TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04768322

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HeartMate 3 TM Left Ventricular Assist System
Description: The HeartMate 3 TM Left Ventricular Assist System will be implanted within 21 days of randomization.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Guideline Directed Medical Therapy
Description: Patients randomized in the control group will continue their guideline directed medical therapy which comprises the following stable combination at the maximal tolerated dose of betablockers, Angiotensin-Converting-Enzyme-inhibitors or Angiotensin II Receptor Blockers or Angiotensin receptor Neprilysin inhibitor and Mineralocorticoid Receptor Antagonists and Sodium-GLucose co-Transporter-2 (SGLT2) inhibitors if tolerated.

Intervention type: OTHER
Group type: OTHER
Intervention: Guideline Directed Medical Therapy
Description: Patients randomized in the control group will continue their guideline directed medical therapy which comprises the following stable combination at the maximal tolerated dose of betablockers, Angiotensin-Converting-Enzyme-inhibitors or Angiotensin II Receptor Blockers or Angiotensin receptor Neprilysin inhibitor and Mineralocorticoid Receptor Antagonists and Sodium-GLucose co-Transporter-2 (SGLT2) inhibitors if tolerated.
Study: NCT05746351

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: a group will receive epidural Bupivacaine with Dexmedetomidine in normal labor

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: fentanyl
Description: a group will receive epidural Bupivacaine with fentanyl in normal labor

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nalbuphine
Description: a group will receive epidural Bupivacaine with Nalbuphine in normal labor
Study: NCT06011005

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ethyl Chloride spray (group A)
Description: Cold test spray

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Benzocaine gel 20% (group B)
Description: Topical analgesia
Study: NCT05559359

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lebrikizumab
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lebrikizumab
Description: Administered SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo given SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical Corticosteroid (TCS)
Description: TCS administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical Corticosteroid (TCS)
Description: TCS administered

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Topical Corticosteroid (TCS)
Description: TCS administered
Study: NCT05149937

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: interprofessional, person-centered care concept
Description: interprofessional, person-centered care concept
Study: NCT06186310

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aquatic Therapy Group
Description: After the initial evaluations, patients will be given aquatic exercises including personalized strengthening, balance and breathing exercises accompanied by a physiotherapist 3 days a week for total 5 weeks. At the same time, the exercises taught as a home program will be asked to be repeated every day for 5 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy Group
Description: After the initial evaluations, patients in the control group will be taught passive, active, actively assisted or resistant upper and lower extremity exercises as a home program, appropriate to each patient's functional level and muscle strength. Subjects will be asked to perform the exercises every day for 5 weeks, not exceeding an average of 45 minutes, 5 to 10 repetitions of each exercise, depending on fatigue.
Study: NCT06068608

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNM005
Description: single,intramuscular injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNM005
Description: single,intramuscular injection
Study: NCT06048042

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autogenous Demineralized Dentin Graft
Description: The participant's own freshly extracted tooth will be cleaned from periodontal ligaments, cementum, soft tissue attachment, caries, or restorations (if present) and have their crown decapitated, using a high- speed fine finishing stone and saline irrigation. The pulp chamber and root pulp will be cleaned by split opening the root and cleaning it out using a high-speed diamond bur. Subsequently, teeth will be ground, and demineralized using a hand bone mill. Then the particles will be prepared by demineralization of tooth particles in 0.6N hydrochloric acid5 for 30 min then washed twice in saline and dried with sterile gauze. Then it will be used as a graft for the intra-bony defect after modified minimally invasive surgical technique.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Autogenous Bone Graft
Description: Modified minimally invasive surgical technique (M-MIST) will be performed in the intra-bony defects, with autogenous bone graft placement. The graft will be harvested from the retromolar area using automatic chip maker (ACM) bur and a hand bone mill will be used to grind the chips into particles, then it will be placed in the defect.
Study: NCT05920252

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vira
Description: Intensive outpatient DBT supported by the Vira platform. The Vira app is installed on the patient's smartphone. The app passively collects data from phone sensors (i.e., measures of physical activity, sleep patterns, mobility, and language patterns reflecting mood states and cognition) that are indicative of risk-relevant behavioral patterns and psychological states. It also prompts users to answer a daily check in question. Mobile sensing data are processed to provide an automated assessment of the user's functioning. Patients will be asked to use Vira for the duration of their intensive outpatient treatment. Patients' use of the Vira app is supported by practitioners, who can schedule just-in-time reminders (i.e., nudges) to arrive in the user's phone at scheduled times to support their behavior change plan and DBT treatment. The Vira Platform therefore integrates mobile sensing, self-report assessment, and just-in-time nudges and notifications into the practitioner's workflow.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual (TAU)
Description: Intensive outpatient DBT + EARS app (passive data monitoring software)
Study: NCT06368609

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: IgG RDT
Description: Sera will be thawed at room temperature; 15 µL of serum will be added to the sample pad of each dipstick, which will then be placed upright into a well containing 3 drops of buffer. The pads at the bottom of the dipstick shall then wick up the buffer to run up the nitrocellulose membrane towards the absorbent pad. The results can be read after 15-20 minutes. The presence of the control line will indicate proper execution of the test, with valid result. In case of absence of this line, the result will be considered invalid. Positive results will be defined as test with presence of both control and positive (including faint) lines; negative results will be defined as tests with presence of control line only.
Study: NCT05011383

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose testosterone
Description: High dose testosterone is administered subcutaneously once monthly until progression or toxicity

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose testosterone
Description: High dose testosterone is administered subcutaneously once monthly until progression or toxicity

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose testosterone
Description: High dose testosterone is administered subcutaneously once monthly until progression or toxicity
Study: NCT04891198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envafolimab
Description: Subcutaneous injection
Study: NCT06368609

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: IgG4 RDT
Description: Sera will be thawed at room temperature; 15 µL of serum will be added to the sample pad of each dipstick, which will then be placed upright into a well containing 3 drops of buffer. The pads at the bottom of the dipstick shall then wick up the buffer to run up the nitrocellulose membrane towards the absorbent pad. The results can be read after 15-20 minutes. The presence of the control line will indicate proper execution of the test, with valid result. In case of absence of this line, the result will be considered invalid. Positive results will be defined as test with presence of both control and positive (including faint) lines; negative results will be defined as tests with presence of control line only.
Study: NCT05918354

Intervention type: DEVICE
Intervention: Skin Prick Automated Test
Description: Detection of sensitisation to specific allergens via the skin prick automated test.
Study: NCT06637566

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Brandt Daroff exercises along with Cawthorne Cooksey exercises
Description: Brandt Daroff exercises along with Cawthorne Cooksey exercises. The Cawthorne Cooksey exercises include eye and head movements, coordination of eye and head movements (visual-vestibular interaction), postural control exercises, and progressively more difficult balance tasks (eyes open, eyes closed, large base support, uneven base support, while walking, in high visual or noisy environments). Exercises should be done three times a day, with 5 repetitions of each. The exercises will be performed in three sessions per week with 60 minutes each session for eight weeks. The cawthorne Cooksey exercises includes the following:~A: Eye and head movement~B: Head and body movement, sitting down:~C: Standing up exercises:

Intervention type: OTHER
Group type: OTHER
Intervention: Brandt Daroff exercises
Description: brandt daroff exercises without cawthorne Cooksey exercises. To begin the Brandt-daroff exercise, the patient will sit and swivel the head 45 degrees to one side (left), then instantly lie down on the other shoulder (right). The patient should be instructed to maintain this posture for 30 seconds or until the vertigo subsides. The patient then gradually returns to the starting position, maintaining the left ear rotation until sat upright. Following the same 30 second time limits, the patient turns his head in the opposite way (right) and rests down on the opposite shoulder (left). These exercises will be instructed to perform at home for 3 sets (morning, afternoon and evening) with 5 repetitions approximately for 30 minutes in each session for five weeks
Study: NCT05328648

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community Score Card
Description: In Community Score Card intervention, all communities associated with the targeted facilities will assess the primary barriers to quality family planning service delivery and develop indicators. The communities will then each complete the score card and generate ideas for quality improvement. Family planning providers in the target facilities will meet and determine the barriers to high quality family planning service delivery. Providers will decide on priority areas and make suggestions for improving service delivery. Study facilitators will bring these two groups together to share their respective score cards and jointly develop an action. Within the action plan, agreed upon responsibilities will be assigned and a timeline will be communicated.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Citizen Report Card
Description: Citizen Report Card (CRC): The data from the CRC questionnaire will be analyzed and translated into a report card. Extensive dissemination activities will ensure the CRC is widely shared with members of the community. The goal is to create a public record of service quality.
Study: NCT05371327

Intervention type: BEHAVIORAL
Intervention: Public deliberation
Description: Public deliberation is a method for engaging the public in collective decision-making. Its goal is to facilitate debate and discussion that: 1) fosters the formation of reasonable and informed opinions, 2) permits participants to revise their perspectives and positions in light of new information and dialogue with others, and 3) encourages participants to consider not only their own preferences but also the greater goal of a policy or resolution that is justifiable for all persons affected by the issue under debate.
Study: NCT06355297

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education about pelvic floor
Description: The three educational sessions will last 60 minutes, as follows: session1, anatomy of pelvic floor; session2, function and dysfunction of pelvic floor; session3, risk factor for pelvic floor dysfunctions.
Study: NCT05974787

Intervention type: BEHAVIORAL
Intervention: Emergency department cancer patients interview
Description: The interview focuses on several parts of the (pre-)admission process: The first part is regarding the barriers and facilitators encountered during the (pre-)admission process. The second part will focus on the timeline that led to an emergency department (ED) visit. It will be established when and which symptoms were first detected. The third part is regarding the number and type of health care workers that were contacted before visiting the ED. The fourth part will be about the actions and considerations taken before the ED visit.
Study: NCT03662451

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Robotic assisted hysterectomy
Description: Periumbilical single incision vs multiple abdominal incisions for hysterectomy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Robotic assisted hysterectomy
Description: Periumbilical single incision vs multiple abdominal incisions for hysterectomy
Study: NCT05726968

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pilocaine 2% (1.5 ml) and 25 ug fentany
Description: Patients will be randomly allocated into the study groups according to the list of random numbers. The study groups will be as follows:~* Group P1 (N 15): patients assigned to this group will receive intrathecal 30 mg (1.5 ml) of prilocaine 2% (Takipril, prilocaine hydrochloride 20 mg/mL, hyperbar, Sintetica) + 25 ug fentanyl (0.5 ml).~* Group P2 (N 15): patient assigned to this group will receive intrathecal 40 mg (2 ml) of prilocaine 2% + 25 ug fentanyl (0.5 ml).~* Group P3 (N 15): patient assigned to this group will receive intrathecal 50 mg (2.5 ml) of prilocaine 2% + 25 ug fentanyl (0.5 ml).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pilocaine 2% (1.5 ml) and 25 ug fentany
Description: Patients will be randomly allocated into the study groups according to the list of random numbers. The study groups will be as follows:~* Group P1 (N 15): patients assigned to this group will receive intrathecal 30 mg (1.5 ml) of prilocaine 2% (Takipril, prilocaine hydrochloride 20 mg/mL, hyperbar, Sintetica) + 25 ug fentanyl (0.5 ml).~* Group P2 (N 15): patient assigned to this group will receive intrathecal 40 mg (2 ml) of prilocaine 2% + 25 ug fentanyl (0.5 ml).~* Group P3 (N 15): patient assigned to this group will receive intrathecal 50 mg (2.5 ml) of prilocaine 2% + 25 ug fentanyl (0.5 ml).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pilocaine 2% (1.5 ml) and 25 ug fentany
Description: Patients will be randomly allocated into the study groups according to the list of random numbers. The study groups will be as follows:~* Group P1 (N 15): patients assigned to this group will receive intrathecal 30 mg (1.5 ml) of prilocaine 2% (Takipril, prilocaine hydrochloride 20 mg/mL, hyperbar, Sintetica) + 25 ug fentanyl (0.5 ml).~* Group P2 (N 15): patient assigned to this group will receive intrathecal 40 mg (2 ml) of prilocaine 2% + 25 ug fentanyl (0.5 ml).~* Group P3 (N 15): patient assigned to this group will receive intrathecal 50 mg (2.5 ml) of prilocaine 2% + 25 ug fentanyl (0.5 ml).
Study: NCT06344416

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of ReX to dispense and monitor solid oral medication therapy.
Description: ReX Remote Digital Nurse comprising hand-held dispenser, disposable drug cartridge and web application (ReX Treatment Manager).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of ReX to dispense and monitor solid oral medication therapy.
Description: ReX Remote Digital Nurse comprising hand-held dispenser, disposable drug cartridge and web application (ReX Treatment Manager).
Study: NCT06564194

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JCXH-108
Description: IM injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: IM injection
Study: NCT06558578

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Helicobacter pylori antigen in stool
Description: H pylori antigen in stool: for all patients suffering from migraine and control group.~Upper GIT endoscopy: for children with positive H Pylori antigen in stool.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Helicobacter pylori antigen in stool
Description: H pylori antigen in stool: for all patients suffering from migraine and control group.~Upper GIT endoscopy: for children with positive H Pylori antigen in stool.
Study: NCT06436781

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Maolactin
Description: Once daily dose of 2 capsules containing a total of 500mg/day Maolactin

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Once daily dose of 2 capsules of Maltodextrin containing a total of 0mg/day Maolactin
Study: NCT04212923

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Medical Dashboard based self-management intervention
Description: Before the start of the intervention, chronic kidney disease patients and care providers will receive a face-to-face training session on the use of Medical Dashboard. To avoid contamination, Medical Dashboard will only be made accessible for participants in the intervention group via a secure password-protected registration process.
Study: NCT05508126

Intervention type: DIAGNOSTIC_TEST
Intervention: DECT examination
Description: DECT examinations will be performed using a 192-slice CT scanner (SOMATOM, Force, Siemens, Forchheim, Germany).

Intervention type: DIAGNOSTIC_TEST
Intervention: DECT examination
Description: DECT examinations will be performed using a 192-slice CT scanner (SOMATOM, Force, Siemens, Forchheim, Germany).

Intervention type: DIAGNOSTIC_TEST
Intervention: mpMRI examination
Description: The examinations were conducted on a 3-T MR scanner (MAGNETOM Skyra; Siemens Healthcare, Erlangen, Germany).

Intervention type: DIAGNOSTIC_TEST
Intervention: mpMRI examination
Description: The examinations were conducted on a 3-T MR scanner (MAGNETOM Skyra; Siemens Healthcare, Erlangen, Germany).
Study: NCT04621877

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Volunteer-delivered Behavioral Activation
Description: Behavioral Activation as delivered by trained volunteers

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Master's level clinician-delivered Behavioral Activation
Description: Behavioral Activation as delivered by trained master's level clinicians
Study: NCT06421350

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal Cord Stimulation Device
Description: The closed-loop spinal cord stimulation mechanism uses dynamic adjusting stimulation parameters based on real-time physiologic response and is uniquely positioned to mitigate the aberrant inflammatory and neurosensory processing and autonomic dysfunction driving CRPS and its progression between phases.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal Cord Stimulation Device
Description: The closed-loop spinal cord stimulation mechanism uses dynamic adjusting stimulation parameters based on real-time physiologic response and is uniquely positioned to mitigate the aberrant inflammatory and neurosensory processing and autonomic dysfunction driving CRPS and its progression between phases.
Study: NCT06445777

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mental Health Prevention and Promotion
Description: The Inner Lion Programme is made up of 12 interactive workshops which are based on four key pillars: building confidence by identifying strengths and personal qualities; improving emotional intelligence and self-awareness; establishing adaptive coping strategies and channels of support; and boosting resilience. Professionally created by Child Psychologist Stijn de Leeuw together with an advisory team of psychologists from the Netherlands and South Africa, the programme follows a carefully structured and curated prevention and promotion mental health curriculum with games, crafting activities, psycho-educational stories, dance, movement, and breathing exercises. Workshops are led by local role models (a male-female duo) with lived experience trained to be mental health coaches.
Study: NCT05135260

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual reality therapy
Description: Participants will watch a video allowing them to view nature, dinosaurs, animals, and human interactions in three dimensions during a session lasting 11 minutes.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaires
Description: Questionnaires will be completed regarding stress, pain and affect

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: Questionnaires will be completed regarding stress, pain and affect

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Measure heart rate
Description: To be measured prior to starting treatment and halfway through the 11 minute Video

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Measure heart rate
Description: To be measured prior to starting treatment and halfway through the 11 minute Video

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cyber sickness measurement
Description: To be measured using the fast motion sickness scale
Study: NCT04683653

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiation
Description: Radiation treatment in which the total dose of radiation is divided into large doses and treatments are given less often. Hypofractionated radiation therapy is given over a shorter period of time (fewer days or weeks) than standard radiation therapy.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical Follow-Up and Assessments
Description: At each visit, the subject will be evaluated for any signs of their endometrial cancer or symptoms returning (clinical disease recurrence) and any negative side effects associated with their prior radiation treatment. Study participants will also be asked to fill out a survey regarding bowel/urinary habits and quality of life questionnaires (known as the EPIC questionnaire) during these visits. The data collected during these clinical follow up visits will be used to determine how effective hypofractionated/shortened whole radiation therapy is for treating endometrial cancer.