPath
Description: A virtual care delivery and referral support tool for primary healthcare providers.
Study: NCT06482476

Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of Lp(a) levels
Description: Collection of a venous blood sample for the measurement of Lp(a) levels using standardized laboratory methods
Study: NCT04734249

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib(HMPL-012)
Description: 1. Cohort 1:Surufatinib(250mg ,qd,po)+mFOLFOX6/FOLFIRI,14 days for a cycle.The curative effect was evaluated every 4 cycles.~   Cohort 2:Surufatinib(250mg ,qd,po)+FOLFOXIRI,14 days for a cycle.The curative effect was evaluated every 4 cycles.~2. if the first-line chemotherapy was used FoLFOX ,the second-line is FOLFIRI,or the first-line chemotherapy was used FOLFIRI ,the second-line is FoLFOX.~3. Second-line Surufatinib Combined With Chemotherapy in Advanced CRC.
Study: NCT05924997

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: adebrelimab, camrelizumab plus apatinib
Description: adebrelimab (RP2D, Q3W)+ camrelizumab 200mg Q3W+ apatinib 250mg qd, with 3 weeks (21 days) as a treatment cycle
Study: NCT05028179

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: EchoGo
Description: EchoGo Pro is an software Medical Device which is able to assess Stress Echocardiograms and provide a binary classification of risk of CAD
Study: NCT05837949

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MS FIT: Falls Insight Track
Description: Participants will respond to a set of surveys every two weeks to increase communication on falls with their clinician.
Study: NCT06048068

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational Informational Platform
Description: This intervention contains many informational articles for surrogates about cardiac arrest, the subsequent hospitalization, and the emotional journey following cardiac arrest. All articles are available in both English and Spanish.
Study: NCT04883528

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacubitril / Valsartan Oral Tablet [Entresto]
Description: sacubitril/valsartan (LCZ696) tablet with minimum dose 24/26 mg, maximum dose 97/103 mg twice daily administered orally.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: sacubitril/valsartan matching placebo tablet with minimum dose 24/26 mg, maximum dose 97/103 mg twice daily administered orally.
Study: NCT05536622

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: High resolution infrared imaging
Description: High resolution infrared imaging of limb of concern and unaffected limb (control).
Study: NCT06279689

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound scans
Description: Ultrasound scans connected with an application enabling the measurement of the force applied.
Study: NCT04748965

Intervention type: DIAGNOSTIC_TEST
Intervention: Digital Subtraction Angiography
Description: Compare optical coherence tomography lesion sizing and characteristics compared to traditional digital subtraction angiography
Study: NCT06176651

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Miebo
Description: Subjects will be instructed to use the Miebo eye drop four times per day in both eyes during their participation in clinical trial. The subjects will be required to remove their contact lenses prior to instillation of the Miebo eye drop and must wait 30 minutes before reinserting their contact lenses.
Study: NCT04731792

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: a bronchial fibroscopy with a virtual reality helmet
Study: NCT04810065

Intervention type: OTHER
Group type: OTHER
Intervention: SingStrong: Strong lungs through Song
Description: Participants who have been clinically diagnosed with Covid-19 and who continue to suffer residual adverse effects on the lung health will be invited to participate in the study.~The intervention will involve biweekly hour-long breathing and singing classes that are designed to correct dis-ordered breathing, and retrain the principal muscles of respiration.~Pre and post evaluation of participant bio-psychosocial health and wellness will be conducted. Triangulation of data using focus groups and individual interviews will be conducted after conclusion of the intervention,
Study: NCT04874805

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Measurement of oxygen saturation
Description: Measurement of oxygen saturation by pulse oximetry once a day, at 6 a.m., for a minimum of 3 days, thanks to three pulse oximeters (1 measurement point per device/day), in parallel with a synchronous sampling, programmed as part of the usual care, of arterial gasometry.
Study: NCT04001946

Intervention type: DEVICE
Group type: OTHER
Intervention: Button Huggie
Description: low profile, external securement device for G-buttons
Study: NCT05651607

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol
Description: Oral solution, taken 3 times a day (morning, noon and evening), 5 mg/kg/day from day D0 to day D4. If not effective and well tolerated, dose increase : 10 mg/kg/day from day D5 to day D9, then 20 mg/kg/day from day D10 to day D29, maximum 800 mg/day
Study: NCT04624334

Intervention type: OTHER
Intervention: Elektro-Entero-Graphy procedure
Description: Fasting, after which pre- and postprandial EEnG measurements are performed.

Intervention type: OTHER
Intervention: Elektro-Entero-Graphy procedure
Description: Fasting, after which pre- and postprandial EEnG measurements are performed.

Intervention type: OTHER
Intervention: Elektro-Entero-Graphy procedure
Description: Fasting, after which pre- and postprandial EEnG measurements are performed.

Intervention type: OTHER
Intervention: Elektro-Entero-Graphy procedure
Description: Fasting, after which pre- and postprandial EEnG measurements are performed.
Study: NCT06482528

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imagery
Description: After the measurement devices are connected to the individuals, they will be seated in a comfortable chair.~After the calibration of the devices, individuals will undergo a 2-minute relaxation session. During the relaxation session, individuals will be asked to focus on their breathing and relax as much as possible.~Then, heart rate variability, electrodermal activities and respiratory frequencies of the individuals will be measured in a sitting position for 5 minutes. In case of rest, after taking the variables, individuals will be kept to rest for 10 minutes.~After 10 minutes, the devices will be placed on the individuals again and a 2-minute relaxation session will be held.~Then, individuals will be asked to imagine running through kinesthetic imagery for 5 minutes.~Feedback will be given to individuals throughout the entire session. These feedbacks will be given verbally with an audio recording prepared by the physiotherapist.
Study: NCT04624334

Intervention type: OTHER
Intervention: EEnG Questionnaire
Description: Filling out questionnaire about EEnG procedure.

Intervention type: OTHER
Intervention: EEnG Questionnaire
Description: Filling out questionnaire about EEnG procedure.

Intervention type: OTHER
Intervention: EEnG Questionnaire
Description: Filling out questionnaire about EEnG procedure.

Intervention type: OTHER
Intervention: EEnG Questionnaire
Description: Filling out questionnaire about EEnG procedure.

Intervention type: OTHER
Intervention: Gold Standard Questionnaire
Description: Filling out questionnaire about Gold Standard diagnostic used to diagnose colonic motility disorder.

Intervention type: OTHER
Intervention: Gold Standard Questionnaire
Description: Filling out questionnaire about Gold Standard diagnostic used to diagnose colonic motility disorder.
Study: NCT04317157

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Caffeine
Description: Specific dosage of caffeine for each participant (6 mg.kg-1).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo pill.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo pill.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo pill.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo pill.
Study: NCT05302258

Intervention type: DIAGNOSTIC_TEST
Intervention: Attenuation imaging in ultrasonography
Description: Attenuation imaging in ultrasonography

Intervention type: DIAGNOSTIC_TEST
Intervention: Attenuation imaging in ultrasonography
Description: Attenuation imaging in ultrasonography
Study: NCT05920044

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: balance and proprioception training program.
Description: The program will include exercises focused on improving ankle stability and joint position sense, such as single-leg stance, wobble board, and resistance band exercises.~Participants will attend two supervised sessions per week and perform home-based exercises 3-4 times per week.~Progression of exercises will be individualized based on participant performance and tolerance.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Participants will continue their usual care, including general strength and flexibility exercises.~No specific balance and proprioception training will be provided.
Study: NCT04656106

Intervention type: DRUG
Intervention: Ryzodeg®
Description: All patients have been treated at the discretion of the treating physician in accordance with the Ryzodeg® label in South Korea. Hence independently of this study, the treating physician has determined the starting dose of Ryzodeg® as well as any dose adjustments thereafter.
Study: NCT06299722

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STEEL
Description: Relatively heavy strength training

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Circuit training
Description: Circuit training
Study: NCT05680155

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ecnoglutide
Description: Subcutaneous Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ecnoglutide
Description: Subcutaneous Injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subcutaneous Injection with matched volume

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subcutaneous Injection with matched volume
Study: NCT06028308

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartphone playing a sound
Description: A sound will be played from a portable device (smartphone mounted with earphones) during movement

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartphone playing a sound
Description: A sound will be played from a portable device (smartphone mounted with earphones) during movement