TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05578755

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Goal-setting
Description: In the control condition participants set goals (as in the intervention conditions), but receive no further guidance.
Study: NCT06217952

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SPL84
Description: SPL84 solution for nebulization

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo solution for nebulization
Study: NCT05541601

Intervention type: OTHER
Intervention: Blood and Urine samples
Description: The samples will be used to identify a range of tests (including genetic, protein and other biomarkers), which along with the clinical data will hopefully identify those most at risk of developing HCC, and to identify HCC at the earliest possible time points.
Study: NCT05488652

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time restricted eating
Description: not more than 10 hrs. eating window daily goal for 6 months
Study: NCT05634421

Intervention type: OTHER
Intervention: E-learning
Description: The E-learning is under development at the department of Dermatology from MUMC+.

Intervention type: OTHER
Intervention: E-learning
Description: The E-learning is under development at the department of Dermatology from MUMC+.

Intervention type: OTHER
Intervention: E-learning
Description: The E-learning is under development at the department of Dermatology from MUMC+.

Intervention type: OTHER
Intervention: E-learning
Description: The E-learning is under development at the department of Dermatology from MUMC+.

Intervention type: OTHER
Intervention: E-learning
Description: The E-learning is under development at the department of Dermatology from MUMC+.
Study: NCT05415826

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: slow-release dexamethasone implant
Description: The eyes with proliferative diabetic retinopathy underwent PPV with silicone oil filling with or without slow-release dexamethasone implant at the end of surgery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: slow-release dexamethasone implant
Description: The eyes with proliferative diabetic retinopathy underwent PPV with silicone oil filling with or without slow-release dexamethasone implant at the end of surgery.
Study: NCT06171113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Doses administrated orally with 240 mL of water.
Study: NCT06384404

Intervention type: OTHER
Intervention: Questionnaire
Description: PROMIS questionnaire
Study: NCT06485492

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Implant an aneurysm embolization system
Description: The product uses minimally invasive interventional method to treat intracranial aneurysms approved for application. The study physician selects the appropriate size and/or shape of the aneurysm based on the size and shape of the intracranial arterioma. The aneurysm embolization system device is inserted into the arterioma through a compatible neurovascular microcatheter.
Study: NCT06538168

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Self-Management Education (DSME)
Description: The intervention, Diabetes Self-Management Education (DSME), involves a structured educational program including daily reminders regarding medication, and foot care, educational-led video weekly, and handouts for the management od diabetes and foot care to enhance knowledge and skills in managing diabetes and preventing complications like diabetic foot ulcers (DFUs).
Study: NCT05200507

Intervention type: DEVICE
Intervention: High Frequency Percussive Ventilation
Description: High Frequency Percussive Ventilation will be applied for 10 minutes at an oscillation frequency of 10 Hz, superimposed to the ventilatory assistance
Study: NCT06537882

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: G-NiiB synbiotics formula (SLP07)
Description: SLP07 consists of a blend of food-grade Bifidobacterium and Lactobacillus as active probiotics, omega 3, and vitamin E.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Active placebo
Description: Active placebo contains 2mg of vitamin C with corn starch filler
Study: NCT04981626

Intervention type: OTHER
Intervention: Clinical and experimental session
Description: Psychologic profile with standardized interview and scales (see below for details: SCID, BDI, STAI, BPQ, EDE Q, Pictorial Body Image Scale (PBIS) and EDI).~Measure the stomach-brain synchrony during EEG/EGG resting state, the distribution of voluntary actions across the respiratory phase, and the distribution of saccadic eye movements across the cardiac-cycle.

Intervention type: OTHER
Intervention: Clinical and experimental session
Description: Psychologic profile with standardized interview and scales (see below for details: SCID, BDI, STAI, BPQ, EDE Q, Pictorial Body Image Scale (PBIS) and EDI).~Measure the stomach-brain synchrony during EEG/EGG resting state, the distribution of voluntary actions across the respiratory phase, and the distribution of saccadic eye movements across the cardiac-cycle.
Study: NCT05066074

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Distal Radial Vascular Access
Description: Distal Radial Vascular Access

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Distal Radial Vascular Access
Description: Distal Radial Vascular Access
Study: NCT06171113

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Doses administrated orally with 240 mL of water.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Doses administrated orally with 240 mL of water.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Doses administrated orally with 240 mL of water.
Study: NCT06531954

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vagus nerve stimulation
Description: Vagus nerve stimulation group: Vagus stimulation was applied bilaterally through the ear. taVNS was performed with the Vagustim device. The stimulation pulse width was 300 microseconds, the frequency was 10 Hz, and it was biphasic with a 20-minute duration. Electrodes were placed on the concha and tragus parts of the ear, and the current was increased through these electrodes until the participant felt pain.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Breathing exercise
Description: Breathing exercise group: The content of breathing exercises was planned as thoracic expansion exercises. These exercises were applied to the lower, middle, and upper lobes in 3 sets of 3x10 (90 times breathing in one area) and lasted for an average of 20 minutes. Participants were asked to inhale as deeply as possible into the relevant area, hold their breath for 3 seconds, and then slowly exhale the entire breath.
Study: NCT05504460

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03
Description: Treatments in the test group will lasts for 12 months, and symptomatic treatment will be provided based on the actual symptoms of the subjects. Subjects in the test group will be required to receive inhalation for at least 4 days every 7 days with at least 3780L inhaled every 7 days (It is recommended to inhale at least 540L per day; If the flow rate is 3L/min, it is recommended that the cumulative inhalation time should be at least 3 hours per day. If the flow rate is 1.5L/min, it is recommended that the cumulative inhalation time should be at least 6 hours per day).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: basic treatment
Description: supportive treatment determined by the investigator based on the condition of the patients

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: basic treatment
Description: supportive treatment determined by the investigator based on the condition of the patients
Study: NCT04547972

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Higher-load resistance training
Description: This intervention will have one arm and one leg of each participant training with \~80% of their one repetition maximum

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lower-load resistance training
Description: This intervention will have one arm and one leg of each participant training with \~30% of their one repetition maximum
Study: NCT04864015

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Mouthpiece B1(Mouthpiece MPC-ST GMDN:62534 Generic name: Endoscopic bite block, basic, reusable
Description: Use of a Mouthpiece B1 during standard EGD instead of a conventional mouthpiece

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mouthpiece B1(Mouthpiece MPC-ST GMDN:62534 Generic name: Endoscopic bite block, basic, reusable
Description: Use of a Mouthpiece B1 during standard EGD instead of a conventional mouthpiece
Study: NCT04956718

Intervention type: OTHER
Group type: OTHER
Intervention: Cold Pressor Test (CPT)
Description: Cold Pressor Test (CPT): apparatus for the task is a tank of water of temperature of 4 °C (+-0.5 °C), with instruction to immerse the hand until too uncomfortable to continue. A maximum time limit per immersion of 3-5 min is applied. Quantitative measurement can then be made of pain threshold (point first perceived as painful) and tolerance time.

Intervention type: OTHER
Group type: OTHER
Intervention: Cold Pressor Test (CPT)
Description: Cold Pressor Test (CPT): apparatus for the task is a tank of water of temperature of 4 °C (+-0.5 °C), with instruction to immerse the hand until too uncomfortable to continue. A maximum time limit per immersion of 3-5 min is applied. Quantitative measurement can then be made of pain threshold (point first perceived as painful) and tolerance time.

Intervention type: OTHER
Group type: OTHER
Intervention: Placebo NaCl Nasal spray
Description: placebo nasal spray containing NaCl solution

Intervention type: OTHER
Group type: OTHER
Intervention: Placebo NaCl Nasal spray
Description: placebo nasal spray containing NaCl solution
Study: NCT05105087

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Perflubutane Microbubble
Description: Given subdermally

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Contrast-Enhanced Ultrasound
Description: Undergo ultrasound
Study: NCT05301166

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Technology Based Motivation Education Program
Description: Technology-Based Motivation Education Program consists of web-based education, motivation program and individual motivation interviews. This program will be prepared according to the Health Belief Model (HBM). It will be applied for 4 months. Participants will take a pre-test before starting the program and a post-test at the end of the program. Individual motivation interviews will be 6 sessions in total. A website will be prepared for the Technology Based Motivation Education Program. This website consists of two parts, a web-based education and motivation program for obesity. The motivation program will enable the participant to follow the program and receive motivational messages.

Intervention type: OTHER
Group type: OTHER
Intervention: Web Based Education
Description: Students in the control group will participate in web-based educations on obesity prepared only according to the Health Belief Model in the Technology-Based Motivation Education Program. Individual interviews supporting web-based education will be held with the control group once a month.
Study: NCT05499507

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: COH
Description: Incorporates two, evidence-based individual-level interventions (home blood pressure telemonitoring coupled with the interactive obesity treatment approach, that includes nutrition and physical activity text messages with tailored feedback) and an institutional-level intervention (anti-racism training of providers and staff along with patient feedback to inform respectful care).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COH+
Description: Includes all components of COH plus interpersonal support for Black women by Black women (community doula care, mental health services, and lactation support).
Study: NCT05379400

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Portable air cleaner (PAC)
Description: Commercially available Portable air cleaners (PAC) contain carbon filters that reduce volatile organic carbons and can reduce odors. Because of this, the researchers will remove the carbon filters from all air purifiers to preserve blinding. This will be done by unblinded research staff and devices will be labelled with an ID number to preserve blinding of the rest of the research team.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Portable air cleaner (PAC)
Description: Sham Portable air cleaner (PAC) are commercially available portable air cleaners with the carbon filters and the HEPA filters removed. This will be done by unblinded research staff and devices will be labelled with an ID number to preserve blinding of the rest of the research team.
Study: NCT04874766

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Wingate exercise test and on-ice testing while wearing a face mask
Description: Power output during 2 x 20s Wingate cycle tests and total distance during an on-ice skating test while wearing a face mask

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Wingate exercise test and on-ice testing while wearing a sham face mask
Description: Power output during 2 x 20s Wingate cycle tests and total distance during an on-ice skating test while wearing a face mask
Study: NCT05674994

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisone/Prednisone
Description: Patients will be enrolled during their hospitalization in pneumology department, as part of current practice, within 7 days of the screening visit. The investigator will perform randomization by connecting to the eCRF, randomization be stratified for the severity of IPF and the treatment with antifibrotic therapy (Nintedanib or Pirfenidone) (yes/no).~If patient is randomized in Glucocorticoids Group:~* Day 1, 2 and 3: Intravenous Methylprednisolone 10 mg/kg/d (without exceeding 1000 mg/d). Vials of injectable solution of methylprednisolone® are diluted in 100 ml of NaCl 0.9% or G5%. Perfusion duration is between 20 to 30 minutes.~* From day 4 to Day 30: Oral Prednisone slow tappering~  * 1 mg/kg/d for 7 days~ * 0.5 mg/kg/d for 7 days~ * 0.25 mg/kg/d for 7 days,~ * 10 mg/d until Day 30. For 10mg/kg, 1 mg/kg, 0.5 mg/kg, 0.25 mg/kg; rounding to 5 decimal lower if decimal ≤ 7 and the top ten if decimal ≥ 8.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will be enrolled during their hospitalization in pneumology department, as part of current practice, within 7 days of the screening visit. The investigator will perform randomization by connecting to the eCRF, randomization be stratified for the severity of IPF and the treatment with antifibrotic therapy (Nintedanib or Pirfenidone) (yes/no).~If patient is randomized in Placebo Group:~Day 1, 2 and 3: Intravenous Methylprednisolone-Placebo From Day 4 to Day 30: Oral Prednisone-Placebo The Methylprednisolone-Placebo corresponds to 100 ml of NaCl 0.9 % or G5%. Perfusion duration is between 20 to 30 minutes.~For the Prednisone-Placebo, the placebo was an oral solution formulated with a bittering agent (pharmaceutical excipient). Specifically, in place of prednisone, sucrose octaacetate (defined as a GRAS-'Generally Recognized as Safe' excipient by the EMA) was used at 5 mg/mL.
Study: NCT06299891

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phentermine / Topiramate Extended Release Oral Capsule [Qsymia]
Description: To assess safety and maximum tolerated dose as well as efficacy on weight loss of Phentermine/Topiramate in individuals with hypothalamic obesity.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: To assess safety and maximum tolerated dose as well as efficacy on weight loss of placebo treatment in individuals with hypothalamic obesity.
Study: NCT06201923

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Honey Mouthwash
Description: 0.2% thyme honey mouth rinse

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: 0.9% sodium chloride
Study: NCT05736757

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tissue Plasminogen Activator
Description: Injection of 50 ug tissue plasminogen activator into the suprachoroidal cavity or subretinal space to assist in bleeding liquefaction
Study: NCT04755114

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Turkish Music
Description: Turkish Music;In choosing the music, patients will be asked about their favorite vocalist and music pieces before the procedure. The researcher will then download these music pieces from YouTube and create a 30-minute list and listen to patients.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: comedy movie
Description: Prior to the research, attention will be paid to the selection of comedy films that do not contain violence, swearing and obscene scenes that may adversely affect patients. Prior to the research, attention will be paid to the selection of comedy films that do not contain violence, swearing and obscene scenes that may adversely affect patients. In the selection of comedy films, the opinions of two experts from Mimar Sinan University, Faculty of Fine Arts, Department of Cinema and Television and İnönü University will be preferred, and the films Kemal Sunal and Şener Şen, one of the actors that Turkish people know closely, laugh most and have settled into their culture, will be preferred.
Study: NCT05459051

Intervention type: DIAGNOSTIC_TEST
Intervention: Rest-angina physiological assessment
Description: The degree of stenosis required to cause angina at rest will be measured under double-blinded placebo controlled conditions using sequential intracoronary balloon inflations. This will then be correlated with various physiological indices, including FFR and NHPR.

Intervention type: DIAGNOSTIC_TEST
Intervention: Exercise-angina physiological assessment
Description: The degree of stenosis required to cause angina during exercise will be measured under double-blinded placebo controlled conditions using sequential intracoronary balloon inflations. This will then be correlated with various physiological indices, including FFR and NHPR.
Study: NCT04495465

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Radial Shock Wave Therapy
Description: 2000 shots of extracorporeal radial shock waves therapy on neck muscles at 4bars and 10 Hertzs

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Manual Therapy
Description: 25 minute massage to neck muscles

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy
Description: 25 minute massage to neck muscles

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo shock waves
Description: 3 minutes of placebo extracorporeal radial shock waves therapy on painful points of neck muscles.
Study: NCT06530992

Intervention type: OTHER
Intervention: tucking break
Description: All participants will provide a semen sample for sperm analysis after 2-7 days of abstinence from ejaculation, a venous blood sample will be taken at the same time, and quality of life will be assessed using a questionnaire.~Participants in the study group are then asked to refrain from tucking or wearing tight underwear for at least 73 days. At least 73 days (10.5 weeks) after the first spermiogram, another semen collection is scheduled after 2-7 days of abstinence from ejaculation for the preparation of a spermiogram, a venous blood sample is taken at the same time, and quality of life is assessed in all participants. At this point, depending on the participant's wishes, it is possible to perform sperm cryopreservation for fertility preservation before starting gender affirming hormonal treatment.
Study: NCT05253898

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor Physical Therapy
Description: Purpose of pelvic floor muscle education program is reduce the symptoms of stress urinary incontinence and improving quality of life.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic Yoga Training
Description: Purpose of this group show the effectiveness of yoga therapy on stress urinary incontinence and quality of life.
Study: NCT06099171

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol and β-Caryophyllene Patch
Description: Cannabidiol with its decongestant activity has a soothing action in the area of application, thanks to the association with B-caryophyllene which assists its activity

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen-Ozone Therapy
Description: Ozone (O3) is a molecule consisting of 3 atoms of oxygen in a dynamically unstable structure. O3 has the capacity to modulate inflammation. O3 when in contact with human fluids and tissues rapidly reacts, generating many reactive oxygen species, as hydrogen peroxide (H2O2), superoxide ion, and hydroxyl radical (OH-). It is suggested that through moderate oxidative stress generated by these reactive byproducts, O2O3 might produce positive effects in several pathologies, including musculoskeletal affections. Moreover, O2/O3 may directly regulate prostaglandins (PGS) and bradykinin, and suppress several proinflammatory mediators, such as IL-6, IL-8 and TNF-α

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oxygen-Ozone Therapy
Description: Ozone (O3) is a molecule consisting of 3 atoms of oxygen in a dynamically unstable structure. O3 has the capacity to modulate inflammation. O3 when in contact with human fluids and tissues rapidly reacts, generating many reactive oxygen species, as hydrogen peroxide (H2O2), superoxide ion, and hydroxyl radical (OH-). It is suggested that through moderate oxidative stress generated by these reactive byproducts, O2O3 might produce positive effects in several pathologies, including musculoskeletal affections. Moreover, O2/O3 may directly regulate prostaglandins (PGS) and bradykinin, and suppress several proinflammatory mediators, such as IL-6, IL-8 and TNF-α
Study: NCT04952545

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2050
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2050
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral tablet.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral tablet.
Study: NCT05282524

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transvaginal ultrasound performed by a woman herself (with remote healthcare professional supervision)
Description: Imaging performed by woman on herself with remote healthcare professional (HCP) supervision. The ultrasound device used is cleared for HCP-supervised use in environments where healthcare is provided by trained HCPs. No changes to the design or manufacture have been made for this study.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transvaginal ultrasound performed by a woman herself (with remote healthcare professional supervision)
Description: Imaging performed by woman on herself with remote healthcare professional (HCP) supervision. The ultrasound device used is cleared for HCP-supervised use in environments where healthcare is provided by trained HCPs. No changes to the design or manufacture have been made for this study.