Study: NCT06534307

Intervention type: DIAGNOSTIC_TEST
Intervention: metabolic examination
Description: metabolic development using blood analysis including blood components, metabolic parameters (Glucose, HbA1c, cholestrol)

Intervention type: DIAGNOSTIC_TEST
Intervention: metabolic examination
Description: metabolic development using blood analysis including blood components, metabolic parameters (Glucose, HbA1c, cholestrol)

Intervention type: BEHAVIORAL
Intervention: Questionnaire Reynolds Intellectual Assessment Scales and Screening
Description: The RIAS is standardized intelligence test. The RIAS provides an Total Intelligence Index (GIX, estimate of the general intelligence/g-factor), Verbal Intelligence Index (VIX) and the Nonverbal Intelligence Index (NIX). Test scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean better cognitive performance.

Intervention type: BEHAVIORAL
Intervention: Questionnaire Reynolds Intellectual Assessment Scales and Screening
Description: The RIAS is standardized intelligence test. The RIAS provides an Total Intelligence Index (GIX, estimate of the general intelligence/g-factor), Verbal Intelligence Index (VIX) and the Nonverbal Intelligence Index (NIX). Test scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean better cognitive performance.

Intervention type: DIAGNOSTIC_TEST
Intervention: electroencephalogram
Description: neurocognitive development

Intervention type: DIAGNOSTIC_TEST
Intervention: electroencephalogram
Description: neurocognitive development

Intervention type: OTHER
Intervention: Questionnaire Movement Assessment Battery for Children
Description: The M-ABC-2 is an standardized test to assess the motoric development. Adding up subscores addressing manual dexterity, aiming and catching, and balance delivers a total score of the motoric performance.~Test scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean better performance.

Intervention type: OTHER
Intervention: Questionnaire Movement Assessment Battery for Children
Description: The M-ABC-2 is an standardized test to assess the motoric development. Adding up subscores addressing manual dexterity, aiming and catching, and balance delivers a total score of the motoric performance.~Test scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean better performance.

Intervention type: OTHER
Intervention: Questionnaire Continuous Performance Test
Description: The CPT measures selective attention, sustained attention as well as impulsive behavior. Checklist scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean worse performance.

Intervention type: OTHER
Intervention: Questionnaire Continuous Performance Test
Description: The CPT measures selective attention, sustained attention as well as impulsive behavior. Checklist scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean worse performance.

Intervention type: OTHER
Intervention: Questionnaire Diagnostic System for Mental Disorders
Description: The FBB-ADHS assesses a total score for ADHD-like behavior and subscores for the symptom trias of ADHD (attention deficit, motoric hyperactivity as well as impulsive behavior, Questionnaire scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean higher amount of symptoms.

Intervention type: OTHER
Intervention: Questionnaire Diagnostic System for Mental Disorders
Description: The FBB-ADHS assesses a total score for ADHD-like behavior and subscores for the symptom trias of ADHD (attention deficit, motoric hyperactivity as well as impulsive behavior, Questionnaire scores are reported on a T-scale. Range of T-scale from scores 20 to 100 (average performance between scores 40 and 60). Higher scores mean higher amount of symptoms.

Intervention type: DIAGNOSTIC_TEST
Intervention: kidney function tests
Description: urine examination (proteomics, cytokines, lipidomics)

Intervention type: DIAGNOSTIC_TEST
Intervention: kidney function tests
Description: urine examination (proteomics, cytokines, lipidomics)

Intervention type: OTHER
Intervention: Questionnaire Five to Fifteen
Description: The FTF 5-15R is a questionnaire to evaluate the child's developmental outcome in different areas of everyday life (cognition, language, and motor impairment as well as social, emotional, and behavioral problems). Individual item scores are added up per area and divided by the number of items. This results in a common scale value. Range of Percentile scores from 0 to 100 (0-90: no developmental problem; 90 and higher: hint for developmental problem). Higher scores mean worse developmental outcome.

Intervention type: OTHER
Intervention: Questionnaire Five to Fifteen
Description: The FTF 5-15R is a questionnaire to evaluate the child's developmental outcome in different areas of everyday life (cognition, language, and motor impairment as well as social, emotional, and behavioral problems). Individual item scores are added up per area and divided by the number of items. This results in a common scale value. Range of Percentile scores from 0 to 100 (0-90: no developmental problem; 90 and higher: hint for developmental problem). Higher scores mean worse developmental outcome.

Intervention type: DIAGNOSTIC_TEST
Intervention: cardiovacular examination
Description: measurement of pulse wave velocity

Intervention type: DIAGNOSTIC_TEST
Intervention: cardiovacular examination
Description: measurement of pulse wave velocity