TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04764799

Intervention type: PROCEDURE
Intervention: Rapid sequence induction
Description: Rapid sequence induction starts with the administration of rapid acting intravenous narcotics, opioids and neuromuscular blockage and avoids whenever possible positive-pressure ventilation after induction of anesthesia.

Intervention type: PROCEDURE
Intervention: Rapid sequence induction
Description: Rapid sequence induction starts with the administration of rapid acting intravenous narcotics, opioids and neuromuscular blockage and avoids whenever possible positive-pressure ventilation after induction of anesthesia.
Study: NCT06577610

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback from colonoscopy monitoring program
Description: Adenoma detection rate feedback from colonoscopy monitoring programs
Study: NCT05759026

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Accompaing cares
Description: After signing the consent form, the patient will be randomised. The ones randomised in VR groups will choose their preferred environment (e.g. landscapes, animals...).~The participant will be managed during 1 care (one care in control condition (no material used), care with the VR headset, one care with the VR set and the prefered environnent of the patient) for an average of 30 minutes (including the completion of the scales and questionnaires).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Accompaing cares
Description: After signing the consent form, the patient will be randomised. The ones randomised in VR groups will choose their preferred environment (e.g. landscapes, animals...).~The participant will be managed during 1 care (one care in control condition (no material used), care with the VR headset, one care with the VR set and the prefered environnent of the patient) for an average of 30 minutes (including the completion of the scales and questionnaires).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Accompaing cares
Description: After signing the consent form, the patient will be randomised. The ones randomised in VR groups will choose their preferred environment (e.g. landscapes, animals...).~The participant will be managed during 1 care (one care in control condition (no material used), care with the VR headset, one care with the VR set and the prefered environnent of the patient) for an average of 30 minutes (including the completion of the scales and questionnaires).
Study: NCT06141226

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2450 +Anlotinib+Docetaxel
Description: TQB2450 is a humanized monoclonal antibody targeting programmed death ligand 1 (PD-L1), which prevents PD-L1 from binding to PD-1 and B7.1 receptors on the surface of T cells, restoring T cell activity and enhancing immune response. It has the potential to treat various types of tumors.~Anlotinib is a multi target receptor tyrosine kinase (RTK) inhibitor. It can inhibit VEGFR1, VEGFR2, VEGFR3, c-Kit, PDGFR β Activity.~Docetaxel is a taxane based anti-tumor drug.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: TQB2450 +Androtinib Placebo+Docetaxel
Description: TQB2450 is a humanized monoclonal antibody targeting programmed death ligand 1 (PD-L1), which prevents PD-L1 from binding to PD-1 and B7.1 receptors on the surface of T cells, restoring T cell activity and enhancing immune response. It has the potential to treat various types of tumors.~Androtinib Placebo Docetaxel is a taxane based anti-tumor drug.
Study: NCT04608552

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: OMT Exercises
Description: Oral and oropharyngeal exercises

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Nasal Breathing Exercises
Description: Nasal breathing exercises each week

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Use of Nasal Lavage
Description: Use of nasal lavage with application of 10ml of saline in each nostril two times per day
Study: NCT05743335

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JCXH-221
Description: Participants will be randomized to either placebo or JCXH-221 for Phase 1. For Phase 2, participants will either be randomized to JCXH-221 or a FDA approved Active comparator.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be randomized in Phase 1 to either JCXH-221 or placebo
Study: NCT04701762

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GlideScope videolaryngoscope (Verathon, Bothell, Washington 98011)
Description: After confirming adequate muscle relaxation, initial laryngoscopy will be performed using GlideScope videolaryngoscope with an appropriately sized blade (usually size 3 or 4). The GlideScope (Verathon, Bothell, Washington 98011) is an FDA-cleared commercially available portable videolaryngoscope.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Direct laryngoscopy
Description: After confirming adequate muscle relaxation, initial laryngoscopy will be performed using direct laryngoscopy with an appropriately sized Macintosh or Miller blade (usually size 3 or 4);
Study: NCT06500338

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: free-fall
Description: The aircraft will fly in parabolas that initially produce increased gravity (1.8-G, hypergravity), followed by \~20-50 second periods of partial gravity or weightlessness. Flights which produce partial gravity (0.25-, 0.50-, and 0.75-gravity) generally will consist of 31 parabolas (at least 10 parabolas at each gravity level), and flights that produce weightlessness generally will consist of 16 parabolas.
Study: NCT05180227

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DS8R
Description: transcutaneous stimulation of the spinal cord.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Orthostatic tilt
Description: perform an orthostatic tilt without and with stimulation.

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Orthostatic tilt
Description: perform an orthostatic tilt without and with stimulation.
Study: NCT06651944

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Invisalign® System with mandibular advancement featuring occlusal blocks
Description: Class II correction using the Invisalign® System with mandibular advancement featuring occlusal blocks
Study: NCT06652932

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low temperature (16°C) group
Description: The exposure group will be exposed to low temperature (16°C) in a chamber for about 2 hours, resting during the whole periods.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate temperature (22°C) group
Description: The exposure group will be exposed to thermoneutral temperature (22°C) in a chamber for about 2 hours, resting during the whole periods.
Study: NCT06654869

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: lauhgter yoga
Description: include laughter yoga effects on cancer patients' symptom management
Study: NCT06655246

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ziftomenib
Description: menin inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ziftomenib
Description: menin inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ziftomenib
Description: menin inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: imatinib mesylate
Description: kinase inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: imatinib mesylate
Description: kinase inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: imatinib mesylate
Description: kinase inhibitor
Study: NCT06655311

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Enlicitide Chloride
Description: Oral administration

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral administration
Study: NCT04789070

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sirolimus
Description: Sirolimus is a currently licensed drug primarily used for immunosuppression post-kidney transplantation to prevent organ rejection. Sirolimus was initially considered as a treatment in IBM for its immunosuppressive action and beneficial effects in an experimental myositis mouse model.(11) Transfer of effector T cells from affected to healthy animals resulted in myositis, but the presence of Treg cells were protective against development of myositis. As Sirolimus, which acts to deplete effector T cells but preserving the Treg cells, was effective in this mouse model of myositis, it was therefore postulated that it may also be effective in IBM, not only for its effects on effector T cells and Treg cells, but also for its additional effects on protein degradation.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06586034

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Impacto (Mobile App)
Description: This is the mobile app to be developed and evaluated in this project. It is designed for both English and Spanish languages and is culturally tailored for Hispanic/Latino/Latinx individuals who smoke. Impacto will be developed for both iOS and Android platforms. The mobile app aims to aid smoking cessation by targeting elevated anxiety sensitivity.
Study: NCT06593119

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telemedicine management of Hypertension
Description: TM-HTN intervention includes tailored and frequent self-management support, home blood pressure monitoring, pharmacotherapy, and as-needed assistance for health-related social needs provided by pharmacists, nurses, community health workers, and social workers. This will be compared with usual care

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: This includes usual clinic based HTN care using routinely available clinic resources (e.g., community health worker, social worker). Clinicians can offer self-management support (e.g., dietician referral) or recommend a home BP monitor. These activities mirror current primary care practice.
Study: NCT06594419

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Mother Healthy Baby Toolkit
Description: Customized bowl with markings to indicate the recommended amount of food that participants should consume in pregnancy and while exclusively breastfeeding in the first 6 months, as well as how much they should feed their babies at 6-8 months, 9-12 months, and 1-2 years respectively. The toolkit also includes a spoon used to test and ensure adequate thickness of the meals fed to infants \>6mos and a counseling card that indicates the frequency of meals, recommended food groups for meeting daily nutrient needs, and hand hygiene and hygienic food preparation

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: The Ethiopian government and Saving Little Lives Initiative (SLL) standard of care includes maternal and infant nutrition education and counseling, iron and folic acid supplementation, as well as training on effective Kangaroo Mother Care (KMC), primarily defined as exclusive breastfeeding and skin-to-skin contact ≥ 8 hours per day-in the event of Low birth weight (LBW) or preterm delivery.
Study: NCT06589336

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary changes via Instacart vouchers
Description: Instacart will provide consumers with the dignity of choice to shop at preferred retail stores, which is key for our behavioral change strategy. Delivery and service fees will be waived for patients, so 100% of the vouchers will be applied to groceries (all food products excluding alcohol and tobacco). The investigators will use a custom study store front with an integrated website and email option.

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary changes via Instacart vouchers
Description: Instacart will provide consumers with the dignity of choice to shop at preferred retail stores, which is key for our behavioral change strategy. Delivery and service fees will be waived for patients, so 100% of the vouchers will be applied to groceries (all food products excluding alcohol and tobacco). The investigators will use a custom study store front with an integrated website and email option.

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary changes via access to Mid-Ohio Farmacy
Description: Mid-Ohio Farmacy will provide healthy food provisions through a network of food banks with fresh produce and other items.

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary changes via access to Mid-Ohio Farmacy
Description: Mid-Ohio Farmacy will provide healthy food provisions through a network of food banks with fresh produce and other items.

Intervention type: OTHER
Group type: OTHER
Intervention: Behavior changes via access to Health Impact Ohio Hub
Description: Health Impact Ohio Hub is a regional coordination entity that has connections with community care agencies that employ community health workers to assess social needs and make connections to resources to address social needs. The community health workers will conduct an initial needs assessment, and guide the participant through appropriate care pathways to address social needs.

Intervention type: OTHER
Group type: OTHER
Intervention: Behavioral nutrition counseling
Description: All dietary recommendations will be individualized and informed by existing guidelines to improve diet quality and cardiovascular health through the Mediterranean Diet.

Intervention type: OTHER
Group type: OTHER
Intervention: Cooking classes
Description: Registered dietician nutritionists will also lead cooking demonstrations every 2 weeks, focused on culinary education and building engagement among SUSTAIN participants.

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary changes to Delivery fees
Description: Delivery fees will be supported for SUSTAIN participants.

Intervention type: OTHER
Group type: OTHER
Intervention: Dietary changes to Delivery fees
Description: Delivery fees will be supported for SUSTAIN participants.
Study: NCT06594003

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency
Description: There has recently been considerable interest in the role of radiofrequency ablation (RFA) of the genicular nerves for KOA. In the majority of previous studies, ablation was done via a radiofrequency technique using either fluoroscopy or ultrasound for only three genicular nerves, whereas the knee joint is also supplied by a few other nerves . Interestingly, neurolytic agents can also be used to ablate the nerves, and are readily available, less costly, and need less logistic support

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency
Description: There has recently been considerable interest in the role of radiofrequency ablation (RFA) of the genicular nerves for KOA. In the majority of previous studies, ablation was done via a radiofrequency technique using either fluoroscopy or ultrasound for only three genicular nerves, whereas the knee joint is also supplied by a few other nerves . Interestingly, neurolytic agents can also be used to ablate the nerves, and are readily available, less costly, and need less logistic support
Study: NCT06602310

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Web based preoperative assessment
Description: Preoperative assessment conducted through a web based application. Telematic non-face-to-face preoperative assessment.
Study: NCT06594081

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention podcasts
Description: Students in the experimental group will listen to podcasts.
Study: NCT06596239

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: lower-clear-plate-based intermaxillary traction (LCP-IMT)
Description: The patient is instructed to apply elastics between the upper molar bands and the hooks on the lower clear plates.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Removable mandibular retractor (RMR)
Description: An appliance is worn on the upper jaw, which affects the lower jaw by using an inferiorly extended labial bow.
Study: NCT06601816

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: maxillary sinus lift with reamer
Description: Lateral window created with specially designed burs for lateral sinus lift

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: maxillary sinus lift with piezzo
Description: lateral window was created using piezo surgery and surgical guide

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: maxillary sinus lift with conventional burr
Description: the lateral window was created with conventional rotary instrument burs
Study: NCT06601803

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: sterile saline solution
Description: The shoulder will be washed with normal sterile saline before and after placing the shoulder implant

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Surgiphor
Description: The shoulder will be washed with Surgiphor (Povidone Iodine) before and after placing the shoulder implant

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sample Collection
Description: During the surgical procedure, 4 swabs of the surgical wound will be taken at various times throughout the procedure

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sample Collection
Description: During the surgical procedure, 4 swabs of the surgical wound will be taken at various times throughout the procedure
Study: NCT06590311

Intervention type: DIAGNOSTIC_TEST
Intervention: Heart Rate Variability
Description: Heart rate variability evaluation through different domains

Intervention type: DIAGNOSTIC_TEST
Intervention: Heart Rate Variability
Description: Heart rate variability evaluation through different domains
Study: NCT06603025

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chewing gum
Description: Preoperative intervention group patients will chew sugarless gum for at least 30 minutes 30-60 minutes before surgery. The gum will be removed before going to the operating room.
Study: NCT06600204

Intervention type: OTHER
Intervention: lung scintigraphy
Description: Use the SPECT/CT to predict pulmonary function
Study: NCT06653959

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active Transcranial Magnetic Stimulation
Description: Based on each individual's MRI data, individualized stimulation targets will be found, and then this will be used for stimulation for 5 consecutive days.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: sham Transcranial Magnetic Stimulation
Description: Based on each individual's MRI data, individualized stimulation targets will be found, and then this will be used for sham stimulation for 5 consecutive days.
Study: NCT06655506

Intervention type: COMBINATION_PRODUCT
Intervention: ERAS group
Description: This group will include patients that achieved a compliance rate that exceeded 80% of the required predetermined criteria of ERAS protocols.

Intervention type: COMBINATION_PRODUCT
Intervention: Control group
Description: This group will include patients that do not follow the predetermined criteria of ERAS protocols
Study: NCT06655051

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: endoscopic retrograde biliary drainage (single plastic stent)
Description: Participants will undergo ERCP. A flexible tube is inserted into the duodenum, crossing the sphincter of Oddi to access the biliary system. And the location, diameter, and length of biliary stricture will be evaluated by injection of contrast media. A single plastic stent is then placed across the biliary stricture, allowing the bile duct to resume drainage. The participants will be observed closely after ERCP and record complications. Imaging evaluation will be conducted 6 months after stenting to confirm spontaneous passage of the biliary duct stent, and the stent will be removed via ERCP if it is still in place.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: endoscopic retrograde biliary drainage ( fully covered self-expanding metal stent)
Description: Participants will undergo ERCP. A flexible tube is inserted into the duodenum, crossing the sphincter of Oddi to access the biliary system. And the location, diameter, and length of biliary stricture will be evaluated by injection of contrast media. A fully covered self-expanding metal stent is then placed across the biliary stricture, allowing the bile duct to resume drainage. The participants will be observed closely after ERCP and record complications. Imaging evaluation will be conducted 6 months after stenting to confirm spontaneous passage of the biliary duct stent, and the stent will be removed via ERCP if it is still in place.
Study: NCT06600139

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Collaboration-Screening-Referral (SSH) model
Description: The SSH aims to identify parents in need of mental health support and to strengthen social workers' competence in addressing mental illness. The SSH includes three components: 1) Collaborating - establishing collaboration with local services offering support to adults with mental illness, 2) Screening - using screening instruments for depression (the Patient Health Questionnaire - PHQ-9) and anxiety (GAD-7) to identify symptoms of mental illness among parents, and 3) Referral - Discussing the results of the screening with parents and referring to appropriate services. Techniques from motivational interviewing are included. Social workers receive training and material to administer the screening and refer parents in need of support.
Study: NCT06604130

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Prostate cancer screening decision
Description: The subjects would receive serum PSA test.