TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05609162

Intervention type: PROCEDURE
Intervention: neurosurgical resection
Description: neurosurgical resection, stereotactic radiosurgery (SRS), whole brain radiotherapy(WBRT), EGFR target drugs, Immune checkpoint inhibitors，cisplatin, temozolomide

Intervention type: PROCEDURE
Intervention: neurosurgical resection
Description: neurosurgical resection, stereotactic radiosurgery (SRS), whole brain radiotherapy(WBRT), EGFR target drugs, Immune checkpoint inhibitors，cisplatin, temozolomide

Intervention type: PROCEDURE
Intervention: neurosurgical resection
Description: neurosurgical resection, stereotactic radiosurgery (SRS), whole brain radiotherapy(WBRT), EGFR target drugs, Immune checkpoint inhibitors，cisplatin, temozolomide

Intervention type: PROCEDURE
Intervention: neurosurgical resection
Description: neurosurgical resection, stereotactic radiosurgery (SRS), whole brain radiotherapy(WBRT), EGFR target drugs, Immune checkpoint inhibitors，cisplatin, temozolomide

Intervention type: PROCEDURE
Intervention: neurosurgical resection
Description: neurosurgical resection, stereotactic radiosurgery (SRS), whole brain radiotherapy(WBRT), EGFR target drugs, Immune checkpoint inhibitors，cisplatin, temozolomide
Study: NCT06189729

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Text reminder
Description: Participants will receive trimonthly text reminders through instant messaging mobile applications or short message service.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Text reminder
Description: Participants will receive trimonthly text reminders through instant messaging mobile applications or short message service.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Text reminder
Description: Participants will receive trimonthly text reminders through instant messaging mobile applications or short message service.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: HIV self-test
Description: Participants will receive trimonthly text messages asking them to choose a pickup point run by the delivery company to collect the free HIV self-test. Upon receiving the delivery instruction, the self-test kit with bilingual (Chinese and English) instructions would be delivered to the designated location.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: HIV self-test
Description: Participants will receive trimonthly text messages asking them to choose a pickup point run by the delivery company to collect the free HIV self-test. Upon receiving the delivery instruction, the self-test kit with bilingual (Chinese and English) instructions would be delivered to the designated location.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: HIV self-test
Description: Participants will receive trimonthly text messages asking them to choose a pickup point run by the delivery company to collect the free HIV self-test. Upon receiving the delivery instruction, the self-test kit with bilingual (Chinese and English) instructions would be delivered to the designated location.
Study: NCT04819334

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Composition of Sports Drink
Description: The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Composition of Sports Drink
Description: The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid.
Study: NCT05099341

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HDRS-17 depression scale
Description: Measuring the severity of depression

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood sampling
Description: 3 tubes of 5 ml

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: 3 tubes of 5 ml

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: 3 tubes of 5 ml
Study: NCT04819334

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Composition of Sports Drink
Description: The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid.
Study: NCT05984160

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Paragastric neural block
Description: A block method used to control patients' symptoms of pain, nausea and vomiting after surgery.
Study: NCT05329701

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Individualized treatment duration strategy
Description: As listed under arm description.
Study: NCT00519402

Intervention type: OTHER
Intervention: tonsillar examination and questionnaire completion

Intervention type: OTHER
Intervention: tonsillar examination and questionnaire completion
Study: NCT06534554

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Navigation
Description: A lay patient navigator working will contact patients seen in the UAB ED via phone within \~72 hours following the ED visit. During this initial phone conversation, the navigators will: 1) conduct a baseline assessment to identify barriers to attending an outpatient visit for gout care and to adhering to gout treatment recommendations and 2) determine the level of support and assistance needed by the patient.
Study: NCT05844111

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-BGB-11417
Description: A single oral dose of liquid formulation
Study: NCT06326008

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy
Description: Peripheral blood mononuclear cells for the production of CD19 CAR T cells and CD22 CAR T cells are collected from donors and haematopoietic stem cells are collected from donors.
Study: NCT05246761

Intervention type: DEVICE
Intervention: Balloon catheter
Description: In the two groups, if their bishop score \<6, they will receive the cervical riening by the balloon catheter, and then the oxytocin if necessary.

Intervention type: DEVICE
Intervention: Balloon catheter
Description: In the two groups, if their bishop score \<6, they will receive the cervical riening by the balloon catheter, and then the oxytocin if necessary.
Study: NCT05537272

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tadalafil 5mg
Description: Administration of Tadalafil 5mg once daily seven days before and seven days after prostate biopsy

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tamsulosin Hydrochloride 400 Microgram Prolonged-Release Oral Capsule
Description: Administration of Tamsulosin 0.4mg once daily seven days before and seven days after prostate biopsy

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administration of placebo ( Vitamin C \[ascorbic acid\] 500mg tablet) once daily seven days before and seven days after prostate biopsy
Study: NCT04781725

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INT230-6
Description: INT230-6 is a formulation of two well known chemotherapeutic agents, cisplatin (0.5mg/mL) and vinblastine sulfate (0.1mg/mL), combined with 2-hydroxybenzoylaminooctanoate (also known as SHAO-FA or SHAO as a sodium salt at 10mg/mL).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline injection
Description: Standard 0.9 % NaCl Normal Saline

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Saline injection
Description: Standard 0.9 % NaCl Normal Saline
Study: NCT06161324

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PFM exercises program through the Mobile app in cooperation with the superficial sensor
Description: The mobile app will offer a personalized progressive protocol to the user based on his needs, via 12 levels of games(from the easiest to the hardest).The cooperating PFM superficial sensor will indicate the activity of the PFMs during the contraction.Νο face-to-face meetings will be incurred between participants and therapist.~Participants will follow a program for 12 weeks(3 times weekly, 1-5 sessions daily, each session's duration approximately 20 minutes).Endurance training will involve slow velocity contraction and speed training will involve quick (i.e.1 sec duration) strong contractions.Knack maneuver training will contain a pre-contraction before the increment of the intra-abdominal pressure during coughing. The exercise positions will change every 2 weeks (supine, side, prone, quadruped support, sitting and standing position).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Face-to face PFM exercises program in Healthcare environment
Description: The therapy will include face-to-face meetings weekly, regarding the progress of the treatment and its smooth transition (intra-vaginally assessment when it needs, correction, encouragement, motivation, etc).~Participants will follow a personalized progressive PFM exercise program for 12 weeks (3 times weekly, 1-5 sessions daily, each session's duration approximately 20 minutes).The endurance training will involve slow velocity contraction and the speed training will involve quick (i.e.1 sec duration) strong contractions. The Knack maneuver training will contain a pre-contraction before the increment of the intra-abdominal pressure during coughing. The exercise positions will change every 2 weeks.It will be followed the order of supine, side, prone, quadruped support, sitting and standing position

Intervention type: OTHER
Group type: OTHER
Intervention: PFM exercises program via home-leaflet(without suprevision)
Description: The participants of the CG will be advised to follow a personalized PFM exercise program at home based on their 1st meeting assessment. They will receive a comprehensive leaflet, with instructions and images about the PFM exercises at home. The PFM exercise program will last 12 weeks (3 times weekly, 1-5 sessions daily), without meetings, guidance and supervision by the physiotherapist. Similarly to the other two intervention groups, the program will contain endurance training (slow velocity contraction), speed training (quick contractions), Knack maneuver training (pre-contraction before coughing), and changing positions every 2 weeks (supine, side, prone, quadruped support, sitting and standing position)
Study: NCT06189625

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: All patients included in the study, both in the non-bandaging group and in the bandaging group, will receive a series of general measures as a recommendation, consisting of the following:~* Administration of anti-inflammatory drugs as ibuprofen at 7.5 mg/kg/8 hours for 2-3 days. If pain continues, recommendation of paracetamol 15 mg/kg 4 hours after ibuprofen.~* Application of local ice for a maximum of 10 minutes as required.~* Elevation of the affected limb when resting.~* Early mobilization and load according to tolerance, using crutches if required.~* Sports rest at least for one week or until the patient is able to walk without pain, with gradual incorporation according to tolerance. During the following year, use of elastic ankle brace for sports activities.~The control group will not receive any special intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: All patients included in the study, both in the non-bandaging group and in the bandaging group, will receive a series of general measures as a recommendation, consisting of the following:~* Administration of anti-inflammatory drugs as ibuprofen at 7.5 mg/kg/8 hours for 2-3 days. If pain continues, recommendation of paracetamol 15 mg/kg 4 hours after ibuprofen.~* Application of local ice for a maximum of 10 minutes as required.~* Elevation of the affected limb when resting.~* Early mobilization and load according to tolerance, using crutches if required.~* Sports rest at least for one week or until the patient is able to walk without pain, with gradual incorporation according to tolerance. During the following year, use of elastic ankle brace for sports activities.~The control group will not receive any special intervention.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Functional bandage
Description: The functional bandage will consist of a standardized wrapping in several phases. First, with 6 mm silk tape, open anchors were placed in the distal region of the metatarsals of the foot and in the middle third of the affected leg. Next, a strip of tape was applied in stirrup fashion, starting from the proximal anchor and exerting pressure cranially on the side of the affected ligament. This support was interspersed three times with another strip of tape, starting from the foot anchor and wrapping behind the ankle. Once complete, it was covered with a 7.5 cm Tensoplast spiral bandage, taking care to apply gentle pressure. The emergency nurses underwent dual training, consisting of an instructional video and a half-hour practical session. Reminder posters were also displayed in the technique box where such procedures are typically performed.~As the control group, general measures will be recommended.
Study: NCT05589623

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Copenhagen adduction exercise
Description: The CAE is a progressive eccentric training program that enhances hip adduction. The fact that exercises are done with a partner and do not require special equipment makes them more useful in a team setting. The MPCA program, adapted from the original CAE, included six progressive levels for eight weeks, beginning with an assisted isometric adduction hold (level 1) and progressing incrementally to a complete CAE as the original exercise (level 6). The progression in levels will depend on a pain score ≤ 4/10 numeric rating scale (NRS) in the adductor squeeze test and post-session DOMS score ≤ 4/10 NRS.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual rehabilitation program
Description: The usual rehabilitation program will include leg swings extension/flexion, leg swings abduction/adduction, standing hip circles, isometric standing hip adduction using elastic bands, stretching exercises, balance training on a wobble board, and single leg coordination exercises. Difficulty and volume are progressing incrementally.
Study: NCT04603690

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Complementary therapy
Description: A daily supplementation of 168 mg curcumin, 260 mg quercetin and 360 IU of vitamin D3 (cholecalciferol) for 14-days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of care
Description: This arm will receive standard of care as per the hospital guidelines

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: This arm will receive standard of care as per the hospital guidelines
Study: NCT05639426

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally Responsive Practices (CRP)
Description: The CRP component of the intervention targets pedagogy, curriculum, and potential teacher biases and discriminatory behavior. This component will consist of two intensive 4-hour workshops delivered by Morton and Billingsley in each school's first intervention year as well as one-hour annual boosters (Backpacks for Success and Culturally Relevant Pedagogy). All teachers and school administrators will participate in the workshops. The purpose of Backpacks for Success is to increase participants' awareness of structural racism, empathy for students, and motivation to change, while identifying equity targets and strategies to reach those targets. Culturally Relevant Pedagogy comprises classroom based strategies to promote equity, including use of culturally responsive curriculum, language, attitudes, and actions, with the goal of reducing interpersonal and cultural racism. Ongoing group coaching sessions will provide a space for peer support and learning around increasing CRP.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally-Responsive Schoolwide Positive Behavior Interventions and Supports (C-SWPBS)
Description: We will implement SWPBS according to the equity-focused framework established by the Center on PBIS, with an increased emphasis on community integration. SWPBS involves creating a school team of 6-10 people, including at least one administrator, teachers, and staff members. We will include at least three community stakeholders on each C-SWPBS team to integrate the culture of the community, reducing institutional and cultural racism. Community stakeholders may be parents or other invested members of the local community not employed by the school district. The school climate specialists serve on the C-SWPBS team and provide consultation for the management of violence incidents and mental health concerns.
Study: NCT05866796

Intervention type: DIAGNOSTIC_TEST
Intervention: GlycoTransplantTest
Description: Determination of serum glycomics in the early posttransplant stage, using an optimal cutoff based on statistic modeling.

Intervention type: DIAGNOSTIC_TEST
Intervention: GlycoTransplantTest
Description: Determination of serum glycomics in the early posttransplant stage, using an optimal cutoff based on statistic modeling.
Study: NCT06265012

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PHV01
Description: Marburg virus vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PHV01
Description: Marburg virus vaccine
Study: NCT05142176

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Erector spinae catheters insertion
Description: Ultrasound-Guided ESPB The ESPB will be performed with the child in a right lateral decubitus position under aseptic precautions by a high frequency (6-13 MHz) linear ultrasound transducer

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Erector spinae catheters insertion
Description: Ultrasound-Guided ESPB The ESPB will be performed with the child in a right lateral decubitus position under aseptic precautions by a high frequency (6-13 MHz) linear ultrasound transducer

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Postoperative pain management
Description: IV acetaminophen 15 mg/kg every 8 hours as a component of multimodal analgesia.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Postoperative pain management
Description: IV acetaminophen 15 mg/kg every 8 hours as a component of multimodal analgesia.
Study: NCT05908929

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SRP and concomitant insertion of PRF membrane
Description: The pockets were treated with scaling and root planing (SRP) along with the simultaneous insertion of a Platelet Rich Fibrin (PRF) membrane. Blood samples were drawn without anticoagulants in 10 mL tubes, which were immediately centrifuged at 4000 rpm for 8 minutes. Upon centrifugation, the blood showed three distinct layers: the uppermost layer contained platelet poor plasma, the middle layer consisted of a fibrin clot, and the lowermost band appeared bright red due to the presence of red blood cells. The fibrin clot polymerized in a diffuse manner within the tube, which was then cut with sharp scissors and squeezed between two glass slides to obtain a thick membrane. The PRF membrane was carefully handled using a carrier and isolated with a periodontal pack dressing (Coe-Pak). All patients were followed up at one week and six weeks after the treatment.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SRP
Description: The pockets were treated using the conventional procedure of scaling and root planing (SRP) utilizing curettes and an ultrasonic device. All patients were followed up at one week and six weeks after the treatment.
Study: NCT06265012

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PHV01
Description: Marburg virus vaccine

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Lactated Ringer's Solution
Study: NCT01996488

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olanzapine Orally Disintegrating Tablets 5mg
Study: NCT05724862

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Needle-less jet anaesthesia
Description: Infiltration anesthesia without needle depending on injection pressure

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Injection Anesthesia
Description: Regular Infiltration local anesthesia
Study: NCT05032560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABX464
Description: Drug: ABX464 ABX464 is a new anti-inflammatory drug
Study: NCT05069597

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CREON
Description: Capsule; Oral

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CREON
Description: Capsule; Oral
Study: NCT05032560

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABX464
Description: Drug: ABX464 ABX464 is a new anti-inflammatory drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABX464
Description: Drug: ABX464 ABX464 is a new anti-inflammatory drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABX464
Description: Drug: ABX464 ABX464 is a new anti-inflammatory drug

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Drug: Matching Placebo placebo matching with ABX464

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Drug: Matching Placebo placebo matching with ABX464

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Drug: Matching Placebo placebo matching with ABX464

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Drug: Matching Placebo placebo matching with ABX464
Study: NCT06409104

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: will receive 1-2 mgkg-1 propofol injection over 30s followed by of propofol a 0.05 to 0.1 mg /kg/min infusion
Study: NCT06557005

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Facilitated Transition to Primary Care
Description: The intervention includes default PCP visit scheduling, tailored nudge messages to patients, ongoing care recommendations sent to the PCP, and a summary of recommendations after pregnancy given to the patient.