TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04521647

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Participants will receive two nicotine concentrations via e-cigarettes. Each exposure will be 10 3-sec puffs and ad libitum use

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine
Description: Participants will receive two nicotine concentrations via e-cigarettes. Each exposure will be 10 3-sec puffs and ad libitum use
Study: NCT06452355

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KOKO Device
Description: The intrauterine rolling drain is extended into the uterus, where low pressure vacuum is applied to the uterus through the fabric intrauterine rolling drain. The KOKO™ device utilizes this vacuum to remove excess blood and compress the uterus reducing further blood loss.
Study: NCT06093893

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: 1 mcg/kg will be administered intravenously over 10 minutes; followed by maintenance infusion of 0.2 to 1 mcg/kg/hour.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicardipine
Description: 1 mg will be administered intravenously and increase by 0.5-1 mg if the initial dose is ineffective, to a maximum of 15 mg / hour or

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Labetalol
Description: 20 - 80 mg will be administered intravenously at 10-minute intervals to maximum of 300 mg;
Study: NCT06309641

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample after treatment
Description: Blood samples for measurement of methemoglobin are obtained directly before and 30-120 minutes after drug administration.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample after treatment
Description: Blood samples for measurement of methemoglobin are obtained directly before and 30-120 minutes after drug administration.

Intervention type: OTHER
Intervention: Case reports
Description: Description of clinical course and methemoglobin levels in patients with severe anemia who developed methemoglobinemia after intravenous administration of ferric derisomaltose.
Study: NCT06165497

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.
Study: NCT05684068

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Gum Graft Placed on Split Thickness Periosteal Bed Preparation
Description: The provider will administer local anesthesia into the subject's gum in order to numb both the subject's donor and recipient areas for gum grafts. Next, the provider will use a surgical blade to dissect the gum graft from the subject's donor site. At the subject's recipient gum recession defect site, the provider will dissect some of the tissue at the subject's recipient site but still keep a small layer of tissue at the subject's recipient site before placing a gum graft from the donor site. Afterward, the provider will place sutures in the subject's recipient site in order to promote healing/re-growth.
Study: NCT05586204

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Link to a broad set of vaccine venues
Description: The reminder will encourage people to claim their dose today by booking an appointment. It will contain a link to schedule a booster appointment at UCLA Health and a link to vaccine.gov (where people can find a wide set of local pharmacies that carry the bivalent booster).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Link to a broad set of vaccine venues
Description: The reminder will encourage people to claim their dose today by booking an appointment. It will contain a link to schedule a booster appointment at UCLA Health and a link to vaccine.gov (where people can find a wide set of local pharmacies that carry the bivalent booster).
Study: NCT04957394

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Partner
Description: The Family Partner intervention is based on well-known elements for preventing child abuse and neglect, such as 1) high intensity intervention with home visitations, 2) coordination of services, 3) an ecological perspective, 4) parental guidance, and 5) an emphasis on a therapeutic relationship with parents to create trust, change and agency.~Family Partners must have relevant professional background and education, such as social work, child welfare services and other health/welfare occupations. They must have a personal attitude for relation-based service delivery in a home-setting, a long work experience and in-depth knowledge of municipal welfare services.~Each practitioner will follow five families. The estimated duration of the intervention is 12 months, but might go over longer stretches of time if it is considered beneficial for the families. The minimum duration of the intervention is 3 months.
Study: NCT06165497

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.
Study: NCT06432335

Intervention type: OTHER
Group type: OTHER
Intervention: E-Socket Monitoring
Description: Limb-socket motion data is collected during participant take-home use. Bimonthly telephone interviews are conducted to assess participant residual limb health status. Analysis is conducted to determine if limb motions and activity changes precede limb health changes.
Study: NCT05637788

Intervention type: DIAGNOSTIC_TEST
Intervention: CT Scan Radiomics Features Extraction
Description: Extraction of CT radiomics data through AI
Study: NCT05502354

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: removal of transanal drainage tube
Description: removal of transanal drainage tube after laparoscopic anterior resection for rectal carcinoma according to postoperative CRP trajectory
Study: NCT06010784

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family support
Description: * Family tip sheets sent via mobile text at the start of the program and then every 3 weeks, to a total of 6 mobile text messages~* Weeks 1-4 (4 weeks):~  i. Welcome package mailed in the first week of the program ii. Weekly: one 10-lbs box of produce iii. Recipes accompanying each box (sample recipe card attached to submission) iv. Bi-Weekly: Grocery store gift cards (2x USD 20, to a total of USD 40)~* Weeks 5-19 (total of 10 weeks over the 19-week study timeline):~  i. An optional online form (goal sheet) is sent to the parent/caregiver every other week (total 5) with questions about trying new FV items to be submitted in the next 7 days. As an incentive, a USD 10 gift card is sent to those who complete it (a potential total of USD 50).~ii. Week 11: an extra USD 20 gift card in the week after a school holiday to re-engage participants due to the school-year break.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: BGCAA's after-school program with CATCH curriculum
Description: 1. The whole BGCAA's after-school program runs for 3h, Mon-Fri for the school year across all sites where the organization offers the program. All children enrolled are expected to attend a minimum of 2x/week.~2. In the BGCAA's after-school program, children participate in active recreational time (approx. 60 min, offered 1x/week at a minimum) which is a mixture of free play, structured physical activity games, and/or sports activities (including soccer, football, and basketball).~3. Uniquely to sites participating in the study, BGCAA's staff will deliver selected CATCH (Coordinated Approach to Child Health) curriculum components in blocks of 45-60 min, 2x/week, as part of the after-school program. The curriculum will focus on healthy eating education and physical activity designed for elementary school-aged children. More information on CATCH at https://catch.org/ (accessed 8/11/2023)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BGCAA's after-school program with CATCH curriculum
Description: 1. The whole BGCAA's after-school program runs for 3h, Mon-Fri for the school year across all sites where the organization offers the program. All children enrolled are expected to attend a minimum of 2x/week.~2. In the BGCAA's after-school program, children participate in active recreational time (approx. 60 min, offered 1x/week at a minimum) which is a mixture of free play, structured physical activity games, and/or sports activities (including soccer, football, and basketball).~3. Uniquely to sites participating in the study, BGCAA's staff will deliver selected CATCH (Coordinated Approach to Child Health) curriculum components in blocks of 45-60 min, 2x/week, as part of the after-school program. The curriculum will focus on healthy eating education and physical activity designed for elementary school-aged children. More information on CATCH at https://catch.org/ (accessed 8/11/2023)
Study: NCT05164627

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: patients will receive Dexmedetomidine infusion (0.2 mcg/kg/hr) from the start of the surgery till the end of it.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium Sulphate
Description: patients will receive Magnesium infusion (10 mg/kg/hr) from the start of the surgery till the end of it.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: After patient arrival at the PACU, Paediatric Anaesthesia Emergence Delirium (PAED) scale ,Ramsay sedation scores (RSS), emergence agitation, HR, and mean arterial blood pressure (MAP) were recorded every 5 min during the first 30 min, then every 10 min for the remaining 30 min of the recovery room stay. Patients were then transferred to the ward. All postoperative observations and scores were performed by the same anesthesiologist who was blinded to the group assignment
Study: NCT05260827

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heated tobacco product
Description: Sham heated tobacco product

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heated tobacco product
Description: Sham heated tobacco product
Study: NCT04996251

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine Injection
Description: 0.25% Bupivacaine being used as local anesthetic to inject into incision sites of tracer sites during a laparoscopic/robotic-assisted sacrocolpopexy
Study: NCT06165497

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meditation practices
Description: Participants will listen to recordings of short meditation practices drawn from the Healthy Minds Program.

Intervention type: OTHER
Group type: OTHER
Intervention: Internet-as-usual
Description: Participants will be instructed to use the internet as they typically do.

Intervention type: OTHER
Group type: OTHER
Intervention: Internet-as-usual
Description: Participants will be instructed to use the internet as they typically do.
Study: NCT05586204

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Doctors' recommendation and value of vaccine
Description: The reminder will contain information about the value of the bivalent booster and doctors' recommendation to get it

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Doctors' recommendation and value of vaccine
Description: The reminder will contain information about the value of the bivalent booster and doctors' recommendation to get it

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Doctors' recommendation and value of vaccine
Description: The reminder will contain information about the value of the bivalent booster and doctors' recommendation to get it
Study: NCT06097416

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neoadjuvant Chemoradiotherapy
Description: 5-FU is a fluoropyrimidine antimetabolite considered to act primarily as an inhibitor of thymidylate synthase. 5-FU is supplied as a colourless-to-faint yellow solution in 10-mL single use vials. Each 10 mL of solution contains 500 mg 5-FU, with pH adjusted to approximately 9.2 with sodium hydroxide.~The CRT regimen consists of the standard algorithms: a total of 5400-5600 cGy of radiation (4500 cGy to the pelvis, with an integrated boost to the primary tumour and involved nodes of 500 cGy followed by an option boost to the primary tumour and involved nodes) delivered in 27-28 fractions, respectively, of 180-200 cGy each over a 5-6 week period.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Total Neoadjuvant Therapy
Description: 5-FU is a fluoropyrimidine antimetabolite considered to act primarily as an inhibitor of thymidylate synthase. 5-FU is supplied as a colourless-to-faint yellow solution in 10-mL single use vials. Each 10 mL of solution contains 500 mg 5-FU, with pH adjusted to approximately 9.2 with sodium hydroxide.~Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2- diaminocyclohexane with an oxalate ligand as a leaving group. Platinum content is 48.1% to 50.1%.~All patients received the same chemotherapy (FOLFOX) and long-course chemoradiotherapy (50.4 Gy in 28 fractions) before surgery.
Study: NCT05834244

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Given by IV (vein)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Given by IV (vein)
Study: NCT04999800

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab (formerly lambrolizumab, brand name Keytruda) is a humanized antibody used in cancer immunotherapy. This includes to treat melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, an stomach cancer

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anlotinib
Description: Anlotinib is an oral small molecule multi-target receptor tyrosine kinase inhibitor
Study: NCT05670678

Intervention type: DIETARY_SUPPLEMENT
Intervention: a2 growing up stage 3 formula puls lactoferrin supplement
Description: The participants in this group will consume 4-5 scoops (8.5g/scoop) of the assigned formula each time, and 4 times per day

Intervention type: DIETARY_SUPPLEMENT
Intervention: Enfinitas growing up stage 3 formula
Description: The participants in this group will consume 4 scoops (10g/scoop) of the assigned formula each time, and 3 times per day
Study: NCT05390515

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tildrakizumab Prefilled Syringe
Description: IL-23 inhibitor
Study: NCT04566276

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChulaCov19 vaccine
Description: SARS-Cov2 Wild-type S-spike mRNA/ lipid nanoparticle (LNP) vaccine

Intervention type: OTHER
Group type: OTHER
Intervention: Placebo
Description: Saline
Study: NCT06121739

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Child Mental Health Literacy Program
Description: The workshop has a participant-oriented character, seeking to apply the more theoretical contents to the local school context. It has four units and a total of nine modules, each lasting 90 or 120 minutes, with reference material on an educational platform. The topics are : 1) the person behind the role of educator; 2) the school community and its influence on the healthy development of students; 3) the expected development and its alterations in the different evolutionary stages; 4) common and differential factors of child and adolescent mental health disorders; 5) Stigma in Mental Health; 6) screening, the first care, and use of devices for the prevention and treatment of mental health disorders in children and adolescents.
Study: NCT04910204

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FES Therapy combined with task-specific training (FEST+TST)
Description: The FEST+TST protocol consists of a 1-hour session, 3 to 5 days a week, for up to 12 weeks (40 sessions total) in addition to conventional occupational and physical therapies according to the standard of care.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FES Therapy combined with task-specific training (FEST+TST)
Description: The FEST+TST protocol consists of a 1-hour session, 3 to 5 days a week, for up to 12 weeks (40 sessions total) in addition to conventional occupational and physical therapies according to the standard of care.
Study: NCT05834244

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NK Cells
Description: Given by IV (vein)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NK Cells
Description: Given by IV (vein)
Study: NCT05809466

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vegan diet
Description: A self-composed 12 week fully plant-based diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vegan diet
Description: A self-composed 12 week fully plant-based diet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance exercise
Description: Biweekly resistance exercise for 12 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Omnivorous diet
Description: Habitual diet containing both animal- and plant-based food products
Study: NCT05214521

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: digital interactive technology Smart glove SensoRehab
Description: Participants will receive rehabilitation program including sessions on the Smart glove SensoRehab (SGSR) system. The program for IS patients includes 10 sessions with the SGSR: 15-30 minutes once a day for the affected hand, 2 weeks.
Study: NCT06378281

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified teach-to-goal informed consent
Description: Enhanced procedure to improve informed consent in vulnerable populations.
Study: NCT06215326

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: moderate-intensity continuous training
Description: Participants in MICT group will need to additional complete a total of 12 supervised training sessions in 2-3 weeks.After a warm-up of 5 minutes at 50% at peak WR, the patient start exercising at 60%-70% peak WR for 30-40 minutes (four 5-8 minutes sets, with a 2-min rest in between), and then the patients cooled down for 5 minutes at 50% peak WR. Moderate-intensity exercise training intensity control at 55-74% HRmax or 40-69% VO2peak or PRE12-13 as recommended by guidelines.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: high-intensity interval training
Description: Participants in HIIT group will need to additional complete a total of 12 supervised training sessions in 2-3 weeks.After a 5-minute warm-up at 50% at peak WR, the patients complete 20 series of vigorous-intensity sprint (80%-100% peak WR for 30-60s) separated by a low-intensity recovery (30% peak WR or completely rest for 15s), and then the patients cooled down for 5 minutes at 50% peak WR. Participants will begin training at a relatively moderate intensity (60%-65% peak WR) for the first 3 sessions and gradually increase to the target intensity beginning on the 4th session. Intensity control of high-intensity exercise training at 75-90% HRmax or 70-85% VO2peak or PRE14-16 as recommended by guidelines.
Study: NCT06201949

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Articaine infiltration technique
Description: infiltration will be performed with articaine and epinephrine 1/100 000 (Artinibsa, Inibsa, Barcelona, Spain) for all patients on their second pri-mary molar. The needle tip was placed in the buccal vestibule and then directed to the apex of the tooth and about one-third to one-fourth of the cartridge will be slowly discharged

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Articaine nerve block technique
Description: this technique will be performed with articaine and epinephrine 1/100 000 for all patients on their second primary molar with conventional technique inferior alveolar nerve block. The thumb will be placed on the occlusal surface of intended side and protruded toward the inner oblique ridge of ramus and then placed in touch with retromolar pad. The syringe will be directed between the two mandibular primary molars of opposite side and the needle will be pushed forward until hitting the bone, then the injection will be slowly done. After three to five minutes, treatment will be started, after numbness in the lower lip is achieved
Study: NCT05283421

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Estrogen
Description: Women will receive active estrogen treatment or placebo prior to the colposcopic examination

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Women will receive active estrogen treatment or placebo prior to the colposcopic examination