TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06130384

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Use of bromfenac 0.09% to reduce intravitreal injection pain
Description: The eyedrop (bromfenac) will be given to the assigned eye.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Use of artificial tears to reduce intravitreal injection pain
Description: The eyedrop (artificial tears) will be given to the assigned eye.
Study: NCT04876001

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Behavior Therapy for Insomnia
Description: The BBTI consists of two in-person sessions on week 1 and 3 and two sessions on week 2 and 4 as the booster delivered by phone call.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Behavior Therapy for Insomnia
Description: The BBTI consists of two in-person sessions on week 1 and 3 and two sessions on week 2 and 4 as the booster delivered by phone call.
Study: NCT05693623

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cold application
Description: cold application
Study: NCT05825716

Intervention type: OTHER
Intervention: Ifaa Basic
Description: * PSNP Systems: (1) Provision of food aid commodities (wheat, oil, and pulse) per the PSNP transfer schedule for 3-6 months; 2) Food System Taskforce (FSTF) capacity building, and 3) private sector engagement~* Health and Nutrition: 1) Government of Ethiopia (GoE) basic health extension program; 2) GoE supportive supervision coaching; 3) GoE-led community social behavior change (SBC) sessions; and 4) Community Management of Acute Malnutrition (CMAM) Programming.~* Water and Sanitation: 1) Water infrastructure development; 2) improved governance via water, sanitation and hygiene (WASH) committees; and 3) water source monitoring.~* Natural Resource Management: 1) Public works projects; 2) community training in planning and sustaining community assets; 3) Implementation of the environment and social management framework; 4) enhance participation of watershed committees

Intervention type: BEHAVIORAL
Intervention: Ifaa Enhanced
Description: * PSNP Systems: 1) establishment and training of Community Technical Coordinating Forum; 2) Case management capacity building; and 3) private sector construction of infrastructure~* Health and Nutrition:1) the Care Group Model approach; 2) home garden promotion; 3) the nutrition budget calculator; and 4) labor and time-saving technologies.~* Community-level interventions are 1) adolescent nutrition school clubs; 2) religious leader mobilization and training vulnerable groups; 3) audio toolkit against harmful traditional practice; 4) enhanced SBC tools for health/nutrition promotion; 5) additional health extension programs~* Water and Sanitation: 1) Community Led Total Sanitation and Hygiene; 2) WASH systems assessments and strengthening; 3) Ensuring water quality and safety via routine monitoring; 4) Private sector engagement of WASH-related businesses;

Intervention type: OTHER
Intervention: Ifaa Enhanced + Livelihoods
Description: * Additional resources provided to the groups, including 1) Engagement of Private Service Providers to enable access to sustainable credit and larger loans; 2) Financial Education using an expanded 'Smart Skills' curriculum focusing on savings, smart borrowing and effective financial management; and 3) Life Skills Training for Youth.~* Additional supports include: 1) Seven Steps of Marketing Training; 2) Climate Smart Agriculture to reduce water needs and increase soil health and vegetation coverage; 3) Producers Groups and linkages to markets/suppliers/buyers; Selected financial institutions will be provided with a credit guarantee fund and capacity-building support to help facilitate loans. Private sector value chain assessment and financing. Additional private sector engagement and linkage facilitation.
Study: NCT05322460

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CUMACA-M Program
Description: The CUMACA-M Program will focus on a web-based tailored intervention, using artificial intelligence, for Long-Term Survivors of Breast Cancer. It will be structured into modules related to the specific needs of LS-BS, including physical, psychological, and social needs
Study: NCT05762822

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: 3-OHB (KE4)
Description: 60 ml (30 g) of 3-OHB

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: water
Description: 60 ml water (added bitter taste)
Study: NCT06563388

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stereotactic Ablative Radiotherapy
Description: Radiation therapy begins after 3 months of Standard of care

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stereotactic Ablative Radiotherapy
Description: Radiation therapy begins after 3 months of Standard of care

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stereotactic Ablative Radiotherapy
Description: Radiation therapy begins after 3 months of Standard of care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Practice
Description: Receive standard of care therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Practice
Description: Receive standard of care therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Practice
Description: Receive standard of care therapy
Study: NCT04759911

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selpercatinib
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Therapeutic Conventional Surgery
Description: Undergo standard of care surgery
Study: NCT06366555

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual Acupuncture Twirling,
Description: Manual Acupuncture twirling : using 0.14x 25 mm needle, punctured and penetrated the skin and then a twirling manipulation is carried out, 180 degrees, 3 rad/second, for 30 second each at LU5 and PC2. The needles retained for 20 minutes and manipulated at 0 minutes and 10 minutes.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Manual Acupuncture Sham
Description: Manual Acupuncture Sham : Using 0.14x25mm needles on plesterin without being penetrated into skin and no manipulation given, retained for 20 minutes
Study: NCT06182449

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Distraction
Description: In a private NICU room, mothers will wear a head-mounted VR device when they will initiate the expression of their maternal milk. The video within the VR system will provide a calm forest environment with waterfalls, animals, and birdsong (INSPIRE® Program). The baby may or may not be present in the room during the intervention. This will be documented.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Protocol
Description: Mothers will express their maternal milk in a private room in the NICU with their baby or a photo of the baby. Use of any co-interventions for anxiety management (e.g. music) durign this sequence will be documented.
Study: NCT06253260

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Analgesic Efficacy of Sequential Rapid Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine Injection in Patients Undergoing Unilateral Inguinal Hernia Repair
Description: Analgesic Efficacy of Sequential Rapid Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine Injection in Patients Undergoing Unilateral Inguinal Hernia Repair Surgery
Study: NCT06054620

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Collagen and Vitamin C
Description: Collagen-modelled crystalline amino acids (30g total, 8g glycine) and vitamin C (500 mg).

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Carbohydrate Placebo
Description: Iso-caloric Placebo (30g maltodextrin).
Study: NCT05398874

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Ginkgo biloba extract + standard treatment( paracetamol+Diclofenac100mg SR)
Description: 120 mg leaf extract , twice daily in addition to Diclofenac 100 mg Once daily + paracetamol 1g Twice daily

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: placebo in addition to the standard treatment
Description: placebo in addition to the standard treatment
Study: NCT05887856

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: comprehensive educational program for reduction of Pre-Operative Anxiety
Description: BSEP 1 makes use of modern media and aims to educate patients and their carers through educational videos comprising of various aspect of surgical treatment.~1. Introduction to surgery by consultant surgeon, Patient to receive video of their own surgeon.~2. Introduction to Anesthesia.~3. What are different type of breast surgeries in cancer patients (General Video)~4. Specific video pertaining to the type of surgery patient is undergoing (Mastectomy, Breast Conserving Surgery, Breast Re Construction surgery)~5. Explanation of Methicillin-resistant Staphylococcus aureus Decolonization protocol~6. What to expect on Surgery Day~7. Virtual tour of Holding bay and Operation Room~8. Post-Operative care including wound care, drain management and common post-operative complications.
Study: NCT04706598

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: Solution for Infusion (Intravesical)
Study: NCT05082870

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supportive-expressive group therapy (SEGT)
Description: The SEGT approach fosters mutual support, promotes openness and emotional expression. SEGT will be delivered and co-facilitated by a psychiatrist and an allied healthcare professional. It is a 6-module program held over a 3-week period (approximately 2 hour sessions X 2 week) that is framed within social cognitive theory, whereby resilience to adversity (limb loss in this instance) relies on personal enablement.
Study: NCT04847830

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Er:YAG laser (Waterlase)
Description: The WaterLase iPlus tissue cutting system is a unique device with diverse, hard- and soft-tissue dental applications. It utilizes advanced laser and water atomization technologies to safely and effectively cut, shave, contour, roughen, etch, and resect oral hard-tissue, and direct laser energy to perform oral soft-tissue removal, incision, excision, ablation and coagulation.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: root surface dbridement
Description: root surface debridement under local anaesthesia

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: root surface dbridement
Description: root surface debridement under local anaesthesia
Study: NCT05125042

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Amiodarone hydrochloride tablet + acupoint catgut embedding
Description: Patients with persistent AF after undergoing catheter ablation take receive acupoint catgut embedding in Neiguan and Zusanli twice after and one month after surgery combined with amiodarone hydrochloride tablets 200mg bid, 1 month; 200mg qd,maintained to 3 months.All patients, who had no signs of recurrence three months after surgery, stopped taking medication.
Study: NCT05569577

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Additional hCG injection
Description: An additional hCG injection of 2000-5000IU would be given 48 hours following routine hCG trigger and ovulation for LPS on the basis of supplementation of estrogen and dydrogesterone.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: estrogen and dydrogesterone
Description: estrogen and dydrogesterone

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: estrogen and dydrogesterone
Description: estrogen and dydrogesterone
Study: NCT05632497

Intervention type: BIOLOGICAL
Intervention: Stool and blood samples
Description: Stool and blood samples

Intervention type: BIOLOGICAL
Intervention: Stool and blood samples
Description: Stool and blood samples
Study: NCT06253260

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Analgesic Efficacy of Sequential Slow Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine in Patients Undergoing Unilateral Inguinal Hernia Repair Surgery
Description: Analgesic Efficacy of Sequential Slow Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine in Patients Undergoing Unilateral Inguinal Hernia Repair Surgery
Study: NCT06627075

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surface Guided RadioTherapy (SGRT) without mask
Description: Firstly, patients are positioned in a vacuum mattress that moulds their head, neck and shoulders for a reference scan.~During the treatment sessions, patients are positioned according to the reference scan, using the surface camera system.~Once the observed offsets have been applied, the patient's surface is captured. Treatment can then begin, with continuous monitoring of displacements by the surface camera system. Automatic beam interruption is provided during treatment in the event of motion detection exceeding the standard tolerance threshold (\>3 mm).~If the use of a thermoformed mask during your treatment prove necessary, for whatever reason, will not result in a halt to the research.~Patients receive between 10 and a max of 35 radiotherapy sessions. The follow-up period begins after the last radiotherapy session, and patients are assessed at 4 or 6 weeks and at 3 months by a radiotherapist.
Study: NCT06628232

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pacifier with breast milk
Description: swaddling in the mother\&#39;s lap together with giving a pacifier dipped in breast milk

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: heel heating
Description: swaddling in the mother\&#39;s lap together with local dry heat application
Study: NCT06143579

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOLFOX-HAIC+Lenvatinib+Envolizumab
Description: FOLFOX-HAIC: Oxaliplatin 130 or 85 mg/m2; leucovorin 200 mg/m2; fluorouracil 400 mg/m2 intravenous bolus followed by fluorouracil 2400 mg/m2 continuous infusion over 23 hours, Q3W, 2 to 4 cycles;~Lenvatinib: 8 mg/day (BW \< 60 kg) or 12 mg/day (BW ≥ 60 kg), PO, 3-4 cycles;~Envolizumab: 300 mg, SC, Q3W, 3-4 cycles.
Study: NCT05760456

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DIDALA hard capsules
Description: DIDALA is given orally with a dose of 2 capsules, 3 times per day for 12 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Metformin 500mg, 1 tablet twice a day, immediately after breakfast and dinner for 12 weeks
Study: NCT06337370

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chronic Disease Self Management Program
Description: CDSMP is a group-based chronic disease self-management education intervention comprised of 2.5-hour sessions, including time for a break and snack. The maximum number of participants per session ranges from 12 to 16. In total the program consists of 6 sessions that take place once a week for a total duration of 6 weeks. The development of each of the sessions is standardized and scripted; two group leaders previously trained by a Master Trainer, who in turn was trained to train leaders with Stanford University, guide the sessions. In the case of the present study, the main researcher and a nursing professional with experience in health education will receive the training from a Master Trainer of the program. Participants receive the book Taking Control of Your Health at the beginning of the program.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Care Group
Description: The conventional intervention consists of education provided by the nursing staff when the patient is admitted to the RA Clinical Care Center (C3AR); patients receive a pharmacological and allergy reconciliation form; the C3AR care pathway; an educational pamphlet and a disease diary. The education provided is oriented to the disease, pharmacological treatment, adherence, healthy lifestyles and guidance on administrative procedures. Group educational sessions are held twice a year with patients, family members and caregivers.~Follow-up is carried out either in person, virtually or by telephone to strengthen tools, agree on self-care goals, promote healthy lifestyles, improve adherence and mitigate risks related to the disease and its management at home.
Study: NCT06628232

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: interventions combined
Description: swaddling in the mother\&#39;s lap together with giving a pacifier dipped in breast milk and heel heating

Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: swaddling the baby in the mother\&#39;s lap
Study: NCT06255145

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bioelectrical Impedance Analysis
Description: Bioelectrical Impedance Analysis Beurer BF 1000 Super Precision device was used to measure the body composition of the participants. Operating on the principle of BIA, the device allows the body composition to be evaluated by giving an imperceptible electric current to the body.~Fatigue Severity Scale (FSS) Fatigue Severity Scale (FSS) was used to measure participants' fatigue levels. Rivermead Mobility Index Rivermead Mobility Index (RMI) was used to assess the mobility levels of the participants.~Functional Independence Measure Functional Independence Measure (FIM) was used to evaluate the functional status of the participants.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bioelectrical Impedance Analysis
Description: Bioelectrical Impedance Analysis Beurer BF 1000 Super Precision device was used to measure the body composition of the participants. Operating on the principle of BIA, the device allows the body composition to be evaluated by giving an imperceptible electric current to the body.~Fatigue Severity Scale (FSS) Fatigue Severity Scale (FSS) was used to measure participants' fatigue levels. Rivermead Mobility Index Rivermead Mobility Index (RMI) was used to assess the mobility levels of the participants.~Functional Independence Measure Functional Independence Measure (FIM) was used to evaluate the functional status of the participants.
Study: NCT06722521

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pitavastatin 4mg and ezetimibe 10mg, taken once daily
Description: Intensive lipid-lowering therapy without aspirin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pitavastatin 2 mg with aspirin 100 mg, taken once daily.
Description: Moderate-intensity lipid-lowering therapy with aspirin
Study: NCT06726993

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Total knee arthroplasty
Description: Total knee arthroplasty (TKA) is a common orthopaedic surgery that involves replacing the articular surfaces (femoral condyles and tibial plateau) of the knee joint with smooth metal and highly cross-linked polyethylene plastic

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Total knee arthroplasty
Description: Total knee arthroplasty (TKA) is a common orthopaedic surgery that involves replacing the articular surfaces (femoral condyles and tibial plateau) of the knee joint with smooth metal and highly cross-linked polyethylene plastic
Study: NCT06742736

Intervention type: DRUG
Intervention: BGF
Description: BUDESONIDE/GLYCOPYRRONIUM/FORMOTEROL

Intervention type: DRUG
Intervention: BGF
Description: BUDESONIDE/GLYCOPYRRONIUM/FORMOTEROL

Intervention type: DRUG
Intervention: BGF
Description: BUDESONIDE/GLYCOPYRRONIUM/FORMOTEROL
Study: NCT06742398

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Carbohydrate Dissolvable Strip
Description: Participants are provided with a carbohydrate dissolvable strip for every 12.5% of the time trial that is completed (calculated based on the distance covered).~The carbohydrate dissolvable strip (Innsol Health Corp.) is primarily composed of sucrose and glucose; however, the full ingredient list includes pullulan, mannitol, menthol, hydroxyl propyl methyl cellulose, eucalyptol, polysorbate 80, glyceryl oleate, purified water.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Carbohydrate Mouth Rinse
Description: Participants are provided with a carbohydrate mouth rinse for every 12.5% of the time trial that is completed (calculated based on the distance covered).~The sucrose solution will consist of 64g of sucrose dissolved in 1000 mL of water, with a bolus of 25 mL being used for each mouth rinse. Each mouth rinse solution will have 2mL of red food dye FD\&C Red No. 40 to ensure the same sensory response through appearance.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Water Mouth Rinse
Description: Participants are provided with a water mouth rinse for every 12.5% of the time trial that is completed (calculated based on the distance covered).~The water solution will consist of 1000 mL of water, with a bolus of 25 mL being used for each mouth rinse. Each mouth rinse solution will have 2mL of red food dye FD\&C Red No. 40 to ensure the same sensory response through appearance.
Study: NCT04784663

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Messaging
Description: Four brief video messages, each approximately 1.5 minutes in length, focused on facilitating treatment seeking by addressing barriers and improving attitudes. Intervention delivered to participant by study mobile app downloaded to participants' own smartphone.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Wait list control
Description: one push notification each week thanking individuals for participation, informing them that they will receive messages in the near future or reminding them of the length of the study.
Study: NCT06391450

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 10 MG
Description: Oral

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral
Study: NCT06408168

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fulvestrant
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Repotrectinib
Description: Given by IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Repotrectinib
Description: Given by IV
Study: NCT06028477

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Stanford Glove
Description: The non-invasive neuromodulation hardware system comprises two wireless controllers/battery packs which are fastened to the top of each hand via an adjustable elastic strap. Each controller is equipped with four vibrotactile fingertip stimulators, also known as tappers. There is a total of eight tappers (for index, middle, ring and pinkie of each hand) per system.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Stanford Glove
Description: The non-invasive neuromodulation hardware system comprises two wireless controllers/battery packs which are fastened to the top of each hand via an adjustable elastic strap. Each controller is equipped with four vibrotactile fingertip stimulators, also known as tappers. There is a total of eight tappers (for index, middle, ring and pinkie of each hand) per system.