TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06385717

Intervention type: RADIATION
Intervention: chemo-radiation
Description: different Chemo-radiotherapy regimen

Intervention type: RADIATION
Intervention: chemo-radiation
Description: different Chemo-radiotherapy regimen

Intervention type: RADIATION
Intervention: chemo-radiation
Description: different Chemo-radiotherapy regimen
Study: NCT04732611

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walking protocol
Description: Walking group participants will perform 3 weekly walking sessions lasting approximately 50 minutes for 20 weeks.
Study: NCT05484817

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of cardiovascular risk factor, endocrine hormones and related biomarker
Description: Cardiovascular risk factors: glycated hemoglobin/C-peptide/continuous glucose monitoring/blood pressure, blood lipids, uric acid, microalbumin test, etc. Endocrin hormones: bone metabolism, sex hormones, adrenal and pituitary hormones, and related biomarkers

Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of cardiovascular risk factor, endocrine hormones and related biomarker
Description: Cardiovascular risk factors: glycated hemoglobin/C-peptide/continuous glucose monitoring/blood pressure, blood lipids, uric acid, microalbumin test, etc. Endocrin hormones: bone metabolism, sex hormones, adrenal and pituitary hormones, and related biomarkers
Study: NCT04588506

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Lower Trapezius Tendon Transfer Technique
Description: Lower Trapezius tendon used in repairing cuff tear

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Latissimus Dorsi Tendon Transfer Technique
Description: Latissimus Dorsi tendon used in repairing cuff tear

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Latissimus Dorsi Tendon Transfer Technique
Description: Latissimus Dorsi tendon used in repairing cuff tear

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pectoralis Tendon Transfer Technique
Description: Pectoralis tendon used in repairing cuff tear
Study: NCT05648149

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: hierarchical multi-dimensional cognitive training scheme based on computer
Description: The scheme was constructed five main categories of cognitive function: (1) attention, memory, numeracy, thinking response and perception; (2) There are 10 training items, which are drawing, quick matching, flash memory, number memory, face memory, color tracking, number span, word naming, symbol number form, quick arithmetic; (3) Each training item is divided into basic and advanced training. Only if the basic training reaches more than 80%, can the advanced training be entered; (4) In order to facilitate patient training, all items were embedded in the wechat mini program, and corresponding cognitive training was carried out in the mini program; (5)Small program background can monitor training results.
Study: NCT04528459

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Stryker© ADAPT™ platform
Description: The ADAPT system is a software platform that utilizes augmented reality to assist surgeons with implant alignment, lag screw length and positioning, and distal interlocking screw placement for cephalomedullary fixation of peritrochanteric femur fractures.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Traditional fluoroscopy
Description: For patients in the control group, traditional fluoroscopy will be utilized for placement of the cephalomedullary nail.
Study: NCT05932121

Intervention type: PROCEDURE
Intervention: Thyroid lobectomy via trans-axillary approach
Description: Patient with PTC underwent thyroid lobectomy via trans-axillary approach

Intervention type: PROCEDURE
Intervention: Thyroid lobectomy via open approach
Description: Patient with PTC underwent thyroid lobectomy via open approach
Study: NCT05577364

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Selinexor: 40mg qw po, and 60mg qw po (phase Ib); RP2D (II study);~Selinexor is added from the second cycle of R-CHOP regimen.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: R-CHOP Protocol
Description: Rituximab: 375mg/m2 iv.drip D1;~Cyclophosphamide: 750mg/m2 iv.drip D1;~Doxorubicin: 50mg/m2 iv.drip D1;~Vincristine: 1.4g/m2 iv D1;~Prednisone: 100mg po D1-5;
Study: NCT04770259

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Timely pre-surgical conditioning
Description: Timely pre-surgical conditioning seeks to prepare frail, pre-frail and / or dependent older patients for the surgery process. For which a work plan has been designed according to your needs and health conditions.
Study: NCT06202313

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: Participants receive Cadonilimab 10mg/kg IV on Day 1 of each 21-day cycle PLUS Eribulin 1.4mg/m\^2 IV on Days 1 and 8 of each 21-day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eribulin
Description: Participants receive Eribulin 1.4mg/m\^2 IV on Days 1 and 8 of each 21-day cycle.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Eribulin
Description: Participants receive Eribulin 1.4mg/m\^2 IV on Days 1 and 8 of each 21-day cycle.
Study: NCT05819268

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ReACT
Description: ReACT includes 12 sessions with a therapist that will discuss a plan for managing FS.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CATCH-IT
Description: CATCH-IT involves the parent and child completing CBT modules on the web-based CATCH-IT platform, and they will meet with a CATCH-IT coach 12 times to discuss the modules and plan how to apply this to their life and their FS.
Study: NCT04665921

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SGN-STNV
Description: Given into the vein (IV; intravenously)
Study: NCT06633978

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MediTrain
Description: Participants will engage with a digital meditation app for 30m/day for 6wks. MediTrain is a tablet-based, meditation-inspired, cognitive training game aimed at improving self-regulation of internal attention and distractions. It was developed in collaboration with meditation thought-leader Jack Kornfield, and Zynga, a world-class video game company. It was created to make benefits of concentrative meditation more easily accessible to anyone, including complete novices. This is achieved by creating a game that yields quantifiable and attainable goals, provides feedback, and includes an adaptive algorithm to gradually increase difficulty as users improve.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wrist worn multi-sensor watches
Description: Stress and sleep data will be recorded at home throughout the intervention using FDA-approved wrist worn multi-sensor watches.
Study: NCT04787198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hypertonic saline
Description: The site of injections will be determined by palpation of the contracted First Dorsal Interosseus (FDI) muscle. The skin will be cleaned with alcohol before injection. A bolus injection of hypertonic saline (7% NaCl) will be administered to the FDI muscle using a 1 mL syringe with a disposable needle (27G), and 30 the volume of the bolus will be 0.2 mL .

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: isotonic saline
Description: The site of injections will be determined by palpation of the contracted First Dorsal Interosseus (FDI) muscle. The skin will be cleaned with alcohol before injection. A bolus injection of 0.2 mL isotonic saline (9 mg/mL) will be administered to the FDI muscle as control.
Study: NCT04730830

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire
Description: Patients completing emergence assessment questionnaires at the time of the first dressing placement, as well as at the scheduled weekly placement. As part of a planned repair, the emergence will be assessed at most once a week, preferably at the beginning of the week by the patient. In any other case of dressing change, an emergence assessment will be requested.
Study: NCT06633978

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sleep monitor
Description: Sleep Profiler devices are FDA-cleared reduced-montage EEG recording devices that will be used in accordance with its FDA clearance. They are completely non-invasive and are designed to be comfortable enough to wear all night without interfering with normal sleep. These devices enable quality sleep recordings in the comfort of people's homes, rather than required an overnight stay at a sleep lab at UCSF.
Study: NCT05254457

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: EN3835
Description: Treatment or retreatment with up to two doses of EN3835
Study: NCT06421402

Intervention type: OTHER
Intervention: Air quality monitoring at patient's home
Description: Indoor Air Quality:~- MICA-INBIOT system: temperature (ºC), humidity (%), CO2 (ppm), total Volatile Organic Ccompounds (VOCs) (ppb), Formaldehyde (µg/m3); and Particulate Matter (PM) 1/2.5/4/10 (µg/m3)~Outdoor Air Quality:~- Aeris Weather platform: NO, NO2, NOx, SO2, SO3, CO, and PM10, all expressed in µg/m3
Study: NCT06633380

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Physical Activity - Fasted
Description: 30 minutes of walking at a self-selected pace that they must have completed 15 minutes prior to consumption of first meal in the morning.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Physical Activity - Post-Meal
Description: 30 minutes of walking at a self-selected pace to start 30 minutes after the start of the first meal in the morning.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dispersed Physical Activity
Description: 10 minutes of walking at a self-selected pace to start 30 minutes after the start of each main meal throughout the day (i.e., three bouts total).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Snacks
Description: 2 minutes of walking or marching on the spot at a self-selected pace every 30 minutes throughout the day for 7.5 waking hours.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Muscle Strengthening
Description: 30 minutes of muscle strengthening exercises targeting the major muscle groups of the whole body, to start 30 minutes after the start of the first meal in the morning.
Study: NCT06421402

Intervention type: OTHER
Intervention: Questionnaires: Baseline & every six months
Description: General surveys:~* PROMs: ICHOM Adult Set; encompassing Patient Reported Outcomes Measurement Information System (PROMIS 10), World Health Organization Wellbeing Index (WHO 5) and World Health Organization Disability Assessment Schedule (WHO-DAS 12) questionnaires.~* PREMs: Patient-Reported Indicator Survey (PaRIS)~Disease specific questionaires:~* COPD: COPD Assessment Test (CAT); modified Medical Research Council (mMRC) Dyspnea scale.~* Asthma: Asthma Control Test (ACT); Test of Adherence to Inhalers (TAI-12); Asthma Quality of Life Questionnaire (mini AQLQ); Sino-Nasal Outcome Test (SNOT-22).

Intervention type: DIAGNOSTIC_TEST
Intervention: Lung function Testing: Baseline & every six months & during exacerbations
Description: * Forced Spirometry: Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1 second (FEV1)~* Forced Oscillation Technique: Impedance, resistance and reactance.~Ancillary measurements: Systemic arterial pressure and pulse oximetry.

Intervention type: OTHER
Intervention: EMR & registry data
Description: Electronic Medical Records (EMRs): Updated every twelve months to track clinical events from Hospital and Primary Care databases.~Registry data: from the Catalan Health Surveillance System (CHSS).

Intervention type: OTHER
Intervention: EMR & registry data
Description: Electronic Medical Records (EMRs): Updated every twelve months to track clinical events from Hospital and Primary Care databases.~Registry data: from the Catalan Health Surveillance System (CHSS).

Intervention type: DEVICE
Intervention: Communication channel - Health Circuit Mobile App (Herranz C. JMIR 2023)
Description: Health Circuit: chat, short questionnaires (Likert scale). As needed.

Intervention type: DEVICE
Intervention: Physiological data - Beat One Watch
Description: Enhanced with real-time physiological data tracking (heart rate, steps walked and Heart Rate Variability (HRV))

Intervention type: DEVICE
Intervention: Patient Empowerment
Description: Mobile App Health Circuit: follow-up of the personalized action plan agreed with the patient \& reference doctor
Study: NCT05488873

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: WST-057 Active
Description: WST-057 Topical Solution

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching Placebo Topical Solution
Study: NCT06421402

Intervention type: OTHER
Intervention: Characteristics of exacerbations
Description: Health Circuit: home-based oscillometry, daily disease-specific questionnaire during the acute episode and continuous assessment of physiological variables.
Study: NCT05185895

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: 15 minutes eccentric cycling
Description: The exposure to eccentric exercise will be individualized-intensity stepwise incremental cycle exercise starting at 50 Watt with individually tailored increments every 5 minutes.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 15 minutes eccentric cycling
Description: The exposure to eccentric exercise will be individualized-intensity stepwise incremental cycle exercise starting at 50 Watt with individually tailored increments every 5 minutes.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: 15 minutes concentric (normal) cycling
Description: The exposure to concentric exercise will be individualized-intensity stepwise incremental cycle exercise starting at 50 Watt with individually tailored increments every 5 minutes.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 15 minutes concentric (normal) cycling
Description: The exposure to concentric exercise will be individualized-intensity stepwise incremental cycle exercise starting at 50 Watt with individually tailored increments every 5 minutes.
Study: NCT04643119

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medial Congruent Insert
Description: The Medial Congruent Bearing (MC Bearing) design was introduced in 2016 for use with the Zimmer-Persona Cruciate-Retaining Femur: the design facilitates greater stability through increased anterior lip height compared to the original Cruciate Retaining Bearing (CR Bearing), allowing for greater anterior constraint and subluxation resistance that aids in full extension and deep flexion. Furthermore, the MC Bearing has been suggested for use in patients presenting with more complicated surgical histories (e.g prior high tibial osteotomies or patellectomies), whereas the original CR Bearing is strictly suggested for use only in patients undergoing knee surgery for the first time, where the posterior cruciate ligament may still be intact.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cruciate-Retaining Insert
Description: The Cruciate-Retaining Bearing (CR Bearing) design was launched together with the use of the Cruciate-Retaining Femoral Components (CR Femur) of the Zimmer-Biomet Persona® Total Knee system. The design not only stabilises the knee through medial conformity and anterior constraint, but also allows for freer and more natural deep flexion through freer movement of the lateral condyle.
Study: NCT05531721

Intervention type: OTHER
Intervention: Observation
Description: Observation and retrospective data collection
Study: NCT05363865

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Community Intervention
Description: Modules of community building, HIV/HCV prevention, drug and service stigma, identification of mental health problems

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: health websites and county information provided to participants
Study: NCT05394480

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood pressure (Systolic, Diastolic), Pulse value, O2 saturations were measured.
Description: Salivary cortisol was measured by electrochemiluminescence (ECLIA) method using the Cobas Cortisol ll kit.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood pressure (Systolic, Diastolic), Pulse value, O2 saturations were measured.
Description: Salivary cortisol was measured by electrochemiluminescence (ECLIA) method using the Cobas Cortisol ll kit.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood pressure (Systolic, Diastolic), Pulse value, O2 saturations were measured.
Description: Salivary cortisol was measured by electrochemiluminescence (ECLIA) method using the Cobas Cortisol ll kit.
Study: NCT05079399

Intervention type: OTHER
Intervention: Blood draw
Description: Blood samples will be collected via venipuncture

Intervention type: OTHER
Intervention: Blood draw
Description: Blood samples will be collected via venipuncture

Intervention type: OTHER
Intervention: Blood draw
Description: Blood samples will be collected via venipuncture

Intervention type: OTHER
Intervention: Blood draw
Description: Blood samples will be collected via venipuncture

Intervention type: OTHER
Intervention: Blood draw
Description: Blood samples will be collected via venipuncture

Intervention type: OTHER
Intervention: Blood draw
Description: Blood samples will be collected via venipuncture
Study: NCT05841199

Intervention type: DIAGNOSTIC_TEST
Intervention: Pressure and flow measurement during simulated VT
Description: Participants undergoing coronary angiography will have measurements of blood pressure, coronary pressure and coronary flow during simulated VT. VT will be simulated using pacing at a range of heart rates.

Intervention type: DIAGNOSTIC_TEST
Intervention: Pressure and flow measurement during simulated VT
Description: Participants undergoing coronary angiography will have measurements of blood pressure, coronary pressure and coronary flow during simulated VT. VT will be simulated using pacing at a range of heart rates.

Intervention type: DIAGNOSTIC_TEST
Intervention: Pressure and flow measurement during simulated VT
Description: Participants undergoing coronary angiography will have measurements of blood pressure, coronary pressure and coronary flow during simulated VT. VT will be simulated using pacing at a range of heart rates.

Intervention type: DIAGNOSTIC_TEST
Intervention: Pressure and flow measurement during simulated VT
Description: Participants undergoing coronary angiography will have measurements of blood pressure, coronary pressure and coronary flow during simulated VT. VT will be simulated using pacing at a range of heart rates.
Study: NCT05928611

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Inferior alveolar nerve block with dexamethasone
Description: Using articaine for inferior alveolar block with intraligmentary dexamethasone

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Buccal infiltratation with dexamethasone
Description: Using articaine for buccal infiltratation with intraligmentary dexamethasone

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Inferior alveolar nerve block
Description: Using articaine for injection
Study: NCT04878679

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strenght training combined with WB-EMS
Description: Bodyweight exercise training combined with WB-EMS (2 times/week) with a 85Hz electrical impulse

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cardiovascular training with WB-EMS
Description: Cardiovascular training , using the rowing machine, combined with WB-EMS (2 times/week) with a 7Hz electrical impulse

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: No physical activity
Study: NCT05823012

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: levothyroxine sodium
Description: Levothyroxine sodium 10 mg/mL
Study: NCT06021626

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CRD3874
Description: Starting dose is 0.1 mg/kg for weekly IV infusion of CRD3874-SI.~Cohort CRD3874-SI Dose level (mg/kg)~1. 0.1~2. 0.3~3. 0.9~4. 1.8~5. 2.7~6. 4.05
Study: NCT06633094

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational videos
Description: Internet will be used to deliver educational videos to subjects enrolled in the home management arm of the study which will be available on the Carilion Clinic Orthopaedic Education YouTube Channel. This will consist of a prerecorded video made by the three pediatric orthopaedic surgeons on this study explaining the nature of buckle fractures and treatment. Participants will be sent a link to the video over email (an example of a similar video in clinical use at Carilion Orthopaedics and the script of the video can be found in the study document attached).
Study: NCT06633289

Intervention type: OTHER
Group type: OTHER
Intervention: Experimental formula
Description: New hydrolyzed rice protein-based formula

Intervention type: OTHER
Group type: OTHER
Intervention: Experimental formula
Description: New hydrolyzed rice protein-based formula

Intervention type: OTHER
Group type: OTHER
Intervention: Control formula
Description: Commercially available amino acid-based formula.

Intervention type: OTHER
Group type: OTHER
Intervention: Control formula
Description: Commercially available amino acid-based formula.
Study: NCT05972330

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: VRx MyBiotics Oral Lozenges
Description: VRx MyBiotics Oral Lozenges are composed of prebiotics, probiotics, and postbiotics.
Study: NCT05705076

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: catheter induced thromboprophylaxis
Description: Direct oral anticoagulation for catheter induced thromboprophylaxis

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: catheter induced thromboprophylaxis
Description: Direct oral anticoagulation for catheter induced thromboprophylaxis
Study: NCT05891028

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-EB-ss-CPT
Description: 68Ga-EB-ss-CPT were intravenous injected into the patients before PET/CT scans

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 64Cu-EB-ss-CPT
Description: 64Cu-EB-ss-CPT were intravenous injected into the patients before PET/CT scans
Study: NCT05102227

Intervention type: DEVICE
Intervention: Left bundle branch area pacing
Description: A dual-chamber DF-1 defibrillator is implanted. Left bundle branch area pacing is performed for cardiac resynchronization therapy.