TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04972773

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness meditation (MM)
Description: Towards this additional MM practice, participants will be able to use any combination of the MM apps: Insight timer, which focuses on community/group-like therapy, Healthy minds, which focuses on resilience that is essential in disability adjustment, and Smiling mind, that reminds patients of their family/support structures. These three options were chosen for delivering free MM with different focuses that would cater to the variety of SCI patients needs. Participants will be alerted if they are not achieving 30 minutes of additional MM per week. This will guarantee that the treatment group have a higher time spent on MM for dose-response analysis. Participants will receive a reminder email (see attached) on the Sunday evening of a week with \<30 minutes of additional MM encouraging them to use their mindfulness app.
Study: NCT04999345

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Health education
Description: Health education and gross joint range of motion exercise for bilateral upper and lower extremities will be provided for those in the control group.
Study: NCT05507151

Intervention type: PROCEDURE
Intervention: Endoscopic Sleeve Gastroplasty
Description: endoscopic suturing of the stomach
Study: NCT05747872

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Buerger Allen Exercises
Description: These exercises are specific exercises aimed at improving circulation in the feet and legs.~While doing the exercises, first of all;~1. The legs are raised at an angle of 45 degrees and supported in this position for 1-3 minutes until the skin turns white.~2. Sit on the edge of the bed and let your legs hang down (make sure there is no pressure behind the knees). In this position, move your foot left and right and up and down for 3 minutes.~3. Lie on your back for 5 minutes keeping your legs warm with a blanket.~Performing all three of these exercises in sequence means 1 session. Exercises are done 2 times a day, at least 3 sessions each time.
Study: NCT05065840

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CDC 4 Pillars Program
Description: The CDC's 4 Pillars Transformation Program (4 Pillars Program) is a robust and empirically supported strategic approach that promotes the uptake of adult vaccinations and addresses facilitators and barriers at the patient, provider, and clinic level. This multi-level, evidence-based intervention has been successfully utilized to increase HPV vaccination in the general population and is primed to be tested in the high-risk HIV population, particularly PLWH in the rural South. This proposal seeks to expand the success of the 4 Pillars Program and tailor, refine, and implement in the HIV positive population who are at extraordinarily high risk for HPV-related cancers and can obtain the most benefit from the vaccine.
Study: NCT04554771

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tocilizumab 20 Mg/mL Intravenous Solution
Description: tocilizumab 8 mg/kg with a maximum of 800 mg intravenously on day 1, 15 and 29 of standard of care neoadjuvant chemoradiation

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tocilizumab 20 Mg/mL Intravenous Solution
Description: tocilizumab 8 mg/kg with a maximum of 800 mg intravenously on day 1, 15 and 29 of standard of care neoadjuvant chemoradiation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Paclitaxel 50 mg/m2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel 50 mg/m2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Paclitaxel 50 mg/m2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel 50 mg/m2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Carboplatin AUC = 2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin AUC = 2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Carboplatin AUC = 2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin AUC = 2 will be given intravenously on days 1, 8, 15, 22 and 29

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: External beam radiotherapy
Description: External beam radiotherapy will be delivered to a total dose of 41.4 Gy in 23 fractions of 1.8 Gy, 5 fractions per week starting the first day of the first cycle of chemotherapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: External beam radiotherapy
Description: External beam radiotherapy will be delivered to a total dose of 41.4 Gy in 23 fractions of 1.8 Gy, 5 fractions per week starting the first day of the first cycle of chemotherapy

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: External beam radiotherapy
Description: External beam radiotherapy will be delivered to a total dose of 41.4 Gy in 23 fractions of 1.8 Gy, 5 fractions per week starting the first day of the first cycle of chemotherapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: External beam radiotherapy
Description: External beam radiotherapy will be delivered to a total dose of 41.4 Gy in 23 fractions of 1.8 Gy, 5 fractions per week starting the first day of the first cycle of chemotherapy
Study: NCT04866901

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Slow-Paced Breathing (SPB)
Description: see arm description

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness (M)
Description: see arm description

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yogic Breathing (SPB+M)
Description: see arm description
Study: NCT06616623

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo tissue and blood sample collection
Study: NCT04792411

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation
Description: Multimodal, tailored prehabilitation programme
Study: NCT05933707

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: People with Metabolically Unhealthy Obesity - Low Calorie Diet
Description: Consumption of a low-calorie diet with caloric intake reduced by \~25% to achieve \~10% weight loss in about 4 to 5 months.
Study: NCT06183073

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: caudal block
Description: bupivacaine 0.25% in a dose of (1 ml / kg)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: dexmedetomidine 1μg/ kg.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TAP
Description: analgesia

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: bupivacaine 0.25% in a dose of (0.5 ml / kg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: bupivacaine 0.25% in a dose of (0.5 ml / kg
Study: NCT04903327

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVI-MSC
Description: COVI-MSC are allogeneic culture-expanded adipose-derived mesenchymal stem cells

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Excipient solution
Study: NCT06092515

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fermented High Zinc Wheat Flour Flatbread
Description: * Participants in this group will receive flatbreads made from fermented high zinc wheat flour.~* The flatbreads will be prepared using traditional fermentation methods.~* These flatbreads will be provided to participants to consume daily, along with vegetables or pulses (daal), for six days a week over the course of six months.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Unfermented High Zinc Wheat Flour Flatbread
Description: * Participants in this group will receive flatbreads made from unfermented high zinc wheat flour,~* The flatbreads will not undergo a fermentation process.~* These flatbreads will be provided to participants to consume daily, along with vegetables or pulses (daal), for six days a week over the course of six months.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Post-Harvest Fortified Whole Wheat Flour Flatbread
Description: * Participants in this group will receive flatbreads made from whole wheat flour fortified post-harvest~* These fortified flatbreads will be provided to participants for daily consumption, along with vegetables or pulses (daal), for six days a week over the course of six months.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Low Zinc Whole Wheat Flour Flatbread (Control Group)
Description: * Participants in this group will serve as the control group.~* They will receive flatbreads made from whole wheat flour with a low zinc content~* These low zinc flatbreads will be provided to participants for daily consumption, along with vegetables or pulses (daal), for six days a week over the course of six months. six days a week over the course of six months.
Study: NCT06616623

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vismodegib
Description: Given PO
Study: NCT06616740

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Cricoid pressure
Description: Cricoid pressure will be applied during LMA ProSeal insertion.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Paratracheal pressure
Description: Pratracheal pressure will be applied during LMA ProSeal insertion.
Study: NCT06661603

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GSY Yoga Intervention
Description: In the GSY yoga intervention, where participants received 90 minutes/week yoga intervention for duration of 10 weeks.
Study: NCT06676072

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PFA Ablation catheter
Description: Deliver RF and/or PF energy using the TactFlex PFA system
Study: NCT05116787

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BCX9930 monotherapy
Description: Administered orally twice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: BCX9930 monotherapy
Description: Administered orally twice daily
Study: NCT06749327

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High UPF, high hPDI diet
Description: High ultra-processed foods (UPFs) and healthy plant based diet

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Low UPF, high hPDI diet
Description: Low ultra-processed foods (UPFs) and high healthy plant-based diet
Study: NCT06751173

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Static Core Stability exercises
Description: i. Plank: Press the hands and knees to the floor with the back in a neutral position and wrists aligned directly under the shoulders.~ii. Side Plank: Lie on the side with knees bent and prop the upper body up on the elbow.~iii. Shoulder Bridge: Raise the pelvis off the floor until only the head, neck, shoulders, and feet are touching the mat. Place the hands at the waist.~iv. Static Crunch: Lie on the back with feet flat on the floor and knees bent at a 90-degree angle.~v. Leg Lift: Lie straight on the floor, keep the arms at the sides, and slowly lift both legs into the air.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mckenzie exercises
Description: i. Prone Extension (Positioned): Lie on the stomach with pillows placed under the chest for comfort.~ii. Prone Extension on Elbow: Keep the back and buttocks relaxed and rise up on the elbows as high as possible.~iii. Prone Press-ups: Place the hands beside the shoulders. Keep the back and buttocks relaxed, and use the arms to press up.~iv. Standing Extension: Stand with feet apart and hands on the small of the back with fingers pointing backward. Bend backward at the waist, supporting the trunk with the hands.~v. Side glide in Standing: Stand at a right angle to the wall about 2 feet away. Lean the shoulder into the wall.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Mobilization
Description: Central-Unilateral posterio anterior and lateral glide

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal Mobilization
Description: Central-Unilateral posterio anterior and lateral glide
Study: NCT06754735

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Topical Wound Oxygen Therapy
Description: The active intervention is the application of the Topical Wound Oxygen device that supplies cyclical oxygen pressure directly to the wound site within a sealed environment.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Control Topical Wound Oxygen
Description: The sham control intervention is the application of Topical Wound Oxygen device that supplies topical room air to the wound site within a sealed environment.
Study: NCT06756321

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-CD19-CAR T-cells, or anti-CD30-CAR T-cells, or anti-CD20/CD30-CAR T-cells
Description: Each subject will be infused with single dose. A classic 3+3 dose escalation will be employed.~anti-CD19-CAR T-cells~Dose level 1：1x10\^5 CAR T cells/kg, Dose level 2：3x10\^5 CAR T cells/kg, Dose level 3：1x10\^6 CAR T cells/kg~anti-CD30-CAR T-cells~Dose level 1：3x10\^6 CAR T cells/kg, Dose level 2：6x10\^6 CAR T cells/kg, Dose level 3：1x10\^7 CAR T cells/kg~anti-CD20/CD30-CAR T-cells~Dose level 1：1x10\^6 CAR T cells/kg, Dose level 2：3x10\^6 CAR T cells/kg, Dose level 3：1x10\^7 CAR T cells/kg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Fludarabine will be given at a dose of 25 mg/m\^2/day intravenously (IV) for 3 days prior to the infusion of CAR T-cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Cyclophosphamide will be given at a dose of 250 mg/m\^2/day intravenously (IV) for 3 days prior to the infusion of CAR T-cells.
Study: NCT06758102

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dance Program
Description: A 12-week, virtual dance program consisting of seated and standing choreography and contemporary style elements will be taught by a certified dance instructor. Sessions will be conducted by the HIPAA-compliant, video-conferencing platform, Zoom.
Study: NCT06756659

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Center-based exercise training
Description: All participants will undergo a spot jogging cardiopulmonary exercise test and a six-minute walking test. The outpatient center-based cardiac rehabilitation group will perform moderate-intensity stationary biking or treadmill exercise for 30 minutes, twice a week, under the supervision of a physical therapist in the outpatient cardiac rehabilitation room.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based spot jogging
Description: The home-based spot jogging cardiac rehabilitation group will receive exercise intensity guidance in the outpatient cardiac rehabilitation room for 30 minutes of spot jogging and treadmill exercise during the first, fourth, and seventh weeks. They will then perform moderate-intensity spot jogging at home for 30 minutes, twice a week, at a perceived exertion level of 13 out of 20 on the RPE scale.
Study: NCT06758089

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens 1 (ocufilcon D)
Description: 15 minutes of daily wear

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens 2 (somofilcon A)
Description: 15 minutes of daily wear
Study: NCT06757062

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kinesiology Tape
Description: The kinesiology tape (KT) is applied with the dorsal application for the treatment of carpal tunnel syndrome (CTS). This method is utilized and explained in Krause et al. (2020). This study will assess the efficacy of the application method as well as the varying effects of the color of the KT. Red KT will be compared to skin tone KT. The skin tone KT will be color-matched as closely as possible to each participant's skin tone to reduce the effect of the KT color. In this way, the study's second purpose is to understand the potential effect of color on psychological function and performance in the context of aggressive first-person shooter esports games.
Study: NCT05703087

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive cueing in the information video before a primary TKA
Description: Two weeks before the surgery, in the outpatient clinic (during their preoperative appointment), the pre-surgery information video was shown to the patients. Patients were randomly allocated to either the positive cueing group (intervention) or the standard care group (control) with Castor EDC (14) using a variable block randomization model. Patients did not know whether they watched the adapted video or the standard video.
Study: NCT05622487

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neural Therapy
Description: Neural therapy is a form of treatment that aims to act on the autonomic nervous system, by injecting local anesthetics into certain parts of the body.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio taping
Description: Kinesiotape is used for injury prevention, rehabilitation and performance enhancement. It has been shown to be clinically effective in increasing joint movements, increasing muscle activity, inducing muscle maximum torque earlier, and improving functional performance
Study: NCT05314803

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yoga
Description: Participants receive the yoga program, which is delivered by a trained yoga instructor (completed at least a 200-hour yoga teacher training, Yoga Thrive Teacher Training Certification (or similar), and/or practical experience working with individuals affected by cancer). The first class of the week is comprised of 45 minutes of gentle, progressive, hatha-based yoga sequencing and postures with the last 15 minutes focused on guided behaviour change and mindfulness techniques that varies week-to-week, based on the participants in the class. The second class of the week is 60 minutes of gentle, yin-based yoga sequencing and postures with an element of opening and relaxing.
Study: NCT05805891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bortezomib
Description: bortezomib 2mg/week subcutaneous injection
Study: NCT05671588

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Controlled combined exercise group
Description: Patients will undergo protocol-defined combined aerobic-resistant therapy on a cycling ergometer and multifunctional fitness device

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional rehabilitation
Description: Patients will undergo conventional rehabilitation.
Study: NCT04916795

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vupanorsen
Description: 80 mg subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vupanorsen
Description: 80 mg subcutaneous injection
Study: NCT05912699

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Slimbiotics Postbiotic
Description: SlimBiotics postbiotic formula contains the following ingredients:~* Heat-inactivated L. fermentum K8 Postbiotic.~* Microcrystalline cellulose.
Study: NCT05958680

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ASDactive
Description: An integrated theory-based intervention to promote habitual physical activity behaviours in autistic youth
Study: NCT06757062

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Kinesiology Tape
Description: The kinesiology tape (KT) is applied with the dorsal application for the treatment of carpal tunnel syndrome (CTS). This method is utilized and explained in Krause et al. (2020). This study will assess the efficacy of the application method as well as the varying effects of the color of the KT. Red KT will be compared to skin tone KT. The skin tone KT will be color-matched as closely as possible to each participant's skin tone to reduce the effect of the KT color. In this way, the study's second purpose is to understand the potential effect of color on psychological function and performance in the context of aggressive first-person shooter esports games.
Study: NCT06756854

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Biologic Agent: injectable platelet rich fibrin.
Description: injection of I-PRF to thin gingival phenotype 3 times with 7 days interval between sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: injecable platelet rich fibrin, and low level laser therapy radiation.
Description: injection of I-PRF+ exposure to LLLT to thin gingival phenotype 3 times with 7 days interval between sessions.
Study: NCT06756815

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross bracing and conservative treatment
Description: Week Exercise Training Frequency (sets x reps) Week 1-2 1. Cross Bracing (Isometric Holds) 2. Quad Sets 3. Straight Leg Raise 4. Ankle Pumps 5. Heel and Toe Raises 6. Glute Bridge 2 sets x 10 reps Week 3-4 1. Cross Bracing (Isometric Holds) 2. Hamstring Curls 3. Step-ups 4. Mini Squats (with support) 5. Leg Press 6. Lateral Leg Raises 3 sets x 12 reps Week 5-6 1. Cross Bracing (Isometric Holds) 2. Single-leg Balance (with support) 3. Lunges (with proper technique) 4. Squats (bodyweight) 5. Box Jumps 6. Lateral Step-ups 3 sets x 15 reps

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross bracing and DNS with conservative treatment
Description: Week Exercise Training Frequency (sets x reps) Week 1-2~1. Cross Bracing (Isometric Holds)~2. DNS Core Activation (supine, prone positions)~3. Quad Sets~4. Straight Leg Raise~5. Ankle Pumps~6. Heel and Toe Raises~7. Glute Bridge 2 sets x 10 reps Week 3-4~1. Cross Bracing (Isometric Holds) 2. DNS Core Stabilization (advanced activation) 3. Hamstring Curls 4. Step-ups 5. Mini Squats 6. Leg Press 7. Lateral Leg Raises 8. Pelvic Tilts 3 sets x 12 reps Week 5-6~1. Cross Bracing (Isometric Holds)~2. DNS Dynamic Stabilization (with resistance)~3. Single-leg Balance (with and without support)~4. Lunges (with added resistance)~5. Squats (bodyweight or weighted)~6. Box Jumps~7. Lateral Step-ups~8. Running Drills (if tolerated) 3 sets x 15 reps