TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06552611

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical spinal cord stimulation + therapy
Description: A two-channel transcutaneous spinal cord stimulator (SCONE, SpineX, Inc.) will deliver non-invasive electrical stimulation during hand therapy sessions. For each session, two self-adhesive hydrogel electrodes will be positioned along the midline of the C3-C4 and C6-C7 spinous processes over the skin as cathodes to stimulate the cervical spinal cord at two vertebral levels. An additional pair of electrodes will be symmetrically positioned over either the iliac crests or shoulders, functioning as anodes. The electrical current employed for the transcutaneous spinal cord stimulation is biphasic, featuring a 1-millisecond pulse width, a base frequency of 30 Hz, and an overlapping frequency of 10 kHz. Stimulation intensity will range from 0 to 120 milliamperes (mA), with incremental increases of 5 mA until reaching the level that facilitates voluntary movement. The stimulation amplitude will be fine-tuned for each specific activity based on the therapist's observation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Occupational Therapy
Description: The hand therapy program is comprised of intensive, progressive, functional task practice following a standardized protocol. The protocol consists of repetitive activities of gross upper limb movement, isolated finger movements, bimanual task performance, simple and complex pinch, and grip performance. Several activities with various difficulty levels are designated for each category, and the participant will perform 1-2 activities within each category in each training session. Activities are chosen according to the participant's ability, interests, and needs and are modified as function progresses over time.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Occupational Therapy
Description: The hand therapy program is comprised of intensive, progressive, functional task practice following a standardized protocol. The protocol consists of repetitive activities of gross upper limb movement, isolated finger movements, bimanual task performance, simple and complex pinch, and grip performance. Several activities with various difficulty levels are designated for each category, and the participant will perform 1-2 activities within each category in each training session. Activities are chosen according to the participant's ability, interests, and needs and are modified as function progresses over time.
Study: NCT04980976

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Blind insertion technique
Description: Transesophageal echocardiography probe will be inserted using a conventional blind insertion technique.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: C-MAC videolaryngoscope insertion technique
Description: Transesophageal echocardiography probe will be inserted using a C-MAC videolaryngoscope insertion technique
Study: NCT05041452

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance scan
Description: Multiparametric cardiac magnetic resonance, including functional and structural parameters

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance scan
Description: Multiparametric cardiac magnetic resonance, including functional and structural parameters
Study: NCT05912855

Intervention type: DEVICE
Intervention: qNOX
Description: Non
Study: NCT05022134

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CHOICE-AYA
Description: Adapted contraceptive counseling specific to AYA experiencing homelessness
Study: NCT05605912

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants perform five one-hour conventional training sessions at the Sint Maartenskliniek in which they perform functional exercises. After the conventional training program, the control group will receive a recommendation for physical activity at home for six weeks.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Myosuit
Description: Participants perform five one-hour Myosuit training sessions at the Sint Maartenskliniek in which they perform functional exercises and learn to don, doff and use the device for standing, walking, climbing the stairs and sit-to-stand transitions. After the clinical Myosuit training program, participants receive the Myosuit at their disposal at home and a recommendation for physical activity at home for six weeks.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Myosuit
Description: Participants perform five one-hour Myosuit training sessions at the Sint Maartenskliniek in which they perform functional exercises and learn to don, doff and use the device for standing, walking, climbing the stairs and sit-to-stand transitions. After the clinical Myosuit training program, participants receive the Myosuit at their disposal at home and a recommendation for physical activity at home for six weeks.
Study: NCT05854459

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HIIT and Nordic Curl exercise program
Description: The training program in the HIIT+NC group was divided into the following parts: i) warm-up (10 minutes); ii) HIIT (25 minutes) consisting of a circuit of eight exercises; iii) Nordic curl exercise (10 mintues); and iv) stretching.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: HIIT-only program
Description: The HIIT group performed the same exercises in the warm-up, HIIT and stretching sections as the HIIT+NC group, however, they did not perform the NC eccentric exercises.
Study: NCT05918757

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Protein dose 1.5 g/kg/day
Description: Administration of 1.5 g of protein/kg/day via enteral/parenteral nutrition

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Protein dose 1.0 g/kg/day
Description: Administration of 1.0 g of protein/kg/day via enteral/parenteral nutrition
Study: NCT05735964

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine green
Description: Intravenous and endoluminal dosing
Study: NCT06285097

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sasanlimab
Description: A monoclonal antibody that blocks the interaction between PD-1 and PD-L1/L2

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sasanlimab
Description: A monoclonal antibody that blocks the interaction between PD-1 and PD-L1/L2
Study: NCT06524700

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pectopexy mesh
Description: pectopexy with mesh

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pectopexy autologous
Description: pectopexy using autologous graft
Study: NCT05799261

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Control (standard protocol)
Description: The control group will be treated according to standard protocols of the Department of Periodontology of the university of Bern and receive conventional scaling and root planing. Supra- and subgingival hard and soft tissue deposits are being removed by means of hand instruments and ultra-sonic scalers followed by rubber cup polishing. All patients will have 2 visits per year. At each visit outcome measures will be assessed by masked dentists.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Test (Guided Biofilm management)
Description: The test group will be treated according to a novel treatment concept (Guided biofilm management, GBM):~1. Staining of all tooth surfaces to detect soft and hard deposits.~2. Removal of supra- and subgingival hard and soft bacterial deposits by means of an erythritol powder air-polishing.~3. If present, the supra- and subgingival hard deposits (e.g. calculus) will be removed by means of a slim ultrasonic tip (Piezon PS, EMS, Nyon Switzerland) without any additional use of hand instruments.~4. Another sub- and supragingival application of erythritol powder air-polishing without any rubber cup polishing. All patients will have 2 visits per year. At each visit outcome measures will be assessed by masked dentists.
Study: NCT06461624

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-GPC3 CAR-T
Description: All subjects were intravenous administrated with CBG166.
Study: NCT05736497

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Care Plans
Description: Investigators will develop digital care plans for 10 common Cancer Predisposition Syndromes for patients diagnosed within 3 years.
Study: NCT05370430

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BAFFR-CAR T cells
Description: First-in-human trial examining the safety and preliminary efficacy of BAFFR-CAR T cells in participants with r/r B-NHL
Study: NCT04681079

Intervention type: DRUG
Intervention: albuterol sulfate (MDI)
Description: albuterol sulfate inhalation aerosol delivered via metered-dose inhaler (MDI) with spacer

Intervention type: DRUG
Intervention: albuterol sulfate (MDI)
Description: albuterol sulfate inhalation aerosol delivered via metered-dose inhaler (MDI) with spacer

Intervention type: DRUG
Intervention: albuterol sulfate (nebulizer)
Description: albuterol sulfate inhalation aerosol delivered via nebulizer with filtered mouthpiece

Intervention type: DRUG
Intervention: albuterol sulfate (nebulizer)
Description: albuterol sulfate inhalation aerosol delivered via nebulizer with filtered mouthpiece
Study: NCT05216692

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: La Tour Hospital Foot Strengthening Protocol
Description: First exercise : NMES forward lean doming. Doming exercise assisted by NMES placed on the IFM. 8 sec of contraction (6 sec rest) moving the trunk forward. 12 repetitions, 3 sets. Progressive increase of the intensity of NEMS during 4 weeks and increase of body load while decreasing the number of repetitions.~Second exercise : MTP joint flexion. Isometric MTP joint flexion contractions. 4 contractions of 5 sec (10 sec rest), 3 sets. Progressive increase of the number of MVIC during 4 weeks and of increase body load while keeping the same intensity.~Third exercise : Foot-ankle rebound. Multiple jumps with only plantar flexion. Keeping the knee stiff and straight and pushing off the ground with only ankle and MTP plantar flexion by a forefoot contact with the ground. 10 seconds of jump (1 min of rest) during 5 sets. Progressive increase of body load while keeping the same intensity.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Literature Foot Strengthening Protocol
Description: During the 1st week, the participants will perform the Short foot exercise (SFE) during 3 series of 10 repetitions of 5 seconds of contractions in sitting position. 1 minute of rest will be give between series.~During the 2nd week, the participants will perform the SFE during 3 series of 15 repetitions of 5 seconds of contractions in sitting position. 1 minute of rest will be give between series.~During the 3rd week, the participants will perform the SFE during 3 series of 15 repetitions of 5 seconds of contractions in standing bipedal position. 1 minute of rest will be give between series.~During the 4th week, the participants will perform the SFE during 3 series of 15 repetitions of 5 seconds of contractions in standing unipedal position. 1 minute of rest will be give between series.~The progression of the exercise during the protocol will be based on passing from a sitting position to a unipedal standing position.
Study: NCT06396611

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Training as Intervention
Description: Supervised Exercise Training as an Intervention using Resistance Training.
Study: NCT05215925

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX07+carboplatin+pemetrexed
Description: HLX07 1500mg q3w+carboplatin+pemetrexed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX07+docetaxel
Description: HLX07 1500mg q3w+docetaxel

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX07
Description: HLX07 1500mg q3w
Study: NCT06324240

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaccine Therapy
Description: Given TMV vaccine ID

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaccine Therapy
Description: Given TMV vaccine ID

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaccine Therapy
Description: Given TMV vaccine ID
Study: NCT06087549

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pericapsular nerve group block using 0.2% ropivacaine
Description: Unilateral ultrasound guided pericapsular nerve block using 0.5mL/kg 0.2% Ropimol (max 20mL)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block using 0.2% ropivacaine
Description: Unilateral ultrasound guided erector spinae block using 0.5mL/kg 0.2% Ropimol (max 20mL)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care
Description: No erector spinae block and no pericapsular nerve group block
Study: NCT05133063

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gratitude letter
Description: Participants are given the following instructions:~Think of someone in your life who you feel like you have never fully or properly thanked for something meaningful or important that they did for you. . . . In the space provided below, please write a note to this person that describes why you feel like you never properly thanked them and letting them know why you feel thankful for something important that they did for you. Though this letter will not actually be sent to this person and is simply an exercise for you, please use this as an opportunity to really explore those feelings surrounding how you feel about what they have done for you and write honestly and openly from your heart. You have ten minutes.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control intervention
Description: Participants receive the following instructions:~Think of the room you are in.... In the space below, please provide a description of the room you are in. Try to focus on the specific elements in the room, the colours of the wall or objects in the room. Use this writing session as an opportunity to paint a detailed picture of this room and include as much specific information as you can. You have ten minutes.
Study: NCT06500962

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Participants will receive a message sent to their electronic health record portal with instructions about how to sign up for a food is medicine program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Participants will receive a message sent to their electronic health record portal with instructions about how to sign up for a food is medicine program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Participants will receive a message sent to their electronic health record portal with instructions about how to sign up for a food is medicine program.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: Participants will receive a message sent to their electronic health record portal with instructions about how to sign up for a food is medicine program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Navigation
Description: Participants will receive a weekly phone call from a navigator to promote enrollment in the food is medicine program and address any barriers to participation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Navigation
Description: Participants will receive a weekly phone call from a navigator to promote enrollment in the food is medicine program and address any barriers to participation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text Messaging
Description: Participants will receive two text messages per week to promote healthy eating, enrolling in a food is medicine program, and continuing to participate in a food is medicine program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text Messaging
Description: Participants will receive two text messages per week to promote healthy eating, enrolling in a food is medicine program, and continuing to participate in a food is medicine program.
Study: NCT01522092

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: escitalopram
Description: 5mg-20mg, tablet, od, 12 months
Study: NCT05783726

Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: Participants will be shown images of juice, bread, yogurt, cookies, and cereal without any added front-of-package labels.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutriscore Label
Description: A front-of-package Nutriscore label will be applied to images of juice, bread, yogurt, cookies, and cereal. This label applies a score of A, B, C, D, or E based on the product's nutrition profile.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adapted Peruvian Nutrient Label
Description: A front-of-package octagonal nutrient label will be applied to images of juice, bread, yogurt, cookies, and cereal. The label text informs consumers if a product is high in sugar, saturated fat, or salt/sodium. These labels were developed by the Peruvian government and adapted by investigators.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guideline Daily Amount Label
Description: A front-of-package Guideline Daily Amount label will be applied to images of juice, bread, yogurt, cookies, and cereal. The label shows the amount and percent of daily value of calories, total fat, saturated fat, sugar, and sodium in one serving of a product.
Study: NCT05960019

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fermented milk product
Description: This is a type of cultured bovine milk, that is prepared through mesophilic fermentation of milk, that is widely available in Kenya. Participants will be expected to consume 250ml of the mala each day for breakfast.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fermented cereal based product
Description: This is a fermented cereal-based porridge prepared from a mix of ground millet and sorghum that is mixed with water into a gruel which is fermented into a non-alcoholic beverage or meal depending on desired thickness. Participants will be expected to consume 250ml of the porridge each day for breakfast.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioural modification counselling
Description: Standard of care shall comprise behavioural (lifestyle) modification counselling delivered monthly. This shall consist of provision of counselling on lifestyle modification in an effort to help the patients prevent progression of the pre-diabetes and provide help with any emerging complications of the disease. Counselling on lifestyle modification shall comprise provision of standard dietary and exercise advice for pre-diabetics by a study doctor.
Study: NCT06423157

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention
Description: The intervention period will last 6 weeks, with a periodicity of 2 weekly sessions of 20 minutes each. All interventions will take place at the Palacio de los Deportes de Murcia. All interventions will be carried out by the same physiotherapist, following the same protocol. The intervention of the experimental group will consist of a protocol using plyometric and stability exercises.
Study: NCT04748237

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Coronary computed tomopraphic angiography
Description: CCTA as soon as possible, preferably within 24 hours, but not later than within 21 days.
Study: NCT05206500

Intervention type: DRUG
Group type: OTHER
Intervention: Antibiotic
Description: FDA approved and marketed antibiotic treatment for the patients with UTI symptoms and CC \>0 and \<10,000

Intervention type: DEVICE
Group type: OTHER
Intervention: Next Gen
Description: Next Generation Sequencing (NGS) is available to detect bacteria in urine based on bacterial genomes.
Study: NCT06014762

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: P-CD19CD20-ALLO1
Description: Single weight-based IV administration

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: P-CD19CD20-ALLO1
Description: Single weight-based IV administration

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: P-CD19CD20-ALLO1
Description: Single weight-based IV administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimiducid
Description: Single weight-based IV administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimiducid
Description: Single weight-based IV administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimiducid
Description: Single weight-based IV administration
Study: NCT05334836

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MRI for pancreatic fat and liver fat quantitation
Description: MR imaging would be performed using a 3.0 T scanner (Achieva X series, Philips Healthcare, Best, The Netherlands) with a 16-channel SENSE-XL-Torso array coil. 3D spoiled chemical-shift water-fat mDixon sequence (TR = 5.7 ms, first TE/echo spacing = 1.2-1.4 (ms)/1.0-1.2 (ms), number of echoes = 6, flip angle = 3°, SENSE acceleration = 2, a breath hold technique would be employed to acquire co-registered water, fat, fat-fraction and T2\* image series and would be reconstructed with slice thickness/number of slices = 3.0 mm/50. The field of view (FOV) covered the upper abdomen, i.e. region from the dome of the diaphragm to the iliac crest covering the entire extent of the liver and pancreas. Image reconstruction would be completed online using Philips mDixon product implementation with the multi-peak spectral model of fat to increase accuracy and sensitivity.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MRI for pancreatic fat and liver fat quantitation
Description: MR imaging would be performed using a 3.0 T scanner (Achieva X series, Philips Healthcare, Best, The Netherlands) with a 16-channel SENSE-XL-Torso array coil. 3D spoiled chemical-shift water-fat mDixon sequence (TR = 5.7 ms, first TE/echo spacing = 1.2-1.4 (ms)/1.0-1.2 (ms), number of echoes = 6, flip angle = 3°, SENSE acceleration = 2, a breath hold technique would be employed to acquire co-registered water, fat, fat-fraction and T2\* image series and would be reconstructed with slice thickness/number of slices = 3.0 mm/50. The field of view (FOV) covered the upper abdomen, i.e. region from the dome of the diaphragm to the iliac crest covering the entire extent of the liver and pancreas. Image reconstruction would be completed online using Philips mDixon product implementation with the multi-peak spectral model of fat to increase accuracy and sensitivity.
Study: NCT06448299

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TAPB
Description: Patients will receive ultrasound guided bilateral oblique subcostal TAPB using 25 mL bupivacaine 0.25% in each side

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: ESPB
Description: Patients will receive ultrasound guided bilateral ESPB at T8 level using 25 mL bupivacaine 0.25% in each side
Study: NCT05454839

Intervention type: OTHER
Intervention: Survey
Description: Interviewer-administered survey

Intervention type: OTHER
Intervention: Focus group
Description: Focus group for selected participants