TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05927870

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: pigtail
Description: placing a small amount of local anaesthetic subcutaneously at the site of the gallbladder, a skin incision was made through which the catheter was introduced. A 7-Fr pigtail catheter was used in all cases . If possible, the catheter was introduced into the gallbladder after passing through the liver. The catheter was thereafter fixed, either by an internal locking device or by means of a suture to the skin. The catheter was rinsed with saline solution daily in order to prevent clogging.
Study: NCT05965375

Intervention type: OTHER
Intervention: Observational; No Interventions were given.
Description: Observational; No Interventions were given.

Intervention type: OTHER
Intervention: Observational; No Interventions were given.
Description: Observational; No Interventions were given.

Intervention type: OTHER
Intervention: Observational; No Interventions were given.
Description: Observational; No Interventions were given.

Intervention type: OTHER
Intervention: Observational; No Interventions were given.
Description: Observational; No Interventions were given.

Intervention type: OTHER
Intervention: Observational; No Interventions were given.
Description: Observational; No Interventions were given.
Study: NCT05794334

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low Dye Taping
Description: This second group also contains 20 participents.French functional method is similar to the Ponseti method. In this technique, the patient undergoes 30-minute daily session for 2 weeks and then twice a week until achieving foot correction. It consists of stretching of triceps surae to improve tibio-talar joint function. daily manipulations of the newborn's foot, stimulation and strenghtening of the muscles around the foot (particularly the peroneal muscles) and temporary immobilization of the foot with elastic and nonelastic adhesive taping so that the reduction achieved by.The average time of this method ranges between 6 to 8 weeks, with all the deformities being corrected apart from equinus. This method reports a 93% success rate

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low Dye Taping
Description: This second group also contains 20 participents.French functional method is similar to the Ponseti method. In this technique, the patient undergoes 30-minute daily session for 2 weeks and then twice a week until achieving foot correction. It consists of stretching of triceps surae to improve tibio-talar joint function. daily manipulations of the newborn's foot, stimulation and strenghtening of the muscles around the foot (particularly the peroneal muscles) and temporary immobilization of the foot with elastic and nonelastic adhesive taping so that the reduction achieved by.The average time of this method ranges between 6 to 8 weeks, with all the deformities being corrected apart from equinus. This method reports a 93% success rate
Study: NCT06488482

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nivolumab or pembrolizumab
Description: See above

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nivolumab or pembrolizumab
Description: See above
Study: NCT06307275

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting
Description: Fasting for 16 hours from participant last meal of the previous evening's meal to the first meal of the next day. Then for 8 hours, participant is able to eat. During the fasting, participants are allowed to consume water and black coffee/tea. Participants will also keep their normal weekly exercise routine.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: non fasting
Description: Participants will not be fasting during these four weeks. They will eat their normal food intake and keep their normal physical activity levels.
Study: NCT04877275

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor (80mg/d)
Description: Selinexor (ATG-010） is a first-in-class, oral selective exportin 1 (XPO1) inhibitor (1,2). Selinexor functions by binding with and inhibiting the nuclear export protein XPO1 (also called CRM1), leading to the accumulation of tumor suppressor proteins in the cell nucleus along with inhibition of translation of oncoprotein mRNAs.~Arm I：80mg/d QW ;

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor (100mg/d)
Description: Selinexor (ATG-010） is a first-in-class, oral selective exportin 1 (XPO1) inhibitor (1,2). Selinexor functions by binding with and inhibiting the nuclear export protein XPO1 (also called CRM1), leading to the accumulation of tumor suppressor proteins in the cell nucleus along with inhibition of translation of oncoprotein mRNAs.~Arm II：100mg/d QW ;

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegylated liposomal doxorubicin
Description: 25 mg/m\^2 intravenously on day 1 , QW

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone 40mg/d QW

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone 40mg/d QW

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Cyclophosphamide：300mg/m2, d1 QW，
Study: NCT05533853

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Posture corrective exercises
Description: The exercises are of two types strengthening exercises and starching exercise ,). The strengthening exercises are to be done for 15 repetitions in 2 sets, Progression will be by increasing to 3 sets and adding 1 Kilogram of resistance in dumbbells exercises, the targeted muscles are teres minor, infraspinatus, medial and lower trapezius, rhomboids, and cervical flexor muscles. On the other hand, stretching exercises are to be hold for 30 seconds for 2 sets then progressed to 3 sets, the targeted muscles are pectoralis minor, sternocleidomastoid and levator scapulae.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Denneroll extension traction
Description: The participants will be instructed to lie supine and keep their legs extended. Based on the apex of each participant's cervical curvature on the initial radiograph, the therapist will position the apex of the denneroll in one of two regions (mid cervical placement or lower cervical placement). The duration of the traction session will start at 2-3 min and increased 1 min per session until reaching the goal of 20 min, the traction will repeated three times per week for 6 weeks
Study: NCT06152991

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GODEX
Description: The amount of active ingredient per dose (1 capsule)~* Carnitine Orotate 150mg~* liver extract antitoxic fraction 12.5㎎~* Adenine Hydrochloride 2.5mg~* Pyridoxine Hydrochloride 25mg~* Riboflavin 0.5mg~* Cyanocobalamin 0.125mg~* Biphenyl Dimethyl Dicarboxylate 25mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: * Anhydrous lactose 50mg.~* Colloidal silicon dioxide 12mg.~* Amorphous cellulose 50mg.~* Lactose monohydrate 215.625mg.~* Magnesium stearate 7mg.~* Upper and lower brown opaque capsules 77mg.
Study: NCT05351346

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: Rituximab IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide
Description: Cyclophosphamide IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Cyclophosphamide IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin
Description: Doxorubicin IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Doxorubicin IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vincristine
Description: Vincristine IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Vincristine IV infusion will be administered as per the schedule specified in the respective arm.
Study: NCT04647097

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard intervention only
Description: Standard intervention (SI) will be a part of standard care in all participating centers, and will be provided for all acute pancreatitis patients, who are hospitalized and their condition is alcohol induced. A specially trained study nurse will deliver the intervention, since they were found to be the most effective regarding the decrease in alcohol consumption and smoking. The cost- effectiveness of the intervention and the feasibility were also taken into account. The Assist-linked brief intervention according to the World Health Organization (WHO) will serve as the base for the intervention, with an avarage of 30 minutes, based on a review containing 69 randomized controlled trials, which concluded that longer intervention do not have additional benefit. The patients will be also educated about the disease course of acute pancreatitis during the standard intervention.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard intervention plus repeated intervention
Description: Standard intervention (SI) will be performed as described above. The repeated intervention will be delivered by the former mentioned same nurse and will be structured similarly to the standard intervention. Every visit and intervention will be individually altered according to the motivation of the patient, but they will follow the same structure. The sessions can be divided into three main parts: first, highlighting the harmful effects of smoking and alcohol on the pancreatic functions. Secondly, a discussion about the motivation of the patient will happen. The last portion of the session will focus on the responsibility of the individual to reach the desired goal will be highlighted. To enhance the efficacy of our intervention we wish to provide feed-back for the patient based on laboratory testing: the mean corpuscular volume (MCV) and gamma glutamyl-transferase (GGT) values will be measured right before the interview. The study nurse will not take part in patient care.
Study: NCT05240365

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SDF modified Hall technique
Description: * Preparation for Hall technique and selection of the crown.~* Clinical application of SDF.~* Cementation of the selected crown.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional pulpotomy and stainless steel crown
Description: * Teeth will be anesthetized .~* Rubber dam will be used and high suction in pulpotomy procedure.~* Cavity outline will be performed by sterile #330 high speed bur using water spray.~* Caries will be removed by large spoon excavator.~* pulpal exposure will be occurred then the roof of pulp chamber will be removed by low speed round bur. Hemostasis will be obtained by applying pressure with moist cotton pellet with saline.~* Teeth will be treated by using sterile cotton pellet with formcresol for three to five min then, remove it.~* Pulp stumps of will be dressed with reinforced zinc oxide eugenol, IRM®\*~* Tooth Preparation will be done followed by placement of stainless-steel crown
Study: NCT04338763

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RP72
Description: RP72 is formulated as a sterile lyophilized powder which is reconstituted in sterile water for injection (WFI) prior to administration. IV injection of RP72 will be administered thrice weekly in the first 28-day treatment cycle (Cycle 1). RP72 will continue to be administered thrice weekly for 4 weeks for Cycle 2 and each subsequent 28-day treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RP72
Description: RP72 is formulated as a sterile lyophilized powder which is reconstituted in sterile water for injection (WFI) prior to administration. IV injection of RP72 will be administered thrice weekly in the first 28-day treatment cycle (Cycle 1). RP72 will continue to be administered thrice weekly for 4 weeks for Cycle 2 and each subsequent 28-day treatment cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine is an anti-cancer chemotherapy drug. IV infusion of Gemcitabine will be administered once weekly in the first 28-day treatment cycle (Cycle 1). Gemcitabine will continue to be administered once weekly for the first 3 weeks and then one week rest in Cycle 2 and each subsequent 28-day treatment cycle.
Study: NCT05490940

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tisseel®
Description: The investigational medical product (IMP) in this study is Tisseel®, which is a tissue sealer consisting of two components:~1. Sealer protein: Human fibrinogen as glue component and synthetic Aprotinin, which delays fibrinolysis.~2. Human thrombin: Thrombin is an unique molecule that functions both as a procoagulant and anticoagulant. It activates platelets through its receptor on the platelets and regulates its own. generation by activating coagulation factors V, VIII and even XI resulting in a burst of thrombin formation.~Its indications are a better hemostasis, enforcement of vessel/gastrointestinal sutures and tissue sutures (mesh grafts, flaps etc).
Study: NCT05945446

Intervention type: DIAGNOSTIC_TEST
Intervention: Galectin 3
Description: Women diagnosed with Placenta Accreta Spectrum (PAS) were invited to join the study, providing they had no known systemic diseases (e.g. chronic hypertension, diabetes, hypothyroidism, chronic renal-liver diseases, etc.), autoimmune disorders, multiple pregnancies, or the presence of fetal structural and chromosomal anomalies. They also did not have cholestasis of pregnancy, preterm delivery, or evidence of chronic and active infection.

Intervention type: DIAGNOSTIC_TEST
Intervention: Galectin 3
Description: Women diagnosed with Placenta Accreta Spectrum (PAS) were invited to join the study, providing they had no known systemic diseases (e.g. chronic hypertension, diabetes, hypothyroidism, chronic renal-liver diseases, etc.), autoimmune disorders, multiple pregnancies, or the presence of fetal structural and chromosomal anomalies. They also did not have cholestasis of pregnancy, preterm delivery, or evidence of chronic and active infection.
Study: NCT04629651

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Captopril
Description: Oral, to be administered per the dose escalation scheme.
Study: NCT05664178

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Resistance Training
Description: Tele-Resistance training sessions will be supervised and guided by a certified exercise trainer via smartphone, tablet or laptop. Exercises will be performed using resistance tubes (Bodylastics Resistance Bands Set) and a connectable bar (Bionic Body Workout Bar) that mimics a weighted barbell when tubes are attached. The tubes provide up to 142 pounds of resistance (adjustable in increments between 3-10 pounds) when simultaneously connected to handles or bar, and multiple tubes can be attached simultaneously. Participants will engage in brief warm up exercises lasting 2-3 minutes prior to each RT session and will rest at least 1 minute between sets of the same exercise to aid muscle recovery. Participants will perform at least 2 sets of 12 repetitions for each of 6 exercises. Including warm up, training sets, and rest, sessions will last approximately 30 minutes. RT will include six target exercises focusing on major muscle groups of the upper body, lower body, and core.
Study: NCT04889989

Intervention type: DEVICE
Group type: OTHER
Intervention: Microwave Ablation
Description: Percutaneous microwave ablation using the NeuWave Microwave Ablation System for non-small cell lung cancer or oligometastatic lung tumors
Study: NCT05977192

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard MI
Description: One phone-based MI session

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive MI
Description: Four phone-based MI sessions

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MOTIVACC
Description: mHealth-based MI

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ecological momentary assessment (EMA) messages
Description: EMA messages focused on vaccinations and health

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ecological momentary assessment (EMA) messages
Description: EMA messages focused on vaccinations and health

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ecological momentary assessment (EMA) messages
Description: EMA messages focused on vaccinations and health
Study: NCT05442801

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclopentolate
Description: Well known eye drop used for cycloplegic refraction among children.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tropicamide
Description: Well known eye drop used for cycloplegic refraction among children.
Study: NCT05675098

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate
Description: This medication is a psychostimulant medication and is usually prescribed for individuals with Attention-Deficit/Hyperactivity Disorder to manage ADHD behavioral symptoms

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modafinil
Description: This medication is a Central Nervous System stimulant and is usually used to treat neurological conditions, including Narcolepsy

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participant will receive placebo tablets (Methylphenidate and Modafinil shape)
Study: NCT05581108

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Juice PLUS+® OMEGA
Description: Daily dose of total Omega blend: 925 mg (2 capsules)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: matched placebo (2 capsules)
Study: NCT05908136

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: restorative materials
Description: two types of composite with strip crown in primary molars

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: restorative materials
Description: two types of composite with strip crown in primary molars

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: restorative materials
Description: two types of composite with strip crown in primary molars
Study: NCT06420752

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Calf Plantar flexion
Description: Daily passive calf stretching

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Calf Plantar flexion
Description: Daily passive calf stretching

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary nitrate
Description: Weekday 140 ml dietary nitrate consumption two hours prior to passive stretching

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary nitrate
Description: Weekday 140 ml dietary nitrate consumption two hours prior to passive stretching
Study: NCT05310292

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Oral glucose tolerance test
Description: Consumption of 75 grams of glucose, diluted in water, added 1,5 g of acetaminophen.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Oral glucose tolerance test
Description: Consumption of 75 grams of glucose, diluted in water, added 1,5 g of acetaminophen.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mixed meal test
Description: Consumption of a standardized liquid meal, with caloric and dietary content equal to a standard meal.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mixed meal test
Description: Consumption of a standardized liquid meal, with caloric and dietary content equal to a standard meal.
Study: NCT06299345

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor imagery training
Description: MI for this study took the form of non-guided first-person mental practice. First-person imagery was explained to each participant where they imagined performing the target skill through their own eyes rather than if they were a bystander watching someone else do the task (third person).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor imagery training
Description: MI for this study took the form of non-guided first-person mental practice. First-person imagery was explained to each participant where they imagined performing the target skill through their own eyes rather than if they were a bystander watching someone else do the task (third person).

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: NO motor imagery training
Description: The participants performed the physical task only. It is a mirror tracing game that requires participants to trace a star shape viewed through a mirror, going as fast as possible while staying within the lines.
Study: NCT04823156

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Calcium
Description: Daily calcium food supplement.
Study: NCT06518811

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video-Based Exercise Programme
Description: The asynchronous video-based telerehabilitation programme had a duration of eight weeks. The participants were instructed to perform the exercises on a regular basis, three days a week, with a time interval of 24 hours between each session. The exercises were to be performed using the instructional videos and recorded in the exercise diaries provided. The participants were used exercise balls and resistance bands distributed by the researchers according to exercise programme.