TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04300985

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Patients will start receiving dexmedetomidine 15 minutes before general anesthetic induction.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Sham treatment
Description: Patients will start receiving saline solution infusion 15 minutes before general anesthetic induction.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium Sulfate
Description: Patient will start receiving magnesium infusion (20 mg/kg/h) 15 minutes before general anesthetic induction.
Study: NCT05987358

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3454 tablets
Description: TQB3454 is a selective IDH1 mutant enzyme inhibitor.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: TQB3454 tablets matching placebo
Description: Placebo tablets without active substance.
Study: NCT06528366

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Chlorella pyrenoidosa
Description: Functional food, organically pressed into tablets (Registration with Anvisa/MS/Brazil: 6.7273.000)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Definition Transcranial Direct Current Stimulation
Description: Neuromodulation Technics, non invasive, target and safety

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: High Definition Transcranial Direct Current Stimulation
Description: Neuromodulation Technics, non invasive, target and safety
Study: NCT04711655

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ARMA (antireflux ablation of the cardiac mucosa)
Description: is an endoscopy in which argon gas ablation of the cardiac mucosa

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: upper digestive endoscopy
Description: Quality diagnostic upper gastrointestinal endoscopy will be performed without intervention in patients assigned to this treatment arm.
Study: NCT06391554

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PRT
Description: An initial 12-week exercise intervention, consisting of 1-hour group sessions of progressive resistance training supervised by a physiotherapist 2 times per week. The sessions consist of a 10-minute submaximal warm up on an exercise bike followed by 50 minutes of PRT with exercises targeting the muscles of the hip and knee joints; leg press, hip extension, hip abduction, hip flexion and knee extension. The progression will be in line with guidelines provided by the American College of Sports Medicine. The intensity will follow repetition maximum (RM) targets, from 12 RM for the first week towards 8 RM for the last weeks. After the 12 weeks, participants will receive 8 booster sessions and are given a membership to a fitness center where they will be encouraged to continue the exercise program on their own.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: EDU
Description: Three EDU sessions provided by a trained physiotherapist involving important disease-specific information. The sessions will address knowledge of OA, treatment options with a specific focus on physical activity recommendations, advice on self-management and more. All three sessions will emphasize on engaging the participants actively and sharing experiences with each other.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EDU
Description: Three EDU sessions provided by a trained physiotherapist involving important disease-specific information. The sessions will address knowledge of OA, treatment options with a specific focus on physical activity recommendations, advice on self-management and more. All three sessions will emphasize on engaging the participants actively and sharing experiences with each other.
Study: NCT05416138

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS will be performed at either peaks or troughs of ongoing prefrontal theta oscillations (3-7 Hz) concurrently with the cognitive test at the beginning of every test trial. Theta oscillations will be monitored in real-time at the left dorsolateral prefrontal cortex using electroencephalography (EEG).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS will be performed at either peaks or troughs of ongoing prefrontal theta oscillations (3-7 Hz) concurrently with the cognitive test at the beginning of every test trial. Theta oscillations will be monitored in real-time at the left dorsolateral prefrontal cortex using electroencephalography (EEG).
Study: NCT06349564

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pico 4 Enterprise headset with noise cancelling headphones
Description: The device includes a computer tablet and virtual reality headset.
Study: NCT05963672

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EEG-guided sleep protection
Description: The tablet will display a specific picture prioritize sleep or prioritize care depending on the patient status determined by the algorithm. When the picture favor/prioritize sleep is displayed, all caregivers and visiting family are asked to follow the sleep protection rules: refrain to enter the room for not urgent reasons, switch off television, reduced light in the room/corridor, reduce noise in front of the door, close curtain (if any), and delay non urgent care...etc; if caregivers have to enter the room, headlight and/or additional light will be favored. All these rules will be established collegially by nurses and doctors. Obviously, urgent care and reactions to alarms are maintained.~When the picture favor/prioritize care is displayed, all caregivers and visiting family are invited to perform non urgent care, cleaning, restocking perfusion needles, comfort care, visiting.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Control condition
Description: the recording device will be placed on the patient to record sleep but the tablet will be masked and placed face down on the bench in the room, invisible from the door.
Study: NCT04688359

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guided Self Determination
Description: Nurse lead intervention in primary care
Study: NCT02528708

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fibrinogen concentrate
Description: The dose of fibrinogen concentrate needed to achieve this target will be calculated using a formula that accounts for the baseline FIBTEM® - A10 value and the patient's body weight assessed at hospital admission . In general, a 70-kg patient requires a fibrinogen dose of approximately 0.5 g to increase the MCF by approximately 1 mm.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% saline solution
Study: NCT05627271

Intervention type: OTHER
Intervention: ocrelizumab
Description: Non-interventional, cross-sectional, qualitative study. There is no treatment allocation. Patients prescribed with Disease-modifying therapy in the commercial setting are eligible to enroll into this study.

Intervention type: OTHER
Intervention: natalizumab
Description: Non-interventional, cross-sectional, qualitative study. There is no treatment allocation. Patients prescribed with Disease-modifying therapy in the commercial setting are eligible to enroll into this study.

Intervention type: OTHER
Intervention: ofatumumab
Description: Non-interventional, cross-sectional, qualitative study. There is no treatment allocation. Patients prescribed with Disease-modifying therapy in the commercial setting are eligible to enroll into this study.
Study: NCT05299476

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAPOX combined with bevacizumab and Tislelizumab
Description: Oxaliplatin: intravenous infusion, 130mg/m2, infusion for more than 3h, every 3 weeks for a cycle, infusion 4-8 cycles; Capecitabine: oral administration, 2g/m2, 2 times, 14 days, 7 days rest, every 3 weeks for a cycle; Bevacizumab was administered intravenously (without prophylaxis) at 7.5mg/kg. The first infusion was 90min, the second infusion was 60min, and each infusion was 30 min. The drug was administered once every 3 weeks, and the longest cumulative duration was 2 years.~Tislelizumab is administered intravenously (without prophylaxis) at a fixed dose of 200mg. Each infusion was 30 min (no less than 20 min, no more than 60 min), and the drug was given once every 3 weeks for a cycle, with the longest cumulative duration of 2 years.
Study: NCT05574296

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrogen
Description: Hydrogen gas (2%) in air or oxygen administered for 72 hours via ventilator and ECMO membrane. Oxygen concentration titrated per clinical team.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual care post-ECPR event, including targeted temperature management.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care post-ECPR event, including targeted temperature management.
Study: NCT05069103

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Similar to the original TWIST trial , patients will receive access to the online tool hosted on the ISLA platform until postoperative day 30 which is composed of two parts:~1. A series of simple questions related to the detection of surgical wound infection (e.g. redness, swelling, fluid leakage, etc). These questions would be expected to be routinely asked during in-person assessment, and these questions have been previously developed and tested within the TWIST trial (the only change being the addition of questions specifically relating to the change in these symptoms).~2. At least one image of their surgical wound(s).
Study: NCT05257278

Intervention type: DEVICE
Intervention: MonoPlus®
Description: MonoPlus® is indicated for use in general soft tissue approximation, specially in cases where extended wound support of more than 4 weeks is desirable
Study: NCT05963620

Intervention type: OTHER
Intervention: percutaneous coronary intervention vs bypass graft surgery
Description: retrieve long term follow up data on clinical outcome of study population, no intervention

Intervention type: OTHER
Intervention: percutaneous coronary intervention vs bypass graft surgery
Description: retrieve long term follow up data on clinical outcome of study population, no intervention
Study: NCT06264726

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HealtheRx
Description: CRx-CVD intervention provides participants with a HealtheRx, a tool developed by researchers with personalized listings of community resources with information about housing, food assistance, utility support, transportation and crisis support for patients. A HealtheRx may can be given directly, texted or emailed to patients and caregivers. All patients enrolled in this group will receive the HealtheRx either via text and/or email based on participant preference. Participants will receive contact information for a Community Resource Navigator who can provide support with using the HealtheRx, provide additional resources upon request, and answer any questions the participant may have. Participants will also receive a 2 reminder text messages over 2 months following their initial receipt of the HealtheRx. The SMS messages offer reminders about the HealtheRx and ongoing community resource navigation support.
Study: NCT06356402

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oral Health Educational Module for Mothers (OHEM) lecture
Description: OHEM via lecture will be delivered to the mothers by an oral health professional who will be instructed to teach their children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oral Health Educational Module for Mothers (OHEM) exhibition
Description: OHEM via exhibition will be delivered to the mothers who will be instructed to teach their children.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oral Health Educational Module for Mothers (OHEM) demonstration
Description: OHEM via demonstration will be delivered to the mothers by an oral health professional who will be instructed to teach their children.
Study: NCT05318001

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of plantar fascia
Description: The biomechanical (Tone-Hz, Stiffness-N/m and decrement) and viscoelastic (creep and relaxation time-ms) properties of the plantar fascia will be measured in the side lying position.~Measurements will be made with the ankle in neutral position.

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of plantar fascia
Description: The biomechanical (Tone-Hz, Stiffness-N/m and decrement) and viscoelastic (creep and relaxation time-ms) properties of the plantar fascia will be measured in the side lying position.~Measurements will be made with the ankle in neutral position.

Intervention type: OTHER
Intervention: Evaluation of biomechanics and viscoelastic properties of plantar fascia
Description: The biomechanical (Tone-Hz, Stiffness-N/m and decrement) and viscoelastic (creep and relaxation time-ms) properties of the plantar fascia will be measured in the side lying position.~Measurements will be made with the ankle in neutral position.

Intervention type: OTHER
Intervention: Evaluation of Foot Morphological Characteristics
Description: Foot length and width will be measured.

Intervention type: OTHER
Intervention: Evaluation of Foot Morphological Characteristics
Description: Foot length and width will be measured.

Intervention type: OTHER
Intervention: Evaluation of Foot Morphological Characteristics
Description: Foot length and width will be measured.

Intervention type: OTHER
Intervention: Evaluation of navıcular mobility
Description: The amount of navicular drop of both feet will be measured.

Intervention type: OTHER
Intervention: Evaluation of navıcular mobility
Description: The amount of navicular drop of both feet will be measured.

Intervention type: OTHER
Intervention: Evaluation of navıcular mobility
Description: The amount of navicular drop of both feet will be measured.

Intervention type: OTHER
Intervention: Evaluation of Foot Posture
Description: Foot posture will be evaluated according to Foot Posture Index.

Intervention type: OTHER
Intervention: Evaluation of Foot Posture
Description: Foot posture will be evaluated according to Foot Posture Index.

Intervention type: OTHER
Intervention: Evaluation of Foot Posture
Description: Foot posture will be evaluated according to Foot Posture Index.
Study: NCT05103826

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6390、Famitinib
Description: SHR6390, oral;Famitinib, oral.
Study: NCT05175092

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Living Donor Liver Transplantation
Description: The LDLT will be performed by the UW Division of Transplantation in accordance with the standard of care for this operation.
Study: NCT04694235

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Egg intervention
Description: Eggs are boiled until the white and yolk are firm (ca. 8 minutes) to maintain quality and safety and ensure the eggs are safe for consumption.
Study: NCT04688658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Nivolumab is a human IgG4 monoclonal antibody that blocks PD-1. It is a type of immunotherapy and works as a checkpoint inhibitor, blocking a signal that prevents activation of T cells from attacking the cancer.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Duvelisib
Description: Duvelisib is a potent inhibitor of both γ and δ isoforms. Duvelisib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Study: NCT05036304

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercise Indoors
Description: Each session will consist of 10 min of warm-up, 40 min of aerobic exercise, and 10 min of cool-down. Aerobic exercise will be progressive and of moderate intensity. During training, each participant will wear a heart rate monitor and will be asked to work initially at approximately 45% of his/her target heart rate (i.e., heart rate reserve (HRR)) and gradually progress to reach the target of 70% of HRR over the 12-week study period. Participants will also subjectively monitor workout intensity using the 20-point Borg's Rating of Perceived Exertion. Participants will walk or jog on treadmills or cycle on stationary bikes in the Exercise Prescription Suite of the Centre for Hip Health and Mobility.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise Outdoors
Description: Each session will consist of 10 min of warm-up, 40 min of aerobic exercise, and 10 min of cool-down. Aerobic exercise will be progressive and of moderate intensity. During training, each participant will wear a heart rate monitor and will be asked to work initially at approximately 45% of his/her target heart rate (i.e., heart rate reserve (HRR)) and gradually progress to reach the target of 70% of HRR over the 12-week study period. Participants will also subjectively monitor workout intensity using the 20-point Borg's Rating of Perceived Exertion. Participants will walk or jog pre-determined routes in trails of an urban forest (Pacific Spirit Park)
Study: NCT06401369

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lingual brackets
Description: These brackets will be used on the lingual surfaces of the upper and lower teeth.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Buccal brackets
Description: These brackets will be used on the vestibular surfaces of the upper and lower teeth.
Study: NCT05103007

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: DEB-TACE
Description: It is suggested that the tumor feeding artery should be selected for the microcatheter. The mixed volume of pirarubicin 80mg + microsphere 2g is about 2ml, and the mixture of at least 10ml and contrast medium is slowly injected with 5-10min.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PVL/PVE+DEB-TACE
Description: DEB-TACE will be performed after the liver function recovered within 7-10 days. After that, conventional transarterial chemoembolization（cTACE) was performed every 2 months, a total of 2-3 times of chemoembolization.
Study: NCT06440421

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MTL Labels
Description: The MTL label developed by the United Kingdom (UK) Food Standards Agency (FSA) includes per serving size information and grades each nutrient i.e., energy, sugar, fat, saturated fat, and sodium separately based on recommended thresholds. Green signifies a healthy amount of that nutrient; red signifies an unhealthy amount, and amber signifies that the nutrient levels fall between healthy and unhealthy amounts. Additionally, the label also shows how much of a person's daily allowance for a particular nutrient is met by consuming one serving of the product. Lastly, MTL includes the absolute values of each nutrient per serving of a product and the percentage of an adult's daily reference intake that is met by consuming a serving of this product. These will be displayed on all food and beverage products shown on this version of Bahrain e-Mart.
Study: NCT06162585

Intervention type: BIOLOGICAL
Intervention: Gene Therapy product-MCO-010
Description: Safety evaluation to monitor long term effects of previously injected MCO-010 in RP patients

Intervention type: BIOLOGICAL
Intervention: Gene Therapy product-MCO-010
Description: Safety evaluation to monitor long term effects of previously injected MCO-010 in RP patients
Study: NCT04900012

Intervention type: PROCEDURE
Intervention: Distal pancreatectomy
Description: We are going to collect all cases
Study: NCT06524609

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epigallocatechin-3-Gallate
Description: After determining the optimal dose, the efficacy of EGCG was compared with that of a control group (75% alcohol).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Alcohol
Description: After determining the optimal dose, the efficacy of EGCG was compared with that of a placebo control group (75% alcohol).
Study: NCT06464354

Intervention type: PROCEDURE
Intervention: The mammary artery harvesting by the pedicle technique
Description: The mammary artery harvesting by the pedicle technique was used in the LIMA pedicle study group.

Intervention type: PROCEDURE
Intervention: The mammary harvesting using the skeletonization technique
Description: The mammary harvesting using the skeletonization technique was used in the LIMA skeletonized study group.

Intervention type: PROCEDURE
Intervention: No intervention
Description: No intervention was used in the control study group.
Study: NCT06306833

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Surface Electromyography (sEMG) Biofeedback
Description: Biofeedback sEMG therapy through the use of virtual aids like digital therapeutics would help reduce chronic low back pain in patients by overcoming their psychophysiological manifestations. All participants in the intervention group will receive sEMG biofeedback as an alternative therapy.
Study: NCT05075746

Intervention type: DEVICE
Intervention: enVista Toric
Description: enVista Toric IOL

Intervention type: DEVICE
Intervention: enVista non-Toric (spherical)
Description: enVista non-Toric (spherical) IOL
Study: NCT05030181

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: kinesiotaping and exercise
Description: kinesiotaping group, ''I'' strip kinesiotape will be applied with the space correction technique for the upper trapezius muscle, for a total of 4 sessions, 2 days a week, and the patients will be included in the 1-month home exercise program.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercise
Description: exercise
Study: NCT05655884

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music Listening Application
Description: 15 minutes before going to the surgery, the child's favorite and chosen music piece will be loaded onto the mp3 player and played by the researcher via the creatone music pillow for 15 minutes. After the child returns to the service from the recovery room (the room where the patient is observed in the operating room for a certain period of time until he recovers from the surgery and his general condition is stable), and after he regains consciousness, music will be played by the music group again for 15 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Foot Reflexology Practice:
Description: Children in this group; Before going to the surgery, foot reflexology will be applied by the researcher, only to the left foot, for 10 minutes. After the child returns to the service from the recovery room (the room where the patient is observed in the operating room for a certain period of time until he recovers from the surgery and his general condition is stable), and after he regains consciousness, foot reflexology will be applied again, only on the left foot, for 10 minutes.