TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04562688

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CICADAS and then PEERS
Description: Participants will complete sensory processing assessments and neuroplasticity-based social cognitive training (NB-SCT) exercises on a digital device for a total of 40 hours. The CICADAS app captures user-specific sensory processing abnormalities (SPA) through 10 brief computerized assessments. The data from these assessments guide and personalize the delivery of 10 NB-SCT exercises. After 16 weeks, participants will then crossover to PEERS, participants will be asked to attend weekly 1-hour group sessions led by a PEERS clinician. Each PEERS group session will consist of a minimum of 3 participants and will meet as a group using Zoom. PEERS teaches how to solve real-life social dilemmas, appraise affect and social contexts, and initiate and maintain conversations while receiving feedback from peers and clinicians.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEERS + CICADAS and then no-contact
Description: Participants will complete both PEERS and CICADAS study activities. Participants will complete sensory processing assessments and neuroplasticity-based social cognitive training (NB-SCT) exercises on a digital device for a total of 40 hours. The CICADAS app captures user-specific sensory processing abnormalities (SPA) through 10 brief computerized assessments. The data from these assessments guide and personalize the delivery of 10 NB-SCT exercises. In addition, participants will be asked to attend weekly 1-hour group sessions led by a PEERS clinician. Each PEERS group session will consist of a minimum of 3 participants and will meet as a group using Zoom. PEERS teaches how to solve real-life social dilemmas, appraise affect and social contexts, and initiate and maintain conversations while receiving feedback from peers and clinicians. After 16 weeks, participant will crossover to No-Contact with no active intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEERS + Active Comparator and then no-contact
Description: Participants will complete both PEERS and Active Comparator study activities. Participants will engage in computerized, casual video games for a total of 40 hours. Participants will also complete the 10 sensory processing abnormalities (SPA) computerized assessments. In addition, participants will be asked to attend weekly 1-hour group sessions led by a PEERS clinician. Each PEERS group session will consist of a minimum of 3 participants and will meet as a group using Zoom. PEERS teaches how to solve real-life social dilemmas, appraise affect and social contexts, and initiate and maintain conversations while receiving feedback from peers and clinicians. After 16 weeks, participant will crossover to No-Contact with no active intervention.
Study: NCT05058820

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post Facilitation stretch
Description: Hot pack 10 mins/ 1set/ (3 days/ week), TENS 10 mins/ 1 set/ (3 days/ week), Post facilitation stretch 15 secs isometric hold/ 15 secs stretch/ 30 secs relax/ 5 reps/ 1 set/ (3 days/ week), Deep friction massage 5 minutes/ (3 days/ week). A total of 6 weeks (18 sessions, 3 days/ week) were given each consisting of 30 mins.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Isolated Stretching
Description: Hot pack 10 mins/ 1set/ (3 days/ week), TENS 10 mins/ 1 set/ (3 days/ week), Active Isolated Stretching 2 secs hold/ 10 reps/ 1 set/ (3 days/ week), Deep friction massage 5 minutes/ (3 days/ week). A total of 6 weeks (18 sessions, 3 days/ week) were given each consisting of 30 mins.
Study: NCT05406778

Intervention type: DEVICE
Group type: OTHER
Intervention: SPARK Test
Description: Twenty (20) minutes of resting state EEG data collection.
Study: NCT03970057

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-based Cognitive Behavioural Therapy
Description: MoodUP is an iCBT intervention that is tailored to perinatal women. The core content is presented via different types of devices, such as smartphones, tablets, laptops, or desktops, connected to the internet. The program is designed as an integration of online sessions, self-monitoring, homework, peer support, and therapist support.~MoodUP consists of six online sessions focused on CBT skills for improving stress, anxiety, and depressive symptoms among at-risk antenatal women; each session takes between 30 and 40 minutes to complete. The content of the sessions will be as follows: Session 1: Managing mood, Session 2: Psychoeducation, Session 3: Cognitive restructuring, Session 4: Behavioural activation, Session5: Lifestyle modification, Session 6: Problem-solving.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: Participants will receive a series of six, weekly online sessions comprising general antenatal education. The content of the sessions will be as follows: Session 1: Parenthood; Session 2: Diet; Session 3: Exercise; Session 4: Breastfeeding; Session 5: Rest and sleep and Session 6: Common pregnancy problems.
Study: NCT06469970

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucose 30% Intravenous Solution
Description: Measurement of IDVG on admission, at 4 hours (H+4), and at 8, 16, 24, 48, 72 and 96 hours (H+8, H+16, H+24, H+48, H+72 and H+96) post-burn. The principle of this measurement consists of taking a reference blood glucose level measured on an arterial blood sample (arterial catheter) using a blood glucose meter. A bolus of 5g of glucose is injected into a central venous line over 30 seconds. A second blood glucose level is measured 3 minutes after the end of the injection.~The intra-thoracic blood volume (ITBV) and extra-vascular lung water (EVLW) are measured using the PiCCO device as part of the usual management of burn patients.
Study: NCT06750341

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QLC7401
Description: QLC7401 combined with lipid-lowering agents

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QLC7401
Description: QLC7401 combined with lipid-lowering agents

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QLC7401
Description: QLC7401 combined with lipid-lowering agents

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo combined with lipid-lowering agents
Study: NCT04925583

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy (SBRT)
Description: * level 0 (de-escalation): 10 x 5.0Gy~* level 1 (start): 10 x 5.5Gy~* level 2: 10 x 6.0Gy~* level 3: 10 x 6.5Gy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy (SBRT)
Description: * level 0 (de-escalation): 10 x 5.0Gy~* level 1 (start): 10 x 5.5Gy~* level 2: 10 x 6.0Gy~* level 3: 10 x 6.5Gy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy (SBRT)
Description: * level 0 (de-escalation): 10 x 5.0Gy~* level 1 (start): 10 x 5.5Gy~* level 2: 10 x 6.0Gy~* level 3: 10 x 6.5Gy

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy (SBRT)
Description: * level 0 (de-escalation): 10 x 5.0Gy~* level 1 (start): 10 x 5.5Gy~* level 2: 10 x 6.0Gy~* level 3: 10 x 6.5Gy
Study: NCT05560360

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR1459 tablet
Description: 100 mg/tablet; administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Efavirenz tablet
Description: 600 mg/tablet; administered orally
Study: NCT05027087

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Blueberry gummy
Description: Gummy bear containing blueberry powder

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo gummy
Description: Gummy bear with no active ingredients
Study: NCT05444179

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mommies can Eat & Exercise with No Stress (MomEENS)
Description: This intervention involving behaviour modification, incorporates nutrition and physical activity modification. The intervention encourages participants to consume a healthy diet and active lifestyle during postpartum period. For nutrition modification, a general advice on healthy nutrition were given and several nutrients are highlighted which evidenced can reduce postpartum depression. While for physical activity, the mothers are encouraged to do exercise, targeting aerobic, flexibility, and strength type of exercise. The exercise protocol is progressive. During the first month, the participants will be advised to conduct flexibility and strength exercises for 8 repetitions (1 set), at least 3 days per week for both aerobic and flexibility exercise. While during the second month, participants are asked to increase repetitions and frequency of exercises, up to 16 repetitions (2 set) for each flexibility exercise, and conduct exercise at least 5 days per week.
Study: NCT06341491

Intervention type: BEHAVIORAL
Intervention: Pé-de-Meia Program
Description: The Pé-de-Meia Program was established by the Brazilian Federal Government with the aim of encouraging the retention of low-income students in high school by providing maintenance scholarships and savings opportunities. To be eligible for the program, a young person must: Be properly enrolled in a regular public high school course, be between 14 to 24 years old, come from a low-income family, and be registered in the Bolsa Família Program. The Program offers four types of incentives:~An enrollment grant registered at the beginning of the academic year, paid once a year in the amount of 200 BRL.~A minimum school attendance of 80% of the total class hours, paid in nine installments throughout the year at 200 BRL each.~Proven participation in the National High School Exam (ENEM), paid once to the student enrolled in the third year of high school, in the amount of 200 BRL.~Completion of the high school academic years, paid in a single installment of 1,000 BRL.
Study: NCT05678569

Intervention type: DIAGNOSTIC_TEST
Intervention: Dual Energy Xray Absorptiometry
Description: DXA for diagnosis of osteoporosis
Study: NCT05747430

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IRX-101
Description: IRX-101 is a novel ocular anti-septic

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Providone-Iodine
Description: 5% Providone-Iodine
Study: NCT05866406

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time restricted eating
Description: Participants assigned to the TRE group will have to consume all their daily meals and snacks during a 9-hour window for 12 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Extended eating window
Description: Participants assigned to the control group will have to consume all their daily meals and snacks during a 14-hour window for 12 weeks.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy diet
Description: Participants will be provided nutrition education and counselling to follow a diet consistent with the existing guidelines for chronic disease prevention.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy diet
Description: Participants will be provided nutrition education and counselling to follow a diet consistent with the existing guidelines for chronic disease prevention.
Study: NCT06004362

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Complementary and Integrative Medicine online intervention, routine care and book
Description: The online program takes place in a multiprofessionally guided online group setting once a week for up to 180 minutes (including several breaks) over a period of 10 weeks:~* Basic principles of a plant-based whole-food nutrition~* Procedures of hydrotherapy according to Kneipp~* Self-help strategies (e.g. teas, wraps, compresses etc.)~* Methods of mind-body medicine (mindfulness, meditation, breathing, yoga etc.)~* Methods of extended Complementary and Integrative Medicine (e.g. acupressure)~It is recommended to practice a part of the taught exercises at home for about 30 minutes daily. In addition, the patients receive a book for the treatment of post-covid syndrome complaints. Group 1 additionally uses the already existing routine care (e.g. general practitioner).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine care and book
Description: Participants in the second study arm receive routine care, e.g. from their general practitioner. In addition, the patients receive the same book as group 1 for the treatment of post-covid syndrome complaints. The participants of the second study arm will be offered to participate in the Complementary and Integrative Medicine online intervention after 4 months within the study.
Study: NCT05514483

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single intravenous dose of 10 mL of sodium chloride (NaCl) 0.9% over 15 minutes.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ondansetron
Description: Single intravenous dose of ondansetron hydrochloride dihydrate 0.15 mg/kg (maximum 16 mg) in 10 mL of NaCl 0.9% over 15 minutes.
Study: NCT05613361

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colistin
Description: added for infection with multi drug resistant bacteria

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colistin
Description: added for infection with multi drug resistant bacteria

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Curcumin
Description: added for the possible nephroprotective effect
Study: NCT05868395

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Polatuzumab, bendamustin und rituximab
Description: * Polatuzumab vedotin 1.8 mg/kg i.v. on day 2 of cycle 1, then on day 1 of each subsequent cycle~* Bendamustine 90 mg/m2 i.v. day 2 \& 3 of cycle 1, then on day 1 \& 2 of each subsequent cycle~* Rituximab 375 mg/m2 i.v. on day 1 of each cycle~* Each cycle is 21 days long~* Up to 6 cycles per patients planned
Study: NCT06183177

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole-Body Vibration
Description: 10 minutes of whole-body vibration when performing semi-squatting or forward lunges (12-16 Hz, varying intensity from low to high depending on patients' tolerance

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Four to five sessions of a physiotherapist-led exercise program with education talk (20 minutes), group exercises (30 minutes) and individual exercises (30 minutes) per week supplemented with home exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Four to five sessions of a physiotherapist-led exercise program with education talk (20 minutes), group exercises (30 minutes) and individual exercises (30 minutes) per week supplemented with home exercises
Study: NCT05232175

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALT-BB4
Description: Recombinant Hyaluronidase

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALT-BB4
Description: Recombinant Hyaluronidase

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALT-BB4
Description: Recombinant Hyaluronidase

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9%NaCl
Description: Normal Saline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9%NaCl
Description: Normal Saline
Study: NCT04849754

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: bone scintigraphy
Description: Bone scintigraphy
Study: NCT05755438

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib Cream
Description: Ruxolitinib cream 1.5% twice daily (BID) during the vehicle controlled (DBVC)and open label treatment period (OLE).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: Ruxolitinib matching vehicle cream 1.5% twice daily (BID) during the vehicle controlled period (DBVC).
Study: NCT05792709

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral Motor Therapy
Description: In Traditional therapy we will give cognitive and articulation therapy to the patients.
Study: NCT05022771

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo to match

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PMG1015 Dose 7
Description: Dose level 7 of PMG1015
Study: NCT05722899

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Football training
Description: 10-week progressive football training with small-sided games, 2x/week, 45min-1h sessions
Study: NCT05792709

Intervention type: OTHER
Group type: OTHER
Intervention: Oral Motor Therapy
Description: In Traditional therapy we will give cognitive and articulation therapy to the patients.
Study: NCT05933148

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Siemens 7T MRI
Description: The active neurofeedback session will be done within the 7T MRI.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Neurofeedback
Description: The sham Neurofeedback resembles the active condition but participants will not see their own brain activity and will instead view a past participant's active feedback from their same population group.
Study: NCT05921201

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Relax, Reflect, and Empower mobile application
Description: Participants in the RRE group will select an Avatar from a pool of 20 Avatars as their companion over the 3 months. The Avatar wellness check-in in the RRE group includes a daily wellness check-in of 5-minute/day (4 days/week), and a weekly full wellness check-in of 15 minutes/week for 3 months. The daily brief check-in includes a wellbeing and mood check and a 3-minute relaxation meditation. The weekly full wellness check-in includes reflection activities in addition to the daily check-in activities.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Relax, Reflect, and Empower mobile application
Description: Participants in the RRE group will select an Avatar from a pool of 20 Avatars as their companion over the 3 months. The Avatar wellness check-in in the RRE group includes a daily wellness check-in of 5-minute/day (4 days/week), and a weekly full wellness check-in of 15 minutes/week for 3 months. The daily brief check-in includes a wellbeing and mood check and a 3-minute relaxation meditation. The weekly full wellness check-in includes reflection activities in addition to the daily check-in activities.
Study: NCT05334914

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Acceptance Commitment Therapy
Description: ACT: Consists of 15 sessions, twice per week. Each session is approximately 2.5 hours including breaks. Clients cover 3 modules (OPEN, ACTIVE, AWARE). Any participant who requires access to a device for any part of the study will be provided with one for the duration of the study.~CM: Participants will be given progressive compensation for session attendance via gift cards or e-gift cards amounting to $520.~Motivation Building Session: The study clinician will meet with each of the participants to explain the process of the therapy, reinforce expectations, and address any concerns or hesitations, and build motivation and commitment to fully engage in the program.~ChillTime App Participants rate their emotional state and choose a coping strategy (either physical, emotional, cognitive or spiritual). The app's algorithm learns the individual's strategy preferences over time, allowing for more personalized suggestions. Participants are also able to access coping strategies ad hoc.
Study: NCT06680622

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bemarituzumab, paclitaxel, ramucirumab
Description: Cohort 2 will receive bemarituzumab plus SOC treatment with paclitaxel and ramucirumab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bemarituzumab, irinotecan
Description: Cohort 1 will receive bemarituzumab plus SOC treatment with irinotecan

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bemarituzumab, trifluridine/tipiracil
Description: Cohort 3 will receive bemarituzumab plus SOC treatment with trifluridine/tipiracil
Study: NCT06680518

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: tourniquet
Description: peroperation tourniquet

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No tourniquet
Description: no tourniquet during surgery
Study: NCT05000723

Intervention type: OTHER
Intervention: Standard of care
Description: Standard of care consisting of~* clearance of infection~* treatment with antibiotics (antisuppressive, DAIR) or surgery (1 stage, 2 stage Girdlestone)~* Radiology: X-ray pelvis and hip, X-ray pelvis with kingmark, CT scan pelvis/hip
Study: NCT04365920

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Recovery Management Checkups (RMC)
Description: The RMC model was designed to improve treatment linkage, engagement, and long-term treatment retention. The conceptual framework was based on the public health theory of chronic disease management, which utilizes ongoing assessment and monitoring through regular face-to-face checkups and early (re)intervention to facilitate detection of relapse, reduce the time to treatment re-entry, and consequently, improve long-term outcomes. The original RMC model includes: 1) a fixed schedule of face-to-face quarterly checkups to assess need for SUD treatment, 2) personalized feedback based on an assessment and motivational interviewing to increase treatment motivation, 3) problem solving around barriers to treatment access and retention, and 4) assistance with scheduling and linkage to treatment. Individuals were deemed to be in need of treatment if they reported weekly, or more frequent, substance use since the last checkup, any past-month SUD symptoms, or self-perceived need for treatment.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: RMC-Adaptive
Description: Participants in the RMC-Adaptive group will receive face-to-face monthly checkups during the first 2 months post-release with additional face-to-face checkups dependent upon the participant's progress. Based on the data presented in the prior section, as long as participants need treatment, they will receive monthly checkups.~In addition, for every checkup that a participant does NOT need treatment, the number of months before the next checkup will be increased by 1 month (e.g., after 2 checkups without need, they will receive the next checkup 2 months later, after 3 it will be 3 months, after 4 it will be 4 months, and so on). Based on these decision rules, individuals who have NO treatment need over 24 months will still receive 5 checkups.
Study: NCT05928260

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medtronic Guardian Connect Sensor 3
Description: This is a real-time CGMS which transmits all the blood glucose readings into the application downloaded in a device continuously and also gives alarms and alerts to the person.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Abott Freestyle Libre Sensor
Description: This system is an is-CGMS in which the participant gets his blood glucose only when the device is scanned.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Self blood Glucose monitoring by a glucometer
Description: In this all patients will check their blood glucose using a needle prick and glucometer at pre-specified intervals.
Study: NCT06257628

Intervention type: DEVICE
Intervention: Index Event
Description: Patients with at least one Beckman High Sensitivity Troponin test at the Emergency Department visit