TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06396871

Intervention type: DIAGNOSTIC_TEST
Intervention: Magentic Resonance Imaging (MRI) of the liver
Description: The exact calculation of liver fat with proton density fat fraction will take place with MRI.

Intervention type: DIAGNOSTIC_TEST
Intervention: Magentic Resonance Imaging (MRI) of the liver
Description: The exact calculation of liver fat with proton density fat fraction will take place with MRI.
Study: NCT04391049

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given IV

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Undergo radiation therapy

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Telomerase-specific Type 5 Adenovirus OBP-301
Description: Given by intratumoral injection
Study: NCT06372730

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ventilation/Perfusion Single Photon Emission Computed Tomography (V/Q SPECT/CT)
Description: All patients will undergo a V/Q SPECT/CT scan at inclusion.
Study: NCT06396871

Intervention type: DIAGNOSTIC_TEST
Intervention: Magentic Resonance Imaging (MRI) of the liver
Description: The exact calculation of liver fat with proton density fat fraction will take place with MRI.

Intervention type: DIAGNOSTIC_TEST
Intervention: Magentic Resonance Imaging (MRI) of the liver
Description: The exact calculation of liver fat with proton density fat fraction will take place with MRI.

Intervention type: DIAGNOSTIC_TEST
Intervention: Magentic Resonance Imaging (MRI) of the liver
Description: The exact calculation of liver fat with proton density fat fraction will take place with MRI.
Study: NCT04562168

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Autoderm® dermatology search engine (ML model) testing
Description: GP using a smartphone camera will take an image of the skin problem and will use the Autoderm ML interface to upload the anonymized image. The obtained predicted diagnosis will be recorded in case report form.
Study: NCT05661474

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fitostimoline ® hydrogel group
Description: Treatment of DFUs with Fitostimoline® hydrogel every day for 12 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Saline gauze group
Description: Treatment of DFUs with saline gauze every day for 12 weeks.
Study: NCT05481762

Intervention type: DEVICE
Intervention: Aided read with contextflow DETECT Lung CT
Description: Radiologists read chest CT scabs with and without the aid of contextflow DETECT Lung CT as a second reader
Study: NCT06534359

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transpyloric tube feeding
Description: Tube feeding into the small bowel

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gastric tube feeding
Description: Tube feeding into the stomach
Study: NCT04965844

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oxygen close-loop
Description: The Automatic FiO2 option provides automated adjustment of the ventilator Oxygen setting to maintain the patient's SpO2 in a defined target range. When using the software option, the user defines the SpO2 target range, as well as the SpO2 emergency limits, and the device adjusts the Oxygen setting to keep the patient's SpO2 in the target range.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: No intervention
Description: Manual FiO2 adjustment according to SpO2 values
Study: NCT05103267

Intervention type: DEVICE
Intervention: Tauropace
Description: TauroPace™ contains disinfecting substances to eradicate environmental microbial contamination on the surface of cardiac implantable electronic devices (CIEDs). The surface of the CIED is moistened with TauroPace™ during the implantation procedure to create a hostile environment on the surface of the CIED.
Study: NCT05998733

Intervention type: DIAGNOSTIC_TEST
Intervention: Early general coagulation function (5 items of coagulation) and thromboelastogram monitoring
Description: * Correlation analysis of sepsis severity with FDP and D-Dimer~* Discussion on the critical value and area under the curve of FDP and D-Dimer in diagnosis of sepsis~* Differences in age and sex of FDP and D-Dimer in diagnosis of sepsis~* Effect of FDP and D-Dimer diagnosis of sepsis on severe conversion rate and all-cause mortality of patients~* The difference of thromboelastogram in patients with sepsis of different severity~* Thromboelastogram items (R time α Correlation between angle, k time, maximum blood clot strength and comprehensive coagulation index) and sepsis

Intervention type: DIAGNOSTIC_TEST
Intervention: Early general coagulation function (5 items of coagulation) and thromboelastogram monitoring
Description: * Correlation analysis of sepsis severity with FDP and D-Dimer~* Discussion on the critical value and area under the curve of FDP and D-Dimer in diagnosis of sepsis~* Differences in age and sex of FDP and D-Dimer in diagnosis of sepsis~* Effect of FDP and D-Dimer diagnosis of sepsis on severe conversion rate and all-cause mortality of patients~* The difference of thromboelastogram in patients with sepsis of different severity~* Thromboelastogram items (R time α Correlation between angle, k time, maximum blood clot strength and comprehensive coagulation index) and sepsis
Study: NCT05139407

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Teaching intervention
Description: Different teaching methods are used to teach the experimental group and the control array in the classroom.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Teaching intervention
Description: Different teaching methods are used to teach the experimental group and the control array in the classroom.
Study: NCT05189561

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: near-infrared scanner
Description: Tests to be administered: Near Infra-Red Scanning of the head at the bedside.~Time taken for testing: Two minutes~Biological samples collected: None~Frequency of testing/collection: Once~Risks for the participants while being tested: None
Study: NCT05278585

Intervention type: PROCEDURE
Intervention: RAP TAVI
Description: All patients undergoing TAVI with no pre-existing pacemaker and in sinus rhythm at the time of the procedure will receive RAP by placing the temporary wire in the right atrium
Study: NCT05605028

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mental Health lifestyle intervention
Description: The focus is to identify 10 potential groups of causes and working on reversing them. The 10 factors are: (1) Genetic, (2) Developmental, (3) Lifestyle, (4) Circadian Rhythm, (5) Addiction, (6) Nutrition, (7) Toxic, (8) Social/Complicated Grief, (9) Medical Condition, and (10) Frontal Lobe. Each of these factors will be dealt with in the lifestyle intervention.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietitian-led
Description: A group of people that visit the dietitian will be used as comparison against the Mental Health lifestyle intervention
Study: NCT05329090

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab Injection
Description: anti-CD20 monoclonal antibody leading to B-cell depletion, in relapsing and/or refractory IgAV patients

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo experimental treatment
Study: NCT05103397

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: methyl prednisolone
Description: Low dose group .Group (A) 10 mg/Kg methyl prednisolone will be received after induction and before separation to (CPB).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methyl Prednisolonate
Description: High dose group.Group (B) 30 mg/Kg will be received after induction and before separation (CPB)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo group.Group (C) (25 patients) patients will receive placebo in form of normal saline
Study: NCT06529991

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Occipivot suboccipital pillow self-myofascial release
Description: Subjects will be instructed in the use of the Occipivot suboccipital pillow and how it should feel. They will be supervised as it is placed. Once verbal verification is obtained regarding the feel and placement of the wedge, the treatment time will begin and continue for 5 minutes.
Study: NCT06471049

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Benign Hysterectomy
Description: removal of the uterus

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Benign Hysterectomy
Description: removal of the uterus

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Benign Hysterectomy
Description: removal of the uterus
Study: NCT05057130

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin, Cisplatin, Methotrexate
Description: IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin, Cisplatin
Description: IV
Study: NCT06534762

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mirabegron
Description: To explore the efficacy and safety of milaberon combined with standard treatment in advanced solid tumors
Study: NCT06181214

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: AG1 - Nutritional Supplement
Description: A foundational nutritional supplement consisting of vitamins, minerals, probiotics, prebiotics, and whole food ingredients

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Maltodextrin placebo
Study: NCT05272293

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NK cell infusions
Description: Three doses of expanded haploidentical NK cells (30-100 x 10\^6 cells /kg).
Study: NCT05204680

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise
Description: The participant will work with the physical therapist on an exercise regimen.
Study: NCT05714865

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surfactant
Description: Laryngoscopy is performed, and BLES® surfactant is administered through BLEScath™ (a thin catheter) into the trachea to a spontaneously breathing preterm infant with respiratory distress syndrome who is being managed on CPAP
Study: NCT05511870

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etripamil Nasal Spray 70mg
Description: Etripamil NS 70 mg will be administered via the Aptar Pharma Nasal Spray Bidose System, supplied as prefilled devices packaged into child-resistant boxes with instructions for use provided in the study drug box.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered via the Aptar Pharma Nasal Spray Bidose System, supplied as prefilled devices packaged into child-resistant boxes with instructions for use provided in the study drug box.
Study: NCT06485921

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ischemic compression
Description: Participants will received a total of 12 treatment sessions over 6 weeks, with 2 sessions per week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Instrument assisted soft tissue mobilization Group
Description: Participants will received a total of 12 treatment sessions over 6 weeks, with 2 sessions per week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise and workplace modifications
Description: Participants will receive stretching and strengthening exercises for neck and scapular stabilizer muscles as a 6-week home program.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise and workplace modifications
Description: Participants will receive stretching and strengthening exercises for neck and scapular stabilizer muscles as a 6-week home program.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise and workplace modifications
Description: Participants will receive stretching and strengthening exercises for neck and scapular stabilizer muscles as a 6-week home program.
Study: NCT04947007

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine hydrogen chloride (HCl) 0.025 % in 15+15 ML Injection
Description: In this group, US guided suprascapulary and axillary block will be performed with 15 ml +15 ml 0.025% bupivacaine for each block site using a 22 gauge 10 mm block needle.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl 0.025 % in 10+10 ML Injection
Description: In this group, US guided suprascapulary and axillary block will be performed with 10 ml +10 ml 0.025% bupivacaine for each block site using a 22 gauge 10 mm block needle.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl 0.025 % in 5+5 ML Injection
Description: In this group, US guided suprascapulary and axillary block will be performed with 5 ml +5 ml 0.025% bupivacaine for each block site using a 22 gauge 10 mm block needle.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isotonic solution
Description: In this group, US guided suprascapulary and axillary block will be performed with isotonic solution
Study: NCT05983601

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: The anode electrode will be placed at the midline of the Cz according to international 10-20 EEG system, and the cathode electrode will be placed at the midline of forehead. In this way, both hemisphere of motor cortex can be stimulated which is used as protocol in various balance studies (Siedel-Marzi and Ragert, 2020b; Saruco et al., 2017). Participants will continue their training with tDCS (2mA) for 20 minutes. This application will continue three times a week for four weeks. In the end of the study, participants will be asked to guess which group they were in (active or sham).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: The anode electrode will be placed at the midline of the Cz according to international 10-20 EEG system, and the cathode electrode will be placed at the midline of forehead. In this way, both hemisphere of motor cortex can be stimulated which is used as protocol in various balance studies (Siedel-Marzi and Ragert, 2020b; Saruco et al., 2017). Participants will continue their training with tDCS (2mA) for 20 minutes. This application will continue three times a week for four weeks. In the end of the study, participants will be asked to guess which group they were in (active or sham).
Study: NCT06213025

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: web-based Educational program promoting response and willingness to handle elderly
Description: promote the response and willingness of gerontological nurses in handling elderly abuse cases. By employing a rigorous experimental design, this research seeks to contribute evidence-based insights that can inform educational strategies to empower nurses in safeguarding the well-being of elderly individuals.
Study: NCT05641272

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 3,000 MM09
Description: Allergoid (Dermatophagoides pteronyssinus and Dermatophagoides farinae)-mannan conjugates (MM09) at 3.000 UTm/mL for sublingual immunotherapy.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 9,000 MM09
Description: Allergoid (Dermatophagoides pteronyssinus and Dermatophagoides farinae)-mannan conjugates (MM09) at 9.000 UTm/mL for sublingual immunotherapy.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo sublingual
Description: The same solution, presentation, method of administration, frequency, and duration as the active treatment, but without active ingredients.
Study: NCT04904432

Intervention type: GENETIC
Group type: OTHER
Intervention: PLIN1 gene sequencing
Description: One supplementary blood sample will be taken (compare to classical ACS treatment and follow up) to realize genetic analyse of PLIN1 gene, looking for mutations
Study: NCT04199780

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation
Description: Transcranial direct current stimulation (tDCS), stimulates specific areas of the brain via electric current passed through electrodes placed on the scalp. During tDCS, low amplitude direct currents penetrates the skull to enter the brain and modulates neuronal activity.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation
Description: Transcranial direct current stimulation (tDCS), stimulates specific areas of the brain via electric current passed through electrodes placed on the scalp. During tDCS, low amplitude direct currents penetrates the skull to enter the brain and modulates neuronal activity.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation
Description: Transcranial direct current stimulation (tDCS), stimulates specific areas of the brain via electric current passed through electrodes placed on the scalp. During tDCS, low amplitude direct currents penetrates the skull to enter the brain and modulates neuronal activity.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Direct Current Stimulation
Description: Transcranial direct current stimulation (tDCS), stimulates specific areas of the brain via electric current passed through electrodes placed on the scalp. During tDCS, low amplitude direct currents penetrates the skull to enter the brain and modulates neuronal activity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral (CB) intervention
Description: CBI generally consist of cognitive coping strategies (e.g., distraction, relabeling, reducing pain-catastrophizing) and self-management (e.g., relaxation strategies, guided imagery) designed to enhance perceived control and reduce sympathetic nervous system tone.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral (CB) intervention
Description: CBI generally consist of cognitive coping strategies (e.g., distraction, relabeling, reducing pain-catastrophizing) and self-management (e.g., relaxation strategies, guided imagery) designed to enhance perceived control and reduce sympathetic nervous system tone.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral (CB) intervention
Description: CBI generally consist of cognitive coping strategies (e.g., distraction, relabeling, reducing pain-catastrophizing) and self-management (e.g., relaxation strategies, guided imagery) designed to enhance perceived control and reduce sympathetic nervous system tone.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Cognitive-Behavioral (CB) intervention
Description: CBI generally consist of cognitive coping strategies (e.g., distraction, relabeling, reducing pain-catastrophizing) and self-management (e.g., relaxation strategies, guided imagery) designed to enhance perceived control and reduce sympathetic nervous system tone.
Study: NCT05950633

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Participants will receive standard of care postoperative instructions

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Recovery
Description: Participants will receive instructions to increase their fitness to walking at least 30 minutes a day for 5 days a week following surgery and abdominal and pelvic floor exercises will focus on abdominal wall strengthening and abdominal pressure management, urinary urgency and retention, bowel and constipation management
Study: NCT06341751

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological treatment for persistent fatigue
Description: The treatment consists of three main phases: 1) goal-setting; stabilizing sleep-wake patterns and even distribution of activities over the day (pacing). Attention-shifting and cognitive reappraisal 2. Gradual increase in physical activity followed by gradual increase in mental and social activity 3. Individual work to reach treatment goals.
Study: NCT05362188

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Nicotinamide Topical
Description: Patients with discoid lupus erythematosus (face \& scalp) will be given topical nicotinamide in two concentrations (2\&4%) to apply twice daily for 12 consecutive weeks and then follow up.~Topical nicotinamide will be prepared in different forms (cream \& gel).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotinamide Topical
Description: Patients with discoid lupus erythematosus (face \& scalp) will be given topical nicotinamide in two concentrations (2\&4%) to apply twice daily for 12 consecutive weeks and then follow up.~Topical nicotinamide will be prepared in different forms (cream \& gel).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotinamide Topical
Description: Patients with discoid lupus erythematosus (face \& scalp) will be given topical nicotinamide in two concentrations (2\&4%) to apply twice daily for 12 consecutive weeks and then follow up.~Topical nicotinamide will be prepared in different forms (cream \& gel).
Study: NCT04831736

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: Ketamine at a dose of 0.6 mg/kg will be administered intravenously (IV) while the participant is recovering in the PACU. The study drug will be administered over at least 30 minutes at one time point and will be administered after subject has been deemed to be stable (hemodynamically stable, awake) by the study team on POD 0.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching equal dose of saline placebo will be administered intravenously while the participant is recovering in the PACU.
Study: NCT06533241

Intervention type: PROCEDURE
Intervention: renal biopsy
Description: percutaneous renal biopsy procedure
Study: NCT04992715

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: [99mTc]-NM01 SPECT/CT
Description: Technetium-99m radiolabelled anti-PD-L1 single-domain antibody (NM01) single-photon emission computed tomography (SPECT)/computed tomography (CT)
Study: NCT05302466

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: gymnastics plus silicon dental bite pad
Description: Gymnastics (see below) plus dental bite pads. The dental bite pads TJ Motion (BELY Balance GmbH \& Co. KG, Weisendorf, Germany) are made of medical silicone. Accordingly, they are BPA- and latex-free, odourless, tasteless and dimensionally stable. The splints are placed on the back molars of the lower jaw and remain in this position in the mouth for 3 minutes during the exercise. After use, the splints are rinsed with water and placed dry in the corresponding storage box.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: gymnastics only
Description: Gymnastics, which are completed daily (7x/week), each consist of three to six exercises and have a total duration of three minutes. The gymnastic programme contain low-intensity exercises from functional gymnastic or physiotherapy.
Study: NCT05806801

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MICT Exercise
Description: Subjects randomized into this group will complete a moderate intensity continuous exercise 4 days/week.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: No Exercise (Control)
Description: Subjects randomized into this group will remain sedentary throughout the duration of the study.