TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05005728

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: vudalimab + carboplatin + cabazitaxel
Description: Vudalimab IV, carboplatin IV, cabazitaxel IV

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: vudalimab + olaparib
Description: Vudalimab IV, olaparib oral

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: vudalimab monotherapy
Description: Vudalimab IV

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: vudalimab + docetaxel
Description: Vudalimab IV, docetaxel IV

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: vudalimab + cabazitaxel or docetaxel
Description: Vudalimab IV, cabazitaxel or docetaxel IV
Study: NCT05676749

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: C-TIL051
Description: C-TIL051 given in combination with IL-15 (NKTR-255) and pembrolizumab
Study: NCT05724394

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Culturally Adapted Getting Better Bite By Bite (Ca-GBBB) intervention
Description: The Ca-GBBB strongly focuses on enhancing participant's motivation and belief in their ability to change. The intervention will be comprised of 16-week training program delivered over four months.
Study: NCT05398094

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: AMG510 (Sotorasib) is small molecule that specifically and irreversibly inhibits the KRAS-G12C mutant protein. AMG510 (Sotorasib) finished product is presented as tablets containing 120mg and will be packaged in bottles of 120 tablets.
Study: NCT06674577

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atacicept 150 mg
Description: The atacicept drug product is available as a ready to use injection solution in the following prefilled syringe (PFS) that is composed of: \*BD Hypak™ SCF™ Barrel Glass barrel 1ml long with staked needle 27G ½ 5B with Rigid Needle Shield BD260 \*BD SCF™ Stopper 1ml long W4023 Flurotec
Study: NCT04771871

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epirubicin
Description: Epirubicin is an antitumor antibiotics with good activity on breast cancer. It has less cardiotoxic effect than doxorubicin
Study: NCT04771871

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Cyclophosphamide is a cytoxic drug indicated for the treatment of many malignancies including breast cancer

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a taxane chemotherapy agent indicated for the treatment of many cancers including breast cancer. It can be used alone or in combination with other drugs

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin is a platinum compound indicated for the treatment of many types of malignancies including breast cancer
Study: NCT05159011

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: AGILITY (Access to Genetic Information Leveraging Innovative TechnologY)
Description: information about genetic testing through technology
Study: NCT06487884

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: escape games
Description: A suitable day and time will be determined in the curriculum of the students in the intervention group and escape games consisting of various games involving intravenous drug administration will be played. Games will be played within the determined game guidelines. Each group will play the games at the stations respectively and get a clue at the end of each game. After completing the last game, the time it takes to find the password and complete the game will be recorded. After all groups complete the game, the group that completes the games in the shortest time will win the game and receive the prize in the chest.
Study: NCT05610839

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance-Enhanced Behavior Therapy
Description: 8-module intervention delivering acceptance-enhanced behavior therapy through a fully automated website. This intervention was adapted from the Acceptance-enhanced behavior therapy workbook (Woods \& Twohig, 2008).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Acceptance-Enhanced Behavior Therapy
Description: 8-module intervention delivering acceptance-enhanced behavior therapy through a fully automated website. This intervention was adapted from the Acceptance-enhanced behavior therapy workbook (Woods \& Twohig, 2008).
Study: NCT06158672

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional freedom technique group
Description: Menopausal women in the emotional freedom technique group will be administered the emotional freedom technique by the researcher a total of 4 times at one week intervals.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Sham emotional freedom technique group
Description: Menopausal women in the sham emotional freedom technique group will be administered sham emotional freedom technique by the researcher a total of 4 times with one week intervals.
Study: NCT04939896

Intervention type: OTHER
Intervention: observation
Description: Observed patients' compliance with rehabilitation at different time
Study: NCT06623084

Intervention type: OTHER
Intervention: Platelets characterization
Description: To identify platelet features that correlate with liver disease progression and to study the mechanistic relationship between gut dysbiosis, metabolome composition, inflammation, and platelet activation in chronic liver disease.

Intervention type: OTHER
Intervention: Platelets characterization
Description: To identify platelet features that correlate with liver disease progression and to study the mechanistic relationship between gut dysbiosis, metabolome composition, inflammation, and platelet activation in chronic liver disease.

Intervention type: OTHER
Intervention: Platelets characterization
Description: To identify platelet features that correlate with liver disease progression and to study the mechanistic relationship between gut dysbiosis, metabolome composition, inflammation, and platelet activation in chronic liver disease.

Intervention type: OTHER
Intervention: Platelets characterization
Description: To identify platelet features that correlate with liver disease progression and to study the mechanistic relationship between gut dysbiosis, metabolome composition, inflammation, and platelet activation in chronic liver disease.
Study: NCT06492876

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-003
Description: Administered via intraocular injection.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-003
Description: Administered via intraocular injection.

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: FT-003
Description: Administered via intraocular injection.
Study: NCT05393050

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colquhounia Root Tablet
Description: Colquhounia Root Tablet is a tripterygium preparation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methotrexate tablets
Description: Methotrexate is a drug used to treat rheumatoid arthritis

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methotrexate tablets
Description: Methotrexate is a drug used to treat rheumatoid arthritis
Study: NCT05180422

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AMG 510
Description: Continuous once daily (QD) oral dosing (Days 1-21 each cycle) with or without food.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MVASI
Description: Intravenous (i.v.) infusion every 21 days (i.e. Day 1 of each 21-day cycle).
Study: NCT05564091

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cataract surgery combined with ab-interno canaloplasty utililzing the iTrack Advance canaloplasty device
Description: 360 degree microcatheterization and viscodilation of Schlemm's canal
Study: NCT05916066

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Nicotinamide
Description: Tabletts of 500mg Nicotinamide (B3-vitamin)
Study: NCT05564091

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Cataract surgery
Description: Cataract surgery alone
Study: NCT06743126

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Albumin-Bound Paclitaxel
Description: in accordance with current respective prescribing information (PI) and/or summary of product characteristics (SmPC)
Study: NCT06745297

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 3776528
Description: BI 3776528

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo matching BI 3776528
Description: Placebo matching BI 3776528
Study: NCT06742294

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Movement education
Description: (1) providing preschool teachers professional development training in pedagogical knowledge and methods in the physical domain, (2) creating a set of teaching materials (in printed and digital formats) and methods that could be incorporated into the overall and preschool-based curricula, (3) creating a parental toolkit with contents mirroring the school materials, to enhance parents' knowledge and promote family-school collaboration, and (4) developing a smartphone-based artificial intelligence rating system to help preschool teachers conveniently and accurately assess children's motor skills, and provide appropriate instructional feedback.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Movement education
Description: (1) providing preschool teachers professional development training in pedagogical knowledge and methods in the physical domain, (2) creating a set of teaching materials (in printed and digital formats) and methods that could be incorporated into the overall and preschool-based curricula, (3) creating a parental toolkit with contents mirroring the school materials, to enhance parents' knowledge and promote family-school collaboration, and (4) developing a smartphone-based artificial intelligence rating system to help preschool teachers conveniently and accurately assess children's motor skills, and provide appropriate instructional feedback.
Study: NCT06758063

Intervention type: OTHER
Group type: OTHER
Intervention: exercises therapy
Description: exercises to improve balance of the body
Study: NCT06759792

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eye hand coordination exercises
Description: exercises to improve eye hand coordination post strabismus surgery
Study: NCT06754189

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Time Limited stimulation
Description: The participant self-administer 30 min. of electrical stimulation using Time Limited stimulation to the dorsal genital nerve (DGN) for 6 weeks using UCon with the UCon-Patch electrode.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: The participant self-administer 30 min. of sham stimulation to the dorsal genital nerve (DGN) for 6 weeks using a sham device with the UCon-Patch electrode.
Study: NCT06763016

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Theory-based group consultation
Description: The sessions focused on various topics, such as sexuality, sexual health, gender roles, and sexual violence. Participants were encouraged to engage in group discussions and complete weekly tasks, which allowed them to interact and reflect on the material presented. The intervention aimed to address and challenge prevalent sexual myths, encourage open discussions about sexuality, and foster healthier sexual attitudes through evidence-based counseling.~The content of the digital interventions was structured on the basis of a semi-structured interactive group counseling. It was supported by sharing content on Instagram, one of the most widely used social media tools of the generation representing.~For three days a week over six weeks, informative posts were shared, asynchronous testing and self-discovery activities were carried out, and a synchronous consultation session was held once a week. The participants were connected to the live broadcast of the research team.
Study: NCT05916066

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Nicotinamide
Description: Tabletts of 500mg Nicotinamide (B3-vitamin)

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Nicotinamide
Description: Tabletts of 500mg Nicotinamide (B3-vitamin)

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Nicotinamide
Description: Tabletts of 500mg Nicotinamide (B3-vitamin)
Study: NCT05257044

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabigerol
Description: Participants will ingest CBG and placebo in a double-blind randomized cross-over design

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT06758778

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: CreNeuroS CNS Fish Oil Plus Softgel [380 mg of fish oil contains Eicosapentaenoic Acid (EPA) （as EE）342 mg; L-5- Methyltetrahydrofolate 1.875 mg; other Vitamins and Minerals]
Description: Test product

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vascepa® (Icosapent ethyl) 1000 mg Capsules, Deplin® (L-methylfolate Calcium) 7.5 mg Capsules
Description: Reference product
Study: NCT06060080

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pegylated recombinant human granulocyte-colony stimulating factor
Description: Lymphoma/multiple myeloma patients who meet the inclusion criteria will be administered PEG-rhG-CSF injection at a fixed dose of 6 mg on the second day after hematopoietic stem cell infusion, and the effectiveness and safety of the treatment will be observed.
Study: NCT06124339

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical Activity
Description: There will be three sessions a week over the course of 16 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Activity (VR)
Description: There will be three sessions a week over the course of 16 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical and Cognitive Activity
Description: There will be three sessions a week over the course of 16 weeks.
Study: NCT04721834

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Low-intensity Extracorporeal Shockwave Therapy
Description: Low intensity shockwave energy would be delivered to stimulate angiogenesis in corporal tissue. Therapy would be delivered through a linear probe in 6 sessions. It would be conducted as a day procedure.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Therapy
Description: Same device as the active treatment arm would be used, with the addition of sham probe which block all shockwaves.
Study: NCT06779422

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pai.ACT
Description: The Pai.ACT mobile app is an innovative therapeutic tool that utilizes Acceptance and Commitment Therapy (ACT). It integrates a sophisticated algorithm to analyze self-reported data and conversation texts when the user interacts with the AI chatbot and identifies what psychological inflexibility processes are required to be the most essential to be addressed for process-matched ACT interventions. These interventions, including self-help modules and experiential exercises, are enhanced with dynamic animations and audio metaphors (see NCT06086951). The contents of Pai.ACT is underpinned by: (i) the core principles of Focused ACT, (ii) our validated Focused ACT protocol used in our ongoing Focused ACT trial (see NCT05803252), and (iii) our validated ACT protocols, established since 2019, that address psychological challenges specific to the Chinese parenting context (e.g., affiliate stigma, internalisation of external criticism, self-blame) through a 4-to-6 week of ACT.

Intervention type: OTHER
Group type: OTHER
Intervention: Positive parenting advice
Description: Positive parenting advice is recommended by the Child Assessment Services under the Department of Health, and videoconferencing session(s) led by another experienced counsellor for content revision. No access to AI chatbot/ACT modules will be granted.
Study: NCT06779123

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transauricular vagus nerve stimulation.
Description: TRAVAGUS is a portable electrical vagus nerve stimulator device that non-invasively activates the auricular branch of the vagus nerve in the left ear. The system consists of two units, the electrical stimulator and the ear electrodes that are mounted in a headset. The electrical signals are delivered transcutaneously to the ear via two separate cables connected to two aluminium electrodes. There is no need for electrode gel application on the auricular skin, since the conductivity of the two metallic electrodes is fully sufficient for functional electrical contact. The device is powered by 4 x 1,5V AAA batteries. The electrical source is a CE-marked tens unit termed STIM-PRO X9+, AXION GmbH, Leonberg, Germany. The investigational headset with auricular electrodes is designed and manufactured by taVNS AB in Saltsjö-Duvnäs, Sweden. Stimulation will be performed for 5 min twice daily for 12 weeks.
Study: NCT06072261

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesio tape application
Description: Before the standard rehabilitation program, kinesio taping was applied to both upper extremities in the form of a Y tape from the medial epicondyle to the wrist flexors, with 15-20% tension, to the patients hospitalized in the orthopedic service after lower extremity surgery. The tape should remain on the patient's arm throughout the hospital stay
Study: NCT05099991

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Single Foley Balloon
Description: Foley Balloon will be placed through the cervix and inflated with 30mL of saline or water on the day prior to the procedure

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Dilapan-S
Description: Dilapan S will be placed through the cervix on the day prior to the procedure
Study: NCT05491642

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY3283142
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY3283142
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY3283142
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo to BAY3283142
Description: Oral administration
Study: NCT06779123

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: transauricular vagus nerve non-stimulation
Description: TRAVAGUS is a portable electrical vagus nerve stimulator device that non-invasively activates the auricular branch of the vagus nerve in the left ear. The system consists of two units, the electrical stimulator and the ear electrodes that are mounted in a headset. The device is placed to the ear but no stimulation will occur. The procedure is performed for 5 min twice daily for 12 weeks.
Study: NCT05491642

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo to BAY3283142
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo to BAY3283142
Description: Oral administration
Study: NCT05102981

Intervention type: PROCEDURE
Intervention: emergency procedure
Description: The difference between groups is the timing or type ie emergency as opposed to planned

Intervention type: PROCEDURE
Intervention: emergency procedure
Description: The difference between groups is the timing or type ie emergency as opposed to planned
Study: NCT05253235

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SAAF
Description: A 7 session online intervention designed to augment protective processes associated with deterrence of substance use

Intervention type: OTHER
Group type: OTHER
Intervention: Receipt of parenting book
Description: Parents will receive a copy of the book, Parenting for Liberation: A Guide for Raising Black Children
Study: NCT05587374

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: Cadonilimab 10mg/kg will be given every 3 weeks for 3 cycles in induction chemotherapy and for 14 cycles in adjuvant chemotherapy, started on day 1 of induction chemotherapy and adjuvant chemotherapy, respectively.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine 1g/m2, d1 \& 8 of every cycle, every 3 weeks for 3 cycles before radiation.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gemcitabine
Description: Gemcitabine 1g/m2, d1 \& 8 of every cycle, every 3 weeks for 3 cycles before radiation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Induction cisplatin 80mg/m2, every 3 weeks for 3 cycles before radiation; Concurrent cisplatin 100mg/m2, every 3 weeks for 2 cycles during radiation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: Induction cisplatin 80mg/m2, every 3 weeks for 3 cycles before radiation; Concurrent cisplatin 100mg/m2, every 3 weeks for 2 cycles during radiation

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity-modulated radiotherapy
Description: Definitive intensity-modulated radiotherapy (IMRT) of 6996cGy will be given in 33 fractions.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Intensity-modulated radiotherapy
Description: Definitive intensity-modulated radiotherapy (IMRT) of 6996cGy will be given in 33 fractions.
Study: NCT06508034

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo stool and blood sample collection

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Live Freeze-Dried Lactic Acid Bacteria Probiotic
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT05528133

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Genomically Guided Radiation Therapy
Description: Participants will receive treatment 5 days per week, in once daily fractions. The total dose will be 50 Gy in 25 fractions or 42.56 Gy in 16 fractions with or without a boost of 10 Gy in 5 fractions to the cavity.
Study: NCT05507892

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: canagliflozin
Description: Canagliflozin is in a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It is a used to treat type 2 diabetes. Canagliflozin lowers blood sugars by causing the kidneys to excrete more glucose in the urine.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aminohippurate Sodium Inj 20%
Description: Diagnostic aid/agent used to measure renal plasma flow (RPF) PAH (Basic Pharma, Geleen, Netherlands) has been used to measure RPF in human research for 7 decades, and is very well tolerated and generally recognized as safe with low toxicity.
Study: NCT06539377

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Living donor liver transplantation
Description: Liver transplantation from living donor donation (SII/III as left-lateral donation during a two stage-procedure or left lobe donation or right lobe donation) in patients with unresectable intrahepatic cholangiocarcinoma.