TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06198218

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scapular mobilization
Description: Group A: will be treated with manual scapular mobilization in upward rotation and downward rotation, adduction and abduction of scapula.Sets of 10 repetitions were applied with a rest interval of 30 seconds between set for 20 minutes, activity based scapular mobilization(Codman pendulum exercises, scapular pushups, band wall apart ,wall ball circles and advance study wall pushups) along with conventional physical therapy program(heating,EMS,stretching for tight muscles , strengthening exercises and graduated active exercises) for 25 min

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy program
Description: Group B:will receive conventional physical therapy program including (heating to improve circulation and release muscle tension,EMS,stretching for stiff muscle,weight bearing, strengthening exercises \& graduated active exercises)for 20 min along with activity based scapular mobilization (Codman pendulum exercises,band wall apart,wall ball circles, scapular pushups and advance study wall pushups)for 20 min with 5 min resting interval.
Study: NCT05528328

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CACIPLIQ20®
Description: CACIPLIQ20®

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (saline solution)
Description: Placebo (saline solution) administered in identic al vials
Study: NCT05303337

Intervention type: OTHER
Intervention: Stool sampling
Description: Stool samples will be collected from participants at baseline and W52

Intervention type: OTHER
Intervention: Stool sampling
Description: Stool samples will be collected from participants at baseline and W52

Intervention type: OTHER
Intervention: Blood plasma collection
Description: Blood plasma collection to assess persistent inflammation, immune activation and HIV reservoir at baseline,W24,W52
Study: NCT06293001

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT06321783

Intervention type: OTHER
Group type: OTHER
Intervention: Assessment
Description: Evaluation of cervical proprioception, hand-eye coordination, postural control and endurance of cervical muscles

Intervention type: OTHER
Group type: OTHER
Intervention: Assessment
Description: Evaluation of cervical proprioception, hand-eye coordination, postural control and endurance of cervical muscles
Study: NCT06504823

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Light level
Description: light application

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Light level
Description: light application
Study: NCT04971408

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: passive heat stress
Description: as above

Intervention type: OTHER
Group type: OTHER
Intervention: control
Description: participant engage in activity as usual
Study: NCT05303337

Intervention type: OTHER
Intervention: Blood plasma collection
Description: Blood plasma collection to assess persistent inflammation, immune activation and HIV reservoir at baseline,W24,W52

Intervention type: OTHER
Intervention: Blood plasma collection
Description: Blood plasma collection to assess persistent inflammation, immune activation and HIV reservoir at baseline,W24,W52
Study: NCT05533658

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: VisionPure Dietary Supplement
Description: Subjects will consume two softgels capsules of the Treatment (VisionPure) once daily for 60 days. At Day 0, they will come in for a Comprehensive Eye Exam, a National Eye Institute Visual Functioning Questionnaire, and a series of Cognitive Function Exams. After 60 days, subjects will return and repeat the same questionnaires and exams from Day 0.
Study: NCT05298631

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stabilization exercises
Description: The activation of deep cervical muscle to reduce the activity of surface muscles is known as stabilization exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic exercises
Description: The exercises in which muscle tension remains constant but muscle length changes is known as dynamic exercises
Study: NCT04932278

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Osteopathic manipulative treatment
Description: Osteopathic manipulative treatment (OMT) is hands-on care provided by an osteopathic physician (D.O.). During osteopathic manipulative treatment, an osteopathic physician may move participants' muscles and joints using osteopathic techniques including stretching, gentle pressure and resistance, as well as thrust techniques that apply a quick, therapeutic force of brief duration that travels a short distance.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Routine concussion management with healthcare professionals.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Routine concussion management with healthcare professionals.
Study: NCT05329610

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beta-alanine
Description: Slow-release beta-alanine.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Taste and appearance-matched placebo (tapioca starch).
Study: NCT06461364

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Assessment of cuspal deflection of bulk-fill restorations
Description: To assess the performance of bulk-fill restorations on premolar teeth in class II cavities using some selected FDI criteria, a total sample size of 30 (10 for each group test) will be sufficient to detect: an effect size of 1.22 at a power (1-β error) of 0.8 and using a two-sided hypothesis test and a significance level (α error) 0.05 for data. Two teeth will be added to each group to compensate drop out samples.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Assessment of cuspal deflection of bulk-fill restorations
Description: To assess the performance of bulk-fill restorations on premolar teeth in class II cavities using some selected FDI criteria, a total sample size of 30 (10 for each group test) will be sufficient to detect: an effect size of 1.22 at a power (1-β error) of 0.8 and using a two-sided hypothesis test and a significance level (α error) 0.05 for data. Two teeth will be added to each group to compensate drop out samples.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Assessment of cuspal deflection of bulk-fill restorations
Description: To assess the performance of bulk-fill restorations on premolar teeth in class II cavities using some selected FDI criteria, a total sample size of 30 (10 for each group test) will be sufficient to detect: an effect size of 1.22 at a power (1-β error) of 0.8 and using a two-sided hypothesis test and a significance level (α error) 0.05 for data. Two teeth will be added to each group to compensate drop out samples.
Study: NCT05533658

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will orally consume two softgel capsules of Placebo once daily for 60 days. At Day 0, they will come in for a Comprehensive Eye Exam, a National Eye Institute Visual Functioning Questionnaire, and a series of Cognitive Function Exams. After 60 days, subjects will return and repeat the same questionnaires and exams from Day 0.
Study: NCT06385561

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol
Description: Tramadol is administered orally twice daily in a dosage of 100 mg (daily total of 200 mg)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is administered orally twice daily.
Study: NCT05837507

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telerehabilitation solution (m-Rehab)
Description: Patients in the experimental group will have access to a multimodal digital platform (m-Rehab®). The solution includes a website and an application available on smart phones for the patient and caregivers. Patients and caregivers will have access to educational content about the condition and its treatments, NIV compliance data, digital group educational workshops, secure messaging and video conferencing.~All the professionals forming the patient's circle of care will be able to have access to the solution, after the patient's authorization. The circle of care, in a non-exhaustive way, includes specialist doctors, the general practitioner, the staff of the reference center of the Montpellier University Hospital, the physiotherapist, the speech therapist, the dietician and the psychologist.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual management including NIV.
Description: Usual management including NIV.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual management including NIV.
Description: Usual management including NIV.
Study: NCT05620173

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vedea Amblyopia Therapy (VAT)
Description: Children will use the VAT for 5 days per week, 30 minutes per day. They play VR-games using a VR-headset, which content is optimized for dichoptic training.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vedea Amblyopia Therapy (VAT)
Description: Children will use the VAT for 5 days per week, 30 minutes per day. They play VR-games using a VR-headset, which content is optimized for dichoptic training.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Occlusion therapy
Description: Children are given an eye patch to occlude their dominant eye with for a prescribed number of hours per day. This may typically range anywhere between 2-8 hours per day, depending on the severity of the amblyopia.
Study: NCT06131567

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Implantoplasty
Description: Implantoplasty as surface decontamination method

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implantoplasty
Description: Implantoplasty as surface decontamination method
Study: NCT05484648

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone has been used to generally favorable results in peripheral nerve blocks as adjunct. Several studies have reported prolongation in the duration of ropivacaine, mepivacaine and bupivacaine when used in combination with dexamethasone.~Various mechanisms for the beneficial adjunctive effect of dexamethasone with Local Anesthetics (LA) have been proposed. One theory suggests that the improved analgesia and increased blockade duration is due to its anti-inflammatory properties. It also acts as a local vasoconstrictor and thus may act by reducing LA absorption. Furthermore, it also increases the activity of inhibitory potassium channels on nociceptive C-Fibers.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine is another promising drug being used as a local anaesthetic adjuvant in peripheral nerve blocks. It is an alpha-2 agonist, which has shown to have prolonged duration of postoperative analgesia when given with LA for peripheral nerve blocks with other beneficial effects such as reducing the opioid consumption. Alpha-2-agonists such as dexmedetomidine cause hyperpolarization-activated cation currents which inhibit the transmission of nociceptive fibers.
Study: NCT06060119

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: microneedling
Description: The operative sites will be anaesthetized with 2% lignocaine hydrochloride with adrenaline(1:80,000).Electric microneedling pen device model THAPPINKTM is used. Microneedling is carried out on the isolated site involving one tooth mesially and distally and 1.5mm apical to marginal gingiva each for 30-40 second intermittently. When pin point bleeding observed on the area of gingiva it is irrigated with sterile saline solution. Patient will be instructed to refrain from consuming hot beverage and brushing in that area for one day to avoid mechanical trauma. A total of 4 session of micro needling procedure will be carried out in one subject at 10 days intervals upto 40days

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: microneedling
Description: The operative sites will be anaesthetized with 2% lignocaine hydrochloride with adrenaline(1:80,000).Electric microneedling pen device model THAPPINKTM is used. Microneedling is carried out on the isolated site involving one tooth mesially and distally and 1.5mm apical to marginal gingiva each for 30-40 second intermittently. When pin point bleeding observed on the area of gingiva it is irrigated with sterile saline solution. Patient will be instructed to refrain from consuming hot beverage and brushing in that area for one day to avoid mechanical trauma. A total of 4 session of micro needling procedure will be carried out in one subject at 10 days intervals upto 40days
Study: NCT05493644

Intervention type: OTHER
Intervention: Remedial treatment within 3 months
Description: Remedial therapy was performed within 3 months

Intervention type: OTHER
Intervention: Remedial treatment within 3 to 6 months
Description: Remedial therapy was performed within 3 to 6 months

Intervention type: OTHER
Intervention: Remedial treatment within 6 to 12 months
Description: Remedial therapy was performed within 6 to 12 months

Intervention type: OTHER
Intervention: Remedial treatment after 12 months
Description: Remedial therapy was performed after 12 months
Study: NCT04739137

Intervention type: DIAGNOSTIC_TEST
Intervention: DDiVAT Testing
Description: Participants will self examine his/her distance visual acuity via application in a simulation room of our department with certain predetermined environmental lighting conditions using the same smart devices.

Intervention type: DIAGNOSTIC_TEST
Intervention: Distance visual acuity assessment via ETDRS chart
Description: The distance visual acuity of each participant will be measured with the conventional method via ETDRS chart
Study: NCT06108024

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SM-020 gel 1.0%
Description: SM-020 gel 1.0% will be applied topically. Subjects will be treated with twice daily application to 5 to 10 SKTLs for approximately 28 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle gel
Description: Vehicle gel will be applied topically. Subjects will be treated with twice daily application to 5 to 10 SKTLs for approximately 28 days.
Study: NCT05057936

Intervention type: BIOLOGICAL
Intervention: COVID vaccine
Description: The enrolled patients will received COVID-19 vaccine according to the vaccine protocol in Thailand ie The ChAdox-1 nCOV-19 vaccine (day 1, day 84, 12 weeks duration) or Corona vac 2 doses (day 2, day 21, 3 weeks duration) of the study. All the participants underwent blood drawn for antibody and cellular immunity measurement before the final dose of vaccination, with 7 days before first vaccine dose and eight weeks after the second doses

Intervention type: BIOLOGICAL
Intervention: COVID vaccine
Description: The enrolled patients will received COVID-19 vaccine according to the vaccine protocol in Thailand ie The ChAdox-1 nCOV-19 vaccine (day 1, day 84, 12 weeks duration) or Corona vac 2 doses (day 2, day 21, 3 weeks duration) of the study. All the participants underwent blood drawn for antibody and cellular immunity measurement before the final dose of vaccination, with 7 days before first vaccine dose and eight weeks after the second doses

Intervention type: BIOLOGICAL
Intervention: COVID vaccine
Description: The enrolled patients will received COVID-19 vaccine according to the vaccine protocol in Thailand ie The ChAdox-1 nCOV-19 vaccine (day 1, day 84, 12 weeks duration) or Corona vac 2 doses (day 2, day 21, 3 weeks duration) of the study. All the participants underwent blood drawn for antibody and cellular immunity measurement before the final dose of vaccination, with 7 days before first vaccine dose and eight weeks after the second doses

Intervention type: BIOLOGICAL
Intervention: COVID vaccine
Description: The enrolled patients will received COVID-19 vaccine according to the vaccine protocol in Thailand ie The ChAdox-1 nCOV-19 vaccine (day 1, day 84, 12 weeks duration) or Corona vac 2 doses (day 2, day 21, 3 weeks duration) of the study. All the participants underwent blood drawn for antibody and cellular immunity measurement before the final dose of vaccination, with 7 days before first vaccine dose and eight weeks after the second doses

Intervention type: BIOLOGICAL
Intervention: COVID vaccine
Description: The enrolled patients will received COVID-19 vaccine according to the vaccine protocol in Thailand ie The ChAdox-1 nCOV-19 vaccine (day 1, day 84, 12 weeks duration) or Corona vac 2 doses (day 2, day 21, 3 weeks duration) of the study. All the participants underwent blood drawn for antibody and cellular immunity measurement before the final dose of vaccination, with 7 days before first vaccine dose and eight weeks after the second doses
Study: NCT04521582

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlodipine
Description: The facility-based community health worker will receive protocol-driven training to initiate amlodipine for hypertensive patients. These patients will receive lifestyle counseling by Female Community Health Volunteer through home visits (5 times \[including baseline and end of the study\] in the active municipality and 3 times \[including baseline and end of the study\] in the control municipality).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle counselling
Description: Female Community Health Volunteer will provide lifestyle counseling at the participant's home
Study: NCT05388331

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT05628532

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of the DBLG1 system
Description: During the treatment period, the patient will use the DBLG1 system (consisting of a DBLG1 handset with an embedded software named loop mode, a TERUMO MEDISAFE WITH patch pump and a Dexcom continuous glucose monitoring (CGM) G6). The main function of DBLG1 System is to adjust the insulin delivery at the correct time in order to maintain the patient's blood glucose in the target range and thus minimize both hypoglycaemic events and long-term complications associated with elevated average glycemia.
Study: NCT05923437

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Feeding model group with a chronobiological approach
Description: Breast milk will be given to the newborns in the intervention group for 3 days in line with the feeding model with a chronobiologic approach simultaneously with the provision from the mother, and the newborn will be ensured to receive breast milk in accordance with the day cycle. Within the scope of the study, firstly, mothers and nurses in the NICU will be informed about the study. Mothers will be asked to put the milk mothers express between 06:00-17:59 in the daytime breast milk storage bag and the milk mothers express between 18:00-05:59 in the nighttime breast milk storage bag and bring them to the unit. The brought breast milk will be prepared by the nurses by matching day and night milk according to the dates, with the first milk brought in priority, and the newborns will be fed by using the time of day factor (cycle so that the milk collected during the day will be given during the day and the milk expressed at night will be given at night).
Study: NCT04521582

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle counselling
Description: Female Community Health Volunteer will provide lifestyle counseling at the participant's home
Study: NCT05632328

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN1423
Description: via IV, dosage per protocol, once every 2 weeks for up to 8 weeks
Study: NCT04972695

Intervention type: DIAGNOSTIC_TEST
Intervention: Fundus Photographs (retinographies)
Description: Fundus photographs under mydriasis

Intervention type: DIAGNOSTIC_TEST
Intervention: Fundus Photographs (retinographies)
Description: Fundus photographs under mydriasis
Study: NCT06505889

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Local anesthesia methods
Description: Local pain control method before arterial blood sampling procedure

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Local anesthesia methods
Description: Local pain control method before arterial blood sampling procedure
Study: NCT06266169

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: making artificial intelligence based decisions of gamete, embryo and endometrial potential
Description: The method of Raman spectroscopy is based on the registration of inelastic scattering of photons. Each compound has its own spectral pattern when using a certain type of monochromatic radiation (laser). With this method, it is possible to obtain metabolic fingerprints from the objects being studied. Luminescent spectroscopy is a type of spectroscopy used to register emission from objects that occurred after absorbing the exciting (primary) radiation. Spectrophotometry is the detection of radiation in the visible area of the spectrum. Raman spectroscopy is used for the spent medium and semen to build artificial intelligence model and make prognosis of function for each object. For endometrium, luminescent spectroscopy and spectrophotometry are used to build the model and test its clinical relevance
Study: NCT04614064

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure to London Underground ambient particulate matter
Description: Exposure to particulate matter on the London Underground

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure to London Underground ambient particulate matter
Description: Exposure to particulate matter on the London Underground

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure to London air ambient particulate matter
Description: Exposure to ambient particulate matter on the London Overground (as a proxy as a proxy for a clean air London area while maintaining other aspects of a train journey)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure to London air ambient particulate matter
Description: Exposure to ambient particulate matter on the London Overground (as a proxy as a proxy for a clean air London area while maintaining other aspects of a train journey)
Study: NCT06282107

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: BiSAAE
Description: SAAE is a catheter-based percutaneous transluminal procedure which selectively injects ethanol into bilateral adrenal artery to ablate part of the adrenal gland for suppression of excessive aldosterone and catecholamines

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: traditional triple antihypertensive treatment
Description: traditional triple antihypertensive treatment
Study: NCT05371691

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Myofunctional appliance
Description: Myifunctional appliance will be used for growing patients who have Cl.II div.1 malocclusion, two types of appliances are involved myobrace and twin=block appliance

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Myofunctional appliance
Description: Myifunctional appliance will be used for growing patients who have Cl.II div.1 malocclusion, two types of appliances are involved myobrace and twin=block appliance