TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05411640

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise with Blood flow restriction
Description: Experimental group will be given aerobic exercises with blood flow restriction training. For first four weeks, aerobic exercise will be performed for 25 min with 60-65 % of the maximum heart rate reserve (MHRR). During second four weeks, time of exercise will be 30 min with intensity 60-65% of the MHRR, and for third four weeks, time will be increased to 35 min and intensity will be raised up to 70-75% of the MHRR. . Arterial occlusion of 60% will be achieved by Blood Flow Restriction apparatus. Total intervention protocol for this group will be given for 12 weeks of duration 4 sessions per week with total 48 sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic exercise without Blood flow restriction
Description: Active Comparator group will be given aerobic exercises. For first four weeks, aerobic exercise will be performed for 25 min with 60-65 % of the maximum heart rate reserve (MHRR). During second four weeks, time of exercise will be 30 min with intensity 60-65% of the MHRR, and for third four weeks, time will be increased to 35 min and intensity will be raised up to 70-75% of the MHRR. Total intervention protocol for this group will be given for 12 weeks of duration 4 sessions per week with total 48 sessions.

Intervention type: OTHER
Group type: OTHER
Intervention: Patient Education and dietary modification
Description: Participants will individually instruct to reduce total energy intake and increase physical activity, aiming at a 5% reduction in body weight. The participants will be given pamphlets providing general information on pre diabetes and dietary modifications. Total intervention protocol for the group will be given for 12 weeks of duration 4 sessions per week with total 48 sessions.
Study: NCT06182813

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Beta auditory beats (Group A)
Description: Beta auditory beats for 25 min and then perform alternate wall toss test.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: white noise (Group B)
Description: Involves participants receiving White noise for 25 min and then perform alternate wall toss test.
Study: NCT04772664

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Multispecies-Probiotic
Description: Participants in intervention group receive 2x3g of a multistrain probiotic containing Bifidobacterium bifidum W23, Bifidobacterium lactis W51, Bifidobacterium lactis W52, Lactobacillus acidophilus W22, Lactobacillus casei W56, Lactobacillus paracasei W20, Lactobacillus plantarum W62, Lactobacillus salivarius W24, Lactococcus lactis W19.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Multispecies-Probiotic
Description: Participants in intervention group receive 2x3g of a multistrain probiotic containing Bifidobacterium bifidum W23, Bifidobacterium lactis W51, Bifidobacterium lactis W52, Lactobacillus acidophilus W22, Lactobacillus casei W56, Lactobacillus paracasei W20, Lactobacillus plantarum W62, Lactobacillus salivarius W24, Lactococcus lactis W19.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Supplement
Description: Participants in the placebo group receive 2x3 gram of a placebo supplement not containing probiotic strains.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Supplement
Description: Participants in the placebo group receive 2x3 gram of a placebo supplement not containing probiotic strains.
Study: NCT06249919

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NS101
Description: NS101 is anti FAM19A5 antibody expected to play as a synapse organizer and reversing synapse dysfunction in various neurological diseases

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (i.e. fake drug without active pharmaceutical ingredient) of NS101

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo (i.e. fake drug without active pharmaceutical ingredient) of NS101

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo (i.e. fake drug without active pharmaceutical ingredient) of NS101
Study: NCT05442697

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PEMF treatment
Description: Patient will receive a PEMF treatment. The involved leg will be exposed to PEMF for 30 minutes per session, and the treatment regime will run three times a week for eight weeks, summing up 24 sessions of PEMF exposure in total.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo treatment
Description: Patient will receive a placebo treatment. The involved leg will be exposed to placebo treatment for 30 minutes per session, and the treatment regime will run three times a week for eight weeks, summing up 24 sessions of placebo exposure in total.
Study: NCT04986631

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topiramate Tablets
Description: Topiramate intervention
Study: NCT06214117

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam
Description: Anesthesia induction:intravenous Fentanyl 2-3 μg/kg, remimazolam 0.3-0.5 mg/kg and Rocuronium 0.6mg/kg; Maintenance of anesthesia:Remimazolam will infuse initially at a rate of 2 mg/kg/h (1-3 mg/kg/h), and remifentanil will administer at an initial infusion rate of 0.25 μg/kg/min (0.1-0.5 μg/kg/min).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sevoflurane
Description: Anesthesia induction: Anesthesia will induce with 8% sevoflurane in 100% oxygen at flow rate of 6 L/min, and then intravenous fentanyl (2-3 μg/kg) and rocuronium (0.6 mg/kg); Maintenance of anaesthesia: Anesthesia depth will maintain at 1-1.5 minimum alveolar concentration (MAC), and remifentanil was infuse at an initial rate of 0.25 μg/kg/min (0.1-0.5 μg/kg/min).
Study: NCT06013878

Intervention type: OTHER
Intervention: Transfer Training with clinician
Description: Participants will undergo transfer training with a clinician who is an expert on assisted transfer techniques if they are found to have skill deficits during the study. After training, a transfer assessment will be conducted to examine if the transfer skills of the caregiver have improved

Intervention type: OTHER
Intervention: Transfer Training with clinician
Description: Participants will undergo transfer training with a clinician who is an expert on assisted transfer techniques if they are found to have skill deficits during the study. After training, a transfer assessment will be conducted to examine if the transfer skills of the caregiver have improved
Study: NCT05023512

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communication about the COVID-19 vaccination from the Massachusetts Department of Public Health
Description: Participants will be randomized to receive one of two different versions of messages from the Massachusetts Department of Public Health. The message that participants in each experimental group receive will vary slightly and systematically. Specific content and wording of these messages were developed to address and mitigate concerns about the Covid-19 vaccination.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communication about the COVID-19 vaccination from the Massachusetts Department of Public Health
Description: Participants will be randomized to receive one of two different versions of messages from the Massachusetts Department of Public Health. The message that participants in each experimental group receive will vary slightly and systematically. Specific content and wording of these messages were developed to address and mitigate concerns about the Covid-19 vaccination.
Study: NCT05247749

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CONVIVO Confocal Endomicroscopy System
Description: Confocal Laser Endomicroscopy (CEM) system intended for viewing intra-operative blood flow in the cerebral vascular area. Manufacturer - Zeiss
Study: NCT04891458

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Patients received lighter sedation with propofol after spinal anesthesia.
Description: MOAA/S 0-2.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Patients received heavier sedation with propofol after spinal anesthesia
Description: MOAA/S 3-5.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Patients received lighter sedation with dexmedetomidine after spinal anesthesia
Description: MOAA/S 0-2.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Patients received heavier sedation with dexmedetomidine after spinal anesthesia.
Description: MOAA/S 3-5.
Study: NCT05569837

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Regular meal pattern
Description: 6 meals every day

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Irregular meal pattern
Description: It consists of consuming a different number of meals every day (between 3 and 9).
Study: NCT06554470

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Systemic Methotrexate
Description: Patients will receive systemic methotrexate (intramuscular; 50 mg/m2 body weight).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Local Methotrexate
Description: Patients will receive local methotrexate (25 mg methotrexate as a fixed dose).
Study: NCT06553196

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MATAspire Web-app
Description: Substance misuse prevention education and adaptive coping skills
Study: NCT05843136

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: physiotherapy treatment
Description: this is an interventional study of the use of 3 physiotherapy treatment techniques in order to evaluate the effectiveness of interferential current in relieving chronic low back pain

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: physiotherapy treatment
Description: this is an interventional study of the use of 3 physiotherapy treatment techniques in order to evaluate the effectiveness of interferential current in relieving chronic low back pain
Study: NCT06060535

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Suicide Attempt Risk Model Care Pathway
Description: The suicide attempt risk model uses documented histories of medical and psychiatric diagnoses, medications, and health service utilization to predict risk of a suicide attempt in the 90 days following an outpatient visit in behavioral health clinics.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Suicide Attempt Risk Model Care Pathway
Description: The suicide attempt risk model uses documented histories of medical and psychiatric diagnoses, medications, and health service utilization to predict risk of a suicide attempt in the 90 days following an outpatient visit in behavioral health clinics.
Study: NCT05843136

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physiotherapy treatment
Description: this is an interventional study of the use of 3 physiotherapy treatment techniques in order to evaluate the effectiveness of interferential current in relieving chronic low back pain
Study: NCT06247514

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The BEET Diabetes Program
Description: The BEET Diabetes program is an adapted CBT program specifically designed to treat disordered eating and improve diabetes self-management. Participants receive support from BHPs to guide them through the program, maintain motivation, and facilitate appropriate goal setting.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy Guided Self-Help
Description: 6-session cognitive behavioral therapy delivered through the self-help book Overcoming Binge Eating Self-help by Christopher G. Fairburn.~The manual focuses on reducing binge-eating episodes. Guided support sessions can be provided by personnel with no background training or knowledge of CBT or disordered eating behaviors, as the book acts as the expert.
Study: NCT05633914

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tucidinostat
Description: 20mg, po., biw, q3w

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nab-paclitaxel
Description: 125mg/m2, d1, iv.drip, q7d
Study: NCT06715748

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ketone Monoester (KE)
Description: Participants will perform a randomized, double-blind ZWIFT event, once with ketone ester intake and once with placebo, separated by an interval of 1-4 weeks. Ketones and placebo will be orally administered according to a fixed schedule.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will perform a randomized, double-blind ZWIFT event, once with ketone ester intake and once with placebo, separated by an interval of 1-3 weeks. Ketones and placebo will be orally administered according to a fixed schedule.
Study: NCT05499000

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional freedom technique
Description: Emotional freedom technique will be applied online with the researcher in 2 sessions, 3 days apart.~KBF, SUE, PMSS tests will be applied before the intervention, SUE will be applied before and after each session, At the end of the 2nd session, post-test data will be taken with SUE, PMSS.
Study: NCT06719336

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: High-dose Hyperfractionated Simultaneous Integrated Boost Radiotherapy
Description: Twice-daily thoracic radiotherapy at a dose of 54 Gy in 30 fractions with IMRT and VMAT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: atezolizumab or durvalumab
Description: atezolizumab 1200 mg Q3W or durvalumab 1500 mg Q4W

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: atezolizumab or durvalumab
Description: atezolizumab 1200 mg Q3W or durvalumab 1500 mg Q4W
Study: NCT06062134

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pericapsular nerve group block
Description: Ultrasound-guided injection of local anesthetic mixed with contrast agent underneath the iliopsoas muscle, lateral to the iliopsoas tendon.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18 mL ropivacaine 0.5% + 2 mL radiopaque contrast
Description: 20 mL of injectate: 18 mL ropivacaine 0.5% + 2 mL radiopaque contrast (Iomeron 300: 61.24% w/v of iomeprol equivalent to 30% iodine or 300 mg iodine/mL)
Study: NCT06750094

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Amivantamab
Description: Amivantamab will be administered.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Cetuximab
Description: Cetuximab will be administered.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Bevacizumab
Description: Bevacizumab will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-fluorouracil
Description: 5-fluorouracil will be administered as chemotherapy regimen.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5-fluorouracil
Description: 5-fluorouracil will be administered as chemotherapy regimen.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin calcium/Levoleucovorin
Description: Leucovorin calcium/Levoleucovorin will be administered as chemotherapy regimen.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leucovorin calcium/Levoleucovorin
Description: Leucovorin calcium/Levoleucovorin will be administered as chemotherapy regimen.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Irinotecan will be administered as chemotherapy regimen.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Irinotecan
Description: Irinotecan will be administered as chemotherapy regimen.
Study: NCT04164277

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiver Component.
Description: Facebook-based program including four new habit-formation tasks/week. Three face-to-face or virtual caregiver meetings: Meeting 1: Study orientation and healthy cooking education will be offered, and each family will receive a small bag of groceries to facilitate preparation of a recipe at home. Each caregiver will also receive an intervention cookbook containing affordable slow-cooking recipes, quick-fix recipes, and healthy snack ideas. Meeting 2: Study interveners will demonstrate how to spend less and shop healthy and how to read nutrition fact labels to promote healthy purchasing behaviors. Meeting 3: Study interveners will present healthy eating and PA community resources (e.g., farmer's markets, community gardens, nearly parks or other free or affordable PA facilities) and provide caregivers a resource booklet.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiver-Preschooler Learning.
Description: Preschoolers, using stickers, will create two letters each week regarding a food or activity presented in the center-based program that they liked or want to try at home. Letters will be sent by the PM privately to each caregiver via Facebook messenger on two weekdays. Caregivers will be asked to answer two Facebook multiple-choice questions related to the letters each week by Sunday midnight (e.g., what foods listed in the their child's letter did the participant provide? and what activities listed in the their child's letter did the participant's family try?). Caregiver responses to the questions will be summed to indicate caregiver responses to child requests. Each preschooler's letters will be kept in his/her intervention binder with other intervention materials to present to his/her caregiver at Meeting 3. Weekly preschooler activities, with pictures or videos, will be shared with caregivers via the Facebook private group every week.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Center-based Preschooler Component.
Description: Built on previous research, preschoolers will receive weekly, age-appropriate, participatory learning co-delivered by teachers and MSU student educators. Session duration will be 20 minutes because children's normal attention span is 3-5 minutes per year of age, and 20 min/session is recommended for preschoolers. The already developed Eat \& Walk My ABCs curriculum will be implemented. The curriculum includes four components: healthy eating learning, taste-testing activities, movement skill training, and fun physical activity.
Study: NCT05308121

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of Achilles tendon
Description: The biomechanical and viscoelastic properties of the Achilles tendon will be measured in the side lying position. Measurements will be taken from two different points with the ankle in the neutral position.

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of Achilles tendon
Description: The biomechanical and viscoelastic properties of the Achilles tendon will be measured in the side lying position. Measurements will be taken from two different points with the ankle in the neutral position.

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of Achilles tendon
Description: The biomechanical and viscoelastic properties of the Achilles tendon will be measured in the side lying position. Measurements will be taken from two different points with the ankle in the neutral position.
Study: NCT05590273

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CALM Therapy
Description: The CALM intervention includes 3 to 6 individual therapy Zoom teletherapy sessions, each approximately 50-60 minutes in length biweekly, delivered over 3 months. Participants (caregivers) will be asked to complete self-report surveys of behavioral and psychological variables surveys at the following timepoints:~Within one week before initiating the CALM intervention therapy (baseline) and immediately after the program (post-intervention)~In addition, after each intervention session, participants will complete a brief post-session survey to assess acceptability of CALM session components.~Lastly, participants will complete an exit interview immediately following the end of the intervention.
Study: NCT05988307

Intervention type: DEVICE
Group type: OTHER
Intervention: Percussion massage gun
Description: Percussion massage gun on hamstrings flexibility in patients with knee Osteoarthritis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percussion massage gun
Description: Percussion massage gun on hamstrings flexibility in patients with knee Osteoarthritis.
Study: NCT06555627

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High Protein Breakfast
Description: For 5 days children will receive a high protein breakfast comprised of baked items (i.e. waffles with syrup) and Greek yogurt. The high protein meal will aim for 40% protein, 40% carbohydrates, and 20% fat. Meals will be served with a cup of water.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: High Protein Breakfast
Description: For 5 days children will receive a high protein breakfast comprised of baked items (i.e. waffles with syrup) and Greek yogurt. The high protein meal will aim for 40% protein, 40% carbohydrates, and 20% fat. Meals will be served with a cup of water.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Morning Exercise
Description: Exercise Intervention. For 5 days, a 30-min physical activity bout including a 5-minute warm up and cool down will be provided to participants in this group. The aim is for students to achieve an average heart rate above 150 for the session, not including warm up or cool down. To monitor intensity, the participant will wear heart rate monitors around their chest and waist-worn accelerometers.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Morning Exercise
Description: Exercise Intervention. For 5 days, a 30-min physical activity bout including a 5-minute warm up and cool down will be provided to participants in this group. The aim is for students to achieve an average heart rate above 150 for the session, not including warm up or cool down. To monitor intensity, the participant will wear heart rate monitors around their chest and waist-worn accelerometers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: High Carb Breakfast
Description: For 5 days children will receive a high carb breakfast that will be comprised of 15% protein, 65% carbohydrates and 20% fat. Total energy content, fat, sugar, fiber, energy density, are similar between the breakfast meals.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: High Carb Breakfast
Description: For 5 days children will receive a high carb breakfast that will be comprised of 15% protein, 65% carbohydrates and 20% fat. Total energy content, fat, sugar, fiber, energy density, are similar between the breakfast meals.
Study: NCT05308121

Intervention type: OTHER
Intervention: Evaluation of foot characteristics
Description: The mobility of foot, morphological changes of foot and foot posture will be evaluated

Intervention type: OTHER
Intervention: Evaluation of foot characteristics
Description: The mobility of foot, morphological changes of foot and foot posture will be evaluated

Intervention type: OTHER
Intervention: Evaluation of foot characteristics
Description: The mobility of foot, morphological changes of foot and foot posture will be evaluated