TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06284681

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight-focused health coaching
Description: Following the definition of structured lifestyle interventions within the current obesity clinical practice guidelines, the weight-focused health coaching intervention will be delivered as a multi-component behavior change intervention intended to produce clinically-important weight loss through consuming a healthy, energy-restricted diet and increasing physical activity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight-focused health coaching
Description: Following the definition of structured lifestyle interventions within the current obesity clinical practice guidelines, the weight-focused health coaching intervention will be delivered as a multi-component behavior change intervention intended to produce clinically-important weight loss through consuming a healthy, energy-restricted diet and increasing physical activity.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight-neutral health coaching
Description: Dietary and physical activity prescriptions for the weight-neutral health coaching intervention will be similar to the weight-focused intervention except the diet prescription will be designed to fully meet daily estimated energy requirements rather than creating a negative energy balance and producing weight loss. Health coaches will not emphasize changes in body weight as an explicit goal or as a mediator of improved cardiometabolic health. Rather, health coaches will emphasize achieving diet and exercise behavioral goals as a direct means to improving cardiometabolic health independently of changes in body weight.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight-neutral health coaching
Description: Dietary and physical activity prescriptions for the weight-neutral health coaching intervention will be similar to the weight-focused intervention except the diet prescription will be designed to fully meet daily estimated energy requirements rather than creating a negative energy balance and producing weight loss. Health coaches will not emphasize changes in body weight as an explicit goal or as a mediator of improved cardiometabolic health. Rather, health coaches will emphasize achieving diet and exercise behavioral goals as a direct means to improving cardiometabolic health independently of changes in body weight.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensify lifestyle approach
Description: Participants identified as non-responders to initial health coaching interventions may be re-randomized to receive a 4-month membership to the local YMCA and health coaches will assist participants in identifying and enrolling in at least 2 weekly group fitness classes at the YMCA.
Study: NCT03324529

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tako Breath
Description: Device guided breathing. A medical device with a computerized control unit, a breathing sensor and a set of earphones with audio-prompts to guide breathing at a slow rate (\<10 breaths/min) with prolonged exhalation.
Study: NCT05338294

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic splenectomy and azygoportal disconnection
Description: Laparoscopic splenectomy and azygoportal disconnection is performed by the same surgical team.
Study: NCT05560204

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Combined Pulsed-field Ablation (PFA) + Left Atrial Appendage Occlusion (LAAO)
Description: Pulsed-field ablation (PFA) is a non-thermal ablation technology that uses high amplitude pulsed electrical fields to ablate tissues through the mechanism of irreversible electroporation~Percutaneous LAA Occlusion (LAAO) has been emerged as an alternative to oral anticoagulants for stroke prophylaxis in patients who refused or contraindicated to OAC

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Combined Pulsed-field Ablation (PFA) + Left Atrial Appendage Occlusion (LAAO)
Description: Pulsed-field ablation (PFA) is a non-thermal ablation technology that uses high amplitude pulsed electrical fields to ablate tissues through the mechanism of irreversible electroporation~Percutaneous LAA Occlusion (LAAO) has been emerged as an alternative to oral anticoagulants for stroke prophylaxis in patients who refused or contraindicated to OAC
Study: NCT04738734

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CellFX System Device
Description: The CellFX System utilizes non-thermal, localized delivery of a timed series of low energy, nanosecond electrical pulses that can trigger regulated cell death.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cryosurgery Liquid Nitrogen Sprayer
Description: Cryosurgery will be standardized across all investigational sites using the Brymill Cry-Ac spray canister with standard cryoprobe.
Study: NCT06271486

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pregabalin 75mg
Description: Group A (pregabalin group) received oral pregabalin treatment administered at 150 mg daily, with 75 mg given every 12 hours.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: An epidural blood patch (EBP)
Description: Group B (EBP group) received active therapy in the form of an EBP

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: conservative treatment.
Description: Group C (control group) received conservative treatment providing recommendations to the patients, including 24 hours of bed rest, stool softener, and consuming a minimum of 2.0 liters of fluid daily. Analgesics were permitted for pain relief depending on the patient's disease status.
Study: NCT05626543

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavior therapy (CBT) and Mindfulness-based stress reduction (MBSR) programs
Description: Cognitive behavior therapy (CBT) and Mindfulness-based stress reduction (MBSR) programs will be used combinedly. CBT will be constructed based on the CBT model of Beck, (2021) and mindfulness practice will be implemented based on the MBSR program developed by Williams et. al. (2011).
Study: NCT05144386

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: EBT-101
Description: EBT-101 is a HIV-1-specific clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing system delivered by adenovirus-associated virus vector serotype 9 (AAV9) for intravenous (IV) administration

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: EBT-101
Description: EBT-101 is a HIV-1-specific clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing system delivered by adenovirus-associated virus vector serotype 9 (AAV9) for intravenous (IV) administration
Study: NCT05178394

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Weightlifting belts and wrist straps
Description: The participants wore a weightlifting belt (Heavywear Nylon Contour Belt H9, North Carolina, USA) for the with weightlifting belt conditions and/or put on a pair of wrist straps (Versa Gripps Professional Series, Versa Gripps, Maine, USA) for the with wrist strap conditions. The steps involved in completing a conventional deadlift have been detailed in Holmes.
Study: NCT06331962

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: remote home-based exercise therapy group
Description: Location and Frequency: Four times per week at the individual's ownhome. Exercise Duration: Eight weeks (subject to adjustments based onactual progress), with a total exercise time of 40 minutes each session.~Exercise Components: Cardiovascular endurance exercise, resistancetraining, sensory exercises.~Note: The participant will receive a customized exercise plan based ontheir capabilities, including guidelines and exercise instructions (exercisenames, required equipment, movement sequences, repetitions,precautions).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: supervised exercise therapy group
Description: Exercise Location and Frequency: Physiotherapy Center (twice a week)and individual's home (twice a week).~Exercise Duration: Eight weeks (subject to adjustments based on actualprogress), with a total exercise time of 40 minutes each session.~Exercise Components: Cardiovascular endurance exercise, resistancetraining, sensory training exercises. The home-based exercise trainingcontent is partially the same as the remote home-based exercise group.

Intervention type: OTHER
Group type: OTHER
Intervention: regular care group
Description: Perform regular care for eight consecutive weeks. After the trackingperiod ends (8 weeks), provide home-based education on resistanceexercises, cardiovascular endurance exercises, and sensory trainingexercises.
Study: NCT06630793

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: IMPT (Intensity Modulated Proton Therapy)
Description: Proton therapy is a form of radiation treatment in which high doses can be delivered within the tumour while relatively sparing the surrounding normal tissues. This may help further reduce the side-effects of radiation treatment observed with IMRT.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: IMRT (Intensity Modulated Radiation Therapy)
Description: The standard management of carcinoma of the anal canal is radiotherapy using the IMRT technique along with concurrent chemotherapy. The use of IMRT has reduced the treatment-related side-effects as compared to older radiation techniques. However, further reducing these side effects poses a major challenge.
Study: NCT06629129

Intervention type: DRUG
Group type: OTHER
Intervention: Latanoprost (0.005%)
Description: MEAN OCULAR PERFUSION PRESSURE WAS MEASURED AND CORRELATED TO THE IOP AND OPTIC NERVE PERFUSION IN RESPONSE TO LATANOPROST TREATMENT
Study: NCT05231681

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
Description: Eye Concealer
Study: NCT06284681

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensify lifestyle approach
Description: Participants identified as non-responders to initial health coaching interventions may be re-randomized to receive a 4-month membership to the local YMCA and health coaches will assist participants in identifying and enrolling in at least 2 weekly group fitness classes at the YMCA.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augment with enhanced medical management
Description: Participants identified as non-responders to initial health coaching interventions may be re-randomized to meet with the primary care provider and health coach to consider additional or revised medication plans to address their weight and weight-related chronic conditions.
Study: NCT05288413

Intervention type: DEVICE
Intervention: 3-compression Ultrasound scan with AutoDVT software integrated Ultrasound probe
Description: The study coordinator, Miss Kerstin Saupe will perform a three-point compression ultrasound scan (USS) of the upper leg with the AutoDVT software. The AutoDVT software will store the results of the scan for retroperspective analysis and review. Effectiveness of AutoDVT as diagnostic tool will be evaluated in perspective to different patient groups, eg. patients with adipositas or maligner disease,

Intervention type: DEVICE
Intervention: 3-compression Ultrasound scan with AutoDVT software integrated Ultrasound probe
Description: The study coordinator, Miss Kerstin Saupe will perform a three-point compression ultrasound scan (USS) of the upper leg with the AutoDVT software. The AutoDVT software will store the results of the scan for retroperspective analysis and review. Effectiveness of AutoDVT as diagnostic tool will be evaluated in perspective to different patient groups, eg. patients with adipositas or maligner disease,
Study: NCT06228885

Intervention type: BEHAVIORAL
Intervention: handwriting experiment and motor ability test
Description: Participants will be instructed to participate in a handwriting experiment, which involves utilizing a Force Acquisition Pen (FAP) system and Near Infrared Spectroscopy (NIRS) to collect force data and cortical activation, respectively, during handwriting tasks. Children will be tasked with completing various assignments, such as tracing lines, writing numbers, and characters, among others. Additionally, assessments of motor ability and handwriting proficiency will be conducted using the Movement Assessment Battery for Children (MABC) and the Chinese Handwriting Evaluation Form (CHEF). The Pinch Holding Up Activity (PHUA) Test will also be administered to assess their sensorimotor ability.

Intervention type: BEHAVIORAL
Intervention: handwriting experiment and motor ability test
Description: Participants will be instructed to participate in a handwriting experiment, which involves utilizing a Force Acquisition Pen (FAP) system and Near Infrared Spectroscopy (NIRS) to collect force data and cortical activation, respectively, during handwriting tasks. Children will be tasked with completing various assignments, such as tracing lines, writing numbers, and characters, among others. Additionally, assessments of motor ability and handwriting proficiency will be conducted using the Movement Assessment Battery for Children (MABC) and the Chinese Handwriting Evaluation Form (CHEF). The Pinch Holding Up Activity (PHUA) Test will also be administered to assess their sensorimotor ability.
Study: NCT06391385

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: protective ileostomy
Description: Preparation of the bowel was performed before surgery with the administration of intravenous perioperative antibiotic prophylaxis. The surgical procedure was performed by laparotomy, with resection of the rectum and mesorectum (TME) up to the level of the pelvic diaphragm, sparing the autonomic nerves. End-to-end anastomosis was performed either with a stapler or by hand-sewn.
Study: NCT06284681

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Augment with enhanced medical management
Description: Participants identified as non-responders to initial health coaching interventions may be re-randomized to meet with the primary care provider and health coach to consider additional or revised medication plans to address their weight and weight-related chronic conditions.
Study: NCT04098146

Intervention type: PROCEDURE
Intervention: Surgical Resection and Reconstruction
Description: One stage reconstruction: Osseous reconstruction is performed in the same surgery of the tumor/mandibular resection. It is also known as immediate or primary reconstruction.~Second stage reconstruction: Osseous reconstruction is performed after the tumor/mandibular resection surgery as an independent surgery. After the mandibular resection a temporary alloplastic bridging might be put in place. It is also known as delayed or secondary reconstruction.
Study: NCT05534490

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: therapatic Foot massaje (sweden technic)
Description: Everything is explained to the individuals on the day of surgery. After the surgery, when the individuals regains consciousness in the service, the Swedish massage technique is applied bilaterally for 10 minutes. In addition to the demographic data of the patient before the application and in the preoperative period; pain, mental level, delirium status, mobility, kinesiophobia, balance, and functional independence level measurement evaluations are made. Massage is continued for a total of 20 minutes, 10 minutes for each foot, once a day until the patient is discharged. The measurements are repeated on the day the individual will be discharged.
Study: NCT06300437

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: jaw thrust
Description: children who will receive jaw thrusting during fiberoptic intubation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: control (sub laxed jaw)
Description: children who will not receive jaw thrusting (just sub laxed open mouth)
Study: NCT05555329

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide 4 mg every day in cycle 1
Description: Pomalidomide 4 mg every day, on days 1-21 in a cycle of 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide 4 mg every day in cycle 1
Description: Pomalidomide 4 mg every day, on days 1-21 in a cycle of 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide 4 mg every other day in cycle 2
Description: Pomalidomide 4 mg every other day, on days 1-21 in a cycle of 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide 2 mg every day in cycle 2
Description: Pomalidomide 2 mg every day, on days 1-28 in a cycle of 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide 2 mg every day in cycle 3
Description: Pomalidomide 2 mg every day, on days 1-28 in a cycle of 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide 4 mg every other day in cycle 3
Description: Pomalidomide 4 mg every other day, on days 1-21 in a cycle of 28 days
Study: NCT03975946

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rheopheresis procedure
Description: Rheopheresis is performed using an automated monitor in a double-filtration cascade. Plasma purify from of high molecular weight proteins through a secondary filter is then returned to the patient. This technique is performed in tandem with a hemodialysis monitor.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood Sample
Description: Biological analysis
Study: NCT05910294

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: questionnaires
Description: Vaginal Assessment Scale (VAS) \& Vulvar Assessment Scale (VuAS) Breast survivorship Tool (MSK Engage Symptom Assessment) Female Sexual Function Index (FSFI) Sexual Activity Questionnaire (SAQ) Female Sexual Distress Scale Revised (FSDS-R) Menopausal Symptom Check List (MSCL) Patient-reported Outcomes Measurement Information System Sexual Function Instrument (PROMIS-SF) Weekly Non-Hormonal Moisturizer Diary

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: questionnaires
Description: Vaginal Assessment Scale (VAS) \& Vulvar Assessment Scale (VuAS) Breast survivorship Tool (MSK Engage Symptom Assessment) Female Sexual Function Index (FSFI) Sexual Activity Questionnaire (SAQ) Female Sexual Distress Scale Revised (FSDS-R) Menopausal Symptom Check List (MSCL) Patient-reported Outcomes Measurement Information System Sexual Function Instrument (PROMIS-SF) Weekly Non-Hormonal Moisturizer Diary

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: moisturizers
Description: Patients will be provided a list of recommended moisturizers by the female sexual medicine and women's health program (FSMWHP), but will purchase the moisturizers themselves at their local pharmacy.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: moisturizers
Description: potential vaginal moisturizers include Hyalogyn, Replens, Liquibeads, or Vitamin E capsules
Study: NCT06188286

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous electrical acupoint stimulation
Description: The 4 patches of the transcutaneous acupoint electrical stimulator were pasted on two pairs of acupuncture points, the output frequency was adjusted to 2Hz, the intensity was up to 50ma, the single intervention time was 30 minutes, and another group of acupuncture points was replaced after completion, and the rest of the operations were the same as above, with a total intervention time of 1 hour.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: sham Transcutaneous electrical acupoint stimulation
Description: The patch is fixed on the acupuncture point to turn on the instrument, but there is no current output
Study: NCT05985005

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: online simulation of high alert medication safety training
Description: online simulation of high alert medication safety training
Study: NCT06022822

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy
Study: NCT06407999

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Expiratory Pressure Relief
Description: EPR is a function used in CPAP intended to improve comfort by reducing delivered pressure during the expiratory phase. When EPR is not used, the patient receives true CPAP.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Expiratory Pressure Relief
Description: EPR is a function used in CPAP intended to improve comfort by reducing delivered pressure during the expiratory phase. When EPR is not used, the patient receives true CPAP.
Study: NCT05955937

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enhanced HF Clinical Care (Core-HF)
Description: All clinical care providers involved in HF care at participating RRHs will be trained in a HF service bundle including a care protocol (treatment algorithm based on global guidelines), self-care training for patients and providers, and medication stock management to ensure supply of HF medications to patients in need.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital health intervention (Medly Uganda) plus enhanced HF clinical care (Core-HF)
Description: A patient-facing mobile health application designed to improve self-care will be provided to the study participant, which will operate on all mobile devices. This will be introduced after the Core-HF intervention has been delivered.
Study: NCT05609695

Intervention type: DRUG
Intervention: Immune checkpoint inhibitor
Description: After signing the written informed consent form, patients begin to receive single or combined therapy with immune checkpoint inhibitor. The use of immune checkpoint inhibitors takes 3 weeks as a cycle, and the treatment dose for each cycle is carried out in accordance with the latest international authoritative guidelines.
Study: NCT06336967

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GUIDE
Description: The GUIDE App is a wellbeing app designed for first responders and veterans that uses small group support, a learning management system, drivers of behavior change, and an anonymous member experience safeguarded by a leader in identity and login privacy, Okta (okta.com). It includes three main features: 1) Community, 2) Wisdom, and 3) Daily Practice. The Community feature connects app users with an online community of like folks, allowing for human support, encouragement, accountability and coaching. Online communities are moderated by GUIDE employees. The Wisdom feature includes tools and interactive media for personal growth. The Daily Practice feature includes simple, daily routines to maintain mental and emotional wellness.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GUIDE
Description: The GUIDE App is a wellbeing app designed for first responders and veterans that uses small group support, a learning management system, drivers of behavior change, and an anonymous member experience safeguarded by a leader in identity and login privacy, Okta (okta.com). It includes three main features: 1) Community, 2) Wisdom, and 3) Daily Practice. The Community feature connects app users with an online community of like folks, allowing for human support, encouragement, accountability and coaching. Online communities are moderated by GUIDE employees. The Wisdom feature includes tools and interactive media for personal growth. The Daily Practice feature includes simple, daily routines to maintain mental and emotional wellness.