TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04976452

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multi-component teaching content
Description: The students assigned to Group 1 will undergo interactive module training by the American Medical Association which outlines how to properly measure blood pressure manually following the American Heart Association guidelines. Following completion of the module, students will be presented with a powerpoint lecture by the Primary Investigator on Blood Pressure. Students will then undergo a competency examination that assesses their ability to measure blood pressure following the guidelines of the American Heart Association.
Study: NCT05422092

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Canagliflozin
Description: 40 patients with T2DM combined with NAFLD, who have poor glycemic control response to metformin monotherapy, will be randomly assigned to receive canagliflozin on top of metformin as experimental group.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pioglitazone
Description: 40 patients with T2DM combined with NAFLD, who have poor glycemic control response to metformin monotherapy, will be randomly assigned to receive pioglitazone 45mg on top of metformin as placebo comparator group.
Study: NCT05674448

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HH-003 20mg/kg
Description: HH-003 20mg/kg Q2W intravenously for 24 weeks

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HH-003 3mg/kg
Description: HH-003 3mg/kg Q2W intravenously for 24 weeks
Study: NCT05365113

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: alveolar recruitment maneuver
Description: When patient is under general anesthesia, an arterial catheter is placed for cardiac output and stroke volume (SV) monitoring. To avoid pre-load dependency bias, the blood volume will be optimized. A 250mL fluid-challenge of a balanced crystalloid solution is administered under cover of the SV monitoring. If SV variation is greater than 10%, a new fluid-challenge is performed to obtain a reference SV, corresponding to the patient's optimal blood volume.The patient is then pre-load independent.~Then, patients will be randomized into two groups: a first group will receive a CPAP ARM: 40 cmH2O for 50 seconds, followed by a 10-minute break corresponding to a period of return to basal state; then an extended sigh ARM (e-sigh) also lasting 50seconds (driving pressure: 10cmH2O and successive PEEP levels at 10,15,20,25 and 30cmH2O, a respiratory rate set at 30/min in controlled pressure - 5cycles at each PEEP level); a second group will receive the same two ARM modalities in reverse order.
Study: NCT06407622

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Foot Reflexology
Description: In previous studies, no study was found investigating the effect of foot reflexology on sleep quality and bowel functions in patients undergoing surgical intervention. This study is thought to be the first to evaluate the effect of foot reflexology on sleep quality and bowel functions in surgical patients. In this respect, it is a study that will contribute to the literature.
Study: NCT06034119

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Split belt treadmill
Description: Participants will walk on a dual belt treadmill with each belt moving at a different speed which is known as a split belt treadmill to provide implicit modifications of the walking pattern

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Split belt treadmill
Description: Participants will walk on a dual belt treadmill with each belt moving at a different speed which is known as a split belt treadmill to provide implicit modifications of the walking pattern

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Biofeedback
Description: The Gait Real-time Analysis Interactive Lab (GRAIL) system has an immersive virtual reality screen that provides real-time information to participants of their walking pattern and provides visual instructions on how to walk more symmetrically

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biofeedback
Description: The Gait Real-time Analysis Interactive Lab (GRAIL) system has an immersive virtual reality screen that provides real-time information to participants of their walking pattern and provides visual instructions on how to walk more symmetrically
Study: NCT06161103

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 3D Printed Prefabricated Composite Resin Crown Group
Description: 3D Crown application: After preparing the molars, the crown was cemented by passive seating with modified glass ionomer cement (GC FujiCEM Evolve, GC America, Alsip, USA).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Prefabricated stainless steel crown group
Description: Stainless steel crown application: After preparing the molars, the crown was filled with type-1 glass ionomer cement (Aqua Meron, Voco, Cuxhaven, Germany) and cemented.
Study: NCT05502224

Intervention type: OTHER
Group type: OTHER
Intervention: Ergospirometry
Description: Maximum aerobic capacity (VO2 max), Maximum load, Ventilatory threshold and the patient's RQ
Study: NCT04725630

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy food incentive
Description: $10.50/week/household member for 12 months to purchase healthy foods in participating supermarkets.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy food prescription
Description: A one-time healthy food prescription pamphlet

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy food prescription
Description: A one-time healthy food prescription pamphlet
Study: NCT06441097

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Polatuzumab vedotin
Description: Polatuzumab vedotin IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Polatuzumab vedotin
Description: Polatuzumab vedotin IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: Rituximab IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide
Description: Cyclophosphamide IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Cyclophosphamide IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin
Description: Doxorubicin IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Doxorubicin IV infusion will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisone
Description: Prednisone PO will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone PO will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Acalabrutinib PO will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide PO will be administered as per the schedule specified in the respective arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine
Description: Decitabine IV infusion will be administered as per the schedule specified in the respective arm.
Study: NCT05645367

Intervention type: OTHER
Intervention: No intervention
Description: This is a post-hoc analysis of a cross-sectional study.

Intervention type: OTHER
Intervention: No intervention
Description: This is a post-hoc analysis of a cross-sectional study.
Study: NCT05114447

Intervention type: OTHER
Intervention: Routine medical care
Description: Eligible subjects will be contacted from physicians, by telephone or directly when they attend the clinical centre for control visits. Once the patients have provided their signed informed consent, they will have to fill in the clinical form and to perform routine functional/clinical tests.~Subjects will be investigated at baseline (T0), at 6-month follow-up (T6) and at 12-month follow-up (T12).~All the possible variations that could occur in the patients' disease status and disease management, according to the routine medical care, will be registered and taken into account in the RISER study.~RISER study is not a clinical trial, but it is an observational study without any specific drug administration by the investigators. Participants will receive interventions, which can include medical products, such as drugs or devices, or procedures, as part of their routine medical care but they will not be assigned to specific interventions by the investigator as in a clinical trial.

Intervention type: OTHER
Intervention: Routine medical care
Description: Eligible subjects will be contacted from physicians, by telephone or directly when they attend the clinical centre for control visits. Once the patients have provided their signed informed consent, they will have to fill in the clinical form and to perform routine functional/clinical tests.~Subjects will be investigated at baseline (T0), at 6-month follow-up (T6) and at 12-month follow-up (T12).~All the possible variations that could occur in the patients' disease status and disease management, according to the routine medical care, will be registered and taken into account in the RISER study.~RISER study is not a clinical trial, but it is an observational study without any specific drug administration by the investigators. Participants will receive interventions, which can include medical products, such as drugs or devices, or procedures, as part of their routine medical care but they will not be assigned to specific interventions by the investigator as in a clinical trial.

Intervention type: OTHER
Intervention: Telephone interview
Description: Eligible subjects will be contacted by telephone from trained personnel of the Research Unit. Once the signed informed consent is obtained by each enrolled subject, they will be invited to answer the phone questionnaire.~Subjects will be investigated at baseline (T0) and at 12-month follow-up (T12). Subjects fitting the epidemiological definition of severe/uncontrolled asthma will be invited at the Pisa clinical centre to have routine clinical/functional tests.~Each subject performing baseline clinical/functional tests at the Pisa clinical centre will be clinically and functionally re-assessed
Study: NCT05658783

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hot water foot bath
Description: Keeping keep in 42oC (42 Degrees Celsius) hot water for 20 minutes
Study: NCT06206746

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: May Health System
Description: The intervention includes the short-term use of the May Health System, which is comprised of three elements: (1) the May Health Needle-Catheter Ablation Device (NCAD) (the Device) a 16 gauge echogenic needle including a bipolar temperature-controlled RF ablation catheter which is clipped and secured onto a vaginal ultrasound probe; (2) the May Health Adapter which is clipped onto the ultrasound probe; and (3) the May Health Generator: a bipolar radiofrequency (RF) ablation platform utilizing the single use May Health NCAD for ovarian tissue ablation. Once the patient is under conscious sedation, the physician guides the May Health system transvaginally with the use of a transvaginal ultrasound. Once the May Health device is safely and securely positioned, the physician will deliver radio frequency energy inside the ovary in order to ablate the tissue.
Study: NCT05183620

Intervention type: DEVICE
Group type: OTHER
Intervention: Feeling Hot sensor system
Description: The Feeling Hot sensor system consists of two temperature probes placed on the penis and the outer thigh of the test subject to measure skin temperature during erection
Study: NCT06254781

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Luspatercept
Description: Erythroid Maturation Agent
Study: NCT04976257

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Angiogram
Description: Undergo angiogram
Study: NCT02974556

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard surgical treatment
Description: Standard surgical treatment (open or laparoscopic techniques) containing at least 12 lymph-nodes for accurate pN staging.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Proactive management
Description: Colon cancer patients (high-risk T3 and T4) without peritoneal or systemic metastases are resected for cure. Simultaneously patients will undergo infracolic omentectomy, appendectomy, exeresis of the liver round ligament and, in women, a bilateral oophorectomy. After positioning three in- and outflow catheters HIPEC perfusion starts with a minimum of 2 L isotonic dialysis fluid at a flow-rate of 1-2 l min and an inflow temperature of 42-43° C with a total of 30 minutes perfusion time. Before the beginning of HIPEC 5-fluouracil and leucovorin will be administrated intravenously to potentiate oxaliplatin activity.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard adjuvant systemic chemotherapy
Description: Adjuvant systemic chemotherapy (according CAPOX or FOLFOX regimens for a total of 6 months) will be reserved in patients with pT3 tumors with poor prognostic factors, in patients with pT4 tumors and when lymph-nodes metastases are present. Presence or absence of peritoneal recurrence will be evaluated by MDCT every six months for the first 24 months and later every year for the next three years in both study arms.
Study: NCT04976257

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Catheterization
Description: Undergo prostatic arterial catheterization

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gallium Ga-labeled PSMA-11
Description: Given IV and IA

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET scan
Study: NCT04892407

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Algeness® DF 3.5%
Description: dermal filler CE Mark approved for treatment of cheek and midface volume loss

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Juvéderm Voluma
Description: dermal filler CE Mark approved for treatment of cheek and midface volume loss
Study: NCT02974556

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard adjuvant systemic chemotherapy
Description: Adjuvant systemic chemotherapy (according CAPOX or FOLFOX regimens for a total of 6 months) will be reserved in patients with pT3 tumors with poor prognostic factors, in patients with pT4 tumors and when lymph-nodes metastases are present. Presence or absence of peritoneal recurrence will be evaluated by MDCT every six months for the first 24 months and later every year for the next three years in both study arms.
Study: NCT06454539

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional Inspiratory Muscle Training
Description: Functional IMT is an inspiratory muscle training that ensures core stabilization and maintains postural control. Rhythmic co-contractions of the core muscle areas (diaphragm, transversus abdominis, multifidus, pelvic floor) ensure the stability of the trunk and provide it with the feature of being the support point of movement. In the first stage, the person is given core stabilization training. Secondly, core stabilization is maintained and continued with strong trunk activation exercises. Postural exercises reinforce the other function of the breathing muscles, which is actually 'core' stabilization.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Inspiratory Muscle Training
Description: Inspiratory muscle training (IMT) is one of the methods used to increase respiratory muscle strength. Different tools and methods (threshold resistive loading, normocapnic hyperpnea, and threshold pressure loading) have been developed for IMI. The most used method in the literature is the threshold pressure loading method. This method requires subjects to generate a negative pressure sufficient to overcome the load of the device and thus initiate inspiration. ICE is most commonly performed in a sitting position, with upper extremities supported and upper chest/shoulders relaxed. By placing the person in this position, the aim is for the respiratory muscles to focus only on the work of breathing.
Study: NCT04970082

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: FFR DWP
Description: FFR will be measured twice in the same lesion : One with the standard method and the other with the DWP method.
Study: NCT05151341

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Urine collection (150ml)
Description: Urine collection will be tacken at inclusion. The sample will be thereafter separate into three to realise different analyzes (standard cytology, Visiocyt test, FGFR3 analysis)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Urine collection (150ml)
Description: Urine collection will be tacken at inclusion. The sample will be thereafter separate into three to realise different analyzes (standard cytology, Visiocyt test, FGFR3 analysis)
Study: NCT04970082

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: FFR DWP
Description: FFR will be measured twice in the same lesion : One with the standard method and the other with the DWP method.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: FFR
Description: FFR will be measured twice in the same lesion : One with the standard method and the other with the DWP method.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: FFR
Description: FFR will be measured twice in the same lesion : One with the standard method and the other with the DWP method.
Study: NCT04697849

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Rehabilitation and Exposure/Sorting Therapy
Description: Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) provides training in compensatory cognitive strategies to address the executive dysfunction typical of individuals with HD, then helps reduce the distress associated with discarding items via exposure therapy.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Case Management
Description: Case Management (CM). CM is the most widely available and utilized intervention for HD and is considered standard of care. This form of treatment involves managing the functional, housing, and legal ramifications of HD. Additionally, CM often involves assistance with economic, health, and social resources while providing support for the client.
Study: NCT06369688

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IDEAL SKIIN CARES bundles
Description: The investigators developed a specialized PIP care bundle, named IDEAL SKIIN CARES, through extensive review of literature and expert insights, which will be utilized for training WSNs and patients in the intervention group. This comprehensive bundle comprises 15 key components aimed at effectively preventing PIs: (1) Incontinence care status; (2) Dehydration status; (3) Elevate at-risk surfaces; (4) Attention to attached devices to skin; (5) Lotion use; (6) Skin assessment; (7) Keeping repositioning; (8) Individualized up-to-date knowledge; (9) Individualized medical devices selection; (10) Nutrition status; (11) Caregiver (formal and informal) participation; (12) Activity assessment; (13) Reducing friction/shear forces; (14) Evaluate hemodynamic instability; (15) and Scrutinizing comorbidities.
Study: NCT06147596

Intervention type: OTHER
Intervention: Head impact exposure
Description: The cohort is exposed to naturalistic head impacts (heading) during voluntary participation in a soccer match. All participants are regular soccer players and are therefore not exposed to excessive head impacts compared to their regular exposure.
Study: NCT05151341

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sample (20 ml)
Description: Blood sample will be tacken at inclusion, ONLY for case patients that agreed upon this. This sample will be addition to the collection for further research.
Study: NCT05950503

Intervention type: RADIATION
Intervention: Hepatic MRI
Description: The patients will undergo hepatic MRI in pre-established timepoints
Study: NCT06627725

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient-Family Communication
Description: Patient-Family Communication
Study: NCT06369688

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: IDEAL SKIIN CARES bundles
Description: The investigators developed a specialized PIP care bundle, named IDEAL SKIIN CARES, through extensive review of literature and expert insights, which will be utilized for training WSNs and patients in the intervention group. This comprehensive bundle comprises 15 key components aimed at effectively preventing PIs: (1) Incontinence care status; (2) Dehydration status; (3) Elevate at-risk surfaces; (4) Attention to attached devices to skin; (5) Lotion use; (6) Skin assessment; (7) Keeping repositioning; (8) Individualized up-to-date knowledge; (9) Individualized medical devices selection; (10) Nutrition status; (11) Caregiver (formal and informal) participation; (12) Activity assessment; (13) Reducing friction/shear forces; (14) Evaluate hemodynamic instability; (15) and Scrutinizing comorbidities.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IDEAL SKIIN CARES bundles workshop
Description: IDEAL SKIIN CARES bundles will be explained in detail by a trained research assistant in a workshop. This workshop is different from clinical training and following up about the IDEAL SKIIN CARES bundles.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Respiratory care workshop
Description: An unrelated topic, specifically respiratory care will be held in a workshop. This training will involve the distribution of educational pamphlets, brochures, and visual posters outlining key aspects of respiratory care
Study: NCT06017713

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: tDCS + symptoms provocation
Description: The treatment consists of 10 sessions of tDCS. Each tDCS session lasts 30 minutes at an intensity of 2mA and is preceded by a provocation of symptoms.
Study: NCT05764330

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietary Intervention
Description: Undergo CER intervention
Study: NCT05989165

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Minoxidil 5% Topical Solution
Description: Patient will be given minoxidil 5% topical solution, twice a day for 12 weeks
Study: NCT05515419

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic cord blood treatment
Description: Allogeneic cord blood treatment