TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05145036

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tai-Chi
Description: Tai Chi exercise could improve muscle performance, balance and have the benefit for fall down prevention in the elders and patients with frailty.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Comprehensive training
Description: There are 3 exercises. Each session consisted of 10 minutes of warm-up, 40 minutes of Tai Chi, and 10 minutes of cool down.
Study: NCT04611217

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary fiber: 10-25g
Description: 10-25 g/day of fiber

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary fiber: 5g
Description: 5 g/day of fiber
Study: NCT05621473

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PICC
Description: Tunnel PICC puncture technology is a perfect combination of ultrasound-guided puncture, ECG lead technology, PICC and subcutaneous tunnel. The valve conduction PICC is equipped with an integrated ECG lead Doppler ultrasound machine. Before the catheter is placed, in the yellow area, in the ultrasound mode, evaluate the blood vessel condition, measure the blood flow velocity, and correctly select the puncture site. When the catheter is pushed close to the superior vena cava, the electrocardiograph mode is switched to complete the precise positioning of the catheter according to the principle of ECG positioning technology. A subcutaneous tunnel was prepared in the green area, and the PICC at the puncture site in the yellow area was introduced to the green area and carefully bandaged. Whole-process integrated operation, simple and efficient operation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PICC
Description: Tunnel PICC puncture technology is a perfect combination of ultrasound-guided puncture, ECG lead technology, PICC and subcutaneous tunnel. The valve conduction PICC is equipped with an integrated ECG lead Doppler ultrasound machine. Before the catheter is placed, in the yellow area, in the ultrasound mode, evaluate the blood vessel condition, measure the blood flow velocity, and correctly select the puncture site. When the catheter is pushed close to the superior vena cava, the electrocardiograph mode is switched to complete the precise positioning of the catheter according to the principle of ECG positioning technology. A subcutaneous tunnel was prepared in the green area, and the PICC at the puncture site in the yellow area was introduced to the green area and carefully bandaged. Whole-process integrated operation, simple and efficient operation.
Study: NCT06196359

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combined Femoral and Popliteal nerve block
Description: Patients who receive a combined femoral and popliteal nerve block during surgery, fill out a questionnaire and undergo a muscle strength test before surgery, undergo functional tests, a muscle strength test and are asked about pain intensity after surgery.
Study: NCT06009874

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin 10mg Tab
Description: patients will be treated with DAPA 10 mg once daily for three months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: patients will be treated with a placebo tab once daily for three months
Study: NCT05726136

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: acetated Ringers
Description: After insufflation of carbon dioxide during an abdominal laparoscopic procedure, the first fluid bolus is infused. Circulatory and volume effects are studied. If cardiac output increase a second bolus is infused and studied.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: albumin 5%
Description: After insufflation of carbon dioxide during an abdominal laparoscopic procedure, the first bolus of fluid is infused. Circulatory and volume effects are studied. If cardiac output increases a second bolus is infused and studied.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: albumin 20%
Description: After insufflation of carbon dioxide during an abdominal laparoscopic procedure, the first bolus of fluid is infused. Circulatory and volume effects are studied. If cardiac output increases a second bolus is infused and studied.
Study: NCT03953144

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IC-Green (ICG)
Description: ICG will be prepared as a sterile solution (2.5 mg/10mL) for injection. After vascular ligation, a 6 to 8mL bolus of ICG solution will be injected into the peripheral vein catheter, followed by a 10mL saline solution bolus. The Firefly camera will then be used for the NIF imaging. It is expected that the entire lung, except the segment which was previously isolated from blood supply, will fluoresce within 30-40 seconds, exhibiting a green hue. The surgeon will perform the pulmonary resection and the resected 'dark' lung segment will be immediately evaluated by a pathologist, depending on the pathologist findings the operation may be concluded or the patient will receive a pulmonary lobectomy.
Study: NCT05551897

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camizestrant
Description: Subjects will be administered a single oral dose of Camizestrant on Day 1 of treatment period 1 and treatment period 3.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Subjects will be administered Itraconazole twice a day on Day 1 and once daily on Day 2 and Day 3 of treatment period 2, and once daily on Day 1, 2 and 3 of treatment period 3.
Study: NCT04925934

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VIB7734
Description: VIB7734
Study: NCT06349629

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D printed WE43 magnesium alloy
Description: This 3D printed WE43 magnesium alloy has porous structure and suitable mechanical strength, can be stable in the bone support, and gradually degrade to promote bone healing.
Study: NCT04925934

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VIB7734
Description: VIB7734

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT04561492

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-PentixaFor
Description: Tomography by emission of positons (PET) with theradiopharmaceutic \[68Ga\]Ga-PentixaFor
Study: NCT06349629

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D printed WE43 magnesium alloy
Description: This 3D printed WE43 magnesium alloy has porous structure and suitable mechanical strength, can be stable in the bone support, and gradually degrade to promote bone healing.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D printed WE43 magnesium alloy
Description: This 3D printed WE43 magnesium alloy has porous structure and suitable mechanical strength, can be stable in the bone support, and gradually degrade to promote bone healing.
Study: NCT05946590

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Frenotomy
Description: Frenotomy in which clipping/incised of the lingual frenulum releases the tongue-tie performed by a health care professional
Study: NCT05316896

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internal Perturbation
Description: * Raising and lowering arms 90 degrees forward and sideways with eyes open and closed.~* In tandem stance with eyes open and closed, arms are raised and lowered 90 degrees forward and to the side.~* While standing on one leg with eyes open and closed, arms are raised and lowered 90 degrees forward and to the side.~* Step forward and backward with right and left foot alternately~* Take a step back and step back alternately with right and left foot~* Put the right foot on the step and take it back, then do the same with the left foot and ask the patient to do it quickly.~* First step on the step with the right foot and put the left foot next to it, then step down with the right foot and take the left foot with it, repeat the same with the left foot and ask the patient to do this. rapidly.~* Normal gait, sideways gait, tandem gait, backward gait, raising and lowering the arms forward and sideways 90 degrees, respectively, during back-to-back tandem gait.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eksternal Perturbation
Description: * Front, side, and rear loading and release, pushing and pulling while standing with eyes open and closed~* Front, side and rear loading and release, pushing and pulling while standing in tandem with eyes open and closed~* Loading and releasing from the front, sides and back, pushing and pulling while turning the head left and right while standing~* Front, side and rear loading and release, pushing and pulling while standing up and down with eyes open and closed~* Front, side, and rear loading and release, pushing and pulling while standing on one leg with eyes open and closed~* Holding the ball thrown by physiotherapist~* Kicking a ball thrown by physiotherapist~* Holding the ball thrown by the physiotherapist while standing in tandem, walking, walking sideways, walking in tandem, walking backwards.
Study: NCT04288245

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active Vagus Nerve Stimulation
Description: Stimulation of the vagus nerve that is paired with upper extremity rehabilitation. VNS stimulation as described in the current study consists of 0.5 s trains of 0.8 mA 100 µs biphasic pulses delivered at 30 Hz. Stimulation trains are delivered only during rehabilitation.
Study: NCT05184738

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Treatment, Oligomeric nutritional formula
Description: Intervention group will receive a oligomeric nutritional formula (Bi1 peptidic Adventia Pharma, Spain).
Study: NCT04288245

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Vagus Nerve Stimulation
Description: During Phase 1 of the study, the placebo group will receive a minimal amount of stimulation that fails to sufficiently activate the nerve, unknown to the participant and therapists. All participants will receive active stimulation during the Phase 2 open-label portion of the study.
Study: NCT05184738

Intervention type: OTHER
Group type: OTHER
Intervention: Control Treatment
Description: Standard nutritional formula (isocaloric and isoprotein compared to the experimental treatment).
Study: NCT05794282

Intervention type: PROCEDURE
Intervention: the robot assisted total hip arthroplasty
Description: the robot assisted total hip arthroplasty

Intervention type: PROCEDURE
Intervention: the conventional total hip arthroplasty
Description: the conventional total hip arthroplasty
Study: NCT05976386

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dupilumab (SAR231893)
Description: Injection solution Subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab (SAR231893)
Description: Injection solution Subcutaneous
Study: NCT06609343

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupropion Hydrochloride 150 MG
Description: Bupropion Hydrochloride Extended Release is administered orally three times a week during routine dialysis sessions for 8 consecutive weeks
Study: NCT05017480

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBP-201
Description: CBP-201 subcutaneous(SC) injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: subcutaneous(SC) injection
Study: NCT05217524

Intervention type: DEVICE
Intervention: Galaxy BIA watch
Description: Digital multifunction watch

Intervention type: DEVICE
Intervention: Galaxy BIA watch
Description: Digital multifunction watch
Study: NCT06118047

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Crisaborole Ointment
Description: Crisaborole ointment to be applied twice daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: Cetuximab
Study: NCT06487156

Intervention type: DRUG
Intervention: Nivolumab + ipilimumab
Description: As per product label
Study: NCT06532994

Intervention type: OTHER
Intervention: Early rehabilitation intervention
Description: Based on the indications for early rehabilitation intervention outlined in the Chinese Expert Consensus on Neurological Critical Care Rehabilitation, early rehabilitation interventions are categorized into three stages according to the patient's consciousness level (GCS score), degree of cooperation (S5Q score), and sedation status (RASS score)
Study: NCT05732207

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cerebellar transcranial direct current stimulation
Description: TDCS is a safe and non-invasive technique for modulating cortical excitability and behavior. TDCS, delivered via surface electrodes, induces an intracerebral current flow sufficient to achieve changes in cortical excitability. Anodal stimulation up-regulates cortical excitability, while cathodal stimulation decreases excitability.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cerebellar transcranial direct current stimulation
Description: TDCS is a safe and non-invasive technique for modulating cortical excitability and behavior. TDCS, delivered via surface electrodes, induces an intracerebral current flow sufficient to achieve changes in cortical excitability. Anodal stimulation up-regulates cortical excitability, while cathodal stimulation decreases excitability.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: cerebellar transcranial direct current stimulation
Description: TDCS is a safe and non-invasive technique for modulating cortical excitability and behavior. TDCS, delivered via surface electrodes, induces an intracerebral current flow sufficient to achieve changes in cortical excitability. Anodal stimulation up-regulates cortical excitability, while cathodal stimulation decreases excitability.
Study: NCT05046860

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dalbavancin
Description: The unit dose of dalbavancin administered via the peripheral venous route will be 1500 mg at each injection with a first injection at Day1, a second injection at Day15 and a third at Day36, which corresponds to 61 days of treatment with dalbavancin.~In case of residual dalbavancin dosage at Day15 lower than 15 mg/L (rare situation) and a minimal inhibitory concentration for dalbavancin of 0.125mg/L (less than 5% of the strains), an injection every 14 days will be necessary, i.e. Day1, Day15, Day29, Day43 and Day57, which corresponds to 71 days of dalbavancin treatment.~Rifampicin should be given orally at a dose of 600 mg on an empty stomach in the morning for patients weighing less than 70 kg and 900 mg on an empty stomach in the morning for patients weighing more than 70 kg.
Study: NCT04915053

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ABG+ Black Garlin
Description: Daily tablet intake during three months

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Crystalline Cellulose
Description: Daily tablet intake during three months
Study: NCT05601206

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stepped collaborative care intervention
Description: Using website that was specifically designed for advanced cancer patient, collaborative with treatment from health professional

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: Usual care from health providers
Study: NCT04300348

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Heel2Toe
Description: Heel to Toe (Heel2Toe) is a device that clips on the shoe and provides an instant auditory feedback (a beep) for each correct step characterized by putting the heel first and it provides data on gait parameters

Intervention type: OTHER
Group type: OTHER
Intervention: No-feedback control group
Description: The control group will follow the same protocol as the Heel2Toe group but the device will not be in feedback mode just in data acquisition mode.
Study: NCT05385601

Intervention type: OTHER
Intervention: eVOG (Mobile VideoOculoGraphy)
Description: * Eyes movements assessed with e-VOG (mobile application developed on an iPad, that uses the face detection features of the front camera to detect and record eye movements).~* Study duration is about 20 minutes, the day the subject performs his standard video-oculography examination in routine care (using Eye-Tracker®T2)

Intervention type: OTHER
Intervention: eVOG (Mobile VideoOculoGraphy)
Description: * Eyes movements assessed with e-VOG (mobile application developed on an iPad, that uses the face detection features of the front camera to detect and record eye movements).~* Study duration is about 20 minutes, the day the subject performs his standard video-oculography examination in routine care (using Eye-Tracker®T2)
Study: NCT05604430

Intervention type: DEVICE
Intervention: 731 Series Ventilator
Description: FDA cleared ventilator indicated for use in the management of acute or chronic respiratory failure or during resuscitation.
Study: NCT06333457

Intervention type: DEVICE
Intervention: VR Cue-Exposure Therapy
Description: Standard VR Cue Exposure Therapy (VR-CET) for the treatment of alcohol dependence
Study: NCT06179992

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: GGED mobile app
Description: The intervention will be done through an app named GGED, which is used to work on the dysfunctional beliefs that are associated with eating disorders. The app is made up of a series of levels comprising the topics that are normally worked on in CBT in relation to eating disorders. At each level, affirmations in the form of beliefs appear on the screen, and the person must accept them if they are functional, adaptive and positive; or reject them if they are dysfunctional, maladaptive and negative.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GGED mobile app
Description: The intervention will be done through an app named GGED, which is used to work on the dysfunctional beliefs that are associated with eating disorders. The app is made up of a series of levels comprising the topics that are normally worked on in CBT in relation to eating disorders. At each level, affirmations in the form of beliefs appear on the screen, and the person must accept them if they are functional, adaptive and positive; or reject them if they are dysfunctional, maladaptive and negative.
Study: NCT05209347

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Carbon Fiber Custom Dynamic Orthosis (CDO)
Description: The carbon fiber custom dynamic orthosis will consist of a semi-rigid foot plate, a posterior carbon fiber strut, and a proximal cuff below the knee.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Carbon Fiber Custom Dynamic Orthosis (CDO)
Description: The carbon fiber custom dynamic orthosis will consist of a semi-rigid foot plate, a posterior carbon fiber strut, and a proximal cuff below the knee.
Study: NCT06202794

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental: Experimental group
Description: TENS will be initiated one hour after surgery. A portable device with two channels will be used (Neurodyn Portable TENS, Ibramed, Amparo, São Paulo, Brazil). This device will deliver a biphasic, asymmetrical, balanced current, with a frequency of 100 Hz and pulse duration of 100 μs. Four electrodes (5x5 cm) will be positioned on the left and right sides of the spine according to the indicated instructions. The assessor will increase the intensity to promote a strong tingling sensation, reaching the patient's maximum tolerance level without causing discomfort. Emission will be applied in a single session of one continuous hour and the patients will be informed that the sensation may decrease over time. Every 10 minutes, the assessor will ask the patient if there is habituation to the current and will increase the intensity if necessary. TENS will be administered only once for one hour.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Comparator: Control group
Description: Sham TENS will be performed using equipment identical in appearance to active TENS (Neurodyn Portable TENS, Ibramed, Amparo, São Paulo, Brazil) specifically designed for this study. The device will emit an electrical current gradually increased during the first 30 seconds, followed by a gradual decrease over the subsequent 15 seconds reaching an intensity of 0 mA. The device will remain inactive during the rest of the application, but will have a flashing light, giving the patient the appearance that it is active. The assessor will inform the patient that it is possible to feel the sensation of the current or not depending on individual characteristics. This type of equipment is validated and has been used in other studies to facilitate the blinding of participants. Both systems will be calibrated using a digital oscilloscope (DPO 7000, Tektronix Inc., Beaverton, OR, USA).
Study: NCT05557747

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cervicothoracic junction mobilization in form of Maitland mobilization
Description: Group A: will receive cervicothoracic junction mobilization mobilization in form of Maitland mobilization to the C7-T1 level, according to their primary movement restriction (for flexion-extension restriction- central PA glide, for rotation restrictions (unilateral PA glide) for 3 sessions/week over 4 weeks periods.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: autogenic muscle Energy Technique
Description: the technique will applied to neck muscles that are prone to get short including anterior, middle and posterior Scaleni, Sternocleidomastoid, Levator Scapulae and upper fibers of the Trapezius muscle.~The AI MET group will given 3-5 repetitions of post isometric relaxation (PIR) (30-50% isometric contraction of the muscle to be stretched for 7-10 seconds, followed by rest period of 5 seconds and then a stretch of 10-60 seconds hold

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physical therapy
Description: conventional physical therapy only in form of: (superficial heat using hot pack for 10 minutes , Isometric Neck Exercises and Dynamic Neck Exercises)) for 3 sessions/week over 4 weeks periods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physical therapy
Description: conventional physical therapy only in form of: (superficial heat using hot pack for 10 minutes , Isometric Neck Exercises and Dynamic Neck Exercises)) for 3 sessions/week over 4 weeks periods

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional physical therapy
Description: conventional physical therapy only in form of: (superficial heat using hot pack for 10 minutes , Isometric Neck Exercises and Dynamic Neck Exercises)) for 3 sessions/week over 4 weeks periods
Study: NCT05030363

Intervention type: DRUG
Group type: OTHER
Intervention: ALDH enzyme supplementation
Description: ALDH enzyme (PICOZYMEQ™)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALDH enzyme supplementation
Description: ALDH enzyme (PICOZYMEQ™)
Study: NCT05497921

Intervention type: DEVICE
Group type: OTHER
Intervention: handLITE LED device
Description: handLITETM is a home use wearable LED phototherapy device. The device consists of a flexible silicone glove that contains red and near infrared light emitting diodes (LEDs) and a controller. The LEDs generate the light. The glove is worn on the hand and is held in place by an adjustable Velcro strap.
Study: NCT05810662

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lactated ringer and dextrose 5%
Description: Fluid use perioperative

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lactated ringer and dextrose 5%
Description: Fluid use perioperative