TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06191497

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: non surgical periodontal therapy
Description: NSPT based on Guided biofilm therapy principle (EMS Dental, Switzerland)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: non surgical periodontal therapy
Description: NSPT based on Guided biofilm therapy principle (EMS Dental, Switzerland)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: non surgical periodontal therapy
Description: NSPT based on Guided biofilm therapy principle (EMS Dental, Switzerland)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: non surgical periodontal therapy
Description: NSPT based on Guided biofilm therapy principle (EMS Dental, Switzerland)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chlorhexidine mouthwash
Description: 0.12% chlorhexidine based mouthwash used twice a day for 15 days after therapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chlorhexidine mouthwash
Description: 0.12% chlorhexidine based mouthwash used twice a day for 15 days after therapy
Study: NCT05358028

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hand Arm Bimanual Intensive Technique including Lower Extremity (HABIT-IL)
Description: HABIT-ILE along with the conventional Bobath treatment will be performed for 30 days in the form of groups for 3 hours, children will be performing individual activities.~Functional task as maintaining ADL:~i.Eating with spoon while standing ii. Combing hair while standing. iii. Counting cards while standing and putting them in box. Standing and walking I. standing with support of upper extremity II. walking with the help walkers III. walking on parallel bar playing activities: I. playing with cards while standings II. taking toys out of box and putting them in other box while standing III. grasping a fixed rod by hand and trying to maintain balance on physio stability ball

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hand Arm bimanual intensive Technique (HABIT)
Description: HAIBT along with the conventional Bobath treatment will be performed for 30 days in the form of groups for 3 hours, children will be performing individual activities HAIBT along with the conventional Bobth treatment will be performed for 30 days in the form of groups for 3 hours, children will be performing individual activities~Playing activities on table:~I. building towers with Lego blocks, II. Holding book by one hand and turning pages , III. Playing games with cards, IV. Drawing random impressions on paper, V. taking toys out of one box and placing them in other box one by one~Activities of daily living :~I. eating with spoon from bowel II. combing hair while sitting, III. opening of bottle cap for drinking water Age appropriate video games while sitting will be provided according to the ease of children
Study: NCT04054752

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant human IL-7-hyFc (NT-I7)
Description: NT-I7 administered at escalating doses of 720, and 960g/kg to determine OBD of NT-I7

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaccine sequence 1
Description: Day 1 Immunization Pre-NT-I7:Td and Polio Day 64, Immunization Post-NT-I7: Hep A#1, Hep B#1 Day 106: Hep B#2 (Optional) 6 Month Post NT-I7 Vaccines (Optional): Polio, Hep A#2, Hep #3, PPSV23#1

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaccine sequence 2
Description: Day 1 Immunization Pre-NT-I7: Hep A#1, Hep B#1 Day 64, Immunization Post-NT-I7:Td and Polio Day 106: no Vaccine 6 Month Post NT-I7 Vaccines (Optional): Polio, Hep A#2, Hep #3, PPSV23#1
Study: NCT06046768

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychological care
Description: Psychological consultations (interviews, scales), participation in a discussion group for parents in Visio via Zoom, a speech therapy assessment and possible complementary multidisciplinary consultations)
Study: NCT05709015

Intervention type: OTHER
Group type: OTHER
Intervention: Neutral electrolyzed water
Description: Use of mouthwash containing neutral electrolyzed water twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: OTHER
Group type: OTHER
Intervention: Neutral electrolyzed water
Description: Use of mouthwash containing neutral electrolyzed water twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: OTHER
Group type: OTHER
Intervention: Neutral electrolyzed water
Description: Use of mouthwash containing neutral electrolyzed water twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: Use of mouthwash containing placebo twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: Use of mouthwash containing placebo twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: Use of mouthwash containing placebo twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: DRUG
Group type: OTHER
Intervention: Chlorhexidine digluconate
Description: Use of mouthwash containing chlorhexidine digluconate twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: DRUG
Group type: OTHER
Intervention: Chlorhexidine digluconate
Description: Use of mouthwash containing chlorhexidine digluconate twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.

Intervention type: DRUG
Group type: OTHER
Intervention: Chlorhexidine digluconate
Description: Use of mouthwash containing chlorhexidine digluconate twice daily for 4 consecutive days instead of tooth brushing and usage of interdental cleaning devices.
Study: NCT04879771

Intervention type: PROCEDURE
Intervention: Receive gastrointestinal endoscopy
Description: patients receive gastrointestinal endoscopy in the morning or afternoon
Study: NCT06184022

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Augmented reality serious game design for promoting children's science education cognition:
Description: The experimental group utilized the three game lesson modules of the AR science education app designed for this study, including Animals vision,  Light transmission, and Color-Light mixing.~The experimental group's total learning time was limited to 20 minutes, the testing process was completed under the supervision of the instructor and the experimenter, and the children's behavioral characteristics were recorded. During the experiment, the participants were not disturbed in any way; researchers only intervened when they faced difficulties or requested assistance. The participants were given a 15-minute respite at the conclusion of the trial to take another POE test. Before and after the intervention, each participant's performance on the game was recorded.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Augmented reality serious game design for promoting children's science education cognition:
Description: The experimental group utilized the three game lesson modules of the AR science education app designed for this study, including Animals vision,  Light transmission, and Color-Light mixing.~The experimental group's total learning time was limited to 20 minutes, the testing process was completed under the supervision of the instructor and the experimenter, and the children's behavioral characteristics were recorded. During the experiment, the participants were not disturbed in any way; researchers only intervened when they faced difficulties or requested assistance. The participants were given a 15-minute respite at the conclusion of the trial to take another POE test. Before and after the intervention, each participant's performance on the game was recorded.
Study: NCT06528886

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hysterectomy by V-NOTES
Description: V-notes is like laparoscopy via the vaginal route.
Study: NCT05706753

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Milvexian will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Midazolam will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethinylestradiol
Description: Ethinylestradiol will be administered orally.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drospirenone
Description: Drospirenone will be administered orally.
Study: NCT06009133

Intervention type: PROCEDURE
Intervention: Conservative treatment
Description: Micronized purified flavonoid fraction, which is routinely used within indications in hemorrhoidal disease and recommended in ESCP and ASCRS guidelines, and licensed for use in hemorrhoidal disease by the Ministry of Health in our country, was given 2 g/day for one month.~Also, Conservative methods (fiber foods, warm shower, regulation of toilet habits, laxatives and nonsteroidal anti-inflammatory drugs) were recommended.

Intervention type: PROCEDURE
Intervention: Surgical Treatment
Description: While the patient was in the Jack-knife position, both hips were pulled laterally with tapes, appropriate visualization was obtained, the external thrombosed pack was excised under local anesthesia, and the wound was left to heal with secondary intention.Conservative methods were recommended in the surgical group as well as in the medical group.
Study: NCT05969054

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacosamide 100 mg
Description: Subjects who were randomly divided into group A took lacosamide for 6 months during treatment (initial dose was 50mg bid, maintained for one week and then increased to 100mg bid and maintained at this dose)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levetiracetam 250mg
Description: Subjects randomly divided into group B took levetiracetam for 6 months during treatment (initial dose was 250mg bid, maintained for one week and then increased to 500mg bid and maintained at this dose).
Study: NCT06328907

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: comprehensive rehabilitation therapy
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: comprehensive rehabilitation therapy
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-esophageal Tube Feeding
Description: The observation group was given enteral nutritional support with Intermittent Oro-esophageal Tube according to the following procedure: Before each feeding, inside and outside of the tube was cleaned with water. During feeding, the patient should maintain a semi-reclining or sitting position with mouth opened, and the tube was inserted slowly and smoothly into the upper part of the esophagus by medical staffs while the appropriate depth of intubation was checked with the calibration markings on the tube wall. The distance from the incisors to the head part of the tube should be between 22-25 cm. However, the specific depth should be evaluated based on patients' feedback and adjusted accordingly. After insertion, the tail part of the tube should be put into a container full of water and the absence of continuous bubbles indicated a successful intubation. Then, the feeding was to be conducted three times per day with 50 ml per minute and 400-600ml for each feeding.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric Tube Feeding
Description: The control group was given enteral nutritional support with Nasogastric Tube Feeding according to the relevant guidelines. Within 4 hours after admission, the placement of the feeding tube was conducted by professional medical staffs and after intubation, the tube was secured to the patient\&#39;s cheek with medical tape. The feeding was conducted once every 3-4 hours, with 200-300ml each time. The total feeding volume was determined based on daily requirements. The feeding content was formulated by the nutritionists based on the patient\&#39;s condition and relevant guidelines to reach the energy demand as 20-25 kcal/kg/day and protein supplementation of 1.2-2.0 g/kg/day for both two groups. For patients with limited tube feeding compliance, we made appropriate adjustments to ensure that they were not at risk of severe malnutrition as much as possible.
Study: NCT06477822

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sequence of manual therapy techniques
Description: Receive a sequence of manual therapy techniques composed by: suboccipital decompression technique, suboccipital release technique, fourth ventricle compression technique, vagus nerve neurodynamic technique

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Simulated manual therapy techniques
Description: Receive a sequence of simulated manual therapy techniques composed by four maneuvers without effect on autonomic nervous system
Study: NCT06026917

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toludesvenlafaxine hydrochloride sustained-release tablets
Description: D1\~D6, 40mg/ tablet, 1 tablet per time, once a day, D7\~D10, 80mg/ tablet, 1 tablet per time, once a day, D11\~D42, 80mg/ tablet, 2 tablets per time, once a day. For subjects who cannot tolerate 160mg, the dose may be reduced to 80mg/ dose once daily. After the number of subjects receiving 160mg/ dose reached 6, the remaining subjects received D11\~D42, 80mg/ tablet, one tablet each time, once a day.
Study: NCT05895188

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Glasses
Description: From the beginning to the end of the procedure, women will watch the selected nature video.
Study: NCT05142384

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mom-Net
Description: Mom-Net is a guided Internet intervention. Mom-Net is distinct from other CBT interventions for depression in addressing the link between maternal depression and parenting. Mom-Net's content includes core CBT skills taught in ways that are relevant to one's parenting interactions. Mothers will participate in Mom-Net with either high- or low-intensity coaching as determined by which version their HS was randomized to offer. Coaching is provided by HS staff.~In the high-intensity version, coaches provide support both for engaging with the intervention and for learning content. Coaching phone calls occur weekly (20-30 min call per session). In the low-intensity version, coaches provides supportive accountability for engaging with the intervention. Mothers participate in 4 (10-15) min calls occurring post-randomization, and 3- and 6-weeks later.

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual/Waitlist
Description: HS sites provide ongoing social and instrumental support to parents, including helping to connect families to needed services including community mental health providers. Additionally, research staff will provide lists of local mental health providers and information to support treatment seeking. Research staff will also provide National Crisis Lines for Mental Health Emergencies. Staff will inform participants to call research staff if they have trouble accessing services so that staff may provide additional help. Finally, staff will share a case note documenting referrals with the women's family service worker, so that worker may provide locally based assistance to the woman in accessing services. Subsequent to T2 assessment, participants in the TAU/Waitlist condition, will be offered the Mom-Net intervention variant (high- v low-intensity coaching) being provided by their respective HS agencies
Study: NCT04810754

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab Injection
Description: 1800 mg per injection; 8 consecutive injections once a week; subcutaneous application in abdomen
Study: NCT06598722

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BCL-2 inhibitors combined with the HyperCVAD regimen
Description: BCL-2 inhibitors combined with the HyperCVAD regimen for newly diagnosed adult T-ALL/LBL

Intervention type: OTHER
Group type: OTHER
Intervention: Propensity score matching historical data
Description: Propensity score matching was conducted with historical data (matching factors included age, gender, initial LDH levels, and the presence or absence of a large mediastinal mass at diagnosis) to compare the advantages and disadvantages of the experimental regimen with previous induction treatment protocols.
Study: NCT06063785

Intervention type: DIAGNOSTIC_TEST
Intervention: Acoustic Radiation Forced Impulse Imaging
Description: Measurement of Liver stiffness

Intervention type: DIAGNOSTIC_TEST
Intervention: Acoustic Radiation Forced Impulse Imaging
Description: Measurement of Liver stiffness

Intervention type: DIAGNOSTIC_TEST
Intervention: Acoustic Radiation Forced Impulse Imaging
Description: Measurement of Liver stiffness

Intervention type: DIAGNOSTIC_TEST
Intervention: Multispectral Optoacoustic Tomography
Description: Measurement of optoacoustic spectra in liver and gastrointestinal tract

Intervention type: DIAGNOSTIC_TEST
Intervention: Multispectral Optoacoustic Tomography
Description: Measurement of optoacoustic spectra in liver and gastrointestinal tract

Intervention type: DIAGNOSTIC_TEST
Intervention: Multispectral Optoacoustic Tomography
Description: Measurement of optoacoustic spectra in liver and gastrointestinal tract
Study: NCT04752982

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: c-SIGHT intervention
Description: The c-SIGHT active intervention involves grasping, lifting and balancing wooden rods using the unaffected hand. C-SIGHT uses a training mat, three wooden rods of different lengths, a laptop (to run the computer program) and a small motion tracking sensor which records the user's session length and trials completed. The participant's existing television is used to present the program (connected to the laptop).

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: c-SIGHT attentional control
Description: The c-SIGHT attentional control exercises involves grasping and lifting wooden rods from one end using the unaffected hand. Identical to the intervention group, the c-SIGHT attentional control version uses a training mat, three wooden rods of different lengths, a laptop (to run the computer program) and a small motion tracking sensor which records the user's session length and trials completed. The participant's existing television is used to present the program (connected to the laptop).
Study: NCT06328751

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Case group
Description: Meditation will be taught through a video played on a Samsung® gear VR virtual reality glasses with monitoring of the patient's vital signs by the Samsung® smart watch to promote better quality of life and control cancer pain in patients treated at the Pain Therapy and Palliative Care Service.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active control group
Description: Meditation will be taught through a video played on a Samsung® cell phone with monitoring of the patient's vital signs by the Samsung® smart watch to promote better quality of life and control cancer pain in patients treated at the Pain Therapy and Palliative Care Service.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Passive control group
Description: Meditation will be taught through a audio played on a Samsung® cell phone with monitoring of the patient's vital signs by the Samsung® smart watch to promote better quality of life and control cancer pain in patients treated at the Pain Therapy and Palliative Care Service.
Study: NCT05569720

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ApTOLL
Description: ApTOLL will be administered as follows:~* Day 1: a dose of 0.1mg/kg will be administered intravenously as a slow infusion.~* Day 2: a dose of 0.1mg/kg will be administered intravenously as single bolus injection.~* Day 3: a dose of 0.2mg/kg will be administered intravenously as single bolus injection.
Study: NCT04993612

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood gas analysis
Description: Two blood samples will be drawn from the wedge position, behind the inflated balloon, during the right heart catheterization, and blood gas analyses will be performed. First sample will be drawn directly after inflating the ballon, and the second one 2 minutes later.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood gas analysis
Description: Two blood samples will be drawn from the wedge position, behind the inflated balloon, during the right heart catheterization, and blood gas analyses will be performed. First sample will be drawn directly after inflating the ballon, and the second one 2 minutes later.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood gas analysis
Description: Two blood samples will be drawn from the wedge position, behind the inflated balloon, during the right heart catheterization, and blood gas analyses will be performed. First sample will be drawn directly after inflating the ballon, and the second one 2 minutes later.
Study: NCT06506812

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: High-Dose Influenza Vaccine
Description: For this arm, the high-dose quadrivalent influenza vaccine Efluelda®/Fluzone® High-Dose Quadrivalent will be used.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard-Dose Influenza Vaccine
Description: Any standard-dose quadrivalent influenza vaccine administered in the governmental influenza vaccine programs may be used.
Study: NCT06333262

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pirtobrutinib
Description: Initial treatment:~- Pirtobrutinib 200 mg by mouth (PO) daily from Cycle 1 Day 1 until the end of Cycle 12. Each cycle is 28 days.~Re-treatment:~-Pirtobrutinib 200 mg PO daily continuously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Obinutuzumab is given intravenously from Cycle 7 to Cycle 12, for total 6 cycles during initial treatment only.~Initial treatment:~- Obinutuzumab intravenous (IV) following the standard schedule from Cycle 6 through Cycle 12 (total 6 cycles: 100 mg on Cycle 6 Day 1, 900 mg on Cycle 6 Day 2, 1000 mg on Cycle 6 Day 8 and Cycle 6 Day 15, 1000 mg on Day 1 of Cycle 7 through Cycle 12).
Study: NCT05155163

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SC-POWR
Description: Patients assigned to SC-POWR receive 12 Cognitive Behavioral Therapy (CBT) sessions over 24 weeks.
Study: NCT06071247

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D printed models
Description: 3D printed simulation models of the stomach, duodenum, common bile duct, and pancreatic duct structures using a combination of soft and hard materials