TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04211259

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Loratadine
Description: Given PO

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT04014244

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Corticosteroid vs. Dextrose
Description: US guided injection of corticosteroid in one hand and 5% glucose in the other will be performed in accordance with randomization. In a syringe both substances will be diluted using 0.9% NaCl to a total injection volume of 6 ml. In-plane ulnar approach will be used to visualize the median nerve at the level of the pisiform bone. A standard 23 gauge needle will be inserted in the carpal tunnel with the needle tip positioned between retinaculum and median nerve.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Corticosteroid or Dextrose vs. Surgery
Description: Injection will be performed unilaterally, after randomization of sides, by the same examiner as in the first part of the study. In all patients included in the second part of the study surgical release will be performed by the same plastic surgeon. The procedure will be performed under local anesthesia, following the same standard protocol. Both treatments will be performed maximally 2 months after diagnosis, with maximum period between them of 1 week.
Study: NCT04866381

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-6390
Description: SHR-6390

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-6390 + Camrelizumab (SHR-1210)
Description: SHR-6390 combined with Camrelizumab (SHR-1210)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab (SHR-1210) + SHR-1020
Description: Camrelizumab (SHR-1210) combined with SHR-1020
Study: NCT06007196

Intervention type: DEVICE
Intervention: non-invasive device (Task Force CORE(R) and Task Force CARDIO(R)
Description: Intraoperative cardiac output will be measured using the non-invasive device (Task Force CORE(R) and Task Force CARDIO(R) and will be compared with the invasive thermodilution method (PiCCO).
Study: NCT05247346

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SENSITIVE system
Description: probe-based integrated Raman spectroscopy and scattering measurements of Barrett's and colorectal tissue during GI endoscopy
Study: NCT05263648

Intervention type: OTHER
Group type: OTHER
Intervention: Virtual Reality Session
Description: VR-based education sessions will be used to influence patients' perceived emotional and social distress while undergoing radiation therapy (RT).~Emotional and social distress levels will be evaluated using questionnaires at baseline (prior to the first VR experience), at completion of RT, and at 30-60 days post RT.
Study: NCT06344468

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early Mobilization
Description: Essentially, early mobilization practices consist of two parts: in-bed and out-of-bed. In-bed mobilization; Active-passive joint range of motion (ROM) Exercises include raising the head in bed, turning in bed, in-bed exercises and sitting at the end of the bed. Out-of-bed mobilization includes the process of transferring from bed to chair, standing up, and returning to bed after standing up. In studies conducted on cardiac surgery, the early mobilization period is the first 12 hours.
Study: NCT06109558

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LMV-12(HE003)
Description: 1 cycle was 28 days. LMV-12(HE003), 30mg or 60mg, continuously for 21 days, and the drug was discontinued for 7 days. Osimertinib, 80mg, continuously for 28 days.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LMV-12(HE003)
Description: 1 cycle was 28 days. LMV-12(HE003), 30mg or 60mg, continuously for 21 days, and the drug was discontinued for 7 days. Osimertinib, 80mg, continuously for 28 days.
Study: NCT06458790

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AARC
Description: This intervention will adapt an already-existing evidence-based Centering Parenting program addressing topics that are specific to African American families. There will be 9 90 min sessions via zoom and in person. Group education topics include (parenting goals, infant feeding and sleep, self-care). Participants will complete surveys and interviews at various times to evaluate the program. The survey topics will include: parent stress, parent confidence and thoughts about the intervention. Surveys will be completed independently by participants online via redcap at a time that is convenient to them; if requested, the coordinator may complete the survey with the participant directly by phone /zoom. Interviews will be completed with a coordinator via zoom/phone.
Study: NCT06524167

Intervention type: RADIATION
Intervention: adjuvant radiotherapy
Description: The patients would receive external radiation therapy within 6 weeks after surgery, using intensity-modulated radiation therapy (IMRT) or volume modulated radiation therapy (VMAT) techniques. 6MV-X-ray irradiation. Conventional segmented irradiation is used, once a day, five times a week, with a segmented dose of 2Gy per dose.
Study: NCT04858867

Intervention type: RADIATION
Group type: OTHER
Intervention: rhTSH-stimulated I-124 dosimetry
Description: Preparation:~* Low iodine diet 7 days prior to I-124 ingestion until 24 hours post-ingestion~* Thyrogen injections 24 and 48h prior to I-124 ingestion~Procedures following Jentzen et al:~* Ingestion of capsule with 37±10% MBq I-124~* I-124 PET/CT at 24 and 96h post-ingestion~* Blood draws at 2, 24 and 96h post-ingestion~* Whole body counting at 2, 24 and 96h post-ingestion

Intervention type: RADIATION
Group type: OTHER
Intervention: rhTSH-stimulated I-124 dosimetry
Description: Preparation:~* Low iodine diet 7 days prior to I-124 ingestion until 24 hours post-ingestion~* Thyrogen injections 24 and 48h prior to I-124 ingestion~Procedures following Jentzen et al:~* Ingestion of capsule with 37±10% MBq I-124~* I-124 PET/CT at 24 and 96h post-ingestion~* Blood draws at 2, 24 and 96h post-ingestion~* Whole body counting at 2, 24 and 96h post-ingestion

Intervention type: RADIATION
Group type: OTHER
Intervention: Intra-therapeutic I-131 dosimetry
Description: Procedures following EANM guidelines:~* I-131 SPECT/CT at 2, 6, 24, 96 and 144h post-ingestion~* Blood draws at 2, 6, 24, 96 and 144h post-ingestion~* Whole body counting at 2, 6, 24, 96 and 144h post-ingestion
Study: NCT05372081

Intervention type: OTHER
Intervention: Digital platform
Description: Patients will be randomized (1:1) in the way they will receive or not any assistance from the digital platform.

Intervention type: OTHER
Intervention: Digital platform
Description: Patients will be randomized (1:1) in the way they will receive or not any assistance from the digital platform.
Study: NCT06412393

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Black tomato extract powder
Description: take 2 packets per day for 8 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo powder
Description: take 2 packets per day for 8 weeks
Study: NCT05664256

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Build capacity of canteen
Description: The investigators will conduct 1 day orientation training to the school nurse, principal and canteen managers of the facilities.~Different sessions on basic nutrition concept, healthy eating, healthy cooking practices including purchasing and serving will be conducted.~The investigators will develop training manuals: training curriculum, facilitators guide, and participants guide, aligning with policy contents.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Information, Education and Communication materials
Description: Posters showing healthy plate model will be displayed on the canteen walls. The fact sheet on healthy eating will be distributed to all the public facilities and make it available at the entrance/ gate of the canteen.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Monitoring visit
Description: A monitoring team from each municipality will be formed. The monitoring plan will be prepared with the team. At least one monitoring visit from the municipality government with onsite feedback will be done.
Study: NCT04915092

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CoSIE app
Description: The app is a mobile phone application compatible with both iOS and Android operating system. Parents are able to register their children and to keep track of their weight status and activities. The app include five themes: child development, physical activity, healthy food, critical situations, BMI.~Push notification on healthy behaviours, on important event taking place in the province of Reggio Emilia, on food advices based on seasonality and on party tips are constantly delivered by the app.
Study: NCT06311903

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low dose of Norepinephrine (NE)
Description: Patients were received resuscitative fluid \[administered at beginning with the arrival of the patient in the emergency department (mean blood pressure \>70 mmHg)\] followed by low dose of NE (0.05-0.2 μg/kg/min).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose of Norepinephrine (NE)
Description: Patients were received resuscitative fluid. If there were no response to treatment to resuscitative fluid, they received NE gradually till reach high dose (≥0.3 μg/kg/min).
Study: NCT05948423

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tisue Flossing Technique
Description: Experimental Group (Tissue Flossing + conventional therapy) Tissue Flossing involved active and passive movement with elbow wrapped with a floss band made from latex rubber (7m x 2 inch) Floss band was wrapped around the elbow (distal to proximal) using 25% overlapping pattern with an elongation stretch of 25%. During treatment the compression of floss band was measured with modified sphygmomanometer by placing cuff under floss band (which is applied on muscle) and note the pressure on manometer.~Control Group (Conventional Therapy) Conventional therapy was applied for 23 minutes for both groups which include hot pack for 10 minutes, PNF (hold-relax with agonist contraction): It started with a gentle stretch of bicep muscle for 10 seconds followed by isometric contraction for 6 seconds then the patient tried to flex their elbow and the therapist also assisted.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tisue Flossing Technique
Description: Experimental Group (Tissue Flossing + conventional therapy) Tissue Flossing involved active and passive movement with elbow wrapped with a floss band made from latex rubber (7m x 2 inch) Floss band was wrapped around the elbow (distal to proximal) using 25% overlapping pattern with an elongation stretch of 25%. During treatment the compression of floss band was measured with modified sphygmomanometer by placing cuff under floss band (which is applied on muscle) and note the pressure on manometer.~Control Group (Conventional Therapy) Conventional therapy was applied for 23 minutes for both groups which include hot pack for 10 minutes, PNF (hold-relax with agonist contraction): It started with a gentle stretch of bicep muscle for 10 seconds followed by isometric contraction for 6 seconds then the patient tried to flex their elbow and the therapist also assisted.
Study: NCT05508815

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modified Zhiwang Decoction Combined with methotrexate
Description: Modified Zhiwang Decoction 100 ml (twice, per day) and methotrexate (7.5-15mg, once a week) for 12 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methotrexate
Description: Methotrexate(7.5-15mg, once a week) for 12 weeks.
Study: NCT05233475

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced usual care (EUC)
Description: Enhanced usual care (EUC):~All participants will by a health professional be shortly informed about the typical recovery process, the given reassurance about the prognosis.as well as advice on adaptive illness behaviours post-concussion.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced usual care (EUC)
Description: Enhanced usual care (EUC):~All participants will by a health professional be shortly informed about the typical recovery process, the given reassurance about the prognosis.as well as advice on adaptive illness behaviours post-concussion.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Get Going after concussIoN Lite
Description: GAIN Lite:~GAIN Lite in an add-on to EUC, and contains two major components: 1) self-administrated e-learning videos and 2) up to four hours video- or phone sessions with an allocated therapist (either an occupational- or a physiotherapist) during a period of 8 weeks. Health professionals provide feedback and guidance, addressing the specific aims and context of the individual.
Study: NCT06179745

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: EEG-based brain-computer interface
Description: EEG-based brain-computer interface detecting the patient's EEG sensorimotor rhythms associated to attempted reach-gasp-release upper limb movements by the patient.

Intervention type: COMBINATION_PRODUCT
Group type: SHAM_COMPARATOR
Intervention: Sham EEG-based brain-computer interface
Description: Fake (Sham) EEG-based brain-computer interface which outputs a decision at random about whether EEG sensorimotor rhythms associated to attempted reach-gasp-release upper limb movements by the patient are currently detected.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Functional Electrical Stimulation
Description: Neuromuscular stimulation of several upper limb muscles (elbow extensors, hand extensors/flexors) to effectuate reach, grasp and release movements of the affected upper limb.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Functional Electrical Stimulation
Description: Neuromuscular stimulation of several upper limb muscles (elbow extensors, hand extensors/flexors) to effectuate reach, grasp and release movements of the affected upper limb.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active hand orthosis
Description: Active hand orthosis effectuating reach, grasp and release movements of the affected uppe r limb.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Active hand orthosis
Description: Active hand orthosis effectuating reach, grasp and release movements of the affected uppe r limb.
Study: NCT05017051

Intervention type: BEHAVIORAL
Intervention: Chocolate cake
Description: The participants will have to make a chocolate cake following an imposed recipe at 4 visits (initially (M0), after 12 months (M12), after 24 months (M24) and after 36 months (M36)).

Intervention type: BEHAVIORAL
Intervention: Chocolate cake
Description: The participants will have to make a chocolate cake following an imposed recipe at 4 visits (initially (M0), after 12 months (M12), after 24 months (M24) and after 36 months (M36)).

Intervention type: BEHAVIORAL
Intervention: Lego model
Description: The participants will have to build a Lego model at 4 visits (M0, M12, M24 and M36).

Intervention type: BEHAVIORAL
Intervention: Lego model
Description: The participants will have to build a Lego model at 4 visits (M0, M12, M24 and M36).

Intervention type: DEVICE
Intervention: Measurement of sensorimotor abilities
Description: The measurement of sensorimotor abilities is based on a multi-sensor device called Smart Flat specifically designed for this study at 4 visits (M0, M12, M24 and M36).

Intervention type: DEVICE
Intervention: Measurement of sensorimotor abilities
Description: The measurement of sensorimotor abilities is based on a multi-sensor device called Smart Flat specifically designed for this study at 4 visits (M0, M12, M24 and M36).

Intervention type: OTHER
Intervention: Measurement of facial expression of emotions
Description: Participants will have to evoke an emotionally charged autobiographical story by modulating facial expressions through a mirror at 4 visits (M0, M12, M24 and M36).

Intervention type: OTHER
Intervention: Measurement of facial expression of emotions
Description: Participants will have to evoke an emotionally charged autobiographical story by modulating facial expressions through a mirror at 4 visits (M0, M12, M24 and M36).
Study: NCT05627453

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Arm-in-arm gait training
Description: An older adult walk side-by-side, arm-in-arm with a younger adult while synchronizing steps.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Normal gait training
Description: An older adult walk side-by-side, without contact, with a younger adult without step synchronization.
Study: NCT04858867

Intervention type: RADIATION
Group type: OTHER
Intervention: Intra-therapeutic I-131 dosimetry
Description: Procedures following EANM guidelines:~* I-131 SPECT/CT at 2, 6, 24, 96 and 144h post-ingestion~* Blood draws at 2, 6, 24, 96 and 144h post-ingestion~* Whole body counting at 2, 6, 24, 96 and 144h post-ingestion
Study: NCT05056155

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Systane Complete
Description: Propylene glycol 0.6% eye drops for replenishing deficiencies in both the lipid and aqueous layers of the tear film
Study: NCT04932135

Intervention type: DIAGNOSTIC_TEST
Intervention: Continuous heart rate monitoring
Description: Continuous heart rate monitoring with a wrist worn fitnesstracker

Intervention type: DIAGNOSTIC_TEST
Intervention: Continuous heart rate monitoring
Description: Continuous heart rate monitoring with a wrist worn fitnesstracker
Study: NCT05343299

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Ambulatory surgery under Lidocaine alone
Description: In this conventional procedure group, the anesthetic solution is administered subcutaneously and by infiltration into the surgical area. A maximum volume of 20 ml (dose dictated by the operation) of the solution is thus injected by the operator: Lidocaine 10mg/mL combined with adrenaline 0.005mg/mL administered at a dose of 10 to 20 mL, i.e. a total of 50 to 200 mg of lidocaine.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Ambulatory surgery under a combination of Lidocaine and Ropivacaine
Description: In this experimental procedure group, the anesthetic solution is administered subcutaneously and by infiltration into the surgical area. A maximum volume of 20 ml (dose dictated by the operation) of the solution is thus injected by the operator: Lidocaine 10mg/mL combined with adrenaline 0.005mg/mL administered at a dose of 18 mL + ropivacaine 7.5 mg/mL 2 mL or 15 mg. For a total of 20 mL: lidocaine 9mg/mL, ropivacaine 0.75 mg/mL, adrenaline 0.005 mg/mL
Study: NCT04750941

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Copanlisib
Description: Copanlisib will be infused intravenously on days 1, 8, 15 of each cycle, over 1 hour, of 28-day cycles.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Copanlisib
Description: Copanlisib will be infused intravenously on days 1, 8, 15 of each cycle, over 1 hour, of 28-day cycles.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic Diet
Description: In cycle 1, patients will first start the ketogenic diet for 7 days (Day -6 to Day 0).~Only the patients who demonstrate compliance and tolerance with the ketogenic diet, as confirmed by pertinent blood and urine tests and a diary of diet, will be allowed to continue the study and start copanlisib on Day 1. The ketogenic diet will continue daily throughout the treatment days.~In cycle 2 and beyond, patients will start the ketogenic diet and copanlisib on day 1.~The ketogenic diet will then continue daily throughout the treatment days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic Diet
Description: In cycle 1, patients will first start the ketogenic diet for 7 days (Day -6 to Day 0).~Only the patients who demonstrate compliance and tolerance with the ketogenic diet, as confirmed by pertinent blood and urine tests and a diary of diet, will be allowed to continue the study and start copanlisib on Day 1. The ketogenic diet will continue daily throughout the treatment days.~In cycle 2 and beyond, patients will start the ketogenic diet and copanlisib on day 1.~The ketogenic diet will then continue daily throughout the treatment days.
Study: NCT05656794

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Standard of care radiotherapy administered as per institutional guidelines.

Intervention type: RADIATION
Group type: OTHER
Intervention: Radiotherapy
Description: Standard of care radiotherapy administered as per institutional guidelines.
Study: NCT05109000

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Chloride 0.9% Inj
Description: 10 mL subcutaneous injection into one randomized anterior thigh of subject

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
Description: 10 mL subcutaneous injection into the contralateral anterior thigh of subject
Study: NCT04855305

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyperpolarized 129Xe
Description: Hyperpolarized 129Xe will be administered in multiple doses in volumes that are tailored to the participant's total lung capacity (TLC) followed by a breath hold of up to 15 seconds.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyperpolarized 129Xe
Description: Hyperpolarized 129Xe will be administered in multiple doses in volumes that are tailored to the participant's total lung capacity (TLC) followed by a breath hold of up to 15 seconds.
Study: NCT05754541

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WeFlow-Tribranch Aortic Arch Stent Graft System
Description: Endovascular treament in patients with aortic arch dissection and aneurysm by WeFlow-Tribranch Aortic Arch Stent Graft System
Study: NCT05618158

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 4 Corners Rural Health Cancer Prevention
Description: Participants, aged 18-26, will join a private Facebook group to participate in the intervention. The group is not viewable to the public, including other Facebook users. Content that focuses on cancer prevention behaviors will be posted twice per day for up to 12 months. Each group will be hosted by a moderator who is responsible for managing the intervention goals and participants' engagement.
Study: NCT06149104

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sacubitril/valsartan
Description: sacubiril/valsartan