TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05231694

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo injection
Description: The patients will receive 1ml volume of physiological saline (PS) injected into the gluteal muscle, once a day for 4 weeks.

Intervention type: DEVICE
Group type: OTHER
Intervention: EA intervention
Description: Patients take supine position. After skin disinfection with 75% ethanol routine disinfection, the stainless needle (size 0.25mm×40mm, Hua Tuo brand, Suzhou Medical Supplies Company Ltd in Jiangsu, China) will be inserted in GV20（Baihui) and the stainless needle(size 0.25mm×25mm, described above) will be inserted in GV26 (Shuigou), acupoints will be stimulated manually until patients feel soreness, distension or heaviness (the reaction of De Qi). Then, the needles are stimulated by using an acupuncture point nerve stimulator (HANS-200, Nanjing Jinsheng, Ltd., China) with a frequency of 2/100 Hz and an intensity of 3 mA for 40 min (a homemade relay cycled power to the electrode for 6 sec on and 6 sec off), 28 days as a course of treatment, once a day.

Intervention type: DEVICE
Group type: OTHER
Intervention: EA intervention
Description: Patients take supine position. After skin disinfection with 75% ethanol routine disinfection, the stainless needle (size 0.25mm×40mm, Hua Tuo brand, Suzhou Medical Supplies Company Ltd in Jiangsu, China) will be inserted in GV20（Baihui) and the stainless needle(size 0.25mm×25mm, described above) will be inserted in GV26 (Shuigou), acupoints will be stimulated manually until patients feel soreness, distension or heaviness (the reaction of De Qi). Then, the needles are stimulated by using an acupuncture point nerve stimulator (HANS-200, Nanjing Jinsheng, Ltd., China) with a frequency of 2/100 Hz and an intensity of 3 mA for 40 min (a homemade relay cycled power to the electrode for 6 sec on and 6 sec off), 28 days as a course of treatment, once a day.

Intervention type: DEVICE
Group type: OTHER
Intervention: sham EA intervention
Description: The only difference between sham EA intervention and EA intervention is that the stimulator is connected to the needle handle without power for 40 min intervention.

Intervention type: DEVICE
Group type: OTHER
Intervention: sham EA intervention
Description: The only difference between sham EA intervention and EA intervention is that the stimulator is connected to the needle handle without power for 40 min intervention.
Study: NCT04976309

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lu AG09222
Description: Single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Single dose
Study: NCT04714554

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Relugolix/E2/NETA FDC
Description: Relugolix/E2/NETA (40 mg/1 mg/0.5 mg) FDC tablet; oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Relugolix
Description: Relugolix 120-mg tablets; oral administration.
Study: NCT06022965

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supportive Care
Description: Receive GA-based interventions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telemedicine
Description: Receive GA-based interventions via telemedicine
Study: NCT05677100

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aortix System
Description: Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and are resistant to diuretic therapy.
Study: NCT04714554

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Erythromycin
Description: Erythromycin 500-mg tablets; oral administration.
Study: NCT05248022

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Drug-eluting beads bronchial arterial chemoembolization
Description: Drug-eluting beads bronchial arterial chemoembolization generally uses platinum-containing two-drug chemotherapy platinum (cisplatin, carboplatin, nedaplatin) combined treatment, and drug-loaded microspheres can be loaded with vinorelbine, gemcitabine, irinote Kang, raltitrexed. The dose of chemotherapy drugs is set to 75mg/m2 of platinum, and the dose of chemotherapy through catheter infusion is reduced by 25%. The dose of drug-loaded drugs is vinorelbine 25mg/m2, gemcitabine generally 1000mg/m2, irinotecan 80mg/ m2, raltitrexed 4mg. Chemotherapy was perfused first, followed by embolization with drug-loaded microspheres, until the blood flow in the artery supplying the tumor slowed down and approached stagnation. The number of DEB-BACE treatments is determined by the investigator, and is given as needed according to the patient's condition, usually 1-2 times, with an interval of 28±10 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Programmed Cell Death Protein 1 Inhibitor
Description: Programmed cell death protein 1 inhibitor fixation was treated with sintilimab (Xinda Biopharmaceutical Co., Ltd.). It is administered by intravenous infusion, and the recommended dose is 200 mg, given once every 21 days. The medication will last for two years until disease progression or intolerable toxicity occurs. During immunotherapy, immunosuppressive agents will not be replaced and the dose will not be adjusted.
Study: NCT06033521

Intervention type: DRUG
Intervention: Menopausal hormone therapy Intervention Type: Drug
Description: Subjects who were newly diagnosed menopausal symptoms between 01 Jan 2012 and 31 Dec 2019, and were followed up for 12 months at least in the HIRA claims database
Study: NCT05678894

Intervention type: OTHER
Group type: OTHER
Intervention: Scanner and EOS imaging
Description: Cross-sectional imaging and 3D reconstruction to measure and compare acetabular anteversion in 4 functional pelvic positions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scanner and EOS imaging
Description: Cross-sectional imaging and 3D reconstruction to measure and compare acetabular anteversion in 4 functional pelvic positions.
Study: NCT05977582

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Spanish version eBodyProject
Description: The Spanish adaptation of the eBodyProject program will be modified (Stice et al., 2012b). This program consists of 4 modules adapted from the most recent version of the original program The Body Project, presented by the original authors who have given their consent and suggestions for the realization of the Spanish version.~The activities proposed through the different modules will be in written format or behavioral activities aimed at criticizing the ideal of feminine beauty imposed by today's society and promoting self-acceptance.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychoeducationa Prevention Program
Description: Participants in this group will receive a weekly newsletter with information about the beauty ideal, the costs of pursuing it, and tips for resisting the pressure to pursue this ideal, as well as tips for managing the emotions associated with it. However, they will not have to perform exercises related to this information, a psychoeducational intervention. Once the study is finished, these participants will receive an email again in case they are interested in taking part in the eBodyProject prevention program.
Study: NCT04993456

Intervention type: PROCEDURE
Intervention: Caridac surgery
Description: Cardiac surgery
Study: NCT05108025

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical Powder
Description: Topical Powder mixed with diluent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Topical Powder
Description: Placebo Topical Powder mixed with diluent
Study: NCT06605313

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SQ-Kyrin-T Transcatheter Tricuspid Valve Repair System
Description: Transcathether Edge-to-Edge repair for tricuspid regurgitation with SQ-Kyrin-T Transcatheter Tricuspid Valve Repair System.
Study: NCT06604286

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery.
Description: 8 mg IM dexamethasone injection was given to the groups immediately after the operation area was sutured after impacted dental surgery. Dexamethasone injection in group 1 was made into the masseter muscle. injection; The margo anterior of the mandible was palpated and horizontally parallel to the occlusal level of the mandibular second molar tooth and 1 cm behind the margo anterior towards the mandibular ramus. Bone contact was not taken during the injection and the injection was made by taking negative aspiration.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery.
Description: 8 mg IM dexamethasone injection was given to the group immediately after the operation area was sutured after impacted dental surgery. Dexamethasone injection given to Group 2 was directed to the region between the margo anterior of the mandible and the raphe pterygomandibularis, 1 cm above the occlusal level of the mandibular 2nd molar tooth, and the direction of the syringe from the incisal top of the opposing mandibular canine tooth to this region, and then entering the pterygomandibular cavity.
Study: NCT06603064

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active continuous theta burst stimulation
Description: This intervention involves an active form of continuous theta burst stimulation (cTBS) that will be targeted to the dorsal anterior cingulate cortex based on neural navigation software. cTBS will be delivered in one session, lasting a few minutes, before participants complete additional testing.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active continuous theta burst stimulation
Description: This intervention involves an active form of continuous theta burst stimulation (cTBS) that will be targeted to the dorsal anterior cingulate cortex based on neural navigation software. cTBS will be delivered in one session, lasting a few minutes, before participants complete additional testing.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham continuous theta burst stimulation
Description: This intervention involves an sham form of continuous theta burst stimulation (cTBS) that will be targeted to the dorsal anterior cingulate cortex based on neural navigation software. cTBS will be delivered in one session, lasting a few minutes, before participants complete additional testing.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham continuous theta burst stimulation
Description: This intervention involves an sham form of continuous theta burst stimulation (cTBS) that will be targeted to the dorsal anterior cingulate cortex based on neural navigation software. cTBS will be delivered in one session, lasting a few minutes, before participants complete additional testing.
Study: NCT06605937

Intervention type: OTHER
Intervention: Eustachian milking maneuver with routine postoperative treatment protocol
Description: Eustachian milking maneuver will be applied by the patients parents 3 times a day for 7 days in the post-operative period.

Intervention type: OTHER
Intervention: Routine postoperative treatment protocol
Description: The children adenoidectomy and/or adenotonsillectomy whose parents will not apply eustachian healing maneuvers in the post-operative period.

Intervention type: OTHER
Intervention: Routine postoperative treatment protocol
Description: The children adenoidectomy and/or adenotonsillectomy whose parents will not apply eustachian healing maneuvers in the post-operative period.
Study: NCT06606431

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multileveled-community approach
Description: One-to-one delivered interaction at relational level (Interpersonal Relations, Volunteers) Socio-health interaction at personalized level (Social Work) Group delivered interaction for volunteers (Group Dynamics) Community-level interactions (Social Cohesion, Community Networks)
Study: NCT06606496

Intervention type: DEVICE
Intervention: Bispectral index (BIS)
Description: The bispectral index (BIS) monitor is a quantitative electroencephalographic (EEG) device that is widely used to assess the hypnotic component of anaesthesia, especially when neuromuscular blocking drugs are used. If necessary, it may be necessary to increase or decrease MAC (minimum alveolar concentration) in the testosterone group according to the BIS monitoring value.
Study: NCT06606691

Intervention type: DEVICE
Intervention: Xiaomi Mi Smart Band 8
Description: The wearable device, Xiaomi Mi Smart Band 8, will be used solely for observational purposes to assess its accuracy in measuring sleep parameters, oxygen saturation, and heart rate in comparison to nocturnal polygraphy. Participants are receiving routine care as prescribed by their clinicians, and the wearable device is not part of their medical treatment but is being observed alongside standard polygraphy tests.
Study: NCT06606457

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pain Acknowledgment Coping and Empowerment in CF (PACE CF)
Description: The Pain Acknowledgment Coping and Empowerment in CF (PACE CF) program is a newly developed 3-session mind-body pain management intervention for adults with cystic fibrosis (CF), developed with CF community input. The sessions are delivered by the the CF care team psychologist. Each session will teach mind-body strategies to increase comfort and reduce the impact of pain on the participant\&#39;s life. These strategies include understanding pain in CF from a mind-body perspective, learning relaxation and mindfulness-based skills, identifying and practicing individualized cognitive and behavioral strategies that improve comfort and well-being, and discussing communication skills that empower people living with CF and pain. Participants will receive a workbook that will provide related education and resources and reinforce skill practice.
Study: NCT04787744

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PET-directed Local Therapy using Surgery
Description: Surgery will be used to treat metastases.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: PET-directed Local Therapy using Radiation
Description: Radiation therapy will be used to treat metastases.~Radiation options include:~1. Stereotactic body radiotherapy (SBRT) using 1-10 fractions~2. Conventionally fractionated radiotherapy using elective nodal radiotherapy and a simultaneous integrated boost to involved nodes~The selection of the form of metastasis-directed radiotherapy for each metastasis will be determined using shared decision-making between the treating physician and the Veteran.
Study: NCT03593317

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spironolactone
Description: The doses used in the study are the doses used in standard clinical practice. Initial dose is 25 mg/day until study end . The duration of treatment for each patient is 12 months.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be taken once a day at the same time of day. The duration of treatment for each patient is 12 months.
Study: NCT06638645

Intervention type: PROCEDURE
Intervention: VATS/RATS anatomical lung resection
Description: Perioperative care according to the ERAS protocol for lung surgery
Study: NCT05554341

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nilotinib Hydrochloride Monohydrate
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given IV
Study: NCT04243798

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active TBS-DLPFC
Description: Participants in the active stimulation group will receive intermittent TBS to left DLPFC. The L-DLPFC will be targeted utilizing the Localite neuronavigation system. Stimulation intensity will be standardized at 90% of RMT and adjusted to the skull to cortical surface distance (see Nahas 2004).~Stimulation will be delivered to the L-DLPFC using a MagPro x100 TMS system (MagVenture, Denmark).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham TBS-DLPFC
Description: The parameters in the sham arm will be as above with the internal randomization of the device internally switching to sham in a blinded fashion.
Study: NCT03876262

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxidectin
Description: 2mg tablets, encapsulated for blinding

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxidectin
Description: 2mg tablets, encapsulated for blinding

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ivermectin
Description: 3mg tablets, encapsulated for blinding

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin
Description: 3mg tablets, encapsulated for blinding
Study: NCT05205161

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.
Study: NCT05615389

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Medicinal Cannabis - C12T12
Description: Participants randomised to receive C12T12 Ruby Balanced Oil will commence with 0.008ml/kg/day (0.1 mg/kg/day THC) in two divided doses, and titrate up in four steps (increase by 0.008ml/kg/day every four days) over 16 days up to a maintenance dose of 0.04ml/kg/day (0.5mg/kg/day THC) in two divided doses, with a ceiling dose of 2ml/day (25mg/day THC) for participants weighing 50kg or more. The maintenance dose will then be continued from day 17 until day 42.~Down-titration will occur for 16 days after the end of study visit, in the reverse of the up-titration period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Medicinal Cannabis - C20T5
Description: Participants randomised to the C20T5 Ruby CBD Oil will receive a matched volume to the C12T12 arm during the up-titration, maintenance, and down-titration phases.
Study: NCT05205161

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0466
Description: All patients will receive treatment with the investigational product AZD0466 via intravenous infusion.
Study: NCT06516614

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Coach
Description: Sleep-promoting intervention consisting of 4 phone sessions to improve sleep duration and consistency.
Study: NCT06023420

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 4 Herbs Formula
Description: 4 herbs formula dose: 5g/day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4 Herbs Formula
Description: 4 herbs formula dose: 5g/day
Study: NCT06516614

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diabetes Education
Description: Participants will receive a a binder with educational information about diabetes and educational messages from the study team.
Study: NCT06608823

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcatheter Aortic Valve Replacement (TAVR) using Trilogy THV System
Description: Transcatheter Aortic Valve Replacement (TAVR) with Trilogy Device

Intervention type: DEVICE
Group type: OTHER
Intervention: SAVR
Description: SAVR using commercially available surgical prosthetic valves.
Study: NCT06332209

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Trauma Focused Cognitive Behavioral Therapy
Description: Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT; Cohen et al., 2017) is an evidence-based, manualized treatment protocol designed to treat posttraumatic stress and co-occurring symptoms such as depression and anxiety in trauma-exposed children and youth and their supportive and non-offending caregivers. TF-CBT is divided into nine cognitive and behavioral components, all of which incorporate gradual exposure to trauma memories and reminders

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Trauma Focused Cognitive Behavioral Therapy
Description: Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT; Cohen et al., 2017) is an evidence-based, manualized treatment protocol designed to treat posttraumatic stress and co-occurring symptoms such as depression and anxiety in trauma-exposed children and youth and their supportive and non-offending caregivers. TF-CBT is divided into nine cognitive and behavioral components, all of which incorporate gradual exposure to trauma memories and reminders
Study: NCT06608004

Intervention type: OTHER
Intervention: test taking
Description: Measurement of VAS for sensation of hunger, LFQP-France test, 24-hour semi-quantitative dietary recall, Assessment of energy expenditure linked to physical activity using the IPAQ (International Physical Activity Questionnaire) (only at inclusion), Screening for undernutrition risk factors using the SSQ (Social Support Questionnaire) (only at inclusion), Measurement of body composition by impedancemetry, Measurement of isometric grip strength by handgrip test, Measurement of quality of life (SF36), Study of olfacto-gustatory sensoriality (olfaction via the Sniffin\&#39; Sticks test, gustation via lingual application of impregnated strips and AHSP self-questionnaire) (carried out every other visit) and Measurement of gustatory evoked potentials in response to sugar.
Study: NCT06607068

Intervention type: OTHER
Intervention: None (Observational study)
Description: None (Observational study)

Intervention type: OTHER
Intervention: None (Observational study)
Description: None (Observational study)

Intervention type: OTHER
Intervention: None (Observational study)
Description: None (Observational study)

Intervention type: OTHER
Intervention: None (Observational study)
Description: None (Observational study)