TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06603376

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOLFIRI + Vemurafenib + Cetuximab
Description: Liposomal Irinotecan Hydrochloride Injection (II): 60 mg/m², intravenous infusion over at least 90 minutes, on day 1; Leucovorin: 400 mg/m², intravenous infusion over 2 hours, on day 1; 5-FU: 400 mg/m², intravenous bolus; 5-FU: 2400 mg/m², continuous infusion over 46-48 hours, on day 1; Cetuximab: 500 mg/m², intravenous infusion over at least 2 hours, on day 1; Vemurafenib: 720 mg, orally twice daily. Repeat every 2 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FOLFIRI ± Bevacizumab
Description: Liposomal Irinotecan Hydrochloride Injection (II): 60 mg/m², intravenous infusion over at least 90 minutes, on day 1; Leucovorin: 400 mg/m², intravenous infusion over 2 hours, on day 1; 5-FU: 400 mg/m², intravenous bolus; 5-FU: 2400 mg/m², continuous infusion over 46-48 hours, on day 1; Bevacizumab: 5 mg/kg, intravenous infusion, on day 1. Repeat every 2 weeks.
Study: NCT06604403

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: After the hemodialysis, the patients will receive a 15-20 minute hand and foot massage. This application will be applied to the patients in two weekly dialysis sessions for a total of 8 sessions for four weeks. Before starting the massage applications, the patient's hands and feet will be washed and dried thoroughly. The patients will be given a semi-sitting or lying position that they can feel comfortable in. Before starting the hand and foot massage, the researcher will gently rub and warm their hands and wrists. The massages will start with a hand massage. A foot massage will be performed after the hand massage. 3-5 drops of baby oil applied at room temperature will be used to reduce friction during the massage. Effleurage, petrissage and friction styles of the massage will be applied.
Study: NCT06259916

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Participants in this condition will receive the standard alcohol dose

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Participants in this condition will receive the standard alcohol dose

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cannabis
Description: Participants in this group will self-administer legal-market flower cannabis

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cannabis
Description: Participants in this group will self-administer legal-market flower cannabis
Study: NCT04949490

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BNT162b2s01
Description: intramuscular (IM) injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BNT162b2
Description: IM injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BNT162b2
Description: IM injection

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BNT162b2
Description: IM injection
Study: NCT06599424

Intervention type: OTHER
Intervention: Observational
Description: Observational

Intervention type: OTHER
Intervention: Observational
Description: Observational
Study: NCT06589570

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Removable Partial Denture
Description: A removable partial denture (RPD) is a dental prosthesis designed to replace one or more missing teeth in the mouth. Unlike full dentures, which are used when all teeth are missing, an RPD is specifically made for patients who still have some of their natural teeth remaining. It restores both function and aesthetics, allowing patients to chew, speak, and smile with greater confidence.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Removable Partial Denture
Description: A removable partial denture (RPD) is a dental prosthesis designed to replace one or more missing teeth in the mouth. Unlike full dentures, which are used when all teeth are missing, an RPD is specifically made for patients who still have some of their natural teeth remaining. It restores both function and aesthetics, allowing patients to chew, speak, and smile with greater confidence.
Study: NCT06592027

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PRECEDEX INJ★ 2ML
Description: this group will receive single dose of dexmedetomidine 0.5 mcg /kg in 50 ml normal saline over 10 min IV infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PRECEDEX INJ★ 2ML
Description: single dose of dexmedetomidine 1 mcg /kg in 50 ml normal saline over 10 min IV infusion
Study: NCT04931563

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Anifrolumab
Description: Intravenous infusion (IV)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Intravenous infusion (IV)
Study: NCT05755516

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Self-expanding Intracranial Stent (Tonbridge)
Description: Stent assisted coiling with Self-expanding Intracranial Stent (Tonbridge).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LVIS and LVIS Jr. (MicroVention)
Description: Stent assisted coiling with LVIS and LVIS Jr. (MicroVention).
Study: NCT06470711

Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study: NCT05758194

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standardized RV Management
Description: Standardized parameters for post-operative management (i.e., Rhythm Management, Ventilation Management, RV Ischemia Management, RV Preload, RV Afterload, RV Contractility, and RV Geometry)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care RV Management
Description: No standardized parameters for post-operative management (i.e., Rhythm Management, Ventilation Management, RV Ischemia Management, RV Preload, RV Afterload, RV Contractility, and RV Geometry)
Study: NCT06004739

Intervention type: DRUG
Group type: OTHER
Intervention: Start Antibiotics / Continue Antibiotics for treatment of bacteriuria
Description: Participants will be randomized to start or continue with antibiotics (with antibiotic duration determined by the Most Responsible Physician \[MRP\]). Antibiotics choice to be selected by the MRP.

Intervention type: OTHER
Group type: OTHER
Intervention: No Antibiotics for treatment of bacteriuria
Description: Participants will be randomized to no antibiotics
Study: NCT04806464

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell))
Description: Intratumoral injection only. The dosing date can be the Day 1 only or Days 1 through 5.
Study: NCT05979454

Intervention type: DIAGNOSTIC_TEST
Intervention: Krebs von den Lungen-6 (KL6)
Description: KL-6 concentration will be measured using Sandwich ELISA technique (SinoGene Clone Biotech, China).
Study: NCT05259020

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ID140009
Description: Combination Product: ID140009 Ezetibmibe 10mg/ Rosuvastatin Ca 20.8mg/ Amlodipine 10mg/ Valsartan 160mg

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: ID1803+ID1805
Description: (Amlodipine 10mg/Valsartan 160mg)+(Ezetibmibe 10mg/ Rosuvastatin Ca 20.8mg)
Study: NCT05764928

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLEX 404
Description: BLEX 404 Oral Liquid, PO, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLEX 404
Description: BLEX 404 Oral Liquid, PO, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLEX 404
Description: BLEX 404 Oral Liquid, PO, BID

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLEX 404
Description: BLEX 404 Oral Liquid, PO, BID
Study: NCT06086925

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Black Raspberry
Description: Each BRB contains 1 gram of black raspberry powder equal to roughly 6 black raspberries.
Study: NCT05560100

Intervention type: OTHER
Intervention: Nominal Group Technique - 2 to 3 hour virtual meeting
Description: Participants will be invited to a 2-3 online virtual online meeting with the goal of constructing and defining elements for producing a risk statement for dry needling that can be used for informed consent.

Intervention type: OTHER
Intervention: Nominal Group Technique - 2 to 3 hour virtual meeting
Description: Participants will be invited to a 2-3 online virtual online meeting with the goal of constructing and defining elements for producing a risk statement for dry needling that can be used for informed consent.
Study: NCT05433181

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACE2 Chewing Gum
Description: The IP is formulated as an oral plant powder, which is packaged into a chewing gum. No specific excipient, buffer, salt or pH is required. CTB-ACE2, with efficient binding to both GM1 and ACE2 receptors, effectively blocks binding of the spike protein and viral entry into human cells. Oral epithelial cells are enriched with both receptors. In addition, ACE2 directly binds to the spike protein and inactivates SARS-CoV-2 virus. Therefore, CTB-ACE2 chewing gum is being evaluated for impact on entry and transmission of SARS-CoV-2.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Chewing Gum
Description: Chewing gum containing wild-type lyophilized plant cells manufactured to match the IP.
Study: NCT05143983

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Positive valence music
Description: Subjects will have to listen to 3 minutes of unfamiliar musical excerpts, with positive valence characteristics (fast tempo, major key). They will be told to listen carefully in order to then answer a short questionnaire. The listening will be followed by an liking scale (from 1 : not liked at all, to 5 : liked a lot) and a familiarity scale (from 1 : not familiar at all, to 5 : very familiar).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Positive valence music
Description: Subjects will have to listen to 3 minutes of unfamiliar musical excerpts, with positive valence characteristics (fast tempo, major key). They will be told to listen carefully in order to then answer a short questionnaire. The listening will be followed by an liking scale (from 1 : not liked at all, to 5 : liked a lot) and a familiarity scale (from 1 : not familiar at all, to 5 : very familiar).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Neutral valence music
Description: Subjects will have to listen to 3 minutes of unfamiliar musical excepts with neutral valence. They will be told to listen carefully in order to then answer to a short questionnaire. The listening will be followed by a liking scale (from 1 : not liked at all, to 5 : liked a lot) and a familiarity scale (from 1 : not familiar at all, to 5 : very familiar).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Neutral valence music
Description: Subjects will have to listen to 3 minutes of unfamiliar musical excepts with neutral valence. They will be told to listen carefully in order to then answer to a short questionnaire. The listening will be followed by a liking scale (from 1 : not liked at all, to 5 : liked a lot) and a familiarity scale (from 1 : not familiar at all, to 5 : very familiar).
Study: NCT05302349

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core Exercise Group
Description: Core Exercise Group Procedure:~Weeks 1-4 (Five days a week)~1. Hotpack ultrasound, conventional TENS, stretching exercises and strengthening exercises for low back pain.~2. Core stabilization exercise :~   * Active pelvic floor exercise (supine position)~  * Bridge exercise (supine position)~  * Back Extension and Ball Back Extension exercises (prone position)~  * Abdominal and Oblique Crunch exercises (supin position)~  * Leg lift exercise (prone position)~  * Plank and Side Plank exercise~  * Superman exercise~Weeks 5-8 (Three days a week)~1. Stretching exercises and strengthening exercises for low back pain.~2. Core stabilization exercise :~   * The same exercises as for Weeks 1-4 will perform.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Therapy Group
Description: Routine Therapy Group Procedure:~Weeks 1-4 (Five days a week)~1. Hotpack ultrasound, conventional TENS, stretching exercises and strengthening exercises for low back pain.~Weeks 5-8 (Three days a week)~1.Stretching exercises and strengthening exercises for low back pain.
Study: NCT05955313

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone Hydrochloride
Description: treatment of vulvodynia

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Naltrexone Hydrochloride
Description: treatment of vulvodynia
Study: NCT05507931

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 1 Serving of broccoli sprouts
Description: Participants will take 1 serving of broccoli sprouts daily for 28 days. The sprouts will be provided by the study team along with instructions on how to prepare the steamed broccoli sprouts (i.e., steamed for 10 minutes). In addition to taking the sprouts, participants will be asked to complete food diaries and surveys, collect blood and stool samples, as well as having 2 in-person visits.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 3 Servings of broccoli sprouts
Description: Participants will take 3 servings of broccoli a day for 28 days. The sprouts will be provided by the study team along with instructions on how to prepare the steamed broccoli sprouts (i.e., steamed for 10 minutes). In addition to taking the sprouts, participants will be asked to complete food diaries and surveys, collect blood and stool samples, as well as having 2 in-person visits.
Study: NCT06486038

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MRI standard and qMRI
Description: Non-contrast cervical spine MRI including morphological and quantitative MRI sequences on a 3 Tesla scanner. MRI examination includes conventional and experimental sequences

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MEPs and SSEPs
Description: Neurophysiological examination by motor and somatosensorial evocked potential using transcranial magnetic stimulation and electrical stimulation to the peripheral nerve

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromotor assessment
Description: Upper and Lower limb assessment: Purdue Pegboard Test (PTT), Box and Block test (BBT), Nine Hole Peg Test (NHPT), gait analysis and 30 seconds sit to stand test (30CST)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior cervical discectomy and fusion
Description: If applicable: Anterior cervical discectomy and fusion surgery using PEEK or modern carbon fiber material
Study: NCT05709795

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Confluent areas
Description: Use of omnipolar technology to guide CTI ablation in sites with both low wave speed and high voltage. If not successful then ablation of low wave speed sites. If not successful then ablation of high voltage sites. If not successful then CTI line (gold standard)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wave Speed
Description: Use of omnipolar technology to guide CTI ablation in sites with low wave speed. If not successful then ablation of sites with both low wave speed and high voltage. If not successful then ablation of high voltage sites. If not successful then CTI line (gold standard)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Voltage
Description: Use of omnipolar technology to guide CTI ablation in sites with high voltage. If not successful then ablation of sites with both low wave speed and high voltage. If not successful then ablation of low wave speed sites. If not successful then CTI line (gold standard)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CTI line
Description: Do not use omnipolar information. CTI line performance
Study: NCT04900987

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Steri-strips
Description: Pneumatic TR band compression with use of steri-strips
Study: NCT05469984

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ampicillin Only Product
Description: women will be randomize to receive Ampicillin Only Product or ampicillin plus gentamicin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ampicillin Only Product
Description: women will be randomize to receive Ampicillin Only Product or ampicillin plus gentamicin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ampicillin plus gentamicin
Description: women will be randomize to receive Ampicillin Only Product or ampicillin plus gentamicin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ampicillin plus gentamicin
Description: women will be randomize to receive Ampicillin Only Product or ampicillin plus gentamicin
Study: NCT04268004

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: FP Decision Tool and Discussion
Description: The intervention will be administered by a trained interventionist. The interventionist will administer the digital FP Decision Tool to families in the intervention arm. The tool asks questions examining each AYA's thoughts or feelings regarding parenthood and fertility preservation. The parent version asks the same questions, plus additional questions asking the parent to rate their son's feelings on certain topics (i.e., whether their son wants to have a child, whether their son would be as happy with an adopted child versus a biological child). Items are coded based on the domains of the Health Belief Model (perceived benefits, perceived barriers, perceived threats, self-efficacy, and cues to action). Items are scored and the trained interventionist will facilitate a guided discussion based on the family's responses and discrepancies.
Study: NCT05488574

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep breathing with Yoga positioning
Description: Deep breathing with yoga positioning 10min in morning, 1 minute noon, and 1 minute evening (diner)
Study: NCT05482997

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whey Protein Concentrate
Description: whey-based protein powder 32g powder mixed with 8-12 oz water

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whey Protein Concentrate
Description: whey-based protein powder 32g powder mixed with 8-12 oz water

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pea Protein Isolate, Rice Protein Concentrate, Hemp Protein
Description: plant-based protein powder. 32g powder mixed with 8-12 oz water

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pea Protein Isolate, Rice Protein Concentrate, Hemp Protein
Description: plant-based protein powder. 32g powder mixed with 8-12 oz water
Study: NCT05368051

Intervention type: COMBINATION_PRODUCT
Intervention: long course radiotherapy + capecitabine + PD-1 monoclonal antibody
Description: long course radiotherapy + capecitabine + PD-1 monoclonal antibody treatment combinations in patients with locally advanced rectal cancer
Study: NCT05694572

Intervention type: DEVICE
Intervention: Implantation of a CIED
Description: Implantation of a CIED

Intervention type: DEVICE
Intervention: Implantation of a CIED
Description: Implantation of a CIED

Intervention type: DEVICE
Intervention: Implantation of a CIED
Description: Implantation of a CIED
Study: NCT06324565

Intervention type: DIAGNOSTIC_TEST
Intervention: D-Dimer test
Description: All patients in whom preoperative diagnostics have not been able to exclude a surgical pathology and who are candidates for diagnostic-therapeutic surgery will be referred for minimally invasive abdominal exploration in the real suspicion of ovarian torsion. During the pre-operative phase, blood exams will be performed including coagulation which will be integrated with the D-dimer values. In addition, as usual, the clinical examination of the patients will be performed integrated with the various diagnostic image tools generally used in this category of patients (abdomen ultrasound +/- magnetic resonance in urgency).
Study: NCT05198908

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR group
Description: Women in this group will wear virtual reality glasses (15-20 minutes) until the episiotomy repair begins and ends. At the same time, the hospital protocol will be applied to this group.~Before episiotomy repair, each woman is given superficial perineal anesthesia with a 4 ml ampoule of Jetocaine (ADEKA®, lidocaine HCl 40 mg/2 mL, epinephrine 0.025 mg/2 mL). This dose is repeated if necessary.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Skin to skin group
Description: For women in this group, a warm sterile operating room towel will be placed on the newborn until the episiotomy repair begins and ends, so that her naked body remains on the mother's chest.At the same time, the hospital protocol will be applied to this group.~Before episiotomy repair, each woman is given superficial perineal anesthesia with a 4 ml ampoule of Jetocaine (ADEKA®, lidocaine HCl 40 mg/2 mL, epinephrine 0.025 mg/2 mL). This dose is repeated if necessary.
Study: NCT06328803

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation training
Description: Including 1) Basic treatment, including corresponding control of risk factors and education on healthy lifestyles. 2)Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation training
Description: Including 1) Basic treatment, including corresponding control of risk factors and education on healthy lifestyles. 2)Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Breathing Exercises
Description: Active breathing exercises aim to enhance the strength and flexibility of respiratory muscles through a series of exercises, improving breathing patterns and increasing respiratory efficiency. The following are common components of active breathing exercises: 1) Deep Breathing. 2) Chest Expansion. 3) Diaphragmatic Breathing. 4) Coughing Techniques. 5) Expiratory Resistance Training. 6) Gradual Increase in Activity.
Study: NCT05231031

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic exercise
Description: continuous aerobic exercise on a treadmill

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: continuous aerobic exercise on a treadmill

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: breathing exercise
Description: continuous aerobic exercise plus breathing exercise (Mindfulness)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Relaxation training
Description: continuous aerobic exercise plus relaxation training
Study: NCT05532982

Intervention type: OTHER
Intervention: Interviews and Surveys
Description: Qualitative interviews and surveys

Intervention type: OTHER
Intervention: Interviews and Surveys
Description: Qualitative interviews and surveys

Intervention type: OTHER
Intervention: Interviews and Surveys
Description: Qualitative interviews and surveys

Intervention type: OTHER
Intervention: Interviews and Surveys
Description: Qualitative interviews and surveys
Study: NCT05897450

Intervention type: OTHER
Intervention: Transversus abdominis plane (TAP) block
Description: Transversus abdominis plane (TAP) block: injection of a local anesthetic into a region between the internal oblique and transversus abdominis muscles.