TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05877417

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Creatine Monohydrate
Description: Creatine supplementation for 8 weeks, 5g daily. A 5 day loading phase will be implemented with 20g daily for 5 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Creatine Monohydrate
Description: Creatine supplementation for 8 weeks, 5g daily. A 5 day loading phase will be implemented with 20g daily for 5 days.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blood Flow Restriction
Description: Blood Flow Restriction Cuffs applied during exercise

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Blood Flow Restriction
Description: Blood Flow Restriction Cuffs applied during exercise

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Exercise
Description: Participants will exercise
Study: NCT04909749

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Oneome RightMEd Pharmacogenomic testing Kit
Description: The RightMed test is an end-to-end solution which includes sample collection, pharmacogenomic (PGx) testing services, data analysis, and clinical interpretation that helps physicians select treatments based on evidence-driven predictions of patient drug response and tolerance. Genetic components of an individual's drug response are well established and often included on Food and Drug Administration (FDA) medication labels. The OneOme RightMed test has incorporated existing evidence to classify the risk and likelihood of an antidepressant working for different patients. Patient results for each medication can fall into one of three categories: 1.) Green - use as directed; 2.) Yellow - use with caution; and 3.) Red - adjust dose or choose alternative mediation and can be used proactively or reactively
Study: NCT05230979

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Common bean baked snack (for glycemic index determination)
Description: Participants with normal weight or overweight (n=10) will attend the institute after 10-14 h fasting. At first, two baseline finger-prick blood samples will be collected with 5 min between the samples. Then, they are going to consume 54 g of common bean baked snack with 250 mL of water within 12-15 min. Later, finger-prick blood samples will be taken at 15, 30, 45, 60, 90 and 120 min after starting to eat the test food. Areas under the glucose response curves (iAUC) will be calculated using the trapezoidal rule, ignoring the areas below the fasting value.
Study: NCT06014619

Intervention type: PROCEDURE
Intervention: Mohs surgery
Description: Treatment of a skin disease by Mohs micrographic surgery technique (frozen sections).

Intervention type: PROCEDURE
Intervention: Slow Mohs surgery
Description: Treatment of a skin disease by Slow Mohs technique (formalin fixation and paraffin-embedded sections).
Study: NCT05122572

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Oncolytic Virus Injection (RT-01）
Description: Intravenous injection of RT-01 with or without Nivolumab
Study: NCT05561348

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous auricular vagus nerve stimulation
Description: Transcutaneous auricular vagus nerve stimulation was conducted by transcutaneous electrical stimulation therapy instrument to the cymba conchae of left ear in the vicinity of the auricular branch vagus nerve. Stimulation parameters: frequency = 20 Hz; pulse width = 500 μs, twice a day, 30 minutes each time. In the sham stimulation group, the electrodes were fixed at the same position without releasing current.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous auricular vagus nerve stimulation
Description: Transcutaneous auricular vagus nerve stimulation was conducted by transcutaneous electrical stimulation therapy instrument to the cymba conchae of left ear in the vicinity of the auricular branch vagus nerve. Stimulation parameters: frequency = 20 Hz; pulse width = 500 μs, twice a day, 30 minutes each time. In the sham stimulation group, the electrodes were fixed at the same position without releasing current.
Study: NCT06048757

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Diactive-1 application
Description: Participants will engage in 24 weeks resistance exercise program with goal of maintaining at least 3 sessions per week with 4-5 exercises per session (13-33 minutes). The training intervention will comprise 3-4 sets of 6-12 repetitions and will consist of a combination of exercises for the upper and lower body and the core, utilizing the participants' body weight as the primary resistance or auxiliary materials such as elastic bands and a water-fillable kettlebell. The load and intensity of the exercise will be based on the number of repetitions, the resistance of the elastic bands and/or the weight of the aquaball, as well as the difficulty of the exercises. A mobile application known as Diactive-1 will be utilized.
Study: NCT06588725

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Play Nicely
Description: Multimedia tool and handbook designed to educate parents about healthy discipline strategies.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Play Nicely
Description: Multimedia tool and handbook designed to educate parents about healthy discipline strategies.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cavity Prevention Handout
Description: Two page handout with information about how to prevent cavities.
Study: NCT05125393

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic linear stapler
Description: The ileocecal or ascending colon tumors were resected using a combined cephalic caudal approach. When the accessory right colonic vein is separated from the head and then turned to the caudal side for upward dissociation. After no metastasis of 203 groups of lymph nodes is confirmed according to ICG development during the operation, the Henle stem and its root tissue were resected with a linear stapler.
Study: NCT06489054

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peer education
Description: An initial assessment will be carried out to determine the socioeconomic, demographic profile and dental data and baseline data on literacy and attitudes related to oral health through questionnaires, after which participants will be invited to participate in a cycle of oral health education activities for three months on the experimental group (peer-based education). After the experimental stage, the literacy and attitudes questionnaires related to oral health will be reapplied, so that a comparative analysis can be carried out within and between groups.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional education
Description: An initial assessment will be carried out to determine the socioeconomic, demographic profile and dental data and baseline data on literacy and attitudes related to oral health through questionnaires, after which participants will be invited to participate in a cycle of oral health education activities for three months on the control group (dentist lecture). After the experimental stage, the literacy and attitudes questionnaires related to oral health will be reapplied, so that a comparative analysis can be carried out within and between groups.
Study: NCT04913350

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Russian current
Description: One of the preferred common neuromuscular electrical stimulation techniques for muscle strengthening is the Russian current (RC) It stimulates almost all muscle motor units to contract synchronously, resulting in a greater muscle hypertrophy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: elbow support
Description: tennis elbow brace is recommended to decrease pain and improve function by restricting the movement of the forearm or relieving loads on the origin of the muscles of the extensor

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: elbow support
Description: tennis elbow brace is recommended to decrease pain and improve function by restricting the movement of the forearm or relieving loads on the origin of the muscles of the extensor
Study: NCT05348408

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: platelet rich plasma
Description: perineural PRP injection under ultrasound guidance in addition to medical treatment

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: platelet rich plasma
Description: perineural PRP injection under ultrasound guidance in addition to medical treatment
Study: NCT05611905

Intervention type: COMBINATION_PRODUCT
Intervention: 11C-para-aminobenzoic acid PET/CT
Description: A bolus of 20 mCi of 11C-PABA followed by PET/CT

Intervention type: DRUG
Intervention: Probenecid
Description: Oral dose of 500 mg (tablet) 2 hours before IV dose of 11C-PABA will be administered.
Study: NCT00721656

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KLS-0611
Study: NCT05766072

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: EMOTION Kids coping with anxiety and depression (Kendall et. al, 2013) (Mestrende barn in Norwegian) Martinsen et al, 2014
Description: The intervention is transdiagnostic and based on cognitive behavioral therapy where the children and their parents meet i groups led of school health nurses. They are learning coping skills to meet challenging and avoided situations, learning about emotion regulation, physical symptoms conitive restructuring and exposure/behavioral activation. Te manual is publshed in a US/English version and in a Norwegian version.
Study: NCT05089058

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief, digitally delivered imagery-competing task intervention package, comprised of:
Description: Two sessions guided (remotely) by a researcher. Sessions comprised of:~(i) task procedure: a memory cue followed by playing imagery-competing computer game task with mental rotation instructions. Monitoring of intrusive memories to select hotspot cue, and which intrusion to target.~(ii) accompanying information, including rationale for the brief cognitive task.~(iii) option to use the brief cognitive task after the session (self-administered); option to engage in up to 6 guided booster sessions supported by a researcher.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Brief, digitally delivered relaxation task intervention, comprised of:
Description: Brief, digitally delivered relaxation task intervention, comprised of:~Two sessions guided (remotely) by a researcher. Sessions comprised of:~(i) relaxation exercise task using instruction components from progressive muscle relaxation~(ii) accompanying information, including rationale for the brief relaxation exercise task.~(iii) option to use the brief relaxation exercise task after the session (self-administered); option to engage in up to 6 guided booster sessions supported by a researcher.
Study: NCT04573413

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inhibitory repetitive transcranial magnetic stimulation
Description: r-TMS Parameters: International 10/20 system for the location of the target area (left parietal cortex) 60% Power Frequency: 1 Hz 90 pulse trains with 10 pulses each (total 900 stimuli), resulted in a total stimulation period of 15 minutes.~Visual Scanning Visual-spatial training; Reading and copying training; Copying of line drawings on a dot matrix. Barrage

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Group
Description: Sham stimulation and Visual scanning training Intervention: Device: SHAM
Study: NCT04950556

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Pelvic floor muscle exercise will be given to the exercise group

Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: No intervention
Study: NCT05391022

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pelabresib
Description: Pelabresib monohydrate tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pelabresib
Description: Pelabresib monohydrate tablets
Study: NCT04329858

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: silver modified glass ionomer
Description: occlusal cavity filled with silver modified

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: zinc modified
Description: occlusal cavity filled with zinc modified

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional glass ionomer
Description: occlusal cavity filled with conventional glass ionomer
Study: NCT05139641

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Counseling to preserve fertility
Description: Counseling to preserve fertility VS Control group

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counseling to preserve fertility
Description: Counseling to preserve fertility VS Control group
Study: NCT05080673

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Description: The five- and ten-year colonoscopies, in addition to any unscheduled colonoscopies, will be performed according to currently accepted guidelines for the performance of quality colonoscopy. Participants will be given the standardized colonoscopy preparation instructions per institutional standards.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Description: The five- and ten-year colonoscopies, in addition to any unscheduled colonoscopies, will be performed according to currently accepted guidelines for the performance of quality colonoscopy. Participants will be given the standardized colonoscopy preparation instructions per institutional standards.
Study: NCT06061874

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: FAPI PET/CT
Description: The radiopharmaceutical 68Gallium-FAPI-46 (FAPI) is applied intravenously for molecular imaging of FAP expression with FAPI PET/CT.
Study: NCT05264649

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: acupuncture
Description: The acupuncture group were consisted of twelve 30 minutes sessions 2 times per week sessions for 6 weeks. The acupoints were included full body protocol (LI4, LR3, and PC7) and joint-specific protocol tailored as many as three of the patient's most painful joint areas. After 20 minutes De Qi reported by patients, needles were restimulated manually and removed after an additional 10 minutes.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: acupuncture
Description: The acupuncture group were consisted of twelve 30 minutes sessions 2 times per week sessions for 6 weeks. The acupoints were included full body protocol (LI4, LR3, and PC7) and joint-specific protocol tailored as many as three of the patient's most painful joint areas. After 20 minutes De Qi reported by patients, needles were restimulated manually and removed after an additional 10 minutes.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Guizhi-Shaoyao-Zhimu decoction
Description: The patients consumed GZSD (4g paper bagged medicine) three times per day (total daily dose was 12 g/day) continuously during the 6-week intervention period.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Guizhi-Shaoyao-Zhimu decoction
Description: The patients consumed GZSD (4g paper bagged medicine) three times per day (total daily dose was 12 g/day) continuously during the 6-week intervention period.
Study: NCT05342922

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound group
Description: In the operating room, all of the patients will receive standard monitoring. Scans will be made in logiditunal parasagittal and transverse midline views with ultrasound. Needle entry sites in the L2-L3 and L3-L4 intervals will be determined as the intersection of the longiditunal and transverse lines.~When the spinal puncture operator is outside the room, Needle entry sites were marked for both groups.After skin marking, the pregnant woman will be asked to remain still and a subarachnoid puncture will be performed immediately. Spinal anesthesia will be administered with injection of intrathecal bupivacaine.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Landmark group
Description: In the Landmark group, the injection site will be determined using the traditional method of palpating the posterior superior iliac spine.When the spinal puncture operator is outside the room, Needle entry sites were marked for both groups.After skin marking, the pregnant woman will be asked to remain still and a subarachnoid puncture will be performed immediately. Spinal anesthesia will be administered with injection of intrathecal bupivacaine.
Study: NCT04892212

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sirolimus
Description: The daily dose of sirolimus is divided twice.
Study: NCT05789784

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mymobility Physical Therapy
Description: Physical therapy protocol administered at home through the mymobility application.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Office-based Physical Therapy
Description: Physical Therapy protocol administered through exercise handouts and formal office-based therapy directed by physical therapist.
Study: NCT06002139

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Immersive Virtual Reality Therapy
Description: 8 sessions of VR therapy over 4 weeks (each of them 20 minutes long).~As a virtual reality source, VRTierOne device (Stolgraf®) were used. Thanks to using head mounted display and the phenomenon of total immersion VR therapy provides an intense visual, auditory and kinesthetic stimulation. It can have a calming and mood-improving effect or help the patients recognize their psychological resources and motivate to the rehabilitation process. In the virtual therapeutic garden there are a rich set of symbols and metaphors based on Ericksonian Psychotherapy approach. The most important is the Garden of Revival which symbolizes the patient's health. It used to be full of life and energy, now it is neglected, requires work to be revived. In the therapeutic process day by day, the therapist tells the patient a symbolic story about his/her situation.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional rehabilitation
Description: Four weeks of conventional rehabilitation including:~* Two hours of kinesiotherapy (120 minutes, including gait training).~* Thirty minutes of ergotherapy.~* Three physical therapy procedures (i.e. laser therapy, magnetic therapy, electrotherapy) tailored to individual ailments and needs.
Study: NCT05745480

Intervention type: OTHER
Intervention: Opioid Misuse Screening with an Addiction Consult Service
Description: Opioid Misuse Screening with an addiction consult service for brief intervention/motivational interviewing (MI), medication assisted treatment (MAT), or referral to substance use treatment as an outpatient.
Study: NCT06002139

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conventional rehabilitation
Description: Four weeks of conventional rehabilitation including:~* Two hours of kinesiotherapy (120 minutes, including gait training).~* Thirty minutes of ergotherapy.~* Three physical therapy procedures (i.e. laser therapy, magnetic therapy, electrotherapy) tailored to individual ailments and needs.
Study: NCT05032274

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based Exercise Program
Description: The exercise program will include chink tuck and shoulder retraction exercises. The chin tuck exercise will be performed in standing position. The shoulder retraction exercise includes activation and strengthening components. The activation component will be performed in standing position and strengthening component will be performed in prone position.
Study: NCT05274581

Intervention type: OTHER
Intervention: A new type of ultrasound course
Description: All participants will receive the educational intervention. The educations intervention consists of three teaching seminars over three months, a curriculum of 10 point-of-care ultrasound applications, an online learning platform providing educational support before, during and after the teaching sessions.
Study: NCT06284395

Intervention type: DRUG
Intervention: Bortezomib
Description: Bortezomib 1.3mg/m2 SC on days 1,4, 8,11 to the TD scheme for a total of 6 treatment cycles (14,15) (VTD)

Intervention type: DRUG
Intervention: Bortezomib
Description: Bortezomib 1.3mg/m2 SC on days 1,4, 8,11 to the TD scheme for a total of 6 treatment cycles (14,15) (VTD)
Study: NCT06523907

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention Basic Nursing skills
Description: Evaluating the effectiveness of the education program in improving paramedics' knowledge of essential nursing care principles, such as hygiene practice, infection control, safe administration of injection, blood draw, vital sign monitoring, respiratory rate

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Present Knowledge about basic nursing skill
Description: Assess the current and baseline knowledge status of the participants about the hygiene practice, infection control, safe administration of injection, blood draw, vital sign monitoring, respiratory rate
Study: NCT04611867

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supportive application with integrated weekly PRO
Description: Patients will fill in a web-based application PRO-CTCAE with integrated preparation questionnaire every week. If their weekly reported symptoms exceed a predefined threshold of severity, this results in a notification on the staff application interface and a nurse will contact a patient for verification of symptoms. Nurse will review patient recent treatment and PRO reports and advise patient according to the local practice for symptom management and reinforce reporting. Nurse will consult with or refers to (if possible) treating physician if patient will require medical intervention and/or physician assistance.
Study: NCT06636084

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Guided bone regeneration (GBR)
Description: A composite graft composed of a 50:50 proportion of autogenous bone and a demineralized bone mineral will be positioned around the bony defect or placed in the membrane, depending on the group randomization. The selected membrane will then be secured with screws to ensure a complete and stable coverage of the grafted area.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Guided bone regeneration (GBR)
Description: A composite graft composed of a 50:50 proportion of autogenous bone and a demineralized bone mineral will be positioned around the bony defect or placed in the membrane, depending on the group randomization. The selected membrane will then be secured with screws to ensure a complete and stable coverage of the grafted area.
Study: NCT06630078

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Wevosys acoustic analysis
Description: Recording of voice signal of subjects enrolled