TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04080180

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Contingency Management
Description: Contingency management (CM) is a behavioral method that employs external rewards for target behavior. For this study, participants will receive gift cards for adhering to Medication-Assisted Treatment (attending physician visits and adhering to buprenorphine-naloxone as determined by urine toxicology panel) during their first four visits while randomized to this condition. Participants will draw a gift card from a fishbowl each visit they are adherent. Gift cards range from $25-$100.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Contingency Management
Description: Contingency management (CM) is a behavioral method that employs external rewards for target behavior. For this study, participants will receive gift cards for adhering to Medication-Assisted Treatment (attending physician visits and adhering to buprenorphine-naloxone as determined by urine toxicology panel) during their first four visits while randomized to this condition. Participants will draw a gift card from a fishbowl each visit they are adherent. Gift cards range from $25-$100.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brief Motivational Interviewing + Substance Free Activities + Mindfulness
Description: Brief Motivational Interviewing + Substance Free Activities + Mindfulness (BSM) is an intervention that uses Motivational Interviewing and Behavioral Economics strategies to increase the salience of delayed rewards by eliciting personal goals, developing opioid-free activities, and engaging in reward bundling and episodic future thinking. Participants will be offered a menu of substance free activities that has been developed in pilot work. Activities will be discussed, and participants will be asked to engage in selected activities as homework. Engagement in substance free activities will be assessed at each subsequent visit. Mindfulness components will also be included in the intervention.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brief Motivational Interviewing + Substance Free Activities + Mindfulness
Description: Brief Motivational Interviewing + Substance Free Activities + Mindfulness (BSM) is an intervention that uses Motivational Interviewing and Behavioral Economics strategies to increase the salience of delayed rewards by eliciting personal goals, developing opioid-free activities, and engaging in reward bundling and episodic future thinking. Participants will be offered a menu of substance free activities that has been developed in pilot work. Activities will be discussed, and participants will be asked to engage in selected activities as homework. Engagement in substance free activities will be assessed at each subsequent visit. Mindfulness components will also be included in the intervention.
Study: NCT06139341

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 765845
Description: BI 765845

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05174455

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib Tosylate Monohydrate
Description: Given PO
Study: NCT05166187

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Practice Advisory
Description: Patients in this arm will have a Best Practice Advisory displayed in the Electronic Medical Record (EMR) as part of the discharge order workflow.
Study: NCT04974242

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapist-led exercise
Description: A programme of physiotherapist-led exercise over approximately 12 weeks.
Study: NCT04506164

Intervention type: OTHER
Group type: OTHER
Intervention: Multicomponent Implementation Strategy
Description: The eScreening MCIS was developed over the past seven years and consists of: 1) eScreening software provision, 2) training, 3) RPIW, and 4) ongoing blended facilitation. The investigators developed our MCIS to address specific eScreening implementation barriers found in the investigators' prior research.

Intervention type: OTHER
Group type: OTHER
Intervention: eScreening
Description: eScreening is a clinical patient self report system that allows Veterans to complete clinical reminders and other self report screens using a secure connection from any internet connected device.
Study: NCT05527041

Intervention type: DEVICE
Intervention: EyeBOX Lens (EBLens)
Description: The investigational device, EBLens, consists of eye-tracking scanners and sensors, developed by AdHawk Microsystems, embedded into a rugged pair of eye-glasses. The subject will wear the EBLens form factor while seated about 40 cm from a small handheld computer screen. The subject will be instructed to watch a video on the screen, while trying not to move their head. The operator will then initiate the EBLens test sequence. During this test a video will be displayed on only a portion of the screen (aperture about 1/9 the size of the screen) for 90 seconds. The video aperture will begin in the upper left corner, and, after 10 seconds, moves in a clockwise direction around the screen for 2 cycles, each taking 40 seconds. During the scan, the following data are collected at a frame rate from 100 to 500 Hz:~* Gaze coordinates~* Pupil sizes~* Accelerometer data~* Gyroscopic data~* Rotation data~* Blink data

Intervention type: DEVICE
Intervention: EyeBOX Lens (EBLens)
Description: The investigational device, EBLens, consists of eye-tracking scanners and sensors, developed by AdHawk Microsystems, embedded into a rugged pair of eye-glasses. The subject will wear the EBLens form factor while seated about 40 cm from a small handheld computer screen. The subject will be instructed to watch a video on the screen, while trying not to move their head. The operator will then initiate the EBLens test sequence. During this test a video will be displayed on only a portion of the screen (aperture about 1/9 the size of the screen) for 90 seconds. The video aperture will begin in the upper left corner, and, after 10 seconds, moves in a clockwise direction around the screen for 2 cycles, each taking 40 seconds. During the scan, the following data are collected at a frame rate from 100 to 500 Hz:~* Gaze coordinates~* Pupil sizes~* Accelerometer data~* Gyroscopic data~* Rotation data~* Blink data
Study: NCT04801758

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Analytical Treatment Interruption
Description: Participants will stop taking their HIV medication and will stay off HIV medication unless and until the HIV levels in their blood show that their immune system is not controlling their HIV or they meet other ART re-start criteria as noted in section Detailed Description.
Study: NCT04852861

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: immunogenicity after first and second dose
Description: Humoral and cellulair immunity after first and second dose of the different vaccines administrated.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: immunogenicity after first and second dose
Description: Humoral and cellulair immunity after first and second dose of the different vaccines administrated.
Study: NCT04721678

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interpersonal psychotherapy
Description: Internet-based interpersonal psychotherapy aimed at reducing symptoms of depression. The content of the intervention is divided into three parts: the assessment phase (the first four weeks), the focus phase (the following five weeks), and the end phase (the last week).
Study: NCT05490862

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Modification
Description: An individualized low-calorie diet is characterized by sugars and starchy food intake restriction, 500 kcal daily energy deficit for 12 weeks (3 months).~Regular physical activity is represented by individualized 30 minutes trainings on an anti-gravity treadmill 3 workouts per week for 12 weeks with individual targets of stepping activity, which will be evaluated according to personal fitness monitoring data

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Recommendations
Description: The list of traditional diet and physical activity recommendations for patients with obesity
Study: NCT06352541

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PRO-232
Description: Moxifloxacin 0.5% and Dexamethasone Phosphate 0.1%

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sodium Chloride 0.9%
Study: NCT06413485

Intervention type: BEHAVIORAL
Intervention: Level of recreational water contact activities
Description: We will examine a graded classification of this exposure based on individuals' minimum level of water contact: 1) no water contact; 2) minimal contact; 3) body immersion; 4) swallowed water. Minimal contact is defined as water contact that does not result in body immersion (e.g., wading below one's waist, boating, fishing). Body immersion is defined as entering the water above one's waist (e.g., swimming, surfing, snorkelling), and swallowing water as ingestion of any amount of water.
Study: NCT05800223

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Almonertinib
Description: The dosage is 110 mg/day (2 tablets/day) orally once a day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Almonertinib
Description: The dosage is 110 mg/day (2 tablets/day) orally once a day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Almonertinib
Description: The dosage is 110 mg/day (2 tablets/day) orally once a day

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SBRT
Description: SRT, 27Gy-40Gy/3-5f

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SBRT
Description: SRT, 27Gy-40Gy/3-5f
Study: NCT05470387

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LB1148
Description: A total of 700 mL of drug product will be administered orally as a split dose before surgery.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A total of 700 mL of placebo will be administered orally as a split dose before surgery.
Study: NCT06339151

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone before surgery
Description: Dexamethasone 0.15 mg/kg IV before surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone before and 12 hours after surgery
Description: Dexamethasone 0.15 mg/kg IV before surgery Dexamethasone 0.15 mg/kg IV at 12 hours post operation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone before and 24 hours after surgery
Description: Dexamethasone 0.15 mg/kg IV before surgery Dexamethasone 0.15 mg/kg IV at 24 hours post operation
Study: NCT04684264

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heart Failure Prevention Clinic
Description: Heart Failure Prevention Clinic is a pharmacist-directed practice in collaboration with an attending cardiologist that uses evidence-based guidelines to optimize medications and lifestyle interventions for heart failure prevention.
Study: NCT06112483

Intervention type: BEHAVIORAL
Intervention: SWELE Programme
Description: This 16-week programme focuses on Supporting Wellness in E-Child Learning Environments (SWELE) programme by combining unstructured outdoor play with mindfulness-based interventions to promote mental health in SEN students, in the context of the COVID-19 pandemic. There is no such SWELE programme to promote mental health for SEN students in Hong Kong, especially in the context of COVID-19 pandemic.~A playful approach of unstructured play has also been found effective on promoting positive emotions and emotional competence among early adolescents (Harn \& Bo, 2019). Unstructured Outdoor Play coupled with Mindfulness-based Interventions via SWELE programme to Promote Mental Health for children and adolescents with SEN during COVID-19 pandemic. Very limited unstructured outdoor play-based programme integrated into the extra-curricular activities in the special schools in Hong Kong.
Study: NCT05256680

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Gardening Activities
Description: In the research, the elderly in the experimental group will have gardening activities once a week for 3 months.~No intervention will be applied to the elderly in the control group during the research. They will participate in routine activities in the nursing home.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gardening Activities
Description: In the research, the elderly in the experimental group will have gardening activities once a week for 3 months.~No intervention will be applied to the elderly in the control group during the research. They will participate in routine activities in the nursing home.
Study: NCT05201404

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Namodenoson
Description: Adenosine A3 Receptor (A3AR) agonist

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Control arm
Study: NCT06322563

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LTC004+regorafenib
Description: LTC004,90μg/kg,IV,Day 1,Q3W; Regorafenib:Orally once daily for the first 21 days of each cycle, with 28 days as 1 cycle. Cycle 1 was dose-escalation with a starting dose of 80 mg/d, increasing by 40 mg per week until 160 mg/d, i.e., 80 mg/d in week 1 (D1\~D7), 120 mg/d in week 2 (D8\~D14), and 160 mg/d in week 3 (D15\~D21);

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LTC004+regorafenib
Description: LTC004,90μg/kg,IV,Day 1,Q3W; Regorafenib:Orally once daily for the first 21 days of each cycle, with 28 days as 1 cycle. Cycle 1 was dose-escalation with a starting dose of 80 mg/d, increasing by 40 mg per week until 160 mg/d, i.e., 80 mg/d in week 1 (D1\~D7), 120 mg/d in week 2 (D8\~D14), and 160 mg/d in week 3 (D15\~D21);
Study: NCT05259735

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Clinical Guideline based Management
Description: Clinical guidline based management will be done for Type 2 diabetes Mellitus

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Comparator
Description: In this arm usual management of T2DM without any clinical guideline
Study: NCT06527014

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulse Radiofrequency to the suprascapular nerve
Description: Pulse radiofrequency ablation to the Suprascapular nerve
Study: NCT05824364

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telerehabilitation
Description: Telerehabilitation activites will be tested with the aim to provide 1) continuation of rehabilitative care, focused on physical training and patients'monitoring , and 2) information in the mid-term about study goals.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rehabilomic
Description: blood withdrawal (10 ml of blood, two tubes of 5 ml for serum isolation): at the hospital admission at the Cardiac Rehabilitation Unit of IRCCS Fondazione Don Gnocchi of Milan (T0) and after the rehabilitative treatment (T1)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: rehabilomic
Description: blood withdrawal (10 ml of blood, two tubes of 5 ml for serum isolation): at the hospital admission at the Cardiac Rehabilitation Unit of IRCCS Fondazione Don Gnocchi of Milan (T0) and after the rehabilitative treatment (T1)
Study: NCT05771649

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based intervention
Description: A mindfulness instructor will guide focused attention meditations that will last from 15 to 30 minutes. Participants will be instructed at the beginning of the intervention and will have audio files to guide the exercises during their practice.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical exercise
Description: An instructor will guide to running with mental association strategies that will last from 15 to 30 minutes. Participants will be instructed at the beginning of the intervention and will have audio files to guide the exercises during their practice.
Study: NCT05817565

Intervention type: DEVICE
Intervention: Ultrasound (Phyaction 190 I); with a frequency of 3 MHz was used
Description: Intermittent cervical traction (traction force equal 8% of body weight) was applied with the patient lying supine and the head in neutral position.
Study: NCT04969029

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirelizumab
Description: In the immunotherapy group, the treatment regimen was Tirelizumab 200mg, intravenously infused once every 3 weeks until the end of 12 months of treatment, with a total of 17 infused times.
Study: NCT06158334

Intervention type: DRUG
Intervention: Describe the respective haemostatic efficacy of Elocta® for haemopilia A during surgical procedures
Description: All surgical data will be collected: surgery, biology, administration of Elocta®, bleeding and transfusion, hemostatic efficacity, surgery complication and bleeding

Intervention type: DRUG
Intervention: Describe the respective haemostatic efficacy of Alprolix® for haemopilia B during surgical procedures
Description: All surgical data will be collected: surgery, biology, administration of Alprolix®, bleeding and transfusion, hemostatic efficacity, surgery complication and bleeding...
Study: NCT05071170

Intervention type: BEHAVIORAL
Intervention: Ad libitum energy intake
Description: Investigate post meal satiety and subsequent post meal energy intake according to degree of food processing and eating behaviour
Study: NCT05932108

Intervention type: BEHAVIORAL
Intervention: Education in TERMA
Description: Education of staff in TERMA. The primary aim of TERMA is to prevent aggression and violence through a system of low-effective treatment that is divided into escalating levels based on the patient's aggression level, risk of violence, and acts of violence . The TERMA model focuses on treatment, communication, and management of compassionate healthcare in forensic psychiatric settings . The levels of the TERMA model are in a cascading order, whereby if the treatment and management of one level are ineffective, the next level is initiated, and so on. The primary level involves the daily behavior and health status of the patient. The secondary level involves risk assessment and violence management, with a focus on creating an understanding of the situation for both the patient and healthcare workers. The tertiary level is utilized when violence cannot be avoided . Each level corresponds to a specific response according to the demands of the situation and environment.

Intervention type: OTHER
Intervention: Changed work routines based on TERMA
Description: NO planned intervention but staff work routines and behavior may change after their education in TERMA. Patients are exposed to these changes.
Study: NCT06032910

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical mesh
Description: Prophylactic synthetic non-absorbable keyhole mesh placement upon construction of ileal conduit.
Study: NCT04886323

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cold atmospheric plasma treatment device
Description: Treat with cold atmospheric plasma treatment device.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Itraconazole Capsules
Description: Treat with Itraconazole capsules
Study: NCT04748666

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Solving Training
Description: Problem Solving Training (PST) is a metacognitive strategy training approach, grounded in self-management theory, that teaches a simple, systematic method for evaluating problems, generating and selecting solutions, developing specific goals and action plans, and evaluating and revising plans as needed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Solving Training
Description: Problem Solving Training (PST) is a metacognitive strategy training approach, grounded in self-management theory, that teaches a simple, systematic method for evaluating problems, generating and selecting solutions, developing specific goals and action plans, and evaluating and revising plans as needed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Solving Training
Description: Problem Solving Training (PST) is a metacognitive strategy training approach, grounded in self-management theory, that teaches a simple, systematic method for evaluating problems, generating and selecting solutions, developing specific goals and action plans, and evaluating and revising plans as needed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Solving Training
Description: Problem Solving Training (PST) is a metacognitive strategy training approach, grounded in self-management theory, that teaches a simple, systematic method for evaluating problems, generating and selecting solutions, developing specific goals and action plans, and evaluating and revising plans as needed.
Study: NCT06034288

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xeomin 100 UNT Injection
Description: intravesical injection

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Botox 100 UNT Injection
Description: intravesical injection
Study: NCT01747512

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: C-PERT
Description: Patients with thyroid and Head and Neck cancer

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: G-PERT
Description: Patients with thyroid and Head and Neck cancer
Study: NCT05887986

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hand-held fan airflow stimulation
Description: Outcome dyspnea measures:~After the fan training application given to the hand-held fan airflow stimulation group by the researchers, the hand fan application will be made for 5 days. On the baseline, day 3, and day 5 of the study, the dyspnea level will be evaluated.~Outcome comfort measures:~After the fan training application given to the hand-held fan airflow stimulation group by the researchers, the hand fan application will be made for 5 days. On the baseline, day 3, and day 5 of the study, the comfort level of the patients will be evaluated.
Study: NCT04836585

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eMBC Intervention
Description: The treating psychiatrist sets a flag in the patient's electronic chart that prompts them to complete self-report scales prior to each appointment:~1. Edinburgh Postnatal Depression Scale (EPDS) for symptoms of depression and anxiety~2. PROMIS Neuro-QOL and PROMIS ASCQ-Me Social Functioning Short form for measures of functional capacity~3. Adapted Frequency, Intensity, and Burden Side Effects Rating (FIBSER) Scale for participants taking antidepressant medication to measure side effects~Patient participants and providers can view the questionnaire results over time in the electronic chart item by item, and/or see them in graphical format. During the clinical encounter, the provider and patient participant review the results of the scales, as part of a collaborative re-evaluation of the treatment plan.
Study: NCT05966649

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Synbiotics
Description: Oral synbiotic (food supplement) containing 8 probiotic Lactobacillus strains, the prebiotics inulin, fructooligosaccharides (FOS) and D-mannose.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo