TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05411822

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lighting Intervention Blue light
Description: Custom made lighting fixture that will deliver the blue lighting intervention

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lighting Intervention Green light
Description: Custom made lighting fixture that will deliver the green lighting intervention
Study: NCT05243212

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-BCMA
Description: CAR-BCMA T-cells are genetically modified autologous T-cells directed to the B-cell maturation antigen (BCMA). CAR-BCMA T-cells identify and eliminate BCMA-expressing malignant plasma cells. Upon binding to BCMA-expressing cells, the CAR transmits a signal to promote T cell expansion, activation, persistence and elimination of malignant plasma cells.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-BCMA
Description: CAR-BCMA T-cells are genetically modified autologous T-cells directed to the B-cell maturation antigen (BCMA). CAR-BCMA T-cells identify and eliminate BCMA-expressing malignant plasma cells. Upon binding to BCMA-expressing cells, the CAR transmits a signal to promote T cell expansion, activation, persistence and elimination of malignant plasma cells.
Study: NCT04230148

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Egaten (Triclabendazole) 250 mg tablets
Description: Egaten 250 mg scored tablets for oral use.
Study: NCT05412927

Intervention type: DEVICE
Intervention: PMA P150009 AngelMed Guardian® System
Description: The AngelMed Guardian® System is an implantable cardiac monitor with patient alerting capability and an additional external alarm device. The Guardian® System is indicated for use in patients who have had prior ACS events and who remain at high risk for recurrent ACS events. The Guardian® System is indicated as an adjunct to patient recognized symptoms. The Guardian® System detects potential ongoing ACS events, characterized by sustained ST segment changes, and alerts the patient to seek medical attention for those potential ACS events.~A Guardian® System alert is a more accurate predictor of ACS events when compared to patient recognized symptoms alone and demonstrates a reduced rate over time of patient presentations without ACS events (false positives) when compared to patient recognized symptoms alone. In the absence of symptoms, the Guardian® System may identify asymptomatic ACS events and prompt the patient to seek medical attention.
Study: NCT05052190

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Portal Message R/R with Direct Appointment Schedule Link
Description: Participants in this arm will receive up to 3 R/R messages by portal. R/R message will be sent with a Direct Appointment Scheduling link and instructions to make a flu vaccine appointment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Portal Message R/R with Direct Appointment Schedule Link
Description: Participants in this arm will receive up to 3 R/R messages by portal. R/R message will be sent with a Direct Appointment Scheduling link and instructions to make a flu vaccine appointment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Portal Message R/R without Direct Appointment Schedule Link
Description: Participants in this arm will receive up to 3 R/R messages by portal. R/R message will be sent without a Direct Appointment Scheduling link and instructions to make a flu vaccine appointment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Portal Message R/R without Direct Appointment Schedule Link
Description: Participants in this arm will receive up to 3 R/R messages by portal. R/R message will be sent without a Direct Appointment Scheduling link and instructions to make a flu vaccine appointment.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Portal Pre-Appointment Reminder
Description: Participants will receive a Pre-Appointment Reminder via the portal advising them to ask their doctor for the flu vaccine at their upcoming appointment via text when they schedule a visit during the study period.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Portal Pre-Appointment Reminder
Description: Participants will receive a Pre-Appointment Reminder via the portal advising them to ask their doctor for the flu vaccine at their upcoming appointment via text when they schedule a visit during the study period.
Study: NCT04440748

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: T-Chair 2.0 Prototype
Description: Participants in the experimental group will perform additional therapy with the T-Chair 2.0. Participants can train in two modes. Participants will either train in the active modus, whereby the participant has to move the seat in a certain direction, or in the passive modus, whereby the participant has to stay in a stable position while the seat is moving underneath the participant. The seat is able to move in mediolateral, anteroposterior, and diagonal and combined directions such as circles or eight-figures. The modus, the type of movement, the range of motion and speed of movement are chosen by the therapist according to the patients' abilities.Training will be coupled with a computer based exercise. During the session preparation time, and time for the questionnaires is needed, thus we expect the actual training time to be on average 30 minutes per training.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: General Rehabilitation Programme
Description: The general rehabilitation program that is offered to all patients of Clinic Valens fits the current standards for treatment post-stroke. This program is tailored to the patients needs and consists of a 90 minute so called focus training per day, which includes physical therapy, occupational therapy, resistance training and gait training. According to the patient needs, extra therapy will be given such as robotic therapy, speech therapy and aquatic therapy. The general rehabilitation program in both groups is comparable in content, time and intensity.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: General Rehabilitation Programme
Description: The general rehabilitation program that is offered to all patients of Clinic Valens fits the current standards for treatment post-stroke. This program is tailored to the patients needs and consists of a 90 minute so called focus training per day, which includes physical therapy, occupational therapy, resistance training and gait training. According to the patient needs, extra therapy will be given such as robotic therapy, speech therapy and aquatic therapy. The general rehabilitation program in both groups is comparable in content, time and intensity.
Study: NCT05523817

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a form of non-invasive brain stimulation used to treat depression. It works on the principles of electromagnetic induction.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a form of non-invasive brain stimulation used to treat depression. It works on the principles of electromagnetic induction.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a form of non-invasive brain stimulation used to treat depression. It works on the principles of electromagnetic induction.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a form of non-invasive brain stimulation used to treat depression. It works on the principles of electromagnetic induction.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a form of non-invasive brain stimulation used to treat depression. It works on the principles of electromagnetic induction.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a form of non-invasive brain stimulation used to treat depression. It works on the principles of electromagnetic induction.
Study: NCT06388889

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexpramipexole Dihydrochloride
Description: Oral administration of dexpramipexole tablet
Study: NCT05888493

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tisagenlecleucel
Description: Tisagenlecleucel is a solution for infusion of 0.6 to 6 x 10\^8 CAR-positive viable T-cells taken intravenously (i.v.).

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lenalidomide and rituximab (R2) in 28-day cycles for up to 12 cycles.
Description: Lenalidomide 20 mg daily on days 1-21 for up to 12 cycles Rituximab 375 mg/m2 IV on days 1, 8, 15, and 22 of cycle 1 and day 1 of cycles 2-5

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone or prednisolone (R-CHOP) in 21-day cycles for 6 to 8 cycles
Description: Rituximab 375 mg/m2 i.v. on day 1 Cyclophosphamide 750 mg/m2 i.v. day 1 Doxorubicin 50 mg/m2 i.v. day 1 Vincristine 1.4 mg/2 (capped at 2 mg) i.v. day 1 Prednisone or prednisolone 40 mg/m2 PO days 1-5

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lymphodepleting chemotherapy
Description: Fludarabine (25 mg/m\^2 intravenously \[i.v.\] daily for 3 doses) OR Cyclophosphamide (250 mg/m\^2 i.v. daily for 3 doses starting with the first dose of fludarabine).~OR Bendamustine 90 mg/m\^2 i.v. daily for 2 days (If there was previous grade IV hemorrhagic cystitis with cyclophosphamide, or the participant demonstrated resistance to a previous cyclophosphamide-containing regimen)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Corticosteroids and/or Radiation (Bridging therapy)
Description: Corticosteroids and/or Radiation
Study: NCT05693272

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVAC-1
Description: Intramuscular vaccine against SARS-CoV-2

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVAC-1
Description: Intramuscular vaccine against SARS-CoV-2

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: COVAC-1
Description: Intramuscular vaccine against SARS-CoV-2

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Saline Placebo
Description: Intramuscular injection of saline placebo
Study: NCT06087159

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mHealth Toolkit for Wellness & Empowering Lives of School Community (mWEL)
Description: mWEL-App is a preventive intervention tool for teachers and parents as a self-help support. It integrates three key mental health presentive service functions: i) comprehensive screen to assess mental health (anxiety, depression), stress, and related contextual risks; ii) a tailored strength and weakness profile/report with recommendations to promote self-awareness and mental health knowledge; and iii) tailored evidence-based strategies and additional support and clinical resources to improve skills in stress management, emotion regulation, and maintain mental wellness. mWEL will be designed as a self-administered tool. Participating parents and teachers can access to mWEL app after they sign up for an account. Intervention participants will have access to the App anytime within a 3-5 month study period.
Study: NCT06336642

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SPOT-ON Early Start
Description: Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and/or trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SPOT-ON Early Start
Description: Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and/or trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SPOT-ON Delayed Start
Description: Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and/or trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SPOT-ON Delayed Start
Description: Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and/or trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.
Study: NCT05233904

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Diagnostic-CT-enabled Planning
Description: Diagnostic-CT-enabled planning for patient receiving palliative radiation treatment to bone, soft tissue and lung disease

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Patients will be booked for CT simulation and treatment as per the local institution's standard practice
Study: NCT04785261

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylhydroxypropylcellulose
Description: 1-2 drips each time, every 4 hours, for 12 weeks.
Study: NCT05685342

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetaminophen/Ibuprofen fixed-dose combination
Description: Intravenous administration of Acetaminophen (1000 mg)/Ibuprofen (300 mg) fixed-dose combination (total 100 ml)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen/Ibuprofen fixed-dose combination
Description: Intravenous administration of Acetaminophen (1000 mg)/Ibuprofen (300 mg) fixed-dose combination (total 100 ml)
Study: NCT04785261

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylhydroxypropylcellulose
Description: 1-2 drips each time, every 4 hours, for 12 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carbomer
Description: 1 drip each time, at bedtime, for 12 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbomer
Description: 1 drip each time, at bedtime, for 12 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCM Formula
Description: 6.0g Chi-Ju-Di-Huang-Wan plus 6.0g Jia-Wei-Xiao-Yao-San, 6.0g twice daily for 12 weeks.
Study: NCT06570993

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cool roof
Description: Cool roofs are a heat-reflecting material that can be applied to existing household roofing in the form of a liquid-applied membrane. Cool roofs work by increasing solar reflectance (the ability to reflect the visible wavelengths of sunlight, reducing heat transfer to the surface) and thermal emittance (the ability to radiate absorbed solar energy) thereby reducing the amount of heat transferred into the home.
Study: NCT05893017

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Exercises
Description: Virtual Reality Exercises will be apply for muscle strengthening

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Exercises and Kinesiotaping
Description: Virtual Reality Exercises will be apply for muscle strengthening, Kinesiotaping will be applied at Quadriceps muscle and Hamstring muscle

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Exercises and Valgus Orthoses
Description: Virtual Reality Exercises will be apply for muscle strengthening, Orthoses is for correction at knee alignment
Study: NCT05491837

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Device induce acute intermittent hypoxia 9 % of Oxygen
Description: Interventional group will be provided a brief sequence of mild hypoxia consisting of 9% oxygen for one minute followed by normoxia 21% of oxygen for a total of 15 episodes

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Normoxia 21% of oxygen
Description: SHAM group will be provided normoxia 21% of Oxygen
Study: NCT05643807

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Flexible cystoscopy
Description: Urinary cytology will be collected through the flexible cystoscope itself at the end the cystoscopy. Before starting the urinary collection, the cystoscope will either be placed in front of a suspected intravesical lesion (if present) or at the bladder neck (if no lesion present).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Urinary catheter
Description: Urinary cytology will be collected through a Ch14 urinary catheter after the cystoscopy
Study: NCT05491837

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normoxia 21% of oxygen
Description: SHAM group will be provided normoxia 21% of Oxygen
Study: NCT05696457

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Passive music therapy
Description: Patients included in the experimental group receive a 25 min passive music therapy session on a daily basis, which changes depending on their emotion.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Passive music therapy
Description: Patients included in the experimental group receive a 25 min passive music therapy session on a daily basis, which changes depending on their emotion.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Passive music therapy
Description: Patients included in the experimental group receive a 25 min passive music therapy session on a daily basis, which changes depending on their emotion.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Passive music therapy
Description: Patients included in the experimental group receive a 25 min passive music therapy session on a daily basis, which changes depending on their emotion.
Study: NCT05952154

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transapical beating-heart septal myectomy
Description: We have invented a beating-heart myectomy device.Through a minimally invasive intercostal incision, septal myectomy could be accomplished via a transapical access in the beating heart using the device. The whole process of resection is monitored, navigated, and evaluated by real-time transesophageal and transthoracic echocardiography. Left ventricular end-diastolic volume and the grade of mitral regurgitation are evaluated each time after resection. Multiple resections are performed to tailor the muscular resection for sufficient enlargement of left ventricular end-diastolic volume and improvement of mitral regurgitation, while preventing iatrogenic injuries.
Study: NCT05375448

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neural mobilisation
Description: Participants will perform an active femoral nerve mobilisation technique. The treatment will be performed at home.~Patients will receive a video model to perform the exercise during the 8 weeks of treatment. The treatment should be performed 10 repetitions twice a day, with one set recommended in the morning and one in the evening.~The treatment will be monitored by telephone and if there are any doubts, the session will be carried out together with the patient.
Study: NCT06281535

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Implant loading
Description: Placement of abutments and final restorations either 2 months following implant placement in early loading group or 3 months in conventional loading group

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Implant loading
Description: Placement of abutments and final restorations either 2 months following implant placement in early loading group or 3 months in conventional loading group
Study: NCT05142605

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meaning-Centered Grief Therapy
Description: Meaning-Centered Grief Therapy is a therapy that focuses on helping participants find a sense of meaning or purpose in participants' life after participants' loss. Parents will be provided (via mail or email) a workbook. This support program will involve 16 sessions that will take place about once a week. Each session will last 60 to 90 minutes and will be delivered through videoconferencing.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Supportive Psychotherapy
Description: Supportive Psychotherapy will help participants cope with participants' loss by giving them a place to express participants' feelings and providing participants with support during the sessions. Supportive counseling will involve 16 sessions that will take place about once a week. Each session will last 60 to 90 minutes and will be delivered through videoconferencing.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: Enhanced usual care includes any support or resources participants may receive as part of participants' standard care (for example, therapy sessions with a local therapist), enhanced with additional resources.
Study: NCT06039709

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: 5-ALA and Low-Intensity Focused Ultrasound (SDT)
Description: 5-ALA (20mg/kg orally) given \~6 hours prior to LIFU. Focused ultrasound will target a maximum of 50% of the tumor.
Study: NCT05509803

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PE Audit and Feedback Tool
Description: The intervention consists of a Physical Education (PE) Audit and Feedback tool, which was adapted from work done through the PE Works program in the New York City Department of Education. A district-level PE program leader in Oakland Unified School District will deliver the tool, which consists of auditing the current status of PE in intervention schools, providing feedback on the status to help improve PE, and providing technical assistance to bring schools up to code and ensure support for PE programming.
Study: NCT05663203

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet-Based Intervention
Description: Attend CRCWeb intervention

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Complete interview

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Complete survey

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Medical records are reviewed
Study: NCT04999020

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ravulizumab
Description: Intravenous dosing will consist of a loading dose followed by maintenance doses administered every 8 weeks (q8w). The maintenance dosing will be initiated 2 weeks after the loading dose is administered.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intravenous dosing will consist of a loading dose followed by maintenance doses administered q8w. The maintenance dosing will be initiated 2 weeks after the loading dose is administered.
Study: NCT06129422

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NMK89
Description: Route of administration: intravenous infusion