TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT06736444

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Behavioral Therapy for Insomnia (BBTI)
Description: Brief Behavioral Therapy for Insomnia (BBTI) focuses primarily on stimulus control and sleep restriction as well as sleep hygiene recommendations delivered over 2 in-person sessions and 2 brief telephone boosters and is designed to be implemented by nonspecialists in primary care or other non-clinical settings. The intervention is manualized, and clients utilize sleep diaries and workbook assignments to consolidate recommendations.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brief Behavioral Therapy for Insomnia (BBTI)
Description: Brief Behavioral Therapy for Insomnia (BBTI) focuses primarily on stimulus control and sleep restriction as well as sleep hygiene recommendations delivered over 2 in-person sessions and 2 brief telephone boosters and is designed to be implemented by nonspecialists in primary care or other non-clinical settings. The intervention is manualized, and clients utilize sleep diaries and workbook assignments to consolidate recommendations.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brief Alcohol Screening and Intervention for College Students (BASICS)
Description: Brief Alcohol Screening and Intervention for College Students (BASICS) is a manualized brief intervention targeting alcohol use and consequences among high risk drinkers and includes both personalized feedback regarding drinking norms, consequences, and motives for drinking, as well as protective behavioral skills for reducing heavy episodic drinking and related consequences. BASICS is delivered in a motivational interviewing (MI) style (Miller \& Rollnick, 2002) to enhance intrinsic motivation to change drinking and implement protective behavioral strategies. BASICS has been adapted to target marijuana use and has been adapted for use with a variety of populations.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Alcohol Screening and Intervention for College Students (BASICS)
Description: Brief Alcohol Screening and Intervention for College Students (BASICS) is a manualized brief intervention targeting alcohol use and consequences among high risk drinkers and includes both personalized feedback regarding drinking norms, consequences, and motives for drinking, as well as protective behavioral skills for reducing heavy episodic drinking and related consequences. BASICS is delivered in a motivational interviewing (MI) style (Miller \& Rollnick, 2002) to enhance intrinsic motivation to change drinking and implement protective behavioral strategies. BASICS has been adapted to target marijuana use and has been adapted for use with a variety of populations.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Attention Control
Description: Attention Control is comprised of 4 weekly 20-minute check-ins with a study therapists regarding the daily monitoring and mood/functioning. Referrals for additional services will be provided as needed.
Study: NCT06735521

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance stress-perfusion
Description: Included patients will be examined at the Karolinska University Hospital in a 1.5T Siemens Sola magnetic resonance camera at rest and during adenosine stress with specific CMR sequences (adenosine stress-perfusion, myocardial velocities, and tissue characterization) for non-invasive determination of macro- and microvascular dysfunction, global myocardial function, pulmonary artery pressure and scarring of the myocardium.~Adenosine or Regadenoson will be used as stress medication which is according to clinical routine. Adenosine will be infused over approximately 5 minutes (110-140 μg / kg/min), Regadenoson (5 ml) will be a 10-second injection (400 μg single dosage). Intravenous gadolinium-based contrast agents will be administered, Gadovist (1 mmol/ml, gadobuterol), 0.15 mmol/kg during stress and rest.
Study: NCT06473974

Intervention type: DRUG
Group type: OTHER
Intervention: Test cosmetic product
Description: Test cosmetic product: Test cosmetic product will be applied to affected hyperpigmented areas twice daily at AM and PM.~Cleanser and sunscreen: A facial cleanser will be used twice daily (morning and evening) by gently rubbing it on face and neck, then rinse and pat dry. Sunscreen of SPF 50, apply evenly on face and neck, 20 minutes before stepping out.
Study: NCT05370612

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dexcom G6 CGM
Description: Dexcom 6 CGM, an FDA approved device. Sensors will be placed on the abdomen per package instruction to collect continuous glucose data.~Experimental Group will wear CGM for the duration of their pregnancy.~Control Group will have CGM data collected for 10 days at enrollment and at 28-32 weeks into their pregnancy.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dexcom G6 CGM
Description: Dexcom 6 CGM, an FDA approved device. Sensors will be placed on the abdomen per package instruction to collect continuous glucose data.~Experimental Group will wear CGM for the duration of their pregnancy.~Control Group will have CGM data collected for 10 days at enrollment and at 28-32 weeks into their pregnancy.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Participant Finger Stick Glucose Monitoring
Description: Standard of care for individual participant
Study: NCT04560660

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: FDA approved anesthetic medication with rapid acting antidepressant effects.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Midazolam
Description: FDA approved sedative medication with dissociative effects.
Study: NCT05102084

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Listening to music with a bluetooth headset to patients receiving CPAP support
Description: Listening to music with a bluetooth headset during the CPAP application to the patients and checking the compatibility on the CPAP device.
Study: NCT05377190

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Continuum HFC-IN
Description: Combination of a mobile application (with remote monitoring) and digital therapeutics

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard of care for the follow-up
Description: No mobile application or digital therapeutics are used

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard of care for the follow-up
Description: No mobile application or digital therapeutics are used

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Continuum HFC-OUT
Description: Combination of a mobile application (without remote monitoring) and digital therapeutics
Study: NCT05983549

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: fluid balance
Description: patients will receive fluids with the aim to achieve a neutral balance
Study: NCT04564963

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cryotherapy
Description: Application of cryotherapy (e.g. ice in resealable zipper storage bags, gel packs, ice packs) over largest closed incision in the post-operative period every 4 hours, at minimum, for up to 72 hours (while participant is awake and admitted to hospital). The cryotherapy should not be placed in direct contact with skin.
Study: NCT05510765

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transportation service
Description: Improved transportation assets applied to all aspects of subjects life
Study: NCT05570942

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Oral Lactobacillus rhamnosus TCELL-1
Description: A kind of probiotics which was isolated from the intestinal mucosa of health Taiwanese people

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Oral Lactobacillus rhamnosus TCELL-1
Description: A kind of probiotics which was isolated from the intestinal mucosa of health Taiwanese people
Study: NCT04824638

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 3 doses of BNT162b2 vaccine
Description: Administration of BNT162 b2 vaccine (30µg in 0.3mL) at D1 D29 and M8, intramuscularly (participants without antecedent of SARS-CoV-2 infection)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2 dose of BNT162b2 vaccine
Description: Administration of BNT162 b2 vaccine (30µg in 0.3mL) at D1 and M8, intramuscularly (participants with antecedent of SARS-CoV-2 infection)
Study: NCT05048953

Intervention type: DIAGNOSTIC_TEST
Intervention: Muscle ultrasound measurements (the index test)
Description: The following parameters will be measured by muscle ultrasound~1. Muscle thickness~2. Muscle echogenicity~3. Muscle fasciculations
Study: NCT06359366

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: perineal massage combined hip joint training
Description: pregnant women take the lithotomy position, disinfect the vulva, and wear sterile gloves. Then thumbs, forefingers, and middle fingers dip massage oil to do a 2 minutes pressurized dilatation massage from inside to outside gently to loosen the fascia. Then rest 30s. All steps need to be repeated 2 to 3 times. When the pregnant women feel a slight sense of acidity and tingling sensation disappears, researchers sterilize the perineal body again. left side pelvic floor receives the same intervention as right. The whole process takes 15-20min, 5 times a week until delivery. Additionally, while using the pelvic floor fascia manipulation, pregnant women are instructed to perform specific movements of internal and external hip rotation, adduction and abduction, upward and downward.
Study: NCT06472154

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental
Description: The experimental group intervened based on the midnight-noon ebb-flow theory, listening to music corresponding to the five organs at different time periods.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: The control group listened to Chinese five elements music pieces from 13:00 to 18:00 p.m., each music piece for within 30 minutes for, 5 days per week, 4 weeks for a cycle, 3 cycles in total.
Study: NCT05317247

Intervention type: DIAGNOSTIC_TEST
Intervention: Cough sounds
Description: The investigators will discover a cough audio signature and then validate it.

Intervention type: DIAGNOSTIC_TEST
Intervention: Cough sounds
Description: The investigators will discover a cough audio signature and then validate it.
Study: NCT05315362

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: solid microneedle skin patch
Description: intradermal vaccination with a skin patch

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: mRNA-1273
Description: administration of mRNA-1273 vaccine

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273
Description: administration of mRNA-1273 vaccine

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: standard needle
Description: intramuscular vaccination with a standard needle
Study: NCT06157957

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Lung cancer screening with low dose CT scan
Description: Low dose CT scan in active smokers or ex-smokers with an age between 50 and 75 years old
Study: NCT05443230

Intervention type: DIAGNOSTIC_TEST
Intervention: gait speed; ct scan; grip strength and chair stand test
Description: The chair stand test was administered, and the time required for the patient to stand five times from a sitting position without using the arms was measured. CT scan was to scan the patient's third lumbar level. For the gait speed test, the time that patients spent walking 8 meters on a flat indoor floor at usual walking speed was measured.Grip strength test:the dominant hand and the nondominant hand were measured twice intermittently (kg), and the average value of 4 values was obtained.

Intervention type: DIAGNOSTIC_TEST
Intervention: gait speed; ct scan; grip strength and chair stand test
Description: The chair stand test was administered, and the time required for the patient to stand five times from a sitting position without using the arms was measured. CT scan was to scan the patient's third lumbar level. For the gait speed test, the time that patients spent walking 8 meters on a flat indoor floor at usual walking speed was measured.Grip strength test:the dominant hand and the nondominant hand were measured twice intermittently (kg), and the average value of 4 values was obtained.
Study: NCT06495528

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pain management with BLISS DTx
Description: Bliss DTx is a Digital Therapeutics (DTx) which uses virtual reality augmented with sound and visual stimuli to reduce pain during Port-A-Cath setting

Intervention type: OTHER
Group type: OTHER
Intervention: Pain Management with site standard of care sedation protocol
Description: Sedation (morphine and/or hypnotics and/or anxiolytics and/or conversational hypnosis) reduces pain during Port-A-Cath setting
Study: NCT05895604

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-Family Partnership
Description: Nurse-Family Partnership is a prenatal and infancy home visiting program providing regular visits to first-time mothers until the child is two years old
Study: NCT05030454

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ETHOS
Description: Ring-gantry CT-guided radiotherapy unit, pairing a linear accelerator within a ring-gantry imaging unit.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: CT-guided stereotactic adaptive radiotherapy
Description: All participants will be initially planned to at least 35 Gy in 5 fractions, subject to hard constraints based on the treatment site.
Study: NCT06401564

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Therapy
Description: Each participant will receive one or two 20 minute VR sessions during their admission. Participants are able to pause or discontinue at any time. During each VR session, participants will use the REAL Immersive VR system and be equipped with a VR headset and 6 sensors attached to the torso, waist, and upper extremities. Patient will then undergo various virtual challenges guided by the physical or occupational therapist facilitating movements of the upper extremity, core, head, and neck.
Study: NCT05623397

Intervention type: OTHER
Intervention: Acquisition of a digitized ECG by four modalities within 20 minutes
Description: Patients will have three visits during the cycle for a given dose (600mg/day, 400mg/day or 200mg/day): Baseline , Day 14, Day 28~At each visit, the patient will have the acquisition of a digitized ECG by four modalities within 20 minutes (A 10 second triplicate ECG with WELCH-ALYN ELI-280® with the three 10 sec ECGs collected at approximatively 2-minute intervals, 3 min holter acquisition with a CGM HI-patch ®, a 3 minutes acquisition with AliveCore 6L® device and 10 seconds triplicate acquisition with QT-medical ® device collected at approximatively 2-minute intervals ).~Concomitantly with the ECG acquisition, patients will have blood sampling for measurements of variables clinically important for assessment of QTc including potassium, fasting blood glucose, calcemia, magnesium, estradiol, progesterone, FSH, LH, D4-androstenedione, total and free testosterone, SHBG and TSH. Blood concentration of ribociclib will be also assessed.
Study: NCT06070844

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: yoga nidra
Description: Yoga Nidra is a guided meditation technique that involves listening to audio readings. Yoga nidra application will be started at the 6th postoperative hour and will be applied one time. Yoga nidra is expressed as yoga sleep or deep relaxation. In this practice, it will be ensured that the mother will mentally visualise all parts of her body with the commands to be given during controlled breathing and emotionally feel the body parts. The Yoga Nidra application will last 30 minutes.
Study: NCT06417320

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ACEI, SGLT-2i
Description: Group 1 (ACEI group) will receive a single dose of oral ACE inhibitors tablets per day (0.2-0.6mg) /kg/ day)~❖ Group 2 (combined ACEI and SGLT-2inhibitrs group) patients on a single dose of oral ACE inhibitors tablets per day (0.2-0.6mg /kg/ day) presenting with persistent nephrotic range proteinuria will add a single dose of oral SGLT-2 inhibitors tablets 5mg per day (weight≤30kg) or 10mg per day (weight \>30kg)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ACEI, SGLT-2i
Description: Group 1 (ACEI group) will receive a single dose of oral ACE inhibitors tablets per day (0.2-0.6mg) /kg/ day)~❖ Group 2 (combined ACEI and SGLT-2inhibitrs group) patients on a single dose of oral ACE inhibitors tablets per day (0.2-0.6mg /kg/ day) presenting with persistent nephrotic range proteinuria will add a single dose of oral SGLT-2 inhibitors tablets 5mg per day (weight≤30kg) or 10mg per day (weight \>30kg)
Study: NCT06171620

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality headset
Description: Distraction therapy using a virtual reality headset. Participants will access a digitally created environment such as a forest or sub sea exploration with relaxing auditory cues.

Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care
Description: Elective procedure performed as planned according to current standard of care in the hospital.
Study: NCT05378841

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Denervation
Description: This is an outpatient procedure performed under local anesthesia (depending on the anesthesiologist's decision), which lasts about 30 minutes.
Study: NCT01161602

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pumosetrag

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pumosetrag

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pumosetrag
Study: NCT05526742

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-510 capsule (reference)
Description: Single-dose of CKD-510 will be administered as oral capsule in a fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-510 capsule (reference)
Description: Single-dose of CKD-510 will be administered as oral capsule in a fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-510 tablet (test)
Description: Single-dose of CKD-510 will be administered as oral tablet in a fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-510 tablet (test)
Description: Single-dose of CKD-510 will be administered as oral tablet in a fasted state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-510 tablet (test)
Description: Single-dose of CKD-510 will be administered as oral tablet in a fed state.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-510 tablet (test)
Description: Single-dose of CKD-510 will be administered as oral tablet in a fed state.
Study: NCT05078619

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: No PCI
Description: Omission of PCI of significant coronary artery disease prior to TAVI
Study: NCT06438848

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical therapy program
Description: group will be prescribed a usual physical therapy program three times a week for four weeks, which will be conducted in the clinic. The program consists of eight sessions comprising warm-up and cool-down, stretching activities, and strengthening exercises, and manual therapy. The program will start with 10-minute warm-up and 10-minute cool-down periods of physical therapy sessions

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical therapy program with lymphedema drainage
Description: physical therapy program three times a week for four weeks, which will be conducted in the clinic. The program consists of eight sessions comprising warm-up and cool-down, stretching activities, and strengthening exercises,And manual lymphatic drainage prescribed 20 minutes of MLD daily. The program will be prescribed five times a week, for four weeks
Study: NCT06489639

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DOCT-SAD
Description: Developmentally Oriented Cognitive Therapy for Social Anxiety Disorder is a 10-session, combined individual/group clinical intervention for treating social anxiety in adolescents. It consists of four individual and six group sessions during ten weeks. DOCT-SAD groups are formed for 4-6 adolescnts. One parent or both parents attend two of the individual sessions.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SC
Description: Standard Counseling (SC) is a intervention consisting of counseling sessions delivered by a school health and welfare (SHWS) professional (i.e., school nurse, school social worker, or school psychologist) to support a student with social anxiety. The defined length of intervention is ten weeks, and number of sessions will be according to what is routinely agreed between the professional and the adolescent. In SC, routine professional working methods and procedures available to the SHWS professional delivering the intervention are used.
Study: NCT06489756

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Echocardiography will be performed according to clinical standards

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Echocardiography
Description: Echocardiography will be performed according to clinical standards
Study: NCT05316532

Intervention type: DEVICE
Intervention: Prismalung + treatment
Description: Low-flow extracorporeal CO2 removal with or without concurrent continuous renal replacement therapy

Intervention type: DEVICE
Intervention: Prismalung + treatment
Description: Low-flow extracorporeal CO2 removal with or without concurrent continuous renal replacement therapy
Study: NCT05030103

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Reading glasses, +2.0 diopters
Description: The participants in the glasses-group are asked to wear the reading glasses during near-work.