TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04980612

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Pain Reduction
Description: 40 participants will participate in a MBPR program. It will be an optimized mindfulness program specifically designed for treating cLBP that we will develop and test in this project. The format is the same as MBSR: 8 weeks of weekly 2½-hour group sessions and a daylong retreat.
Study: NCT06264024

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Corneal collagen cross linking (CXL)
Description: Use of Avedro Inc. KXL 1 system to stop progression of keratoconus

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Corneal collagen cross linking (CXL)
Description: Use of Avedro Inc. KXL 1 system to stop progression of keratoconus

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transepithelial phototherapeutic keratectomy (t-PTK)
Description: Use Alcon Wavelight 500, excimer laser to remove the epithelium and some of the stroma over apex
Study: NCT04980612

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness Based Stress Reduction
Description: 10 participants will participate in MBSR program. MBSR is a standardized and manualized 8-week program, delivered once a week in 2½-hour group sessions and a daylong retreat. It trains individuals in several mindfulness practices, e.g. focus on breath, varying degrees and directions of object orientation, open monitoring of awareness of intero- and exteroceptive stimuli and thoughts, de-reification (i.e. the notion that thoughts and perceptions are not always true to reality), and meta-awareness (i.e., awareness of thinking) in addition to focused attention.The program typically includes audio-recordings and a workbook for home practice and has shown benefits in patients with cLBP.
Study: NCT04900597

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Elecare Jr
Description: Elecare Jr is a standard pediatric elemental formula

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Elecare Jr
Description: Elecare Jr is a standard pediatric elemental formula

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Elecare Jr
Description: Elecare Jr is a standard pediatric elemental formula

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nourish
Description: Nourish is a commercially prepared blenderized tube feed that is formulated for pediatric use

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nourish
Description: Nourish is a commercially prepared blenderized tube feed that is formulated for pediatric use

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nourish
Description: Nourish is a commercially prepared blenderized tube feed that is formulated for pediatric use

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real Foods Blends
Description: Real Foods Blends is a commercially prepared blenderized tube feed that is formulated for pediatric use

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real Foods Blends
Description: Real Foods Blends is a commercially prepared blenderized tube feed that is formulated for pediatric use

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real Foods Blends
Description: Real Foods Blends is a commercially prepared blenderized tube feed that is formulated for pediatric use
Study: NCT05279846

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MOB015B
Description: Applied topically for 48 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle (Placebo Comparator)
Description: Applied topically for 48 weeks
Study: NCT04847973

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medically-Tailored Meals (MTMs)
Description: 12 weeks of home-delivered MTMs, delivered weekly, containing food for 3 meals per day on 5 days of the week

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein supplementation shakes
Description: 12 weeks of 1 bottle of Ensure Max Protein shake every day, in addition to partcipants' standard diet
Study: NCT05181527

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Selective Serotonin Reuptake Inhibitors
Description: Patients in both the study arms will receive SSRI for 8 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selective Serotonin Reuptake Inhibitors
Description: Patients in both the study arms will receive SSRI for 8 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dextromethorphan
Description: Patients in the test group will get Dextromethorphan 30 mg once daily orally as an add-on to ongoing SSRI treatment for 8 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients in the control group will get placebo tablet once daily orally as an add-on to ongoing SSRI treatment for 8 weeks.
Study: NCT05634863

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Implantable Doppler probe manufactured by COOK Medical Company.
Description: The continuous audible Doppler signals produced by the monitoring device represent the blood flowing in the renal artery. This is an indicator of graft perfusion. Cessation of audible Doppler signals is the key that may suggest hampered blood flow due to vascular complications. In the intervention group, the monitoring device will be used as an added mechanism to monitor graft perfusion.
Study: NCT06419140

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard SOX/XELOX adjuvant chemotherapy plus multimodal rehabilitation
Description: Motivational counseling to perform nutritional, psychological, and exercise inventions
Study: NCT06417619

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Psychoeducation
Description: The Effect of Mindfulness-Based Psychoeducation on Depression Level of Depression Patients
Study: NCT05543473

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vestibular Rehabilitation Therapy
Description: an exercise-based treatment program designed to promote vestibular adaptation and substitution. The goals of VRT are to enhance gaze stability, to enhance postural stability, to improve vertigo, and to improve activities of daily living. VRT facilitates vestibular recovery mechanisms: vestibular adaptation, substitution by the other eye-movement systems, substitution by vision, somatosensory cues, other postural strategies, and habituation
Study: NCT04732286

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab will be administered intravenously at a dose of 1200 mg on Day 1 of each 21-day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab will be administered by IV infusion at a dose of 15 mg/kg on Day 1 of each 21-day cycle.
Study: NCT05535881

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strengths to Grow Program
Description: In an online, self-directed format, the Strengths to Grow program will present the principles of strength-based parenting using videos, pictures, reflection questions, and written text. The intervention will communicate that a) every child has a unique set of strengths and that b) noticing and developing these strengths can enhance child and family well-being. It will also provide concrete steps that parents can follow to talk with their child about strengths, and it will provide ideas for family activities that would allow family members to express strengths. Participants will be invited to respond to reflection questions at various points throughout the program.
Study: NCT06107075

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Active
Description: 40g bio-active whey protein concentrate powder containing phospholipids

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: around 40g pea protein powder not containing phospholipids
Study: NCT05701332

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bacillus Calmette Guerin
Description: effect of local B.C.G and Gemcitabine on semen parametes and testicular volume
Study: NCT06194396

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chlorhexidine
Description: chlorhexidine will be used as skin disinfectant before insertion of CVC, PICC line, and umbilical catheter

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: alcohol
Description: alcohol will be used as skin disinfectant before insertion of CVC ,PICC line and umbilical catheter
Study: NCT05820425

Intervention type: OTHER
Intervention: LFP and EEG recording
Description: STN LFP and EEG recording during the OFF and ON medication condition
Study: NCT05422508

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Suduvax
Description: 0.5ml, single dose, subcutaneous injection
Study: NCT04789486

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGuIX
Description: Injected gadolinium-based nanoparticles

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGuIX
Description: Injected gadolinium-based nanoparticles

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Stereotactic magnetic resonance-guided adaptive radiation therapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Stereotactic magnetic resonance-guided adaptive radiation therapy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Stereotactic magnetic resonance-guided adaptive radiation therapy
Study: NCT03967548

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Germinal peptide eye drops
Description: Germinal peptide eye drops of 0.004%
Study: NCT05537805

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound guided transcervical fallopian tube catheterization during hysterosalpingo-foam sonography in the treatment of proximal tubal obstruction
Description: The intervention included the usage of the modified cornual cannulation set (COOK) which was inserted through cervical canal to uterine cavity, followed by fallopian tube irrigation with contrast foam (Ex-EM) during hysterosalpingo-foam sonography under ultrasonographic imaging.
Study: NCT05199259

Intervention type: DIAGNOSTIC_TEST
Intervention: Multi-analyte Blood Test
Description: A clinical diagnostic test based upon the detection and quantification of DNA methylation markers in cell-free DNA (cfDNA) isolated from plasma and of tumor-specific proteins isolated from serum.

Intervention type: DIAGNOSTIC_TEST
Intervention: Multi-analyte Blood Test
Description: A clinical diagnostic test based upon the detection and quantification of DNA methylation markers in cell-free DNA (cfDNA) isolated from plasma and of tumor-specific proteins isolated from serum.

Intervention type: DIAGNOSTIC_TEST
Intervention: Multi-analyte Blood Test
Description: A clinical diagnostic test based upon the detection and quantification of DNA methylation markers in cell-free DNA (cfDNA) isolated from plasma and of tumor-specific proteins isolated from serum.
Study: NCT06057363

Intervention type: OTHER
Intervention: volumetric evaluation of gingival augmentation around dental implants
Description: objective volumetric and clinical assesment of vestibular gingival soft tissues changes upon treatment with laser-aided pouch roll augmentation technique and implant placement over a 12-month follow-up
Study: NCT04986800

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PROACTIVE Parent
Description: PROACTIVE Parent will educate parents about their child's mental health symptoms and treatment, how to talk to the child's therapist to support treatment goals at home and in the community. PROACTIVE Parent will teach parents the function of child behavior, the role of symptomatology in child behaviors, and strategies to promote effective behavior management and healthy coping. Parents will also learn skills to manage their own emotional dysregulation to promote calm parental responding and promote healthy parent-child interaction and communication.
Study: NCT06196086

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography examination
Description: Echocardiography examination and software post-processing analysis was performed to obtain parameters of conventional echocardiography, left atrial and left ventricle strain, and IVP.

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography examination
Description: Echocardiography examination and software post-processing analysis was performed to obtain parameters of conventional echocardiography, left atrial and left ventricle strain, and IVP.
Study: NCT05506059

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound
Description: Participants will have ultrasounds of the heart by two different emergency medicine doctors.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Ultrasound
Description: Participants will have ultrasounds of the heart by two different emergency medicine doctors.
Study: NCT06501664

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: liposomal irinotecan
Description: Liposomal irinotecan 70 mg/m²

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5-FU
Description: 5-FU 400 mg/m² bolus then 2400 mg/m2 over 46 h

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-FU
Description: 5-FU 400 mg/m² bolus then 2400 mg/m2 over 46 h

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: LV
Description: LV 400 mg/m²

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LV
Description: LV 400 mg/m²

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Irinotecan
Description: Irinotecan 180 mg/m²
Study: NCT06499987

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: resection anastomosis
Description: resection of stenotic part of trachea and reanastmosis

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: resection anastomosis
Description: resection of stenotic part of trachea and reanastmosis
Study: NCT04890210

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Early Diet Group
Description: Initiation of clear fluid diet 1 hour after esophageal variceal ligation

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Late Diet Group
Description: Initiation of clear fluid diet 6 hours after esophageal variceal ligation
Study: NCT05586633

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: deep paravertebral periforaminal ozone injeciton
Description: Deep paravertebral periforaminal ozone injection was administered to the patients in the ozone injection group 4 times under ultrasound guidance, 10 ug/ml 5ml twice a week in the first week and 15 ug/ml 5ml twice a week in the second week.~Patients will be evaluated according to the study criteria at the beginning, at 15 days, 1 month, and 2 months. Physical examination findings were evaluated before starting the treatment and at the 2nd month follow-up.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: transforaminal steroid injeciton
Description: Transforaminal epidural steroid injection group, steroid (dexamethasone 8mg/2ml 2ml) injection was performed under the guidance of fluoroscopy.~Patients will be evaluated according to the study criteria at the beginning, at 15 days, 1 month, and 2 months. Physical examination findings were evaluated before starting the treatment and at the 2nd month follow-up.
Study: NCT05713097

Intervention type: DIAGNOSTIC_TEST
Intervention: TSI
Description: TSI was measured several times during the course of treatment when planning to stop medication (at the discretion of the attending physician).

Intervention type: DIAGNOSTIC_TEST
Intervention: TSI
Description: TSI was measured several times during the course of treatment when planning to stop medication (at the discretion of the attending physician).
Study: NCT05309863

Intervention type: BEHAVIORAL
Intervention: Lifestyle management
Description: Increasing the level of physical activity, dietary intervention, acquiring healthy eating habits, and psychological support.

Intervention type: BEHAVIORAL
Intervention: Lifestyle management
Description: Increasing the level of physical activity, dietary intervention, acquiring healthy eating habits, and psychological support.
Study: NCT06173193

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multicomponent exercise regimen
Description: A multicomponent exercise regimen applied is comprised of the step-aerobic and resistance training programs alternating every two weeks. The trainees participate in supervised training sessions 3 times a week for 8 months. Each session will include a 10-minutes warm-up, 30-minutes of effective training part and a 10-minutes period for cooling down.~Step-aerobic: The program includes accelerating and decelerating through forwards and sideways movements with stops and turns to music. The degree of difficulty of movements and steps as well as training intensity will be gradually increased by increasing the height of the step benches.~Resistance training: The participants will undergo a progressive resistance training program. Resistance training will emphasize training of following muscle groups: Quadriceps and hamstrings, hip abductors, adductors and extensors, and calf muscles. In addition to lower limb exercises, trunk and upper body exercises will be applied at intervals.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard rehabilitative management
Description: The treatments that will be provided to the members of a reference group represent the standard rehabilitative management for knee OA patients. The home exercises focus on functional exercises maintaining lower extremity flexibility and muscle function. The home exercises are instructed to be carried out three times a week, each work-out lasting 30 minutes.
Study: NCT05154292

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Serious Game: Emotional Health Island (SAEM)
Description: This intervention aims to aim to develop competencies for emotional regulation through exposure and acceptance strategies. This intervention is applied through a serious game developed for this purpose. the adolescent will complete a series of missions aimed at developing skills related to psychological flexibility, namely, greater psychological acceptance, mindfulness in the present moment, and committed actions in the direction of personal values. This serious game is guided by a therapist.
Study: NCT05626530

Intervention type: DRUG
Group type: OTHER
Intervention: Letermovir
Description: Open label 480 mg given daily for 60 days
Study: NCT04899297

Intervention type: OTHER
Intervention: Questionnaire
Description: All parents of patients visited at an outpatient service dedicated to the treatment of vertebral deformities will be recruited at the end of the medical clinical evaluation. The doctor will invite all subjects to complete the questionnaire anonymously at the end of each follow-up visit.
Study: NCT03670875

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Agave inulin
Description: Will be provided in dehydrated apple cubes

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Curcumin
Description: Will be provided in capsules

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: O3FA
Description: Will be provided in capsules

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control
Description: Dietary recommendations to ingest 1600 calories per day. Exercise: 30 minutes each day, al least 5 days a week (caloric consumption 150-200 kcal per day)
Study: NCT05196659

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Integrated comprehensive cardiovascular disease management
Description: 1. Electronic Health Record-Decision Support Software (EHR-DSS):~   * Electronic patient health record storage~  * Management prompts to the clinical team (following algorithms)~  * Structured follow-up schedule with automatic reminders to patients, clinical team, and non-physician health worker~2. Non-physician health worker-led continuity of care:~   - individually tailored follow-up and guidance regarding treatment adherence as well as help in resolving issues related to access, convenience, cost of care, and equity~3. Text-message based reminders for a healthy lifestyle~4. Patient diary containing visual assessment tool for adherence to medication (VITA) and reinforcement tool for lifestyle modification~5. Quarterly audit and feedback to the clinical team
Study: NCT05438316

Intervention type: DRUG
Group type: OTHER
Intervention: Ramipril tablet 10 mg
Description: Ramipril is manufactured by Pharmtechnology LLC, Republic of Belarus. Each tablet contains 10 mg of ramipril.

Intervention type: DRUG
Group type: OTHER
Intervention: Ramipril tablet 10 mg
Description: Ramipril is manufactured by Pharmtechnology LLC, Republic of Belarus. Each tablet contains 10 mg of ramipril.

Intervention type: DRUG
Group type: OTHER
Intervention: Tritace® tablet 10 mg
Description: Tritace® is manufactured by Sanofi-Aventis Deutschland GmbH, Germany. Each tablet contains 10 mg of ramipril.

Intervention type: DRUG
Group type: OTHER
Intervention: Tritace® tablet 10 mg
Description: Tritace® is manufactured by Sanofi-Aventis Deutschland GmbH, Germany. Each tablet contains 10 mg of ramipril.
Study: NCT04740047

Intervention type: DIAGNOSTIC_TEST
Intervention: Ion Endoluminal System
Description: Robotic bronchoscopy with c-arm imaging.
Study: NCT05464225

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: COSD
Description: The exercise protocol will include using the tongue to compress the COSD against the hard palate, or against the tongue depressor for 30 repetitions, 3 times per day, on 3 days of the 7-day week. For the first week, the participants who are in the COSD group will be issued a COSD bulb that corresponds to no less than 60% of their baseline maximum strength. After week 1, they will switch to a COSD bulb that corresponds to no less than 80% of their maximum tongue strength for the remaining 7 weeks.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SOC
Description: The exercise protocol will include using the tongue to compress the COSD against the hard palate, or against the tongue depressor for 30 repetitions, 3 times per day, on 3 days of the 7-day week. For the tongue depressor group, they will be given 8 tongue depressors, which are disposable, for the duration of the study.
Study: NCT04582578

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRT
Description: The experimental group will be treated with CRT in addition to optimal medical therapy for HF. In addition, the trial will further compare two methods of delivering CRT. One experimental group will receive BiV-CRT, while the second experimental group will receive CS-CRT

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRT
Description: The experimental group will be treated with CRT in addition to optimal medical therapy for HF. In addition, the trial will further compare two methods of delivering CRT. One experimental group will receive BiV-CRT, while the second experimental group will receive CS-CRT