TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06294275

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LP-001 Dose 6 (Single)
Description: A single dose of LP-001 (Dose 6) was administered subcutaneously.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Single)
Description: A single dose of placebo was administered subcutaneously.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LP-001 Dose 7 (Multiple)
Description: LP-001 (Dose 7) was administered multiple times subcutaneously.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LP-001 Dose 8 (Multiple)
Description: LP-001 (Dose 8) was administered multiple times subcutaneously.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Multiple)
Description: Placebo was administered multiple times subcutaneously.
Study: NCT05228054

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: laser procedure
Description: In modified litothomy position patients with hemorrhoidal deasease will be treated with transcutaneous laser 1940nm 3watt in impulse regimen
Study: NCT04147871

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ADV7103
Description: Each dose of ADV7103 contains a fixed ratio of 1/3 of ADV7103-CK (potassium citrate) and 2/3 of ADV7103-BK (potassium bicarbonate) based on the mass of active substances.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ADV7103
Description: Each dose of ADV7103 contains a fixed ratio of 1/3 of ADV7103-CK (potassium citrate) and 2/3 of ADV7103-BK (potassium bicarbonate) based on the mass of active substances.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ADV7103
Description: Each dose of ADV7103 contains a fixed ratio of 1/3 of ADV7103-CK (potassium citrate) and 2/3 of ADV7103-BK (potassium bicarbonate) based on the mass of active substances.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is a combination of 2 mm green coated lactose granules and 2 mm white coated lactose granules.~Each dose of placebo contains a fixed ratio of 1/3 of green granules and 2/3 of white granules.
Study: NCT05613816

Intervention type: PROCEDURE
Intervention: Senhance Surgical System
Description: 100 patients affected by uterine diseases with indication for hysterectomy undergo treatment with robotically assisted laparoscopic procedures using the Senhance Surgical System
Study: NCT05437757

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical implantation of the PCL Breast scaffold with autologous fat grafting
Description: Single shot of prophylactic perioperative antibiotics is given to the patient. A suitable incision is made to provide access followed by mobilisation of the breast gland.If present, the silicone implant is removed and capsulectomy performed. The implant pocket shall be rinsed with saline or antiseptic and a surgical drain shall be placed in the pocket at the discretion of the PI. The PCL Breast scaffold shall be inserted into the pocket and fixed using 2 to 4 sutures. The incision is closed. Liposuction is performed from another area of the body and lipofilling is performed within the breast scaffold. Sterile bandaging is applied and a daily wound revision is performed whilst an inpatient. A prophylactic antibiotic shall be administered to the patient.The patients shall be hospitalized overnight for clinical observation.
Study: NCT06432465

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active tDCS
Description: The anode will be placed over the right DLPFC (F4 on the EEG 10-20 system) and the cathode over the left DLPFC65 (F3) using 25cm2 sponges at an intensity of 2mA. Stimulation will be delivered for 20 minutes via two saline-soaked surface sponge electrodes and a battery-driven, constant current stimulator (NeuroConn DC Stimulator Plus).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tDCS
Description: Same device and procedures as active tDCS with the exception that the device includes a study mode, in which subject-specific codes are entered to deliver active or sham stimulation, keeping the administrator blinded. Sham stimulation will use a method in which stimulation will be ramped up and back down over a 30-second period at the beginning and end of sham tDCS.
Study: NCT04650490

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: Timing of stereotactic radiosurgery relative to immunotherapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: Timing of stereotactic radiosurgery relative to immunotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunotherapy
Description: Physician's choice of immunotherapy per standard of care

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunotherapy
Description: Physician's choice of immunotherapy per standard of care
Study: NCT05986032

Intervention type: DIAGNOSTIC_TEST
Intervention: Respiratory Oscillometry
Description: Measurement of respiratory system reactance by respiratory oscillometry
Study: NCT05752500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Intervention for Physical Activity
Description: Interventionist will use cognitive and behavioral techniques to help the participant increase facilitators and decrease barriers to physical activity, particularly barriers such as lack of motivation, depression, and chronic pain. Meetings will occur every other week for 4 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Intervention for Physical Activity
Description: Interventionist will use cognitive and behavioral techniques to help the participant increase facilitators and decrease barriers to physical activity, particularly barriers such as lack of motivation, depression, and chronic pain. Meetings will occur every other week for 4 months.
Study: NCT05752500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Intervention for Physical Activity
Description: Interventionist will use cognitive and behavioral techniques to help the participant increase facilitators and decrease barriers to physical activity, particularly barriers such as lack of motivation, depression, and chronic pain. Meetings will occur every other week for 4 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Intervention for Physical Activity
Description: Interventionist will use cognitive and behavioral techniques to help the participant increase facilitators and decrease barriers to physical activity, particularly barriers such as lack of motivation, depression, and chronic pain. Meetings will occur every other week for 4 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Support for Physical Activity
Description: This component will leverage the social functionality of the Fitbit app, promoting social support and friendly competition via a moderated Facebook group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Support for Physical Activity
Description: This component will leverage the social functionality of the Fitbit app, promoting social support and friendly competition via a moderated Facebook group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Support for Physical Activity
Description: This component will leverage the social functionality of the Fitbit app, promoting social support and friendly competition via a moderated Facebook group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Support for Physical Activity
Description: This component will leverage the social functionality of the Fitbit app, promoting social support and friendly competition via a moderated Facebook group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Coaching
Description: The PA coach will meet with the participant to set goals for physical activity (steps) and encourage self-monitoring. Meetings will occur every other week for 4 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Coaching
Description: The PA coach will meet with the participant to set goals for physical activity (steps) and encourage self-monitoring. Meetings will occur every other week for 4 months.
Study: NCT05228054

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: sclerotherapy
Description: In modified litothomy position patients with hemorrhoidal deasease will be treated with sclerotherapy with Aethoxysklerol
Study: NCT05459259

Intervention type: OTHER
Intervention: Interviews and Delphi Survey
Description: no intervention delivered
Study: NCT05752500

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Coaching
Description: The PA coach will meet with the participant to set goals for physical activity (steps) and encourage self-monitoring. Meetings will occur every other week for 4 months.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Coaching
Description: The PA coach will meet with the participant to set goals for physical activity (steps) and encourage self-monitoring. Meetings will occur every other week for 4 months.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.
Study: NCT05732038

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Minds Program (HMP)
Description: Participants assigned to the HMP group will be asked to complete a minimum of 10 minutes per day of meditation for 12 weeks. For the first four weeks, participants will listen to prescribed meditations that will teach them the foundations of mindfulness. During weeks 5-12, participants will have full access to the HMP meditation library.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wellness App (WA)
Description: Participants in the WA group will listen to a minimum of 10 minutes per day of a caregiver specific educational podcast (including topics such as Caring for the Caregiver or Folate and Preventing Alzheimer's) delivered via a mobile app for the 12 weeks. The app contains one podcast per day for twelve weeks.
Study: NCT05857748

Intervention type: DRUG
Intervention: lifitegrast
Description: patient newly started on medication will be followed for 6 months
Study: NCT04742270

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SIMEOX+ respiratory physiotherapy telecare
Description: Every 10 days, the patient's expert physiotherapist will contact the patient by video-transmission or telephone call for motivational reinforcement and technical support in the use of the device.~During these phone calls, a quick 3-question questionnaire will be administered to the patient to monitor events of hemoptysis, chest pain and clinical symptoms of gastroesophageal reflux disease: pyrosis.If patients report this type of event, the physiotherapist will inform the patient's physician for management at his/her discretion.~The expert physiotherapist will also conduct this sessions in order to increase the patient's motivation and compliance to the device. In order to do this, he will identify (in collaboration with the patient), the patient's difficulties and obstacles and he will try to find solutions with him.
Study: NCT05202769

Intervention type: OTHER
Intervention: Video filming
Description: Video clips taken using RGB and thermal imaging cameras under varying conditions of lighting, movement and procedures taking place.

Intervention type: OTHER
Intervention: Video filming
Description: Video clips taken using RGB and thermal imaging cameras under varying conditions of lighting, movement and procedures taking place.
Study: NCT05675241

Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical examination of a dental implant
Description: Clinical examination includes bleeding on probing, pocket depth, gingival biotype, suppuration, gingival index

Intervention type: DIAGNOSTIC_TEST
Intervention: Radiological Examination
Description: A standardized periapical radiograph in parallax technique will be taken.

Intervention type: DIAGNOSTIC_TEST
Intervention: Peri-implant crevicular fluid sample collection
Description: A sample of the peri-implant crevicular fluid will be collected using paper strip for 60 seconds. The sample of the fluid will be a resultant of inserting six different strips at the same time in six sites of the implant including mesiobuccal, midbuccal, distobuccal, distopalatal/distolingual, midpalatal/midlingual, mesiopalatal/mesiolingual sites of the implant.
Study: NCT05338021

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intrawound administration of vancomycin after closure of the arthrotomy
Description: After closure of the arthrotomy, 1 g of vancomycin powder suspended in 30ml of normal saline was injected directly into the joint with an 18-gauge needle.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intrawound administration of vancomycin after closure of the arthrotomy
Description: After closure of the arthrotomy, 1 g of vancomycin powder suspended in 30ml of normal saline was injected directly into the joint with an 18-gauge needle.
Study: NCT04476628

Intervention type: DRUG
Group type: OTHER
Intervention: Budesonide
Description: Budesonide is a corticosteroid that is commonly used intranasally to treat CRS.

Intervention type: DRUG
Group type: OTHER
Intervention: Budesonide
Description: Budesonide is a corticosteroid that is commonly used intranasally to treat CRS.

Intervention type: DEVICE
Group type: OTHER
Intervention: Mucosal Atomization Device
Description: MAD is a device used as an addition to a syringe to atomize medication to increase area of distribution. It is used to administer budesonide within the nasal passages and sinuses to administer medication for CRS.

Intervention type: DEVICE
Group type: OTHER
Intervention: Mucosal Atomization Device
Description: MAD is a device used as an addition to a syringe to atomize medication to increase area of distribution. It is used to administer budesonide within the nasal passages and sinuses to administer medication for CRS.

Intervention type: DEVICE
Group type: OTHER
Intervention: NeilMed squeeze bottle for Impregnated Nasal Saline Irrigation
Description: INSI is delivered using a NeilMed squeeze bottle. It is used to administer budesonide within the nasal passages and sinuses to administer medication for CRS.

Intervention type: DEVICE
Group type: OTHER
Intervention: NeilMed squeeze bottle for Impregnated Nasal Saline Irrigation
Description: INSI is delivered using a NeilMed squeeze bottle. It is used to administer budesonide within the nasal passages and sinuses to administer medication for CRS.
Study: NCT05009836

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Savolitinib
Description: Subjects will receive Savolitinib orally once per day (QD) + Osimertinib orally QD,21day cycles (every 3 weeks) until disease progression, death, adverse event (AE) leading to discontinuation or withdrawal of consent.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will receive placebo orally once per day (QD) + Osimertinib orally QD,21day cycles (every 3 weeks) until disease progression, death, adverse
Study: NCT04961905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVP-2002-R1+NVP-2002-R2
Description: NVP-2002-R1 1 tablet, once daily and NVP-2002-R2 1 tablet, once daily
Study: NCT05231174

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A self-evlaution tool based on Large Language Model
Description: Following the baseline assessment, participants will be guided to use a self-evaluation tool independently to assess their risk of diabetic retinopathy (DR). This tool is a fusion of a conversational AI system based on LLM and an existing logistic diagnostic model.~The AI system is designed to collect clinical variables, including age, duration of diabetes, Body Mass Index (BMI), and insulin usage. Additionally, clinical test data such as mean arterial pressure, HbA1c, serum creatinine, and microalbuminuria will be extracted from a local dataset using the patient's name and ID. Once collected, these data will be transmitted to a server-based diagnostic model for further analysis to determine the presence of DR.
Study: NCT04742426

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: WHO recommended PPE
Description: Uses polycarbonate safety spectacles, fluid-resistant (Type IIR) surgical mask and disposable surgical gown. No head or foot cover.
Study: NCT04961905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVP-2002-R1+NVP-2002-R2
Description: NVP-2002-R1 1 tablet, once daily and NVP-2002-R2 1 tablet, once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVP-2002
Description: NVP-2002 is a combination of NVP-2002-R1 and NVP-2002_R2 NVP-2002, 1 tablet, once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVP-2002
Description: NVP-2002 is a combination of NVP-2002-R1 and NVP-2002_R2 NVP-2002, 1 tablet, once daily
Study: NCT05568329

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hearing Aid Program
Description: Each subject will listen to recordings of music processed by seven different hearing aid brands set to the default Speech in Quiet program and the default Music program. Recordings (hearing aid brand x program x music sample) will be randomized from trial to trial.
Study: NCT04742426

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Super-safe setup
Description: Uses surgical cap, FFP3 respirator covered by surgical mask, face shield, whole-body suit (Tyvec), 3 pairs of gloves typed to suit sleeves and disposable foot cover.
Study: NCT06258135

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Galacto-oligosaccharide
Description: Single 7g dose daily for 28 days

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Single 7g dose daily for 28 days
Study: NCT06170801

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kiesler Circle Training (KCT)
Description: Kiesler Circle Training is a transdiagnostic modular group treatment, which comprises a baseline module and four additional independent modules (nonverbal communication, verbal communication, conflict training and empathy and corrective interpersonal experiences). KCT is based on a heuristic model to explain and anticipate interactions developed by Donald Kiesler and other representatives of the interpersonal theory. The circumplex model arranges the variety of interpersonal behaviors in terms of a circular continuum allocated on two orthogonal axes: The vertical axis addresses interpersonal control (agency), the horizontal axis addresses interpersonal communion. The model further allows illustrating complementary action tendencies to anticipate other's reactions and to guide own behavior to achieve interpersonal goals. KCT is designed for increasing the awareness of such interpersonal action tendencies and for improving interpersonal behavioral flexibility.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy (CBT)
Description: Cognitive Behavioral Therapy is based on the interrelationships of thoughts, actions and feelings. Presumably, individual CBT will address intrapersonal therapeutic foci such as behavioral activation, identification of dysfunctional thoughts, overcoming fears by exposure, etc. Individual CBT may also include interpersonal functioning as therapeutic foci. Disorder-specific treatment manuals are available for all diagnoses included in the study. Of note, state-of-the-art CBT does not necessarily mean, that individual CBT-sessions strictly adhere to a manual. However, because both study sites are CBT training institutes, which guarantee supervision at least every four hours, it can be estimated that state-of-the-art CBT is realized.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy (CBT)
Description: Cognitive Behavioral Therapy is based on the interrelationships of thoughts, actions and feelings. Presumably, individual CBT will address intrapersonal therapeutic foci such as behavioral activation, identification of dysfunctional thoughts, overcoming fears by exposure, etc. Individual CBT may also include interpersonal functioning as therapeutic foci. Disorder-specific treatment manuals are available for all diagnoses included in the study. Of note, state-of-the-art CBT does not necessarily mean, that individual CBT-sessions strictly adhere to a manual. However, because both study sites are CBT training institutes, which guarantee supervision at least every four hours, it can be estimated that state-of-the-art CBT is realized.
Study: NCT02590523

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin
Description: Intracameral vancomycin injection during cataract surgery

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxifloxacin
Description: Intracameral moxifloxacin injection during cataract surgery

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intracameral placebo injection with BSS during cataract surgery