TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05739175

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile Application with Interactive Nurse Support
Description: A mobile application containing an interactive nurse support program will be applied to the patients in the experimental group and its effect on patient outcomes will be evaluated through scales.~The mobile application consists of three modules. The first part is a learning module with videos on Covid 19, breast cancer and chemotherapy related side effects management. Second part is ask the nurse/doctor. Third part is patient experiences module.~After the participants download the mobile application to their phones, they can log in to the application with a valid e-mail address and password.
Study: NCT06192134

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CPM device
Description: CPM brace
Study: NCT04809766

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Mesothelin-specific TCR-T Cells
Description: Receive FH-TCR Tᴍsʟɴ IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Mesothelin-specific TCR-T Cells
Description: Receive FH-TCR Tᴍsʟɴ IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bendamustine
Description: Given IV
Study: NCT05706623

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apraglutide
Description: Single dose of apraglutide 5mg.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apraglutide
Description: Single dose of apraglutide 5mg.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apraglutide
Description: Single dose of apraglutide 5mg.
Study: NCT05433805

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting-mimicking diet (FMD) and physiotherapy
Description: FMD is a diet held monthly during five days with the restriction of calories to less than 1000 kcal, glucose and proteins.~Physiotherapy will be organized as home-based exercises explained by the physiotherapeutist at the beginning of the study.
Study: NCT05749666

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tofacitinib 5 MG
Description: Tofacitinib 5 MG BID taken orally for 24 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone
Description: Prednisolone taken daily according to preset tapering protocol

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo of tofacitinib 5mg
Description: Placebo of tofacitinib 5mg BID taken orally for 24 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo of prednisolone
Description: Placebo of prednisolone taken daily according to preset tapering protocol for 24 weeks
Study: NCT04810975

Intervention type: DEVICE
Group type: OTHER
Intervention: Muscle Strength Training
Description: Strength training occurring specific exercise regimens using Exercise Equipment A or B

Intervention type: DEVICE
Group type: OTHER
Intervention: Muscle Strength Training
Description: Strength training occurring specific exercise regimens using Exercise Equipment A or B
Study: NCT04929106

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mHealth support tool
Description: The final app is named Active Leisure and consists of an advanced activity planner based on the platform developed by the ideal company Smart Cognition AS. The app offers different interface options (symbols only, easy to read text, plain text, and read aloud). The activity planner will mostly be used by the individual with IDs and a support person (caregiver or health care provider). After completing an activity, a simple reward is available (e.g., a smiling face or to share a picture with other users of the app). The use of tailored communication through personalization: the use of individuals first name in the activity planner, adaptation: individually chosen activities, adjusted communication (symbols, easy-to-read text or plain text), preparation and planning, and feedback: rewarding and positive feedback (after activities have been performed) is expected to increase motivation, and thereby lead to higher levels of PA.
Study: NCT06778824

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Takepron
Description: Participants are expected to take a proton-pump inhibitor (PPI) for 12 weeks, with a dosage of 30 mg taken once a day.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zoloft 50Mg Tablet
Description: Participants are expected to take a selective serotonin reuptake inhibitor (SSRI) for 12 weeks, with a dosage of 50 mg taken once a day.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imipramine Pill
Description: Participants are expected to take tricyclic antidepressants (TCA) for 12 weeks, with a dosage of 25 mg taken twice a day.
Study: NCT06162377

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylnaltrexone
Description: Given by SC (injection)
Study: NCT05952024

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Patients will receive acalabrutinib orally with dosing schedule of X.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Patients will receive rituximab via IV infusion on Cycle 1 Day 15 and via SC injection on Day 1 of Cycle 2 through Cycle 8.
Study: NCT05241275

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyperpolarized 129 Xenon Gas Comparing Progressive Pulmonary Fibrosis Treatment
Description: Whether magnetic resonance imaging (MRI) using inhaled hyper-polarized 129 Xenon gas can help visualize impaired lung function to detect changes over time in Progressive Pulmonary Fibrosis
Study: NCT04176965

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FINEVISION HP IOL
Description: Cataractous lens will be removed in the study eyes and the FINEVISION HP IOL will be implanted in the capsular bag.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Alcon AcrySof SN60AT
Description: Cataractous lens will be removed in the study eyes and the Alcon AcrySof SN60AT IOL will be implanted in the capsular bag.
Study: NCT04868110

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High fiber diet
Description: A registered dietitian will delivered the lessons on consuming a high fiber diet to small groups to increased engage and material retention. These lessons will last 18 weeks.
Study: NCT05620108

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endotracheal Intubation at TOFC=1
Description: Intubation using a video laryngoscopy will be performed after train-of-four (TOFC) stimulation indicates neuromuscular blockade

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endotracheal Intubation 2 minutes after rocuronium administration
Description: Intubation using a video laryngoscopy will be performed 2 minutes after administration of rocuronium at 0.6 mg/kg (usual current clinical routine)
Study: NCT06419608

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BHV-7000
Description: BHV-7000 75 mg taken once daily for 6 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo taken once daily for 6 weeks
Study: NCT04674462

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CpG-adjuvanted HBV Vaccine
Description: Subjects receiving CpG-adjuvanted HBV vaccine will require two doses at 0 and 1 month after initiation. The second dose will be considered the same as the one month time point following the first dose.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional HBV Vaccine
Description: Subjects receiving traditional HBV vaccine series will require three doses at 0, 1, and 6 months after initiation. The second dose will be considered the same as the one month time point following the first dose.
Study: NCT06797492

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Shoulder Physical Examination
Description: shoulder physical examination is conducted to assess the patient's musculoskeletal condition and to track progress throughout the rehabilitation phases

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Shoulder Rehabilitation in a Virtual Environment
Description: The rehabilitation protocol for shoulder disorders is executed using a Virtual Reality (VR) system, where patients perform customized exercises tailored to their physical characteristics.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usability assessment and presence and co-presence evaluation
Description: The usability of the VR system, along with the sense of presence and co-presence during rehabilitation, is assessed using validated scales
Study: NCT06795789

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitals+ (combined multivitamin and polyphenol supplement)
Description: Multivitamin with 19 essential nutrients combined with Bilberry polyphenols
Study: NCT06794840

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction.
Description: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) that uses an EMA-based machine learning (ML) algorithm to anticipate chemsex risk and deliver appropriate chemsex-related harm reduction and HIV prevention services when the risk is detected.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction.
Description: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) that uses an EMA-based machine learning (ML) algorithm to anticipate chemsex risk and deliver appropriate chemsex-related harm reduction and HIV prevention services when the risk is detected.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction.
Description: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) that uses an EMA-based machine learning (ML) algorithm to anticipate chemsex risk and deliver appropriate chemsex-related harm reduction and HIV prevention services when the risk is detected.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction.
Description: JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) that uses an EMA-based machine learning (ML) algorithm to anticipate chemsex risk and deliver appropriate chemsex-related harm reduction and HIV prevention services when the risk is detected.
Study: NCT06796140

Intervention type: OTHER
Intervention: Visible Light Exposure - Treated zone - Left hemi-back
Description: The treated zone located on the left side of the hemi-back was exposed to Visible Light with the simulator 1 to induce skin pigmentation (144J/cm2), 15 to 30 minutes after application.

Intervention type: OTHER
Intervention: Visible Light Exposure - Treated zone - Right hemi-back
Description: The treated zone located on the right side of the hemi-back was exposed to Visible Light with the simulator 2 to induce skin pigmentation (144J/cm2), 15 to 30 minutes after application.

Intervention type: OTHER
Intervention: Visible Light Exposure - Untreated zone - Left hemi-back
Description: The untreated zone located on the left side of the hemi-back was exposed to Visible Light with the simulator 1 to induce skin pigmentation (144J/cm2), as the same time as the treated zone.

Intervention type: OTHER
Intervention: Visible Light Exposure - Untreated zone - Right hemi-back
Description: The untreated zone located on the right side of the hemi-back was exposed to Visible Light with the simulator 2 to induce skin pigmentation (144J/cm2), as the same time as the treated zone.
Study: NCT06793865

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Russian Current Stimulation for Anterior Tibial Group
Description: Parameters were adjusted as the following frequency of 2.5 kHz and 50 bursts per second with 50 pulses per burst. The stimulus was applied for a 10 seconds on period followed by a 10 seconds off period for total treatment time 20 minutes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Russian Current Stimulation for Anterior Tibial Group
Description: Placebo Russian current stimulation was applied to the anterior tibial group without active current for 20 minutes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Selected physical therapy exercise for both limbs
Description: The selected physical therapy exercise for both limbs was applied for 40 minutes, including passive, active assisted and active range of motion exercises, stretching of spastic muscles, strengthening of weak muscles (anterior tibial group), and finally functional mobility exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Selected physical therapy exercise for both limbs
Description: The selected physical therapy exercise for both limbs was applied for 40 minutes, including passive, active assisted and active range of motion exercises, stretching of spastic muscles, strengthening of weak muscles (anterior tibial group), and finally functional mobility exercises.
Study: NCT06793280

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: intraoperative ICG angiography
Description: Intraoperative ICG angiography to evaluate colonic perfusion

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: No intraoperative ICG angiography
Description: Visual evaluation of colonic perfusion
Study: NCT06794476

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Milieu Teaching-AV
Description: In Milieu Teaching-AV, coaches will teach caregivers to engage the child in play or routines around a standardized set of toys, follow the child's attention or communication lead around these toys, and respond to the infant's communication acts by modeling and expanding those communication acts into more sophisticated strategies. While responding to infant communication acts, coaches will slowly move the referent of the infant's lead near the face at approximately the level of the mouth, wait for the infant to shift his/her gaze towards the new referent position if necessary, and provide all models, prompting, and expanding while maintaining placement of the referent near the mouth.
Study: NCT06792929

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality glasses group
Description: Patients will wear virtual reality glasses throughout the ultrasound-guided fine needle aspiration biopsy procedure.
Study: NCT06793631

Intervention type: OTHER
Intervention: Participants will be interviewed qualitatively about experience of providing/receiving financial support for living costs
Description: There is no intervention for participants. Participants will receive qualitative interviews to explore their experience of financial insecurity

Intervention type: OTHER
Intervention: Participants will be interviewed qualitatively about experience of providing/receiving financial support for living costs
Description: There is no intervention for participants. Participants will receive qualitative interviews to explore their experience of financial insecurity

Intervention type: OTHER
Intervention: Participants will be interviewed qualitatively about experience of providing/receiving financial support for living costs
Description: There is no intervention for participants. Participants will receive qualitative interviews to explore their experience of financial insecurity
Study: NCT06796166

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AI-Supported Preoperative Education
Description: This intervention involves the use of a pre-trained AI-powered education platform designed to provide preoperative information to patients undergoing mastectomy. The program delivers structured, interactive education that includes details about the surgical process, postoperative care, and emotional coping strategies. The pre-trained AI system offers standardized responses to patient questions, ensuring consistency and clarity in the information provided, with the goal of reducing fear and anxiety.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Preoperative Education
Description: This intervention consists of standard preoperative education provided by healthcare professionals. Patients receive general information about the surgical procedure, postoperative care, and strategies to manage fear and anxiety. The education is delivered in a traditional, face-to-face format without the use of AI or digital tools.
Study: NCT06795373

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ritlecitinib
Description: Once daily dose of 100mg of ritlecitinib taken orally for 12 weeks
Study: NCT06792760

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy
Description: The intervention will consist of 10 individual physiotherapy sessions delivered by a single physiotherapist trained in FMD. The physiotherapy programme will include education, movement retraining and a self-management plan.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy
Description: The intervention will consist of 10 individual physiotherapy sessions delivered by a single physiotherapist trained in FMD. The physiotherapy programme will include education, movement retraining and a self-management plan.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Specific Breathing Techniques
Description: The intervention will include education and training in specific breathing techniques, which will be exercised by the patient as a self-management plan for over 5-10 minutes daily.
Study: NCT06794762

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional exercises
Description: Aerobic exercise and stretching exercises will be applied in the conventional exercise program.~A 20-30 minute walking will be done as aerobic exercise. Stretching exercises will be done for major muscle groups in 3 sets and 10 repetitions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core stabilization exercises in addition to conventional exercises
Description: In addition to the conventional exercise program, core stabilization exercises will be applied. During the exercises, participants will be trained on neutralizing the spine and working the transverse abdominis and multifidus muscles, correct postural control, and performing the exercises with diaphragmatic breathing.
Study: NCT05237531

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standardized Preoperative Education
Description: The standardized preoperative education includes a brief video, an interactive quiz, and a written handout.~The video will provide information on the proper use and common side effects of opioid pain medications, the expected effects of a peripheral nerve block, and the concept of multimodal postoperative pain management with non-opioid medications and non-pharmaceutical pain management strategies. The interactive quiz will reinforce the critical components of the video in a question-and-answer format which requires active participation. The written handout will summarize the educational content in a form which can be easily referenced by patients at home.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Education per provider preference (no standardization, current standard of care)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Preoperative and postoperative questionnaires
Description: Preoperative questionnaire: Demographic questions plus specific questions about chronic pain, prior opioid use, and mental health diagnoses Postoperative questionnaire: Questions about pain control after surgery, satisfaction with pain control, healthcare contact since surgery, opioid consumption since surgery, and satisfaction with education

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Preoperative and postoperative questionnaires
Description: Preoperative questionnaire: Demographic questions plus specific questions about chronic pain, prior opioid use, and mental health diagnoses Postoperative questionnaire: Questions about pain control after surgery, satisfaction with pain control, healthcare contact since surgery, opioid consumption since surgery, and satisfaction with education
Study: NCT06795776

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eschscholzia tablets
Description: The intervention will be provided as swallowable Eschscholzia tablets (1.0 g) containing 0.503g Eschscholzia californica Herba rec. tinct. conc. as the active pharmaceutical ingredient (API) corresponding 600 mg powdered herbal material.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Tablets
Description: A placebo tablet will be provided that matches the verum in its optical and sensorial properties and posology. Contains: microcrystalline cellulose, Colloidal anhydrous silica, glycerol distearate, caramel couleur and colorants.
Study: NCT06797076

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health enSuite Headache
Description: The program consists of treatment modules delivered over 8 weeks. Modules include topics such as Headaches and Triggers, Relaxation, Breathing, Changing Thoughts, Imagery, Problem Solving, Nutrition, Sleep, Exercise, Medication, and more. Each module features sections like Goals, Getting Started, Let's Talk, and a Quiz, with Let's Practice in four modules. Intervention participants track headaches using a structured tracker to log impacts, daily events (e.g., exposure, strategies, medication), and notes. Control group participants track headaches only at baseline, two months, and five months post-randomization. Weekly reminders (nudges) encourage app usage, with the same frequency for all users. Reports summarizing daily headache data are available to participants and healthcare providers.
Study: NCT06793176

Intervention type: DIAGNOSTIC_TEST
Intervention: Video capture
Description: A 20-second video capture of head-neck movements at high frame rates is conducted for all participants to obtain high-resolution images. The captured videos are analyzed using an algorithm based on Vibraimage technology to infer whether the participants have depression.

Intervention type: DIAGNOSTIC_TEST
Intervention: Video capture
Description: A 20-second video capture of head-neck movements at high frame rates is conducted for all participants to obtain high-resolution images. The captured videos are analyzed using an algorithm based on Vibraimage technology to infer whether the participants have depression.
Study: NCT06797427

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DPH001
Description: 100 mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nexavar (Sorafenib)
Description: 200 mg
Study: NCT06795022

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD9793 Intravenous (IV) monotherapy
Description: T cell-engaging antibody that targets GPC3 on tumour cells

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD9793 Subcutaneous (SC) monotherapy)
Description: T cell-engaging antibody that targets GPC3 on tumour cells