TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05481333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGN7999
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Ascending IV or SC dose administered per protocol
Study: NCT04347135

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: F-18 FES
Description: F-18 FES PET/MRI for detection of endometriosis.
Study: NCT06116812

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the laughter yoga group
Description: They will gather in five-person chemotherapy rooms, and laughter therapy will be applied to the women in the application group while they are receiving chemotherapy. Sessions will last approximately 40-60 minutes.The application will last for a total of 8 weeks, twice a week.~The 9th and 16th sessions will be held face to face and the scales will be filled in face to face meetings in these weeks (at the end of the 4th week and the 8th week). Since patients receive chemotherapy treatment once a month, face-to-face sessions are planned to be administered while the patient is receiving treatment. (Those whose treatment timing frequency is not appropriate will be excluded).~* Other sessions will be held online via smartphone applications. Online sessions will be determined according to the mutual decision of the participants, at a time convenient for the participants.~* In the 12th week, all groups will have the scales filled in again.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the mindfulness based stress reduction group
Description: Mindfulnes therapy will be applied to the women in the application group while they are receiving chemotherapy, in five-person chemotherapy rooms. Sessions will last approximately 40-60 minutes.The application will last for a total of 8 weeks, twice a week.~The 9th and 16th sessions will be held face to face and the scales will be filled in face to face meetings in these weeks (at the end of the 4th week and the 8th week). Since patients receive chemotherapy treatment once a month, face-to-face sessions are planned to be administered while the patient is receiving treatment. (Those whose treatment timing frequency is not appropriate will be excluded).~* Other sessions will be held online via smartphone applications. Online sessions will be determined according to the mutual decision of the participants, at a time convenient for the participants.~* In the 12th week, all groups will have the scales filled in again.
Study: NCT04034901

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Monitoring of cardiorespiratory parameters with BORA Band
Description: The subjects will continuously wear a connected wrist-worn pulse oximeter which will remotely collect the following measurements :~* Activity~* Step count~* Heart rate~* Respiratory rate~* Skin temperature~* SpO2
Study: NCT04769960

Intervention type: DIAGNOSTIC_TEST
Intervention: MRI Studies
Description: MRI scans will be performed on a 1.5T MRI scanner. Department of Radiology MRI SafetyGuidelines will be followed except regarding breast tissue expanders. Conventional MRIstudies will be performed using the standard of care clinical sequences.

Intervention type: BEHAVIORAL
Intervention: Patient Reported Outcomes
Description: Participants will fill out questionnaires before, immediately after, and approximately 3 months following the MRI examination +/- 1 month to evaluate for any pain or perceived changes with the breast tissue expander. The first questionnaire will obtain background participants information as well as establish a baseline pain level, the second questionnaire will evaluate any changes in pain after undergoing the MRI examination, and the last questionnaire will evaluate long term changes in pain. The patient reported outcome questionnaire will be optional at 3 months post-MRI +/-1 month.
Study: NCT05443321

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Information Exchange (HIE) platform
Description: An improved health information exchange (HIE) platform will be developed at the start of the study with key stakeholder input. This platform will be implemented for use after baseline data collection, and will allow for improved data exchange between transferring and accepting hospital. We will allow for a 6-month wash-in period prior to intervention data collection.
Study: NCT05428748

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1 serving of test product
Description: Participants will consume 1 serving/day of the test product for 28 days
Study: NCT06556069

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peer-Support Enhanced Agitation Code Team (PACT)
Description: PACT will address systems challenges experienced by staff, safety threats to ED patients with mental illness and substance use disorders, and known structural biases against marginalized individuals during decisions in use of restraints for behavioral crises in the ED.~The PACT intervention includes a peer support service component to deliver patient-centered, trauma-informed, culturally sensitive care to patients presenting with behavioral complaints in the ED and experiencing distress.
Study: NCT06530875

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: training on hesitations regarding childhood vaccinations
Description: Training will be given to expectant mothers on childhood vaccination hesitations
Study: NCT05428748

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 2 servings of test product
Description: Participants will consume 2 servings/day of the test product for 28 days

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3 servings of test product
Description: Participants will consume 3 servings/day of the test product for 28 days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will consume 1 serving/day of the placebo for 28 days
Study: NCT04868799

Intervention type: BIOLOGICAL
Intervention: Mass spectrometry
Description: Characterization of the proteomic and phosphoproteomic landscape using mass spectrometry
Study: NCT05292599

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental
Description: CCFE will be performed with the patient in a supine position with both knees flexed at 45°. This exercise involves a craniocervical movement. The IFE will be performed with the patient in a supine position while the IEE will be performed in a prone position. Both exercises will activate cervical muscles. RFE and RRE will be performed with the patient in a sitting or standing position at the same time he resists with his hands on his head. ME the function of these exercises is to depress and stabilize the scapula.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: CCFE will be performed with the patient in a supine position with both knees flexed at 45°. This exercise involves a craniocervical movement. The IFE will be performed with the patient in a supine position while the IEE will be performed in a prone position. Both exercises will activate cervical muscles. RFE and RRE will be performed with the patient in a sitting or standing position at the same time he resists with his hands on his head. ME the function of these exercises is to depress and stabilize the scapula.
Study: NCT04883762

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Fecal Microbiota Transplantation (FMT)
Description: Undergo FMT via colonoscopy.
Study: NCT04866823

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Medically Tailored Meals
Description: Participants will receive weekly meals (20 per week) prepared by a local community kitchen and catering group. Each week, 10 dinners and 10 lunches will be delivered to the participant's home with instructions for storage, re-heating, recipes, and nutritional information.
Study: NCT04696250

Intervention type: DRUG
Intervention: Antineoplastic and Immunomodulating Agents
Description: Antineoplastic agents, endocrine therapy, immunostimulants and immunosuppressants drugs included in the ATC classification L
Study: NCT06453356

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zavegepant 10mg
Description: intransal spray 10mg
Study: NCT06628505

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Speech in Noise Training
Description: The active controls will receive frequency discrimination training that uses the same visual landscape and basic task of controlling the wisp based on judgments about acoustic cues. The task requires participants to avoid obstacles by swiping upward or downward on the touchscreen to indicate whether a test frequency associated with the obstacle was higher or lower, respectively, than a target sound presented slightly before the test sound.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spatial Hearing Training Group
Description: Stimulus presentation and response measurement (Aim 2): Acoustic stimuli will be presented with a 360° speaker array that are fixed in place behind an opaque, nearly sound transparent, acoustic fabric curtain to avoid visual influences. Manual responses will be collected using a keyboard. Custom Matlab scripts control all relevant variables with millisecond precision. A webcam monitors the participant (not recorded) for the sole purpose of making sure the participant is always facing straight ahead.~Sound localization task and training: Participants will judge the location of a target white noise sound (1000 ms, 70 dB SLP, 10-10,000 Hz) by moving an auditory pointer that appears 2 seconds after the offset of the target sound.~The training group are given feedback about how their perceived location related to the actual sound location.

Intervention type: OTHER
Group type: OTHER
Intervention: Spatial Hearing Control Group
Description: Stimulus presentation and response measurement (Aim 2): Acoustic stimuli will be presented with a 360° speaker array that are fixed in place behind an opaque, nearly sound transparent, acoustic fabric curtain to avoid visual influences. Manual responses will be collected using a keyboard. Custom Matlab scripts control all relevant variables with millisecond precision. A webcam monitors the participant (not recorded) for the sole purpose of making sure the participant is always facing straight ahead.~Sound localization task and training: Participants will judge the location of a target white noise sound (1000 ms, 70 dB SLP, 10-10,000 Hz) by moving an auditory pointer that appears 2 seconds after the offset of the target sound.~The training group are NOT given feedback about how their perceived location related to the actual sound location.
Study: NCT06629896

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Contrast Enhancement Mammography
Description: In the experimental arm women will receive two rounds of CEM surveillance. After 2 years, all women who were randomly assigned to receive either MRI or CEM will undergo the same exit test. This exit test is the standard test used for the surveillance of high-risk non mutated women at each participating center.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: magnetic resonance imaging (MRI) and digital mammography (DM)
Description: women will receive two rounds of MRI+DM surveillance. After 2 years, all women who were randomly assigned to receive either MRI or CEM will undergo the same exit test. This exit test is the standard test used for the surveillance of high-risk nonmutated women at each participating center.
Study: NCT04936789

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IMES
Description: Surgical implantation of IMES
Study: NCT04749433

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [11C]CPPC Injection
Description: A single dose of \[11C\]CPPC (370 megabecquerel (MBq) (X±1 mCi)) intravenously and subsequent positron emission tomography (PET) scan.
Study: NCT05932511

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 30% ascorbic acid in DMSO
Description: see above
Study: NCT03840668

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: USB Eye Mask
Description: To evaluate the acceptance of the USB eye mask via questionnaire and also to monitor the use of USB eye mask over a period of 2 months.
Study: NCT06391073

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Measured Blood Pressure Monitoring
Description: Prompted SMBP with tailored feedback

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physician appointment and transportation scheduling
Description: Physician appointment and transportation scheduling or none dependent on current BP control
Study: NCT05474508

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diaphragmatic breathing
Description: Exercise programs will consist of 1 set of contractions per day and each set will include 30 repetitions for 6 weeks.
Study: NCT06212817

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: Increase dietary fiber intake

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention
Description: Increase dietary fiber intake
Study: NCT05003856

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiofrequency Ablation
Description: Undergo RFA
Study: NCT06270056

Intervention type: DRUG
Intervention: Misoprostol
Description: Self-administered misoprostol by clients obtaining medication abortion via telemedicine
Study: NCT05590351

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: First diet: m-health coaching application
Description: Intervention for the study would comprise of a culturally appropriate m-health application called first diet. This application will be developed considering the perceptions, barriers and facilitators identified through formative research. Content of the messages would focus on breastfeeding, its importance and early initiation within one hour of birth, significance of first feed i.e. colostrum, importance of EBF from birth till 6 months, introduction of complementary feeding to 6-8 months old infants and appropriate YCFP. These messages would be drafted in the local preferable language assessed during formative research. The content of the messages would be translated and then back translated to ensure validity. These messages will be short, contextual and tailored according to the women's stage of gestation, delivery and infant's age

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Face to Face counselling
Description: Women randomly enrolled in the non-interventional group will receive face-face nutritional counseling instead of mobile application. Once enrolled in the group, Research Assistant (RA) will collect relevant details on the baseline questionnaire like intervention group but on a paper-based questionnaire. Women will be given first face-face counseling on the day of enrollment. The counseling sessions will coincide with the routine vaccination and growth monitoring schedule of the infant after women deliver
Study: NCT05204485

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fibular intramedullary nail
Description: The standard manufacturers approved technique will be performed including the use of 2 distal interlocking screws and the use of a minimum of 1 fibula pro tibia fixation screw depending on the patients' anatomical characteristics.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open reduction and internal fixation
Description: An open approach (direct lateral or posterolateral incision) will be carried out. The reduction will be performed using standard techniques of clamping and traction. Fixation will be performed after reduction of the fracture with a plate and screw construct. The surgeon will then proceed to perform surgical fixation of other associated fractures or ligament injuries as indicated. This will most often include open reduction and internal fixation of the medial malleolus with screws through a separate medial incision.
Study: NCT06077357

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MMSE Test
Description: Mini Mental State Examination (MMSE), is a brief mental test used to assess individuals' cognitive functions. This test evaluates basic cognitive abilities such as memory, attention, calculation, language, orientation, and problem-solving. MMSE is commonly used for monitoring and assessing mild cognitive impairments, dementia, and other neurological conditions. This test is typically scored out of 30, with higher scores indicating better cognitive function.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MMSE Test
Description: Mini Mental State Examination (MMSE), is a brief mental test used to assess individuals' cognitive functions. This test evaluates basic cognitive abilities such as memory, attention, calculation, language, orientation, and problem-solving. MMSE is commonly used for monitoring and assessing mild cognitive impairments, dementia, and other neurological conditions. This test is typically scored out of 30, with higher scores indicating better cognitive function.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PASE Test
Description: The PASE test stands for Physical Activity Scale for the Elderly. This scale is used to assess the physical activities undertaken by elderly individuals in their daily lives. The PASE test allows for the evaluation of both daily activities such as walking, climbing stairs, and household chores, as well as exercise routines. It is used to determine the level of physical activity in elderly individuals and support the process of healthy aging.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PASE Test
Description: The PASE test stands for Physical Activity Scale for the Elderly. This scale is used to assess the physical activities undertaken by elderly individuals in their daily lives. The PASE test allows for the evaluation of both daily activities such as walking, climbing stairs, and household chores, as well as exercise routines. It is used to determine the level of physical activity in elderly individuals and support the process of healthy aging.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The PRISMA-7 Frailty Scale
Description: The PRISMA-7 Frailty Scale is a tool used to assess the level of frailty in elderly individuals. This scale evaluates signs of frailty such as physical activity, fatigue, weight loss, and difficulties with vision and hearing. PRISMA-7 is employed in determining the risk of frailty in the elderly and aids in identifying appropriate treatment and support methods.
Study: NCT05403788

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intervention with virtual reality
Description: VR intervention with OCULUS QUEST2 (OCULUS VR, USA) consiste on a VR helmet positioned over subject head. The software consisted of a 3D environment with exercises of upper limbs and visual feedback for the treatment of cognitive and motor dysfunction. The therapist have real-time access to the activities in the 3D environment vby real-time video transmission of the helmet activity.~The program include a single session. Each session is monitored on safety aspects of the subjects with emphasis on possible side effects of virtual reality.
Study: NCT05464693

Intervention type: DIAGNOSTIC_TEST
Intervention: ERCP biliary culture
Description: The sample of biliary aspirate will be assessed as follows.~1. Its macroscopic appearance will be analyzed: yellow, black, or purulent.~2. Biliary culture will be performed; if bacterial growth is observed, its identification will be carried out by means of MALDI-TOF MS mass spectrometry and antibiotic susceptibility tests will be carried out, using the automated VITEK system.
Study: NCT06629571

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: Training for the patient before surgery
Study: NCT05541042

Intervention type: OTHER
Intervention: Observational only
Description: This is an observational study
Study: NCT04599946

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Infant formula and follow-on formula made from whole goat milk
Description: Infant formula and follow-on formula made from whole goat milk

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Infant formula and follow-on formula made from cow's milk ingredients
Description: Infant formula and follow-on formula made from cow's milk ingredients
Study: NCT05815641

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: food (breakfast)
Description: The breakfast composition is 56 kcal% carbohydrates, 12 kcal% protein and 34 kcal% lipids and comprises yogurt, cereals and almonds
Study: NCT06077357

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The PRISMA-7 Frailty Scale
Description: The PRISMA-7 Frailty Scale is a tool used to assess the level of frailty in elderly individuals. This scale evaluates signs of frailty such as physical activity, fatigue, weight loss, and difficulties with vision and hearing. PRISMA-7 is employed in determining the risk of frailty in the elderly and aids in identifying appropriate treatment and support methods.
Study: NCT05395689

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: House dust mites allergoid from Dermatophagoides pteronyssinus and Dermatophagoides farinae
Description: The vaccine will be administered according to a rush schedule meaning one administration each month for 1 year