TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06392295

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Para Aortic Radiation Therapy: Photon Therapy
Description: Participants will undergo five weeks of PA-RT daily, for up to 30 minutes per day for 25 days, Monday through Friday, consisting of a total dose of 50 grays (Gys) delivered in 25 fractions to the Clinical Tumor Volume (CTV).

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Para Aortic Radiation Therapy: Proton Therapy
Description: Participants will undergo five weeks of PA-RT daily, for up to 30 minutes per day for 25 days, Monday through Friday, consisting of a total dose of 60 to 65 Gys delivered in 25 fractions to the Gross Tumor Volume (GTVn).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Androgen Deprivation Therapy
Description: Androgen deprivation therapy will be administered as per standard of care.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Androgen Receptor Signaling Inhibitor
Description: Androgen receptor signaling inhibitor (ARSI) will be administered as per standard of care.
Study: NCT05494515

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: the early swallowing rehabilitation program
Description: the early swallowing rehabilitation program based on the HRIM evaluation
Study: NCT06428981

Intervention type: OTHER
Group type: OTHER
Intervention: degenerative cervical diseases
Description: Including herniation of the intervertebral disc, ossification of the posterior longitudinal ligament, and spinal stenosis, resulting in cervical radiculopathy, or degenerative cervical myelopathy, and were scheduled to undergo anterior discectomy with fusion surgery.
Study: NCT05261035

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: stretching exercises
Description: For the stretching exercises group; the researchers explained to the women how to perform the stretching exercises through different visual materials like videos \& pictures, provided a demonstration of each step, and emphasized that they could perform this exercise at any comfortable position, standing, sitting, or dorsal.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: thermotherapy
Description: women were instructed to warm the water to 43-47 C° using a water thermometer or test it with the inner aspect of their wrists. They are also advised to avoid using too hot or too cold water. Then immerse their legs for 20 minutes in the warm water at a h
Study: NCT06100653

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BCG for therapeutic use
Description: The 10 patients were infused with BCG 120mg dissolved in 40 \~ 50 mL normal saline once a week for 6 times, then once every 2 weeks for 3 times, and then once a month (30 days) for 10 times, with a total of 19 times.
Study: NCT05891184

Intervention type: DEVICE
Intervention: color doppler ultrasound, transient elastography, upper endoscopy
Description: Abdominal US: for detecting the portal hypertension, splenomegaly and portosystemic abdominal collaterals .~Doppler US: detecting the diameter and mean blood flow velocity, blood flow volume, perfusion pressure gradient, congestion index, resistive index, pulsatility index of hepatic artery and platelet count-to-spleen diameter ratio will be performed using logic 10 with a 3.5-MHz duplex convex transducer, in supine position after overnight fasting, with holding their breath in maximal expiration in order to minimize the effect of respiration, body position and postprandial changes on the portal flow Endoscopy : Using Sarin classification ( The presence of esophageal varices, their number, exact location, shape, size and cherry-red spots ) Fibroscan: using the standard-probe, and on a fasting (4 h) patient lying flat on his/her back, with the right arm tucked behind the head to facilitate access to the right upper quadrant.

Intervention type: DEVICE
Intervention: color doppler ultrasound, transient elastography, upper endoscopy
Description: Abdominal US: for detecting the portal hypertension, splenomegaly and portosystemic abdominal collaterals .~Doppler US: detecting the diameter and mean blood flow velocity, blood flow volume, perfusion pressure gradient, congestion index, resistive index, pulsatility index of hepatic artery and platelet count-to-spleen diameter ratio will be performed using logic 10 with a 3.5-MHz duplex convex transducer, in supine position after overnight fasting, with holding their breath in maximal expiration in order to minimize the effect of respiration, body position and postprandial changes on the portal flow Endoscopy : Using Sarin classification ( The presence of esophageal varices, their number, exact location, shape, size and cherry-red spots ) Fibroscan: using the standard-probe, and on a fasting (4 h) patient lying flat on his/her back, with the right arm tucked behind the head to facilitate access to the right upper quadrant.

Intervention type: DEVICE
Intervention: color doppler ultrasound, transient elastography, upper endoscopy
Description: Abdominal US: for detecting the portal hypertension, splenomegaly and portosystemic abdominal collaterals .~Doppler US: detecting the diameter and mean blood flow velocity, blood flow volume, perfusion pressure gradient, congestion index, resistive index, pulsatility index of hepatic artery and platelet count-to-spleen diameter ratio will be performed using logic 10 with a 3.5-MHz duplex convex transducer, in supine position after overnight fasting, with holding their breath in maximal expiration in order to minimize the effect of respiration, body position and postprandial changes on the portal flow Endoscopy : Using Sarin classification ( The presence of esophageal varices, their number, exact location, shape, size and cherry-red spots ) Fibroscan: using the standard-probe, and on a fasting (4 h) patient lying flat on his/her back, with the right arm tucked behind the head to facilitate access to the right upper quadrant.
Study: NCT05656625

Intervention type: OTHER
Intervention: descriptive
Description: The block performed (distal peripheral nerve block and/or brachial nerve block) and the volume applied, block performance time, first analgesia times, surgery times, surgery types, discharge times, presence of additional complaints will be recorded. The data obtained by grouping the patients according to the type of anesthesia applied (brachial plexus block and distal nerve blocks) will be subjected to statistical analysis.

Intervention type: OTHER
Intervention: descriptive
Description: The block performed (distal peripheral nerve block and/or brachial nerve block) and the volume applied, block performance time, first analgesia times, surgery times, surgery types, discharge times, presence of additional complaints will be recorded. The data obtained by grouping the patients according to the type of anesthesia applied (brachial plexus block and distal nerve blocks) will be subjected to statistical analysis.
Study: NCT05458050

Intervention type: DEVICE
Group type: OTHER
Intervention: PU sensor
Description: Device to assess microcirculation in sacrum area to find subjects at risk for pressure ulcer
Study: NCT05563675

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Long acting muscarinic antagonists (LAMAs) in the evening
Description: LAMAs administered at bedtime (8pm - 2am)
Study: NCT05035576

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: OPN-019
Description: 400 mg OPN-019, 2 sprays per nostril (one dose)
Study: NCT06461182

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ga-68-CXCR4
Description: Ga-68-CXCR4 for PET/CT procedure in Indolent B-cell Lymphoma
Study: NCT06441045

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Double Dose of Third-generation EGFR-TKI
Description: Double Dose of Third-generation EGFR-TKI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Double Dose of Third-generation EGFR-TKI
Description: Double Dose of Third-generation EGFR-TKI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intrathecal Pemetrexed
Description: Intrathecal Pemetrexed
Study: NCT05467215

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pure oxygen (99%) from Praxair, Edmonton, DIN# 02014408
Description: Participants will receive oxygen (99%) or room air (placebo) delivered through a face mask at a flow rate of 10 litres/min for 2 minutes. The participants will be exposed twice to both conditions over 4 experiments at a minimum of 2 week intervals between each testing session.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pure oxygen (99%) from Praxair, Edmonton, DIN# 02014408
Description: Participants will receive oxygen (99%) or room air (placebo) delivered through a face mask at a flow rate of 10 litres/min for 2 minutes. The participants will be exposed twice to both conditions over 4 experiments at a minimum of 2 week intervals between each testing session.
Study: NCT05148039

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dietician advice
Description: Personalised dietetic advice

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dietician advice
Description: Personalised dietetic advice
Study: NCT05338346

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATG-018
Description: Dose Escalation Phase:~For both dose escalation groups, subjects will receive a single dose of ATG-018 monotherapy on Cycle 1 Day 1 (C1D1) for single dose PK samples' collection. From the morning dose on Cycle 1 Day 2, twice daily dosing (except Dose Level 1: 5 mg QD) will be initiated. Subject(s) will receive intermittent dosing in a 3 days on/4 days off schedule in 21-day cycles until disease progression or unacceptable toxicity.~Dose Expansion Phase :~Dose Expansion Phase will begin at the defined MTD/RP2D for solid tumors and hematological malignancies groups, to further evaluate the safety, tolerability, and PDx profile of ATG-018. Subjects with solid tumors and hematological malignancies will be enrolled.
Study: NCT05712057

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: high frequency rTMS over the right dlPFC

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: high frequency rTMS over the right dlPFC

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: electrical scalp stimulation
Description: electrical scalp stimulation over the right dlPFC

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Restructuring
Description: Cognitive restructuring is a cognitive behavioral intervention through which participants learn how to think differently about stressful events in order to feel less emotional arousal.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Restructuring
Description: Cognitive restructuring is a cognitive behavioral intervention through which participants learn how to think differently about stressful events in order to feel less emotional arousal.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Emotional Awareness Training
Description: Emotional awareness training is a behavioral intervention through which participants learn how to identify and evaluate their emotions and the components that make up each emotion.
Study: NCT06249724

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active stimulation using low-frequency ultrasonic transducer
Description: The ultrasonic transducer delivers focused low-intensity ultrasound stimulation

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation using low-frequency ultrasonic transducer
Description: The ultrasonic transducer delivers focused zero-intensity ultrasound stimulation
Study: NCT00631501

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxycycline
Study: NCT05429957

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Energy Technique
Description: Muscle energy technique (Post Isometric relaxation) three times per week for 8 weeks.~* MET of the Iliopsoas~* MET of Piriformis muscle~* MET of Quadratus Lumborum muscle~* MET of Erector Spinae muscle

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercises
Description: Aerobic exercise (treadmill walking) three times per week for 8 weeks~* Warm-up phase: in which each patient alternately steps their legs forward, backward, and sideways in each direction for 5 min~* Active phase: Treadmill speed was 3km/hour for 5 weeks and progress to 4km/hour after 5 weeks for 20 min.~* Cool down phase: During a cool down period take a deep breath with both arms overhead and exhale while bringing the arms down, shaking out the legs and arms for 5 min.
Study: NCT05109676

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire
Description: A questionnaire will be offered to patients and identify the schedules of administration of progesterone, the day and time of blood samples taken as part of the care, the potential adverse events associated with this administration.
Study: NCT05355779

Intervention type: OTHER
Intervention: Not Application as this is a qualitative study
Description: Not Application as this is a qualitative study
Study: NCT05482126

Intervention type: DIAGNOSTIC_TEST
Intervention: Intraoperative Behavioral Testing
Description: During DBS surgery, tasks will be administered via a tablet PC or mounted monitor, and the subject may hold a response box, joystick, or dynamometer to record responses. During task periods, sensory stimuli will be delivered to the participant, who may be asked to perform a motor behavior in response. Stimuli will consist of audiovisual cues presented on a computer screen, vibration applied to specific parts of the body via a tactor, mild electrical pulses delivered through the skin of specific parts of the body via the attached EMG electrodes, and/or a movement of the arm or joint. Motor responses will consist of simple movements such as finger-tapping or hand-opening, or use of a joystick or dynamometer to move a computer cursor on the screen. Participants may be asked to respond only to a particular sensory stimulus and ignore others, in order to modulate the relevance of each stimulus to the task.

Intervention type: DIAGNOSTIC_TEST
Intervention: Behavioral Testing
Description: In the lab, tasks will be administered via a tablet PC or mounted monitor, and the subject may hold a response box, joystick, or dynamometer to record responses. During task periods, sensory stimuli will be delivered to the participant, who may be asked to perform a motor behavior in response. Stimuli will consist of audiovisual cues presented on a computer screen, vibration applied to specific parts of the body via a tactor, mild electrical pulses delivered through the skin of specific parts of the body via the attached EMG electrodes, and/or a movement of the arm or joint. Motor responses will consist of simple movements such as finger-tapping or hand-opening, or use of a joystick or dynamometer to move a computer cursor on the screen. Participants may be asked to respond only to a particular sensory stimulus and ignore others, in order to modulate the relevance of each stimulus to the task.

Intervention type: DIAGNOSTIC_TEST
Intervention: Behavioral Testing
Description: In the lab, tasks will be administered via a tablet PC or mounted monitor, and the subject may hold a response box, joystick, or dynamometer to record responses. During task periods, sensory stimuli will be delivered to the participant, who may be asked to perform a motor behavior in response. Stimuli will consist of audiovisual cues presented on a computer screen, vibration applied to specific parts of the body via a tactor, mild electrical pulses delivered through the skin of specific parts of the body via the attached EMG electrodes, and/or a movement of the arm or joint. Motor responses will consist of simple movements such as finger-tapping or hand-opening, or use of a joystick or dynamometer to move a computer cursor on the screen. Participants may be asked to respond only to a particular sensory stimulus and ignore others, in order to modulate the relevance of each stimulus to the task.
Study: NCT06328998

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine rehabilitation treatment
Description: Routine rehabilitation treatment Includes oral rehabilitation, rehabilitation training for temporomandibular disorders, orthodontic treatment, and other physical therapy methods.which can alleviate symptoms by adjusting the bite, relaxing muscles, and increasing the range of motion of the temporomandibular joint.~Besides, it also Includes temporomandibular joint exercise training, relaxation training for facial muscles, and functional chewing training aimed at improving temporomandibular joint function and muscle balance.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine rehabilitation treatment
Description: Routine rehabilitation treatment Includes oral rehabilitation, rehabilitation training for temporomandibular disorders, orthodontic treatment, and other physical therapy methods.which can alleviate symptoms by adjusting the bite, relaxing muscles, and increasing the range of motion of the temporomandibular joint.~Besides, it also Includes temporomandibular joint exercise training, relaxation training for facial muscles, and functional chewing training aimed at improving temporomandibular joint function and muscle balance.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intra-articular Injection
Description: The patient is positioned to maximize mouth opening, and a needle is inserted approximately 10-12 mm in front of the tragus after touching the ankle prominence. An 8# injection needle is chosen and inserted upward and slightly forward into the joint cavity. A total of 2 mL of lidocaine hydrochloride injection solution is injected, repeated once every 5 days for a total of 15 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine Hydrochloride
Description: The patient is positioned to maximize mouth opening, and a needle is inserted approximately 10-12 mm in front of the tragus after touching the ankle prominence. An 8# injection needle is chosen and inserted upward and slightly forward into the joint cavity. A total of 2 mL of lidocaine hydrochloride injection solution is injected, repeated once every 5 days for a total of 15 days.
Study: NCT05371652

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimegepant 75mg Orally Disintegrating Tablets (ODT)
Description: One rimegepant (BHV3000) 75mg orally disintegrating tablet (up to 1 tablet per day) at the time of their migraine attack
Study: NCT05950815

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD73 Antigen
Description: subjects will be administered with PM1015 via intravenously (IV) Q2W pemetrexed until progression or accepted other treatment.
Study: NCT04876755

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBM-02
Description: MBM-02 is an HIF-1 and HIF-2 inhibitor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBM-02
Description: MBM-02 is an HIF-1 and HIF-2 inhibitor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBM-02
Description: MBM-02 is an HIF-1 and HIF-2 inhibitor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBM-02
Description: MBM-02 is an HIF-1 and HIF-2 inhibitor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBM-02
Description: MBM-02 is an HIF-1 and HIF-2 inhibitor.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBM-02
Description: MBM-02 is an HIF-1 and HIF-2 inhibitor.
Study: NCT05643612

Intervention type: DIAGNOSTIC_TEST
Intervention: Deep learning algorithm
Description: A sequential two-stage 3D spleen injury detection framework to identify splenic injury in the CT scans

Intervention type: DIAGNOSTIC_TEST
Intervention: Deep learning algorithm
Description: A sequential two-stage 3D spleen injury detection framework to identify splenic injury in the CT scans
Study: NCT06098898

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NK510
Description: NK510 will be administered through intravenous infusion.3 infusions on Day 0，Day 2 and day 3 for a cycle，for a total of two cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NK510
Description: NK510 will be administered through intravenous infusion.3 infusions on Day 0，Day 2 and day 3 for a cycle，for a total of two cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NK510
Description: NK510 will be administered through intravenous infusion.3 infusions on Day 0，Day 2 and day 3 for a cycle，for a total of two cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab，atezolizumab or Trastuzumab
Description: Administer according to the instructions.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab，atezolizumab or Trastuzumab
Description: Administer according to the instructions.
Study: NCT05218590

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Video rigid stylet
Description: Nasal intubation was performed using the video rigid stylet.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Video rigid stylet
Description: Nasal intubation was performed using the video rigid stylet.
Study: NCT05868551

Intervention type: PROCEDURE
Intervention: nodulectomy
Description: incision in an onchocerciasis nodule to extract adult worms
Study: NCT06090526

Intervention type: DIAGNOSTIC_TEST
Intervention: pancreatic stone protein PSP measurement
Description: Blood samples will be collected for biomarker (PCT, CRP, and PSP) measurements in admission and 24 hours, 72 hours from admission and patients will be followed until death or discharge from the ICU or for 30 days, whichever occurred.

Intervention type: DIAGNOSTIC_TEST
Intervention: pancreatic stone protein PSP measurement
Description: Blood samples will be collected for biomarker (PCT, CRP, and PSP) measurements in admission and 24 hours, 72 hours from admission and patients will be followed until death or discharge from the ICU or for 30 days, whichever occurred.
Study: NCT03617250

Intervention type: OTHER
Intervention: Disease Activity Score-28
Description: Assessment of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio and their association with Disease Activity Score-28

Intervention type: OTHER
Intervention: Disease Activity Score-28
Description: Assessment of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio and their association with Disease Activity Score-28
Study: NCT05757336

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination of Gemcitabine, Nab-paclitaxel, Sintilimab and Bevacizumab
Description: Combination of Gemcitabine, Nab-paclitaxel, Sintilimab and Bevacizumab
Study: NCT06272786

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional physiotherapy program.
Description: It will be applied to a rehabilitation program including joint range of motion exercises and physical therapy modalities by a physiotherapist at the Physical Therapy Hospital.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: conventional physiotherapy program.
Description: It will be applied to a rehabilitation program including joint range of motion exercises and physical therapy modalities by a physiotherapist at the Physical Therapy Hospital.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suprascapular nerve block
Description: Bupivacaine hydrochloride will be used in this injection. 5 ml of bupivacaine hydrochloride 5% and 5 ml of saline will be drawn into a 10 ml syringe and ejection will be performed from the superior of the suprascapular noch under USG guidance.