TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05627414

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab Vedotin
Description: 2.5mg/kg，IV，Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 200 mg，IV，Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-1
Description: 40\~60mg / m2, bid, d1-14, repeated every 3 weeks.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraperitoneal chemotherapy with paclitaxel
Description: Paclitaxel (PTX) was used with a dose of 60mg / m2, Q3W. （Only for patients with peritoneal metastases）
Study: NCT05479253

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Artificial intelligence assistant system
Description: The artificial intelligence assistant system can automatically capture images, prompt abnormal lesions and the parts covered by the examination (the stomach is divided into 26 parts).
Study: NCT05113160

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conversation Treatment for Aphasia
Description: Conversation treatment is a theoretically motivated approach in which a speech language pathologist facilitates discourse about topics of interest to the client using individualized, multi-modal supports. Treatment occurs either in groups of 6-8 people with aphasia or 2 people with aphasia. Individual communication goals are targeted for each group member within the context of naturalistic conversations.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conversation Treatment for Aphasia
Description: Conversation treatment is a theoretically motivated approach in which a speech language pathologist facilitates discourse about topics of interest to the client using individualized, multi-modal supports. Treatment occurs either in groups of 6-8 people with aphasia or 2 people with aphasia. Individual communication goals are targeted for each group member within the context of naturalistic conversations.
Study: NCT04244630

Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: Antioxidants
Description: Over-the-counter anti-oxidants, namely vitamin E, NAc cysteine, L-cystine, Nicotinamide and Taurursodiol at defined doses
Study: NCT05494021

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole-process management software
Description: Enrolled participants will managed by a pre-designed software. The software would provide helpful assistance, such as lung cancer education, decision-making, assisting in making and attending LCS LDCT appointments, arranging follow-up when needed, tobacco cessation support for smokers, treatment assistance if diagnosed as lung cancer.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LDCT detection
Description: LDCT were performed in both arm. The abnormal nodules were defined as noncalcified nodules (NCN) larger than 5 mm

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LDCT detection
Description: LDCT were performed in both arm. The abnormal nodules were defined as noncalcified nodules (NCN) larger than 5 mm
Study: NCT06038240

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Savoring Meditation
Description: Participants will learn about pain neuroscience and will learn/practice a positive emotion generative practice (Savoring Meditation).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Pain Self-Management and Education
Description: Participants will learn about the biopsychosocial drivers of chronic pain.
Study: NCT04824820

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vibrator
Description: Clitoral stimulation
Study: NCT06273007

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PartoMa intervention(Locally achievable intrapartum care guideline), in house LDHF trainings
Description: We will implement PartoMa interventions: seminars, LDHF training, and supportive supervision

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PartoMa intervention(Locally achievable intrapartum care guideline), in house LDHF trainings
Description: We will implement PartoMa interventions: seminars, LDHF training, and supportive supervision
Study: NCT05207995

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous tolerogenic dendritic cells
Description: Autologous tolerogenic dendritic cells treated with Vitamin-D3, co-cultivated with mesenchymal stem cell and primed peptides (MSC-tolDC) injected subcutaneous.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard treatment according to the clinical protocols
Description: Standard treatment of type 1 diabetes mellitus according to the clinical protocols

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard treatment according to the clinical protocols
Description: Standard treatment of type 1 diabetes mellitus according to the clinical protocols
Study: NCT05496179

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prucalopride
Description: Prokinetic

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metoclopramide
Description: Prokinetic
Study: NCT06603688

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: clarithromycin
Description: clarithromycin 500mg, twice daily for 14 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berberine
Description: Berberine 500 mg, twice daily for 14 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Minocycline
Description: Minocycline 100 mg, twice daily for 14 days
Study: NCT06654609

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Insoles for Foot
Description: Assess the condition of foot ulcers in patients, beginning with creating a cast of the affected foot. After the initial rectification, necessary modifications are made to prepare the rough insole. The size and fit of the insole are then carefully checked against the patient's foot. I use local silicone materials, secured with lady socks or stockinette to ensure the insole stays in place and provides durability.
Study: NCT06654206

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Supervised strength exercise sessions: There will be two sessions per week, each lasting 50 minutes. Each session will consist of three distinct parts:~Warm-up: 10 minutes of global strength and aerobic exercises at 60% of estimated VO2max, focusing on the areas that will primarily be worked on during that session.~Strength training: 6 strength exercises targeting the major muscle groups, lasting 30 minutes. The initial load will be set between 40-70% of the estimated 1-RM (assessed in the first session and based on the individual patient). When the participant is able to complete 3 sets of 12 repetitions with the established weight in two consecutive sessions, the weight will be increased by 10%. The exercises will be performed in a circuit format with 30 seconds of rest between exercises and 90 seconds of rest between sets.~Cool-down/stretching: 10 minutes of a combination of breathing exercises and stretching for the major muscle groups.~Promotion of physical activity: Participants

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Supervised strength exercise sessions: There will be two sessions per week, each lasting 50 minutes. Each session will consist of three distinct parts:~Warm-up: 10 minutes of global strength and aerobic exercises at 60% of estimated VO2max, focusing on the areas that will primarily be worked on during that session.~Strength training: 6 strength exercises targeting the major muscle groups, lasting 30 minutes. The initial load will be set between 40-70% of the estimated 1-RM (assessed in the first session and based on the individual patient). When the participant is able to complete 3 sets of 12 repetitions with the established weight in two consecutive sessions, the weight will be increased by 10%. The exercises will be performed in a circuit format with 30 seconds of rest between exercises and 90 seconds of rest between sets.~Cool-down/stretching: 10 minutes of a combination of breathing exercises and stretching for the major muscle groups.~Promotion of physical activity: Participants
Study: NCT06654778

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEEP
Description: Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEEP/RM
Description: Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEEP/RM/RF
Description: Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery
Study: NCT05488444

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Navigator Phone Calls
Description: The patient navigator will call you every week as described above in Study Groups. These phone calls will continue until you begin receiving chemotherapy.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Navigator Phone Calls
Description: The patient navigator will call you every week as described above in Study Groups. These phone calls will continue until you begin receiving chemotherapy.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exit Interview
Description: Participants will be asked to complete an exit interview either in person or by phone

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exit Interview
Description: Participants will be asked to complete an exit interview either in person or by phone
Study: NCT05788770

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FEops HEARTGuide
Description: FEops HEARTGuide added to routine preoperative CT imaging. Results of the computer modelling will be discussed with TAVR implanting team prior to and during the procedure.
Study: NCT06503614

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Durvalumab 1500mg IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Durvalumab 1500mg IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monalizumab
Description: Monalizumab 1500mg IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monalizumab
Description: Monalizumab 1500mg IV
Study: NCT06599281

Intervention type: OTHER
Group type: OTHER
Intervention: Physiotherapy
Description: The physical therapy program was applied for 3 months, 6 days a week, 2 sessions per day, and an average session duration of 45 minutes. Each neurodevelopmental exercise and proprioceptive exercise was applied for 10 minutes, and stretching exercises were applied for 45 seconds and 3 repetitions. The exercises included functional rotation, sitting with or without arm support, crawling, kneeling, half kneeling, standing up by holding on, and sequencing exercises. Stretching exercises were mostly positional stretches aimed at lateral flexion of the spine.
Study: NCT06594562

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Telementored eFAST
Description: Ultrasound examination guided in real-time by a remote expert for detecting free fluid.
Study: NCT06595134

Intervention type: OTHER
Intervention: Non Interventional
Description: Screening (Day -7 to Day -1) Visit 1 (Day 0) Visit 2 (Month 3 +/- 7 days) Visit 3 (Month 6 +/- 7 days) Visit 4 (Month 12 +/- 7 days) Visit 5 (Month 24 +/- 7 days) Visit 6 (Month 60 +/- 30 days; end of study)

Intervention type: OTHER
Intervention: Non Interventional
Description: Screening (Day -7 to Day -1) Visit 1 (Day 0) Visit 2 (Month 3 +/- 7 days) Visit 3 (Month 6 +/- 7 days) Visit 4 (Month 12 +/- 7 days) Visit 5 (Month 24 +/- 7 days) Visit 6 (Month 60 +/- 30 days; end of study)
Study: NCT06248996

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hyperfractionated radiotherpy
Description: 83.0 Gy in 68 fractions, 1.22 Gy per fraction, two daily fractions, five days per week to the primary tumour volume (GTVT_83.0). To the primary tumour with an added margin (PTVT_74.8) and to neck node metastases (PTVN_74.8) the prescribed dose will be 74.8 Gy in 68 fractions, 1.10 Gy per fraction twice daily. To elective neck nodes (PTV 54.4) the prescribed dose will be 54.4 Gy in 68 fractions, 0.80 Gy per fraction twice daily.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: 68.0 Gy in 34 fractions, 2.00 Gy per fraction per day, five or six days per week to tumour volumes and 54.4 Gy in 34 fractions, 1.60 Gy per fraction to elective neck nodes.
Study: NCT06490354

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lightback group
Description: Use of the patented Lightback device to relax the gluteal musculature and prevent hamstring injuries.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Conventional treatment to relax the gluteal musculature and prevent hamstring injuries.
Study: NCT05106426

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Caregivers- Healthy children
Description: The HC2 intervention is an obesity prevention program that provides nutrition and healthy activities programs administered weekly via Zoom or in-person.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Jump Start
Description: The Jump Start intervention is a behavioral health and safety program that provides behavior management and safety programs administered weekly via Zoom or in-person.
Study: NCT06440434

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Time of night shift
Description: Early vs. late night split night shift

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Time of night shift
Description: Early vs. late night split night shift
Study: NCT06109636

Intervention type: OTHER
Intervention: Pentacam, Corvis ST and Casia2
Description: scleral and ciliary muscle thickness were obtained by Casia2, biomechanical parameters were obtained by Pentacam and Corvis ST
Study: NCT04961151

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal therapeutic warming w/ esophageal d/c
Description: In order to evaluate the ability to reliably raise patient temperature to a target of 39.0°C, patients will be warmed with forced air warming, surface conductive warming, and esophageal core warming. After 4 hours at target temperature, esophageal warming will be discontinued.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal therapeutic warming w/ conductive d/c
Description: In order to evaluate the ability to reliably raise patient temperature to a target of 39.0°C, patients will be warmed with forced air warming, surface conductive warming, and esophageal core warming. After 4 hours at target temperature, conductive warming will be discontinued.
Study: NCT05360173

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: acupressure
Description: The researcher use thumb and put about 3 kilogram on four acupoints where locating on the patient's arm and leg.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: sham acupressure
Description: The researcher use thumb and put about 3 kilogram on four acupoints where locating at about 3 cm next to the acupoint on the patient's arm and leg.
Study: NCT05349851

Intervention type: OTHER
Intervention: Follow-up with blood and urine analysis
Description: The patients will receive the preparation standards according to the usual clinical practice of each center. On the day of the colonoscopy, patient will be informed about this study and the informed consent will be requested to record the study information. Then, an analysis will be carried out. A second visit will be carried out, follow-up at 3-7 days, which will include a clinical interview and an analysis, being the unique intervention that patients receive.
Study: NCT05604820

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Progressive Muscle Relaxation Exercise
Description: Training on progressive muscle relaxation exercises will be given to the experimental group in the chemotherapy unit. Before going to sleep in the evening and during the day, they will be asked to do progressive muscle relaxation exercises in line with the instruction of the video. They will be asked to do the application every day for 8 weeks. At the end of the 2nd week, 4th week, 6th week and 8th week, they will be asked to fill the PUKI again. Only routine care will be applied to the control group and no intervention will be made. At the end of the 2nd week, 4th week, 6th week and 8th week, they will be asked to fill the PUKI again. After the evaluations, information about progressive muscle relaxation exercises will be given.
Study: NCT04404998

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lower Energy Density
Description: Test meal with lower energy density

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lower Energy Density
Description: Test meal with lower energy density

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Higher Energy Density
Description: Test meal with higher energy density

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Higher Energy Density
Description: Test meal with higher energy density

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lower Satiation
Description: Information on lower satiation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lower Satiation
Description: Information on lower satiation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Higher Satiation
Description: Information on higher satiation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Higher Satiation
Description: Information on higher satiation
Study: NCT05895682

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mobiCARE +Pulse (MP100W)
Description: Volunteers were monitored using end-tidal carbon dioxide partial pressure and fraction of inspired oxygen. Each volunteer was placed in a semi-Fowler's position and connected to a breathing circuit to administer the nitrogen-air-carbon dioxide mixtures. A nose clip was applied to prevent breathing of room air. For frequent blood sampling, an arterial cannula was placed in the radial artery of each volunteer. Pulse oximeter probes were simultaneously attached to each volunteer's fingers. Each volunteer was exposed to various levels of induced hypoxia from 70\~100% of SaO2. Each plateau of oxygen saturation was maintained for at least 30 s until stabilization, after which 1 ml of arterial blood was drawn into a heparinized syringe. The study period consisted of two rounds of hypoxia, and the volunteers were maintained on room air between each round. SaO2 measurements using a CO-oximeter were used as a reference for the SpO2 accuracy.
Study: NCT05755295

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: horse therapy
Description: equitherapy and hippotherapy once a week during 16 weeks
Study: NCT06367075

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: injectable solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adriamycin
Description: injectable solution
Study: NCT05929898

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback
Description: fMRI neurofeedback training of sustained midbrain/VTA activation via motivational imagery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback
Description: fMRI neurofeedback training of sustained midbrain/VTA activation via motivational imagery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback
Description: fMRI neurofeedback training of sustained midbrain/VTA activation via motivational imagery.
Study: NCT06226909

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: different types of ultrasound technique
Description: Shear-wave elastography-guided or B-mode ultrasound-guided

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: different types of ultrasound technique
Description: Shear-wave elastography-guided or B-mode ultrasound-guided
Study: NCT04669340

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-learning patient education
Description: The intervention implies patient education through an e-learning program. The program consists of three learning modules covering knowledge of rheumatoid arthritis, medication, examinations, complications and daily living with RA. Module 1 consists of 'need to know' information about disease management, symptoms and medication. Thus, it is mandatory and must be completed before entering module 2 and 3. In module 2 and 3, patients can move around on the basis of their individual needs.~The duration of the full program is approximately two hours, but may vary dependent on the individual user needs. The program may be used as much as needed throughout the study period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard face-to-face patient education
Description: The intervention implies usual care, i.e. face-to-face patient education in a one-hour session with a nurse at the hospital. This form of patient education is based on the patients individual need for information and guidance in relation to rheumatoid arthritis and medication. Thus, aspects of daily life with the disease is discussed at the beginning and forms the conversation. However, as a standard, information of the disease, disease management, symptoms and medication must be discussed with the patient and relatives.
Study: NCT05404399

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Free From Pain Exercise Book
Description: Participants in Group 1 will be provided with the Free From Pain Exercise Book.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy
Description: Participants in Group 2 would be referred to Physiotherapy (usual care)
Study: NCT05788744

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ctDNA
Description: ctDNA guided surveillance
Study: NCT06476210

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BDL regimen
Description: Drug:bedaquiline 100mg tablets~Other Names:~Bdq TMC-207 bedaquiline 400 mg once daily for 2 weeks then 200mg 3 times per week~Drug:delamanid 50mg tablets~Other Names:~Dlm OPC-67683 delamanid 100mg 2 times daily~Drug:linezolid Scored 600mg tablets~Other Names:~Lzd linezolid 600mg once daily