TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05917002

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Real TBS to mPFC
Description: This will be delivered with the Magventure MagPro System; (double blinded using the integrated active sham system).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham TBS to mPFC
Description: This will be delivered with the Magventure MagPro System; (double blinded using the integrated active sham system). The Magventure MagPro system has an integrated active sham that passes current through two surface electrodes placed on the scalp. The electrodes are placed on the left frontalis muscle under the coil for both the real and sham stimulation sessions.
Study: NCT04932694

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core stabilization training
Description: Exercise training will be given to the participants in the study group in the form of core training exercises for 8 weeks.
Study: NCT05183594

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: TSupport (a Traditional Chinese Medicine)
Description: TSupport is made up of 11 Chinese medicinal herbs.
Study: NCT05375838

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1073
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1073
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1073
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1010
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1010
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273
Description: Sterile liquid for injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection
Study: NCT05340816

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Lymphatic Drainage
Description: Manual lymphatic drainage will apply to the neck, abdominal, bilateral inguinal lymph nodes, bilateral anterior/posterior thighs, and lumbal area. Treatment duration will be approximately 30 minutes for 5 days.
Study: NCT06464146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IN fentanyl
Description: IN fentanyl (1.5 µg/kg)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IN ketamine
Description: IN ketamine (1 mg/kg)
Study: NCT05340816

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Electrical Nerve Stimulation
Description: Transcutaneous electrical nerve stimulation will be apply to abdominal and lumbal area as 100 Hz and 100 msn. Treatment duration will be approximately 20 minutes for 5 days.
Study: NCT06464146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NaCl 0,9 %
Description: Injectable solution used as Placebo of Oral morphine or IN fentanyl/ ketamine.
Study: NCT05367921

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Measurement of compartment compressibility
Description: Application of the CPM#1 device for compartment compressibility ratio measurement - 4 measurements on both legs of each healthy volunteer will be performed
Study: NCT05049122

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab SAR231893
Description: Pharmaceutical form: solution for injection Route of administration: subcutaneous (SC)
Study: NCT04926870

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: picture archiving and communication system
Description: PACS administration during teaching

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional
Description: Clinical experience administration during teaching without PACS
Study: NCT04719533

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pre-marking of episiotomy location
Description: A template marking the pre-determined correct location of episiotomy will be used to mark to women in the interventional group
Study: NCT06135766

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A Lust for Life
Description: A Lust for Life (ALFL) is a universal teacher-led programme which aims to build resilience, increase wellbeing, and enhance emotional literacy of 8-13 year old school children. The programme spans ten 40-minute classes. The ALFL curriculum draws on multiple sources including contemporary positive psychology; traditional, second, and third wave cognitive behaviour therapy (CBT); and developmental, educational, and health psychology. In ALFL children learn the following specific self-regulation skills: naming and rating the intensity of emotions; linking thoughts, feelings and actions; mindfulness; breathing exercises; visualization exercises; progressive muscle relaxation; positive self-talk (gratitude, optimism, and cognitive restructuring); obtaining social support from adults and peers; assertiveness; managing bullying; and using the internet safely. Skills are learned through didactic instruction, video modelling, in-class experiential exercises, and homework practice.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Waiting List Control
Description: Control group placed on a 12-week waiting list for the A Lust for Life (ALFL) programme.
Study: NCT06460935

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sexual health training
Description: The 20-hour sexual health training will be given online for 5 weeks. Case discussions using the Plissit Model will be held in the training content.
Study: NCT04729010

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture to treat anxiety in Parkinson disease
Description: Subjects will be randomized in a 1:1 ratio to receive sham acupuncture.
Study: NCT06464146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NaCl 0,9 %
Description: Injectable solution used as Placebo of Oral morphine or IN fentanyl/ ketamine.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NaCl 0,9 %
Description: Injectable solution used as Placebo of Oral morphine or IN fentanyl/ ketamine.
Study: NCT06114082

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IDA-TACE
Description: Stable chemoemulsion will be produced by dissolving 10 mg of idarubicin powder (Zavedos; Pfizer, New York, NY, USA) in 2.5 mL of an iodinated contrast agent. This solution will then be mixed with 10 mL of iodized oil (Lipiodol Ultrafluid; Guerbet, Villepinte, France) using a three-way stopcock. This chemoemulsion will be prepared in aliquots (0.8 mL of chemoemulsion in each 1 mL syringe) and injected until the embolization endpoint is achieved.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: DOX-TACE
Description: Stable chemoemulsion will be produced by dissolving 50 mg of doxorubicin powder (Adriamycin RDF; Ildong Pharmaceutical, Seoul, Republic of Korea) in 2.5 mL of an iodinated contrast agent. This solution will then be mixed with 10 mL of iodized oil (Lipiodol Ultrafluid; Guerbet, Villepinte, France) using a three-way stopcock. This chemoemulsion will be prepared in aliquots (0.8 mL of chemoemulsion in each 1 mL syringe) and injected until the embolization endpoint is achieved.
Study: NCT05079035

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TTAX03
Description: Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: 2 mL Sterile, preservative free 0.9% NaCl
Study: NCT06195813

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Asparagus capsule
Description: Asparagus capsule is categorized as dietary supplement.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsule
Description: Placebo capsule is categorized as other.
Study: NCT05996315

Intervention type: OTHER
Intervention: Hematoma block
Description: A patient who presents to the emergency department with a suspected distal end radius fracture , will be sent for an x-ray. If the X ray-shows a distal end radius fracture a decision to give hematoma block will be taken as per the choice of the treating physician. Patients who do not meet the exclusion criteria are excluded from the study at this phase.

Intervention type: OTHER
Intervention: Supracondylar radial nerve block
Description: A patient who presents to the emergency department with a suspected distal end radius fracture will be assessed with a baseline NRS score1 and given analgesics if needed. Further they will be sent for an x-ray. If the X ray-shows a distal end radius fracture a decision to give supracondylar radial nerve block will be taken as per the choice of the treating physician. Patients who do not meet the exclusion criteria are excluded from the study at this phase.
Study: NCT04729010

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Acupuncture to treat anxiety in Parkinson disease
Description: Subjects will be randomized in a 1:1 ratio to receive sham acupuncture.
Study: NCT04883190

Intervention type: OTHER
Intervention: Fulfilling Questionaires
Description: Fulfilling Questionaires PHQ-D (brief) and FSMC

Intervention type: OTHER
Intervention: Fulfilling Questionaires
Description: Fulfilling Questionaires PHQ-D (brief) and FSMC
Study: NCT06471894

Intervention type: RADIATION
Intervention: Magnetic resonance imaging scanning
Description: Perform brain diffusion imaging, magnetic resonance spectroscopy, and functional magnetic resonance imaging scans on all individuals

Intervention type: RADIATION
Intervention: Magnetic resonance imaging scanning
Description: Perform brain diffusion imaging, magnetic resonance spectroscopy, and functional magnetic resonance imaging scans on all individuals

Intervention type: RADIATION
Intervention: Magnetic resonance imaging scanning
Description: Perform brain diffusion imaging, magnetic resonance spectroscopy, and functional magnetic resonance imaging scans on all individuals

Intervention type: DRUG
Intervention: FMT Protocol
Description: Treatment of disease groups (UC and CD) using prepared fecal microbiota transplantation solution

Intervention type: DRUG
Intervention: FMT Protocol
Description: Treatment of disease groups (UC and CD) using prepared fecal microbiota transplantation solution
Study: NCT05436951

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief on-shift nap
Description: The brief nap opportunity will allow for a 45-minute nap between the hours of 0200 and 0300 during the in-lab 12-hour simulated night shift.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief on-shift nap
Description: The brief nap opportunity will allow for a 45-minute nap between the hours of 0200 and 0300 during the in-lab 12-hour simulated night shift.
Study: NCT06137716

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Training with a Robotic Hand Exoskeleton
Description: The rehabilitation program extended over six consecutive weeks. Each therapy session, lasting 45 minutes, occurred four times per week, resulting in a total of 24 sessions. Within each session, a total of six exercises, consisting of three passive exercises and three bilateral exercises, were performed in an alternating manner. The exercises were executed in the following sequence: 1) Bilateral hand opening and closing; 2) Passive independent finger opening and closing; 3) Bilateral pinch; 4) Passive hand opening and closing; 5) Bilateral hand opening and closing based on a VR-based game involving squeezing an orange; 6) Passive pinch.
Study: NCT06375759

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subarachnoid-Subarachnoid (S-S) Bypass
Description: The dura was widely exposed beyond the level of trauma, and then a midline dural opening was made under an operative microscope. When dura and arachnoid were adhered because of an expansion of arachnoiditis, they had to be released with great care to place the bypass tubes. During this procedure, S-S bypass was not usually needed to performed arachnoid lysis. This exposure had to reach the normal arachnoid mater free from arachnoiditis and adhesion, with normal CSF circulation.~After dissections of the normal arachnoid mater at the cephalic and caudal sites, 1 or 2 tubes made of medical grade silicone (ventricular drainage tube; internal diameter 1.5-2.0 mm, external diameter 2.5-3.3 mm) were inserted into the cephalic and caudal ends of the normal subarachnoid space. The part of the tube inserted into the subarachnoid space was approximately 2 cm long.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intradural Adhesion Lysis
Description: Intradural spinal cord Adhesion Lysis
Study: NCT04697589

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Memophenol 300 mg
Description: 300 mg a proprietary, standardized botanical blend rich in polyphenols (SBRP) and especially in monomers of flavanols.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Memophenol 600 mg
Description: 600 mg a proprietary, standardized botanical blend rich in polyphenols (SBRP) and especially in monomers of flavanols.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Colored maltodextrin
Study: NCT04715763

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Telmisartan Oral Product
Description: Angiotensin Receptor Blocker (ARB) FDA approved for use in hypertension and for cardiovascular risk reduction

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Gelatin capsules filled with an inactive ingredient
Study: NCT05083104

Intervention type: DIAGNOSTIC_TEST
Intervention: laboratory investigations on coagulation profiles
Description: CBC ,PT ,aPTT ,Protein C .Protein S ,ATIII and vWF

Intervention type: DIAGNOSTIC_TEST
Intervention: laboratory investigations on coagulation profiles
Description: CBC ,PT ,aPTT ,Protein C .Protein S ,ATIII and vWF
Study: NCT06189651

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wrist splint
Description: The same type of wrist splint to be used for at least 8 hours at night for 4 weeks, to be worn in a neutral position and in accordance with the wrist as described in previous studies to restrict movement in the wrist. Patients who did not sleep for 8 hours were asked to complete 8 hours of wrist splint use before going to sleep or after waking up.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wrist splint
Description: The same type of wrist splint to be used for at least 8 hours at night for 4 weeks, to be worn in a neutral position and in accordance with the wrist as described in previous studies to restrict movement in the wrist. Patients who did not sleep for 8 hours were asked to complete 8 hours of wrist splint use before going to sleep or after waking up.
Study: NCT05577390

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intraneural Facilitation Therapy Treatment
Description: Intraneural Facilitation Therapy uses three manual holds to bias blood flow to closed endoneurial capillaries. The first is the facilitation hold, which is thought to pressurize the nervous system and bias circulation from the artery into the epineurium. This hold stretches the nerve further than the artery, increasing the amount of elastin in the artery and enlarging the opening of the arterial junction increasing blood into the epineurium. The secondary hold then increases epineurial blood into the transperineurial vessels increasing pressure into the endoneurial capillaries of the site being treated. The third hold, known as the sub hold, encourages blood flow through ischemic endoneurial capillaries that have increased resistance/pressure through the application of Bernoulli's principle. The series of stretches will be repeated on the affected side for the treatment duration.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Physical Therapy Treatment
Description: The standard physical therapy treatment includes muscle stretching, balance, and strengthening exercises known to improve neuropathy symptoms.
Study: NCT06486532

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HeartBeet Clinic
Description: 16 weeks of group based lifestyle medicine coaching covering the six pillars of lifestyle medicine. The six pillars of lifestyle medicine include regular physical activity; a whole-food plant-based diet; restorative sleep; limiting substance use (e.g., tobacco and alcohol use); having meaningful social connections; and stress management. Groups will be led by clinician or health coach expert.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-paced education
Description: Self-paced course and workbook with no contact with study clinician or health coach expert
Study: NCT05637801

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sensory Stimulation System (GS120) - Active
Description: Sensory Stimulation System (GS120) - Active settings

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sensory Stimulation System (GS120) - Sham
Description: Sensory Stimulation System (GS120) - Sham settings
Study: NCT03753204

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furosemide 40 mg
Description: Blood pressure data from the monitors will be downloaded and the average of the systolic blood pressure of the day of salt loading, from 12 noon (end of the saline infusion) until 10 pm will be used as the BP for the salt-loading period of study. The average of the systolic blood pressure of the day of salt depletion, from 12 noon (second dose of furosemide) until 10 pm will be used as the BP for the salt-depleted period of study. A fall in systolic BP ≥10 mm Hg from the salt-loading to the salt-depletion periods will be used to classify a subject as salt sensitive.
Study: NCT04479475

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supportive care through community support persons
Description: The adapted B-SBNT involves families and the wider social networks of people receiving MMT to support recovery. Key components of the intervention include: mapping the social networks of clients; inviting others identified through the mapping to participate in the intervention; building communication strategies with network members; and developing joint activities with network members, e.g., income-generating activities. MMT client participants attend seven sessions over the course of six weeks: (1) Introduction, (2) Working in a social network-based setting, (3) Setting drinking and drug use goals, (4) Coping skills 1, (5), Coping Skills 2, (6) Making lifestyle changes, (7) Generating income. Social support persons attend up to five sessions over the course of six weeks.
Study: NCT06189651

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 5% dextrose injection using USG-guided nerve hydrodissection method
Description: 2 ml each of 5% dextrose injection was administered once at the proximal wrist level above the median nerve separating the median nerve from the flexor retinaculum and below the median nerve separating the median nerve from the flexor tendons by nerve hydrodissection method in the transverse inplane plane under ultrasound guidance. After the application, the spread of the injectate was observed by looking longitudinally at the median nerve.
Study: NCT06228547

Intervention type: OTHER
Intervention: Questionnaire
Description: Standardized questionnaire specifically made for the study. The interview lasts approximately 15 minutes. The form gathers baseline characteristics of the patients such as socio-demographic information, symptoms, lifestyle factors and gynecological history. The questionnaire focuses also on the manner in which the diagnosis was revealed to the patient and their experience of this disclosure. Lastly, the questionnaire includes items issued from French practice guidelines concerning etiological investigations, fertility assessment, osteoporotic and cardiovascular complications, HRT use, and residual symptoms
Study: NCT05281185

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Extended half-life FVIII concentrates with PK-guided dosing
Description: Extended half-life FVIII concentrates with PK-guided dosing as low-dose factor replacement prophylaxis (10-20u/kg, 2-3 times/week) for 6 months in severe haemophilia A patients that previously receive weight-based factor replacement prophylaxis

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard half-life FVIII concentrates with weight-based dosing
Description: standard half-life FVIII concentrates with weight-based dosing, that current patients' regimen before enrolling in this study
Study: NCT04997785

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided Pericapsular Nerve Group (PENG) Block
Description: PENG blocks is performed by Emergency Medicine board-certified emergency physicians (EPs) with standard training program. PENG block is performed using a spinal needle (NIPRO® 21G × 70 mm) at the level of of anterior superior iliac spine, parallel to the inguinal crease, with real-time ultrasound guidance, according to the steps published by Girón-Arango et al in 2018. The investigators use 20 ml of 1% lidocaine for nerve block because this drug has a short onset time, which is adequate to relieve pain before surgical intervention.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided Pericapsular Nerve Group (PENG) Block
Description: PENG blocks is performed by Emergency Medicine board-certified emergency physicians (EPs) with standard training program. PENG block is performed using a spinal needle (NIPRO® 21G × 70 mm) at the level of of anterior superior iliac spine, parallel to the inguinal crease, with real-time ultrasound guidance, according to the steps published by Girón-Arango et al in 2018. The investigators use 20 ml of 1% lidocaine for nerve block because this drug has a short onset time, which is adequate to relieve pain before surgical intervention.
Study: NCT06292065

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Point-of-care gastric ultrasound
Description: Using ultrasound to visualise the gastric antrum in supine position and right lateral decubitus.