TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04293978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CalmPlace
Description: Self-contained VR application allowing the user to build and custom a relaxation session, with options to vary session length (9-20 minutes), music/sound, relaxation exercises, and specific nature environment (three available) including time of day and events (e.g. rain). Delivered using an Oculus Go devices in kiosk-mode.
Study: NCT06181799

Intervention type: DIAGNOSTIC_TEST
Intervention: Mass spectrometry using the PTR TOF-1000 (IONICON PTR-TOF-MS - Trace VOC Analyzer, Eduard-Bodem-Gasse 3, 6020 Innsbruck, Austria (Europe).
Description: Once enrolled in the study, all participants are scheduled to undergo the following tests:~The analysis of volatile organic compounds obtained from exhaled air will be carried out by a combination of real-time analytical methods, the use of a real-time mass spectrometer with ionization by the proton transfer method. Machine learning models will be employed to analyze the patterns identified in the exhaled air volatilome data.~Before and immediately after the exercise test, all patients are scheduled to record a single-lead ECG and pulse wave, using a portable single-lead recorder (Cardio-Qvark) (Russia, Moscow). Single lead-ECG and pulse wave parameters will be interpreted using machine learning models.

Intervention type: DIAGNOSTIC_TEST
Intervention: Mass spectrometry using the PTR TOF-1000 (IONICON PTR-TOF-MS - Trace VOC Analyzer, Eduard-Bodem-Gasse 3, 6020 Innsbruck, Austria (Europe).
Description: Once enrolled in the study, all participants are scheduled to undergo the following tests:~The analysis of volatile organic compounds obtained from exhaled air will be carried out by a combination of real-time analytical methods, the use of a real-time mass spectrometer with ionization by the proton transfer method. Machine learning models will be employed to analyze the patterns identified in the exhaled air volatilome data.~Before and immediately after the exercise test, all patients are scheduled to record a single-lead ECG and pulse wave, using a portable single-lead recorder (Cardio-Qvark) (Russia, Moscow). Single lead-ECG and pulse wave parameters will be interpreted using machine learning models.
Study: NCT06492200

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psyllium husks
Description: Patients in the intervention group will receive nutritional counseling and will be asked to take 10g (one tablespoon) of ground psyllium husks daily to significantly increase the fiber content of their diet.
Study: NCT05953753

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Food system and demand generation
Description: The project is focused on improving egg consumption through enhanced availability, accessibility, and improved demand. To achieve this goal, the project intervention mix will work through three pathways: access, enabling environment, and demand. The access pathway aims to sustain availability and consumption of eggs by school children (age 6-9 years) from BoP households through interventions targeted at the Poultry Association of Nigeria (PAN) and state lead egg aggregators for the HGSFP. The enabling environment pathway focuses on the broader institutional, governance, and political factors to support accessibility, availability, improved consumption, and increased consumer demand for eggs. The demand pathway will be addressed by mass media and interpersonal communication to increase the willingness and motivation of parents/caregivers in BoP households to support and sustain egg consumption by pre-school children in Kaduna State.
Study: NCT06289803

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: probe confocal laser endomicroscopy
Description: probe confocal laser endomicroscopy will be used to identify the tumor behavior
Study: NCT04594746

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amiodarone Hydrochloride
Description: Amiodarone hydrochloride 2000 mg PO to be given as a 10-capsule dose pack and ingested in a single sitting with food

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral placebo to be given as a 10-capsule dose pack and ingested in a single sitting with food
Study: NCT04282850

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary Vein Isolation
Description: The intervention will involve standard of care electrophysiology ablation for rhythm management of atrial fibrillation with a procedure called a pulmonary vein isolation.
Study: NCT05922930

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TROP2-CAR-NK
Description: Given by IP (intraperitoneal)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given by IV (vein)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Given by IV (vein)
Study: NCT06020521

Intervention type: OTHER
Group type: OTHER
Intervention: Three spectrometry differents technics
Description: Collection of expired air as follows:~* For online mass spectrometry techniques (PTR-MS and SICRIT)~* For offline mass spectrometry (GCxGC-MS)~Performing volatolome analyses:~* By PTR-TOF-MS (Ionicon) and SICRIT-HRMS (SICRIT module (Plasmion) coupled to a Q-exactive instrument (Thermofisher)) for online analyzes~* By two-dimensional gas chromatography coupled with mass spectrometry (Pegasus BT-4D, Leco) for the desorption tubes.
Study: NCT05772325

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Individually tailored diet counseling
Description: Participants in the intervention group will receive a 60 min individually tailored heart-friendly diet consultation by a dietitian

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The brief standardized 4-minute heart healthy dietary advice
Description: The brief standardized 4-minute heart healthy dietary advice will be provided by an experienced cardiologist or rheumatologists
Study: NCT06219252

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraoperative aberrometer
Description: the patient intraocular lens will be optimized during the aphakic period after cataract extraction and before intraocular lens implantation, this will produce a possible change in the dioptric power of the intraocular lens

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preoperative intraocular lens calculation
Description: the intraocular lens in this group will be calculated preoperatively with Barrett Universal II formula
Study: NCT06341881

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transitional Care Training Program
Description: A nursing based transitional care training intervention would be carried out to prepare the family caregivers to take care of their elderly stroke survivors at home. The intervention would be carried out for a tentative time of 2 to 3 hours to educate the family caregivers at their homes after hospitalization. The study participants would be evaluated after 8 weeks of the intervention. A structured, validated and literature based assessment checklist will be devised to assess the usefulness and feasibility of the intervention. Assistance of senior nurses and health professionals, specialized in stroke care will be taken during the training part of the program.
Study: NCT06119503

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Elongating Time HOrizons for Reentry (ETHoR)
Description: The adapted episodic future thinking (EFT) intervention will focus on generation of vivid, substance-free, rewarding events that could happen in an incarceration free future.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standardized Episodic Thinking (SET)
Description: In the standardized episodic thinking (SET) condition, the participant will instead describe in vivid details events that have occurred in the recent past.
Study: NCT06654037

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tissue biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Given IV
Study: NCT06376864

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Activity Breaks
Description: The Activity Breaks intervention is a 5-minute Activity Breaks programme that allows classroom teachers of all ages and ability levels to lead simple movement activities within their classrooms, negating the need for additional personnel or space.
Study: NCT05202262

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BFF MDI 320/9.6 μg
Description: Budesonide/ Formoterol Fumarate (BFF) metered-dose inhaler (MDI), 320/9.6 μg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BFF MDI 160/9.6 μg
Description: Budesonide/ Formoterol Fumarate (BFF) metered-dose inhaler (MDI), 160/9.6 μg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BD MDI 320 μg
Description: Budesonide MDI (BD MDI), 320 μg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Open-label Symbicort TBH 320/9 μg
Description: Open-label Symbicort Turbuhaler 320/9 μg
Study: NCT06007027

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SmartXIDE2V2LR, Monalisa Touch, DEKA, Florence, Italy
Description: The laser probe is gently inserted up to the top of the vagina, and subsequently withdrawn and rotated in order to deliver a complete treatment of the vaginal wall.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SmartXIDE2V2LR, Monalisa Touch, DEKA, Florence, Italy
Description: The laser probe is gently inserted up to the top of the vagina, and subsequently withdrawn and rotated in order to deliver a complete treatment of the vaginal wall.
Study: NCT05278520

Intervention type: PROCEDURE
Intervention: Total hip arthroplasty
Description: Hip joint replacement surgery. Elective for RA and OA cases.

Intervention type: PROCEDURE
Intervention: Total hip arthroplasty
Description: Hip joint replacement surgery. Elective for RA and OA cases.

Intervention type: PROCEDURE
Intervention: Total hip arthroplasty
Description: Hip joint replacement surgery. Elective for RA and OA cases.
Study: NCT06692361

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FMT capsule
Description: The experimental group will maintain escitalopram treatment and take 1.0 g of FMT capsules orally with breakfast every day for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram (Lexapro)
Description: Both the experimental group and the placebo group were treated with the maximum tolerated dose of escitalopram.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Escitalopram (Lexapro)
Description: Both the experimental group and the placebo group were treated with the maximum tolerated dose of escitalopram.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Corn Starch capsules
Description: The placebo group will maintain escitalopram treatment and take corn starch capsules 1.0 g orally with breakfast every day for 4 weeks.
Study: NCT06702059

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiopulmonary exercise testing
Description: Subjects will undergo pre-operative cardiopulmonary exercise testing.
Study: NCT06715722

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: hexed non hexed
Description: A 3-unit screw-retained implant bridge over two conical internal hex implants will be supported using one hexed and one non-hexed abutment.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: non-hexed non-hexed
Description: a 3-unit screw-retained implant bridge over two conical internal hex implants will be supported using two non-hexed abutments
Study: NCT06715995

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
Description: Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
Description: Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.
Study: NCT06719466

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: low linoleic acid (LA)
Description: diet guidance with low linoleic acid (LA) diet
Study: NCT06715982

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JAK Inhibitor
Description: JAK inhibitors for 28 days
Study: NCT06715657

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine intrathecal
Description: patients intrathecal anaesthesia with morphine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine intrathecal
Description: patients intrathecal anaesthesia with morphine

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Morphine intrathecal
Description: patients intrathecal anaesthesia with morphine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: propofol
Description: patients will receive 0.5 mg/kg propofol diluted in 10 ml saline 0.9% IV injection 15 min before the end of surgery

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: propofol
Description: patients will receive 0.5 mg/kg propofol diluted in 10 ml saline 0.9% IV injection just before intrathecal anaesthesia
Study: NCT06716684

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Approach Based Psychoeducation Program
Description: A 6 session cognitive-behavioral approach based psychoeducation program developed in line with the literature review is applied in the research. Group training sessions have been held once a week with each session 90 minutes on average. The techniques such as automatic thought recording, finding cognitive errors, thought-stopping, forming alternative thoughts, daydreaming, countdown, problem solving, role playing, modeling, deep breathing, relaxation exercises, summarizing, explaining, informing, homework were used in the sessions.
Study: NCT06717373

Intervention type: DEVICE
Group type: OTHER
Intervention: AutoAS
Description: AutoAS is an artificial intelligence algorithm that will be tested retrospectively on the images acquired as part of the study
Study: NCT06718192

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bleomycin injection
Description: Wart injection (0.2 mL \<5 mm; 0.5 mL 5-10 mm; 1ml for \>10 mm) were injected at a depth of 1.5mm, diluted with normal saline at a concentration of 3u/ml=3mg/ml, and the maximum amount of each wart was 1ml until the wart turned white

Intervention type: OTHER
Group type: OTHER
Intervention: Cryotherapy
Description: The wart was frozen by liquid nitrogen until a circle of frozen tissue appeared around the wart for about 10s, with an interval of 30s, for a total of 2 times
Study: NCT06719388

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: combination of exercise therapy and a jaw-mobilizing device
Description: Participants in the experimental group will receive a combination of exercise therapy and a jaw-mobilizing device. The intervention includes structured exercise therapy sessions and the use of the jaw-mobilizing device for 12 weeks, beginning one week prior to radiotherapy. Follow-ups will occur at weeks 16, 24, and 36 to assess outcomes.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: exercise therapy only
Description: Participants in the control group will receive exercise therapy only. This intervention involves the same structured exercise therapy sessions as the experimental group for 12 weeks, beginning one week prior to radiotherapy. Follow-ups will occur at weeks 16, 24, and 36 to assess outcomes.
Study: NCT06717958

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivosidenib 250 MG (milligram)
Description: oral
Study: NCT06714682

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Modified Pectoral Plane block group
Description: The patient will lay supine with the ipsilateral arm abducted and externally rotated and the elbow flexed at 90 degrees. The probe will be placed transversely between the clavicle medially and above and the shoulder joint laterally. After identifying the pectoralis major and minor muscles and the plane between them, the probe will be pushed 1-2 cm caudally and medially. In a caudal tilt, within a biconvex space, the artery will be recognised. After that, the block needle will be inserted in an in-plane approach to the artery's location and 10 mL of 0.25% bupivacaine will be administered Then probe will be moved laterally and caudally towards the anterior axillary fold until the serratus muscle appears beneath the pectoralis minor muscle attaching to the underlying ribs. The needle will target the plane between pectoralis minor and serratus muscles at the level of the third rib, followed by negative aspiration into the fascial plane then injection of 10 mL of 0.25 bupivacaine.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector spinae plane block group.
Description: The block will be performed with the patient in a sitting position , The high-frequency linear probe will be placed in a longitudinal orientation 3 cm from the midline. Once the erector spinae muscle and the transverse processes identified, the block needle will be inserted in a caudad-to-cephalad direction until the tip lay in the interfacial plane deep to the erector spinae muscle, 20 mL of 0.25% bupivacaine will be administered for block performance.
Study: NCT06719245

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Targeted Muscle Reinnervation (TMR)
Description: In short: each transected nerve is identified after amputation and is dissected proximally for length. A nerve stimulator is used to identify functional motor nerve branches. Near the point where the motor branch enters the muscle, the motor nerve branch is transected and an end-to-end coaptation is performed with a nearby amputated nerve.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Standard neurectomy
Description: During the amputation a standard neurectomy will be performed based on the surgeons preference. Standard neurectomy will include cutting of the nerve, with or without traction, with or without coagulation, and with or without infiltration with a local anesthetic (i.e., ropivacaine) or phenol. Ligation of the nerve will not be allowed.
Study: NCT06715202

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patient Education Booklet
Description: Before the surgery, a personal information form and the SF-36 Quality of Life Scale will be filled out. The educational content regarding the problems that these patients may encounter with the DJ stent after the surgery until they are discharged will be explained in sections and the patients' questions will be answered. When the patient comes to the hospital for DJ stent removal 4 weeks after discharge, the Ureteral Stent Symptom 1st Questionnaire and the SF-36 Quality of Life Scale will be filled out while the DJ stent is in place. The Ureteral Stent Symptom 2nd Questionnaire and the SF-36 Quality of Life Scale will be applied 4 weeks after the stent is removed. The education booklet will be prepared by the researchers in accordance with the recommendations of the European Association of Urology and the relevant literature.
Study: NCT06716554

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Shatavari extract
Description: Shatavari is scientifically known as Asparagus racemosus. One capsule containing Shatavari 300mg should be taken once daily.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Shatavari + Ashwagandha extract
Description: Shatavari is scientifically known as Asparagus racemosus along with Ashwagandha root extract scientifically known as Withania somnifera. One capsule containing Shatavari 300mg + Ashwagandha root extract 250mg should be taken once daily.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (starch)
Study: NCT06715215

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Acute phase proteins
Description: Assessment of acute phase proteins levels in patients diagnosed with immune thrombocytopenia

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Acute phase proteins
Description: Assessment of acute phase proteins levels in patients diagnosed with immune thrombocytopenia

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Acute phase proteins
Description: Assessment of acute phase proteins levels in patients diagnosed with immune thrombocytopenia
Study: NCT06718179

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Short duration of aspirin and prasugrel
Description: aspirin 75 mg/day for 1 months plus prasugrel 10 mg/day (5 mg/day) for 1 year, followed by lifelong aspirin 75 mg/day after 1 year

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Conventional duration of aspirin and prasugrel
Description: aspirin 75 mg/day lifelong plus prasugrel 10 mg/day (5 mg/day) for 1 year
Study: NCT06718400

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sentinel Skin Flap
Description: Willing participants who will be receiving an intestinal transplantation will receive a sentinel skin flap on their forearm from the same donor
Study: NCT06716840

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam
Description: participants in the remimazolam group received remimazolam besylate intravenously at an initial infusion rate of 0.2mg/kg/h and adjusted (maximum of 2 mg/kg/h) to maintain a Richmond Agitation-Sedation Scale(RASS) score between - 2 and 0.If the maximum dose of remimazolam was insufficient to sedate, add rescue dexmedetomidine.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: participants in the propofol group received propofol intravenously at an initial infusion rate of 1 mg/kg/h and adjusted (maximum of 4 mg/kg/h) to maintain a Richmond Agitation-Sedation Scale (RASS) score between - 2 and 0.If the maximum dose of propofol was insufficient to sedate, add rescue dexmedetomidine.