TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05576467

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MBCT-Telephone
Description: Classes follow MBCT protocol delivered via telephone by a master's level or higher mental health provider under the supervision of a licensed clinical psychologist, following treatment fidelity guidelines from NIH's Behavioral Change Consortium.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MBCT-Video
Description: Classes follow MBCT protocol delivered via video by a master's level or higher mental health provider under the supervision of a licensed clinical psychologist, following treatment fidelity guidelines from NIH's Behavioral Change Consortium.
Study: NCT06416943

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D printed educational model
Description: Slide-based presention plus 3D printed port-A catheter model
Study: NCT05066425

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Soluble Corn Fiber
Description: Participants will be asked to consume a packet of 22g Soluble Corn Fiber/day for 4 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Participants will be asked to consume a packet of 22g Maltodextrin/day for 4 weeks
Study: NCT06155344

Intervention type: OTHER
Intervention: Food Frequency Questionnaire
Description: We will obtain a global index of vegetalization of the diet (the Plant based Diet Index: PDI) from data obtained using semi-quantitative questionnaires on food frequency (Food Frequency Questionnaire (FFQ)) validated on the national ELFE cohort (French Longitudinal Study from Childhood (https://www.elfe-france.fr)) and completed by women in the 1st trimester of pregnancy (T1) and at delivery.

Intervention type: OTHER
Intervention: Collection of 4 mL maternal blood
Description: One tube collection of 4 mL maternal blood in the first trimester and at delivery.
Study: NCT05714592

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: The referring haematologist will suggest that the patient participate in the study during the consultation. In these patients, the investigators will perform OGM on the cytogenetic sample
Study: NCT06537440

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: electro-acupuncture
Description: Electroacupuncture ST25 Tianshu (double), TE6 Zhigou (double), LI4 Hegu (double), ST36 Ashisanli (double), ST37 Shangjuhu (double)
Study: NCT06039501

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Perspective Program
Description: The program involves regular meetings between families and an ICU support counselor. The ICU support counselor is a trained expert in providing culturally competent emotional and/or spiritual support. The ICU support counselor will support families and also learn and summarize family perspectives in a standardized report. ICU care team members will be prompted to perspective take as they review reports prior to regular routine meetings between families and the ICU care team.
Study: NCT04165746

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Foster Care
Description: Upon entry into the Child Protection System, if the child is assigned to one of the districts participating in the RCT, the court will notify the study team. Children that have been randomly assigned to Foster Care will be placed in a foster home within 48 hours of referral to the Family Court/Child Protection System.~Children and Foster Parents will receive biweekly visits from Social Workers. Children and Foster parents will also participate in the caregiving intervention described below. Children will remain in the placement until such time as the social workers, psychologists and Family Court Judge determine that one of the following outcomes is appropriate: reunification with biological family or adoption.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiving Intervention
Description: During AVI an intervenor meets with a caregiver (foster parent or caregiver at the institution) and child in the home environment. During each session, the intervenor videotapes the caregiver and child doing play-based activities. During that meeting, the intervenor reviews the videos with the caregiver and provides positive, constructive feedback to the caregiver. AVI is aimed at increasing sensitivity in parents/caregivers in order to encourage positive interactions. The guiding principles are to create a positive environment and to convey that the caregiver is the expert on their own child. The AVI methodology was selected to be used as a method of caregiving intervention with the study participants due to its demonstrated results in its use with children in contexts of social vulnerability, as well as families included in the child protection system. This will be the first time that AVI is being used in foster and institutional care in Brazil.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiving Intervention
Description: During AVI an intervenor meets with a caregiver (foster parent or caregiver at the institution) and child in the home environment. During each session, the intervenor videotapes the caregiver and child doing play-based activities. During that meeting, the intervenor reviews the videos with the caregiver and provides positive, constructive feedback to the caregiver. AVI is aimed at increasing sensitivity in parents/caregivers in order to encourage positive interactions. The guiding principles are to create a positive environment and to convey that the caregiver is the expert on their own child. The AVI methodology was selected to be used as a method of caregiving intervention with the study participants due to its demonstrated results in its use with children in contexts of social vulnerability, as well as families included in the child protection system. This will be the first time that AVI is being used in foster and institutional care in Brazil.
Study: NCT04629495

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rapamycin
Description: RAPA will be administered orally 1mg daily

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered orally once daily
Study: NCT04944043

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ05105 Tablet
Description: TQ05105 tablet is a Janus Kinase (JAK) inhibitor, which can inhibit the abnormal activation of JAK 2-V617F mutation, thereby inhibiting the sustained abnormal activation of JAK / STAT pathway.
Study: NCT05595967

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health education intervention
Description: Both the two session contains modules focusing on heath related knowledge and pelvic floor muscle exercise. Both two session will be delivered by primary healthcare women workers in small groups (about 20 women per group). The local healthcare workers are responsible for making appointment with each participant through group activities. Each participant will receive a healthy calendar practice to record the number of exercises per day which will be supervised by primary healthcare workers. All healthcare workers are required to attend a full-day workshop organized base on the scheme and teaching materials developed by our research team. The contents of the workshop include: (1) introduction of pelvic floor dysfunction; (2) risk factors and prevention of pelvic floor dysfunction; (3) kegel movement; (4) methods of dealing with severe illness; (5) a standard procedure of group activities or one-on-one activities; (6) skills needed for the delivery of health education intervention.
Study: NCT05265286

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FRSW117
Description: Subjects of high dose group are being received four doses(50 IU/kg,once a week or every 7 days) of FRSW117.~Subjects of low dose group (40 IU/kg,once a week or every 7 days)are being received four doses of FRSW117.
Study: NCT06461026

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: L9LS
Description: Administered intramuscularly one time.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: Administered intramuscularly one time.
Study: NCT05346939

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dynamic taping
Description: The athletic trainer will intervene with spiral dynamic technique by using a dynamic tape for the first test and a sham dynamic tape for the second test, or reverse the order.
Study: NCT04995302

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Microoneedling and Amnion Bilayer
Description: Microneedling is conducted following a three-week application of tretinoin cream. Then, scar tissue that has been treated with microneedling is covered with amnion bilayer for 72 hours.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Microoneedling
Description: Microneedling is conducted following a three-week application of tretinoin cream. Then, scar tissue that has been treated with microneedling is covered with an antibacterial gauze dressing.
Study: NCT04700215

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BiPAP
Description: To give bilevel positive airway pressure to the lungs

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Incentive spirometry
Description: IS for 15 minutes after every 4 hours
Study: NCT05576467

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care (EUC)
Description: Weekly online modules follow migraine and behavior principles delivered via web portal developed by a team of licensed clinical psychologists, neurologists, and mental health providers.
Study: NCT04897516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Short regimen of benznidazole
Description: Benznidazole, under the brand name Abarax (100 mg tablet), 300 mg divided into three daily doses (100 mg every 08 hours) for 2 weeks.
Study: NCT05234008

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High intensity training at home
Description: A HIT exercise intervention is performed. Four sessions are performed at REVAL Research Center to educate participants on the exercise protocol. Eight exercise sessions are performed at home with support of Physitrack (a mobile application for participants and a software platform for researchers).~In-center program (2 weeks, 4 sessions): Participants perform a concurrent exercise protocol of 1h-1.5h, as published by our research team previously, consisting of cardiorespiratory, general resistance, and core muscle training, all at high intensity.~Home sessions (4 weeks, 8 sessions): Researchers provide participants with a fitness bike, smartwatch, and training mat. Using Physitrack, researchers formulate a personalized HIT program to be performed at home for each participant by selecting from \>3500 exercises or insert a new exercise to add to the library. This HIT program resembles the program performed in the rehabilitation center as much as possible.
Study: NCT06653569

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baloxavir Marboxil
Description: The antiviral baloxavir marboxil administered in one unique dose.~1 capsule (40 mg) if participant weighs \< 80 kg; 2 capsules (80 mg) if participant weighs ≥ 80 kg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients in the placebo group will receive one unique dose of placebo. 1 capsule if participant weighs \< 80 kg; 2 capsules (80 mg) if participant weighs ≥ 80 kg.
Study: NCT04897516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Short treatment with benznidazole
Description: Benznidazole, under the brand name Abarax (100 mg tablet), 300 mg divided into three daily doses (100 mg every 08 hours) for 4 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard treatment with benznidazole
Description: Benznidazole, 300 mg divided into three daily doses (100 mg every 08 hours), orally for 8 weeks
Study: NCT05920031

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross-education
Description: Participants will perform resistance exercises at 60% of their 1 repetition maximum (1RM) with the less affected limb. The intervention will be performed three times per week for 8 weeks. Each session will consist of three sets of 15 repetitions of bicep curls, tricep extensions, and wrist flexion/extension exercises with a 1-minute rest period between sets. The exercises will be performed in a seated position, with the participant's forearm resting on a table and the therapist providing manual resistance. The therapist will be positioned in front of the participant.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross-education
Description: Participants will perform resistance exercises at 60% of their 1 repetition maximum (1RM) with the less affected limb. The intervention will be performed three times per week for 8 weeks. Each session will consist of three sets of 15 repetitions of bicep curls, tricep extensions, and wrist flexion/extension exercises with a 1-minute rest period between sets. The exercises will be performed in a seated position, with the participant's forearm resting on a table and the therapist providing manual resistance. The therapist will be positioned in front of the participant.
Study: NCT06416189

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fixed appliances
Description: MBT Brackets 0.022 inch
Study: NCT05920031

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror therapy
Description: Participants will perform bilateral upper limb movements while observing the reflection of the less affected limb in a mirror. The intervention will be performed three times per week for 8 weeks. Each session will consist of 10 minutes of mirror therapy, with the participant seated in front of a mirror. The participant will perform various upper limb movements, such as reaching and grasping, while observing the mirror reflection of the less affected limb. The therapist will be positioned beside the participant, providing verbal cues and feedback as necessary.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror therapy
Description: Participants will perform bilateral upper limb movements while observing the reflection of the less affected limb in a mirror. The intervention will be performed three times per week for 8 weeks. Each session will consist of 10 minutes of mirror therapy, with the participant seated in front of a mirror. The participant will perform various upper limb movements, such as reaching and grasping, while observing the mirror reflection of the less affected limb. The therapist will be positioned beside the participant, providing verbal cues and feedback as necessary.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy
Description: articipants will receive conventional rehabilitation for post-stroke upper limb motor impairments, which may include exercises such as range of motion, stretching, and strengthening of the affected limb, as well as other therapies such as electrical stimulation or constraint-induced movement therapy. The intervention will be individualized for each participant and will be performed three times per week for 8 weeks. The frequency, duration, and intensity of the exercises will be gradually increased over the course of the intervention, based on the participant's progress. The exercises may be performed in a seated or standing position, depending on the participant's ability and preference. The therapist will be positioned in front of or beside the participant, providing verbal cues and feedback as necessary.
Study: NCT05385276

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transverse supraumbilical incision
Description: The skin incision will be performed as a straight transverse skin incision 3-5cm above umbilicus after maximum retraction the panniculus caudally using two towel clips, to facilitate the approach to the lower uterine segment The skin incision is a transverse upward concavity, typically initiated two finger-breadths above the symphysis pubis and extended in the direction of the anterior superior iliac spine below and medial to it about (2 - 3 cm) .

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pfannenstiel Incision
Description: The skin incision is a transverse upward concavity, typically initiated two finger-breadths above the symphysis pubis and extended in the direction of the anterior superior iliac spine below and medial to it about (2 - 3 cm).
Study: NCT06442826

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-invasive auricular stimulation
Description: Single session TniAS stimulation will be achieved by applying four stimulation patches. These patches consist of stainless steel spheres with a diameter of 1.2 mm, covered with adhesive circular paper measuring 8 mm in diameter.~Point 1. Located in the Triangular Fossa, upper and central level at the vertex of the Fossa, at junction between the upper root and the lower root of the Antihelix.~Point 2. Located in the inner part of the Cymba (upper) conchae, in the angle formed by the lower root of the antihelix and the ascending branch of the Helix.~Point 3. Located in the middle depression of the Cavum (lower) conchae.~Poinit 4. It is located at the inner superior quadrant of Lobe, below the external curve of the Intertragus notch, in a depression 3-4 mm from the insertion of the lobe to the face.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham auricular stimulation (SAS)
Description: Sham intervention will be conducted following the exact same procedure as the TniAS group, with the only difference being the use of sham stimulation patches. These sham patches will consist of the same patches utilized in the TniAS group, except for the absence of the stainless steel spheres. During the application of these sham patches, the investigator will adhere to the identical process as in the TniAS group, with the exception that no palpation will be performed to locate the exact points, and only minimal pressure required for patch adherence will be applied to minimize any substantial stimulation. Participants in the SAS group will also be explicitly instructed not to stimulate the points until the removal of the patches.~The removal of the sham stimulation patches will follow the precise protocol applied in the TniAS group, ensuring consistency in the study procedures across both groups.
Study: NCT06574724

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visiting a green space
Description: Participants are asked to visit a green space for a defined time period
Study: NCT05415072

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DYP688
Description: Single agent DYP688

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DYP688
Description: Single agent DYP688

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DYP688
Description: Single agent DYP688

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DYP688
Description: Single agent DYP688
Study: NCT04741646

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ferric Citrate
Description: Auryxia® 210 mg ferric iron tablets equivalent to 1 g of FC and matching placebo will be supplied as 200 tablets in 400cc high-density polyethylene bottles.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match Ferric Citrate tablets
Study: NCT06608498

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SPARK Coping
Description: SPARK Coping is a single-session intervention providing psychoeducation and structured practices related to stigma reduction, cognitive restructuring, behavioral activation, and effective coping. It is a self-guided website powered by research data capture software.
Study: NCT06193889

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: KYV-101
Description: Anti-CD19 CAR-T cell therapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard lymphodepletion regimen
Description: Standard lymphodepletion regimen
Study: NCT04890158

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prone positioning for a total of 6 hours daily
Description: Prone positioning for 6 hours daily
Study: NCT05908539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Equipment box
Description: Participants receive a box of exercise equipment containing dumbbell, elastic band, hand cycle machine, and booklet of exercise instruction only.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Equipment box
Description: Participants receive a box of exercise equipment containing dumbbell, elastic band, hand cycle machine, and booklet of exercise instruction only.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Equipment box with briefing
Description: Participants receive a box of exercise equipment containing dumbbell, elastic band, hand cycle machine, and booklet of exercise instruction, and they are given verbal briefing on how to use the equipment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Equipment box with briefing
Description: Participants receive a box of exercise equipment containing dumbbell, elastic band, hand cycle machine, and booklet of exercise instruction, and they are given verbal briefing on how to use the equipment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Participants receive al box of exercise equipment. They attend an 8-week group exercise training program for 1 hour /session and 1 session/ week, and are supervised by a physical fitness training. The exercise program includes a combination of aerobic, resistance, balance and flexibility exercises.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training with behavioral modification
Description: Participants receive al box of exercise equipment. They attend an 8-week group exercise training program for 1 hour /session and 1 session/ week, and are supervised by a physical fitness training. The exercise program includes a combination of aerobic, resistance, balance and flexibility exercises. After finishing the exercise training program, a 6-week behavioral modification is provided. Two home visits and four telephone visits are conducted to empower the participants for exercise at home.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training with behavioral modification
Description: Participants receive al box of exercise equipment. They attend an 8-week group exercise training program for 1 hour /session and 1 session/ week, and are supervised by a physical fitness training. The exercise program includes a combination of aerobic, resistance, balance and flexibility exercises. After finishing the exercise training program, a 6-week behavioral modification is provided. Two home visits and four telephone visits are conducted to empower the participants for exercise at home.