TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05014334

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berberine
Description: berberine 500 mg, twice daily for 14 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: Vonoprazan 20 mg, twice daily for 14 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vonoprazan
Description: Vonoprazan 20 mg, twice daily for 14 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin
Description: amoxicillin 1000mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: amoxicillin 1000mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: amoxicillin 1000mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rabeprazole
Description: Rabeprazole 10mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bismuth
Description: Bismuth 220mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bismuth
Description: Bismuth 220mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clarithromycin
Description: clarithromy 500mg, twice daily for 14 days.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clarithromycin
Description: clarithromy 500mg, twice daily for 14 days.
Study: NCT06417112

Intervention type: DIAGNOSTIC_TEST
Intervention: Transthoracic Echocardiogram
Description: All participants have been referred for a transthoracic echocardiogram by a clinician.

Intervention type: DIAGNOSTIC_TEST
Intervention: Transthoracic Echocardiogram
Description: All participants have been referred for a transthoracic echocardiogram by a clinician.

Intervention type: DIAGNOSTIC_TEST
Intervention: Transthoracic Echocardiogram
Description: All participants have been referred for a transthoracic echocardiogram by a clinician.
Study: NCT05798130

Intervention type: OTHER
Intervention: No intervention group.
Description: No intervention group.

Intervention type: OTHER
Intervention: No intervention group.
Description: No intervention group.
Study: NCT05159154

Intervention type: DEVICE
Intervention: Myocardial Work
Description: Myocardial work (MW) is emerging as an alternative tool for studying LV myocardial systolic function, because it incorporates both deformation and load into its analysis. In this context, MW could be considered as an advancement of myocardial strain, allowing to investigate LV performance also in cases of changes in afterload that could lead to misleading conclusions if relying only on strain analysis. This parameter will be evaluated by using an echographer equipped with a specific software for the analysis (Ecog Vivid E95 Ultra GE®)
Study: NCT05383404

Intervention type: DIAGNOSTIC_TEST
Intervention: blood and urine samples
Description: complete blood count, blood glucose, blood gases, serum bicarbonates, serum electrolytes, serum albumin ,serum creatinine. blood urea nitrogen, urine analysis.

Intervention type: DIAGNOSTIC_TEST
Intervention: blood and urine samples
Description: complete blood count, blood glucose, blood gases, serum bicarbonates, serum electrolytes, serum albumin ,serum creatinine. blood urea nitrogen, urine analysis.

Intervention type: DIAGNOSTIC_TEST
Intervention: blood and urine samples
Description: complete blood count, blood glucose, blood gases, serum bicarbonates, serum electrolytes, serum albumin ,serum creatinine. blood urea nitrogen, urine analysis.
Study: NCT06036251

Intervention type: OTHER
Intervention: Questionnaires
Description: Self-reported quality of life (QOL) measures completed online
Study: NCT05693168

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ANNE Limb Sensor
Description: Pulse Oximeter
Study: NCT02126033

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: take blood samples
Study: NCT05614687

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community-informed art-based programme
Description: The Community-informed art-based programme is an intervention incorporating art in the form of for example poetry and drawings in addressing trauma and encouraging community attitudes towards the positive reintegration of ex-offenders.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Government Media Intervention
Description: Government Media Intervention involving media content from the National Orientation Agency and other media sources
Study: NCT04941066

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active neurofeedback
Description: The session will be done on an individual basis. The active group will receive neurofeedback training from the rumination-related brain functional connectivity.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham neurofeedback
Description: The session will be done on an individual basis. The sham group will receive neurofeedback training from an artificially generated random feedback signal.
Study: NCT06280222

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The VR instrument - Oculus Quest 2
Description: Patients in the interventional group will watch 20-minute scenery movies in the VR instrument before entering the oocyte retrieval procedure.
Study: NCT06429267

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bioabsorbable Screw
Description: Bioabsorbable screw that redissolves into the bone. Mineral fibers are composed of Silicon Dioxide (SiO2), Sodium Oxide, Calcium Oxide, Magnesium Oxide, Boron Trioxide, and Phosphorous Pentoxide

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Metal/Titanium Screw
Description: Traditional metal screw used in fracture fixation that requires hardware removal
Study: NCT05289050

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: sodium chloride (NaCl; 0.9%)
Description: For patients in the control group,anaesthesia will be maintained with intravenous sodium chloride (NaCl; 0.9%) infusion.while anaesthesia will be maintained with propofol infusion(4-12mg/kg/h),analgesia will be maintained with remifentanil(0.15-0.3ug/kg/min).The sufentanil dose at induction and the rate of intraoperative remifentanil and propofol infusions were at the discretion of the anesthesiologist in charge of the patient.The assessment of the depth of anesthesia was based on clinical evaluation,placebo-controlled infusion will be stopped 15 minutes before the end of surgery.Propofol and remifentanil infusion will be stopped at the end of surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-ketamine
Description: For patients in the s-ketamine group,anaesthesia will be maintained with s-ketamine infusion（0.3mg/kg/h),while anaesthesia will be maintained with propofol infusion(4-12mg/kg/h),analgesia will be maintained with remifentanil(0.15-0.3ug/kg/min).The sufentanil dose at induction and the rate of intraoperative remifentanil and propofol infusions were at the discretion of the anesthesiologist in charge of the patient.The assessment of the depth of anesthesia was based on clinical evaluation.S-ketamine infusion will be stopped 15 minutes before the end of surgery.Propofol and remifentanil infusion will be stopped at the end of surgery.
Study: NCT06270342

Intervention type: OTHER
Intervention: dual task assessment
Description: The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks. In the dual-task turning test, in addition to the single-task turning test, they were given a cognitive task, the task of counting the months of the year backwards from December to January. The dual-task turning test was continued by changing hands at the end of each turn until the last disk was turned. Meanwhile, verbal fluency and hand errors made while spinning the disc were recorded.

Intervention type: OTHER
Intervention: dual task assessment
Description: The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks. In the dual-task turning test, in addition to the single-task turning test, they were given a cognitive task, the task of counting the months of the year backwards from December to January. The dual-task turning test was continued by changing hands at the end of each turn until the last disk was turned. Meanwhile, verbal fluency and hand errors made while spinning the disc were recorded.
Study: NCT05484479

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baduanjin training/exercise
Description: For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be trained using sixty-minute Baduanjin training/exercise (5 times weekly)
Study: NCT05104333

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Covid-19 vaccine (0-1-4 schedule)
Description: Subjects receive the booster vaccine 3 months after the second dose.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Covid-19 vaccine (0-1-6 schedule)
Description: Subjects receive the booster vaccine 5 months after the second dose.
Study: NCT05620147

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Root canal instrumentation EdgeFile X7 to size #35/0.06
Description: Instrumentation will be performed using an endodontic motor at a speed of 300 rpm and a torque of 2 Ncm

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Root canal instrumentation EdgeFile X7 to size #45/0.04
Description: Instrumentation will be performed using an endodontic motor at a speed of 300 rpm and a torque of 2 Ncm

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Root canal instrumentation EdgeFile X7 to size #45/0.06
Description: Instrumentation will be performed using an endodontic motor at a speed of 300 rpm and a torque of 2 Ncm

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Root canal instrumentation EdgeFile X7 to size #35/0.04
Description: Instrumentation will be performed using an endodontic motor at a speed of 300 rpm and a torque of 2 Ncm
Study: NCT06087887

Intervention type: OTHER
Intervention: no interventions
Description: no interventions
Study: NCT05197348

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Meaning-Centered Group Psychotherapy (MCP).
Description: The MCP program is divided into eight sessions:~Session1: Psychoeducation about Meaning in life, Sources of Meaning, etc. Session 2: Cancer illness and meaning. Session 3: Historical Sources of Meaning (the past) Session 4: Historical Sources of Meaning (present and future). Session 5: Attitudinal Sources of Meaning. Session 6: Creative Sources of Meaning. Session 7: Experimental Sources of Meaning. Session 8: End of psychotherapy, farewell, and facing the future with hope.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Psychotherapy (CBT).
Description: The CBT divided into eight sessions:~Session1: Presentation of psychotherapy, establishing the goals of psychotherapy. Presentation of the participants. Updated information about psychological consequences of cancer.~Session 2. Increase in enjoyable activities. Behavioral activation. Progressive muscle relaxation training. Slow breathing training.~Session 3. Cognitive model of coping with cancer. Psychoeducation on negative thoughts. Training in detecting negative thoughts. Presentation of cognitive distortions Session 4. Training in cognitive restructuring techniques. Session 5. Training in problem-solving skills. Session 6. Being aware of participants needs. Self-care. Assertiveness skills training.~Session 7. Setting goals for the future. Session 8. Summary, relapse prevention, and end of psychotherapy.
Study: NCT05082376

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CLM Original
Description: Sunscreen lip balm.
Study: NCT05602662

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Music
Description: Music therapy during mechanical ventilation

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music
Description: Music therapy during mechanical ventilation
Study: NCT04722770

Intervention type: DEVICE
Intervention: PhotoniCare OtoSight Middle Ear Scope
Description: PhotoniCare OtoSight imaging using a near-infrared laser
Study: NCT06346184

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HCP2303
Description: Take 1 tablet once per period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HCP2303
Description: Take 1 tablet once per period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RLD2302
Description: Take 1 tablet once per period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RLD2302
Description: Take 1 tablet once per period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RLD2102
Description: Take 1 tablet once per period

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RLD2102
Description: Take 1 tablet once per period
Study: NCT06149156

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Minds Program App
Description: The four-week intervention comprises two introductory lessons and guided meditations followed by one week of content for each pillar of well-being. Each week includes two brief lessons (5-7 minutes) with education on the scientific research behind the practices, as well as examples of how to strengthen the skills of each pillar in daily life, along with three guided meditations for which the participant can select the practice length (5-30 minutes).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Well-being Resources
Description: List of well-being resources that comprises of online video links and books
Study: NCT06287814

Intervention type: BIOLOGICAL
Intervention: Blood sample/lliquid biopsy
Description: ctDNA analysis
Study: NCT05740020

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality glasses
Description: A specialized VR glasses will be used and VR games application in spider cage

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The traditional exercise program
Description: The selected physical therapy program:~1. Neurodevelopmental approach: aims to facilitate typical motor development and function and to prevent secondary impairments (figure 4).~2. Approximation: aims to control spasticity and stimulate the joint mechanoreceptors (figure 5).~3. Stretching exercise: aims to maintain length and flexibility of shorten muscles (figure 6).~4. Strengthening exercise: aims to improve the functional ability (figure 7).~5. Spider suspension exercise for 30 minutes (figure 8).~5. Gait training activities: aims to improve balance (figure 9). 6. Balance training program: aims to improve balance (figure 10).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The traditional exercise program
Description: The selected physical therapy program:~1. Neurodevelopmental approach: aims to facilitate typical motor development and function and to prevent secondary impairments (figure 4).~2. Approximation: aims to control spasticity and stimulate the joint mechanoreceptors (figure 5).~3. Stretching exercise: aims to maintain length and flexibility of shorten muscles (figure 6).~4. Strengthening exercise: aims to improve the functional ability (figure 7).~5. Spider suspension exercise for 30 minutes (figure 8).~5. Gait training activities: aims to improve balance (figure 9). 6. Balance training program: aims to improve balance (figure 10).
Study: NCT04754282

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Position of labouring women for epidural analgesia catheter placement : Traditional Sitting Position (TSP)
Description: Labouring women admitted to the delivery room of Necker Enfants Malades hospital, requesting an epidural analgesia for labour, and willing to participate in our study will be randomized in the Traditional Sitting Position (TSP) group on odd days or in the Cross-legged Sitting Position (CSP) group on even days.~Patients in the TSP group seat on the edge of the bed, their feet laid on a support set next to the bed. Patients in the CSP group also seat on the edge the bed, but in a so-called tailor position, their knees bent, their hips flexed and in abduction, their feet under each contralateral thigh.~The epidural catheter will be placed according to standard local practice in either of the groups.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Position of labouring women for epidural analgesia catheter placement : Cross-legged Sitting Position (CSP)
Description: Labouring women admitted to the delivery room of Necker Enfants Malades hospital, requesting an epidural analgesia for labour, and willing to participate in our study will be randomized in the Traditional Sitting Position (TSP) group on odd days or in the Cross-legged Sitting Position (CSP) group on even days.~Patients in the TSP group seat on the edge of the bed, their feet laid on a support set next to the bed. Patients in the CSP group also seat on the edge the bed, but in a so-called tailor position, their knees bent, their hips flexed and in abduction, their feet under each contralateral thigh.~The epidural catheter will be placed according to standard local practice in either of the groups.
Study: NCT06212635

Intervention type: DIAGNOSTIC_TEST
Intervention: T-TAS
Description: Blood test, laboratory assays

Intervention type: DIAGNOSTIC_TEST
Intervention: T-TAS
Description: Blood test, laboratory assays

Intervention type: DIAGNOSTIC_TEST
Intervention: T-TAS
Description: Blood test, laboratory assays

Intervention type: DIAGNOSTIC_TEST
Intervention: T-TAS
Description: Blood test, laboratory assays
Study: NCT06274008

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Exparel
Description: Admixture bupivacaine 0.5 % 10 cc with Bupivacaine Liposome Injectable Suspension 10cc total 20
Study: NCT05060263

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HOT-1030
Description: HOT-1030 is a Recombinant Humanized CD137 Monoclonal Antibody Injection
Study: NCT05571748

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alpha-lipoic acid
Description: A trial of acute exercise before and after 4 weeks of alpha-lipoic acid supplementation.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alpha-lipoic acid
Description: A trial of acute exercise before and after 4 weeks of alpha-lipoic acid supplementation.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alpha-lipoic acid
Description: A trial of acute exercise before and after 4 weeks of alpha-lipoic acid supplementation.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alpha-lipoic acid
Description: A trial of acute exercise before and after 4 weeks of alpha-lipoic acid supplementation.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A trial of acute exercise before and after 4 weeks of placebo supplementation.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A trial of acute exercise before and after 4 weeks of placebo supplementation.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A trial of acute exercise before and after 4 weeks of placebo supplementation.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A trial of acute exercise before and after 4 weeks of placebo supplementation.
Study: NCT05865444

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Values alignment wise intervention
Description: The intervention includes: (1) reading materials, such as recent journalistic works that expose the deceptive and manipulative marketing practices of food companies and the harmful effects of these practices on society, with particular emphasis on harm to young children and the economically disadvantaged. Stories from other young people will also be included in order to contribute to the perception of widespread outrage and to suggest how that outrage can be channeled into taking a stand against the injustice perpetrated by food companies by eating less unhealthy or healthier food; (2) writing exercises, such as a story with a brief statement of what the participants would tell a younger child about the ads; and (3) an interactive activity, called Make It Real in which they are shown pictures of food ads and allowed to write and draw about them, making whatever changes (e.g., crossing out and substituting words) they feel necessary to make the ad real (i.e., no longer misleading).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational traditional intervention
Description: The educational intervention includes information on nutrition and physical exercise. It includes reading and writing exercises.
Study: NCT05445284

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group education sessions for parents plus usual diabetes care
Description: ≥3 in person/virtual group education sessions for parents in addition to usual diabetes care, every 3 months for 12 months

Intervention type: OTHER
Group type: OTHER
Intervention: Usual diabetes care
Description: Usual diabetes care, every 3-month for 12 months
Study: NCT05320562

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Kinesio taping
Description: Additionally, they received kinesio taping application for 7 days. Blue color kinesio tape (manufactured by Theraband®, USA) was used. Kinesio taping was done by experienced physiotherapist with 5 years of experience. Two Y shape bands were applied for lymphatic taping and to improve anterior upper leg muscle function (lymphatic correction and muscle correction techniques were integrated together).~Then two I shape bands (75-100% tension) were applied above the patella tendon and medial/lateral collateral ligaments in order to improve mechanoreceptor stimulation, proprioception and knee stability.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham taping
Description: Additionally, they received sham (placebo) taping: usual white patch was applied to the painful knee for 7 days. The technique of taping used was the same as in kinesiotaping group, but without stretching.
Study: NCT04924569

Intervention type: DEVICE
Intervention: Intermittent Catheter
Description: Flexible tubular device used to drain urine from the bladder via the urethra by male, female, and pediatrics.