Study: NCT06455969

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin 3.6 MG
Description: Goserelin acetate (Zoladex) is a gonadotropin-releasing hormone agonist (GnRH). GnRH agonists induce a transient increase in sex hormone concentrations, but subsequently inhibit gonadotropin secretion and the production of testosterone in men and estrogen in women. An equilibration period will occur to allow steroid concentrations to reduce.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin 3.6 MG
Description: Goserelin acetate (Zoladex) is a gonadotropin-releasing hormone agonist (GnRH). GnRH agonists induce a transient increase in sex hormone concentrations, but subsequently inhibit gonadotropin secretion and the production of testosterone in men and estrogen in women. An equilibration period will occur to allow steroid concentrations to reduce.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin 3.6 MG
Description: Goserelin acetate (Zoladex) is a gonadotropin-releasing hormone agonist (GnRH). GnRH agonists induce a transient increase in sex hormone concentrations, but subsequently inhibit gonadotropin secretion and the production of testosterone in men and estrogen in women. An equilibration period will occur to allow steroid concentrations to reduce.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin 3.6 MG
Description: Goserelin acetate (Zoladex) is a gonadotropin-releasing hormone agonist (GnRH). GnRH agonists induce a transient increase in sex hormone concentrations, but subsequently inhibit gonadotropin secretion and the production of testosterone in men and estrogen in women. An equilibration period will occur to allow steroid concentrations to reduce.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-Stressor Training
Description: A 4-week physical training program that mimics military training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-Stressor Training
Description: A 4-week physical training program that mimics military training.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Multi-Stressor Training
Description: A 4-week physical training program that mimics military training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-Stressor Training
Description: A 4-week physical training program that mimics military training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-Stressor Training
Description: A 4-week physical training program that mimics military training.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Testosterone gel (AndroGel 5g)
Description: Male subjects will be randomly assigned to receive a topical testosterone gel (5g dose).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Testosterone gel (AndroGel 1.25g)
Description: Male subjects will be randomly assigned to receive a topical testosterone gel (1.25g dose).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Estradiol / Levonorgestrel Transdermal System [Climara Pro]
Description: Female subjects will be randomly assigned to receive a estrogen/ progesterone patch.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Patch
Description: Female subjects will be randomly assigned to receive a placebo patch identical to the Climara Pro patch.