TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05989581

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Labetalol or Nifedipine
Description: The choice of anti-HTN will be based on the patient and provider's experience and preference. First line anti-HTN recommended in pregnancy- labetalol or nifedipine- will be administered to patients. At least weekly, a study team member will review the participants' BPs and, if randomized to intervention and a higher dose is needed to maintain BPs \<130/80 mmHg, the study team member will communicate with the clinical team, led by a University of Alabama Maternal Fetal Medicine Attending, in order to ensure coordination between the research and clinical care teams. Labetalol will be initiated at 200 mg twice daily and escalated in 200mg /dose daily until BP\<130/80mmHg to a maximum dose of 2400mg/day. Procardia will be initiated at 30mg XL once daily and uptitrated in 30mg increments until a maximum dose of 120mg daily. Postpartum, titration will occur in similar fashion. The patient will be transitioned to her primary care provider for BP management after the 6-week postpartum visit.
Study: NCT06283017

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hypoglossal nerve stimulation
Description: Device stimulation of the hypoglossal nerve
Study: NCT04804137

Intervention type: OTHER
Intervention: Blood
Description: Blood samples are taken at each visit to the day hospital for a programmed injection of immunotherapy.

Intervention type: OTHER
Intervention: sputum
Description: induced by saline aerosol sputum during each visit to the day hospital for a programmed injection of immunotherapy.

Intervention type: OTHER
Intervention: saliva
Description: spontaneous saliva during each visit to the day hospital for a programmed injection of immunotherapy.

Intervention type: OTHER
Intervention: stool
Description: Stool analyses will be carried out on a sample taken by the patient at home and brought back at the time of a day hospital.
Study: NCT05238662

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pedicle screw fixation on one side and intervertebral cage on the other sided
Description: pedicle screw fixation on one side and intervertebral cage on the other sided

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pedicle screw fixation and interbody cage on the same side
Description: pedicle screw fixation and interbody cage on the same side
Study: NCT06057064

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological: AZD3152
Description: 300 mg single dose of AZD3152 IM

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Biological: Placebo
Description: Single dose of Placebo IM (0.9% sodium chloride)
Study: NCT05803460

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stage 1 Experimental A group: actual natural environment
Description: Participants will go to the park and sit still for 20 minutes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stage 1 Experimental B group: virtual reality natural environment
Description: Participants will experience the virtual reality natural environment by the researcher for 20 minutes

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stage 1 Control group: city environment
Description: Participants will sit still for 20 minutes in a city environment.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Stage 2 group
Description: tree element virtual natural environment and tree and water element virtual natural environment experiences

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stage 3 Experimental group: virtual reality natural environment
Description: virtual reality natural environment programs for 2 time a week (40 mins/ every week) and 8weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stage 3 Control group: routine care
Description: Control group received routine care last for 8 weeks.
Study: NCT01240382

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3% DE-089 ophthalmic solution

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.1% sodium hyaluronate ophthalmic solution
Study: NCT04617821

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel plus gemcitabine
Description: Albumin-bound paclitaxel and gemcitabine are given intravenous infusion, repeated every 4 weeks for 1, 8, and 15 days, for a total of 4 to 6 cycle.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: mFOLFIRINOX
Description: Intravenous oxaliplatin for 2 hours, day 1;Intravenous infusion of calcium formyl tetrahydrofolate (LV) for 2 h, day 1;Irinotecan intravenous infusion is added 30 minutes later for 90 minutes, day 1;Intravenous infusion of 5-fluorouracil (5-FU) continued for 46 hours.Repeat every 2 weeks for a total of 4-6 cycles.
Study: NCT06275269

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-Guided
Description: Ultrasound-Guided Triamcinolone Injection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Translaryngeal Endoscopic Mucosal Injection
Description: Translaryngeal Endoscopic Mucosal Injection of Triamcinolone
Study: NCT06228404

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enhanced autologous PSMA-CAR T
Description: 3 escalated dosing cohorts are designed to explore safety and efficacy of enhanced autologous PSMA-CAR T:~cohort A： CART-PSMA cells 0.25×106/kgBW, following lymphodepleting chemotherapy with cyclophosphamide 300 mg/m2/day and fludarabine 30 mg/m2/day given according to protocol;~cohort B： CART-PSMA cells 0.75×106/kgBW，following lymphodepleting chemotherapy with cyclophosphamide 300 mg/m2/day and fludarabine 30 mg/m2/day given according to protocol;~cohort C： CART-PSMA cells 2×106/kgBW，following lymphodepleting chemotherapy with cyclophosphamide 300 mg/m2/day and fludarabine 30 mg/m2/day given according to protocol;
Study: NCT05138146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 609A
Description: 609A 200mg,IV, Day 1of each treatment cycle, up to disease progression or intolerable toxicity, death, early withdrawal from the study or loss to follow-up, withdrawal of consent, or the end of the treatment period, whichever occurs first.~Every 3 weeks a treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: doxorubicin hydrochloride
Description: 60mg/m2 or 75mg/m2, IV, Day1of the1-6th treatment cycles only. Every 3 weeks a treatment cycle.
Study: NCT05652777

Intervention type: DEVICE
Intervention: NeoSpot
Description: Pregnant women will undergo screening of their vital signs using the NeoSpot device.
Study: NCT06393231

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: acupuncture
Description: Acupuncture is applied to ST8, GB14, BL12, SJ23, ST2, SI18, ST4, ST7, RN24, Ex-HN16, SJ17 and LI4 on the affected side and needles are retained for half an hour.Add infrared irradiation therapy in the same time

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: acupuncture
Description: Acupuncture is applied to ST8, GB14, BL12, SJ23, ST2, SI18, ST4, ST7, RN24, Ex-HN16, SJ17 and LI4 on the affected side and needles are retained for half an hour.Add infrared irradiation therapy in the same time
Study: NCT05922059

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous vagus nerve stimulation
Description: Auricular transcutaneous vagus nerve stimulation will be used in the left cavity of the external ear with a stimulation frequency of 20-30 Hz for half hour. Monophasic rectangular waveforms will be used, and the intensity will be adjusted below the patient's pain threshold.
Study: NCT06405893

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Mindful breathing exercise
Description: Participants do a 10 minute guided mindful breathing exercise or participants do listen to a 10 minute control recording

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindful breathing exercise
Description: Participants do a 10 minute guided mindful breathing exercise or participants do listen to a 10 minute control recording
Study: NCT06523127

Intervention type: OTHER
Intervention: Recording data from the ICU stay and the post-ICU follow-up.
Description: Record analysis of the post-ICU follow-up with the Interpretative Phenomenological Analysis

Intervention type: OTHER
Intervention: Recording data from the ICU stay and the post-ICU follow-up.
Description: Record analysis of the post-ICU follow-up with the Interpretative Phenomenological Analysis
Study: NCT05394168

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HLX53
Description: There are 5 preset dose groups, namely 30mg/QW, 150mg/QW, 400mg/QW, 1000mg/Q3W and 2000mg/Q3W, administered by intravenous infusion.
Study: NCT05489575

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active CPAP
Description: Continuous positive airway pressure (CPAP) is applied at 8, 10, or 12 cm H20. The active CPAP level will be determined during a CPAP titration trial

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active CPAP
Description: Continuous positive airway pressure (CPAP) is applied at 8, 10, or 12 cm H20. The active CPAP level will be determined during a CPAP titration trial

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham CPAP
Description: Sham continuous positive airway pressure applied at \<4 cm H2O

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham CPAP
Description: Sham continuous positive airway pressure applied at \<4 cm H2O

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sleeping in a head-up tilt (HUT) position
Description: Sleeping with the whole bed tilted head-up by 10 degrees or with the head elevated by 13-14 inches.
Study: NCT05246449

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: individualised treatment plan (VitalCare) and associated remote medical monitoring
Description: VitalCare is a treatment plan to help in the personalisation of patient care.
Study: NCT04960267

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of pre-peritoneal drainage after rTAPP
Description: Use of pre-peritoneal drainage after rTAPP
Study: NCT05518721

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hallux Rigidus Treatment
Description: Participants will receive either a synthetic cartilage implant or dermal interposition arthroplasty

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hallux Rigidus Treatment
Description: Participants will receive either a synthetic cartilage implant or dermal interposition arthroplasty
Study: NCT05508958

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior approach
Description: Anterior approach

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Posterolateral approach
Description: Posterolateral approach
Study: NCT06473441

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Rehabilitation Therapy
Description: Twice-weekly sessions with remote supervision and guidance from therapists.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Rehabilitation Therapy
Description: Twice-weekly sessions with remote supervision and guidance from therapists.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education
Description: Health education based on individual assessments.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education
Description: Health education based on individual assessments.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education
Description: Health education based on individual assessments.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Prescription
Description: Exercise prescription tailored to individual needs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Prescription
Description: Exercise prescription tailored to individual needs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Prescription
Description: Exercise prescription tailored to individual needs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Exercise Equipment Use
Description: Use of a home exercise bike, resistance bands, respiratory muscle training device, and a portable heart rate monitor.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Exercise Equipment Use
Description: Use of a home exercise bike, resistance bands, respiratory muscle training device, and a portable heart rate monitor.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Exercise Equipment Use
Description: Use of a home exercise bike, resistance bands, respiratory muscle training device, and a portable heart rate monitor.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Log
Description: Logging daily exercise intensity and duration in a rehabilitation diary

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Log
Description: Logging daily exercise intensity and duration in a rehabilitation diary

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Log
Description: Logging daily exercise intensity and duration in a rehabilitation diary

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Follow-Up Calls
Description: Regular follow-up calls to monitor progress and address any issues.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Follow-Up Calls
Description: Regular follow-up calls to monitor progress and address any issues.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Follow-Up Calls
Description: Regular follow-up calls to monitor progress and address any issues.
Study: NCT05024279

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Left bundle branch area pacing
Description: Left bundle branch area pacing will be applied as established in the literature using commercially available equipment.~In case of unsuccessful application of left bundle branch area pacing, cross-over to right ventricular pacing is allowed.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Right ventricular pacing
Description: Right ventricular pacing as the standard, established form of pacing will be applied in the control group. No cross-over to the intervention arm is anticipated.
Study: NCT06550492

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: smoke filtering electrocautery device
Description: A smoke-filtering electrocautery device was used during surgery.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: double mask
Description: A double-layer mask was used during the operation.
Study: NCT05922059

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Heart rate variability biofeedback
Description: The patient will receive visual HRV feedback during resonance frequency breathing. Finally, the patient will be instructed to maximize their peak-to-peak HRV and attain the phase between respiration and HRV changes as closely as possible

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard-care physiotherapy
Description: consists of cervical mobilization on the painful segment, isometric exercise for neck flexors, and a combination of strengthening and stretching exercises from sitting position; cervical extensors strengthening exercise using red color Thera-band and stretching exercises upper trapezius of the painful side.
Study: NCT05103787

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: deep parasternal intercostal plane block
Description: Twenty milliliters of 0.25% bupivacaine will be placed bilaterally in the fascial plane between internal intercostal muscle and transversus thoracis muscle at intercostal space 4 or 5, lateral from sternum, with ultrasound guidance using high-frequency linear transducer.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: deep parasternal intercostal plane block
Description: Twenty milliliters of 0.25% bupivacaine will be placed bilaterally in the fascial plane between internal intercostal muscle and transversus thoracis muscle at intercostal space 4 or 5, lateral from sternum, with ultrasound guidance using high-frequency linear transducer.
Study: NCT05318651

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kwit SAS - smoking cessation app
Description: Kwit is a mobile app for smoking cessation. Different CBT techniques are used by the app already been proved as effective : Case analysis craving tool, Achievements badges,Diary, Goal (outcome) setting, A 9-steps preparation program, psychological education, Emotional monitoring, Access to groups on social networks, different strategies ( NRT/water/meditation), Motivational cards.
Study: NCT05704556

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-548
Description: Tablets for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-548
Description: Tablets for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-548
Description: Tablets for oral administration.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-548
Description: Tablets for oral administration.
Study: NCT05153265

Intervention type: OTHER
Intervention: Survey
Description: There will be no interventions for study participants. Participants will be asked to complete a survey.

Intervention type: OTHER
Intervention: Survey
Description: There will be no interventions for study participants. Participants will be asked to complete a survey.
Study: NCT06076785

Intervention type: DEVICE
Intervention: OdySight
Description: At home measurements of visual acuity through a mobile app.
Study: NCT05485311

Intervention type: OTHER
Intervention: visual analog scale
Description: Data collection was carried out at all stages of treatment: medical and nursing brigade, military mobile hospital, military medical clinical center, during rehabilitation, within 12 months of the injury.

Intervention type: OTHER
Intervention: visual analog scale
Description: Data collection was carried out at all stages of treatment: medical and nursing brigade, military mobile hospital, military medical clinical center, during rehabilitation, within 12 months of the injury.
Study: NCT05103787

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: control
Description: Skin puncture with needle will be performed on the same location as the treatment group without administration of local anesthetics.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: Skin puncture with needle will be performed on the same location as the treatment group without administration of local anesthetics.
Study: NCT05406323

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-Based Fall Prevention Program
Description: Health education: This intervention consisted of seven health issues which are Fall among elderly, fall risk factors,  fall prevention interventions-exercise,  fall prevention interventions-healthy diet,  fall prevention interventions- drug use, fall prevention interventions- vision, fear of falling.~Exercise: This intervention is the exercise that is a combination of balance and strengthening exercises (8 exercise). Participants will do the exercises at least three days a week (along 6 week).~Safe home environment: This intervention is aimed at providing a fall-safe home environment for the participants. In this context, the participants will watch the video on creating a safe home environment for falling. Participants will also be asked to answer the Home Safety Check Form for Falls to make their home more fall-proof. In this form, according to the answers given by the participants, suggestions will be given to prevent the risks of falling in the home environment.
Study: NCT05774314

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community Health Worker Intervention
Description: Communities that are randomized into the Treatment arm will receive the Flourish program. Communities with a Flourish program will select and train a Community Health Worker from the Transform program participants. At the end of the Transform program, a Savings Group will be formed from the Transform program participants. The Savings Group will nominate households to participate in the Flourish program and research study. The Community Health Worker will approach the nominees and attempt to enroll them into the Flourish program and research study. If the nominees agree to be enrolled in the Flourish program, the Community Health worker will provide screening, referral, counseling, and treatment services to the household for the duration of the study.
Study: NCT06516770

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation
Description: The subject will receive the tDCS using 5X7 cm electrodes. The anodal electrode will be placed on M1 representing the back muscles (1 cm anterior and 4 cm lateral to the vertex), while cathodal electrode will be placed on contralateral supraorbital area. The intensity will be set at 2 mA with 10-second fade in/out. The subject will be stimulated by tDCS for 20 minutes

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neuromuscular electrical stimulation
Description: The participants will receive the NMES using interferential mode (6000 Hz, beat frequency 20-50 Hz, scanning effect) on bilateral LM. The intensity will be set at the subject's maximum tolerance. Stimulation will be set at 10 seconds on and 60 seconds off to minimize muscle fatigue. The total NMES time is 20 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor control exercise
Description: The participant will be instructed to perform co-contraction of transverse abdominis and lumbar multifidus muscle, while performing self-selected pace forward bend. Emphasis will be given to move in control manner (smooth and symmetrical movement). The participant will perform 4 minutes of continuous movement for 4 sets with 1 minute rest between sets.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isometric exercise
Description: The participant will be instructed to perform isometric back extension exercise in modified Sorensen position. The participant will hold 60 seconds in neutral position for 5 repetitions with 3 minutes rest between repetitions.
Study: NCT04429958

Intervention type: OTHER
Intervention: GDM
Description: different degrees of hyperglycaemia during pregnancy
Study: NCT06296511

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 60 min of treadmill exercise performed at 70% of peak oxygen uptake.
Study: NCT05109715

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Continued ventilation
Description: Ventilation is continued from going on CPB until clamping of the ascending aorta with tidal volume 3ml/kg ideal body weight, Fraction of inspired oxygen (FiO2) 50%, respiratory rate 5/min and Inspiratory:Expiratory (I/E) ratio 1/2.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Discontinued ventilation
Description: Ventilation is discontinued after going on CPB and lungs are exposed to atmospheric pressure