TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05212753

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Hot packs or hot water bags are superficial warming agents that will be used to heat muscle tissue, reduce muscle spasms and pain sensation. TENS is a pain reliever application.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Hot packs or hot water bags are superficial warming agents that will be used to heat muscle tissue, reduce muscle spasms and pain sensation. TENS is a pain reliever application.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Hot packs or hot water bags are superficial warming agents that will be used to heat muscle tissue, reduce muscle spasms and pain sensation. TENS is a pain reliever application.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lumbar stabilization exercises
Description: Training about the concepts of stabilization and abdominal bracing is given before starting the study. The motor control tests for local muscles transversus abdominus and multifidi are performed after the training. The abdominal bracing test is performed in the quadruped position, in prone, and in hook lying position with the patient's spine supine with hips and knees flexed and knees in contact with the surface. The second stage consists of closed-chain segmental control exercises. It is a series of weight-bearing exercises are performed on stable and unstable surfaces. The last stage of the stabilization program is an open kinetic chain exercise to promote distal stability.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lumbar stabilization exercises
Description: Training about the concepts of stabilization and abdominal bracing is given before starting the study. The motor control tests for local muscles transversus abdominus and multifidi are performed after the training. The abdominal bracing test is performed in the quadruped position, in prone, and in hook lying position with the patient's spine supine with hips and knees flexed and knees in contact with the surface. The second stage consists of closed-chain segmental control exercises. It is a series of weight-bearing exercises are performed on stable and unstable surfaces. The last stage of the stabilization program is an open kinetic chain exercise to promote distal stability.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Breathing exercises
Description: Breathing exercises consist of the techniques of diaphragmatic and pursed-lip breathing. During diaphragmatic breathing, attention is focused on the correct abdominal breathing. The pursed-lip breathing is one step further to the diaphragmatic breathing and a technique designed to have control time and volume over-breathing. This intervention also includes Sleep Hygiene education to the subjects,
Study: NCT05788692

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: electric tootbrush
Description: Participants will brush twice per day with an electric toothbrush

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: electric tootbrush
Description: Participants will brush twice per day with an electric toothbrush

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: manual toothbrush
Description: Participants will brush twice per day with a manual toothbrush

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: manual toothbrush
Description: Participants will brush twice per day with a manual toothbrush

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: toothbrushing assisting application
Description: Participants will brush twice per day with toothbrushing assisting application

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: toothbrushing assisting application
Description: Participants will brush twice per day with toothbrushing assisting application
Study: NCT05613153

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Peppermint Oil
Description: Participants weighing more than 40 kg will receive 2 peppermint oil capsules 3 times a day. Smaller children who weigh between 30 kg and 40 kg will receive 1 capsule of peppermint oil 3 times a day. All subjects will receive 8 weeks of treatment.
Study: NCT06227221

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sorafenib
Description: Subjects receive sorafenib 400mg once daily. Insulin therapy will be continued as a routine therapy.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects receive placebo 400mg once daily. Insulin therapy will be continued as a routine therapy.
Study: NCT04592159

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nabiximols
Description: oromucosal spray

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oromucosal spray
Study: NCT05573633

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ECG
Description: the POAF will be diagnosed using a 12-lead ECG and according to the usual monitoring protocols for patients in the cardiac surgery department of Amiens University Hospital.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: scanwatch
Description: POAF will be diagnosed with a Withings SM (ScanWatch). FAPO diagnosed by the SW will have to be confirmed by a 12-lead ECG.
Study: NCT05987254

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: suprainguinal fascia iliaca block
Description: ultrasound guided suprainguinal fascia iliaca block

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pericapsular nerve group block
Description: ultrasound guided pericapsular nerve group block
Study: NCT04626349

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FOCUS+ (face-to-face nurse-led intervention)
Description: Home-based psycho-educational intervention consisting of two 90-minute home visits and one 30-minute video-conferencing session, conducted by a trained intervention nurse over a period of 12 weeks (4 weeks between each session).~The intervention is comprehensively manualized and there is a protocol to guide delivery of the intervention for each home visit and video call. The content of the sessions is always tailored to the needs of the dyads, so certain topics can be discussed more in-depth and specific information can be shared. The nurses who will deliver the FOCUS+ intervention will receive an extensive online training and additional continuous follow-up training to provide them with the knowledge and skills required to successfully implement the intervention. A FOCUS+ core booklet is provided as a supporting guide for the dyads that they can refer to at their own discretion and reinforces key intervention messages linked to the core components of the intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: iFOCUS (web-based intervention)
Description: Self-managed psycho-educational intervention that is completed autonomously by the patient-caregiver dyads together. It encompasses four sessions (with three weeks between each session) over a period of 12 weeks.~The sessions are completed simultaneously by the patient and the family caregiver, sitting side by side at a computer. Patient-caregiver dyads have flexibility as to when they want to complete the intervention session. Based on the information patients and caregivers provided at enrollment and during the web-based sessions, they receive tailored individual and dyadic messages. An online personal workbook is provided containing the results of the interactive exercises that are provided to the dyads during the web-sessions. Any information brochures, leaflets and information sheets that the dyad indicated as 'of interest to them' during the web-sessions will be included as a hyperlink in their personal workbook.
Study: NCT06517264

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antibiotic
Description: antibiotic treatment, analgesics and hygienic-dietetic measures

Intervention type: OTHER
Group type: OTHER
Intervention: Non antibiotic
Description: Analgesics and hygienic-dietetic measures
Study: NCT05677607

Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance imaging
Description: Imaging diagnostics mainly based on Magnetic resonance imaging.
Study: NCT05445947

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The EASEL (Enhancing And Supporting Early Development to Better Children's Lives) Approach
Description: The EASEL Approach consists of a set of educator-led practices that can be incorporated into the daily classroom environment for children three to six years of age. The overall purpose of this approach is to enhance early childhood educators' teaching practices that would promote children's SEB+EF development.~Nine EASEL practices were selected for inclusion in the EASEL Approach. These are a) core fundamental practices that are evidence-based, b) practices that expert stakeholders identified as ones for which local early childhood educators may need additional training, c) practices that are not already covered in pre-service training to avoid replication for educators, d) a combination of practices that educators may already be implementing and can enhance, and new practices, and e) a balance of antecedent and consequential practices (i.e., practices that can be implemented before and after a target behavior).
Study: NCT05367700

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10382(Part 1: Dose escalation)
Description: Single or multiple dose(s) of HS-10382 once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10382(Part 2: Dose expansion)
Description: HS-10382 is administered orally once daily.
Study: NCT06035302

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Madany Closure
Description: Madany Closure is a new technique for the porte site closure

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard closure
Description: Standard closure technique of the port site from ecternal
Study: NCT04741594

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Densah
Description: Alveolar bone remodeling after tooth extraction may result in significant ridge resorption and inadequate bone volume for implant placement. Several methods have been designed for ridge augmentation, among which is the new technique of osseodensification, using the Densah® burs by Versah® (Versah®, LLC, Jackson, MI, USA). This method compresses the trabecular bone to periphery of the osteotomy site and has shown up to 80% ridge expansion in animal histological studies , , , , , . Apart from being an animal model with a short follow-up, another limitation of these studies is the lack of three-dimensional evaluation of the change in morphology of the ridge. Human clinical studies , , , , have reported similar results, but they do not evaluate if this bone volume is retained during osseointegration and loading periods. No standardization method or long-term evaluation of peri-implant health was reported.
Study: NCT04837339

Intervention type: OTHER
Group type: OTHER
Intervention: Collection of biological samples
Description: Blood sample, biopsies sample, hair sample.
Study: NCT05663905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ambroxol Hydrochloride
Description: IV ambroxol hydrochloride 30mg TDS as adjunct therapy to standard therapy for severe pneumonia in ICU for 14 days. Each dose of 30mg of ambroxol will be diluted in 50ml of NS/D5% to be given intravenously over an hour.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Therapy
Description: Standard therapy for severe pneumonia as per recommended in the ICU Management Protocols by Malaysian Society of Intensive Care (MSIC). This includes antibiotics stewardship and supportive therapy.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard Therapy
Description: Standard therapy for severe pneumonia as per recommended in the ICU Management Protocols by Malaysian Society of Intensive Care (MSIC). This includes antibiotics stewardship and supportive therapy.
Study: NCT05826145

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Vocal Expression
Description: There will be a total of 8 sessions. At baseline (week 0), only questionnaires will be completed. There will be 7 treatment sessions beginning at week 2, and the other sessions conducted at approximately every 3 weeks over the 6-month study duration where the vocal expression sessions will be provided.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral
Description: There will be 8 treatment sessions where part of the baseline session of session 1 (week 0) will include some instruction, session 2 will occur in week 2, and the other sessions conducted at approximately every 3 weeks over the 6-month study duration. Sessions will include various cognitive-behavioral techniques including completing a grief monitoring diary, imaginal revisiting, cognitive restructuring, describing positive memories of the deceased, and identifying future goals.
Study: NCT06502743

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nesuparib
Description: Nesuparib 150mg or 100mg, QD, PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nesuparib
Description: Nesuparib 150mg or 100mg, QD, PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab 400mg, IV, Q6W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab 400mg, IV, Q6W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab 400mg, IV, Q6W
Study: NCT06186869

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercise and diet intervention
Description: subjects randomized and assigned to one intervention group, will follow the low glycaemic index Mediterranean diet and simultaneously perform moderate-intensity aerobic exercises

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Hiit and diet intervention
Description: subjects randomised and assigned to one intervention group, will follow the low glycaemic index Mediterranean diet and simultaneously perform high-intensity interval exercises in the gym

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diet
Description: subjects randomised and assigned to this intervention group will follow the low-glycaemic index Mediterranean diet
Study: NCT06415604

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychoeducation
Description: The content of psychoeducation is based on Five Ways of Well-being which covers Be active, Connect, Take Notice, Keep learning and Giving.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Attention control
Description: The content of the sessions mainly focuses on physical health information, such as healthy eating, physical exercise, prevention of falls, and pain management.
Study: NCT06292442

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional physical therapy
Description: This group received conventional physical therapy treatment including Range of Motion (ROM) exercises for the affected hip, knee, and ankle joints, as well as stretching exercises for tight lower limb muscles, administered 3 times per week for 4 weeks, with each session lasting approximately 20-30 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High intensity interval training
Description: This group received High Intensity interval training along with conventional treatment for lower limb muscles, performed 3 times per week fr 4 weeks.
Study: NCT03674723

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary Intakes
Description: Four levels of methionine intakes will be provided by the reference protein drinks, 3 levels of methionine from Mung beans and 3 levels from Mung beans with rice or wheat.
Study: NCT05109208

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ulrasound Vibroelastography (UVE)
Description: Ultrasound technique to quantitatively assess tissue stiffness (elasticity and viscosity) by applying vibration through a specialized probe (indenter).
Study: NCT05887960

Intervention type: OTHER
Intervention: CBC and flow cytometry test for monocyte
Description: all groups assigned Cbc with leukocyte differential and flow cytometry for monocyte population

Intervention type: OTHER
Intervention: CBC and flow cytometry test for monocyte
Description: all groups assigned Cbc with leukocyte differential and flow cytometry for monocyte population

Intervention type: OTHER
Intervention: CBC and flow cytometry test for monocyte
Description: all groups assigned Cbc with leukocyte differential and flow cytometry for monocyte population
Study: NCT05365399

Intervention type: DEVICE
Group type: OTHER
Intervention: smartphone-based screening tool for neonatal jaundice
Description: In this study we aim to collect data of newborns with wider range of bilirubin levels and high melanin content, and additionally measurements of skin color reflectance with a spectrophotometer, to adjust the Picterus JP algorithm and optimize the app performance. This will enable a high qualitative estimation of bilirubin levels in the blood of new-borns for all skin colors. .
Study: NCT05794477

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SHR-1802
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SHR-1802
Description: Specified dose on specified days
Study: NCT05942521

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Very brief extinction
Description: The very brief extinction presents a very short (33ms) repetitive sequence of alcohol cues, followed by a masking stimulus(117ms), which masks the alcohol cues. In the case of repeated exposure to alcohol stimulation, the response to the stimulation is desensitized at the level of unconscious processing.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Clearly visible extinction
Description: The clearly visible extinction presents a repetitive sequence of alcohol cues(150ms) without a masking stimulus. In the case of repeat exposure to alcohol stimulation, the response to the stimulation is desensitized at the level of conscious processing.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Very brief neutral extinction
Description: The very brief neutral extinction presents a very short (33ms) repetitive sequence of neutral cues, followed by a masking stimulus(117ms), which masks the neutral cues. In the case of repeated exposure to neutral stimulation, the response to the stimulation is desensitized at the level of unconscious processing.
Study: NCT05538936

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baby SPA
Description: Salus Per Aquam, Sanitas Per Aquam, Salut Per Aqua or Solus Per Aqua (SPA) means health that comes with water. Baby SPA is a physiotherapy method that stimulates the baby's motor movements through water (hydrotherapy) and performs it in an integrated way to balance the body, mind, and emotions. Baby SPA is applied in specially designed bathtubs. The size of the tub is designed in such a way that children can move their hands and feet freely and not be narrow. A neck ring/ring is used to keep the baby on the water surface during SPA treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: The best way to communicate with a baby is to touch it. When babies are born, unlike their other senses, the most developed one is the sense of touch. Because this process begins while in the womb. The baby communicates by touch and begins to recognize his environment. The sense of touch is a priority for the development of all senses. They need to perceive their environment, especially in newborns and infancy periods. Touching the body in a systematic way for a therapeutic purpose is called Massage. Massage is soft touches to body tissues to relax muscles, accelerate circulation, reduce infantile colic symptoms and pain, regulate sleep, and increase its duration. Baby massage has many benefits such as reducing colic symptoms, increasing weight gain, providing motor development and coordination, strengthening the parent and baby bond, supporting growth and development, and reducing stress.
Study: NCT05794477

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SHR-1802
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SHR-1802
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SHR-1802
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin/Cisplatin
Description: Specified dose on specified days. Participant will receive only two of the listed chemotherapies (carboplatin, cisplatin, paclitaxel, nab-paclitaxel) along with immunotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin/Cisplatin
Description: Specified dose on specified days. Participant will receive only two of the listed chemotherapies (carboplatin, cisplatin, paclitaxel, nab-paclitaxel) along with immunotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel/Nab-Paclitaxel/Pemetrexed
Description: Specified dose on specified days. Participant will receive only two of the listed chemotherapies (carboplatin, cisplatin, paclitaxel, nab-paclitaxel) along with immunotherapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel/Nab-Paclitaxel/Pemetrexed
Description: Specified dose on specified days. Participant will receive only two of the listed chemotherapies (carboplatin, cisplatin, paclitaxel, nab-paclitaxel) along with immunotherapy.
Study: NCT05789225

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fall prevention program
Description: The intervention consists of the fall prevention program for ambulatory and non-ambulatory people with multiple sclerosis. The program is group-based with 8 participants in each group, led by a facilitator, and performed online. It comprises seven two-hour sessions held once a week, and a booster session held four weeks after the seventh session. In addition participants will receive a brochure about falls and fall risk factors.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Brochure
Description: Control-group participants will receive a brochure about fall risk factors and fall prevention in addition to the standard MS care and rehabilitation.