TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06148194

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% NaCl physiological saline
Description: Nasal-spraying 0.9% NaCl physiological saline is prepared by extracting 5 mL from 0.9% NaCl intravenous infusion 500 mL PP bottle (B.Braun, Germany, product declaration No. Nasal-spraying 0.9% NaCl physiological saline is prepared by extracting 30 mL from 0.9% NaCl intravenous infusion 500 mL PP bottle (B.Braun, Germany, product declaration No. VD-32732-19), and then pouring it into the same opaque plastic spraying 30 mL-bottle that is used for probiotic 1 and 2.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Probiotic 1
Description: In Vietnam, LiveSpo Navax is manufactured as a Class-A medical device (Product declaration: No. 210001337/PCBA-HN) in accordance with manufacturing standards approved by the Hanoi Health Department, Ministry of Health, Vietnam (Certificate No. YT117-19), and ISO 13485:2016. LiveSpo Navax product is prepared in the form of NaCl 0.9% plus B. subtilis and B. clausii at 1 billion CFU/mL x 30 mL.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Probiotic 2
Description: In Vietnam, LiveSpo Navax Kid is manufactured as a Class-A medical device (Product declaration: No. 220002534/PCBA-HN) in accordance with manufacturing standards approved by the Hanoi Health Department, Ministry of Health, Vietnam (Certificate No. YT117-19), and ISO 13485:2016. LiveSpo Navax Kid is prepared in the form of NaCl 0.9% plus B. subtilis and B. clausii at 0.6 billion CFU/mL x 30 mL.
Study: NCT06146998

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D health education model
Description: explanation combined with 3D health education model

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Verbal explanation
Description: Regular explanation
Study: NCT06269523

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio taping, Lymphatic drainage
Description: Kinesio tape, is an elastic cotton strip with an acrylic adhesive that is purported to ease pain and disability from athletic injuries and a variety of other physical disorders. The application of Kinesio Tex Tape facilitates the opening of microvalves due to a dynamic pressure variation due to alteration in skin density. This decompression activates lymphatics in the dermis and improves lymphatic flow. The end result is a tissue inflammation and swelling reduction.It has been applied at the end over every session after lymphatic dreinage (see below).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lymphatic drainage
Description: Lymphatic drainage is a type of manual manipulation of the skin based on the hypothesis that it will encourage the natural drainage of the lymph, which carries waste products away from the tissues back toward the heart. The lymph system depends on intrinsic contractions of the smooth muscle cells in the walls of lymph vessels (peristalsis) and the movement of skeletal muscles to propel lymph through the vessels to lymph nodes and then to the lymph ducts, which return lymph to the cardiovascular system. Manual lymph drainage uses a specific amount of pressure and rhythmic circular movements to stimulate lymph flow.
Study: NCT05106361

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MOSAIC Plus
Description: Those in the experimental arm will receive the intervention is called Mother AdvocateS In the Community (MOSAIC) Plus, an intervention to reduce depressive and PTSD symptoms and prevent additional intimate partner violence among pregnant women and mothers with children under 5 experiencing IPV. The MOSAIC Plus intervention will integrate interpersonal psychotherapy principles and skills into the MOSAIC intervention in order to expand it to address consequences of IPV, including depression and PTSD symptoms.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MOSAIC
Description: Those in the active comparator will receive a mentor mother intervention named Mother AdvocateS In the Community (MOSAIC). This does not include the IPT component.
Study: NCT05902585

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality
Description: In the virtual reality group, patients will view a video with the virtual reality glasses from the beginning to the end of the venipuncture.
Study: NCT06059586

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pelvic health therapy
Description: Female Sexual Function Index (FSFI) and VAS Pain Scale Questionnaires, Physical Therapy Evaluation including Pelvic Floor Muscle Examination, Dilator Education

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dilator feasability
Description: Patient Adherence to Vaginal Dilation Questionnaire
Study: NCT05932732

Intervention type: DEVICE
Group type: OTHER
Intervention: HydraFacial Syndeo System
Description: Utilizing patented Vortex Fusion Technology, a pneumatic device, the HydraFacial Syndeo system cleanses, exfoliates, and hydrates the skin.

Intervention type: DRUG
Group type: OTHER
Intervention: ReGen-GF
Description: The Regen-GF Booster, a serum formulated to increase collagen and elastin production, will be used during each HydraFacial treatment using the HydraFacial handpiece and specialized tip for application. Ingredients include Heptapeptide-32 maintains the appearance of healthy, youthful skin through collagen and elastin production, Copper Peptide Cu-GHK regenerates healthy-looking skin by accelerating wound healing and skin repair, Palmitoyl Tetrapeptide-7 treats inflammation while boosting the growth of collagen-producing tissues, Palmitoyl Tripeptide-5 helps skin cells flush toxins while enhancing the appearance of firmness, Azelaoyl Bis-Dipeptide 10 addresses signs of aging by managing the formation of free radicals, K3 Vitamin C promotes collagen synthesis, and Hyaluronic Acid hydrates the skin.

Intervention type: DRUG
Group type: OTHER
Intervention: ReGen-GF
Description: The Regen-GF Booster, a serum formulated to increase collagen and elastin production, will be used during each HydraFacial treatment using the HydraFacial handpiece and specialized tip for application. Ingredients include Heptapeptide-32 maintains the appearance of healthy, youthful skin through collagen and elastin production, Copper Peptide Cu-GHK regenerates healthy-looking skin by accelerating wound healing and skin repair, Palmitoyl Tetrapeptide-7 treats inflammation while boosting the growth of collagen-producing tissues, Palmitoyl Tripeptide-5 helps skin cells flush toxins while enhancing the appearance of firmness, Azelaoyl Bis-Dipeptide 10 addresses signs of aging by managing the formation of free radicals, K3 Vitamin C promotes collagen synthesis, and Hyaluronic Acid hydrates the skin.
Study: NCT05703633

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: uDCD treatment
Description: Thrombolytic treatment/prevention ex-vivo to kidneys procured from patients after circulatory arrest
Study: NCT06396182

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: group (A ) study group :virtual reality cycling by fully immersive Head-Mounted Display virtual reality (Oculus Quest virtual reality (VR) headset with hand controller).
Description: group (A ) study group : virtual reality cycling by fully immersive Head-Mounted Display virtual reality (Oculus Quest virtual reality (VR) headset with hand controller):~The VR cycling session utilized the VZFIT VR Exercise Bike (VZFIT, Cambridge, MA), games were selected as preliminary pilot trials indicated these games to be most intense. Players maneuvered during VR gameplay by pedaling and steering their virtual character by leaning their bodies left and right. (Daniel et al., 2020).~group (B) control group :Cycling by traditional stationary bike: Participants will require to continuously pedal using the pulse oximeter for HR monitor. Research personnel monitored participants during the session adjusting pedal-resistance to ensure that the participants stayed within their target HR zone. (Daniel et al., 2020).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: group (A ) study group :virtual reality cycling by fully immersive Head-Mounted Display virtual reality (Oculus Quest virtual reality (VR) headset with hand controller).
Description: group (A ) study group : virtual reality cycling by fully immersive Head-Mounted Display virtual reality (Oculus Quest virtual reality (VR) headset with hand controller):~The VR cycling session utilized the VZFIT VR Exercise Bike (VZFIT, Cambridge, MA), games were selected as preliminary pilot trials indicated these games to be most intense. Players maneuvered during VR gameplay by pedaling and steering their virtual character by leaning their bodies left and right. (Daniel et al., 2020).~group (B) control group :Cycling by traditional stationary bike: Participants will require to continuously pedal using the pulse oximeter for HR monitor. Research personnel monitored participants during the session adjusting pedal-resistance to ensure that the participants stayed within their target HR zone. (Daniel et al., 2020).
Study: NCT05820659

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: peer rejection task and impossible puzzle task
Description: Peer rejection task: Adolescents will be informed that two peers will take turns to choose who they will chat with for different topics. Participants will not be chosen by virtual White peers 75% of the time. In reality, White peers are computerized avatars and whether or not adolescents are chosen by those peers is programmed with PsychoPy software.~Impossible puzzle task: Adolescents will be asked to fit all puzzle pieces into a wooden frame with a wrong piece provided.
Study: NCT05409378

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The HLT® Meridian® TAVR Valve (Meridian® with TriVentTM Anticalcification Treatment Valve and Pathfinder® Delivery System)
Description: Aortic valve replacement with the HLT Meridian TAVR Valve to treat aortic regurgitation
Study: NCT04998201

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-APOC3
Description: ARO-APOC3 Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-APOC3
Description: ARO-APOC3 Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-APOC3
Description: ARO-APOC3 Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-APOC3
Description: ARO-APOC3 Injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sterile Normal Saline (0.9% NaCl)
Study: NCT02551952

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MentalPlus®
Description: Validate the MentalPlus® digital game as neuropsychological test of cognitive assessment pre and postoperative on study the internal consistency and validity of content and construct (convergent) MentalPlus® of the evaluated patients. Study the influence of age, gender and level of education of surgical patients in performance for the use of electronic devices (laptop, tablet, mobile) and digital games. Investigate the rehabilitation capacity of cognitive functions after training sessions with MentalPlus® game. Evaluate the effect of training with MentalPlus® game in brain networks involved in executive function, memory and attention by means of fMRI this is a brain imaging study.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: MentalPlus®
Description: Validate the MentalPlus® digital game as neuropsychological test of cognitive assessment pre and postoperative on study the internal consistency and validity of content and construct (convergent) MentalPlus® of the evaluated patients. Study the influence of age, gender and level of education of surgical patients in performance for the use of electronic devices (laptop, tablet, mobile) and digital games. Investigate the rehabilitation capacity of cognitive functions after training sessions with MentalPlus® game. Evaluate the effect of training with MentalPlus® game in brain networks involved in executive function, memory and attention by means of fMRI this is a brain imaging study.
Study: NCT04405765

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NPWT and lyopreserved Stravix
Description: Subjects will be treated with NPWT and lyopreserved Stravix

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NPWT and cryopreserved Stravix
Description: Subjects will be treated with NPWT and lyopreserved Stravix
Study: NCT04598074

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Opioid Package Prototype (OPP)
Description: The Opioid Package Prototype (OPP) is a child-resistant/senior-friendly, calendar-blister packaging of limited pill counts with flat readable billboard space for medication labeling.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care (standard amber vial)
Description: The standard amber vial (orange bottle) is the container that medication is normally dispensed in outside of the study.
Study: NCT04849650

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amisulpride IV
Description: A single 10mg IV dose of Amisulpride given over 1 minute

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amisulpride IV
Description: A single 10mg IV dose of Amisulpride given over 1 minute

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amisulpride Oral Tablet
Description: A single 10mg dose given as an oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amisulpride Oral Tablet
Description: A single 10mg dose given as an oral tablet
Study: NCT05932732

Intervention type: DEVICE
Group type: OTHER
Intervention: HydraFacial Elite MD System
Description: Utilizing patented Vortex Fusion Technology, the HydraFacial Elite MD system cleanses, exfoliates, and hydrates the skin.
Study: NCT06467734

Intervention type: DEVICE
Intervention: Joint aspiration
Description: Joint puncture to extract joint fluid.

Intervention type: DEVICE
Intervention: Joint aspiration
Description: Joint puncture to extract joint fluid.
Study: NCT06334198

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Naldemedine
Description: Naldemedine is administered orally once daily in the morning in a dosage of 0.2 mg.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is administered orally once daily in the morning.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol
Description: In both arms, tramadol is administered orally twice daily in a dosage of 100 mg (daily total of 200mg).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tramadol
Description: In both arms, tramadol is administered orally twice daily in a dosage of 100 mg (daily total of 200mg).
Study: NCT05441904

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PXL770
Description: A single dose of 500 and 750 mg was administered to each subject.
Study: NCT06201325

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: virtual reality based exercises
Description: play VR games

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional physical therapy
Description: streching and strengthening exercises

Intervention type: OTHER
Group type: OTHER
Intervention: home exercises program
Description: home exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: home exercises program
Description: home exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: home exercises program
Description: home exercises
Study: NCT05272917

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sensorial tests
Description: Patients will be included in the study between 3 to 6 months after the end of treatment and go to the Paul Bocuse Research Institute to perform several sensorial tests. The same sensorial tests will be completed by healthy volunteers to compare.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sensorial tests
Description: Patients will be included in the study between 3 to 6 months after the end of treatment and go to the Paul Bocuse Research Institute to perform several sensorial tests. The same sensorial tests will be completed by healthy volunteers to compare.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sensorial tests
Description: Patients will be included in the study between 3 to 6 months after the end of treatment and go to the Paul Bocuse Research Institute to perform several sensorial tests. The same sensorial tests will be completed by healthy volunteers to compare.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: food preferences questionnaires
Description: Patients will be included in the study between 3 to 6 months after the end of treatment and go at Institut Paul Bocuse to complete food preferences questionnaires. The same questionnaires will be completed by healthy volunteers to compare.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: food preferences questionnaires
Description: Patients will be included in the study between 3 to 6 months after the end of treatment and go at Institut Paul Bocuse to complete food preferences questionnaires. The same questionnaires will be completed by healthy volunteers to compare.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: food preferences questionnaires
Description: Patients will be included in the study between 3 to 6 months after the end of treatment and go at Institut Paul Bocuse to complete food preferences questionnaires. The same questionnaires will be completed by healthy volunteers to compare.
Study: NCT03834298

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Four Food Elimination Diet
Description: Food allergens are thought to initiate eosinophilic inflammation and dietary elimination of trigger allergens is an effective treatment for EoE. Previous work demonstrates that in both children and adult EoE patients, the food antigens including cow's milk, wheat, egg, soy, peanut/tree nut and fish/shell fish, are the most common food triggers causing esophageal inflammation. Participants will be assigned to single arm treatment / intervention with a diet restricted of the four most common food allergens, milk, soy, wheat and egg, or a four food elimination diet (FFED). With the goal to optimize diet treatment, in Aim 2, eligible participants will undergo sequential food reintroductions based on protocol.
Study: NCT05658549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-acetyl cysteine
Description: N-acetyl cysteine dosage 600 mg and 1200 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-acetyl cysteine
Description: N-acetyl cysteine dosage 600 mg and 1200 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-acetyl cysteine
Description: N-acetyl cysteine dosage 600 mg and 1200 mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: N-acetyl cysteine
Description: N-acetyl cysteine dosage 600 mg and 1200 mg
Study: NCT04194970

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: With WBM smart insole system to monitor compliance of specified weight bearing limits data in live feedback on and off situations
Description: Weight Bearing Protocol (Duration: Post-Op. 6 week)~* Post-op 3 week non-weight bearing (%0 body weight of patient)~* Post- op 3 week touch down weight bearing (%10-%20 body weight of patient) Group I - monitoring with device while the live feedback mechanism turned on Group II- monitoring with device while the live feedback mechanism turned off

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: With WBM smart insole system to monitor compliance of specified weight bearing limits data in live feedback on and off situations
Description: Weight Bearing Protocol (Duration: Post-Op. 6 week)~* Post-op 3 week non-weight bearing (%0 body weight of patient)~* Post- op 3 week touch down weight bearing (%10-%20 body weight of patient) Group I - monitoring with device while the live feedback mechanism turned on Group II- monitoring with device while the live feedback mechanism turned off
Study: NCT02551952

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MentalPlus®
Description: Validate the MentalPlus® digital game as neuropsychological test of cognitive assessment pre and postoperative on study the internal consistency and validity of content and construct (convergent) MentalPlus® of the evaluated patients. Study the influence of age, gender and level of education of surgical patients in performance for the use of electronic devices (laptop, tablet, mobile) and digital games. Investigate the rehabilitation capacity of cognitive functions after training sessions with MentalPlus® game. Evaluate the effect of training with MentalPlus® game in brain networks involved in executive function, memory and attention by means of fMRI this is a brain imaging study.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MentalPlus®
Description: Validate the MentalPlus® digital game as neuropsychological test of cognitive assessment pre and postoperative on study the internal consistency and validity of content and construct (convergent) MentalPlus® of the evaluated patients. Study the influence of age, gender and level of education of surgical patients in performance for the use of electronic devices (laptop, tablet, mobile) and digital games. Investigate the rehabilitation capacity of cognitive functions after training sessions with MentalPlus® game. Evaluate the effect of training with MentalPlus® game in brain networks involved in executive function, memory and attention by means of fMRI this is a brain imaging study.
Study: NCT06101446

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lavander Aromatherapy
Description: Aromatherapy is one of the potential non-pharmacological methods. Lavender oil has been known to have calming properties and is one of the most effective aromatherapy oils. It reduces blood pressure and anxiety by stimulating the parasympathetic system
Study: NCT06158139

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: iC9-CAR.B7-H3 T cell infusion
Description: iC9-CAR.B7-H3 T cell product will be administered via intravenous injection over 5 - 10 minutes.
Study: NCT04879329

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: disitamab vedotin
Description: Given into the vein (IV; intravenous) every 2 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pembrolizumab
Description: Given by IV on Day 1 of each 6-week cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pembrolizumab
Description: Given by IV on Day 1 of each 6-week cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pembrolizumab
Description: Given by IV on Day 1 of each 6-week cycle.