TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06380491

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin 3 MG Oral Tablet
Description: Participants with OSA and nocturnal non-dipping Blood Pressure will be randomly assigned to a treatment with melatonin 3mg/d or to receive only the usual care.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin 3 MG Oral Tablet
Description: Participants with OSA and nocturnal non-dipping Blood Pressure will be randomly assigned to a treatment with melatonin 3mg/d or to receive only the usual care.
Study: NCT05642403

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: XW001
Description: Inhaled XW001

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: XW001
Description: Inhaled XW001

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched inhaled placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched inhaled placebo
Study: NCT04894266

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apabetalone
Description: Apabetalone 100mg BID

Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care
Description: Standard of Care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of care
Description: Standard of Care
Study: NCT05279755

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: prosetin
Description: oral solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: oral solution
Study: NCT04642092

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PsicAP protocol
Description: The intervention will include: psychoeducation, relaxation and breathing techniques, thought management, tips to improve quality of life and relapse prevention. All of these activities will be based on scientific evidence and many of these aspects will be supported by mobile devices.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Typical treatment that is currently given to patients with emotional disorders in Dominican primary care units.
Study: NCT05405803

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-App based Lifestyle Physical Activity Promotion Program
Description: WPAPP-K includes group and individual coaching/support by health care providers, peer coaching/support, and information to change the women's attitudes, self-efficacy, perceived barriers, and social influences.~The program includes 3 components in 2 languages (English and Korean):~1. Social media sites: allow participants to share their experiences and to receive individual and group coaching/ support from culturally matched peers and healthcare providers.~2. Interactive online educational sessions: information on 15 topics related to depressive symptoms and lifestyle physical activity.~3. Online Resources: include 20 links in English or Korean (only from scientific authorities including NIH, CDC,etc.).~Weekly group coaching and support will start after the first 10 participants are enrolled, but individual coaching/support will start as soon as a participant enrolls.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: The Centers for Disease Control and Prevention (CDC) website on depression and physical activity guidelines
Description: A link to the CDC website will be provided through the project website, and participants will be asked to use it during the study period (12 months). Their use of the CDC website will be automatically measured through the project website.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Centers for Disease Control and Prevention (CDC) website on depression and physical activity guidelines
Description: A link to the CDC website will be provided through the project website, and participants will be asked to use it during the study period (12 months). Their use of the CDC website will be automatically measured through the project website.
Study: NCT05621434

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inetetamab, pyrotinib, chemotherapy
Description: Inetetamab: was administered as an intravenous (IV) loading dose of 8mg/kg q3w on Day 1 of Cycle 1 (1 Cycle length = 21 days), and 6mg/kg q3w on Day 1 of subsequent cycles, until investigator-assessed radiographic or clinical progressive disease, unmanageable toxicity, or study termination.~pyrotinib: 400 mg once daily orally within 30 minutes after a meal at the same time each day.~chemotherapy:Taxanes (paclitaxel, docetaxel, liposomal paclitaxel, nabpaclitaxel), vinorelbine, capecitabine, eribulin, and other chemotherapeutic agents indicated in advanced breast cancer are permitted. Refer to the appropriate package insert for dosage and administration recommendations.
Study: NCT05313555

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultraviolet Light (UV-B)
Description: This control group will receive a UV-B exposure as a positive control. Participants will have punch biopsies after exposure.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultraviolet lights (UV-C)
Description: Violet is tabletop device that emits filtered UV-C (200nm-230nm; peak at 222nm). Participants will choose, based on availability, to be in groups that deliver 1 cycle, 10 cycles, 15 cycles or 25 cycles of the Violet. The subject will be exposed for no more than 5 minutes and 20 seconds in total. Participants will have punch biopsies after exposure.
Study: NCT04805190

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Intervention
Description: This intervention comprises three components: 1) general education about pain (e.g., pain pathways) and a rationale for the intervention (e.g., gate control theory); 2) impact of positive and negative pain-related thoughts on neural process of pain; and 3) a guided imaginal pain exposure exercise.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Education
Description: General information about the neurobiology of pain and knee osteoarthritis will be given to participants assigned to this intervention.
Study: NCT06153953

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: vacuum device
Description: use of vacuum device in dressing of diabetic wounds

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional dressing therapy
Description: us of conventional dressing with betadine and iruxol in diabetic wounds
Study: NCT05049954

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calorie-Restricted Healthy Ketogenic Diet
Description: Participants in the experimental group will be advised on a Calorie-restricted Healthy Ketogenic Diet via 7 workshops. Participants will also be advised to monitor their urinary ketones to track compliance.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Calorie-Restricted Low Fat Diet
Description: Participants will be advised on Calorie-restricted Low Fat diet via 7 workshops.
Study: NCT06434454

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EFT Group:Emotional Free Technıcal
Description: The young individuals in the intervention group will be informed about the study, including its purpose and methodology, and their consent will be obtained. Emotional Freedom Techniques (EFT) will be applied to groups of 20 individuals to improve sleep quality, and all scales will be administered beforehand. EFT will be applied twice, with a 15-day interval between sessions, and the same scale questionnaires will be administered again after the second EFT session. Subsequently, the analysis will be conducted.
Study: NCT05333770

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High-frequency repetitive transcranial magnetic stimulation
Description: TMS is an investigational device that provides a way to test the function of a specific part of the brain that is devoted to moving my affected upper limbs by directing a low electrical current to that part of the brain through the scalp.
Study: NCT04553250

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Doubled-stapled colorectal anastomosis
Description: Anastomosis performed between the colon an the rectal stump, using a double-stapled technique.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Doubled-stapled colorectal anastomosis
Description: Anastomosis performed between the colon an the rectal stump, using a double-stapled technique.
Study: NCT06020742

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autologous USC mitochondrial oocyte transplantation
Description: Mitochondria are isolated from urine derived stem cells from fresh middle urine of the subjects, and injected into the cytoplasm of mature oocytes together with sperm
Study: NCT05379660

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation
Description: Basing on the theory of traditional Chinese medicine, bilateral Zusanli (ST 36), Shangjuxu (ST 37) and Sanyinjiao (SP 6) are elected as the acupuncture points,the electrode pads with wire are attached to the corresponding acupoints, which are connected with Hwato electric acupuncture treatment instrument,TEAS stimulation uses a dense-dispersed wave with frequencies of 2 and 100 Hz alternating every 3 s, and the intensity 5 \~ 12mA,on the first and second days after surgery, the doctor who is responsible for acupuncture will arrive at the ward in the morning and afternoon to administer TEAS stimulation at the same acupoints for 30 min in the TEAS groups

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation
Description: Basing on the theory of traditional Chinese medicine, bilateral Zusanli (ST 36), Shangjuxu (ST 37) and Sanyinjiao (SP 6) are elected as the acupuncture points,the electrode pads with wire are attached to the corresponding acupoints, which are connected with Hwato electric acupuncture treatment instrument,TEAS stimulation uses a dense-dispersed wave with frequencies of 2 and 100 Hz alternating every 3 s, and the intensity 5 \~ 12mA,on the first and second days after surgery, the doctor who is responsible for acupuncture will arrive at the ward in the morning and afternoon to administer TEAS stimulation at the same acupoints for 30 min in the TEAS groups

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation
Description: Basing on the theory of traditional Chinese medicine, bilateral Zusanli (ST 36), Shangjuxu (ST 37) and Sanyinjiao (SP 6) are elected as the acupuncture points,the electrode pads with wire are attached to the corresponding acupoints, which are connected with Hwato electric acupuncture treatment instrument,TEAS stimulation uses a dense-dispersed wave with frequencies of 2 and 100 Hz alternating every 3 s, and the intensity 5 \~ 12mA,on the first and second days after surgery, the doctor who is responsible for acupuncture will arrive at the ward in the morning and afternoon to administer TEAS stimulation at the same acupoints for 30 min in the TEAS groups
Study: NCT05057845

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Tislelizumab will be initiated on day 14 after cryoablation. Tislelizumab will be administered at 200 mg i.v. every 3 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lenvatinib
Description: Lenvatinib will be initiated on day 14 after cryoablation. Lenvatinib will be administered (bodyweight ≥ 60 kg, 12 mg; \< 60 kg, 8 mg) orally daily every 3 weeks until documented disease progression, development of unacceptable toxicity, participant request, or withdrawal of consent.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: US/CT-guided Percutaneous Cryoablation
Description: Cryoablation will be performed with a two-cycle freeze-thaw phase protocol; US or non-contrast CT images will be obtained to visualize the evolving ablation zone
Study: NCT06218147

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition-behavior lifestyle program
Description: The 15 participants randomized to the intervention group will complete the activities described in the arm/group description.
Study: NCT05973435

Intervention type: OTHER
Intervention: Blood sampling
Description: Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).

Intervention type: OTHER
Intervention: Blood sampling
Description: Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).
Study: NCT04819984

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TCM5 device (Radiometer) for PtC02 continuous measurement
Description: Evaluation of PtC02 variation as a reflect of PaC02 during 30 minutes of weaning proof for mechanical ventilation (spontaneous ventilation on T-piece)
Study: NCT04869423

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dog-Assisted Therapy
Description: During seven weeks patients will assist one time per week (1 hour). The therapy will be conducted by an expert psychologist. The intervention will consist of 7 weeks conducted once a week (50 minutes each session). It will include three parts: 1) a welcome part aimed to get in touch with the dog, 2) a main part, where participants will be taught basic notions about dog training and then try to train the dogs. In this part, the patients will perform different activities and exercises with the dog. 3) A closing part to say goodbye to the dogs.
Study: NCT04891822

Intervention type: PROCEDURE
Intervention: ERAS protocol
Description: E: ERAS protocol C: control
Study: NCT05085236

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fu's subcutaneous needling (FSN)
Description: physician will use a disposable Fu's subcutaneous needling (FSN) to penetrate the subject's skin in the middle from elbow lateral epicondyle to radial styloid process. Then physician will push forward the needle parallel to the skin surface. the physician will sway the needle 100 times in a minute. After procedure of swaying needle, the physician will instruct subject to do several movements, and each movement will perform 10 seconds and rest 10 seconds for 3 repetitions. The movements are active isometric elbow flexion, active isometric shoulder internal rotation, passive shoulder external and internal rotation. After above re-perfusion approach of muscles, the physician will take out the needle to finish the treatment.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Rehabilitation mentioned here is the regular rehabilitation programs for treating post-stroke hemiplegic shoulder pain prescribed by the rehabilitation physician.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation
Description: Rehabilitation mentioned here is the regular rehabilitation programs for treating post-stroke hemiplegic shoulder pain prescribed by the rehabilitation physician.
Study: NCT05802680

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial photobiomodulation
Description: Administration of Sham or 1064 (+/- 50) nanometers tPBM
Study: NCT06177496

Intervention type: PROCEDURE
Intervention: local ablation
Description: treatment of HCC

Intervention type: PROCEDURE
Intervention: TACE
Description: treatment of HCC
Study: NCT05802680

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial photobiomodulation
Description: Administration of Sham or 1064 (+/- 50) nanometers tPBM

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial photobiomodulation
Description: Sham treatment

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial photobiomodulation
Description: Sham treatment
Study: NCT05780554

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Post transplant cyclophosphamide 25 mg/kg on day +3 and +4

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide
Description: Post transplant cyclophosphamide 50 mg/kg on day +3 and +4
Study: NCT05560971

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Palmitoleic acid
Description: Participants will be randomized to either POA or placebo and will be asked to take 2 capsules of the POA or placebo twice a day for 8 weeks.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Medium chain fatty acids in triglyceride form in capsules with the same shape, color, size and odor of POA capsules
Study: NCT06177496

Intervention type: DRUG
Intervention: Sorafenib
Description: treatment of HCC
Study: NCT06035679

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib and Trastuzumab
Description: Small and large molecules combined with chemotherapy for neoadjuvant treatment of HER2-positive breast cancer
Study: NCT04753970

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cilostazol
Description: Cilostazol 100mg BID
Study: NCT05941767

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine nebulization
Description: The patient will receive nebulized dexmedetomidine via face mask nebulizer 10 minutes before induction of general anesthesia.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine nebulization
Description: The patient will receive nebulized lidocaine 4% (3 mg /kg) 10 minutes before induction of general anesthesia.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine IV
Description: The patient will receive intravenous infusion via a syringe pump of dexmedetomidine (1 ml= 4mcg) started at a dose of 1 mcg/kg 20 minutes before induction of general anesthesia.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine IV
Description: The patient will receive 1.5 mg/kg lidocaine 2% (1 ml = 20mg) completed to 10 ml with normal saline 0.9% intravenous 90 seconds before induction of general anesthesia.
Study: NCT04734691

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PIPAC
Description: PIPAC is a laparoscopic procedure for intraperitoneal administration of chemotherapy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PIPAC
Description: PIPAC is a laparoscopic procedure for intraperitoneal administration of chemotherapy
Study: NCT04634825

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Enoblituzumab
Description: Anti-B7-H3 antibody

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Enoblituzumab
Description: Anti-B7-H3 antibody

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Retifanlimab
Description: Anti-PD-1 antibody

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tebotelimab
Description: PD-1 X LAG-3 bispecific DART molecule
Study: NCT06215430

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caffeine Tablet
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caffeine Tablet
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole capsule
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole capsule
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Warfarin tablet
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Warfarin tablet
Description: Administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LOXO-305
Description: Administered orally.
Study: NCT06144177

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dark with star projector
Description: When in the operating room prior to the start of induction, the room will be darkened, and a star projector that lights up the ceiling and walls will be turned on.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Preoperative midazolam
Description: Midazolam by mouth preoperatively.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Parental Presence
Description: A parent or guardian will accompany the child into the OR and be present for the start of induction.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Parental Presence
Description: A parent or guardian will accompany the child into the OR and be present for the start of induction.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Parental Presence
Description: A parent or guardian will accompany the child into the OR and be present for the start of induction.
Study: NCT05766813

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenrispodun
Description: Lenrispodun 30 mg tablets administered orally, once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching tablets administered orally, once daily.
Study: NCT02703597

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Surveys
Description: Surveys include questions related to tobacco use behavior and attitude toward tobacco, as well as demographic and personality questions. Psychosocial surveys and social network surveys are also completed to capture adolescents' network of friends and opinion leaders.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Surveys
Description: Surveys include questions related to tobacco use behavior and attitude toward tobacco, as well as demographic and personality questions. Psychosocial surveys and social network surveys are also completed to capture adolescents' network of friends and opinion leaders.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ASPIRE
Description: Participants engage in four to five 70-minute sessions of ASPIRE spread over a period of 4 weeks. During ASPIRE use, participants face a screen and individually watch videos and engage in computer-based activities related to the negative effects of tobacco.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GSA-ASPIRE-Network
Description: In groups, participants engage in four to five 70-minute sessions of ASPIRE conducted over a period of 4 weeks. However, during each session, ASPIRE use is coupled with game-based social activities (GSAs). During ASPIRE use, participants watch videos and engage in computer-based activities on the same computer screen. Also, in groups, participants engage in the paper-based GSAs as a team and collaborate as they complete the activities. The GSAs contain games about the effects of tobacco. Groups are allocated based on adolescents' network of friendships.
Study: NCT03629977

Intervention type: DEVICE
Intervention: CRRT
Description: Continuous Renal Replacement Therapy

Intervention type: DEVICE
Intervention: CRRT
Description: Continuous Renal Replacement Therapy

Intervention type: DEVICE
Intervention: CRRT
Description: Continuous Renal Replacement Therapy