TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06329713

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group I: 30 Min Interval Time
Description: 10 ml of a solution containing 0,1% of bupivacaine and 2 mcg/ml fentanyl through the epidural cathether, maintained by programmed intermittant epidural (PIE) boluses of 7,5 ml of the same solution once in every 30 minutes, starting 1 hour after the loading dose. patient controlled epidural analgesia (PCEA) will be programmed so that 8 ml of the same solution with a lock-time of 15 minuts may be administered

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group II: 60 Min Interval Time
Description: 10 ml of a solution containing 0,1% of bupivacaine and 2 mcg/ml fentanyl through the epidural cathether, maintained by programmed intermittant epidural (PIE) boluses of 15 ml of the same solution once in every hour, starting 1 hour after the loading dose. patient controlled epidural analgesia (PCEA) will be programme
Study: NCT05977803

Intervention type: RADIATION
Group type: OTHER
Intervention: MRI with CEST sequence, IVIM and ASL sequence
Description: Three sequences will be added as part of the protocol (for an additional duration of about 10 minutes) :~* The CEST sequence~* The ASL infusion sequence~* The IVIM sequence
Study: NCT05953272

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EMG Biofeedback therapy and Bobath therapy
Description: EMG Biofeedback therapy will be used to up-train the ankle dorsiflexors in stroke patients. It will be given for 15 minutes. Patient will practice 2 blocks of Tibialis Anterior muscle contraction trials (holding for 10 seconds per trial with 10 seconds of rest, 20 trials per block with 1 minute 40 seconds of rest in between the blocks) with the heel contacts the floor for a total of 40 trials.~In Bobath therapy, we will use exercises as per Bobath guidelines for management of stroke patients to improve the lower extremity function, balance and gait ability. All of the exercises will be performed for 10 repetitions in each session.~Patient will also perform a set of Home Exercise Program given to them for once daily in their home during the treatment period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bobath therapy
Description: In Bobath therapy, we will use exercises as per Bobath guidelines for management of stroke patients to improve the lower extremity function, balance and gait ability. All of the exercises will be performed for 10 repetitions in each session.~Patient will also perform a set of Home Exercise Program given to them for once daily in their home during the treatment period.
Study: NCT05021380

Intervention type: OTHER
Intervention: GROUP
Description: Non-invasive diagnosis of dental pain, dental root canal treatment, salivary specimen collection from the first visit to next and the last during 4 weeks of dental care
Study: NCT06135454

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Open Wedge High Tibial Osteotomy
Description: For OWHTO,The osteotomy plane, directed from 30 to 35 mm distal to the medial tibial plateau to 10-15 mm distal to the lateral tibial plateau in the coronal plane, was marked by two Kirschner wires with threaded tips. A transverse osteotomy was performed, leaving the lateral cortex intact as a hinge. After the ascending osteotomy and opening. The medial opening gap was filled with two β-TCP wedges and fixed with a TomoFix anatomical plate and locking screws .

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Open Wedge High Tibial Osteotomy
Description: For OWHTO,The osteotomy plane, directed from 30 to 35 mm distal to the medial tibial plateau to 10-15 mm distal to the lateral tibial plateau in the coronal plane, was marked by two Kirschner wires with threaded tips. A transverse osteotomy was performed, leaving the lateral cortex intact as a hinge. After the ascending osteotomy and opening. The medial opening gap was filled with two β-TCP wedges and fixed with a TomoFix anatomical plate and locking screws .

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Double Level Osteotomy
Description: The DLO was started from a lateral DFO. A 5-6-cm incision was made proximally at the distal femur from the lateral femoral epicondyle.Two Kirschner wires with threaded tips were inserted to make a length between the wires that was preoperatively planned as the lateral closed osteotomy. Transverse and ascending osteotomies were performed using a Precision Oscillating Tip Saw. The gap was closed and fixed using a TomoFix medial distal femur anatomical plate , which was bent for the lateral distal femur. The subsequent OWHTO was performed as described above.
Study: NCT05375240

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Propranolol will be given at a dose of 10 mg orally, 3 times per day, for 7 consecutive days after stroke onset.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Propranolol will be given at a dose of 10 mg orally, 3 times per day, for 7 consecutive days after stroke onset.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ceftriaxone
Description: Intravenously 2.0g/day for 7 consecutive days.
Study: NCT05326204

Intervention type: OTHER
Intervention: Home blood glucose monitoring
Description: Self monitoring of capillary blood glucose

Intervention type: OTHER
Intervention: Home blood glucose monitoring
Description: Self monitoring of capillary blood glucose
Study: NCT05068427

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chidamide
Description: 20mg or 30mg orally twice per week(BIW)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envafolimab
Description: 400mg subcutaneous infusions every 4 weeks
Study: NCT05338944

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialectical behavioral therapy
Description: Working with psychologists through DBT skills training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle
Description: Working with kinesiologist and registered dietician to improve lifestyle habits.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle
Description: Working with kinesiologist and registered dietician to improve lifestyle habits.
Study: NCT06145217

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPRYCEL® (dasatinib) 100 mg Film-Coated Tablets in combination with Omeprazole Delayed-Release Capsules USP, 40 mg
Description: To evaluate the drug-drug interaction between SPRYCEL® 100 mg and Omeprazole under fasted conditions in healthy, adult, human subjects.
Study: NCT04410913

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin plus Visual Healing Set and Setting
Description: Psychedelic session (psilocybin 25 mg) with a therapist who will guide and accompany participants before, during, and after the psychedelic session. In addition, participants will have the chance to view nature-themed videos before and after the psychedelic sessions. Four weeks later, a second psychedelic session (psilocybin 25 mg) with either Visual Healing or standard Set and Setting procedures (patient's choice).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin plus Standard Set and Setting
Description: Psychedelic session (psilocybin 25 mg) with a therapist will guide and accompany participants before, during, and after the psychedelic session. Four weeks later, a second psychedelic session (psilocybin 25 mg) with either Visual Healing or standard Set and Setting procedures (patient's choice).
Study: NCT01780207

Intervention type: DEVICE
Group type: OTHER
Intervention: PFO Closure
Study: NCT04720898

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LUNA-EMG
Description: The LUNA-EMG (Samcom) system is a robot that allows the evaluation of muscular strength through the recording of muscle activity (electromyography - EMG) in order to provide precise objective data on the patient's muscle function. In addition to the diagnostic aspect (evaluation of muscle strength, range of motion and proprioception), the LUNA-EMG robot provides optimized range of motion's movements and a visual feedback on the patient's performance. In addition, it may enhance neuroplasticity due to the increased number of movements repetitions which could influence motor learning.
Study: NCT05467072

Intervention type: DEVICE
Intervention: Annular closure
Description: Lumbar discectomy patients treated with Annular Closure Device BARRICAID
Study: NCT05905861

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Skin incision with scalpel.
Description: A Pfannenstiel skin incision will be performed using a scalpel, extending through the subcutaneous tissue and rectus sheath. After separation of rectus muscles, peritoneum will be visualized and opened. Optimal hemostasis will be achieved by applying pressure to skin blood vessels and ligating any subcutaneous bleeding.~Group A: skin incision with a scalpel.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Skin incision with a diathermy.
Description: A Pfannenstiel skin incision will be made using a scalpel. Subsequently, a diathermy pen electrode will be employed for the dissection of deeper tissues.~Optimal hemostasis will be achieved by using the same blade pen electrode, set to coagulation mode.~Group B: skin incision with diathermy.
Study: NCT06153394

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Redesca (enoxaparin sodium for injection)
Description: Redesca is low molecular weight heparin and a biosimilar biologic drug (biosimilar) to Lovenox. Indications have been granted on the basis of similarity between Redesca and the reference biologic drug Lovenox. As such, Redesca (enoxaparin sodium) is indicated for thromboprophylaxis in patients undergoing high risk abdominal and colorectal surgeries. Doses are provided as self-administered subcutaneous injections using a pre-filled syringe with a protective shield.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fragmin (dalteparin)
Description: Fragmin is a low molecular weight heparin indicated for thromboprophylaxis in patients undergoing high risk abdominal and colorectal surgeries. Doses are provided as self-administered subcutaneous injections using a pre-filled syringe with a protective shield. Our institution uses this drug for standard of care thromboprophylaxis (30 days) in this patient population.
Study: NCT05933772

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens A (comfilcon A toric lens)
Description: One month wear

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens A (comfilcon A toric lens)
Description: One month wear

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens B (lehfilcon A toric lens)
Description: One month wear

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens B (lehfilcon A toric lens)
Description: One month wear
Study: NCT05455840

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Da Vinci SP surgical platform
Description: using Da Vinci SP platform in thymothymectomy or extended thymectomy
Study: NCT05690906

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ReSpace™
Description: The experimental group subjects will be injected with ReSpace™ hydrogel.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: gauze packing
Description: The subjects of both groups will be given gauze packing

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: gauze packing
Description: The subjects of both groups will be given gauze packing
Study: NCT05817422

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: cAd3-Marburg vaccine
Description: The recombinant chimpanzee adenovirus Type 3-vectored Marburg vaccine, (cAd3-Marburg) is composed of a cAd3 vector that expresses Marburg wild type glycoprotein (WT GP) from the Angola strain.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% NaCl solution for injection.
Study: NCT04585386

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual analog scale
Description: to measure the lumbar and radicular pain felt by the patient.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Visual analog scale
Description: to measure the lumbar and radicular pain felt by the patient.
Study: NCT05018468

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ventilation
Description: Patients in group 1 undergo ventilation with an anatomical facial mask and 100% oxygen for three minutes. Patients in group 2 undergo ventilation with a nasal mask and 100% oxygen for three minutes. In both groups, ventilation will be performed with the controlled mode of the anesthesia machine with a volume of 8 cc/kg and a speed of 12-20/min.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ventilation
Description: Patients in group 1 undergo ventilation with an anatomical facial mask and 100% oxygen for three minutes. Patients in group 2 undergo ventilation with a nasal mask and 100% oxygen for three minutes. In both groups, ventilation will be performed with the controlled mode of the anesthesia machine with a volume of 8 cc/kg and a speed of 12-20/min.
Study: NCT06356415

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine injection
Description: Group one will receive infraclavicular block using bupivacaine

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine+ Dexamethasone+ Dexmedetomidine
Description: Group two will receive infraclavicular block using dexamethasone and dexmedetomidine added to the bupivacaine
Study: NCT04585386

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mac Gill Pain Questionnaire
Description: self-questionnaire that allows a qualitative assessment of chronic pain
Study: NCT05258981

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: MRI
Description: Brain MRI
Study: NCT04459442

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Umbilical cord clamping at birth.
Description: Umbilical cord clamping after delivery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Umbilical cord clamping at birth.
Description: Umbilical cord clamping after delivery.
Study: NCT04585386

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mac Gill Pain Questionnaire
Description: self-questionnaire that allows a qualitative assessment of chronic pain

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Roland and Morris Disability Questionnaire
Description: functional disability scale for assessing low back pain

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Roland and Morris Disability Questionnaire
Description: functional disability scale for assessing low back pain

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quebec questionnaire
Description: To access the patient's perception of incapacity

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quebec questionnaire
Description: To access the patient's perception of incapacity
Study: NCT04750148

Intervention type: DIAGNOSTIC_TEST
Intervention: 6-minute walking test
Description: The subject walks as far as possible for 6 minutes along a 30m long corridor.

Intervention type: DIAGNOSTIC_TEST
Intervention: 2-minute walking test
Description: The subject walks as far as possible for 2 minutes along a 30m long corridor.

Intervention type: DIAGNOSTIC_TEST
Intervention: 10-meter walk test
Description: The natural and fast walking speeds of the subject are measured over 10m. This speed is measured by the examiner as well as by the subject (self-tested version).

Intervention type: DIAGNOSTIC_TEST
Intervention: One leg stance test
Description: The time held in unipodal equilibrium is measured by the examiner.
Study: NCT05529303

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Such as art therapy, play therapy, breathing techniques
Description: The Cognitive Behavioral Therapy (CBT) model suggests that the individual's dysfunctional thoughts about self, the world, and/or others are based on irrational or illogical assumptions. An individual's self and his/her view of the world are central to the determination of his/her feelings and behaviors and thus can be changed through changing the individual's thoughts, feelings, and behaviors. CBT techniques are in line with the use of expressive art techniques. The common goal in both CBT and expressive arts is to achieve behavior change in the individual. An intervention program has been prepared by the researcher in line with this literature information.
Study: NCT05949008

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin Extended Release (ER) Oral Tablet
Description: Metformin ER will be provided as 1000 mg capsules by Qingdao Baheal Pharmaceutical Co., Ltd. In addition to the active ingredient metformin HCl,each tablet contains the following inactive ingredients: Povidone, Sodium Lauryl Sulfate, Magnesium Stearate, Cellulose Acetate, Polyethylene Glycol (PEG 400, PEG 8000), Triacetin, Hypromellose, Titanium Dioxide, Polysorbate 80, Ferrosoferric Oxide, Shellac.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo will be provided as 1000 mg capsules
Study: NCT06304376

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Alveolar ridge grafting
Description: Alveolar ridge grafting was carried out using anterior iliac crest bone graft. Khoury shell technique was the method of ridge reconstruction via a cortical bone shell was fixed away from alveolar ridge using two micro-screws and the gap created was filled by cancellous bone
Study: NCT05333536

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental: Experimental group exercises
Description: Experimental performs Strengthening exercises of core.10 reps , 3 sets of each.Prone plank(10 sec hold)(18) ,Side plank (8 sec hold),Bridging (8 sec hold)(19),Bird dog (10 reps ,3 sets),Leg drop (10 reps, 3 sets)(15),Dying bug with their regular swimming practice. First 2 weeks simple strengthening exercises.Next 4 weeks stability ball exercises. Dying bug without stability ball. And strengthening exercises of Upper Limb and Lower Limb with theraband ,10 reps each.Upper Limb: Latissimus dorsi,Serratus anterior, Upper trapezius.Lower limb : Flexors of hip, Extensors of hip,Plantar flexors.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No Intervention: Control group
Description: control only participates in their yearly swimming trainings.
Study: NCT06075498

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: transversus abdominis plane block,
Description: 2 different plan blocks; 1. transversus plane block 2. quadratus lumborum plane block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: transversus abdominis plane block,
Description: 2 different plan blocks; 1. transversus plane block 2. quadratus lumborum plane block
Study: NCT05305053

Intervention type: OTHER
Intervention: preoperative MDT discussion
Description: high-risk patients are subjected to an MDT discussion among care providers
Study: NCT05891470

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MonaLisa Touch device
Description: sessions with intra-vaginal CO2 laster system

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal dilatators
Description: Home use of vaginal dilatators (at least twice a week for minimum 5 minutes)
Study: NCT05442125

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Using DNA methylome to select embryos
Description: DNA methylation level Embryo with methylation level closest to the optimal level (from one couple patients) is the one for embryonic transfer to uterus

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Using morphologic score to select embryos
Description: blastocyst will transferred according to morphologic score or blastocysts will be biopsied on trophectoderm, sequenced with next-generation sequencing (NGS). Euploidy will transferred one by one according to morphologic score.
Study: NCT05846269

Intervention type: OTHER
Intervention: Educational Intervention
Description: Educational intervention addressing trauma-informed care and resiliency.
Study: NCT06213415

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Corticosteroid
Description: Oral steroids plus intratympanic injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Corticosteroid
Description: Oral steroids plus intratympanic injection
Study: NCT04236531

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Cognitive tests and neuroimaging
Description: comparison of cognitive performances and brain anatomy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive tests and neuroimaging
Description: comparison of cognitive performances and brain anatomy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive tests and neuroimaging
Description: comparison of cognitive performances and brain anatomy
Study: NCT05905679

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary Supplement: Probiotics
Description: 6 Billion CFU

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Dietary Supplement: Placebo
Description: 0 CFU per day
Study: NCT05525286

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOT102
Description: SOT102 is an antibody-drug conjugate (ADC) targeting CLDN18.2 with the anthracycline PNU as cytotoxic moiety.
Study: NCT05854394

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimodal prehabilitation management Multimodal prehabilitation management
Description: Multimodal prehabilitation strategy includes physical exercise (moderate aerobic exercise combined with resistance exercise ), nutritional suggestion and optimization（whey protein supplement）, and psychological therapy, as well as conventional guidance (including drug treatment recommendations for chronic disease, quit smoking and abstinence).
Study: NCT04927416

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68-Gallium-DOTATATE-PET/CT
Description: 68Ga-DOTATATE is administered one-time via intravenous injection of 5 mCi in a volume of 3-5 ml containing up to 50 mcg \[68Ga\] DOTATATE.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68-Gallium-DOTATATE-PET/CT
Description: 68Ga-DOTATATE is administered one-time via intravenous injection of 5 mCi in a volume of 3-5 ml containing up to 50 mcg \[68Ga\] DOTATATE.
Study: NCT06000046

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automatic image analysis
Description: After referral for suspected prostate cancer, the patient is scanned with magnetic resonance imaging (MRI) in accordance with guidelines of the standardized healthcare pathway. For consenting patients, the images are interpreted in two ways: first, in the conventional manner, i.e., manually by a radiologist, to determine whether clinically significant cancer is suspected. If so, the radiologist will delineate the suspicious lesions. In the second approach, the software will perform the same task as the radiologist, but automatically. If either or both interpretations point to significant cancer, the patient will be sent for targeted biopsy sampling. Histopathologic evaluation of the samples will then determine whether significant cancer is present in each of the targeted lesions (delineated by the radiologist, software, or both).