TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06544486

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caries Removal
Description: The cavity preparation and restoration were performed by a single operator. Infected dentin tissue was selectively removed. The differentiation between infected and affected dentin was determined by the clinician through the visual-tactile method.Isolation was achieved with cotton rolls and suction.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caries Removal
Description: The cavity preparation and restoration were performed by a single operator. Infected dentin tissue was selectively removed. The differentiation between infected and affected dentin was determined by the clinician through the visual-tactile method.Isolation was achieved with cotton rolls and suction.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caries Removal
Description: The cavity preparation and restoration were performed by a single operator. Infected dentin tissue was selectively removed. The differentiation between infected and affected dentin was determined by the clinician through the visual-tactile method.Isolation was achieved with cotton rolls and suction.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caries Removal
Description: The cavity preparation and restoration were performed by a single operator. Infected dentin tissue was selectively removed. The differentiation between infected and affected dentin was determined by the clinician through the visual-tactile method.Isolation was achieved with cotton rolls and suction.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Filling
Description: Sectional matrix systems and interdental wedges were used to achieve an anatomical contour and contact. Then, the selected materials were placed in the cavity according to the manufacturers' recommendations.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Filling
Description: Sectional matrix systems and interdental wedges were used to achieve an anatomical contour and contact. Then, the selected materials were placed in the cavity according to the manufacturers' recommendations.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Filling
Description: Sectional matrix systems and interdental wedges were used to achieve an anatomical contour and contact. Then, the selected materials were placed in the cavity according to the manufacturers' recommendations.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Filling
Description: Sectional matrix systems and interdental wedges were used to achieve an anatomical contour and contact. Then, the selected materials were placed in the cavity according to the manufacturers' recommendations.
Study: NCT06536712

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stem Cells Derived Exosomes
Description: Mesenchymal Stem Cells Derived Exosomes will be administered intraperitoneally to patients at the end of their surgery

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 10 patients will receive intraperitoneal placebo at the end of their surgery
Study: NCT05292170

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heat acclimation
Description: 10 consecutive days of heat acclimation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heat acclimation
Description: 10 consecutive days of heat acclimation
Study: NCT06263309

Intervention type: DIAGNOSTIC_TEST
Intervention: Femoral neck shortening measurement
Description: We examine femoral neck shortening in patients with femoral neck fractures.

Intervention type: DIAGNOSTIC_TEST
Intervention: Femoral neck shortening measurement
Description: We examine femoral neck shortening in patients with femoral neck fractures.
Study: NCT04543045

Intervention type: OTHER
Intervention: not an intervention
Description: not an intervention

Intervention type: OTHER
Intervention: not an intervention
Description: not an intervention
Study: NCT05200702

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Knee-hip Powered Soft Exoskeleton (MyoSuit, MyoSwiss, Zurich, Switzerland)
Description: Patients and healthy subjects will wear the movement assistance device to perform different standardised physical evaluations.
Study: NCT05774509

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Extracellular vesicle-enriched secretome of cardiovascular progenitor cells differentiated from induced pluripotent stem cells
Description: Repeated (X3) intravenous infusions of the extracellular vesicle-enriched secretome of cardiovascular progenitor cells (differentiated from human induced pluripotent stem cells)
Study: NCT05124756

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bioelectric stimulation
Description: The sessions will include 20 minutes for stimulation of the thigh muscles and 45 minutes for stimulation of the kidneys. The electrodes will be placed on the motor point of the quadriceps muscle in both lower limbs. The neuromuscular electric stimulation will be applied by symmetrical biphasic pulsed current, at an 80 Hz frequency, 400 ms pulse width, 10 s contraction time, rest time decreasing as the protocol advanced, at reciprocal mode. The intensity will be individually adjusted to produce visible muscle contraction. Concomitant, two electrodes will be placed in the abdominal corresponding to the kidney anatomical site and two electrodes on the dorsal region at the level of the 10th thoracic vertebra. The stimulation of the kidneys will include in addition to Klotho, precise signals for several pro-regenerative proteins. The intensity of the electric current will be individually adjusted to sensory stimulation.
Study: NCT04813900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lung ultrasound
Description: Lung ultrasound in order to calculate lung ultrasound score
Study: NCT06503341

Intervention type: OTHER
Intervention: Cardiovascular risk assesment
Description: ASCVD Score and WHO Cardiovascular Risk score.
Study: NCT06479694

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Real-life Dual-Task Training
Description: The intervention is Real-life Dual-Task Training (Real-DTT) which uses instrumental activities of daily living training with explicit focus on the cognitive and motor elements and when to focus attention to one vs. the other to reduce fall risk. The Real-DTT sessions will be delivered once a week for 10 weeks during their occupational therapy sessions, delivered by a licensed occupational therapist. Real-DTT is a modified version of occupational therapy, with a protocol tailored to the participants.
Study: NCT06701526

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eptinezumab
Description: Solution for infusion
Study: NCT05192226

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counterfactual Strategy
Description: Participants in this intervention condition will think about their past and identify how a less than desirable physical activity event could have turned out better using counterfactual thinking (i.e., If only I... then....). After identifying actions they could have taken to reach a better outcome in their physical activity event, they will then apply those thoughts to the future upcoming week so they can be realized.
Study: NCT04833842

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Web-based childbirth preparation program developed based on health belief model and supported by motivational interview
Description: In the three-month study, primigravida women in the initiative group will be given a web-based childbirth preparation program, which is prepared based on the Health Belief Model and supported by motivational interviews. Before starting the training program, pre-test will be applied to pregnant women and a five-week program will be implemented. A final test will be applied at the end of the program. The birth process will be evaluated immediately after the pregnant women give birth.
Study: NCT06683612

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PIPE-791
Description: Subjects will receive a single oral dose of PIPE-791.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PIPE-791
Description: Subjects will receive a single oral dose of PIPE-791.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PIPE-791
Description: Subjects will receive a single oral dose of PIPE-791.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PIPE-791
Description: Subjects will receive a single oral dose of PIPE-791.
Study: NCT06700538

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-INHBE
Description: SC injection
Study: NCT05084690

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Unilateral resistance training
Description: Unilateral resistance training of the elbow flexors
Study: NCT06700538

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARO-INHBE
Description: SC injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: calculated volume to match active treatment by SC injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: calculated volume to match active treatment by SC injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: SC injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tirzepatide
Description: SC injection
Study: NCT06698770

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Anticipated long-term use of medication
Description: In this hypothetical scenario, the doctor anticipates that the participant will take this medication for the rest of their life.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Anticipated long-term use of medication
Description: In this hypothetical scenario, the doctor anticipates that the participant will take this medication for the rest of their life.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Anticipated long-term use of medication
Description: In this hypothetical scenario, the doctor anticipates that the participant will take this medication for the rest of their life.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Anticipated long-term use of medication
Description: In this hypothetical scenario, the doctor anticipates that the participant will take this medication for the rest of their life.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Period re-evaluation of medication
Description: In this hypothetical scenario, the doctor anticipates that the participant will take this medication for the rest of their life but will periodically re-evaluate the benefits and risks of the medication.
Study: NCT05084690

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unilateral resistance training
Description: Unilateral resistance training of the elbow flexors

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Illusionary mirror visual feedback
Description: Modified Ramachandran's mirror box
Study: NCT06461923

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Insole wearing
Description: The insole-wearing group is instructed to wear the insole gait analysis device as frequently and for as long as possible during outdoor activities. Participants receive feedback during 3rd to 4th week via telephone. Following a period of 6 weeks, an evaluation of the usability and satisfaction of the insole gait analysis device will be conducted.
Study: NCT05266781

Intervention type: PROCEDURE
Intervention: Surgical repair
Description: Patients affected by a thoracoabdominal aortic aneurysm who received an open surgical repair (aneurysmectomy and aortic reconstruction with a surgical graft

Intervention type: PROCEDURE
Intervention: Endovascular repair
Description: Patients affected by a thoracoabdominal aortic aneurysm who received endovascular repair (with off-the-shelf or custom-made Fenestrated/Branched-Endovascular Aortic Repair - F/BEVAR)
Study: NCT05975021

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Istaroxime
Description: IV infusion via a syringe pump. Dosage of 1.0 µg/kg/min for 6 hours; 1.0 or 0.5 µg/kg/min for 18 hours, 0.5 µg/kg/min for 24 hours. Total duration 48 hours.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: IV infusion via a syringe pump. Total duration 48 hours.
Study: NCT03266549

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: botulinum toxin augmented surgery
Description: unilateral recess-resect procedure, or bilateral rectus muscle recession plus intraoperative injection of 2.5 to 5 units of botulinum toxin A into the recessed muscle.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional surgery
Description: unilateral recess-resect procedure, bilateral rectus muscle recession, or 3 horizontal rectus muscle surgery according to the type of strabismus and the presence or absence of deep amblyopia. The standard correction tables will be used as a guide for the amount of muscle recession and, or resection.
Study: NCT05565183

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MRI (with injection of contrast product)
Description: All patients included in the study will undergo two MRI examinations (with injection of contrast product) before and after the ablation procedure.
Study: NCT05791942

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reminder of preventive care measures
Description: The investigators will send randomized participants an SMS reminder encouraging them to click the provided link and close their outstanding, overdue preventive care measures.~The provided link will take them to their MyChart login page; after logging in, they would see their personalized My Action Plan Letter detailing their personalized, overdue preventive care measures.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reminder of preventive care measures
Description: The investigators will send randomized participants an SMS reminder encouraging them to click the provided link and close their outstanding, overdue preventive care measures.~The provided link will take them to their MyChart login page; after logging in, they would see their personalized My Action Plan Letter detailing their personalized, overdue preventive care measures.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reminder of preventive care measures
Description: The investigators will send randomized participants an SMS reminder encouraging them to click the provided link and close their outstanding, overdue preventive care measures.~The provided link will take them to their MyChart login page; after logging in, they would see their personalized My Action Plan Letter detailing their personalized, overdue preventive care measures.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Persuasion via anecdote
Description: The message will contain an anecdote of a patient whose cancer was caught early through similar, recommended preventive screenings.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral: Action prompt
Description: The message will prompt people to take care of the health gap right away before it slips their mind.
Study: NCT06698770

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Period re-evaluation of medication
Description: In this hypothetical scenario, the doctor anticipates that the participant will take this medication for the rest of their life but will periodically re-evaluate the benefits and risks of the medication.
Study: NCT05995145

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active hamstring flexibility exercises with hip flexion mobilization
Description: 8 weeks x 5 times per week for 20 min. In the experimental intervention, the exercise program will be based on participant education, home-based individual exercises, and regular group meetings for check-ups by a physiotherapist according to a precise set schedule.
Study: NCT04833842

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Web-based childbirth preparation program based on health belief model
Description: In the three-month study, a web-based childbirth preparation program based on the Health Belief Model will be applied to primigravida women in the control group. Before starting the training program, pre-test will be applied to pregnant women and a five-week program will be implemented. A final test will be applied at the end of the program. The birth process will be evaluated immediately after the pregnant women give birth.
Study: NCT06186973

Intervention type: OTHER
Intervention: Monitoring with Neobeat heart rate meter
Description: At the designated time for cord clamping as per clinical indication, a 10 cm segment of the umbilical cord will be double-clamped and 5 ml of preferably arterial blood will be obtained.~In infants brought to the resuscitation table, six ECG electrodes will be placed on the skin and cardiac output will be measured with a hemodynamic monitor (PhysioFlow®) for at least 10 min, or until the end of resuscitation/stabilization.

Intervention type: OTHER
Intervention: Monitoring with Neobeat heart rate meter
Description: At the designated time for cord clamping as per clinical indication, a 10 cm segment of the umbilical cord will be double-clamped and 5 ml of preferably arterial blood will be obtained.~In infants brought to the resuscitation table, six ECG electrodes will be placed on the skin and cardiac output will be measured with a hemodynamic monitor (PhysioFlow®) for at least 10 min, or until the end of resuscitation/stabilization.

Intervention type: OTHER
Intervention: Maternal arterial blood gases
Description: Arterial blood gases will be drawn from a radial artery line and analyzed at the end of a contraction at pre-specified time points during labor.

Intervention type: OTHER
Intervention: Maternal arterial blood gases
Description: Arterial blood gases will be drawn from a radial artery line and analyzed at the end of a contraction at pre-specified time points during labor.

Intervention type: OTHER
Intervention: Amniotic fluid lactate
Description: Amniotic fluid will be collected (2mL) and analyzed at pre-specified time points after rupture of the membranes.

Intervention type: OTHER
Intervention: Amniotic fluid lactate
Description: Amniotic fluid will be collected (2mL) and analyzed at pre-specified time points after rupture of the membranes.
Study: NCT04697511

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Participants will receive single oral dose of midazolam on Days 1, 3 and 13 under fed conditions.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: M2951
Description: Participants will receive multiple oral doses (twice daily) of M2951 on Day 3 to Day 13 under fed conditions.
Study: NCT05818501

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The dysphagia cups
Description: After the training period of the one of dysphagia cups, participants will start using cup to consume water during a designated period of time every day.~Participants consuming water with Cup A will drink from a static position with their chins towards their chests, the so-called Chin-Tuck maneuver. This position leads epiglottal naturally covering the trachea and causes liquid only ﬂowing to the esophagus and thus stomach. The restoring force of the membrane ensures a constant level of liquid at the upper edge of the cup and thus enables this preferred and safe drinking position.~Cup B limits the maximum volume of water flowing out of the Cup B designated by the staff. Controlled liquid flow prevents overflowing the mouth and gulping, thus reduces the risk of choking and liquid aspiration. Participants can choose to drink the water from Cup B with a straw when necessary.
Study: NCT05470699

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo PET/CT

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fluorine F 18 Piflufolastat
Description: Given IV

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT
Study: NCT04276480

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Piperacillin-tazobactam
Description: At the time of ventilator-associated pneumonia diagnosis, patients will receive an initial 4g loading dose of piperacillin-tazobactam with a continuous maintenance dose of 16g per day the first day of treatment. The dose of the piperacillin-tazobactam administered the following days will be adjusted to the renal function.~The antimicrobial treatment will be adjusted to the narrower-spectrum agent after the antimicrobial susceptibility determination for a total length of treatment of seven days.
Study: NCT05002790

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Data collection group
Description: Magnetic resonance imaging (MRI) allows measurement of the axes described to suggest which head and neck position would provide best anatomical alignment to reduce anterior impingement.~All the MRI scans will be conducted using 3.0 Tesla (Optima 750w, GE Medical, Milwaukee, WI, USA) using the cervical spine section of the coil. T2-weighted images in the sagittal plane will be acquired using a fast recovery fast spin echo (FRFSE) technique. The scans will take around two and half minutes and a member of the anaesthetic investigator team will be present to facilitate positional changes and maintain consistency. MRI scanning will be performed in following 3 head and neck positions:~Neutral position, Sniffing position and the Extension position.
Study: NCT05906381

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics
Description: A specific probiotics capsule product, containing Streptococcus thermophilus will be given to participants for oral intake for 35 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A specific capsule product, containing microcrystalline cellulose will be given to participants for oral intake for 35 days.
Study: NCT05820529

Intervention type: PROCEDURE
Group type: OTHER
Intervention: adenotonsillectomy
Description: removal of adenoid,tonsil in one session
Study: NCT04132232

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels
Description: Will use the Smokerlyzer® device at each visit and be provided information on exhaled carbon monoxide and fetal carboxyhemoglobin. Risks of adverse perinatal outcomes related to maternal carbon monoxide and fetal carboxyhemoglobin level will be provided.