TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05833529

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Cue Exposure (VRCE) Therapy for Cocaine Craving - 2 weeks
Description: 40 10 mins VRCEs for cocaine craving (desensitization to only cocaine craving cues; no others interventions). 4 VRCE and 2 different VRCE situations by meeting. Same VRCE situations spaced intra (30 mins) and inter meetings (48 hrs). 5 standard VRCE situations (appearance and dialogues adapted to Martinique field) varying from only peers cocaine use talk to peers and participant prepare and use cocaine and ranging from the lowest to the highest participant related cocaine craving level. Situation switch to another when its initial cocaine craving level has decreased to its half for 5 continuous VRCE mins (must be ≤ 3/10; 0 = none; 10 = very high). Meetings end with relaxation/relapse prevention in any case of distress still over convenient levels. VRCE use Meta Quest 2, are visuo-auditively immersive (360°; 1st person), interactive (using virtual objects), semi-stationnary (360°-rotating stool and teleportation system). Participant skin color and cocaine using mode individualized.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Memory Focused Cognitive Therapy (MFCT) - 1 week
Description: In accordance with the Memory Focused Cognitive Therapy for Cocaine Use Disorder Therapist Guide (Marsden and Goetz, 2018), MFCT meetings will consist in 5 sequential components: Cognitive case conceptualisation of cocaine use disorder maintaining processes to inform a treatment plan; Education about cocaine's cognitive and physical effects; Cocaine related cue-induction to elicit images and affective responses; Memory reconsolidation procedures; Standard CBT techniques (e.g. behavioural experiments of cocaine-related expectancies and skills for adaptive emotion regulation).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pictures-based Cue Exposure (PCE) Therapy for Cocaine Craving - 3 weeks
Description: 60 x 10 mins PCE (desensitization to only cocaine craving cues; no others interventions). A standard audio of VRE songs is played in PCE. 4 PCE and 2 different PCE situations by meeting. Same PCE situations spaced intra (30 mins) and inter meetings (48 hrs). 5 standard PCE situations (appearance and dialogues adapted to Martinique field) varying from only peers cocaine use talk to peers and participant prepare and use cocaine and ranging from the lowest to the highest participant related cocaine craving level. Situation switch to another when its initial cocaine craving level has decreased to its half for 5 continuous PCE mins (must be ≤ 3/10; 0 = none; 10 = very high). Meetings end with relaxation/relapse prevention if any distress over convenient levels. PCE use a laptop standard PowerPoint slide show (2D pictures from VRCE; non-spatialized audio from laptop speakers), are non-interactive (seated on a stool). Participant skin color and cocaine using mode individualized.
Study: NCT06039553

Intervention type: PROCEDURE
Intervention: pulmonary artery banding
Description: Patient in this group will undergo pulmonary artery banding surgery for congenital heart disease.
Study: NCT06293521

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpotomy
Description: After the chamber is deroofed and coronal pulp is amputated using a round-end fissure bur in a high-speed handpiece with adequate water spray and light pressure until canal orifices were reached, The access cavity is flushed with sterile normal saline solution. Saline-wetted cotton pellets were placed for about 5 minutes over amputation sites applying moderate pressure to control pulpal hemorrhage. After discarding the pellets, blood oozing was present, MTA+ Cerkamed will be manipulated in the ratio of 3:1 (powder: liquid) to obtain a putty mix. This mix will be placed over the radicular pulp with the help of a suitable sterile amalgam carrier. Gentle condensation of the mix will be done in the pulp chamber with a moistened cotton pellet, followed by application of glass ionomer cement.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Partial Pulpectomy
Description: Pulp tissue extirpation is done. Biomechanical preparation is done using rotary files with frequent irrigation with Chlorhexidine. The canals are dried using sterile absorbent paper points followed by obturation by the paste of Zinc oxide and eugenol.~The tooth with then be restored with stainless steel crown
Study: NCT05093816

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Common Elements Toolbox
Description: The Common Elements Toolbox (COMET) is an online single-session intervention. It is entirely self-guided and lasts about 60 minutes. Participants complete a series of reading and writing exercises focused on four modules: cognitive restructuring, behavioral activation, gratitude, and self-compassion. The intervention is entirely unguided and completed in a single sitting.
Study: NCT05255471

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: Olaparib 300 mg, film-coated tablets, twice daily PO, d1- 28 continuously

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy drug
Description: Platinum-based chemotherapy at the Investigator's choice among the following regimens:~* Carboplatin (AUC5) plus Pegylated Liposomal Doxorubicin (PLD) 30mg/m2 on day 1 every 28 days for a maximum of 8 cycles;~* Carboplatin (AUC4) plus Gemcitabine 1000mg/m2 on day 1, 8 every 21 days for a maximum of 8 cycles;~* Carboplatin (AUC5) plus Paclitaxel (175mg/m2) every 21days for a maximum of 8 cycles
Study: NCT05895474

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Focused Ultrasound
Description: Using MRI-guided targeting, we will administer focused ultrasound in one of the 4 stimulation conditions
Study: NCT04649112

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: PBCAR19B
Description: Single dose of Allogeneic Anti-CD19 CAR T cells will be injected/infused

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: PBCAR19B
Description: Single dose of Allogeneic Anti-CD19 CAR T cells will be injected/infused

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: PBCAR19B
Description: Single dose of Allogeneic Anti-CD19 CAR T cells will be injected/infused
Study: NCT04068701

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MaNMT Biofeedback
Description: neuromuscular training intervention that incorporates biofeedback training

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: MaNMT Biofeedback
Description: neuromuscular training intervention that incorporates biofeedback training
Study: NCT06489145

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Technology-enhanced Rehabilitation
Description: Based on their individualized rehabilitation project, patients will undergo robot-assisted therapy (RAT) and/or virtual reality (VR)-based treatment.~RAT will consist of the use exoskeleton devices intended for the treatment of upper limbs (Armeo-Spring™) or for the lower limbs (Lokomat™) impairments.~VR-based rehabilitation will be conducted non-immersive VR devices: the ProKin 252™ (TechnoBody SRL, Italy), the D-Wall™ (TechnoBody SRL, Italy), and the Walker View™ (TechnoBody SRL, Italy).~Technology-enhanced treatment duration (number of sessions, minutes of use) will strictly depend on patients' rehabilitation needs and individualized rehabilitation program. Overall, part of the duration of the whole treatment will be dedicated to the use of the technological device, resulting in the same amount of rehabilitation for all participants.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Multidisciplinary Traditional Rehabiltiation
Description: Patients will receive traditional treatment consisting of two daily one-hour session (4 weeks, 20 sessions) and including rehabilitation activities like range of motion exercises (passive, active assisted and active), progressive resistive exercises, balance and strength training, and aerobic conditioning. The intervention procedures will follow the routine multidisciplinary clinical practice of the Institute where the study will be carried out. Procedures will be adapted according to patient's medical diagnosis, disability severity, and to the consequent rehabilitation objectives in favor of an individualized rehabilitation project and program. If necessary, patients might therefore undergo parallel rehabilitation activities (ie, occupational therapy, speech therapy, cognitive stimulation) that will be kept under control throughout data collection and analyses.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multidisciplinary Traditional Rehabiltiation
Description: Patients will receive traditional treatment consisting of two daily one-hour session (4 weeks, 20 sessions) and including rehabilitation activities like range of motion exercises (passive, active assisted and active), progressive resistive exercises, balance and strength training, and aerobic conditioning. The intervention procedures will follow the routine multidisciplinary clinical practice of the Institute where the study will be carried out. Procedures will be adapted according to patient's medical diagnosis, disability severity, and to the consequent rehabilitation objectives in favor of an individualized rehabilitation project and program. If necessary, patients might therefore undergo parallel rehabilitation activities (ie, occupational therapy, speech therapy, cognitive stimulation) that will be kept under control throughout data collection and analyses.
Study: NCT04712955

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bloodflow restricted exercise
Description: Low-intensity bloodflow restricted resistance exercise is conducted as traditional knee extension exercise with a load corresponding to 30% of 1 repetition maximum (RM), with concurrent partial occlusion of the circulation by means of inflatable pneumatic cuffs wrapped around the proximal part of the thighs. Cuffs are inflated to a pressure corresponding to 50% of the arterial occlusion pressure, which only compromises venous but not arterial blood flow.
Study: NCT06236971

Intervention type: BEHAVIORAL
Intervention: MRI scanning first at supine position and then turn into lateral position
Description: Magnetic resonance imaging was used to scan the upper airway of sedated subjects, first at supine position and then turn into lateral position.
Study: NCT04871841

Intervention type: BIOLOGICAL
Intervention: Sputnik V
Description: Participants will receive intramuscular (IM) injection of a single dose of rAd26-S and rAd5-S at day 0 and day 21, respectively.
Study: NCT06162988

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-NOTA-H006 is injected intravenously with a dose of 1.8 MBq[0.05MCi]/kg.
Description: 68Ga-NOTA-H006：PET imaging； 18F-FDG：PET imaging
Study: NCT04600154

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MS-20
Description: Specific fraction from fermented soy milk

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Fermented soy milk without active component
Study: NCT04802798

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fibre 1
Description: Food derived fibre presented as a white powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fibre 1
Description: Food derived fibre presented as a white powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fibre 2
Description: Food derived fibre presented as a white powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fibre 2
Description: Food derived fibre presented as a white powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Simple sugar, presented as a white powder

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Simple sugar, presented as a white powder
Study: NCT05698849

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Composition of Sports Drink
Description: The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Composition of Sports Drink
Description: The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Composition of Sports Drink
Description: The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid.
Study: NCT05467241

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-induced therapeutic tremor (SITT) combined with mindfulness
Description: SITT is a way to reduce stress by turning on a natural shaking response. This can calm the participant's body. It involves doing simple exercises. The muscles will gently shake, and release built up stress. This shaking of the muscles lets the participant's body physically let go of tension and stress.~Mindfulness is the ability to be fully present in a moment. This allows focus on what the participant is sensing and feeling in the moment. It involves the acceptance of thoughts and feelings without judging them.~Practicing mindfulness involves breathing methods, guided imagery, and other practices to relax the body and mind, help reduce stress, and not be overwhelmed by what's going on around the participant.
Study: NCT05549817

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Synchronous Exercise Program
Description: The exercise program consisted of exercises by recommended guidelines for shoulder tendinopathy patients which includes various strengthening, stretching, and proprioceptive exercises with progression.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Asynchronous Exercise Program
Description: The exercise program consisted of exercises by recommended guidelines for shoulder tendinopathy patients which includes various strengthening, stretching, and proprioceptive exercises with progression.
Study: NCT06070792

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NEURO LINGUISTIC PROGRAM
Description: NEURO LINGUISTIC PROGRAM

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PROGRESSIVE MUSCLE RELAXATION EXERCISES
Description: PROGRESSIVE MUSCLE RELAXATION EXERCISES
Study: NCT04563377

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.HTI and MVA.HTI
Description: ChAdOx1. HTI dose 5 x 10\^10 vp MVA.HTI dose 2 x 10\^8 pfu
Study: NCT04761263

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Task-oriented circuit training
Description: The task-oriented circuit training program consisted of 14 workstations. Time spent at each station will be 1.5 minutes. The children will complete the activity at one station and move to another station. The whole circuit will be completed in 21 minutes and it will be repeated twice per session with 3 minutes rest interval between the 2 circuits. Children will be encouraged to work as hard as possible at each workstation and will also be given verbal feedback and instructions aimed at improving performance. The progression of the task will be considered according to each child's ability and progressed as tolerated. Progressions include increasing the number of repetitions and increasing complexity of the exercise performed at each workstation, such as the distance reached in standing, reducing the height of the chair during sit-to stand, changing the height of blocks or by increasing speed of movement.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Selected Physical therapy program
Description: * Facilitation of balance reactions from standing position including; standing on one leg, weight shifting from standing position, stoop and recover from standing, squat from standing and standing on balance board.~* Facilitation of counterpoising mechanism through instructing the child to kick ball from standing position as well as catching and throwing ball with his hands.~* Gait training activities including: walking using different obstacles (rolls, wedges, stepper) and walking up and down stairs.~* Facilitation of protective reaction from standing position by pushing the child in different directions.~* Facilitation of rising mechanism through changing position as well as returning back to the original position e.g.: from lying to standing and from sitting to standing.~* Strengthening exercises for back and abdominal muscles as well as upper and lower limbs.~* Jumping in place and jumping a board.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Selected Physical therapy program
Description: * Facilitation of balance reactions from standing position including; standing on one leg, weight shifting from standing position, stoop and recover from standing, squat from standing and standing on balance board.~* Facilitation of counterpoising mechanism through instructing the child to kick ball from standing position as well as catching and throwing ball with his hands.~* Gait training activities including: walking using different obstacles (rolls, wedges, stepper) and walking up and down stairs.~* Facilitation of protective reaction from standing position by pushing the child in different directions.~* Facilitation of rising mechanism through changing position as well as returning back to the original position e.g.: from lying to standing and from sitting to standing.~* Strengthening exercises for back and abdominal muscles as well as upper and lower limbs.~* Jumping in place and jumping a board.
Study: NCT05515835

Intervention type: DEVICE
Intervention: body composition analysis
Description: Patients will undergo body composition analysis using bioelectical impedance method before anesthesia.
Study: NCT06302582

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs)
Description: Inject 3mL PRP+huMSCs (5 × 106) into the edge and bottom of the wound, with 0.5 ml at each point and a distance of approximately 1-3 cm between each point. Then, apply autologous PRP gel (PRP+thrombin mixture, 2ml) evenly on the wound, with a thickness of about 2mm

Intervention type: OTHER
Group type: OTHER
Intervention: Control group
Description: Standard therapy for patients with stage 3 and 4 stress injury
Study: NCT06153134

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 10% Curcuma xanthorriza Roxb.
Description: Patients in experimental arms will receive 10% Curcuma xanthorriza Roxb. cream for 2 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2% Kojic Acid
Description: Patients in experimental arms will receive 2% Kojic Acid cream for 2 months
Study: NCT05746507

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Night Respite Care
Description: (see description above)
Study: NCT05489848

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel: paclitaxel dose of 135\~175mg / m2, about 3 hours after the infusion, the use of pretreatment drugs before the infusion according to the drug instructions. Every 21 days is one session.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Paclitaxel: paclitaxel dose of 135\~175mg / m2, about 3 hours after the infusion, the use of pretreatment drugs before the infusion according to the drug instructions. Every 21 days is one session.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin: Doses were given at AUC=5 - 6 and used after paclitaxel. Based on the calculated amount, the maximum dose of carboplatin per chemotherapy does not exceed 750mg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Carboplatin: Doses were given at AUC=5 - 6 and used after paclitaxel. Based on the calculated amount, the maximum dose of carboplatin per chemotherapy does not exceed 750mg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: Concurrent cisplatin intravenous chemotherapy on radiotherapy days 1 and 29,50mg / m2, a total of 2 times.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: EBRT
Description: 50.4Gy/28 / 6 weeks; common iliac node positive or paraaortic node positive plus extended field.The radiation extension field should include the entire pelvic cavity, the common iliac vessels and the paraaortic lymph node area.The range above the extension field is determined based on the clinical status, but at least 1-2cm above the renal vascular level.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: VBT
Description: Subnormal vaginal mucosa was 0.5cm, 30Gy / 5times /5weeks.