TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04795375

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity counseling
Description: The Physical activity counseling techniques will be based on the Self Determination Theory and Five A's (Assess, Advise, Agree, Assist, Arrange). Guidelines for physical activity will include combined aerobic and resistance exercises.~Each participant in the intervention group will receive personal exercise prescriptions in accordance the post-surgical statues and exercise recommendations after bariatric surgery. Participants will receive long term follow-up and accompaniment during the first six months after the surgery, through Personal meetings with a certified nurse, Phone-calls, motivational massages, and Exercise Videos.
Study: NCT06470516

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: high-frequency transcranial alternating current stimulation
Description: The experimental group received real stimulation of high-frequency transcranial alternating current stimulation (Hi-tACS).The treatment duration is 30 days, with two sessions per day, each lasting 40 minutes.The experimental group received Hi-tACS with parameters set at 77.5Hz and 15mA.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham high-frequency transcranial alternating current stimulation
Description: The the control group received sham stimulation of high-frequency transcranial alternating current stimulation (Hi-tACS).The treatment duration is 30 days, with two sessions per day, each lasting 40 minutes.The experimental group received Hi-tACS with parameters set at 0mA
Study: NCT06189170

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo
Study: NCT06111638

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Single dose intravenous injection of BBM-H803
Description: Single dose intravenous infusion of BBM-H803, an adeno-associated viral (AAV) vector derived from recombinant DNA techniques to contain an expression cassette of the human factor VIII transgene in liver. The dose of BBM-H803 will be calculated according to participant's weight.
Study: NCT05680467

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy
Description: The protocol will last 30 minutes and will include the application of the following manual techniques:~* Lumbar soft tissue and joint cranial and lateral mobilization with the patient in the supine position~* Bilateral medial lumbar soft tissue mobilization~* Functional massage on the quadratus lumborum muscle with the patient in a lateral position on both sides~* Extension with coupled sidebending mobilization of the thoracic area with the patient in a lateral position on both sides~* Soft tissue lateral mobilization of the thoracic area with the patient in a lateral position on both sides

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy plus TECAR
Description: The participants of this group will be given the same manual protocol as the first group in combination with the application of high frequency current. Soft tissue mobilization manipulations will be applied in combination with a capacitive conventional electrode and with a special electrode bracelet that makes the therapist's own hand as an antistatic electrode. The frequencies of the high frequency current will be 300khz, 500khz, and 1MHz, while as a reference electrode a flexible self-adhesive ground will be used placed on the abdomen

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants in this group will only receive general instructions about managing their back pain and counseling about avoiding activities that may worsen their symptoms.
Study: NCT06090058

Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of neurofilament light chain
Description: Serum samples will be collected into a serum gel with clotting activator tube (Sarstedt). After delivery to the laboratory, the serum samples were centrifuged at 2500 × g for 6 min at 4 Celsius degree, then aliquoted into at least three vials (0.3 mL per vial) and stored at -70 Celsius degree until the analysis.

Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of neurofilament light chain
Description: Serum samples will be collected into a serum gel with clotting activator tube (Sarstedt). After delivery to the laboratory, the serum samples were centrifuged at 2500 × g for 6 min at 4 Celsius degree, then aliquoted into at least three vials (0.3 mL per vial) and stored at -70 Celsius degree until the analysis.

Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of neurofilament light chain
Description: Serum samples will be collected into a serum gel with clotting activator tube (Sarstedt). After delivery to the laboratory, the serum samples were centrifuged at 2500 × g for 6 min at 4 Celsius degree, then aliquoted into at least three vials (0.3 mL per vial) and stored at -70 Celsius degree until the analysis.
Study: NCT06257225

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Guided Bone regeneration
Description: After local anesthesia, a crestal incision will be performed followed by full-thickness mucoperiosteal flap elevation Flap advancement will be attained through periosteal scoring of the buccal; The resorbable collagen membrane (Bio Gide, Geistlich AG) will be trimmed to the defect size. Xenograft (Bio-Oss) together with scrapped autogenous bone will be mixed and placed at the surgical site. The membrane will positioned over the graft and tucked into the lingual flap. Patient allocation concealment will be broken and the patients will be randomly assigned into two groups Patients receiving horizontal bone augmentation with resorbable collagen membrane stabilized with no tacks. The first layer will be closed with horizontal mattress sutures placed 4 mm from the incision line, and single interrupted sutures are used to close the edges of the flap. Vertical incisions are closed using single interrupted sutures and mattress suture should remain in place for at least 2 to 3 weeks

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Guided Bone regeneration
Description: After local anesthesia, a crestal incision will be performed followed by full-thickness mucoperiosteal flap elevation Flap advancement will be attained through periosteal scoring of the buccal; The resorbable collagen membrane (Bio Gide, Geistlich AG) will be trimmed to the defect size. Xenograft (Bio-Oss) together with scrapped autogenous bone will be mixed and placed at the surgical site. The membrane will positioned over the graft and tucked into the lingual flap. Patient allocation concealment will be broken and the patients will be randomly assigned into two groups Patients receiving horizontal bone augmentation with resorbable collagen membrane stabilized with no tacks. The first layer will be closed with horizontal mattress sutures placed 4 mm from the incision line, and single interrupted sutures are used to close the edges of the flap. Vertical incisions are closed using single interrupted sutures and mattress suture should remain in place for at least 2 to 3 weeks
Study: NCT05911971

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental
Description: specific reeducation (not detailed to maintain blinding of participants)

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham comparator
Description: sham reeducation (not detailed to maintain blinding of participants)
Study: NCT06397378

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: short videos related to HPV vaccines
Description: We will develop 4 new videos and revise 2 existing videos and hope to increase college students\&#39; intention to receive HPV vaccines.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CDC HPV Fact Sheet
Description: This intervention is an educational information that CDC provided to explain why you should receive HPV vaccines. https://www.cdc.gov/std/hpv/stdfact-hpv.htm
Study: NCT05190679

Intervention type: OTHER
Intervention: None/Observational Studies
Description: This is an observational study and there is no intervention.

Intervention type: OTHER
Intervention: None/Observational Studies
Description: This is an observational study and there is no intervention.

Intervention type: OTHER
Intervention: None/Observational Studies
Description: This is an observational study and there is no intervention.
Study: NCT06476288

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low-intensity resistance exercise training
Description: The intervention protocol will consist of 60 minutes of low-intensity resistance exercise training 3x/week for 6 weeks.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Low-intensity resistance exercise training
Description: The intervention protocol will consist of 60 minutes of low-intensity resistance exercise training 3x/week for 6 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High-Dose Remote ischemic conditioning (RIC)
Description: Treatment dose of RIC- the RIC cuff will be inflated to 20 mmHg over the participant's systolic blood pressure. The treatment dose of RIC will be applied in 4 sets of cycles with inflating the cuff and leaving it pumped for 5 minutes then deflating the cuff for an off period of 5 minutes. Total treatment time will be 35 minutes.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Low-Dose Remote ischemic conditioning (RIC)
Description: This dose will be the control for the study. Low-dose RIC- the RIC cuff will be inflated to 10 mmHg below the participant's diastolic blood pressure. The low-dose RIC will be applied in 4 sets of cycles with inflating the cuff and leaving it pumped for 5 minutes then deflating the cuff for an off period of 5 minutes. Total treatment time will be 35 minutes.
Study: NCT05554302

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-Fluciclovine
Description: Patients will receive 5-mCi dose (+/- 20%) of 18F-Fluciclovine intravenously as a bolus injection. They will be required to fast for at least four hours prior to 18F-Fluciclovine injection. Patients will be positioned for PET/CT brain imaging and will be injected with 18F-Fluciclovine immediately prior to PET data acquisition. PET data will be collected in list mode up to 25 minutes post-injection. PET images will be reconstructed in two ways: as a standard static image of data acquired between 10 to 20 minutes post-injection, and as a dynamic series of four 5-minute frames between 5 to 25 minutes post-injection to allow for motion assessment and correction and time-dependent observations.
Study: NCT04333615

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Exercise
Description: Three conditions will be tested: self-selected exercise, walking with pain exercise, and control session.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Three conditions will be tested: self-selected exercise, walking with pain exercise, and control session.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Three conditions will be tested: self-selected exercise, walking with pain exercise, and control session.
Study: NCT04992468

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ovulation triggering with GnRH-a+rhCG
Description: recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®) Micronized progesterone 200mg (Utrogestan®) Ovulation trigger: Triptorelin 0.2 mg (Decapeptyl®) + Recombinant human chorionic gonadotropin (rhCG) 250μg (Ovitrelle®)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ovulation triggering with GnRH-a
Description: rFSH 225-300 IU (Gonal-F®/Puregon®/Ovaleap®/ Rekovelle®) Micronized progesterone 200mg (Utrogestan®) Ovulation trigger: Triptorelin 0.2 mg (Decapeptyl®)
Study: NCT06063681

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR-8541A
Description: orally administered ENPP1 inhibitor
Study: NCT06189170

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo
Study: NCT04694625

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structured Rehabilitation Program
Description: Early Function Phase (Protective phase) week 1 Progressive Function Phase (Recovery Phase) 2nd and 3rd week Advance Function Phase (Activity Phase) 4th week

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physical Therapy
Description: • Rapid post-operative mobilization • Range of motion exercises started • Passive extension by placing pillow under foot • Flexion-by dangling the leg over the side of bed • Muscle strengthening exercises • Weight bearing is allowed on 1st post-operative

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy
Description: • Rapid post-operative mobilization • Range of motion exercises started • Passive extension by placing pillow under foot • Flexion-by dangling the leg over the side of bed • Muscle strengthening exercises • Weight bearing is allowed on 1st post-operative
Study: NCT05070130

Intervention type: DEVICE
Intervention: dPR and FFR
Description: OpSens non-hyperemic dPR and/or OpSens FFR
Study: NCT06253234

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: personalized dendritic cell injection ZSNeo-DC1.1
Description: Sequence A: For the first 3 cycles, 1 week as a dosing cycle, the next 3 cycles, 3 weeks as a dosing cycle, a total of 6 dosing cycles Sequence B: For the first 3 cycles, 1 week as a dosing cycle, the next 3 cycles, 2 weeks as a dosing cycle, a total of 6 dosing cycles

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: personalized dendritic cell injection ZSNeo-DC1.1
Description: Sequence A: For the first 3 cycles, 1 week as a dosing cycle, the next 3 cycles, 3 weeks as a dosing cycle, a total of 6 dosing cycles Sequence B: For the first 3 cycles, 1 week as a dosing cycle, the next 3 cycles, 2 weeks as a dosing cycle, a total of 6 dosing cycles
Study: NCT05269641

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food: whole almonds
Description: 60g of whole almonds will be consumed daily.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Food: non-nut snack
Description: A non-nut snack will be consumed daily.
Study: NCT05079867

Intervention type: DEVICE
Intervention: Cochlear implantation
Description: Electrode surgically implanted in patient's cochlea to improve hearing

Intervention type: DEVICE
Intervention: Cochlear implantation
Description: Electrode surgically implanted in patient's cochlea to improve hearing
Study: NCT05273658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis
Description: Participants will smoke a cannabis cigarette ad libitum as per their usual routine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis
Description: Participants will smoke a cannabis cigarette ad libitum as per their usual routine

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cannabis
Description: Participants will smoke a cannabis cigarette ad libitum as per their usual routine
Study: NCT06124274

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Protein tracer drink
Description: Subjects will be fed a mixed-macronutrient beverage at rest (0.75g/kg lean body mass of carbohydrates; 0.125g/kg lean body mass of protein). Amino acid composition of the protein will be modelled off the composition of egg. Leucine content will be enriched to 5% with \[13 Carbon(13C)\]-leucine.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Protein tracer drink
Description: Subjects will be fed a mixed-macronutrient beverage at rest (0.75g/kg lean body mass of carbohydrates; 0.125g/kg lean body mass of protein). Amino acid composition of the protein will be modelled off the composition of egg. Leucine content will be enriched to 5% with \[13 Carbon(13C)\]-leucine.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Protein tracer drink
Description: Subjects will be fed a mixed-macronutrient beverage at rest (0.75g/kg lean body mass of carbohydrates; 0.125g/kg lean body mass of protein). Amino acid composition of the protein will be modelled off the composition of egg. Leucine content will be enriched to 5% with \[13 Carbon(13C)\]-leucine.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Protein tracer drink
Description: Subjects will be fed a mixed-macronutrient beverage at rest (0.75g/kg lean body mass of carbohydrates; 0.125g/kg lean body mass of protein). Amino acid composition of the protein will be modelled off the composition of egg. Leucine content will be enriched to 5% with \[13 Carbon(13C)\]-leucine.
Study: NCT04905849

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adaptive Cognitive Control Trainer (ACCT)
Description: Module 1: Attention=\> This module demands an active scan of the screen in search for a target, much like traditional visual search tasks. Participants quickly identify the direction that a probe target is facing (up, down, left, right), and are aided by the presence of directional cue indicating where the location of the target will appear.~Module 2: Goal Management=\> Requires participants to rapidly switch their focus based on distinct rules. Participants are presented with exemplar objects along with a target, and are asked to indicate which exemplar presented is most like the target.~Module 3: Working Memory=\> Engages spatial working memory resources similar to the Corsi block task. Participants memorize the location of objects on screen followed by a 5-7 second delay period, with a correct response leading to a greater number of potential targets to be memorized on the next trial (and vice versa).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Control App
Description: The app used here is undergoing expectancy-matching at the present time, will be updated with the final app characteristics when completed out of a list of several possibilities
Study: NCT04639713

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tixel 2
Description: Thermo-mechanical technology for fractional treatment of human skin. Dermal heating and coagulative effect that occur during the treatment session provide dermal remodeling and collagen restructuring that promote wrinkles appearance improvement.
Study: NCT05553899

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: PET-MRI
Description: magnetic resonance imaging with positron emission tomography scanning using the tracer 18F-FDG
Study: NCT05273658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis
Description: Participants will smoke a cannabis cigarette ad libitum as per their usual routine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabis
Description: Participants will smoke a cannabis cigarette ad libitum as per their usual routine
Study: NCT04754126

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Amazing Me
Description: The Amazing Me Program is an evidence-based program designed to help children between the ages of 9 and 11 build self-esteem, body confidence, and eliminate weight-based bullying and teasing. This school-based curriculum satisfies national educational health requirements and provides tools for teachers to implement in 4th and 5th grade classrooms.
Study: NCT05676086

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: indoor light intervention
Description: Persons allocated to the indoor light intervention arm will be given a lamp to be placed at home with specific instructions to install it in a room where they spend most of their time, in order to supplement the existing indoor lighting. Thus, all people of the intervention arm will be equipped with the LUMIE Halo lamp. Utilizing both warm-white and cool-white LEDs, Lumie Halo delivers 10,000 lux at 20 cm at maximum brightness in Day Mode. The touch slider allows the user to adjust the brightness while mixing the color temperature of the light.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: no indoor light
Description: Persons allocated to the control group will receive no indoor light supplementation and will undergo assessment procedures only. Exposure to the outdoor intervention will be taken into account in the analysis in three ways, (1) by locating the distance between people's home and the modified outdoor light, (2) by a question about the awareness of the change in outdoor light, timing, and duration of exposure and what they think of it, and (3) by recording the amount of light exposure over the 24 hours during two weeks at baseline and after the 1-year light interventions
Study: NCT05273658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Participants will ingest alcohol to achieve the target breath alcohol level

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Participants will ingest alcohol to achieve the target breath alcohol level

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Alcohol
Description: Participants will ingest alcohol to achieve the target breath alcohol level

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Participants will ingest alcohol to achieve the target breath alcohol level

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alcohol
Description: Participants will ingest alcohol to achieve the target breath alcohol level
Study: NCT05568498

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: Oral probiotic delivered in powdered form.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral placebo delivered in powdered form.
Study: NCT05161754

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hemostasis
Description: Hot hemostasis include bipolar and monopolar diathermy. Cold hemostasis include surgical knotting of the tonsil pillar and compression.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hemostasis
Description: Hot hemostasis include bipolar and monopolar diathermy. Cold hemostasis include surgical knotting of the tonsil pillar and compression.
Study: NCT06168565

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent pneumatic compression (AirRelax)
Description: Moderate pressure (around 80mmHg); high pressure (around 200mmHg), both applied on the lower-limbs

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent pneumatic compression (AirRelax)
Description: Moderate pressure (around 80mmHg); high pressure (around 200mmHg), both applied on the lower-limbs