TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06759610

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tetracyclin
Description: to evaluate the effect of tetracycline socked pack on acceleration of healing during marsupialization as a primary treatment for locally invasive lesions.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tetracyclin
Description: to evaluate the effect of tetracycline socked pack on acceleration of healing during marsupialization as a primary treatment for locally invasive lesions.
Study: NCT06043791

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 1.5 Tesla magnet MR arthrography
Description: MR arthrogram is an invasive procedure where the patient's joint is injected with a mixture of dilute gadolinium, iodinated contrast medium, local anesthetic, and saline solution followed by imaging with 1.5 Tesla MRI.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 3 Tesla magnet non-contrast MRI
Description: 3T MRI uses very powerful magnets that produce a 3-tesla magnetic field. A 3-tesla magnetic field is twice as powerful as the fields used in conventional high-field MRI scanners, and as much as 15 times stronger than low-field or open MRI scanners. This results in a clearer and more complete image. Studies have shown that it is highly sensitive and specific in detecting labral and cartilage pathology
Study: NCT05569330

Intervention type: OTHER
Group type: OTHER
Intervention: Air purification
Description: Aerosol particles are removed from room air by several methods

Intervention type: OTHER
Group type: OTHER
Intervention: Air purification
Description: Aerosol particles are removed from room air by several methods
Study: NCT05176379

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Fluconazole 150 mg
Description: A single acute 150 mg dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluconazole 150 mg
Description: A single acute 150 mg dose
Study: NCT04821154

Intervention type: DEVICE
Intervention: Persona Revision Knee System
Description: Patients in this cohort will have been previously implanted with the Persona Revision Knee system in the described configuration per standard of care. The Persona Revision knee system is a total knee system that is widely available for use in the United States and is designed for use in primary and revision knee surgical interventions.

Intervention type: DEVICE
Intervention: Persona Revision Knee System
Description: Patients in this cohort will have been previously implanted with the Persona Revision Knee system in the described configuration per standard of care. The Persona Revision knee system is a total knee system that is widely available for use in the United States and is designed for use in primary and revision knee surgical interventions.
Study: NCT06071494

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tropical fruits
Description: papaya, mango, banana, orange
Study: NCT05924776

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Plasmodium immunotherapy
Description: Inoculation 1-5 × 10\^6 Plasmodium vivax once
Study: NCT06291181

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: antibiotic sensitivity test
Description: Disc diffusion method using modified Kirby-Bauer technique on Muller Hinton agar (MHA) will be carried out for antimicrobial susceptibility of S. aureus isolates. The following antibiotics will be tested: cefoxitin (30 µg ), Tetracyclin 30 µg (TE), Chloramphenicol 30 µg (C), Gentamycin 10µg (CN), Erythromycin 15µg(E),Clindamycin 2 µg (DA), Ciprofloxacin 5 µg (CIP), Trimethoprim/sulphamethoxazole 1.25/23.75 µg (SXT), Rifampin 5µg (RA), Linezolide 30µg (LZD); cefoxitin disc (FOX 30 g)~zone diameters interpretation will be done according to Clinical and Laboratory Standard Institute (CLSI 2018),
Study: NCT06443853

Intervention type: DIAGNOSTIC_TEST
Intervention: Dental plaque scoring and dental plaque coated tooth surface measuring
Description: The Turesky Modified Quigley Hein Plaque Index of anterior teeth of the volunteers' was recorded using clinical visual examination.~Intraoral photographs of the volunteers were taken by using a digital camera and 3D images were recorded by an intraoral scanner. The plaque-covered area and the total surface area of the teeth were marked in the manual mode of the Image J program and the areas were measured in square pixels. The correlation between clinical visual scoring, dental plaque areas on images were compared.

Intervention type: DIAGNOSTIC_TEST
Intervention: Dental plaque scoring and dental plaque coated tooth surface measuring
Description: The Turesky Modified Quigley Hein Plaque Index of anterior teeth of the volunteers' was recorded using clinical visual examination.~Intraoral photographs of the volunteers were taken by using a digital camera and 3D images were recorded by an intraoral scanner. The plaque-covered area and the total surface area of the teeth were marked in the manual mode of the Image J program and the areas were measured in square pixels. The correlation between clinical visual scoring, dental plaque areas on images were compared.

Intervention type: DIAGNOSTIC_TEST
Intervention: Dental plaque scoring and dental plaque coated tooth surface measuring
Description: The Turesky Modified Quigley Hein Plaque Index of anterior teeth of the volunteers' was recorded using clinical visual examination.~Intraoral photographs of the volunteers were taken by using a digital camera and 3D images were recorded by an intraoral scanner. The plaque-covered area and the total surface area of the teeth were marked in the manual mode of the Image J program and the areas were measured in square pixels. The correlation between clinical visual scoring, dental plaque areas on images were compared.
Study: NCT06464172

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acute Oral gamma-aminobutyric acid (Natural Health Product in Canada)
Description: 1800 mg (3 capsules of 600mg) of GABA taken at the research center under the supervision of the research team.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acute Oral gamma-aminobutyric acid (Natural Health Product in Canada)
Description: 1800 mg (3 capsules of 600mg) of GABA taken at the research center under the supervision of the research team.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acute Placebo
Description: A capsule filled with powdered sugar taken under the supervision of the research team.
Study: NCT06547931

Intervention type: OTHER
Intervention: Data collection and analysis
Description: Retrospective collection of clinical and laboratory data relating to the definition of the nature of neutropenia
Study: NCT05014984

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mental contrasting with implementation intentions
Description: To deliver MCII, Dr. Oettingen developed a step-wise procedure called WOOP (Wish, Outcome, Obstacle, Plan; Figure 1).36 In a quiet setting, patients identify an important wish (e.g., losing weight) and then name and vividly imagine the best outcome (e.g., feeling healthier). Next, they name a current internal obstacle (e.g., urge to eat when feeling stressed) and try to vividly imagine their experience when they encounter this obstacle. Finally, they address their obstacle with an if-then plan specifying when, where, and how to overcome it (e.g., If I have the urge to eat when feeling stressed, I will go for a walk) and then imagine themselves experiencing the obstacle and carrying out the action of surmounting it. To facilitate use of the WOOP technique, Dr. Oettingen developed a free, publicly available WOOP app

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: telephone-delivered, telehealth-delivered, and or in-person MOVE! or TeleMOVE!
Description: MOVE! is a national VA weight management and health promotion program to improve the quality of life of Veterans.6,75 This effective program encourages healthy eating behavior and increased physical activity. MOVE! will be delivered via telephone (16 sessions) by existing staff consistent with national MOVE! program guidelines. The program has 16 modules and will offered weekly, but Veterans will be able to make up sessions at their own pace if they miss one. MOVE! staff use the MOVE! facilitator guide that provides instruction on delivering the program via telephone. Update as of 11-2023, the New York Harbor VA paused their offering of telephone-delivered MOVE!. Participants in both arms are offered the in-person or video-delivered MOVE! program. For participants who do not want or are unable to attend group-based MOVE!, they are offered TeleMOVE!.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: telephone-delivered, telehealth-delivered, and or in-person MOVE! or TeleMOVE!
Description: MOVE! is a national VA weight management and health promotion program to improve the quality of life of Veterans.6,75 This effective program encourages healthy eating behavior and increased physical activity. MOVE! will be delivered via telephone (16 sessions) by existing staff consistent with national MOVE! program guidelines. The program has 16 modules and will offered weekly, but Veterans will be able to make up sessions at their own pace if they miss one. MOVE! staff use the MOVE! facilitator guide that provides instruction on delivering the program via telephone. Update as of 11-2023, the New York Harbor VA paused their offering of telephone-delivered MOVE!. Participants in both arms are offered the in-person or video-delivered MOVE! program. For participants who do not want or are unable to attend group-based MOVE!, they are offered TeleMOVE!.
Study: NCT06464172

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acute Placebo
Description: A capsule filled with powdered sugar taken under the supervision of the research team.
Study: NCT05014984

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Information About Diet, Physical Activity, and Weight Management (Baseline Visit - 10 minutes): All
Description: All participants will receive handouts that they review with a lay educator on weight management, adapted from the educational materials developed for our FIReWoRk Study.Topics include losing weight at a healthy rate, setting a 6-month weight loss goal of 5-10%, limiting sugar-sweetened beverages and portion sizes, making better choices when eating at restaurants, self-monitoring diet and weight, and participating in at least moderate-intensity physical activities.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Information About Diet, Physical Activity, and Weight Management (Baseline Visit - 10 minutes): All
Description: All participants will receive handouts that they review with a lay educator on weight management, adapted from the educational materials developed for our FIReWoRk Study.Topics include losing weight at a healthy rate, setting a 6-month weight loss goal of 5-10%, limiting sugar-sweetened beverages and portion sizes, making better choices when eating at restaurants, self-monitoring diet and weight, and participating in at least moderate-intensity physical activities.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telephone MCII Check-ins (30 minutes at 3 days, 4 weeks, and 2 months after baseline visit)
Description: The lay educator will review and practice the WOOP technique based on protocols from prior studies.12 To probe Veterans' comprehension, the lay educator will ask for their four steps and ask about their WOOP use and experiences. If needed, the lay educator will help the Veteran to create a new WOOP for the next month and address any questions and concerns about using WOOP.
Study: NCT05619107

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Transauricular nerve stimulation
Description: The first allocated intervention will be undertaken for 30 minutes. The electrode placement and stimulation parameters are described in the arm/group section. After the 30-minute intervention, day 1 of the protocol will be complete. The investigator will remain present in the room with the participant to ensure compliance and adherence to the protocol. The allocated intervention will then be repeated by the participant at a similar time of day for 7 consecutive days. The investigator will arrange video-calls with the participant whilst off-site to ensure ongoing compliance and adherence to the protocol. On the seventh day, participants return to the clinical research facility to take the final first allocated intervention. A 14-day rest period will follow. Then the participants will perform the same 7-day protocol for the opposite intervention to their first treatment allocation.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transauricular nerve stimulation
Description: Protocol as for active but sham ear leads are applied, unable to deliver current.
Study: NCT04827836

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cooled eye drops and povidone-iodine
Description: Cooled oxybuprocaine HCl 0.4% and lidocaine HCl 2% eye drops and cooled povidone-iodine (cul-de-sac 5% povidone-iodine and 10% povidone-iodine).
Study: NCT06552559

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Combination chemotherapy
Study: NCT06187987

Intervention type: DEVICE
Intervention: Mechanical thrombectomy
Description: Aspirational mechanical thrombectomy

Intervention type: DRUG
Intervention: Intravenous thrombolysis
Description: Intravenous thrombolysis with tissue-type plasminogen activator (tPA)
Study: NCT06310785

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: The esketamine group used esketamine as an analgesic during induction and maintenance of anesthesia.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sufentanil
Description: In the opioid group, sufentanil was used as an analgesic during anesthesia induction and remifentanil was used as an analgesic during anesthesia maintenance.
Study: NCT05667480

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR-based script training
Description: The PWA will wear a head-mounted VR device (e.g., Metaverse Oculus Quest 2 or other commercially available devices) for 30 minutes, which intends to create an immersive environment for training. Scripts trained in the computerized script training program in a particular session will be practiced. Cinematic 360˚ photo-real scenarios of daily contexts such as a restaurant or a grocery store will be displayed in the device while a communication partner, e.g., a waiter in the restaurant or a shopkeeper of a grocery store will initiate the conversation by producing the corresponding part of the script. The PWA will be given time to respond. Upon the completion of PWA's respond, the next conversational turn will be initiated. The clinical assistant, who accompanies the PWA in the entire training session, will control the flow of the 360 ˚ videos.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional script training
Description: The flow of training is identical to the VR condition, except that photos depicting the scenarios and pre-recorded conversational turns will be presented to the PWA on a computer screen with the same procedures mentioned in the VR condition.
Study: NCT06401174

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Delivery of patient navigation
Description: Clinics will receive educational materials and access a referral order for patient navigation. Iterative strategies will be used to increase CRC screening
Study: NCT06070415

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Chatbot
Description: 12 week- intervention consisting of messages with an explanatory video of each exercise indicating how to do it and how many repetitions to perform
Study: NCT06424717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avelumab
Description: Participants will be administered Avelumab intravenously (IV).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tuvusertib
Description: Participants will be administered Tuvusertib orally.
Study: NCT06070415

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home exercise, usual care
Description: 12 week- intervention. Printed sheets indicating how to exercises and how many repetitions to perform
Study: NCT05312086

Intervention type: OTHER
Group type: OTHER
Intervention: MRI
Description: Performing the muscle MRI requires the cooperation of the child in order to remain lying down and motionless throughout the duration of the MRI, about 45 minutes.~Performing MRI does not require the injection of contrast products or radiopharmaceuticals.

Intervention type: OTHER
Group type: OTHER
Intervention: MRI
Description: Performing the muscle MRI requires the cooperation of the child in order to remain lying down and motionless throughout the duration of the MRI, about 45 minutes.~Performing MRI does not require the injection of contrast products or radiopharmaceuticals.
Study: NCT05536037

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy
Study: NCT04593212

Intervention type: DIAGNOSTIC_TEST
Intervention: Optical Coherence Tomography Angiography
Description: Evaluation of microcirculatory dysfunction by assessment of retinal and choroidal microvasculature with optical coherence tomography angiography (OCTA)

Intervention type: DIAGNOSTIC_TEST
Intervention: Optical Coherence Tomography Angiography
Description: Evaluation of microcirculatory dysfunction by assessment of retinal and choroidal microvasculature with optical coherence tomography angiography (OCTA)
Study: NCT06070415

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: One-week, three sessions in alternate days, outpatient supervised education on how to perform the exercises at home
Study: NCT05801302

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Foam rolling (shorter volume)
Description: A single intervention will be performed (3 sets of 30 seconds, with between-sets intervals of 30 seconds).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Foam rolling (longer volume)
Description: A single intervention will be performed (3 sets of 60 seconds, with between-sets intervals of 30 seconds).
Study: NCT06070415

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: One-week, three sessions in alternate days, outpatient supervised education on how to perform the exercises at home
Study: NCT06656689

Intervention type: PROCEDURE
Intervention: Rezum (water vapor thermal therapy)
Description: Rezum or water vapor thermal therapy is a procedure that involves injecting steam at 103°C into the prostate tissue to induce necrosis and reduce the size of the enlarged prostate.
Study: NCT06677268

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: rehabilitation
Description: Patients will undergo a respiratory rehabilitation program (24 exercise sessions of 90 minutes each, three times a week for 8 weeks and up to 9 therapeutic education workshops of 1 hour of the patient\&#39;s choice)
Study: NCT06677294

Intervention type: PROCEDURE
Intervention: Placenta remove
Description: This is an observational study. No intervention was performed

Intervention type: PROCEDURE
Intervention: Placenta remove
Description: This is an observational study. No intervention was performed
Study: NCT06676332

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: motor imagery training
Description: Children in the study group will receive multisensory motor imagery training program 45 minutes. The training protocol consists of several parts that will be run through every training session according to Kumar et al. (2016):~* Watching videos of selected multisensory motor skills for 10 minutes.~* Mental rehearsal of these motor skills 10 minutes.~* Overt practice of the multisensory motor skills for 25 minutes. On the videos, the performance of the skill by a child aged 8-12 years will be shown. All the exercises will be looped to repeat for six to seven times. While projecting the video on the laptop screen, it will be ensured that the children are in a comfortable seating position and the screen is in their visual field. Repetition of the exercises was based on their ability which could be a minimum of five repetitions per session to a maximum of ten repetitions per exercise session.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: traditional physical therapy
Description: traditional physical therapy training program

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional physical therapy
Description: traditional physical therapy training program
Study: NCT05455268

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Face-to-face verbal discussions and caregiver training will be provided as deemed necessary by the clinicians.
Study: NCT06677333

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whey Protein
Description: This intervention will add 50 g of a whey or pea protein supplement to their usual dietary intake.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pea protein
Description: This intervention will add 50 g of a pea protein supplement to their usual dietary intake.
Study: NCT06677138

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gefurulimab
Description: Participants will receive gefurulimab subcutaneously (SC).
Study: NCT05455268

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Face-to-face verbal discussions and caregiver training will be provided as deemed necessary by the clinicians.
Study: NCT06677528

Intervention type: OTHER
Intervention: Questionnaire
Description: Questionnaire on Aortic Valve Disease, HADS-D, SCL-27, MLHFQ
Study: NCT06631872

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-prehabilitation education session: Surgery School
Description: Online telehealth education program using videos and a live clinician facilitator
Study: NCT04622787

Intervention type: OTHER
Intervention: Knowledge translation
Description: A. Healthcare Providers Observational Study - measure of the effectiveness of the International Guidelines training courses (face to face and online) delivered to medical professionals (involves all clinical partners).~The International Guidelines training courses on the evidence-based principles of Early Detection (ED), Early surveillance (ES), and Early intervention (EI) will be delivered to healthcare providers.~Face-to-face professional trainings will be set up at each Consortium partner location. E-learning platform will allow for training and follow-up resources will be available to clinicians in all languages that are spoken/written in the locations of the Consortium partners.~Clinicians will be assessed on their knowledge and standard clinical practices in survey format before trainings and after the trainings.
Study: NCT06075784

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: reiki
Description: placebo reiki

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: reiki
Description: placebo reiki
Study: NCT06032130

Intervention type: OTHER
Intervention: Clinical measurements
Description: Optometric measurements

Intervention type: OTHER
Intervention: Clinical measurements
Description: Optometric measurements

Intervention type: OTHER
Intervention: Clinical measurements
Description: Optometric measurements

Intervention type: OTHER
Intervention: Oculomotor or perceptual therapy
Description: Oculomotor or perceptual visual learning exercices