TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06210282

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Focused lung ultrasound (FLUS)
Description: We will use a 14-zone scanning approach. Each hemithorax is divided into anterior, lateral, and posterior surfaces. The anterior and lateral surfaces on each hemithorax are divided into an upper and lower quadrant. The posterior surfaces on each hemithorax are divided into an upper, middle, and lower quadrant. Each quadrant represents a scanning zone. Each scanning zone should be assessed using FLUS. The participating general practitioners use point-of-care ultrasound on a weekly basis before trial commencement and will use the ultrasonography device already available to them.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants assigned to the control group will receive the GP's usual care of adults (≥ 18 years) presenting with symptoms of an acute LRTI where the GP suspects CAP. Usual care will be used as a pragmatic comparator to reflect the current standard examinations and care of these patients in general practices in Denmark. Usual care is recommended to follow applicable guidelines from the Danish Society of General Practitioners (DSAM) and Lægehåndbogen \[The Doctor's Handbook\].

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Participants assigned to the control group will receive the GP's usual care of adults (≥ 18 years) presenting with symptoms of an acute LRTI where the GP suspects CAP. Usual care will be used as a pragmatic comparator to reflect the current standard examinations and care of these patients in general practices in Denmark. Usual care is recommended to follow applicable guidelines from the Danish Society of General Practitioners (DSAM) and Lægehåndbogen \[The Doctor's Handbook\].
Study: NCT05540106

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nature Coloring Packet
Description: Coloring packet containing nature scenes

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Geometric Shape Coloring Packet
Description: Coloring packet containing geometric shapes
Study: NCT05370989

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Technology-Based Parent School Program
Description: The program will be continued for 10 weeks in the intervention group and will be included five web-based modules, five online group interactions after each module, and consultation throughout the program and the follow-up period.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ongoing treatment
Description: Health service of the control group will ongoing.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ongoing treatment
Description: Health service of the control group will ongoing.
Study: NCT05540106

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Activity Book
Description: Pages containing word searches, connect the dots, etc.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Blank Paper and Pencil
Description: Blank sheets of paper and a pencil.
Study: NCT05948930

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Progressive aerobic exercise
Description: Progressive aerobic exercise
Study: NCT05488379

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group well child care
Description: Beginning with the 1-month well child care visit, mother-infant dyads will participate in well child care together, with subsequent visits occurring at the American Academy of Pediatrics recommended intervals (2, 4, 6, 9, 12, 15, and 18 months of age).
Study: NCT05948930

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adaptive cognitive training
Description: Adaptive cognitive training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Combined
Description: Combine adaptive cognitive and progressive aerobic exercise training
Study: NCT05316129

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follicle Stimulating Hormone Receptor T Cells
Description: Participants will receive an infusion of autologous t cells genetically modified ex vivo to express the FSHR-specific 4-1BB/CD3ζ CER.
Study: NCT04715724

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Positioning and Attachment video-based simulation (telesimulation)
Description: Participants will teach a standardized patient actor (SP) to position and attach the baby doll at the breast of the Lactation Simulation Model in a video-based simulation (telesimulation)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Positioning and Attachment video-based simulation (telesimulation)
Description: Participants will teach a standardized patient actor (SP) to position and attach the baby doll at the breast of the Lactation Simulation Model in a video-based simulation (telesimulation)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Positioning and Attachment video-based simulation (telesimulation)
Description: Participants will teach a standardized patient actor (SP) to position and attach the baby doll at the breast of the Lactation Simulation Model in a video-based simulation (telesimulation)
Study: NCT05140993

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: extended emotional and orientation support
Description: extended emotional and orientation support
Study: NCT02145910

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vemurafenib
Description: Given PO
Study: NCT04946825

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy patch
Description: The nicotine patch is attached to the participant's skin and provides a slight constant stream of nicotine. The smaller dose is meant to reduce nicotine dependence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy patch
Description: The nicotine patch is attached to the participant's skin and provides a slight constant stream of nicotine. The smaller dose is meant to reduce nicotine dependence.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy lozenge
Description: The nicotine lozenge contains small amounts of nicotine, which a participant slowly dissolves in their mouth. Like the patch, the smaller dose is meant to reduce nicotine dependence.
Study: NCT02145910

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vemurafenib
Description: Given PO

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Whole-brain radiation therapy (WBRT)
Description: Undergo WBRT

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiosurgery (SRS)
Description: Undergo SRS
Study: NCT06058780

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implantable Collamer Lens (ICL)
Description: Phakic intraocular lenses (pIOL) have proven to be a great alternative to corneal refractive surgery in certain situations. They offer several advantages over corneal techniques, such as being suitable for high myopes and causing relatively fewer higher-order aberrations

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implantable Intraocular Lens (IPCL)
Description: The IPCL offers a distinct economic advantage as the cost of the IPCL implant is only 2. times that of the ICL implant. Moreover, the IPCL can correct higher degrees of myopia, up to -30. D, compared to the maximum correction of -18. D provided by the ICL.
Study: NCT06349486

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: vonoprazan, amoxicillin, tripotassium dicitrate bismuthate
Description: bismuth-amoxicillin-vonoprazan triple therapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: vonoprazan, amoxicillin
Description: vonoprazan-amoxicillin dual therapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: rabeprazole, amoxicillin, clarithromycin
Description: proton pump inhibitor-based standard triple therapy
Study: NCT05915130

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gait training
Description: They will negotiate (natural or virtual) obstacles such as avoiding a rock or crossing over a tree root, thus improving their gait adaptability capacities.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gait training
Description: They will negotiate (natural or virtual) obstacles such as avoiding a rock or crossing over a tree root, thus improving their gait adaptability capacities.
Study: NCT04590144

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: INVICTA lead
Description: The implant or the attempt to implant an INVICTA lead
Study: NCT05415956

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Walking exercise therapy
Description: Moderate-to-high intensity walking exercise therapy (7 weeks, 14 session) with progression in duration and intensity.
Study: NCT04946825

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy lozenge
Description: The nicotine lozenge contains small amounts of nicotine, which a participant slowly dissolves in their mouth. Like the patch, the smaller dose is meant to reduce nicotine dependence.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Quit electronic cigarettes
Description: Participants will receive instruction and text message support to quit electronic cigarettes when they quit combustible cigarettes.
Study: NCT05228249

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autologous Hematopoietic Stem Cell Transplantation
Description: Undergo peripheral blood ASCT

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carmustine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Loncastuximab Tesirine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melphalan
Description: Given IV
Study: NCT06502951

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling,Thrust Manipulation
Description: HVLA thrust manipulation to upper cervical and upper thoracic regions. Dry needling to cervicothoracic and craniofacial regions. Up to 8 treatment sessions over 4 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise,Non-thrust Mobilization
Description: Non-thrust mobilization and exercise to upper cervical and upper thoracic regions. Up to 8 treatment sessions over 4 weeks.
Study: NCT05522634

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TJAOA101
Description: Once enrolled, participants will be administrated TJAOA101
Study: NCT05530850

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Holistic Corrective Exercise Program
Description: A holistic approach corrective exercise program including corrective exercises and postural perception training,

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thoracic exercise program
Description: Thoracic region focused exercise program
Study: NCT04946825

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Quit electronic cigarettes
Description: Participants will receive instruction and text message support to quit electronic cigarettes when they quit combustible cigarettes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Continue electronic cigarettes
Description: Participants will receive instruction and text message support to continue using electronic cigarettes after they quit combustible cigarettes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Continue electronic cigarettes
Description: Participants will receive instruction and text message support to continue using electronic cigarettes after they quit combustible cigarettes.
Study: NCT05529069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirtobrutinib
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given by PO
Study: NCT04730167

Intervention type: OTHER
Intervention: Neurological and neuropsychological assessments / MRI / PET scan / Video-oculography.
Description: Essential data for this study are those collected during the concussion assessment, carried out as part of routine care at Princess Grace Hospital (medical background; history of sports practice and history of concussions; data extracted from clinical and neuropsychological evaluations, from imaging exams (MRI and PET-Scan) and from eye-tracking evaluation).
Study: NCT05177081

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Preemptive management using home BIA monitoring system
Description: Patients check their body composition and fluid using Home BIA system. Investigators analyze patients' body congestion status and send patient's edema status and direction of extra-diuretics usage to enrolled patients every one week.
Study: NCT06175390

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI-46 PET/CT
Description: Tumor assessments by 18F-FDG PET/CT (per PERCIST v1.0) and 68Ga-FAPI-46 PET/CT will be performed at: baseline and after the first 2 treatment cycles (between C2D15 and C3D1).

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI-46 PET/CT
Description: Tumor assessments by 18F-FDG PET/CT (per PERCIST v1.0) and 68Ga-FAPI-46 PET/CT will be performed at: baseline and after the first 2 treatment cycles (between C2D15 and C3D1).

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tumor samples analysis
Description: Patients will undergo a mandatory biopsy of the primary tumor at baseline, after the first 2 treatment cycles and during the surgery. A lymph node biopsy will be performed at baseline if feasible in cohort A, and and in case of disease progression for cohort B (if clinically feasible).~In addition to the usual morphological and immunohistochemical (ER, PR, HER2+, CPS score, PD-L1 status with SP142 ...) analyses in the cohort A and cohort B , exploratory analyses will be performed.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tumor samples analysis
Description: Patients will undergo a mandatory biopsy of the primary tumor at baseline, after the first 2 treatment cycles and during the surgery. A lymph node biopsy will be performed at baseline if feasible in cohort A, and and in case of disease progression for cohort B (if clinically feasible).~In addition to the usual morphological and immunohistochemical (ER, PR, HER2+, CPS score, PD-L1 status with SP142 ...) analyses in the cohort A and cohort B , exploratory analyses will be performed.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood samples analysis: Circulating Tumor DNA
Description: Blood samples will be collected at baseline. In addition for cohort A at cycles 2 and 3, within 21 days before surgery, 10 to 21 days after surgery and at cycle 8 after surgery. In addition for cohort B after the first 2 treatment cycles and in case of disease progression (if clinically feasible).

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood samples analysis: Circulating Tumor DNA
Description: Blood samples will be collected at baseline. In addition for cohort A at cycles 2 and 3, within 21 days before surgery, 10 to 21 days after surgery and at cycle 8 after surgery. In addition for cohort B after the first 2 treatment cycles and in case of disease progression (if clinically feasible).
Study: NCT06415734

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: rTMS
Description: LF-rTMS of M1 contralateral to the brain lesion for 20 min, 1200 pulses, 120% RMT, treatment cycle of 5 days
Study: NCT04738851

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapy Mirror task
Description: The protocol has 3 conditions:~* A virtual TM task (TMV~* A classic TM task (TMC)~* A control task (TC)~The order of the 3 conditions will then be randomized to avoid potential biases linked to the sequence of conditions.
Study: NCT06135493

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan
Description: Using losartan to prevent paclitaxel-induced peripheral neuropathy
Study: NCT06329804

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isometric Handgrip Exercise Training (IHGT)
Description: Each IHGT session will consist of 4 x 2-minute contractions at 30% maximal voluntary contraction, with 2-minutes of rest in between, performed with the dominant hand. Training will be performed using an electronic hand dynamometer (Camry EH101, Zhongshan Camry Electronic Co. Ltd, Guangdong).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Isometric Handgrip Exercise Training (IHGT)
Description: Each IHGT session will consist of 4 x 2-minute contractions at 30% maximal voluntary contraction, with 2-minutes of rest in between, performed with the dominant hand. Training will be performed using an electronic hand dynamometer (Camry EH101, Zhongshan Camry Electronic Co. Ltd, Guangdong).
Study: NCT05406986

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: care bundle application
Description: The patients in the experimental group will be given care according to the current care bundle for 14 days
Study: NCT06247592

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Greater occipital nerve block
Description: Pulse Radiofrequency application to the greater occipital nerve will be applicated after radiofrequency cannula placed near the greater occipital nerve location at 42 degree, for 240 seconds.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Greater occipital nerve pulse radiofrequency
Description: The greater occipital nerve will be blocked with 5 cc 2% prilocaine.
Study: NCT06404125

Intervention type: DIAGNOSTIC_TEST
Intervention: Range of Motion of Shoulde Joint
Description: Goniometric measurements will be made for both upper extremities. Flexion, extension, abduction, adduction, internal and external rotation angles of the shoulder complex will be evaluated in the measurement.

Intervention type: DIAGNOSTIC_TEST
Intervention: Range of Motion of Shoulde Joint
Description: Goniometric measurements will be made for both upper extremities. Flexion, extension, abduction, adduction, internal and external rotation angles of the shoulder complex will be evaluated in the measurement.

Intervention type: DIAGNOSTIC_TEST
Intervention: Hand Grip Test
Description: The purpose of this test is to test the maximum isometric contraction strength of the hand and forearm muscles. A hand grip dynamometer (Jamar) will be used for the test. While the patient is sitting in the chair, the elbows will be close to the body and at 90 degree flexion, the wrist will be in a neutral position. The patient will be asked to grasp the dynamometer and squeeze it as hard as she can, and the average of 3 measurements made with an interval of 10 seconds. The test will be repeated for both upper extremities separately.

Intervention type: DIAGNOSTIC_TEST
Intervention: Hand Grip Test
Description: The purpose of this test is to test the maximum isometric contraction strength of the hand and forearm muscles. A hand grip dynamometer (Jamar) will be used for the test. While the patient is sitting in the chair, the elbows will be close to the body and at 90 degree flexion, the wrist will be in a neutral position. The patient will be asked to grasp the dynamometer and squeeze it as hard as she can, and the average of 3 measurements made with an interval of 10 seconds. The test will be repeated for both upper extremities separately.

Intervention type: DIAGNOSTIC_TEST
Intervention: Numeric Rating Scale
Description: Shoulder pain, feeling of tension and heaviness on the affected arm will be evaluated separately by numerical scale.
Study: NCT05675306

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dynamic Temporal and Tactile Cueing Treatment
Description: DTTC is a dynamic, motor-based treatment approach designed for children with severe CAS. This approach is based on Integral Stimulation (Edeal \& Gildersleeve-Neumann, 2011; Maas \& Farinella, 2012; Maas et al., 2019; Strand \& Debertine, 2000; Strand \& Skinder, 1999), in which the clinician instructs the child to listen to me, watch me, and do what I do and systematically taxes and supports the speech motor system to facilitate system-wide change in speech output (Strand, 2020).