TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06420323

Intervention type: DEVICE
Intervention: Treatment with NovoX® Cup
Description: NovoX® Cup treatment

Intervention type: DEVICE
Intervention: Treatment with Omnistrip®
Description: Omnistrip® treatment
Study: NCT06463886

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STEP-AD
Description: This in-person STEP-AD intervention will consist of 10 sessions. Session 1: Life Steps Adherence Session 2: Psychoeducation on the treatment model Session 3: Substance Use and Enhancing Resilience Session 4: Trauma Impact Session 5: Cognitive Restructuring Session 6: Racial Discrimination Impact and Coping Session 7: HIV Stigma Impact and Coping Session 8: Gender-related Stressors and Coping Session 9: Body Image and Healthy Relationships Session 10: Practice, Review, and Relapse Prevention. Each session lasts for about 40 to 60 minutes.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced treatment as usual (E-TAU)
Description: Participants assigned to the E-TAU condition will receive 10 in person sessions to ensure comparable contact time with study staff and identical incentives. The first session will consist of a session on healthy living with HIV (CDC content on HIV 101 \[highlights importance of engaging in care, adhering to medication, finding support\], nutrition, and physical activity. The remaining 9 sessions will consist of neutral (daily events) writing. Women will be asked to write a description of their plans for the next 24 hours.
Study: NCT06348823

Intervention type: DIAGNOSTIC_TEST
Intervention: volume survey
Description: All subjects received oral hygiene instructions and, if needed, a dental cleaning of plaque and calculus. After calibration using digital photographs, intraoral scans, and CBCT, one dentist, who was not involved in the screening phase to avoid any bias, obtained all clinical parameters (gingival biotype, probing depth, gingival thickness, gingival width). Two test subjects were examined prior starting with enrollment and data collection.

Intervention type: DIAGNOSTIC_TEST
Intervention: volume survey
Description: All subjects received oral hygiene instructions and, if needed, a dental cleaning of plaque and calculus. After calibration using digital photographs, intraoral scans, and CBCT, one dentist, who was not involved in the screening phase to avoid any bias, obtained all clinical parameters (gingival biotype, probing depth, gingival thickness, gingival width). Two test subjects were examined prior starting with enrollment and data collection.
Study: NCT06652009

Intervention type: OTHER
Intervention: Radical nephroureterectomy
Description: Radical nephroureterectomy

Intervention type: RADIATION
Intervention: Radical radiotherapy
Description: Radical radiotherapy with stereotactic body radiation therapy (SBRT) or moderately segmented radiotherapy
Study: NCT06653790

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychosocial stimulations
Description: The psychosocial stimulation will be offered in two phases: in-patient (at stabilization unit) and after discharge patient will be referred to out-patient (at outpatient therapeutic centre) and developmental out-patient. The sessions with development paediatrician and team will be held every week lasting for about 20-40 min in the presence of the caregiver. The intervention includes auditory, tactile and visual stimulation, hand-eye coordination, and different types of sensory-motor training that included fine and gross motor activities. The guiding principle will be to enhance a child's holistic development-cognitive, language, physical, and social-in an integrated manner by using age-appropriate play materials, cultural tools, and resources.
Study: NCT05634629

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anterior Lamellar Recession
Description: ALR is a common surgical treatment that splits the skin and orbicularis oculi muscle from the tarsus and conjunctiva to recede the anterior lamella and expose the tarsus. Interlamellar separation can be accomplished via a grey line technique, an eyelid crease approach, or a combination of the two

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bilamellar Tarsal Rotation
Description: the full-thickness transverse blepharotomy combined with everting sutures to rotate the inferior portion of the upper lid outwards and this procedure has a low recurrence risk
Study: NCT06024746

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Finerenone
Description: Oral finerenone.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin
Description: Oral empagliflozin.
Study: NCT06398704

Intervention type: OTHER
Intervention: Standart of care
Description: No additional intervention was made. An evaluation was made.

Intervention type: OTHER
Intervention: Standart of care
Description: No additional intervention was made. An evaluation was made.

Intervention type: OTHER
Intervention: Standart of care
Description: No additional intervention was made. An evaluation was made.
Study: NCT05707858

Intervention type: OTHER
Intervention: Development of the NAPFA score
Description: In subjects with suspected food allergy we will evaluate main anamnestic, and clinical features to develop the NAPFA score
Study: NCT06541093

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UVAX-1107
Description: Novel HIV-1 protein nanoparticles vaccine candidate (WT) mixed with Aluminum Hydroxide (AH) and CpG 1018 adjuvants

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UVAX-1107
Description: Novel HIV-1 protein nanoparticles vaccine candidate (WT) mixed with Aluminum Hydroxide (AH) and CpG 1018 adjuvants

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UVAX-1107
Description: Novel HIV-1 protein nanoparticles vaccine candidate (WT) mixed with Aluminum Hydroxide (AH) and CpG 1018 adjuvants

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UVAX-1197
Description: Novel HIV-1 protein nanoparticles vaccine candidate (GT) mixed with Aluminum Hydroxide (AH) and CpG 1018 adjuvants

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UVAX-1197
Description: Novel HIV-1 protein nanoparticles vaccine candidate (GT) mixed with Aluminum Hydroxide (AH) and CpG 1018 adjuvants

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline injection
Study: NCT04631185

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Single pre-operative dose of intravenous antibiotics with intraoperative redosing
Description: Intravenous cefazolin, a cephalosporin antibiotic, will be prescribed to all patients before surgery. In case of allergy to cefazolin, intravenous clindamycin will be prescribed. For allergy to both antibiotics, an appropriate antibiotic should be chosen by the surgeon and documented. All patients will receive one dose of antibiotic within 60 minutes prior to incision, and any intraoperative doses of antibiotics according to current recommendations based on the antibiotic's dosing and on operative time.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single pre-operative dose of intravenous antibiotics with intraoperative redosing
Description: Intravenous cefazolin, a cephalosporin antibiotic, will be prescribed to all patients before surgery. In case of allergy to cefazolin, intravenous clindamycin will be prescribed. For allergy to both antibiotics, an appropriate antibiotic should be chosen by the surgeon and documented. All patients will receive one dose of antibiotic within 60 minutes prior to incision, and any intraoperative doses of antibiotics according to current recommendations based on the antibiotic's dosing and on operative time.
Study: NCT05695001

Intervention type: DEVICE
Intervention: Efferon CT
Description: Efferon CT is a cylindrical body made of polycarbonate, filled with spherical granules of polymer hemocompatible macroporous styrene-divinylbenzene copolymer of super cross-linked type and isotonic sodium chloride solution. The device is manufactured according to TU 32.50.50-001-12264678-2018, has passed the necessary tests and is registered in Russia as a medical product RZN 2019/8886.
Study: NCT05584501

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care Navigator
Description: The Dental Team will have a Care Navigator as an added resource to assist with offering, implementing, and counseling for HIV testing; providing PrEP education and linkage; and providing linkage and re-linkage to HIV care.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Health Information Supported Ending the HIV Epidemic (ETE) Activities in Dental Setting
Description: Dental Teams will receive a Best Practice Alert (BPA) when they have a patient who should be offered HIV testing. Dental Teams will also be notified when they have a patient known to be HIV positive but out of HIV care.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Health Information Supported Ending the HIV Epidemic (ETE) Activities in Dental Setting
Description: Dental Teams will receive a Best Practice Alert (BPA) when they have a patient who should be offered HIV testing. Dental Teams will also be notified when they have a patient known to be HIV positive but out of HIV care.
Study: NCT04631185

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: One week of post-operative antibiotics
Description: The patients will be prescribed one week of Cephalosporin Antibiotic (Keflex/Duricef/Other) of their surgeon's choice.
Study: NCT05138328

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Treatment of basal cell carcinoma with Nd:YAG laser under imaging guidance of optical coherence tomography (OCT)
Description: This will use optical coherence tomography (OCT) to assess the margins of basal cell carcinoma. Treatment will be completed by Nd:YAG laser.
Study: NCT05897216

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-383
Description: QD, PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-383
Description: QD, PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-501, D745, D150, D029
Description: QD, PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-501, D745, D150, D029
Description: QD, PO
Study: NCT05638607

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensified occupational therapy
Description: The intervention is an intensified occupational therapy effort, which does not take time away from other occupational therapy efforts.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Intensified occupational therapy
Description: The intervention is an intensified occupational therapy effort, which does not take time away from other occupational therapy efforts.
Study: NCT06521138

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational interviewing group
Description: The intervention group will receive motivational interviewing based on the transtheoretical model in addition to routine care. Motivational interviews are structured in line with the stages of change and behavioral change processes, which are the basic structures of the transtheoretical model. Three sessions of motivational interviewing with a session duration of 30 min will be implemented. Two sessions of motivational interviewing in the prenatal period and one session of motivational interviewing in the postnatal period.

Intervention type: OTHER
Group type: OTHER
Intervention: Control group
Description: Participants in the control group will receive routine care at the center.
Study: NCT06653088

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Education program
Description: A four-month intervention will be implemented, led by the PE teacher, with three sessions per week. These sessions will last 45 minutes each (Koolwikh et al., 2023), divided into 5 minutes of warm-up, 35 minutes of intervention content, and 5 minutes of return to calm.~The program content of the intervention group will contemplate a warm-up with several activities, such as dancing or games. The intervention part will be composed of circuit-based exercises with several stations and games involving locomotion skills, namely run, gallop, slide, skip, jump, hop, etc.; games that integrate manipulative skills, such as throwing, catching, kicking, punting, striking, rolling and bouncing/dribbling; balance games involving swinging, turning, pulling, etc. Games involving perceptual motor skills, such as body schema, laterality, temporality, and spatiality, and games focused on PA. The return to calm will include activities such as yoga, meditation, and flexibility.
Study: NCT06487832

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subcutaneous GLP1-RA
Description: Subcutaneous administration of semaglutide

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Subcutaneous placebo
Description: Subcutaneous administration of NaCl
Study: NCT06325462

Intervention type: DEVICE
Intervention: sensors of regional cerebral oxygen saturation (O3 regional oximeter, Masimo Corp, Irvine, CA) FDA Reg No. 3011353843
Description: O3 regional oximetry monitors the regional hemoglobin oxygen saturation of the blood (rSO2) in adult patients, placed on the forehead by noninvasive and continuous combining arterial and venous oxygen saturation signals from near-infrared spectroscopy (NIRS)

Intervention type: DEVICE
Intervention: sensors of regional cerebral oxygen saturation (O3 regional oximeter, Masimo Corp, Irvine, CA) FDA Reg No. 3011353843
Description: O3 regional oximetry monitors the regional hemoglobin oxygen saturation of the blood (rSO2) in adult patients, placed on the forehead by noninvasive and continuous combining arterial and venous oxygen saturation signals from near-infrared spectroscopy (NIRS)
Study: NCT05322317

Intervention type: OTHER
Group type: OTHER
Intervention: ADVANCE-PC training via ECHO
Description: To assess the feasibility of using a technology-based platform to deliver the ADVANCE-PC program to multiple primary care clinics. This model will be based on the ECHO program, a tele-mentoring program which uses communications technology to provide facilitated education, case review, and peer-to-peer problem solving remotely. Our working hypothesis is that the use of ECHO will be efficient (allowing several clinicians and teams to be supported simultaneously while creating a community of practice), feasible (that clinicians will enroll and share experiences via mentoring, guidance, feedback, and didactic education), and have the potential to impact patients as clinicians perceptions shift to favor ACP, their skills increase, and they are able to integrate ACP for patients with dementia into their clinic.
Study: NCT06377735

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: BAI-BACE
Description: Bronchial arterial infusion, bronchial arterial chemoembolization (BACE-BAI) procedure was performed as follows: Bronchial arteriography was performed to find tumor-feeding artery. After the catheter had been inserted into the tumor-feeding artery, paclitaxel (300 mg) was infused slowly at least 30 min. BAI (bronchial arterial infusion) chemotherapy was followed by BACE (Drug-eluting beads bronchial arterial chemoembolization); the CalliSpheres loaded with cis-platinum (30 mg) were infused into the tumor-feeding arteries until stasis or near-stasis of blood flow in the vessel was observed.
Study: NCT06123039

Intervention type: DIAGNOSTIC_TEST
Intervention: Tidal Volume Challenge
Description: The tidal volume challenge is a fluid response test that consists of increasing the tidal volume from 6 ml/kg to 8 ml/kg for 1 minute and evaluating PPV. If PPV increases by more than 2%, it is considered positive, otherwise it will be negative.

Intervention type: DIAGNOSTIC_TEST
Intervention: Tidal Volume Challenge
Description: The tidal volume challenge is a fluid response test that consists of increasing the tidal volume from 6 ml/kg to 8 ml/kg for 1 minute and evaluating PPV. If PPV increases by more than 2%, it is considered positive, otherwise it will be negative.

Intervention type: PROCEDURE
Intervention: Recruitment maneuver obtaining individualised PEEP
Description: The alveolar recruitment maneuver is a well-studied procedure to open the lung during invasive mechanical ventilation, allowing us to achieve the best PEEP for that lung, which is individualised PEEP.

Intervention type: PROCEDURE
Intervention: Recruitment maneuver obtaining individualised PEEP
Description: The alveolar recruitment maneuver is a well-studied procedure to open the lung during invasive mechanical ventilation, allowing us to achieve the best PEEP for that lung, which is individualised PEEP.
Study: NCT05976334

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] Subasumstat
Description: \[14C\] Subasumstat IV infusion.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Subasumstat
Description: Subasumstat IV infusion.
Study: NCT05280574

Intervention type: DEVICE
Intervention: GE Portrait Monitor
Description: All patients will be monitored

Intervention type: DEVICE
Intervention: GE Portrait Monitor
Description: All patients will be monitored

Intervention type: DEVICE
Intervention: GE Portrait Monitoring with intervened by clinician
Description: Monitoring might be intervened if clinician believe that the alarm is clinically meaningful

Intervention type: DEVICE
Intervention: GE Portrait Monitoring randomized to blinded or unblinded
Description: Without intervention
Study: NCT06294314

Intervention type: PROCEDURE
Intervention: Fertilized ACL
Description: Fertilized ACL is an acl reconstruction with Bone marrow aspirate, demineralized bone matrix, and an internal brace.
Study: NCT06295133

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stress
Description: The stress management intervention will consist of three individual sessions, each lasting one hour, with approximately 15 days between each session. The sessions will be scheduled as follow: week 5 and 6 (session 1), week 7 and 8 (session 2), week 9, 10, and 11 (session 3). During these sessions, subjective and objective indicators of stress will be recorded to assess the progress of each student.
Study: NCT05272267

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: AI-assisted models providing diagnosis and prognostic information
Description: AI-assisted models providing diagnosis and prognostic information in the ED, including triage, ICD coding, chest x ray alerts, critical event alerts, readmission prediction, and post-cardiac arrest prognostication.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Critical treatment
Description: Critical treatment of the emergency room
Study: NCT05410769

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Compassion Focused Therapy
Description: This pilot study aims to propose for the first time a Compassion protocol (Compassion Program for Parkinson) to a group of patients with PD and a group of caregivers and to evaluate its feasibility and effectiveness. The investigators aim to assess whether the program is effective in improving the quality of life and psychiatric symptoms of the patients and caregivers. The Compassion program is a healthy form of self- acceptance, which involves being touched by one's own suffering, along with the desire to alleviate it and treat oneself with understanding and kindness. The duration of the protocol will be 6 weeks (1 meeting/ week of 2 hours). The investigators will recruit 40 patients and 20 caregivers who will be assessed pre and post intervention (Compassionate Mind Training) with interviews, self reports and measurement of the heart rate variability.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Compassion Focused Therapy
Description: This pilot study aims to propose for the first time a Compassion protocol (Compassion Program for Parkinson) to a group of patients with PD and a group of caregivers and to evaluate its feasibility and effectiveness. The investigators aim to assess whether the program is effective in improving the quality of life and psychiatric symptoms of the patients and caregivers. The Compassion program is a healthy form of self- acceptance, which involves being touched by one's own suffering, along with the desire to alleviate it and treat oneself with understanding and kindness. The duration of the protocol will be 6 weeks (1 meeting/ week of 2 hours). The investigators will recruit 40 patients and 20 caregivers who will be assessed pre and post intervention (Compassionate Mind Training) with interviews, self reports and measurement of the heart rate variability.
Study: NCT05589649

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: Ultrasound-guided erector spinae plane block

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Paravertebral block
Description: Ultrasound-guided paravertebral block
Study: NCT04881448

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: collection of serum/capillary creatinine values
Description: collection of serum/capillary creatinine values
Study: NCT06573112

Intervention type: DIAGNOSTIC_TEST
Intervention: ultrasound assessment for catheter-related thrombosis.
Description: Patients with newly inserted central venous catheter will be assessed with vascular ultrasound for the presence of catheter-related thrombosis
Study: NCT05821010

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Lyophilized fecal microbiota transplantation capsules
Description: Oral administration (capsule)

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsules
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: A. soehngenii
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: A. soehngenii
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pasteurized A. muciniphila
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Pasteurized A. muciniphila
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: B. animalis subsp. lactis
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: B. animalis subsp. lactis
Description: Oral administration (capsule)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fructo-oligosaccharides
Description: Oral administration (dissolved in water)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Fructo-oligosaccharides
Description: Oral administration (dissolved in water)
Study: NCT06573320

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical exercise
Description: physical exercise
Study: NCT06572735

Intervention type: OTHER
Intervention: QoL surveys
Description: 2 quality of life surveys (OV28 and ELD14) will be completed by patients every 3 months during a 12-month period

Intervention type: OTHER
Intervention: Geriatric assessment (G-CODE)
Description: A geriatric assessment (G-CODE) will be performed by the research staff every 3 months during a 12-month period

Intervention type: BIOLOGICAL
Intervention: Blood sampling
Description: A supplementary volume of blood will be collected from a routine blood sample (8 mL) at 3 different time points : one at inclusion, one 6 and 12 months after the beginning of PARP inhibitors treatment. Genetic lab test will be performed to assess whether there is a specific genetic signature for PARP inhibitors toxicity.