TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04855357

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resident counselling
Description: One hour, one-on-one counseling for residents

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Staff Training
Description: A two-hour training for PSH staff on how to provide referrals to smoking cessation programs using materials previously developed from UCSF's 'Rx for change' curriculum for service providers, directed toward empowering PSH staff to provide referrals to local cessation services using the ask, advise, and refer approach. The training will address nicotine addiction, tobacco use among PSH residents, pilot data, brief cessation counseling (ask, advise, and refer), and local resources for cessation. Because PSH resident-PSH staff encounters will take place as part of routine care, the study team will request permission from a random sample of staff and resident dyads (n=40) to record these interactions to assess fidelity.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Staff Training
Description: A two-hour training for PSH staff on how to provide referrals to smoking cessation programs using materials previously developed from UCSF's 'Rx for change' curriculum for service providers, directed toward empowering PSH staff to provide referrals to local cessation services using the ask, advise, and refer approach. The training will address nicotine addiction, tobacco use among PSH residents, pilot data, brief cessation counseling (ask, advise, and refer), and local resources for cessation. Because PSH resident-PSH staff encounters will take place as part of routine care, the study team will request permission from a random sample of staff and resident dyads (n=40) to record these interactions to assess fidelity.
Study: NCT05684705

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BV100
Description: Intravenous infusion
Study: NCT05167409

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Evorpacept (ALX148)
Description: IV QW

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: IV QW

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV Q3W
Study: NCT06100172

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN)
Description: This method of simultaneous vagal and trigeminal stimulation via the external ear is known as transcutaneous auricular neurostimulation (tAN), as the targets of electrical stimulation include the auricular branch of the vagus nerve (ABVN) and auriculotemporal nerve (ATN), which is a branch of the mandibular division of the trigeminal nerve. Electrodes applied to select dermatome regions can target ear neural structures and deliver non-invasive vagus nerve stimulation (VNS) and trigeminal nerve stimulation (TNS). Use of tAN for pain relief is an attractive alternative to pharmacologic and opioid-based approaches because it is safe and effective and presents no addiction liability.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham Control Device
Description: This device looks like the active device, but no stimulation will be delivered.
Study: NCT06514430

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phenazopyridine
Description: 200mg PO Phenazopyridine taken prior to the Botox® injection procedure as an analgesic.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 1% lidocaine with sodium bicarbonate
Description: 50cc of 1% lidocaine with 50cc sodium bicarbonate injected into the bladder lumen prior to the Botox® injection procedure.
Study: NCT05813548

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FASTer Way Intervention
Description: 6-weeks of exercise, building healthy nutritional habits such as intermittent fasting and carb-cycling
Study: NCT05797714

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tenofovir Amibufenamide（TMF）
Description: TMF, 25mg QD, from baseline to 144 weeks
Study: NCT05695326

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 3D printing technology learning program
Description: The study is aimed to evaluate a 3D printing technology learning program for rehabilitation professionals
Study: NCT05813548

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group Intervention
Description: 6-weeks of following general exercise and nutrition guidelines from American Heart Association (AHA) and United States Department of Agriculture (USDA), respectively.
Study: NCT05289518

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Remote ischemic conditioning (RIC)
Description: RIC is a non-invasive therapy which is performed by automated pneumatic cuffs placed on bilateral arms. The RIC protocol include five cycles of 5-min inflation to 220mmHg and 5-min deflation.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham remote ischemic conditioning (Sham-RIC)
Description: The Sham-RIC protocol include five cycles of 5-min inflation to 60 mmHg and 5-min deflation by placing automated pneumatic cuffs on bilateral arms.
Study: NCT05132114

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Lugol's iodine test
Description: Intraoperative application of Lugol's iodine (i.e. staining of the cervix with Lugol's iodine solution)
Study: NCT06053125

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adipose Tissue Biopsy
Description: Fat sample collected from abdomen before exercise, immediately after exercise, and 3 hours after exercise

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adipose Tissue Biopsy
Description: Fat sample collected from abdomen before exercise, immediately after exercise, and 3 hours after exercise

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adipose Tissue Biopsy
Description: Fat sample collected from abdomen before exercise, immediately after exercise, and 3 hours after exercise

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adipose Tissue Biopsy
Description: Fat sample collected from abdomen before exercise, immediately after exercise, and 3 hours after exercise

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 30 minutes of exercise on a cycle ergometer exercise machine

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 30 minutes of exercise on a cycle ergometer exercise machine

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 30 minutes of exercise on a cycle ergometer exercise machine

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 30 minutes of exercise on a cycle ergometer exercise machine
Study: NCT05011201

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual Joint Visual Feedback without Scoring
Description: Participants will walk on the treadmill while given instantaneous anterior and posterior foot position and immediate scoring information using the DJVF interface. A pediatric physical therapist will provide (1) verbal encouragement and redirection of attention to the task as needed (2) verbal cueing to assist if difficulty in interpreting the feedback and appropriate modification is noted.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual Joint Visual Feedback with Scoring
Description: Participants will walk on the treadmill using the same DJFB with additional visual cumulative scoring on their performance. A pediatric physical therapist will provide (1) verbal encouragement and redirection of attention to the task as needed (2) verbal cueing to assist if difficulty in interpreting the feedback and appropriate modification is noted.
Study: NCT04864587

Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence used for image recognition in pouchoscopy
Description: The aim of this study is to develop an image recognition algorithm that reliably detects the different graduations of pouch inflammation and neoplasms in the pouch
Study: NCT04709133

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: multi-ligament knee surgery
Description: a chart review will be performed to identify patients who underwent surgical treatment for multi-ligamentous knee injuries at Assiut University Hospital performed by one of sports medicine orthopaedic surgeons at Assiut arthroscopy and sport unit.
Study: NCT06166121

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ShenJu
Description: One package per time, twice a day, 90 days of treatment

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One package per time, twice a day, 90 days of treatment (the placebo was basically the same as ShenJu in terms of appearance, shape, color, taste, etc.)
Study: NCT04135170

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: ALBC vs plain bone cement
Description: The patients undergoing full-cemented primary total knee arthroplasty are allocated to either ALBC or plain bone cement and compare the effectiveness of ALBC use vs pain bone cement bone cement without antibiotic) with respect to revision due to PJI one year after primary TKA surgery.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ALBC vs plain bone cement
Description: The patients undergoing full-cemented primary total knee arthroplasty are allocated to either ALBC or plain bone cement and compare the effectiveness of ALBC use vs pain bone cement bone cement without antibiotic) with respect to revision due to PJI one year after primary TKA surgery.
Study: NCT05172583

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The control groups will receive the nursing interventions that are performed daily in the adult ICU. These are orientation in time, space, and place, accompaniment of the family for two hours in the morning and two hours in the afternoon, physical therapy once a day according to the patient's condition, medication with conscious sedation, and progressive reduction analgesics. opioids and benzodiazepines.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interventions to reduce delirium based on DSM and scientific evidence
Description: The interventions are designed from the structure of the Dynamic Symptoms Model (DSM), taking into account the antecedents of delirium, physiological such as the medical condition of mechanical ventilation and pain, and drug treatment with sedatives and analgesics; the psychological, social, and spiritual antecedents with stimulation in the values, life experience, personality and spirituality, and the environmental antecedents with an adaptation of the physical conditions of the ICU. In addition, previous experience with identification and care of concomitant symptoms such as fear, confusion, restlessness, loneliness, and discomfort, and with the measurement and classification of the trajectory of delirium when it occurs, will also be considered. The interventions follow the scientific evidence, mainly from the ABCDEF bundle. All interventions are non-pharmacological.
Study: NCT05380271

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sequential DEB-BACE and Arotinib and Tirelizumab
Description: DEB-BACE+Arotinib + Tirelizumab

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DEB-BACE alone
Description: DEB-BACE alone
Study: NCT04867252

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Resveratrol (1000mg twice a day), Myoinositol 1000mg (Twice a day)
Description: 51 Patients with PCOS receiving Resveratrol and Myoinositol 1000mg and 1000mg BD daily respectively

Intervention type: DRUG
Group type: OTHER
Intervention: Metformin (500 mg Twice a day), Pioglitazone (15 mg Twice a day)
Description: 51 Patients with PCOS receiving Metformin and Pioglitazone 500 mg and 15 mg BD daily respectively
Study: NCT06213688

Intervention type: OTHER
Group type: OTHER
Intervention: blood sampling
Description: blood sampling at inclusion

Intervention type: OTHER
Group type: OTHER
Intervention: blood sampling
Description: blood sampling at inclusion

Intervention type: OTHER
Group type: OTHER
Intervention: urine sampling
Description: urine sampling at inclusion

Intervention type: OTHER
Group type: OTHER
Intervention: urine sampling
Description: urine sampling at inclusion
Study: NCT05306470

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ethyl chloride
Description: Application of ethyl chloride for a cooling effect to numb the area for oral infiltration anesthetic

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 5% lidocaine gel
Description: Application of 5% lidocaine gel to numb the area for oral infiltration anesthetic
Study: NCT04836000

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In addition to the conservative treatment, Low-level laser therapy
Description: For Experimental Group A Gallium-aluminum-arsenide (Ga-Al-As) diode laser instrument (Roland Serie, Elettronica Pagani, Paderno, Italy, Mod IR 27/1) will be used (wavelength 904 nm, 5500 Hz frequency, 27 W maximum power output per pulse, 13.2 mW average power, 0.8-cm2 spot size, 1.6 J of total energy will be delivered per point at each session at a power density of 16.5 mW/cm2, and the cumulative energy per point for all sessions was 16 J).~Ga-Al-As laser therapy will be applied to experimental group patients two times per week for 6 weeks in 10-min sessions. LLLT will be applied over the tuberculum majus and minus, the anterior and posterior faces of the capsule, and the subacromial regions. Each point will be treated for 120 sec. The head of the instrument will be held perpendicular to the body surface and in skin contact without pressure.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: In addition to the conservative treatment, Low-level laser therapy (turned off)
Description: For Placebo Group In the placebo group, laser instrument will be applied in the same way but the device will be turned off during treatment sessions. Patients and physiotherapist will be asked to use protective eyeglasses during therapy for safety.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative treatment solely
Description: For Control Group All patients using an immobilization bandage up to post-operative 6th week will receive the standardized 6-week supervised rehabilitation program advocated by the same physiotherapist (CK), 7 years of experience in the clinical treatment of rotator cuff tear, after the baseline assessment. Composed of 30 treatment sessions (five days/week) of 45 to 60 minutes, the rehabilitation program will be provided individually to all participants. Physiotherapy sessions will be devoted to strength, mobilizations, stretching, perturbation, and sensorimotor training using motor control exercises, hence, to restore adequate shoulder neuromuscular control. The treatment program will also be included patient education.
Study: NCT06250010

Intervention type: DIAGNOSTIC_TEST
Intervention: tissue samples (healthy and tumor taken from the same patient) and tissue samples (decidualized endometrium and trophoblast taken from it patient)
Description: Correlation between the immuno-score results of each patient with his prognosis, in terms disease-free survival, overall survival, relapse-free survival, disease-specific survival cancer, distant and/or local free survival, to validate their potential role independent in the progression of endometrial cancer; later, for a better characterization of the various ones risk classes, we will combine our immuno-score with the already known risk factors, included in the ESMO-ESGO-ESTRO classification and in the biomolecular classification of endometrial cancer, to investigate whether the Microenvironmental immunological factors in endometrial cancer could allow better stratification of patients in risk classes.

Intervention type: DIAGNOSTIC_TEST
Intervention: tissue samples (healthy and tumor taken from the same patient) and tissue samples (decidualized endometrium and trophoblast taken from it patient)
Description: Correlation between the immuno-score results of each patient with his prognosis, in terms disease-free survival, overall survival, relapse-free survival, disease-specific survival cancer, distant and/or local free survival, to validate their potential role independent in the progression of endometrial cancer; later, for a better characterization of the various ones risk classes, we will combine our immuno-score with the already known risk factors, included in the ESMO-ESGO-ESTRO classification and in the biomolecular classification of endometrial cancer, to investigate whether the Microenvironmental immunological factors in endometrial cancer could allow better stratification of patients in risk classes.
Study: NCT05009901

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alpha Lipoic Acid 600 MG Oral Tablet
Description: Alpha lipoic acid 600 mg daily for 8 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo one tablet daily for 8 weeks
Study: NCT05203250

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.

Intervention type: RADIATION
Intervention: Heavy-ion therapy (hadrontherapy)
Description: Only data available from routine clinical practice at the National Center for Oncological Hadrontherapy (CNAO), based Pavia, will be collected. Intervention is not assigned.
Study: NCT05442710

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ARTICE
Description: Extracorporal treatment with purified granulocyte concentrate
Study: NCT04688203

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium Sulfate Injection
Description: will receive IV bolus dose of 40mg/kg magnesium sulfate in 100 ml saline solution over ten minutes then continuous infusion of 10-15mg/kg/h will be titrated till achieve target mean arterial blood pressure (55-65 mmHg) and will be terminated by the end of surgery.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Labetalol Injectable Solution
Description: will receive IV bolus does of labetalol 0.25 mg/kg over ten minutes then continuous infusion of 0.5-1mg/kg/h will be titrated till achieve target mean arterial blood pressure (55-65 mmHg) and will be terminated by the end of surgery.
Study: NCT06403930

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary Obturator
Description: Maxillary obturators are prosthetic devices used to close maxillary defects resulting from surgical removal of part or all of the maxilla bone due to conditions like tumors or congenital anomalies. They separate the oral and nasal cavities, restore speech, swallowing, and mastication functions, provide facial support, and improve aesthetics and quality of life.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Maxillary Obturator
Description: Maxillary obturators are prosthetic devices used to close maxillary defects resulting from surgical removal of part or all of the maxilla bone due to conditions like tumors or congenital anomalies. They separate the oral and nasal cavities, restore speech, swallowing, and mastication functions, provide facial support, and improve aesthetics and quality of life.
Study: NCT06427057

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab plus chemotherapy
Description: AK104 (10mg/kg ,Q3W，intravenously) plus chemotherapy（e.g. gemcitabine or albumin paclitaxel，dosage based on guidelines or instructions）

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab plus TKI
Description: Patients will receive AK104 (10mg/kg ,Q3W，intravenously) plus TKI（e.g. sunitinib, pezopanib，dosage based on guidelines or instructions)
Study: NCT04734288

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vit.D3 5000 IU, Immune Active
Description: The subjects will receive monthly (for either 3 or 6 months):~1. Vit.D3 5000 and Immune Active. The first phase includes 3 months of treatment and the second phase includes 6 months of treatment.~2. An in-home Vit.D/ hs-CRP test kit and asked to self-administer a blood collection via fingerstick and return the kits for analysis within a few days.~3. Two online questionnaires each month and asked to fill them out within a few days. It will either be the Medical Outcomes Study (MOS) Short Form (SF)-36 and the Health Status Baseline or Health Status Follow-up Questionnaire.
Study: NCT06373705

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cardiac simulator
Description: A computer software cardiac simulator for surgical planning in complex Congenital Heart Disease (CHD) pediatric patients.
Study: NCT05394038

Intervention type: OTHER
Intervention: None，observational study.
Description: observational study
Study: NCT06025136

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Using a gel pillow
Description: Within the scope of the study, gel pillows with a cold surface were used in the patients in the study group. It is produced by combining the obtained special liquid with elastic material with NASA approved molecule exchange technology and is made of OEKO-TEX CLASS 1 certified material.Thanks to the gel material on the pillow surface, the surface temperature is reduced from 37°C to 24°C in about 10 seconds. It gives a feeling of coolness with its thermal conductivity feature.