TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06101667

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Best medical management
Description: Best medical management included assessment of vital signs and neurological deficits,airway protection respiratory support,circulation;blood pressure monitoring;nutritional support;complication control;symptomatic treatment;laboratory and imaging examinations;etiological analysis and evaluation; anti platelet（e.g. aspirin,adenosine diphosphate (ADP) receptor inhibitors,Adenosine reuptake inhibitors,Glycoprotein platelet inhibitors）；anticoagulation(e.g. warfarin, rivaroxaban,dabigatran,apixaban,edoxaban)；lipid lowering(e.g. Statins,Fibrates）；control of blood pressure(e.g. Thiazide diuretics,Potassium-sparing,Loop diuretic,Beta-blockers,Angiotensin II receptor blockers,Calcium channel blockers,Alpha blockers,Central alpha-2 receptor agonists);control of blood glucose(e.g. SULFONYLUREAS (SFUs),GLINIDES,BIGUANIDES,ALPHA-GLUCOSIDASE INHIBITORS: STARCH BLOCKERS,THIAZOLIDINEDIONES,GLP-1 ANALOGS,DPP-4 INHIBITORS,SGLT2 inhibitors); control of other risk factors

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endovascular treatment
Description: The strategies that were used for endovascular treatment included :stent retrievers (e.g., Solitaire® \[Medtronic, USA\], Trevo® \[Stryker, USA\], EMBOTRAP® \[Johnson \& Johnson, USA\], Captor® \[HeartCare, China\] and other stent-retriever systems) thromboaspiration (e.g., Penumbra® \[Penumbra, USA\], Afentta® \[HeMo, China\] and other aspiration systems)) balloon angioplasty (e.g., Gateway® \[Stryker, USA\], Neuro RX® \[SinoMed, China\], FocuStar® \[HeMo, China\] and other intracranial balloon catheter systems) stent deployment (e.g., Wingspan® \[Stryker, USA\], Apollo® \[MircoPort, China\], Enterprise® \[Johnson \& Johnson, USA\], Neuroform EZ® \[Stryker, USA\] and other Intracranial stent systems)) intraarterial thrombolysis (with alteplase or urokinase) combinations of above approaches that were left to the discretion of the treating team
Study: NCT04275791

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Triage
Description: Experimental : Trauma patient orientation in a structured regional health organization, composed of trauma centers hierarchized in several levels according to their capacity to receive severe traumatized persons.
Study: NCT05634460

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: potassium hydroxide
Description: Potassium hydroxide (KOH) is a topical treatment for Molluscum contagiosum. Dermatologists routinely use potassium hydroxide (KOH) in varying concentrations to identify fungal elements. Because it is a strong alkali with keratolytic characteristics, variable concentrations given for management of MC.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: potassium hydroxide
Description: Potassium hydroxide (KOH) is a topical treatment for Molluscum contagiosum. Dermatologists routinely use potassium hydroxide (KOH) in varying concentrations to identify fungal elements. Because it is a strong alkali with keratolytic characteristics, variable concentrations given for management of MC.
Study: NCT05098860

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home Exercise Program
Description: Educational training program includes active stretching, strengthening, and stabilization exercises of head and neck muscles as well as relaxation and breathing exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual Therapy Combined with Home Exercise Program
Description: Manual Therapy program includes soft tissue and joint mobilizations of the cervical vertebrae, scapula and thoracic vertebrae.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tele-rehabilitation Assisted Program
Description: Tele-rehabilitation assisted program will be given in the on-line environment. Patients will apply active cervical and thoracic region mobilizations called self-mobilization.
Study: NCT06096220

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Enucleation
Description: Enucleation is complete removal of the cyst from the bony defect of the jaw affected by the lesion. Osteotomy is performed to allow access to the cyst, cystic wall is detached from the bone and removed completely.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Enucleation
Description: Enucleation is complete removal of the cyst from the bony defect of the jaw affected by the lesion. Osteotomy is performed to allow access to the cyst, cystic wall is detached from the bone and removed completely.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: incisional biopsy
Description: Lesions clinically abd radiographically consistent with OKC will be submitted for histological examination to confirm the diagnosis of OKC

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: incisional biopsy
Description: Lesions clinically abd radiographically consistent with OKC will be submitted for histological examination to confirm the diagnosis of OKC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Application of 5-fluorouracil
Description: 5% 5-fluorouracil cream will be applied immediately after the enucleation to the cystic cavity for 24 hours

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Application of Carnoy solution
Description: Carnoy solution will be applied during the enucleation as described previously
Study: NCT04790760

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Supplement Consumption
Description: Participants will consume one 500 mg cinnamon capsule and one 300 mg aloe vera capsule twice per day for weeks 3-6.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous Glucose Monitors
Description: Participants will wear a CGM on the back of their left and right arm for weeks 1-6.
Study: NCT05303207

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: YOUR SUPER Detox Bundle
Description: During days 1-5, participants will complete the 5-day Your Super Detox, consuming 2 smoothies daily (breakfast and dinner) containing Your Super Detox superfood powders.
Study: NCT04534907

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: The combination of exposure and response prevention (ERP) and VR
Description: The combination of exposure and response prevention (ERP) and VR aimed to investigate the combination of an immersive virtual reality environment (VRE) alongside therapist delivered CBT to reduce anxiety when the OCD patients were induced by virtual scene.Specially, patients will get the first CBT session in the first week for 90 minutes in order to gather detailed information of individual's symptom. Then the next 2 weeks, patients will get VR+ERP session twice a week. From the fourth week to the seventh week, patients weill get VR+ERP session once a week. In the end of the eighth week, patients will get the last session of the exposure-based CBT for relapse prevention.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional ERP
Description: Patients will achieve the exposure based CBT for total 10 times excluding 8 sessions of ERP. Structured protocol described by Foa et al., 2012. Specially, patients will get the first CBT session in the first week for 90 minutes in order to gather detailed information of individual's symptom. Then the next 2 weeks, patients will get ERP session twice a week. From the fourth week to the seventh week, patients weill get ERP session once a week. In the end of the eighth week, patients will get the last session of the exposure-based CBT for relapse prevention.
Study: NCT04731363

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: xylitol, 30g
Description: Intervention is a drink consisting of 300mL of water containing 30g of xylitol as a single oral dose.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: erythritol, 30g
Description: Intervention is a drink consisting of 300mL of water containing 30g of erythritol as a single oral dose.

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: xylitol, 5g
Description: Intervention is a drink consisting of 300mL of water containing 5g of xylitol as a single oral dose.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: glucose, 30g
Description: Intervention is a drink consisting of 300mL of water containing 30g of glucose (dextrose) as a single oral dose.
Study: NCT06394752

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Visual Saline Infusion
Description: Visual Saline Infusion (VSI) is a new intrauterine imaging procedure to identify uterine pathology. The VSI device is a 2.7mm, steerable tip catheter with a camera and illumination at the distal end. The device is intended to evaluate the intrauterine space in an office based, outpatient setting using minimal volume of fluid (3-5cc's).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hydrosonography
Description: Hydrosonography is an ultrasound based intrauterine imaging technique with sensitivity and specificity ranging from 90% to 100% for identifying uterine pathology. It is performed by inserting a slim 2 mm catheter into the uterine cavity and infusing saline solution to expand the uterus and using abdominal ultrasound to visualize the uterus.
Study: NCT06608394

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention

Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study: NCT05374577

Intervention type: OTHER
Intervention: pulmonary vascular dysfunction
Description: Right ventricular function determined by echocardiography at rest and during exercise (non-invasive estimation of ventilation-perfusion mismatch), systemic endothelial function, left heart function, and plasma levels of vasoactive biomarkers compared with clinical parameters of dyspnea and exercise capacity. Further examinations will be performed in patients with still unclear cause of persistent shortness of breath after 3 months of follow-up (subgroup RHC)

Intervention type: OTHER
Intervention: pulmonary vascular function
Description: Right ventricular function determined by echocardiography at rest and during exercise (non-invasive estimation of ventilation-perfusion mismatch), systemic endothelial function, and plasma levels of vasoactive biomarkers compared with clinical parameters of dyspnea and exercise capacity.
Study: NCT06396715

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial direct current stimulation
Description: tDCS is a type of non-invasive brain stimulation that in a standard paradigm, low intensity current (1-2 mA) is applied continuously through a battery connected to two 20 to 35 cm2 surface electrodes located on the scalp: an anode and a cathode. In the interhemispheric competition model, tDCS can serve as a means to increase ipsilesional cortical excitability through anodal stimulation, to decrease contralesional cortical excitability through cathodal stimulation, or to do both through a montage of bi-hemispheric electrodes.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation
Description: tDCS is a type of non-invasive brain stimulation that in a standard paradigm, low intensity current (1-2 mA) is applied continuously through a battery connected to two 20 to 35 cm2 surface electrodes located on the scalp: an anode and a cathode. In the interhemispheric competition model, tDCS can serve as a means to increase ipsilesional cortical excitability through anodal stimulation, to decrease contralesional cortical excitability through cathodal stimulation, or to do both through a montage of bi-hemispheric electrodes.
Study: NCT06290713

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil
Description: Patients will be given either the intervention medication or a placebo (double-blinded, randomized trial) and will be asked to take the medication every day for 6 months in conjunction with weekly exercise sessions.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will be given either the intervention medication or a placebo (double-blinded, randomized trial) and will be asked to take the medication every day for 6 months in conjunction with weekly exercise sessions.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Exercise Training
Description: The home-based cycling exercise training program is designed to improve muscle strength and endurance. Participants will engage in individualized exercise sessions up to four times per week, lasting up to 40 minutes each. Live video and heart rate monitoring will ensure proper exercise performance and allow for adjustments to the program throughout the study. The participants will receive the exercise equipment for use at home.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Training
Description: The home-based cycling exercise training program is designed to improve muscle strength and endurance. Participants will engage in individualized exercise sessions up to four times per week, lasting up to 40 minutes each. Live video and heart rate monitoring will ensure proper exercise performance and allow for adjustments to the program throughout the study. The participants will receive the exercise equipment for use at home.
Study: NCT06178016

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bystander Intervention Program for Dating Violence
Description: The Bystander Intervention Program for Dating Violence includes the following topics: Dating violence and its types (Session 1), risk factors and consequences of dating violence (Session 2), bystander intervention in dating violence and barriers to intervention (Session 3), bystander intervention strategies for dating violence (Session 4), self-care for bystanders witnessing dating violence (Session 5).~Each session is planned to last 60-90 minutes. Materials will be used in the Bystander Intervention Program for Dating Violence are PPT (PowerPoint Presentations) slides, videos, interactive scenarios, and group discussions. The Bystander Intervention Program for Dating Violence is planned to be applied face-to-face in 4 groups (12, 10, and 10 people) at scheduled times in a quiet room suitable for the group.
Study: NCT06013956

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neurostimulation
Description: Electrical stimulation delivered via deep brain stimulation electrodes based on measurements of brain activity.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neurostimulation
Description: Electrical stimulation delivered via deep brain stimulation electrodes based on measurements of brain activity.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbidopa 25/Levodopa 100Mg Tab
Description: Anti-parkinsonian medication.
Study: NCT04104919

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivoligide Injection 660 mg/6 mL
Description: Single preoperative intrathecal injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 6 mL
Description: Single preoperative intrathecal injection
Study: NCT05630651

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: ZS801
Description: A novel, bioengineered adeno-associated viral (AAV) vector carrying human factor IX variant. The dose level is 5.0×10\^12vg/kg.
Study: NCT04698135

Intervention type: OTHER
Intervention: Biological samples collection
Description: Collection of faeces, coproculture examination, urine, saliva, PBMC and blood for biobanking, to evaluate the proteomic, metascriptomic, metabolomic, metagenomic, and metagenetic profile, and to perform routine screening. Analysis for the identification, quantification and characterization of health-promoting bacteria

Intervention type: OTHER
Intervention: Biological samples collection
Description: Collection of faeces, coproculture examination, urine, saliva, PBMC and blood for biobanking, to evaluate the proteomic, metascriptomic, metabolomic, metagenomic, and metagenetic profile, and to perform routine screening. Analysis for the identification, quantification and characterization of health-promoting bacteria

Intervention type: OTHER
Intervention: Biological samples collection
Description: Collection of faeces, coproculture examination, urine, saliva, PBMC and blood for biobanking, to evaluate the proteomic, metascriptomic, metabolomic, metagenomic, and metagenetic profile, and to perform routine screening. Analysis for the identification, quantification and characterization of health-promoting bacteria

Intervention type: OTHER
Intervention: Questionnaire
Description: Anamnestic questionnaire, 3-day food questionnaire, Food Frequency Questionnaire

Intervention type: OTHER
Intervention: Questionnaire
Description: Anamnestic questionnaire, 3-day food questionnaire, Food Frequency Questionnaire

Intervention type: OTHER
Intervention: Questionnaire
Description: Anamnestic questionnaire, 3-day food questionnaire, Food Frequency Questionnaire

Intervention type: OTHER
Intervention: Medical/laboratory examinations
Description: Blood pressure measurement, abdominal and thoracic physical examination, body composition through bioimpedance analysis and metabolic, cardiovascular and respiratory variables; OGTT 75gr for blood glucose and insulin at times 0, 30, 60, 90 and 120', and a nocturnal oximetry and subsequently, if necessary, overnight polysomnography for the diagnosis of obstructive sleep

Intervention type: OTHER
Intervention: Medical/laboratory examinations
Description: Blood pressure measurement, abdominal and thoracic physical examination, body composition through bioimpedance analysis and metabolic, cardiovascular and respiratory variables; OGTT 75gr for blood glucose and insulin at times 0, 30, 60, 90 and 120', and a nocturnal oximetry and subsequently, if necessary, overnight polysomnography for the diagnosis of obstructive sleep

Intervention type: OTHER
Intervention: Medical/laboratory examinations
Description: Blood pressure measurement, abdominal and thoracic physical examination, body composition through bioimpedance analysis and metabolic, cardiovascular and respiratory variables; OGTT 75gr for blood glucose and insulin at times 0, 30, 60, 90 and 120', and a nocturnal oximetry and subsequently, if necessary, overnight polysomnography for the diagnosis of obstructive sleep
Study: NCT05961176

Intervention type: DEVICE
Intervention: Skiin pediatric band and Skiin biometric pod
Description: Infants that meet the inclusion criteria will be equipped with a Skiin pediatric band appropriate for their chest size. Heart rate, respiratory rate, temperature, and electrocardiogram will be monitored from 2 to 12 hours through the Skiin pediatric band and a standard of care device (Phillips Intellivue MX750) commonly used in the CCCU at SickKids.
Study: NCT05748184

Intervention type: DEVICE
Intervention: PACS viewer prototype
Description: A PACS system mimicking the clinical PACS system used in LUMC.

Intervention type: DEVICE
Intervention: Optimized ULDCT viewer prototype version(s)
Description: The ULDCT viewer prototype is a non-medical unreleased device that will be used by study participants on de-identified image cases in a research setting. The Prototype integrates new tools to speed up the diagnostic interpretation process of radiological images. Optimized version(s) of previous version.
Study: NCT06430931

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Minimal invasive abdominal prolapse surgery using Polypropylene mesh
Description: All procedures will be performed with robotic assistance of the da Vinci Si-HD (intuitive Surgical, Inc, Sunnyvale, CA).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Minimal invasive abdominal prolapse surgery using OviTex 1S permanent mesh
Description: All procedures will be performed with robotic assistance of the da Vinci Si-HD (intuitive Surgical, Inc, Sunnyvale, CA).
Study: NCT04421235

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Childbirth support
Description: There are 5 program components that women may receive as a part of childbirth support:~Prenatal education - consists of up to 8 sessions of education on pregnancy, childbirth, and postpartum health and wellness.~Support group - semi-structured group which provides time for women to process their pregnancy and postpartum-related experiences with other women facing similar challenges. Integrates mindfulness exercises, cognitive-behavioral skills, and special topics as requested by group members.~Lactation program - program for women who wish to provide breastmilk for infants from which they are separated.~Doula support program - 2 prenatal and 2 postnatal individual visits with a doula who will also provide continuous childbirth support and support during separation from infants.~Parenting classes - group classes focused on helping women learn parenting skills and (if applicable) meet state requirements for reunification with children
Study: NCT06448260

Intervention type: OTHER
Intervention: Questionnary
Description: Data from theses patients will be collected in our personnal data base with ask of consent according to the law Then each patient alive will have questionnary to answer by phone or during a visit.
Study: NCT05443178

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivaquine ® (Chloroquine)
Description: dose escalation and extension trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivaquine ® (Chloroquine)
Description: dose escalation and extension trial

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivaquine ® (Chloroquine)
Description: dose escalation and extension trial
Study: NCT04154085

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychotherapy
Description: Group psychotherapy
Study: NCT05913791

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutrients-fortified egg
Description: Consumption of 2 cooked nutrients fortified eggs (half-boiled, hard-boiled, or steamed)

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Regular egg
Description: Consumption of 2 regular eggs, prepared in the same manner as nutrients-fortified egg, which serves as a placebo comparison.
Study: NCT05870163

Intervention type: DEVICE
Intervention: RefluxStop implantation
Description: Standard surgical technique for implantation RefluxStop, as described in the Itructions for Use

Intervention type: PROCEDURE
Intervention: Nissen fundoplication
Description: Standard of care Nissen fundoplication surgery
Study: NCT05443178

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivaquine ® (Chloroquine)
Description: dose escalation and extension trial
Study: NCT05939583

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Shock Wave Therapy
Description: Receiving Shock wave therapy + US, TENS, IR and exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: US, TENS, IR and exercises.
Description: Receiving US, TENS, IR and exercises only.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: US, TENS, IR and exercises.
Description: Receiving US, TENS, IR and exercises only.