TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05160753

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic gastric function preserving surgery combined with resection of the anterior lymphatic drainage area
Description: A 4mL volume of double tracer is injected into the submucosa of the four quadrants of the primary tumor by intraoperative gastroscopic method., and 15 minutes after gastroscopic tracer injection, the green anterior lymph nodes were carefully dissected and removed from the surgical area and evaluated for lymph node metastasis by parallel intraoperative freezing.If all collected anterior lymph nodes are negative, laparoscopic gastric function preserving surgery will be performed.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic gastric function preserving surgery combined with resection of the anterior lymphatic drainage area
Description: A 4mL volume of double tracer is injected into the submucosa of the four quadrants of the primary tumor by intraoperative gastroscopic method., and 15 minutes after gastroscopic tracer injection, the green anterior lymph nodes were carefully dissected and removed from the surgical area and evaluated for lymph node metastasis by parallel intraoperative freezing.If all collected anterior lymph nodes are negative, laparoscopic gastric function preserving surgery will be performed.
Study: NCT05286710

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: pharmacomechanical thrombectomy (PMT)
Description: After randomization patients will be allocated to pharmacomechanical thrombectomy (PMT) via ipsilateral popliteal venous approach or to PMT via distal calf venous approach, bail-out contralateral femoral access can be used if puncture was failed in calf vein. After PMT treatment, residual thrombus was reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) was conducted if there was residual thrombus. Stenosis of iliac vein was assessed by multiangle venography and intravascular ultrasound (IVUS) was used if necessary. Percutaneous balloon angioplasty (PTA) was conducted if there was \>50% stenosis of the diameter of the iliac vein. A stent was placed if the residual stenosis was \>50% after PTA treatment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: pharmacomechanical thrombectomy (PMT)
Description: After randomization patients will be allocated to pharmacomechanical thrombectomy (PMT) via ipsilateral popliteal venous approach or to PMT via distal calf venous approach, bail-out contralateral femoral access can be used if puncture was failed in calf vein. After PMT treatment, residual thrombus was reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) was conducted if there was residual thrombus. Stenosis of iliac vein was assessed by multiangle venography and intravascular ultrasound (IVUS) was used if necessary. Percutaneous balloon angioplasty (PTA) was conducted if there was \>50% stenosis of the diameter of the iliac vein. A stent was placed if the residual stenosis was \>50% after PTA treatment.
Study: NCT05241717

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-based Management of Adolescent Pain (WebMAP)
Description: Participants will be asked to complete one module per week, which are approximately 20 minutes in length. Survivors and parents will be asked to spend approximately 4.5 hours each over the course of the intervention on WebMAP including 4 hours to complete the modules and 30 minutes total corresponding with a coach. Each week, patients log into WebMAP to learn a new skill and practice that skill for 1 week to allow time for skills acquisition. WebMAP consists of two separate, password-protected programs including one for adolescents and one for parents (http://webmap2.com).
Study: NCT05522894

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: 10mg/kg IV every 3 weeks (Q3W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: 10mg/kg IV every 3 weeks (Q3W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: 75mg/m2 IV every 3 weeks (Q3W)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: 175mg/m2 IV every 3 weeks (Q3W)
Study: NCT06362109

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine rehabilitation
Description: Routine rehabilitation consists of:~1. Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~2. Swallowing training, including lemon ice stimulation, empty swallowing training, and pronunciation training.~3. Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine rehabilitation
Description: Routine rehabilitation consists of:~1. Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~2. Swallowing training, including lemon ice stimulation, empty swallowing training, and pronunciation training.~3. Pulmonary function training, including standing training, cough training, and diaphragm muscle training.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-esophageal Tube Feeding
Description: The group is given enteral nutritional support with Intermittent Oro-esophageal Tube according to the following procedure: Before each feeding, inside and outside of the tube was cleaned with water. During feeding, the patient should maintain a semi-reclining or sitting position with mouth opened, and the tube was inserted slowly and smoothly into the upper part of the esophagus by medical staffs while the appropriate depth of intubation was checked with the calibration markings on the tube wall. The distance from the incisors to the head part of the tube should be between 22-25 cm.
Study: NCT04977154

Intervention type: OTHER
Intervention: Primary prevention
Description: The primary prevention that the trainers put in place for the hockey players
Study: NCT05719051

Intervention type: DRUG
Intervention: Albumin infusion
Description: Albumin infusion was administrated according to the standard clinical practice

Intervention type: DRUG
Intervention: Albumin infusion
Description: Albumin infusion was administrated according to the standard clinical practice

Intervention type: DRUG
Intervention: Albumin infusion
Description: Albumin infusion was administrated according to the standard clinical practice
Study: NCT06314529

Intervention type: OTHER
Intervention: Assessments
Description: Safety and efficacy assessments
Study: NCT06221059

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-1780 tablet；Henagliflozin Proline tablet；HRS-1780 tablet placebo ；Henagliflozin Proline tablet placebo
Description: Drug：HRS-1780 tablet Drug：Henagliflozin Proline tablet Drug：HRS-1780 tablet placebo Drug：Henagliflozin Proline tablet placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-1780 tablet；Henagliflozin Proline tablet；HRS-1780 tablet placebo ；Henagliflozin Proline tablet placebo
Description: Drug：HRS-1780 tablet Drug：Henagliflozin Proline tablet Drug：HRS-1780 tablet placebo Drug：Henagliflozin Proline tablet placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: HRS-1780 tablet；Henagliflozin Proline tablet；HRS-1780 tablet placebo ；Henagliflozin Proline tablet placebo
Description: Drug：HRS-1780 tablet Drug：Henagliflozin Proline tablet Drug：HRS-1780 tablet placebo Drug：Henagliflozin Proline tablet placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: HRS-1780 tablet；Henagliflozin Proline tablet；HRS-1780 tablet placebo ；Henagliflozin Proline tablet placebo
Description: Drug：HRS-1780 tablet Drug：Henagliflozin Proline tablet Drug：HRS-1780 tablet placebo Drug：Henagliflozin Proline tablet placebo
Study: NCT05753761

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behaviour- & Imaging-Guided Stepping Training Early Post-Stroke (BIG STEPS) intervention
Description: Using baseline accelerometry data, personalized goals of replacing sedentary time with stepping time will be developed.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behaviour- & Imaging-Guided Stepping Training Early Post-Stroke (BIG STEPS) intervention
Description: Using baseline accelerometry data, personalized goals of replacing sedentary time with stepping time will be developed.
Study: NCT04878614

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levothyroxine Tablet
Description: Standard clinical management

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levothyroxine Sodium
Description: Liquid levothyroxine through enteral feeding tube
Study: NCT05422430

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rebreathing-induced hypoxia
Description: Participants will rebreathe room air from a low-volume closed-circuit system for a period of 2 minutes.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Spontaneous breathing
Description: Participants will be spontaneously breathing during an oral glucose tolerance test.
Study: NCT04757038

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intradiscal injection
Description: The injection will be administered at V1 baseline (day 0). Any physical activity (e.g. jogging, tennis, weightlifting, prolonged upright position) in the 48 hours following the injection should be avoided.
Study: NCT06461481

Intervention type: DEVICE
Intervention: Withings Scanwatch
Description: Data captured by the used smartwatches (Withings Scanwatch) includes activity-related data (step count, minutes in certain intensity levels), basic cardiovascular measurements such as heart rate, and sleep-related data (total time asleep, sleep efficiency and quality etc.).
Study: NCT04921124

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Teriparatide
Description: PTH(1-34) cartridge and pen device
Study: NCT05036395

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The routine assessment protocol and AI-assisted cEEG Diagnostic tool
Description: The AI-assisted cEEG diagnostic tool is an automated seizure reporting system, including a quantitively EEG neural signal processing pipeline to extract features from the original signal datasets, machine learning models based on gradient boosted model for prediction. The tool can report electrographic seizures in real time during cEEG monitoring. The neonatologists will evaluate the neonates by AI-assisted cEEG diagnostic tool, clinical conditions, real-time cEEG and amplitude-integrated EEG traces. The investigators will make a decision after review the neonates clinical conditions, AI-assisted cEEG diagnostic report, the cEEG and amplitude-integrated EEG.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The routine assessment protocol
Description: The routine assessment protocol is that the neonatologists will evaluate the neonates by clinical conditions, real-time cEEG and amplitude-integrated EEG traces.
Study: NCT04751292

Intervention type: OTHER
Intervention: Exposure to high altitude
Description: permanence at high (\>2500 m) altitude; permanence is defined as being born and living at high altitude with the total time spent at lower altitudes not exceeding 2 years in the past 10 years
Study: NCT05080647

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mightier online gameplay
Description: Mightier is a video-game-based biofeedback intervention that capitalizes on children's love of video games to increase emotional awareness and facilitate emotion regulation practice through heart rate (HR) control. Each family receives a Mightier Kit (Mighty Band heart rate monitor, dedicated Mightier tablet unless the family prefers to use their own device) and the Mightier App. Children wear a Mighty Band heart rate monitor on their arm while they play any one of 26+ games. As their heart rate rises the games become more difficult. For example, during a cooking game, smoke may appear on the screen and obscure the player's view. Children can either opt into an explicit cool down activity (deep breathing, progressive muscle relaxation, crossing the midline, or visualization) or cool down on their own. By simply playing Mightier, children are motivated to practice calming strategies in moments of challenge.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mightier online gameplay
Description: Mightier is a video-game-based biofeedback intervention that capitalizes on children's love of video games to increase emotional awareness and facilitate emotion regulation practice through heart rate (HR) control. Each family receives a Mightier Kit (Mighty Band heart rate monitor, dedicated Mightier tablet unless the family prefers to use their own device) and the Mightier App. Children wear a Mighty Band heart rate monitor on their arm while they play any one of 26+ games. As their heart rate rises the games become more difficult. For example, during a cooking game, smoke may appear on the screen and obscure the player's view. Children can either opt into an explicit cool down activity (deep breathing, progressive muscle relaxation, crossing the midline, or visualization) or cool down on their own. By simply playing Mightier, children are motivated to practice calming strategies in moments of challenge.
Study: NCT06450496

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive parenting on-line program
Description: Positive parenting on-line program focused on parenting and personal competences relevant for parents with adolescents exhibiting mental health problems
Study: NCT06024824

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Dose-Painted Intensity Modulated Radiotherapy
Description: Fifteen fractions of external beam radiation therapy (EBRT) delivered via IMRT/ VMAT.~Cohort 1 (n = 3-6) Single PTV 40.05 Gy/15#, homogenous dose. Cohort 2 (n = 3-6) High Risk PTV 45 Gy/15# SIB to PTV tumour, Elective PTV 40.05 Gy/15# to nodal regions.~Cohort 3 (n = 3-6) High risk PTV 48 Gy/15# SIB to PTV tumour, Elective PTV 40.05 Gy/15# to nodal regions.
Study: NCT05518669

Intervention type: DEVICE
Intervention: Electromagnetic Navigation Bronchoscopy (superDimension™ Navigation System) and Mobile Cone-Beam CT (Cios Spin)
Description: Subjects with biopsy of peripheral pulmonary nodule using electromagnetic navigation bronchoscopy and mobile cone-beam CT.
Study: NCT06171672

Intervention type: OTHER
Intervention: Semi-structured interview
Description: Pediatric intensive care nurses in Hong Kong will be invited to join an individual in-depth semi structured interview.
Study: NCT05549648

Intervention type: OTHER
Group type: OTHER
Intervention: Home oral excrise
Description: The current study aimed to evaluate the efficacy and user experience of mobile phone APP, a mobile application with AI component in facial movement tracking, in improving oral functions of elderly people
Study: NCT05871021

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Dose escalation of radiation dose beyond the therapeutic standard
Description: Dose escalation to 75 Gy with concomitant radioprotectant bevacizumab
Study: NCT04695483

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Corifollitropin alfa
Description: Controlled ovarian stimulation long-acting protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Follitropin Beta
Description: Daily controlled ovarian stimulation protocol

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Follitropin Beta
Description: Daily controlled ovarian stimulation protocol
Study: NCT04834219

Intervention type: PROCEDURE
Intervention: On-Pump CABG
Description: Patients who have undergone on-pump Coronary artery bypass grafting (CABG) surgery are planned by the Department of Cardiovascular Surgery.
Study: NCT05298475

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Statin
Description: Medium-dose statin daily(atorvastatin 20mg qn or rosuvastatin 10mg qn)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Statin
Description: Medium-dose statin daily(atorvastatin 20mg qn or rosuvastatin 10mg qn)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Statin
Description: Medium-dose statin daily(atorvastatin 20mg qn or rosuvastatin 10mg qn)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PCSK9 inhibitor
Description: 1 injection of PCSK9 inhibitor once a month SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PCSK9 inhibitor
Description: 1 injection of PCSK9 inhibitor twice a month SC
Study: NCT04834219

Intervention type: PROCEDURE
Intervention: On-Pump CABG
Description: Patients who have undergone on-pump Coronary artery bypass grafting (CABG) surgery are planned by the Department of Cardiovascular Surgery.

Intervention type: PROCEDURE
Intervention: Off-Pump CABG
Description: Patients who have undergone off-pump Coronary artery bypass grafting (CABG) surgery are planned by the Department of Cardiovascular Surgery.

Intervention type: PROCEDURE
Intervention: Off-Pump CABG
Description: Patients who have undergone off-pump Coronary artery bypass grafting (CABG) surgery are planned by the Department of Cardiovascular Surgery.
Study: NCT05554614

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BTW app with reward-based feedback
Description: Teen drivers will be notified of their weekly driving performance via a driving safety score with information on the types of high-risk driving behaviors committed as well as progress on maintaining and/or improving weekly safe driving behaviors. Educational materials on different driving situations and scenarios associated with the high-risk driving behaviors (e.g. 90-second videos) will be provided for the driver to review at any point and time. Information on these driving behaviors and the education material will be provided via push notifications from the BTW app. Weekly leader boards will show the driver's driving safety score in comparison to other drivers of the same age. Consistently high driver safety scores in certain driving skill areas (e.g., cornering) and a total overall score above 70% of other users on that skill or total score will unlock gamification-based rewards (e.g., driving safety badges, driving safety score leader board, group challenges with winners).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BTW app with situational supervised driving practice
Description: Teen drivers will be provided bi-weekly push-notifications from the BTW app notifying them of situational supervised driving practice activities that are to be completed during the assigned week. There are 12 situational supervised driving activities and six skill-building driving activities (Table 1). Skill-building sessions are assigned for off weeks during the first half of the six months (weeks 2-12), allowing for skills to be further developed when the situations are encountered for a second time (weeks 15-23). Parents will be prompted to directly log situational supervised and skill-building driving activities in the app after the session within the BTW app to obtain the module completion date and duration time.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BTW app with situational supervised driving practice
Description: Teen drivers will be provided bi-weekly push-notifications from the BTW app notifying them of situational supervised driving practice activities that are to be completed during the assigned week. There are 12 situational supervised driving activities and six skill-building driving activities (Table 1). Skill-building sessions are assigned for off weeks during the first half of the six months (weeks 2-12), allowing for skills to be further developed when the situations are encountered for a second time (weeks 15-23). Parents will be prompted to directly log situational supervised and skill-building driving activities in the app after the session within the BTW app to obtain the module completion date and duration time.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham BTW app
Description: Teens will be provided links to passive education materials and information on car maintenance every week. They will not be given feedback on their driving performances.
Study: NCT05824741

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Infant Cardiovascular Health (CVH) Promotion
Description: The pilot infant CVH intervention will be delivered by Nurse-Family Partnership (NFP) staff starting no later than 1 month postpartum and lasting up to 6 months postpartum. The visit schedule will be consistent with the NFP visit structure to deliver intervention content at regularly scheduled visits that are typically 60 minutes long. This pilot study will include an enhanced version of the NFP standard care plan delivered by trained nurses to promote cardiovascular health by targeting soothing, feeding, sleep, and physical activity behaviors during infancy. The intervention delivered by trained visiting nurses will include behavior change strategies (e.g., goal setting, problem solving barriers). This pilot study will also examine the feasibility and acceptability of a digital device (infant foot worn actigraphy) during this same time period.
Study: NCT04832321

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey questionnaire
Description: Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey questionnaire
Description: Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey questionnaire
Description: Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey questionnaire
Description: Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey questionnaire
Description: Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey questionnaire
Description: Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.
Study: NCT04801953

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NiMODipine Injectable Solution
Description: nimodipine solution is applied to cranial nerves during resection of vestibular schwannoma

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sodium chloride solution is applied to cranial nerves during surgery
Study: NCT05713552

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock
Description: CONTROL

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock
Description: CONTROL

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
Description: TEST

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
Description: TEST