TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06757101

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vojta Therapy
Description: Exercises will be performed in supine, lateral, decubitus and reflex crawling. Exercises will include Stretching's, ROMs Exercises, Stimulation of 10 different zones for locomotion \& gentle pressure applied to stimulation areas. Frequency of exercises will be 2 times a week, duration 40 minutes per day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bobath Therapy
Description: Exercises will be performed in supine, lateral, prone and standing position. Exercises includes stretching Exercises, ROMs, Quadruped imbalance exercise, Imbalance from the kneeling exercise, Cervant Knight exercise, Tandem walk, Kicking a ball, Step climbing, marching at one place with alternate foot Frequency of exercises will be 2 times a week, duration 40 minutes per day.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined Vojta and Bobath Therapy
Description: Combined Vojta and Bobath exercises along with the conventional treatment. Frequency of exercises will be 2 times a week, duration 40 minutes per day.
Study: NCT06757712

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: non linear periodization exercise
Description: The non-linear periodized resistance training program follows a 12-week schedule with varying intensity levels across three training days per week. The intensity fluctuates between very light (VL), light (L), moderate (M), heavy (H), and very heavy (VH) workouts, distributed strategically throughout the week. Each training day implements different intensity levels, and an active rest day follows any workout session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: linear periodization exercise
Description: The linear periodization exercise program spans 12 weeks with systematically varied training parameters. During weeks 1-2, participants perform 3 sets of 10 repetitions, followed by 3 sets of 8 repetitions in weeks 3-4. The program progresses to 4 sets of 6 repetitions in weeks 5-6, then 3 sets of 6 repetitions during weeks 7-8. The final phases consist of 4 sets of 4 repetitions in weeks 9-10, concluding with 3 sets of 4 repetitions in weeks 11-12. Training loads advance through autoregulatory progression, where participants progress at their individual pace under supervision. While sets and repetitions remain fixed within each phase, load progression is determined by performance in the final set of each exercise, ensuring safe and effective advancement.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: medical treatment
Description: The medical treatment will be received for 12 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: medical treatment
Description: The medical treatment will be received for 12 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: medical treatment
Description: The medical treatment will be received for 12 weeks.
Study: NCT05055817

Intervention type: OTHER
Intervention: non-bloody stool group
Description: bloody stool do not appear in the hospitalized neonate
Study: NCT06756399

Intervention type: OTHER
Intervention: Questionnare, hand grip and respiratory muscle strength
Description: Upper extremity strength will be assessed using the Jamar hand dynamometer to measure hand grip strength. For lower extremity muscle strength, participants will undergo the five-repetition sit-to-stand test. Respiratory muscle strength, both inspiratory and expiratory, will be measured through mouth pressure assessments. Additionally, participants will complete a questionnaire addressing components related to sarcopenia diagnosis, including questions on strength, assistance with walking, rising from a chair, climbing stairs, and incidence of falls.
Study: NCT06756685

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core Strengthening Exercises
Description: The Core Strengthening Program participants will have supervised gym-based sessions for 8 weeks. In the first 4 weeks , participants will attend two 1 hour training sessions, followed by self-selected one or two sessions per week. The session will begin with 20min of aerobic conditioning of walking or running on a treadmill, starting at 65% and moving to 85% of HR max. The 5 key elements of focus are i. Centering ii. Breathing iii. Head and neck placement iv. Shoulder placement v. Chest wall placement

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Motor Control Training
Description: Participants in Motor Control group will receive two physiotherapy sessions of 1hour / week in the first 4 weeks, during stage 1. i. Abdominal drawing-in maneuver (ADIM) : isometric contraction of the local stability muscles (e.g., lumbar multifidus, transversus abdominis) in minimally loading positions (supine lying, quadruped, sitting, and standing) by maintaining a neutral spine while maintaining normal breathing. During Phase 2, One 1 hour session / week in the second 4 weeks.~Activation and facilitation of transversus abdominis, lumbar multifidus and pelvic floor motor control(36).Exercises target the transversus abdominis, multifidus and pelvic floor muscles plus postural correction to restore optimal motor control during non-weight-bearing activities. Exercises and progressions will follow previous protocols of motor control exercise.
Study: NCT06756893

Intervention type: PROCEDURE
Intervention: Dorsal Root Ganglion Pulsed Radiofrequency
Description: Using C-arm fluoroscopy, a 22G, 10 cm RF needle with a 5 mm active tip will be directed from lateral to medial towards the vertebral foramen. Once the needle reaches the lateral edge of the pedicle shadow, the C-arm will be adjusted to a lateral view to confirm that the needle is located at the craniodorsal portion of the intervertebral foramen. Sensory stimulation will be delivered through the RF generator at 50 Hz, and paresthesia will be sought in the corresponding dermatome at values between 0.4-0.8 mA.~After achieving paresthesia, motor stimulation at 2 Hz will be applied, and the location near the DRG will be confirmed if motor stimulation is not elicited at values less than 1.5 times the sensory threshold. Pulsed RF will then be applied for 4 minutes at a setting of 45 V, 20 ms pulse width, and 2 Hz frequency. Following the application, needle will be directed slightly anterior and after appropriate contrast flow, dexamethasone will be injected.
Study: NCT06757907

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acyclovir 400 MG
Description: Acyclovir is used to treat infections caused by certain types of viruses.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ganciclovir (GCV)
Description: Ganciclovir is an anti-viral drug
Study: NCT05280509

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Ruxolitinib is an FDA-approved janus kinase inhibitor anticancer drug taken by mouth.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Ruxolitinib is an FDA-approved janus kinase inhibitor anticancer drug taken by mouth.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Ruxolitinib is an FDA-approved janus kinase inhibitor anticancer drug taken by mouth.
Study: NCT06232785

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibuprofen
Description: 0.8g intravenous injection 30min before the end of the operation

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: sufentanil
Description: 0.2ug/kg intravenous injection 30min before the end of the operation
Study: NCT06756633

Intervention type: OTHER
Intervention: 6-Minute Peg Board Ring Test
Description: For Non-Ambulatory Participants:~The 6-Minute Pegboard Ring Test will be used to assess upper extremity exercise capacity . Pre- and post-test evaluations of heart rate, blood pressure, respiratory rate, and MBS for dyspnea and fatigue will be made. The board used for the test has a total of 6 holes spaced 10 cm apart horizontally and another set of 6 holes 20 cm below aligned with the top row. There are four 20 cm long iron rods suitable for the holes. A total of 20 rings suitable for the iron rods will be used. The iron rods will be placed in the designated holes according to the patients' shoulder width. An adjustable chair will be used to suit the patients' heights, and the distance between the chair and the board will be adjusted according to arm length. Patients will be asked to place the rings from top to bottom and bottom to top with both hands simultaneously. The total number of rings placed in six minutes will be recorded in units.

Intervention type: OTHER
Intervention: Hand Grip Strength
Description: Hand grip strength will be measured using a digital hand dynamometer (CAMRY Digital Hand Dynamometer) . The device handle will be adjusted according to the participants' hand size. The test is conducted while seated, with the dominant upper extremity in 90 degrees of elbow flexion. Participants are asked to squeeze the dynamometer as strongly as possible. The value displayed on the dynamometer is recorded. The measurement is repeated three times, and the average of the three measurements is taken to determine the participant's hand grip strength. The measurement takes five minutes and does not need to be repeated.
Study: NCT06262464

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prevention
Description: A cognitive-behavioural prevention programme.
Study: NCT06011369

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fluorescence in thyroid surgery
Description: Fluorescence in thyroid surgery
Study: NCT06043908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: artificial tear eyedrops
Description: The intervention group and control group were treated with artificial tear eyedrops four times a day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: artificial tear eyedrops
Description: The intervention group and control group were treated with artificial tear eyedrops four times a day.
Study: NCT06756633

Intervention type: OTHER
Intervention: Hand Grip Strength
Description: Hand grip strength will be measured using a digital hand dynamometer (CAMRY Digital Hand Dynamometer) . The device handle will be adjusted according to the participants' hand size. The test is conducted while seated, with the dominant upper extremity in 90 degrees of elbow flexion. Participants are asked to squeeze the dynamometer as strongly as possible. The value displayed on the dynamometer is recorded. The measurement is repeated three times, and the average of the three measurements is taken to determine the participant's hand grip strength. The measurement takes five minutes and does not need to be repeated.

Intervention type: OTHER
Intervention: Hand Grip Strength
Description: Hand grip strength will be measured using a digital hand dynamometer (CAMRY Digital Hand Dynamometer) . The device handle will be adjusted according to the participants' hand size. The test is conducted while seated, with the dominant upper extremity in 90 degrees of elbow flexion. Participants are asked to squeeze the dynamometer as strongly as possible. The value displayed on the dynamometer is recorded. The measurement is repeated three times, and the average of the three measurements is taken to determine the participant's hand grip strength. The measurement takes five minutes and does not need to be repeated.
Study: NCT06757920

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: bronchoscopic argon plasma coagulation
Description: Argon Plasma Cogulation for Debulking Endobronchial Carcinoid Using Fiberoptic Bronchoscopy
Study: NCT06758544

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oncolytic virus VRT106
Description: VRT106, IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: 21 days/cycle, administered up to 6 cycles
Study: NCT06758050

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core strengthening exercises
Description: By core strengthening exercise, could be improved pain, balance, and function in patients with patellofemoral pain syndrome. In that case, this will not only improve their postural stability and neuromuscular control, but we believe it will improve their overall functional, performance, and quality of life. Currently, limited evidence exists about the effectiveness of core strengthening exercises on pain, function and dynamic balance in patellofemoral pain syndrome. By addressing core strengthening exercise, physical therapists can advise new treatment methods for patellofemoral pain syndrome (Chevidikunnan et al., 2016)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional treatment
Description: hip and knee-focused exercises

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional treatment
Description: hip and knee-focused exercises
Study: NCT06756412

Intervention type: PROCEDURE
Intervention: Temporomandibular Joint Arthrocentesis
Description: The symptomatic temporomandibular joint (TMJ), either right or left, will be anesthetized using an auriculotemporal nerve block and intracapsular anesthesia. The arthrocentesis procedure will be performed using the double-puncture technique. A 21-gauge needle will be inserted into the posterior region of the joint capsule, targeting the upper joint compartment at a point located 10 mm anterior to the tragus. A second 21-gauge needle will be introduced into the anterior region of the joint capsule, also targeting the upper compartment, at a point located 20 mm anterior to the tragus. The upper joint compartment will then be irrigated with a minimum of 200 mL of saline solution through one of the needles.

Intervention type: PROCEDURE
Intervention: Self Exercise Following Arthrocentesis
Description: Following the arthrocentesis procedure described for the other study group, patients will undergo a standardized exercise regimen based on established literature. The regimen includes two sets of movements. The first set involves freely opening the jaw, shifting it right, left, and forward, and repeating these movements while applying finger resistance-closing the mouth against the pressure or forcing the jaw open with the fingers. Each movement will last 10 seconds and be performed 10 times daily. The second set aims to improve the mandibular condyle-articular disc relationship. Patients will open their mouth as wide as possible, advance their lower jaw fully, and close their teeth in an edge-to-edge position. These movements will be performed three times daily for 5 minutes after meals.
Study: NCT06757933

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: The Spencer technique
Description: The Spencer technique, which consists of seven different manual movements intended to increase shoulder mobility and lessen pain, was used to treat the participants in this group. The method seeks to improve blood flow, loosen up the shoulder joint and soft tissues, and reduce any tightness or impingement that is causing pain in the sub-acromial area. By re-establishing appropriate shoulder function and movement patterns, the Spencer approach is commonly used to treat disorders including adhesive capsulitis.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: isotonic workouts
Description: This group's members engaged in isotonic workouts that emphasized forward flexion and extension motions. Both concentric (shortening the muscle) and eccentric (lengthening the muscle) motions were used in these exercises. These exercises were designed to increase shoulder range of motion and strengthen the rotator cuff muscles. People with Adhesive Capsulitis may have less pain and have better shoulder function if they perform isotonic workouts, which increase muscular strength and stability.
Study: NCT06757569

Intervention type: DEVICE
Group type: OTHER
Intervention: PET
Description: Feasibility assessment of using the Radialis PET Imager for the detection of amyloid plaque burden using PET amyloid tracer.
Study: NCT06758024

Intervention type: DRUG
Group type: OTHER
Intervention: Infliximab
Description: IFX therapeutic drug monitoring before the second and third infusion and subsequent dashboard-guided dosing regimes suggested to attending gastroenterologists based on clinical and pharmacokinetics data
Study: NCT06043908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.05% cyclosporine eyedrops
Description: The intervention group was treated twice a day.
Study: NCT04489082

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near Infrared Laser Stimulation
Description: 10 minutes of transcranial near infrared laser stimulation
Study: NCT06249061

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: oral sodium bicarbonate
Description: Those in the oral sodium bicarbonate intervention group will be encouraged to sip a solution of 1 imperial teaspoon (\~5g) of sodium bicarbonate dissolved into 250ml of water throughout labour with other drinks. If the first solution is fully consumed, a second solution will be prepared and offered. Thus, each participant can receive a maximum dose of 2 imperial teaspoons (\~10g) of sodium bicarbonate.
Study: NCT05114733

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: InVEST
Description: Individualized vocational and educational support and training -- participant works with BA level school/ work coach for four months
Study: NCT04622241

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eave Tubes
Description: The eave tubes are PVC tubes with a diameter of 15 cm installed in the outer wall of occupied rooms (e.g. bedrooms and living rooms but not storage rooms) at 1.5-2 m intervals, fitted with electrostatic mesh inserts coated with insecticides. No additional screening will be done. All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eave Tubes
Description: The eave tubes are PVC tubes with a diameter of 15 cm installed in the outer wall of occupied rooms (e.g. bedrooms and living rooms but not storage rooms) at 1.5-2 m intervals, fitted with electrostatic mesh inserts coated with insecticides. No additional screening will be done. All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.
Study: NCT06003153

Intervention type: DRUG
Group type: OTHER
Intervention: oral semaglutide
Description: Semaglutide is the only oral glucagon-like peptide 1 receptor agonist (GLP-1 RA) approved for treatment of type 2 diabetes. Participants will receive 7 mg of oral semaglutide once daily for 14 days in between Visit 1 and Visit 2.
Study: NCT06003153

Intervention type: OTHER
Group type: OTHER
Intervention: Mixed Meal Tolerance Test (MMTT)
Description: The MMTT is developed by the Metabolism and Nutrition Metabolic Kitchen at the MGH TCRC. The meal is a high-calorie, high-carbohydrate and moderate-to-high glycemic index challenge composed of commonly consumed breakfast food items. It provides nearly 90 grams of carbohydrates and mimics an oral glucose challenge. The participants will undergo a MMTT at Visit 1 and Visit 2.
Study: NCT05280509

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Ruxolitinib is an FDA-approved janus kinase inhibitor anticancer drug taken by mouth.
Study: NCT06058195

Intervention type: PROCEDURE
Intervention: Quadratus lumborum plane block
Description: QLB (quadratus lumborum plane block): 20 ml of 0.25% bupivacaine will be used each time for plane block on both sides. Patients will be sedated with 1 mg midazolam and 50 mcg fentanyl intravenously in the preoperative preparation room in the operating room and 20 ml of 0.25% bupivacaine was administered bilaterally on each side under ultrasound guidance. After the block application, the patient was taken to the operating room and standard general anaesthesia was applied.

Intervention type: PROCEDURE
Intervention: Transverse abdominis plane block
Description: TAPB (transverse abdominis plane block): 20 ml of 0.25% bupivacaine will be used each time for plane block on both sides. Patients will be sedated with 1 mg midazolam and 50 mcg fentanyl intravenously in the preoperative preparation room in the operating room and 20 ml of 0.25% bupivacaine was administered bilaterally on each side under ultrasound guidance. After the block application, the patient was taken to the operating room and standard general anaesthesia was applied.

Intervention type: PROCEDURE
Intervention: Intravenous analgesia
Description: IVA (Intravenous analgesia): These patients will be administered 1000 mg paracetamol intravenously in the preoperative waiting room in the operating room approximately 20-30 minutes before induction of anaesthesia. No block procedure will be performed. Patients will not be given any analgesic medication before awakening from anaesthesia.
Study: NCT06458894

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Prerehabilitation
Description: Home prerehabilitation was performed on the basis of routine preoperative preparation

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Prerehabilitation
Description: Home prerehabilitation was performed on the basis of routine preoperative preparation
Study: NCT04622241

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Partial House Screening
Description: Partial screening will include either screening of the eaves or installing a screened ceiling, where no ceiling is present. In traditional houses, a netting (either insecticide-impregnated or untreated) may be either fixed in multiple places in the rafters or by hanging from a single central point and attached to the walls. No other screening or filling of the gaps will be done in partially screened houses.All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.
Study: NCT04557228

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 4 weeks of placebo supplements

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Phosphatidylserine
Description: 4 weeks of phosphatidylserine supplements
Study: NCT06096727

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Energize!
Description: Energize! is 3 month online physical activity program which consists of weekly physical activity goals, video lessons, action planning, and homework.
Study: NCT05725681

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High protein ramen
Description: Participants will be served one portion of high-protein instant ramen noodles \[CHEF WOO Roasted Chicken Flavor Ramen Cup Noodles, Borealis Foods; 71 g\]

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard ramen
Description: Participants will be served one portion of standard instant ramen noodles \[RAMEN EXPRESS Chicken Flavor Ramen Cup Noodle Chef Woo, Borealis Foods; 71 g\]
Study: NCT06758024

Intervention type: DRUG
Group type: OTHER
Intervention: Infliximab
Description: No IFX therapeutic drug monitoring before the second and third infusion and subsequent dosing regimes based on clinical data
Study: NCT06757088

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: M1 Stimulation Group
Description: For M1, the anodal electrode will be placed over M1 region while the cathodal electrode will be placed over the right contralateral supraorbital region.
Study: NCT06096727

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Energize!
Description: Energize! is 3 month online physical activity program which consists of weekly physical activity goals, video lessons, action planning, and homework.