TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05241210

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AI program for colonoscopy
Description: Provides real-time feedback on the endoscopist moniter during colonoscopy.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AI program for colonoscopy
Description: Provides real-time feedback on the endoscopist moniter during colonoscopy.
Study: NCT05961514

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Target biopsies
Description: MRI/Fusion target biopsies combine magnetic resonance imaging (MRI) with ultrasound-guided biopsy techniques to obtain tissue samples from areas of the prostate gland that appear abnormal on MRI.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: systemic biopsies
Description: transrectal ultrasound (TRUS) guided prostate systemic biopsies
Study: NCT05896553

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intranasal Oxytocin(24IU)
Description: Administration of intranasal Oxytocin(24IU)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: intranasal Placebo
Description: Administration of intranasal Placebo
Study: NCT06324097

Intervention type: DIAGNOSTIC_TEST
Intervention: endocytoscopy
Description: The colorectal lesions had been observed with EC-NBI and EC-stained by endoscopists before treatment that were ultimately performed histopathologic examination. The endocytoscopies (CF-H290ECI, Olympus, Tokyo, Japan) have a maximum magnification of ×520, focusing depth, 35 μm; field of view, 570 × 500μm. During EC-NBI , the endoscopist pushed the button of the endoscope to switch from white-light imaging to NBI and observed the lesion with full magnification. Finally, the endoscopist performed EC-stained mode diagnosis after staining the lesion surface with 1.0% methylene blue.
Study: NCT05823714

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEN+AZA+Modified BUCY
Description: Venetoclax: 200mg/day\*7days（It should be combined with triazole antifungal drugs).~Azacytidine: 75mg/ m²/day\*7days.
Study: NCT06157684

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Postprandial ambulation
Description: See arm description
Study: NCT05872243

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active rTMS
Description: Each participant will receive two 1800 pulse active rTMS in each session, with a 50-minute break in between. Participants will receive two separate sessions daily (a sum of 7200 pulses per day). The intervention will take place for 15 continuous days.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active rTMS
Description: Each participant will receive two 1800 pulse active rTMS in each session, with a 50-minute break in between. Participants will receive two separate sessions daily (a sum of 7200 pulses per day). The intervention will take place for 15 continuous days.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham rTMS
Description: Each participant will receive two 1800 pulse sham rTMS in each session, with a 50-minute break in between. Participants will receive two separate sessions daily (a sum of 7200 pulses per day). The intervention will take place for 15 continuous days.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham rTMS
Description: Each participant will receive two 1800 pulse sham rTMS in each session, with a 50-minute break in between. Participants will receive two separate sessions daily (a sum of 7200 pulses per day). The intervention will take place for 15 continuous days.
Study: NCT03068247

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Duloxetine
Description: 10 week treatment

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 10 week treatment
Study: NCT06064578

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Project SOLVE
Description: Project SOLVE is a \~30-minute self-guided digital intervention designed to teach children and adolescents how to set goals and solve problems systematically. Specifically, Project SOLVE is based on problem solving, a core component of cognitive behavioral therapy, a gold standard treatment for internalizing disorders. Project SOLVE uses vignettes, interactive activities, and engaging graphics to teach youth a systematic strategy for solving problems. Project SOLVE was previously found to be effective in reducing mental health symptoms among American children (https://link.springer.com/article/10.1007/s12310-023-09598-7).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Project SOLVE
Description: Project SOLVE is a \~30-minute self-guided digital intervention designed to teach children and adolescents how to set goals and solve problems systematically. Specifically, Project SOLVE is based on problem solving, a core component of cognitive behavioral therapy, a gold standard treatment for internalizing disorders. Project SOLVE uses vignettes, interactive activities, and engaging graphics to teach youth a systematic strategy for solving problems. Project SOLVE was previously found to be effective in reducing mental health symptoms among American children (https://link.springer.com/article/10.1007/s12310-023-09598-7).
Study: NCT05987787

Intervention type: PROCEDURE
Intervention: laparoscopic sleeve gastrectomy without suture reinforcement
Description: The procedure begins by dissecting the small branches of the gastroepiploic arch 6 cm from the pylorus. The dissection continues along the great curvature of the stomach, remaining very close to the gastric wall, up to the short gastric vessels which are also dissected. The stomach is then raised to expose its posterior wall and the adhesions are lysed. His angle is fully mobilized and the left diaphragmatic pillar exposed. The gastric tubule is created on the guide of a 40 F Bugie using mechanical suturing machines with charges of different thickness depending on the thickness of the gastric wall. At this point the bougie is removed and the resected stomach is extracted from the abdomen through the mesogastric access.

Intervention type: PROCEDURE
Intervention: laparoscopic sleeve gastrectomy with suture reinforcement
Description: The procedure begins by dissecting the small branches of the gastroepiploic arch 6 cm from the pylorus. The dissection continues along the great curvature of the stomach, remaining very close to the gastric wall, up to the short gastric vessels which are also dissected. The stomach is then raised to expose its posterior wall and the adhesions are lysed. His angle is fully mobilized and the left diaphragmatic pillar exposed. The gastric tubule is created on the guide of a 40 F Bugie using mechanical suturing machines with charges of different thickness depending on the thickness of the gastric wall. At this point the bougie is removed and the resected stomach is extracted from the abdomen through the mesogastric access. At this point, it is applied running seromuscular stitches at the proximal third of the stapled line using unidirectional 2/0 barbed sutures to invaginate the staple line completely.
Study: NCT04394715

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Alert
Description: Providers will see an automated electronic alert for each eligible hyperlipidemia patient at high risk for future atherosclerotic CVD events. This alert will appear when the provider enters the order entry screen in the patient's medical record during the patient's first eligible outpatient visit. The alert consists of a pop up that notifies the physician that the patient is at very high risk for ASCVD events, displays the most recent cholesterol values and the patient's current lipid lowering therapy. It also includes a link to full treatment guidelines for hyperlipidemia, which includes a continuing medical education (CME) option to obtain CME credits.
Study: NCT05728073

Intervention type: PROCEDURE
Intervention: ERCP
Description: Patients separated to two groups according to having a ERCP history before the operation
Study: NCT05335902

Intervention type: DIAGNOSTIC_TEST
Intervention: ultrasound measurement of the optic nerve sheath diameter
Description: ultrasound measurement of the optic nerve sheath diameter

Intervention type: DIAGNOSTIC_TEST
Intervention: ultrasound measurement of the optic nerve sheath diameter
Description: ultrasound measurement of the optic nerve sheath diameter

Intervention type: DIAGNOSTIC_TEST
Intervention: MoCA test
Description: MoCA test is a short bedside test for measuring cognitive disfunction

Intervention type: DIAGNOSTIC_TEST
Intervention: MoCA test
Description: MoCA test is a short bedside test for measuring cognitive disfunction
Study: NCT05356338

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pilot Intervention to reduce SSB consumption in children and families enrolled in WIC
Description: A 6-month intervention based on the use of 5 components: 2 educational videos, provision of a water-promotion toolkit, a mobile phone application (app), a series of 14 computerized interactive voice response (IVR) phone calls to parents and 2 counseling sessions by a WIC nutritionist to compare families' SSB's consumption behaviors
Study: NCT05337592

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 1
Description: BI 1815368 formulation 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 1
Description: BI 1815368 formulation 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 1
Description: BI 1815368 formulation 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 1
Description: BI 1815368 formulation 1

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 2
Description: BI 1815368 formulation 2

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 2
Description: BI 1815368 formulation 2

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1815368 formulation 2
Description: BI 1815368 formulation 2
Study: NCT06086028

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wrist worn sensor
Description: Biostrap collects biometrics such as the following: (1) sleep pattern/ quality; (2) steps, activity, calories; (3) heart rate/ HRV; (4) respiratory rate. Participants will be randomly assigned to one of two groups.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wrist worn sensor
Description: Biostrap collects biometrics such as the following: (1) sleep pattern/ quality; (2) steps, activity, calories; (3) heart rate/ HRV; (4) respiratory rate. Participants will be randomly assigned to one of two groups.
Study: NCT02500784

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Formoterol A
Description: 20mg/2mL, BID inhaler for 12 months: until progression or unacceptable toxicity develops.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Formoterol B (placebo)
Description: 2mL, BID inhaler for 12 months
Study: NCT06330727

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Coffee capsule
Description: Take 12 coffee capsules containing 3.6 g instant black coffee powder per day (take 6 coffee capsules twice daily with breakfast and lunch).

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Corn starch capsule
Description: Take 12 placebo capsules containing 3.6 g corn starch per day (take 6 placebo capsules twice daily with breakfast and lunch).
Study: NCT04491045

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Workshop Training on Multicomponent Collaborative Care for Depression
Description: Hybrid Workshop Trainings on Stepped collaborative care model for depression that involves using a team-based approach to integrating depression care components (screening, psychoeducation, Behavior Activation therapy, and antidepressant medications) into primary care settings. This integration involves task-shifting mental health tasks from mental health specialist to community providers at the commune health stations.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Workshop Training on Multicomponent Collaborative Care for Depression
Description: Hybrid Workshop Trainings on Stepped collaborative care model for depression that involves using a team-based approach to integrating depression care components (screening, psychoeducation, Behavior Activation therapy, and antidepressant medications) into primary care settings. This integration involves task-shifting mental health tasks from mental health specialist to community providers at the commune health stations.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Workshop Training on Multicomponent Collaborative Care for Depression
Description: Hybrid Workshop Trainings on Stepped collaborative care model for depression that involves using a team-based approach to integrating depression care components (screening, psychoeducation, Behavior Activation therapy, and antidepressant medications) into primary care settings. This integration involves task-shifting mental health tasks from mental health specialist to community providers at the commune health stations.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervision
Description: Ongoing supervision and coaching is provided to community health providers by local mental health specialist from the provincial psychiatric hospital for 6-9 months

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervision
Description: Ongoing supervision and coaching is provided to community health providers by local mental health specialist from the provincial psychiatric hospital for 6-9 months

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Community-Engaged Learning Collaborative
Description: The CELC group will receive support for continuous quality improvement using a province-wide learning collaborative that will meet monthly for 3 months, followed by bi-monthly meetings for 12 months.
Study: NCT05969132

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fully digital guided gingivectomy procedure
Description: 1. Full history with clinical and radiographic examination (CBCT) to aid in patient's selection.~2. Supra- and sub-gingival debridement.~3. Oral hygiene instructions (OHI)~4. Presurgical intraoral scanning using an intraoral scanner (IOS)~5. Fabrication of the Gingivectomy guide:~   * Convert (DICOM) file to STL file then merged to STL file corresponding oral soft tissues 3D data obtained by IOS using software of surgical planning.~  * Digital waxing up with new desired positions of gingival margins and zenith points performed.~  * Designing Gingivectomy guide then exported to a 3D printer and mill a transparent resin gingivectomy guide.~6. Surgical Procedure: anesthetized the patient using local anesthesia, Surgical incision using 15c blade following CEJ anatomy will be made at each tooth using the Gingivectomy guide as reference to new gingival level and being careful to preserve the gingival papillae without involving the palatal surfaces.~7. Postoperative care

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Convectional guided gingivectomy procedure
Description: 1. Full history with clinical and radiographic examination (CBCT) to aid in patient's selection.~2. Supra- and sub-gingival debridement with OHI~3. Gingivectomy guide fabrication:~   * Impressions and casts obtained.~  * Waxing-up included new positions of gingival margins and zenith points.~  * Silicone index with condensation silicone impression materials made with pressure on the cast to reproduce the details of the wax, then filled after setting with resin material and placed in the patient's mouth.~  * Resin mock-up trimmed with blade to define the correct new gingival level.~  * After the patient accept the mock-up design will used as Gingivectomy guide.~4. Surgical Procedure: anesthetized the patient using local anesthesia, Surgical incision using 15c blade following CEJ anatomy will be made at each tooth using the Gingivectomy guide as reference to new gingival level and being careful to preserve the gingival papillae without involving the palatal surfaces.~5. Postoperative care
Study: NCT05240521

Intervention type: OTHER
Group type: OTHER
Intervention: ARM A
Description: 30 IBS-C patients will receive GA-AT0119 for 28 days, followed by a washout period of 28 days and Placebo for another 28 days

Intervention type: OTHER
Group type: OTHER
Intervention: ARM A
Description: 30 IBS-C patients will receive GA-AT0119 for 28 days, followed by a washout period of 28 days and Placebo for another 28 days

Intervention type: OTHER
Group type: OTHER
Intervention: ARM B
Description: 30 IBS-C patients will receive Placebo for 28 days, followed by a washout period of 28 days and GA-AT0119 for another 28 days

Intervention type: OTHER
Group type: OTHER
Intervention: ARM B
Description: 30 IBS-C patients will receive Placebo for 28 days, followed by a washout period of 28 days and GA-AT0119 for another 28 days
Study: NCT06380894

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Cognitive Training
Description: Participants who were assigned to the VRCT intervention group underwent 60 minutes of weekly VRCT sessions over a 10-week intervention period. The program consisted of two components: (1) psychoeducation on cognitive functioning and ways to maintain cognitive health, (2) VR multi-domain cognitive training tasks that target cognitive domains of attention, memory, and executive functioning.~The VR experiences were administered through a head-mounted Oculus Go Screen V7. The VR system runs on a software developed by Dancing Mind Pte Ltd. The software specifications and service provided by Dancing Mind Pte Ltd include: MindGym System Functions: System Setup (Processor Setup, Password Changing etc) and Data Centre (Memory Care Therapy Data Analytics Report Querying and Printing Functions). The MindGym cognitive training content was developed based on the Singaporean culture, with visual stimuli reflecting familiar local environments.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Control
Description: Participants who were assigned to the active control group were provided treatment-as-usual, which included: (1) psychoeducation on MCI, cognitive functioning, and compensatory strategies, and (2) brain training cognitive stimulation booklet which consisted of weekly homework activities focusing on attention, memory, and executive functioning. Control participants were reviewed for 3 sessions monthly to follow up on their progress on the cognitive stimulation activity booklet.
Study: NCT04980365

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: Participants will be asked to use the app Mindfulness Coach daily for 10 minutes. Participants will follow app instructions for brief guided meditation sessions for 14 days.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gratitude
Description: Participants will be asked to use the app Grateful daily for 10 minutes. Participants will follow app instructions and will be answering to prompts related to gratitude provided by the app daily, for 10 minutes for 14 days.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Food Journal
Description: Participants will be asked to use the app Day One daily for 10 minutes. Participants will be writing a daily journal entry describing what they ate during the previous day for 14 days.
Study: NCT04325958

Intervention type: DRUG
Group type: OTHER
Intervention: Cannabis
Description: 750mg cigarette of plant material

Intervention type: DRUG
Group type: OTHER
Intervention: Cannabis
Description: 750mg cigarette of plant material

Intervention type: DRUG
Group type: OTHER
Intervention: Placebos
Description: 750mg cigarette of plant material

Intervention type: DRUG
Group type: OTHER
Intervention: Placebos
Description: 750mg cigarette of plant material
Study: NCT05409144

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thoracic epidural infusion
Description: Upon locating the desired site spot, lidocaine 1% must be injected into the skin and underlying tissues to decrease the discomfort with the advancement of the epidural needle. Once achieving local anesthesia, the epidural needle advanced with its stylet in place and with its bevel point cephalad; this will ultimately contribute to the proper location of the epidural catheter. The epidural needle must be advanced through the skin, subcutaneous tissue, supraspinous, and interspinous ligaments. Once there, the stylet must be removed, and the Loss of Resistance syringe (filled up with saline, air, or both) must be attached to the needle. The needle must be advanced while applying pressure to the plunger. Once the ligamentum flavum is pierced, a loss in resistance will be noted; this is the epidural space, and 5 to 10 cc of saline is injected to expand the epidural space; this may decrease the risk of vascular injury.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Erector Spinae Plane Block
Description: The block-level will be at T5. The ultrasound probe will be placed on the back in a transverse orientation to identify the tip of the T5 transverse process; these are recognizable as flat, squared-off acoustic shadows with only a very faint image of the pleura visible. The tip of the transverse process will be centered on the ultrasound screen and the probe will then be rotated into a longitudinal orientation to produce a parasagittal view, in which the following layers will be visible superficial to the acoustic shadows of the transverse processes: skin and subcutaneous tissue, trapezius, erector spinae muscle and T5 transverse process. 3ml lidocaine 1% will be used on skin and subcutaneous fat, Echogenic block needle will be inserted in-plane to the ultrasound beam in a cranial-to-caudal direction until contact is made with the T5 transverse process.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Serratus Anterior Plane Block
Description: The block is performed with full aseptic precautions. Arm abduction is preferred. The ultrasound probe will be placed on the patient's midaxillary line in the transverse plane, at the level of the fifth rib, with the indicator oriented toward the operator's left. With the rib, pleural line, and overlying serratus anterior and latissimus dorsi muscles visualized, then, 3ml lidocaine 1% will be used for skin and subcutaneous fat, using ultrasound guidance, a 38-mm 22-gauge regional block needle is going to be advanced in-plane at an angle of approximately 45 degrees towards the fifth rib. After aspiration to avoid intravascular injection 30ml of levobupivacaine 0.25% will be injected anteriorly to the rib and deep into the serratus anterior muscle.
Study: NCT05228145

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NGN-101
Description: Participants with confirmed mutations in the CLN5 gene who meet all the inclusion and none of the exclusion criteria will be treated with a single intracerebroventricular (ICV) dose and a single intravitreal (IVT) dose of the study treatment.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NGN-101
Description: Participants with confirmed mutations in the CLN5 gene who meet all the inclusion and none of the exclusion criteria will be treated with a single intracerebroventricular (ICV) dose and a single intravitreal (IVT) dose of the study treatment.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NGN-101
Description: Participants with confirmed mutations in the CLN5 gene who meet all the inclusion and none of the exclusion criteria will be treated with a single intracerebroventricular (ICV) dose and a single intravitreal (IVT) dose of the study treatment.