TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06342154

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Endorphin Massage
Description: The person who will perform the endorphin massage opens his hands with his palms facing himself and draws a semicircle with the nails of his middle, ring and little fingers touching the sacrum. Then, a semicircle is drawn with the fingertips from each side of the spine, starting from the sacrum to the shoulder area, towards the waist area, As a result of this process, a palm shape is drawn on the back. Effleurage is applied from the shoulders to the arms up to the elbows. Effleurage is applied towards the shoulders by pressing from the elbows upwards with the back of the thumb. Effleurage is applied up to the sacrum by pressing circular movements with two thumbs on both sides of the spine. Effleurage is applied from the sacrum to the neck by pressing with two thumbs in a circular motion on both sides of the spine (approximately 1.5 cm apart). Lastly, effleurage is applied to the neck area and scalp, then petrissage (rubbing) is applied and the massage is completed.
Study: NCT06718933

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-A1811
Description: ADC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-A1811
Description: ADC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: bevacizumab biosimilar

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib
Description: anti-HER2 inhibitor

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib
Description: anti-HER2 inhibitor
Study: NCT05444322

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RD14-01 cell infusion
Description: Autologous CAR T cells
Study: NCT04667702

Intervention type: BEHAVIORAL
Intervention: Interviews
Description: We will conduct a phone or virtual interview with patients with sickle cell disease or cancer, caregivers and their healthcare providers.

Intervention type: BEHAVIORAL
Intervention: Interviews
Description: We will conduct a phone or virtual interview with patients with sickle cell disease or cancer, caregivers and their healthcare providers.

Intervention type: BEHAVIORAL
Intervention: Interviews
Description: We will conduct a phone or virtual interview with patients with sickle cell disease or cancer, caregivers and their healthcare providers.
Study: NCT06186102

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Spermidine
Description: Spermidine capsule of 8 mg x 3 capsules daily.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsule. 3 capsules daily.
Study: NCT06489938

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mirror therapy
Description: In mirror therapy, a wooden mirror (41×50×33 cm3) will be positioned in the participant's sagittal midplane, blocking the participant's view of the affected arm performance. We will also provide a foldable bed tray table to ensure that the participants focus on the mirror reflection of the less affected arm. The mirror therapy will consist of movement and functional practices.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mirror therapy
Description: In mirror therapy, a wooden mirror (41×50×33 cm3) will be positioned in the participant's sagittal midplane, blocking the participant's view of the affected arm performance. We will also provide a foldable bed tray table to ensure that the participants focus on the mirror reflection of the less affected arm. The mirror therapy will consist of movement and functional practices.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Task-oriented approach
Description: The task-oriented approach will provide both bimanual common-goal and dual-goal tasks for the participants.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Task-oriented approach
Description: The task-oriented approach will provide both bimanual common-goal and dual-goal tasks for the participants.
Study: NCT06716788

Intervention type: DRUG
Intervention: 68Ga-HSA
Description: 68Ga-HSA PET/CT: after intravenous injection of 2.22 MBq/kg body weight of quality-controlled 68Ga-HSA, a Siemens Biograph PET/CT scan will be applied within 1 h, and the scan range will be from the top of the head to 1/3 of the upper thigh.
Study: NCT06718608

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: imaging
Description: Magnetic resonance imaging (MRI) Shear wave elastography (SWE) Electronic oscillatory device (EOD)
Study: NCT06714877

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: prism treatment group
Description: wearing prism glasses
Study: NCT06105125

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rigenera + bone substitute
Description: Minimally invasive flap elevation and debridement of the intrabony defect with micro-curettes. A small punch of connective tissue will be harvested from the palate in the premolar region. Then the graft will be mechanically dissociated using the Rigenera Machine System rotating speed to 80 rpm, in 1.0 ml sterile physiologic solution. After dissociation, the cellular suspension will be passed through a disposable grid with 100 hexagonal blades filtering cells and components of extracellular matrix with a cut-off of 50 um in an average time of 90 s. Finally, part of the suspension containing AMGs will be seeded on the scaffold material and subsequently compacted within the defect. Flaps will be positioned at the pre-surgical level or slightly coronal without any tension.
Study: NCT05184309

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Serious games
Description: A Serious game program will be applied to the individuals twice a week for 6 weeks in this group. Armrotate, Uball, Balance Surf and Balance Adventure games will be developed by Becure company for shoulder rehabilitation. These games developed for shoulder rehabilitation will be applied to individuals under the supervision of a physiotherapist. Each game will be played for 10 minutes, for a total of 40 minutes.
Study: NCT05590767

Intervention type: PROCEDURE
Intervention: Patients scheduled to undergo shoulder rotators repair surgery
Description: Patients scheduled to undergo shoulder rotators repair surgery, and received combined general anesthesia and interscalene block
Study: NCT06295432

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DZD9008+AZD4205
Description: Daily dose of DZD9008+AZD4205 until intolerant, disease progression or patient decision. Starting dose of DZD9008 is 200mg once daily and starting dose of AZD4205 is 75mg once daily orally used. If tolerated, subsequent cohorts will evaluate increasing doses of the combination therapy.
Study: NCT05866653

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: lidocaine transdermal patch
Description: The topical pain-relieving treatment 5% lidocaine transdermal patch has been registered in the USA since 1999

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: lidocaine transdermal patch
Description: The topical pain-relieving treatment 5% lidocaine transdermal patch has been registered in the USA since 1999
Study: NCT05217953

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LovedBy App
Description: The LovedBy solution aims to leverage modern technologies such as smartphones, continuous glucose monitors (CGM), and other smart wearables to assist young sufferers managing their condition. The LovedBy platform offers a mobile application which connects to the user's smart wearables and CGM to monitor data streams that have been linked to long term risk. The mobile application is then able to deliver personally relevant educational content to the user through numerous channels including private social media message
Study: NCT06003257

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: stainless steel crown
Description: stainless steel full coverage crown for deciduous teeth

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: zirconia crown
Description: zirconia full coverage crown for deciduous teeth

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: fiberglass crown
Description: fiberglass full coverage crown for deciduous teeth
Study: NCT05040789

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CoVLP formulation
Description: The Coronavirus-Like Particle (CoVLP) COVID-19 Vaccine is composed of recombinant spike (S) glycoprotein expressed as virus-like particles (VLPs).~The 3.75 µg dose of CoVLP will be administered with the adjuvant AS03 (manufactured by GlaxoSmithKline).

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CoVLP formulation
Description: The Coronavirus-Like Particle (CoVLP) COVID-19 Vaccine is composed of recombinant spike (S) glycoprotein expressed as virus-like particles (VLPs).~The 3.75 µg dose of CoVLP will be administered with the adjuvant AS03 (manufactured by GlaxoSmithKline).
Study: NCT06105125

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bone substitute alone
Description: Minimally invasive flap elevation and debridement of the intrabony defect with micro-curettes. The defect will be filled with the same bone substitute employed in the test group. Finally, flaps will be positioned at the pre-surgical level or slightly coronal without any tension.
Study: NCT05096806

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture is a non-pharmacological technique that consists in the stimulation of specific points located in the skin surface. Points are stimulated by piercing the skin with fine needles.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TENS
Description: TENS is a therapy that uses low voltage electrical current to provide pain relief. A TENS unit consists of a battery-powered device that delivers electrical impulses through electrodes placed on the surface of your skin. The electrodes are placed at or near nerves where the pain is located or at trigger points.
Study: NCT06006052

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: regeneration technique
Description: clinical procedure of regenerative endodontic as AAE mentioned using different material in each group

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: regeneration technique
Description: clinical procedure of regenerative endodontic as AAE mentioned using different material in each group

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: regeneration technique
Description: clinical procedure of regenerative endodontic as AAE mentioned using different material in each group
Study: NCT04802148

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: membrane guided regeneration
Description: after tooth extraction, the socket was filled with membrane and graft (FDBA)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: collagen plug
Description: after tooth extraction, the socket was filled with collagen plug
Study: NCT06473090

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video group
Description: Participants will watch a 15-minute educational video at the beginning of the session before their involvement in the 2 high-fidelity simulation scenarios.~The educational video used was developed by experts (in Human Factors and Obstetric Anesthesia) and validated by SFAR and CARO. It depicts poor use of NTS (including CLC) during a maternal cardiac arrest anesthesia scenario and then proper use of NTS during the same scenario.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Text group
Description: Participants will read a text-type educational support for 15 minutes at the beginning of the session before their involvement in 2 high-fidelity crisis simulation scenarios.~The text-type educational support, written in French by the same team of experts, covers all the NTS mentioned in the video and has already been used in a previous study
Study: NCT04526834

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD30.CAR-T
Description: Bendamustine and Fludarabine (3 days)~Dose level 1: 2 x 108 cell/m2 CD30.CAR-T (Day 0)~Dose level 2: 4 x 108 cell/m2 CD30.CAR-T (Day 0)~Dose level 3: 6 x 108 cell/m2 CD30.CAR-T (Day 0)
Study: NCT06714877

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: botulinum toxin group
Description: botulinum toxin injection
Study: NCT06717048

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.
Study: NCT05040789

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CoVLP formulation
Description: The Coronavirus-Like Particle (CoVLP) COVID-19 Vaccine is composed of recombinant spike (S) glycoprotein expressed as virus-like particles (VLPs).~The 3.75 µg dose of CoVLP will be administered with the adjuvant AS03 (manufactured by GlaxoSmithKline).
Study: NCT06717048

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repeated Low-level Red-light
Description: In addition to single vision spectacle lenses (SVS) with power for correcting distance refraction, the subjects used the prescribed power low-intensity red light treatment instrument for the prescribed number of treatments from Monday to Friday, with a 3-minute interval of 4 hours.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Red LED
Description: In addition to SVS with power for correcting distance refraction, red LED will be performed twice per school day with an interval of at least 4 hours, each treatment last 3 minutes.
Study: NCT06718478

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SakuraBead Resorbable Microspheres
Description: Temporary Embolization of Genicular Arteries using SakuraBead Resorbable Microspheres
Study: NCT06716827

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: In-office bleaching system
Description: As the whitening agent, an in-office bleaching system containing 35% hydrogen peroxide (Whiteness HP, FGM) was chosen. The gingiva was isolated using an isolation material (Opaldam, Ultradent Products Inc.), which was light-cured with a standard curing light. The whitening gel was applied to the labial surfaces of the maxillary incisors and canines with a 1mm thickness and left for 20 minutes. After cleaning the teeth with an aspiration tip, the whitening procedure was repeated.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laser-assisted bleaching
Description: Whitening was performed 10 days prior to treatment, with laser treatment applied without removing brackets in the fixed appliance group and without cleaning attachments in the aligner group. The laser was applied to the buccal surface of the teeth with a 1mm distance for 30 seconds in three applications. After a 10-minute rest, the laser procedure was repeated.
Study: NCT06050967

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Enzyme replacement therapy for Gaucher disease in combination with altus care application
Description: In coordination with the patient's treating physician and the home treating nurse, an individualized treatment plan was prepared for each patient within a pre-defined range of minimal and maximal once in two weeks enzyme replacement therapy dosages and timing frames for its administration. Per protocol, the patient's monthly dose was not changed, but each dose and the timing of administration was changed randomly using the app.
Study: NCT05225220

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
Description: Electrode clip will be placed on the left ear.
Study: NCT05991674

Intervention type: DIAGNOSTIC_TEST
Intervention: patch test for diagnosing allergic contact dermatitis
Description: European Baseline Series (EBS) System of allergens
Study: NCT05534035

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PTX-COVID19-B
Description: The vaccine product, PTX-COVID19-B, is a preservative-free, sterile mRNA-lipid nanoparticle (mRNA-LNP) dispersion in an aqueous cryoprotectant buffer intended for IM injection.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaxzevria®
Description: The AstraZeneca COVID-19 Vaccine is a colorless to slightly brown solution, clear to slightly opaque with a pH of 6.6. One dose (0.5 ml) contains: COVID-19 Vaccine (ChAdOx1-S\* recombinant) 5 × 1010 viral particles (vp) (corresponding to not less than 2.5 × 108 ifu).
Study: NCT04806516

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Summit RC+S System with ECoG Paddles
Description: Summit RC+S System with ECoG Paddles consists of:~* Olympus RC+S implantable pulse generator (IPG), Model B35300R: 2 per subject x 5 subjects = 10 units~* Extension Leads, Model 37087: 2 per subject X 5 subjects = 10 units~* DBS Leads, Model 3387: 2 per subject X 5 subjects = 10 units~* Patient Therapy Manager (PTM), Model 4NR009: 1 per subject x 5 subjects = 5 units~* Recharge Therapy Manager (RTM), Model 97755: 1 per subject x 5 subjects = 5 units~* Clinician Telemetry Module (CTM), Model 4NR011: 1 per subject x 5 subjects = 5 units~* Research Lab Programmer (RLP), Model 4NR010: 1 unit~* Research Software Development Kit (RDK), Model 4NR013: 2 units~* Subdural Quadripolar Paddle Lead, Model 09130: 2 per subject x 5 subjects = 10 units

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: One Month Blinded Discontinuation Period:
Description: The subject and Independent Evaluators are blinded to timing of discontinuation. In all cases, the sequence will be as follows in one-week segments: 100% Active, 50% Active, Sham and Sham. Subjects will be seen weekly. Amplitude will be reduced by 50% at start of week 2 and turned off at start of week 3. Subjects will be told that DBS will be discontinued at some point during the 4 weeks. The purpose of the 50% initial reduction is to minimize rebound effects. The programmer (not the PI in this case) will be open to the design and perform sham activation as described previously. Relapse is defined as a 25% increase of the Y-BOCS over two consecutive visits compared to discontinuation baseline.
Study: NCT06275243

Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Kit Buccal swab collection & stabilization de Canvax®
Description: Assessment of ApoE variant in saliva samples as a potential biomarker for Alzheimer's disease.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Kit Buccal swab collection & stabilization de Canvax®
Description: Assessment of ApoE variant in saliva samples as a potential biomarker for Alzheimer's disease.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cholesterol levels according to ApoE Genotype
Description: Enhancing the quality of life of study participants by investigating cholesterol levels based on their ApoE genotype.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Assessing cardiovascular risk factors in all participants
Description: Through individual interviews, record cardiovascular factors and assess their correlation with Alzheimer's disease.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Assessing cardiovascular risk factors in all participants
Description: Through individual interviews, record cardiovascular factors and assess their correlation with Alzheimer's disease.
Study: NCT05401474

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Flow Nasal Cannula at 30L/min
Description: Flow will be set at 30L/min, FiO2 will be adjusted manually to maintain SpO2within the target range

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Flow Nasal Cannula at 45L/min
Description: Flow will be set at 45L/min, FiO2 will be adjusted manually to maintain SpO2within the target range

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Flow Nasal Cannula at 60L/min
Description: Flow will be set at 60L/min, FiO2 will be adjusted manually to maintain SpO2within the target range
Study: NCT05393076

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linerixibat
Description: Linerixibat dose and administration as per study intervention.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linerixibat
Description: Linerixibat dose and administration as per study intervention.
Study: NCT05614713

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Selected physical therapy program
Description: Gait training and balance training

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Modified physical therapy program to increase sensory input
Description: Gait training and balance training using sensory stimulating matts
Study: NCT06127706

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: twin vaginal delivery simulation
Description: skill test after formal lecture and simulation in group 1 and after digital learning only

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: twin vaginal delivery simulation
Description: skill test after formal lecture and simulation in group 1 and after digital learning only