TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06481514

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Interpretation of the CTG using FRI score
Description: At each of the components of the score will be assigned a score of 1 if the variable evaluated is considered normal, 0 if classified as abnormal. To encourage a simplified clinical interpretation of the different scores obtained (score from 1 to 8) they will be classified into 3 risk categories: Score 5-8: green zone, Score 3-4: zone yellow, Score 1-2: red zone. An FRI of 1-2 (red zone) is to be considered as anomalous

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Classic interpretation of the CTG
Description: evaluate the CTG of group B patients according to the usual internal management protocols
Study: NCT06409884

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: T-cell activation test using intracellular markers
Description: A blood sample will be taken which is needed for the T-cell activation test (TAT). The TAT will than be performed by trained laboratory personnel.
Study: NCT04946292

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Theory-derived intervention
Description: The intervention will be delivered through multimedia materials and group activities, as appropriate. Participants will spend approximately 30-45 minutes for the intervention. Intervention materials and activities will be carefully designed to address all the constructs/ domains of the selected theoretical model(s). The effectiveness of the interventions will be evaluated using behavioural outcomes (diet, brushing, flossing) and clinical outcomes (oral hygiene, caries and periodontal conditions).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional health education
Description: The conventional health education will be delivered through an oral health talk and oral health booklet. Topics covered are: (i) common oral diseases and its consequences; (ii) common dental problems among older adults; (iii) importance of oral health measures (healthy diet, toothbrushing and dental flossing); and (iv) proper techniques for toothbrushing and dental flossing.
Study: NCT05593614

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A 100 mL bottle of hydrogel formulation containing no active substance
Study: NCT06067503

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-fluorofuranylnorprogesterone
Description: The dose of the investigational imaging agent, FFNP, is approximately 7 millicurie (mCi) (259 megabecquerels (MBq)), IV slow infusion over approximately two minutes followed by saline flush.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Liquid Biopsy
Description: 20ml of whole blood will be collected into two Ethylenediaminetetraacetic acid (EDTA) tubes at each timepoint, CTCs are isolated using the microfluidic Versatile Exclusion-based Rare Sample Analysis (VERSA) platform that integrates CTC capture with RNA extraction on a single chip using Exclusion-Based Sample Preparation (ESP) technology

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography/Computed Tomography
Description: FFNP drug in combination with PET/CT scans to image participant
Study: NCT06321965

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evaluation of body composition and metabolism
Description: Food survey : The dietary survey questionnaire will be sent to parents at D0 and M18. Parents will be asked to complete it for 3 days before the M6 and M24.~Bioelectrical impedancemetry: Evaluated at M6 and M24. Renal ultrasound: Evaluated at M6, is a non-invasive examination that analyzes the appearance of the kidney and urinary tract.~Dual-energy X-ray absorptiometry (DXA) : Evaluated at M6, it measures body composition using spectral imaging, including fat mass, lean mass and bone mineral density.~Fibroscan : Evaluated at M6 and M24. This examination uses pulse elastography to measure liver elasticity, which provides information on the presence of hepatic fibrosis, and sound attenuation, which provides information on the presence of liver fat overload.~Indirect calorimetry : Evaluated at M6. This device enables precise measurement of Resting Energy Expenditure , Respiratory Quotient and metabolic substrate oxidation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: SMAIS : The questionnaire has been developed specifically for ASI. At D0, M6, M12, M18 and M24.~HUI2 : specializes in preference-based measures of health-related quality of life. At D0, M6, M12, M18 and M24.~Peds QL : is a modular instrument designed to measure health-related quality of life and disease-specific symptoms. At D0, M6, M12, M18 and M24.~Neuromuscular module : 17 disease-related items. It is evaluated at D0, M6, M12, M18 and M24.~Family impact module : It measures parents' reported physical, emotional, social and cognitive functioning, communication and concerns. At D0, M12, and M24.~ASI cost questionnaire: At visit 1 (D0): This questionnaire, completed by the parents, includes information on occupation, parents' working hours and any reduction in them due to the child's pathology, the number of working days missed by the parents or school days missed by the child, and disability-related costs.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biocollection
Description: A blood bio collection (optional) will be offered to patients at D0, M6 , M12, M18, M24.~Patients receiving intrathecal injections will also be offered the opportunity to participate in a CSF (cerebrospinal fluid) biocollection (optional).

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Skinfold measurement
Description: The tricipital point should be marked on the posterior aspect of the arm, on the midline of the tricipital muscle, midway between the acromion and the radius. At D0, M6, M12, M18 and M24
Study: NCT05899309

Intervention type: DIAGNOSTIC_TEST
Intervention: liver and spleen stiffness test and laboratory test
Description: Diagnosis of cirrhosis can be based on liver biopsy,radiological ,clinical or liver stiffness measurement (LMS)

Intervention type: DIAGNOSTIC_TEST
Intervention: liver and spleen stiffness test and laboratory test
Description: Diagnosis of cirrhosis can be based on liver biopsy,radiological ,clinical or liver stiffness measurement (LMS)
Study: NCT05114785

Intervention type: DIAGNOSTIC_TEST
Intervention: Multi Parametric Cardiac Magnetic Resonance
Description: Research based Cardiac MRI evaluation to determine cardiovascular haemodynamics

Intervention type: DIAGNOSTIC_TEST
Intervention: Multi Parametric Cardiac Magnetic Resonance
Description: Research based Cardiac MRI evaluation to determine cardiovascular haemodynamics
Study: NCT04890223

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief MI intervention
Description: Brief MI intervention

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo intervention
Description: Generic health advice consultations and self-help smoking cessation booklets
Study: NCT05941923

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: respiratory critical care support
Description: Patients in the intervention group will be received respiratory critical care support
Study: NCT05863910

Intervention type: DRUG
Intervention: Medical Cannabis
Description: Any cannabis product that is available to participants through the Medical Cannabis Access Program is eligible to be included in this study.

Intervention type: DRUG
Intervention: Medical Cannabis
Description: Any cannabis product that is available to participants through the Medical Cannabis Access Program is eligible to be included in this study.
Study: NCT06160193

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief behavioral parent training with optional care as usual
Description: A brief behavioral parent training program that combines individually-tailored stimulus control and contingency management techniques to treat children's behavioral difficulties in two (bi)weekly training sessions of 120 minutes, and a third session of 60 minutes, in which the training will be evaluated and maintenance training will be provided.
Study: NCT05863910

Intervention type: DRUG
Intervention: Medical Cannabis
Description: Any cannabis product that is available to participants through the Medical Cannabis Access Program is eligible to be included in this study.
Study: NCT06160193

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Care as usual
Description: Care as usual may include all mental health care that is usually provided within or outside (e.g., at a child mental healthcare institution or at school) the general practitioners practice, except from pharmacological treatment for children's behavioral difficulties and/or behavioral parent training/support, up until the first posttreatment assessment (T1). Care as usual can also imply that there is no support or treatment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care as usual
Description: Care as usual may include all mental health care that is usually provided within or outside (e.g., at a child mental healthcare institution or at school) the general practitioners practice, except from pharmacological treatment for children's behavioral difficulties and/or behavioral parent training/support, up until the first posttreatment assessment (T1). Care as usual can also imply that there is no support or treatment.
Study: NCT06453850

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of FLEXIGO delivery catheter
Description: Use of FLEXIGO delivery catheter for implantation of ventricular pacing lead
Study: NCT05446584

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Definition Transcranial Direct Current Stimulation
Description: HD-tDCS for this study is not intended to be a treatment, and will be applied continuously for 30 minutes at sham (0 mA) or 2 mA for active conditions across 3 consecutive daily sessions to probe neural circuit integrity. This specific HD-tDCS device is completely computer driven, running on a laptop using specialized software. Circular electrodes (12-mm in diameter) filled with conductive gel will be placed in a 4x1 ring configuration with the central electrode being the anode surrounded by four cathodes.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Definition Transcranial Direct Current Stimulation
Description: HD-tDCS for this study is not intended to be a treatment, and will be applied continuously for 30 minutes at sham (0 mA) or 2 mA for active conditions across 3 consecutive daily sessions to probe neural circuit integrity. This specific HD-tDCS device is completely computer driven, running on a laptop using specialized software. Circular electrodes (12-mm in diameter) filled with conductive gel will be placed in a 4x1 ring configuration with the central electrode being the anode surrounded by four cathodes.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: High Definition Transcranial Direct Current Stimulation
Description: HD-tDCS for this study is not intended to be a treatment, and will be applied continuously for 30 minutes at sham (0 mA) or 2 mA for active conditions across 3 consecutive daily sessions to probe neural circuit integrity. This specific HD-tDCS device is completely computer driven, running on a laptop using specialized software. Circular electrodes (12-mm in diameter) filled with conductive gel will be placed in a 4x1 ring configuration with the central electrode being the anode surrounded by four cathodes.
Study: NCT04751071

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Roflumilast 500Mcg Tab
Description: Roflumilast 500µg tablet once daily for 6 weeks plus the standard therapy
Study: NCT05544331

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise group (written form)
Description: The exercise program will be structUred with core stabilization exercises. Patients will be given the written form of exercises and will be applied as home exercises. Exercise progression will be provided by position changes.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise group (video based)
Description: The exercise program will be structUred with core stabilization exercises. Patients will be given the exercise videos, which provide visual and auditory feedback, and will be applied as home exercises. Exercise progression will be provided by position changes.
Study: NCT04751071

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet once daily for 6 weeks plus the standard therapy
Study: NCT05622435

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: T10070, Plastic tube with a roll-on applicator filled with an ointment
Description: 6 times per day on both (upper and lower) eyelids of right eye during 7 to 9 days.
Study: NCT06196398

Intervention type: DRUG
Intervention: Standard Medical Treatment on the basis of anti-platelet therapy
Description: 1. Anti-platelet therapy: aspirin 75mg+clopidogrel 100mg will be applied for patients with severe ICAS stenosis (70%-90%) suffering stroke or TIA within 30 days. After 90 days, single anti-platelet therapy will be continued.~2. Intensive statin therapy: Statins with high doses~3. Blood pressure: below 140/90mmHg~4. LDL: less than 1.81mmol/L(70mg/dl)~5. Fasting blood glucose controlled to 5.9mmol/L, and glycosylated hemoglobin A1c reduced to less than 7%~6. Cigarette and alcohol quitting~7. Oral anticoagulants for atrial fibrillation

Intervention type: DRUG
Intervention: Standard Medical Treatment on the basis of anti-platelet therapy
Description: 1. Anti-platelet therapy: aspirin 75mg+clopidogrel 100mg will be applied for patients with severe ICAS stenosis (70%-90%) suffering stroke or TIA within 30 days. After 90 days, single anti-platelet therapy will be continued.~2. Intensive statin therapy: Statins with high doses~3. Blood pressure: below 140/90mmHg~4. LDL: less than 1.81mmol/L(70mg/dl)~5. Fasting blood glucose controlled to 5.9mmol/L, and glycosylated hemoglobin A1c reduced to less than 7%~6. Cigarette and alcohol quitting~7. Oral anticoagulants for atrial fibrillation
Study: NCT06519383

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: guided implant surgery
Description: Surgical guide is fabricated and fitted onto the patient's arch and implant is placed with guide in place.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: guided implant surgery
Description: Surgical guide is fabricated and fitted onto the patient's arch and implant is placed with guide in place.
Study: NCT04764734

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NightOwl
Description: The NightOwl is a finger-mounted home sleep apnea testing device
Study: NCT06516263

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Leukocyte and platelet rich fibrin
Description: Formation of an Leukocyte and platelet rich fibrin clot and placement into the osteotomy site prior to implant placement

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Standard implant placement
Description: Standard implant placement without Leukocyte and platelet rich fibrin
Study: NCT05107973

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baduajin
Description: The intervention will consist in a 1 hour supervised Baduajin sessions conducted once a week a certified instructor with more than 10 years of experience. Each session will start with 5 min of warm up, 50 minutes of Baduajin and 5 min of cool down. In the main part the participants exercise the wholes set of Baduajin that consist of eigth forms.
Study: NCT05128006

Intervention type: OTHER
Intervention: New patient teledermatology visit
Description: new patient teledermatology visits
Study: NCT04932213

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tropicamide Ophthalmic
Description: Tropicamide eye drops are used for dilating pupils (mydriasis) to do comprehensive fundus examination.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tropicamide Ophthalmic
Description: Tropicamide eye drops are used for dilating pupils (mydriasis) to do comprehensive fundus examination.
Study: NCT05586958

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tigulixostat
Description: Xanthine Oxidase Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tigulixostat
Description: Xanthine Oxidase Inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tigulixostat
Description: Xanthine Oxidase Inhibitor

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo
Study: NCT04965922

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Multimodal intervention
Description: The intervention consists of identifying the individual needs of each caregiver and patient and identifying sources of improvement in the management of daily life, including the optimization of social support. This optimization requires the involvement of people in the environment (family, friends, neighbours) who can provide help, support of any kind, recurrent or punctual, minimizing negative family interactions and maximizing positive contributions by each in supporting and supporting the individual.~The intervention is personalized in the sense that the content of each session seeks to adapt itself to the specificities of the couple situation and its surroundings.~interviews/meetings involving a psychologist social worker.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimodal intervention
Description: The intervention consists of identifying the individual needs of each caregiver and patient and identifying sources of improvement in the management of daily life, including the optimization of social support. This optimization requires the involvement of people in the environment (family, friends, neighbours) who can provide help, support of any kind, recurrent or punctual, minimizing negative family interactions and maximizing positive contributions by each in supporting and supporting the individual.~The intervention is personalized in the sense that the content of each session seeks to adapt itself to the specificities of the couple situation and its surroundings.~interviews/meetings involving a psychologist social worker.
Study: NCT04327635

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PEP
Description: A biological drug made of certain parts of blood from living blood donors obtained from a certified blood bank. At the time of cardiac catheterization patients will undergo one-time intracoronary infusion of 10 milliliters of PEP dosage consisting of approximately 5%, 10%, or 20% PEP. PEP dose will be infused immediately distal to the newly placed stent over approximately 5 minutes.
Study: NCT05476432

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: HAIC
Description: The microcatheter was advanced into the hepatic artery, and patients were transferred to the inpatient ward for drug infusion via the hepatic artery

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HAIC
Description: The microcatheter was advanced into the hepatic artery, and patients were transferred to the inpatient ward for drug infusion via the hepatic artery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FOLFOX 2d
Description: Oxaliplatin, leucovorin, bolus fluorouracil, and infusional fluorouracil 2400 mg/m² over 46 hours

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOLFOX 1d
Description: Oxaliplatin, leucovorin, bolus fluorouracil, and infusional fluorouracil 2400 mg/m² over 23 hours
Study: NCT05650138

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Jacobson's progressive muscular relaxation technique
Description: subjects will receive Jacobsons muscle relaxation technique. Patients will be demonstrated with the technique to contract and relax various groups of muscles, to coordinate contractions and relaxations with deep breaths and to perform the entire procedure with eyes closed in supine lying down position. Every subject will perform this supervised relaxation for 6 repetitions during a single session on once a day basis for four weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 30 min walk
Description: 30 minutes walk twice a week for 4 weeks

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 30 min walk
Description: 30 minutes walk twice a week for 4 weeks
Study: NCT04956055

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reflexology
Description: The patient will be kept in a lying position. First, the patient will be given four minutes of hand reflexology on each hand with warming and stimulation techniques.Reflexology will be applied to the left hand with the thumb of the right hand, the thumb of the left hand and the special points in the right hand. It will be applied to the fingers, palm, back of the hand, and finally the wrists, respectively, starting with the fingertips and using special reflexology techniques (a total of six minutes for each hand separately). By sending a moderate stimulus, a total of 20 minutes of reflexology session will continue.Since the patient reveals and uses his own internal energy at the end of the session, nobody should talk to the patient until five minutes after the procedure. Survey questions and vital signs would be examined five minutes after the session and the research with the participant would end.
Study: NCT06054854

Intervention type: BIOLOGICAL
Intervention: Extra blood sampling, Non-invasive or leftover samples or medical waste
Description: Extra blood sampling, Urine, Saliva, Stool, Superficial nasal swamp sampling. Bronchoalveolar lavage fluid, Mediastinal node or mass, Peripheral nodule aspiration supernatant, Pleural fluid, Cerebrospinal fluid collection (leftover samples or medical waste).~Blood will be collected in larger quantity during a blood test planned as part of the patient's care.~Non-invasive or leftover samples or medical waste will be collected on top of the usual diagnosis and during follow-up, depending on the case.
Study: NCT06256354

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Routine thermal management
Description: Patients assigned to routine thermal management will not be pre-warmed and ambient intraoperative temperature will be maintained near 20°C per routine. Only transfused blood will be warmed. An upper- or lower-body forced-air cover will be positioned over an appropriate non-operative site but will not initially be activated. Should core temperature decrease to 35.5°C, the warmer will be activated as necessary to prevent core temperature from decreasing further. The target nasopharyngeal temperature is 35.5°C.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Target temperature management
Description: Pre-warming is performed with a full-body forced-air cover and electrically heated blanket for about 30 minutes before induction of anesthesia. The warmer will initially be set to high which corresponds to about 43°C. It will be subsequently adjusted to make patients feel warm, but not uncomfortably so. Patients will be warmed during surgery using two forced-air covers or combining forced-air covers with electric heating blanket when clinically practical. All intravenous fluids will be warmed to body temperature. There is no need to control ambient temperature since ambient temperature has little effect on core temperature in patients warmed with forced air. The target nasopharyngeal temperature is 36.8℃.