TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06166667

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fecal Microbiota Transplant（FMT）
Description: Patients involved in the trial received 20 capsules of Enterobacteriaceae (one course) on days 1, 8, and 15, which were provided by Dongyuan Yikang company. Patients were prohibited from taking antibiotics such as amoxicillin and Cefalexin during the trial.
Study: NCT04946006

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin will be prepared in a 1L bag of Ringer's lactate, to be infused at a rate of 125 ml/h.
Study: NCT06247020

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Supplementation with sodium- butyrrate
Description: Oral supplementation with sodium butyrrate capsules

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral supplementation with placebo capsules
Study: NCT04932577

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Faecal microbiota transplantation
Description: All participant will receive three applications of either FMT or placebo and afterwards followed for 1 year.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06632665

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: transcutaneous vagus nerve stimulation+virtual reality+routine physical therapy
Description: Transcutaneous vagus nerve stimulation Location The left auricular branch vagus nerve will be stimulated by the modified dot -like electrodes will be fitted to the cymba conchae.frequency:Stimulation perform for 30 minutes per day for 4 weeks .~duration 600 pulses (intratrain pulse) frequency =20 Hz ; Pulse duration =0.3ms ,lasting 30 seconds each time ,stimulating once every 5 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: transcutaneous vagus nerve stimulation+routine physical therapy
Description: Transcutaneous vagus nerve stimulation Location The left auricular branch vagus nerve will be stimulated by the modified dot -like electrodes will be fitted to the cymba conchae.Stimulation perform for 30 minutes per day for 4 weeks .~Routine physical therapy Stretching Areas :upper chest ,neck flexors ,shoulder flexor and adductors ,elbow and wrist flexors 10 minute per session,and stretches will held for 10s -30swith four repetition of each.30 minutes per day for 4 weeks Upper extremity Proprioception ,coordination,speed and agility increase such as followReach and grasp Handle turning simulated eating task Inserting object Opening bottle strenghtening exercise Muscles biceps brachii brachialis Coracobrachialis triceps brachii wrist extensors 10 minute per session for 4 weeks
Study: NCT06224465

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: aerobic exercises
Description: Antiaging diet instruction :Be aware of the amount of calories, Reduce overall fat and sugar intake, Drink at least 10 glasses of water every day in order to remain healthy.~d. Eat a variety of complex carbohydrates and vegetables instead of bread, rice, and corn.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aerobic exercises
Description: Antiaging diet instruction :Be aware of the amount of calories, Reduce overall fat and sugar intake, Drink at least 10 glasses of water every day in order to remain healthy.~d. Eat a variety of complex carbohydrates and vegetables instead of bread, rice, and corn.
Study: NCT04916444

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: rTMS
Description: repetitive transcranial magnetic stimulation is a painless, noninvasive form of neurostimulation. This study uses an accelerated protocol in which the neurostimulation pulses are delivered in 4 sessions per day over 4 consecutive days (16 total sessions). Active or sham rTMS will be provided at 9 weeks following botox injections.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: rTMS
Description: repetitive transcranial magnetic stimulation is a painless, noninvasive form of neurostimulation. This study uses an accelerated protocol in which the neurostimulation pulses are delivered in 4 sessions per day over 4 consecutive days (16 total sessions). Active or sham rTMS will be provided at 9 weeks following botox injections.
Study: NCT06574360

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S1RA plus NMDAE
Description: Use of an S1R agonist plus an NMDA enhancer for the treatment of treatment-resistant schizophrenia.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: S1RA plus Placebo Cap
Description: Use of an S1R agonist plus placebo as a comparator
Study: NCT04709211

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Facia Iliaca block
Description: patients will receive Ultrasound-guided Facia Iliaca block using 50 ml 0f Bupivacaine 0.25%

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anterior Quadratus Lumbroum block
Description: patients will receive Ultrasound-guided Anterior Quadratus Lumbroum block using 50 ml 0f Bupivacaine 0.25%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine
Description: bupivacaine
Study: NCT05347212

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given by IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Relatlimab
Description: Given by IV
Study: NCT05831020

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: VAC and bolster dressing
Description: Bolster dressing- Moist bulky cotton gauze dressing and wrapped with cotton bandage.~Vacuum assisted closure (VAC) dressing- A fenestrated tube placed between two sheets of sterilized foam secured to the surrounding skin using adhesive dressing (OPSITE).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: VAC and bolster dressing
Description: Bolster dressing- Moist bulky cotton gauze dressing and wrapped with cotton bandage.~Vacuum assisted closure (VAC) dressing- A fenestrated tube placed between two sheets of sterilized foam secured to the surrounding skin using adhesive dressing (OPSITE).
Study: NCT05607979

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lavior Diabetic Wound Gel
Description: Daily application of hydrogel treatment for 60 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Smith & Nephew Solosite Gel Hydrogel Wound Dressing
Description: Daily application of hydrogel treatment for 60 days.
Study: NCT05280132

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Personalized antibiotic treatment
Description: Personalized antibiotic treatment based on mPCR results, PCT (values and kinetics) and appearance of sputum.

Intervention type: OTHER
Group type: OTHER
Intervention: Usual antibiotic treatment
Description: The antimicrobial therapy is left at the discretion of the physicians, as in usual practice.
Study: NCT04942158

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non-instrumentation technique with use of CTZ paste
Description: After local anesthesia and rubber dam isolation, the pulp chamber will be accessed. After the location of root canals entrance, an initial irrigation will be conducted using 1% sodium hypochlorite. Then, a paste containing two antibiotics (chloramphenicol and tetracycline) and zinc oxide and eugenol (CTZ paste) will be placed in the pulp chamber floor, into the root canal entrances. Then, a layer of glass ionomer cement will be placed, and the teeth will be restored with bulk-fil resin composite.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Instrumentation technique and filling with Zinc Oxide and Eugenol paste
Description: After anesthesia and rubber dam isolation, pulp chamber will be accessed with burs, and the root canals entrance will be prepared using a Gates Glidden bur. The root canal length determination will be done subtracting 1 mm from the radiographic measurements performed on the different roots. The instrumentation will be performed with 21mm stainless steel endodontic hand K-files, with International Organization for Standardization (ISO) tip ranging from #08 to #35. Irrigation will be performed using 1% sodium hypochlorite. After the last file, a final irrigation will be conducted with ethylenediaminetetraacetic acid and tegentol (EDTA-T) and 0.9% sodium chloride solution, and the root canals will be dried with paper points. Then, the root canals will be filled with a Zinc Oxide and Eugenol paste (ZOE paste), inserted into the root canals with a lentulo spiral. A layer of glass ionomer cement will be placed, and the teeth will be restored with bulk-fil resin composite.
Study: NCT05193643

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sonovein Treatment
Description: The Sonovein System provides High Intensity Focused Ultrasound (HIFU) ablation of soft tissue. The energy is delivered via an extra-corporeal treatment probe, which includes an imaging system. The high-energy ultrasound waves propagate through the skin and are focused on a portion of the target tissue, generating intense heat and causing local cell apoptosis and progressive tissue volume reduction over the following months in the tissue within the focal area. The process is then repeated in a stepwise fashion to destroy the targeted tissues.
Study: NCT06050161

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Articulating laparoscopic instrument
Description: The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Articulating laparoscopic instrument
Description: The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Articulating laparoscopic instrument
Description: The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional laparoscopic instrument
Description: Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional laparoscopic instrument
Description: Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional laparoscopic instrument
Description: Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robotic surgical instrument
Description: Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Robotic surgical instrument
Description: Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Robotic surgical instrument
Description: Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study: NCT06130553

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD3470
Description: AZD3470 is a novel, potent and selective, second-generation, MTAP-selective, inhibitor of PRMT5.
Study: NCT05911269

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TiMBRe
Description: 1 \& 2 Music Listening~* Live music played by the music therapist (e.g., guitar, voice) and AYA selected music will be used to facilitate attention to the present moment and provide cues for breathing/relaxation.~  3 \& 4 Music Facilitated Breathing~* The therapist will lead participants in music facilitated breathing exercises using rhythmic features of the music to cue structured breathing for relaxation and self-awareness~  5 \& 6 Music Facilitated Progressive Muscle Relaxation for Stress Reduction~* Using music as a structured auditory cue for tensing and releasing of muscles.~  7 \& 8 Body Percussion~* The therapist will lead participants in a hands-on body percussion activity to bring attention to the sound of rhythm, sensation in their hands and body.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Standard of care study staff calls and cancer survivorship resources
Study: NCT04506879

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Popliteal Sciatic nerve block
Description: Patients schedule for lower limb surgery under regional anesthesia will receive ultrasound guided subparaneural popliteal sciatic nerve block. After identification of the common peroneal nerve and tibial nerve, local anesthetic agents will be injected close to each nerve below the point of divergence at the popliteal fossa. The spread of the drug and the sensory and motor function of that limb will be assessed regularly till it is ready for surgery.
Study: NCT05974891

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilot application
Description: Pilot application will be carried out with at least 10 students. A pre-test will be applied to the experimental group. After the scales are applied, the experiment will be applied to the experimental group with the Geriatric Medication Game simulation.~Students simulating the elderly patient role during this simulation will gain a better understanding of age-related health problems and how older adults feel when confronting them. After the application, debriefing, which is the last stage of the simulation training, will be done to evaluate the application. After the application and analysis session is completed, the post-test will be applied to the experimental group. A 3-week clinical practice will be planned for the students in the experimental groups in order to evaluate the continuation of the acquired skills and acquired awareness. In this application, students will be asked to care for the elderly patient and the pre-test will be repeated at the end of the application.
Study: NCT06437548

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percutaneous spinal cord stimulation
Description: The parameters of percutaneous cervical spinal cord stimulation leads will be adjusted for optimal upper extremity motor function.
Study: NCT05498025

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deterra activated charcoal pouch
Description: drug disposal pouch
Study: NCT06082349

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lymphaticovenous anastomosis
Description: Lymphaticovenous anastomosis (LVA) involves connecting a lymphatic vessel to a adjacent vein of similar size, thereby facilitating the ouflow of lymphatic fluid in patients suffering from secondary lymphedema

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham surgery
Description: Sham surgery involves the process of surgery, including local anesthesia and incisions, but no LVA is made.
Study: NCT06104891

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Recharge Placebo Control 1
Description: Participants will use their Radicle Recharge Placebo Control 1 as directed for a period of 5 hours.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Recharge Active Study Product 1
Description: Participants will use their Radicle Recharge Active Study Product 1 as directed for a period of 5 hours.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Recharge Active Study Product 2
Description: Participants will use their Radicle Recharge Active Study Product 2 as directed for a period of 5 hours.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Recharge Active Study Product 3
Description: Participants will use their Radicle Recharge Active Study Product 3 as directed for a period of 5 hours.
Study: NCT05467605

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: probiotics( Lactobacillus acidophilus, lactobacillus delbruekii and lactobacillus fermentum 10 billions),
Description: therapeutic intervention, Children will be randomized into two groups using sealed envelopes on admission after meeting inclusion criteria, group ONE will receive multi strain probiotic product which contains(Lactobacillus acidophilus, lactobacillus delbruekii and lactobacillus fermentum 10 billions),

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: maltose dissolved in distilled water
Description: the other group placebo (GROUP TWO ) will receive maltose dissolved in 10 ml distilled water .
Study: NCT04976478

Intervention type: DRUG
Intervention: Nimotuzumab
Description: Patients receive Nimotuzumab: 200mg, intravenous infusion, weekly for 6 weeks.

Intervention type: RADIATION
Intervention: EBRT combined with brachytherapy
Description: IMRT/VMAT are adopted. A total dose of 45-50.4 Gy, 1.8\~2.0Gy/f, 25\~ 28F in pelvic and/or extension filed. For patients with metastasis in pelvic lymph node and abdominal para-aortic lymph node, the dose of radiation in local lesion will be increased to 60\~66Gy. For patients at stage IIIB, concurrent radiation will be given in parametrial extension or in the late course the dose will be increased to 60Gy.~Brachytherapy: Three dimensional high dose rate brachytherapy is used with HR-CTV D90 cumulative dose of 80\~85Gy (EQD2); If the tumor diameter is ≥4cm, HR-CTV D90 cumulative dose is ≥87Gy (EQD2). Brachytherapy combined with external beam radiotherapy will be completed within 8 weeks.
Study: NCT05486507

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Montmorency tart cherry
Description: US grown Montmorency tart cherry 60ml per day for 6 weeks.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Taste matched placebo.
Study: NCT05267743

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegoprazan 50mg QD
Description: Tegoprazan 50mg tablets will be orally administered, once daily, for up to 2 weeks or 4 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lansoprazole 30mg QD
Description: Lansoprazole 30mg tablets will be orally administered, once daily, for up to 2 weeks or 4 weeks.
Study: NCT05280730

Intervention type: OTHER
Intervention: No intervention
Description: There is no intervention
Study: NCT06324851

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drospirenone / Estetrol
Description: Endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Drospirenone/Estetrol at any time of the menstrual cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nomegestrol Acetate / Estradiol
Description: Endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Nomegestrol Acetate/Estradiol at any time of the menstrual cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethinylestradiol / Dienogest
Description: Endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Ethinylestradiol/Dienogest at any time of the menstrual cycle
Study: NCT04880824

Intervention type: BEHAVIORAL
Intervention: Prehabilitation- new form of care
Description: The participants in the intervention group take part in a shared decision-making (SDM) conference to plan the intervention. The therapeutic content of the prehabilitation is defined individually for each patient in the SDM conference. Prehabilitation will be a structured and individually tailored 3-week program.
Study: NCT06168279

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: hand occlusal articulation
Description: The upper and lower cast will be scanning separately then will be articulated manually in the final occlusion then scanned after that the stl file will insert to the software to complete virtual planning of orthognathic surgery to made splints that will be using in the operation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: digital occlusal articulation
Description: Both upper and lower casts will be scanning separately, then the 3D casts will be articulating by using 3d virtual program to obtained the final occlusion after that the stl file will insert to the software to complete virtual planning of orthognathic surgery to made splints that will be using in the operation
Study: NCT06532136

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Deucravacitinib
Description: Deucravacitinib 6 mg orally once daily.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Deucravacitinib
Description: Deucravacitinib 6 mg orally once daily.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Matching placebo orally once daily.
Study: NCT05977335

Intervention type: DIAGNOSTIC_TEST
Intervention: Autonomic Function Testing
Description: Autonomic Function Testing (AFT) includes Valsalva Manoever, Deep Breathing Test, and Head-up Tilt Table Testing.