TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04804553

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apremilast
Description: Participants will receive apremilast orally.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Apremilast
Description: Participants will receive apremilast orally.
Study: NCT06582693

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Refer2Quit
Description: The Refer2Quit intervention consists of automatic connection to the adult participant's choice of any or all of four evidence-based tobacco treatment options (varenicline, NRT, quitline, and/or smokefreeTXT), as well as motivational counseling provided by the study team. Supportive and motivational text messaging is also included in the intervention to connect or reconnect adult participants to treatments as needed. Text messaging and support would also focus on supporting appropriate use of NRT and/or varenicline if indicated.
Study: NCT06110156

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient-tailored deprescribing assessment and intervention
Description: Patients are identified for enrollment via a risk prediction model and enrolled in a pharmacist-led polypharmacy clinic. The pharmacist will conduct a comprehensive medication review, which will include: medication reconciliation, assessment of patient risk factors (clinical, socioeconomic), identification of potentially inappropriate medications, identification of potential prescribing omissions, shared decision-making with the patient and/or caregiver, and confirmation of the results of the comprehensive medication review with the primary care clinician. Once the primary care clinician has approved the recommendations, the pharmacist will make the appropriate changes to the medication regimen, will provide tailored medication education and counseling (including Motivational Interviewing) and will follow-up with the patient at least once per month via video visit or phone to assess side effects, adverse effects, and provide support.
Study: NCT04804553

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive the matching placebo orally.
Study: NCT06585787

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KarXT
Description: Specified dose on specified days
Study: NCT06405737

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intranasal oxytocin
Description: Subject assigned to receive intranasal administration of oxytocin (24 IU).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intranasal placebo
Description: Subjects assigned to receive intranasal administration of placebo (24 IU).
Study: NCT05409053

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: open reduction
Description: the displaced fractures will be treated with open reduction so as to achieve the near anatomical alignment

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: open reduction
Description: the displaced fractures will be treated with open reduction so as to achieve the near anatomical alignment

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Closed reduction
Description: the non displaced fractures will be treated with closed reduction and percutaneous pinning

Intervention type: OTHER
Group type: OTHER
Intervention: Conservative management
Description: the non displaced fractures will be treated with closed reduction and castor slab
Study: NCT06314958

Intervention type: OTHER
Intervention: CENSURE
Description: A panel of CpG sites, whose methylation level is tested in macro-dissected formalin-fixed and paraffin-embedded (FFPE) samples derived from the primary tumor.

Intervention type: OTHER
Intervention: CENSURE
Description: A panel of CpG sites, whose methylation level is tested in macro-dissected formalin-fixed and paraffin-embedded (FFPE) samples derived from the primary tumor.

Intervention type: OTHER
Intervention: CENSURE
Description: A panel of CpG sites, whose methylation level is tested in macro-dissected formalin-fixed and paraffin-embedded (FFPE) samples derived from the primary tumor.

Intervention type: OTHER
Intervention: CENSURE
Description: A panel of CpG sites, whose methylation level is tested in macro-dissected formalin-fixed and paraffin-embedded (FFPE) samples derived from the primary tumor.
Study: NCT04482530

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit paste matrice
Description: Evaluation of the kinetics of the appearance of nutrients and the metabolic response induced by the consumption of fruit pastes (5 different matrices will be tested: 1 Original recipe, 1 maltodextrine recipe, 1 fructose recipe, 1 isomaltulose recipe and 1 mixed recipe comprising fructose and isomaltulose) in elderly healthy volunteers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit paste matrice
Description: Evaluation of the kinetics of the appearance of nutrients and the metabolic response induced by the consumption of fruit pastes (5 different matrices will be tested: 1 Original recipe, 1 maltodextrine recipe, 1 fructose recipe, 1 isomaltulose recipe and 1 mixed recipe comprising fructose and isomaltulose) in elderly healthy volunteers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit paste matrice
Description: Evaluation of the kinetics of the appearance of nutrients and the metabolic response induced by the consumption of fruit pastes (5 different matrices will be tested: 1 Original recipe, 1 maltodextrine recipe, 1 fructose recipe, 1 isomaltulose recipe and 1 mixed recipe comprising fructose and isomaltulose) in elderly healthy volunteers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit paste matrice
Description: Evaluation of the kinetics of the appearance of nutrients and the metabolic response induced by the consumption of fruit pastes (5 different matrices will be tested: 1 Original recipe, 1 maltodextrine recipe, 1 fructose recipe, 1 isomaltulose recipe and 1 mixed recipe comprising fructose and isomaltulose) in elderly healthy volunteers.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fruit paste matrice
Description: Evaluation of the kinetics of the appearance of nutrients and the metabolic response induced by the consumption of fruit pastes (5 different matrices will be tested: 1 Original recipe, 1 maltodextrine recipe, 1 fructose recipe, 1 isomaltulose recipe and 1 mixed recipe comprising fructose and isomaltulose) in elderly healthy volunteers.
Study: NCT05289271

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaxelis™
Description: Vaxelis™ 0.5 mL sterile suspension in prefilled syringe for intramuscular administration.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Vaxelis™
Description: Vaxelis™ 0.5 mL sterile suspension in prefilled syringe for intramuscular administration.
Study: NCT05333627

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wellbeing Course for Students (Fast Track)
Description: The core Fast-Track lesson includes information on managing their cycle of symptoms, motivation, and an overview of strategies that can be used to manage symptoms of depression and anxiety. After the core lesson, clients can access three additional Do-It-Yourself guides that focus on thought challenging, controlled breathing/activity planning, and behavioural activation/relapse prevention. These materials are able to be accessed out of sequence on a schedule that suits their needs. With optional therapist support, therapists will respond to any messages that clients send once per week. Therapists will not message clients on weeks where the client does not send a message.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wellbeing Course for Students (5 weeks)
Description: The 5-week course consists of four lessons that provide psychoeducation about: symptom identification and the cognitive behavioural model, thought monitoring and challenging, controlled breathing and pleasant activity scheduling, graded exposure, and relapse prevention. With optional therapist support, therapists will respond to any messages that clients send once per week. Therapists will not message clients on weeks where the client does not send a message.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wellbeing Course (8 weeks)
Description: The 8-week course consists of five lessons that provide psychoeducation about: symptom identification and the cognitive behavioural model, thought monitoring and challenging, controlled breathing and pleasant activity scheduling, graded exposure, and relapse prevention. With optional therapist support, therapists will respond to any messages that clients send once per week. Therapists will not message clients on weeks where the client does not send a message.
Study: NCT05980273

Intervention type: BEHAVIORAL
Intervention: Educational sessions
Description: session for oral health education
Study: NCT05712928

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dance/movement therapy (eMove)
Description: Ten weekly 60-minute individual dance/movement therapy telehealth sessions (eMove) delivered by a board-certified dance/movement therapist. eMove treatment protocol integrates movement techniques, creative embodiment, the non-verbal aspects of self-awareness and interpersonal communication in treatment. eMove sessions focus on helping the participant to increase physical activity level, increasing participants' energy levels and motivation to stay active and better cope with everyday activities, improving overall functioning; reducing severity of negative symptoms of schizophrenia; and providing participants with a sense of connection and social support by connecting with a therapist. In addition, sessions are individualized to the participant's presenting needs.
Study: NCT06585787

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Specified dose on specified days
Study: NCT06302504

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nature-based mindfulness program
Description: only one arm is included in this study
Study: NCT06376799

Intervention type: OTHER
Intervention: Self-questionnaire
Description: Provision of a self-questionnaire in digital or paper format for the patient. The patient will be asked to indicate their preferences regarding the primary and secondary objectives of the study.
Study: NCT04798001

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 1, Single Dose, Intranasal Drops
Description: Single intranasal dose on Day 1, by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 1, Single Dose, Intranasal Drops
Description: Single intranasal dose on Day 1, by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 2, Single Dose, Intranasal Drops
Description: Single intranasal dose on Day 1, by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 2, Single Dose, Intranasal Drops
Description: Single intranasal dose on Day 1, by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 3, Single Dose, Intranasal Drops
Description: Single intranasal dose on Day 1, by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 3, Single Dose, Intranasal Drops
Description: Single intranasal dose on Day 1, by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 3, Two Doses, Intranasal Drops
Description: Intranasal dose on Day 1 by intranasal drops. Followed by a second, identical dose on Day 36 by intranasal drops

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational vaccine against SARS-CoV-2 [MV-014-212] Dosage 3, Single Dose, Intranasal Spray
Description: Single intranasal dose on Day 1, by intranasal spray
Study: NCT05833347

Intervention type: DIAGNOSTIC_TEST
Intervention: Distance between Skin-Hyoid Bone(DSHB)
Description: Hyoid bone-skin distance Other Name: DSHB
Study: NCT06591598

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aflibercept (BAY86-5321, Eylea)
Description: 8 mg, intravitreal injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aflibercept (BAY86-5321, Eylea)
Description: 8 mg, intravitreal injection
Study: NCT05833347

Intervention type: DIAGNOSTIC_TEST
Intervention: Distance between Skin-Vocal Cord Anterior Commissura(DSAC)
Description: Vocal cord anterior commissura-skin distance Other Name: DSAC

Intervention type: DIAGNOSTIC_TEST
Intervention: Distance between Skin-Epiglottic(DSE)
Description: Skin-epiglottic distance Other Name: DSE
Study: NCT06046339

Intervention type: OTHER
Intervention: Collection of data from the patient's medical file
Description: Collection of data from the patient's medical file.
Study: NCT06503224

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-BCMA and CD19 CART cells will be injected intravenously on a one-time basis.
Description: A single intravenous infusion of anti-BCMA and CD19 CART cells (dose-escalating infusion of 0.5-3 x10\^6 CART cells/kg）.
Study: NCT05546567

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nicotinamide Riboside
Description: 1200mg x1 Nicotinamide Riboside
Study: NCT05188950

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: depression screening test App
Description: The participants' use of the depression screening test App of 6 modules for 12 weeks, at least once a week, 20 minutes per once.
Study: NCT06591598

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aflibercept (BAY86-5321, Eylea)
Description: 8 mg, intravitreal injection
Study: NCT06679153

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VVN461 Ophthalmic Solution 1.0%
Description: VVN461 Ophthalmic Solution, 1.0%, for up to 28 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VVN461 Ophthalmic Solution 0.5%
Description: VVN461 Ophthalmic Solution, 0.5%, for up to 28 days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Prednisolone acetate
Description: Prednisolone acetate, 1%, for up to 28 days
Study: NCT06678971

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: FIFA 11+
Description: The FIFA 11+ protocol consists of fifteen exercises organized into three segments, with three levels of difficulty. The first segment includes six running exercises, the second focuses on six exercises to enhance lower body strength, balance, and agility, and the third segment involves three running exercises aimed at activating the cardiovascular system.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Basket-Up
Description: The Basket-Up warm-up program is developed by a committee of experts, including the medical staff and the Performance Department of Valencia Basket Club, with detailed information previously published. This protocol is specifically designed to address the physiological, functional, and physical demands of basketball training. Like the FIFA 11+ program, it is structured into three phases with progressively increasing levels of difficulty, lasting a total of 20 minutes.~Phase 1 includes three exercises aimed at improving mobility. Phase 2 features six exercises focused on strength, direction changes, and plyometric activities. Phase 3 consists of six exercises designed to enhance agility and neurocognitive skills.
Study: NCT04959695

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PE Coach
Description: PE Coach is a treatment companion mobile application designed with features to support the tasks of prolonged exposure psychotherapy and the homework between sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prolonged exposure without PE Coach
Description: Standard PE treatment protocol without PE Coach
Study: NCT06617923

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Senaparib
Description: Participants will receive orally 80mg daily Days 1-28 of a 28 day cycle.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Participants will receive orally 20mg daily Days 1-21 of a 28 day cycle.
Study: NCT06085131

Intervention type: DEVICE
Intervention: Argos
Description: Argos Biometer
Study: NCT06675929

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 770371
Description: BI 770371

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for BI 770371
Description: Placebo for BI 770371
Study: NCT06674889

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation-based intervention
Description: Assessment of the subject by a specialty consultation and exercise program development.
Study: NCT06615557

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fasedienol Nasal Spray
Description: Nasal spray delivered 20 minutes before the PSC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Nasal Spray
Description: Nasal spray delivered 20 minutes before the PSC
Study: NCT06615479

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986393
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Daratumumab
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pomalidomide
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Specified dose on specified days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfilzomib
Description: Specified dose on specified days

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carfilzomib
Description: Specified dose on specified days
Study: NCT06251661

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive multi-sensory Rehabilition
Description: Kinetic awareness: Initially, only one joint will be moved at a time. Then the therapist will reposition the joint and ask the participants to report their perception of the joint position. Initially, the participants will distinguish between just two positions. If they reliably answer correctly, increase up to five points and integrate speed and dexterity in functional movements. Participants will be asked to relax and feel the movement during this training. Discrimination exercise: The therapist places a part of the participant's limb, the fingertip, on an external object (a block) and the participant will be asked to actively move his or her limb over the object and try to sense the shape of the object. If the participants differentiate between the two objects, then increase the number of objects (up to five). Functional training: The patient reaches toward many objects functionally (cup, ball, cane) from different angles, holds them, and relocates them again.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: selected traditional physical therapy program.
Description: The selected physical therapy program session will be occupational therapy training for the hand, strengthening exercises for the weak upper limb stretching exercises for short upper limb muscles, balance exercise, and gait training.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: selected traditional physical therapy program.
Description: The selected physical therapy program session will be occupational therapy training for the hand, strengthening exercises for the weak upper limb stretching exercises for short upper limb muscles, balance exercise, and gait training.
Study: NCT05959538

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Building Regulation in Dual Generations (BRIDGE)
Description: The BRIDGE intervention includes 16 weeks of 20-30 minute DBT and parenting skills training videos, delivered asynchronously via an online website requiring a participant login. Video content was drawn from concepts outlined in the DBT Skills Training Manual 2nd Edition (Linehan, 2015). Parenting videos will provide mothers with parenting skills education based on best practices in evidence-based positive parenting interventions (e.g., Parent Management Training, Positive Parenting, Kazdin, 1997; Sanders et al., 2014). The BRIDGE condition also includes weekly synchronous 1-hour virtual group therapy sessions and worksheets to complete weekly (as an opportunity to practice skill use). The clinical team will consist of two Master's or PhD level clinical psychology trainees and a parent peer coach. Mood tracking will be completed using a brief weekly survey, including questions on depression, parenting stress, positive mood, and recent stressful experiences.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dialectical Behavioural Therapy Skill Training
Description: Participants in the DBT arm will participate in 16 weeks of DBT skills training only led by two Master's or PhD level clinical psychology trainees. Participants in the DBT Skills condition will participate in a skills group which follows the DBT Skills Training Manual 2nd Edition (Linehan, 2015) through weekly, synchronous 1.5-hour virtual group therapy sessions. Mindfulness, Emotion Regulation, Distress Tolerance, and Interpersonal Effectiveness skill domains will be covered. Participants will be asked to complete worksheets between sessions to practice using skills, and will be asked to complete a Diary Card to track DBT skills use each week (Linehan, 2015). Mood tracking will be completed using a brief weekly survey including questions on depression, parenting stress, positive mood, and recent stressful experiences.
Study: NCT06672809

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Core Stability Training
Description: Participants in this group undergo core stability training sessions targeting deep stabilizing muscles. The exercises are designed to enhance spinal support and core control by activating the transversus abdominis and other core muscles. Sessions involve the use of a Pilates reformer and other unstable surfaces, fostering proprioceptive engagement and improved muscle coordination. Training is conducted three times per week for eight weeks, with each session lasting 50 minutes.
Study: NCT04646889

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AR882 Single Dose
Description: A single dose of AR882

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AR882 Single Dose
Description: A single dose of AR882
Study: NCT06679985

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Casdozokitug
Description: Solution for infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Casdozokitug
Description: Solution for infusion