TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05579522

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fat graft injection
Description: Fat graft injection in the interdental papilla.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic acid injection
Description: Hyaluronic acid injection in the interdental papilla
Study: NCT06276985

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low intensity pulsed ultrasound and iPRF
Description: iPRF and LIPUS has been found to speed up OTM by stimulating the RANK/RANKL/OPG system to initiate osteoclast formation.
Study: NCT05090462

Intervention type: DEVICE
Intervention: PICO dressing
Description: Negative Pressure Wound Therapy device
Study: NCT04895540

Intervention type: DIAGNOSTIC_TEST
Intervention: ECG
Description: All study subjects will undergo ECG recording.

Intervention type: DIAGNOSTIC_TEST
Intervention: ECG
Description: All study subjects will undergo ECG recording.
Study: NCT06692946

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Treatement as Usual
Description: Cognitive Behavioral Therapy (CBT) is a structured, short-term psychological treatment that focuses on identifying and changing negative thought patterns and behaviors. It aims to help individuals develop healthier ways of thinking and coping with challenges by addressing both cognitive (thought) and behavioral components.~Parent training is an educational intervention where parents learn strategies and techniques to effectively manage their child's behavior and support their development, often used to address challenges associated with conditions like autism or ADHD.
Study: NCT06693323

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AHCC®capsules
Description: Given PO
Study: NCT04895540

Intervention type: DIAGNOSTIC_TEST
Intervention: ECG
Description: All study subjects will undergo ECG recording.

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography
Description: All study subjects will undergo transthoracic echocardiography

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography
Description: All study subjects will undergo transthoracic echocardiography

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography
Description: All study subjects will undergo transthoracic echocardiography

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac MRI
Description: All ACM patients and SCD survivors will undergo cardiac MRI testing.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ambulatory ECG recording
Description: All ACM patients and SCD survivors will undergo 24-hour ambulatory ECG recording
Study: NCT06692218

Intervention type: DEVICE
Group type: OTHER
Intervention: Leadless pacemaker
Description: Patients who will implant leadless pacemakers or already implanted leadless pacemakers since 1 Jan 2015 will be recruited. After the implantation, patients will be invited back for a noncontrast, ECG-gated CT heart. It will be timed at the end diastole and a 3D reconstruction will be performed.
Study: NCT05079841

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electric breast pump
Description: Participants randomized to the intrapartum nipple stimulation will use electric breast pump or nipple stimulate by hand (if preferred) (intervention) to induce labor for at least 2 hours

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exogenous oxytocin intravenous infusion without nipple stimulation.
Description: Participants randomized to the standard care arm will use exogenous oxytocin intravenous infusion to induce labor as current standard of care
Study: NCT06317402

Intervention type: OTHER
Intervention: malnutrition questionary
Description: At the patient's bed, using a questionnaire, evaluators take anthropometric measurements (weight, height, muscle strength) and collect biological data (albumin, pre-albumin, CRP, if available in the medical record) to establish nutritional status according to HAS criteria for undernutrition 2019-2021 and 2003-2007.
Study: NCT06399445

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: conventional cold tonsillectomy and curettage adenoidectomy
Description: After entering the operating room, the children will be monitored (electrodes for ECG, blood pressure cuff and pulse oximeter). We will use gas mixture of O2/N20 50/50% and concentration of Sevoflurane set between 5% and 6 % with a dose of 6 L/min (1.0 -1.3 MAC) for 10 breaths, then we will set 4 % concentration of Sevoflurane. After loss of consciousness, intravenous line 22 G will be obtained and 0.9 % saline infuse with a dose of 4 ml/kg/hr, Fentanyl 1 mcg/kg iv. and Propofol 2 mg/kg. During stage III of anesthetic depth, we will perform orotracheal intubation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional cold tonsillectomy and curettage adenoidectomy
Description: After entering the operating room, the children will be monitored (electrodes for ECG, blood pressure cuff and pulse oximeter). We will use gas mixture of O2/N20 50/50% and concentration of Sevoflurane set between 5% and 6 % with a dose of 6 L/min (1.0 -1.3 MAC) for 10 breaths, then we will set 4 % concentration of Sevoflurane. After loss of consciousness, intravenous line 22 G will be obtained and 0.9 % saline infuse with a dose of 4 ml/kg/hr, Fentanyl 1 mcg/kg iv. and Propofol 2 mg/kg. During stage III of anesthetic depth, we will perform orotracheal intubation.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rocuronium Bromide
Description: After entering the operating room, chlidren will be monitored (electrodes for ECG, blood pressure cuff and pulse oximeter). We will use gas mixture of O2/N20 50/50% and concentration of Sevoflurane set between 5% and 6 % with a dose of 6 L/min (1.0 -1.3 MAC) for 10 breaths. After loss of consciousness, we will turn off Sevoflurane, intravenous line 22 G will be obtained and 0.9 % saline infuse with a dose of 4 ml/kg/hr, 1 mcg/kg Fentanyl, 2.5 mg/kg Propofol and 0.6 mg/kg Rocuronium bromide (esmeron). After 2 min, orotracheal intubation will be performed.
Study: NCT05134571

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Laronidase
Description: Solution for injection; Intravenous
Study: NCT04661202

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: multimodal exercise training
Description: A supervised moderate-intensity exercise training session, which will include aerobic exercise with a stationary exercise bike, resistance exercise using dumbbell, theraband band, or gym ball for each major muscle groups and core muscles (including pelvic floor muscle (PFM) training with biofeedback), and stretching exercise, twice a week for 8 weeks. All exercises will be individualized based on participant's heart rate reserve and Rate of Perceived Exertion (RPE). An oximeter and a sphygmomanometer will be used to monitor the heart rate, oxygen saturation and blood pressure of the participants to ensure safety.~A home exercise program will include a walking exercise for 30 minutes per day and a PFM training with the aim of completing 1\~3 sets of 8\~12 submaximal contraction of PFM by holding 6\~10 seconds with 12\~20 seconds of rest between each contraction, and it will end with 3 maximal PFM contractions by holding 1\~3 seconds 3\~6 seconds of rest between each contraction.
Study: NCT06559956

Intervention type: OTHER
Intervention: Daytime titration polysomnography
Description: A titration polysomnography assesses the device settings and, if necessary, the stimulation strength will be adjusted based on observed respiratory events and/or snoring. Patients in the daytime titration PSG cohort were instructed to refrain from sleeping during the night, and in the morning, they were permitted to sleep in a soundproof room without daylight at the sleep lab.
Study: NCT04995354

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EGF loaded Hydrogel
Description: Patients will receive 25 Ug/day of EGF. This is the estimated daily dose that will be obtained when the patient applies the gel thrice daily. Patients will receive the treatment for one week

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hydrogel
Description: Non-medicated self-healing hydrogel to be applied three times a day for 1 week
Study: NCT06209034

Intervention type: OTHER
Group type: OTHER
Intervention: Optic nerve sheath measurement
Description: ONSD was measured bilaterally 3 mm posterior to the papilla. Transverse measurements were made for each optic nerve.
Study: NCT04895540

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac EP study
Description: ACM patients and SCD survivors will undergo diagnostic cardiac Electrophysiology testing.
Study: NCT06563713

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0902 injection
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0902 injection
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0902 injection
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0902 injection
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0902 injection
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive the administration dose on Day 0 following protocol requirements

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive the administration dose on Day 0 following protocol requirements
Study: NCT06318546

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine Injection [Precedex],,,
Description: patients will receive 0.5ml (10 µg) Dexmedetomidine as an adjuvant to 2.2ml hyperbaric Bupivacaine hydrochloride 0.5%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: will be given 0.5 ml of one ampoule (2ml) of 100µg fentanyl (Fentanyl Hameln® 0.1mg/2ml - Sunny pharm) equivalent to 25 µg fentanyl as an adjuvant to 2.2ml hyperbaric Bupivacaine hydrochloride 0.5%
Study: NCT04895540

Intervention type: GENETIC
Intervention: All study subjects will undergo sample collection for genetic testing.
Description: Blood samples and buccal swab will be collected from study subjects for genetic testing.

Intervention type: GENETIC
Intervention: All study subjects will undergo sample collection for genetic testing.
Description: Blood samples and buccal swab will be collected from study subjects for genetic testing.

Intervention type: GENETIC
Intervention: All study subjects will undergo sample collection for genetic testing.
Description: Blood samples and buccal swab will be collected from study subjects for genetic testing.
Study: NCT06154850

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Immersive virtual reality
Description: Oculus Quest 2 will be used with NatureTrek application for 10 minutes.
Study: NCT05174754

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physician-prescribed Exercise Programme
Description: A 20-week structured exercise programme derived and supervised by a Sports Medicine Physician following the FITT Principles

Intervention type: DRUG
Group type: OTHER
Intervention: Best Medical Therapy
Description: Best medical therapy with biologic agent or small-molecule therapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Best Medical Therapy
Description: Best medical therapy with biologic agent or small-molecule therapy
Study: NCT05024487

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Clinical Examination
Description: Given the most frequent causes of AD, the above-mentioned trigger stimuli will be used. All these procedures are commonly used in SCI people.
Study: NCT06045390

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App
Description: App features (App will be used during the office visit):~* Pictorial representation of drops (color-coded) and schedule.~* Quiz to assess understanding of the regimen.~* Narrated instructions (language-concordant) on how and when (frequency and eye laterality) to take each drop.~* Graphical print-out of the regimen.
Study: NCT05654363

Intervention type: PROCEDURE
Intervention: Administration of morphine by intrathecal route
Description: Lumbar puncture was performed before the induction of general anesthesia, in the operating room. Spinal anesthesia was performed in sitting position using a midline approach into the L3-L4 or L4-L5 interspaces with a 25ga pencil-point spinal needle administering 75-100 mcg morphine, with or without local anesthetic (levobupivacaine 0,5% 10-15 mg or bupivacaine 0,5% 10-15 mg or ropivacaine 0,5% 10-15 mg), depending on the anesthesiologist's preference. General anesthesia was then conducted according to clinical practice. All patients were transferred in the Post-Anesthesia Care Unit (PACU) at the end of surgery. Throughout the first 48 postoperative hours, all patients were regularly evaluated in the hospital ward by a member of the Acute Pain Service Team.

Intervention type: PROCEDURE
Intervention: Administration of morphine by intravenous route
Description: General anesthesia was conducted according to clinical practice and a morphine bolus was administered before emergence from anesthesia according to clinical needs. All patients were then transferred in the Post-Anesthesia Care Unit (PACU) at the end of surgery and received Patient-Controlled Analgesia (PCA) with morphine 1mg/mL (CADD®-Solis 2110 Infusion System, Smiths Medical ASD, Inc., USA, 1 mL bolus on demand, no background infusion, 7 minute lockout, max 8 mg/h). Throughout the first 48 postoperative hours, all patients were regularly evaluated in the hospital ward by a member of the Acute Pain Service Team.
Study: NCT04943887

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: eSupport Health Weekly Group Sessions for PwMS
Description: A formal semi-structured program of psychoeducational support delivered in an online weekly small group format by health coaches (licensed therapists) who specialize in MS.
Study: NCT06154850

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Non-immersive virtual reality
Description: Patients will watch a video including scenes from NatureTrek application on a screen.
Study: NCT04945369

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: clinical and biological measurements and questionnaires
Description: Blood and urinary samples collection for evaluation of insulin resistance and of renal function analysis.~Assessment of body composition by BOP-POD and by impedancemetry. Assessment of pulse wave by popmetre. Assessment of physical activity by accelerometer and by questionnaire Questionnaires for analysis of eating behaviour
Study: NCT05768672

Intervention type: BEHAVIORAL
Intervention: Experimental Task
Description: The main task is an olfactory version of a traditional Go/No-Go task (Albayay et al., 2019): it includes the delivery of either an odour or clean air prior to the presentation of a visual target Moreover, all participants will be assessed with the italian version of the Stroop color and word test (Caffarra et al., 2004) to evaluate inhibition, together with selective and sustained attention. This neuropsychological test consists of three tables, showing color words (W), colored circles (C), and color words printed in incongruent ink (i.e., red printed in blue ink, CW), respectively. The Stroop effect consists of a delayed response when words have to be named according to the color of the ink, ignoring the meaning of the printed word.

Intervention type: BEHAVIORAL
Intervention: Experimental Task
Description: The main task is an olfactory version of a traditional Go/No-Go task (Albayay et al., 2019): it includes the delivery of either an odour or clean air prior to the presentation of a visual target Moreover, all participants will be assessed with the italian version of the Stroop color and word test (Caffarra et al., 2004) to evaluate inhibition, together with selective and sustained attention. This neuropsychological test consists of three tables, showing color words (W), colored circles (C), and color words printed in incongruent ink (i.e., red printed in blue ink, CW), respectively. The Stroop effect consists of a delayed response when words have to be named according to the color of the ink, ignoring the meaning of the printed word.
Study: NCT06419907

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Type 2 Live Well (structured diabetes self management education programme)
Description: Structured diabetes self management education programme designed to support those with type 2 diabetes self care and prevent long term associated complications.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Type 2 Live Well (structured diabetes self management education programme)
Description: Structured diabetes self management education programme designed to support those with type 2 diabetes self care and prevent long term associated complications.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Type 2 Live Well (structured diabetes self management education programme)
Description: Structured diabetes self management education programme designed to support those with type 2 diabetes self care and prevent long term associated complications.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Type 2 Live Well (structured diabetes self management education programme)
Description: Structured diabetes self management education programme designed to support those with type 2 diabetes self care and prevent long term associated complications.
Study: NCT06642870

Intervention type: OTHER
Intervention: Non-interventional study
Description: The study will consist of focus groups and a large scale patient survey
Study: NCT06248177

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: Probiotic capsules

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: Probiotic capsules

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo capsules

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo capsules
Study: NCT06692699

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Single vision spectacle lens
Description: Standard single vision spectacle lens

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A.R.R.E.S.T. spectacle film
Description: A.R.R.E.S.T. spectacle film
Study: NCT06693505

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: caffeinated chewing gum
Description: two pieces of caffeinated chewing gum at an absolute dose of 200 mg (Military Energy Gum®, Ford Gum and Machine Go, Akron, NY, USA)

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: two pieces of similar looking and tasting placebo gum that did not contain caffeine (xylitol, lime mint, green; Lotte, Saitama, Japan) (PLA trial)
Study: NCT06693440

Intervention type: DRUG
Intervention: PD-1 Inhibitors
Description: Patients received PD-1 inhibitors mono- or combined therapy in real-world clinical practice

Intervention type: DRUG
Intervention: PD-1 Inhibitors
Description: Patients received PD-1 inhibitors mono- or combined therapy in real-world clinical practice
Study: NCT06693180

Intervention type: OTHER
Intervention: HBOT
Description: Hyperbaric Oxygen Therapy