TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06264570

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: B-TMG supplementation
Description: B-TMG supplement (B2 riboflavin, B6 pyroxidine, B9 methylfolate, B12 methylcobalamine, S-adenosylmethionine, Trimethylglycerol (TMG), zinc sulfate) for subjects with normal COMT gene and MTHFR gene polymorphism

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: B-SAM supplementation
Description: B-SAM supplement (B2 riboflavin, B6 pyroxidine, B9 folic acid, B12 adenosylcobalamin, magnesium, S-adenosylmethionine) for Subjects with COMT gene polymorphism or normal COMT gene and normal MTHFR gene

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: B-TMG placebo
Description: B-TMG placebo for subjects with normal COMT gene and MTHFR gene polymorphism

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: B-SAM placebo
Description: B-SAM placebo for Subjects with COMT gene polymorphism or normal COMT gene and normal MTHFR gene
Study: NCT05677490

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Given IV
Study: NCT01868048

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sativex
Description: Contains delta -9 tetrahydrocannabinol (THC), 27 mg/mL:cannabidiol (CBD), 25 mg/mL, in ethanol:propylene glycol (50:50) excipients, with peppermint oil (0.05%) flavoring.~Subjects receive study medication delivered in 100 microlitre actuations by a pump action oromucosal spray. Maximum permitted dose is 10 actuations per day. Each actuation delivers THC 2.7 mg and CBD 2.5 mg.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oromucosal spray, containing no active drug but ethanol:propylene glycol (50:50) excipients, with peppermint oil (0.05%) flavoring and colorants. Maximum permitted dose is 10 actuations per day.
Study: NCT05547178

Intervention type: OTHER
Intervention: Qualitative interview - eurythmy group
Description: Participants will be interviewed about self-perceived changes in everyday life during participation in the eurythmy intervention of the ENTAiER study.

Intervention type: OTHER
Intervention: Qualitative interview - tai chi group
Description: Participants will be interviewed about self-perceived changes in everyday life during participation in the tai chi intervention of the ENTAiER study.

Intervention type: OTHER
Intervention: Qualitative interview - standard care group
Description: Participants will be interviewed about self-perceived changes in everyday life during participation in the standard care group of the ENTAiER study.
Study: NCT05268926

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin 10Mg Tab
Description: dapagliflozin 10 mg/d or matched placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05972460

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMM2510
Description: IMM2510 is administered intravenously every 2 weeks, every 28 days for a treatment cycle.
Study: NCT06428578

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FBM-In person
Description: Participants will receive two home visits by a CHW. Each home visit will last about 30 minutes, during which the CHW will assist the woman with community resources and help with enrolling in any state or federal nutrition and medical programs. Furthermore, the participants will be given access to a private Facebook group for nutrition, health education, and social support. Home visits will occur during the second and fifth weeks of the study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FBM-Virtual
Description: Participants will receive access to a virtual platform which will have information on national, state, and local food and medical resources, as well as local community resources, and will have access to a private Facebook group for nutrition, health education, and social support.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: home delivered food boxes
Description: Participants will receive weekly deliveries of a box containing fresh produce and staple goods (approximately 5 meals a week), culturally tailored meals (6 meals a week), and prepared fruit, vegetable and grain-forward meal kits (4 units a week) plus standard nutrition education materials consisting of recipes inside of the boxes. Each participant will receive one box for eight consecutive weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: home delivered food boxes
Description: Participants will receive weekly deliveries of a box containing fresh produce and staple goods (approximately 5 meals a week), culturally tailored meals (6 meals a week), and prepared fruit, vegetable and grain-forward meal kits (4 units a week) plus standard nutrition education materials consisting of recipes inside of the boxes. Each participant will receive one box for eight consecutive weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: home delivered food boxes
Description: Participants will receive weekly deliveries of a box containing fresh produce and staple goods (approximately 5 meals a week), culturally tailored meals (6 meals a week), and prepared fruit, vegetable and grain-forward meal kits (4 units a week) plus standard nutrition education materials consisting of recipes inside of the boxes. Each participant will receive one box for eight consecutive weeks.
Study: NCT05725356

Intervention type: OTHER
Group type: OTHER
Intervention: Basic body awareness therapy
Description: Participants were instructed to focus on maintaining good posture, balance, uninterrupted breathing, increased awareness, and decreasing unnecessary muscle tension.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Basic body awareness therapy
Description: Participants were instructed to focus on maintaining good posture, balance, uninterrupted breathing, increased awareness, and decreasing unnecessary muscle tension.
Study: NCT05182554

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Doctor Videos
Description: Receive ads on Facebook or through our website with videos in which health professionals tell people to get the Covid-19 vaccine. The health professionals answer common questions about the Covid-19 vaccine, such as how mRNA vaccines work, and what types of side effects to expect.
Study: NCT05677490

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluorouracil
Description: Given IV
Study: NCT05243264

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empower@Home
Description: The intervention is a 10-week course of internet-based cognitive behavioral therapy. During the active intervention phase, participants will receive a weekly check-in call to see how they are doing. The weekly check-in call is intended to be brief and last no more than 10 minutes on average.
Study: NCT05625828

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-motor Physical Activity
Description: Physical activity program that consist of 1 sessions per week during 10 weeks (from Week 2 to Week 11). Each session includes a 10 minutes warm up with light walking, 45 minutes of cognitive-motor exercises where participants have to perform two tasks consequently (for example, walking while answering math questions or throwing a ball while reverse walking) and 5 minutes of stretching exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Multifactorial Physical Activity
Description: Physical activity program that consist of 1 sessions per week during 10 weeks (from Week 2 to Week 11). Each session includes a 10 minutes warm up with light walking, 45 minutes of multifactorial exercises that consists of high speed walking, resistance training and balance training in single task condition and 5 minutes of stretching exercises.
Study: NCT05677490

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin Calcium
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leucovorin Calcium
Description: Given IV
Study: NCT06336252

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital nudging intervention target to change behavior
Description: In hospital Participants in the intervention group will receive usual hospital care and be provided with a sensor collecting data on physical activity level during hospitalisation AND a monitor placed at their bedside that displays information about their physical activity level, in terms of time spent bedridden, sitting, standing, and walking. This information will be visible to the health personnel, the patients, and their relatives. This feedback system is developed and provided by SENS Innovation.~After discharge The visual feedback system from SENS will be continued after discharge and include an E-sport biking system provided by 4Mvideo. This integrated new system will combine an ergometer bike or sofa bike installed in the patient's own home or nursing home, and data from the sensor that the participants continue to wear after discharge will go into the SENS system, feeding back a visual track of their activities
Study: NCT06548984

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: diaphragmatic exercises
Description: Perform controlled and supervised diaphragmatic exercises

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Respiratory muscle training
Description: Perform respiratory muscle training with controlled and supervised devices
Study: NCT05677490

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Nivolumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study: NCT05522439

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1703
Description: SHR-1703 will be administered by SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1703
Description: SHR-1703 will be administered by SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1703
Description: SHR-1703 will be administered by SC injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SHR-1703 Placebo
Description: Matching Placebo will be administered by the SC route.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1703 Placebo
Description: Matching Placebo will be administered by the SC route.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1703 Placebo
Description: Matching Placebo will be administered by the SC route.
Study: NCT05654129

Intervention type: OTHER
Group type: OTHER
Intervention: saliva samples
Description: saliva samples (non-invasive, in the sites evaluated during the partial survey) will be perform by one of the investigators .

Intervention type: OTHER
Group type: OTHER
Intervention: saliva samples
Description: saliva samples (non-invasive, in the sites evaluated during the partial survey) will be perform by one of the investigators .

Intervention type: OTHER
Group type: OTHER
Intervention: medical questionnaire
Description: a complete medical questionnaire will be carried out (general, lifestyle and quality of life) will be perform by one of the investigators .

Intervention type: OTHER
Group type: OTHER
Intervention: medical questionnaire
Description: a complete medical questionnaire will be carried out (general, lifestyle and quality of life) will be perform by one of the investigators .
Study: NCT04476238

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Inosine
Description: 2 grams of inosine dissolved in 250 ml water taken by mouth

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 250 ml water taken by mouth
Study: NCT05697458

Intervention type: OTHER
Intervention: computerized tomography scanning
Description: In all patients the investigators will perform CT for determination of iliac arteries calcifications
Study: NCT05039359

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FlecIH-103
Description: flecainide acetate inhalation solution

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: FlecIH-103
Description: flecainide acetate inhalation solution
Study: NCT05056532

Intervention type: DIAGNOSTIC_TEST
Intervention: patient assessment
Description: subjective and objective measurement will be performed in patients with PAH

Intervention type: DIAGNOSTIC_TEST
Intervention: patient assessment
Description: subjective and objective measurement will be performed in patients with PAH
Study: NCT05656209

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus acidophilus
Description: Lactobacillus acidophilus solid drink (pure bacteria, food grade, JYLA-191, Shandong Zhongke Jia-yi Biological Engineering Co., LTD.), 3G (containing 2\*10\^10CFU), twice a day, once in the morning and once in the evening, 1 bag each time, by drinking water, direct oral intake, 1 month/course, continuous use for three courses.
Study: NCT05061173

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise training Group
Description: Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 30 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 30 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 30 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Exercise Training Group
Description: Resistive Exercises includes (a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction.~At Week 1-2, 10 repetitions 1 set, 3 days/week, for 30 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 30 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 30 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined Exercise Training Group
Description: Combined Exercise training includes \[Aerobic: Treadmill walking + Resistive Training: a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction\] Time will be reduced to 15 minutes for both trainings in respective weeks. Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 15 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 15 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 15 minutes~Resistive Exercises At Week 1-2, 10 repetitions 1 set, 3 days/week, for 15 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 15 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 15 minutes
Study: NCT06197828

Intervention type: OTHER
Intervention: This study is an observational studie which have no intervention
Description: This study is an observational studie which have no intervention

Intervention type: OTHER
Intervention: This study is an observational studie which have no intervention
Description: This study is an observational studie which have no intervention
Study: NCT06425003

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] ABBV-CLS-7262
Description: Oral Solution
Study: NCT06457386

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: systematic echocardiography
Description: transthoracic echocardiography (TTE) will be performed as soon as possible within 14 days following the first blood sample collection for SAB diagnosis, completed, if required, by a transoesophageal (TEE) echocardiography based on the judgment of the echocardiographist.~SAB in patients of both arms will be treated according to current recommendations, taking into account the result of the echocardiography in the control arm.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: no echocardiography arm
Description: no echocardiography will be performed unless occurrence of new events evocating IE (extra-cardiac events or positive Staphylococcus aureus blood culture), based on the clinical judgment of the investigator.~SAB in patients of both arms will be treated according to current recommendations, taking into account the result of the echocardiography in the control arm.
Study: NCT04656873

Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo collection of cheek swab, blood, urine, stool, and tissue samples for research

Intervention type: OTHER
Intervention: Medical Chart Review
Description: Periodic review of medical records for clinical parameters (labs, ICI dosing and frequency, occurrence, timing and type of irAE, irAE management, etc.) along with relevant demographic information (age, sex/gender, race/ethnicity, insurance type, etc.).

Intervention type: OTHER
Intervention: Questionnaires/Surveys
Description: Periodic self-report questionnaires/surveys for symptom tracking, quality of life, perinatal outcomes, etc.
Study: NCT05230186

Intervention type: PROCEDURE
Intervention: Tumor Biopsy
Description: Research biopsy of solid tumor or sharing of excess tumor tissue during a planned surgical or biopsy procedure and a companion blood sample.

Intervention type: PROCEDURE
Intervention: Tumor Biopsy
Description: Research biopsy of solid tumor or sharing of excess tumor tissue during a planned surgical or biopsy procedure and a companion blood sample.

Intervention type: PROCEDURE
Intervention: Tumor Biopsy
Description: Research biopsy of solid tumor or sharing of excess tumor tissue during a planned surgical or biopsy procedure and a companion blood sample.
Study: NCT05118256

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirfenidone Oral Tablet
Description: Patients will be treated with pirfenidone (oral tablets) during 6 months
Study: NCT06045338

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mind Body Intervention #1
Description: The mind-body intervention will include regular 1 to 2 hour educational sessions and lectures, as well as supplemental reading material. In addition, individualized sessions will be offered each week for students who have additional questions and/or need additional time with the material.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mind Body Intervention #1
Description: The mind-body intervention will include regular 1 to 2 hour educational sessions and lectures, as well as supplemental reading material. In addition, individualized sessions will be offered each week for students who have additional questions and/or need additional time with the material.
Study: NCT06548204

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fexofenadine Hydrochloride 60mg bid
Description: Fexofenadine hydrochloride 60mg bid treatment for 6 months.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administration for 6 months.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fexofenadine Hydrochloride 120mg bid
Description: Fexofenadine hydrochloride 120mg bid treatment for 6 months.
Study: NCT04858945

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Teach-back method
Description: During the trial, women from teach-back group and controlled group will receive three education sessions The topics discussed at the first session included delivery mode, labor process and pain relief, newborn health and care (common health issues and care skills), perinatal die and excises, and perinatal psychological health. The topics discussed at the second session includ postpartum recovery, postpartum maternal health, perineum care (diet, oral care, perineal care, and hygiene), breastfeeding, postpartum blue and depression, neonatal care, neonatal screening tests, newborn vaccination and early child development. At two-week postpartum, the educator answers questions raised by the woman and gives advices on the challenges and difficulties in postpartum recover and caring newborn faced by the woman.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Teach-back method
Description: During the trial, women from teach-back group and controlled group will receive three education sessions The topics discussed at the first session included delivery mode, labor process and pain relief, newborn health and care (common health issues and care skills), perinatal die and excises, and perinatal psychological health. The topics discussed at the second session includ postpartum recovery, postpartum maternal health, perineum care (diet, oral care, perineal care, and hygiene), breastfeeding, postpartum blue and depression, neonatal care, neonatal screening tests, newborn vaccination and early child development. At two-week postpartum, the educator answers questions raised by the woman and gives advices on the challenges and difficulties in postpartum recover and caring newborn faced by the woman.
Study: NCT05067842

Intervention type: DIAGNOSTIC_TEST
Intervention: Circulating tumor DNA(ctDNA) level measurement
Description: The ctDNA level will be measured using the Signatera platform developed by Natera, Inc. Signatera is a patient-specific, tumor informed custom-built ctDNA monitoring assay.
Study: NCT04690400

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental: Active care group
Description: Stretching exercise program remotely supervised. Total of approximately 40 minutes per session by WhatsApp, individually and supervised by a professional (physiotherapist or physical education teacher). As recommended for flexibility improving, 30 seconds of stretching in each exercise will be perform fractionated (3 series of 10 seconds of static position at the point of moderate discomfort, with 10 seconds interval between series). There will be two stretching protocol models with exercises variations, but for the same muscle groups, intensity, volume, and duration. The position at the point of moderate discomfort will be self-adjusted by subjective perception over 12 weeks of intervention. The protocol model will change after seven weeks. In order to make the interventions more similar, the guide and videos of control group will be also sent to experimental group

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator: Self-care group
Description: The participants will receive counseling to stretching by guide and explanatory video that will be send by WhatsApp. The stretching exercise protocols will be the same performed by the experimental group. In addition, participants will receive recommendation to perform the protocol with the same weekly frequency, intensity, volume, and duration perform by the experimental group After the guide and explanatory video are sent, participants will receive a call for clarification. As well as in the experimental group, the protocol model will change after seven weeks; so, other guide and explanatory video will be sent for participants.
Study: NCT04821427

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief mhealth intervention + mobile messaging to reduce sexual risk behavior and heavy drinking
Description: The intervention is a brief, motivational video-conferencing intervention followed by four weeks of app-based, interactive mobile messages to reduce heavy episodic drinking and sexual risk behavior (condomless anal intercourse) among Black/African American and Hispanic/Latino men who have sex with men