TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04577573

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cognition glove
Description: The investigators have developed and tested a functional prototype of an instrumented glove to alert the user about secure grasp of objects. Onboard force and flex sensors provide inputs to a machine learning algorithm (artificial neural network, ANN) to estimate secure grasp based on previously collected training data. The glove enhances agency by alerting the user to secure grasp through sensory feedback modules (visual - LED, audio - beeper, tactile - vibrator).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cognition glove
Description: The investigators have developed and tested a functional prototype of an instrumented glove to alert the user about secure grasp of objects. Onboard force and flex sensors provide inputs to a machine learning algorithm (artificial neural network, ANN) to estimate secure grasp based on previously collected training data. The glove enhances agency by alerting the user to secure grasp through sensory feedback modules (visual - LED, audio - beeper, tactile - vibrator).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cognition glove
Description: The investigators have developed and tested a functional prototype of an instrumented glove to alert the user about secure grasp of objects. Onboard force and flex sensors provide inputs to a machine learning algorithm (artificial neural network, ANN) to estimate secure grasp based on previously collected training data. The glove enhances agency by alerting the user to secure grasp through sensory feedback modules (visual - LED, audio - beeper, tactile - vibrator).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sensory brace
Description: A a size- and position-adjustable arm brace with weight-support capability and housing for vibration motors and EMG sensors. Position adjustment allows for physical therapists to find and recommend arm postures that are clinically relevant to~each person. The participant can then isometrically push/resist against the brace to strengthen target muscles while performing VR reach-to-touch. The person will receive visual feedback from the virtual environment to train movement performance and vibrotactile feedback at tendons to subconsciously adjust their muscle activation patterns
Study: NCT05481684

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal Progesterone group
Description: No progesterone supplementation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low Progesterone group
Description: Progesterone level \<10 ng/mL on ET day. If serum progesterone levels were \<10 ng/ml at ET day, vaginal pills (Lutinus 2\*1) or SC progesterone daily (Prolutex) was given to patients and ET was performed on the same day. Progesterone supplementation was discontinued if there was no pregnancy. Progesterone supplementation at the same dose was continued until 10 gestational weeks for viable pregnancies.
Study: NCT06112015

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bulgarian split squat exercise variations
Description: The participants performed 4 different sessions of Bulgarian split squat exercises-Bulgarian split squat with trunk flexion (BSS flexion), Bulgarian Split squat with trunk neutral (BSS neutral), suspension based Bulgarian split squat with trunk flexion (SBSS flexion), suspension based Bulgarian split squat with trunk neutral (SBSS neutral)-with EMG recordings being taken from the dominant extremity throughout each session. For each exercise, participants were instructed to perform three successful repetitions. Between each repetition, there was a 30-second break, and there was at least 10 minutes in between each of the 4 exercises. The movement was standardized by a metronome. The modified Borg scale was used to ensure that fatigue did not occur before each exercise since it was believed that fatigue could affect exercise performance. When scores reported using the modified Borg scale were 1 or lower, exercise recording was started.
Study: NCT04843306

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biofeedback
Description: Relaxation coaching will be used in this study.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Breathing Control Technique
Description: Active breathing control (ABC) requires patients to reproducibly perform multiple deep-inspiratory breath holds during treatment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Breathing Control Technique
Description: Active breathing control (ABC) requires patients to reproducibly perform multiple deep-inspiratory breath holds during treatment.
Study: NCT05283395

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Netarsudil 0.02%/latanoprost 0.005% fixed dose combination ophthalmic solution
Description: Commercially available ophthalmic solution indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
Study: NCT05657496

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triamcinolone Acetonide 40 mg/ml Inj, Susp
Description: Prepared in clinic by physician or medical staff

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet-rich plasma Inj
Description: Produced from participant's whole blood venous draw of approximately 15 mL. Prepared by centrifuge in clinical office
Study: NCT05579106

Intervention type: DEVICE
Intervention: Nociception Level Monitor (NOL) by Medasense Biometrics Ltd., Israel
Description: The NOL monitor measures various parameters via a sensor in a finger probe that is attached to the patient.~These parameters are:~* Temperature~* Galvanic skin response~* Accelerometer~* Photoplethysmograph (pulse rate, pulse rate variability, photoplethysmograph amplitude)~All this data is combined in an algorithm which produces a number between 0-100. Between 10-25 indicates adequate analgesia, below 10 too much analgesia, above 25 too little analgesia. No actions are taken based on this measurement.

Intervention type: DEVICE
Intervention: Nociception Level Monitor (NOL) by Medasense Biometrics Ltd., Israel
Description: The NOL monitor measures various parameters via a sensor in a finger probe that is attached to the patient.~These parameters are:~* Temperature~* Galvanic skin response~* Accelerometer~* Photoplethysmograph (pulse rate, pulse rate variability, photoplethysmograph amplitude)~All this data is combined in an algorithm which produces a number between 0-100. Between 10-25 indicates adequate analgesia, below 10 too much analgesia, above 25 too little analgesia. No actions are taken based on this measurement.

Intervention type: DEVICE
Intervention: Bispectral index (BIS)
Description: The BIS processes EEG information to provide a direct measurement of the patient's level of consciousness and insight into the effects of anesthesia on the brain.

Intervention type: DEVICE
Intervention: Bispectral index (BIS)
Description: The BIS processes EEG information to provide a direct measurement of the patient's level of consciousness and insight into the effects of anesthesia on the brain.

Intervention type: OTHER
Intervention: Questionnaire perception of the nurse on pain patient
Description: The investigators developed a questionnaire with 7-questions regarding the perception of the responsible nurse on the pain of the patient. When the investigators measured for 8 hours with the BIS and the NOL they will ask the nurse what his or her perception was of the pain of the patient. Eventually the investigators will compare the answers of this questionnaire with the NOL and BIS values that they observed, whether the information corresponds or not.

Intervention type: OTHER
Intervention: Questionnaire perception of the nurse on pain patient
Description: The investigators developed a questionnaire with 7-questions regarding the perception of the responsible nurse on the pain of the patient. When the investigators measured for 8 hours with the BIS and the NOL they will ask the nurse what his or her perception was of the pain of the patient. Eventually the investigators will compare the answers of this questionnaire with the NOL and BIS values that they observed, whether the information corresponds or not.
Study: NCT05221736

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-Guided Ethanol Sclerotherapy (UGES)
Description: Comparison between Ultrasound-Guided Ethanol Sclerotherapy (UGES) \& surgical excision in management of warthin tumor of parotid gland.
Study: NCT05332366

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delgocitinib cream
Description: Cream for topical application

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Delgocitinib cream
Description: Cream for topical application

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Delgocitinib cream vehicle
Description: The cream vehicle is similar to the delgocitinib cream except that it does not contain any active ingredient.
Study: NCT04003805

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standardized Research E-cigarette (SREC)
Description: The device operates at a single output voltage (3.30 ± 0.05 V) and uses sealed disposable 3-mL cartridges with tobacco-flavored e-liquid (\~350 puffs/cartridge). The concentration of nicotine in e-liquid is 15 mg/mL, and the vehicle composition is 50:50 propylene glycol and glycerin. The device uses a battery that can be recharged via a micro USB port. A single charge is designed to sustain more than 400 puffs, which is more than the capacity of an e-liquid cartridge. The e-liquid and the aerosol are well-characterized in terms of chemical impurities and by-products (such as aldehydes), which are minimal. Additional information, including the results of pharmacokinetics study is available via NIDA website: https://www.drugabuse.gov/funding/supplemental-information-nida-e-cig

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Mini-Lozenge
Description: We will use commercially available nicotine mini-lozenges containing 2 or 4 mg nicotine/lozenge (Nicorette, manufactured by GlaxoSmithKline). Dose will be determined per instructions on the package (e.g, if smoking within 30 minutes upon awakening, then 4 mg dose will be prescribed).
Study: NCT05290168

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: abdominal Doppler
Description: 1. Inferior vena cava diameter and distensibility~2. Hepatic vein Doppler~3. Portal vein Doppler~4. Splenic artery and vein Doppler~5. Renal artery and vein Doppler
Study: NCT02154217

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bimatoprost

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Latanoprost/Timolol
Study: NCT04782635

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mobile based application
Description: Application basic function would be support and improve nutrition status of children. Personalization of goals and challenges, daily intake of calories, carbohydrates, proteins, fats, minerals and vitamins will be tracked, food logging, food tracking, meal and supplement reminders, recipes, visual cues (remaining calories) will be notified, episodes of vomiting, meals missed, diarrhea, nausea will be recorded , meal planned according to the food preferences of child, food composition table, nutrition blogs and articles

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Pamphlet
Description: A pamphlet which will be provide knowledge to the patients
Study: NCT04577573

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sensory brace
Description: A a size- and position-adjustable arm brace with weight-support capability and housing for vibration motors and EMG sensors. Position adjustment allows for physical therapists to find and recommend arm postures that are clinically relevant to~each person. The participant can then isometrically push/resist against the brace to strengthen target muscles while performing VR reach-to-touch. The person will receive visual feedback from the virtual environment to train movement performance and vibrotactile feedback at tendons to subconsciously adjust their muscle activation patterns

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sensory brace
Description: A a size- and position-adjustable arm brace with weight-support capability and housing for vibration motors and EMG sensors. Position adjustment allows for physical therapists to find and recommend arm postures that are clinically relevant to~each person. The participant can then isometrically push/resist against the brace to strengthen target muscles while performing VR reach-to-touch. The person will receive visual feedback from the virtual environment to train movement performance and vibrotactile feedback at tendons to subconsciously adjust their muscle activation patterns
Study: NCT06405880

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacist-led care pathway
Description: Participants in the intervention arm will receive the care using a shared decision-making pharmacist-led care pathway designed to guide the cardiovascular (CV) risk reduction process. The pharmacist-led care pathway is modelled after the largest CV risk reduction randomized controlled trial in a community pharmacy setting (RxEACH Study), and based upon the latest CV risk reduction guidelines, such as C-CHANGE. This pathway will be built into a computer web-based program and include step-by-step, algorithm-guided patient assessment to calculate the participant's estimated CV risk. The participant and pharmacist will be guided by the care pathway to review the participant's estimated CV risk and contributing CV risk factors and engage in shared decision-making to manage the participant's CV risk factors using lifestyle changes and/or pharmacological treatment as clinically appropriate.
Study: NCT05787964

Intervention type: PROCEDURE
Intervention: Biological sample collection
Description: Whole blood (blood draw/phlebotomy) will be obtained to proceed with immunologic analysis of samples. Collection of biologic samples will occur up to 12 months.

Intervention type: PROCEDURE
Intervention: Biological sample collection
Description: Whole blood (blood draw/phlebotomy) will be obtained to proceed with immunologic analysis of samples. Collection of biologic samples will occur up to 12 months.

Intervention type: PROCEDURE
Intervention: Biological sample collection
Description: Whole blood (blood draw/phlebotomy) will be obtained to proceed with immunologic analysis of samples. Collection of biologic samples will occur up to 12 months.
Study: NCT05261815

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound Therapy
Description: Ultrasound Therapy improves the pain management in patients with herniation. It eases down the severity of symptoms as well.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Laser Therapy
Description: Treatment of low disc herniation should be non-surgical, pharmacological and by physical therapy modalities. Laser radiation with high intensity used as a modality called high intensity laser therapy. It is used to relieve the pain by three process; Photo-chemical, Photo-thermal, Photo-mechanical. High Intensity Laser Therapy uses high intensity laser irradiation and low light absorption.
Study: NCT06113146

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ultra-processed slow eating rate diet
Description: Consuming ultra-processed slow eating rate meals (served ad libitum) and snacks. Eating rate is manipulated through food texture, for example foods with a hard texture that require a long chewing duration before a bite of food can be swallowed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ultra-processed slow eating rate diet
Description: Consuming ultra-processed slow eating rate meals (served ad libitum) and snacks. Eating rate is manipulated through food texture, for example foods with a hard texture that require a long chewing duration before a bite of food can be swallowed.
Study: NCT04711720

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VTS surgical navigation system
Description: TheVTS surgical navigation system can accurately match the preoperative and intraoperative image data with the patient's anatomical structure on the operating table, track the surgical instruments during the operation, and update the position of the surgical instruments on the patient's image in real time, so that the doctor can clearly understand the position of the surgical instruments relative to the patient's anatomical structure, and make the operation procedure more accurate and safer.
Study: NCT04920526

Intervention type: DRUG
Intervention: Quadrivalent HPV [Type 6, 11, 16 and 18] L1 Virus-Like Particle Vaccine
Description: No intervention will be administered
Study: NCT04277247

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botulinum toxin type A
Description: A standardized dose will be injected in each muscle: 25 Units of BTXA in the extensor hallucis longus in 1 site, 50 Units of BTXA in the flexor digitorum brevis in 2 sites and 25 Units of BTXA in the tibialis posterior in 1 site.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% saline placebo injection
Study: NCT05640089

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI-based neurofeedback
Description: Participants use fMRI-based neurofeedback to train the upregulation of brain areas that respond to positive affective pictures (as identified during a functional localiser scan).
Study: NCT05370092

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Percutaneous needle electrolysis
Description: Electrolysis is the process by which water (H2O) and sodium chloride (NaCl) molecules, which are present in the biological tissues and body compartments of our organism, are organically broken down into their constituent chemical elements, regrouping to create entirely new substances such as sodium hydroxide (NaOH), hydrogen gas (H2) and chlorine gas (Cl2). This process occurs thanks to the passage of a flow of direct electric current, also known as galvanic current, which is a totally athermal process. The passage of this current allows a local inflammatory response to occur (increase in lymphocytes and macrophages) as well as an increase in vasodilatation, inducing phagocytosis and biological stimulation of tendon repair.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic exercise
Description: The first exercise they will perform will be the Short-Foot Exercise holding the position 5 seconds isometrically. The second exercise will be plantar flexion of the ankle with adduction of the foot and inversion with elastic band in its concentric and eccentric phase

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic exercise
Description: The first exercise they will perform will be the Short-Foot Exercise holding the position 5 seconds isometrically. The second exercise will be plantar flexion of the ankle with adduction of the foot and inversion with elastic band in its concentric and eccentric phase

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual therapy
Description: The manual therapy (TM) treatment for tendinopathies is mainly focused on soft tissue mobilization and deep transverse friction massage (Cyriax).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: The manual therapy (TM) treatment for tendinopathies is mainly focused on soft tissue mobilization and deep transverse friction massage (Cyriax).
Study: NCT06113146

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed fast eating rate diet
Description: Consuming ultra-processed fast eating rate meals (served ad libitum) and snacks. Eating rate is manipulated through food texture, for example foods with a soft texture that require little chewing before a bite of food can be swallowed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed fast eating rate diet
Description: Consuming ultra-processed fast eating rate meals (served ad libitum) and snacks. Eating rate is manipulated through food texture, for example foods with a soft texture that require little chewing before a bite of food can be swallowed.
Study: NCT05857267

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dorzolamide / Timolol Ophthalmic Solution
Description: Dorzolamide-timolol fixed combination in a preservative-free multidose device

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dorzolamide/timolol
Description: Dorzolamide-timolol BAK-preserved fixed combination
Study: NCT06271590

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sirolimus Drug Coated Balloon
Description: Magic TouchTM (Concept Medical) is a semi-compliant sirolimus drug coated balloon (SCB) for PCI, based on a polymer-free and nanocarrier based drug delivery technology.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Drug eluting stents (DES)
Description: For subjects randomized to the control group (DES), the treating physician will choose an FDA cleared DES (ZES or EES) and follow lesion preparation and stent deployment according to the Instructions per use (IFU) and institutional practices.
Study: NCT06186245

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early feeding with an oral diet
Description: Participants in the treatment arm will be initiated on a clear liquid diet on day 1 of medical ICU admission. Diet will be progressed on day 2 to full liquid diet or diabetic diet as patient tolerates based on which diet the patient would prefer.
Study: NCT04795128

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: IBI322
Description: Recombinant anti-human CD47/PD-L1 bispecific antibody injection
Study: NCT06488625

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low-Dose CICR-NAM
Description: 2 g/d CICR-NAM (blinded)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High-Dose CICR-NAM
Description: 3 g/d CICR-NAM (blinded)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0 g/d CICR-NAM (blinded)
Description: Placebo (blinded)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Open-Label
Description: 3 g/d CICR-NAM (open label)
Study: NCT05232669

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Cocoa extract
Description: 2 capsules each day containing a total of 500 mg cocoa flavanols, including 80 mg (-)-epicatechin, and 50 mg theobromine

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Cocoa extract
Description: 2 capsules each day containing a total of 500 mg cocoa flavanols, including 80 mg (-)-epicatechin, and 50 mg theobromine

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Cocoa extract placebo
Description: Cocoa extract placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Cocoa extract placebo
Description: Cocoa extract placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Multivitamin
Description: Multivitamin

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Multivitamin
Description: Multivitamin

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Multivitamin placebo
Description: Multivitamin placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Multivitamin placebo
Description: Multivitamin placebo