TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06428513

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HCTP
Description: 10 weekly 1-on-1 30-minute tele-sessions via Zoom, delivered by a certified health coach. At baseline assessment including full medical history, medications, lifestyle practices, self-reported health status, psychosocial status, and other relevant information will be taken. At the first session, participants identify their health vision and 3-month health goals. At subsequent meetings, participants review their progress towards reaching the prior week's goals and identify goals for the next week. An individualized action plan will be formulated to help each participant achieve their goals. The action plan will focus on important lifestyle practices (physical activity/exercise training, correct nutrition, weight management, tobacco cessation, and stress management. Patients can request further health care advice felt necessary for their progress, and will be referred to health care professionals in the rehabilitation hospital that provide care for lung transplantation candidates.
Study: NCT04376359

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hyperbaric oxygen therapy
Description: Hyperbaric oxygen therapy is the patient put in airtight oxygen tank, by increasing the air pressure in the environment (1.5 to 3.0) under atmospheric pressure, to give 100% oxygen, the patient treatment time is approximately 60 minutes to 120 minutes in this way, can achieve the purpose of greatly increase the oxygen partial pressure in the organization, so as to achieve reverse brain edema, reduce lipid peroxidation, inhibiting leukocyte hyperactivity, rebuild the blood brain barrier.
Study: NCT04846647

Intervention type: BEHAVIORAL
Intervention: unexplained hypophoshatemia
Description: Collection of additional blood volume (approximately 10 mL) during blood tests provided as part of the usual medical care.
Study: NCT06602492

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lower nicotine e-liquid
Description: A 3% nicotine concentration eliquid.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Higher nicotine eliquid
Description: A 5% nicotine concentration eliquid.
Study: NCT05921006

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral，tablets，Once daily daily for 14 days
Study: NCT06605625

Intervention type: BIOLOGICAL
Intervention: Influenza vaccination
Description: one annual dose of inactivated influenza vaccine

Intervention type: BIOLOGICAL
Intervention: SARS-CoV-2 vaccine
Description: dose of SARS CoV2 vaccine

Intervention type: BIOLOGICAL
Intervention: Zoster Vaccine Recombinant
Description: first and/or second vaccination for shingles (Herpes zoster)
Study: NCT06260891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 25 mg/day zinc
Description: 25 mg of zinc as zinc gluconate taken orally once a day
Study: NCT04622293

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A placebo encapsulated to look the same as the experimental drug will be given to the control group.
Study: NCT06260891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 40 mg/day zinc
Description: 40 mg of zinc as zinc gluconate taken orally once a day
Study: NCT05244304

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tinlarebant
Description: Tinlarebant drug substance is a white to off-white substance and is dispensed as a tablet for oral administration.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Not active drug
Study: NCT05412095

Intervention type: OTHER
Intervention: Ultrasound of the abdominal wall muscles
Description: the measurements will be performed during inspiration and expiration to take into account variability during the respiratory cycle. The examination is performed bilaterally and comparatively and lasts between 3 and 5 minutes.

Intervention type: OTHER
Intervention: Ultrasound of the abdominal wall muscles
Description: the measurements will be performed during inspiration and expiration to take into account variability during the respiratory cycle. The examination is performed bilaterally and comparatively and lasts between 3 and 5 minutes.

Intervention type: OTHER
Intervention: Ultrasound quadricipital
Description: The examination is performed bilaterally and comparatively and takes between 3 and 5 minutes.

Intervention type: OTHER
Intervention: Ultrasound quadricipital
Description: The examination is performed bilaterally and comparatively and takes between 3 and 5 minutes.

Intervention type: OTHER
Intervention: Ultrasound of the diaphragm
Description: The examination is performed bilaterally and comparatively and takes between 5 and 10 minutes.
Study: NCT06615908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: See treatment arm description.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: See treatment arm description.
Study: NCT06616727

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNC109
Description: SNC-109 CAR-T Cells, first dose from 5×104 CAR+ T Cells, treatment follows the operation and the next dose would be deiced by SRC
Study: NCT06553625

Intervention type: DEVICE
Intervention: Radiofrequency Ablation
Description: Radiofrequency Ablation used in the central nervous system (CNS) in functional neurosurgery
Study: NCT05277155

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: BEJO Red Ginger Extract
Description: BEJO Red Ginger Extract ingredients:~* Zingiber officinale var. rubrum (Rhizome extract) 80 mg~* Foeniculi vulgare Fructus (Fennel) 25 mg~* Menthae arvensis Folium (Mint) 5 mg~* Piper retrofractum Fructus (Javanese long pepper) 12.5 mg~* Honey 7500 mg

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo composition: Substance without active ingredient
Study: NCT06215898

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LSVT-BIG Group via Telerehabilitation
Description: An aerobic supervised exercise protocol was implemented four times a week for four weeks in LSVT-BIG Group via a Tele-rehabilitation model.
Study: NCT04746612

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HH30134
Description: HH30134 administered orally on a continuous once daily(QD) in patients with advanced solid tumors
Study: NCT06674135

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: biosimilar insulin glargine
Description: Switched to once daily injection of biosimilar insulin glargine via reusable pen and three mealtime bolus insulin injections of short-acting human insulin via needle and syringe
Study: NCT06616467

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tummy Time for the prevention of childhood obesity
Description: A cognitive-behavioral intervention aimed at mothers of infants is presented that aims to increase the practice of TT and maintain a healthy weight in the infant, called \&#34;Tummy Time for the prevention of childhood obesity\&#34;, within the intervention modifiable variables are involved that directly impact the expected results such as: the knowledge and beliefs of the mothers, infant temperament, parental self-efficacy and self-efficacy for the practice of TT.~The intervention lasts 12 weeks from the first contact with the participants and consists of eight sessions broken down as follows: the first session is presented in a face-to-face format with expository, audiovisual and demonstrative means; sessions two, four, five and seven are provided through a text message with use WhatsApp® and the use of visual media. Sessions three, six and eight are delivered via telephone call with the aim of offering feedback on the doubts generated up to that point.
Study: NCT06677931

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator:1565 non-ablative fractional laser combined with normal Saline
Description: Based on the patient's age, skin color, location of skin lesions, and Fitzpatrick skin type, adjust treatment parameters accordingly. The operator holds the treatment head, vertically applies parallel sweeps closely to the lesion area until the endpoint of slight skin redness is reached. After completion, apply normal Saline.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 1565 non-ablative fractional laser combined with umbilical cord mesenchymal stem cell-derived exosomes.
Description: Based on the patient's age, skin color, location of skin lesions, and Fitzpatrick skin type, adjust treatment parameters accordingly. The operator holds the treatment head, vertically applies parallel sweeps closely to the lesion area until the endpoint of slight skin redness is reached. After completion, apply exosomes.
Study: NCT06677788

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Roflumilast 500 Mcg Oral Tablet
Description: Patients in this group received roflumilast 500 μg once daily for three months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin E capsule
Description: vitamin E group or control group (n=24) which received vitamin E 1000 mg once daily
Study: NCT05135624

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SP16 (6mg)
Description: SP16 will be administered as 2 concurrent, separate 2 mL s.c injections of 3mg/mL SP16

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered as 2 concurrent, separate 2 mL s.c. injections of sterile water
Study: NCT05412095

Intervention type: OTHER
Intervention: Ultrasound of the diaphragm
Description: The examination is performed bilaterally and comparatively and takes between 5 and 10 minutes.

Intervention type: OTHER
Intervention: Ultrasound of the inter-costal muscles
Description: measurements performed bilaterally on a patient in a half-sitting position at 45° and in spontaneous ventilation

Intervention type: OTHER
Intervention: Ultrasound of the inter-costal muscles
Description: measurements performed bilaterally on a patient in a half-sitting position at 45° and in spontaneous ventilation

Intervention type: OTHER
Intervention: Ultrasound of the inter-costal muscles
Description: In spontaneous ventilation, lying down, arms by the side of the body, palms up, head down

Intervention type: OTHER
Intervention: Ultrasound of the inter-costal muscles
Description: In spontaneous ventilation, lying down, arms by the side of the body, palms up, head down
Study: NCT05072704

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sufentanil
Description: Pre-operative injection of sufentanil 10µg in 2ml of normal saline on induction of anesthesia + per-operative injection of sufentanil 5µg in 1ml of normal saline during the surgery if needed.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Pre-operative infusion of dexmedetomidine 1µg/kg in 100ml of normal saline before surgery + per-operative infusion of dexmedetomidine 0.4 µg/kg in 100ml of normal saline during the surgery if needed.
Study: NCT04442113

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary vein isolation plus ablation guided by novel STAR mapping™
Description: Catheter ablation for persistent AF consisting of pulmonary vein isolation plus additional ablation guided by the novel STAR mapping™ software on a computer device.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary vein isolation
Description: Catheter ablation for persistent AF consisting of pulmonary vein isolation (the standard treatment for AF)
Study: NCT05802212

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin intervention for 12 weeks
Description: PCOS patients were treated with metformin orally for 12 weeks, and various indicators related to fertility were observed.
Study: NCT05886504

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Community-based psychiatric intervention
Description: intervention will take place in CBO offices instead of mental health department, medication will be given freely and psychiatric consultations will be free. Trained CBO members will provide individual and collective support including recall of appointments and tracing of those lost to follow-up, information on mental health, main psychiatric disorders, psychiatric medication, their potential side effects and expected benefits, contact with families and continuous support
Study: NCT06681818

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: carbon monoxide measurement via smokerlyzer
Description: participants in this study will provide breath samples for carbon monoxide measurements pre and post liver resection
Study: NCT05412875

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Given usual care

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Replacement
Description: Given JUUL

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT04980157

Intervention type: BEHAVIORAL
Intervention: CARES-HCV
Description: CARES-HCV is an educational intervention to promote both hepatitis c screening and colorectal cancer screening among diverse baby boomers in the area.
Study: NCT06465966

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iRAI
Description: Ionizing-radiation photo acoustic imaging (iRAI) is a method of collecting images from inside the body using acoustic (sound) waves. Researchers will collect iRAI during a participant's radiation treatments. Researchers will use this imaging to examine the delivery and dose of the radiation to the participant's prostate. Researchers will also compare the delivery and dose calculated from iRAI to the expected doses that were calculated from CT images which are done as standard of care.
Study: NCT06000787

Intervention type: RADIATION
Group type: OTHER
Intervention: External beam radiotherapy
Description: Subjects with diffuse midline glioma on PNOC023 (NCT04732065) Arm A or B receive standard-of-care external beam radiotherapy to the brain tumor.
Study: NCT05412875

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05938842

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online DBT-Mindfulness Intervention
Description: The whole intervention exists of 10 sessions, one session a week for at least one hour and a half. The session 1 is tailored to address specific issues to people with MS, whereas the sessions 2 to 7 are based on DBT and mindfulness contents, and in sessions 7 to 10 introduced some contents of ACT. The program is based in teaching two different sets what and how (Linehan, 1993). The first skill what, teaches patients to simply observe; in a second level, to describe, which implies the ability to put the name to what one has observed; and in the third, what skill patients learn to fully participate in their actions in the current moment and without self-consciousness (Soler et al., 2012). In the other hand, the skills of how are related to how observe, how to describe and how to participate. Moreover, some mindfulness skills such as Observing the breath, Half-smiling, Awareness are practice introduced as homework tasks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online psychoeducational intervention
Description: The active control group intervention will be based on a psycho-educational framework and will involve MS-related topics (Oz \& Oz, 2020). The psychoeducational intervention will be conducted by a psychologist with experience in working with pwMS through group videoconference and will follow similar format as the DBT-Mindfulness intervention, except for the homework tasks. The participants will receive information about different aspects related to the disease (e.g., disease progression, disease-symptoms, stress management, nutrition, sleep hygiene, physical activity, social relationships). The content of the sessions of the psychoeducation program was created based on the current literature about MS. Similar psychoeducational programs were used in other studies before (Oz \& Oz, 2020; Dowd et al., 2015).
Study: NCT06204978

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: short-chain fructo-oligosaccharides (dose 1)
Description: 10 g / day at breakfast during 7 days (Day 8 - Day 14)

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: short-chain fructo-oligosaccharides (dose 2)
Description: 20 g / day at breakfast during 7 days (Day 8 - Day 14)

Intervention type: OTHER
Group type: OTHER
Intervention: Baseline
Description: 0 g / day of short-chain fructo-oligosaccharides during 7 days (Day 1 - Day 7)
Study: NCT05135624

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SP16 (12 mg)
Description: SP16 will be administered as a single 2 mL s.c. injection of 3 mg/mL SP16 and 1 concurrent separate 2 mL s.c. injection of sterile water
Study: NCT06204978

Intervention type: OTHER
Group type: OTHER
Intervention: Baseline
Description: 0 g / day of short-chain fructo-oligosaccharides during 7 days (Day 1 - Day 7)
Study: NCT06214416

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Abstention
Description: All the intervention will be carried out online once a month for a year, focusing on nutritional, behavioral and scientific evidence aspects, that promote abstention.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mediterranean alcohol-drinking pattern
Description: All the intervention will be carried out online once a month for a year, focusing on nutritional, behavioral and scientific evidence aspects, that promote the Mediterranean alcohol-drinking pattern.
Study: NCT05015439

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol
Description: The study intervention will be supplied as a softgel capsule containing cannabidiol.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The study intervention will be supplied as a softgel capsule containing inert filler.
Study: NCT06215807

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Femtosecond laser arcuate keratotomy
Description: The patient will receive femtosecond laser arcuate keratotomy and femtosecond laser-assisted cataract surgery with implantation of a monofocal intraocular lens in one eye.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Toric intraocular lens implantation
Description: The patient will receive femtosecond laser-assisted cataract surgery with implantation of a Toric monofocal intraocular lens in the contralateral eye.
Study: NCT05932966

Intervention type: DEVICE
Intervention: Insulin closed-loop delivery system
Description: Insulin closed-loop delivery system

Intervention type: DEVICE
Intervention: Insulin closed-loop delivery system
Description: Insulin closed-loop delivery system
Study: NCT05232045

Intervention type: DRUG
Intervention: Automated urinary output collection system group (tight monitoring of urine output)
Description: Automated urinary output collection system group (tight monitoring of urine output)
Study: NCT05565131

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Guided placement with PYTHEAS® ODYSSEE
Description: Pre-surgery, the surgeon generates a 3D model of the spine from a preoperative CT scan During the perforation and insertion of the implant, the system indicates the orientation of the pedicle path and the current orientation of the instruments (perforation tool) with the orientation sensor (inertial sensor). The system also displays the position of the entry point of the planned pedicle path on the views.
Study: NCT04687384

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Robotic-assisted colectomy
Description: Robotic-assisted colectomy performed by usage of da Vinci Xi robotic technology

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional laparoscopic colectomy
Description: Conventional laparoscopic colectomy
Study: NCT06255184

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sernity intervention
Description: Serenity Therapy is a holistic intervention that boosts psychological well-being and emotional balance through relaxation techniques, mindfulness, and guided imagery
Study: NCT05657925

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ondansetron 8 mg
Description: Ondansetron 8 mg prn sublingually when awakening with nausea. as per the FDA label for ondansetron.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching placebo
Description: Matching placebo will be identical in appearance to the active treatment pill
Study: NCT06000787

Intervention type: RADIATION
Group type: OTHER
Intervention: 131I-Metaiodobenzylguanidine (MIBG)
Description: Subjects with high-risk neuroblastoma on COG ANBL1531 (NCT03126916) Arm B receive the radiopharmaceutical 131I-Metaiodobenzylguanidine (MIBG) 15 mCi/kg via either a central or a peripheral IV catheter over 1.5 to 2 hours at a maximum rate of 500 mCi/hour.
Study: NCT05504473

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NEURO-BLINK Device
Description: The NEURO-BLINK is a class IIa medical device that intends to restore the blink function in patients with facial palsy through the application of transcutaneous electrical stimulation.
Study: NCT05688449

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine-fentanyl
Description: A 20 ml bolus of 2 mcg/ml fentanyl + 0.125% bupivacaine solution will be administered to the bupivacaine group via the epidural catheter, and 5ml/hour infusion will be started.
Study: NCT06433037

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Chicory inulin
Description: Chicory inulin (12g/day) divided over two dosages (6g per dose)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Resistant dextrin
Description: Resistant dextrin (14g/day) divided over two dosages (7g per dose)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Seaweed polysaccharide
Description: Seaweed polysaccharide (1g/day) divided over two dosages (0.5g per dose). Additionally contains 7g/day of placebo as a volumetric and isocaloric filler.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Maltodextrin (7g/day) will be provided in two divided doses (3.5g per dose)