TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06338904

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem-solving-based psychological intervention
Description: The intervention will include training in the components of the problem-solving model and other behavioral and cognitive skills such as detecting warning signals, monitoring mood, relaxation techniques, self-reinforcement, strategies for acting in crisis situations, engaging in enjoyable activities, mindfulness meditation techniques, or strategies for reframing irrational thoughts. It will be developed from the problem-solving model (D'Zurilla and Nezu, 1982) and will reference the indicated prevention program for depression (Vázquez et al., 2015), which has shown efficacy in reducing depressive symptoms and preventing the onset of depression episodes (Otero et al., 2015; Vázquez et al., 2013), with results on symptomatology maintained at 8 years (López et al., 2020); and the indicated prevention intervention that demonstrated efficacy in reducing suicide risk (Xavier et al., 2019).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem-solving-based psychological intervention
Description: The intervention will include training in the components of the problem-solving model and other behavioral and cognitive skills such as detecting warning signals, monitoring mood, relaxation techniques, self-reinforcement, strategies for acting in crisis situations, engaging in enjoyable activities, mindfulness meditation techniques, or strategies for reframing irrational thoughts. It will be developed from the problem-solving model (D'Zurilla and Nezu, 1982) and will reference the indicated prevention program for depression (Vázquez et al., 2015), which has shown efficacy in reducing depressive symptoms and preventing the onset of depression episodes (Otero et al., 2015; Vázquez et al., 2013), with results on symptomatology maintained at 8 years (López et al., 2020); and the indicated prevention intervention that demonstrated efficacy in reducing suicide risk (Xavier et al., 2019).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem-solving-based psychological intervention
Description: The intervention will include training in the components of the problem-solving model and other behavioral and cognitive skills such as detecting warning signals, monitoring mood, relaxation techniques, self-reinforcement, strategies for acting in crisis situations, engaging in enjoyable activities, mindfulness meditation techniques, or strategies for reframing irrational thoughts. It will be developed from the problem-solving model (D'Zurilla and Nezu, 1982) and will reference the indicated prevention program for depression (Vázquez et al., 2015), which has shown efficacy in reducing depressive symptoms and preventing the onset of depression episodes (Otero et al., 2015; Vázquez et al., 2013), with results on symptomatology maintained at 8 years (López et al., 2020); and the indicated prevention intervention that demonstrated efficacy in reducing suicide risk (Xavier et al., 2019).
Study: NCT04755075

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib
Description: Subjects to receive Surufatinib 250 mg on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib
Description: Subjects to receive Surufatinib 250 mg on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib
Description: Subjects to receive Surufatinib 250 mg on Day 1
Study: NCT05503173

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MCBMAP
Description: MCBMAP integrates motivational interviewing (MI) and cognitive-behavioral skill training interventions for unhealthy drinking with cognitive-behavioral and self- management approaches for chronic pain. The intervention is delivered through internet-based videoconferencing and supplemented with web-based content to support the intervention. The initial treatment session provides a rationale for addressing alcohol and pain together in the context of HIV management, and initiates MI related to alcohol use. Participants receive 6 additional treatment sessions over the subsequent weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Brief Advice and Information
Description: Through videoconferencing an interventionist will provide participants psychoeducation about the effects of alcohol and pain on HIV symptoms, advice/recommendations to reduce alcohol use, and a list of local treatment resources for alcohol and chronic pain.
Study: NCT06367231

Intervention type: OTHER
Intervention: VibrantMinds
Description: We are exploring the potential of computer games to reveal insights into the cognitive abilities of older adults. We developed the VibrantMinds (https://vibrant-minds.org/vibrantminds2/start) platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. Our evaluation focused on the usability of these games, their appeal to users, and their effectiveness in enhancing cognitive functions. The next phase of our study aims to determine whether these games can offer meaningful data on the cognitive skills of older adults.
Study: NCT05898100

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Distraction
Description: The experimental group will receive the VR video game Dream designed specifically for this study. Pharmaceutical treatment during the procedure such as the use of injected local anesthesia will be used if the procedure requires. Children will be able to play for the entire duration of the dental procedure. Dream aims at reducing anxiety in children aged 6 to 17 years old by mean of immersive distraction. The VR headset offers children with the ability of viewing the game they are playing in real time while simultaneously obstructing the partial view they would normally have of the procedure. In the event of non-cooperation during the appointment, any re-take or re-scheduling appointments will be compiled by the resident dentist. One parent will be allowed in the room during the dental procedure and their presence will be recorded.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dental Clinic's Standard Treatment
Description: The control group will only receive a care-as-usual approach. This includes a television mounted on the wall showing cartoons and the use of pharmaceutical treatment during the procedure such as the use of injected local anesthesia. In the event of non-cooperation during the appointment, any re-take or re-scheduling appointments will be compiled by the resident dentist. One parent will be permitted to be present in the room during the procedure as part of the clinic's usual protocol and their presence will be recorded. Children allocated to the control group will be offered the possibility to try the VR game after the study period if they choose so.
Study: NCT04438161

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PERCCS: Personalized Education Regarding Clinical and Community Supports
Description: A brief follow-up to the screening provided to 50% of the consented families (randomly assigned) that links their specific familial risks to community interventions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: PERCCS: Personalized Education Regarding Clinical and Community Supports
Description: A brief follow-up to the screening provided to 50% of the consented families (randomly assigned) that links their specific familial risks to community interventions.
Study: NCT06092554

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: LactoLevure
Description: Patients will receive two capsules, twice daily for 30 days, one through the nasogastric tube and one spread on the oropharynx. The probiotic capsules look identical to the placebo capsules; the powder will be similar when opened. The capsule for nasogastric tube will be opened and suspended in 100 ml of tap water. The capsule for the oropharynx will be opened and suspended in sterile water based surgical lubricant. The administration must happen at least 30 minutes after oral antiseptic product usage (e.g. daily chlorhexidine oral care), which otherwise might neutralize the study supplement's action.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive two capsules, twice daily for 30 days, one through the nasogastric tube and one spread on the oropharynx. The placebo capsules contain a powdered glucose polymer that is unharmful for the patient and will be provided by the sponsor. The placebo capsules look identical to the probiotic capsules; the powder will be similar when opened. The capsule for nasogastric tube will be opened and suspended in 100 ml of tap water. The capsule for the oropharynx will be opened and suspended in sterile water based surgical lubricant. The administration must happen at least 30 minutes after oral antiseptic product usage (e.g. daily chlorhexidine oral care), which otherwise might neutralize the study supplement's action.
Study: NCT05688878

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Threshold electrical stimulation
Description: Threshold stimulation (EDS) is based on low-intensity (\<100 Hz) and long-duration current and is applied with superficial electrodes. Threshold stimulation provides a natural proprioception by depolarizing the sensory and motor nerves without causing any muscle contraction.This treatment will be applied for 4 weeks, 3 days a week, for 1 hour.
Study: NCT06181942

Intervention type: DEVICE
Intervention: SP
Description: English name: da Vinci SP Surgical System Model and specification: SP1098 Manufacturer: Intuitive Surgical, Inc.
Study: NCT06194513

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention 1: Twice a day for 1 week PIOMI
Description: Preterm babies will receive two sessions of treatment every day for a week, for a total of 14 sessions. Each session will be five minutes. The application is done at a time when the baby is peaceful and not very hungry. When the application is performed, the baby is positioned on his back and in a way that feels comfortable.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention 2: Once a day for 2 weeks PIOMI
Description: Preterm babies will receive a total of 14 sessions of treatment, one every day for two weeks. Each session will be five minutes. The application is done at a time when the baby is peaceful and not very hungry. When the application is performed, the baby is positioned on his back and in a way that feels comfortable.
Study: NCT04756505

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bintrafusp Alfa
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Immunocytokine NHS-IL12
Description: Given SC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Undergo radiation therapy
Study: NCT04754360

Intervention type: OTHER
Intervention: Evaluation of functional impairment
Description: Symptom burden and functional impairment will be evaluated with EHRA Score, 6-min walk test and 30-second sit-to-stand test

Intervention type: OTHER
Intervention: Evaluation of pulmonary function
Description: Pulmonary function will be evaluated using basic spirometry and respiratory pressure meter.

Intervention type: OTHER
Intervention: Evaluation of quality of life
Description: Quality of life will be evaluated using Short Form-36 Questionnaire.

Intervention type: OTHER
Intervention: Evaluation of physical activity level
Description: Physical activity level will be evaluated using International Physical Activity Questionnaire Short Form
Study: NCT05352126

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Biocide
Description: The product being researched, which is a biocide solution in a spray for atmospheric use without a propellant, will be sprayed in the bedroom of each patient at a rate of 2 sprays per day in the evening (half an hour before going to bed).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biocide
Description: The product being researched, which is a biocide solution in a spray for atmospheric use without a propellant, will be sprayed in the bedroom of each patient at a rate of 2 sprays per day in the evening (half an hour before going to bed).
Study: NCT05123833

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hypospadias repair
Description: surgical repair of hypospadias

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hypospadias repair
Description: surgical repair of hypospadias
Study: NCT05653622

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Integrated boost technique (SIB) guided by PET FDOPA
Description: intensity-modulated irradiation scheme with integrated boost technique (SIB) guided by PET FDOPA during the chemo-radiotherapy
Study: NCT04973475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine Green
Description: Laparoscopic distal gastrectomy with lymph node dissection for early gastric cancer using Indocyanine Green Tracer
Study: NCT04808570

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ-B3525 tablets
Description: TQ-B3525 tablet administered 20mg orally, once daily in 28-day cycle.
Study: NCT06097000

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: powered exoskeletons
Description: Whether to use powered exoskeletons for exercise rehabilitation
Study: NCT06148688

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital Story
Description: Digital storytelling; It is used in education and training, business marketing, non-profit organizations such as libraries, community centers and museums, and health sciences education. Digital storytelling in health sciences can be a tool for patients and health science professionals to share their experiences, cope with diseases, and add a human element to health problems.~In the study, digital stories were created to increase the self-management of pregnant women with gestational diabetes. In creating a digital story; Qualitative studies involving the self-management experiences of women with gestational diabetes have been examined in the literature. Using the results of the studies, scenarios were created that included factors that facilitate and complicate diabetes self-management. The created scenarios were used in the digital storytelling initiative. A total of four long and four short digital story videos were prepared.
Study: NCT05813600

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirmatrelvir/Ritonavir
Description: Patients in both groups were given Lianhua Qingwen Capsule orally, 3 times/day, 6 g/time. oral antipyretic (ibuprofen suspension 10ml) and symptomatic supportive treatment for body temperature \>38.5 ℃. The study group was given Nirmatrelvir 300mg/Ritonavir 100mg orally, q12h, for 5 days, and the control group not given any antiviral drugs.
Study: NCT06538948

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: The intervention is not assigned to the participant after recruitment in the study, rather the intervention is an inclusion criteria for participation in the study.

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: The intervention is not assigned to the participant after recruitment in the study, rather the intervention is an inclusion criteria for participation in the study.

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: The intervention is not assigned to the participant after recruitment in the study, rather the intervention is an inclusion criteria for participation in the study.

Intervention type: PROCEDURE
Intervention: Bariatric Surgery
Description: The intervention is not assigned to the participant after recruitment in the study, rather the intervention is an inclusion criteria for participation in the study.
Study: NCT04896554

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health literacy scale
Description: The Turkish version of The European Health Literacy Survey (HLS-EU) Health Literacy Questionnaire scale (ASOY-TR) was used to measure health literacy. This scale consists of 47 questions. Each item has 4 degrees such that 1 = Very difficult, 2 = Difficult, 3 = Easy, 4 = Very easy. Code 5 is used for the expression I don't know. The total score that can be obtained from the scale is between 47-188. For the sake of ease of calculation, the total score is standardized with the following formula to take a value between 0-50.~Formula = Index = (arithmetic mean-1) x \[50/3\] High score means better health literacy.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health literacy scale
Description: The Turkish version of The European Health Literacy Survey (HLS-EU) Health Literacy Questionnaire scale (ASOY-TR) was used to measure health literacy. This scale consists of 47 questions. Each item has 4 degrees such that 1 = Very difficult, 2 = Difficult, 3 = Easy, 4 = Very easy. Code 5 is used for the expression I don't know. The total score that can be obtained from the scale is between 47-188. For the sake of ease of calculation, the total score is standardized with the following formula to take a value between 0-50.~Formula = Index = (arithmetic mean-1) x \[50/3\] High score means better health literacy.
Study: NCT03924752

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Powered hip exoskeleton
Description: The study team will test a powered hip exoskeleton and its capability to improve locomotion.
Study: NCT05949775

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Neoantigen mRNA Personalised Cancer vaccine
Description: Drug: Neoantigen mRNA Personalised Cancer vaccine in combination with Stintilimab Injection Subcutaneous Injection
Study: NCT06066827

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Minoxidil Topical
Description: 20 subjects received minoxidil only for the treatment of AGA

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Secretome from adipose-derived stem cells
Description: 20 subjects received the injection of secretome from adipose-derived stem cells only for the treatment of AGA

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Combination of minoxidil and secretome from adipose-derived stem cells
Description: 20 subjects received both minoxidil and injection of secretome from adipose-derived stem cells for the treatment of AGA
Study: NCT06494696

Intervention type: DIAGNOSTIC_TEST
Intervention: Ga-68 PSMA PET/MRI
Description: The participant will undergo a Ga-68 PSMA PET/MRI scan, and then be followed up for 2 years to see if prostate cancer is diagnosed.
Study: NCT06124625

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation combined to a digital maintenance program
Description: Individuals in this group undergo a 3-week inpatient rehabilitation program followed by a 12-week maintenance program (2 sessions per week à 90 minutes, digital and live). The multimodal programs consist of physiotherapy, training therapy, medical support, cognitive training, education and psychological support.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Rehabilitation without maintenance program
Description: Individuals in this group undergo a 3-week inpatient rehabilitation program followed by a 12-week usual care period.
Study: NCT05543577

Intervention type: OTHER
Intervention: Questionnaire
Description: Questionnaire

Intervention type: OTHER
Intervention: Questionnaire
Description: Questionnaire
Study: NCT05216679

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Night splints
Description: A night splint is a brace the patient wears on their foot to keep it in a dorsiflexed position while they sleep. It is the first line treatment for plantar fasciitis.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Triceps Surae Stretching and Flexibility Assessment Device (TESS)
Description: The TESS device is a slant board with a bar added for balance that the participant will stand on in 5 minute intervals throughout the day to stretch their calves, and potentially treat their plantar fasciitis symptoms.
Study: NCT04926051

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986172
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986172
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986172
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986172
Description: Specified dose on specified days

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Specified dose on specified days

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Specified dose on specified days

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Specified dose on specified days
Study: NCT04885803

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Softgel Vitamin D3
Description: 5000IU vitamin D3 taken as single oral softgel once daily for 30 days

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nano Liquid Vitamin D3
Description: 5000IU vitamin D3 taken as liquid oral spray once daily for 30 days

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 25(OH)D Blood Serum Test
Description: A sample of blood is drawn off and processed for 25(OH)D levels at baseline, after 15 days of supplementation, and after 30 days of supplementation

Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: 25(OH)D Blood Serum Test
Description: A sample of blood is drawn off and processed for 25(OH)D levels at baseline, after 15 days of supplementation, and after 30 days of supplementation

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: 25(OH)D Blood Serum Test
Description: A sample of blood is drawn off and processed for 25(OH)D levels at baseline, after 15 days of supplementation, and after 30 days of supplementation

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control
Description: Liquid oral spray once daily for 30 days. Solution identical in smell, taste, color, and production process to Nano Liquid D3, but containing no Vitamin D3.
Study: NCT04832958

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99m-TC-PSMA-I&S
Description: * 99mTc-PSMA-I\&S intravenous injection the day before surgery~* 99mTc-PSMA-I\&S SPECT/CT imaging~* 99mTc-PSMA-RGS to detect an increased count rate at the level of the nodal stations
Study: NCT06020586

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hair lotion
Description: ECOHAIR
Study: NCT05502042

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Case Manager and Peer Support Group
Description: Assignment of a Village health team member to provide support to the family through SMS messages (weeks 1-3) and phone call (week 4), as well as home visits as needed if no contacts are reached. These contacts are intended to provide encouragement and education to participants and families to encourage SAP and peer group attendance. Peer groups will have simple play and support activities, led by the village health team member, to improve the experience of SAP for the participating children.
Study: NCT05288218

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Leak-free Bronchoscope Adapter
Description: A novel leak-free bronchoscope adapter will connect to the ventilation circuit in place of a standard adapter.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Bronchoscope Adapter
Description: Commercially available bronchoscope adapter (Smiths Medical)