TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05630586

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Semaglutide
Description: Subcutaneous Semaglutide, 0.5 mg weekly for 4 weeks. First dose given at inclusion.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard care
Description: Treatment according to Danish national clinical guidelines on stroke treatment, including reperfusion therapy if eligible.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care
Description: Treatment according to Danish national clinical guidelines on stroke treatment, including reperfusion therapy if eligible.
Study: NCT06040242

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants will perform 3 min of the different activities, followed by a 10-min recovery window.
Study: NCT04510636

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab is a intravenously administered humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bendamustine Hydrochloride
Description: Bendamustine is a unique alkylating agent with substantial activity in hematologic malignancies.
Study: NCT06254196

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Telenursing interventions for monitoring Supportive Care Needs
Description: Use of the Intelligence2health platform, data collection forms on Google Forms, and dedicated telephone line for telenursing remote nursing monitoring interventions.~Based on the data, nurses will be able to implement patient education interventions aimed at preventing and monitoring healthcare support needs related to treatment.
Study: NCT06209385

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YZJ-5053 tablets
Description: YZJ-5053 tablets will be administrated orally QD for 21 days
Study: NCT05421650

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: CCRT
Description: 1. Radiation: Extended field-external beam radiation therapy (EF-EBRT) + brachytherapy + lymph node boost.~2. Chemotherapy: Cisplatin 40mg/m2, every week, 4 to 6 cycles.~3. Radiation and chemotherapy are administered concurrently.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical debulking of bulky or multiple lymph nodes
Description: 1. Open/minimally invasive method.~2. Surgical debulking of bulky or multiple lymph nodes.~3. Postoperative imaging evaluation to determine whether the lymph node has been successfully removed.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: CCRT
Description: 1. Radiation: EBRT/EF-EBRT + brachytherapy + lymph node boost.~2. Chemotherapy: Cisplatin 40mg/m2, every week, 4 to 6 cycles.~3. Radiation and chemotherapy are administered concurrently.
Study: NCT05604053

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivation Manipulation
Description: On some trials, participants have lower motivation and on other trials participants have higher motivation.
Study: NCT06095622

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fenugreek Seeds and Indian Rennet
Description: Food herbs like fenugreek Seeds and Indian rennet to formulate rice dish.
Study: NCT05958173

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Capsaicin
Description: Oral stimulation with natural TRPV1 agonist

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Piperine
Description: Oral stimulation with natural TRPA1/V1 agonist

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral stimulation with placebo solution
Study: NCT04932187

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine, Camrelizumab
Description: This is a single-arm study with all patients receiving these two drugs.
Study: NCT05562518

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Estrogen
Description: 1 vaginal ovule daily for three consecutive weeks, followed by 1 vaginal ovule 2 times per week

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dehydroepiandrosterone
Description: 1 vaginal ovule daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Estrogen + probiotics
Description: 2 vaginal ovules daily for 5 consecutive days, repeated every 4 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moisturizer
Description: 1 vaginal ovule daily for 10 consecutive days, followed by 1 vaginal ovule every three days
Study: NCT06181175

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PEAPROSTIL 600 + Tamsulosin 0.4 mg
Description: PEAPROSTIL 600 mg one sachet oral daily+ Tamsulosin 0.4 mg one tablet oral daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tamsulosin 0.4 mg
Description: Tamsulosin 0.4 mg one tablet oral daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PEAPROSTIL 600 mg
Description: PEAPROSTIL 600 mg one sachet oral daily
Study: NCT06189833

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab will be administered via a subcutaneous injection (SC)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Bortezomib will be administered via a subcutaneous injection (SC)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide will be administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone will be administered orally
Study: NCT06161623

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Laughter Yoga Application
Description: The intervention group took eight sessions of laughter yoga, that is, two sessions per week for 4 weeks. The participants in the intervention group were asked to fill in the data collection tools before the laughter yoga sessions, and after the 4th and 8th yoga sessions.
Study: NCT05852886

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Enable Oral Hygiene System (EOHS)
Description: The Enable Oral Hygiene System (EOHS) is a manual toothbrush comprised of a handle and shaft with multiple surfaces of synthetic bristles extending off of the shaft at one end.
Study: NCT06280183

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional Inspiratory Muscle Training
Description: Inspiratory muscle training is a technique that combines aerobic training with inspiratory muscle training. will be applied simultaneously with aerobic exercise. Participants will work with bicycle ergometry and then continue with IMT in the same session for the first three weeks. The intensity of IMT exercise will be set at 40-60% of MIP.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic+Resistive Exercise Traning
Description: Aerobic exercise is planned at 60-85% of the Maximum Heart Rate on a cycle ergometer for 30-40 minutes. Resistive exercise will cover all major muscle groups. The upper body (pectoralis, latissimus dorsi, rotator cuff muscles, deltoid, biceps, triceps), abdominal muscles, and lower extremities (quadriceps, hamstring, gastrosoleus) will be exercised to strengthen. For upper body, abdominal, and lower extremity muscles, 1-3 sets of 10-15 repetitions will be planned as 40-70% of 1 maximum repetition (1RM).
Study: NCT05935631

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Salt with folic acid and iodine
Description: Assess serum and RBC folate levels in women at baseline and 1 month after ingesting salt with folic acid
Study: NCT05536739

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robotic hip exoskeleton
Description: The intervention is an experimental robotic hip exoskeleton that has been previously developed by the team. It is used to improve walking gait performance.
Study: NCT05957003

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Combined end-expiratory occlusion and end-inspiratory occlusion test
Description: The EEO test will be performed by interrupting the mechanical ventilation at end-expiration over 15 seconds using the end-expiratory hold button available on the ventilator.~The EIO test will be performed by interrupting the mechanical ventilation at end-inspiration over 15 seconds using the end-inspiratory hold button available on the ventilator.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tidal volume challenge test
Description: elevating tidal volume from 6 ml/kg to 8 ml/kg for only 60 seconds
Study: NCT05560698

Intervention type: OTHER
Group type: OTHER
Intervention: Motivation-enhancing intervention
Description: The web app is designed as an efficient and easy-to-use app configurable to personal preferences. Each day participants receive a text message on their smartphone with a link for the daily cSMS questionnaire. The questionnaire addresses the same questions as the questionnaire in the standard intervention, but the format is different, and some shortcuts makes it easier to answer. When the questionnaire is answered, the web app gives access to different features. The following features distinct the motivation-enhancing intervention from the standard intervention (1) only complete the entire questionnaire on days with symptoms, (2) integration of grass pollen counts and forecasts, (3) showing personal response rate, (4) access to own data via a graph, (5) advice against grass pollen allergy, (6) status of the study, (7) individually choosing the time of response, (8) option to download an icon for the home screen and (9) contact information. The development is an ongoing iterative process

Intervention type: OTHER
Group type: OTHER
Intervention: Standard intervention
Description: Each day participants receive a text message on their smartphone with a link for the daily cSMS questionnaire. When the questionnaire is answered, the tab needs to be closed.
Study: NCT06013293

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Zinc oxide eugeonal based sealer
Description: Zinc oxide-eugenol (ZOE)- based preparations, which have been used in root canal obturation (RCO) for over a hundered years and are known for their antimicrobial activities.slight microleakage and zinc oxide-eugenol's superior antibacterial property,slight microleakage and concerning the lower cytotoxicity, the zinc oxide-eugenol (ZOE) sealer can be used for root canal obturation as an endodontic sealer.After root canal prepartion , the root canal will be dried with paper points and obturated using gutta-percha cones and zinc oxide eugenol sealer.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Resin Based Sealer
Description: resin-based sealer used frequently as a gold standard for endodontic sealers, due to its good physicochemical properties and provide satisfactory adhesion interface with dentin radicular surface.After root canal preparation, the root canal will be dried with paper points and obturated using gutta-percha cones and Resin based sealer
Study: NCT05230563

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ti-LUNG
Description: Participating clinicians will perform two image interpretations on all cases. One period the clinicians only will perform lung nodule detection on chest CT images, and the other period will perform lung nodule detection on chest CT images with the aid of Taihao lung CT decision support system. In each interpretation, all lung nodule is marked by each radiologist. This test collects chest computerized tomography cases for computer analysis, and evaluates whether the TaiHao lung CT decision support system helps doctors make more accurate diagnoses.
Study: NCT05641350

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Barlow's Unified Protocol
Description: Adaptation of the cognitive-behavioral Barlow's Unified Protocol for emotional eating pattern.
Study: NCT05555810

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: clipping or ligation of the cystic duct and the cystic artery in Laparoscopic cholecystectomy
Description: The investigators will make a comparison between clipping and ligation of cystic duct and cystic artery during Laparoscopic cholecystectomy and trying to know advantages and disadvantages of each technique .

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: clipping or ligation of the cystic duct and the cystic artery in Laparoscopic cholecystectomy
Description: The investigators will make a comparison between clipping and ligation of cystic duct and cystic artery during Laparoscopic cholecystectomy and trying to know advantages and disadvantages of each technique .
Study: NCT04720703

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Newsletters
Description: Similar to prior empirical pediatric obesity interventions (Elder et al., 2009), the active attention waitlist control group will receive monthly newsletters that focus on physical activity, healthy eating, and screen time. These newsletters will be based on standard materials from the We Can program of the National Heart, Lung, and Blood Institute (NHLBI).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family-based Telehealth Intervention
Description: All communications related to the intervention will occur through weekly small group video conferencing calls via Zoom and emails or text messages. The intervention will include diverse topics proven effective in prior interventions (Davis et al., 2019; McLean et al., 2003), including reading food labels, eating out, eating at social gatherings, sticker charts, praising/rewarding healthy choices, healthy foods available at home, portion sizes, healthy/easy/low-cost cooking ideas, goal setting, monitoring screen time, exercise opportunities available in neighborhood, family exercise ideas, and healthy sleep. The research team will also send relevant video/audio clips, brochures, reminders (text messages and emails) every week.
Study: NCT05987761

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PRT for Adolescents
Description: Clinician-led 70-minute PRT sessions targeting social skills once per week at Stanford.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PRT for Adolescents
Description: Clinician-led 70-minute PRT sessions targeting social skills once per week at Stanford.
Study: NCT06144008

Intervention type: BEHAVIORAL
Intervention: Answering questionnaire
Description: A questionnaires for each group has been developped and will be distributed for voluntary and anonymous completion.

Intervention type: BEHAVIORAL
Intervention: Answering questionnaire
Description: A questionnaires for each group has been developped and will be distributed for voluntary and anonymous completion.
Study: NCT06109545

Intervention type: PROCEDURE
Intervention: Laparoscopy
Description: Patients included in this study will have diagnostic laparoscopy type WOLF done after checking all above ultrasound parameters of malignant tumor. This procedure will be done under general anathesia then a verses needle will be used at umbilicus or at palmer point if the mass is large or in cases of umbilical hernia or previous abdominal or pelvic surgery, then Fagotti criteria will be assessed
Study: NCT05152186

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical Solution
Description: Topical administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Topical Solution
Description: Topical administration

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical Solution
Description: Topical administration

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical Foam
Description: Topical administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Topical Foam
Description: Topical administration

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical Foam
Description: Topical administration

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Topical
Description: Topical administration

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Topical
Description: Topical administration

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Topical
Description: Topical administration
Study: NCT05557214

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audit and Feedback Letter
Description: Physicians in the Audit and Feedback Letter Arm will receive an initial letter indicating their high prescriber status with guidance on reducing unnecessary antimicrobial use. They will also receive a follow-up letter at the 6 month mark indicating any change in prescribing habits. There will be a study closure letter mailed at the 12 month mark.
Study: NCT04976374

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine and Gabapentin
Description: Administration of intravenous dexmedetomedine for post operative analgesic purposes in combination with gabapentin
Study: NCT05596435

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT04976374

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Intravenous Saline 0.9% for placebo purposes
Study: NCT05326516

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Revumenib
Description: Participants will receive revumenib until meeting criteria for discontinuation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Revumenib
Description: Participants will receive revumenib until meeting criteria for discontinuation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy Regimen 1
Description: Participants will receive 2 treatment cycles of chemotherapy. During Cycle 1, participants will receive prednisone, vincristine, pegaspargase/calaspargase pegol-mknL, and daunorubicin. During Cycle 2, participants will receive etoposide and cyclophosphamide.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy Regimen 2
Description: Participants will receive 2 treatment cycles of chemotherapy. During Cycles 1 and 2, participants will receive fludarabine and cytarabine.
Study: NCT05502731

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Filgotinib
Description: Filgotinib is a small molecule that reversibly inhibits Janus kinases (JAK, selectively JAK 1), thereby inhibiting downstream signalling events induced by various pro-inflammatory and regulatory cytokines.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adalimumab
Description: Adalimumab is a monoclonal antibody selectively inhibiting the pro-inflammatory cytokine TNF-alpha.
Study: NCT05773456

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sushi and wakame salad
Description: One serving of mixed sushi and wakame salad

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sushi and wakame salad
Description: One serving of mixed sushi and wakame salad
Study: NCT05617170

Intervention type: OTHER
Intervention: Rehabilitation
Description: 50 case of acute cerebrovascular stroke patients will subject to implanted early rehabilitation programme based on telemedicine if avilable .~50 control patients of acute cerebrovascular stroke patients will subject to ordinary rehabilitation techniques .
Study: NCT04930380

Intervention type: OTHER
Intervention: phone interview
Description: Cases and controls will receive a phone interview

Intervention type: OTHER
Intervention: phone interview
Description: Cases and controls will receive a phone interview
Study: NCT05026190

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: transrectal ultrasound
Description: we perform trus to identify the cause of azospermia and its type either obstructive or not
Study: NCT06553859

Intervention type: OTHER
Intervention: No intervention conducts.
Description: The type and method of breast reconstruction with sillicon implants and ADM implanting is now the standard treatment of breast cancer in korea. no any specific intervention has occurred during the surgery.
Study: NCT06254820

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: influenza B/Connecticut/1/21 virus part a dose arm 1
Description: Medium dose, expected to be approximately 10\^6 tissue culture infective dose 50% (TCID50)/mL (titer may be adjusted based on stock titer)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: influenza B/Connecticut/1/21 virus part a dose arm 2
Description: High dose, expected to be approximately 10\^7 TCID50/ mL (titer may be adjusted based on stock titer)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: influenza B/Connecticut/1/21 virus part b dose 1
Description: Extension of one of the Part A dose arms; which one is to be determined (TBD) depending on outcome of Part A, AND/OR Dose Arm 3
Study: NCT05984927

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NG101 AAV gene therapy
Description: Sub retinal injection of NG101 (a non-replicating adeno-associated virus serotype 8 (AAV8) vector

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NG101 AAV gene therapy
Description: Sub retinal injection of NG101 (a non-replicating adeno-associated virus serotype 8 (AAV8) vector

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: NG101 AAV gene therapy
Description: Sub retinal injection of NG101 (a non-replicating adeno-associated virus serotype 8 (AAV8) vector
Study: NCT06434168

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yoga intervention
Description: Patients in the yoga group will receive a 60-minute session, twice per week over 12 weeks for a total of 24 sessions. Each yoga session consists of a warm-up, yoga postures standing or seated depending on the capability of the patient, and relaxation.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Control condition
Description: Patients in the control group will receive care-as-usual from their healthcare providers and will be asked to avoid engaging in yoga during their 3 months in the study.
Study: NCT04709549

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Prevention Program + Job and Legal Services
Description: Diabetes Prevention Program (DPP) is a one-year lifestyle modification program that helps adults at risk for developing type 2 diabetes gain tools for healthy living.~Job readiness services will be provided by YMCA SF service connectors, trained staff with expertise in employment services who are bi-lingual in English/Spanish and/or Cantonese/English to serve the needs of the community. Service Connectors will assist with providing employment services (e.g job search, potential placement and retention services, relationship development with partners and employers) and job readiness instruction/training.
Study: NCT06254820

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: influenza B/Connecticut/1/21 virus part b dose 2
Description: Addition of a 3rd dose, TBD depending on outcome of Part A
Study: NCT04709549

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diabetes Prevention Program
Description: Diabetes Prevention Program (DPP) is a one-year lifestyle modification program that helps adults at risk for developing type 2 diabetes gain tools for healthy living.
Study: NCT02179138

Intervention type: DRUG
Group type: OTHER
Intervention: TFV 1% gel
Study: NCT06046482

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given by IV (vein)