TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05598905

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pregabalin 150mg
Description: one capsule of 150mg 90 minutes after 10mg of oxycodone

Intervention type: DRUG
Group type: OTHER
Intervention: Oxycodone 10mg
Description: one 10mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone 10mg
Description: one 10mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone 10mg
Description: one 10mg tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacosamide 150 mg
Description: one capsule of 150mg 90 minutes after 10mg of oxycodone
Study: NCT05270148

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HIIT
Description: 12 weeks training High-Intensity Interval Training consists of 3 sessions per week in a cycle ergometer, with 1-2days off between sessions, under the supervision of a personal trainer. HIIT program will consist of 3-5 series of 1 min duration at 90-130% of its maximum power (determined in the first training session), with 90 seconds of rest between sets (estimated total time of the session: 10 minutes).Depending on the number of training session, the loadand the series will increase up to 40% more than the maximum load.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fat Max
Description: 12 weeks training Fatmax consist in 3 sessions per week in a cycle ergometer, with 1-2days off between sessions, under the supervision of a personal trainer. MICTprogram will consist of sessions of approximately ˜45min of moderate aerobic exercise (at the intensity at which the maximal fat oxidation was achieved in the laboratory test) in cycle ergometer.
Study: NCT05370027

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Auricular Vagus Nerve Stimulation
Description: Vagus nerve stimulation will be applied with the Vagustim device for 20 (10+10) minutes, with a biphasic frequency, a frequency of 10 Hz, a pulse width of 300 μs in Modulation mode, and a constant current intensity where the participant feels the current comfortably.
Study: NCT05839847

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-intensity focused ultrasound
Description: A noninvasive brain stimulation device using low-intensity focused ultrasound (LIFU) - ultrasound will be used to test whether noninvasive brain stimulation can reduce reactions to sensory stimuli.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-intensity focused ultrasound
Description: A noninvasive brain stimulation device using low-intensity focused ultrasound (LIFU) - ultrasound will be used to test whether noninvasive brain stimulation can reduce reactions to sensory stimuli.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-intensity focused ultrasound - sham
Description: A sham condition that will mimic the application of LIFU without actually administering any ultrasound to the brain.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-intensity focused ultrasound - sham
Description: A sham condition that will mimic the application of LIFU without actually administering any ultrasound to the brain.
Study: NCT04774614

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: anterior laminate veneers
Description: VITA ENAMIC multiColor

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: anterior laminate veneers
Description: VITA ENAMIC multiColor
Study: NCT04975672

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofuncional Therapy
Description: Group 1, with myofunctional therapy and SN1 functional orthopedic appliances The participant underwent a myofunctional therapy session every month, for 9 months. In this group, a series of procedures and techniques are carried out to create and mechanize muscular and orofacial patterns at rest and in function, eliminate habits, correct muscular imbalance, improve the aesthetics of the patient and normalize the functions of the stomatognathic system. The myofunctional therapy performed will be by an expert speech therapist

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofuncional Therapy
Description: Group 1, with myofunctional therapy and SN1 functional orthopedic appliances The participant underwent a myofunctional therapy session every month, for 9 months. In this group, a series of procedures and techniques are carried out to create and mechanize muscular and orofacial patterns at rest and in function, eliminate habits, correct muscular imbalance, improve the aesthetics of the patient and normalize the functions of the stomatognathic system. The myofunctional therapy performed will be by an expert speech therapist
Study: NCT05520918

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: the LIT test
Description: The retained functional capacity of leukocytes (primarily neutrophils) to produce ROS in response to PMA in whole blood samples could provide a rapid 10-minute detection method for objectively determining onset or occurrence of severe COVID-19 and monitoring progression and treatment of COVID-19.
Study: NCT05855395

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucocorticoid
Description: standard of care combined with glucocorticoid(dexamethasone: 3mg qd x 5 days; or prednisone: 20mg qd x 5 days; or methylprednisolone: 16mg qd x 5 days)
Study: NCT05370027

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Auricular Vagus Nerve Stimulation
Description: Vagus nerve stimulation will be applied with the Vagustim device for 20 (10+10) minutes, with a biphasic frequency, a frequency of 10 Hz, a pulse width of 300 μs in Modulation mode, and a constant current intensity where the participant feels the current comfortably.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Auricular Vagus Nerve Stimulation
Description: Vagus nerve stimulation will be applied with the Vagustim device for 20 (10+10) minutes, with a biphasic frequency, a frequency of 10 Hz, a pulse width of 300 μs in Modulation mode, and a constant current intensity where the participant feels the current comfortably.
Study: NCT06040307

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SPI (Surgical Pleth Index)
Description: Elective surgery in patients having trauma and orthopedic surgery with a combination of general and regional anesthesia. Opioid titration is guided by SPI during general anesthesia in the experimental arm.
Study: NCT06006442

Intervention type: BEHAVIORAL
Intervention: Vaping
Description: Subjects will be smoking the vapnig products that they admitted to using at baseline in the personal life prior to this study
Study: NCT04896307

Intervention type: OTHER
Intervention: Survey
Description: Survey
Study: NCT05859360

Intervention type: OTHER
Intervention: Physical performance and cardiovascular health measures
Description: * Retinal vessel analysis~* Muscle ultrasound~* Knee extension~* Voluntary activation~* spiroergometry

Intervention type: OTHER
Intervention: Physical performance and cardiovascular health measures
Description: * Retinal vessel analysis~* Muscle ultrasound~* Knee extension~* Voluntary activation~* spiroergometry

Intervention type: OTHER
Intervention: Physical performance and cardiovascular health measures
Description: * Retinal vessel analysis~* Muscle ultrasound~* Knee extension~* Voluntary activation~* spiroergometry

Intervention type: OTHER
Intervention: Physical performance and cardiovascular health measures
Description: * Retinal vessel analysis~* Muscle ultrasound~* Knee extension~* Voluntary activation~* spiroergometry
Study: NCT05553912

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: QBSafe
Description: an intervention comprised of (a) a set of conversation cards (QBSafe ASK) designed to enable patients to identify aspects of life with diabetes important to them and to share them with their clinician to obtain their input; and (b) materials that help clinicians respond to patient concerns.
Study: NCT05846867

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK119
Description: AK119 IV every 2 weeks.intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: AK112 IV every 2 weeks.intravenous infusion
Study: NCT06151860

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Static stretching
Description: Stretching exercises performed by maintaining the point of muscular discomfort without changing position for a certain period of time.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates stretching
Description: Stretching exercises performed dynamically, following the six basic principles of Pilates: concentration, control, center, precision, breathing and fluidity.
Study: NCT05676827

Intervention type: DIAGNOSTIC_TEST
Intervention: Diagnostic Criteria for Temporomandibular Disorders Clinical Examination
Description: Clinical examination made by experienced dentists (minimum 5 years of practice) and trained and calibrated in accordance with the protocol available on the DC/TMD.

Intervention type: DIAGNOSTIC_TEST
Intervention: Diagnostic Criteria for Temporomandibular Disorders Clinical Examination
Description: Clinical examination made by experienced dentists (minimum 5 years of practice) and trained and calibrated in accordance with the protocol available on the DC/TMD.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood test
Description: Blood samples will be tested to investigate two polymorphisms of genes encoding proteins for serotonin receptors HTR2A - rs4941573 in intron 3 and dopamine DRD3 - rs6280 (Ser9Gly) and levels of serotonin, dopamine, C-reactive protein, cortisol, sodium, potassium, and calcium.

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood test
Description: Blood samples will be tested to investigate two polymorphisms of genes encoding proteins for serotonin receptors HTR2A - rs4941573 in intron 3 and dopamine DRD3 - rs6280 (Ser9Gly) and levels of serotonin, dopamine, C-reactive protein, cortisol, sodium, potassium, and calcium.
Study: NCT05113498

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: (-)-Epicatechin
Description: Administration of a capsule with 150 mg of pure (-)-epicatechin after 48h low-flavanol diet.
Study: NCT05871372

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Brain Stimulation
Description: Both patients in the depression and epilepsy cohort will have implanted intracranial stereo-EEG (sEEG) electrodes as part of their clinical trial and regular clinical care, respectively, The depression cohort will also have deep brain stimulation (DBS) leads implanted as part of their trial. We will deliver stimulation via the DBS and sEEG electrodes. We will adhere to well known safety parameters.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: sEEG Stimulation
Description: Both patients in the depression and epilepsy cohort will have implanted intracranial stereo-EEG (sEEG) electrodes as part of their clinical trial and regular clinical care. We will deliver stimulation via the sEEG electrodes. We will adhere to well known safety parameters.
Study: NCT04757922

Intervention type: PROCEDURE
Intervention: Opportunistic salpingectomy / bilateral salpingectomy
Description: An opportunistic salpingectomy refers to removal of the salpinges without the ovaries during (laparoscopic) interventions for benign (gynaecological) disease to reduce the number of ovarian cancer cases. Therefore, a so-called opportunistic salpingectomy is a method of female sterilization.
Study: NCT05425095

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Buteyko Breathing Technique
Description: Group A will be treated with Buteyko Breathing Technique. Patient in a relaxed sitting position will ask to take a gentle breath in (2 sec), breath out (3sec) followed by pinching the nose with hands to hold the breath. The therapist will count the no. of seconds the patient can comfortably hold the breath until feels the need to breathe in again. Followed by releasing the nose and continue breathing.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Corpse-Pose Technique
Description: Group B will be treated with Corpse-Pose Technique for 15-20 min.
Study: NCT05648838

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pivot Balloon Catheter
Description: mornitoring acute RV failure and reduction of Functional Tricuspid Regurgitation
Study: NCT05428553

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic resection: CSP/p-CSP
Description: Patients in the experimental arm will be assigned to receive CSP/p-CSP.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endoscopic resection: EMR/EPMR
Description: Patients in the historical control arm have already finished EMR/EPMR
Study: NCT06244537

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MR-linac
Description: Patients enrolled will be treated with MR-Linac with short course radiotherapy (25Gy/5F), followed by 4 cycles of mFOLFOX6 or 3 cycles of XELOX chemotherapy, then radical surgical resection, and then postoperatively with 8 cycles of mFOLFOX6 or 5 cycles of XELOX chemotherapy.
Study: NCT05846867

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: AK112 IV every 2 weeks.intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: AK112 IV every 2 weeks.intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK112
Description: AK112 IV every 2 weeks.intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Oxaliplatin: 85mg/m2, intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Irinotecan 180mg/m2, intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium folinate
Description: Calcium folinate: 400mg/m2, intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium folinate
Description: Calcium folinate: 400mg/m2, intravenous infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Fluorouracil 400mg/m2, intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Fluorouracil 400mg/m2, intravenous injection
Study: NCT06110949

Intervention type: DEVICE
Intervention: Triaxial accelerometry
Description: A group of patients will be controlled with triaxial accelerometer (GENEActiv watch) on left wrist at a sampling rate of 85,70 Hz to measure movement in the x, y, and z direction, in order to collect raw data regarding patient mobility (duration of sleep, the time spent in sedentary attitudes and the amount of light, moderate and vigorous physical activity) during the admission (from the admission day to discharge).

Intervention type: DEVICE
Intervention: Triaxial accelerometry
Description: A group of patients will be controlled with triaxial accelerometer (GENEActiv watch) on left wrist at a sampling rate of 85,70 Hz to measure movement in the x, y, and z direction, in order to collect raw data regarding patient mobility (duration of sleep, the time spent in sedentary attitudes and the amount of light, moderate and vigorous physical activity) during the admission (from the admission day to discharge).
Study: NCT05334550

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home Based Early Intervention by Parent
Description: Through a video communication program called ZOOM, the parents of intervention group are educated once every two weeks for three months. Parent education consists of a program developed by our pediatric rehabilitation therapist to help premature infants develop motor skills. Parents provide daily exercise training to their children as educated.
Study: NCT05789849

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Collecting blood pressure measurements with noninvasive blood pressure device
Description: Noninvasive blood pressure measurements will collected based on the recommendations of the International Organization for Standardization (ISO) 81060-2:2018+A1:2020 Non-invasive sphygmomanometers -Clinical investigation of intermittent automated measurement type. This study has only 1 arm; investigational NIBP measurements will be collected using a NIBP Auscultatory Algorithm with alternating NIBP measurements collected using a reference sphygmomanometer.
Study: NCT06275191

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multicomponent intervention
Description: The multicomponent intervention consists of (1) a single 45-60-minute academic detailing session with provider participants, plus (2) provision of patient post-extraction instruction materials and (3) provision of blister-packaged acetaminophen and ibuprofen for distribution to adolescent/young adult patients after tooth extraction in the course of clinical practice

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: No intervention.
Study: NCT05351554

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Namilumab
Description: Namilumab administered subcutaneously

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered subcutaneously to match namilumab dosing

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Open label Namilumab
Description: Namilumab administered subcutaneously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone or equivalent

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Prednisone
Description: Prednisone or equivalent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone or equivalent
Study: NCT05631353

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Carriere Motion Appliance
Description: Patient will be randomly allocated into two groups:~Group I: conventional mandibular anchorage using passive lingual arch. Group II: anchorage by direct mini-screws. In the group I, Class II elastics will be attached from the maxillary canine to the mandibular first molar bilaterally with passive lingual arch in the lower arch as anchorage means.~In the group I, Class II elastics will be attached from the maxillary canine to mandiular miniscrews bilaterally.~For each patient, two CBCT radiographs will be obtained: one preoperatively and another after completion of distalization.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Carriere Motion Appliance
Description: Patient will be randomly allocated into two groups:~Group I: conventional mandibular anchorage using passive lingual arch. Group II: anchorage by direct mini-screws. In the group I, Class II elastics will be attached from the maxillary canine to the mandibular first molar bilaterally with passive lingual arch in the lower arch as anchorage means.~In the group I, Class II elastics will be attached from the maxillary canine to mandiular miniscrews bilaterally.~For each patient, two CBCT radiographs will be obtained: one preoperatively and another after completion of distalization.
Study: NCT04969510

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10 mg PRAX-114
Description: Once daily oral treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 20 mg PRAX-114
Description: Once daily oral treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 40 mg PRAX-114
Description: Once daily oral treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 60 mg PRAX-114
Description: Once daily oral treatment

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Once daily oral treatment
Study: NCT03972449

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BEAT-Speech
Description: BEAT-Speech integrates beatboxing techniques within speech-therapy services for individuals with speech sound disorders.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Traditional Articulation Approach
Description: The traditional approach to treating speech sound disorders focus on one or two sounds at a time until they are mastered by the client. Perceptual and production training are used with target starting at simple (isolation) and moving to more complex (sentences). A variety of cues such as shaping and phonetic placement cues are used.
Study: NCT05154435

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: mostcare hemodynamic monitor
Description: mostcare hemodynamic monitoring integrated into the radial artery catheter. According to the data obtained, intraoperative fluid management was arranged with certain algorithms.
Study: NCT05752071

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Gastric electric pacemaker
Description: Mounting of a temporary gastric pacemaker

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gastric electric pacemaker
Description: Mounting of a temporary gastric pacemaker
Study: NCT06477484

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood biomarker
Description: Blood biomarker
Study: NCT06178588

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tumor biopsy
Study: NCT04821531

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PT Pal
Description: Patients will be guided through individualized exercises that will be selected by their primary physical therapists. The exercises aim to improve lung function, maintain joint flexibility, muscle strength balance and mobility

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Manual
Description: Patients will be guided through individualized exercises that will be selected by their primary physical therapists. The exercises aim to improve lung function, maintain joint flexibility, muscle strength, balance and mobility
Study: NCT04839653

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral Paste(0,5 g) containing 10 mg of polymyxin B, 10 mg of gentamycin and 150 mg of amphotericine B or 500 000 U of nistatin q6h
Description: The oral paste will be applied topically on the oropharyngeal mucosa q6h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Suspension (10 ml) containing 100 mg of polymyxin B, 80 mg of gentamycin, 350 mg of amphotericine B or 8000000 U of nistation and 500 mg of vancomycin q6h
Description: The suspension will be administered through the nasogastric tube q6h.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravenous Antibacterial Agent - a 3-day course of systemic cefotaxime 1 g q6h or ceftriaxone 1 g qd
Description: Patients who do not receive systemic antibiotics for other reasons will get a short course of systemic antibiotic
Study: NCT06554249

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Vulsellum group
Description: The patients are asked to empty the bladder before IUD insertion. The vulsellum is applied on the cervix, sounding of the uterus is done and the IUD is inserted according to the standard technique of IUD insertion.~Pain intensity is assessed after the procedure using a visual analogue scale.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound group
Description: During the two hour period before IUD insertion, the patients are asked to drink about one liter of water and to avoid micturition.~Abdominal ultrasound is used to obtain a sagittal view of the uterus and the IUD is introduced into the uterine cavity under ultrasound guidance.~The vulsellum and uterine sound are not used during IUD insertion. Pain intensity is assessed after the procedure using a visual analogue scale..