TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06344975

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: STR-V003/Placebo
Description: IM

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: STR-V003/Placebo
Description: IM

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: STR-V003/Placebo
Description: IM

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: STR-V003/Placebo
Description: IM
Study: NCT05056402

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 3 doses of the Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)
Description: Three doses administered intramuscularly at 0, 1 and 6 month.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 3 doses of the Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)
Description: Three doses administered intramuscularly at 0, 1 and 6 month.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2 doses of theRecombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)
Description: Two doses administered intramuscularly at 0 and 6 month.
Study: NCT04715438

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273 SARS-CoV-2 vaccine from Moderna
Description: All participants will receive two vaccinations against COVID-19 according to standard of care.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273 SARS-CoV-2 vaccine from Moderna
Description: All participants will receive two vaccinations against COVID-19 according to standard of care.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273 SARS-CoV-2 vaccine from Moderna
Description: All participants will receive two vaccinations against COVID-19 according to standard of care.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273 SARS-CoV-2 vaccine from Moderna
Description: All participants will receive two vaccinations against COVID-19 according to standard of care.
Study: NCT05785923

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Point-of-Care Echocardiogram
Description: Four view ultrasound of the heart performed at the bedside by trained emergency medicine physicians.
Study: NCT05619497

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Clinic-wide Trainings
Description: The clinic-wide trainings combine principles of shared decision-making and trauma informed care to inform providers and clinic staff of an equitable approach to offering HIV prevention information. These care delivery approaches have been used in health education and counseling in a range of contexts and are effective strategies for care provision. Participants in this arm will receive care from providers and staff who received training.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST)
Description: The clinic-wide trainings combine principles of shared decision-making and trauma informed care to inform providers and clinic staff of an equitable approach to offering HIV prevention information. These care delivery approaches have been used in health education and counseling in a range of contexts and are effective strategies for care provision. Participants in this arm will receive care from providers and staff who received training.~The DST is founded on principles of decision-science and will address barriers to PrEP delivery. The DST will present HIV prevention information through a tablet in the clinical setting. The tool provides information about vulnerabilities to HIV and core characteristics of different HIV prevention methods, and the opportunity to explore these characteristics in depth, including efficacy, safety and side effects. The tool emphasizes the highly variable and individual nature of baseline risk.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care with the HIV Prevention Decision Support Tool (DST)
Description: Participants in this arm will receive usual care at a clinic that has not received training in shared decision making and trauma informed care. These participants will view the decision support tool. These participants were recruited in Aim 1 of this study.
Study: NCT06160687

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PSV mode during NIV
Description: NIV will be delivered using PSV mode of ventilation

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ASV intellisync
Description: ASV intellisync mode will be used to deliver NIV
Study: NCT06415526

Intervention type: PROCEDURE
Intervention: OPERA
Description: Robotic-assisted mastectomy and robotic assisted free DIEP flap harvest for breast reconstruction
Study: NCT05584683

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: amoxicillin-clavulanic acid
Description: Reconstituted amoxicillin/clavulanate oral suspension, LP-001, a new fixed dose combination will be administered in a single dose
Study: NCT04577001

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Description: 2.5 mg orally daily for 6 months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: No active ingredient taken orally daily for 6 months
Study: NCT06203353

Intervention type: DIAGNOSTIC_TEST
Intervention: diaphragm ultrasound monitoring
Description: Ultrasound measure the diaphragm excursion, thickening fraction and maximal contraction and relaxation velocities

Intervention type: DIAGNOSTIC_TEST
Intervention: diaphragm ultrasound monitoring
Description: Ultrasound measure the diaphragm excursion, thickening fraction and maximal contraction and relaxation velocities
Study: NCT05355857

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: brain PET-MRI with 18F-FDG
Description: Realisation of a brain PET-MRI with 18F-FDG in 39 healthy volunteers
Study: NCT06696027

Intervention type: DIAGNOSTIC_TEST
Intervention: Single nucleotide polymorphisms (SNP)
Description: Utilizing single nucleotide polymorphisms (SNP) genotyping mosaic loss of y (mLOY) of individual patient will be assessed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Single nucleotide polymorphisms (SNP)
Description: Utilizing single nucleotide polymorphisms (SNP) genotyping mosaic loss of y (mLOY) of individual patient will be assessed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Single nucleotide polymorphisms (SNP)
Description: Utilizing single nucleotide polymorphisms (SNP) genotyping mosaic loss of y (mLOY) of individual patient will be assessed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Single nucleotide polymorphisms (SNP)
Description: Utilizing single nucleotide polymorphisms (SNP) genotyping mosaic loss of y (mLOY) of individual patient will be assessed.

Intervention type: DIAGNOSTIC_TEST
Intervention: Single nucleotide polymorphisms (SNP)
Description: Utilizing single nucleotide polymorphisms (SNP) genotyping mosaic loss of y (mLOY) of individual patient will be assessed.
Study: NCT05439421

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Package/Advertisement With Claim
Description: Waterpipe tobacco packages and digital marketing advertisement images with claim of interest as part of design

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Package/Advertisement With Claim
Description: Waterpipe tobacco packages and digital marketing advertisement images with claim of interest as part of design
Study: NCT06694675

Intervention type: DRUG
Intervention: Sevoflurane (Volatile Anesthetic)
Description: Sevoflurane 1%\~3.5%
Study: NCT06263647

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Houston-HVIP treatment
Description: Participants will be assigned a case manager provide a brief assessment of psychological and social needs and individualized discharge planning bedside and will receive coordinated referral, networking, and close follow-up with community-level violence outreach organizations from the City of Houston Mayor's Office and the Health Equity Collective and will be referred for program enrollment to the Forgotten Third for credible messenger intervention and concurrent tailored intervention programs based on individual needs. Trauma counseling and referrals to tailored social service programs based on the patient's needs and follow-up contacts and services from an assigned case manager over 12 months following discharge from the hospital to ensure continuity of care and services. This will include ongoing case coordination and motivational interviewing to promote successful community-based program integration and completion will also be provided.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Case Management
Description: Participants will receive expanded case management services tailored to their personal needs and ongoing monitoring for three months for motivational interviewing, case coordination, social determinants of health referrals and referral for community-based resources. Based on each patient's needs, case managers will remain involved in the case past three months if needed.
Study: NCT04705012

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Submucosal supportive therapy
Description: Increased frequency of submucosal cleaning using a rotating chitosan brush

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Submucosal supportive therapy
Description: Increased frequency of submucosal cleaning using a rotating chitosan brush
Study: NCT06444503

Intervention type: OTHER
Intervention: Biological samples
Description: Blood and urine will be taken in larger quantity

Intervention type: OTHER
Intervention: Biological
Description: Surgical residues may be preserved in the event of surgery carried out as part of the treatment.
Study: NCT06010602

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus lumborum block
Description: For all patients, postoperative analgesia was planned as paracetamol 1g four times a day for the first 24 hours after surgery. Patients with Numeric Rating Scale (NRS) scores greater than 3 at 2, 4, 8, 12, and 24 hours postoperatively were administered rescue analgesia with tramadol hydrochloride at a dose of 1mg/kg.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: İlioinguinal-İliohipogastric nerve block
Description: For all patients, postoperative analgesia was planned as paracetamol 1g four times a day for the first 24 hours after surgery. Patients with Numeric Rating Scale (NRS) scores greater than 3 at 2, 4, 8, 12, and 24 hours postoperatively were administered rescue analgesia with tramadol hydrochloride at a dose of 1mg/kg.
Study: NCT06694675

Intervention type: DRUG
Intervention: Sevoflurane (Volatile Anesthetic)
Description: Sevoflurane 1%\~3.5%

Intervention type: DRUG
Intervention: propofol
Description: Propofol 9\~15mg/kg/h

Intervention type: DRUG
Intervention: propofol
Description: Propofol 9\~15mg/kg/h
Study: NCT06630260

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avutometinib
Description: Supplied as 0.8mg capsules.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avutometinib
Description: Supplied as 0.8mg capsules.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Defactinib
Description: Supplied as 200mg tablets.
Study: NCT05199467

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Coaching
Description: Health coaches help people focus on goals, identify strengths and values, and work towards building the kind of life they wish to live.
Study: NCT06630260

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Defactinib
Description: Supplied as 200mg tablets.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide will be supplied as 5, 20, 100, 140, 180 or 250 mg hard capsules.
Study: NCT06688227

Intervention type: OTHER
Group type: OTHER
Intervention: Isolated Core Stability Program
Description: The control group consists of basic core exercises which include the activation of transversusabdominins and multifidus muscles and progressive strengethening of these muscles in all positions using swiss balls and floor mats. All exercises were done for at least 3 sets of 15 repetitions to build proper core stability.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated Core Stability Program
Description: An individualized protocol was designed for these cricketers targeting static and dynamic core stability, with integration of balance, endurance and power component.~Tranversusabdominis and multifidus strengthening is combined with upper extremity motions to work on the fast bowling action i.e throwing of the players.~At the same time lower extremity balance and strengthening is also included to ensure the high speed of sprint.
Study: NCT06687564

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: A skin biopsy and a blood sample will be taken to culture the iPS cells and intestinal organoids.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Biopsy
Description: A skin biopsy and a blood sample will be taken to culture the iPS cells and intestinal organoids.
Study: NCT06688266

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nerve Gliding Exercises
Description: This group will receive 25-minute session of nerve gliding exercises per session five days a week for six weeks. It will include: Warm-Up (5 minutes)~Neural Gliding of the upper quadrant:~Median nerve glide (5 minutes) Ulnar nerve glide (5 minutes) Radial nerve glide (5 minutes) Cool Down (5 minutes)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hand Grip Strength Exercises
Description: This group's participants will also receive a 25 -minute session five days per week (for six weeks). Warm-Up (5 minutes) Conventional Grip Strength Exercises (15 Minutes)~* Tendon gliding sequence of exercises for hand~* Squeezing a rubber ball or stress ball~* Dead Hang Cool Down (5 Minutes)
Study: NCT06691113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itepekimab (SAR440340)
Description: Pharmaceutical form: Solution for injection in prefilled syringe. Route of administration: Subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itepekimab (SAR440340)
Description: Pharmaceutical form: Solution for injection in prefilled syringe. Route of administration: Subcutaneous
Study: NCT05199467

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VA Benefits Information
Description: Printed materials with information on VA benefits.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: VA Benefits Information
Description: Printed materials with information on VA benefits.
Study: NCT06691113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Pharmaceutical form: Solution for injection in prefilled syringe. Route of administration: Subcutaneous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form: Solution for injection in prefilled syringe. Route of administration: Subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mometasone furoate nasal spray (MFNS)
Description: Pharmaceutical form: Solution for administration via spray pump. Route of administration: Subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mometasone furoate nasal spray (MFNS)
Description: Pharmaceutical form: Solution for administration via spray pump. Route of administration: Subcutaneous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Mometasone furoate nasal spray (MFNS)
Description: Pharmaceutical form: Solution for administration via spray pump. Route of administration: Subcutaneous
Study: NCT04862650

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given IV
Study: NCT05968963

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Music Therapy (MBMT)
Description: Participants will receive 8 music therapy sessions that will last approximately 60 minutes in length. A Music therapist will conduct the sessions. These sessions will be in person and/or virtual depending on patient status and the time between sessions will vary based on patient response to treatment.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Meditation (MM)
Description: Participants will receive 8 mindfulness meditation sessions that will last approximately 60 minutes in length. These sessions will be participant led virtually.
Study: NCT05998616

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Training Program
Description: The intervention group will be encouraged to complete aerobic and resistance training exercises three times a week, and either at home, in the community (e.g., park, shopping mall), or any suitable environment of the participant's choice. Exercise equipment for monitoring walking and complete resistance training will be provided to the intervention group. The exercise training prescription involves 30+ minutes of moderate-intensity walking (≥100 steps/min) monitored by a waist-worn pedometer, and resistance training consisting of 1-2 sets, 10-15 repetitions of 5-10 exercises targeting lower and upper body, and core muscle groups using elastic bands.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Flexibility Program
Description: The control group will be encouraged to complete stretching and range of motion exercises three times a week, and either at home, in the community (e.g., park, shopping mall), or any suitable environment of the participant's choice. Exercise equipment (yoga mat) for monitoring walking and complete flexibility training will be provided to the control group. The flexibility training prescription involves stretches from the Stretching for People with MS: An Illustrated Manual from the National MS Society.
Study: NCT06696443

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Suzetrigine
Description: Tablets for oral administration.
Study: NCT05695495

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (5mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (5mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (10mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (10mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (15mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (15mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (20mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (20mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N,N-Dimethyltryptamine (25mg)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (saline)
Description: Intravenous bolus application over 45 seconds

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (saline)
Description: Intravenous bolus application over 45 seconds
Study: NCT06702124

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rotigotine 4Mg/24Hrs Patch
Description: Rotigotine 4 mg/24Hrs administration for 24 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administration for 24 weeks
Study: NCT06698536

Intervention type: DEVICE
Group type: OTHER
Intervention: Aktiia G2C
Description: Study subjects are asked to stay seated while 3 successive measurements are taken with the Aktiia G2C device under investigation (BP and PR) and two references (Aktiia Bracelet G2 and Aktiia Init I1 oscillometric cuff).
Study: NCT06626503

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methadone based ERAS
Description: Children randomized to the methadone arm will receive standardized perioperative care and analgesia, including intraoperative intravenous methadone (0.1 mg/kg up to a maximum of 5 mg before incision and 0.05 mg at the end of surgery) and postoperatively, up to 4 oral doses of methadone every 12 hours before discharge as part of standardized multimodal analgesia in the hospital setting.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SOC non-methadone based group
Description: Children randomized to the standard-of-care arm will receive standard opioid analgesia protocol without intra- and post-operative methadone per the current site standards.
Study: NCT06706817

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tezepelumab
Description: IMP. Subcutaneous injection. Unit dose strengths 210 mg.
Study: NCT06712251

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Velocity pAVF System
Description: The Velocity Percutaneous Arterio-Venous Fistula System consists of a percutaneous method designed to create an arteriovenous fistula for hemodialysis vascular access.
Study: NCT06714552

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Galacto-Oligosaccharide
Description: 24.0 g Oligomate® in 100 mL water

Intervention type: OTHER
Group type: OTHER
Intervention: Glucose
Description: 17.8 g glucose in 100 mL water
Study: NCT06713239

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cleerly Labs and Cleerly ISCHEMIA
Description: Participants in the coronary plaque-based care arm will have CCTA at baseline. CCTA images will be redacted and uploaded to Cleerly, interpreted using Cleerly Labs and Cleerly ISCHEMIA, and archived.
Study: NCT06687967

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Pharmaceutical form: Solution for injection Route of administration: subcutaneous injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form: Solution for injection Route of administration: subcutaneous injection
Study: NCT06718621

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BL-M08D1
Description: Administration by intravenous infusion for a cycle of 3 weeks.
Study: NCT06718348

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Use of the Exoskeleton JAPET.W
Description: Phsysiotherapy sessions with the support of the Exoskeleton JAPET.W
Study: NCT06717750

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CSCJC3456 tablet
Description: * Phase Ia: Single and Multiple Dose Escalation.~  1. Dosage form: tablet.~ 2. Dosage: 7 dose groups, 5 mg, 15 mg, 30 mg, 45 mg, 60 mg, 80 mg, 100 mg.~ 3. Frequency: once daily (tentative), or twice daily and other options (adjusted based on the results of the preliminary trials).~ 4. Duration: 5 mg(days 1-28; 28 days per cycle), other groups (days 1-21; 28 days per cycle) .~* Phase Ib: Cohort Expansion. Dosage and dosing regimen: according to the recommended dosage and dosing cycle from the Phase Ia study.