TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05020236

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elranatamab
Description: subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elranatamab
Description: subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab / hyaluronidase, subcutaneous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab / hyaluronidase, subcutaneous

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Daratumumab
Description: Daratumumab / hyaluronidase, subcutaneous

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pomalidomide
Description: oral

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: oral
Study: NCT05347849

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BPL-003
Description: A single dose of BPL-003 will be administered intranasally

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A single dose of placebo will be administered intranasally
Study: NCT06034145

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT04640805

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein supplementation
Description: Liquid protein fortifier (Similac) will be added at 1ml per 25ml of PDHM at 130ml/kg/day of feed volume.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Analysis with Miris Human Milk Analyzer
Description: PDHM macronutrient content will be analyzed using the Miris Human Milk Analyzer and PDHM with fat content of 3.8g/dL or higher will be selected and provided.
Study: NCT05546021

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: NOL monitor
Description: NOL technology uses a multiparameter-based sensor platform, and advanced algorithm, to continuous monitor Autonomic Nervous System (ANS) functions. NOL reflects a patient's nociceptive state and analgesic effect, helping to optimize the administration of systemic and/or regional analgesics and avoiding overdose or underuse of these drugs.~The nociception level is a multiparameter monitor that combines information from the finger photoplethysmogram amplitude, skin conductance, skin conductance fluctuation, heart rate, heart rate variability, and their time derivatives into one index ranging from 0 (absence of noxious stimulation) to 100 (severe noxious stimulation). The nociception level is a composite score derived from a set of physiologic variables (i.e., peripheral effectors of the autonomous nervous system): heart rate, heart rate variability, the amplitude of the photoplethysmogram, skin conductance, skin conductance variability, and the time derivatives of these variables.
Study: NCT05916794

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Cervical Retraction Exercises (MCRE)
Description: Group A includes Modified cervical retraction exercise The patient is in sitting OR standing position and faces the physical therapist. The MCRE program consisted of alternating head position( neutral, side bending and rotation) while pushing their chin backward patients maintained an upright posture and tried to pull back their shoulders while maintaining this retracted position patient side bend OR rotate their head respectively hold the position for 20 sec.subject performed 5 sets of 10 repetition for 3-4 days per week. Rest intervals of 30 seconds were provided after the completion of 10 repetitions for each pattern and between sets, respectively. The total duration of MCRE will be of approximately 15-20 minutes

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Control therapeutic exercise(MCTE)
Description: Motor control therapeutic exercises will be guided for the retraining of cervical muscles.it include craniocervical flexor exercise,craniocervical extensor exercise, co-contraction of flexors and extensor, a synergy exercise for retraining the strength of the deep neck flexors. Each of these four exercises will be performed for 3 sets of 8 to 10 repetitions, taking an approximate total duration of 15-20 minutes for, 3 days a week
Study: NCT05421572

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibrotouch
Description: Fibrotouch will be performed showing the stiffness and fat content of liver
Study: NCT05870683

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegoprazan
Description: Included in dual eradication medication.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: Included in dual eradication medication.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin
Description: Included in dual eradication medication.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Esomeprazole
Description: Included in dual eradication medication.
Study: NCT05291403

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical thoracoscopic cryotherapy combined with standard first-line therapy for advanced non-cell lung cancer
Description: Medical thoracoscopic cryotherapy: medical thoracoscopy biopsy hole insert bendable freezing probes, place the frozen probe placed in the center of the tumor at the top will be frozen carbon dioxide gas source pressure adjustment to the bar of 50-60 bar, tread down switch, foot pedal to start the probe, after about 30 s at the top of the probe to form a ice hockey, local tissue after frozen white, sometimes a small amount of bleeding; Fix the probe, loosen the pedal, and wait 30 seconds for automatic melting and rewarming (bleeding probability is low after full rewarming). Freeze 5 to 10 at a time.~In addition, all patients were treated with standard first-line regimens according to guidelines of non small cell lung cancer (NSCLC) and Eastern Cooperative Oncology Group (ECOG) scores.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sequential intrathoracic injection of cisplatin/erythromycin combined with standard first-line therapy for advanced non-cell lung cancer
Description: The pleural effusion was fully drained and cisplatin 40mg/m2 was given, dissolved in 100mL 0.9% sodium chloride (NaCl) solution 100 mL, then injected into the pleural cavity and retained for 24 hours. Erythromycin was sequentially injected into the thorax to seal the pleural cavity.~In addition, all patients were treated with standard first-line regimens according to guidelines of NSCLC and ECOG scores.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard first-line therapy for advanced non-cell lung cancer without intrathoracic treatment
Description: Only intrathoracic tube was used to drain pleural effusion, and local pleural cavity was not treated.~In addition, all patients were treated with standard first-line regimens according to guidelines of NSCLC and ECOG scores.
Study: NCT06092307

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Bioelectrical impedance
Description: Resistance, reactance, phase angle,free-fat mass, body cell mass, body cell mass index and total body will be recorded

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Handgrip strength test
Description: Handgrip strength test using a hydraulic hand dynamometer and sit-to-stand test will be performed.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: muscle ultrasound.
Description: The following ultrasound parameters will be evaluated: radial, ulnar, rectus femoris, rectus abdominis and medial gastrocnemius muscle thickness and echo intensity with gray-scale-index; rectus femoris muscle cross sectional area; gastrocnemius muscle fiber length and pennation angle.
Study: NCT05118867

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iPREPARED
Description: iPREPARED is a mobile health technology that can be accessed via the web, tablet, or phone. It contains a preparatory video that outlines what to expect during the hospitalization. Instructional videos and examples are provided for the patient and their recovery partner to use to do their own reorientation, distraction techniques, physical activity, and sleep hygiene.
Study: NCT06160375

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: pain assessment after video assisted thoracoscopic lung surgeries
Description: a scalp needle with an extended tube will be inserted into the paravertebral space at the T4 level under thoracoscopic direct vision before closing the chest. One centimeter adjacent to the vertebrae will be inserted vertically 0.5 cm under the parietal pleura with the needle, and 20 ml 0.25% bupivacaine will be injected then the field will be observed for 5 min to make sure that there is no hemorrhage or hematoma.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: pain assessment after video assisted thoracoscopic lung surgeries
Description: a scalp needle with an extended tube will be inserted into the paravertebral space at the T4 level under thoracoscopic direct vision before closing the chest. One centimeter adjacent to the vertebrae will be inserted vertically 0.5 cm under the parietal pleura with the needle, and 20 ml 0.25% bupivacaine will be injected then the field will be observed for 5 min to make sure that there is no hemorrhage or hematoma.
Study: NCT06356883

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IA Carboplatin + IA Caelyx
Description: Intraarterial infusion of carboplatin combined with liposomal doxorubicin
Study: NCT05484284

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: two-stage primary total knee arthroplasty with low-dose antibiotics
Description: Briefly, investigators completely debrided all necrotic soft tissue in the first stage of the operation. The surgical site was flushed twice with hydrogen peroxide, iodine, and saline solutions. Then, the antibiotic-loaded cement spacer was inserted. After surgery, a 10-day course of intravenous organism-specific antibiotics or vancomycin was administered, followed by oral antibiotic therapy. Second-stage reimplantation was performed once there was no sign of infection. The spacer was removed and the new prosthesis was implanted without the use of antibiotic-containing bone cement.
Study: NCT05548985

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midodrine Oral Tablet
Description: oral midodrine tablet (5 mg) 90 min before performing spinal block

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Metoclopramide
Description: oral placebo (metoclopramide 10 mg tablet). 90 min before performing spinal block
Study: NCT06356883

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IA Carboplatin + IA Etoposide Phosphate
Description: Intraarterial infusion of carboplatin combined with etoposide phosphate
Study: NCT06105723

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pathway to Healthy Aging care
Description: The ICOPE-based personalized care planning comprises two home visits. In 1st visit, a comprehensive assessment proposed by the WHO-ICOPE model is conducted to identify eight possible health problems including malnutrition, reduced physical fitness, fall risk, cognitive decline, insomnia, pain, psychological distress and social loneliness. After health problem identification, each participant receives a personalized care prescription. 2nd visit adopts a goal-oriented empowerment 3-step cycle to personalize the care planning: 1) communicating assessment results to increase healthy self-awareness; 2) supporting setting person-directed goals to address health problems; 3) identifying health actions and personalizing goal setting to participants' contexts. The 12-week healthy aging empowerment comprises three core activities for healthy aging promotion, including interactive health education, health message broadcasts, and three case conferences for goal monitoring and health counseling.
Study: NCT06068556

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GamCovidVac-M vector vaccine for the prevention of COVID-19 with altered antigenic composition
Description: Two intramuscular injections of GamCovidVac-M vector vaccine for the prevention of COVID-19 with altered antigenic composition will be performed. 1st injection - component I, 2nd injection - component II.
Study: NCT04580264

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REINTERVENTION
Description: This self-applied online program will take three months and comprise 9 behavioural modules developed gradually, achieving the changes needed on eating and physical activity habits, supported by audiovisual instructions given by an hypertension specialist doctor.
Study: NCT05843747

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sampling
Description: During thier bariatric surgery, samples of adipose tissue will be done
Study: NCT06326294

Intervention type: DEVICE
Group type: OTHER
Intervention: Thermal ablation
Description: Thermal ablative uses heat (100°C to 120°C) to cause localized tissue damage at the cervical transformation zone and destroy the abnormal epithelium.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: LOOP ELECTROSURGICAL EXCISION PROCEDURE
Description: Cervical tissue excision
Study: NCT05582668

Intervention type: PROCEDURE
Intervention: Bariatric surgery
Description: Bariatric surgery
Study: NCT05749042

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: Concurrent Chemoradiotherapy Based of Cisplatin Plus Sintilimab.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiotherapy
Description: Concurrent Chemoradiotherapy Based of Cisplatin
Study: NCT05794178

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: Education about health benefits of physical activity, 2018 US Physical Activity Guidelines, assigned goals tailored to baseline step counts, and worksheet to develop action and coping plans (three of each)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Education about health benefits of physical activity, 2018 US Physical Activity Guidelines, assigned goals tailored to baseline step counts, and worksheet to develop action and coping plans (three of each)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: Education about health benefits of physical activity, 2018 US Physical Activity Guidelines, assigned goals tailored to baseline step counts, and worksheet to develop action and coping plans (three of each)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Activity tracker
Description: Fitbit activity tracker and mobile app to provide ad libitum behavioral feedback and self-regulatory support

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Activity tracker
Description: Fitbit activity tracker and mobile app to provide ad libitum behavioral feedback and self-regulatory support

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Activity tracker
Description: Fitbit activity tracker and mobile app to provide ad libitum behavioral feedback and self-regulatory support

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Text messaging (random timing and selection)
Description: Four text messages/day at random times within a participant's availability window and drawn at random from one of three content libraries (move more \[40%\], sit less \[40%\], inspirational quotes \[20%\])

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text messaging (precision dosing)
Description: Up to four text messages/day within a participant's availability window, timed and selected from one of three content libraries (move more, sit less, inspirational quotes) based on a person-specific dynamic model and contextual data
Study: NCT04420260

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Group A: oropharygeal spray and immunostimulant emulsion
Description: Intervention 1: Preparation in a liquid solution to be used for oropharyngeal spray, composed of 3 natural bioactive substances of routine use in humans, that feature homologous molecular structures to the native viral receptor.~Intervention 2. Preparation in an emulsion functional food presentation for oral administration, that contains the 8 bioactive compounds that have demonstrated antiviral activity and modulation of the inflammatory response recognized at the moment in the immune activation against the virus.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Group D:Placebo oropharyngeal spray + Placebo taken PO
Description: Intervention 1: Preparation in a liquid solution to be used for oropharyngeal spray, composed of Placebo substances of routine use in humans.~Intervention 2. Preparation in an emulsion presentation for oral administration that contains the Placebo compounds
Study: NCT06259682

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Paradoxical Intention
Description: Paradoxical intention (PI). PI is described as instructing patients with sleep onset insomnia to try to remain awake for as long as possible rather than to focus on trying to fall asleep
Study: NCT06129929

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hospital Jujutsu Group, HJJ Group
Description: The aim of this study, procedures, methodology, and the subject's rights were well explained to the eligible nursing staff according to the informed consent form. Written informed consent was obtained from each participant before data collection.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Hospital Jujutsu Group, HJJ Group
Description: The aim of this study, procedures, methodology, and the subject's rights were well explained to the eligible nursing staff according to the informed consent form. Written informed consent was obtained from each participant before data collection.
Study: NCT06277648

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PENG block
Description: PENG block was performed by the primary investigator (B.C) following proper skin disinfection with the patient in the supine position. Under the guidance of a low-frequency curvilinear ultrasound probe, the iliopubic eminence and the psoas tendon were identified, and local anaesthetic as 30 mL 0.375% bupivacaine was injected between the periosteum and psoas tendon following negative aspiration.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SIFIB
Description: The high-frequency linear probe was placed medial to the anterosuperior iliac spine in a parasagittal orientation to visualize the bow tie appearance formed by the sartorius's internal oblique and iliacus muscles. The needle tip was placed under fascia iliaca through an in-plane approach, and local anaesthetic as 30 mL 0.375% bupivacaine was injected from the caudad to the cephalic direction.
Study: NCT06508008

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: continuous negative pressure suction
Description: (1) Open the mouth with a tongue depressor; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) Insert a suction tube into the mouth to aspirate phlegm.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intermittent negative pressure sputum suction through oral pharyngeal airway
Description: (1) Insert the oropharyngeal airway parallel into the oral cavity; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) The suction tube is inserted into the deep oral cavity through the middle lumen of the oropharyngeal airway; (4) Intermittent negative pressure for suction and suction of sputum
Study: NCT05754593

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Anti-Mullerian hormone (AMH) level
Description: Measure of Anti-Mullerian hormone (AMH) level by blood sample

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-Mullerian hormone (AMH) level
Description: Measure of Anti-Mullerian hormone (AMH) level by blood sample

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Antral follicle count (AFC)
Description: Measure of Antral follicle count (AFC) by ultrasound imaging

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Antral follicle count (AFC)
Description: Measure of Antral follicle count (AFC) by ultrasound imaging

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical assessment
Description: MS history and MS treatments and Expanded Disability Status Scale (EDSS) score will be recorded
Study: NCT05957614

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Traditional rehabilitation protocol
Description: Rehabilitation protocol after open surgery for Achilles tendon rupture, including immobilization, early weightbearing ankle motion exercise and isolated early ankle motion exercises.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture-assisted Rehabilitation Protocol
Description: Add acupuncture treatment on the basis of traditional rehabilitation protocol.The acupuncture procedure is as follows, acupuncture treatment is carried out for half an hour every day in two weeks after surgery. The acupoints on the affected side are ST36(ZuSanLi), GB34(YangLingQuan) and SP9(YinLingQuan), and the acupoints on the healthy side are Ki3(TaiXi), bl60(KunLun) and PC7(DaLing).
Study: NCT05754151

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MAYA Mobile Application
Description: The mobile cognitive behavioral therapy (CBT) application, MAYA, teaches cognitive behavioral therapy (CBT) techniques including emotion monitoring, cognitive restructuring, mindfulness, exposure and psychoeducation (i.e. information about anxiety and depression). The application includes an interactive dashboard to provide the user with statistics for tracking progress toward their goals. Although the MAYA application is new, its content and structure are similar to how CBT- a well-established and widely used psychosocial intervention - is commonly delivered in the more traditional setting of a psychotherapist's office.
Study: NCT05934331

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM302+Toripalimab
Description: LM-302 in combination with Toripalimab.
Study: NCT05044754

Intervention type: PROCEDURE
Intervention: Local treatment of the prostate (SCAP or HIFU)
Description: Once the local involvement of the recurrent prostate cancer is confirmed, patient will undergo local treatment of the prostate (SCAP or HIFU)

Intervention type: PROCEDURE
Intervention: Local treatment of the prostate (SCAP or HIFU)
Description: Once the local involvement of the recurrent prostate cancer is confirmed, patient will undergo local treatment of the prostate (SCAP or HIFU)
Study: NCT05920772

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: KickAsh! intervention
Description: The general aim of the KickAsh! intervention is to prevent smoking initiation in adolescents living in vulnerable socioeconomic situations. The intervention exists of different components concerning smoking prevention. Most components have a direct influence on smoking initiation by affecting several determinants of the adolescents. These components include smoke-free games, mood boards, a smoke-free camp, the Kick some Ash!-challenge and exercises concerning self-efficacy and skills. Yet, some of the components target adolescents by influencing their environment, i.e. smoking policy in the organisation and youth workers as role models. All components are developed using a combination of theoretical methods to change or influence these determinants or environmental factors.