TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06600464

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: The thickness of the thenar eminence muscles (longitudinal thickness of the first dorsal interosseous muscle (FDI), abductor pollicis brevis (APB), and opponens pollicis (OPP)) was measured using musculoskeletal ultrasound.

Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: The thickness of the thenar eminence muscles (longitudinal thickness of the first dorsal interosseous muscle (FDI), abductor pollicis brevis (APB), and opponens pollicis (OPP)) was measured using musculoskeletal ultrasound.

Intervention type: OTHER
Intervention: Assessment of Muscle Strength in Both Hands
Description: Muscle strength in both hands was evaluated using grip strength measured with a dynamometer (Jamar Hydraulic Hand Dynamometer, Nottinghamshire, UK)

Intervention type: OTHER
Intervention: Assessment of Muscle Strength in Both Hands
Description: Muscle strength in both hands was evaluated using grip strength measured with a dynamometer (Jamar Hydraulic Hand Dynamometer, Nottinghamshire, UK)

Intervention type: OTHER
Intervention: Assessment of Pain Threshold
Description: Pressure pain threshold (PPT) for painful and non-painful finger joints was assessed using a hand-held algometer

Intervention type: OTHER
Intervention: Assessment of Pain Threshold
Description: Pressure pain threshold (PPT) for painful and non-painful finger joints was assessed using a hand-held algometer
Study: NCT06407921

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Whole Body Vibration
Description: On vibration plate pate child will do kneeling, and one leg standing, standing horizontally or vertically. Along routine physical therapy such as stretching activities to keep up muscle elasticity particularly Achilles tendon, hamstring muscles, hip flexors and adductors, shoulder internal rotators, elbow and wrist flexors, pronators, and ulnar deviators, each stretch will be given for 30 seconds with 3 repetitions.Strength training to hip flexor, knee extensor, and ankle dorsiflexors for 15 minutes 3 times a week for 8 weeks. Session will be of 30 minutes

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BOSU ball
Description: Exercises such as (1) standing on a BOSU ball while throwing and catching a ball (2) 1-legged standing (affected leg) on the BOSU ball while throwing and catching a ball with therapist support; and (3) small jumps on the BOSU ball. Three sets of 6 repetitions for each exercise will be perform every 2 weeks up to a maximum of 10 repetitions if the participants were still able to perform the training easily. Total dose of balance training in 1 session will be 15 minutes
Study: NCT06600867

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Tooth mobility assessment
Description: The examiner, holding the instruments (two clinical mirror handles), will apply labial/lingual or labial/palatal displacement movements using the subjective technique, just as routinely done. Using the endodontic spacer and the stop, the deflection will be measured in millimeters. Subsequently, the examiner, with the instruments in hand (tensiometer and dynamometer), will apply labial/lingual and labial/palatal displacement movements, determining the force required to achieve the same displacement previously established by the subjective method (reference/limit of displacement).
Study: NCT06700135

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: sensorimotor stimulation program sessions
Description: The study group, consisting of 15 neonates, received traditional medical treatment along with sensorimotor stimulation program sessions. These sessions included oral stimulation protocol, Tactile/Kinesthetic (T/K) intervention, feeding position, and oral support.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sensorimotor stimulation program sessions
Description: The study group, consisting of 15 neonates, received traditional medical treatment along with sensorimotor stimulation program sessions. These sessions included oral stimulation protocol, Tactile/Kinesthetic (T/K) intervention, feeding position, and oral support.
Study: NCT06698653

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SAM device (experimental): a removable structure, fixed to the horizontal frame of the medical bed, equipped with a handle to assist the sitting-up process
Description: The patients will use the experimental device during 7 days straight as well as the comparator during 7 days straight. The order in which they will use each device will depend on the groupe they have been randomized in : - Groupe 1 : Experimental device during 7 days then control device during 7 days - Groupe 2 : Control device during 7 days then experimental device during 7 days

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Over bed pole hoist (control device)
Description: The patients will use the experimental device during 7 days straight as well as the comparator during 7 days straight. The order in which they will use each device will depend on the groupe they have been randomized in : - Groupe 1 : Experimental device during 7 days then control device during 7 days - Groupe 2 : Control device during 7 days then experimental device during 7 days
Study: NCT06700824

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OTR4132
Description: OTR4132 is a new ReGeneraTing Agent (RGTA®) which is a polymer of glucose (α-1,6 bounds, i.e. dextran backbone) engineered to mimic heparan sulphate (HS) in all three mechanical functions (extracellular matrix scaffold element, protector of matrix pro-teins and cellular communication peptides storage sites) but differ from HS by their resistance to glycanases. OTR4132 allows a restoration of the matrix architecture which secondarily facilitates cell survival and recovery at the site of injury.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: saline solution
Study: NCT05856422

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Respiratory rate measure based on PPG
Description: Testing was conducted under normal office environment conditions. Each subject was connected to the reference EtCO2 monitor (GE Datex-Ohmeda) and the Device Under Test, the Gabi SmartCare Gabi Band. A waveform collected from an EtCO2 measurement was used to determine performance of respiratory rate metrics. Each subject was given a nasal cannula that allowed for measurement of the EtCO2 respiratory rate.~The reference respiratory rate was measured simultaneously with the Device Under Test. Data was marked for stable quiet periods that were useable for analysis.
Study: NCT06702072

Intervention type: DEVICE
Intervention: Endobronchial valve treatment
Description: Endobronchial valve treatment
Study: NCT06705660

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: WEB-based progressive relaxation training
Description: WEB-based progressive relaxation training will be given for 8 weeks, 2 days a week for 30-45 minutes (16 sessions), following the menstrual cycles of women. Measurements will be taken before and after (at the end of) the intervention. Measurements will be taken 4 weeks after the next menstrual cycle to ensure follow-up.~Progressive relaxation training is an easy-to-learn, non-invasive and side-effect free method. PGE beginners will be trained for at least 30 minutes and practitioners who have learned the basics of the method will be trained to introduce PGE for 15 minutes. Prior to the PGE, individuals will be informed that they should not come overly hungry or overly full (eating should be finished 2 hours before), wear loose and comfortable clothes, avoid clothes that tightly wrap the abdomen (pants, dresses, belts), remove contact lenses, glasses, jewelry and tight shoes. PGE will be administered in a quiet, comfortable and dimly lit place. Women will perform PCI in the supine posit

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The WEB-based lifestyle interventions
Description: The WEB-based lifestyle interventions will be administered to women by monitoring their menstrual cycles for 8 weeks, with sessions held twice a week for 30-45 minutes each (totaling 16 sessions). Measurements will be taken both before the intervention and after its completion. An additional measurement will be conducted during the following menstrual cycle, 4 weeks later, to ensure follow-up.In this study, telehealth and counseling services will be provided. Through telehealth and counseling, women will have the opportunity to communicate online with healthcare professionals and receive guidance on health goals, nutrition, exercise, and stress management
Study: NCT06705738

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: SUPOL
Description: Supplement containing Olive Oil Polyphenol with the main substance being Oleocanthal (SUPOL), 2 capsules twice a day (4 capsules total) for 12 months.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: SUPOL
Description: Supplement containing Olive Oil Polyphenol with the main substance being Oleocanthal (SUPOL), 2 capsules twice a day (4 capsules total) for 12 months.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary Pattern: MeDi
Description: Adherance to Mediterranean dietary pattern to be followed for 12 months.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Dietary Pattern: MeDi
Description: Adherance to Mediterranean dietary pattern to be followed for 12 months.
Study: NCT06705361

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transparent Radial Artery Band (Screw-Type)
Description: The researcher will randomly assign patients undergoing radial arterial line removal after open heart surgery into four groups: ice-bag pressure, transparent radial band compression device (screw type), transparent radial band compression device (air type), and control group. The researcher will assign specific card colors to each group: white for the control group, yellow for the ice-bag pressure group, pink for the Transparent Radial Band Compression Device - Screw Type group, and green for the Transparent Radial Band Compression Device - Air Type group. The researcher will place all these cards in a container, allowing the participant to select their preferred color, and then apply the intervention separately to each group.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transparent Radial Artery Band (Screw-Type)
Description: The researcher will randomly assign patients undergoing radial arterial line removal after open heart surgery into four groups: ice-bag pressure, transparent radial band compression device (screw type), transparent radial band compression device (air type), and control group. The researcher will assign specific card colors to each group: white for the control group, yellow for the ice-bag pressure group, pink for the Transparent Radial Band Compression Device - Screw Type group, and green for the Transparent Radial Band Compression Device - Air Type group. The researcher will place all these cards in a container, allowing the participant to select their preferred color, and then apply the intervention separately to each group.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transparent Radial Artery Band (Screw-Type)
Description: The researcher will randomly assign patients undergoing radial arterial line removal after open heart surgery into four groups: ice-bag pressure, transparent radial band compression device (screw type), transparent radial band compression device (air type), and control group. The researcher will assign specific card colors to each group: white for the control group, yellow for the ice-bag pressure group, pink for the Transparent Radial Band Compression Device - Screw Type group, and green for the Transparent Radial Band Compression Device - Air Type group. The researcher will place all these cards in a container, allowing the participant to select their preferred color, and then apply the intervention separately to each group.
Study: NCT06706427

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NGGT001
Description: Using a recombinant adeno-associated virus (AAV) vector to deliver the gene CYP4V2 via subretinal injection for the treatment of crystalline retinal degeneration.
Study: NCT06705803

Intervention type: PROCEDURE
Intervention: Prostate Ablation
Description: Patients with prostate cancer undergoing prostate ablation for the management of prostate cancer.
Study: NCT06705478

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pramipexole ER
Description: Tablets self-administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram
Description: Tablets self-administered orally
Study: NCT06705933

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Core stability exercise
Description: Lumbo-pelvic stabilizing exercises (posterior pelvic tilt, bilateral hip abduction, bilateral knee raise, bridging, hip shrugging) will be performed three times per week for eight weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core stability exercise
Description: Lumbo-pelvic stabilizing exercises (posterior pelvic tilt, bilateral hip abduction, bilateral knee raise, bridging, hip shrugging) will be performed three times per week for eight weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial release
Description: The participants will receive myofascial release technique for 20 min for 3 times per week for 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial release
Description: The participants will receive myofascial release technique for 20 min for 3 times per week for 8 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotaping
Description: The participants will receive Kinesio-Taping over the sacroiliac joint and the hip region. Following a test trial of a small patch for 24 hours, they will be instructed to keep the tape on for 48 hours (it will be replaced after 48 hours) . It will be applied for 8 weeks.
Study: NCT06704880

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rehabilitation
Description: children in the CIMT group will RECIEVE lower limb CIMT for the non-hemiplegic limb using whole leg orthosis. Children in cross-education group will receive strengthening training for the non-hemiplegic lower limb

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rehabilitation
Description: children in the CIMT group will RECIEVE lower limb CIMT for the non-hemiplegic limb using whole leg orthosis. Children in cross-education group will receive strengthening training for the non-hemiplegic lower limb
Study: NCT06706414

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Denosumab (Prolia)
Description: Subcutaneous injection with 60 mg Denosumab once
Study: NCT06705751

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Autonomic response in AAOCA
Description: Autonomic regulation sub-analysis: Autonomic control will be evaluated in a population prospectively recruited.~Thirty-eight subjects with Anomalous Aortic Origin of a Coronary Artery (AAOCA) will undergo an active standing test. For this prospective sample, demographic and clinical data, as well as DICOM images from previously conducted diagnostic CT angiographies (CTAs) for AAOCA, will also be collected. These data will be utilized to assess the final functionality of the online platform before its public launch.~The patients will be subjected to the active standing test to elicit an autonomic response, with results compared to reference normal values. During this examination, the following data will be collected: continuous ECG, non-invasive blood pressure, and respiratory measurements in both supine and prone positions.
Study: NCT06705179

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Behavioral task performance
Description: Measures of performance on behavioral tasks
Study: NCT06705543

Intervention type: GENETIC
Group type: ACTIVE_COMPARATOR
Intervention: multi-omics genetic analyses included exome
Description: Genetic analysis will be carried out on amniotic fluid from the volume collected as part of the by obstetricians working in the fetal medicine unit. These genetic analyses will include :~* Study of free RNA circulating in the LA,~* Methylome study.~* Trio exome study (parents-fetus).

Intervention type: GENETIC
Group type: PLACEBO_COMPARATOR
Intervention: multi-omics genetic analyses
Description: Genetic analysis will be carried out on amniotic fluid from the volume collected as part of the by obstetricians working in the fetal medicine unit; These genetic analyses will include :~* Study of free RNA circulating in the LA,~* Methylome study.
Study: NCT06705114

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: complete denture
Description: Each patient received a newly constructed conventional complete denture with optimal denture extension and lingualized balanced occlusal concept

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: implant overdenture
Description: Two dental implants were inserted in the patient's mandibular arch at the canine region using guided surgery and a delayed loading protocol.After 3-4 months, the dental implants were exposed and ball abutments were screwed into the implants. The housing of the ball attachments were incorporated into the fitting surface of the mandibular denture using a direct pick-up technique (Fig. 1B). The mandibular overdenture was then inserted into the patient's mouth and occlusal adjustment was done using articulating paper to remove any occlusal interferences. Follow-up visits were scheduled.
Study: NCT06705283

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: yoga and home exercise
Description: The intervention period for the study was determined as 6 weeks. It has been decided that yoga practice will be done 3 times a week for 45 minutes.~Poses to be practiced in the yoga group:~1. Tadasana (mountain pose)~2. Utkatasana (chair pose)~3. Trikonasana (triangle pose)~4. Malasana (squat pose):~5. Viparita Karani Variation (legs up the wall pose)~6. Salamba Set Bandhasana (supported bridge pose)~7. Supta Baddha Konasana (reclining bound angle pose)~8. Savasana (dead pose)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: whole body vibration training and home exercise
Description: A total of 40-45 minutes of training was planned for WBVT, including warm-up (10 minutes), active phase (25-30 minutes) and cooling phase (5 minutes).

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: home exercise group
Description: Pelvic floor muscle training will be done in the home exercise group. This training will be done in the form of slow and fast contractions of the pelvic floor muscles in supine, chin up, sitting, squat and standing positions.
Study: NCT04467983

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Denosumab Injection
Description: Denosumab alone: 3 injections of Denosumab at appropriate times, separated by no more than 7 months from the last treatment.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Denosumab Injection
Description: Denosumab alone: 3 injections of Denosumab at appropriate times, separated by no more than 7 months from the last treatment.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Abaloparatide
Description: Combination therapy: 3 injections of Denosumab at appropriate times, separated by no more than 7 months from the last treatment, with added abaloparatide 80 mcg subcutaneously daily, started within 6 months of the last denosumab treatment, for a total of 18 months.
Study: NCT05241873

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-451
Description: BLU-451 will be administered orally by tablet QD or BID on a 21-day treatment cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin will be administered intravenously (IV) on Day 1 of each cycle (every 3 weeks) for 4 to 6 cycles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Pemetrexed will be administered prior to carboplatin as an IV infusion on Day 1 of each cycle (every 3 weeks)
Study: NCT06464458

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: management on hydroxyurea by therapeutic pharmacological monitoring
Description: HU dose adaptation according:~* HU AUC with a target AUC and subject to haematological tolerance.~* T2H (at V2, V3, V4), subject to haematological tolerance.
Study: NCT05622734

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VOCALE LBD+
Description: Intervention employs a web-based platform that allows participants to engage asynchronously in an eight-week online intervention involving didactic training, peer-to-peer support, and moderated problem-solving skill enactment.
Study: NCT06173830

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: radiofrequency ablation
Description: 34 patients with chronic knee osteoarthritis meeting the criteria will undergo ultrasound-guided radiofrequency ablation of the genicular nerve.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: physical therapy
Description: 34 patients with chronic knee osteoarthritis meeting the criteria will undergo 10 sessions of physical therapy.
Study: NCT06088888

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TGRX-678
Description: Participants are given TGRX-678 tablets orally, once daily, at one of the dose levels as pre-determined for the dose escalation sequence or expansion cohorts.
Study: NCT04697667

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Supervised exercise program

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Supervised exercise program

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PRP
Description: Intra-articular PRP injections to knee joint

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PRP
Description: Intra-articular PRP injections to knee joint