TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05421234

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: diagnostic test and sperm analysis
Description: Diagnostic Test: 2x14 ml of peripheral blood collected in the tube with anticoagulant, for platelet isolation, respirometry mitochondrial analysis, antioxidants (coenzyme Q10, vitamin E, gamma-tocopherol, beta-carotene) and TBARS estimation.~Sperm analysis: standard spermiogram examination (volume, pH, number, motility and pathology) in the broker chamber, as well as extended examinations: mioxsys for redox potential, Vitalsperm (eosin-nigrosine staining) for sperm vitality and anti-sperm antibody (IgG) test.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: diagnostic test and sperm analysis
Description: Diagnostic Test: 2x14 ml of peripheral blood collected in the tube with anticoagulant, for platelet isolation, respirometry mitochondrial analysis, antioxidants (coenzyme Q10, vitamin E, gamma-tocopherol, beta-carotene) and TBARS estimation.~Sperm analysis: standard spermiogram examination (volume, pH, number, motility and pathology) in the broker chamber, as well as extended examinations: mioxsys for redox potential, Vitalsperm (eosin-nigrosine staining) for sperm vitality and anti-sperm antibody (IgG) test.
Study: NCT05897840

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fiber-optic probe CeVOX
Description: Installation of the fiber-optic probe within the existing central venous catheter for continuous monitoring of SvcO2
Study: NCT06266949

Intervention type: DIAGNOSTIC_TEST
Intervention: SONDA
Description: Perimetry based visualfield analysis

Intervention type: DIAGNOSTIC_TEST
Intervention: SONDA
Description: Perimetry based visualfield analysis
Study: NCT06604546

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hyaluronidase
Description: 150 IU group D1:150 IU hyaluronidase+500 ml Lactated Ringer's (LR)(Subject's left or right leg)； D2:150 IU hyaluronidase+250 ml Lactated Ringe's (LR)(Subject's left or right arm)； D3:150 IU hyaluronidase+500 ml Normal Saline (NS)(subject's left or right leg)； D4:150 IU hyaluronidase+1000 ml Lactated Ringer's (LR)(Subject's back)； 385 IU group D1:385 IU hyaluronidase+250 ml Lactated Ringer's (LR)(Subject's left or right arm)； 1500 IU group D1:1500 IU hyaluronidase+250 ml Lactated Ringer's (LR)(Subject's left or right arm).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 150 IU group D1:Placebo+500 ml Lactated Ringer's (LR)(Subject's left or right leg)； D2:Placeboe+250 ml Lactated Ringer's (LR)(Subject's left or right arm)； D3:Placebo+500 ml Normal Saline (NS)(Subject's left or right leg)； 385 IU group D1:Placebo+250 ml Lactated Ringer's (LR)(Subject's left or right arm)； 1500 IU group D1:Placebo+250 ml Lactated Ringe's (LR)(Subject's left or right arm).
Study: NCT06599710

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: AndoSanTM
Description: Fermented water-based exctract of Agaricus subrufesence, Hericum erinacus, and Grifola frondosa
Study: NCT04986046

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home Plate Lite
Description: Home Plate Lite comprises electronic educational content (e.g. recipes, instructional videos) disbursed at least weekly.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Home Plate
Description: Virtual Home Plate comprises two, 45-minute weekly sessions where parents work together with a study staff member to discuss the themes and prepare the components of a meal, including entrees, side dishes, and desserts.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fruit and Vegetable prescription
Description: All families will receive FVRx over two months; FVRx can be redeemed for fresh, frozen, or canned produce at participating retailers in Philadelphia

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fruit and Vegetable prescription
Description: All families will receive FVRx over two months; FVRx can be redeemed for fresh, frozen, or canned produce at participating retailers in Philadelphia

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fruit and Vegetable prescription
Description: All families will receive FVRx over two months; FVRx can be redeemed for fresh, frozen, or canned produce at participating retailers in Philadelphia
Study: NCT06605443

Intervention type: DEVICE
Intervention: Breath analyzer
Description: The study subject will be advised to sit quietly for minimum 10 minutes prior the sampling to avoid temporal changes in levels of volatile organic compunds (VOCs) related to body movement or try to avoid abrupt changes in body posture. Then, he/she will be asked to blow in the breath analyzer in order to obtain the exhaled VOCs profile.

Intervention type: DEVICE
Intervention: Breath analyzer
Description: The study subject will be advised to sit quietly for minimum 10 minutes prior the sampling to avoid temporal changes in levels of volatile organic compunds (VOCs) related to body movement or try to avoid abrupt changes in body posture. Then, he/she will be asked to blow in the breath analyzer in order to obtain the exhaled VOCs profile.

Intervention type: DEVICE
Intervention: Skin patch
Description: A skin patch will be placed in the anterior part of the patient\&#39;s arm for the obtention of the skin VOCs profile (estimated sampling time of around 1 h). These profiles will be recorded with a dedicated software and analyzed using standard statistical methods.

Intervention type: DEVICE
Intervention: Skin patch
Description: A skin patch will be placed in the anterior part of the patient\&#39;s arm for the obtention of the skin VOCs profile (estimated sampling time of around 1 h). These profiles will be recorded with a dedicated software and analyzed using standard statistical methods.

Intervention type: GENETIC
Intervention: Liquid biopsy
Description: Circulating free tumor DNA (cfDNA) will be extracted from patient\&#39;s blood and analyzed to detect mutations in BRAF and other prognostic genes.

Intervention type: GENETIC
Intervention: Liquid biopsy
Description: Circulating free tumor DNA (cfDNA) will be extracted from patient\&#39;s blood and analyzed to detect mutations in BRAF and other prognostic genes.
Study: NCT06600633

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: 14 days of intervention with Placebo Product (PP)
Description: 1 spray (0 mg melatonin)

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: 14 days of intervention with Active Control (AC)
Description: 1 spray (1 mg melatonin)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 14 days of intervention with Test Product (TP)
Description: 1 spray (0.3 mg melatonin)
Study: NCT06601868

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: R-Support Prepare & After nutritional supplement
Description: R-Support is a nutritional supplement containing proteins, Vitamine A, Vitamine B6, Vitamine B11, Vitamine B12, Vitamine C, Vitamine D3, Vitamine E, IJzer, Koper, Selenium, Zink, Magnesium, Omega-3 and Beta-glucanen.
Study: NCT06598072

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mouthwash CPC+Zn+F
Description: A mouthwash containing CPC + Zn and fluoride

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Essential oils mouthwash
Description: Essential oils mouthwash

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dental floss
Description: Dental Floss
Study: NCT06605755

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Different immunization regiments with DTaP-IPV/Hib Pentavalent Vaccine
Description: The test vaccine in this study was Pentaxim®, a pentavalent vaccine produced by Sanofi Pasteur, France.This vaccine is a combination vaccine consisting of adsorbed acellular DTP and inactivated polio vaccine (DTaP-IPV) and Haemophilus influenzae type b conjugate vaccine (Hib).~1. Intervention group: 1 dose of experimental vaccine at 2, 4 and 6 months of age, and 1 dose of enhanced vaccine at 18 months of age.~2. Control group: 1 dose of experimental vaccine at 2, 3 and 4 months of age, and 1 dose of enhanced vaccine at 18 months of age.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Different immunization regiments with DTaP-IPV/Hib Pentavalent Vaccine
Description: The test vaccine in this study was Pentaxim®, a pentavalent vaccine produced by Sanofi Pasteur, France.This vaccine is a combination vaccine consisting of adsorbed acellular DTP and inactivated polio vaccine (DTaP-IPV) and Haemophilus influenzae type b conjugate vaccine (Hib).~1. Intervention group: 1 dose of experimental vaccine at 2, 4 and 6 months of age, and 1 dose of enhanced vaccine at 18 months of age.~2. Control group: 1 dose of experimental vaccine at 2, 3 and 4 months of age, and 1 dose of enhanced vaccine at 18 months of age.
Study: NCT06606236

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: H2O2 at 35% for 8 minutes
Description: The investigators rigorously followed the manufacturer's instructions for all bleaching systems.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: H2O2 at 40% for 20 minutes
Description: The investigators rigorously followed the manufacturer's instructions for all bleaching systems.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: H2O2 at 25% plus cold blue light for 15 minutes
Description: The investigators rigorously followed the manufacturer's instructions for all bleaching systems.
Study: NCT06605144

Intervention type: OTHER
Group type: OTHER
Intervention: 1- Vasopressors - Mean arterial pressure 55-59
Description: Vasopressors will be titrated according to 55-59 range.

Intervention type: OTHER
Group type: OTHER
Intervention: 2- Vasopressors - Mean arterial pressure 60-65
Description: Vasopressors will be titrated according to 60-65 range.

Intervention type: OTHER
Group type: OTHER
Intervention: 3- Vasopressors - Mean arterial pressure 66-69
Description: Vasopressors will be titrated according to 66-69 range.

Intervention type: OTHER
Group type: OTHER
Intervention: 4- Vasopressors - Mean arterial pressure 70-75
Description: Vasopressors will be titrated according to 70-75 range.
Study: NCT06661486

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Uniformed intervention group
Description: The investigators provide lifestyle intervention through a health education programme which is in a group setting. The sessions consisted of short talks on a health-related topic targeting lifestyle factors associated with dementia risk, followed by group activities that required interactions, cognitive engagement, and the acquisition of certain skills (for example, how to read food labels, how to measure blood pressure, how to recognize signs of depression, et al).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Individualised intervention group
Description: On top of the uniformed intervention group, the individualised intervention group receives also 1:1 sessions every 3 months within 2 years. Participants will review the knowledge taught in the group sessions individually and the investigator will address the participant's concerns and provide advice to the participant for a better lifestyle accordingly.
Study: NCT04326478

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Enrolled children in the placebo arm of this study will receive a single dose of non-antibiotic placebo administered by a trained study nurse within 12 hours of a member of their household testing positive for cholera.
Study: NCT06272188

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: web-based online preconceptional counselling
Description: web-based online preconceptional counselling
Study: NCT05314049

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mckenzie Extension Protocol
Description: Mckenzie Extension Exercise Protocol will be performed by participants in prone position

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mckenzie Extension Protocol
Description: Mckenzie Extension Exercise Protocol will be performed by participants in prone position

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lumbar SNAGs
Description: Lumbar SNAGs will be performed in lumbar flexion and extension in standing Position

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: inferential therapy
Description: 4 pole inferential therapy in combination with superficial heating for 20 minutes

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: inferential therapy
Description: 4 pole inferential therapy in combination with superficial heating for 20 minutes

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Heat Therapy
Description: superficial heating for 20 minutes

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Heat Therapy
Description: superficial heating for 20 minutes
Study: NCT05856656

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music therapy
Description: Music therapy is a technique of care, accompaniment and support, which aims to improve health and well-being.
Study: NCT05851014

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GB491 combined with Letrozole
Description: Patients were randomized to receive GB491 150 mg orally twice daily, depending on their assignment. Letrozole 2.5 mg orally once a day from the first day of cycle 1 (one cycle every 28 days)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo combined with Letrozole
Description: Patients were randomized to receive placebo orally twice daily, depending on their assignment. Letrozole 2.5 mg orally once a day from the first day of cycle 1 (one cycle every 28 days)
Study: NCT06452173

Intervention type: DIAGNOSTIC_TEST
Intervention: Plasma
Description: Plasma levels of metabolites and some proteins will be further determined

Intervention type: DIAGNOSTIC_TEST
Intervention: Plasma
Description: Plasma levels of metabolites and some proteins will be further determined

Intervention type: DIAGNOSTIC_TEST
Intervention: carotid high-resolution magnetic resonance imaging
Description: Define plaque composition and morphological characteristics

Intervention type: DIAGNOSTIC_TEST
Intervention: carotid high-resolution magnetic resonance imaging
Description: Define plaque composition and morphological characteristics
Study: NCT06298266

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: infusion of GPRC5D-CD19 CAR T injection
Description: Infusion of GPRC5D-CD19 CAR T cells injection by dose of 1.0×10\^6 /kg±20 % CAR-T ，3.0×10\^6 /kg±20%、6.0×10\^6 /kg±20%. Administration method: intravenous infusion. Subjects will be treated with Fludarabine and Cyclophosphamide before cell infusion.
Study: NCT05153070

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporin
Description: • Ciclosporin: 3.5mg/kg, twice a day, oral, between Day 1 and Day 60

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cyclosporin
Description: • Ciclosporin: 3.5mg/kg, twice a day, oral, between Day 1 and Day 60

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ILT101
Description: • ILT-101: 1MIU/day in a volume of 1 ml; subcutaneous injection every day during 5 consecutive days and then every week between Day 63 and Day 354.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: • Placebo with an identical formulation and regimen of injections i.e. Subcutaneous injection every day (5 consecutive days) then then every week between Day 63 and Day 354.
Study: NCT06605482

Intervention type: OTHER
Intervention: Patient Reported Outcome Measures
Description: Participants will complete the following outcome measures American Shoulder and Elbow Surgeons Evaluation Questionnaire - upper limb function score 12-Item Short Form Survey - general health questionnaire

Intervention type: OTHER
Intervention: Patient Reported Outcome Measures
Description: Participants will complete the following outcome measures American Shoulder and Elbow Surgeons Evaluation Questionnaire - upper limb function score 12-Item Short Form Survey - general health questionnaire

Intervention type: OTHER
Intervention: Range of Motion
Description: Shoulder and Elbow Range of Motion collected at the time of radiographic union

Intervention type: OTHER
Intervention: Range of Motion
Description: Shoulder and Elbow Range of Motion collected at the time of radiographic union
Study: NCT06604845

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group cognitive behavioural therapy (CBT)
Description: CBT based on Safren's manual CBT for ADHD/Mastering Your Adult ADHD20 adapted for group format. The program includes psychoeducation and cognitive restructuring and aims to improve ADHD symptoms, especially planning, organisation, attention and adaptive thinking. The CBT groups will meet at the clinic weekly for 12 weeks for 2 hours including a break in the middle. The groups are led by two clinicians.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Activity group
Description: The Activity group is a structured manualised group intervention designed for this and planned future studies of psychosocial treatments for adults with ADHD and/or autism. The program includes group discussions, peer-sharing and social every-day life activities. The Activity groups will meet at the clinic weekly for 12 weeks for 2 hours including a break in the middle. The groups are led by two trainers.
Study: NCT06602388

Intervention type: OTHER
Intervention: Biological sampling
Description: Collection of biological samples from healthy volunteers: Stool, urine, saliva, buccal swab, nasal swab, superficial skin swab, hair
Study: NCT06606977

Intervention type: OTHER
Intervention: Training
Description: During the detraining period, the athletes did not follow any external (personal) trainer-supported training program and their diet was not altered. Athletes have reported that they have stayed at home as a necessity of the Covid-19 pandemic process, and have done simple home exercises, walking and jogging exercises in a limited way during this time.~The training period included the standard wrestling trainings, which were determined by the national team coaches and realized at different intensities, during the 8 weeks when the training started. Following the period of detraining the level of training intensity was progressively increased throughout the initial 5 weeks. In the 6th and 7th week, training intensity peaked . In the 8th week prior to the competition, the training intensity was reduced in order to prepare and recover for the following competition. After the training period, the wrestlers participated in an international competition.
Study: NCT06590129

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hydrodissection of median nerve
Description: Ultrasound guided hydrodissection of median nerve in carpal tunnel with 5% dextrose solution

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy
Description: 5-20 sessions in rehabilitation area with physical media: paraffin glove (10 coats for 15min), mobilizations of wrist and fingers, strectching of wrist and fingers tendons/muscles, muscle stregthening whit isometric or isotonic excercises to intrinsic muscles of the hand an forearm, and occupational therapy with techniques for sensory return, nerve and tendon sliding techniques, activities aimed at improving basic hand functions and work simulation activities.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy
Description: 5-20 sessions in rehabilitation area with physical media: paraffin glove (10 coats for 15min), mobilizations of wrist and fingers, strectching of wrist and fingers tendons/muscles, muscle stregthening whit isometric or isotonic excercises to intrinsic muscles of the hand an forearm, and occupational therapy with techniques for sensory return, nerve and tendon sliding techniques, activities aimed at improving basic hand functions and work simulation activities.
Study: NCT06110715

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: theta tACS stimulation
Description: The low intensity transcranial electrical stimulation will be administered with a battery-powered, current-controlled, multi-channel stimulator from Neuroelectrics® Starstim 8. This device comes with a neoprene headcap to hold the electrodes in place. TACS will be delivered concurrently with the task. The multichannel, current-driven stimulator (Neuroelectrics StarStim 8) will be used to control independent stimulation electrodes on the scalp of the volunteer. The stimulation intensity will be up to 2 mA.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: sham tACS stimulation
Description: A placebo control stimulation will use an identical montage to the stimulation montage. However, polarities of the electrodes will be such that only a minimal amount of current reaches the brain, which is achieved through controlled current shunting between neighboring electrodes. This so-called ActiSham protocol is a verified method to imitate the sensations of actual tACS, with minimal stimulation of the brain .
Study: NCT06135896

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tripegfilgrastim
Description: Tripegfilgrastim to reduce the risk of severe neutropenia in patients with unresectable pancreaticobiliary cancers
Study: NCT06608134

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Umbilical Cord Wharton's Jelly Allograft Intra-articular Knee Injection
Description: Direct injection of biologic into the knee joint.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Umbilical Cord Wharton's Jelly Allograft Intra-articular Knee Injection
Description: Direct injection of biologic into the knee joint.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Umbilical Cord Wharton's Jelly Allograft Intra-articular Knee Injection
Description: Direct injection of biologic into the knee joint.
Study: NCT06669780

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AMMO PTH DTx
Description: An online cognitive behavioral therapy program accessed through a online program.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: AMMO SHAM
Description: Online activities not including CBT in the AMMO online program.
Study: NCT06606795

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation
Description: For the treatment to be applied in the SMT group, segmental dysfunctions will be determined using static and dynamic palpation techniques and the applications will be applied with a chiropractic method, high-speed, low-amplitude spinal manipulation method, at the level of the dysfunctional spine.
Study: NCT06679101

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin
Description: Belantamab mafodotin will be administered.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide will be administered.
Study: NCT05673551

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR-PAT
Description: Smartphone-based Virtual Reality Pain Alleviation Tool (VR-PAT) via a lightweight, mobile VR headset
Study: NCT06466759

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mc Grath Videolaryngoscope
Description: Use of Videolaryngoscope with Mc Grath versus direct laryngoscopy
Study: NCT04886674

Intervention type: DIETARY_SUPPLEMENT
Intervention: bovine colostrum
Description: The neonates will receive the colostrum in a dose of 2 g/dose for the 1000-1500 g stratum and 1.2 g/dose for \< 1000 g stratum, four times a day until discharge or death or day 21 of life, whichever is earlier.