TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06317051

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin 10mg Tab
Description: Dapagliflozin will be administered as a comparator to the placebo to assess its effects on weight reduction

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin 10mg Tab
Description: Dapagliflozin will be administered as a comparator to the placebo to assess its effects on weight reduction

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pitavastatin 4 Mg Oral Tablet
Description: Pitavastatin tablets will be administered as a comparator to Rosuvastatin/Ezetimibe 10mg/10mg tablets to assess and compare their effects on LDL concentrations

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Pitavastatin 4 Mg Oral Tablet
Description: Pitavastatin tablets will be administered as a comparator to Rosuvastatin/Ezetimibe 10mg/10mg tablets to assess and compare their effects on LDL concentrations

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rosuvastatin and Ezetimibe
Description: Rosuvastatin/Ezetimibe 10mg/10mg tablets will be administered as a comparator to pitavastatin to assess and compare their effects on LDL concentrations

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rosuvastatin and Ezetimibe
Description: Rosuvastatin/Ezetimibe 10mg/10mg tablets will be administered as a comparator to pitavastatin to assess and compare their effects on LDL concentrations

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo tablets are visually identical to the active drug tablets and will be administered as a comparator to Dapagliflozin.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo tablets are visually identical to the active drug tablets and will be administered as a comparator to Dapagliflozin.
Study: NCT04665141

Intervention type: BIOLOGICAL
Intervention: Mepolizumab
Description: Mepolizumab will be prescribed freely by the treating physician according to real-life conditions.

Intervention type: BIOLOGICAL
Intervention: Omalizumab
Description: Omalizumab will be prescribed freely by the treating physician according to real-life conditions.

Intervention type: BIOLOGICAL
Intervention: Reslizumab
Description: Reslizumab will be prescribed freely by the treating physician according to real-life conditions.

Intervention type: BIOLOGICAL
Intervention: Benralizumab
Description: Benralizumab will be prescribed freely by the treating physician according to real-life conditions.

Intervention type: BIOLOGICAL
Intervention: Dupilumab
Description: Dupilumab will be prescribed freely by the treating physician according to real-life conditions.
Study: NCT05955716

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality glasses
Description: Virtual reality glasses are a device suitable for every mobile phone. It is used to watch the 360 degree video selected from the Youtube program.
Study: NCT06225128

Intervention type: OTHER
Intervention: Biobanking blood
Description: Additional volume of 30mL (EDTA) At Screening, pre-Cycle 1 Day 1,Day 1 H8, Day 2, Day of post-cycle 1 and post-cycle 6 evaluation.

Intervention type: OTHER
Intervention: Bone marrow specimens
Description: Additional volume of 2mL (EDTA)~* at screening for correlative studies,at Day 7 for smears and for correlative studies.~* Post-cycle 1 and post-cycle 6 evaluations for correlative studies.~Optionnal :~Trephine biopsy at screening and at post-cycle 1 and 6 evaluations (performed at the same time as aspiration)
Study: NCT06134180

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CONFIDENCE-AI
Description: Multicomponent psychoeducational intervention focused on financial wellbeing
Study: NCT06069193

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Touch Intervention
Description: The participants will be examined, with various areas in the neck and upper back being palpated. Subsequently, the exercises to be performed at home will be demonstrated by the experimenter. The experimenter will ensure correct execution by touching specific areas in the neck and upper back of the participants. Finally, the participants will be provided with a cream to be applied to the affected regions.~Placebo cream:~The participants receive an inert placebo cream, which is a standard basic cream infused with lemon oil, produced by a local pharmacy. Participants are informed that they are about to receive an effective analgesic cream.~Placebo exercises:~Participants are assigned a series of five core exercises, with an optional supplementary exercise available in case any of the core exercises proves ineffective for the participants. Participants are led to believe that these exercises are expected to have therapeutic effects.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Control
Description: The participants will be examined, and they will be asked to describe as accurately as possible the regions where they experience pain. Subsequently, the experimenter will demonstrate the exercises to be performed at home. Finally, the participants will be provided with a cream to be applied to the affected regions.~Placebo cream:~The participants receive an inert placebo cream, which is a standard basic cream infused with lemon oil, produced by a local pharmacy. Participants are informed that they are about to receive an effective analgesic cream.~Placebo exercises:~Participants are assigned a series of five core exercises, with an optional supplementary exercise available in case any of the core exercises proves ineffective for the participants. Participants are led to believe that these exercises are expected to have therapeutic effects.
Study: NCT05943691

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hetrombopag 5mg po qd
Description: hetrombopag 5mg po qd for 8 weeks, combining with dexamethasone 40 mg qd for 4 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High-dose Dexamethasone
Description: dexamethasone 40 mg qd for 4 days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: High-dose Dexamethasone
Description: dexamethasone 40 mg qd for 4 days
Study: NCT06527560

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cefuroxime
Description: Intravenous cefuroxime 750 mg every 8 hours

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cefuroxime Axetil
Description: Oral cefuroxime 500 mg every 12 hours
Study: NCT05733286

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Suvorexant 20 mg
Description: Administer Suvorexant versus placebo every evening for Post-Operative Day (POD) 0,1, \&2

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administer Suvorexant versus placebo every evening for Post-Operative Day (POD) 0,1, \&2
Study: NCT05847517

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metoprolol Injection
Description: A dilution of 15 mg Metoprolol tartrate in 100 ml saline shall be performed and infused for 10 minutes. No dose reduction or increase is allowed. Systolic blood pressure and heart rate shall be measured 3 and 6 minutes after starting the infusion.~In case of a consistent drop in systolic blood pressure or heart rate, the infusion shall be stopped and the infusion noted.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: saline 0.9%
Description: A dilution of 0.9% sodium chloride in 100 ml saline shall be performed and infused for 10 minutes. No dose reduction or increase is allowed. Systolic blood pressure and heart rate shall be measured 3 and 6 minutes after starting the infusion.~In case of a consistent drop in systolic blood pressure below 110 mmHg or heart rate below 60 bpm, the infusion shall be stopped and the infusion noted.
Study: NCT06553703

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acceptance and commitment therapy based group psychoeducation
Description: Acceptance and commitment therapy-based group psychoeducation aimed at increasing nursing students' psychological flexibility and reducing their somatic symptoms.
Study: NCT06559267

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Remaking Recess
Description: Remaking Recess (RR) is a school-based social engagement intervention designed to enhance elementary school contextual factors to better support peer engagement during recess. Remaking Recess is delivered to educators through direct training and in vivo coaching by a certified Remaking Recess Coach.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remaking Recess
Description: Remaking Recess (RR) is a school-based social engagement intervention designed to enhance elementary school contextual factors to better support peer engagement during recess. Remaking Recess is delivered to educators through direct training and in vivo coaching by a certified Remaking Recess Coach.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEAM
Description: Schools that are randomized to the TEAM condition will receive an additional implementation support intervention. TEAM will leverage existing human resources in the school to specifically focus on developing an implementation blueprint to foster a supportive implementation context for paraeducators to use Remaking Recess.
Study: NCT05920590

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF
Description: The protocol will be individualized and will last 45 minutes. The following techniques will be applied:~* Application of the hold - relax technique to increase the range of motion of knee flexion.~* Rhythmic initiation with the application of diagonal trunk and lower limb shapes.~* Application of stabilizing reversals from a sitting and standing position.~* Application of dynamic reversals from a standing position.~* Rhythmic stabilization.~* Combination of isotonics.~* Gait retraining.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF plus Tendon Vibration
Description: Participants in this group will be given the same exercise program as Group 1 combined with the application of tendon vibration. Tendon vibration will be applied on both quadriceps' tendons in three weekly sessions (not on the same day as the exercise program). To implement the protocol, 100 Hz frequency mechanical stimulation will be applied.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants in this group will be given an exercise leaflet for home-based exercises and will be instructed to perform these exercises three times a week for the same period as the other two groups (6 weeks). They will also be given recommendations to maintain and increase their physical activity.
Study: NCT06218316

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: botulinum toxin A
Description: Botulinum Neurotoxin A (BoNT-A) Injections will administered directly into the bulk of the muscles, with two injection sites at each head of the gastrocnemius and two sites into the medial hamstring. one vial of BoNT-A in 2 mL of 0.9% sodium chloride solution. followed by a 3-month rehabilitation program. The entire intervention including rTMS, BoNT-A, and rehabilitation training program spanned a period of three months.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: botulinum toxin A
Description: Botulinum Neurotoxin A (BoNT-A) Injections will administered directly into the bulk of the muscles, with two injection sites at each head of the gastrocnemius and two sites into the medial hamstring. one vial of BoNT-A in 2 mL of 0.9% sodium chloride solution. followed by a 3-month rehabilitation program. The entire intervention including rTMS, BoNT-A, and rehabilitation training program spanned a period of three months.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Magnetic Stimulation
Description: Repeated Transcranial Magnetic Stimulation (rTMS) Stimulation coil will strategically place on the primary motor cortex (M1), The patients received 1500 pulses per session, two sessions per week for 3 months, in a combination with 3-month rehabilitation program.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Magnetic Stimulation
Description: Repeated Transcranial Magnetic Stimulation (rTMS) Stimulation coil will strategically place on the primary motor cortex (M1), The patients received 1500 pulses per session, two sessions per week for 3 months, in a combination with 3-month rehabilitation program.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation Training Protocol
Description: Rehabilitation Training Protocol: As part of the study protocol, all participating children underwent a comprehensive weekly routine rehabilitation training program. Training Schedule: sessions will conduct for duration of 45 minutes. Training occurred four days a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation Training Protocol
Description: Rehabilitation Training Protocol: As part of the study protocol, all participating children underwent a comprehensive weekly routine rehabilitation training program. Training Schedule: sessions will conduct for duration of 45 minutes. Training occurred four days a week.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation Training Protocol
Description: Rehabilitation Training Protocol: As part of the study protocol, all participating children underwent a comprehensive weekly routine rehabilitation training program. Training Schedule: sessions will conduct for duration of 45 minutes. Training occurred four days a week.
Study: NCT05783141

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: New prebiotic follow-on formula, randomly assigned to healthy toddlers
Description: Standard follow-on formula administered orally

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Standard follow-on formula, randomly assigned to healthy toddlers
Description: Standard follow-on formula administered orally
Study: NCT05264779

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Periviable GOALS DST
Description: An iPad application that contains outcomes information, values clarification and embedded short documentary style videos. The tool was designed with low-literacy and low-numeracy populations in mind, and utilizes graphics and video content to enhance meaning-making of complex medical information and jargon. The GOALS DST refers patients back to their physicians to discuss specific treatment options, local outcomes, and management strategies available to them. The DST's content focuses largely on helping patients better understand the choice they have between comfort care and life-sustaining efforts in the context of periviable delivery.
Study: NCT06253442

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Patients will receive Supra scapular nerve block and Axillary nerve block.
Description: Suprascapular nerve block will be done by posterior approach with the patient sitting up and leaning forward. The linear ultrasound probe will identify the suprascapular nerve, after that we will inject aliquots of Sunnypivacaine 0.5% 15 ml after negative aspiration of blood.~For the axillary nerve block, the ultrasound transducer will be placed in a sagittal plane over the humeral head on the posterior aspect of the arm to identify the deltoid muscle, neck of the humerus, the teres minor muscle, the circumflex humeral artery, and the triceps muscle. After the neurovascular quadrangular space identification and observing the deltoid muscle response to stimulation, a local anesthetic (10 ml 0.25% Sunnypivacaine) will be injected with the in-plain technique.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Patients will receive Interscalene block.
Description: Interscalene nerve block will be done ultrasound-guided using a linear array ultrasound transducer. While the patient is in the supine position, the head will be rotated to the contralateral side of the block. Ultrasound scanning will be performed in the transverse plane with long axis of the probe parallel to clavicle to visualize the brachial plexus between the anterior and middle scalene muscles. A 5-cm 22-gauge insulated needle will then be inserted in line with the probe in a lateral-to-medial needle orientation. Local anesthetic solution will then be injected in 15-ml aliquots Sunnypivacaine 0.5% after negative aspiration for blood to achieve spread posterior to or between the C5 and C6 nerve roots.
Study: NCT04430452

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Given IV

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiation Therapy
Description: Undergo hypofractionated RT
Study: NCT05780320

Intervention type: OTHER
Intervention: Prophylactic amiodarone and posterior pericardiotomy
Description: Patients after the implementation of the protocol receive postoperative prophylactic amiodarone and a posterior pericardiotomy.~The amiodarone regimen consists of amiodarone 1mg/min x 10 hours (600 mg total) via central line upon arrival to the intensive care unit followed by 400 mg PO BID on postoperative days 1 and 2 followed by 200 mg PO BID on postoperative days 3 and 4 or until discharge, whichever occurs first.~The posterior pericardiotomy occurs during the cardiac procedure.
Study: NCT04430452

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiation Therapy
Description: Undergo hypofractionated RT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Given IV
Study: NCT04730258

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CFI-400945
Description: The starting dose is 32 mg/day for escalation arms and the recommended starting dose for the expansion arms.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CFI-400945
Description: The starting dose is 32 mg/day for escalation arms and the recommended starting dose for the expansion arms.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Azacitidine will be given at its labeled dose and schedule
Study: NCT05373537

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral therapy for Insomnia
Description: Caregiver with insomnia will receive CBT-Insomnia and will be trained to implement CBT-I tailored for their child with Autism Spectrum Disorder and Insomnia

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral therapy for Insomnia
Description: Caregiver with insomnia will receive CBT-Insomnia and will be trained to implement CBT-I tailored for their child with Autism Spectrum Disorder and Insomnia
Study: NCT03980769

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thiotepa
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine Phosphate
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rabbit Anti-Thymocyte Globulin
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Allogeneic Hematopoietic Stem Cell Transplantation
Description: Undergo HCT via infusion

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study: NCT06510439

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Need to Be Needed Intervention
Description: Interventionist-supported volunteering intervention that targets opportunities creating social connections that matter through focus on kindness and gratitude throughout the intervention.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Control Group
Description: Weekly non-directive listening support
Study: NCT04700098

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-based behavioral treatment for insomnia
Description: Internet version of cognitive-behavioral treatment for insomnia

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online insomnia patient education
Description: Online insomnia patient education
Study: NCT06535880

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electric Current Stimulation
Description: Electric stimulation with a Digitimer DS7AH HV Current Stimulator delivered with 4 shielded electrodes mounted on the participants head and arm
Study: NCT04544917

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SmartManage for HIV+ cancer survivors
Description: Ten weekly therapist delivered group sessions delivered via web conference. Sessions focus on cognitive behavioral stress management, psychoeducation, and management strategies for dual diagnosis of HIV and cancer. Participants will have access to the SmartManage web platform which has all intervention material, resources, and exercises.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational Control
Description: Participants in the control condition will view ten videos over ten weeks, consisting of informational and educational material relevant to cancer and HIV.