TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05094713

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Flossing experimental group
Description: Flossing of the tight muscles with medium wrapping pressure, which is individualized in based on the tight circumference of the participant.

Intervention type: OTHER
Group type: OTHER
Intervention: Low wrapping pressure
Description: Control group where flossing wrapping pressure is between 20 and 30 mmHg
Study: NCT05717036

Intervention type: DEVICE
Intervention: Serum Total Protein Measurement with TS Meter-DSP and Refractix DSP
Description: The two blood samples will be centrifuged and hematocrit measured per the plasma center's standard operating procedures. One participant sample will be dispensed onto the cleared TS Meter-DSP for a serum total protein measurement. This measurement will be used, along with other pre-screening information, to determine if the participant can donate plasma. The second participant sample will be dispensed onto the investigational Refractix DSP for a serum total protein measurement. It will be compared to the sample measurement taken on the cleared TS Meter-DSP.
Study: NCT06679816

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hormone replacement therapy
Description: Perioperative Hydrocortisone Reduction Therapy

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Perioperative placebo Reduction Therapy
Study: NCT04810416

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Texting- 10 minutes
Description: Participants will practice texting for 10 minutes using smart phone.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Writing- 10 minutes
Description: Participants will practice writing on notebook for 10 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Texting- 15 minutes
Description: Participants will practice texting for 15 minutes using smart phone.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Writing- 15 minutes
Description: Participants will practice writing on notebook for 15 minutes.
Study: NCT03996109

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aim2Be smartphone app system
Description: Youth-parent dyads will receive the LiGHT program (addressing healthy eating, physical activity, screen time and sleep) via the Aim2Be smartphone app for 6 months. It provides personalization beginning with creation of an avatar and identifying user motivations, offers progressive goal-setting considering readiness, sub-tasks, milestones, self-monitoring tools with feedback and positive reinforcement. It applies behaviour change techniques, provides a knowledge centre, simulation narratives to enable decision making, and separate social exchange platforms for parents and youth to share ideas and challenges with peers. A Virtual Coach has been programmed using motivational interviewing theory. Gamification includes elements of choice, challenge, uncertainty, discovery, and kudos for achieving outcomes in the process of developing motivations, skills and mastery.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: BnLt smartphone app
Description: Youth-parent dyads will receive a simple app called BnLt for 6 months. It provides web-links to external websites that provide information and tips on healthy eating and activity, including the Canada Food Guide, Canadian Society of Exercise Physiology recommendations for physical activity, screen time and sleep for youth, and other resources.
Study: NCT05214768

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CC-93538
Description: Specified dose on specified days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Specified dose on specified days
Study: NCT04662996

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: one blood sample is done before beginning a first treatment line for a metastatic castration resistant prostate cancer

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: one blood sample is done before beginning a first treatment line for a metastatic castration resistant prostate cancer
Study: NCT06225232

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin combined with Psychotherapy
Description: The intervention consists of a 9-week treatment protocol that is based on supportive psychotherapy and Motivational Enhancement Therapy. Overall, the therapy course includes 8 motivational enhancement therapy sessions and two experimental drug sessions.
Study: NCT05799781

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MPC closed-loop system
Description: The Model Predictive Control (MPC) insulin infusion algorithm contains a model within the controller that takes as an input the aerobic metabolic expenditure in addition to the CGM and meal in puts. The algorithm uses heart rate and accelerometer data collected on the patient's body to calculate metabolic expenditure (METs). The METs then acts on the model for the insulin dynamics, whereby more energy expenditure and longer duration exercise can lead to a more substantial effect of insulin on the CGM. The MPC also has missed meal insulin bolus detection where the system will calculate the amount of insulin that was missed for a meal. The missed meal boluses can be delivered automatically without any input from the user. This feature can also be disabled.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: t:slim X2 pump with Dexcom G6 CGM and Control IQ
Description: The t:slim pump is a hybrid closed-loop system available to consumers for automated insulin delivery. Control IQ technology automatically adjusts insulin levels based on continuous glucose monitoring (CGM) readings from Dexcom G6.
Study: NCT06423066

Intervention type: DIAGNOSTIC_TEST
Intervention: Pleural ultrasound
Description: Patients who examine pleural ultrasound preoperatively.
Study: NCT05898919

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture is a technique that inserts a needle into the acupuncture point to treat a condition. In this trial, we will use acupuncture to treat postoperative urinary retention.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham acupuncture
Description: Participants will receive sham acupuncture at sham points.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neostigmine Injectable Product
Description: Neostigmine was injected once after postoperative urinary retention.
Study: NCT05097326

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mifepristone
Description: Mifepristone 200mg taken orally

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Misoprostol
Description: Misoprostol 50 mcg taken orally, and may receive additional doses of misoprostol 50 - 100 mcg as needed
Study: NCT04364568

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: IRM Sequences T1, T2, FLAIR, T2\*, Cerebral Blood Flow (CBF) et mean diffusivity (MD)

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: IRM Sequences T1, T2, FLAIR, T2\*, Cerebral Blood Flow (CBF) et mean diffusivity (MD)
Study: NCT06311942

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HAIC plus PD-1 inhibitors plus lenvatinib
Description: Patients in the triple adjuvant therapy group received one cycle of HAIC about a month after liver resection, HAIC was adopted the FOFOLX6 program (Folinic acid+5-fluorouracil+Oxaliplatin). The first cycle of PD-1 monoclonal antibody was administrated 2-4 weeks postoperatively, 200 mg IV, every 21 days for a total of 9 cycles. Lenvatinib was initiated orally 2-4 weeks postoperatively for 6 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PD-1 inhibitors plus lenvatinib
Description: The first cycle of PD-1 monoclonal antibody was administrated 2-4 weeks postoperatively, 200 mg IV, every 21 days for a total of 9 cycles. Lenvatinib was initiated orally 2-4 weeks postoperatively for 6 months.
Study: NCT05226169

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ferinject
Description: * Patients will receive an IV FCM (1,000 mg iron) infusion on the first day (visit 1) of chemotherapy. FCM (FerinjectTM; Vifor Pharma, Glattbrugg, Switzerland) will be diluted in 250 ml of sterile 0.9% normal saline by an aseptic technique and infused over 15 min under the supervision of a clinician.~* Patients with a Hb level ≤ 10 g/dL and ID (serum ferritin \< 100 ng/mL or TSAT \< 50% and serum ferritin 100-500 ng/mL) will receive an additional dose of 500 mg of IV FCM at 6, 12, 24, 36, and 48 weeks. FCM will be diluted in 100 ml of sterile 0.9% normal saline by an aseptic technique and infused over 6 min under the supervision of a clinician.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative management
Description: * Patients with absolute (must be administered) or functional (according to the physician's choice) IDA in the control arm will be received oral iron, administered as Feroba-You 256mg once or twice a day. Advice will be given regarding ingestion without food and with liquid high in ascorbic acid to maximize enteric absorption.~* If patients in the control arm still meet the absolute or functional IDA at the end of study (at 48 weeks), they can receive IV FCM (1,000 mg) according to the physician's decision.
Study: NCT04980001

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Families OverComing Under Stress Trauma Informed Care in Childhood Obesity among Minorities (FOCUS TIC-COM)
Description: FOCUS TIC-COM is a program that helps doctors coach families to recognize how emotions or feelings about various life stressors may affect a child's dietary choices and physical activity. FOCUS TIC-COM is for families of children who have been identified by their doctor as overweight or obese. The goal of the program is to help children and their families understand how their mental health may impact their physical health and develop strategies to address their mental health needs.
Study: NCT04840797

Intervention type: DEVICE
Intervention: HeartStart HS1
Description: Automated External Defibrillator
Study: NCT06143722

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: simultaneous with radiotherapy
Description: Chemotherapy combined with immunotherapy simultaneous with radiotherapy

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: synchronous with radiotherapy
Description: Chemotherapy combined with immunotherapy synchronous with radiotherapy
Study: NCT06219473

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fascia lata membrane
Description: novel allogenic derived acellular matrix produced from human fascia lata allograft

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Platlet Rich fibrin membrane
Description: Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRF where autologous platelets and leukocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: subepithelial connective tissue graft
Description: The connective tissue is generally taken from the hard palate, although it may be taken from other sites as well, such as the maxillary tuberosity area.
Study: NCT05791032

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AtaCor EV-ICD Lead
Description: Subjects will receive the AtaCor EV-ICD Lead being evaluated in the study.
Study: NCT03348670

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abiraterone - Usual
Description: * Oral~* Abiraterone Combined Chemotherapy (high dose)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abiraterone - Study
Description: * Oral~* Abiraterone Combined Chemotherapy (low dose)
Study: NCT05702567

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RF + PFMT
Description: During each session the patient is lying face up, with knees bent and feet resting on the stretcher.~Then, the vaginal probe is introduced into the cavity using a lubricant suitable for intracavitary use and radiofrequency. The device is started at 15% intensity and adapting to a 10-point Likert scale, at point 3 or 4 of intensity.~At the same time that the radiofrequency is applied, pelvic floor contractions are performed guided by the physiotherapist, and these contractions are three:~* 10 fast contractions of one second each, with 10 seconds of rest.~* 5 seconds of sustained contraction and 10 seconds of rest.~* 10 seconds of contraction maintained with 10 seconds of rest.~The contraction maintenance time will be adapted to what each woman can keep the pelvic floor contracted, with a view to the goal being to complete these exercises cyclically during the entire session.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: PFMT + Placebo RF
Description: The intervention is exactly the same as the group RF + PFMT, unlike the non-functioning of the RF in the patients belonging to this group.~The patient is lying face up, with knees bent and feet resting on the stretcher. Then, the vaginal probe is introduced into the cavity using a lubricant suitable for intracavitary use and radiofrequency, the device is started at 15% intensity, but in this case, the program does not work or apply radiofrequency to the patients.~At the same time, that the radiofrequency's probe is applied, pelvic floor contractions are performed guided by the physiotherapist, and these contractions are the three named in the Radiofrequency + PFMT.~The contraction maintenance time will be adapted to what each woman can keep the pelvic floor contracted, with a view to the goal being to complete these exercises cyclically during the entire session.
Study: NCT05564247

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wheelchair Skills Training Program (WSTP)
Description: Participants will complete customized MWC skills training based on the evidence-based wheelchair skills program. Lessons plans will be created by the clinicians, children and parents participants based on goals, age, skills and interests, and used to customize the training.
Study: NCT06677970

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BP lowering drugs (nicardipine, labetalol, urapidil)
Description: After successful reperfusion, appropriate antihypertension medication is administered to control systolic blood pressure \<180 mmHg.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BP raising drug (phenylephrine) or BP lowering drugs (nicardipine, labetalol, urapidil)
Description: After successful reperfusion, appropriate BP raising (20% increase in SBP, maximum of 180 from baseline SBP) are administered.
Study: NCT05539222

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Food vouchers and education
Description: Intervention and control group individuals received 120 euros/month during 3 months in food vouchers to be spent in supermarkets (60 euros/month if under 12y) plus a 10-week nutrition education for the intervention group. Family food purchases were assessed using electronically recorded supermarket-obtained transactions.
Study: NCT04849520

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High flow nasal cannula
Description: Oxygen supplement via high flow nasal cannula at a rate of 2 liters/kg/min

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Buccal oxygenation
Description: Oxygen supplement intra-orally via oral Ring-Adair-Elwyn endotracheal tube connected to oxygen at a rate of 0.5 liters/kg/min
Study: NCT06282705

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diagonal Drop Jumps 0cm
Description: Participants will complete 4 unsupervised home drop jump sessions per week ( minimum 24 hours between each session) for the duration of the study (e.g., Mon, Wed, Fri, Sun) from a height of 0 cm (floor). They will perform 20 diagonal drop jumps on each side (20 x dropping left and 20 x dropping right) with 30 seconds between each jump. The routine will be demonstrated in full on the first laboratory session. The intervention will last 16 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diagonal Drop Jumps 40cm
Description: Participants will complete 4 unsupervised home drop jump sessions per week ( minimum 24 hours between each session) for the duration of the study (e.g., Mon, Wed, Fri, Sun) from a height of 40 cm (plyo box). They will perform 20 diagonal drop jumps on each side (20 x dropping left and 20 x dropping right) with 30 seconds between each jump. The routine will be demonstrated in full on the first laboratory session. The intervention will last 16 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diagonal Drop Jumps 60cm
Description: Participants will complete 4 unsupervised home drop jump sessions per week ( minimum 24 hours between each session) for the duration of the study (e.g., Mon, Wed, Fri, Sun) from a height of 60 cm (plyo box). They will perform 20 diagonal drop jumps on each side (20 x dropping left and 20 x dropping right) with 30 seconds between each jump. The routine will be demonstrated in full on the first laboratory session. The intervention will last 16 weeks.
Study: NCT04922112

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Obstructive sleep apnea testing
Description: * Functional Outcomes of Sleep Questionnaire (FOSQ-10)~* European Organization for Research and Treatment of Cancer Head and Neck Survey (EORTC HN 35)~* Epworth Sleepiness Scale (ESS)~* Adult Comorbidity Evaluation (ACE 27)~* University of Washington Quality of Life Questionnaire (UW-QOL)~* Chronic Pain Assessment Questionnaire
Study: NCT05065229

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oxygen saturation probe Mindray 520 N and Mindray 521 N
Description: Two oxygen saturation probes will be used in this study:~Mindray 520 N is a disposable oxygen saturation sensor for neonates and adults. It is a disposable, single-use sensor that is wrapped around the infant's arm or foot. Its ends stick together giving a firm, close contact with the skin.~Mindray 521 N is another disposable oxygen saturation sensor for neonates and adults that is used on the neonatal unit in routine practice. As Mindray 520 N and 521 N are CE marked and used within their intended purposes we do not require a letter of no objection from the MHRA for that usage. The Mindray probes will be used without modification and there are no safety issues to the patient. Therefore, a letter of no objection from the MHRA is not required and this is not a medical device study under the Medical Devices Directive.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oxygen saturation probe Mindray 520 N and Mindray 521 N
Description: Two oxygen saturation probes will be used in this study:~Mindray 520 N is a disposable oxygen saturation sensor for neonates and adults. It is a disposable, single-use sensor that is wrapped around the infant's arm or foot. Its ends stick together giving a firm, close contact with the skin.~Mindray 521 N is another disposable oxygen saturation sensor for neonates and adults that is used on the neonatal unit in routine practice. As Mindray 520 N and 521 N are CE marked and used within their intended purposes we do not require a letter of no objection from the MHRA for that usage. The Mindray probes will be used without modification and there are no safety issues to the patient. Therefore, a letter of no objection from the MHRA is not required and this is not a medical device study under the Medical Devices Directive.
Study: NCT06125483

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Umbilical Cord Blood Transplantation
Description: Compared with peripheral blood stem cell transplantation (PBST), UCBT has a higher transplantation rate, as cord blood stem cells are more primitive. Since the first successful umbilical cord blood transplantation (UCBT) in a child with severe Fanconi anemia reported by Gluckman et al. in France in 1988, cord blood has been widely used as a graft source of hematopoietic stem cells for the treatment of hematological diseases. The first sibling UCBT for leukemia was performed successfully by Professor Yongping Song in China, who played a pioneering role in the development of UCBT for leukemia in China. On the basis of previous research, TBI/Flu/Bu/Mel combined with UCBT is safe and feasible for the treatment of patients with malignant hematological diseases who experienced post-transplant relapse, which has enormous potential to improve patient outcomes.
Study: NCT05619783

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AMX0035
Description: Combination of 3 g phenylbutyrate and 1 g taurursodiol
Study: NCT05815056

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sedakit (R) using hypnosis induced by the virtual reality device
Description: we use the virtual reality device and no medication during the surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: drug intervention
Description: using sufentanyl 5mg intravenously during the surgery
Study: NCT06370221

Intervention type: BEHAVIORAL
Intervention: The effect of psoriatic Arthritis
Description: to assess the frequency rates of sexual problems and associated factors in a cohort of married females with Psoriatic arthritis, and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients.

Intervention type: BEHAVIORAL
Intervention: The effect of psoriatic Arthritis
Description: to assess the frequency rates of sexual problems and associated factors in a cohort of married females with Psoriatic arthritis, and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients.
Study: NCT06755736

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: superficial cervical plexus block
Description: In anterior cervical discectomy surgeries, superficial cervical block will be used for analgesia.
Study: NCT06766409

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A community group-based demonstration counseling method
Description: At the community level, a perinatal woman in the intervention arm will get individual family planning counseling along with group-based counseling that includes a planned demonstration of all possible techniques.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: An individual family planning counseling
Description: The control group's pregnant and postpartum women will simply get standard individual FP counseling in accordance with Ethiopian national recommendations.
Study: NCT06750224

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alexander technique
Description: 24 sessions for 8 weeks, per week 3 sessions will be given

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Feldenkrais method
Description: The method is divided into eight lessons according to 'Awareness Through Movement'. Each lesson will be given three times for one week.