TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05156502

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fractionated Laser (Pixel CO2-Alma)
Description: The Laser will be administered at baseline (visit 2, day 0), at visit 3 (day 28) and at visit 4 (day 56) into vagina and vestibule, following the IFU of the device.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fractionated Laser (Pixel CO.2-Alma)
Description: Device: Fractionated Laser (Pixel CO2-Alma) The Laser will be administered at baseline (visit 2, day 0), at visit 3 (day 28) and at visit 4 (day 56) into vagina only, following the IFU of the device.
Study: NCT05995301

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine in Transversus abdominis plane
Description: This group received 20ml of Ropivacaine 0.2% Injectable Solution in bilateral transversus abdominis plane at the end of surgery

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine in Local infiltration at port site
Description: This group received local infiltration of 20ml of Ropivacaine 0.2% Injectable Solutionat port sites at the end of surgery
Study: NCT04466215

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Miricorilant
Description: 900 mg (6 x 150 mg) tablets taken orally once daily for two weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: Six placebo tablets taken orally once daily for two weeks
Study: NCT05089435

Intervention type: DEVICE
Group type: OTHER
Intervention: EZYPRO® ECG Recorder
Description: EZYPRO is an ECG monitoring patch designed to enhance the arrhythmia detection rate by applying 14 days in a home setting environment.
Study: NCT06437093

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEACHING RELACTATION TECHNIQUES
Description: In our midwifery intervention, the mother was firstly educated about breastfeeding and relactation, using educational brochures prepared by the researchers. Afterwards, the mother was taught nipple stimulation, skin-to-skin contact and finger feeding method, and the first feeding of the baby was performed together with the mother. After this first intervention in the FHC, all interventions were performed at home. The follow-ups continued for 15 days with one day of telephone support and one day of home visit. Since the majority of mothers did not accept video calls (privacy, etc.), telephone support was provided only verbally.
Study: NCT06674655

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic Exercise
Description: This group will perform a lumbo-pelvic motor control exercise program for three consecutive days.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Minimal intervention
Description: This group will carry out a therapeutic counseling and minimal education intervention during a one-day intervention.
Study: NCT06621758

Intervention type: OTHER
Intervention: questionnaire
Description: Questionnaire regarding biomarker counseling and diagnostic disclosure

Intervention type: OTHER
Intervention: questionnaire
Description: Questionnaire regarding biomarker counseling and diagnostic disclosure
Study: NCT06017830

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Physical treatment agents
Description: Physical treatment agents such as TENS (transcutaneous electric nerve stimulation), hot pack and ultrasound will be applied to patients with low back pain. Sexual function will be assessed before, just after and 3 months later physical therapy.
Study: NCT05984316

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Dual task exercises are defined as the appropriate direction of attention during two activities performed at the same time. Dual task performance is required during many activities in daily life. Multitasking is complicated to understand because it is divided into social, physical, and psychological branches.~The simultaneous occurrence of movement and cognitive processes is seen as a part of social participation. Considering that one task affects the other, dual task is defined as the simultaneous performance of two tasks that can be performed independently, can be evaluated separately, and have different purposes.~Each task must be incompatible and measurable, achievable alone or in different combinations. The increased need for information processing alone does not constitute dual-tasking.
Study: NCT04871035

Intervention type: DEVICE
Intervention: Immunoadsorption
Description: 1 cycle, consisting of 5 sessions on 5 consecutive days with processing of the 0.7-fold individual plasma volume (maximum 2.5 l) each days with tryptophan adsorbers.

Intervention type: DEVICE
Intervention: Plasma Exchange
Description: 1 cycle, consisting of 5 sessions on 5 consecutive days with exchange of 0.7-fold plasma volume (maximum 2.5 l) each day with albumin solution as volume replacement solution.
Study: NCT05720234

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: avatrombopag
Description: Patients with body weight ≥50kg were given 60mg/day and patients with body weight \< 50kg were given 40mg/day for 12 weeks.
Study: NCT04821635

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rower assisted by electrostimulation (FES-ROW)
Description: 1. Pre-inclusion visit~2. Inclusion visit~3. Phase 1 Rower-FES with lower limbs (Month 0 to Month 3: M0-M3):~   Training on a rower with solicitation of the electrostimulated lower limbs only for a period of 3 months at the rate of 3 sessions of 30 minutes per week~4. Interim assessment visit at Month 3 (M3)~5. Phase 2 Rower-FES with lower limbs + upper limbs (Month 3 to Month 6: M0-M6):~   Training on with solicitation of the electrostimulated lower and upper limbs for a period of 3 months at the rate of 3 sessions of 30 minutes per week~6. Final assessment visit at Month 6 (M6)~7. End of clinical research visit, 3 months after the end of training (Month 9, M9)
Study: NCT05348967

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: TECADRIOL
Description: Food supplement with D-chiro-inositol and alpha-lactalbumin
Study: NCT05904223

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Respiratory Panel PCR Sputum
Description: Multiplex PCR Respiratory Panel from Biomerieux used on Patients Sputum
Study: NCT05958498

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: injectable platelet rich fibrin and microosteoperforation
Description: i-PRF which second product of blood versus mops which is surgical procedure

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: injectable platelet rich fibrin and microosteoperforation
Description: i-PRF which second product of blood versus mops which is surgical procedure
Study: NCT05556317

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistive exercise
Description: advices and resistive exercise

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Resistive exercise
Description: advices and resistive exercise
Study: NCT04667013

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tetramethylpyrazine nitrone (TBN) tablet / Placebo
Description: Subjects will be administered multiple oral doses of TBN or matching placebo tablets twice a day for 6 consecutive days and a last dose in the morning of Day 7.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tetramethylpyrazine nitrone (TBN) tablet / Placebo
Description: Subjects will be administered multiple oral doses of TBN or matching placebo tablets twice a day for 6 consecutive days and a last dose in the morning of Day 7.
Study: NCT06053554

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Phakoemulsification
Description: Femtolaser is used to perform a standard 5.0mm CCC centred on the pupil or limbus and to fragment the lens nucleus toguarantee reproducible results in every eye.After the CCC and nucleus fragmentation the anterior segment is filled with viscoelastics, the rhexis lenticule is removed and hydrodisection of the nucleus is performed. Subsequently phacoemulsification for nucleus and irrigation/aspiration of the lens cortex is performed. The capsular bag and AC is then filled with a cohesive viscoelastic and the IOL is implanted with the haptics in the back or with the haptics in the sulcus. At the end of surgery, the viscoelastic is removed using the irrigation aspiration probe, intracameral antibiotic is instilled, the CCI and paracenteses are hydrated and sealed.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Phakoemulsification
Description: Femtolaser is used to perform a standard 5.0mm CCC centred on the pupil or limbus and to fragment the lens nucleus toguarantee reproducible results in every eye.After the CCC and nucleus fragmentation the anterior segment is filled with viscoelastics, the rhexis lenticule is removed and hydrodisection of the nucleus is performed. Subsequently phacoemulsification for nucleus and irrigation/aspiration of the lens cortex is performed. The capsular bag and AC is then filled with a cohesive viscoelastic and the IOL is implanted with the haptics in the back or with the haptics in the sulcus. At the end of surgery, the viscoelastic is removed using the irrigation aspiration probe, intracameral antibiotic is instilled, the CCI and paracenteses are hydrated and sealed.

Intervention type: DEVICE
Group type: OTHER
Intervention: Ziemer Z8 Femtolaser
Description: The femto second laser used for certain steps (capsulorhexis, nucleus fragmentation) of the cataract surgery.

Intervention type: DEVICE
Group type: OTHER
Intervention: Ziemer Z8 Femtolaser
Description: The femto second laser used for certain steps (capsulorhexis, nucleus fragmentation) of the cataract surgery.

Intervention type: DEVICE
Group type: OTHER
Intervention: Kowa Avansee Preset
Description: The used 3 piece intra ocular lens

Intervention type: DEVICE
Group type: OTHER
Intervention: Kowa Avansee Preset
Description: The used 3 piece intra ocular lens
Study: NCT06622850

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupressure
Description: In acupressure, cun is used as the unit of measurement to determine the points to be applied. In order to find the acupressure points correctly, measurements should be made using the individual\&#39;s own fingers. The thumb widths of the individuals participating in the study will be measured and converted as centimeter 1 cun unit. The points to be used in acupressure will be Shen Men (HT7) located in the transverse wrist crease, in the small depression between the pisiform and ulna bones, (LI11) located at the end of the crease when the elbow is bent, and Hegu (LI4) located in the space between the thumb and index finger will be marked by the certified researcher (GB) with an acetate pen in the patients in the study group. And the application will be performed by the certified researcher (GB).
Study: NCT06623123

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oto Smartphone Application (Oto Health Ltd)
Description: The smartphone application delivers personalized tinnitus therapy combining evidence-based CBT with mindfulness, patient education as well as physical therapy such as stretches and exercises. There are additional sounds available to listen to from the sound library. There will be a structured programme that the participants can work through however they are encouraged to personalise their own therapy.
Study: NCT05996952

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48-ADC
Description: Patients are treated with RC48-ADC at 2.0 mg/kg as an intravenous infusion over 30-90 minutes (60 minutes is recommended) once every 2 weeks for 12 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48-ADC
Description: Patients are treated with RC48-ADC at 2.0 mg/kg as an intravenous infusion over 30-90 minutes (60 minutes is recommended) once every 2 weeks for 12 weeks.
Study: NCT05778721

Intervention type: OTHER
Intervention: respond to questionnaires by telephone
Description: Seasonal Pattern Assessment Questionnaire (SPAQ) questionnaires and Sachs bipolarity index and Idiopathic Hypersomnia (IH) severity score
Study: NCT05835297

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical exercise interventions
Description: Participants will undergo a 12-week multicomponent exercise regimen, twice per week on non-consecutive days for 45-60 min each. The session will be divided into 4 min of warm-up; range of motion exercises of upper and lower extremities, followed by light walking, then 8 min balance exercises, followed by 15 min strength exercises; two sets of 13-15 repetitions maximum of chair rises with progression, two sets of 13-15 repetitions of modified squats (holding a chair backrest if needed) with progression, 2 sets of 20-30 repetitions of seated or 2 sets of 13-15 repetitions of standing calf raises, then 15 min aerobic exercises; five 3-min bouts of walking between two strengthening exercises and/or 2 balance exercises, finally 3 min cool down exercises of light walking and stretching exercises.
Study: NCT06623123

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tinnitus Retraining Therapy (TRT)
Description: Tinnitus-retraining therapy will be offered in the control arm which represents the standard evidence-based intervention on the NHS. (2) Participants enrolled to this arm will undertake tinnitus retraining therapy with a trained audiologist. The sessions will last 30 minutes with the option for further sessions should the patient which to have more support with their tinnitus to mimic the NHS programme as much as possible. These sessions will encompass a brief audiological history followed by therapy tailored to the patient's needs allowing for patient-centred optimisation of tinnitus burden and secondary comorbidities. This may include relaxation, CBT and advice surrounding sound as well as white noise masking therapy.
Study: NCT06667934

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zuoqing powder was dissolved in 100ml normal saline, retained enema, once a night
Description: Zuoqing powder was dissolved in 100ml normal saline, retained enema, once a night

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methalazine suppository was given rectally once a day
Description: Methalazine suppository was given rectally once a day
Study: NCT06598462

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Solrikitug Low Dose
Description: Solrikitug low dose subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Solrikitug Mid Dose
Description: Solrikitug mid dose subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Solrikitug High Dose
Description: Solrikitug high dose subcutaneous injection

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo subcutaneous injection
Study: NCT06675435

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nitric oxide
Description: 20ppm for 15 minutes delivered by INO max(Nitric Oxide) Company : INO therapeutics, Inc.
Study: NCT06683105

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MyIBDDiet app
Description: Participants in the Standard of Care arm will be administered the intervention (using the app) for 30 days, and participants in the MYIBDDiet arm will use the app for 60 days.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MyIBDDiet app
Description: Participants in the Standard of Care arm will be administered the intervention (using the app) for 30 days, and participants in the MYIBDDiet arm will use the app for 60 days.
Study: NCT06683833

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Egyptian MTA
Description: * Complete caries removal from the cavity.~* The liquid of Egyptian MTA (Toothmate) will be mixed with powder according to the manufacturers' instructions.~* The capping materials will be placed with the passive application on the deepest part of the cavity. Only light pressure will be applied on the MTA mixture using a wet cotton pellet to ensure adaptation of the material onto the dentin.~* A light-cured glass ionomer cement base will be applied in the cavity .~* Selective enamel etching will be applied on enamel only.~* The one-bottle universal adhesive system bond will be applied on enamel and dentine.~* A Nano hybrid composite resin material will then be incrementally inserted into the cavities.
Study: NCT04052191

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MCRcI® stem cells
Description: Intra-Coronary Administration of MCRcI® stem cells

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MCRcI® stem cells
Description: Intra-Coronary Administration of MCRcI® stem cells

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MCRcI® stem cells
Description: Intra-Coronary Administration of MCRcI® stem cells
Study: NCT06335199

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Unilateral tVNS stimulation
Description: Electrical stimulation to the cymba concha or tragus (depending on the ear dimension) of the outer ear on the left side after successful trials.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bilateral tVNS stimulation
Description: Electrical stimulation to the cymba concha or tragus (depending on the ear dimension) of the outer ear on both sides after successful trials.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Unilateral Sham stimulation
Description: Electrical stimulation to the earlobe of the outer ear on the left side after successful trials.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Bilateral Sham stimulation
Description: Electrical stimulation to the earlobe of the outer ear on both sides after successful trials.
Study: NCT06550349

Intervention type: OTHER
Intervention: N/A - non-interventional study
Description: N/A - non-interventional study. Data collection only.
Study: NCT05156281

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remibrutinib
Description: tablet taken orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remibrutinib
Description: tablet taken orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remibrutinib
Description: tablet taken orally

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Teriflunomide
Description: capsule taken orally
Study: NCT05953259

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Combination of STERN FIX and wires
Description: Closure of the median sternotomy using a combination of at least one STERN FIX device and wires for a total of 5 fixation points.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Wires
Description: Closure of the median sternotomy using the standard of care with steel wires.
Study: NCT06683833

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Biodentine
Description: * Complete caries removal from the cavity.~* Gently tapping a capsule of Biodentine (Septodont) on a hard surface to loosen the powder, then opening the capsule, Detaching a single-dose container of liquid and gently tapping on the sealed cap to force all the liquid down the container, Twisting cap to open, Then Pouring 5 drops from the single-dose container into the capsule, Then Closing the capsule and Placing it on a mixing device for 30 seconds, Then Collecting Biodentine with the instrument supplied in the box.~* The capping materials will be placed with the passive application on the deepest part of the cavity.~* A light-cured glass ionomer cement base will be applied in the cavity .~* Selective enamel etching will be applied on enamel only.~* The one-bottle universal adhesive system bond will be applied on enamel and dentine.~* A Nano hybrid composite resin material will then be incrementally inserted into the cavities.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcium Hydroxide (Ca(OH)2)
Description: * Complete caries removal from the cavity.~* According to the manufacturers' instructions, Dispensing equal volumes of base and catalyst pastes on the parchment paper pad provided. Using a Dycal (Dentsply) Liner applicator, stirring immediately to mix thoroughly until a uniform color is achieved, complete mixing occurs within 10 seconds, using the ball-pointed Dycal Liner applicator or similar instrument, the mix will be placed directly on the cavity.~* The capping materials will be placed with the passive application on the deepest part of the cavity.~* A light-cured glass ionomer cement base will be applied in the cavity .~* Selective enamel etching will be applied on enamel only.~* The one-bottle universal adhesive system bond will be applied on enamel and dentine.~* A Nano hybrid composite resin material will then be incrementally inserted into the cavities.
Study: NCT06682819

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Optical coherent tomography
Description: We compare the metabolomics profile of healthy patients based on the OCT appearance of the optic disc and RNFL
Study: NCT06685419

Intervention type: OTHER
Intervention: Propolis containing gum
Description: Patients with moderate gingivitis will be asked to use gum containing propolis 5 times a day for a total of 3 weeks.
Study: NCT06684561

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PIS
Description: All subjects will be instructed to change the investigational infusion sets (PIS) every 246 hours (10 days \& 6 hours) or at set failure. Each subject is required to wear the CGM device continuously.~defined as any one of the following: After completing 2 sets, the subjects have an optional office visit to download pump and CGM data and will continue to additional two wears. At day 40 or after using 4 completed wears of infusion sets (Note: early infusion set failure with wear time of \<6 hours due to insertion failure will be reported, yet not accounted as completed wear), the patients will return to a visit, download pump and CGM data, and end the study.~if study 1 is successful, participants will enter study 2; , the same study designed will be performed on the current on-market Extended infusion set (EIS) for comparison of clinical performance with the PIS, using the same cohort of pump users
Study: NCT06682377

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation alone
Description: No touch RFA with dual switching monopolar + bipolar mode
Study: NCT06682767

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: FMD1 (LNT22-017-1)
Description: FMD is a plant-based ketogenic diet that provides essential nutrients while maintaining hypo-caloric content. FMD is administered cyclically with 3-5 consecutive days of the diet followed by resumption of normal eating.