TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04563195

Intervention type: DRUG
Group type: OTHER
Intervention: tibulizumab (LY3090106)
Description: subcutaneous injections of 300mg every 2 weeks over a period of 12 weeks
Study: NCT06132061

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: targeted prevention
Description: Therapeutic psychosocial interventions (including but not limited to cognitive behavioral therapy, acceptance commitment therapy, mindfulness training) to reduce patients' depressive symptoms.

Intervention type: OTHER
Group type: OTHER
Intervention: Waiting treatment.
Description: Waiting treatment.
Study: NCT05035732

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 18F-fluciclovine
Description: IV
Study: NCT04700540

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartwatch Reminder (SR) system
Description: The Smartwatch Reminder (SR) system will automatically transmit pictures and relevant information, such as name or relationship, to a smartwatch worn by the PWMC when family or friends visit.
Study: NCT04298437

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Addressing Depression and Positive Parenting Techniques (ADAPT) Program
Description: The intervention is a targeted parenting intervention that has modules that help parents build emotion regulation skills, distress tolerance skills and alternative and more helpful ways of thinking about the causes of their child's EBD. The program also includes behavioral parent training skills building modules.
Study: NCT05534958

Intervention type: DEVICE
Intervention: Accexible
Description: Speech Analysis

Intervention type: DEVICE
Intervention: Accexible
Description: Speech Analysis
Study: NCT05578209

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intermittent theta burst stimulation
Description: stimulatory protocol

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: intermittent theta burst stimulation
Description: stimulatory protocol
Study: NCT05593484

Intervention type: OTHER
Group type: OTHER
Intervention: Standard Referral
Description: Schools in the control condition will use standard referral, as determined by the school district. Standard referral is typically a letter home from the school to parents/caregivers of children who refer screening.

Intervention type: OTHER
Group type: OTHER
Intervention: Specialty Telemedicine Access for Referrals (STAR)
Description: The STAR intervention will include a lay-friendly smartphone or tablet that connects to tools necessary for an ear and hearing evaluation. If a child requires referral from hearing screening, a school nurse/teacher will complete the established protocol for the STAR intervention and send the information asynchronously to an audiologist for review.
Study: NCT05928520

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol 5%
Description: Topical tramadol 5%

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tramadol 5%
Description: Topical tramadol 5%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine 2%
Description: Topical Lidocaine 2%

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine 2%
Description: Topical Lidocaine 2%
Study: NCT04890288

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
Description: Demonstrate that airway management supported by oxygen supplementation (either HFNC or low flow oxygen) can prevent significant desaturation (SpO2 \> 85%) among patients in pediatric intensive care units (PICU) and neonatal intensive care units (NICU).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
Description: Demonstrate that airway management supported by oxygen supplementation (either HFNC or low flow oxygen) can prevent significant desaturation (SpO2 \> 85%) among patients in pediatric intensive care units (PICU) and neonatal intensive care units (NICU).
Study: NCT05698602

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NivolisMonitor
Description: NivolisMonitor comprises a sensing element and controller to measure respiratory values, such as pressure and flow optionnally temperature, relative humidity and oxygen concentration, of a patient being treated with a respiratory therapy devices NIV, CPAP or HDN.~NivolisMonitor is inserted between the respiratory assistance device and the mask or cannula inline with the standard patient circuit used routinely with the respiratory assistance device.~NivolisMonitor functions are:~* measure the respiratory values from the builtin sensor (Pressure, Flow, Temperature, Humidity, Oxygen fraction),~* store the measurements in the embedded memory~* extract from the measurement basic respiratory markers:~* detect if and when a patient is using the respiratory assist device,~* calculate leakage~* calculate respiratory frequency~* transmit the measured values via the NivolisBox component to NivolisPortal

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NivolisAnton
Description: NivolisAnton device enables wireless and remote communication from tcPCO2 monitors which measure transcuteanously CO2 and O2 partial pressures in the blood (tcPCO2 \& tcPO2) .~NivolisAnton device connects to the serial port of tcPCO2 monitor, detects if the monitor is actively measuring blood gas values, collects the measurements from the monitor by following manufacturer's communication protocol and stores the collected values in its internal memory. When applicable per the manufacturer recommendations, NivolisAnton collects the values to apply the drift correction as per the manufacturer recommendations.~NivolisAnton transmits the collected data to external receiving devices, such as Medical Devices (NivolisMonitor or another Medical Device that is granted approved data access by Vivardis) via Bluetooth or data servers (NivolisBox as an example) via WIFI. This data is thereafter transmitted by previously mentioned devices to the NivolisPortal server for archiving.
Study: NCT05516732

Intervention type: OTHER
Intervention: Positron Emission Tomography (PET) scan using CIMBI-36 tracer
Description: This scan creates images of regional serotonin release in by using a tracer compound called CIMBI to highlight the brains capacity to release serotonin.

Intervention type: OTHER
Intervention: Positron Emission Tomography (PET) scan using CIMBI-36 tracer
Description: This scan creates images of regional serotonin release in by using a tracer compound called CIMBI to highlight the brains capacity to release serotonin.

Intervention type: OTHER
Intervention: Magnetic Resonance Imaging (MRI) Scan
Description: MRI (magnetic resonance imaging) uses magnets alongside radio waves to create pictures of the brain

Intervention type: OTHER
Intervention: Magnetic Resonance Imaging (MRI) Scan
Description: MRI (magnetic resonance imaging) uses magnets alongside radio waves to create pictures of the brain

Intervention type: OTHER
Intervention: Positron Emission Tomography (PET) scan using DASB tracer
Description: To create images of the brain using a tracer called DASB, which is a highly selective for serotonin transporters, this highlights serotonin terminals and neurons in the brain.

Intervention type: OTHER
Intervention: Positron Emission Tomography (PET) scan using DASB tracer
Description: To create images of the brain using a tracer called DASB, which is a highly selective for serotonin transporters, this highlights serotonin terminals and neurons in the brain.

Intervention type: OTHER
Intervention: FP-CIT Single-photon Emission Computed Tomography (SPECT) scan
Description: A single-photon emission computerized tomography (SPECT) scan allows analysis of brain function by creating 3D Pictures using compounds called tracers.

Intervention type: OTHER
Intervention: FP-CIT Single-photon Emission Computed Tomography (SPECT) scan
Description: A single-photon emission computerized tomography (SPECT) scan allows analysis of brain function by creating 3D Pictures using compounds called tracers.

Intervention type: OTHER
Intervention: Lumbar puncture
Description: A lumbar puncture invovles a thin needle is inserted between the bones in your lower spine using local anaesthetic. This allows the collection of Cerebrospinal fluid ( CSF)

Intervention type: OTHER
Intervention: Lumbar puncture
Description: A lumbar puncture invovles a thin needle is inserted between the bones in your lower spine using local anaesthetic. This allows the collection of Cerebrospinal fluid ( CSF)
Study: NCT05888545

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: anti-adhesion diaphragm
Description: Participants will be asked to place an anti-adhesion diaphragm in the uterus for 3-7 days after the abortion procedure.
Study: NCT05466916

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise and diet education and instruction
Description: 1:1 or small group sessions consisting of educational materials and exercise instruction.
Study: NCT05478473

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chidamide combined with Toripalimab
Description: chidamide：oral, 30 mg/time, twice weekly; Toripalimab：intravenous drip, 240mg, once every 3 weeks
Study: NCT06216821

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard DAPT
Description: standard DAPT with aspirin and a P2Y12 inhibitor for 12 months after DES implantation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OPT-CAD score guided DAPT de-escalation
Description: De-escalation DAPT at 3 months for moderate to high risk patients and de-escalation DAPT at 1 month for low risk patients.
Study: NCT05536687

Intervention type: DEVICE
Group type: OTHER
Intervention: FeetMe
Description: Healthy volunteers will wear the insoles at 2 visits in hospitals (D0 and D8) and 2 visits at home (D1 and D7). The visits at the hospital will be composed of 3 tests of 6 min. in various conditions in a hospital environment :~* In degraded conditions, i.e. a 10m corridor, evaluated simultaneously by the FeetMe® system and an evaluator~* In degraded condition, a 10m corridor, evaluated simultaneously by the FeetMe® system and an odometer and evaluator~* Under the conditions recommended for the 6-minute test (ref), i.e. a 30m corridor, evaluated simultaneously by the FeetMe® system and the evaluator A rest time of 15 min minimum will be respected between each test. The visits at home will be composed of a 6-minute test at home or outdoors (quiet place, flat, hard surface, few or no passages, ideally no obstacles, covered if weather conditions are not suitable) with a 10-meter track that you can define simply with equipment provided by the promoter.
Study: NCT06141863

Intervention type: OTHER
Intervention: questionnaire
Description: Neck Disability Index, The Fonseca Anamnestic Index (FAI) and Visual Analogue Scale (VAS)

Intervention type: OTHER
Intervention: questionnaire
Description: Neck Disability Index, The Fonseca Anamnestic Index (FAI) and Visual Analogue Scale (VAS)
Study: NCT05129540

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Custom-made foot orthosis
Description: The foot orthoses for group A will be custom made using phenolic foam molds of the feet. They consist of a polypropylene layer of 3 mm from heel to just proximal to the metatarsal heads, and an upper sheet of 30 Shore A polyethylene foam.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo orthosis
Description: A flat insole made of the same material as the upper layer of the custom-made foot orthoses used for group custom-made foot orthosis.
Study: NCT06397573

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Reirradiation
Description: Ablative reirradiation of 50 Gy in 5 fractions (5 sessions) that will occur once per day, either for 5 days in a row, or every other day.
Study: NCT06196346

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychotherapy
Description: see group description
Study: NCT05490030

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNO155
Description: Single oral dose of TNO155 on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNO155
Description: Single oral dose of TNO155 on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNO155
Description: Single oral dose of TNO155 on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNO155
Description: Single oral dose of TNO155 on Day 1
Study: NCT04749862

Intervention type: OTHER
Intervention: Online symptom reporting
Description: Online symptom reporting questionnaire with linked self-management advice

Intervention type: OTHER
Intervention: Online symptom reporting
Description: Online symptom reporting questionnaire with linked self-management advice
Study: NCT06123598

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Therapeutic exercise program plus action observation training
Description: Participants make an observation of actions related to the training they are going to perform before each session. Subsequently, they perform the therapeutic exercise program of 6 sessions in a period of 2 weeks.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Therapeutic exercise program plus sham action observation training
Description: Participants make a sham observation before each session. Subsequently, they perform the therapeutic exercise program of 6 sessions in a period of 2 weeks.
Study: NCT06069414

Intervention type: OTHER
Intervention: Type of anesthesia induction
Description: Patients will receive inhalatory or intravenous anesthesia at their choice; both groups will be evaluated with lung ultrasound after induction to detect ultrasonografic signs of atelectasis

Intervention type: OTHER
Intervention: Type of anesthesia induction
Description: Patients will receive inhalatory or intravenous anesthesia at their choice; both groups will be evaluated with lung ultrasound after induction to detect ultrasonografic signs of atelectasis
Study: NCT05742880

Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Blood gas analysis
Description: Blood gas analyisis

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Wearing a Surgical Facemask
Description: Wearing a Surgical Facemask

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Wearing a FFP2- Facemask
Description: Wearing a FFP2- Facemask

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Wearing no Mask
Description: Wearing no Mask
Study: NCT06552650

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Four supervised exercise interventions after surgery: One exercise education session per week from postoperative day 5 through 1 month Subsequent home-based exercise: Home-based exercise recommendations from 1 month to 3 months post-surgery

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: The full spectrum of patient care practices in which clinicians have the opportunity (which is not necessarily seized) to individualize care
Study: NCT06553495

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nerve block
Description: Analgesic effect of different nerve blocks

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Nerve block
Description: Analgesic effect of different nerve blocks
Study: NCT04886778

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low-carbohydrate diet
Description: Participants will be instructed to maintain a daily dietary energy intake of less than 1600 kcal.Based on the low-carbohydrate diet model, the proportion of daily intake of carbohydrate was about 30%, and this ratio was up to 30%, 40% of protein and fat respectively.Participants should choose unprocessed whole grains, potatoes, vegetables, meat, fish, eggs, soy products, sugar-free dairy products, designated varieties of low-GI fruits and nuts, etc. as breakfast, and avoid processed meats and high-fat red meat and poultry skins. Standard nutritious meal instead of daily lunch and dinner meals, that is to say, participants should take one nutritional bar for lunch and dinner (310 kcal totally, provided by Guangzhou Nanda Fett Nutrition and Health Consulting Co., Ltd.), and avoid starchy foods. Other food varieties are required to be the same as breakfast. Plant oil is the main cooking oil, and participants will be instructed to drink 2L water every day.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Low-carbohydrate diet
Description: Participants will be instructed to maintain a daily dietary energy intake of less than 1600 kcal.Based on the low-carbohydrate diet model, the proportion of daily intake of carbohydrate was about 30%, and this ratio was up to 30%, 40% of protein and fat respectively.Participants should choose unprocessed whole grains, potatoes, vegetables, meat, fish, eggs, soy products, sugar-free dairy products, designated varieties of low-GI fruits and nuts, etc. as breakfast, and avoid processed meats and high-fat red meat and poultry skins. Standard nutritious meal instead of daily lunch and dinner meals, that is to say, participants should take one nutritional bar for lunch and dinner (310 kcal totally, provided by Guangzhou Nanda Fett Nutrition and Health Consulting Co., Ltd.), and avoid starchy foods. Other food varieties are required to be the same as breakfast. Plant oil is the main cooking oil, and participants will be instructed to drink 2L water every day.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic compound preparations
Description: The probiotic compound preparation，named Junyi Yili® Probiotics，is made of Lactobacillus reuteri, Lactobacillus gasseri, Lactobacillus acidophilus and Bifidobacterium lactis, and resistant dextrin contained water-soluble dietary fiber. The subjects will take this probiotic compound preparations with purified water after three meals every day, 1 sachet each time.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is made of resistant dextrin which contained water-soluble dietary fiber. The subjects were taken this placebo with purified water after three meals every day, 1 sachet each time.
Study: NCT05661604

Intervention type: OTHER
Intervention: No Intervention
Description: This is an observational study to assess the incidence and key disease characteristics of symptomatic acute respiratory viral infections in a high-risk population at risk for poor outcomes. Duration of each participant will be up to 12 months.
Study: NCT03553524

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: morning HIIT --> afternoon HIIT
Description: Arm 1 will start with morning HIIT at visit 2 and afternoon HIIT at visit 3

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: afternoon HIIT --> morning HIIT
Description: Arm 2 will start with afternoon HIIT at visit 2 and morning HIIT at visit 3
Study: NCT06404138

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Geriatric Activation Program (GAPP) Home version
Description: The rehabilitation at home intervention consists of three 45 minutes session per week (total of 18 sessions) with a different focus for each session. The therapy is goal-oriented and includes functional exercises in the home where possible (e.g. transfers such as getting out of bed, walking to the toilet etc.). There are three sessions per week: 1 for training strength, 1 for training balance and 1 for speed, coordination and endurance. Each session will start with gait rehabilitation as a warming-up.~For each session, a set of exercises with varying levels of difficulty is available. As rehabilitation needs are diverse, the therapist is expected to choose the most appropriate exercise and the difficulty level of the exercise for the individual older person. This also includes scaling the exercises to the individual progression of the older person.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care
Description: Standard of care, without any restrictions.
Study: NCT05500963

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical nerve stimulation
Description: Electrical stimulation applied over selected leg muscle will activate sensory receptors that will transmit signals back into the central nervous system.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous electrical nerve stimulation
Description: Electrical stimulation applied over selected leg muscle will activate sensory receptors that will transmit signals back into the central nervous system.
Study: NCT05427240

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pre-Test Intervention
Description: Secure and accessible by private code only, the web-based intervention will provide users with a the results of their clinical genetic testing results and a detailed summary of what those results mean. Additionally, an individualized summary will also be included.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pre-Test Intervention
Description: Secure and accessible by private code only, the web-based intervention will provide users with a the results of their clinical genetic testing results and a detailed summary of what those results mean. Additionally, an individualized summary will also be included.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Standard of Care with a Genetic Counselor by Remote Services

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Standard of Care with a Genetic Counselor by Remote Services

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Standard of Care with a Genetic Counselor by Remote Services

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post-Test Intervention
Description: Secure and accessible by private code only, the web-based intervention will provide users with a the results of their clinical genetic testing results and a detailed summary of what those results mean. Additionally, an individualized summary will also be included.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post-Test Intervention
Description: Secure and accessible by private code only, the web-based intervention will provide users with a the results of their clinical genetic testing results and a detailed summary of what those results mean. Additionally, an individualized summary will also be included.
Study: NCT04655573

Intervention type: PROCEDURE
Intervention: Breast Cancer Tumor Resection
Description: Patients with ABC will be receiving a biopsy, and a PDMO from the patient's biopsies will be generated from it. It is a model correlating clinical response with PDMO sensitivity to the most common forms of chemotherapy used in advanced breast cancer care.
Study: NCT06078059

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Knee aspiration + UCB-MSCs
Description: Knee aspiration and the application of cultered allogeneic umbilical cord blood-derived mesenchymal stromal stem cells (UCB-MSCs).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Knee aspiration
Description: Knee aspiration