TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04772222

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine Hydrochloride
Description: Potent α2-adrenergic receptor agonist that provides sedation, analgesia, and prevents shivering but does not suppress ventilation.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine Sulfate
Description: Opioid agonist that provides analgesia, pain management and sedation and may suppress ventilation.
Study: NCT06799286

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986489
Description: Specified dose on specified days
Study: NCT06796062

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: One capsule (1 mg, 20 mg, or 30 mg) administered once orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: One capsule (1 mg, 20 mg, or 30 mg) administered once orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: One capsule (1 mg, 20 mg, or 30 mg) administered once orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: One capsule (1 mg, 20 mg, or 30 mg) administered once orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: One capsule (1 mg, 20 mg, or 30 mg) administered once orally
Study: NCT06799962

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enhanced Body-Swap for Anorexia Nervosa
Description: The protocol begins with a baseline session, where participants familiarize themselves with their virtual body and provide anamnesis and therapeutic efficacy baseline data. The treatment phase includes 12 bi-weekly sessions where participants embody a virtual avatar in a VR environment. During each session, the Body Mass Index (BMI) of the virtual body is incrementally increased toward a target BMI approximating normal weight (18.5). Follow-ups are conducted at 4, 8, and 12 weeks to assess long-term effects.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Emotional Rescripting for Bulimia Nervosa
Description: The protocol starts with an assessment phase (1 session), gathering anamnesis and baseline therapeutic efficacy data. This is followed by an evaluation phase (2 sessions), where participants rate craving responses for virtual foods and environments in immersive VR, with physiological data collected via biosensors. Using this data, a personalized exposure hierarchy is created, combining the most craving-inducing foods and environments into 40 interactive 3D scenarios. The treatment phase involves 9 VR sessions focusing on emotional regulation and craving management. Follow-ups at 4, 8, and 12 weeks evaluate progress.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard Therapy for Anorexia Nervosa (Control)
Description: Participants follow a similar structure with a baseline session to collect anamnesis and baseline data, but without VR immersion. The treatment phase consists of 12 bi-weekly sessions of standard cognitive-behavioral therapy (CBT), focusing on addressing maladaptive thought patterns, promoting healthy eating behaviors, and reducing body image disturbances. Follow-ups are conducted at 4, 8, and 12 weeks to monitor progress. No VR or AI technologies are integrated.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard Therapy for Bulimia Nervosa (Control)
Description: Participants undergo an assessment phase (1 session) to collect baseline data and an evaluation phase (2 sessions) using standard craving questionnaires without VR immersion or biosensors. The treatment phase includes 9 sessions of traditional CBT targeting binge-purge cycles and emotional triggers. Follow-ups at 4, 8, and 12 weeks monitor progress without the integration of VR or AI technologies.
Study: NCT06799429

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supervised in-person group
Description: Individually prescribed and directed/supervised by a fitness trainer in-person, multi-mode exercise 2 x a week for 30-60 minutes The fitness trainer is with the participant while they exercise.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Monitored distance group
Description: Individually prescribed ulti-mode exercise 2 x a week for 30-60 minutes. Written plan/feedback and support by phone/text or email is provided by a fitness trainer who is not present with the participant when they exercise.
Study: NCT06798662

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound-Guided Pulsed Radiofrequency (PRF)
Description: A high-frequency linear ultrasound transducer will be used for this procedure. The transducer will be placed transversely over the target rib area to obtain a clear visualization of the rib, intercostal muscles, and pleura. The entry point for needle insertion will be selected 1-2 cm inferior to the inferior border of the target rib. Using a 22G radiofrequency (RF) needle, an in-plane approach will be used for needle advancement. The needle will be advanced slowly until it reaches the inferior border of the rib. The needle will then be withdrawn 1-2 mm to ensure the needle tip is positioned adjacent to the intercostal nerve. The RF needle will then be connected to the RF generator for sensory testing. Stimulation parameters will be set at 50 Hz and 0.5-1V. The target location will be considered accurate if stimulation induces pain in the participant. Pulsed radiofrequency treatment will then be administered using the following parameters: voltage of 45V, frequency of 2 Hz, pulse width
Study: NCT05761106

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oculomotor Therapy
Description: It will consist exercise of a convergence technique and an accommodative technique.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oculomotor Therapy
Description: It will consist exercise of a convergence technique and an accommodative technique.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapy for Temporomandibular Disorder
Description: It will consist exercise of a ATM and cervical spine.
Study: NCT05465018

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Worst case hardware
Description: To test if software still works with an older smartphone

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Damaged lens
Description: To test if software is still working when the lens of the smartphone is damaged

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Face or chest outside test frame
Description: To test software if the participants face or chest is outside the test frame
Study: NCT05607511

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Probiotics baby immunity formula (SIM03)
Description: Daily oral intake of a probiotics sachet
Study: NCT05359874

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab-IRDye800CW
Description: In order to be able to detect this marker in vivo, special multispectral fluorescence-reflecting cameras (MFRI) were developed, which can be used for the intraoperative display of the tumor and potentially affected lymph nodes and which are now to be evaluated together with the fluorescence marker.
Study: NCT05096247

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure
Description: This device is an RF device.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure
Description: This device is an RF device.
Study: NCT06799091

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Low frequency TENS
Description: Low TENS group participated in twelve sessions of electrical stimulation with low frequency (TENS, 10 Hz/200 μs) was applied with self-adhesive electrodes (size 9 × 5 cm,), in the paravertebral ganglionar region (from T1 to L2). The sessions took place at the same time of the day, lasted 30 min, in an acclimatized room (23 °C) and the intensity of the current was delivered at sensory-level intensity, adjusted every 5 min by the sensory threshold, during the 30 min as tolerated by each subject, but without motor contraction or pain reported by the subject.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Low frequency TENS
Description: Low TENS group participated in twelve sessions of electrical stimulation with low frequency (TENS, 10 Hz/200 μs) was applied with self-adhesive electrodes (size 9 × 5 cm,), in the paravertebral ganglionar region (from T1 to L2). The sessions took place at the same time of the day, lasted 30 min, in an acclimatized room (23 °C) and the intensity of the current was delivered at sensory-level intensity, adjusted every 5 min by the sensory threshold, during the 30 min as tolerated by each subject, but without motor contraction or pain reported by the subject.
Study: NCT06798480

Intervention type: OTHER
Intervention: Self-administered survey
Description: An anonymous self-administered online questionnaire hosted on LimeSurvey, lasting approximately 20 minutes, will be completed by participants. A panel of participants representative of the general population will be provided by the Selvitys Institute. In parallel, the self-administered questionnaire will also be distributed via posts on social media platforms (Facebook, YouTube, Instagram, TikTok, Snapchat, and X) over a period of three months.
Study: NCT06793891

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ashwagandha root
Description: This substance is extracted from the root of the plant.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ashwagandha root and leaf
Description: This substance is extracted from both the root and leaves of the plant.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: The inert placebo does not contain any of the plant matter.
Study: NCT06797986

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BVAC-E6E7 (low level)
Description: BVAC-E6E7 is an immunotherapeutic vaccine designed to treat unresectable recurrent or metastatic head and neck squamous cell carcinoma positive to HPV 16 or 18.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BVAC-E6E7 (high level)
Description: BVAC-E6E7 is an immunotherapeutic vaccine designed to treat unresectable recurrent or metastatic head and neck squamous cell carcinoma positive to HPV 16 or 18.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BVAC-E6E7 (RP2D)
Description: BVAC-E6E7 is an immunotherapeutic vaccine designed to treat unresectable recurrent or metastatic head and neck squamous cell carcinoma positive to HPV 16 or 18.
Study: NCT06798896

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPN-817
Description: SPN-817 starting at 0.25 mg bid up to 4.00 mg bid

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo, bid
Study: NCT05096247

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Icon
Description: This device works with IPL (Intense Pulsed Light) handpieces.
Study: NCT05047939

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: remimazolam-based TIVA
Description: In the remimazolam-based TIVA group, general anesthesia is induced and maintained with a continuous infusion of remimazolam using an infusion pump. In the remimazolam group, its antagonist, flumazenil, is administered at the end of surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: propofol-based TIVA
Description: In the propofol-based TIVA group, general anesthesia is induced and maintained with a target-controlled infusion of propofol using an infusion pump (Orchestra®; Fresenius Vial, France).
Study: NCT06800196

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KNT-0916
Description: • KNT-0916 is an oral inhibitor of FGFR2.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KNT-0916
Description: • KNT-0916 is an oral inhibitor of FGFR2.
Study: NCT06798558

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lu-17-PSMA-617
Description: Lu-17-PSMA-617 administration
Study: NCT06318078

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eCHIS
Description: The electronic Community health Information System (eCHIS) is a Government of Uganda owned application used by community health workers for quality health assessments and improved reporting. The eCHIS intervention allows for the registration of longitudinal profiles for client centered care as well as provides care guidance to aid decision making. For its users, the app has a task tab for schedule management and dashboards for performance help management and impact tracking by supervisors. This app is interoperable with national reporting tools such as DHIS2. The app has ten workflows including registration of households and new persons, death reporting, iCCM assessment, treatment and referral follow up, stock monitoring, data synchronization, pregnancy registration, ANC danger signs and follow up, family planning registration, and screening (tuberculosis, hypertension, sickle cell, tobacco use and net use).
Study: NCT05295901

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mKOAH application
Description: mobile app installed group
Study: NCT06454383

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diagnostic Imaging
Description: Undergo imaging scans
Study: NCT04717557

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyperbaric Oxygen
Description: Hyperbaric oxygen (HBO2) 1-2 times daily for up to 10 times after amputation
Study: NCT06454383

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Given IV
Study: NCT06798389

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse Nudge
Description: Nurses will be nudged to call the patients, which may increase the likelihood that the patient receives a post-appointment follow-up call.
Study: NCT06798792

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PechaKucha technique
Description: The Discharge Education course was taught using the PechaKucha technique.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TeachBack technique
Description: The Discharge Education course was taught using the TeachBack technique.
Study: NCT06800092

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sildenafil
Description: Sildenafil, 50mg, daily
Study: NCT06799104

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pyramidal training
Description: Pyramidal training prescription:Mode of exercise: aerobic interval training. Intensity: ranging from 20-80% from THR. Duration: 40 minutes per session.Frequency: Three sessions per week for 12 weeks.~The course of the program will be 2 sets of pyramidal training with 10 minutes for rest between them. Each set will be 5 levels of incremental and 5 levels of decremental aerobic exercise and each level 2 minutes on a treadmill.~1. Level one: will be set as a 20% walking of Karvonen formula.~2. Level two: will be set as a 30% running of Karvonen formula.~3. Level three: will be set as a 50%running of Karvonen formula.~4. Level four: will be set as a 70% running of Karvonen formula.~5. Level five: will be set as a 80% running of Karvonen formula.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mediterranean diet
Description: Mediterranean diet:~Meal Composition Main meals consumed daily should be a combination of three elements: cereals, vegetables and fruits, and a small quantity of legumes, beans or other (though not in every meal). Cereals in the form of bread, pasta, rice, couscous or bulgur (cracked wheat) should be consumed as one-two servings per meal. Vegetable consumption should amount to two or more servings per day, in raw form for at least one of the two main meals (lunch and dinner). Fruit should be considered as the primary form of dessert, with one-two servings per meal.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: Mediterranean diet:~Meal Composition Main meals consumed daily should be a combination of three elements: cereals, vegetables and fruits, and a small quantity of legumes, beans or other (though not in every meal). Cereals in the form of bread, pasta, rice, couscous or bulgur (cracked wheat) should be consumed as one-two servings per meal. Vegetable consumption should amount to two or more servings per day, in raw form for at least one of the two main meals (lunch and dinner). Fruit should be considered as the primary form of dessert, with one-two servings per meal.
Study: NCT06798701

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Undergo standard care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Use VR device
Study: NCT06798272

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: dialysisis with and without glucose in the dialysis
Description: there were assessed three consecutive hemodialysis sessions
Study: NCT06798025

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Punctal dilation
Description: Patients were treated with punctal dilatation only.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Punctal dilation and topical medication
Description: Patients were treated with a combination of punctal dilation and topical medication in the form of preservative-free steroid eye drops based on dexamethasone sodium phosphate (0.1%) and preservative-free artificial tears based on sodium hyaluronate, polyethylene, and propylene Glycol.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone acetonide
Description: Patients were treated with a peri-punctual injection of Triamcinolone acetonide.
Study: NCT06799234

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1 RVF
Description: One 0.5mL dose contains 5x10\^10vp ChAdOx1 RVF.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1 RVF
Description: One 0.5mL dose contains 5x10\^10vp ChAdOx1 RVF.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Rabies Vaccine
Description: 0.5mL per dose

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rabies Vaccine
Description: 0.5mL per dose
Study: NCT06799624

Intervention type: OTHER
Intervention: Observation only
Description: Only observation following standard of care (histological diagnosis, molecular classification, progestine therapy)
Study: NCT06799416

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ARGX-109
Description: administrations of ARGX-109

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: administrations of placebo comparator
Study: NCT06798246

Intervention type: DRUG
Intervention: Chemotherapy
Description: Gemicitabin and cisplatin

Intervention type: DRUG
Intervention: Immunotherapy
Description: PD-1/PD-L1

Intervention type: DRUG
Intervention: ADC
Description: ADC drug like RC48

Intervention type: DRUG
Intervention: Chemotherapy combined with immunotherapy
Description: Chemotherapy combined with immunotherapy
Study: NCT05407129

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family safety reporting intervention
Description: Family safety reporting intervention for patients/families
Study: NCT06800144

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Heart rate synchronized motor imagery music therapy
Description: Participants included in this group will listen a metronome sound in a rhythm synchronized with their heart rate.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Heart rate synchronized music therapy
Description: Participants included in this group will listen to soothing/relaxing music without lyrics in a rhythm synchronized with their heart rate.
Study: NCT06800001

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Physical Activity is an 8-week practical intervention for managing the stereotyped behavior \& anxiety. Week 1: Introduction - Build engagement with the help of rapport building. Learn \& practice ball-tapping exercise with warm up \& cool down relaxation exercise. Week 2: Calmness- Practice jumping in trampoline exercise and learn balloon breathing exercise that give calmness. Week 3: Focus enhancement-Learn skills of jumping exercise to increase focus and improve impulse. Week 4: Strength, balance, and stress relief -explore the gym ball exercise in different directions that improves emotional regulation. Week 5: self control - Learn strategies for specific jumping patterns that improves impulse control and focus in children with ASD. Week 6: Reduce Stereotyped Behaviors - Learn complex trampoline exercises. Week 7: Skill Reinforcement- Review exercises, increasing speed or direction changes. Week 8: Integration -Encourage playful interaction to maintain engagement \& consolidate skills.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Activity
Description: Physical Activity is an 8-week practical intervention for managing the stereotyped behavior \& anxiety. Week 1: Introduction - Build engagement with the help of rapport building. Learn \& practice ball-tapping exercise with warm up \& cool down relaxation exercise. Week 2: Calmness- Practice jumping in trampoline exercise and learn balloon breathing exercise that give calmness. Week 3: Focus enhancement-Learn skills of jumping exercise to increase focus and improve impulse. Week 4: Strength, balance, and stress relief -explore the gym ball exercise in different directions that improves emotional regulation. Week 5: self control - Learn strategies for specific jumping patterns that improves impulse control and focus in children with ASD. Week 6: Reduce Stereotyped Behaviors - Learn complex trampoline exercises. Week 7: Skill Reinforcement- Review exercises, increasing speed or direction changes. Week 8: Integration -Encourage playful interaction to maintain engagement \& consolidate skills.
Study: NCT06800040

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Memory training
Description: Memory training
Study: NCT06798467

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Endodontic sealer
Description: endodontic sealer is a material used in root canal therapy to fill the microscopic spaces between the root canal filling material (typically gutta-percha) and the walls of the root canal. Its primary function is to create a tight seal that prevents the ingress of bacteria and fluids into the root canal system, helping to prevent reinfection and promoting the healing of periapical tissues. Endodontic sealers also help to ensure that the root canal filling reaches all parts of the canal, especially in complex or irregularly shaped anatomies.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: post obturation pain
Description: Unpleasant sensation of any degree of pain after root canal treatment.