TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05768685

Intervention type: BEHAVIORAL
Intervention: Affective touch paradigm
Description: Affective touch paradigm: experimental stimuli will include the touch of a soft cosmetic, a hand, which will be both expected to resemble affective pleasant stimulations, and a plastic stick with a rounded tip, as a control (non-affective) condition. Two speeds of stimulation will be adopted i) slow affective stimuli delivered at 3 cm/s and fast non-affective stimuli, delivered at non-optimal speed (18 cm/s). An imagery version of the task will be also administered: blindfolded participants will be asked to image the touches on their left forearm. After each (actual or imagined) tactile stimulus, individuals will rate the experience level of pleasantness. As part of the protocol, they will fill out two psychological questionnaires, assessing the level of social anhedonia and the amount and characteristics of the lifespan experiences of affective touch inclose relationships.

Intervention type: BEHAVIORAL
Intervention: Affective touch paradigm
Description: Affective touch paradigm: experimental stimuli will include the touch of a soft cosmetic, a hand, which will be both expected to resemble affective pleasant stimulations, and a plastic stick with a rounded tip, as a control (non-affective) condition. Two speeds of stimulation will be adopted i) slow affective stimuli delivered at 3 cm/s and fast non-affective stimuli, delivered at non-optimal speed (18 cm/s). An imagery version of the task will be also administered: blindfolded participants will be asked to image the touches on their left forearm. After each (actual or imagined) tactile stimulus, individuals will rate the experience level of pleasantness. As part of the protocol, they will fill out two psychological questionnaires, assessing the level of social anhedonia and the amount and characteristics of the lifespan experiences of affective touch inclose relationships.
Study: NCT06418191

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupressure
Description: Acupressure is a technique that involves applying pressure to specific points on the body. It is based on the same principles as acupuncture but uses pressure from fingers, palms, elbows, or specialized devices instead of needles.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Acupressure
Description: Acupressure is a technique that involves applying pressure to specific points on the body. It is based on the same principles as acupuncture but uses pressure from fingers, palms, elbows, or specialized devices instead of needles.
Study: NCT04967235

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Exercise-based Cardiac Rehabilitation Session
Description: This session will be composed of:~I.10 minutes of initial rest in the supine position; II. 15 minutes of warm-up through stretching and global exercises; III. 30 minutes of treadmill aerobic exercise at an intensity of 60-80% of the heart rate reserve for those without diabetes Mellitus and 40-70% of the heart rate reserve for those diagnosed with diabetes mellitus; IV. 1 minute passive recovery in orthostatic position; V. 30 minutes of passive recovery in the supine position.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dance-based Cardiac Rehabilitation Session
Description: I.10 minutes of initial rest in the supine position; II. 15 minutes of warm-up through stretching and global exercises; III. 30 minutes of dance therapy. The intensity of the choreography will be set at the same range as the conventional exercise-based session. (60-80% of the heart rate reserve for those without diabetes Mellitus and 40-70% of the heart rate reserve for those diagnosed with diabetes mellitus); IV. 1 minute passive recovery in orthostatic position; V. 30 minutes of passive recovery in the supine position.
Study: NCT04690595

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BAFFR-CAR T cells
Description: First-in-human trial examining the safety and preliminary efficacy of BAFFR-CAR T cells in participants with r/r B-ALL
Study: NCT06117293

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mosaic
Description: 1550 Fractional Laser System
Study: NCT05183165

Intervention type: OTHER
Group type: OTHER
Intervention: Patients with Wilson's disease declaring pregnancy,
Description: Blood and urine biological assessment Dietary assessment
Study: NCT06223399

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Imaging-based programming
Description: Preferred contact point(s) and settings for DBS programming will be determined based on the visualization of the electrodes in the patient-specific anatomy and the volume of tissue activated (VTA; i.e., the tissue enclosed within an iso-surface of the activation function). This will be determined with help of the software program Brainlab with the GUIDE XT module.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Threshold assessment-based programming
Description: The preferred contact point(s) and settings for DBS programming will be determined according to current clinical practice. During the threshold assessment, the amount of electrical current needed to generate symptomatic improvement and the amount of electrical current needed to generate adverse-effects are determined for every contact point of both DBS leads by increasing current with 0.5 mA steps from 0 to approximately 5.0 mA. With each step, severity of Parkinson symptoms and presence of possible adverse-effects are assessed. For each side (i.e., left and right), the contact point with the most favorable trade-off between clinical improvement and adverse effects will be used for stimulation.
Study: NCT04777864

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Decision Aid
Description: In addition to usual care, participants (parents and adolescents) receive the newly developed decision aid prior to their clinic visit(s). Clinicians receive a summary to review and use to help facilitate the decision making process.
Study: NCT06236867

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: KaleidoscopeGroup
Description: The group consists of 34 people. Pain level was measured during 3 dialysis sessions.In order for the patients in the kaleidoscope group to recognize the device and increase their compliance during the procedure, a practice was performed using the device before the AVF cannulation procedure. Kaleidoscope application was performed during cannulation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ice Application Group
Description: The group consists of 34 people. Pain level was measured during 3 dialysis sessions. Before, during and after AVF cannulation, VAS pain scores will be evaluated after cannulation without any intervention.Ice application application was made with non-melting ice molds to the area where the index finger and thumb of the hand with fistula are joined (HOKU point)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Group
Description: The group consists of 34 people. Pain level will be measured during 3 dialysis sessions. In the control group, the vital signs of the patients before AVF cannulation will be recorded.
Study: NCT05354388

Intervention type: PROCEDURE
Intervention: Resection surgery of gastrointestinal stromal tumor
Description: oral administration of Ripretinib 150 mg QD. Resection of gastrointestinal stromal tumors was performed in patients who achieved PR or SD
Study: NCT05773118

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: orthokeratology lens
Description: Subjects will wear orthokeratology lens at night. Axial length elongation over a period of 12-month will be recorded.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: multifocal soft contact lens
Description: Subjects will wear multifocal soft contact lens during the day time. Axial length elongation over a period of 12-month will be recorded.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Single vision spectacles
Description: Subjects will wear single vision spectacles during the day. Axial length elongation over a period of 12-month will be recorded.
Study: NCT05841355

Intervention type: OTHER
Group type: OTHER
Intervention: Educate
Description: Education sessions

Intervention type: OTHER
Group type: OTHER
Intervention: Empower
Description: Empowerment sessions
Study: NCT05938257

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TMJ discopexy
Description: Arthroscopic versus open TMJ discopexy
Study: NCT06472817

Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study: NCT05608564

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Piperacillin and Tazobactam in gel form
Description: After non-surgical periodontal treatment, the test group will receive local antibiotics.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin and Metronidazole
Description: After non-surgical periodontal treatment, the control group will receive systemic antibiotics.
Study: NCT06179966

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dance group
Description: The application will be taught to the participants' spouses by the researcher after they are admitted to labor, and the spouses will be asked to do it to the participants at regular intervals.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage group
Description: After admission to travaya, the researcher will teach the pregnant woman's husband practically and the spouses will massage the participants' backs at certain intervals.
Study: NCT05914519

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ejaculatory Preserving Transurethral resection of prostate
Description: Transurethral resection of prostate with preservation of 1cm safety area above verumontanum and without paracollicular digging

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Transurethral Resection of prostate
Description: Transurethral resection of prostate including whole adenoma till the capsule.
Study: NCT05899842

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Protein pump inhibitor therapy systematically
Description: Lansoprazole 30mg once per day
Study: NCT06457828

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-corticosteroid injection
Description: no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Non-corticosteroid injection
Description: no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Corticosteroid injection
Description: infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Corticosteroid injection
Description: infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Study: NCT05390970

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Platelet-rich plasma injection
Description: Injection of autologous platelet-rich plasma into the anterior vaginal wall

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Platelet-rich plasma injection
Description: Injection of autologous platelet-rich plasma into the anterior vaginal wall
Study: NCT05791539

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: Patients will be divided into 2 groups group 1 will receive US-guided ESPB and group 2 will receive US-guided ESPB + US-guided Retrolaminar plain block before induction of GA.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: Patients will be divided into 2 groups group 1 will receive US-guided ESPB and group 2 will receive US-guided ESPB + US-guided Retrolaminar plain block before induction of GA.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: erector spinae plane block + retrolaminar block
Description: Patients will be divided into 2 groups group 1 will receive US-guided ESPB and group 2 will receive US-guided ESPB + US-guided Retrolaminar plain block before induction of GA.
Study: NCT05025176

Intervention type: DEVICE
Intervention: Non invasive arterial pressure monitoring
Description: Non invasive arterial pressure monitoring
Study: NCT05416021

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dapivirine
Description: dapivirine vaginal ring

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dapivirine
Description: dapivirine vaginal ring
Study: NCT06196255

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: anti-FcRL5 CAR-T
Description: anti-FcRL5 autologous CAR T cells will be infused at a dose ranging from 1 - 2 x 10\^6/kg CAR+ T cells after receiving lymphodepleting chemotherapy.
Study: NCT05856773

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Proton Therapy
Description: Pencil Beam Scanning (PBS)

Intervention type: RADIATION
Group type: OTHER
Intervention: Proton Therapy
Description: Pencil Beam Scanning (PBS)
Study: NCT05025644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pre and post-CPB Drug: Dobutamine Hydrochloride
Description: * Pre-CPB provocation test with DBT stress test will be started (starting at 5 mcg/kg/min, increasing every 3 min, to 10, 15 and 20 mcg/kg/min) until a PG ≥ 50mmHg is achieved (DBT peak dose). The DBT peak dose (DBT-pd) will be recorded.~* Post-CPB provocation test at the DBT-pd achieved preoperatively.
Study: NCT05970965

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biological sampling
Description: - Saliva and blood sampling
Study: NCT05025644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Post-CPB Drug: Dobutamine Hydrochloride
Description: * Pre-CPB no intervention will be required.~* Post-CPB provocation test with DBT stress test will be started (starting at 5 mcg/kg/min, increasing every 3 min, to 10, 15 and 20 mcg/kg/min) or until postoperative provocable PG is \>16 mmHg.
Study: NCT05300009

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: topical methotrexate hydrogel 1% coupled with microneedling.
Description: Microneedling will be performed on each wart for a maximum 5 lesions per patient using dermapen (Ostar rechargeable dermapen, OB-DG 03N, Ostar Beauty Sci-Tech Co, Beijing, China) supplied with 12 needles arranged in rows. The penetration depth was adjusted at 2-mm, endpoint was pinpoint bleeding and the dermapen will be held by the hand in a vertical direction on the wart. Then topical methotrexate 1% gel will be applied on the lesions every session.
Study: NCT05258786

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pre-labor ultrasound as a visual biofeedback device for maternal pushing education and pelvic floor training
Description: 1. Ultrasound examination with the screen turned to the provider will assess the bladder movements at rest and during contraction of the pelvic floor and fetal head descent at rest and during pushing.~2. The provider will turn the screen to the patient and explain the anatomical landmarks: bladder, fetal head, birth canal direction.~3. A repeat of the first stage (1) with the screen turned to the patient: the biofeedback process. Bladder displacement will serve as a marker of pelvic floor contraction, and the delta in the progression angle will serve as a marker for effective pushing.~4. Finally, the provider will turn the screen again from the patient and repeat the first stage.
Study: NCT05085587

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Test
Description: 2 inhalations of Test and Reference product in each study period

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Reference
Description: 2 inhalations of Test and Reference product in each study period
Study: NCT06229600

Intervention type: OTHER
Intervention: Standard rehabilitation
Description: Respiratory rehabilitation

Intervention type: OTHER
Intervention: Standard rehabilitation
Description: Respiratory rehabilitation

Intervention type: OTHER
Intervention: Standard rehabilitation
Description: Respiratory rehabilitation

Intervention type: OTHER
Intervention: Standard rehabilitation
Description: Respiratory rehabilitation

Intervention type: OTHER
Intervention: Standard rehabilitation
Description: Respiratory rehabilitation

Intervention type: OTHER
Intervention: Standard rehabilitation
Description: Respiratory rehabilitation
Study: NCT05291845

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candida antigen vaccine
Description: we will study the efficacy and safety of agent in the treatment of multiple warts, we will follow up the recurrence rate of each group

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candida antigen vaccine
Description: we will study the efficacy and safety of agent in the treatment of multiple warts, we will follow up the recurrence rate of each group

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bivalent HPV vaccine
Description: we will study the efficacy and safety of agent in the treatment of multiple warts, we will follow up the recurrence rate of each group

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bivalent HPV vaccine
Description: we will study the efficacy and safety of agent in the treatment of multiple warts, we will follow up the recurrence rate of each group
Study: NCT05265195

Intervention type: OTHER
Intervention: Mixed Methods study
Description: Mixed Methods study

Intervention type: OTHER
Intervention: Mixed Methods study
Description: Mixed Methods study

Intervention type: OTHER
Intervention: Mixed Methods study
Description: Mixed Methods study

Intervention type: OTHER
Intervention: Mixed Methods study
Description: Mixed Methods study

Intervention type: OTHER
Intervention: Mixed Methods study
Description: Mixed Methods study

Intervention type: OTHER
Intervention: Mixed Methods study
Description: Mixed Methods study
Study: NCT05830006

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microfat grafting
Description: Microfat grafting in cleft lip nasal deformities
Study: NCT05694091

Intervention type: OTHER
Intervention: Collecting clinical data, blood gas data, Magnetic Resonance Spectroscopy (MRS) data and blood,urine, and feces sample
Description: Collecting clinical data(before induction of anesthesia and first day after surgery), blood gas data(before induction of anesthesia and first day after surgery) ，MRS data (not more than 24h after surgery）and blood,urine, and feces sample （before induction of anesthesia and first day, third day and 7th day after surgery）

Intervention type: OTHER
Intervention: Collecting clinical data, blood gas data, Magnetic Resonance Spectroscopy (MRS) data and blood,urine, and feces sample
Description: Collecting clinical data(before induction of anesthesia and first day after surgery), blood gas data(before induction of anesthesia and first day after surgery) ，MRS data (not more than 24h after surgery）and blood,urine, and feces sample （before induction of anesthesia and first day, third day and 7th day after surgery）
Study: NCT04891588

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Switching the preserved prostaglandin analog-timolol FC to Fixalpost (preservative free prostaglandin analog-timolol FC)
Description: switching preserved prostaglandin analog- timolol FC (fixed combination) in the period of three months in patients with ocular hypertension and open angle glaucoma who exhibit ocular surface disease (OSD) signs and symptoms to an equally effective and safe preservative - free (PF) latanoprost - timolol FC (Fixalpost).~form: preservative free latanoprost - timolol fix combination (50 micrograms/ml latanoprost + 5 mg/ml timolol), ocular solution dosage: once daily, at 8.00 p.m. duration: 3 months
Study: NCT05105165

Intervention type: DIAGNOSTIC_TEST
Intervention: Enzyme linked immunosorbent assay
Description: Determination of serum β 1-aa content

Intervention type: DIAGNOSTIC_TEST
Intervention: Enzyme linked immunosorbent assay
Description: Determination of serum β 1-aa content

Intervention type: DIAGNOSTIC_TEST
Intervention: Enzyme linked immunosorbent assay
Description: Determination of serum β 1-aa content
Study: NCT05381935

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ES014
Description: ES014 is administered via intravenous infusion, once every 14 days, every 28 days as a treatment cycle for a maximum treatment duration per patient of 2 years.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ES014
Description: ES014 is administered via intravenous infusion, once every 14 days, every 28 days as a treatment cycle for a maximum treatment duration per patient of 2 years.
Study: NCT06084858

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dialysate bicarbonate modification
Description: Dialysate bicarbonate prescription will be modified from low (27 mmol/l) to high (37 mmol/l) in a step-wise fashion
Study: NCT06013254

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: sour liquid
Description: applying lemon juice
Study: NCT05909514

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PelvicSense(R)
Description: PelvicSense® is a home-based physiotherapy program integrating multiple techniques, including relaxation, breathing, stretching, strengthening and at-home manual therapy. This program also educates participants about the anatomy and physiology of the pelvis and teaches strategies to strengthen the mind-muscle connection to the pelvis.
Study: NCT05300009

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Liquid nitrogen
Description: The wart is frozen for 10 to 30 seconds until a 1- to 2-mm ice ball halo surrounds the targeted area.~The sessions were performed every 2 week until complete clearance for a maximum of six sessions.
Study: NCT05127876

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ondansetron 4 MG
Description: Ondansetron 4mg was given over 1 min, 5 min before spinal anesthesia

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ondansetron 8mg
Description: Ondansetron 8mg was given over 1 min, 5 min before spinal anesthesia

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EPHEDrine 10 Mg/mL-NaCl 0.9% Intravenous Solution
Description: Ephedrine 10mg was given over 1 min, 5 min before spinal anesthesia

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 10 mL normal saline
Description: 10 mL normal salinwe 0.9% was given over 1 min, 5 min before spinal anesthesia