TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05488041

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Performing anorectal manometry
Description: Anorectal manometry is a safe, low-risk procedure and is unlikely to cause any pain, colorectal perforation is very rare. Seven cases have been published in four reports.~* Anorectal Manometry - NY Gastroenterology Associates n.d. https://www.gastroenterologistnewyork.com/preparing-for-procedure/anorectal-manometry/ (accessed July 14, 2021).~* Bionda M, Lenglinger J, ... AH-J of E, 2020 undefined. Closure of Large Rectal Iatrogenic Perforation by Endoscopic Suture Device: Go for it. BorisUnibeCh 2020;01:13-5. https://doi.org/10.48350/151165.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Performing anorectal manometry
Description: Anorectal manometry is a safe, low-risk procedure and is unlikely to cause any pain, colorectal perforation is very rare. Seven cases have been published in four reports.~* Anorectal Manometry - NY Gastroenterology Associates n.d. https://www.gastroenterologistnewyork.com/preparing-for-procedure/anorectal-manometry/ (accessed July 14, 2021).~* Bionda M, Lenglinger J, ... AH-J of E, 2020 undefined. Closure of Large Rectal Iatrogenic Perforation by Endoscopic Suture Device: Go for it. BorisUnibeCh 2020;01:13-5. https://doi.org/10.48350/151165.
Study: NCT06147388

Intervention type: DIAGNOSTIC_TEST
Intervention: Colposcopy
Description: No surgery, observation
Study: NCT05985499

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suturing of ileostomy using Dumpling suture method
Description: Suturing of ileostomy using Dumpling suture method

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Suturing of ileostomy using Traditional suture method
Description: Suturing of ileostomy using Traditional suture method
Study: NCT05589857

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IPAD
Description: Participants will play a game using the iPad's standard camera, which will show you your hospital room and the decal/stickers s as they appear in the real world.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Augmented Reality
Description: Participants will play a game through (device camera and application) that add virtual or digital characters and items that let participants view the real world.
Study: NCT05403424

Intervention type: OTHER
Intervention: Evaluation of pain
Description: The severity of pelvic girdle pain will be evaluated with the Visual Analog Scale (VAS).

Intervention type: OTHER
Intervention: Evaluation of pain
Description: The severity of pelvic girdle pain will be evaluated with the Visual Analog Scale (VAS).

Intervention type: DIAGNOSTIC_TEST
Intervention: Application of pelvic girdle diagnostic tests
Description: Pelvic girdle pain diagnostic tests will be applied.

Intervention type: DIAGNOSTIC_TEST
Intervention: Application of pelvic girdle diagnostic tests
Description: Pelvic girdle pain diagnostic tests will be applied.

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of thoracolumbar fascia
Description: The biomechanical and viscoelastic properties of the thoracolumbar fascia will be measured in the prone position and measurements will be taken from three different points

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of thoracolumbar fascia
Description: The biomechanical and viscoelastic properties of the thoracolumbar fascia will be measured in the prone position and measurements will be taken from three different points

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of thoracolumbar fascia
Description: The biomechanical and viscoelastic properties of the thoracolumbar fascia will be measured in the prone position and measurements will be taken from three different points

Intervention type: OTHER
Intervention: Evaluation of activity limitation
Description: Pelvic Girdle Questionnaire will be filled

Intervention type: OTHER
Intervention: Evaluation of activity limitation
Description: Pelvic Girdle Questionnaire will be filled
Study: NCT05849493

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Metacognitive Internet delivered Cognitive Behavior Therapy
Description: Specialist Guided Internet delivered Cognitive Behavior Therapy based on the metacognitive model of excessive worry

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
Description: Specialist Guided Internet delivered Cognitive Behavior Therapy based on the Intolerance of uncertainty model of excessive worry
Study: NCT06655025

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dexmedetomidine
Description: Dexmedetomidine infusion during open heart surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Dexmedetomidine infusion during open heart surgery
Study: NCT06655038

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Advocacy coalition
Description: * set up a task force composed of school stakeholders (students, teachers, educators, principle,...). These stakeholders will meet 4 times a year to improve the implementation and enforcement of TFSP through rules that are accepted, adopted and to which all school actors adhere.~* share of good practices in implementation with the other schools of the intervention arm through a sharing platform and two annual meetings.~* support to reffer nicotine-dependant students and staff members to smoking cessation programs.~* support in the implementation of TFSP and in getting all school actors on board, by the research team, but also by local health promotion partners.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback
Description: Feedback on the basis of the audit and the surveys

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Feedback
Description: Feedback on the basis of the audit and the surveys
Study: NCT06595875

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: m-tapa block
Description: Patients in Group M were placed in the supine position. After skin antisepsis with 5% povidone-iodine, a sterile drape was placed. The high-frequency (8-13 MHz) linear ultrasound (USG) probe was covered with a sterile sheath, and the transversus abdominis, internal oblique, and external oblique muscles were identified at the 10th costal margin in the sagittal plane at the costochondral angle. The probe was angled sagittally to visualize the costochondral angle at the edge of the 10th rib and to display the posterior surface of the rib cartilage in the midline. Using an in-plane technique, a 22-gauge, 100-millimeter (mm) Stimuplex A peripheral nerve block needle was advanced cranially, and the needle tip was directed towards the posterior surface of the 10th costal cartilage. After negative aspiration, 20 mL of 0.25% bupivacaine was injected under the lower surface of the costal cartilage. The same procedure was repeated on the opposite side.
Study: NCT04509726

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EBV-specific TCR-T cell with cytokine auto-secreting element
Description: Patients were pre-conditioned with chemotherapy and infused with EBV-specific TCR-T cells with cytokine auto-secreting element
Study: NCT04842812

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TILs and CAR-TILs targeting HER2, Mesothelin, PSCA, MUC1, Lewis-Y, GPC3, AXL, EGFR, Claudin18.2/6, ROR1, GD1, or B7-H3
Description: TILs and CAR-TILs injection: 1-10×10e7/kg cells for each treatment; 3 or more cycles.
Study: NCT05053646

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Meniscal repair
Description: The meniscus is trimmed with an arthroscopic punch followed by an electric shaver to expose the margins of the tear and remove damaged tissue. Vertical sutures are made using TRUESPAN™ Meniscal Repair System (DePuy Synthes) to approximate both the femoral and tibial surfaces of the torn meniscus.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Meniscal repair
Description: The meniscus is trimmed with an arthroscopic punch followed by an electric shaver to expose the margins of the tear and remove damaged tissue. Vertical sutures are made using TRUESPAN™ Meniscal Repair System (DePuy Synthes) to approximate both the femoral and tibial surfaces of the torn meniscus.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Marrow venting procedure
Description: After meniscal repair, a bone marrow venting procedure will be performed: a 45° micro-fracture awl is repeatedly penetrated through the bone of the intercondylar notch at the PCL origin until marrow elements are seen to enter the joint.
Study: NCT06009211

Intervention type: OTHER
Intervention: QueaseEase
Description: Study participants will participate in one week with aromatherapy treatment and one week without aromatherapy treatment (randomly ordered) to serve as their own control.
Study: NCT05368012

Intervention type: DRUG
Group type: OTHER
Intervention: MIDCAB
Description: Ultrasound-guided administration of the nerve block MIDCAB into mid-calf as analgesic intervention for patients.
Study: NCT06523361

Intervention type: DEVICE
Group type: OTHER
Intervention: H'ability
Description: H'ability is introduced depending the randomization result, during the baseline (before session 4, 5, 6 or 7 with occupational therapist

Intervention type: DEVICE
Group type: OTHER
Intervention: H'ability
Description: H'ability is introduced depending the randomization result, during the baseline (before session 4, 5, 6 or 7 with occupational therapist

Intervention type: DEVICE
Group type: OTHER
Intervention: H'ability
Description: H'ability is introduced depending the randomization result, during the baseline (before session 4, 5, 6 or 7 with occupational therapist

Intervention type: DEVICE
Group type: OTHER
Intervention: H'ability
Description: H'ability is introduced depending the randomization result, during the baseline (before session 4, 5, 6 or 7 with occupational therapist
Study: NCT06522100

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravenous administration of Methylprednisolone
Description: Patients will take intravenous administration of Methylprednisolone (500mg/100ml by IV over 30 minutes per day) for 3 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral Prednisone
Description: After intravenous administration of Methylprednisolone patients will take by oral Prednisone 1mg/kg per day once a day (with a maximum dose of 90 mg per day for patients weighing \> 90kg) for 1 month, followed with a progressive decrease of 10 mg Prednisone every 15 days until a dose of 10mg per day during 15 days (= stop).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Perfusion of placebo
Description: Patients will take perfusion of placebo (G5%: 100ml over 30 minutes per day) for 3 days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oral Prednisone placebo
Description: After the perfusion of placebo, patients will take by oral Prednisone placebo once a day for the same duration as that required if the patient was in the investigational medicinal products group (1 month + progressive decrease).
Study: NCT05024032

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study: NCT06248749

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV iron
Description: Intravenous Iron supplement
Study: NCT04989335

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bisantrene
Description: Combined escalated dose chemotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Combined escalated dose chemotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clofarabine
Description: Combined escalated dose chemotherapy
Study: NCT06172309

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NTQ1062
Description: tablet(s) PO
Study: NCT06328335

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Comprehensive rehabilitation training
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comprehensive rehabilitation training
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rise-bed Training
Description: gradually elevating the bed (head-up tilt) is one of the common methods to treat orthostatic hypotension. This treatment adjusts the patient's bed angle to gradually raise their body, promoting balanced blood distribution throughout the body and reducing orthostatic hypotension symptoms.~In head-up tilt treatment, the bed angle is usually gradually increased from a horizontal position, and the specific angle can be determined based on the patient's condition and tolerance. This treatment process is generally monitored and controlled by medical personnel to ensure safety and effectiveness.~The mechanism of head-up tilt treatment is to increase venous return by changing the body position and increasing the effect of gravity, thereby increasing cardiac preload, output, and blood pressure. This helps to reduce orthostatic hypotension symptoms such as dizziness, lightheadedness, and fatigue.
Study: NCT05779540

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Safeback SBX
Description: The intervention consists in the test of the active device.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham device
Description: The intervention consists in a similar device to that emits same noise but does not deliver airflow.
Study: NCT04983446

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Foralumab
Description: Foralumab is a second generation fully human anti-CD3 antibody

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo will be the vehicle for the foralumab nasal solution without active drug (25 mM sodium acetate/125 mM sodium chloride/0.02% polysorbate 80, pH 5.5 buffer).
Study: NCT05442788

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HB0017 150mg or matching placebo
Description: Each subject receive injection at week0(Day1), week 3(Day22), week 6(Day43) and week 9(Day64), respectively.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HB0017 300mg or matching placebo
Description: Each subject receive injection at week0(Day1), week 3(Day22), week 6(Day43) and week 9(Day64), respectively.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HB0017 450mg or matching placebo
Description: Each subject receive injection at week0(Day1), week 3(Day22), week 6(Day43) and week 9(Day64), respectively.
Study: NCT06169059

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JLP-2004
Description: administration of JLP-2004(COX-2 inhibitor)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JLP-2004
Description: administration of JLP-2004(COX-2 inhibitor)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JC-013
Description: administration of JC-013(COX-2 inhibitor))

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JC-013
Description: administration of JC-013(COX-2 inhibitor))
Study: NCT05411315

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Restricted-use of arterial catheter
Description: The investigator will restrict the use of arterial catheters unless exclusion criteria is met.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard-use of arterial catheter
Description: The investigator will allow standard-use of arterial catheters
Study: NCT05505617

Intervention type: OTHER
Intervention: Single-breath nitric oxide lung diffusing capacity measurements according to type of device in random order.
Description: Device: Jaeger Masterscreen TM (PFT Pro, Vyaire, Hoechberg, Germany)~Device: HypAir Medisoft (Medisoft, Dinant, Belgium)
Study: NCT05868616

Intervention type: DEVICE
Intervention: Cardiac Resynchronization Therapy (CRT)
Description: Cardiac resynchronization therapy (CRT) is a modality of cardiac pacing used in patients with left ventricular (LV) systolic dysfunction and dyssynchronous ventricular activation that provides simultaneous or nearly simultaneous electrical activation of the LV and right ventricle (RV) via stimulation of the LV and RV (biventricular pacing) or LV alone.

Intervention type: DEVICE
Intervention: Cardiac Resynchronization Therapy (CRT)
Description: Cardiac resynchronization therapy (CRT) is a modality of cardiac pacing used in patients with left ventricular (LV) systolic dysfunction and dyssynchronous ventricular activation that provides simultaneous or nearly simultaneous electrical activation of the LV and right ventricle (RV) via stimulation of the LV and RV (biventricular pacing) or LV alone.
Study: NCT06030024

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: repetitive Transcranial Magnetic Stimulation
Description: Magnetic pulses delivered to the Fz area of the brain in a low frequency (1 Hz) manner.
Study: NCT04632836

Intervention type: OTHER
Intervention: quality of life questionnaires
Description: responses for quality of life questionnaires (WHOQOL-BREF questionnaire, study specific questionnaire, PSQI index, HADS scale)

Intervention type: OTHER
Intervention: quality of life questionnaires
Description: responses for quality of life questionnaires (WHOQOL-BREF questionnaire, study specific questionnaire, PSQI index, HADS scale)

Intervention type: OTHER
Intervention: quality of life questionnaires
Description: responses for quality of life questionnaires (WHOQOL-BREF questionnaire, study specific questionnaire, PSQI index, HADS scale)
Study: NCT06073561

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: learning curve of Underwater mucosectomy
Description: Patients will be submitted to underwater mucosectomy (U-EMR)
Study: NCT06519474

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Theraband chest compression
Description: Chest compression applicated via a Red Theraband over the upper or lower chest region

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Theraband chest compression
Description: Chest compression applicated via a Red Theraband over the upper or lower chest region
Study: NCT05606432

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instructor-led, one-on-one M2M exercise group
Description: Participants will attend 3 exercise sessions per week for 24 weeks. Each session will last 15 - 40 minutes. Increasing by 5 - 10 minutes each week. Each session will last from 25 to 50 minutes by increasing 5 to 10 minutes each week. The exercise program will focus on improving cardiorespiratory fitness using a series of movement patterns accompanied by music. The program will be tailored to individuals' abilities (e.g., use of arms only vs. truck movement together; slow vs. fast tempo music). The exercise will be prescribed at a moderate intensity level (working somewhat hard with increased heart rate and breathing rate). For the follow-up phase (weeks 25-36), participants will receive the recorded M2M exercise sessions between the M2M instructors and themselves to continue to exercise for the remaining 12 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self-guided control with pre-recorded standard exercise videos
Description: Participants will exercise for 36 weeks using pre-recorded exercise videos. The videos include warm-up, flexibility, muscular strength, aerobic endurance, balance, and cool-down.
Study: NCT06519708

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block
Description: Patients will receive an ultrasound-guided erector spinae plane block with the injection of 30 ml bupivacaine 0.25% after induction of general anesthesia.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: External Oblique Intercostal Plane Block
Description: Patients will receive an ultrasound-guided external oblique intercostal plan block Intraoperative with the injection of 30 ml bupivacaine 0.25% after induction of general anesthesia.
Study: NCT05848999

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UCLM802 Cell Injection (Anti-mesothelin CAR-T cells)
Description: D0: 0.1×106/Kg ～ 2.0×106/Kg; Cells will be infused intravenously.
Study: NCT06103786

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Assigned Interventions
Description: Ice hockey players did 12 weeks of on-ice high-intensity interval training. Their training included:~Repetitive sprint training Sprint interval training Long-pass tracking drills Chase-the-rabbit tracking drills High-intensity interval training in four types improved college ice hockey players' sports performance in 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Random Interventions
Description: Ice hockey players did 12 weeks of traditional on-ice training. Their training included:~Varied pacing skating Dribbling and shooting Passing and catching drills 2-on-1 offensive tactics Traditional training in four types improved college ice hockey players' sports performance in 12 weeks.~A 12-week on-ice training program was conducted on college players to observe its effects on their physical fitness, skills, and tactical performance compared to an experimental and control group.
Study: NCT05928962

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human Adenovirus Type 5 Injection
Description: 1. Recombinant Human Type 5 Adenovirus Injection:~   This is expected to be administered prior to immunotherapy, i.e. scheduled for injection at C1D1 (C2D1, C3D1, C4D1). 1 treatment period every 2 weeks (3 day window) for a total of 4 cycles.~2. PD1 monoclonal antibody (Tremelimumab):~Administered intravenously within 48h of recombinant human adenovirus type 5 injection, scheduled at C1D2 (C2D2, C3D2, C4D2). 1 treatment period every 2 weeks (3 day window) for a total of 4 cycles.
Study: NCT05876000

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Corheart 6 Left Ventricular Assist System
Description: Implantation of left ventricular assist device for mechanical circulatory support
Study: NCT06067217

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid 250 mg oral tablet
Description: Compare between tranexamic acid and progynova to stop abnormal uterine bleeding in DMPA users

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Progynova 1 mg oral tablet
Description: Compare between tranexamic acid and progynova to stop abnormal uterine bleeding in DMPA users
Study: NCT06219408

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CIH Stepped Care
Description: A mindfulness-based and meaning-based stepped care approach for treating co-occurring chronic pain and PTSD that will begin with less intensive treatment (e.g., psychoeducation) and, based on patient response and preference, will be stepped up to more intensive treatment when appropriate.