TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05374304

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Case/Worst Case (BC/WC) Geriatric Oncology (GeriOnc) communication tool
Description: The BC/WC framework guides clinicians to present a choice between two options and uses scenario planning (narrative descriptions of plausible outcomes that acknowledge uncertainty) to describe the best, worst, and most likely case for each option. Scenarios are informed by clinical judgement and knowledge of patient risk factors. These scenarios plus an accompanying graphic aid help patients formulate and express preferences and concerns about treatment burdens and outcomes. The clinician then provides a goal-concordant recommendation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Case/Worst Case (BC/WC) Geriatric Oncology (GeriOnc) communication tool
Description: The BC/WC framework guides clinicians to present a choice between two options and uses scenario planning (narrative descriptions of plausible outcomes that acknowledge uncertainty) to describe the best, worst, and most likely case for each option. Scenarios are informed by clinical judgement and knowledge of patient risk factors. These scenarios plus an accompanying graphic aid help patients formulate and express preferences and concerns about treatment burdens and outcomes. The clinician then provides a goal-concordant recommendation.
Study: NCT05824507

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Endometrial aspiration biopsies for CE diagnosis
Description: 1 ml of aspirate will be taken from the uterine cavity for histopathological examination and immunohistochemistry for CE during general anesthesia for scheduled surgery

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Endometrial aspiration biopsies for CE diagnosis
Description: 1 ml of aspirate will be taken from the uterine cavity for histopathological examination and immunohistochemistry for CE during general anesthesia for scheduled surgery
Study: NCT06466330

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: microparticles
Description: inert microparticles

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: embolization
Description: Injection of inert microparticles in neovessels using a microcatheter

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: sham embolization
Description: injection of saline solution
Study: NCT06301516

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: VR: The goal of the VR intervention is to provide youth an immersive, engaging, and therapeutic environment to reduce CD and CU traits

Intervention type: OTHER
Group type: OTHER
Intervention: Comparative Control
Description: Complete a one-time PowerPoint presentation that provides an overview of emotion expressions and instructions on how to recognize emotions in others.
Study: NCT06339463

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Distancing (EXSD)
Description: In the EXSD condition, participants will be instructed to describe exposure tasks from a self-distanced perspective (e.g., Emily is going to touch the spider).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Classic Exposure (EXC)
Description: In the classic condition (EXC), participants will be instructed to describe exposure tasks from a self-immersed perspective (I'm going to touch the spider).
Study: NCT05797766

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fluid Distribution Timetable
Description: a scheduled distribution of predetermined amounts of fluid intake daily depicted in a 5x6 table. The timetable has three major columns. The first column has six-time points of a day with a four-hour interval. The second column, which was divided into four sub-columns, reflects the percentage of fluid allotment for food, activities, medication, and thirst encounters. The percentage of fluid allocation was computed based on the patient's prescribed fluid restriction, usual time of food intake per day, usual level of activity, time of medication intake, and common time they encounter thirst for a day. The third column indicates the converted percentage of fluid allotment into milliliters.
Study: NCT04893668

Intervention type: OTHER
Intervention: Depression
Description: Any participants who develop depression symptoms according to DSM 5 criteria

Intervention type: OTHER
Intervention: Depression
Description: Any participants who develop depression symptoms according to DSM 5 criteria

Intervention type: OTHER
Intervention: Anxiety
Description: Any participants who develop anxiety symptoms according to DSM 5 criteria

Intervention type: OTHER
Intervention: Anxiety
Description: Any participants who develop anxiety symptoms according to DSM 5 criteria
Study: NCT04824261

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clotrimazol solution 1%
Description: 50 otomycosis randomized patients will receive Clotrimazol solution 1% The treatment will be locally applied for at least 2 weeks. All the patients will be followed up after the 1st week, 2nd week and after 1 month.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 4%boric acid in distilled water
Description: 50 otomycosis randomized patients will receive 4%boric acid in distilled water The treatment will be locally applied for at least 2 weeks. All the patients will be followed up after the 1st week, 2nd week and after 1 month.
Study: NCT06559124

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Traditional Physiotherapy + Sham Kinesiotape
Description: As exercise training, joint range of motion, flexion and abduction external cycle will be practiced with the gymnasts.~Circumference measurements will be taken for shoulder bone swelling and for atrophy.~Shoulder joint mobilizations will be applied (posterior cutting for flexion limitation, downward shifting and scapular mobilizations for abduction limitation).~Flexion and abduction will be stretched externally. Friction massage will be applied. Strengthening exercises for flexion, abduction and external rotation in the lower and upper segments of the shoulder with dumbbells and theraband, shoulder wheel and finger ladder will be practiced.~Codman exercises and staff exercises will be practiced.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotape with Facilitation Method + Traditional Physiotherapy
Description: Kinesio tape will be applied with 0 tension at the starting point when the arm is in a relaxed position and will be slightly heated. Since the deltoid muscle is a three-headed muscle, it will be applied with 0 tension in the flexed position at the elbow, for the front part, the arm with the elbow in full extension, and for the middle part of the deltoid, the I tape will be applied along the muscle without applying tension.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotape with Inhibition Method + Traditional Physiotherapy
Description: The Y-shaped kinesio tape will be placed on the deltoid muscle with inhibition and mechanical correction technique, and the Y-shaped kinesio tape will be placed on the supraspinatus muscle with inhibition technique, 3 cm below the humerus tuberculum deltoidea without tension. The Y tape will be applied along the outer edge of the anterior deltoid of the forearm with 15-25% light tension, and the posterior arm will be applied along the outer edge of the posterior deltoid with 15-25% light tension up to the lateral acromion. The last 3-5 cm of the tails will be applied to their permanent locations without tension. The shoulder will be held in maximum transverse extension and external rotation for the forearm of the Y support, and in 45 degrees transverse flexion and horizontal adduction for the posterior arm of the Y support. In addition, ultrasound, electrotherapy and cold application will be applied to the participants depending on their tolerance.
Study: NCT06493019

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Chemoradiation Pembrolizumab 200mg IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel 50 mg/m\^2 IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin AUC 2 IV

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation
Description: Delivered as per institutional standards

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Maintenance Pembrolizumab 400mg IV
Study: NCT06562283

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thumb test
Description: Thumb adduction test consisting of intermittent, repetitive isometric contractions lasting 5 seconds at incremental percentages of maximum force.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thumb test
Description: Thumb adduction test consisting of intermittent, repetitive isometric contractions lasting 5 seconds at incremental percentages of maximum force.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Grip test
Description: Muscle contraction gripping test, consisting of intermittent, repetitive isometric contractions lasting 5 seconds at incremental percentages of maximum force.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Grip test
Description: Muscle contraction gripping test, consisting of intermittent, repetitive isometric contractions lasting 5 seconds at incremental percentages of maximum force.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quadriceps Intermittent Fatigue test (QIF test))
Description: Quadriceps muscle contraction test consisting of intermittent, repetitive isometric contractions lasting 5 seconds at incremental percentages of maximum force.
Study: NCT05908097

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Avatar Intervention
Description: In the Virtual Reality Avatar Intervention experience, participants will see an avatar resembling themselves in a park setting. The Virtual Reality Empty Park experience is a habituation experience that does not contain avatars.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Virtual Reality Empty Park
Description: The Virtual Reality Empty Park experience is a habituation experience that does not contain avatars.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Empty Park
Description: The Virtual Reality Empty Park experience is a habituation experience that does not contain avatars.
Study: NCT05264363

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VIPUN Gastric Monitoring System prototype
Description: The Investigational Medical Device (IMD) is used simultaneously with the reference device (solid state high-resolution manometry) to record gastric intraluminal pressure for approximately 2.5 hours.
Study: NCT06482658

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transrectal perilesional/regional systematic biopsy (PB/RSB)
Description: The biopsy procedure was conducted by a highly skilled and experienced urologist who specializes in performing prostate biopsies. Prophylactic antibiotics were routinely used both before and one day prior to scheduled surgery. Each patient was placed in the left lateral position. The ultrasound equipment used included a color Doppler ultrasound diagnostic instrument (Hitachi HiVision, Philips Epiq 7), transrectal probes, and corresponding puncture needle guns. Color Doppler examination was performed from the base to the apex. For each predefined mpMRI suspicious lesion, urologists obtained nine cores at 5-mm intervals within and around the region of interest (penumbra) through transrectal prostate biopsy. The location of these nine cores depended on the shape and location of the suspicious lesion.
Study: NCT04080934

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Swimming
Description: Patients will participate in 8 weeks of the swimming program, which involves three weekly swimming sessions of 30 minutes minimum.
Study: NCT04281498

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Patients who are on ruxolitinib will continue their current dose. Patients who are not on ruxolitinib will receive ruxolitinib dosing based on platelet count

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enasidenib
Description: 50mg -100mg daily
Study: NCT06130202

Intervention type: DEVICE
Intervention: Echocardiographic findings
Description: Echocardiographic findings as Markers of Subclinical Cardiac dysfunction in Patients with Non-Alcoholic Fatty Liver Disease
Study: NCT06218550

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delta-9-THC
Description: Acute self-administration of inhaled or oral ∆9-THC by healthy adult research volunteers

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delta-9-THC
Description: Acute self-administration of inhaled or oral ∆9-THC by healthy adult research volunteers

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delta-8-THC
Description: Acute self-administration of inhaled or oral ∆8-THC by healthy adult research volunteers

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delta-8-THC
Description: Acute self-administration of inhaled or oral ∆8-THC by healthy adult research volunteers

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delta-8-THC
Description: Acute self-administration of inhaled or oral ∆8-THC by healthy adult research volunteers

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delta-8-THC
Description: Acute self-administration of inhaled or oral ∆8-THC by healthy adult research volunteers
Study: NCT05640648

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: User-Centered Implementation Strategy
Description: 1. 4 participant-facing components: 1a) TB education pamphlet helps index TB persons disclose the need for household screening to contacts. 1b) Contact identification algorithm helps CHWs and index TB persons accurately enumerate contacts. 1c) Sputum collection video instructs contacts to expectorate good-quality sputum. 1d) Community Health Riders transport CHWs, index persons with TB, and contacts by motorcycle taxi, and collect and transport sputum.~2. 3 community health-worker-facing components: a) Weekly CHW meetings create communities of practice (CoP), professionals organized for peer support and systematic learning. Meetings involve problem solving, review of audit and feedback reports, and didactics on TB care, among other activities. 2b) Audit and feedback reports on contact investigation performance indicators weekly (individual CHW) and monthly (health facility). 2c) A group-chat application facilitates peer support among CHWs.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Implementation Strategy
Description: Once an eligible TB patient agrees to participate, CHWs will visit the patient to assess the eligibility of close contacts to participate. For eligible contacts who agree to participate, the CHW will perform TB symptom screening and arrange subsequent microbiologic, clinical, and/or radiographic evaluation. Those screening TB symptom-positive will be asked to expectorate a sputum sample, unless under age 5. If under age 5 or unable to produce sputum, contacts will be referred to the health centre for evaluation. A CHW will transport sputum samples to the health-centre laboratory for microbiologic evaluation and later report the test results back to the contact. During the standard implementation strategy period, CHWs at all sites will receive the standard TB program training on TB contact investigation and supportive supervision from the on-site National TB Program focal person.
Study: NCT05841849

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aprepitant
Description: oral aprepitant capsules 125mg for D1 before chemotherapy, 80mg for D2 and D3

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Palonosetron
Description: oral palonosetron 0.5mg for D1 before chemotherapy; intravenous palonosetron 0.25mg for D1 before chemotherapy;

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palonosetron
Description: oral palonosetron 0.5mg for D1 before chemotherapy; intravenous palonosetron 0.25mg for D1 before chemotherapy;

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fosaprepitant
Description: intravenous fosaprepitant 150mg for D1 before chemotherapy
Study: NCT06482658

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combination of transrectal systematic biopsy and targeted biopsy
Description: The biopsy procedure was conducted by a highly skilled and experienced urologist who specializes in performing prostate biopsies. Prophylactic antibiotics were routinely used both before and one day prior to scheduled surgery. Each patient was placed in the left lateral position. The ultrasound equipment used included a color Doppler ultrasound diagnostic instrument (Hitachi HiVision, Philips Epiq 7), transrectal probes, and corresponding puncture needle guns. Color Doppler examination was performed from the base to the apex. Three to five transrectal targeted biopsies from the lesion were performed within and around the predefined mpMRI suspicious lesion, followed by fore-zone 12-core transrectal prostate biopsy.
Study: NCT04701086

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cationorm Pro
Description: Eye Drops

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vismed
Description: Eye Drops
Study: NCT06218550

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Consumption of a brownie or inhalation of ambient air through a cannabis vaporizer by health adult research volunteers
Study: NCT06058663

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Angiography
Description: Undergo mapping angiography

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Angiography
Description: Undergo mapping angiography

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy
Study: NCT06058663

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Yttrium-90 Microsphere Radioembolization
Description: Receive transarterial Y90 radioembolization

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Yttrium-90 Microsphere Radioembolization
Description: Receive transarterial Y90 radioembolization
Study: NCT05803343

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Regulating Together-Canine
Description: RT-C is an animal assisted, intensive outpatient group intervention for children with autism spectrum disorder and emotion dysregulation. RT-C meets for 1.5 hours, twice weekly for five weeks with concurrent youth and caregiver groups. The children progress through skills including relaxation training, arousal ratings, problem size, mindfulness, problem solving, and cognitive flexibility. The caregivers learn crisis management, reward systems, and coaching strategies for topics taught to the children. Homework is utilized to reinforce use of skills outside the group. The canines are present throughout as both a calming presence and teaching assistant. Children will be able to interact with the dog when practicing relaxation at the beginning of each session and throughout the session. Additionally, the dog will help to emphasize certain curriculum concepts.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Regulating Together-Standard
Description: RT-S an established, intensive outpatient group intervention for children with autism spectrum disorder and emotion dysregulation. It engages both caregivers and children and utilizes evidence-based intervention techniques including cognitive behavioral therapy (CBT), visuals, reinforcements, and scaffolding, and newer interventions such as mindfulness and acceptance-based therapy.
Study: NCT05161936

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lumasiran
Description: Lumasiran will be administered by SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lumasiran
Description: Lumasiran will be administered by SC injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered by SC injection.