TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06602635

Intervention type: DIAGNOSTIC_TEST
Intervention: ECG and clinical score
Description: The Hybrid Score (HS), detailed in previous literature involves a sum of points based on clinical and ECG characteristics. Points are assigned as follows: one point each for being over 50 years old, male, and having arterial hypertension. ECG-based points are allocated according to QRS transition: 3 points for a transition in V1, 2 points for V2, 1 point for V3 if the R-wave in V3 is greater than 1 mV; 1 point is subtracted if V3 has an R-wave less than 1 mV, and further deductions or additions apply for transitions up to V6. A score ≤ 1 suggests an RVOT origin, whereas ≥ 2 suggests an LVOT origin.

Intervention type: DIAGNOSTIC_TEST
Intervention: ECG and clinical score
Description: The Hybrid Score (HS), detailed in previous literature involves a sum of points based on clinical and ECG characteristics. Points are assigned as follows: one point each for being over 50 years old, male, and having arterial hypertension. ECG-based points are allocated according to QRS transition: 3 points for a transition in V1, 2 points for V2, 1 point for V3 if the R-wave in V3 is greater than 1 mV; 1 point is subtracted if V3 has an R-wave less than 1 mV, and further deductions or additions apply for transitions up to V6. A score ≤ 1 suggests an RVOT origin, whereas ≥ 2 suggests an LVOT origin.
Study: NCT06609733

Intervention type: DEVICE
Intervention: Twin block
Description: The TB group used a single appliance continuously, with appropriate reduction of occlusal surface height by 1 mm when clinically indicated. Both groups had follow-up appointments every 6 weeks.

Intervention type: DEVICE
Intervention: Clear aligner with mandibular function
Description: The MA group underwent stepwise mandibular forward movement with clear aligners (Invisalign, Align Inc, CA, USA) worn for 22 hours/day and replaced every 7 days.
Study: NCT06610565

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: FASTING-MIMICKING DIET PROGRAM
Description: Nutritional intervention via fasting-mimicking diet. Patients receiving adjuvant therapy with aromatase inhibitors will be randomized 1:1 into two arms: one intervention, where will receive nutritional counseling and the study diet for 5 days each month for 6 months,and a control one, where they will receive only nutritional counseling.
Study: NCT05581563

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: total knee arthroplasty(TKA)
Description: Knee replacement, also called knee arthroplasty or total knee replacement, is a surgical procedure to resurface a knee damaged by arthritis. Metal and plastic parts are used to cap the ends of the bones that form the knee joint, along with the kneecap. This surgery may be considered for someone who has severe arthritis or a severe knee injury.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: total knee arthroplasty(TKA)
Description: Knee replacement, also called knee arthroplasty or total knee replacement, is a surgical procedure to resurface a knee damaged by arthritis. Metal and plastic parts are used to cap the ends of the bones that form the knee joint, along with the kneecap. This surgery may be considered for someone who has severe arthritis or a severe knee injury.
Study: NCT01531634

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic Cognitive Intervention Group
Description: Twelve meetings of a Dynamic Cognitive Intervention group.
Study: NCT06609395

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief online CBT targeting excessiv worry
Description: The intervention with a focus on excessive worry lasted five weeks and was delivered through five online modules with therapist support. Modules covered psychoeducation, problem-solving, reducing excessive media consumption, detached mindfulness, and shifting focus from worry. The final module offered relapse prevention strategies.
Study: NCT06610305

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal estradiol
Description: 0.1 mg/day delivered via weekly patch

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal estradiol
Description: 0.1 mg/day delivered via weekly patch
Study: NCT04507113

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DTI sequence acquisition
Description: DTI sequence acquisition
Study: NCT05392400

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Steri3X
Description: This study will initially attempt to recruit pregnant patients at the Regional One Health outpatient obstetrics clinic, at which point they will be randomly assigned to one of two cohorts. Participants who are consented to participate in the study will receive a chart flag in the EMR so that they may receive the proper intraoperative and postoperative treatment(s). Patients randomized to receive the Steri3X wound dressing will have the liquid polymer applied in the operating room after closure of the Cesarean section incision. Participants of both arms will be monitored postoperatively to assess for signs and symptoms of postoperative surgical site infection(s).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Device: Steri3X~This study will initially attempt to recruit pregnant patients at the Regional One Health outpatient obstetrics clinic, at which point they will be randomly assigned to one of two cohorts. Participants who are consented to participate in the study will receive a chart flag in the EMR so that they may receive the proper intraoperative and postoperative treatment(s). Patients randomized to receive the control wound dressing will have the current standard of care dressing applied in the operating room after closure of the Cesarean section incision. Participants of both arms will be monitored postoperatively to assess for signs and symptoms of postoperative surgical site infection(s).
Study: NCT06521242

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient Education
Description: The intervention group was given 120 minutes of training.
Study: NCT06480708

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic diet
Description: The ketogenic diet consisting of fats (70%), protein (20%) and carbohydrates (10%) will be consumed for 14 days prior to undergoing open-heart surgery, and up to 6 days postoperatively or until discharge (if within 6 days postoperatively).
Study: NCT06610305

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Progesterone
Description: 100 mg twice daily (200 mg/day total) administered via oral capsule
Study: NCT05982990

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ADVAIR DISKUS® 250/50
Description: 2 inhalations in one study period
Study: NCT06610305

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Progesterone
Description: 100 mg twice daily (200 mg/day total) administered via oral capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal placebo patch
Description: Once weekly via transdermal patch

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal placebo patch
Description: Once weekly via transdermal patch

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo capsule
Description: Twice daily via oral capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo capsule
Description: Twice daily via oral capsule
Study: NCT06609551

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6-month adjuvant chemotherapy with 5-FU monotherapy
Description: 6 months of adjuvant chemotherapy with 5-FU monotherapy. The follow-up strategy for the four groups of subjects will be the same, including but not limited to chest plain or enhanced CT, abdominal/pelvic enhanced CT, and detection of the tumor marker carcinoembryonic antigen (CEA), until disease progression occurs. All patients will undergo peripheral blood ctDNA-MRD testing again six months after surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6-month adjuvant chemotherapy with 5-FU monotherapy
Description: 6 months of adjuvant chemotherapy with 5-FU monotherapy. The follow-up strategy for the four groups of subjects will be the same, including but not limited to chest plain or enhanced CT, abdominal/pelvic enhanced CT, and detection of the tumor marker carcinoembryonic antigen (CEA), until disease progression occurs. All patients will undergo peripheral blood ctDNA-MRD testing again six months after surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XELOX intensive treatment group
Description: XELOX intensive treatment group. The follow-up strategy for the four groups of subjects will be the same, including but not limited to chest plain or enhanced CT, abdominal/pelvic enhanced CT, and detection of the tumor marker carcinoembryonic antigen (CEA), until disease progression occurs. All patients will undergo peripheral blood ctDNA-MRD testing again six months after surgery.
Study: NCT06609954

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reduced Exertion High Intensity Training (REHIT)
Description: Participant will perform a 5 min warm-up exercises then do cycling or treadmill running for 20 min at 40%-60% of HRR and then will conclude with 5 min cool down exercises. From week 2 to 6 participants will be instructed to perform training sessions on a cycle ergometer. Each session will consist of a 3-minute warm-up period followed by two 20-second all-out sprints interspersed with 3 minutes of slow pedaling for recovery. Total of 18 sessions of REHIT will be performed thrice a week on alternate days by the participants for consecutive 6 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training (HIIT)
Description: Patients in this group will be provided with a caloric restriction plan by a nutritionist that will be followed throughout the training duration. Week 1 will be baseline fitness level and familiarization week. Participant will perform a 5 min warm-up exercises then do cycling or treadmill running for 20 min at 40%-60% of HRR and then will conclude with 5 min cool down exercises. From week 2 to 6 participants will be instructed to perform a warm up of 5 min, then 4 bouts of 4 min of HIIT will be performed at 80%-95% of HRR separated by 3-min active recovery periods of moderate intensity cycling at 60%-70% of the HRR followed by 5 min cool down exercises. Pre and post session vitals will be noted. Total of 18 sessions of either HIIT will be performed thrice a week on alternate days by the participants for consecutive 6 weeks.
Study: NCT06610006

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High Intensity Interval Training (HIIT)
Description: High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period..A total of 15 sessions of high intensity interval training alone , for thrice a week on alternative days for 5 consecutive weeks will be given. Warm-up session consisting of stretching exercises prior to intervention and cool down session after intervention will also be done and vitals before and after the session will be taken.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training (HIIT)
Description: High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period..A total of 15 sessions of high intensity interval training alone , for thrice a week on alternative days for 5 consecutive weeks will be given. Warm-up session consisting of stretching exercises prior to intervention and cool down session after intervention will also be done and vitals before and after the session will be taken.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Isometric Wall Squat
Description: For isometric wall squat, each training session will be composed of 4 × 2-min bouts of IWS followed by 2-min rest periods. In first week, participants will do squat training or there will be a protocol for selecting exercise intensity in which participants will be given 30-s to perform a wall squat to select a position that they predict would elicit an target RPE score by varying the squat height. Based on the final squat height and RPE score, after bout 4, participants will be given a starting squat height for training session 1 and will then be progressed in each week
Study: NCT05172609

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exposure Based Implementation Strategy (EBIS)
Description: EBIS will include psychoeducation, assessment/hierarchy building. guided practice, and guidance for application to clinical practice.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Implementation as Usual (IAU)
Description: IAU will consist of standard didactic training and ongoing consultation activities for enrolled clinicians
Study: NCT05931926

Intervention type: DEVICE
Intervention: Fluispotter®
Description: The Fluispotter® has been developed for automated extraction, collection and storage of up to 20 dried venous dried blood spot samples of 3-10 μl over the course of up to 20 hours. The system is attached to the patient through a multilumen microcatheter inserted into a peripheral vein in the arm. The Fluispotter will be inserted in both healthy subjects and patients with adrenal insufficiency.

Intervention type: DEVICE
Intervention: Fluispotter®
Description: The Fluispotter® has been developed for automated extraction, collection and storage of up to 20 dried venous dried blood spot samples of 3-10 μl over the course of up to 20 hours. The system is attached to the patient through a multilumen microcatheter inserted into a peripheral vein in the arm. The Fluispotter will be inserted in both healthy subjects and patients with adrenal insufficiency.
Study: NCT06115616

Intervention type: BEHAVIORAL
Intervention: Morning exercise
Description: Exercise before noon in the morning

Intervention type: BEHAVIORAL
Intervention: Afternoon exercise
Description: Exercise in the late after noon
Study: NCT06480708

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control diet
Description: The control diet consisting of a Mediterranean diet, at 25% fat, 20% protein and 55% carbohydrates will be consumed for 14 days prior to undergoing open-heart surgery, and up to 6 days postoperatively or until discharge (if within 6 days postoperatively).
Study: NCT04890379

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dimethyl fumarate
Description: Dimethyl fumarate 240mg orally twice daily for 3 consecutive days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 240mg orally twice daily for 3 consecutive days
Study: NCT06313164

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: enhanced glutathione
Description: L-glutathione (in combination with tannin, low molecular weight chitosan and polyethylene glycol)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo comparator
Description: placebo group
Study: NCT06001346

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ActiveCBT
Description: Participants will complete a standardized 30-minute aerobic exercise session on a stationary bicycle prior to therapy. Supervised exercise sessions will consist of steady-state exercise at a moderate intensity corresponding to a '13' or 'somewhat hard' rating of perceived exertion. Continuous monitoring of heart rate, resistance/load, and RPE will occur throughout exercise. To closely match the groups, participants will also view 30-minute nature videos while exercising.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CalmCBT
Description: Participants will view one of 8 standardized 30-minute nature videos while resting quietly prior to therapy. These are emotionally neutral videos and will allow for participants in both groups to have the same amount of attention and contact time.
Study: NCT06611332

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: The main acupoints selected for the electroacupuncture group are bilateral BL23, bilateral BL25, bilateral GB30, bilateral LR11, bilateral LR8, GV4, GV3, and the affected BL40, and the secondary acupoints selected are bilateral BL54, the affected side BL57 and the affected side BL60.The treatment will be administered once every other day for 30 minutes each time, lasting for 8 consecutive weeks, totaling 24 sessions.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham electroacupuncture
Description: In the sham electroacupuncture group, the acupoints will be at a position 2 cm lateral to the correct acupoints horizontally. The dosage and treatment course are the same as those in the electroacupuncture group.
Study: NCT05559476

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSVPreF3 OA investigational vaccine
Description: RSVPreF3 OA investigational vaccine administered intramuscularly in the deltoid region of the non-dominant arm.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: RSVPreF3 OA investigational vaccine
Description: RSVPreF3 OA investigational vaccine administered intramuscularly in the deltoid region of the non-dominant arm.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FLU HD vaccine
Description: FLU HD vaccine administered intramuscularly in the deltoid region of the dominant arm (Co-Ad Group) or the non-dominant arm (Control Group).
Study: NCT04935073

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prescription of traditional Chinese Medicine named Er Zhi Wan combined with Si Wu Tang
Description: The medicines used in this study including Radix et Rhizoma Ligustrum 15 g, Radix Morindae Sinensis 12 g, Fructus Lycii 15 g, Semen Cuscutae 20 g, Radix Rehmanniae 15 g, Radix Angelicae Sinensis 10 g, Radix Paeoniae Alba 10 g, Ligusticum wallichii 6 g, Poria cocos 15g, Polygonatum 15g, eclipta 10g. which will be taken for 10-15days.After the ET, the treatment group will continue to take Chinese herbal medicine, changing to Shou Tai pills ( Morinda officinalis 15 g, Teasel 15g，Cuscutae 20 g, Eucommia ulmoides 15 g, Rehmannia 15 g, Cornus officinalis 15 g, loranthus parasiticus 20 g, Ligustrum lucidum 15g, Salvia miltiorrhiza 10g, Scutellaria baicalensis 10g, Atractylodes macrocephala 15g); which will be taken for 14days. The hospital will be responsible for the decoction of 200 mL per dose, 1 dose per day, divided into 2 doses in the morning and in the evening.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human Follitropin Alfa for Injection、Fructose Injection、Tetyacycline Hydrochloride Capsules、Cetrorelix Acetate Powder for Injection
Description: The intervention starts from the 5th day of the menstrual cycle and lasts to the day before IVF-ET.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Recombinant Human Follitropin Alfa for Injection、Fructose Injection、Tetyacycline Hydrochloride Capsules、Cetrorelix Acetate Powder for Injection
Description: The intervention starts from the 5th day of the menstrual cycle and lasts to the day before IVF-ET.
Study: NCT05415358

Intervention type: OTHER
Intervention: Blood and tissue samples
Description: Blood and tissue will be collected to perform ctDNA and immune biomarkers assessment to predict progression within 6 months of pembrolizumab discontinuation.
Study: NCT05559476

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: FLU HD vaccine
Description: FLU HD vaccine administered intramuscularly in the deltoid region of the dominant arm (Co-Ad Group) or the non-dominant arm (Control Group).
Study: NCT05576753

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hernia repair
Description: Robot assisted laparoscopic preperitoneal repair (vTAPP: ventral transabdominal preperitoneal hernia repair) of a midline ventral hernia
Study: NCT06502496

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: art-therapy
Description: Over the 6 sessions, different artistic techniques will be explored, depending on the artist leading the workshop: stencil, graffiti, spray paint, collage, oil pastel, calligraphy and acrylic doodling. A collective work may also be proposed.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: relaxation
Description: relaxation sessions with the referent psychologist
Study: NCT06117865

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 1
Description: Module 1: Introduction to IBS by a gastroenterologist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 1
Description: Module 1: Introduction to IBS by a gastroenterologist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 1
Description: Module 1: Introduction to IBS by a gastroenterologist.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Module 1
Description: Module 1: Introduction to IBS by a gastroenterologist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 2
Description: Module 2:Introduction to pain physiology and how the nervous system works by a physiotherapist including practical exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 2
Description: Module 2:Introduction to pain physiology and how the nervous system works by a physiotherapist including practical exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 2
Description: Module 2:Introduction to pain physiology and how the nervous system works by a physiotherapist including practical exercises.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Module 2
Description: Module 2:Introduction to pain physiology and how the nervous system works by a physiotherapist including practical exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 3
Description: Module 3: Evidence-based guidelines for diet and lifestyle advice (NICE Guidelines) by a clinical dietitian.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 3
Description: Module 3: Evidence-based guidelines for diet and lifestyle advice (NICE Guidelines) by a clinical dietitian.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 3
Description: Module 3: Evidence-based guidelines for diet and lifestyle advice (NICE Guidelines) by a clinical dietitian.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Module 3
Description: Module 3: Evidence-based guidelines for diet and lifestyle advice (NICE Guidelines) by a clinical dietitian.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 4
Description: Module 4: Intervention: behavioral therapy (exposure therapy and cognitive behavioral therapy).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 4
Description: Module 4: Intervention: behavioral therapy (exposure therapy and cognitive behavioral therapy).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 5
Description: Module 5: Intervention: The low FODMAP diet.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Module 5
Description: Module 5: Intervention: The low FODMAP diet.