TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05193279

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19
Study: NCT05376007

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Serious game 'Broodles'
Description: The serious game 'Broodles' is a newly developed web-based, educational game that can be played by siblings on a computer or tablet without support from an adult. The game discusses the nine domains of sibling quality of life (Moyson \& Roeyers, 2012) in eight 20-minute levels. The main characters of the game are the Broodles, which are little monster creatures that experience things that siblings of children with ID and/or VI can also experience. The game includes animations, videos of siblings talking about their experiences, quizzes and mini-games. These elements are focussed on emotions, thoughts and difficult situations that siblings can experience. In addition to the game, siblings make offline worksheets and parents receive an information brochure. Siblings complete the game in four weeks.
Study: NCT05627778

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-PSMA-11
Description: Intravenous injection of one dosage of 148-185 MBq (4-5 mCi) 68Ga-PSMA-11. Tracer doses of 68Ga- PSMA-11 will be used to image lesions of prostate cancer by PET/CT.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-P15-041
Description: Intravenous injection of one dosage of 148-185 MBq (4-5 mCi) 68Ga-P15-041. Tracer doses of 68Ga- 15-041 will be used to image lesions of prostate cancer by PET/CT.
Study: NCT05183828

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of saliva samples

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Description: Given PO
Study: NCT06024525

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Paclitaxel-Coated Coronary Balloon Catheters
Description: to Verify Effectiveness and Safety of Paclitaxel-Coated Coronary Balloon Catheters in SVD patients

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel-Releasing Coronary Balloon Catheters
Description: to Verify Effectiveness and Safety of Paclitaxel-Coated Coronary Balloon Catheters in SVD patients
Study: NCT04742673

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Guanfacine
Description: Patients randomized to the IV Guanfacine arm will receive intravenous guanfacine when they exhibit ICU delirium.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients randomized to the placebo arm will receive intravenous normal saline when they exhibit ICU delirium.
Study: NCT05821361

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HAIC+Cadonilimab+Bevacizumab
Description: Cadonilimab: 10mg/kg, iv,q3w Bevacizumab: 7.5mg/kg, iv, q3w HAIC: Oxaliplatin plus Fluorouracil/Leucovorin
Study: NCT05916586

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone 40 mg orally once a day for 7 days
Study: NCT06546982

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Surface-enhanced Raman Spectroscopy
Description: The Raman spectra of patient samples will be measured in the presence of gold nanoparticles, which will enhance the spectroscopic characteristics of serum components via near-field enhancements.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Surface-enhanced Raman Spectroscopy
Description: The Raman spectra of patient samples will be measured in the presence of gold nanoparticles, which will enhance the spectroscopic characteristics of serum components via near-field enhancements.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Surface-enhanced Raman Spectroscopy
Description: The Raman spectra of patient samples will be measured in the presence of gold nanoparticles, which will enhance the spectroscopic characteristics of serum components via near-field enhancements.
Study: NCT06415370

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Delivered Healthy Meals Plus Social Interactions
Description: In-person delivery of HDHM with friendly visits and also Student Companion calls at least one time weekly.~Friendly visits last approximately 5-10 minutes and include brief wellness check questions such as, How are you doing today? Did you try \[HDHM recipe\] yesterday- how did it taste? Any suggestions for future flavors? What are some of the things you plan to do in the next few days? Is there anything else you want to share with me?~Student Companions call participants at least one time weekly to provide telephone reassurance- i.e., checking on the participant's well-being. These calls may also include referrals to appropriate resources such as NCCARE 360 (statewide network that connects individuals with complex health and social needs, to community resources and service)~Facilitators of the Friendly Visits and Student Companion calls will use an online system to facilitate the sharing of information that would benefit the participants.
Study: NCT06499818

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: STABLE-SR
Description: homogenization of the low voltage zones and elimination of the complex electrograms from the transitional zones during sinus rhythm

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: STABLE-AF
Description: homogenization of the low voltage zones and elimination of the complex electrograms from the transitional zones during Atrial Fibrillation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CPVI
Description: ablate around the pulmonary vein orifice
Study: NCT05183828

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05070676

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: newly developed mobile application
Description: The application will be developed in native Android, using Java (backend) and XML (front-end) as the programming language. The program of choice will be Android Studio®, YouTube® (video reproduction) and Firebase® (database) will be used as external APIs (Application Programming Interfaces).~The layout of the application will be developed using:~Adobe Illustrator® software. The logo, brand, objects, and shapes of the mobile application will be designed to enable to resize of the images without any loss of quality, due to the wide range of scales available in current smartphones
Study: NCT06645483

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ChatGPT-assisted instruction
Description: ChatGPT will interactively support students by answering questions, initiating discussions, and providing customized learning materials in line with the course objectives. It will be supervised by the instructor to ensure guidance and prevent misinformation.~Duration: ChatGPT-assisted learning for the first two weeks, followed by traditional teaching for the next two weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional lecture-based instruction
Description: Students will learn through a traditional teaching format, where the instructor delivers the course content through lectures and presentations.~Duration: Traditional teaching for the first two weeks, followed by ChatGPT-assisted learning for the next two weeks.
Study: NCT05477030

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medtronic MiniMed 780G with SmartGuard activation
Description: Insulin pump implemented with alghoritm for automatic modulation of insulin delivery (to increase time in glucose range 70-180 mg/dl)

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medtronic MiniMed 780G without SmartGuard activation
Description: Insulin pump implemented with alghoritm for low glucose insulin suspension (to reduce hypoglycemia rate)
Study: NCT05953441

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AI-powered doctor
Description: AI-powered virtual doctor

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Human-controlled doctor avatar
Description: Virtual doctor avatar controlled by the medical student.
Study: NCT06291792

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telerehabilitation otago exercise program
Description: telerehabilitation otago exercise program

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: face to face otago exercise program
Description: face to face otago exercise program
Study: NCT04724148

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fentanyl
Description: To assess the accuracy of HVPG in TIPS after injecting a dose of 1\~2 mg/kg fentanyl.
Study: NCT06195202

Intervention type: DRUG
Intervention: AIs
Description: Patients with AIs

Intervention type: DRUG
Intervention: OFS+AIs
Description: Patients with OFS+AIs

Intervention type: DRUG
Intervention: FUL
Description: Patients with FUL
Study: NCT05680233

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OA-235i (4 mg)
Description: 3 participants will receive 4 mg as a single subcutaneous dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OA-235i (8 mg)
Description: 3 participants will receive 8 mg as a single subcutaneous dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OA-235i Dose 3
Description: 3 participants will receive a single escalating subcutaneous dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OA-235i Escalating Dose 4
Description: 3 participants will receive a single escalating subcutaneous dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OA-235i Escalating Dose 5
Description: 3 participants will receive a single escalating subcutaneous dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OA-235i Multiple Dose
Description: 8 participants will receive a daily subcutaneous dose for 7 consecutive days
Study: NCT06158503

Intervention type: DEVICE
Intervention: AID
Description: Initiation of an automated insulin delivery system
Study: NCT05160350

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Probiotic
Description: Each probiotic capsule contained combination of lactobacillus and Bifidobacterium species.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: Each probiotic capsule contained combination of lactobacillus and Bifidobacterium species.
Study: NCT05261282

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindful Hand Hygiene
Description: Physicians and nurses randomized to the intervention arm will receive mindfulness education and tools to prompt mindfulness during hand hygiene.
Study: NCT06199492

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tVisio-1
Description: Standard of Care Biopsy
Study: NCT06377241

Intervention type: DEVICE
Intervention: ScentAware
Description: ScentAware is a smell test

Intervention type: DEVICE
Intervention: ScentAware
Description: ScentAware is a smell test

Intervention type: DEVICE
Intervention: ScentAware
Description: ScentAware is a smell test

Intervention type: DEVICE
Intervention: UPSIT
Description: UPSIT is a smell test

Intervention type: DEVICE
Intervention: UPSIT
Description: UPSIT is a smell test

Intervention type: DEVICE
Intervention: UPSIT
Description: UPSIT is a smell test
Study: NCT06568172

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo collection of blood and/or plasma

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood and/or plasma

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: Given IV

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT and/or PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT and/or PET/CT

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Image Guided Radiation Therapy
Description: Undergo IGRT

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Image Guided Radiation Therapy
Description: Undergo IGRT

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Intensity-Modulated Radiation Therapy
Description: Undergo IMRT

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity-Modulated Radiation Therapy
Description: Undergo IMRT

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical Procedure
Description: Undergo surgery per SOC

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Procedure
Description: Undergo response-adaptive surgery
Study: NCT06345157

Intervention type: DRUG
Intervention: Ofatumumab
Description: This is an observational study. There is no treatment allocation. The decision to initiate treatment with ofatumumab (Kesimpta®) will be based solely on clinical judgement and according to the SmPC and AIFA reimbursement criteria.
Study: NCT06352606

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Spinal anesthesia
Description: Oxygen supply will be done via nasal prong (2 L/min) when necessary. The local anesthetic used will be bupivacaine 0.6 mg/kg.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: General anesthesia
Description: Patients will receive sevoflurane for induction and maintenance in an air/oxygen mixture along. Endotracheal tube will be inserted. No opioids or nitrous oxide was used intraoperatively.
Study: NCT04206644

Intervention type: OTHER
Intervention: biological analysis
Description: biological analysis of the Concentration of CCL18

Intervention type: OTHER
Intervention: biological analysis
Description: biological analysis of the Concentration of CCL18
Study: NCT06061146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arm A
Description: anti-PD-1 immunotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arm A
Description: chemotherapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Arm A
Description: Radiation Concurrent Radiation, 1.8Gy/f, 28f

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Arm B
Description: chemotherapy

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Arm B
Description: Radiation Concurrent Radiation, 1.8Gy/f, 28f
Study: NCT05958563

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: continuous positive airway pressure treatment
Description: CPAP treatment for one year
Study: NCT06064136

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Psoas tenotomy under ultrasound
Description: Tenotomy of the ilio-psoas tendon under ultrasound is performed using an ultrasound machine, a 3 mm Acufex hook blade and a specific kit usually used for guided vertebroplasty and which allows the introduction of the Acufex hook blade atraumatically (foam end). The patient, under general anesthesia, is placed in supine position with the hip extending from 15 to 20°.
Study: NCT04781933

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Treatment with Combo
Description: Treatment with Combo

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Treatment with placebo
Description: Treatment with placebo
Study: NCT05363280

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL8326 low dose group
Description: Taken AL3826 at low dose orally
Study: NCT06000280

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Trabeculectomy surgery
Description: The Trabeculectomy aims to create a permanent drainage outflow channel for the aqueous humor, connecting the anterior chamber to the sub-Tenon's space, using mitomycin C consisted of opening the conjunctival base of the fornix and applying mitomycin C 0.4 mg/ml for 2 minutes. The trabeculectomy techniques require controlled outflow of aqueous humor through a sclerostomy and a partial-thickness scleral flap to form a subconjunctival bleb. The protected strength of the flap, with or without sutures, and the strength of the episcleral tissue determine the final IOP.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Trabeculectomy surgery
Description: The Trabeculectomy aims to create a permanent drainage outflow channel for the aqueous humor, connecting the anterior chamber to the sub-Tenon's space, using mitomycin C consisted of opening the conjunctival base of the fornix and applying mitomycin C 0.4 mg/ml for 2 minutes. The trabeculectomy techniques require controlled outflow of aqueous humor through a sclerostomy and a partial-thickness scleral flap to form a subconjunctival bleb. The protected strength of the flap, with or without sutures, and the strength of the episcleral tissue determine the final IOP.
Study: NCT05401942

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tele-monitoring through mobile application
Description: Tele-monitoring of Patient reported outcomes
Study: NCT04772638

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PLAY
Description: This intervention focuses on promoting physical activity in preschoolers and the adults (parents and teachers) in their lives. It consists of 1) Teacher training 2) Activity trackers for children, teachers and parents and 3) text messaging with content and individualized goal setting.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Wait list control
Description: not an active intervention
Study: NCT06292611

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Battery operated toothbrush
Description: Device on extrinsic stain removal efficacy

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual toothbrush
Description: Device on extrinsic stain removal efficacy
Study: NCT06251401

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In-person supervised cardiac rehabilitation
Description: In-person CR consists of weekly group-based supervised exercise training at Women's College Hospital, supplemented with home-based exercise training, with the goal of reaching Canadian Physical Activity Guidelines of 150 minutes a week of moderate-intensity exercise per week. Exercise prescriptions are individualized at baseline by the cardiac rehabilitation team. Both study arms get have the opportunity to attend weekly synchronous virtual group video education sessions for the duration of the 12-week cardiac rehab program with the focus on self-management education and support.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual cardiac rehabilitation
Description: Virtual CR consists of once-weekly telephone or video conferencing-based follow-ups (according to participant preference and access to internet/smart device) by one of the cardiac rehab providers. Similar to the in-person program, the virtual program also encourages participants to set goals to achieve 150 minutes a week of moderate-intensity exercise. The exercise prescription is individualized to each participant's ability and can vary in number of sessions per week and duration of each exercise session, as per the cardiac rehab provider's discretion. Unlike the in-person program, all these sessions are completed at home in an unsupervised manner. Both study arms get have the opportunity to attend weekly synchronous virtual group video education sessions for the duration of the 12-week cardiac rehab program with the focus on self-management education and support.