Study: NCT06645470

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Medical Care (SMC)
Description: Standard Medical Care will continue to receive their regular standard clinical care during the 6-month intervention period of this study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Medical Care (SMC)
Description: Standard Medical Care will continue to receive their regular standard clinical care during the 6-month intervention period of this study.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Medical Care (SMC)
Description: Standard Medical Care will continue to receive their regular standard clinical care during the 6-month intervention period of this study.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Monitoring Contacts
Description: Participants will receive contacts with the research staff at weeks 6, 12, and 18.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Monitoring Contacts
Description: Participants will receive contacts with the research staff at weeks 6, 12, and 18.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Monitoring Contacts
Description: Participants will receive contacts with the research staff at weeks 6, 12, and 18.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic Training
Description: Aerobic Training will be supervised exercise. It will occur on 3 days per week and will progress to 50 minutes per session (150 minutes per week). The intensity of the exercise will progress from 60%±5% to 70%±5% of age-predicted maximal heart rate (if taking beta-blocker medication intensity will progress from a Rating of Perceived Exertion of 11-13 to 12-14 based on the 6-20 Borg scale). While walking will be the preferred mode of exercise, alternative forms of cardiovascular exercise (upright cycling, elliptical, etc.) are allowed to accommodate any physical limitations that may be present for a participant. Heart rate will be monitored throughout these exercise sessions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance Training
Description: Resistance Training will be supervised exercise. It will occur 3 days per week and includes 8 exercises performed in a prespecified order. Week 1-2 sessions focus on familiarization to acclimate the participant to the equipment, proper form, to establish initial weight (load) for training, and with performing multiple sets per day. For Weeks 3-8, participants will engage in 2 sets per exercise with the weight adjusted to elicit muscle fatigue in 8-12 repetitions per set. This progresses to 3 sets per exercise from Week 9 until the end of the intervention period. When 12 repetitions for a specific exercise can be achieved, the resistance will increase for that exercise at the next session. There is a 90 second rest period between each set of an exercise. Heart rate will be monitored throughout these exercise sessions.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Nutrition Education
Description: A single counseling session to discuss the dietary recommendations when taking an obesity medication.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutrition Education
Description: A single counseling session to discuss the dietary recommendations when taking an obesity medication.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutrition Education
Description: A single counseling session to discuss the dietary recommendations when taking an obesity medication.