TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05077072

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Counseling
Description: Participate in CHAT counseling intervention

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electroencephalography
Description: Undergo EEG

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neurofeedback
Description: Undergo NFB intervention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT04809662

Intervention type: DRUG
Intervention: Imiquimod
Description: Patients with a diagnosis of actinic keratosis or warts that would be prescribed imiquimod as standard of care will be asked to apply 2 packets (or 2 full pumps) of imiquimod once daily before bedtime for two weeks and then leave on overnight for \~8 hours.~(a) A biopsy will be performed at the baseline visit on the pre-treatment skin and the skin where the medication will not be applied. The skin where the medication will not be applied will act as the negative control. A biopsy will then again be performed on day 10 of imiquimod treatment on the treated skin only, where the study drug was applied.
Study: NCT04801537

Intervention type: OTHER
Intervention: normal body temperature and warm extremities
Description: environmental temperature is set according to the standard method to keep normal body temperature and warm extremities

Intervention type: OTHER
Intervention: normal body temperature and cold extremities
Description: environmental temperature is set according to the standard method to keep normal body temperature, but cold extremities
Study: NCT04957615

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given IV
Study: NCT06120530

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Intraperitoneal Bupivicaine without epinephrine 30 mg administered following completion of pelvic organ prolapse repair.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Placebo
Study: NCT06401434

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: On-site radiologist
Description: All participants in this arm will be screened by CXR. All CXR images will be interpreted by only an on-site radiologist. Participants with an abnormal CXR result from the radiologist will be indicated for follow-on diagnostic testing with the Xpert MTB/RIF Ultra assay.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CAD-based triage (with INSIGHT CXR software)
Description: All participants in this arm will be screened by CXR. All CXR images will first be processed with the INSIGHT CXR CAD software (Lunit, South Korea) to identify the totally normal/clear CXR images; only those with the possibility of containing an abnormality (abnormality score ≥ 20) will be sent to the on-site radiologist for reading/interpretation. Participants with an abnormal CXR result from the radiologist will be indicated for follow-on diagnostic testing with the Xpert MTB/RIF Ultra assay.
Study: NCT05895578

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: 1 capsule of probiotic (Lactobacillus CECT 9422 + Bifidobacterium CECT 30257) every 12 hours for 6-months.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic + placebo
Description: 1 capsule of probiotic + 1 capsule of placebo per day for 6-months.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 capsule of placebo every 12 hours for 6-months.
Study: NCT05536908

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Residential Written Exposure Therapy
Description: Residential Written Exposure Therapy (resWET): TAU plus 5-individual WET sessions (40-60 min each; Marx \& Sloan, 2019) twice a week for two weeks and once a week for the final session, administered by WET trained psychologists, social workers, or postdoctoral residents. Treatment instructions are read, patients write for 30 minutes, and the writing is briefly processed. No formal written homework is required.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual
Description: Treatment as Usual (DOM SUD): The DOM SUD (TAU) is a 24-bed intensive SUD residential program with a typical 28-day length of stay. The program focuses on evidence-based treatments for SUD such as Cognitive-Behavioral Therapy, Motivational Enhancement Therapy, Medication Assisted Treatment, and Contingency Management therapy. Patients diagnosed with PTSD are typically referred to outpatient PTSD treatment following DOM SUD and often attend Seeking Safety during the program. Most of the programming is group-based though Veterans also have weekly individual case management appointments.
Study: NCT06352203

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: 1 dose of the probiotic every 24 hours, for 6-months.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 dose of the placebo every 24 hours, for 6-months.
Study: NCT04815109

Intervention type: OTHER
Intervention: Encephalography measurement
Description: Encephalography measurement and partially aggravated sedation.
Study: NCT05426954

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation utilizing blood flow restrictive therapy
Description: BFR therapy
Study: NCT05077072

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05343572

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Plerixafor
Description: A 20mg single dose of PLERIXAFOR is administered subcutaneously the evening prior to scheduled standard of care surgery for women with AS, AE or RIF for peripheral mobilization of stem cells. For subjects weighing \>83 kilogram, the dosing is a single dose of 0.24 milligram per kilogram.
Study: NCT06352996

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three-Dimensional Assessment of Maxillary Canine Retraction with Power Arm
Description: A nickel titanium closed coil spring will be stretched from the mini-implant to the power arm will be used for canine retraction.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three-Dimensional Assessment of Maxillary Canine Retraction without Power Arm
Description: A nickel titanium closed coil spring will be stretched from the mini-implant to the canine bracket will be used for canine retraction.
Study: NCT04932525

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Blood and tumor samples for Genetic Profiling research
Study: NCT05903300

Intervention type: OTHER
Intervention: Surveys and Questionnaires
Description: The intervention consists of completing the MIPIM-P, QuickDash, and Brief Pain Inventory questionnaires.
Study: NCT06572397

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: H-1337 1.0%
Description: ophthalmic solution
Study: NCT06149442

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dose of five-incisions dry needling technique
Description: Once we have assessed the existence of a myofascial trigger point in the levator scapulae muscle, and while the subject is in lateral decubitus on the same side, with a forceps palpation, we apply a rapid in /out dry needling technique (five incisions).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dose of ten-incisions dry needling technique
Description: Once we have assessed the existence of a myofascial trigger point in the levator scapulae muscle, and while the subject is in lateral decubitus on the same side, with a forceps palpation, we apply a rapid in /out dry needling technique (ten incisions).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dose of fifteen-incisions dry needling technique
Description: Once we have assessed the existence of a myofascial trigger point in the levator scapulae muscle, and while the subject is in lateral decubitus on the same side, with a forceps palpation, we apply a rapid in /out dry needling technique (fifteen incisions).
Study: NCT05761041

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Fluoride Varnish (5%)
Description: Applied at baseline

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Two MI sessions: face-to-face at baseline and phone call at 3 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SDF
Description: Applied bianually
Study: NCT05012124

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Collaborative care
Description: Receive u-CoCM

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview or Focus Group
Description: Participate in an interview or focus group

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Media/technology Intervention with collaborative care
Description: Use t-CoCM digital platform with collaborative care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Complete surveys

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Complete surveys
Study: NCT05999734

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Before skin incision, under complete aseptic precautions and sterilization, the patient will be placed in a lateral position. The spinous process of the fourth thoracic vertebra will be identified and marked. The ultrasound guided MTP block will be done by high frequency linear transducer will be placed in position just lateral to the spinous processes of thoracic vertebra target of the paravertebral space. A 50 mm 22-gauge echogenic needle will be inserted in an in plane technique from a caudal to a cephalad direction and will be advanced. When the needle tip reaches the midpoint between the transverse process and the pleura, 1 ml normal saline will be injected. Once the needle tip has been confirmed and after careful aspiration to demonstrate the absence of air or blood, 0.5mL/kg 0.25% bupivacaine will be injected.
Study: NCT05155293

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AVT06 (proposed aflibercept biosimilar)
Description: Patients will receive IVT injections of AVT06

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eylea® (Aflibercept)
Description: Patients will receive IVT injections of Eylea®
Study: NCT05756465

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartphone-based virtual reality relaxation (SVR)
Description: SVR is virtual relaxation and distraction therapy through a smartphone-based VR device (head-mounted display) that is attached to the head of a cancer patient undergoing chemotherapy, displaying a virtual environment of natural panoramas in 360-degree video and combined with traditional and classic musical instruments. SVR device is paired with smartphone using operating system either Android (minimum generation 11, Android 4.4 KitKat) or OS version 12, minimum screen size of 5.5-inch and maximum of 6.0-inch, screen resolution of at least 1080 x 1920 pixels, can connect to WIFI/ internet and provides a YouTube app to access 360-degree videos. SVR content uses original 360o videos produced by researchers using a video editor software for ± 10 minutes duration.
Study: NCT06561321

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tapinarof
Description: Daily topical Tapinarof use will stop disease advancement and improve the quality of life in patients with palmoplantar keratoderma, through its AhR \& NRF2 agonism properties.
Study: NCT06641557

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 200mg of Ikt-148009
Description: 4 50mg capsules
Study: NCT06639516

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bifidobacterium longum
Description: Bifidobacterium longum

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Standard clinical treatment
Description: Fasting, gastrointestinal decompression, rehydration, inhibition of pancreatic fluid and pancreatic enzyme secretion, improvement of microcirculation, and support of organ function if organ dysfunction occurs at a later stage (mechanical ventilation, continuous renal replacement therapy, and the use of vasoactive drugs).

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Standard clinical treatment
Description: Fasting, gastrointestinal decompression, rehydration, inhibition of pancreatic fluid and pancreatic enzyme secretion, improvement of microcirculation, and support of organ function if organ dysfunction occurs at a later stage (mechanical ventilation, continuous renal replacement therapy, and the use of vasoactive drugs).
Study: NCT06636916

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Short Intervals HIIT
Description: Participants will undergo different high-intensity interval training (HIIT) protocols, which involve repeated bouts of exercise at an intensity above 90% of VO2max, followed by recovery periods. The work and rest durations will vary across the protocols to assess the impact on the total time spent at or above 90% of VO2max.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Short Intervals HIIT
Description: Participants will undergo different high-intensity interval training (HIIT) protocols, which involve repeated bouts of exercise at an intensity above 90% of VO2max, followed by recovery periods. The work and rest durations will vary across the protocols to assess the impact on the total time spent at or above 90% of VO2max.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Long intervals HIIT
Description: Participants will undergo different high-intensity interval training (HIIT) protocols, which involve repeated bouts of exercise at an intensity above 90% of VO2max, followed by recovery periods. The work and rest durations will vary across the protocols to assess the impact on the total time spent at or above 90% of VO2max.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Long intervals HIIT
Description: Participants will undergo different high-intensity interval training (HIIT) protocols, which involve repeated bouts of exercise at an intensity above 90% of VO2max, followed by recovery periods. The work and rest durations will vary across the protocols to assess the impact on the total time spent at or above 90% of VO2max.
Study: NCT06643104

Intervention type: PROCEDURE
Intervention: Tuina
Description: X-ray mapping guides three days of tailored exercises, including 3D therapy, breathing techniques, and spinal manipulation.
Study: NCT06027905

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E3 Remote Monitoring and Social Intervention
Description: Patients are enrolled in a 12 week remote blood pressure monitoring program composed of a community health worker, nurse, pharmacist and social worker. Participants will receive a home cellular blood pressure cuff for remote monitoring and will receive tele-health calls from their community health worker to assist with blood pressure taking technique and adherence, medication adherence, education around diet and activity. Social work is available to provide institutional and community resources to patients with social needs. Patients will be screened pre intervention and post intervention for medication adherence and social determinants of health needs. The team nurse monitors and triages home blood pressures on the remote portal. The pharmacist assists with medication reconciliation, adherence, and titration of medications according to standards or care.
Study: NCT05671705

Intervention type: DIAGNOSTIC_TEST
Intervention: DEXA Scan
Description: Fu of diagnostic tests
Study: NCT05179915

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Touch focused on sacral region
Description: In the latent phase of labor, the field energy of the sacral region will be cleared for an average of 15 minutes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Therapeutic Touch focused on sacral region
Description: In the latent phase of labor, the field energy of the sacral region will be cleared for an average of 15 minutes.
Study: NCT05142293

Intervention type: OTHER
Intervention: Ambulatory procedure
Description: In the same-day hospitalization group, some patients will be hospitalized on an ambulatory process
Study: NCT00728533

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Degarelix
Description: Prostate Cancer - Degarelix powder and solvent for suspension for injection. Three-month depot in two dosing regimens.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Degarelix
Description: Prostate Cancer - Degarelix powder and solvent for suspension for injection. Three-month depot in two dosing regimens.
Study: NCT06265818

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation training
Description: Including 1) Basic treatment, including corresponding control of risk factors and education on healthy lifestyles. 2)Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation training
Description: Including 1) Basic treatment, including corresponding control of risk factors and education on healthy lifestyles. 2)Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Breathing Exercises
Description: Active breathing exercises aim to enhance the strength and flexibility of respiratory muscles through a series of exercises, improving breathing patterns and increasing respiratory efficiency. The following are common components of active breathing exercises: 1) Deep Breathing. 2) Chest Expansion. 3) Diaphragmatic Breathing. 4) Coughing Techniques. 5) Expiratory Resistance Training. 6) Gradual Increase in Activity.
Study: NCT05806190

Intervention type: DEVICE
Intervention: Continuous Glucose Monitoring
Description: Continuous Glucose Monitoring using a Dexcom G6 Continuous Glucose Monitoring Device

Intervention type: DEVICE
Intervention: Continuous Glucose Monitoring
Description: Continuous Glucose Monitoring using a Dexcom G6 Continuous Glucose Monitoring Device
Study: NCT06569485

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trilaciclib+R-CHOP
Description: This is a prospective, single-arm, multi-center, phase II clinical study to evaluate the efficacy and safety of Trilaciclib in DLBCL patients treated with R-CHOP.
Study: NCT06569407

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online Educational Intervention
Description: An educational program for EBP based on the online learning model was planned to be developed based on the literature and expert opinions. In the program, in line with the literature, the introduction to the EBP, the importance of EBP, EBP steps, clinical research question design in line with PICO, and introduction of EBP databases. It is planned to include topics such as literature search strategies, types of research, use of scientific research and evidence evaluation tools, introduction of clinical decision support systems, reflection of EBP on patient care and clinical decision-making processes, and it is planned to determine the final version of the education content with expert opinions. The program will include recorded videos, slides and documents for each module. The content of the program will be integrated into the Koç University Online Programs Platform by the experts working at Koç University Educational Technologies Unit.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Educational Booklet
Description: An educational booklet for EBP was planned to be developed based on the literature and expert opinions. The learning objectives and content of the educational booklet to be developed will be created by considering Bloom\&#39;s taxonomy. In line with the literature, it is planned to include topics such as introduction to EBP, importance of EBP, evidence-based practice steps, clinical research question design in line with PICO, introduction of evidence-based databases, literature search strategies, research types, use of scientific research and evidence evaluation tools, introduction of clinical decision support systems, reflections of EBP on patient care and clinical decision-making processes, and finalization of the booklet topics with expert opinions.
Study: NCT05405608

Intervention type: DRUG
Intervention: Ondansetron
Description: hemodynamic stability in orthopedic surgeries

Intervention type: DRUG
Intervention: Ondansetron
Description: hemodynamic stability in orthopedic surgeries
Study: NCT05914129

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diaphragm, Stomach and Liver techniques
Description: Diaphragm Stretching:~The participant is seating down and the researcher will be behind, placing their hands on the inferior costal border. Cephalic traction is performed during inhalation, remaining during exhalation. Procedure is repeated 2 times, for 10 respiratory cycles, with 1-minute intervals.~Inferior Mobilization of the Stomach:~The participant is seating down with slight flexion of the torso, while the investigator stands behind them, placing the thumbs on the epigastric region. The volunteer will extend their body while the researcher performs a caudal traction. This procedure lasts 5 minutes.~Liver Pump:~Participant is laying on their back, and the investigator is standing on the participants side. The researcher places one hand on the right side inferior costal border posteriorly and the other one bellow the costal border anteriorly. Researcher compresses during exhalation and releases their hands abruptly during inhalation. This procedure lasts 5 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stomach and Liver techniques
Description: In this group, techniques are the exact same as described previously but only liver and stomach ones will be performed.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham technique
Description: In the sham group, manual contact without any therapeutic intention will be performed in the same regions as the experimental groups. This contact will be maintained during the same amount of time as for the experimental group A.
Study: NCT06284018

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive Muscle Relaxation Exercises
Description: * Focus on the targeted muscle group.~* Take a slow, deep breath while squeezing on muscle group as hard as she can (not to the point of strain). Keep the muscle tensed for 5 seconds.~Hands and arms, forehead ,Eyes and Cheek, Mouth and Jaw , Neck and Shoulder ,Stomach , Leg and Toes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates Exercises
Description: Pilates exercise program consisted of floor exercises on a rubber mat, including the following exercises: a- Pelvic Curl. b- Single-Leg Lift. c- Chest Lift. d- Supine Spine Twist. e- Basic Back Extension.