TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05095727

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mRNA-3745
Description: Sterile frozen liquid dispersion for injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mRNA-3745
Description: Sterile frozen liquid dispersion for injection
Study: NCT05083884

Intervention type: OTHER
Intervention: No Intervention
Description: This is a cross-sectional non-product related survey including peri- and post-menopausal women with moderate to severe VMS associated with menopause.

Intervention type: OTHER
Intervention: No Intervention
Description: This is a cross-sectional non-product related survey including peri- and post-menopausal women with moderate to severe VMS associated with menopause.

Intervention type: OTHER
Intervention: No Intervention
Description: This is a cross-sectional non-product related survey including peri- and post-menopausal women with moderate to severe VMS associated with menopause.

Intervention type: OTHER
Intervention: No Intervention
Description: This is a cross-sectional non-product related survey including peri- and post-menopausal women with moderate to severe VMS associated with menopause.
Study: NCT04869059

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation
Description: Transcranial direct current stimulation will be delivered via a Neuroelectrics Starstim tES. Stimulation will consist of 1 milliamp stimulation, with anodal stimulation delivered at electrode Fz (International 10/10 System for electroencephalography electrode placement) and electrodes F7, FP1, FP2, and F8 as returns. All electrodes are 1 cm diameter Ag/AgCl electrodes and make contact with the scalp via connective gel. Stimulation will linearly ramp up from 0 milliamps to 1 milliamp over 60 seconds, then remain at 1 milliamp of stimulation over 20 minutes, and finally ramping down at to 0 milliamps over 60 seconds.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tDCS
Description: Sham transcranial direct current stimulation will be delivered via a Neuroelectrics Starstim tES. The sham setup will consist of anodal electrode Fz (International 10/10 System for electroencephalography electrode placement) and electrodes F7, FP1, FP2, and F8 as returns. All electrodes are 1 cm diameter Ag/AgCl electrodes and make contact with the scalp via connective gel. Stimulation will linearly ramp up from 0 milliamps to 1 milliamp over 60 seconds, ramp down to 0 milliamps over 60 seconds and then be left off for 20 minutes.
Study: NCT06540703

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Therapeutic Ketogenic Diet (TKD)
Description: 2 week induction to establish ketosis followed by 12 weeks therapeutic ketogenic diet
Study: NCT06651775

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High intensity laser therapy
Description: lumbosciatalgia mode of the HILT device

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Comparator
Description: sham mode of the HILT device
Study: NCT05709704

Intervention type: DIAGNOSTIC_TEST
Intervention: Self-palpation via telehealth
Description: This will be used to determine if the participant has the diagnosis

Intervention type: DIAGNOSTIC_TEST
Intervention: Self-palpation via telehealth
Description: This will be used to determine if the participant has the diagnosis

Intervention type: DIAGNOSTIC_TEST
Intervention: Real-time Ultrasound
Description: This will be used in a subgroup of participants to confirm/rule out a diagnosis

Intervention type: DIAGNOSTIC_TEST
Intervention: Real-time Ultrasound
Description: This will be used in a subgroup of participants to confirm/rule out a diagnosis
Study: NCT05648344

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WW
Description: WW assigns foods to a point value calculated through a proprietary algorithm that accounts for the food's caloric value, saturated and unsaturated fat, sugar, fiber, and protein. Members are encouraged to track their food and beverage intake, with the goal of staying within their personal points targets assigned based in an individual's sex, age height, weight, goals, and activity. The program also has Zero Point Foods (list of healthy foods with no point value) and can be eaten freely. In addition to the personal points, participants will be asked to attend WW coach-led virtual workshops conducted over Zoom, engage with peer- support, and WW-trained behavior change experts via 24/7 chat.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Usual care with information from myplate.gov
Study: NCT05998603

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: High protein intake
Description: The participants received a 60g whey protein bolus each evening prior to sleep pre and post a military load carriage test.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Moderate protein intake
Description: The participants received a 20g whey protein bolus each evening prior to sleep pre and post a military load carriage test.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Carbohydrate maltodextrin placebo
Description: The participants received an isocaloric carbohydrate bolus each evening prior to sleep pre and post a military load carriage test.

Intervention type: OTHER
Group type: OTHER
Intervention: Control no supplementation
Description: Control group, no supplementation, only basic training
Study: NCT05350111

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: lifestyle education
Description: education on healthy lifestyle through group sessions and telemedicine tools
Study: NCT05747664

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001
Description: 0.3mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001
Description: 0.3mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001
Description: 0.3mg
Study: NCT04853264

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided peripheral venipuncture
Description: Ultrasound-guided peripheral venipuncture performed by a proficient vascular access registered nurse. The procedure will be performed according to the standard operational protocol for ultrasound guided peripheral venipuncture instituted at the hospital where the study will be conducted. Site Rite 8 or Site Rite 5 ultrasound machines (Bard Access Systems, Inc., USA) will be used on the procedures.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional peripheral venipuncture
Description: Conventional peripheral venipuncture performed by a registered nurse at the clinical inpatient unit. The procedure will be performed according to the standard operational protocol for peripheral venipuncture instituted in the hospital where the study will be conducted.
Study: NCT06050889

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Positive Expectations Instructional Set
Description: Participants randomly assigned to this instructional set will be told, You will be completing an intervention known to be effective for some people with shoulder pain. We expect this will make you less sensitive to the pressure applied to your shoulder and thigh and you will require more pressure than what was previously necessary to experience pain.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Positive Expectations Instructional Set
Description: Participants randomly assigned to this instructional set will be told, You will be completing an intervention known to be effective for some people with shoulder pain. We expect this will make you less sensitive to the pressure applied to your shoulder and thigh and you will require more pressure than what was previously necessary to experience pain.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Negative Expectations Instructional Set
Description: Participants randomly assigned to this instructional set will be told, You will be completing an intervention which is not effective for some people with shoulder pain. We expect this will make you more sensitive to the pressure applied to your shoulder and thigh and you will require less pressure than what was previously necessary to experience pain.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Negative Expectations Instructional Set
Description: Participants randomly assigned to this instructional set will be told, You will be completing an intervention which is not effective for some people with shoulder pain. We expect this will make you more sensitive to the pressure applied to your shoulder and thigh and you will require less pressure than what was previously necessary to experience pain.
Study: NCT06341829

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prismatic adaptation
Description: Participants will fit with prismatic goggles that deviate their visual field by 13° either leftward or rightward. They will seat in front of a white horizontal board on which three target dots (5 mm diameter) were positioned at 0, -10 and +10° from their body midline at a distance of 57 cm from their eyes. They will perform a total of 150 verbally instructed pointing movements with their right index finger towards the right (+10°) and left (-10°) targets in a pseudorandom order.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Prismatic adaptation
Description: Participants will fit with prismatic goggles that deviate their visual field by 13° either leftward or rightward. They will seat in front of a white horizontal board on which three target dots (5 mm diameter) were positioned at 0, -10 and +10° from their body midline at a distance of 57 cm from their eyes. They will perform a total of 150 verbally instructed pointing movements with their right index finger towards the right (+10°) and left (-10°) targets in a pseudorandom order.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prismatic adaptation
Description: Participants will fit with prismatic goggles that deviate their visual field by 13° either leftward or rightward. They will seat in front of a white horizontal board on which three target dots (5 mm diameter) were positioned at 0, -10 and +10° from their body midline at a distance of 57 cm from their eyes. They will perform a total of 150 verbally instructed pointing movements with their right index finger towards the right (+10°) and left (-10°) targets in a pseudorandom order.
Study: NCT06315673

Intervention type: BEHAVIORAL
Intervention: Digital Speech and Handwriting Assessment
Description: Subjects may complete all or some of these tests, depending on functional ability.~* Handwriting battery~* Pattern tracing battery~* Speech Assessment Battery

Intervention type: BEHAVIORAL
Intervention: Digital Speech and Handwriting Assessment
Description: Subjects may complete all or some of these tests, depending on functional ability.~* Handwriting battery~* Pattern tracing battery~* Speech Assessment Battery
Study: NCT05492227

Intervention type: DIAGNOSTIC_TEST
Intervention: Left-overs
Description: Totally nasal swab leftovers were stored from the biobank of Hospital Puerta del Hierro. The coded specimens were kept at -80°C and analyzed using the SARS-CoV-2 NAD Kit. Previously these specimens were analyzed using the gold-standard RT-PCR.

Intervention type: DIAGNOSTIC_TEST
Intervention: Left-overs
Description: Totally nasal swab leftovers were stored from the biobank of Hospital Puerta del Hierro. The coded specimens were kept at -80°C and analyzed using the SARS-CoV-2 NAD Kit. Previously these specimens were analyzed using the gold-standard RT-PCR.
Study: NCT06340724

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vonoprazan
Description: 20 mg tablet twice daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vonoprazan
Description: 20 mg tablet twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin
Description: 1 g tablet three times daily
Study: NCT06237608

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialectical behavioural therapy (DBT)-informed skills group
Description: 16 week 1.5hr DBT-informed skills group facilitated by the lead researcher and two charity facilitators
Study: NCT06099028

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT04880460

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium Glycinate tablet 200mg
Description: Magnesium glycinate tablet 200mg twice daily orally for 8 weeks along with SSRIs

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet 200mg
Description: Placebo tablet 200mg twice daily orally for 8 weeks along with SSRIs
Study: NCT06340724

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: 1 g tablet three times daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Banxiaxiexin decotion
Description: 100 ml liquid-medicine twice daily
Study: NCT05454800

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scoliosis Specific Corrective Exercises and Physical Activity Counseling
Description: Scoliosis specific corrective exercises and physical activity counseling
Study: NCT05529862

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Pre-treatment biopsy
Description: Pre-treatment fragments will be collected during the biopsy visit organised as part of routine medical practice, prior to the start of treatment with ribociclib + ET

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Post treatment biopsy
Description: Post-treatment fragments will be collected during a biopsy visit specifically planned for Trans-RosaLEE study.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Pre treatment blood sampling
Description: Sampling of 4 EDTA Tubes (4ml) and 2 Streck tubes (10ml)

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Post treatment blood sampling
Description: Sampling of 2 Streck tubes (10ml)
Study: NCT05454800

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scoliosis Specific Corrective Exercises
Description: Only scoliosis specific corrective exercises
Study: NCT06554054

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR18
Description: Oral administered the GZR18 tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GZR18
Description: Oral administered the GZR18 tablet
Study: NCT06040385

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Implant supported hybrid prosthesis
Description: For each patient, implant supported mandibular hybrid prosthesis will be fabricated digitally. Frameworks will be tried in patient's mouth, scanned intraorally by intraoral scanner (IOS).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Implant supported hybrid prosthesis
Description: For each patient, implant supported mandibular hybrid prosthesis will be fabricated digitally. Frameworks will be tried in patient's mouth, scanned intraorally by intraoral scanner (IOS).
Study: NCT05546658

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: Psilocybin administration under supportive conditions

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin administration under supportive conditions
Study: NCT03576924

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MICT
Description: Individuals randomized to MICT will be asked to engage in only MICT 5 times/week for 30 min/session at 60-70% of heart rate max, consistent with physical activity guidelines of 150 min/week of moderate activity. Individuals are asked to engage in only MICT exercise during the 4-week supervised and unsupervised exercise sessions. During the supervised exercise the intensity will be based on the heart rate (HR) monitors and psychophysiological responses of perceived exertion. The exercise training is paired with 30-50 minutes of behavioral counselling that is identical for all three interventions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HIIT
Description: Individuals randomized to HIIT will be asked to engage in only HIIT 5 times/week for 4 weeks. HIIT consists of 5 repeated vigorous intervals of 1-min duration at 80-90% of heart rate max interspersed with 1-min recovery periods. A 3-min warm-up and 2-min cool-down are also included, for a total session duration of 15 minutes. This matches the guidelines of 75 min of vigorous exercise per week. During the supervised exercise sessions, intensity will be based on HR monitors and psychophysiological responses of perceived exertion. The exercise training is paired with 30-50 minutes of behavioral counselling that is identical for all three interventions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CHOICE
Description: Participants will first be familiarized with HIIT and MICT in a randomized, counter-balanced order during supervised sessions 1 and 2, and will subsequently self-select the exercise type for the supervised and unsupervised exercise sessions. The HIIT and MICT protocols will match to the parallel imposed conditions. During the supervised exercise, intensity will also be based on HR monitors and psychophysiological responses of perceived exertion. The exercise training is paired with 30-50 minutes of behavioral counselling that is identical for all three interventions.
Study: NCT05452070

Intervention type: DEVICE
Group type: OTHER
Intervention: HArmonyCa Lidocaine Injectable Gel
Description: Subdermal or deep dermal injection

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HArmonyCa Lidocaine Injectable Gel
Description: Subdermal or deep dermal injection
Study: NCT06272760

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based hand-arm bimanual intensive training (Tele-HABIT)
Description: Hand-Arm Bimanual Intensive Therapy (HABIT) is a therapeutic approach designed to improve the motor skills and functional use of both arms in individuals with conditions such as cerebral palsy. The core principle of HABIT is to encourage voluntary exercise by actively engaging the affected side, which may be weaker or partially paralyzed, in various activities. This approach aims to reduce physical and mental discomfort while maximizing the effectiveness of the training. HABIT has been adapted into a home-based format by ZOOM, referred to as Home-Based HABIT (H-HABIT).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hand-arm bimanual intensive training (In-clinic-HABIT)
Description: Hand-Arm Bimanual Intensive Therapy (HABIT) is a therapeutic approach designed to improve the motor skills and functional use of both arms in individuals with conditions such as cerebral palsy. The core principle of HABIT is to encourage voluntary exercise by actively engaging the affected side, which may be weaker or partially paralyzed, in various activities. This approach aims to reduce physical and mental discomfort while maximizing the effectiveness of the training.
Study: NCT06657638

Intervention type: DIAGNOSTIC_TEST
Intervention: Thoracentesis
Description: Aspiration of pleural effusion
Study: NCT06659250

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-06414300
Description: Participants will receive oral ascending doses.
Study: NCT06387095

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 1. no block
Description: After extubation, patient-controlled analgesia will be applied for 24 hours (with PCA infusion pump device). During the follow-up of the patients in intensive care, extubation times, additional analgesic needs, pain scores; intensive care and hospital discharge times will be recorded.
Study: NCT06659250

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive matching placebo.
Study: NCT06661356

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COMPrEP
Description: Participants will be paired with peer lay workers and will meet with peer lay workers at private community location. They will discuss options for oral PrEP with peer lay workers and be provided provide daily oral PrEP or event-driven (2-1-1) PrEP. Participants will take part in rapid HIV testing at each visit. They will also meet with peer lay workers at private community location for follow-up at 1,3,6,9, and 12 months
Study: NCT06387095

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 2. superficial parasternal block
Description: After induction, the patient will undergo an ultrasound-guided superficial parasternal plan block. . After extubation, patient-controlled analgesia will be applied for 24 hours (with PCA infusion pump device). During the follow-up of the patients in intensive care, extubation times, additional analgesic needs, pain scores; intensive care and hospital discharge times will be recorded.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 3. deep parasternal block
Description: After induction, the patient will undergo an ultrasound-guided deep parasternal plane block. . After extubation, patient-controlled analgesia will be applied for 24 hours (with PCA infusion pump device). During the follow-up of the patients in intensive care, extubation times, additional analgesic needs, pain scores; intensive care and hospital discharge times will be recorded.
Study: NCT05533684

Intervention type: DRUG
Group type: OTHER
Intervention: Gabapentin
Description: single preoperative dose of 600 mg gabapentin
Study: NCT06347835

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: symbiotic
Description: The intervention is made up of multiple probiotics and prebiotics (20g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: whey protein
Description: The intervention is made up of whey protein supplements (20g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: whey protein
Description: The intervention is made up of whey protein supplements (20g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: symbiotic placebo
Description: The intervention is made up of maltodextrin (20g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: symbiotic placebo
Description: The intervention is made up of maltodextrin (20g/d) and dietary pattern modification.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: whey protein placebo
Description: The intervention is made up of maltodextrin (20g/d) and dietary pattern modification.