TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06067698

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mesalamine and alpha-lipoic acid
Description: Mesalamine 1000 mg every 8 hrs. + alpha-lipoic acid 600 mg once daily for 3 months

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Mesalamine and Placebo
Description: Mesalamine 1000 mg every 8 hrs. + Placebo once daily for 3 months
Study: NCT03217617

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Direct intravenous injection of ivlv-X1 lentiviral vector
Description: ivlv-X1 LV intravenous injection at a dose of \~1x10e9/kg body weight.
Study: NCT01469507

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Chondroitin sulfate and sodium hyaluronate
Description: 3 weekly injections
Study: NCT05963126

Intervention type: OTHER
Intervention: No intervention.
Description: No intervention.
Study: NCT01469507

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronan
Description: 3 weekly injections
Study: NCT04956887

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AKL-T01
Description: The study intervention, AKL-T01 (Akili Interactive), is a digital, app-based intervention designed to target and improve cognition through an engaging video game-based software experience delivered on an iPad.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control Group
Description: Patients assigned to the control group will receive no intervention, as is typical for those with Covid-19 with respect to cognitive functioning
Study: NCT06363760

Intervention type: OTHER
Intervention: Safety and efficacy assessments
Description: Assessed throughout the duration of the study.
Study: NCT05586373

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: medication 1
Description: Ibuprofen pills, identical to the intervention (dipyrone pills), will be administered every 6 hour for a maximum of five days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: medication 2
Description: Dipyrone pills, identical to the intervention (ibuprofen pills), will be administered every 6 hour for a maximum of five days
Study: NCT06227286

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EECP
Description: EECP: 30-45 minutes/day, 5 days/week, 7 weeks, initiates with 0.030MPa.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham-EECP
Description: EECP: 30-45 minutes/day, 5 days/week, 7 weeks, constant to 75 mmHg.
Study: NCT06351787

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resting and movement-based focused awareness meditations
Description: Resting and movement-based focused awareness meditations

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resting and movement-based focused awareness meditations
Description: Resting and movement-based focused awareness meditations
Study: NCT06630104

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo hair and saliva sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Ancillary studies

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Follow-Up
Description: Undergo CFU

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Genetic Counseling
Description: Receive genetic counselor consultation
Study: NCT05606107

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tofacitinib
Description: Tofacitinib combined with other csDMARDs, but no glucocorticoids.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glucocorticoid
Description: Glucocorticoid
Study: NCT06232616

Intervention type: PROCEDURE
Group type: OTHER
Intervention: vitrectomy combined with intravitreal dexamethasone implant
Description: The dexamethasone implant will be injected into the vitreous cavity at the end of the surgery.
Study: NCT05534126

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Stellate Ganglion Block Treatment
Description: Stellate ganglion block procedure is a treatment that involves injection of local anesthetic around the stellate ganglion (located at the base of the neck) to block its transmission of pain signals.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sham
Study: NCT05146310

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: I.SPACE®
Description: I.SPACE® is a viscoelastic sodium hyaluronate gel use as a surgical aid in ophthalmic anterior segment surgery by maintaining the intraocular space and protecting the corneal endothelium.~The baseline injection is performed at V1. The volume of product to use will be at the Investigator discretion, and will be completely removed after surgery.
Study: NCT06464796

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Imagery Techniques
Description: * Play a video of person doing a toe-raise exercise where carrying a big barbell on his shoulders.~* The individual in the video proceeded from a neutral upright position to a tiptoe standing while loud a heavy barbell; the plantar-flexors are used in this workout.~* The members were said to imagine engaging their ankle flexor muscles in an effort to generate ankle flexion. Both limbs were used during the 10-second imaginary contraction, which was tailed by a 10-second rest. Subsequently five repetitions of the contraction, there was a 30 second pause. Two-minutes of rest were interspersed between five-sets of five-contractions. Fifty imaginary contractions in total.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Exercise Therapy
Description: 1. ROM drills for pronation, flexion and extension.~2. Ankle strengthening trainings include stand-up on tiptoe, walking on toe-tip, hopping on single foot, and resistance exercise with a latex elastic band.~3. Proprioceptive exercise include the following exercises: (a) sit on a proprioception board and move the injured limb in a round motion; (b) stand-up with both legs on the board while performing both eyes open and closed; (c) standing with single leg on the board while performing both eyes open; and (d) exercises on a mini-tramp (stand-up on double legs, single leg stances, hops on both left and right legs and on single leg).~4. Strengthening of the muscles of ankle completed with flexible bands at moderate Intensities.~5. Training on a stationary bicycle.~6. lunges forward into a wall.~7. Steps up and down on the transverse or sagittal plane.
Study: NCT06558409

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention:  Safer Still  Interactive Intervention
Description: An interactive intervention will be developed to help promote safe storage of firearms during the critical period immediately following high-risk care transitions.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Enhanced Usual Care (EUC):
Description: Families randomly assigned to the control condition will receive a psychological placebo that will feature an education only website developed by NCH's web design team. This website will cover warning signs for suicide, the leading methods of suicide - so that both conditions have content that features information about firearms - and locating professional help. The control website will NOT feature these three behavioral economic strategies--namely (a) multiple suggested alternatives for means restriction, (b) requests to justify inaction regarding means restriction, and (c) normative feedback about means restriction.
Study: NCT06201364

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: The external oblique intercostal block
Description: chest wall will be systematically scanned. Initially the probe will be placed in a cephalad to caudad paramedian direction at the anterior axillary line, and the external oblique muscle will be identified at the level ribs 6 and 7 in line with the xiphoid process to confirm correct identification of the external oblique muscle, the probe will be moved in the caudad direction following the external oblique muscle. At the subcostal level, the ultrasound probe will be rotated 90° to see the convergence with the internal oblique and transversus abdominus muscles. The probe will be then moved back to the initial identification point for the external oblique muscle. The EOI plane will be identified deep to the external oblique muscle and superficial to the sixth and seventh ribs and their associated intercostal muscles. Local anesthetic agent will be 20 ml volume (10 ml bupivacaine, 10 ml saline) will be injected under ultrasound guidance and this will be done bilaterally.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Paravertebral block
Description: involve injection of local anaesthetic in a space immediately lateral to where the spinal nerves emerge from the intervertebral foramina. This technique is being used increasingly for not only intra-operative and post-operative analgesia but also as a sole anaesthetic technique for carrying out various procedures.
Study: NCT04742959

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TT-00420
Description: TT-00420 tablet will be administered orally once daily per protocol defined schedule.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TT-00420
Description: TT-00420 tablet will be administered orally once daily per protocol defined schedule.
Study: NCT06244589

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic cholecystectomy
Description: Laparoscopic cholecystectomy: Cholecystectomy that performed with laparoscopic method

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic cholecystectomy
Description: Laparoscopic cholecystectomy: Cholecystectomy that performed with laparoscopic method

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Open-conversion cholecystectomy
Description: Open-conversion cholecystectomy: Cases in which laparotomy (Generally right subcostal incision) was performed based on intraoperative findings.
Study: NCT06460376

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wurn Technique
Description: Treatment:~Site-specific pressures for 30 seconds across the restrictive bands of adhered tissues and structures, working progressively deeper from the most superficial tissues Traction: focusing on these adhered areas, engage the uterine fundus and sidewalls and traction them to the left.~To assist and improve the mobility of the soft tissues, release the traction tension either suddenly or gradually, depending on the desired effect to decrease spasms and adhesions between the uterus and the bladder. The baseline treatment was moist heat.~Each therapy session was 30 minutes for 6 weeks and 2 sessions per week. 10 minutes for baseline treatment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mercier Therapy
Description: Treatment:~The patient lay face up on a massage or exam table. Feel viscera, major internal organs located in the abdomen by lightly pressing through abdominal muscles.~Manual poking, pressing, and massage actions do three things:~Reveals visceral adhesions. Find tender spots. Breaks up adhesions. Massaging and pressing stretch the collagen fibers that make up fascia, which loosens tightly bound fibers to break up adhesions. This releases the organs and allows them to move more freely.~Abdominal massage with pressing, deep strokes, and friction. The baseline treatment was moist heat. Each therapy session was 25 minutes for 6 weeks and 1 session per week. 10 minutes for baseline treatment
Study: NCT06272604

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized Exercise Rehabilitation
Description: The experimental group will participate in a 12-week exercise intervention program, carefully transitioning from moderate-intensity interval training to high-intensity interval training. The progression of exercise intensity will be regularly adjusted based on each child's tolerance, ensuring a personalized approach to the regimen. The exercise program is structured into three phases: an adaptation phase, an intensification phase, and a consolidation phase. For each participant, the intensity of the exercises is calculated based on their reserve heart rate, allowing for a tailored and scientifically-grounded progression. This approach aims to optimize the exercise program's effectiveness while maintaining safety and adaptability to individual fitness levels and asthma conditions.
Study: NCT04742959

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TT-00420
Description: TT-00420 tablet will be administered orally once daily per protocol defined schedule.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nab-Paclitaxel
Description: Nab-Paclitaxel would be administered via infusion on Day 1,8, and 15 of 28-day cycle
Study: NCT05251766

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: To analyze and compare the efficacy and safety of epirubicin + cyclophosphamide (EC) followed by docetaxel and EC followed by nab-paclitaxel in neoadjuvant chemotherapy of breast cancer; To analyze and compare the efficacy and safety of nab-paclitaxel combined with epirubicin + cyclophosphamide (EC) chemotherapy regimen in neoadjuvant therapy of breast cancer, so as to provide a new treatment option for patients with HER2-negative breast cancer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: To analyze and compare the efficacy and safety of epirubicin + cyclophosphamide (EC) followed by docetaxel and EC followed by nab-paclitaxel in neoadjuvant chemotherapy of breast cancer; To analyze and compare the efficacy and safety of nab-paclitaxel combined with epirubicin + cyclophosphamide (EC) chemotherapy regimen in neoadjuvant therapy of breast cancer, so as to provide a new treatment option for patients with HER2-negative breast cancer.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Docetaxel
Description: To analyze and compare the efficacy and safety of epirubicin + cyclophosphamide (EC) followed by docetaxel and EC followed by nab-paclitaxel in neoadjuvant chemotherapy of breast cancer; To analyze and compare the efficacy and safety of nab-paclitaxel combined with epirubicin + cyclophosphamide (EC) chemotherapy regimen in neoadjuvant therapy of breast cancer, so as to provide a new treatment option for patients with HER2-negative breast cancer.
Study: NCT04712383

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Fitbit Care intervention arm
Description: Entire suite of Fitbit Care.
Study: NCT05205525

Intervention type: OTHER
Intervention: Restrictive antibiotic strategy
Description: Implementation of a restrictive (delayed) antibiotic strategy in Ventilator Acquired Pneumonia suspicion without severity symptoms.

Intervention type: OTHER
Intervention: Aggressive antibiotic strategy
Description: Implementation of an aggressive (immediate) antibiotic strategy in Ventilator Acquired Pneumonia suspicion without severity symptoms.
Study: NCT05164796

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IVUS assessment of coronary ostia
Description: For coronary arteries at high-risk of obstruction during TAVI in native valves or valve-in-valve TAVI:~* IVUS analysis before valve implantation (+ coronary angiogram) to detect any leaflet interference with the coronary ostium, existing prior to the transcatheter heart valve (THV) placement~* IVUS analysis (+ coronary angiogram) after valve implantation in absence of acute coronary occlusion, to assess the patency of the ostium at-risk, the presence of native or degenerated surgical leaflet adjacent to the ostium, and the interaction of THV-frame with the coronary ostium.~* In case of CHIMNEY stenting, re-assessment of the stent expansion and coronary ostia patency with IVUS.
Study: NCT05469581

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A set of preventive interventions to improve adherence in vulnerable elderly people
Description: * reviewing the list of medications, delivery of an ordered list of medications, and checking medication regimen understanding;~* delivering a leaflet on the correct/safe taking of medications, discussion, explanation, and verification of understanding of the content;~* a counseling about the importance of adherence;~* handing over the medication dispenser (if the elderly person does not have one yet),~* delivering of a personal medication card, which shows the timeline of taking prescribed medication.
Study: NCT06341075

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)
Description: MRgLITT employs laser energy delivered through a stereotactically placed laser applicator to precisely ablate the epileptogenic tissue.
Study: NCT05239975

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SCTV01C
Description: intramuscular injection

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Comirnaty
Description: intramuscular injection
Study: NCT04819373

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BDB001
Description: BDB001 is an immunotherapy agent.
Study: NCT06227260

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
Description: Interventions among the 3 studies were categorized as other.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
Description: Interventions among the 3 studies were categorized as other.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
Description: Interventions among the 3 studies were categorized as other.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
Description: Interventions among the 3 studies were categorized as other.
Study: NCT06630104

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Genetic Testing
Description: Undergo sequencing analysis
Study: NCT06631911

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Emotional Awareness and Expression Therapy (EAET)
Description: Emotional Awareness and Expression Therapy (EAET) is a manualized, short-term psychodynamic therapy that, in this instance, is delivered in a group format.~The core of Emotional Awareness and Expression Therapy (EAET) involves helping individuals identify, understand, and express their emotions in a therapeutic setting. The therapy emphasizes the connection between unprocessed emotions and physical symptoms, encouraging participants to explore the emotional underpinnings of their distress. Through guided discussions, psychoeducation, and expressive exercises, participants learn to recognize patterns of emotional avoidance, develop self-compassion, and improve interpersonal communication. This process aims to reduce somatic symptoms and enhance overall emotional well-being by fostering a greater awareness of emotional experiences.
Study: NCT05246956

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intradialytic exercise
Description: Intradialytic exercise group
Study: NCT05372497

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention group (IG)
Description: Participants randomized to this treatment will receive a central nervous system-focused intervention consisting of a 20-session treatment program delivered in 30-45-minute sessions scheduled 5 days a week over a 4-week period and standard physical therapy will be continued.~* Chronic pain training will be given according to the needs of the person and 5-10 minutes will be allocated every day for the first week and chronic pain education will be divided into modules.~* Right / Left Discrimination Training~* Localization Training Level 1- Level 2 Training~* Visual imagination Training~* Visual Imagery Training~* Mirror Therapy~* Isometric and functional exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group (CG)
Description: The control group will receive only conventional physiotherapy. Conventional physiotherapy will be 5 days a week.~The conventional physiotherapy treatment session will take place as follows.~* Electrotherapy~* Scapular mobilization~* Passive stretches~* Stick Exercises~* Pendulum Exercises~* Shoulder flexion, extension, internal rotation, external rotation, horizontal abduction/ adduction strengthening exercises~Conventional physiotherapy intervention is planned for 45-60 minutes a day, five days a week for both groups.
Study: NCT05554289

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Depression Auxiliary Intervention Treatment Software
Description: Depression Auxiliary Intervention Treatment Software
Study: NCT05524233

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active Transcranial Direct Stimulation
Description: Subjects will receive a stimulation device to use up to 20 minutes daily for 4 weeks.
Study: NCT05390762

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Common phase
Description: A common face to face day hospital combining physical therapies with psychotherapeutic support such as Cognitive Behavioral Therapy to combat kinesiophobia.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Common phase
Description: A common face to face day hospital combining physical therapies with psychotherapeutic support such as Cognitive Behavioral Therapy to combat kinesiophobia.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telecare rehabilitation
Description: A Second phase of 5 weeks of telecare rehabilitation of the reconditioning type of 15 sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care in Face to Face
Description: A Second phase of 5 weeks of care in face to face day hospital of the reconditioning type of 15 sessions.
Study: NCT05375630

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin K2
Description: Vitamin K2
Study: NCT05872412

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin
Description: 60 mg/m2 IV bolus on day 1 every three weeks for four cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: 60 mg/m2 IV bolus on day 1 every three weeks for four cycles.
Study: NCT05554289

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Depression Auxiliary Intervention Treatment Software
Description: Depression Auxiliary Intervention Treatment Software