TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06563934

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Oral enterobacterium capsules
Description: Enterobacterium capsules (300 mg/per capsule) orally 6 capsules/day for 10 consecutive days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib + PD-1 monoclonal antibody
Description: Lenvatinib 8mg (≤60 kg body weight) or 12 mg (\> 60 kg body weight) orally once a day.~PD-1 monoclonal antibody 200mg i.v. once every 3 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lenvatinib + PD-1 monoclonal antibody
Description: Lenvatinib 8mg (≤60 kg body weight) or 12 mg (\> 60 kg body weight) orally once a day.~PD-1 monoclonal antibody 200mg i.v. once every 3 weeks.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Oral enterobacterium capsules placebo
Description: Enterobacterium capsules placebo (300 mg/per capsule) orally 6 capsules/day for 10 consecutive days.
Study: NCT05500534

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Laser lithotripsy with stone recognition
Description: Application of Revolix HTL+ which features automatic real-time stone recognition

Intervention type: OTHER
Group type: OTHER
Intervention: Laser lithortripsy
Description: Standard laser lithotripsy
Study: NCT04993196

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: T1rho imaging
Description: Magnetic Resonance Imaging using T1rho
Study: NCT06642064

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention group
Description: • Intervention group:~Participants were invited to participate in a 20-minute interactive learning course (PPT lecture) and a 25-minute physical activity.The intervention lasted for 12 weeks, twice a week, 45 minutes each time, for a total of 1080 minutes.
Study: NCT06434493

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Proton Beam Therapy
Description: All patients to be offered neoadjuvant proton beam therapy to a dose of 45 Gray (Gy) in 15 fractions over 3 weeks, with a tumour boost to 67.5 Gray (Gy)
Study: NCT06291090

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OUD treatment intervention
Description: Participants received education on the diagnosis and management of OUD, have access to protocols to walk them through assessment of OUD using Diagnostic and Statistical Manual, fifth Edition (DSM)-5, COWS score to calculate severity of opioid withdrawal, buprenorphine or methadone initiation with pre-populated orders, and clickable links for OUD treatment referral post discharge.
Study: NCT05979259

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Serious game nutrition education intervention
Description: Classrooms will receive nutrition education lessons for 35-40 minutes for 5 consecutive days. As part of each lesson, students will play the Foodbot Factory nutrition education serious game for 10-15 minutes. The Foodbot Factory serious game and lessons are based on Ontario curriculum requirements and aligned Canada's Food Guide.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional nutrition education intervention
Description: Classrooms will receive nutrition education lessons for 35-40 minutes for 5 consecutive days. As part of each lesson, students will use conventional learning activities, such as worksheets, sourced from an online teaching resource repository. The lessons are based on Ontario curriculum requirements and aligned Canada's Food Guide.
Study: NCT06434493

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Concurrent oral capecitabine chemotherapy
Description: All patients to be offered concurrent oral capecitabine 625mg/m2 twice daily on radiation days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin & Gemcitabine intravenous chemotherapy
Description: Following chemoradiotherapy (PBT + capecitabine), and whilst on the liver transplant waiting list, patients will be offered up to 6 cycles of standard chemotherapy with cisplatin and gemcitabine.
Study: NCT05327426

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Intradermal fractional dose inactivated polio vaccine (fIPV) in combination with recombinant double mutant heat labile toxin, LT(R192G/L211A), (dmLT)
Description: Sanofi's licensed IPOL trivalent inactivated polio vaccine (NDC 49281-860-78) delivered at the dose-sparing fractional volume of 1/5 the full dose (0.1mL) admixed with 0.47µg of recombinant double mutant \[LT(R192G/L211A)\] Enterotoxigenic Escherichia coli heat labile toxin (dmLT) adjuvant.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Intradermal fractional dose inactivated polio vaccine (fIPV)
Description: Sanofi's licensed IPOL trivalent inactivated polio vaccine (NDC 49281-860-78) delivered at the dose-sparing fractional volume of 1/5 the full dose (0.1mL).

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Monovalent oral poliomyelitis vaccine (mOPV), Sabin strain
Description: Monovalent oral polio vaccine (OPV) challenge administered as a test of mucosal immunity.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Monovalent oral poliomyelitis vaccine (mOPV), Sabin strain
Description: Monovalent oral polio vaccine (OPV) challenge administered as a test of mucosal immunity.
Study: NCT05822141

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fish Oil
Description: For 12 weeks subjects will ingest 6 capsules per day of fish oil (7.8 g/day total omega--3 fatty acids: 3.75 g/day EPA and 1.5 g/day DHA)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: For 12 weeks subjects will ingest 6 capsules per day of olive oil (each capsule contains 990 mg of olive oil)
Study: NCT04555044

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clinolipid
Description: Lipid injectable emulsion, USP 20%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intralipid
Description: Standard-of-Care Soybean Oil-Based Lipid Emulsion. 20% (lipid injectable emulsion, USP)
Study: NCT05381701

Intervention type: PROCEDURE
Intervention: Lung Ultrasound Score
Description: Measuring the atelectasis area by ultrasound guidance from 12 different regions of the lung

Intervention type: PROCEDURE
Intervention: Lung Ultrasound Score
Description: Measuring the atelectasis area by ultrasound guidance from 12 different regions of the lung

Intervention type: PROCEDURE
Intervention: Lung Ultrasound Score
Description: Measuring the atelectasis area by ultrasound guidance from 12 different regions of the lung
Study: NCT05701592

Intervention type: PROCEDURE
Intervention: DB-PCLR
Description: DB-PCLR with reconstruction of both PCL bundles: anterolateral and posteromedial bundle will be performed.
Study: NCT04272073

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-Protein Mediterranean Diet
Description: As in arm/group descriptions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Exercise
Description: As in arm/group descriptions

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Dietary Advice
Description: As in arm/group descriptions

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Cardiac Rehabilitation Exercise
Description: As in arm/group descriptions
Study: NCT06113939

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: airway clearance
Description: mechanical suctioning of airway secretions

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: airway clearance
Description: mechanical suctioning of airway secretions

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: airway clearance
Description: mechanical suctioning of airway secretions
Study: NCT05014204

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Endogenex Device
Description: The Endogenex device is designed to induce duodenal mucosal regeneration using pulsed electric field. The Endogenex procedure is a non-surgical, endoscopic procedure.
Study: NCT05610696

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low impact immersion
Description: Consists of a sequence of shoulder, trunk and hip movements. In this modality, the aim will be to understand the physiological effects of immersion in heat water. Resisted movements (either by turbulence or by floats) or interventional maneuvers in the knee joints will not be performed. Considering the period of 5 minutes for acclimatization to the liquid environment, the program will last approximately 47 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional aquatic physiotherapy
Description: include warm-up, strengthening and calming down activities. Aquatic steppes will be used to ensure that all participants will maintain the waterline level approximately in the xiphoid appendix. For strengthening activities, the exercises must be performed at an adequate speed, which ensures a comfortable level for the activity. For this purpose, a subjective feedback will be extracted from the participants constantly. The warm-up sequence consists of six different active hip and knee movements performed at maximum range of motion and contributes to neuromuscular activation. For strengthening, each movement should be performed for 1 minute (30 seconds for each lower limb) followed by a period of 30 seconds of rest between each movement.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High intensity aquatic physiotherapy
Description: In this modality subjects will perform the same sequence of exercises of the Conventional Aquatic Physiotherapy program will be respected. However the work load and speed will be adjusted to the maximum level. For strengthening, each movement should be performed for 2 minutes (1 minute for each lower limb) followed by a period of 30 seconds of rest between each movement. To guarantee the maximum effort of the participants, verbal stimuli will be constantly provided. The program will last approximately 68 minutes.
Study: NCT06059820

Intervention type: OTHER
Intervention: rehabilitation treatment
Description: 3-month immobilization period, hyperextension braces for specific fractures, therapeutic exercises, and gradual activity restoration.

Intervention type: PROCEDURE
Intervention: Spine fusion
Description: Pedicle screw fixation or fusion; anterior plate fusion
Study: NCT04731610

Intervention type: OTHER
Group type: OTHER
Intervention: Radiotherapy
Description: postoperative radiotherapy after complete resection of thymoma

Intervention type: OTHER
Group type: OTHER
Intervention: Surveillance after resection
Description: Surveillance after tumour resection
Study: NCT05541263

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Stress Reduction
Description: The intervention used is an MBSR training which is based on the Mindfulness-Based Stress Reduction programme as developed by Kabat-Zinn (1982). The training consists of 8 weekly sessions lasting 2,5 hours. A silent day of approximately 6 hours is also included, as well as daily home practice assignments of about 45 minutes. During the training participants will learn to focus their attention in the present moment in an accepting and non-judgemental way, rather than ruminating about past and future experiences. The training includes formal exercises during which participants will practice the body scan, sitting meditation, walking meditation and mindful movement. Informal exercises are also included, such as performing a daily activity with full attention to the present experience. The training is led by qualified teachers meeting the advanced criteria of the Association of Mindfulness Based Teachers in the Netherlands and Flanders (www.vmbn.nl)
Study: NCT05073601

Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA,DNA extraction
Description: quantitative measurement of (Thyroid stimulating hormon (TSH), free triiodothyronine (FT3)\& Free tetraiodothyronine(FT4)) measured using ELISA . Serum 25-OH vitamin D measured using ELISA. Serum 25-OH vitamin D will be classified based on 2012 American Endocrine Society guidelines into deficient (\< 20ng/ml), insufficient ( 21 -30 ng/ml) and sufficient (\> 30 ng/ml).vitamin D receptor polymorphisms was done in 3 steps: a) DNA extraction from whole blood using Gene Jet gene DNA Purification kits . b) PCR: three Vitamin D receptor polymorphisms were tested \[Taq I (restriction enzymes according to single nucleotide polymorphism ) (rs731236), Apa I (rs7975232) and Bsm I (rs1544410)\] using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Genomic DNA was amplified using certain primers
Study: NCT05717686

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AHB-137 injection
Description: AHB-137 will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AHB-137 injection
Description: AHB-137 will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AHB-137 injection
Description: AHB-137 will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AHB-137 injection
Description: AHB-137 will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered
Study: NCT05187767

Intervention type: DIAGNOSTIC_TEST
Intervention: cf DNA and ct DNA
Description: Quantification of the circulating free DNA and the presence of targeted circulating tumor DNA

Intervention type: DIAGNOSTIC_TEST
Intervention: cf DNA and ct DNA
Description: Quantification of the circulating free DNA and the presence of targeted circulating tumor DNA
Study: NCT06308367

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Betaine
Description: 50mg/kg for 12 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT04921423

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Situational simulation teaching
Description: The intervention included communication theory and skills, aging trend and knowledge, teaching plans for elderly nursing, activities for the elderly and visual experience, application and debriefing of empathy.
Study: NCT05200650

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: TumoCure
Description: TumoCure is a polymer-based gel, loaded with Cisplatin in a dose of 100mg (10% w/w), injected to head and neck tumors locally in a single injection.
Study: NCT04792853

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tab-G
Description: Participants receive a tablet preloaded with Tab-G application and an accelerometer.
Study: NCT05706493

Intervention type: OTHER
Group type: OTHER
Intervention: Non surgical periodontal treatment
Description: Non-surgical periodontal treatment will be performed using ultrasonic scaler and subgingival curettes
Study: NCT06164249

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strength training
Description: Strength training, three times a week, during nine weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strength training
Description: Strength training, three times a week, during nine weeks.
Study: NCT06505824

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BL-M14D1
Description: Administration by intravenous infusion for a cycle of 3 weeks.
Study: NCT04768920

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MI-CBT Teletx
Description: Participants will first receive a 20-45 min phone or video session focused on raising participants' motivation to engage in treatment activities and psychoeducation material about substance use (i.e. engagement session) including possible discussion about risks of substance use, value of alternative healthier activities, and the community and crisis resources pamphlet. The evidence-based manualized psychosocial programs that will be delivered via telehealth are adaptations of cognitive behavioral therapy, motivational interviewing, and other psychosocial interventions to enhance initial and ongoing treatment engagement. TeleTx consists of up to 8 \~30-50 minute psychosocial sessions delivered via phone or videoconference platform (e.g. Zoom etc)
Study: NCT04963621

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Child-Adolescent Emotion and Stress Intervention Program
Description: Intervention programs include Emotion and Stress Intervention for children with emotional and stress problems

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Child-Adolescent Emotion and Stress Intervention Program
Description: Intervention programs include Emotion and Stress Intervention for children with emotional and stress problems
Study: NCT05893303

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1st Group
Description: 1st group is going to undergo scapula-oriented PNF techniques (diagonal) which are anterior elevation and posterior depression - posterior elevation and anterior depression with 20 repetitions with rhythmic initiation and repeated contractions facilitation techniques during all patterns. In addition to PNF techniques, gait training is going to be applied as standing with balance exercises (15 repetitions) as well as specific exercises for the stance and swing phases of the gait which are; stepping forward and sideways (15 repetitions), and gait education (walking 3 lapses within 2 meters parallel bar)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 2nd Group
Description: 2nd group is going to undergo only gait training and balance exercises (15 repetitions) as well as specific exercises for the stance and swing phases of the gait which are; stepping forward and sideways (15 repetitions), and gait education (walking 3 lapses within 2 meters parallel bar)
Study: NCT06200636

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of the PELSA System for dISF extraction
Description: Dermal interstitial fluid will be extracted using the investigational device, for further analysis.
Study: NCT05902507

Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic Resonance Imaging Simulation
Description: Radiographic Image Simulation
Study: NCT05815368

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: REMO
Description: REMO training will consist of sEMG-biofeedback exercises provided by REMO device. The training will be provided 1 hour a day, for 5 days/week, for totally 3 weeks.
Study: NCT06434493

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Orthotropic Liver Transplant
Description: If still eligible after neoadjuvant treatment (PBT + capecitabine), patients will be added to the liver transplant waiting list.
Study: NCT05264454

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: high flow nasal cannulae
Description: The plan is to examine the effects of the size of the IVC size based upon varrying levels of high flow nasal cannulae flow

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: high flow nasal cannulae
Description: The plan is to examine the effects of the size of the IVC size based upon varrying levels of high flow nasal cannulae flow

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: high flow nasal cannulae
Description: The plan is to examine the effects of the size of the IVC size based upon varrying levels of high flow nasal cannulae flow
Study: NCT04609046

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration and Biopsy
Description: Undergo bone marrow aspirate and biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT and PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo ECHO
Study: NCT05485779

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AQ280
Description: Dose form: capsule, hard~Strength: 3 to 100 mg~Method of administration: oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AQ280
Description: Dose form: capsule, hard~Strength: 3 to 100 mg~Method of administration: oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AQ280
Description: Dose form: capsule, hard~Strength: 3 to 100 mg~Method of administration: oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AQ280
Description: Dose form: capsule, hard~Strength: 3 to 100 mg~Method of administration: oral
Study: NCT04609046

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Given PO
Study: NCT05686889

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient self-report
Description: Simulated patient following structured script

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient self-report
Description: Simulated patient following structured script
Study: NCT05714059

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Insulin Pump with Continuous Glucose Monitoring
Description: MiniMed™ 780G insulin pump in combination with the DS5 CGM
Study: NCT04609046

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lumbar Puncture
Description: Undergo lumbar puncture
Study: NCT05485779

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AQ280
Description: Dose form: capsule, hard~Strength: 3 to 100 mg~Method of administration: oral
Study: NCT04609046

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Given IV or PO

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound Imaging
Description: Undergo testicular ultrasound
Study: NCT05694494

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: internet-based Lifestyle-integrated Functional Exercise (iLiFE)
Description: receiving internet-based LiFE training and home safety assessment

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: upper limb exercise training
Description: upper limb exercise training
Study: NCT06565325

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise + Audible Cues
Description: Combined Terminal Knee Extension Exercise with Audible Cues
Study: NCT05815368

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Task-Oriented Training
Description: Task-Oriented training will consist of task-specific functional exercises. The training will be provided 1 hour a day, for 5 days/week, for totally 3 weeks.
Study: NCT05902468

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ursodeoxycholic acid
Description: ursodeoxycholic acid 500 mg orally twice daily for 12 weeks
Study: NCT06565325

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Terminal Knee Extension Exercise