TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05591937

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-Guided Online Prevention
Description: An online wellness program that contains self-guided online CBT prevention strategies with demonstrated efficacy for depression and anxiety in college samples. Participants can learn skills for coping with common stressful experiences and build resilience at their own pace.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coach-Guided Online Cognitive Behavioral Therapy
Description: An online digital therapy program that consists of online CBT modules supported by coaches through video chats. The modules are evidence-based and formatted into a unified approach for depression, anxiety and worry, panic, social anxiety, trauma and sleep dysregulation (developed as part of the University of California, Los Angeles (UCLA) Depression Grand Challenge). Lessons are designed to respond to participants' specific symptoms. Participants can access the system through any personal device (phone, tablet or computer) and speak to a certified student coach through remote video chat.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Coach-Guided Online Cognitive Behavioral Therapy
Description: An online digital therapy program that consists of online CBT modules supported by coaches through video chats. The modules are evidence-based and formatted into a unified approach for depression, anxiety and worry, panic, social anxiety, trauma and sleep dysregulation (developed as part of the University of California, Los Angeles (UCLA) Depression Grand Challenge). Lessons are designed to respond to participants' specific symptoms. Participants can access the system through any personal device (phone, tablet or computer) and speak to a certified student coach through remote video chat.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Clinician-Delivered Psychological and Psychiatric Care
Description: Evidence-based clinician-delivered CBT modules. Participants are connected to a team of clinicians who will evaluate participants' specific symptoms and create an individualized and tailored treatment plan. Treatment will include weekly sessions delivered through telehealth, and if deemed appropriate, participants may also have medication appointments.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Clinician-Delivered Psychological and Psychiatric Care
Description: Evidence-based clinician-delivered CBT modules. Participants are connected to a team of clinicians who will evaluate participants' specific symptoms and create an individualized and tailored treatment plan. Treatment will include weekly sessions delivered through telehealth, and if deemed appropriate, participants may also have medication appointments.
Study: NCT04895592

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resection
Description: Undergo surgical resection

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: Undergo SRS

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: Undergo SRS
Study: NCT05893420

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: eCARTv5 clinical deterioration monitoring
Description: eCART is a predictive analytic used for the identification of acute clinical deterioration built upon more than a decade of ongoing scientific research and chronicled in numerous peer-reviewed publications. eCART draws upon readily available patient data from the EHR, rapidly quantifies disease severity, and predicts the likelihood of critical illness onset.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care control
Description: Standard of care is the health system's clinical best practices and workflows for identifying high-risk patients for clinical deterioration, including other tools already built into the electronic health record (EHR). Hospitals that do not implement eCARTv5 will be compared as a control against hospitals that do implement eCARTv5.
Study: NCT06528236

Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence model
Description: Using the artificial intelligence model to diagnosis benign, borderline, and malignant ovarian masses.

Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence model
Description: Using the artificial intelligence model to diagnosis benign, borderline, and malignant ovarian masses.

Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence model
Description: Using the artificial intelligence model to diagnosis benign, borderline, and malignant ovarian masses.
Study: NCT05605106

Intervention type: DIAGNOSTIC_TEST
Intervention: speckle tracking echocardiography
Description: Speckle tracking is a recent development in image processing that uses proprietary software to automatically determine the movements of these points, which appear sonographically as speckles, within the myocardium over time. Tracking the movements of these speckles throughout the cardiac cycle yields positive values when the two points are moving away from one another, as in diastole, and negative values when they are moving towards one another, as in systole

Intervention type: DIAGNOSTIC_TEST
Intervention: speckle tracking echocardiography
Description: Speckle tracking is a recent development in image processing that uses proprietary software to automatically determine the movements of these points, which appear sonographically as speckles, within the myocardium over time. Tracking the movements of these speckles throughout the cardiac cycle yields positive values when the two points are moving away from one another, as in diastole, and negative values when they are moving towards one another, as in systole

Intervention type: PROCEDURE
Intervention: Percutaneous coronary intervention
Description: Percutaneous coronary intervention refers to a family of minimally invasive procedures used to open clogged coronary arteries (those that deliver blood to the heart). By restoring blood flow, the treatment can improve symptoms of blocked arteries, such as chest pain or shortness of breath.

Intervention type: PROCEDURE
Intervention: Percutaneous coronary intervention
Description: Percutaneous coronary intervention refers to a family of minimally invasive procedures used to open clogged coronary arteries (those that deliver blood to the heart). By restoring blood flow, the treatment can improve symptoms of blocked arteries, such as chest pain or shortness of breath.
Study: NCT05561023

Intervention type: DRUG
Group type: OTHER
Intervention: Hawthorn red pigment
Description: For patients with refractory cancer pain who meet the enrollment conditions, on the basis of the clinician's normal adjustment of the analgesic regimen (the initial adjustment is the first day), the dose ramp up study of Hawthorn red pigment was started on the third day. The Hawthorn red dose group includes 10 tablets → 15 tablets → 20 tablets / time, orally, twice a day.~3 + 3 dose escalation scheme
Study: NCT06100679

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Responsible Engaged and Loving (REAL) Fathers Initiative
Description: REAL Fathers is a multilevel norms-shifting intervention among: young fathers (ages 16-25 whose oldest child is under the age of 3); couple dyads (fathers and wives); mentoring dyads and groups; and communities. Respected men in the community are identified by participating young fathers, their partners and community members to become mentors. Mentors participate in a training and mentor young fathers through home and group sessions on conflict resolution, non-violent discipline, family planning, and couple communication. Mentoring is supplemented with a monthly poster campaign designed to reinforce messages from the home and group mentoring sessions and a community celebration. REAL Fathers aims to build positive partnerships and parenting practices among young fathers to: 1) reduce incidence of intimate partner violence; 2) reduce harsh physical punishment of children; 3) improve early childhood development; 4) decrease unmet need for family planning.
Study: NCT04804163

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: telesurgery by domestic robot
Description: telesurgery of the upper urinary disease by domestic robot
Study: NCT04711642

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: The study will include three arms, one non interventional and 2 interventions. The intervention arms will include two commercially available sodium hyaluronate 0.1% (Systane ultra plus and Hylo-comod)
Description: All groups will receive a topical steroid-antibiotic for 3 weeks. The study groups will be also prescribed eye drops containing sodium hyaluronate 0.1% from the postoperative day 7 for 4 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: The study will include three arms, one non interventional and 2 interventions. The intervention arms will include two commercially available sodium hyaluronate 0.1% (Systane ultra plus and Hylo-comod)
Description: All groups will receive a topical steroid-antibiotic for 3 weeks. The study groups will be also prescribed eye drops containing sodium hyaluronate 0.1% from the postoperative day 7 for 4 weeks.
Study: NCT04629534

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose Cholecalciferol
Description: Mothers in experimental group will receive 6,000 IU of vitamin D in addition to their prenatal vitamin, daily for 3 months. Infants in this group will receive placebo vitamin D drops

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cholecalciferol
Description: Mothers in placebo control group will receive 600 IU of vitamin D in the form of their prenatal vitamin along with placebo vitamin D. Infants of the mothers in this group will receive standard 400 IU of vitamin D
Study: NCT06207058

Intervention type: DRUG
Intervention: Baloxavir Marboxil
Description: Subjects testing positive for influenza will receive a dose of Baloxavir Marboxil orally, according to the dosing indicated in the package insert.
Study: NCT04157062

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: During the rTMS session, an electromagnetic coil is placed against the subjects scalp. The electromagnet painlessly delivers a magnetic pulse that stimulates nerve cells in the region of the brain involved in memory and thinking.
Study: NCT05892848

Intervention type: DIAGNOSTIC_TEST
Intervention: serum ostecalcin,serum sclerostin and parathroid profile
Description: evaluation of bone turnover markers in blood

Intervention type: DIAGNOSTIC_TEST
Intervention: serum ostecalcin,serum sclerostin and parathroid profile
Description: evaluation of bone turnover markers in blood
Study: NCT05435378

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin B3 100 MG Oral Tablet
Description: After the non surgical treatment and the oral hygiene instructions The systemically administered vitamin B3 capsules will then given to the patients under the previously mentioned dosage.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: vitamin B9
Description: After the non surgical treatment and the oral hygiene instructions the systemically administered vitamin B9 capsules will then given to the patients under the previously mentioned dosage.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: After the non surgical treatment and the oral hygiene instructions The systemically administered placebo capsules will then given to the patients under the previously mentioned dosage.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: full mouth non surgical periodontal treatment
Description: full mouth scaling and debridement will be done by the primary investigator using ultrasonic scaler and periodontal curettes. After the non surgical treatment patients will be given oral hygiene instructions where they will be instructed to brush twice daily and shown how to brush using the horizontal scraping technique they will also be instructed to use the dental floss and shown how to use it.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: full mouth non surgical periodontal treatment
Description: full mouth scaling and debridement will be done by the primary investigator using ultrasonic scaler and periodontal curettes. After the non surgical treatment patients will be given oral hygiene instructions where they will be instructed to brush twice daily and shown how to brush using the horizontal scraping technique they will also be instructed to use the dental floss and shown how to use it.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: full mouth non surgical periodontal treatment
Description: full mouth scaling and debridement will be done by the primary investigator using ultrasonic scaler and periodontal curettes. After the non surgical treatment patients will be given oral hygiene instructions where they will be instructed to brush twice daily and shown how to brush using the horizontal scraping technique they will also be instructed to use the dental floss and shown how to use it.
Study: NCT05402995

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irrisept (Irrigation Solution)
Description: Irrisept Antimicrobial Wound Lavage is intended for mechanical cleansing and removal of debris, dirt and foreign materials, including microorganisms from wounds.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irrisept (Irrigation Solution)
Description: Irrisept Antimicrobial Wound Lavage is intended for mechanical cleansing and removal of debris, dirt and foreign materials, including microorganisms from wounds.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Saline
Description: Saline irrigation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Saline
Description: Saline irrigation
Study: NCT06185699

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: standard superficial skin biopsy (SSSB)
Description: standard superficial skin biopsy (SSSB) was applied to the face that was wiped with dry sterile gauze after dropping cyanoacrylate by marking 1 cm2 area on the slide that was wiped with dry sterile gauze from 3 areas of the face, right cheek, nose and the mid-forehead. After the slide was left for 60 seconds and slowly removed from the face, immersion oil was dripped onto the slide and covered with a coverslip, and Demodex mites were counted first under the light microscope at x10 and then x20 magnification (Demodex foliculorum and brevis were not differentiated). The process was repeated for each region.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: standard superficial skin biopsy (SSSB)
Description: standard superficial skin biopsy (SSSB) was applied to the face that was wiped with dry sterile gauze after dropping cyanoacrylate by marking 1 cm2 area on the slide that was wiped with dry sterile gauze from 3 areas of the face, right cheek, nose and the mid-forehead. After the slide was left for 60 seconds and slowly removed from the face, immersion oil was dripped onto the slide and covered with a coverslip, and Demodex mites were counted first under the light microscope at x10 and then x20 magnification (Demodex foliculorum and brevis were not differentiated). The process was repeated for each region.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: standard superficial skin biopsy (SSSB)
Description: standard superficial skin biopsy (SSSB) was applied to the face that was wiped with dry sterile gauze after dropping cyanoacrylate by marking 1 cm2 area on the slide that was wiped with dry sterile gauze from 3 areas of the face, right cheek, nose and the mid-forehead. After the slide was left for 60 seconds and slowly removed from the face, immersion oil was dripped onto the slide and covered with a coverslip, and Demodex mites were counted first under the light microscope at x10 and then x20 magnification (Demodex foliculorum and brevis were not differentiated). The process was repeated for each region.
Study: NCT05690178

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep Tissue Massage
Description: The Deep Tissue Massage lasted 45 minutes. The entire therapy included 4 treatments over a period of 2 weeks. The interval between treatments was 3 days. The conducted therapy included techniques for: quadratus lumborum muscle, erector spinae muscle, thoracolumbar fascia, iliopsoas muscle. All techniques were performed on both sides of the patient's body.
Study: NCT05700851

Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Immuno-nutrition supplement
Description: Oral Impact® is a powdered oral nutritional supplement that contains a unique combination of ingredients with immuno-modulating properties, namely omega-3 fatty acids, arginine and nucleotides, as well as soluble fibre.
Study: NCT05602025

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Depemokimab
Description: Depemokimab will be administered via a SSD or autoinjector.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Depemokimab
Description: Depemokimab will be administered via a SSD or autoinjector.
Study: NCT06294327

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Reactive static air support surfaces
Description: * Repose® Mattress~* Repose® Cushion~* Repose® Wedge~* Repose® Foot Protectors
Study: NCT06022666

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Geriatric assessment
Description: Geriatric assessment through PATH clinic which includes an evaluation of comorbidities, health trajectory and baseline frailty as well as conducting an in-depth discussion with the patient on how frailty stage impacts decision-making about surgery in order to co-develop a care plan.
Study: NCT04769570

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: interscalene brachial plexus block
Description: Single shot ultrasound guided interscalene brachial plexus block will be performed preoperatively to patients.Patient-controlled analgesia (PCA) with morphine will be used for postoperative analgesia.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: suprascapular nerve block
Description: Single shot ultrasound guided interscalene brachial plexus block and Suprascapular nerve block will be performed preoperatively to patients.Patient-controlled analgesia (PCA) with morphine will be used for postoperative analgesia.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group Control
Description: consist of the patient group without any procedure.
Study: NCT06164665

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pioglitazone 15mg
Description: Pioglitazone (PIO) will be administered as a 15 mg oral dose per day for 5 days

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 100% microcrystalline cellulos
Study: NCT06184607

Intervention type: OTHER
Intervention: Distance from contact point to attachment level
Description: A periodontal probe will be used to measure distance between contact point to attachment level in maxillary central incisors
Study: NCT05694455

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Starling Stroke Volume (Starling SV)- Passive Leg Raise
Description: All septic patients will have a passive leg raise performed with the assistance of an Starling SV device to look at Stroke Volume change. This will be performed at admission and 4 hours after admission. This intervention will not be performed on healthy controls

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Starling Stroke Volume (Starling SV)- Passive Leg Raise
Description: All septic patients will have a passive leg raise performed with the assistance of an Starling SV device to look at Stroke Volume change. This will be performed at admission and 4 hours after admission. This intervention will not be performed on healthy controls

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Microscan Sublingual Microscopy
Description: All septic patients will have sublingual microscopic images performed at admission, 8-16 hours, 48 hours and 72 hours. Control patients will have a sublingual microscope imaging performed after intubation for the elective procedure. This is a process of a 2cm probe tip gently placed on patients' mouth and 3 different images of 5-8 seconds are recorded.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Venous Excess Ultrasound Scoring (VExUS)
Description: All septic Patients will have this performed on all patients at admission, 8-16 hours, 48 hours and 72 hours. Ultrasound images and blood flow waves will be collected of the Inferior Vena Cava diameter, hepatic vein, portal vein, renal veins and scored using the Venous Excess Ultrasound (VExUS scale). Healthy controls will not have ultrasound performed

Intervention type: OTHER
Group type: OTHER
Intervention: Urine Collection
Description: The urine assay is collected passively from the patient will be ran through a Dimethylmethylene blue (DMMB assay)- could provide future beneficial information to resuscitation efforts. This will be performed on all septic patients at admission, 8-16 hours, 48 hours and 72 hours. Urine will be collected on healthy controls at time of intubation for elective procedure.

Intervention type: OTHER
Group type: OTHER
Intervention: Urine Collection
Description: The urine assay is collected passively from the patient will be ran through a Dimethylmethylene blue (DMMB assay)- could provide future beneficial information to resuscitation efforts. This will be performed on all septic patients at admission, 8-16 hours, 48 hours and 72 hours. Urine will be collected on healthy controls at time of intubation for elective procedure.
Study: NCT06025539

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal-assisted resilience training
Description: Participants take part in 12 sessions (120 minutes each), each session focuses on a topic that is related to resilience. The intervention takes part outdoors on a farm, and includes interactions with several different animals. The training takes place in small groups, and includes exercises, observations, and discussions.
Study: NCT06581978

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Whole-Body Vibration Intervention
Description: Whole-Body Vibration Intervention

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exercise Intervention Group
Description: Traditional Chinese medical exercises training
Study: NCT06130904

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Academic detailing
Description: Eligible dentists/oral surgeons will have one visit (30 minutes or less) at the dentist's office. During the initial visit, the detailers will discuss the evidence against routine opioid prescribing to adolescents and young adults for most common surgeries performed by dentists and oral surgeons, the harms of dental opioid exposure in adolescents and young adults, and the benefits and feasibility of relying on non-opioids as a first line option for routine dental procedures among adolescents and young adults. A survey will be completed to assess the satisfaction regarding the intervention. A professionally designed packet of information on reducing use of opioids for routine procedures will also be given.~There may also be a second optional follow-up visit conducted virtually for any participants that wish to discuss further with the detailer. The second visit may occur any time between the initial visit and March 31, 2024.