TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05828264

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Quantum touch
Description: this group by the nurse who is included in the study and who has a practice certificate before vascular access is established. In this process, the treatment process of the patient will continue and will not create an obstacle. While the child is in a comfortable position (lying or sitting position) during the application, the child's back/shoulder/head will be touched by the practitioner and guantum touch energy will be applied. Then, vascular access will be performed by the nurse included in the study. The child will be asked to rate the level of pain during the procedure with 'FPS-R', the level of fear with 'CDS', and the level of anxiety with 'ÇAS-D'.
Study: NCT04841629

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PreBioGyn Gel
Description: Cellulose-based prebiotic gel developed to optimize vaginal health and reduce the risk of cervical cancer in women.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Trimosan Gel
Description: Carbomer-based gel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: RepHresh Gel
Description: Carbomer-based gel
Study: NCT05725798

Intervention type: DRUG
Intervention: Sitagliptin
Description: Group 1 who regularly takes Sitagliptin due to diabetes mellitus type 2 continues the treatment perioperatively. Group 2 and group 3 do not take Sitagliptin.
Study: NCT05603624

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cervical examination to assess labor
Description: Patients were randomized to receive cervical examinations to assess progression in labor with either sterile or clean gloves.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Cervical examination to assess labor
Description: Patients were randomized to receive cervical examinations to assess progression in labor with either sterile or clean gloves.
Study: NCT06002282

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tailored messages
Description: Messages will be individually tailored to parents' responses to a baseline survey (child gender, vaccination status) and real-time responses to interactive prompts about vaccine hesitancy determinants with links to additional information (e.g., CDC, NJ Department of Health) and community resources to overcome barriers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard messages
Description: Generic reminder/recall HPV vaccination messages.
Study: NCT04718987

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Low dose rate (LDR) brachytherapy
Description: Low dose rate (LDR) brachytherapy is a type of radiation treatment where doctor places the radioactive implants (seeds) inside patient's prostate gland and these seeds emits low dose radiation over a certain period of time. During low-dose-rate brachytherapy, a continuous low dose of radiation is released over time -from several hours to several days.
Study: NCT04895787

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gait + rest
Description: Following skill-based gait training, the participants will sit and rest on a chair.
Study: NCT06039891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nimotuzumab、Tislelizumab
Description: Subjects will receive Nimotuzumab 400 mg/time, intravenous injection, qw; Tislelizumab 200 mg/time, q3w until disease progression, intolerable toxicity, or 24 months of medication
Study: NCT05416229

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin-assisted therapy

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Placebo-assisted therapy
Study: NCT06192446

Intervention type: DRUG
Intervention: Survey using a questionnaire.
Description: An observational study conducted in a cross-sectional manner using a questionnaire.
Study: NCT04877548

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fermented orange flour
Description: Volunteers will have to consume a standardized breakfast including fermented orange flour and presenting 50g of available carbohydrates

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fermented grape flour
Description: Volunteers will have to consume a standardized breakfast including fermented grape flour and presenting 50g of available carbohydrates

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Volunteers will have to consume a standardized breakfast without fermented flour but also presenting 50g of available carbohydrates
Study: NCT06257979

Intervention type: OTHER
Group type: OTHER
Intervention: This study is with minimal risk and minimal constraints due to the addition of questionnaires
Description: In this study, the specific procedures compared to routine care are :~* Considering the addition of questionnaires, this study will be prospective. Due to the use of bacteriological samples, it is considered as a minimal-risk research.~* The research procedure involves a bacteriological analysis of operative elements (sutures placed during the first intervention, the product of tendon debridement, and the subacromial bursa (cleaning product)) used during the re-intervention. These usually discarded operative samples are collected for bacteriological analysis.~* Antibiotic treatment cannot be prescribed immediately after the surgery and during the first month following this re-intervention (time for biofilm formation). As per the protocol, even a positive sample should not lead to the initiation of systematic antibiotic therapy. In the case of identification of a pathogenic microorganism, antibiotic therapy will be prescribed, leading to discontinuation of the study.

Intervention type: OTHER
Group type: OTHER
Intervention: This study is with minimal risk and minimal constraints due to the addition of questionnaires
Description: In this study, the specific procedures compared to routine care are :~* Considering the addition of questionnaires, this study will be prospective. Due to the use of bacteriological samples, it is considered as a minimal-risk research.~* The research procedure involves a bacteriological analysis of operative elements (sutures placed during the first intervention, the product of tendon debridement, and the subacromial bursa (cleaning product)) used during the re-intervention. These usually discarded operative samples are collected for bacteriological analysis.~* Antibiotic treatment cannot be prescribed immediately after the surgery and during the first month following this re-intervention (time for biofilm formation). As per the protocol, even a positive sample should not lead to the initiation of systematic antibiotic therapy. In the case of identification of a pathogenic microorganism, antibiotic therapy will be prescribed, leading to discontinuation of the study.
Study: NCT06023498

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy and Exercise
Description: The 20-minute manual therapy procedures will include:~* Distraction-manipulation: manually assisted segmental lumbar traction manipulation using a specialized treatment table~* Neural mobilization: rhythmic stretches of the sciatic and femoral nerves75~* Hip, sacroiliac and lumbar facet mobilizations to improve joint mobility~* Soft tissue mobilization of lumbopelvic and lower extremity muscles using manual pressure over taut bands/myofascial trigger points and post-isometric (contract-relax) stretching techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy and Exercise
Description: The 20-minute manual therapy procedures will include:~* Distraction-manipulation: manually assisted segmental lumbar traction manipulation using a specialized treatment table~* Neural mobilization: rhythmic stretches of the sciatic and femoral nerves75~* Hip, sacroiliac and lumbar facet mobilizations to improve joint mobility~* Soft tissue mobilization of lumbopelvic and lower extremity muscles using manual pressure over taut bands/myofascial trigger points and post-isometric (contract-relax) stretching techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy and Exercise
Description: The 20-minute manual therapy procedures will include:~* Distraction-manipulation: manually assisted segmental lumbar traction manipulation using a specialized treatment table~* Neural mobilization: rhythmic stretches of the sciatic and femoral nerves75~* Hip, sacroiliac and lumbar facet mobilizations to improve joint mobility~* Soft tissue mobilization of lumbopelvic and lower extremity muscles using manual pressure over taut bands/myofascial trigger points and post-isometric (contract-relax) stretching techniques.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intramuscular Electroacupuncture
Description: As described previously
Study: NCT06463262

Intervention type: DIAGNOSTIC_TEST
Intervention: ctDNA
Description: the effects of neoadjuvant RT, in the form of either proton therapy or SBRT, on the ctDNA
Study: NCT05303441

Intervention type: PROCEDURE
Intervention: percutaneous coronary intervention
Description: conventional coronary angiography
Study: NCT06066671

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: GCO (Experimental copaiba oil resin gel)
Description: Prior to bleaching treatment with 35% hydrogen peroxide, the dental elements of the GCO will receive the application of the experimental desensitizing gel on the buccal surfaces of the central incisors, lateral incisors, canines and upper and lower premolars, with a rubber cup in an active way, for 10 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GCO (Experimental copaiba oil resin gel)
Description: Prior to bleaching treatment with 35% hydrogen peroxide, the dental elements of the GCO will receive the application of the experimental desensitizing gel on the buccal surfaces of the central incisors, lateral incisors, canines and upper and lower premolars, with a rubber cup in an active way, for 10 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: GCO (Experimental copaiba oil resin gel)
Description: Prior to bleaching treatment with 35% hydrogen peroxide, the dental elements of the GCO will receive the application of the experimental desensitizing gel on the buccal surfaces of the central incisors, lateral incisors, canines and upper and lower premolars, with a rubber cup in an active way, for 10 minutes.
Study: NCT05842720

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: un-sedated colonoscopies
Description: un-sedated colonoscopies in high risk patients with ASA\>=3

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: un-sedated colonoscopies
Description: un-sedated colonoscopies in high risk patients with ASA\>=3
Study: NCT05975112

Intervention type: DIAGNOSTIC_TEST
Intervention: Coagulation tests (TEG, Levels of F1, F2, hs-D-dimer, Plasminogen, PAI 1+2), SpHb before discharge
Description: Coagulation tests named earlier as well as SpHb

Intervention type: DIAGNOSTIC_TEST
Intervention: Coagulation tests (TEG, Levels of F1, F2, hs-D-dimer, Plasminogen, PAI 1+2), SpHb before discharge
Description: Coagulation tests named earlier as well as SpHb
Study: NCT05958381

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation
Description: Transcranial direct current stimulation will be delivered via a Neuroelectrics Starstim tES. Stimulation will consist of 1 milliamp stimulation, with anodal stimulation delivered at electrode Fz (International 10/10 System for electroencephalography electrode placement) and electrodes F7, FP1, FP2, and F8 as returns. All electrodes are 1 cm diameter Ag/AgCl electrodes and make contact with the scalp via connective gel. Stimulation will linearly ramp up from 0 milliamps to 1 milliamp over 60 seconds, then remain at 1 milliamp of stimulation over 20 minutes, and finally ramping down at to 0 milliamps over 60 seconds.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial direct current stimulation
Description: Sham transcranial direct current stimulation will be delivered via a Neuroelectrics Starstim tES. The sham setup will consist of anodal electrode Fz (International 10/10 System for electroencephalography electrode placement) and electrodes F7, FP1, FP2, and F8 as returns. All electrodes are 1 cm diameter Ag/AgCl electrodes and make contact with the scalp via connective gel. Stimulation will linearly ramp up from 0 milliamps to 1 milliamp over 60 seconds, ramp down to 0 milliamps over 60 seconds and then be left off for 20 minutes.
Study: NCT05646238

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: psychoeducation
Description: Students assigned to the experimental group will be divided into groups of 6-9. 3 psychoeducation sessions will be held with each group once a week for a total of 3 weeks. Group sessions are estimated to last between 60-75 minutes. Psychoeducational content based on Leventhal's Self-Regulation Model was prepared. In the first stage, cognitive bases of dysmenorrhea, in the second stage, strategies to cope with dysmenorrhea, and in the third stage, the effectiveness of coping strategies in dysmenorrhea will be discussed. In the second stage, the participants will be taught the progressive muscle relaxation exercise, which is among the strategies to cope with dysmenorrhea. Sessions will be held online.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: training
Description: The control group will be given a online training of 30-45 minutes covering dysmenorrhea and coping in a single session. From the first menstrual cycle after the training session is completed, measurements will be made in 3 consecutive menstrual cycles
Study: NCT05804227

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ulixertinib
Description: Participants will take ulixertinib by mouth 2 times every day until the night before your surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ulixertinib
Description: Participants will take ulixertinib by mouth 2 times every day until the night before your surgery.
Study: NCT06229873

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: App-Based Inspiratory Muscle Strength Training
Description: Participants will perform inspiratory muscle strength training guided by a smartphone application. Participants will perform 30 breaths a day at 75% of maximal inspiratory pressure, 6 days a week, for 6 weeks. All training sessions will be guided by the smartphone application.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Clinic-Based Inspiratory Muscle Strength Training
Description: Participants will perform inspiratory muscle strength training guided by researchers. Participants will perform 30 breaths a day at 75% of maximal inspiratory pressure, 6 days a week, for 6 weeks. One training session each week will be performed in the research clinic.
Study: NCT05752266

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: AMILI Probiotic pills
Description: AMILI (AMILI Pte Ltd) will analyze stool samples provided by participants, and assign each participant a type of probiotic pill from the 5 different types of probiotic pills commercially available in AMILI retail store.
Study: NCT05766254

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active 10-Hz TMS to the DLPFC
Description: The active group will receive 10hz TMS stimulation. Participants in the active stimulation group will receive10-Hz TMS to left DLPFC. The LDLPFC will be based on 4 targeting neuroimaging methods (cortical thickness, fMRI, diffusion imaging, functional connectivity). TMS will be delivered using a robotic neuronavigation system (Smartmove, ANT). Stimulation intensity will be standardized at 110% of RMT and adjusted to the skull to cortical surface based on e-field calculations (simnibs). Stimulation will be delivered to the L-DLPFC using a active/placebo figure-8 coil and a magventure TMS device.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham TMS-DLPFC
Description: The parameters in the active arms will be as above with the internal randomization of the device internally switching to sham in a blinded fashion.
Study: NCT06529692

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Split-Belt Training
Description: Walking on a split-belt treadmill in which the belt under the ACL leg will move at a speed that is minimally slower than the other belt.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Split-Belt Training
Description: Walking on a split-belt treadmill in which the treadmill belt under the ACL leg will move at a speed faster or slower than the belt under the Non-ACL leg.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Split-Belt Training
Description: Walking on a split-belt treadmill in which the treadmill belt under the ACL leg will move at a speed faster or slower than the belt under the Non-ACL leg.
Study: NCT05465096

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Micro-fragmented adipose tissue injection
Description: Intra-articular ultrasound-guided injection of MF-AT
Study: NCT05317806

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin Extended Release Oral Tablet
Description: daily metformin treatment vs. no treatment with metformin
Study: NCT06296706

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel for injection (Albumin-bound)
Description: Docetaxel for injection (Albumin-bound), by intravenous infusion, every 3 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Taxotere (docetaxel)
Description: Taxotere, by intravenous infusion, every 3 weeks.
Study: NCT06553898

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-BCMA/CD70 CAR-T cells
Description: Three dose groups (0.3×105/kg, 1×105/kg, 3×105/kg) were set up, starting from the low dose group climbing to explore the safe and effective dose.
Study: NCT06637670

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiology taping
Description: 'Y shaped' kinesiology taping was applied on quadriceps femoris muscle, based on facilitation technique with 25-50% stretching.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo taping
Description: A tape without tension was applied perpendicular on the quadriceps femoris muscle.
Study: NCT06168669

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: xBar system
Description: xBar system is surgical drain with embedded sensors. Collected data will be evaluated for an ability to identify anastomotic leaks. The xBar system does not have therapeutic indication.
Study: NCT04782180

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Descovy 200Mg 25Mg Tablet
Description: daily Descovy tab by mouth

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PrEP
Description: PrEP will be provided in a community setting by community-based harm reduction program.
Study: NCT05353751

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kind Minds Program
Description: The KMP intervention uses an online mindfulness phone based program. During the 9-week program, Community Health Worker (CHW) Kindness Coaches will meet weekly for 30 minutes via Zoom with either a) the caregiver and adolescent (in separate meetings), or b) the adolescent only to review and complete a new session using the online mindfulness program. Participants will be prompted to complete mindfulness activities between sessions by notifications, conducive to their school and work schedules. Weekly content and meditations/activities focus on mindfulness skills of present moment awareness, nonjudgment, compassion, and gratitude.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Kind Minds Program
Description: The KMP intervention uses an online mindfulness phone based program. During the 9-week program, Community Health Worker (CHW) Kindness Coaches will meet weekly for 30 minutes via Zoom with either a) the caregiver and adolescent (in separate meetings), or b) the adolescent only to review and complete a new session using the online mindfulness program. Participants will be prompted to complete mindfulness activities between sessions by notifications, conducive to their school and work schedules. Weekly content and meditations/activities focus on mindfulness skills of present moment awareness, nonjudgment, compassion, and gratitude.
Study: NCT04677595

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capmatinib
Description: 400 mg of capmatinib tablets, administered orally twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capmatinib
Description: 400 mg of capmatinib tablets, administered orally twice daily
Study: NCT04619888

Intervention type: DIAGNOSTIC_TEST
Intervention: HeartLogic
Description: In case of HeartLogic index ≥16, the investigator will contact the patient to assess the patient's clinical condition and possibly adjust the heart failure treatment. The management will be standardized across centers according to the Manage-HF protocol.
Study: NCT06557343

Intervention type: DIAGNOSTIC_TEST
Intervention: Single Cell Sequencing
Description: Sequencing of all viable single cells present in deep bronchial brushings using transcriptomics to identify what cells are present and what they are doing.
Study: NCT05752266

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo pills
Description: Placebo pills contaning maltodextrin with similar appearance to Probiotic pills will be provided to participants allocated to the Placebo Arm.
Study: NCT04639037

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automated adjustment of vasopressor
Description: The objective of this randomized controlled superiority study is to demonstrate that, in patients admitted to intensive care after a major surgery, tight control of MAP using a closed-loop system for vasopressor administration will result in MAP being more often within a MAP range of 80-90 mmHg compared to the same management without this automated closed-loop system (nurse adjustment of vasopressor administration)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual adjustment of vasopressor
Description: Fluid and vasopressor will be delivered as standard of care (manual adjustment of both fluid and vasopressor infusion rate by the nurse)
Study: NCT04082767

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Precedex
Description: Precedex, dexmedetomidine hydrochloride, IV, 4mcg/mL, infusion duration determined by the clinical care team

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam
Description: Midazolam, IV, 5mg/mL (for patients more than 10kg), 1mg/mL (for patients 2-10kg), infusion duration determined by the clinical care team
Study: NCT06115252

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing (MI)
Description: Motivational interviewing with peer dyads starts with an open-ended exploration of the dyad's hazardous drinking behavior via personal stories about alcohol use. It includes a values clarification task and age-matched norms along with personalized feedback regarding the dyad's alcohol use. The goal of the session is to engage the dyad in a thoughtful conversation about drinking and the implications it may have on their lives, with an eye to bolstering and supporting inherent drive for behavior change.
Study: NCT06088095

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobility group
Description: Patients will be mobilized in accordance with the gradual mobilization procedure 12 hours after the angiography procedure.