TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05566041

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RRx-001 + eLOOP Device
Description: RRx-001 is a small molecule anticancer drug which is mixed with patient's own blood using the eLOOP device~Drug: Cisplatin/carboplatin plus etoposide Standard of care platinum doublet chemotherapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin/carboplatin plus etoposide
Description: Standard of care platinum doublet chemotherapy
Study: NCT06367205

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goal-Directed Fluid Therapy (GDFT)
Description: Norepinephrine will be administered intravenously at a rate of 0.06 µg/kg/min, followed by the implementation of fluid therapy guided by SVV until reaching our target. In instances where SVV ≤ 13%, indicative of adequate effective circulating blood volume, the fluid infusion rate will be adjusted to 1 ml/kg/h. Conversely, if SVV \> 13%, denoting inadequate effective circulating blood volume, a rapid infusion of 1 ml/kg of crystalloid fluid will be administered over 2 minutes, with subsequent observation of fluid reactivity after a further 2-minute interval. This process is reiterated until SVV ≤ 13% is attained. Should SVV \> 13% recurs during surgery, the aforementioned intervention is repeated.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Regular Fluid Therapy
Description: Anesthesiologists will rely on their clinical expertise and intraoperative circulatory hemodynamic assessment to regulate fluid infusion rates and administer medications as necessary
Study: NCT04732806

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mightier video games
Description: Biofeedback video game play in home
Study: NCT05612490

Intervention type: DRUG
Intervention: Furosemide stress test
Description: The FST corresponds to the intravenous single-dose administration of 1 mg/kg (1.5 mg/kg in previously exposed patients) of furosemide and the assessment of resulting diuresis in the following two hours. In the 12 hours following the first RRT liberation, a FST will be performed. The test will be considered positive if urinary output is ≥200 mL in the two hours following furosemide administration.
Study: NCT05251051

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: pediatric physical therapy
Description: Pediatric physical therapists will provide weekly home therapy using standard of care/best evidence procedures

Intervention type: OTHER
Group type: OTHER
Intervention: Care Coordination
Description: A navigator will be assigned who will assist families in obtaining Early Intervention services and other therapy services if needed

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care Coordination
Description: A navigator will be assigned who will assist families in obtaining Early Intervention services and other therapy services if needed
Study: NCT04919265

Intervention type: OTHER
Intervention: No intervention - mother-infant cohort study
Description: There are no interventions because it is a mother-infant cohort study
Study: NCT05872022

Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study, therefore no intervention is used.

Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study, therefore no intervention is used.
Study: NCT04319510

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Craniosacral therapy
Description: The first experimental group of patients will receive 24 units à 45 minutes over 12 weeks (2 consecutive units per week) offered by a trained craniosacral therapist within a 1:1 setting. Treatment as usual is allowed.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Craniosacral self-help group training
Description: The second experimental group of patients will receive 24 teaching units (TUs) à 45 minutes over 12 weeks offered by a trained craniosacral therapist within a group setting. The group training will start with an introductory day (8 TUs), followed by 6 practice evenings every two weeks (2 TUs each) and a final afternoon (4 TUs). The patients have to agree to participate in the introductory day and 90% of the following TUs. All patients will receive a script with theoretical CST information and descriptions of the learned techniques, which should facilitate the correct practice at home. Treatment as usual is allowed.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Treatment as usal / wait list
Description: The control group will receive no specific study treatment for a waiting period of six months. Treatment as usual is allowed. Afterwards they were offered 2 treatments (4TUS) of 1:1 CST and the participation in the group training.
Study: NCT05011760

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Baseline [C-11]NPA PET Scan
Description: Radiotracer

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: d-amphetamine
Description: Oral, 0.5 mg/Kg

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Post-amphetamine [C-11]NPA PET Scan
Description: Radiotracer
Study: NCT06043739

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Filgotinib
Description: Commercially developed film-coated tablet administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Filgotinib
Description: Film-coated mini-tablets administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Filgotinib
Description: Film-coated mini-tablets administered orally
Study: NCT05368662

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality of life and sleep questionnaire
Description: Evaluation of quality of life and quality of sleep by questionnaires
Study: NCT06109870

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PRECEDE-PROCEED
Description: delivered self-sampling (CHWSS) to increase screening participation.
Study: NCT06646185

Intervention type: OTHER
Group type: OTHER
Intervention: Menstrual Cups
Description: Participants adopt menstrual cups to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.

Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.

Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.

Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.
Study: NCT05460819

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture treatment
Description: Acupoint selection: Hegu-Yinxi acupoint group (clearing heat and relieving sweat), Sanyinjiao-Fuliu acupoint group (nourishing yin and tonifying kidney), Tianshu-uteri acupoint group (special effect points) (12 acupoints on both sides).~Frequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.~Operation: Use a one-time sterile acupuncture needle (0.30×40mm, Huatuo brand), insert the needle 0.5 inch along the anatomical position, level up and relieve the qi, and keep the needle for 20 minutes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Acupuncture treatment
Description: Selecting acupoints: Select the side opening positions of the 6 acupuncture points in the real acupuncture group, and select non-meridian and non-points (points with less nerve distribution, sparseness, and rich muscles).~Frequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.~Operation: ① Shallow needling scheme: use a disposable sterile acupuncture needle, insert the needle 0.2 inch, without twisting, and keep the needle for 20 minutes. ②Non-invasive acupuncture plan: choose a special comfort needle with no needle tip at the top of the needle, paste a disposable sterile foam pad on the non-acupoint, and use a disposable sterile flat head The acupuncture needles were pierced into the foam pad, lightly touching but not piercing the skin, and not breathing; the needles were kept for 20 minutes.
Study: NCT06258499

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: BHA
Description: BHA active ingredients include a blood-derived component and beta-tricalcium phosphate. It is manually placed into the joint fusion space during fusion surgery.
Study: NCT06646185

Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.

Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.
Study: NCT06491147

Intervention type: OTHER
Intervention: Emergency front of neck access
Description: The algorithm in the DAS manual will be explained. Following this, the researcher will demonstrate the scalpel spark plug technique with a 4-step approach that is frequently used in skill teaching.~In step 1 of this approach, the technique will be demonstrated without any verbal explanation.~In the 2nd step, the technique will be demonstrated with verbal expression. In the 3rd step, the participant will be asked to have the trainer do it. In the 4th and last step, the participant will apply eFONA from start to finish.

Intervention type: OTHER
Intervention: Emergency front of neck access
Description: The algorithm in the DAS manual will be explained. Following this, the researcher will demonstrate the scalpel spark plug technique with a 4-step approach that is frequently used in skill teaching.~In step 1 of this approach, the technique will be demonstrated without any verbal explanation.~In the 2nd step, the technique will be demonstrated with verbal expression. In the 3rd step, the participant will be asked to have the trainer do it. In the 4th and last step, the participant will apply eFONA from start to finish.
Study: NCT05542537

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brighter Bites (BB) Produce Distribution
Description: For 16 weeks in the school year, teachers in participating program schools will receive distributions of 8-10 different types of produce items.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brighter Bites (BB) Nutrition Education
Description: Brighter Bites Nutrition Education will consist of recipes, food preparation and storage ideas, and tips and tools to budget and plan meals. Teachers will be trained in a nutrition education curriculum, which will be implemented in the program schools as part of the BB program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Create Healthy Futures (CHF) Weekly Wellness Groups
Description: Peer-facilitators will lead virtual weekly group discussions. Penn State Better Kid Care will train the wellness facilitators.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Create Healthy Futures (CHF) Web-Based Module
Description: Create Healthy Futures Web-Based Module is self-paced and focuses on the following topics: 1) Introduction, 2) Challenges of the food environment, 3) Nutrition and your health, 4) Food culture reform, and 5) Providers' role in creating healthy futures. The Create Healthy Futures module utilizes several educational methods to increase interactivity and engagement, including video footage of content experts, reflection activities, downloadable handouts, and action planning. Each chapter takes approximately 30-40 minutes to complete. The program is delivered on the Better Kid Care On Demand platform, an asynchronous learning management system that provides professional development training for teachers in all 50 states and 69 countries.
Study: NCT06646185

Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.
Study: NCT06647277

Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: Fecal Microbiota Transplant
Description: Fecal Microbiota Transplant
Study: NCT05472272

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Formula diet
Description: Participants will receive a low-calorie (815-835 kcal/day; approximately 43% carbohydrate, 29% protein, and 29% fat) formula diet product for 12 weeks, followed by a gradual food reintroduction phase combined with physical activity support for 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food-based diet
Description: Participants will receive a low-calorie (815-835 kcal/day; 45-50% carbohydrate, 20-30% protein, and 20-30% fat) food-based diet created by dietitians for 12 weeks. After 12 weeks, participants will increase energy intake gradually and be encouraged to increase daily physical activity to maintain weight loss for another 12 weeks.
Study: NCT05074940

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amivantamab
Description: Patients will receive amivantamab at 1050mg weekly for the first cycle and biweekly thereafter (1400mg for patients ≥80kg).
Study: NCT05542537

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Create Healthy Futures (CHF) Web-Based Module
Description: Create Healthy Futures Web-Based Module is self-paced and focuses on the following topics: 1) Introduction, 2) Challenges of the food environment, 3) Nutrition and your health, 4) Food culture reform, and 5) Providers' role in creating healthy futures. The Create Healthy Futures module utilizes several educational methods to increase interactivity and engagement, including video footage of content experts, reflection activities, downloadable handouts, and action planning. Each chapter takes approximately 30-40 minutes to complete. The program is delivered on the Better Kid Care On Demand platform, an asynchronous learning management system that provides professional development training for teachers in all 50 states and 69 countries.
Study: NCT06491147

Intervention type: OTHER
Intervention: Emergency front of neck access
Description: The algorithm in the DAS manual will be explained. Following this, the researcher will demonstrate the scalpel spark plug technique with a 4-step approach that is frequently used in skill teaching.~In step 1 of this approach, the technique will be demonstrated without any verbal explanation.~In the 2nd step, the technique will be demonstrated with verbal expression. In the 3rd step, the participant will be asked to have the trainer do it. In the 4th and last step, the participant will apply eFONA from start to finish.

Intervention type: OTHER
Intervention: Emergency front of neck access
Description: The algorithm in the DAS manual will be explained. Following this, the researcher will demonstrate the scalpel spark plug technique with a 4-step approach that is frequently used in skill teaching.~In step 1 of this approach, the technique will be demonstrated without any verbal explanation.~In the 2nd step, the technique will be demonstrated with verbal expression. In the 3rd step, the participant will be asked to have the trainer do it. In the 4th and last step, the participant will apply eFONA from start to finish.

Intervention type: OTHER
Intervention: Emergency front of neck access
Description: The algorithm in the DAS manual will be explained. Following this, the researcher will demonstrate the scalpel spark plug technique with a 4-step approach that is frequently used in skill teaching.~In step 1 of this approach, the technique will be demonstrated without any verbal explanation.~In the 2nd step, the technique will be demonstrated with verbal expression. In the 3rd step, the participant will be asked to have the trainer do it. In the 4th and last step, the participant will apply eFONA from start to finish.
Study: NCT06209879

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYSTANE™ Hydration Lubricant Eye Drops
Description: SYSTANE™ Hydration Lubricant Eye Drops (Hyaluronic Acid \[HA\] 0.15%; Polyethylene Glycol 400 0.4%; Propylene Glycol 0.3%)1-2 drops 4 times a day) and 0.1% FML (1-2 drops 3 times a day) in both eyes for 12 week
Study: NCT05809752

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dendritic Cell Vaccine
Description: Intrathecal (IT) dendritic cell vaccine (DCV) will be administered once every week. As per standard procedures of IT chemotherapy or antibody administration it is administered over 5 -10 minutes or at 1 ml/minute while monitoring the patient under sterile conditions. In general, to assure delivery of the DCVs into the ventricular space and compensate for dead space in the Ommaya, the delivery of IT DCV cells is followed by the administration of 2.5 mls of saline. In general there is a maximum volume of 10 mls of DCVs.
Study: NCT06224816

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Custom 3D mask (3DM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received 3D mask during 4 hour, then crossed over to traditional mask.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Custom 3D mask (3DM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received 3D mask during 4 hour, then crossed over to traditional mask.
Study: NCT05240716

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FES program
Description: 8 weeks intervention. 3 sessions per week. Previous to the intervention, volunteers will familiarize with the electrical stimulation by receiving three trials of the stimuli. Electrical current intensity will be set for each volunteers, with the capacity of generating a muscle contraction without inducing discomfort in the volunteer. During the FES program, patient in standing position will perform a step, while electrical current stimulation will be applied to the skin over the tibial nerve on the contralateral of the stimulation side. The FES will be delivered during the paretic plantarflexor activation according to the gait cycle. The FES session will consist of 5-minutes stimulation blocks with breaks between blocks (total session time: 30 minutes). For safety reasons, a physical therapist will supervise all the FES intervention sessions.
Study: NCT04975516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Given chemotherapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: Given chemotherapy
Study: NCT06224816

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Traditional mask (TM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received traditional mask during 4 hours, then crossed over to 3D mask.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional mask (TM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received traditional mask during 4 hours, then crossed over to 3D mask.
Study: NCT04252625

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Q-Urol
Description: Q-Urol is an over-the-counter herbal supplement manufactured by Farr Laboratories. It is a combination product composed of quercetin, pollen extract, bromelain, and papain.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo capsule
Study: NCT06149611

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] TQB3616
Description: TQB3616 is a new type of cyclin-dependent kinase (CDK) 4/6 inhibitor.
Study: NCT06060951

Intervention type: DIAGNOSTIC_TEST
Intervention: Estimated intraperitoneal pressure
Description: The following anthropometric measurements are required:~1. Height: measured standing with shoes off~2. Weight: dry weight should be used~3. The distance from the decubitus plane to the mid-axillary line was measured~4. Waist circumference: measured with a tape measure wrapped above the iliac crests around the level of the umbilicus.~The estimated IPP will be assessed using different equations.

Intervention type: DIAGNOSTIC_TEST
Intervention: Estimated intraperitoneal pressure
Description: The following anthropometric measurements are required:~1. Height: measured standing with shoes off~2. Weight: dry weight should be used~3. The distance from the decubitus plane to the mid-axillary line was measured~4. Waist circumference: measured with a tape measure wrapped above the iliac crests around the level of the umbilicus.~The estimated IPP will be assessed using different equations.
Study: NCT04975516

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiation Therapy
Description: Undergo SBRT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT
Study: NCT05652920

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ori-C101
Description: Hepatic arterial infusion
Study: NCT04975516

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood collection

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo blood collection

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT06219746

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PSMA-imaging
Description: Subjects undergo additional imaging i.e. PSMA/SPECT/CT and PSMA/PET/CT
Study: NCT06308380

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Specific protocol of rehabilitation exercise
Description: Specific protocol of rehabilitation exercise

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Specific protocol of rehabilitation exercise
Description: Specific protocol of rehabilitation exercise

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Short gastrocnemius surgery.
Description: During surgery, a partial release of the gastrocnemius muscle tendon is performed to relieve tension and allow greater range of motion. This procedure is typically performed on an outpatient basis and under local or regional anesthesia, which allows for a quicker recovery compared to more invasive surgeries.