TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05373108

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Macitentan
Description: Macitentan is a nonselective endothelin-receptor antagonist (ERA) that is approved for use in pulmonary arterial hypertension (PAH); the use of Macitentan in post-heart transplant patients is considered investigational.
Study: NCT06534580

Intervention type: DEVICE
Intervention: Virtual Reality
Description: A range of virtual reality software, delivered through the DR.VR (TM) device.

Intervention type: DEVICE
Intervention: Virtual Reality
Description: A range of virtual reality software, delivered through the DR.VR (TM) device.
Study: NCT06308991

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yakson touch
Description: Yakson touch method will be started 5 minutes before the endotracheal aspiration procedure and continued until the completion of the procedure.The Yakson method continued for 15 minutes with steady touch (5 minutes), compassionate caressing (5 minutes), and repetition of steady touch (5 minutes).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gentle Human Touch
Description: Gentle Human Touch (GHT) method will be started 5 minutes before the endotracheal aspiration procedure and continued until the completion of the procedure.The GHT method continued for 15 minutes.

Intervention type: OTHER
Group type: OTHER
Intervention: Routine care
Description: Infants in the Routine care will be applied swaddling. It will be started 5 minutes before the endotracheal aspiration procedure and continued until the completion of the procedure.
Study: NCT05894681

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: THE EFFECT OF WATSON MODEL-BASED PSYCOEDUCATIONAL INTERVENTIONS ON PREVENTION OF POSTPARTITION DEPRESS
Description: THE EFFECT OF WATSON MODEL-BASED PSYCOEDUCATIONAL INTERVENTIONS ON PREVENTION OF POSTPARTITION DEPRESS

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: THE EFFECT OF WATSON MODEL-BASED PSYCOEDUCATIONAL INTERVENTIONS ON PREVENTION OF POSTPARTITION DEPRESS
Description: THE EFFECT OF WATSON MODEL-BASED PSYCOEDUCATIONAL INTERVENTIONS ON PREVENTION OF POSTPARTITION DEPRESS
Study: NCT05943912

Intervention type: OTHER
Intervention: Single Vision Spectacle Lens
Description: 36 months of therapy

Intervention type: OTHER
Intervention: Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens
Description: 36 months of therapy
Study: NCT06276959

Intervention type: DIAGNOSTIC_TEST
Intervention: intraoral scanning
Description: The patients underwent intraoral scanning using an iTero Element 5D imaging system (Align Technology, San Jose, CA, USA). This imaging system uses near-infrared light with a wavelength of 850 nm and provides multiple layers of data in a single scan, including a three-dimensional (3D) model, two-dimensional (2D) color images, and NIRI mapped to the 3D model

Intervention type: DIAGNOSTIC_TEST
Intervention: clinical oral examination
Description: Under illumination in the dental unit, a UVE of the proximal surfaces of the patient's entire dentition was conducted by clinicians using a mouth mirror, dental probe, and an air-water syringe. Visual and tactile methods were performed according to the guidelines of the American Dental Association. Clinicians assessed the soundness of the proximal surfaces based on the presence of discoloration, surface alterations, or cavitation.

Intervention type: DIAGNOSTIC_TEST
Intervention: cone-beam computed tomography
Description: All enrolled patients underwent CBCT scans because clear aligner treatment required real root/bone visualization features. We would like to clarify that due to the retrospective cross-sectional nature of this study, the patients involved were not subjected to radiation beyond what was initially necessary for their orthodontic treatment.
Study: NCT05083988

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality glasses
Description: a system composed of a head-mounted wide view display placed in front of the eyes and headphones placed in ears, it has the ability to block the real-world stimuli. This could distract the patient from the dental environment, which helps reduce anxiety

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: music
Description: Music can be used to distract patients from the anxiety provoking stimulus. It helps the patient to escape from the stressful reality as it activates imaginary. Psychosocially music can offer peace and comfort to patients during dental treatment as it helps in making the environment less threatening.
Study: NCT05898971

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Robotic
Description: Patients receive robotic training (grasp and grip)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror
Description: Patients receive mirror therapy
Study: NCT05300256

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Peripheral Heating
Description: Peripheral heating of the feet

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: Sham
Study: NCT06573034

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Daoist Zhanzhuang
Description: Each session of practice will last 30 minutes, and participants are expected to participate every day for 3 months. During the initial 3 weeks, participants will engage in in-person sessions 3 times a week. On non-session days, they can choose to either attend a Zoom practice session with the coach or submit a recording of their individual practice for fidelity check. In Week 4, participants will attend an in-person session for both practice and assessment. Over the subsequent 8 weeks, participants will either attend in-person or Zoom sessions, with a total of 3 check-in sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sham Wall Squat
Description: Same as the Zhanzhuang group.
Study: NCT04120402

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EP-104IAR 25 mg
Description: Single 5 mL intra-articular injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: Single 5 mL intra-articular injection
Study: NCT05108818

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Seasonal influenza vaccine
Description: The seasonal influenza vaccine is administered intramuscularly at a dose of 15 ug of HA per component, as approved by the FDA.
Study: NCT05937646

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AWARE
Description: AWARE is a platform with a visualization dashboard that sits on top of pre-existing, comprehensive EHR systems. AWARE provides clinical decision support tools for the ICU, Emergency Departments and other critical care areas right at the patient's bedside.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AWARE
Description: AWARE is a platform with a visualization dashboard that sits on top of pre-existing, comprehensive EHR systems. AWARE provides clinical decision support tools for the ICU, Emergency Departments and other critical care areas right at the patient's bedside.
Study: NCT04756986

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: malic acid
Description: 1% malic acid spray
Study: NCT05937646

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electronic Health Record (EHR)
Description: An Electronic Health Record (EHR) is an electronic version of a patients medical history, that is maintained by the provider over time, and may include all of the key administrative clinical data relevant to that persons care under a particular provider, including demographics, progress notes, problems, medications, vital signs, past medical history, immunizations, laboratory data and radiology reports.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electronic Health Record (EHR)
Description: An Electronic Health Record (EHR) is an electronic version of a patients medical history, that is maintained by the provider over time, and may include all of the key administrative clinical data relevant to that persons care under a particular provider, including demographics, progress notes, problems, medications, vital signs, past medical history, immunizations, laboratory data and radiology reports.
Study: NCT06333613

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D)
Description: Test Lens
Study: NCT05874921

Intervention type: DRUG
Intervention: Jelmyto (mitomycin) for pyelocalyceal solution
Description: The dose of Jelmyto to be instilled is 4 mg per mL via ureteral catheter or a nephrostomy tube, with total instillation volume based on volumetric measurements using pyelography, not to exceed 15 mL (60 mg of mitomycin).~Instill Jelmyto once weekly for six weeks. For patients with a complete response 3 months after Jelmyto initiation, Jelmyto instillations may be administered once a month for a maximum of 11 additional instillations.
Study: NCT05898971

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Physical Therapy
Description: Traditional exercise and Neurophysiological approaches
Study: NCT05305066

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TNFi
Description: TNFi - any sub-cutaneous (sc) formulation, namely etanercept (receptor fusion protein) 50 mg sc per week, adalimumab (monoclonal antibody) 40 mg sc every 2 weeks, golimumab (monoclonal antibody) 50 mg sc every month, or certolizumab (pegylated fragment of a monoclonal antibody) 400 mg sc at week 0, 2 and 4, and then 200 mg sc every 2 weeks or 400 mg sc every 4 weeks.
Study: NCT04726319

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FHAMe Intervention
Description: Patients will receive an invitation email prior to their scheduled clinical visit which includes information about the study, a link to the YouTube patient presentation, and a link to the consent form and questionnaire. Patients will be invited to fill out the questionnaire prior to their appointment. After patients complete the initial questionnaire, physicians will receive an EMR message on the day of patient's clinic visit alerting them that patient family history information is available and to complete the Family History Action Form. They will be prompted to respond to the message which will open the action form and ask what action the provider intends to take with this family history information. The form will then link to management support tools for use during the patient visit. All participants will attend their clinical visit after which they will receive a post-visit electronic survey regarding their clinical visit and whether family history was reviewed with their provider.
Study: NCT05305066

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anti-IL6
Description: Anti-IL6 receptor monoclonal antibodies - tocilizumab (if weight \<100 kg: 162 mg SC every other week, followed by an increase to weekly based on clinical response; if weight ≥100 kg: 162 mg SC weekly) or sarilumab (200 mg SC once every 2 weeks)
Study: NCT05925530

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Participants that go on to receive surgery, will receive durvalumab for up to four cycles prior to surgery. Participants that go on to receive CRT will receive durvalumab for up to two cycles prior to CRT. All participants will receive durvalumab every four weeks until disease progression or recurrence or up to 12 months following surgery/CRT, unless there is unacceptable toxicity, withdrawal of consent, or another discontinuation criterion is met.
Study: NCT05305066

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anti-IL6
Description: Anti-IL6 receptor monoclonal antibodies - tocilizumab (if weight \<100 kg: 162 mg SC every other week, followed by an increase to weekly based on clinical response; if weight ≥100 kg: 162 mg SC weekly) or sarilumab (200 mg SC once every 2 weeks)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: JAKi
Description: JAKi - tofacitinib (JAK1/3 inhibitor) 5 mg po bid, baricitinib 2 mg po qd (JAK 1/2 inhibitor) or upadacitinib 15 mg po qd (JAK1 inhibitor)
Study: NCT05677035

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LINO-1713 1 tablet
Description: LINO-1713 1 tablet is administered once. Oral administration with 200mL of water

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LINO-1713 once a day for 24 days
Description: Oral administration is performed with 200 mL of water. Instruct subjects to take the drug at the same time as possible.
Study: NCT05288439

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Resting-state functional connectivity MRI
Description: participants will undergo functional MRI

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Resting-state functional connectivity MRI
Description: participants will undergo functional MRI

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurocognitive battery with quality-of-life assessment
Description: Cognitive and quality of life assessments performed by a trained neuropsychologist

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurocognitive battery with quality-of-life assessment
Description: Cognitive and quality of life assessments performed by a trained neuropsychologist
Study: NCT06347523

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: The VR-based preoperative rehabilitation program;
Description: Patients are provided with VR headsets for personalized pre-rehabilitation educational videos prior to surgery. These videos cover psychological counseling, nutritional advice, and exercise instructions. Additionally, patients engage in VR interactive functional training. After surgery, patients continue with VR technology interactive functional training and watch postoperative educational videos. This intervention is initiated upon the patient's admission and continues until their discharge.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: standard nursing care,
Description: Patients in the control group receive traditional preoperative rehabilitation methods, which may include the following interventions: Joint exercises and rehabilitation exercises guided by a physical therapist. Written or verbal rehabilitation educational materials.
Study: NCT06040164

Intervention type: OTHER
Intervention: Observational study
Description: No intervention will be performed

Intervention type: OTHER
Intervention: Observational study
Description: No intervention will be performed

Intervention type: OTHER
Intervention: Observational study
Description: No intervention will be performed

Intervention type: OTHER
Intervention: Observational study
Description: No intervention will be performed
Study: NCT06583759

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Full coverage Crowns
Description: The crown will be prepared accordingly. Try in of the best fitted crown will be done and cementation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Full coverage Crowns
Description: The crown will be prepared accordingly. Try in of the best fitted crown will be done and cementation.
Study: NCT06108206

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adaptive Radiotherapy
Description: Each patient will undergo a brain MRI at the following time points:~1. Baseline- within 2 weeks prior to the start of chemo-RT,~2. Week #1- on Fractions # 4 or 5~3. Week #2- between Fractions # 6-10 (at least 5 days after the Week 1 MRI)~4. Week #3- between Fractions # 11-15 (at least 5 days after the Week 2 MRI)~5. Week #4- between Fractions # 16-20 gadolinium contrast (at least 5 days after the Week 3 MRI)~6. Week #5- on Fractions # 24 or 25 (after the start of the Conedown)~7. Week #6- +/- 3 days of Fraction #30 (end of RT)~Patients receiving hypofractionated radiotherapy will undergo a brain MRI at the following time points:~1. Baseline- within 2 weeks prior to the start of your standard of care chemotherapy radiation treatment (chemo-RT),~2. Week #1 - on Fractions #4 or 5~3. Week #2 - between Fractions #6-10 (at least 5 days after the Week 1 MRI)~4. Week #3 - between Fractions #11-15 (at least 5 days after the Week 2 MRI)
Study: NCT05119101

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamedotomidine added to Magnesium sulfate
Description: we will give dexamedotomidine and mg sulphate and then measure intracranial pressure at different intervals by measuring Optic nerve sheath diameter (ONSD).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium sulfate
Description: we will give mg sulphate and then measure intracranial pressure at different intervals by measuring Optic nerve sheath diameter (ONSD).
Study: NCT05721482

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiver Training
Description: A trained MIM provider and dietitian will deliver the MIM DASH group intervention in eight weekly 1-hour sessions via telehealth. Participants will receive session materials so they can follow along. Each MIM session consists of material related to mindfulness-the somatic mind/body connection, relaxation, yoga, meditation, self-awareness, and bodily cues relating to emotional reactivity. Group interaction centers on sharing ideas toward effective practice and practical daily challenges to being mindful. Each class begins with a prompt for participant contemplation during the next hour that reference a unique weekly theme which will be reiterated in the session materials.~The DASH portion, led by the Registered Dietitian, focuses on education to increase vegetables, fruits, whole grains and decrease intakes of fat and sodium, sugar sweetened beverages and sweets. Education includes adapting traditional Soul food dishes to meet the DASH dietary guidelines.
Study: NCT05137899

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Neoadjuvant
Description: Neoadjuvant atezolizumab/bevacizumab or neoadjuvant SBRT prior to hepatectomy

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Neoadjuvant
Description: Neoadjuvant atezolizumab/bevacizumab or neoadjuvant SBRT prior to hepatectomy
Study: NCT05508919

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Biofeedback
Description: EMG, RESP, and TEMP Biofeedback Training

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Writing Sessions
Description: The subjects will be asked to take three 20-minute writing sessions and write about the given control topic about their daily events of the past week
Study: NCT06068036

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telehealth intervention: HEARTS technical package + activity monitor (Smartwatch Mi Band 7®)
Description: Telehealth intervention involving the HEARTS technical package and the use of Smartwatch Mi Band 7® activity monitor. The HEARTS technical package presents the 5As brief intervention (Ask, Advise, Assess, Assist, Arrange) to promote physical activity participation. Participants will receive a physical activity monitor (as instructed in the HEARTS technical package) and will be monitored by telephone call, once a week, in order to reinforce successes and identify solutions to difficulties (as instructed in the HEARTS technical package) to practice physical activity. These individuals will undertake a 12-week intervention program. In the first week, individuals will perform the first four steps of the 5As brief intervention in person, where they will be instructed on how to use the physical activity monitor, they will receive a diary of regular physical activity practice, will be guided on how to fill it out, and will schedule the best times to receive the weekly telephone call.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Telehealth intervention: HEARTS technical package
Description: The same intervention as the experimental group, but without the additional use of the physical activity monitor (Smartwatch Mi Band 7®).
Study: NCT06066398

Intervention type: PROCEDURE
Group type: OTHER
Intervention: medical thoracoscope
Description: Medical thoracoscopy will be performed during which pleural brush will be used first followed by forceps biopsy to obtain pleural specimens from suspect areas under visual control and pleural lavage will be performed by injecting 300 mL of normal saline

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Forceps biopsy and pleural brush histopathology
Description: Forceps biopsy and pleural brush will be obtained for histopathological examination for diagnosis

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: pleural lavage cytology
Description: pleural lavage will be obtained for cytological examination for diagnosis
Study: NCT05710809

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement
Description: Vestibular rehabilitation, balance- and progressive resistance training for three months' three times/week and Comprehensive Geriatric Assessement including corresponding interventions
Study: NCT06125782

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Omega 3 fatty acid
Description: Omega 3 fatty acid 1 gm softgel capsule- 1 for children at or below 25 kg and two for above 25 kg.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of Omega-3 fatty acid softgel capsule
Description: Placebo of Omega-3 fatty acid softgel capsule- colour and shape almost similar to the original drug- 1 for children at or below 25 kg and 2 for above 25 kg.
Study: NCT05844241

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music and Theta Auditory Beat Stimulation
Description: Listening to music and ABS for 30 minutes.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Audiobooks
Description: Listening to audiobooks for 30 minutes
Study: NCT05615207

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imagery as compared to physical practice for balance tasks
Description: We will investigate if using motor imagery (mentally imagining and practicing a task) as a means of balance training is as effective as physical practice

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Motor Imagery as compared to physical practice for balance tasks
Description: We will investigate if using motor imagery (mentally imagining and practicing a task) as a means of balance training is as effective as physical practice
Study: NCT05615740

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Optical coherence tomography (OCTA)
Description: OCTA can detect the passage of individual blood elements (mostly erythrocytes) through capillaries and larger vessels in real-time

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Optical coherence tomography (OCTA)
Description: OCTA can detect the passage of individual blood elements (mostly erythrocytes) through capillaries and larger vessels in real-time
Study: NCT05281198

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: tart cherry juice
Description: 2, 8oz bottles of Montmorency tart cherry juice daily; 8oz taken in AM, 8oz taken in PM

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2, 8oz bottles of placebo juice daily; 8oz taken in AM, 8oz taken in PM
Study: NCT05076890

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 15 mg/g Full Spectrum Hemp Extract
Description: HPMC capsules containing full spectrum standardized hemp extract in liquid form.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 50 mg/g Full Spectrum Hemp Extract
Description: HPMC capsules containing full spectrum standardized hemp extract in liquid form.