TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05083481

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP1570
Description: Oral tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pembrolizumab
Description: Intravenous Infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trifluridine + Tipiracil
Description: Oral Administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Intravenous Infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Intravenous Infusion
Study: NCT06556381

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TAP block
Description: Women will receive TAP block.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TAP block
Description: Women will receive TAP block.
Study: NCT06217341

Intervention type: OTHER
Intervention: In the study, bispectral index monitoring and follow-up will be applied to both groups.
Description: Perioperative Bispectral Index Monitoring (BIS) monitor and Bispectral Index suppression Rate (BIS-SR) monitoring will be applied. The duration and magnitude of BIS-SR values will be examined together with BIS values in terms of recovery agitation.

Intervention type: OTHER
Intervention: In the study, bispectral index monitoring and follow-up will be applied to both groups.
Description: Perioperative Bispectral Index Monitoring (BIS) monitor and Bispectral Index suppression Rate (BIS-SR) monitoring will be applied. The duration and magnitude of BIS-SR values will be examined together with BIS values in terms of recovery agitation.
Study: NCT03473483

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SREC
Description: The Standardized Research E-Cigarette (SREC) was developed by NIDA to help researchers assess uncertainties in electronic nicotine delivery devices.~Tank:~* Sealed and disposable~* Minimum 350 puffs per tank~* Volume of e-liquid per tank \~ 3ml~E-Liquid Characteristics:~* Tobacco flavored~* Nicotine concentration: 15 mg/ml~* Propylene Glycol:\~ 50% (wt / wt)~* Glycerin: \~ 50% (wt / wt)~* Cotinine: \<1 μg/g~* Nornicotine: 5 μg/g~* Myosmine : 3 μg/g~* Anabasine: \<1 μg/g~* Anatabine: \<1 μg/g~* Beta:nicotyrine: \<1 μg/g~* Diacetyl: \<2 μg/g~* 2,3:Pentanedione: \<1 μg/g~* Arsenic: \<0.1 μg/g~* Cadmium: \<0.1 μg/g~* Chromium: \<0.1 μg/g~* Lead: \<0.1 μg/g~* Nickel: \<0.1 μg/g~* Mercury: \<0.05 μg/g
Study: NCT06630767

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ERAS
Description: Enhanced recovery after surgery (ERAS) programs are a combination of evidenced-based perioperative care approaches that work synergistically to improve recovery after surgery. The core elements of ERAS protocols are preoperative advice, optimization of diet, systematic analgesic and anesthetic regimes, and early mobilization.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional
Description: Conventional care for patients subjected for laparoscopic common bile duct exploration
Study: NCT06694948

Intervention type: DRUG
Group type: OTHER
Intervention: pimicotinib capsules
Description: pimicotinib capsules

Intervention type: DRUG
Group type: OTHER
Intervention: pimicotinib capsules
Description: pimicotinib capsules
Study: NCT06634069

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Lactate
Description: 0.5M HSL (containing 504mM of sodium and lactate)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 3% NaCl
Description: active compartor 3% NaCl
Study: NCT06420336

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus lumborum block
Description: After induction of anesthesia and securement of appropriate airway device, the patient will be placed in position for the QL block. Using ultrasound guidance, the pediatric anesthesiology attending will perform unilateral QL block on the side of the anterior iliac bone graft harvest. The dose will be 0.2% ropivacaine, 1 mL per kilogram to a max of 20 mL with an additive of dexamethasone 4 mg. Ultrasonography will be used to identify external oblique, internal oblique, transverse abdominus and quadratus lumborum muscles. A 50 mm-150 mm block needle will be advanced under ultrasound guidance. Ropivacaine will be injected slowly with frequent aspiration to rule out incorrect needle placement. The anesthetic is deposited at the lateral edge of the QL after penetrating the transversus abdominus aponeurosis. Injection will continue to be observed with real time US guidance.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthetic infiltration
Description: After induction of anesthesia and securement of appropriate airway device the patient will be turned over to the surgical team to proceed with the operation. The surgeon will proceed with usual injection of local anesthetic as their standard of care; this medication will be charted by the circulating nurse in the Medication Administration Record with local anesthetic type and amount. At the conclusion of the procedure, to maintain the blind, the patient will have a bandage placed where the QL block would have been performed.
Study: NCT06702553

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitric Oxide Gas
Description: Patients will receive 80 parts per million (ppm) NO during CPB through the oxygenator. After weaning of CPB, test gases will be delivered via inspiration limb of ventilator at a dose range of 40-80 ppm until 6 hours after ICU admission or until extubation after surgery, whichever comes first.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Standard Care Arm
Description: Patients in this group will receive standard care and 80 ppm nitrogen (N2, control group) are added to the gas mixture as control. In the circumstances when the N2 is not applicable, such as when the plasma-chemical NO synthesis device is employed for NO generatiaon and delivery, the device will be connected to the CPB and ventilator circuits, but the synthesis will remain inactive in the control group. Consequently, the circuit will be supplied with air devoid of NO.
Study: NCT06725706

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-92/AV45, 11C-PIB
Description: Each subject receive a single intravenous injection of 18F-92/AV45, 11C-PIB and undergo PET/CT or MRI imaging within the specificed time.
Study: NCT06746935

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Collagen membrane.
Description: Particulate bone mixture 1:1 autogenous and xenogenic bone covered with native collagen membrane.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Polytetrafluoroethylene membrane.
Description: Particulate bone mixture 1:1 autogenous and xenogenic bone covered with polytetrafluoroethylene membrane.
Study: NCT06748144

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraosseous Vancomycin
Description: The intervention is specific to the method of administration that will be used when giving the dose of antibiotic vancomycin which is done to prevent infection following surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous Vancomycin
Description: This is the standard method of giving the antibiotic vancomycin to patients undergoing surgery across many specialties in order to prevent infection.
Study: NCT06750172

Intervention type: DIAGNOSTIC_TEST
Intervention: The oral sodium loading test
Description: The subjects underwent an oral high-salt diet test with an additional 10g of salt per day for 3 consecutive days, and 24-hour urine measurements of aldosterone, sodium, potassium and creatinine were obtained on days 2 and 3

Intervention type: DIAGNOSTIC_TEST
Intervention: The oral sodium loading test
Description: The subjects underwent an oral high-salt diet test with an additional 10g of salt per day for 3 consecutive days, and 24-hour urine measurements of aldosterone, sodium, potassium and creatinine were obtained on days 2 and 3
Study: NCT06751433

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Scar gel
Description: Health care product (scar gel)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Scar gel comparator
Description: Health care product (Scar gel comparator)
Study: NCT06749574

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: stability ball exercises
Description: to enhance balance, core stability, They were introduced to the stability ball with instructions on maintaining proper posture, alignment, and safety to prevent injuries. The program included exercises such as the seated march, where participants lifted each leg alternately while seated on the ball, ensuring the ball remained stable. Wall squats were also performed with the ball positioned between the lower back and a wall, allowing participants to strengthen their lower body while maintaining control. Additionally, pelvic tilts were included to activate the lower abdominal muscles and glutes through gentle, controlled movements.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: dead bug exercise
Description: Participants performed exercises such as extending one arm and the opposite leg while lying on their backs, ensuring their spine remained neutral and their lower back stayed pressed into the floor. Variations included alternating opposite arm and leg movements and holding the extended position for two seconds to increase the challenge and enhance core stability. These exercises were performed slowly to maintain control and improve movement precision over the eight-week period.
Study: NCT06750835

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SPSIP block
Description: Serratus posterior superior intercostal plane block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SAP block
Description: Serratus anterior plane block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Paravertebral block
Description: * The block will be administered under ultrasound guidance at the T2-T5 levels.~* A total of 15 mL of 0.25% bupivacaine will be injected into the paravertebral space on the side of the surgery.
Study: NCT06748586

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hyperbaric Oxygen Therapy
Description: The HBOT protocol is 90 minutes, 5 times/week, for at least 40 sessions, 100% oxygen at 2 ATA with five-minute air breaks every 20 minutes. Investigational product: Multiplace hyperbaric oxygen chamber (Haux Starmed 2700, Germany) located at the Sagol center for hyperbaric medicine and research, Shamir (Assaf-Harofeh) Medical Center, Israel.
Study: NCT06748560

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurodynamics
Description: Following Castellote-Caballero et al., the neurodynamic sliding technique (NST) was applied to the dominant leg's sciatic nerve in the NST and ETNST groups. The technique involves alternating stress proximally and distally to promote nerve sliding. Participants performed two sets of movements-cervical flexion with knee and ankle flexion, and cervical extension with knee and ankle extension-repeated actively for 60 seconds, five times per session. Over six weeks, both groups underwent three supervised sessions per week led by an experienced researcher.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neurodynamics
Description: Following Castellote-Caballero et al., the neurodynamic sliding technique (NST) was applied to the dominant leg's sciatic nerve in the NST and ETNST groups. The technique involves alternating stress proximally and distally to promote nerve sliding. Participants performed two sets of movements-cervical flexion with knee and ankle flexion, and cervical extension with knee and ankle extension-repeated actively for 60 seconds, five times per session. Over six weeks, both groups underwent three supervised sessions per week led by an experienced researcher.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Eccentric training
Description: The Nordic exercise served as the foundation for the intervention, focusing on eccentric loading as participants resisted falling forward. To minimize DOMS and ensure adherence, a two-week preparatory phase of mixed concentric/eccentric leg curls using a stability ball was implemented. Following this, the gradual progression outlined by Mjolsnes et al. led to a four-week Nordic hamstring curl regimen. Weekly supervision ensured proper technique and compliance throughout the program.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eccentric training
Description: The Nordic exercise served as the foundation for the intervention, focusing on eccentric loading as participants resisted falling forward. To minimize DOMS and ensure adherence, a two-week preparatory phase of mixed concentric/eccentric leg curls using a stability ball was implemented. Following this, the gradual progression outlined by Mjolsnes et al. led to a four-week Nordic hamstring curl regimen. Weekly supervision ensured proper technique and compliance throughout the program.
Study: NCT06749743

Intervention type: DIAGNOSTIC_TEST
Intervention: FASTER RCNN
Description: train artificial intelligence models ( FASTER RCNN, YOLOY ) to detect dental caries , then test their accuracy
Study: NCT03473483

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SREC
Description: The Standardized Research E-Cigarette (SREC) was developed by NIDA to help researchers assess uncertainties in electronic nicotine delivery devices.~Tank:~* Sealed and disposable~* Minimum 350 puffs per tank~* Volume of e-liquid per tank \~ 3ml~E-Liquid Characteristics:~* Tobacco flavored~* Nicotine concentration: 15 mg/ml~* Propylene Glycol:\~ 50% (wt / wt)~* Glycerin: \~ 50% (wt / wt)~* Cotinine: \<1 μg/g~* Nornicotine: 5 μg/g~* Myosmine : 3 μg/g~* Anabasine: \<1 μg/g~* Anatabine: \<1 μg/g~* Beta:nicotyrine: \<1 μg/g~* Diacetyl: \<2 μg/g~* 2,3:Pentanedione: \<1 μg/g~* Arsenic: \<0.1 μg/g~* Cadmium: \<0.1 μg/g~* Chromium: \<0.1 μg/g~* Lead: \<0.1 μg/g~* Nickel: \<0.1 μg/g~* Mercury: \<0.05 μg/g

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SREC
Description: The Standardized Research E-Cigarette (SREC) was developed by NIDA to help researchers assess uncertainties in electronic nicotine delivery devices.~Tank:~* Sealed and disposable~* Minimum 350 puffs per tank~* Volume of e-liquid per tank \~ 3ml~E-Liquid Characteristics:~* Tobacco flavored~* Nicotine concentration: 15 mg/ml~* Propylene Glycol:\~ 50% (wt / wt)~* Glycerin: \~ 50% (wt / wt)~* Cotinine: \<1 μg/g~* Nornicotine: 5 μg/g~* Myosmine : 3 μg/g~* Anabasine: \<1 μg/g~* Anatabine: \<1 μg/g~* Beta:nicotyrine: \<1 μg/g~* Diacetyl: \<2 μg/g~* 2,3:Pentanedione: \<1 μg/g~* Arsenic: \<0.1 μg/g~* Cadmium: \<0.1 μg/g~* Chromium: \<0.1 μg/g~* Lead: \<0.1 μg/g~* Nickel: \<0.1 μg/g~* Mercury: \<0.05 μg/g
Study: NCT06748105

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin (DAPA)
Description: Participants will receive 10mg/day of dapagliflozin orally. The administration will occur within a synchronous range, meaning that the time difference between dapagliflozin administration and glucocorticoid administration should not exceed 12 hours.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin (DAPA)
Description: Participants will receive 10mg/day of dapagliflozin orally. The administration will occur within a synchronous range, meaning that the time difference between dapagliflozin administration and glucocorticoid administration should not exceed 12 hours.
Study: NCT06748820

Intervention type: BEHAVIORAL
Intervention: Remote Therapeutic Patient Education (e-TPE)
Description: TPE is a set of practices aiming at allowing a patient to acquire and preserve abilities and skills to manage actively their disease, cares, and surveillance, in collaboration with the caregivers
Study: NCT06748326

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Laparoscopy
Description: Intussusception reduction by laparoscopy in children in failed non surgical procedures and in recurrence
Study: NCT06022887

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TRE
Description: daily ad libitum food intake, 8-h 12pm - 8pm, 8 wks active weight loss phase;

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TRE
Description: daily ad libitum food intake, 8-h 12pm - 8pm, 8 wks active weight loss phase;

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MBSR
Description: Completed 30 sessions of a Mindfulness-Based Stress Reduction (MBSR) interventions for 8 weeks

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MBSR
Description: Completed 30 sessions of a Mindfulness-Based Stress Reduction (MBSR) interventions for 8 weeks
Study: NCT04434729

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils
Description: The study involves a single fetal intervention of maternal transuterine, fetal transcranial torcular puncture and median prosencephalic vein embolization. Detachable platinum coils (Target XL and XXL Detachable Coil, Stryker Neurovascular) will be used to pack the prosencephalic varix.
Study: NCT05432167

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIN-107
Description: Patients will take CIN-107 tablets by mouth once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CIN-107
Description: Patients will take CIN-107 tablets by mouth once daily.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will take placebo tablets by mouth once daily.
Study: NCT04268277

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: 100 mg concentrate for solution for infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 100 mg/ 4mL concentrate for solution for infusion
Study: NCT05293717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: 1.5% Ruxolitinib cream
Study: NCT04129450

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group medical visits with mindfulness-based stress reduction
Description: Eight weekly 90 minute sessions of mindfulness-based stress reduction in group medical visits

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual PCP care
Description: Usual one on one PCP care for chronic lower back pain

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual PCP care
Description: Usual one on one PCP care for chronic lower back pain
Study: NCT06275022

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Inflow occlusion with perforation of septation and sclerotherapy
Description: Inflow occlusion assisted by indocyanine green-fluorescence imaging combined with perforation of septation and sclerotherapy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Perforation of septation and sclerotherapy
Description: Perforation of septation and sclerotherapy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Indocyanine green-guided partial resection and sclerotherapy
Description: Indocyanine green-fluorescence imaging-guided partial resection and sclerotherapy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Partial resection and sclerotherapy
Description: Partial resection and sclerotherapy
Study: NCT05523973

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lingual Endurance Exercise
Description: Participants will participate in 3 training sessions per day for 8 weeks. Group 1 will complete 3 sessions of lingual endurance exercise. For example, if the participant completed 100 repetitions during the baseline measurement, they would complete 75 repetitions during their exercise session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lingual Endurance Exercise
Description: Participants will participate in 3 training sessions per day for 8 weeks. Group 1 will complete 3 sessions of lingual endurance exercise. For example, if the participant completed 100 repetitions during the baseline measurement, they would complete 75 repetitions during their exercise session.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transference Group
Description: Group 2 will complete lingual endurance exercise for 2 sessions, and for the 3rd training session participants will complete 30 swallows where they are instructed to press their tongue hard on the bulb and swallow their saliva.
Study: NCT05948709

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Incentives for Physical Activity
Description: Participants earn a meal donation and monetary incentives for each day that they reach 7,500 steps. Meals are donated by the investigators on behalf of participants.
Study: NCT06361160

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Transcranial Magnetic Stimulation (TMS)
Description: Active rTMS (continuous theta burst, cTBS) applied to the temporo-parietal junction (TPJ) at the onset of the Auditory Verbal Hallucinations (AVH).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Transcranial Magnetic Stimulation (TMS)
Description: Sham rTMS (continuous theta burst, cTBS) applied to the temporo-parietal junction (TPJ) during the onset of the Auditory Verbal Hallucinations (AVH).~An electrical stimulator is synchronised with the magnetic stimulation to recreate the tactile sensation and the coils emits the same noise during sham stimulation as in the active configuration, making it impossible to distinguish between active and placebo magnetic stimulation.