TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06730347

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lorigerlimab
Description: Bispecific DART protein binding PD-1 and CTLA-4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lorigerlimab
Description: Bispecific DART protein binding PD-1 and CTLA-4
Study: NCT06210373

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Myrialen Gel
Description: Myrialen Gel will be instilled as 1 drop per eye 3 times a day and one drop per eye before going to bed in the conjunctival sac for 30 days.In case of bilateral dry eye syndrome, both eyes will be treated. In case of monolateral dry eye syndrome, the decision to treat both eyes will be taken according to the Investigator's judgment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Recugel
Description: Recugel will be instilled as 1 drop per eye 3 times a day and one drop per eye before going to bed in the conjunctival sac for 30 days.~In case of bilateral dry eye syndrome, both eyes will be treated. In case of monolateral dry eye syndrome, the decision to treat both eyes will be taken according to the Investigator's judgment.
Study: NCT05960149

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: using Indocyanine Green
Description: Nerve-sparing robot-assisted laparoscopic radical prostatectomy using Indocyanine Green

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nerve-sparing robot-assisted laparoscopic radical prostatectomy
Description: Nerve-sparing robot-assisted laparoscopic radical prostatectomy without the use of Indocyanine Green
Study: NCT04848259

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Saline will be applied after surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Dexamethason will be given IV before surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Honey
Description: Honey will be applied locally after surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone and honey
Description: Dexamethason will be given IV before surgery and then Honey will be applied locally after surgery
Study: NCT04990401

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Activation Teletherapy
Description: A total of 10 teletherapy sessions to be delivered over 12-14 weeks, designed to increase physical activity among depressed individuals.
Study: NCT06155513

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Omega-3 monoglyceride based topical Serum and cream of formulation A (light)
Description: Omega-3 monoglyceride based serum and cream of lighter formulation

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Omega-3 monoglyceride based topical Serum and cream of formulation B (rich)
Description: Omega-3 monoglyceride based serum and cream with a richer formulation
Study: NCT05551689

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psychostimulant
Description: All enrolled patients should be receiving ADHD pharmacological treatment (psychostimulants)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psychostimulant
Description: All enrolled patients should be receiving ADHD pharmacological treatment (psychostimulants)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psychostimulant
Description: All enrolled patients should be receiving ADHD pharmacological treatment (psychostimulants)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FOCUS ADHD App
Description: FOCUS ADHD is a mobile health application to support ADHD treatment adherence, monitoring and psychoeducation. The App was developed by the Attention Deficit Hyperactivity Disorder Program (ProDAH) of the Hospital de Clínicas de Porto Alegre (HCPA) and the Federal University of Rio Grande do Sul (UFRGS)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FOCUS ADHD App
Description: FOCUS ADHD is a mobile health application to support ADHD treatment adherence, monitoring and psychoeducation. The App was developed by the Attention Deficit Hyperactivity Disorder Program (ProDAH) of the Hospital de Clínicas de Porto Alegre (HCPA) and the Federal University of Rio Grande do Sul (UFRGS)
Study: NCT05054699

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Seizure Therapy
Description: Subjects will receive a train of magnetic pulses (between 600 and 1400 pulses) at 100Hz under general anaesthesia using a Magventure device with a Twin Coil

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electroconvulsive Therapy
Description: Subjects will receive a brief-pulse electrical stimulus (between 25 and 1008mC) under general anaesthesia using a ECT device
Study: NCT06025994

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MULTI-DOMAIN LIFESTILE INTERVENTION
Description: All participants in the multi-domain lifestyle group will receive five different kinds of intervention: i) strict management of CV and metabolic risk factors, ii) tailoring of medical therapy on the basis of the invasive assessment of CMD and coronary vasomotion, iii) exercise training iv) dietary counselling, v) psychological intervention.
Study: NCT05192564

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise for bilateral or unilateral vestibular hypofunction patients
Description: Physical Activity intervention with balance exercises, multidirectional displacements, and strength with postural control, implementing 8-10 exercises integrating the main muscle groups and motor patterns, aerobic exercise on bicycle (15 min) developed progressively in intensity (R1-mild, R2-moderate, R3-vigorous) implementing an intervallic design in low volume.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional rehabilitation treatment
Description: Vestibular rehabilitation exercises counseling

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional rehabilitation treatment
Description: Vestibular rehabilitation exercises counseling
Study: NCT05294406

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine
Description: Pregnant women attending routine antenatal care visits in their second and third trimester are given monthly IPTp consisting of a treatment dose of dihydroartemisinin-piperaquine (3 tablets per day for 3 days, 9 tablets total)
Study: NCT06294665

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pericapsular Nerve Group (PENG) Block
Description: The PENG block will be performed ,the patient is placed in the supine position , the procedural leg is slightly abducted, the curvilinear low-frequency ultrasound probe will be placed over the line parallel to the inguinal ligament. It will subsequently rotated 45◦ to identify the anterior inferior iliac spine, the iliopubic eminence, and the psoas tendon. A 22-gauge, 80 mm echogenic needle will inserted in an in-plane approach to place the tip in the musculofascial plane between the pubic ramus posteriorly and the psoas tendon anteriorly. Following negative aspiration, by one of the two syringes each one has a serial number corresponding to each group.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pericapsular Nerve Group (PENG) Block
Description: The PENG block will be performed ,the patient is placed in the supine position , the procedural leg is slightly abducted, the curvilinear low-frequency ultrasound probe will be placed over the line parallel to the inguinal ligament. It will subsequently rotated 45◦ to identify the anterior inferior iliac spine, the iliopubic eminence, and the psoas tendon. A 22-gauge, 80 mm echogenic needle will inserted in an in-plane approach to place the tip in the musculofascial plane between the pubic ramus posteriorly and the psoas tendon anteriorly. Following negative aspiration, by one of the two syringes each one has a serial number corresponding to each group.
Study: NCT05622227

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Drug: 68Ga-P16-093
Description: Intravenous injection of 68Ga-P16-093 with the dosage of 1.5-1.8 MBq (0.04-0.05 mCi)/kg. Tracer doses of 68Ga-P16-093 will be used to image lesions of breast cancer by PET/CT.
Study: NCT06436391

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesio taping
Description: Kinesio taping will be applied to the lateral part of the baby's heel to increase blood flow. Blood collection will always be performed by the same nurse

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ShotBlocker
Description: Shotblocker will be applied to the baby's heel average 10-15 seconds with minimal pressure.
Study: NCT06356818

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy program
Description: Physiotherapy and rehabilitation treatment program will be applied to the patients. In this program, a 30-40-minute exercise protocol covering proprioceptive, balance and strengthening exercises will be implemented. For a total of 12 sessions, 3 days a week, over a 4-week period

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy program
Description: Physiotherapy and rehabilitation treatment program will be applied to the patients. In this program, a 30-40-minute exercise protocol covering proprioceptive, balance and strengthening exercises will be implemented. For a total of 12 sessions, 3 days a week, over a 4-week period

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy program
Description: Physiotherapy and rehabilitation treatment program will be applied to the patients. In this program, a 30-40-minute exercise protocol covering proprioceptive, balance and strengthening exercises will be implemented. For a total of 12 sessions, 3 days a week, over a 4-week period

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality (VR)
Description: virtual reality (VR) program will be applied using balance and strengthening games by Nintendo Wii Fit Plus; warm-up exercise (5 minutes), workout (20 minutes) and cool-down exercise (5 minutes) for a total of 30 minutes. For a total of 12 sessions, 3 days a week, over a 4-week period

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality (VR)
Description: virtual reality (VR) program will be applied using balance and strengthening games by Nintendo Wii Fit Plus; warm-up exercise (5 minutes), workout (20 minutes) and cool-down exercise (5 minutes) for a total of 30 minutes. For a total of 12 sessions, 3 days a week, over a 4-week period

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Motor imagery (MI)
Description: Patients will be introduced to explicit Motor imagery program which the content of the imagery program will last 20 minutes in total, with 5 minutes of relaxation and 15 minutes of imagery training. For a total of 12 sessions, 3 days a week, over a 4-week period.
Study: NCT06536322

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: OHS-interRAI
Description: An oral health screening tool is being tested. Former name was the optimized oral health-related section of the interRAI (ohr-interRAI). This was further optimized into the OHS-interRAI. The OHS-interRAI comprises of 3 oral health-related items that are assessed through questioning the resident, and 6 items that require visual inspection of the mouth.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: OHS-interRAI
Description: An oral health screening tool is being tested. Former name was the optimized oral health-related section of the interRAI (ohr-interRAI). This was further optimized into the OHS-interRAI. The OHS-interRAI comprises of 3 oral health-related items that are assessed through questioning the resident, and 6 items that require visual inspection of the mouth.
Study: NCT05786638

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Allergen Immunotherapy Extract
Description: Sublingual subcutaneous allergen immunotherapy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Allergen Immunotherapy Extract
Description: Sublingual subcutaneous allergen immunotherapy
Study: NCT05030636

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acute moderate to vigorous exercise performed at a specific moment of the day
Description: Treadmill (30 minutes) at 70% of maximal aerobic capacity

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acute moderate to vigorous exercise performed at a specific moment of the day
Description: Treadmill (30 minutes) at 70% of maximal aerobic capacity
Study: NCT05039801

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glutaminase-1 Inhibitor IACS-6274
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glutaminase-1 Inhibitor IACS-6274
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glutaminase-1 Inhibitor IACS-6274
Description: Given by PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given by IV (vein)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capivasertib
Description: Given by PO
Study: NCT04893460

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CoQuit App
Description: The CoQuit App is a cognitive dissonance based app for smoking cessation.
Study: NCT05691959

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients randomized to placebo group will receive Normal Saline 50ml IV.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium
Description: Patients randomized to the study group will receive Calcium 2gm in Normal Saline 50ml IV.
Study: NCT06497504

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bepirovirsen
Description: Bepirovirsen will be administered.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered.
Study: NCT05731167

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multidomain frailty prevention method
Description: We use the nutrition, physical training, medication consultation, cognition training to prevent the occurrence of frailty or other adverse outcome.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regular follow up
Description: Subjects will receive regular follow up and suggestion in outpatient department.
Study: NCT06510920

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: The mixed design scheme of football and volleyball sports technology and competition will be adopted.aerobic exercise intensity will be moderate-intensity aerobic exercise load , and the intervention time was 12 weeks, 60 minutes each time, twice a week. The main preparation activities were jogging and special preparation activities (10 minutes), and the main part was technical teaching combined with competition (60 minutes).The end part is mostly jogging and stretching (10 minutes). Two subjects in each group were selected to wear Decathlon Bluetooth heart rate band, and the exercise intensity was controlled by detecting the heart rate of the subjects.
Study: NCT06261541

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ABLE Exoskeleton
Description: Participants with MS will undergo a training program with the ABLE Exoskeleton device: a total of 10 sessions, distributed 1-2 sessions/week for up to 11 weeks.
Study: NCT05621967

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tonation Breathing Techniques
Description: Tonation and Breathing Techniques (TBT): consist of a combination of organic inhalation and controlled exhalation with tonation. This will be guided by a trained facilitator, and the entire exercise will take 20 minutes. This will include guided relaxed breathing, mindful breathing, patterned tonation, nasal tonation, and pursed lip tonation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tonation Breathing Techniques
Description: Tonation and Breathing Techniques (TBT): consist of a combination of organic inhalation and controlled exhalation with tonation. This will be guided by a trained facilitator, and the entire exercise will take 20 minutes. This will include guided relaxed breathing, mindful breathing, patterned tonation, nasal tonation, and pursed lip tonation.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music Driven Vocal Exercises
Description: Music Driven Vocal Exercises (MDVE): A Music Therapy procedure will be implemented by a trained facilitator, utilizing an accompanying instrument (ie, guitar or Autoharp) and moving stepwise up and down within a scale of 8 whole steps. The total length of the procedure is 20-25 minutes. This will include vocal exercises, and melodic exercises alternating with speaking,

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music Driven Vocal Exercises
Description: Music Driven Vocal Exercises (MDVE): A Music Therapy procedure will be implemented by a trained facilitator, utilizing an accompanying instrument (ie, guitar or Autoharp) and moving stepwise up and down within a scale of 8 whole steps. The total length of the procedure is 20-25 minutes. This will include vocal exercises, and melodic exercises alternating with speaking,

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Silent Breathing
Description: Patient will sit in a quiet room and focus on silent breathing x 20 min.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Silent Breathing
Description: Patient will sit in a quiet room and focus on silent breathing x 20 min.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Silent Breathing
Description: Patient will sit in a quiet room and focus on silent breathing x 20 min.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Silent Breathing
Description: Patient will sit in a quiet room and focus on silent breathing x 20 min.
Study: NCT05971628

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: RAPID procedure
Description: RAPID procedure stands for Resection And Partial Liver Transplantation with Delayed Hepatectomy for hepatocellular carcinoma
Study: NCT04733898

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SamenSpelen.app
Description: An app designed to play simple, social games in a chat environment. These games are designed to elicit personal interaction.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: FijnSpelen.app
Description: An app designed to play simple, social games in a chat environment. These games are designed to not elicit personal interaction.
Study: NCT05336513

Intervention type: OTHER
Group type: OTHER
Intervention: Diet Control
Description: Diet following mediterranean principles, for 15 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet anti-inflammatory
Description: Diet combining food items with anti-inflammatory potential, following the principles described in Rondanelli, Clinical Nutrition, 2021 Mar;40(3):661-689. doi: 10.1016/j.clnu.2020.08.020.
Study: NCT05219929

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tetracycline 500 Mg
Description: 500 mg three times daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tetracycline 500 Mg
Description: 500 mg three times daily

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo for Tetracycline given same way as Tetracycline.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo for Tetracycline given same way as Tetracycline.
Study: NCT05082844

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MRI assessment
Description: Evaluation of the clinical-radiological results from the case series of patients surgically treated for cuff rotator lesions from 2009 to 2020 at the Shoulder-Elbow Department . At 12 months the result is considered stabilized, so we will proceed to collect all case histories that have passed this follow-up period.
Study: NCT05715736

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: APB-R3
Description: APB-R3 is formulated as a sterile solution containing APB-R3 as the active substance administered intravenously.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.90% Normal Saline only
Study: NCT06097273

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1083
Description: Suspension for injection
Study: NCT06168162

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: titated PEEP to best static compliance
Description: the Intraoperative PEEP will be titrated to best static compliance for each patient

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: titated PEEP to best static compliance
Description: the Intraoperative PEEP will be titrated to best static compliance for each patient
Study: NCT06403098

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: External Nasal Dilator Strip
Description: Participants will wear an extra strength Breathe Right nasal strip overnight.
Study: NCT04991688

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BOTOX-A
Description: 10 injections of 20 U of toxin will be made into the rectum 5, 10 and 15 cm above the pectinate line. At each level, 3 injections of 20 U will be performed in the submucosa, circumferentially.The last injection is made 20 cm above the pectinate line. Total does not exceed 200U of Botox-A
Study: NCT05330351

Intervention type: DIAGNOSTIC_TEST
Intervention: Gastric Ultrasound
Description: The investigators will compare gastric fluid volume as determined by ultrasound pre-induction vs. gastric volume aspirated via an orogastric tube post-intubation. The results will be stratified into low risk, moderate risk and high risk for aspiration based on ultrasound exam by an investigator off-line.
Study: NCT04839614

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY-Referral
Description: See arm description
Study: NCT05734742

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational video
Description: There were two videos including the first video Sleep apnea Syndrome Driving Safety Picture Scroll and the second video Sleep apnea Syndrome and Traffic Accidents. The first video was approximately 3 minutes long. This video was suitable for all ages. It was an easy-to-understand video explaining the characteristics of OSA and its relationship with traffic accidents. The second video was the detailed video, which is approximately 20 minutes in duration. This video was suitable for those who desire to learn more about OSA. It can be used in various educational settings, including internal training and traffic safety workshops. Participants must watch at least the first video.
Study: NCT04793581

Intervention type: DEVICE
Group type: OTHER
Intervention: Atherectomy
Description: Directional atherectomy of lesions below the knee.
Study: NCT06414005

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TPX-115
Description: Ultrasound-guided intratendinous injection of allogeneic fibroblasts (TPX-115)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Saline)
Description: Ultrasound-guided intratendinous placebo injection
Study: NCT05643443

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gradual increase of force
Description: steady force