TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05628415

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-powered AeonTM Endostapler (according to manufacturer medical device classification IIb)
Description: Closure of the left and/or right side of the lung after bilateral or unilateral lung-volume-reduction- surgery is performed with the non-powered Aeon™ Endostapler (Lexington medical) 60-mm and 45-mm. At the end of the operation, two 24F apical chest tubes are placed on each side and are systematically set at -10 cm H2O suction via the Medela- Topaz™ system. Air leak will be measured quantitatively in ml per minute by use of a Medela-Topaz™ system. Cessation of air leak is the case when a value of 0ml/min or two consecutive values under 30 ml/min by use of thoracic drainage Medela- Topaz™ system are read.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Echelon FLEX™ Powered plus Stapler (according to manufacturer medical device classification IIb)
Description: Closure of the left and/or right side of the lung after bilateral or unilateral lung-volume-reduction- surgery is performed with the Echelon FLEX™ Powered plus Stapler (Ethicon) 60-mm and 45-mm. At the end of the operation, two 24F apical chest tubes are placed on each side and are systematically set at -10 cm H2O suction via the Medela- Topaz™ system. Air leak will be measured quantitatively in ml per minute by use of a Medela-Topaz™ system. Cessation of air leak is the case when a value of 0ml/min or two consecutive values under 30 ml/min by use of thoracic drainage Medela- Topaz™ system are read.
Study: NCT06433544

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 6-week online mindfulness course
Description: The experimental group received a 6-week online mindfulness course, once a week for 90 minutes each session.
Study: NCT06092580

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AWT020
Description: Participants receiving AWT020 once every two weeks at designated dose levels
Study: NCT06469359

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Transcriptomics
Description: Transcriptomics to quantify the gene expression of immunological markers in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Transcriptomics
Description: Transcriptomics to quantify the gene expression of immunological markers in blood

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Transcriptomics
Description: Transcriptomics to quantify the gene expression of immunological markers in blood
Study: NCT06275490

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Partially Demineralized Dentin Block
Description: The extracted tooth will undergo grinding using the tooth transformer device. The produced dentin graft will be of a particle size 400-800 μm. Afterwards.~-Prepare the partially demineralized dentin block, the L-PRF membranes will be cut into small pieces and mixed with the dentin particles at a ratio of 2 membranes to 0.5 g of dentin, providing a 1:1 volume ratio. The liquid fibrinogen will be added to the homogeneous mixture, and while shaping the mixture into the desired form it will be gently stirred for approximately 10 seconds. Within a few minutes, the fibrinogen will convert into fibrin primarily from the activated blood platelets in the chopped L-PRF membranes. This process will effectively trap the biomaterial and the L-PRF pieces, forming a sturdy block known as the dentin block, which serves as a convenient and compact graft .The extracted socket will be filled with partially demineralized autogenous dentin graft.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Partially Demineralized Dentin Block
Description: The extracted tooth will undergo grinding using the tooth transformer device. The produced dentin graft will be of a particle size 400-800 μm. Afterwards.~-Prepare the partially demineralized dentin block, the L-PRF membranes will be cut into small pieces and mixed with the dentin particles at a ratio of 2 membranes to 0.5 g of dentin, providing a 1:1 volume ratio. The liquid fibrinogen will be added to the homogeneous mixture, and while shaping the mixture into the desired form it will be gently stirred for approximately 10 seconds. Within a few minutes, the fibrinogen will convert into fibrin primarily from the activated blood platelets in the chopped L-PRF membranes. This process will effectively trap the biomaterial and the L-PRF pieces, forming a sturdy block known as the dentin block, which serves as a convenient and compact graft .The extracted socket will be filled with partially demineralized autogenous dentin graft.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: L-PRF block
Description: The same procedure will be performed for preparing the L-PRF block by mixing the L-PRF membranes with xenograft. In both groups, the placed graft will be covered with a L-PRF membrane .The L-PRF clots obtained after 12 min of centrifugation will be placed in the Xpression box (IntraSpin, Intra-Lock, Florida, USA) for 5 min to gently compress (by gravity) into membranes.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: L-PRF block
Description: The same procedure will be performed for preparing the L-PRF block by mixing the L-PRF membranes with xenograft. In both groups, the placed graft will be covered with a L-PRF membrane .The L-PRF clots obtained after 12 min of centrifugation will be placed in the Xpression box (IntraSpin, Intra-Lock, Florida, USA) for 5 min to gently compress (by gravity) into membranes.
Study: NCT04841200

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chinese medicine compound combined with symptomatic treatments
Description: All patients were given symptomatic treatment according to consensus of Chinese experts on pneumoconiosis treatment (2018).~There are 3 Recipe for the 3 traditional Chinese syndrome.~Yang Qing Chen Fei Granules for syndrome of yin deficiency and heat-dryness, Bao Jin Chen Fei Granules for syndrome of pulmonary qi deficiency, Jin Shui Chen Fei Granules syndrome of deficiency of pulmonary and renal qi~All drugs were made into granules by Sichuan Neo-Green Pharmaceutical Technology Development Co., Ltd.~Each type of granule will be given orally, twice a day, for 52 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Chinese medicine compound placebo combined with symptomatic treatments
Description: All patients were given symptomatic treatment according to consensus of Chinese experts on pneumoconiosis treatment (2018).~There are 3 placebo Recipe for the 3 traditional Chinese syndrome.~Yang Qing Chen Fei Granules placebo for syndrome of yin deficiency and heat-dryness, Bao Jin Chen Fei Granules placebo for syndrome of pulmonary qi deficiency, Jin Shui Chen Fei Granules placebo for syndrome of deficiency of pulmonary and renal qi~All drugs were made into granules by Sichuan Neo-Green Pharmaceutical Technology Development Co., Ltd. The appearance, shape, color and packaging of Chinese medicine compound placebo are the same as those of drugs.~Each type of granule will be given orally, twice a day, for 52 weeks.
Study: NCT06578728

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: 25mg/mL intralesional injection into nail bed/nail matrix

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triamcinolone Acetonide 10mg/mL
Description: 10mg/mL intralesional injection into nail bed/nail matrix

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: saline intralesional injection into nail bed/nail matrix
Study: NCT04784780

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elobixibat 10mg
Description: Patients with chronic constipation are administered Elobixibat 10mg for 12 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients with chronic constipation are administered placebo for 12 weeks
Study: NCT06110182

Intervention type: DIETARY_SUPPLEMENT
Intervention: enteral or parenteral nutritional support
Description: Parents will be classified based on whether they received enteral or parenteral nutritional support during treatment.
Study: NCT05129020

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sparrow Fledging Therapy System
Description: tAN sessions will be administered up to four times per day for up to 20 days total. Active tAN will be set to run for 30 minutes one hour prior to each planned morphine dose. When the 30-minute tAN session is complete, the system will be turned off and unplugged.
Study: NCT05980767

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Temporary Peripheral Nerve Stimulation System
Description: Single use medical device. Therapy consists of single, 1 hour dose of electrical stimulation.
Study: NCT05129020

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Sparrow Fledging Therapy System
Description: Participants randomized to the sham group will have the device earpiece applied at the same timepoints and for the same duration as the active group, but stimulation will not be turned on. tAN sessions will be administered up to four times per day for up to 20 days total. Sham tAN will be set to run for 30 minutes one hour prior to each planned morphine dose. When the 30-minute tAN session is complete, the system will be turned off and unplugged.
Study: NCT06649201

Intervention type: OTHER
Intervention: Vulvovaginal Symptom Questionnaire
Description: Participants will undergo assessment of vulvovaginal symptoms via the vulvovaginal questionnaire once pre-transplant, six months, and develop months post-transplant.

Intervention type: DIAGNOSTIC_TEST
Intervention: Vaginal Microbiome Evaluation
Description: A vaginal microbiome evaluation will be performed via vaginal exam by a gynecologist with collection of vaginal samples once pre-transplant, six months, and twelve months post-transplant.
Study: NCT06386146

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JAB-30355
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JAB-30355
Description: Oral administration
Study: NCT04446585

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automated External Defibrillator (AED)
Description: Deployment of AEDs

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training in cardiopulmonary resuscitation and AED use
Description: Residents will undergo 30-minute courses at study start and if needed during the trial period. During the course they will also be recruited as citizen responders

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activation of citizen responders
Description: Citizen responders will be activated in case of suspected cardiac arrest through the heart runner app.
Study: NCT05466110

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal Cord Stimulation
Description: Epidural application of electrical current to the spinal cord

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Spinal Fusion Surgery
Description: screw-rod system based spinal instrumentation
Study: NCT06092398

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PRP and PRFG in treatment of anal fistula
Description: The tract fistula was cleaned with betadine 10% before PRP and PRFP were applied. Then, 2 ml of PRP was injected around the fistula into the tissue (the penetration depth in injection was 5-6 mm), and 4 ml PRFP was mixed with 1 m thrombin and interpositioned into the tract. 2 ml of PRP was injected around the fistula into the tissue (the penetration depth in injection was 5-6 mm), and 4 ml PRFP was mixed with 1 m thrombin and interpositioned into the tract. The operation time was about 20-30 minutes, the clot formation usually takes about 8 minutes, but the anesthesia was extended to 20 minutes to make sure a complete clot in the place of fistula
Study: NCT05004467

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobilization With Movement Technique
Description: The researcher explains cervical movements to the patient to be done while the technique is performed. This movements will be the painful and limited movements detected in goniometric intervention before the treatment and movements done actively and in all range of motion.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mobilization With Movement Technique
Description: The researcher explains cervical movements to the patient to be done while the technique is performed. This movements will be the painful and limited movements detected in goniometric intervention before the treatment and movements done actively and in all range of motion.
Study: NCT05325112

Intervention type: DIAGNOSTIC_TEST
Intervention: FFRCT
Description: FFRCT is a diagnostic test following a CCTA to help diagnose and treat coronary artery disease.
Study: NCT05452902

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EXCAP Exercise
Description: 12 weeks of at-home walking and resistance exercise.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Nutrition Education
Description: 12 weeks of implementing eating tips and tracking food.
Study: NCT05189106

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baricitinib
Description: Each participant will be treated with open-label baricitinib for 24 weeks. Participants will receive 2 mg baricitinib by mouth daily for the first 8 weeks and 4 mg baricitinib by mouth daily for the remaining 16 weeks.
Study: NCT05724784

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Flourish
Description: Flourish is a text messaging program that aims to improve coping following cyberbullying and reduce suicide risk among youth.
Study: NCT05822375

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Better Together Physician Coaching
Description: Better Together Physician Coaching Program thought-based coaching. This type of coaching focuses on thoughts and beliefs. It combines a cognitive behavioral therapy (CBT) model with mindfulness-based awareness and integrates theories of acceptance and commitment therapy (ACT), nonattachment, and radical questioning from Socratic and Greek philosophies. BT delivers a robust coaching experience via a 4-month web-based, group-coaching model. This novel program allows residents to participate as actively as they are inclined and able, offering flexibility via multiple modalities of coaching: twice weekly group coaching calls, unlimited anonymous written coaching, and weekly self-study modules that are housed on a secure members-only website.
Study: NCT06116617

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SRSD107
Description: SRSD107 is a synthetic, chemically modified double-stranded, small interfering ribonucleic acid (siRNA).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sodium chloride
Study: NCT04732325

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Researchers will program the spinal cord stimulation (SCS) system to deliver, according to the randomization status of the participant, burst, kHz, tonic, and sham stimulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Researchers will program the spinal cord stimulation (SCS) system to deliver, according to the randomization status of the participant, burst, kHz, tonic, and sham stimulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Researchers will program the spinal cord stimulation (SCS) system to deliver, according to the randomization status of the participant, burst, kHz, tonic, and sham stimulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Researchers will program the spinal cord stimulation (SCS) system to deliver, according to the randomization status of the participant, burst, kHz, tonic, and sham stimulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Researchers will program the spinal cord stimulation (SCS) system to deliver, according to the randomization status of the participant, burst, kHz, tonic, and sham stimulation.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal cord stimulation
Description: Researchers will program the spinal cord stimulation (SCS) system to deliver, according to the randomization status of the participant, burst, kHz, tonic, and sham stimulation.
Study: NCT06532344

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-7913
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-4538
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levofolinate
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Specified dose on specified days
Study: NCT04862039

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality (VR) devices
Description: Virtual Reality (VR) devices. Subjects receiving the experimental treatment will be given a VR headset, headphones and wristband and the Philips wireless fetal-maternal monitoring system, after the necessary preparation of the abdominal skin.
Study: NCT05543135

Intervention type: DIAGNOSTIC_TEST
Intervention: basic audiological evaluation
Description: pure tone audiometry\&immitancemetry
Study: NCT04797663

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nd-YAG laser
Description: laser hair removal device
Study: NCT05535010

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transforaminal epidural steroid injection(TFESI)
Description: TFESI procedure will be applied again in the 3rd week and 3rd month for the patients whose NRS score decreased by less than 50 percent after the first procedure.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transforaminal epidural steroid injection(TFESI)
Description: TFESI procedure will be applied again in the 3rd week and 3rd month for the patients whose NRS score decreased by less than 50 percent after the first procedure.
Study: NCT04797663

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCA 20%
Description: chemical peel
Study: NCT05847972

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: MWM (Mobilization with movement)
Description: This manipulation is intended to improve ankle dorsiflexion. One session of 3 sets of 20 slow ankle dorsiflexion's separated by 10 seconds of rest will be performed.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MWM (Mobilization with movement)
Description: This manipulation is intended to improve ankle dorsiflexion. One session of 3 sets of 20 slow ankle dorsiflexion's separated by 10 seconds of rest will be performed.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Plantar orthoses
Description: Procedure: MWM All participants will undergo MWM. This manipulation is intended to improve ankle dorsiflexion. One session of 3 sets of 20 slow ankle dorsiflexion's separated by 10 seconds of rest will be performed.~Procedure: Plantar orthoses The moulds will be taken immediately after the manipulation. The PO will be made of resin (0.8mm +1.2mm), 2mm hard EVA heel stabiliser, 3mm semi-hard EVA cover. The PO should be worn for 3 months to obtain the results of the study.
Study: NCT04629326

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 68Ga-WL12 PET/CT
Description: WL12, labeled with PET radio-nuclide ( Ga-68 )will be used as a molecular imaging tracer for PET/CT scanning
Study: NCT05476588

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Screening
Description: Screening and validation of assessment tool translated into Spanish

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Screening
Description: Screening and validation of assessment tool translated into Spanish
Study: NCT05442034

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: growth factors to help in regeneration
Description: regenerative therapy

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: growth factors to help in regeneration
Description: regenerative therapy
Study: NCT05130957

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage Application with clove oil
Description: The experimental group is given a massage with clove oil,

Intervention type: OTHER
Group type: OTHER
Intervention: Massage Application without any oil
Description: The control group is given a massage without any oil as a standard midwifery care.
Study: NCT05818605

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate Intensity Exercise Program
Description: Subjects randomized to the EXER arm will undergo 24 weeks of Moderate Intensity Exercise Training (MIET). Patients will be signed up for 60-minute exercise sessions, 3 times a week
Study: NCT05254054

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: whole body vibration
Description: The whole body vibration is used when vibrations (mechanical oscillations) of a certain frequency are transferred to the human body. Humans are exposed to vibration through a contact surface that is in a mechanical vibrating state. It has been considered as an alternative and safe method for neuromuscular training and may be incorporated into current neuromuscular rehabilitation programs so as to enhance muscle recovery

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional exercise training
Description: A set of conventional exercises designed for ACL rehabilitation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional exercise training
Description: A set of conventional exercises designed for ACL rehabilitation
Study: NCT04809077

Intervention type: OTHER
Group type: OTHER
Intervention: Reverse total shoulder replacement
Description: Long-term radiographic and clinical data of patients who underwent a reverse shoulder replacement
Study: NCT05847972

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Plantar orthoses
Description: Procedure: MWM All participants will undergo MWM. This manipulation is intended to improve ankle dorsiflexion. One session of 3 sets of 20 slow ankle dorsiflexion's separated by 10 seconds of rest will be performed.~Procedure: Plantar orthoses The moulds will be taken immediately after the manipulation. The PO will be made of resin (0.8mm +1.2mm), 2mm hard EVA heel stabiliser, 3mm semi-hard EVA cover. The PO should be worn for 3 months to obtain the results of the study.
Study: NCT05153408

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-701
Description: BLU-701 for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-701
Description: BLU-701 for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-701
Description: BLU-701 for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-701
Description: BLU-701 for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: osimertinib
Description: Osimertinib tablets for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: carboplatin
Description: IV infusion of carboplatin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pemetrexed
Description: IV infusion of pemetrexed