TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04999254

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical treatment
Description: Medical treatment will be based on functional treatment and the doctor will prescribe the RICE protocol. For this, the patient will have to :~* place an ice pack on the sprain~* apply sports rest for three weeks~* compress the sprain with a compression stocking when standing in order to prevent phlebitis. In addition, to avoid this complication, the doctor will prescribe an anticoagulant.~* raise the foot with crutches during the day~* elevate the foot at night or when doing an activity in a sitting position, using a cushion for example.~In addition, the doctor will prescribe anti-inflammatory drugs to ease the pain and physiotherapy to establish proprioception, muscle strength, joint range and dynamic postural balance of the sprain.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Medical treatment
Description: Medical treatment will be based on functional treatment and the doctor will prescribe the RICE protocol. For this, the patient will have to :~* place an ice pack on the sprain~* apply sports rest for three weeks~* compress the sprain with a compression stocking when standing in order to prevent phlebitis. In addition, to avoid this complication, the doctor will prescribe an anticoagulant.~* raise the foot with crutches during the day~* elevate the foot at night or when doing an activity in a sitting position, using a cushion for example.~In addition, the doctor will prescribe anti-inflammatory drugs to ease the pain and physiotherapy to establish proprioception, muscle strength, joint range and dynamic postural balance of the sprain.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: osteopathic treatment
Description: Each patient will be treated as a whole and within a time limit of 45 minutes. The consultation will start with a medical history followed by medical tests. Then, the osteopath will perform osteopathic tests and manual treatment.
Study: NCT04739371

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin, Regular, Human
Description: The spray will last a few seconds and then the participant will be asked to sniff to aid the drug into the nose. The device (i.e. ViaNase) is an atomizer that uses its patented technology that turns the liquid into a fine mist of droplets to facilitate the drug along the nose to brain pathway. Each nostril will receive this administration 2 times for a total of 40 IUs or 0.4 mL of liquid.
Study: NCT05177094

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3526318
Description: Administered orally

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally
Study: NCT05510453

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-intensity online intervention (LiON)
Description: The LiON in the current study is comprised of three core modules identified to be core areas of stress and needs of participants based on clinical experiences of the research team. The three modules include (1) stress management, (2) sleep and relaxation, and (3) problem-solving skills.~Each module consists of four 1-on-1 sessions which will be conducted through online platforms (such as Zoom) that lasts for 45 minutes. Participants will attend these sessions once a week.~The control group will receive the intervention after a waiting period of 4 weeks.

Intervention type: OTHER
Group type: OTHER
Intervention: Low-intensity online intervention (LiON)
Description: The LiON in the current study is comprised of three core modules identified to be core areas of stress and needs of participants based on clinical experiences of the research team. The three modules include (1) stress management, (2) sleep and relaxation, and (3) problem-solving skills.~Each module consists of four 1-on-1 sessions which will be conducted through online platforms (such as Zoom) that lasts for 45 minutes. Participants will attend these sessions once a week.~The control group will receive the intervention after a waiting period of 4 weeks.
Study: NCT05970458

Intervention type: OTHER
Intervention: Quality of life assessment
Description: EQ5D-5L and Stoma QoL

Intervention type: OTHER
Intervention: Quality of life assessment
Description: EQ5D-5L and Stoma QoL

Intervention type: OTHER
Intervention: Quality of life assessment
Description: EQ5D-5L and Stoma QoL
Study: NCT06214312

Intervention type: DIAGNOSTIC_TEST
Intervention: Lung Ultrasounds
Description: An ultrasound exam of the lungs to identify possible areas of atelectasis.

Intervention type: DIAGNOSTIC_TEST
Intervention: Lung Ultrasounds
Description: An ultrasound exam of the lungs to identify possible areas of atelectasis.
Study: NCT05628844

Intervention type: PROCEDURE
Intervention: Continuous enteral feeding
Description: Enteral nutrition by continuous infusion for 10 hrs at a dose corresponding to 25 kcal/kg body weight/day

Intervention type: PROCEDURE
Intervention: Continuous enteral feeding
Description: Enteral nutrition by continuous infusion for 10 hrs at a dose corresponding to 25 kcal/kg body weight/day
Study: NCT04739371

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The spray will last a few seconds and then the participant will be asked to sniff to aid the saline into the nose. The device (i.e. ViaNase) is an atomizer that uses its patented technology that turns the liquid into a fine mist of droplets to facilitate the drug along the nose to brain pathway. Each nostril will receive this administration 2 times for a total of 40 IUs or 0.4 mL of liquid.
Study: NCT05153889

Intervention type: OTHER
Group type: OTHER
Intervention: Hospitalized in Intensive care unit
Description: Patient hospitalized in Intensive care unit with ECG monitoring

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hospitalized in General cardiology ward
Description: Patient hospitalized in General cardiology ward without ECG monitoring. patients randomized in this group will not be hospitalized in intensive care unit unless an event require intensive care unit monitoring.
Study: NCT05640076

Intervention type: OTHER
Intervention: 24/7 Telephonic Palliative Care Service availability
Description: Metropolitan Palliative Care Service-implemented 24/7 telephonic availability service for the patients, their relatives, the EMS and Primary Care physicians taking care of them.~After consultation, if the information and medical suggestions are not sufficient, an urgent ambulatory or home visit could be planned.

Intervention type: OTHER
Intervention: 24/7 Telephonic Palliative Care Service availability
Description: Metropolitan Palliative Care Service-implemented 24/7 telephonic availability service for the patients, their relatives, the EMS and Primary Care physicians taking care of them.~After consultation, if the information and medical suggestions are not sufficient, an urgent ambulatory or home visit could be planned.

Intervention type: OTHER
Intervention: 24/7 Telephonic Palliative Care Service availability
Description: Metropolitan Palliative Care Service-implemented 24/7 telephonic availability service for the patients, their relatives, the EMS and Primary Care physicians taking care of them.~After consultation, if the information and medical suggestions are not sufficient, an urgent ambulatory or home visit could be planned.
Study: NCT04825522

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin
Description: During spinal surgery, participants will receive intrawound vancomycin powder in their wound before closure.
Study: NCT06090240

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MI-based ACP intervention
Description: Motivational Interviewing on Advance Care Planning Intervention: Dyads of older adults and family caregivers will receive three MI-based ACP counselling sessions: (1) a preparatory session, (2) motivation session, and (3) planning session. The preparatory session will take 10-15 minutes, and the following two sessions in weeks 2 and 3 will last 30-45 minutes each. Before each session, the nurse interventionist will first assess the dyad's readiness to engage in ACP based on the state of change algorithm. Participants who have never thought about ACP will be in the pre-contemplation state, those who are willing to discuss EOL care and preferences to be in the contemplation state, those ready to talk about EOL planning to be in the preparation state, and those in the action state have a confirmed action plan on signing up their ADs. Readiness-based ACP goals will be established, and state-matched MI counseling will be customized for each participant.
Study: NCT06301360

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet based Emotional Awareness and Expression Therapy (I-EAET)
Description: In I-EAET with therapist support, the therapist and participants communicate asynchronous using written messages. The therapist gives feedback each week on home-work assignments and is available on demand for support.~In I-EAET without therapist support, the participants works with home-work assignments on their own and only have technical support.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Internet based Emotional Awareness and Expression Therapy (I-EAET)
Description: In I-EAET with therapist support, the therapist and participants communicate asynchronous using written messages. The therapist gives feedback each week on home-work assignments and is available on demand for support.~In I-EAET without therapist support, the participants works with home-work assignments on their own and only have technical support.
Study: NCT05111314

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Gallium Ga 68 Gozetotide
Description: Given IA

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hepatic Artery Embolization
Description: Undergo hepatic artery embolization

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography and Computed Tomography Scan
Description: Undergo PET/CT scan
Study: NCT05983640

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video
Description: Just in time training video on hands only CPR

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: AHA course
Description: AHA Heartsaver CPR course
Study: NCT04751721

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CoronoVac Vaccine
Description: CoronaVac vaccines will be inoculated in 2 doses with an interval of 24 days.
Study: NCT04999787

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542
Description: HSK21542-0.3 μg/kg，HSK21542-0.6 μg/kg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT05727644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0194-0499
Description: Participants will receive a single subcutaneous injection of 30 mg NNC0194-0499.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NNC0194-0499
Description: Participants will receive a single subcutaneous injection of 30 mg NNC0194-0499.
Study: NCT05082480

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyaluronic acid (HA)
Description: Hyaluronic acid (HA)

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline
Study: NCT06451783

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Chinese medicine combined with manipulation treatment
Description: The specific procedure involves administering the Shengyu Decoction, which consists of the following herbs:~* Shu Di Huang 20 grams~* Bai Shao 15 grams~* Dang Gui 15 grams~* Chuan Xiong 8 grams~* Ren Shen 20 grams~* Huang Qi 18 grams One dose is taken per day, and a course of treatment consists of five weeks. Add manipulation of massage：~  * Press and grasp the affected limb three times；~    * Five-finger five-acupoint pressing method；~      * Point pressing on Zusanli (ST36) and Sanyinjiao (SP6)；~        * grasp the interior method to treat the calf three times；~          ⑤ Apply rolling technique around the knee joint；~          ⑥ Knead and straighten the standing tendon (the lateral muscle of the calf)；~          ⑦ Six-finger six-acupoint pressing method；~          ⑧ Push and pull the patella to flex and extend the knee joint；~          ⑨ Knee joint reunion and smooth dispersion method.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Celecoxib capsule
Description: Oral Celecoxib Capsules, 200mg per dose, once daily after lunch.
Study: NCT05609539

Intervention type: DEVICE
Intervention: Endovascular Aortic Repair (EVAR)
Description: Techniques for delivery and deployment of the standard device have been well described by different papers, but for the prototype some attention is required.~Once the device was advanced at the level of the lowest RA the C-Arm has been moved to correct the parallax effect and positioned orthogonally to the origin of the artery. This procedure permits perfectly matching the scallop with the artery takeoff.~A selective angiogram was performed to assure the patency of the lower RA. After the deployment of the main body proper iliac extensions were delivered to completely exclude the aneurysm as standard practice.
Study: NCT05504772

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.

Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.
Study: NCT05814445

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromuscular exercise program
Description: Participants will complete a neuromuscular program during 22 weeks. The program consist of isotonic open and closed kinetic chain exercises for the hip and knee, and training to improve hip and knee muscles strength, proprioception, and core stability.
Study: NCT05813496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alpha-Lipoic Acid (ALA)
Description: Oral tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Microcrystalline cellulose (Ph 101) 427.5 mg, Magnesium stearate 71.25 mg, Sodium laurayl sulphate 6 mg, Croscarmellose sodium 11.25 mg, Silica, colloid anhydrous 11.25 mg, and Purified talc 30 mg.
Study: NCT05814445

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Institutional exercise program
Description: Participants will complete an institutional exercise program during 22 weeks. The program consist of isotonic open and closed kinetic chain exercises for the hip and knee, and concentric and eccentric knee exercises.
Study: NCT05690516

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wearing face masks
Description: Participants are asked to wear face masks in public spaces.
Study: NCT05884619

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual-target deep brain stimulation
Description: DBS electrodes will be implanted into the ALIC and the NAcc, electric stimulation of those areas are used to treat alcohol use disorder and to evaluate the efficacy and safety of DBS system.
Study: NCT05663411

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508
Description: SHR6508

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508
Description: SHR6508

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cinacalcet
Description: Cinacalcet
Study: NCT05316428

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TPN171H tablet plus alcohol
Description: 10 mg TPN171H tablet QD plus 0.5 g/kg alcohol

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: alcohol
Description: 0.5 g/kg alcohol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TPN171H tablet
Description: 10 mg TPN171H tablet QD
Study: NCT06056817

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Calyan Pacemaker
Description: The Calyan pacemaker is a device designed for implantation in the chest below the xiphoid process, and includes a FlexArm containing stimulation and sensing electrodes. The Calyan pacemaker is implanted using a set of delivery tools and clipped onto the xiphoid process; the FlexArm electrodes are oriented to make contact with the pericardial surface of the heart. Pacing parameters are adjusted wirelessly with a tablet-based programmer that communicates with the Calyan pacemaker via secure Bluetooth.
Study: NCT05926570

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cinacalcet
Description: calcimimetic
Study: NCT05886101

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Education
Description: Health education will be provided to the intervention group on health literacy, self care, productivity improvement
Study: NCT06099340

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: muscle-strengthening program
Description: a muscle-strengthening program applied to the ankle muscles (triceps surae and dorsal flexors) in physiotherapy, as a complement to conventional rehabilitation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: muscle-strengthening program
Description: a muscle-strengthening program applied to the ankle muscles (triceps surae and dorsal flexors) in physiotherapy, as a complement to conventional rehabilitation
Study: NCT05358860

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sofwave
Description: The Sofwave System, comprised of an applicator and a console, generates high intensity, non-focused ultrasonic energy which can be delivered percutaneously to tissues.
Study: NCT05069961

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ESPB
Description: Ropivacaine is injected near the nerves in the back

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TEA
Description: Bupivacaine is injected into the space around the spinal cord.
Study: NCT05105945

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery
Description: Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery dissects, dissociates and removes the esophagus in the mediastinum through an inflatable endoscopy. Detailed surgical procedures and related instructions have been published in Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery for Radical Esophagectomy Is an Effective and Safe Treatment for Esophageal Cancer J Gastrointest Surg. 2019 Aug;23(8):1533-1540. doi: 10.1007/s11605-018-04069-w. Epub 2019 Jan 11.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Thoracoscopy Combined With Laparoscopic Surgery
Description: Patients will receive a standardized thoracoscopy and laparoscopy combined radical esophageal cancer surgery
Study: NCT06217224

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preventive photobiomodulation Therapy (PBMT)
Description: The application of preventive TLBP will be performed with a laser device containing an aluminum phosphide and indium gallium diode (InGaAlP) emitting radiation in the red region of the electromagnetic spectrum (660 nm) with a power of 100mW and a beam area of 0.03 cm2 . An energy of 1J/point and an energy density of 33.3 J/cm2/point were determined, which will be applied punctually, with a distance between the points of 1cm, for 10s per point, totaling 9 points per region.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preventive photobiomodulation Therapy (PBMT)
Description: The application of preventive TLBP will be performed with a laser device containing an aluminum phosphide and indium gallium diode (InGaAlP) emitting radiation in the red region of the electromagnetic spectrum (660 nm) with a power of 100mW and a beam area of 0.03 cm2 . An energy of 1J/point and an energy density of 33.3 J/cm2/point were determined, which will be applied punctually, with a distance between the points of 1cm, for 10s per point, totaling 9 points per region.
Study: NCT03948022

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dydrogesterone 10Mg Tablet (duphaston)
Description: 40 mg daily oral tablets

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Progesterone 50Mg/mL Oil
Description: 100 mg daily intramuscular injections

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Crinone 8% Vaginal Gel
Description: 180 mg daily vaginal gels
Study: NCT04657965

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LMP1 CAR T-cells
Description: Each subject receive LMP1 CAR T-cells by intravenous infusion