TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04806737

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Teriflunomide Oral Tablet
Description: The study will be conducted with two treatment groups in the form of a 2:1 parallel group comparison and will serve to compare oral treatment with 14 mg/d teriflunomide vs. placebo in subjects with well-controlled coeliac disease undergoing gluten challenge. The screening period will be up to 8 weeks, followed by a 7-day run-in treatment period with a loading dose of teriflunomide followed by a 6 day therapeutic maintenance dose, an initial 4-week treatment-free follow-up period and a 6 month closing follow-up.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Teriflunomide Oral Tablet
Description: The study will be conducted with two treatment groups in the form of a 2:1 parallel group comparison and will serve to compare oral treatment with 14 mg/d teriflunomide vs. placebo in subjects with well-controlled coeliac disease undergoing gluten challenge. The screening period will be up to 8 weeks, followed by a 7-day run-in treatment period with a loading dose of teriflunomide followed by a 6 day therapeutic maintenance dose, an initial 4-week treatment-free follow-up period and a 6 month closing follow-up.
Study: NCT05581199

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo SC
Study: NCT05355389

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive training
Description: For the cognitive treatment intervention the widely used cognitive training program RehaCom will be used. This is a computer-aided program with more than 30 modules focusing on different domains of cognition. RehaCom has shown improvements in verbal learning, visuospatial memory, information processing speed, attention, executive functions, depression, fatigue and quality of life in PwMS (PMID 31927200, 28116167, 19825502, 23192417). Patients will train on their home computer without direct therapist supervision, using three RehaCom modules that are focused on improving working memory. Both patients in the combined intervention and the cognitive intervention group will be doing a 45-minute computer session respectively one and two days per week for a total of 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive training
Description: For the cognitive treatment intervention the widely used cognitive training program RehaCom will be used. This is a computer-aided program with more than 30 modules focusing on different domains of cognition. RehaCom has shown improvements in verbal learning, visuospatial memory, information processing speed, attention, executive functions, depression, fatigue and quality of life in PwMS (PMID 31927200, 28116167, 19825502, 23192417). Patients will train on their home computer without direct therapist supervision, using three RehaCom modules that are focused on improving working memory. Both patients in the combined intervention and the cognitive intervention group will be doing a 45-minute computer session respectively one and two days per week for a total of 12 weeks.
Study: NCT04786678

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cell phone notification
Description: Habitual bed and wake times will be detected using a wearable for 4 weeks. Using habitual wake time, a minimum bedtime to achieve adequate sleep will be calculated (8 hours). If phone usage is detected after this minimum bedtime, participants will receive a notification informing them they are awake past their minimum bedtime and recommend they go to bed to obtain adequate sleep.
Study: NCT04535492

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Decision Making Support Tool
Description: Primary care practices randomized in a stepped wedge cluster design will implement a newly developed predictive model and analytic tool to improve shared decision-making for patients.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Decision Making Support Tool
Description: Primary care practices randomized in a stepped wedge cluster design will implement a newly developed predictive model and analytic tool to improve shared decision-making for patients.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Decision Making Support Tool
Description: Primary care practices randomized in a stepped wedge cluster design will implement a newly developed predictive model and analytic tool to improve shared decision-making for patients.
Study: NCT04707066

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treatment As Usual (TAU)
Description: Treatment As Usual

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treatment As Usual (TAU)
Description: Treatment As Usual

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treatment As Usual (TAU)
Description: Treatment As Usual

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 1
Description: Collaborative Assessment and Management of Suicidality

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 1
Description: Collaborative Assessment and Management of Suicidality

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 1
Description: Collaborative Assessment and Management of Suicidality
Study: NCT05355389

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motor training
Description: For the motor treatment intervention a patient-tailored aerobic training program will be used. Based on their baseline physical activity level patients can choose out of a number of aerobic activities of either mild, moderate or strenuous intensity, with a total training time of 90 minutes for the motor intervention group and 45 minutes for the combined intervention group, divided over at least two training sessions per week of at least 15 minutes per session. The training will be carried out individually at home, without therapist supervision. All physical activities will be logged using the sport watch equipped with a heart rate sensor and an accelerometer. Training intensity will be assessed using the patient's heart rate and the Rating of Perceived Exertion scale.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Motor training
Description: For the motor treatment intervention a patient-tailored aerobic training program will be used. Based on their baseline physical activity level patients can choose out of a number of aerobic activities of either mild, moderate or strenuous intensity, with a total training time of 90 minutes for the motor intervention group and 45 minutes for the combined intervention group, divided over at least two training sessions per week of at least 15 minutes per session. The training will be carried out individually at home, without therapist supervision. All physical activities will be logged using the sport watch equipped with a heart rate sensor and an accelerometer. Training intensity will be assessed using the patient's heart rate and the Rating of Perceived Exertion scale.
Study: NCT05036148

Intervention type: OTHER
Intervention: Data analysis
Description: MH registry data will be screened for MH positive diagnosis
Study: NCT06107218

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bioactive Glass Air Abrasion Particles.
Description: Finishing of cavity walls by AquaCare Air Abrasion Device using Bioactive Glass Air Abrasion Particles.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diamond Stone.
Description: Finishing of cavity walls using Diamond Stone.
Study: NCT05171569

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual care with remote automated monitoring (RAM)
Description: Use of Cloud Diagnostics connected health kit for at home monitoring with virtual clinical from nursing and perioperative physician team.
Study: NCT04707066

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialectical Behavior Therapy (DBT) - Phase 2
Description: Dialectical Behavior Therapy

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialectical Behavior Therapy (DBT) - Phase 2
Description: Dialectical Behavior Therapy

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Maintenance/Monitoring - Phase 2
Description: Maintenance/Monitoring

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Maintenance/Monitoring - Phase 2
Description: Maintenance/Monitoring

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 2
Description: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 2

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 2
Description: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 2
Study: NCT06399263

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: The psilocybin will include two dose administration sessions, first a 20mg administration, and second a 30mg administration.
Study: NCT04696159

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pyloromyotomy
Description: Endoscopic Per-Oral Pyloromyotomy (POP)
Study: NCT04494412

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanamivir
Description: Zanamivir solution for infusion will be available as a 10 milligrams per milliliters (mg/mL) vial. DECTOVA is approved for age groups 6 months and above.
Study: NCT04640051

Intervention type: PROCEDURE
Intervention: LAAO
Description: LAAO by use of 3D in silico simulation by FEops HEARTguide as part of the pre-procedural assessment and device size selection
Study: NCT05590091

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Parenteral nutrition;Enteral nutrition
Description: The intelligent nutrition management system was used to carry out standardized nutrition management of patients after hematopoietic stem cell transplantation
Study: NCT06399263

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Preparation and Integration Sessions
Description: The psilocybin therapy will include three preparatory sessions, two dose A integration sessions, and four final integration sessions.
Study: NCT06372379

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT06424704

Intervention type: DIAGNOSTIC_TEST
Intervention: Microbiological culture
Description: Samples taken from chronic suppurative otitis media patients in the Medical Microbiology Laboratory of Selçuk University Faculty of Medicine will be planted in 5% sheep blood Columbia agar, eosin methylene blue agar and saboraud dextrose agar, and the media will be incubated at 37oC for 24-48 hours. Growing bacteria and fungi were examined using traditional methods \[Gram staining, catalase test, coagulase test, bacitracin disk, PYR test (L-pyrrolidonyl-β-naphthylamide), oxidase test, IMViC test, lactophenol cotton blue, etc.\] and VITEK 2 (bioMerieux, France).

Intervention type: DIAGNOSTIC_TEST
Intervention: Microbiological culture
Description: Samples taken from chronic suppurative otitis media patients in the Medical Microbiology Laboratory of Selçuk University Faculty of Medicine will be planted in 5% sheep blood Columbia agar, eosin methylene blue agar and saboraud dextrose agar, and the media will be incubated at 37oC for 24-48 hours. Growing bacteria and fungi were examined using traditional methods \[Gram staining, catalase test, coagulase test, bacitracin disk, PYR test (L-pyrrolidonyl-β-naphthylamide), oxidase test, IMViC test, lactophenol cotton blue, etc.\] and VITEK 2 (bioMerieux, France).
Study: NCT06644755

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-2243a
Description: Escalation Part: DS-2243a will be administered at escalating doses to determine the RDE~Expansion Part: DS-2243a will be administered at RDE

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-2243a
Description: Escalation Part: DS-2243a will be administered at escalating doses to determine the RDE~Expansion Part: DS-2243a will be administered at RDE

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-2243a
Description: Escalation Part: DS-2243a will be administered at escalating doses to determine the RDE~Expansion Part: DS-2243a will be administered at RDE

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-2243a
Description: Escalation Part: DS-2243a will be administered at escalating doses to determine the RDE~Expansion Part: DS-2243a will be administered at RDE

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-2243a
Description: Escalation Part: DS-2243a will be administered at escalating doses to determine the RDE~Expansion Part: DS-2243a will be administered at RDE
Study: NCT05725577

Intervention type: OTHER
Group type: OTHER
Intervention: care via the telemedicine system
Description: Care via the telemedicine system

Intervention type: OTHER
Group type: OTHER
Intervention: Routine care
Description: Routine care
Study: NCT05469815

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lost Children Society Game
Description: 36 online therapeutic role-playing sessions spread over 36 weeks, one session per week
Study: NCT05166655

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Movement task
Description: Computer task with experimental conditions manipulating sensory and motivation cues for movement.
Study: NCT05654623

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARV-471
Description: orally, once daily on a 28-day continuous dosing schedule

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fulvestrant
Description: intramuscularly on Days 1 and 15 of Cycle 1 and then on Day 1 of each cycle starting from C2D1 (28-day cycle)
Study: NCT03821142

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transvaginal mesh for anterior pelvic organ prolapse repair
Description: synthetic mesh for anterior pelvic organ prolapse with or without apical vaginal wall involvement via the vaginal route in a highly selected patient population
Study: NCT05748639

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile health application
Description: Participants randomized to receive the QG-A (Experimental) intervention will receive monthly appointments with a medical provider, access to naltrexone, and weekly and bi-weekly appointments with a licensed clinical counselor through an integrated digital health application.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Medical Management
Description: Participants randomized to receive the MM (Control) intervention will receive monthly appointments with a medical provider and access to naltrexone.
Study: NCT04770714

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Breast MRI
Description: Standard of Care Breast MRI

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Contrast Enhanced Mammography
Description: Standard of Care Contrast Enhanced Mammography
Study: NCT06563050

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nebulized lidocaine
Description: Subjects in group A underwent nebulization with 5 mL of 2% lidocaine for 15 minutes by using a jet nebulizer.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lidocaine spray
Description: Subjects in group B will underwent 10% lidocaine spray solution will be sprayed 10 times at the oropharynx at 5 s interval.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combination of nebulized lidocaine and lidocaine spray
Description: Group C: both nebulization and spray will be performed in the same manner except the number of spray will be 2 instead 10.
Study: NCT06543186

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral health education lecture
Description: Conventional oral health education will be given by trained and calibrated dentists.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral health education via mHealth on WhatsaApp
Description: For the oral health education intervention via mHealth, WhatsApp medium will be used to disseminate oral health educational material

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral health education via Metaverse platform on Meta-OHE
Description: For oral health education intervention via Meta-OHE, it will be done via computer.
Study: NCT05058911

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-delivered exposure-based cognitive behavior therapy
Description: The primary treatment component is exposure to stimuli (situations and activities) that give rise to pain, distress, and unwanted emotional responses. The treatment proceeds in accordance with functional analysis. Exercises are tailored for the patient so that, for example, individuals whose main coping strategy is to be overly active (i.e., persistence behavior) are encouraged to sit down and observe pain and other aversive bodily sensations as they arise. The protocol also includes regular exercises where the participant is encouraged to observe and name physical sensations without acting on them.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Internet-delivered traditional cognitive behavior therapy
Description: This treatment is based on components typical of T-CBT for FM, such as relaxation, activity planning or pacing, cognitive restructuring techniques and stress management strategies.
Study: NCT06534307

Intervention type: BEHAVIORAL
Intervention: Questionnaire Child Behaviour Checklist
Description: The Child Behavior Checklist comprises items assigned to 8 subscales describing various behavioral areas. These subscales can be summed up to scores for internalizing and externalizing problems as well as a total score. Checklist scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean higher amount of problems.

Intervention type: BEHAVIORAL
Intervention: Questionnaire Child Behaviour Checklist
Description: The Child Behavior Checklist comprises items assigned to 8 subscales describing various behavioral areas. These subscales can be summed up to scores for internalizing and externalizing problems as well as a total score. Checklist scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean higher amount of problems.

Intervention type: BEHAVIORAL
Intervention: Questionnaire Young Self Report
Description: The Questionnaire Young Self Report comprises items assigned to 8 subscales describing various behavioral areas. These subscales can be summed up to scores for internalizing and externalizing problems as well as a total score.

Intervention type: BEHAVIORAL
Intervention: Questionnaire Young Self Report
Description: The Questionnaire Young Self Report comprises items assigned to 8 subscales describing various behavioral areas. These subscales can be summed up to scores for internalizing and externalizing problems as well as a total score.

Intervention type: DIAGNOSTIC_TEST
Intervention: physical examination
Description: physical development examination including height (in cm), weight (in g) and tanner states
Study: NCT06296459

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 3D R100 scanner
Description: A cone beam computed tomography used for planning of implant surgery

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Conventional Radiograph
Description: Imaging used as standard of care to plan for implant surgery
Study: NCT06440486

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Probiotics
Description: Serum and fecal samples were collected at the beginning and end of the study to evaluate the effects of probiotic consumption on immune markers, metabolites, and gut microbiota before and after administration.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics
Description: Serum and fecal samples were collected at the beginning and end of the study to evaluate the effects of probiotic consumption on immune markers, metabolites, and gut microbiota before and after administration.
Study: NCT06534307

Intervention type: DIAGNOSTIC_TEST
Intervention: physical examination
Description: physical development examination including height (in cm), weight (in g) and tanner states
Study: NCT05224739

Intervention type: PROCEDURE
Intervention: Minimally Invasive Liver Resection
Description: laparoscopic and robotic liver resections
Study: NCT06217835

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: To evaluate the response of an orthopedic insole
Description: To evaluate the response of an orthopedic insole of different heights on gait.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: To evaluate the response of an orthopedic insole
Description: To evaluate the response of an orthopedic insole of different heights on gait.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: To evaluate the response of an orthopedic insole
Description: To evaluate the response of an orthopedic insole of different heights on gait.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: evaluate activation of musculature
Description: To evaluate the response caused by an orthopedic insole of different heights on the indicated musculature.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: evaluate activation of musculature
Description: To evaluate the response caused by an orthopedic insole of different heights on the indicated musculature.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: evaluate activation of musculature
Description: To evaluate the response caused by an orthopedic insole of different heights on the indicated musculature.
Study: NCT05494580

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pamiparib
Description: Oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Surufatinib
Description: Oral
Study: NCT06433986

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Modified Coronally Advanced Tunnel (MCAT)Technique
Description: Scaling and root planing will be performed and after resolution of gingival inflammation, root coverage procedure will be done with Volume Stable Collagen Matrix(VCMX) using MCAT.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Vestibular Incision Subperiosteal Tunnel Access (VISTA)Technique
Description: Scaling and root planing will be performed and after resolution of periodontal inflammation, root coverage procedure will be done with Volume Stable Collagen Matrix(VCMX) using VISTA.