TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04906005

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gadopiclenol
Description: administration by intravenous (IV) bolus injection at 2 mL/s rate without dilution, followed by a saline flush of at least 5 mL at the same rate to ensure complete injection of the contrast agent.The gadopiclenol administration is performed by power injecto

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: intravenous (IV) bolus injection at 2 mL/s, followed by a saline flush of at least 5 mL to be in the same conditions as for gadopiclenol administration.The gadopiclenol administration is performed by power injector
Study: NCT05073770

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Titan Condom
Description: The test condoms have the following specifications throughout the study:~1. The plain 64mm condom (i.e., N64): Length 223 ±5mm, width 64±1mm, thickness (single wall) 0.070± 0.005mm, and beading thickness 1.25±0.05mm.~2. The plain 69mm condom (i.e., N69): Length 223 ±5mm, Width 69±1mm, Thickness (single wall) 0.070± 0.005mm, Beading thickness 1.25±0.05mm.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Titan Condom
Description: The test condoms have the following specifications throughout the study:~1. The plain 64mm condom (i.e., N64): Length 223 ±5mm, width 64±1mm, thickness (single wall) 0.070± 0.005mm, and beading thickness 1.25±0.05mm.~2. The plain 69mm condom (i.e., N69): Length 223 ±5mm, Width 69±1mm, Thickness (single wall) 0.070± 0.005mm, Beading thickness 1.25±0.05mm.
Study: NCT05099601

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Silymarin
Description: The patients will use topical silymarin 0.7% cream on the face twice daily(home use).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microneedling
Description: Patients will be subjected to microneedling sessions on one side of the face. Three consecutive sessions, 4 weeks apart (0, 4, 8 weeks), will be performed by dermapen. Sessions will be done by well trained physician.
Study: NCT05677789

Intervention type: DIAGNOSTIC_TEST
Intervention: Medical observation
Description: Likely suitable for home treatment

Intervention type: DIAGNOSTIC_TEST
Intervention: Supportive treatment (BSC)
Description: Consider hospital supervised treatment

Intervention type: DIAGNOSTIC_TEST
Intervention: Intensive care management
Description: Manage in hospital as severe pneumonia
Study: NCT05389800

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Upper Extremity Aerobic Exercise
Description: Using a cycle-ergometer (Monark 881E)
Study: NCT05166889

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered subcutaneously, equivalent volume to tozorakimab through week 52.
Study: NCT06391801

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neuroathletic training
Description: Specific Neuroathletic training exercises were performed to improve balance ability of post stroke patients

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional movement therapy in outpatient rehabilitation
Description: Traditional movement therapy in outpatient rehabilitation
Study: NCT04779931

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Convoy-Pal
Description: 12 week mobile self-management intervention with palliative care resources.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Convoy-Pal
Description: 12 week mobile self-management intervention with palliative care resources.
Study: NCT06156124

Intervention type: DIAGNOSTIC_TEST
Intervention: Psychological tests and psychosocial questionnaires
Description: Assessment of psychological functioning of adolescents (including occurrence of internalizing and externalizing problems, coping with adolescent crisis), family functioning (siblings relations, parental attitudes, parentification), functioning at school (school achievement, extracurricular activities), relations with peers (time spending with peers, number of friends, quality of relations). Further, the sociodemographic variables will be also measured.

Intervention type: DIAGNOSTIC_TEST
Intervention: Psychological tests and psychosocial questionnaires
Description: Assessment of psychological functioning of adolescents (including occurrence of internalizing and externalizing problems, coping with adolescent crisis), family functioning (siblings relations, parental attitudes, parentification), functioning at school (school achievement, extracurricular activities), relations with peers (time spending with peers, number of friends, quality of relations). Further, the sociodemographic variables will be also measured.

Intervention type: DIAGNOSTIC_TEST
Intervention: Psychological tests and psychosocial questionnaires
Description: Assessment of psychological functioning of adolescents (including occurrence of internalizing and externalizing problems, coping with adolescent crisis), family functioning (siblings relations, parental attitudes, parentification), functioning at school (school achievement, extracurricular activities), relations with peers (time spending with peers, number of friends, quality of relations). Further, the sociodemographic variables will be also measured.

Intervention type: DIAGNOSTIC_TEST
Intervention: Psychological tests and psychosocial questionnaires
Description: Assessment of psychological functioning of adolescents (including occurrence of internalizing and externalizing problems, coping with adolescent crisis), family functioning (siblings relations, parental attitudes, parentification), functioning at school (school achievement, extracurricular activities), relations with peers (time spending with peers, number of friends, quality of relations). Further, the sociodemographic variables will be also measured.
Study: NCT05366205

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oral nutritional supplement
Description: Enteral nutritional emulsion(TPF-T) will be given by oral intake,400ml per day, lasting for 7-10 days.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Nutrition consultation
Description: Nutritional treatment advice will be given
Study: NCT05404984

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry cupping with core stabilization exercises
Description: 12 patients will receive dry cupping technique for 10 minutes followed by 10 repetitions of each core stabilization exercise in different positions. All the patients will receive this treatment once a week for 6 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Core stabilization exercises
Description: A total of 12 patients will perform 10 repetitions of each core stabilization exercise in different positions. All the patients will receive this treatment once a week for 6 weeks.
Study: NCT05983900

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: BRIX3000
Description: chemo-mechanical caries removal agent

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: papacarie
Description: chemo-mechanical caries removal agent

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: hand excavation
Description: mechanical caries removal
Study: NCT05754775

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Calorie restriction via total food replacement
Description: Restricted foods designed by a clinical nutritionist that delivers to home for diabetic patients.
Study: NCT05873140

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: application LINE
Description: Online lifestyle modification education for weight loss
Study: NCT05955859

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Samplings from patient's affected paranasal sinus
Description: Samplings from patient's affected paranasal sinus during endoscopic surgery.
Study: NCT05885256

Intervention type: DIAGNOSTIC_TEST
Intervention: Amending current standard trauma order set
Description: Blood draw happens as part of routine clinical care for all trauma activations. As part of the study, we will use existing blood that is drawn as part of routine clinical care, or when necessary, draw additional blood to obtain samples at 0, 3, 6, 12, 18, and 24 hours assessing ionized calcium, serum calcium, and magnesium. We will strive to have draws occur within +/- 1 hour of the goal times. However, given that the blood draws will be performed by way of the clinical team and the unpredictable nature of trauma care, missed draws or draws out of the goal time frame will not be considered protocol violations
Study: NCT05107401

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults
Description: Adolescents and young adults will participate in a crowdsourcing contest to create digital materials to reduce HIV stigma in order to increase HIV testing. Entries will be judged by a community judging panel and expert judging panel. Winning entries will be selected for the digital intervention and presented to participants in the intervention arm.
Study: NCT06082128

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: FOCUSau
Description: FOCUSau is a self-administered web-based intervention and completed autonomously via the internet by the dyad. Delivery encompasses the completion of four prescribed consecutive FOCUSau sessions (with three weeks between each session) over a period of 12 weeks.~The sessions are completed simultaneously by the patient and family carer, together at a computer. The intervention sessions can be completed at any time within the 12-week timeframe. Participants receive tailored individual and dyadic messages according to the information provided at study enrollment and their responses to questions within the sessions. Dyads are also provided with an online personal workbook containing the results of interactive exercises completed during the internet sessions. Any information sheets that the dyad indicated as 'of interest to them' during the internet sessions are included as a hyperlink in their personal workbook which also contains evidence-based local advanced cancer related resources.
Study: NCT05582837

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nortriptyline + topiramate
Description: nortriptyline (7.5mg) + topiramate (10mg) taken 1x per day and escalate weekly as needed for 8 weeks
Study: NCT06480643

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High load exercise type
Description: Heavier load, fewer reps

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low load exercise type
Description: Lighter load, more reps
Study: NCT05582837

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nortriptyline + topiramate
Description: nortriptyline (7.5mg) + topiramate (10mg) taken 1x per day and escalate weekly as needed for 8 weeks
Study: NCT05777525

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: application of cream La Chinata
Description: application of cream enriched with essential oil
Study: NCT05723614

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TRUE HAVEN
Description: The two components of the TRUE HAVEN intervention are: housing support for recently incarcerated people as well as family members of currently incarcerated people, and mental wellness training for neighborhood residents to participate in trauma-informed care training sessions.
Study: NCT05508971

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: DISE-Directed Surgery
Description: Participants randomized to DISE-directed surgery will undergo one or more potential procedures in a single surgery (i.e. DISE and subsequent sleep surgery performed) concurrently under the same general anesthetic), depending on anatomic assessment.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Adenotonsillectomy
Description: Tonsil and adenoid removal
Study: NCT06117995

Intervention type: OTHER
Intervention: Assessment the pre-washed sperm motility before IUI
Description: The pre-washed sperm motility will be assessed by using WHO 2021 guidelines, stratified into four groups.
Study: NCT05942404

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mechanical bowel preparation
Description: mechanical bowel preparation before surgery
Study: NCT06572930

Intervention type: DRUG
Intervention: Gonal-f (gonadotropin)
Description: Women will be given 300 IU Gonal-F daily from cycle day 2 or 3. Gonal F will be injected at 8 pm daily. They will all receive cetrorelix acetate 250 mcg/day (Cetrotide) subcutaneously from stimulation day 5 onwards until and including the trigger day. Cetrotide will be administered at 08:00 am.
Study: NCT05864716

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Colonscopic probiotics spray
Description: 20g of multi-strain probiotics powder via colonoscopic spray. The probiotic used in this study is SynPro-15G, which has 15 probiotics, including Bacillus coagulans BC1031, Bifidobacterium bifidum BB14, Bifidobacterium breve BR18, Bifidobacterium animalis subsp. lactis BAL06, Bifidobacterium longum (B. longum) BL986, Lactobacillus acidophilus LA1063, Lactobacillus casei LC122, Lactobacillus delbrueckii subsp. lactis LDL114, Lactobacillus fermentum LF26, Lactobacillus helveticus LH43, Lactobacillus paracasei LPC12, Lactobacillus plantarum LP198, Lactobacillus reuteri LR21, Lactobacillus rhamnosus LRH10, and Streptococcus thermophilus ST37 at a concentration of 2x1010 CFU/g (Synbiotech Corp., Kaohsiung, Taiwan). SynPro-15G is made either as a vial of powder (2x1011 CFU /vial) for colonoscopic spray or as a capsule (2x1010 CFU/capsule) for oral intake.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Colonscopic probiotics spray
Description: 20g of multi-strain probiotics powder via colonoscopic spray. The probiotic used in this study is SynPro-15G, which has 15 probiotics, including Bacillus coagulans BC1031, Bifidobacterium bifidum BB14, Bifidobacterium breve BR18, Bifidobacterium animalis subsp. lactis BAL06, Bifidobacterium longum (B. longum) BL986, Lactobacillus acidophilus LA1063, Lactobacillus casei LC122, Lactobacillus delbrueckii subsp. lactis LDL114, Lactobacillus fermentum LF26, Lactobacillus helveticus LH43, Lactobacillus paracasei LPC12, Lactobacillus plantarum LP198, Lactobacillus reuteri LR21, Lactobacillus rhamnosus LRH10, and Streptococcus thermophilus ST37 at a concentration of 2x1010 CFU/g (Synbiotech Corp., Kaohsiung, Taiwan). SynPro-15G is made either as a vial of powder (2x1011 CFU /vial) for colonoscopic spray or as a capsule (2x1010 CFU/capsule) for oral intake.
Study: NCT05449067

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Group A and Group B
Description: Group A: Participants receive APD for 12 weeks then switch to CAPD for another 12 weeks; Group B: Participants receive CAPD for 12 weeks and switch to APD for another 12 weeks.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group A and Group B
Description: Group A: Participants receive APD for 12 weeks then switch to CAPD for another 12 weeks; Group B: Participants receive CAPD for 12 weeks and switch to APD for another 12 weeks.
Study: NCT06658756

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: internet-CBT
Description: 10 modules on line of I-CBT for OCD
Study: NCT06297213

Intervention type: DRUG
Group type: OTHER
Intervention: R-2487
Description: R-2487 DP
Study: NCT05530707

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moisturizer containing saccharide isomerate and niacinamide
Description: Moisturizer containing saccharide isomerate and niacinamide

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moisturizer containing saccharide isomerate and niacinamide
Description: Moisturizer containing saccharide isomerate and niacinamide
Study: NCT05238220

Intervention type: DRUG
Intervention: Valganciclovir
Description: continuation of valganciclovir prophylaxis up to 12 months with absence of demonstrated anti-CMV immunity
Study: NCT04278729

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5 MG
Description: 1 - 5 mg tablet taken orally twice a day

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5 MG
Description: 1 - 5 mg tablet taken orally twice a day
Study: NCT06570213

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Processing Therapy
Description: Cognitive Processing Therapy is a first-line, gold-standard psychotherapy intervention for the treatment of PTSD.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Cognitive Processing Therapy
Description: Cognitive Processing Therapy is a first-line, gold-standard psychotherapy intervention for the treatment of PTSD.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Stellate Ganglion Block
Description: Stellate Ganglion Blocks are an injection of local anesthetic into the stellate ganglion, a collection of nerves in the side of the neck.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Stellate Ganglion Block
Description: Stellate Ganglion Blocks are an injection of local anesthetic into the stellate ganglion, a collection of nerves in the side of the neck.
Study: NCT05031455

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin Challenge
Description: Dupilumab is a fully human monoclonal antibody that blocks the receptor component for IL-4 and IL-13, which are key drivers of type 2 inflammation. All subjects will be prescribed this at standard 300mg subcutaneous dosing every 2 weeks. The intervention will be the response to aspirin challenge.~All 16 subjects will receive dupilumab. All subjects will undergo an aspirin challenge/desensitization procedure. It is estimated that 50% of subjects will have a respiratory reaction to aspirin and 50% will not. There will not be any randomization.
Study: NCT06054633

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: L-arginine tablet
Description: L-arginine, 2 g, three times daily, for 12 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet
Description: Identical inert placebo, three times daily, for 12 weeks
Study: NCT05843773

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low Load Strength Training under Blood Flow Restriction
Description: The first training includes one initiation/warm up set and two sets of normal training. Every set lasts 60 seconds and the patient is asked to bend and stretch the knee with a standard speed of 20°/s.~From the second to the ninth training, the patient will have one warm up set plus three trainings sets. The speed of execution will be increased every training.~The 20-40% range of the 1RM will be applied according to the values of the theoretical maximal strength.~If no strength progression is observed in the three last training sessions, the speed of execution will automatically be increased by 15°/s.~In order to keep the training intensity low and to not overload the knee, participants will be instructed to control the intensity with the Borg CR10. The volunteers will have to keep their efforts between 2/10 and 4/10. They will also be asked to stay in the range defined thanks to the theoretical maximal strength shown by the screen.
Study: NCT04563481

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hand Therapy via Telerehabilitation
Description: stretching exercises; all finger joints, wrist and supination-pronation direction strengthening exercises; finger and wrist functional exercises retrograde massage; starting from the distal phalanx to the elbow sensory education; desentilation training (cotton...) breathing exercises 5 days / week, 8 weeks in total~* 3 days / week with physiotherapist~* 2 days / week as home program 30 minutes / day 12 repetitions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hand Therapy by Physiotherapist
Description: stretching exercises; all finger joints, wrist and supination-pronation direction strengthening exercises; finger and wrist functional exercises retrograde massage; starting from the distal phalanx to the elbow sensory education; desentilation training (cotton...) breathing exercises 5 days / week, 8 weeks in total~* 3 days / week with physiotherapist~* 2 days / week as home program 30 minutes / day 12 repetitions
Study: NCT06052839

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Immunotherapy that works by helping the immune system to kill cancer cells by targeting and blocking a protein called PD-1 on the surface of certain immune cells called T-cells. Blocking PD-1 triggers the T-cells to find and kill cancer cells.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: A chemotherapy drug that contains the metal platinum. It stops or slows the growth of cancer cells and other rapidly growing cells by damaging their DNA.
Study: NCT06674616

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Replicating Effective Programs
Description: Replicating Effective Programs (REP), based on Social Learning Theory and Rogers' Diffusion of Innovations, incorporates program packaging, training, and technical support

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Replicating Effective Programs
Description: Replicating Effective Programs (REP), based on Social Learning Theory and Rogers' Diffusion of Innovations, incorporates program packaging, training, and technical support

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Replicating Effective Programs
Description: Replicating Effective Programs (REP), based on Social Learning Theory and Rogers' Diffusion of Innovations, incorporates program packaging, training, and technical support
Study: NCT06052839

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: A chemotherapeutic agent used as a treatment for various cancers; paclitaxel is a mitotic inhibitor.
Study: NCT06674616

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Replicating Effective Programs
Description: Replicating Effective Programs (REP), based on Social Learning Theory and Rogers' Diffusion of Innovations, incorporates program packaging, training, and technical support

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Coaching
Description: Coaching is based on the Positive Behavior Interventions and Supports model, addresses staff barriers by building implementers' evidence-based practice (EBP) knowledge, self-efficacy, and skills through clinical support and feedback.
Study: NCT06387732

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: This will be delivered by coaches in a small group class format. Participants will complete the trial in staggered cohorts, with no more than six participants per class. Intervention activities will be tailored to each individual's own ability and fitness level.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stretching and relaxation
Description: This will be delivered by coaches in a small group class format. Participants will complete the trial in staggered cohorts, with no more than six participants per class. Intervention activities will be tailored to each individual's own ability and fitness level.