TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05700591

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rhPro-UK
Description: 35 mg, administered intravenously with a bolus of 15 mg within 3 minutes and the remainder by continuous infusion within 30 minutes

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: rt-PA
Description: 0.9 mg/kg (maximum 90 mg), with 10% administered intravenously as a bolus, followed by 90% infusion within 1 hour
Study: NCT06132646

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Proprioceptive exercises
Description: Specific proprioceptive exercises for the wrist that the patient has to do currently with standard rehabilitation.
Study: NCT05836077

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education with pecha kucha method
Description: Education with pecha kucha method
Study: NCT05658887

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gabapentin
Description: One dose of preoperative gabapentin 300 mg prior to vaginal apical support procedure

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Gabapentin Placebo
Description: Gabapentin Placebo
Study: NCT05567380

Intervention type: OTHER
Intervention: Observation
Description: Observation of Rheumatoid arthritis disease response to JAK inhibitors and TNF inhibitors after definite timepoints from the initialization of treatment in comparison to the current standard of care of therapy with conventional DMARDs.

Intervention type: OTHER
Intervention: Observation
Description: Observation of Rheumatoid arthritis disease response to JAK inhibitors and TNF inhibitors after definite timepoints from the initialization of treatment in comparison to the current standard of care of therapy with conventional DMARDs.

Intervention type: OTHER
Intervention: Observation
Description: Observation of Rheumatoid arthritis disease response to JAK inhibitors and TNF inhibitors after definite timepoints from the initialization of treatment in comparison to the current standard of care of therapy with conventional DMARDs.
Study: NCT05346055

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Engage Prism (2.0)
Description: Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Study: NCT06007391

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotinamide
Description: nicotinamide 3g per day
Study: NCT05071807

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pecans
Description: Participants will receive 2 oz of pecans daily to replace a typical snack and continue consuming their usual diet for 12 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants will receive grocery vouchers and continue consuming their usual diet for 12 weeks.
Study: NCT06062420

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nelistotug
Description: Nelistotug will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK4381562
Description: GSK4381562 will be administered.
Study: NCT05627609

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 311 nm narrowband UVB irradiation
Description: Participants will be irradiated with 311nm UVB for 5 days per week and 4 weeks in total.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 311 nm narrowband UVB irradiation
Description: Participants will be irradiated with 311nm UVB for 5 days per week and 4 weeks in total.
Study: NCT05993338

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: right heart catheterization (RHC).
Description: Assessment of pulmonary artery pressure in COVID-19 survivors using right heart catheterization (RHC).
Study: NCT06109103

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: telerehabilitation-based motor imagery training
Description: Motor imagery is defined as the mental thinking of a movement without actual movement being revealed. Many of the currently available physiotherapy and rehabilitation approaches are designed to stimulate damaged motor neural connections through neuroplasticity.~based on real movements. Studies have shown that similar brain regions are activated during motor imagery and real movement. By repeatedly visualizing the same movement, people can improve their motor activity skills such as lifting weights, playing the piano or performing surgery. These findings suggest that motor imagery provides motor learning by strengthening synaptic connections depending on activity.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: telerehabilitation-based physiotheraphy training
Description: The telerehabilitation application will be carried out by video conference method, one of the image-based telerehabilitation technologies. The telerehabilitation-based physiotherapy program will be administered to both Group 1 and Group 2 children by a physiotherapist experienced in the physiotherapy of neuromuscular diseases, excluding the researchers who performed the randomization and evaluations.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: telerehabilitation-based physiotheraphy training
Description: The telerehabilitation application will be carried out by video conference method, one of the image-based telerehabilitation technologies. The telerehabilitation-based physiotherapy program will be administered to both Group 1 and Group 2 children by a physiotherapist experienced in the physiotherapy of neuromuscular diseases, excluding the researchers who performed the randomization and evaluations.
Study: NCT05129579

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Stress Reduction Intervention
Description: Mindfulness Based Stress Reduction intervention is a manualized course that includes meditation, relaxing movement, and breathing. A certified MBSR instructor will teach the courses in a group-based format for 90 minute sessions, once per week for eight weeks.

Intervention type: OTHER
Group type: OTHER
Intervention: no intervention
Description: No intervention will be made in the control group.
Study: NCT06702631

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitrous oxide
Description: After a no-drug control period, subjects will inhale nitrous oxide, administered via a breathing circuit and face mask, until a steady-state target end-tidal expired concentration is reached. During the drug condition, subjects will receive low-dose nitrous oxide (% corresponding to Minimum Alveolar Concentration).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Peripheral Nerve Stimulation
Description: Experimental acute pain stimulus will be delivered using a nerve stimulator. These painful shocks will be paired with a fixed number of the experimental cues, in a pattern that appears random to participants.
Study: NCT06705725

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBG002 CAR-T Cell Suspension
Description: Single dose of CAR+ T cells will be infused, and classic 3+3 dose escalation will be applied.
Study: NCT06705309

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-Based Education
Description: The Effect of a Web-Based Education Program and Educational Booklet Developed on Cervıcal Cancer on Women's Prevention Methods
Study: NCT06705244

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Trans-nasal sphenopalatine nerve block
Description: The patient was placed supine with shoulders slightly elevated to flex the neck and extend the head.~Then anterior nares were inspected for polyps, tumors, or significant septal deviation.~Long cotton-tipped applicators saturated with lidocaine 2% were inserted into each naris, until properly seated in the posterior nasopharynx.~These were left in place for 10 minutes to lubricate and anesthetize the mucous membrane, making the procedure more comfortable.~Then a mixture of 3 mL of 2 mL lidocaine 2% plus 1 mL dexamethasone 4 mg were injected through the applicators in the sphenopalatine area in each nostril.~Then the patient was positioned sitting and pain assessments were recorded.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Greater and lesser occipital nerve block
Description: The back of the head was sterilized with an antiseptic solution and the landmarks at the base of the skull were identified while the patient in the prone position.~The landmarks were located on the medial third of a line drawn from occipital protuberance to mastoid process. At this level, the greater and lesser occipital nerves lie along the superior nuchal line medial to the occipital artery, halfway between the occipital protuberance and mastoid process.~Under Ultrasound guidance, the skin was infiltrated with 1-2 mL of lidocaine 2%, using a 25-gauge needle. Then the block was performed in this area with a mixture of 3 mL of 2 mL lidocaine 2% plus 1 mL dexamethasone 4 mg to block greater and lesser occipital nerves. Then the procedure was repeated on the other side.~After the procedure, the presence of bilateral occipital numbness was confirmed after 30 minutes. The patient was then positioned sitting and pain scoring was assessed.
Study: NCT05016479

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Accelerated repetitive Transcranial Magnetic Stimulation
Description: arTMS is a non-invasive brain stimulation technique. It will be used a MagPro R30 with a Cool-B80 figure-of-eight coil (MagVenture, Falun, Denmark).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Accelerated repetitive Transcranial Magnetic Stimulation
Description: arTMS is a non-invasive brain stimulation technique. It will be used a MagPro R30 with a Cool-B80 figure-of-eight coil (MagVenture, Falun, Denmark).
Study: NCT04864522

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLAMF7 FPBMC
Description: Participants will receive 8 weekly infusions of SLAMF7 FPBMC, then 8 additional infusions every 2 weeks.
Study: NCT06378021

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium Chloride
Description: 5 % calcium chloride injection in cardiac ganglionic Plexus during On pump Coronary artery bypass graft

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sodium Chloride 0.9% Inj
Description: 0.9% sodium chloride injection during on pump during Coronary artery bypass graft
Study: NCT04456023

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tisagenlecleucel
Description: A single intravenous (i.v.) infusion of 0.6 - 6.0×10\^8 CAR positive viable T cells.
Study: NCT05317104

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: For 6 weeks, 3 times a week, aerobic exercise will be performed with a treadmill at 55-74% of the maximal heart rate.
Study: NCT04892498

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated radiotherapy
Description: 10-24Gy/5-8Gy/2-3f

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 inhibitor
Description: q3w, until PD

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GM-CSF
Description: 200μg, D1-D7, ≥8 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IL-2
Description: at a dose of 2 million IU, D8-D14, ≥8 cycles
Study: NCT05687058

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 25 mg thrice-weekly post-hemodialysis dosing
Description: Participants in Group I will be asked to take empagliflozin 25 mg after each hemodialysis session under direct observation by a trained health care worker.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 10 mg daily dosing
Description: Participants assigned to Group II will be asked to take empagliflozin 10 mg each morning between 8:30 and 9:30 a.m. at home.
Study: NCT05298722

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Imaging analysis of CT-scan and MRI with radiomics and genetic analysis of peripheral blood samples and questionnaires.
Description: * The images of CT-scans and MRI with DWI shall be processed with specific software to define the direction of diffusion tensors and indicate the direction (red, green, blue coloring for x,y,z, components of the vector) and intensity (anisotropy, brightness of voxels). Further analysis will be performed by fiber tracking which gives a clear indication of functional connectivity of adjacent tissues.~* Genetic profilling of liquid biopsies: evolution of the number CTCs in blood samples of patients and subsequent phenotyping of the cells; longitudinal analysis of driver mutations and epigenetic changes in cfDNA; genotyping of germline variations~* Questionnaires for patient reported outcomes and health economic analysis~  * EQ-5D-5L~ * PAN 26~ * HADS
Study: NCT06357481

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endodontic Retreatment
Description: A single operator procedured in one visit of non-surgical endodontic retreatment. Teeth were anesthetized using articaine hydrochloride with epinephrine 1:200,000 for mandibulary premolar teeth with one root canal. Each tooth was isolated with a rubber dam and then coronal restorations and caries were removed using sterile high-speed burs under water cooling. After preperation of the cavity access and localization of the canal orifice, all microorganisms that may have entered the root canal system are eliminated by removing the old canal filling with the One Flare and MicroMega REMOVER files in the MicroMega retreatment kit.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endodontic Retreatment
Description: A single operator procedured in one visit of non-surgical endodontic retreatment. Teeth were anesthetized using articaine hydrochloride with epinephrine 1:200,000 for mandibulary premolar teeth with one root canal. Each tooth was isolated with a rubber dam and then coronal restorations and caries were removed using sterile high-speed burs under water cooling. After preperation of the cavity access and localization of the canal orifice, all microorganisms that may have entered the root canal system are eliminated by removing the old canal filling with the One Flare and MicroMega REMOVER files in the MicroMega retreatment kit.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endodontic Retreatment
Description: A single operator procedured in one visit of non-surgical endodontic retreatment. Teeth were anesthetized using articaine hydrochloride with epinephrine 1:200,000 for mandibulary premolar teeth with one root canal. Each tooth was isolated with a rubber dam and then coronal restorations and caries were removed using sterile high-speed burs under water cooling. After preperation of the cavity access and localization of the canal orifice, all microorganisms that may have entered the root canal system are eliminated by removing the old canal filling with the One Flare and MicroMega REMOVER files in the MicroMega retreatment kit.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endodontic Retreatment
Description: A single operator procedured in one visit of non-surgical endodontic retreatment. Teeth were anesthetized using articaine hydrochloride with epinephrine 1:200,000 for mandibulary premolar teeth with one root canal. Each tooth was isolated with a rubber dam and then coronal restorations and caries were removed using sterile high-speed burs under water cooling. After preperation of the cavity access and localization of the canal orifice, all microorganisms that may have entered the root canal system are eliminated by removing the old canal filling with the One Flare and MicroMega REMOVER files in the MicroMega retreatment kit.
Study: NCT04829136

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Kate Farms 1.0
Description: Given enteral nutrition via nasoenteric feeding

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Nutritional Support
Description: Given standard of care, which may be parenteral nutrition

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary Supplement
Description: Receive fiber supplementation orally or enterally

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood and stool samples

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fiber and Dietary Assessments
Description: Ancillary studies
Study: NCT06417528

Intervention type: PROCEDURE
Intervention: Chronic Post Surgery Pain (CPSP)
Description: The outcome variable is the presence of CPSP assessed 3 months after surgery and defined as an average pain intensity of at least 3 on the NRS scale (11-point one-dimensional pain scale) in the last three days, and pain localized to the surgical field (or in the lesion area) projected into the innervation territory of a nerve located in this area or referred to a dermatome.~Separate prediction models will be developed using data derived from surveys conducted at the relevant time points for the development of the risk index.
Study: NCT06474195

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cue based intervention
Description: The intervention arm will receive the cues in the form of daily repeating reminders for a time period of 30 days. The reminders will be set on participants' mobile phones to receive at least 1 hour prior to the prescribed oral antipsychotic medication. The same reminder will be repeated after 10 minutes duration to ensure that the participant does not miss the cue and the uniformity of the cue will be ensured by setting the same emoji or the same phrase on the participant's own mobile phone. The participant will also be asked a task of daily routine during the same time of medication.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual
Description: This group will not get any intervention but the usual treatment all assessments will continue
Study: NCT04732520

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed electric field treatment using the Aliya System
Description: pulsed electric field treatment of a single NSCLC tumor
Study: NCT06043024

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Stabilization occlusal splint
Description: Patients will be treated with a stabilizing occlusal splint made of hard acrylate resin, about 1.5 mm thick in the posterior teeth area with an incisal plateau for canine guidance. OS will be made by the same dental technician in the dental laboratory.
Study: NCT06552273

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Reasoning bias correction training
Description: Emotional Reasoning Bias correction training involves 12 daily self-applied sessions focusing on psychoeducation about emotions and identifying ER biases and their impact on behaviour.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module of Mindfulness of the Transdiagnostic treatment
Description: Module based on mindfulness using techniques for training in awareness and acceptance of experiences, observing experiences as they arise without judgment.
Study: NCT05551299

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Photosensitizer
Description: A photosensitizer, which is absorbed preferentially by tumour cells, is administered 24 - 48 hours prior to PDT. Light of a particular wavelength is then applied during endoscopic retrograde cholangiopancreatography (ERCP) to kill primarily cancer cells locally within the stenosis. Immediately after PDT treatment, new stents are inserted into all treated segments if needed.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation (RFA)
Description: RFA is also carried out as part of an ERCP. The RFA-probe is placed within the tumour stenosis and electrical current is applied. New stents are inserted into all treated segments if needed.
Study: NCT06335641

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: External active conductive head cooling
Description: Cooling is applied during the endovascular thrombectomy procedure for a maximum of 120 minutes
Study: NCT06425861

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THB335 single dose
Description: Single dose as oral capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Single dose placebo
Description: Single dose as oral capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THB335 fasted/fed
Description: Single dose fasted and fed as oral capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo fasted/fed
Description: Single dose fasted and fed as oral capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THB335 multiple dose
Description: Multiple ascending doses oral capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Multiple dose placebo
Description: Multiple doses oral capsule
Study: NCT06211920

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-invasive ventilation
Description: The application of NIV will be performed using af a facemask as soon as possible after the patient has been randomized by opening the opaque envelope. All patients will receive the same standardized ventilator settings at initiation. The IPAP will be set at 12 cm H2O and the PEEP at 5 cm H2O. Oxygen delivery will be adjusted to an arterial oxygen saturation of 88-92%. Further adjustment of ventilator settings and evaluation of treatment effect will be at the discretion of the prehospital physician.
Study: NCT04962776

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Low-concentration carbohydrate and nitrates
Description: Patients in the CHON group will be given 400 mL of a clear carbohydrate drink (12.5 g/100 mL maltodextrin, 50 kcal/100 mL) and 2 capsules of beet root extract 1 gm on the evening before surgery (8 hours) and another 200 mL of the carbohydrate drink and 1 capsule of beet root extract 1 gm on the day of surgery, 2 h before anesthesia induction.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Low-concentration carbohydrate
Description: Patients in the CHO group will be given the same carbohydrate drink in the CHON group with 2 placebo capsules with the evening drink and one with the morning drink.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Water with placebo capsules
Description: Patients in the W group will be given equivalent volume of drinking water with placebo capsules by evening and in the morning of surgery.
Study: NCT05183061

Intervention type: DRUG
Intervention: Ehedrine Norepineprine
Description: No interventions required considering that this was a retrospective study.