TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06723353

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visceral Manipulation Therapy
Description: Visceral Manipulation (VM) is a manual therapy consisting of gentle, specifically placed manipulations that encourage normal mobility, tone, and inherent tissue motion of the viscera and their connective tissues. These manipulations can potentially improve the structural integrity of the abdominal cavity and enhance the physiological functioning of the organs. VM will be administered by certified therapists trained in this specialized technique, focusing on reducing the Inter-Recti Distance (IRD) and associated symptoms of DRA.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abdominal Kinesio Taping
Description: Kinesio Taping (KT) involves the application of a thin, stretchable tape over and around muscles to enhance function, reduce inflammation, and support muscles in movement on a 24hr/day basis. It is non-restrictive, allowing for full range of motion. In this study, KT will be applied in a crisscross pattern across the abdomen to support the abdominal muscles affected by DRA, potentially aiding in muscle function and reducing pain and discomfort.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined Visceral Manipulation and Kinesio Taping
Description: This intervention combines Visceral Manipulation and Kinesio Taping to leverage the benefits of both modalities. The combination aims to enhance the functional and structural support of the abdominal region by improving organ function through VM and providing muscular support through KT. This dual approach is hypothesized to offer a synergistic benefit, potentially providing a more effective treatment for reducing IRD and improving overall abdominal function.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Postpartum Core Strengthening Program
Description: The Core Strengthening Program is designed to strengthen the deep core muscles, including the transverse abdominis, multifidus, and the pelvic floor muscles. Exercises will be tailored to accommodate postpartum women and will be progressively adjusted to match improvements in strength and endurance. The program includes supervised training sessions focusing on enhancing core stability, which is crucial for postpartum recovery and long-term spinal and pelvic health.
Study: NCT06722807

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: sutureless, clampless partial nephrectomy
Description: All subjects will undergo a clampless, sutureless robotic partial nephrectomy.
Study: NCT06722573

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Intervention for Emotional Distress(MIED)-normal version
Description: Mindfulness Intervention for Emotional Distress (MIED) program provides standard audio instructions for mindfulness exercises, introduces the nature and law of anxiety, depression, and other emotions, the source of anxiety, depression, and other emotional distress, and the strategies and methods to alleviate emotional distress. These exercises, knowledge and strategies are based on the latest progress in the field of psychological counseling and treatment, and their application in daily life can help alleviate anxiety, depression and other emotional problems.
Study: NCT06723054

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: regular fluoride 220 ppm F mouthwash without erythritol
Description: The participants will be asked to rinse once daily with a regular fluoride 220 ppm F mouthwash without erythritol.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: regular fluoride 220 ppm F mouthwash with erythritol
Description: The participants will be asked to rinse once daily with a regular fluoride 220 ppm F mouthwash with erythritol.
Study: NCT05331586

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remote Exercise
Description: The pregnant women will perform a home-based structured exercise programme. The exercise will be remotely monitored since the first gestational trimester until delivery
Study: NCT05961774

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation
Description: The stimulation point is the lumbar multifidus hotspot. The parameters will be set at frequency 10 Hz, 50 number of pulses, 40 train of stimulation (5 seconds stimulation and 25 seconds inter-stimulation interval). The position of coil will be placed tangentially at 45 degrees on the LM hotspot. The stimulation will be 20 minutes.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neuromuscular electrical stimulation
Description: The neuromuscular electrical stimulation will be set as interferential current 6000 Hz, amplitude 20-50 Hz with scanning mode, duration 20 minutes, intensity to elicit the LM contraction.
Study: NCT06723054

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: high fluoride 500 ppm F mouthwash with erythritol
Description: The participants will be asked to rinse once daily with a high fluoride 500 ppm F mouthwash with erythritol.
Study: NCT06723782

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AMTRIX-D
Description: Use of a decellularized, viro-inactivated, desiccated, and sterile allogeneic amniotic membrane graft to wrap a tendon after release of its adhesions.
Study: NCT05218148

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sintilimab
Description: Sintilimab 200mg was administered as a 30-60 min intravenous (IV) infusion every 3 weeks.3 cycles before surgery and 5 cycles after surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: Trastuzumab was 8mg/kg for the first time, and 6mg/kg for the follow-up. 3 cycles before surgery and 5 cycles after surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-1 plus oxaliplatin
Description: Oxaliplatin 130 mg/m2 was administered IV every 3 weeks. S-1 was given orally twice daily for the first 2 weeks of each 3-week cycle. The S-1 dose was 40 mg for body surface area (BSA) \< 1.25 m2, 50 mg for BSA 1.25 to \<1.5 m2 and 60 mg for BSA ≥1.5 m2.~Body surface area \&lt;1.25m2: Tegio 40mg bid day 1 \~ 14; Body surface area 1.25 \~ \&lt;1.5m2: Tegio 50mg bid day 1 \~ 14; Body surface area ≥1.5m2: Tegio 60mg bid day 1 \~ 14; 3 cycles before surgery and 3 cycles after surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: S-1 plus oxaliplatin
Description: Oxaliplatin 130 mg/m2 was administered IV every 3 weeks. S-1 was given orally twice daily for the first 2 weeks of each 3-week cycle. The S-1 dose was 40 mg for body surface area (BSA) \< 1.25 m2, 50 mg for BSA 1.25 to \<1.5 m2 and 60 mg for BSA ≥1.5 m2.~Body surface area \&lt;1.25m2: Tegio 40mg bid day 1 \~ 14; Body surface area 1.25 \~ \&lt;1.5m2: Tegio 50mg bid day 1 \~ 14; Body surface area ≥1.5m2: Tegio 60mg bid day 1 \~ 14; 3 cycles before surgery and 3 cycles after surgery.
Study: NCT05878548

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: corrective osteotomy and intramedullary telescoping nail for deformed femur and Wagner technique to fix NOF fracture
Description: corrective osteotomy and intramedullary telescoping nail for deformed femur and Wagner technique to fix NOF fracture
Study: NCT05283109

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tumor Associated Antigen Peptide Vaccine P30-EPS Vaccine
Description: Vaccine that includes 3 peptides (EphA2 linked to P30 peptide, pp65 linked to P30 peptide, and Survivin linked to P30 peptide)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hiltonol
Description: Hiltonol® is made up of synthetic (manmade) RNA (ribonucleic acid) and is used as an adjuvant to the vaccine, meaning it is used with the vaccine to stimulate or enhance the activation of your immune system.
Study: NCT05081791

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Training
Description: 12-week exercise training program including a combination of endurance and resistance training for 45 minutes, twice a week.
Study: NCT05007938

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Icotinib
Description: Icotinib is a EGFR ihibitior.
Study: NCT05160896

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Raltitrexed
Description: Raltitrexed 2 mg/m² iv, 15min. day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Irinotecan 180 mg/m² iv, 30 - 90 min. day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab 5 mg/kg, iv, day 1
Study: NCT06424080

Intervention type: PROCEDURE
Group type: OTHER
Intervention: laparoscopic partial nephrectomy
Description: cases amenable for partial nephrectomy

Intervention type: PROCEDURE
Group type: OTHER
Intervention: robotic partial nephrectomy
Description: cases amenable for partial nephrectomy
Study: NCT05112666

Intervention type: DRUG
Intervention: Rivaroxaban (Xarelto, BAY59-7939)
Description: Retrospective cohort analysis using Clinical Practice Research Datalink (CPRD) GOLD and Aurum Hospital Episode Statistics (HES)-linked datasets in UK.

Intervention type: DRUG
Intervention: other DOACs
Description: Retrospective cohort analysis using CPRD GOLD and Aurum HES-linked datasets in UK.

Intervention type: DRUG
Intervention: LMWH
Description: Retrospective cohort analysis using CPRD GOLD and Aurum HES-linked datasets in UK.
Study: NCT05962411

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dress in Professional Attire
Description: Adolescents pretend to be adult e-cigarette buyers by dressing in professional attire.
Study: NCT05160896

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: cetuximab 500 mg/ m² , iv, day 1
Study: NCT05007938

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Befotertinib
Description: An orally available, irreversible, third-generation，mutant-selective epidermal growth factor receptor（EGFR）inhibitor. Befotertinib combine with icotinib means that both drugs will be given together until disease progression or meet the discontinuation criteria.
Study: NCT06426680

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ILB-3101
Description: There are eight escalating dose cohorts.
Study: NCT05981469

Intervention type: DEVICE
Intervention: Cervical Stiffness Assessmenr
Description: The cervical stiffness is assessed by using the licensed, CE-marked Pregnolia System, during a sterile speculum examination. The single-use, sterile Pregnolia Probe is placed on the anterior lip of the cervix at 12 o'clock position and a recording of cervical stiffness is generated over maximum 60 seconds (typically ̴15 seconds) and displayed as Cervical Stiffness Index (CSI) in mbar. The measurement is repeated 3 consecutive times without any time lag.

Intervention type: OTHER
Intervention: Bishop's Score Assessment
Description: Sterile digital vaginal examination to illicit the Bishop's score (0-12).
Study: NCT04963751

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Recovery After Surgery (ERAS) Counseling to Patients
Description: In pediatric and adolescent gynecology (PAG), pre-operative counseling is typically administered to the patient's caregiver rather than directly to the patient. It is possible that direct patient involvement in ERAS pre-operative counseling could be an important factor to improve post-surgical outcomes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Enhanced Recovery After Surgery (ERAS) Counseling to Caregiver
Description: In pediatric and adolescent gynecology (PAG), pre-operative counseling is typically administered to the patient's caregiver rather than directly to the patient. It is possible that direct patient involvement in ERAS pre-operative counseling could be an important factor to improve post-surgical outcomes.
Study: NCT05586789

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ranquilon
Description: Two 1 mg tablets 3 times per day for 28 days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Two tablets 3 times per day for 28 days
Study: NCT04936633

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention by medical staff based on a cloud system
Description: Remote intervention by medical staff (between Visit 1 and Visit 2; Week 2, 4, 6, 8, 10) : analyzing continuous glucose monitoring data for last two weeks in the cloud system~- Intervention contents~1. Diet, exercise pattern~2. Causes of hypoglycemia~3. Causes of hyperglycemia~4. Causes of glycemic variability~5. Counseling for improvement plans for the cause~6. Counseling to strengthen lifestyle modification~7. Counseling for insulin administration~8. Counseling for Insulin dose adjustment (adjusted dose)~9. Counseling for how to use a FSGM
Study: NCT05584280

Intervention type: DEVICE
Intervention: Orsiro stent on shelf
Description: Cluster randomization to Orsiro stent on shelf vs. control

Intervention type: DEVICE
Intervention: Promus stent on shelf
Description: Cluster randomization to Promus stent on shelf vs. treatment
Study: NCT05534698

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PCI
Description: Revascularization by PCI

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CABG
Description: Revascularization by CABG
Study: NCT06175143

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GR2002 injection
Description: TSLP monoclonal antibody

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GR2002 injection
Description: TSLP monoclonal antibody

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GR2002 injection
Description: TSLP monoclonal antibody

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GR2002 injection
Description: TSLP monoclonal antibody
Study: NCT04940832

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: pulsed radiofrequency modulation
Description: a percutaneous needle electrode to apply pulsed RF signals that modulate the activity of sensory nerves. The pulsing of the RF signal permits a maximum temperature to be achieved - usually 42 Celsius. This helps prevent collateral damage from occurring during the procedure and should help reduce procedural complications.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: pulsed radiofrequency modulation
Description: a percutaneous needle electrode to apply pulsed RF signals that modulate the activity of sensory nerves. The pulsing of the RF signal permits a maximum temperature to be achieved - usually 42 Celsius. This helps prevent collateral damage from occurring during the procedure and should help reduce procedural complications.
Study: NCT01324791

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: anti-reflux surgery

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: anti-reflux surgery
Study: NCT06487091

Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of platelet function
Description: Blood withdrawal, platelet separation and analysis of the expression levels of markers of platelet function
Study: NCT04805437

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D TLSO
Description: Brace treatment with Boston 3D 20 hours a day until skeletal maturity.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard TLSO
Description: Brace treatment with standard Boston brace 20 hours a day until skeletal maturity.
Study: NCT06436404

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hammock intervention
Description: It is a hammock made of 100% cotton fabric that prevents heat loss and has an internal apparatus to support the position, which can be adapted to the incubator by the researchers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kangaroo care intervention
Description: In the clinic, the baby will receive kangaroo care with his mother in a quiet room with reduced lighting.
Study: NCT06566937

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-health video
Description: Length: The video is approximately 10-15 minutes long, making it concise and easy to watch in one sitting.~Visuals: Includes engaging visuals, such as animations, graphics, and real-life footage, to illustrate key concepts and keep viewers engaged.~Tone: The tone is supportive, empathetic, and empowering, aiming to create a positive and encouraging atmosphere.
Study: NCT05344495

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: hyalase group
Description: bupivacaine 15 mg 0.5% plus 2 mL normal saline containing 300 international units (IU) hyaluronidase.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: midazolam group
Description: 2 mg midazolam dissolved in 2 ml sterile saline plus 15 mg bupivacaine 0.5%
Study: NCT06405646

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood CB1, CB2, TRPV-1 concentration measurement
Description: In each of the patients blood CB1, CB2, TRPV-1 concentration will be measure

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood CB1, CB2, TRPV-1 concentration measurement
Description: In each of the patients blood CB1, CB2, TRPV-1 concentration will be measure
Study: NCT01424631

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: single incision laparoscopic appendectomy

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: conventional laparoscopic appendectomy
Study: NCT06342661

Intervention type: DIAGNOSTIC_TEST
Intervention: Neuropsychological testing
Description: The primary outcomes were Mini-Mental State Examination and Montreal Cognitive Assessment scores for screening of cognitive decline, which are recommended by NINDS-AIREN. The secondary outcomes included the performance in five cognition domains: (1) verbal memory, Hopkins Verbal Learning Test ; (2) visual-spatial ability, Clock Drawing test; (3) executive function, Trail Making test (TMT) (B time); (4) attention, TMT (A time); and (5) language tests, Boston Naming test2 (BNT-2)

Intervention type: DIAGNOSTIC_TEST
Intervention: Neuropsychological testing
Description: The primary outcomes were Mini-Mental State Examination and Montreal Cognitive Assessment scores for screening of cognitive decline, which are recommended by NINDS-AIREN. The secondary outcomes included the performance in five cognition domains: (1) verbal memory, Hopkins Verbal Learning Test ; (2) visual-spatial ability, Clock Drawing test; (3) executive function, Trail Making test (TMT) (B time); (4) attention, TMT (A time); and (5) language tests, Boston Naming test2 (BNT-2)
Study: NCT05915507

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pranayama plus acupoint stimulation by laser
Description: This group will receive 3-session per-week laser stimulation (for eight weeks) to some selected acupoints and daily pranyama exercises (nearly every session will be one hour), the stimulated bilateral acupoints will be (LI 19, LI 20, ST2, and ST4. ST6, ST7, ST17, ST36, SI18, BL2, GB14, GV24 and EXHN5). Every acupoint will be stimulated with laser power of 100 mw that will be used on a spot area of 1 cm2 for 1 minute.~this group will receive also pranayama session (applied daily, one hour approximately, for eight weeks) composed from (alternate nostril pranayama, diaphragmatic pranayama, rapid abdominal pranayama, Bhramari pranayama )

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: acupoint stimulation by laser
Description: This group will receive 3-session per-week laser stimulation (for eight weeks) to some selected acupoints, the stimulated bilateral acupoints will be (LI 19, LI 20, ST2, and ST4. ST6, ST7, ST17, ST36, SI18, BL2, GB14, GV24 and EXHN5). Every acupoint will be stimulated with laser power of 100 mw that will be used on a spot area of 1 cm2 for 1 minute.
Study: NCT06182410

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Defibrotide
Description: Given intravenously (IV)
Study: NCT05234073

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SEE Learning Online Training
Description: This intervention includes classes about socioemotional learning theory and practice, topics related to ethics and well-being practices

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SEE Learning Online Training
Description: This intervention includes classes about socioemotional learning theory and practice, topics related to ethics and well-being practices

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Waiting list
Description: This group will wait for one month to receive SEE Learning Online Training
Study: NCT06404294

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: External Diaphragm Pacemaker treatment
Description: On the basis of conventional treatment, the patients in this group were treated with external diaphragm pacemaker for 2 weeks or until extubation.The treatment process of external diaphragm pacemaker is as follows: Set parameters: pacing frequency: 5-9 times /min, generally starting from 5 times /min, and adjusted according to the tolerance of the child; Pulse frequency 30 hertz; The stimulation intensity generally starts from 2-3. If the respiratory waveform of the child on the machine is not disturbed, it indicates that the child can tolerate it and the intensity can be appropriately increased. Treatment time: generally starts from 5 minutes, the longest is not more than 20 minutes, the frequency of treatment: 1 time/day in the first week, 2 times/day in the second week.
Study: NCT05159466

Intervention type: PROCEDURE
Intervention: Kidney transplant
Description: Participants will be recruited at the Tulane Abdominal Transplant Institute site where they are evaluated and followed for organ transplantation as part of standard of care. HIV-positive adult candidates on the wait list or referred for organ transplantation evaluation willing to accept an HIV positive organ will be recruited.

Intervention type: PROCEDURE
Intervention: Kidney transplant
Description: Participants will be recruited at the Tulane Abdominal Transplant Institute site where they are evaluated and followed for organ transplantation as part of standard of care. HIV-positive adult candidates on the wait list or referred for organ transplantation evaluation willing to accept an HIV positive organ will be recruited.
Study: NCT04744922

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Extracts of citrus peels standardized in AUR and NAR (phytocomplex).
Description: One capsule a day for 9 months

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Extracts of citrus peels standardized in AUR and NAR (phytocomplex).
Description: One capsule a day for 9 months
Study: NCT05028452

Intervention type: OTHER
Group type: OTHER
Intervention: Internet based support
Description: Carer eSupport is designed to prepare informal caregivers for caregiving, to decrease caregiver burden and prevent a deteriorated health.
Study: NCT04715529

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FZJ-003
Description: Subjects will receive FZJ-003 oral capsules in a dose escalation format.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will receive placebo oral capsules (matching FZJ-003) in a dose escalation format .