TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05420129

Intervention type: DEVICE
Intervention: MAD Therapy
Description: Participants will be treated with a Mandibular Advancement Device therapy

Intervention type: DEVICE
Intervention: CPAP Therapy
Description: Participants will be treated with a Continuous Positive Airway Pressure therapy
Study: NCT05148013

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercise
Description: All participants will be given a basic introduction to the Pilates-based exercises and will be taught how to activate the core muscles, which entails isometric contraction of the transverses abdominis, pelvic floor, and multifidus muscles while exhaling during diaphragmatic breathing, before beginning the exercise program. The Pilates exercise program will consist of floor exercises on a mat, including the following exercises: one-leg kick, single leg stretch, shoulder bridge, the hundred, one leg circle, and swimming. All exercises progressed at three degrees of difficulty: basic, intermediate, and advanced. Depending on the patient's tolerance, each exercise will be done for 8-10 repetitions. The treatment plan included a five-minute warm-up, twenty minutes of exercise, and a five-minute cool-down.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF exercise
Description: The PNF techniques utilized in the PNF exercise group will include a combination of isotonics, rhythmic stabilization, and repeated stretch. The exercises which will be performed are; (1) Trunk rotation in sitting position (1a) Chopping to the left and right and (1b) Lifting to the left and right, (2) Rolling activity (2a) Resistance to pelvic anterior patterns 2(b) Resistance to posterior patterns, 2(c) Combination of scapula and pelvis, 2(d) Combination of scapula and pelvis (i.e. asymmetrical exercise for trunk extension: the scapula moves in posterior elevation, the pelvis in posterior depression) and (3) Bridging activity (3a) Stabilize the pelvis in its neutral position, 3(b) Bridging lower trunk rotation and, 3(c) Bridging on two legs in the supine position.
Study: NCT06514391

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: compressive single piece dental implant
Description: 4 inter-foraminal single piece compressive dental implants were placed in the mandible via flapless protocol by the aid of stereolithographic surgical guide
Study: NCT05413265

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Phases 1 and 2
Description: Phase 1 participants will help inform the cultural adaptation of the study design and materials. Phase 2 will enroll 10 dyads (20 individuals) of AN/AI people who smoke and a family member. Dyad participants will help beta-test the feasibility and acceptability of the financial incentives intervention.
Study: NCT05743842

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TriSalus™ TriNav™Infusion System
Description: Given by Infusion

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Angiogram
Description: X-ray photograph

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Y90-radioembolization procedure
Description: procedure
Study: NCT06459089

Intervention type: BEHAVIORAL
Intervention: Selection of the parent according to children preference
Description: The children will select the parent who will accompany them during the anesthesia induction

Intervention type: BEHAVIORAL
Intervention: Selection of the parent according to children preference
Description: The children will select the parent who will accompany them during the anesthesia induction

Intervention type: BEHAVIORAL
Intervention: Bringing the favorite toy of the children that will accompany the child during their perioperative period
Description: The children will bring tiheir favorite toy that will accompany them during their perioperative period
Study: NCT05966363

Intervention type: RADIATION
Intervention: Nanodot
Description: Radiation measurements using nanodots placed on the eyes, ears, neck and lower abdomen during an imaging examination.

Intervention type: RADIATION
Intervention: Nanodot
Description: Radiation measurements using nanodots placed on the eyes, ears, neck and lower abdomen during an imaging examination.
Study: NCT05992610

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chemotherapy (carboplatin+paclitaxel) with concomitant low dose ionizing radiotherapy
Description: Chemotherapy based on carboplatin 6 AUC + paclitaxel 75 mg/m2.~Radiotherapy:~D:1 - 2 x 0,5 Gy (first dose up to one hour after the end of the carboplatin infusion, second dose 3 to 6 hours later), D:2 - 2 x 0,5 Gy (interval between doses not less than 3 hours), D:8 and D:15 - 2 x 0,5 Gy (first dose up to one hour after the end of the chemotherapeutic infusion, second dose 3 to 6 hours later).
Study: NCT06482697

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: total colpocleisis
Description: Total colpocleisis refers to the process where, during the dissection of the anterior and posterior vaginal walls to remove the vaginal mucosa, no holes are left. When suturing, the anterior and posterior vaginal walls are completely interrupted with mattress sutures, and no holes are left on either side or at the top of the vagina.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: partial colpocleisis (LeFort)
Description: LeFort involves the removal of a rectangular piece of mucosa from the anterior and posterior walls of the vagina, leaving a strip of mucosa 2 to 3 cm wide on each side of the vagina. The dissection is carried out close to the vaginal mucosa while preserving the vaginal bladder fascia as much as possible, creating channels on both sides of the vagina.
Study: NCT04817137

Intervention type: DEVICE
Group type: OTHER
Intervention: CareTaker PDA Device
Description: Non-invasive blood pressure monitoring
Study: NCT05411588

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07275315
Description: Active drug

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05671484

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transversalis Fascial Plane Block
Description: Patients will receive ultrasound-guided transversalis fascial plane block with 0,3 ml/kg of bupivacaine 0.25% just after general anesthesia induction
Study: NCT04043234

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RESCU
Description: Retrospectively Supervised Classification Updating (RESCU) is founded on two innovations that promise significant improvement in performance and outcome. The first is a highly robust machine intelligence algorithm, an Extreme Learning Machine with Adaptive Sparse Representation (EASRC), and the second is a novel adaptive learning algorithm and communication interface we call Nessa. We contend that these two technologies allow the prosthetic device to adapt to its user from the initial fitting through continuing, long-term use in the activities of daily living, shifting the paradigm of training from the current prospective data gathering methods to a more dynamic retrospective application.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pattern Recognition
Description: Pattern recognition prostheses associate the patterns of activity of multiple EMG sites to the action of a prosthesis. Such strategies have historically required prospective calibration of the EMG activation patterns.
Study: NCT05997992

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: Electroacupuncture is a form of acupuncture where a small electric current is passed between pairs of acupuncture needles. According to some acupuncturists, this practice augments the use of regular acupuncture, can restore health and well-being, and is particularly good for treating pain.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: sham acupuncture
Description: Acupuncture does not penetrate the skin, and the electroacupuncture machine is not plugged in.
Study: NCT05845333

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.
Study: NCT05485597

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Myosuit-based gait training
Description: In a period of four weeks participants will undergo eight individual task-specific overground gait training sessions with the Myosuit. The sessions will be started with a therapist, and if possible and as soon as possible, the patient will train with an assistant. During the therapy sessions, the patient will be asked to perform various task-specific exercises with the Myosuit, such as Sit-to-stand-, Balance- and walking exercises. Depending on the individual skill level of the participant, a higher level of difficulty in task-specific exercises can be performed. The training sessions are set to last 45 minutes. All training sessions will be accompanied by a certified (physio)therapist or trained assistant and a study investigator.
Study: NCT05433714

Intervention type: OTHER
Intervention: Assesment
Description: The figure of walk test, Berg Balance scale, Timed 25-Foot Walk, Timed up and go test, Foursquare walk test
Study: NCT05845333

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.

Intervention type: OTHER
Intervention: Decision task
Description: Participants will complete a simple and/or moral decision making functional MRI task.
Study: NCT05925413

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab+TACE
Description: Cadonilimab: 15mg/kg Q3W Day1 Select the best TACE treatment strategy. Traditional TACE (cTACE) or DEB-TACE can be selected. TACE treatment can be continued as needed based on disease control. The combination of cadonilimab is given 3 to 7 days after the first TACE treatment, and the subsequent administration of cardonilizumab is given once every 3 weeks, if the time overlaps with TACE treatment, it is generally administered 3 to 7 days after TACE treatment. Treatment was discontinued until intolerable toxicity, death, withdrawal of informed consent, initiation of a new antitumor therapy, or other reason specified in the protocol, whichever occurs first. Patients in this study received cadonilimab for up to 24 months.
Study: NCT05696353

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: In-vehicle Device
Description: The Azūga™ in-vehicle driving feedback technology, which consists of a pager-sized device plugged into the vehicle's on-board diagnostic port (installed in the teen's car) and a smart phone app (downloaded on the teen's smart phone), will be installed/downloaded. Three types of feedback will be provided to intervention teens: 1) Direct audio feedback from the installed device; 2) Detailed cumulative driving data via the smart phone app and study website; and 3) A customized biweekly driving summary report via study website.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: In-vehicle Device
Description: The Azūga™ in-vehicle driving feedback technology, which consists of a pager-sized device plugged into the vehicle's on-board diagnostic port (installed in the teen's car) and a smart phone app (downloaded on the teen's smart phone), will be installed/downloaded. Three types of feedback will be provided to intervention teens: 1) Direct audio feedback from the installed device; 2) Detailed cumulative driving data via the smart phone app and study website; and 3) A customized biweekly driving summary report via study website.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Expert-Delivered Parent Communication Training
Description: An individualized virtual training in communication strategies about teen driving safety along with a booster session will be delivered by a traffic safety communication specialist to parents in the Feedback and Expert-Delivered Parent Communication Intervention Group. Intervention parents in this group will also be provided with access to an online parent-teen safe driving communication guide.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer-Delivered Parent Communication Training
Description: An individualized virtual training in communication strategies about teen driving safety along with a booster session will be delivered by a peer trainer who is a parent of teen with traffic citation and has participated in the Feedback and Peer-Delivered Parent Communication Intervention Group. Intervention parents in this group will also be provided with access to an online parent-teen safe driving communication guide.
Study: NCT04577716

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography
Description: PET scan using the 18F-Sodium Fluoride radiotracer followed by an attenuation correction CT scan

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography
Description: PET scan using the 18F-Sodium Fluoride radiotracer followed by an attenuation correction CT scan

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography
Description: PET scan using the 18F-Sodium Fluoride radiotracer followed by an attenuation correction CT scan

Intervention type: DIAGNOSTIC_TEST
Intervention: CT Aortic Angiogram
Description: CT scan to assess aortic morphology and contextualise PET scan

Intervention type: DIAGNOSTIC_TEST
Intervention: CT Aortic Angiogram
Description: CT scan to assess aortic morphology and contextualise PET scan
Study: NCT05256160

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TMS Paired-Pulse assessment of cortical excitability
Description: Using the paired-pulse TMS paradigm, intracortical inhibition and facilitation of cortical circuitry will be assessed by stimulating the motor cortex and using the electromyographic (EMG) response of a target muscle as readout. In such studies, a conditioning stimulus modulates the amplitude of the motor-evoked potential (MEP) produced by the test stimulus. Depending on the inter-stimulus interval, effects can be attributed to different aspects of cortical processing. Brief intervals (1-5 ms) will be used to assess short-interval intracortical inhibition (SICI) and short-interval intracortical facilitation (SICF), intermediate intervals (7-20 ms) to assess intracortical facilitation (ICF) and long intervals (50-200 ms) to assess long-interval intracortical inhibition (LICI).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TMS Paired-Pulse assessment of cortical excitability
Description: Using the paired-pulse TMS paradigm, intracortical inhibition and facilitation of cortical circuitry will be assessed by stimulating the motor cortex and using the electromyographic (EMG) response of a target muscle as readout. In such studies, a conditioning stimulus modulates the amplitude of the motor-evoked potential (MEP) produced by the test stimulus. Depending on the inter-stimulus interval, effects can be attributed to different aspects of cortical processing. Brief intervals (1-5 ms) will be used to assess short-interval intracortical inhibition (SICI) and short-interval intracortical facilitation (SICF), intermediate intervals (7-20 ms) to assess intracortical facilitation (ICF) and long intervals (50-200 ms) to assess long-interval intracortical inhibition (LICI).
Study: NCT04577716

Intervention type: DIAGNOSTIC_TEST
Intervention: 12-month CT Aortic Angiogram
Description: CT scan to assess aortic morphology and the stent graft

Intervention type: OTHER
Intervention: 24-month review
Description: This will consist of a telephone consultation with the study participant and review of electronic clinical records
Study: NCT05963412

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Meaning Centered Coping Program
Description: Meaning Centered Coping Program is a psychological intervention program developed for women diagnosed with breast cancer, based on the Meaning Making Model (Park, 2010; Park and Folkman, 1997) and Wong's (2010) principles of Meaning Therapy. Each weekly session had specific topics. These are:~Session 1: Guiding patients to tell the story of their breast cancer and psycho-education; Session 2: Encouraging patients to talk about the effects of breast cancer on their lives and learning to accept their difficult emotions; Session 3: Focusing on cognition through the meaning attributed to breast cancer; Session 4: Learning to take alternative perspectives and defusing their negative thoughts; Session 5: Exploring personal strengths; Session 6: İdentifying important life values and moving toward value-based actions; Session 7: Finding meaning in breast cancer and life; Session 8: Focusing on Future plans and hopes
Study: NCT05731908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 690517
Description: BI 690517
Study: NCT05256160

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Autonomic activity
Description: Autonomic function will be determined using continuously recorded EKG and used as covariates to investigate any systematic impact on cortical excitability measures collected with the paired-pulse protocols.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Autonomic activity
Description: Autonomic function will be determined using continuously recorded EKG and used as covariates to investigate any systematic impact on cortical excitability measures collected with the paired-pulse protocols.
Study: NCT05731908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 690517
Description: BI 690517

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 690517
Description: BI 690517
Study: NCT05659797

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BPET/DBT imaging
Description: Imaging of the breast with a novel device combining dedicated Breast Positron Emission Tomography (BPET) and Digital Breast Tomosynthesis (DBT) following intravenous injection of \[18F\]-Fluoroestradiol (FES).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-FES
Description: Radiolabelled fluoroestradiol for PET imaging
Study: NCT06355609

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sunvozertinib in combination with Anlotinib
Description: Sunvozertinib 300 mg once daily (QD) with Anlotinib 8mg once daily （QD in Day 1-14），21 days in one cycle.
Study: NCT05958394

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SkillFlix for Parents
Description: A Microskills video training library on communication skills for talking to youth about relationships and sexual health topics.
Study: NCT05232968

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Long-term exercise program
Description: Training intervention (aerobic-strength training) will combine a 1-hour aerobics training, which requires movement coordination, and two 1-hour lessons, combining strength load (25 minutes, 50-60% 1RM, which gradually increases in proportion to increasing strength, 8-12 repetitions, training all major muscle groups) and aerobic exercise (25 minutes of Nordic walking or stationary bike), with a short warm-up at the beginning and stretching at the end. The individualized training program will be based on the determination of physical fitness (Rockport gait test) and muscle strength (dynamometry).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Short-term exercise program
Description: Training intervention (aerobic-strength training) will combine a 1-hour aerobics training, which requires movement coordination, and two 1-hour lessons, combining strength load (25 minutes, 50-60% 1RM, which gradually increases in proportion to increasing strength, 8-12 repetitions, training all major muscle groups) and aerobic exercise (25 minutes of Nordic walking or stationary bike), with a short warm-up at the beginning and stretching at the end. The individualized training program will be based on the determination of physical fitness (Rockport gait test) and muscle strength (dynamometry).
Study: NCT05573750

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Singing group
Description: Intervention involves singing groups with person with dementia and carer. Please see earlier descriptions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Singing group
Description: Intervention involves singing groups with person with dementia and carer. Please see earlier descriptions.
Study: NCT05540249

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: carbohydrates
Description: Patients will orally consume 355mL CHO after 20:00 the evening before surgery.
Study: NCT06018493

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: focused power ultrasound mediate inferior perirenal adipose tissue modification
Description: This novel focused power ultrasound is an externally delivered, completely noninvasive focused therapeutic ultrasound device. It is capable of focusing the resulting ultrasound beam to a small cigar-shaped volume and monitoring the temperature of the target area, which leads to the rapid elevation of the peri-renal adipose tissue temperature and the destruction of target tissue eventually.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham-control group
Description: participants will receive the sham control therapy(including peri-renal fat ultrasonic measurement and localization,focused ultrasound treatment parameters setting),however,without initiating the focused ultrasound equipment.
Study: NCT06126718

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR201
Description: One-dosage on D1 and review pharmacokinetic and safety until D112 after drug given

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cosentyx（Secukinumab ）
Description: One-dosage on D1 and review pharmacokinetic and safety until D112 after drug given
Study: NCT05451290

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab, apatinib, gemcitabine, oxaliplatin, tegafur
Description: Perioperative treatment: camrelizumab plus apatinib in combination with GEMOX 2-4 cycles (neoadjuvant); camrelizumab plus tegafur up to 1 year (adjuvant).
Study: NCT05176197

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Almond
Description: Participants will consume almonds every day for 16 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Participants will consume pretzels every day for 16 weeks.
Study: NCT05347225

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nemtabrutinib
Description: Nemtabrutinib tablets will be administered orally QD.
Study: NCT05229211

Intervention type: DEVICE
Intervention: Cardiac monitoring
Description: Continuous ECG monitoring via VitalConnect patch worn on the chest.
Study: NCT05849714

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peri-intervention Diabetes Management Algorithm (DIAPI)
Description: Patients and healthcare workers will apply DIAPI's orders.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Patients and healthcare workers will apply the mainstay management, which is using the treating-physician's recommendations instead of DIAPI's.