TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04586309

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Transcendental meditation
Description: Instruction in the TM technique is taught over five sessions.~1. Introductory session-Review of previous scientific research on the TM program and a vision of possible benefits; Preparation- discussion of the mechanics and origin of the TM technique After the introductory session, a Personal Interview is conducted telephonically-with a teacher of the TM program.~2. Personal Instruction-individual one-on-one instruction in the TM technique. The student learns the mechanics of the TM technique. At the conclusion of this class the student is able to meditate properly.~3. First Day of Verification of Correct Practice and Further Instruction.~4. Second Day of Verification of Correct Practice-understanding the mechanics of the TM technique from personal experiences.~5. Third Day of Verification of Correct Practice-understanding the mechanics of the development of higher human potential and wellness.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transcendental meditation
Description: Instruction in the TM technique is taught over five sessions.~1. Introductory session-Review of previous scientific research on the TM program and a vision of possible benefits; Preparation- discussion of the mechanics and origin of the TM technique After the introductory session, a Personal Interview is conducted telephonically-with a teacher of the TM program.~2. Personal Instruction-individual one-on-one instruction in the TM technique. The student learns the mechanics of the TM technique. At the conclusion of this class the student is able to meditate properly.~3. First Day of Verification of Correct Practice and Further Instruction.~4. Second Day of Verification of Correct Practice-understanding the mechanics of the TM technique from personal experiences.~5. Third Day of Verification of Correct Practice-understanding the mechanics of the development of higher human potential and wellness.
Study: NCT04550611

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mini-pool Intravenous Immunoglobulin (MP-IVIG)
Description: The process of MP-IVIG preparation will involve the use of caprylic acid for purification and virus inactivation of Igs from mini-pools of 20 plasma donations collected in our CBTS in AUH. The equipment used for the process comprised disposable blood bags, hemodialyzers, and purification and microbial filters.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: plasma exchange
Description: plasma exchange (plasmapheresis ) in a regimen of removing of 1.3 plasma volumes in each cycle for total of five cycle for five consecutive days within four weeks of onset of symptoms.
Study: NCT05450458

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KNEE JOINT INFILTRATION WITH HYALURONIC ACID WITH SORBITOL SYNOLIS VA
Description: KNEE INFILTRATION WITH HYALURONIC ACID WITH SORBITOL IN SPORTSMEN
Study: NCT05906771

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Nutraceutical placebo
Description: The participating subjects will have to follow the intake of the nutraceutical for 3 months, as well as attend the stipulated visits. Participants will be given a register to control their daily intake of the nutraceutical. They should not change their daily habits.~Nutraceutical placebo contains microcystalline cellulose (185mg) and maltodextrin (185mg).
Study: NCT05912621

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Tirzepatide dose is titrated up by 2.5 mg every four weeks as per below, starting with 2.5 mg weekly and maxing out at 15 mg.
Study: NCT05447507

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remimazolam
Description: 0.075 mg/kg Remimazolam bolus infusion for 1 min, then 0.5\~1.0 mg/kg/h continuous infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: 1 mcg/kg Dexmedetomidine infusion for 10 min, then 0.2\~0.7 mcg/kg/h continuous infusion
Study: NCT06199713

Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
Description: research scan 3-4 weeks after start of immunotherapy
Study: NCT06064487

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: renal cell arrest and damage biomarkers assessment
Description: measurement of TIMP2 and IGFBP7, KIM-1
Study: NCT05448846

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Recovery After Surgery
Description: ERAS protocol includes preoperative counselling, optimization of nutrition, standardized analgesic and anesthetic regimens and early mobilization.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Enhanced Recovery After Surgery
Description: ERAS protocol includes preoperative counselling, optimization of nutrition, standardized analgesic and anesthetic regimens and early mobilization.
Study: NCT06413732

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physiotherapy
Description: Conventional physiotherapy was applied for approximately 1 hour, 5 days a week.

Intervention type: OTHER
Group type: OTHER
Intervention: Conventional physiotherapy
Description: Conventional physiotherapy was applied for approximately 1 hour, 5 days a week.
Study: NCT05365841

Intervention type: DRUG
Intervention: Mepolizumab 100 MG
Description: Patients with SEA eligible to receive anti-IL5 treatment, which is a biologic treatment for SEA

Intervention type: DRUG
Intervention: Mepolizumab 100 MG
Description: Patients with SEA eligible to receive anti-IL5 treatment, which is a biologic treatment for SEA
Study: NCT04665206

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VT3989
Description: 25, 50, 100,150 or 200 mg capsules for oral administration.
Study: NCT05909644

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omaveloxolone
Description: Omaveloxolone Capsules, 150 mg, administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Efavirenz
Description: Efavirenz Tablet, 600 mg, administered orally once daily
Study: NCT05505461

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: neoadjuvant Radiation plus SOX and PD-1 antibody
Description: Patients will be given the perioperative treatment as below once recruited:~First, neoradiation (5w) will be given: intensity modulated radiotherapy was given for tumors and high-risk lymphatic drainage areas. PD-1 antibody will be started concurrent the radiation for 2 cycles.~The neochemotherapy (SOX) and PD-1 antibody will be given for 2 cycles after 1 week since radiation completed ; Patients will rest 2 weeks after the last cycle of neochemotherapy, and evaluation will be performed during this time. And D2 surgery will be performed if resectable.~SOX and PD-1 antibody will be given q3w. Adjuvant chemotherapy: We advise starting 4 cycles of SOX regimen in 3-8w after surgery.
Study: NCT06583733

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: KOKU Bladder
Description: In this intervention the participants will receive treatment with the KOKU app ( based digital health program with behavior change techniques to improve bladder health ) for 12 weeks.~After the intervention we will collect the results with a mixed (qualitative and quantitative) approach. Qualitative information will be recorded and analysed through thematic analysis, and quantitative data will be collected with tests and questionnaires.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: recommendations
Description: In this intervention the participants will receive recommendations for self- managing urinary symptoms, which they must follow for 12 weeks.~After the intervention we will collect the results with a mixed (qualitative and quantitative) approach. Qualitative information will be recorded and analysed through thematic analysis, and quantitative data will be collected with tests and questionnaires.
Study: NCT06070662

Intervention type: DIAGNOSTIC_TEST
Intervention: Coronary microvascular disease testing during coronary angiography
Description: During invasive coronary angiography, in addition to coronary angiography performed as per routine clinical care, participants will have angiographic testing for coronary microvascular disease using routine clinical procedures. This will consist of fractional flow reserve (FFR), coronary flow reserve, index of microvascular resistance and vasospasm provocation testing with acetylcholine (Ach).

Intervention type: DIAGNOSTIC_TEST
Intervention: Coronary microvascular disease testing during coronary angiography
Description: During invasive coronary angiography, in addition to coronary angiography performed as per routine clinical care, participants will have angiographic testing for coronary microvascular disease using routine clinical procedures. This will consist of fractional flow reserve (FFR), coronary flow reserve, index of microvascular resistance and vasospasm provocation testing with acetylcholine (Ach).
Study: NCT06070662

Intervention type: DIAGNOSTIC_TEST
Intervention: Coronary microvascular disease testing during coronary angiography
Description: During invasive coronary angiography, in addition to coronary angiography performed as per routine clinical care, participants will have angiographic testing for coronary microvascular disease using routine clinical procedures. This will consist of fractional flow reserve (FFR), coronary flow reserve, index of microvascular resistance and vasospasm provocation testing with acetylcholine (Ach).

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance scan including exercise
Description: Participants will undergo a cardiac magnetic resonance scan compromising 1) T1 mapping, 2) oxygenation-sensitive MRI and 3) perfusion imaging. All will be obtained at rest and during exercise using a step ergometer.

Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance scan including exercise
Description: Participants will undergo a cardiac magnetic resonance scan compromising 1) T1 mapping, 2) oxygenation-sensitive MRI and 3) perfusion imaging. All will be obtained at rest and during exercise using a step ergometer.

Intervention type: DIAGNOSTIC_TEST
Intervention: Additional analysis of already acquired CT scan
Description: Previously acquired CTCA images from the main research study will be transferred to Heartflow for computation of coronary blood volume.

Intervention type: DIAGNOSTIC_TEST
Intervention: Additional analysis of already acquired CT scan
Description: Previously acquired CTCA images from the main research study will be transferred to Heartflow for computation of coronary blood volume.
Study: NCT06509373

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Advance Care Planning Tool - ACPVoice
Description: Eligible patients will be sent a secure MyChart message with a motivational message asking them to complete the advance care planning tool (ACPVoice) with their care partner/surrogate decision-maker or loved one before their upcoming primary care visit. The ACPVoice tool will be attached electronically to the mychart message. A reminder message will be sent to an non-responders with a different motivational message.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care for Advance Care Planning
Description: Patients will have access to the standardized advance care planning questionnaires readily available already within their mychart account which is part of standard of care.
Study: NCT06632626

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Task oriented training exercises
Description: Task oriented training is a type of exercises in form of tasks using papers, pens, scissors, clips, coins, screws and clay

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physical therapy
Description: Traditional physical therapy inform of mobilization, strengthening exercises of hand and streching exercises.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physical therapy
Description: Traditional physical therapy inform of mobilization, strengthening exercises of hand and streching exercises.
Study: NCT06135753

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: psychosomatic intervention based on cognitive restructuring.
Description: Participants will receive information on psychosomatic phenomena and over-listening of somatic manifestations (Session 1), interpretation and possible catastrophization of somatic manifestations even when they might be well-known health problems or potential physiological or para-physiological manifestations (Session 2), pain-proneness (Session 3) and mental pain and psychological distress in somatizers (Session 4). The second part of each session will be devoted to group cognitive restructuring, thus participants will be stimulated in verifying how the phenomena illustrated are in their lives and how they can be differently conceptualized in order to be less intrusive and less able to reduce their own functioning.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Control condition
Description: The control condition will include 4 sessions that will inform participants about well-being and lifestyles which can influence it. They will be articulated as follows. Session 1: illustrating the concept of lifestyle and well-being. Session 2 and session 3: illustrating healthy eating and steps to healthy eating. Session 4: illustrating physical exercise and how it promotes health.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental and control condition: Museum therapy
Description: Session 5-6-7: preselected painting works from the Uffizi Galleries (Florence) will be presented to the participants in order to trigger reflections and emotional responses on specific pain related topics. Session 8: visit the Galleria di Arte Moderna at Palazzo Pitti, in person. Each session will be aimed at facilitating emotional expressions and partecipants' behavioral activation and identifying thoughts associated with those emotions and, if appropriate, remodulating them in a functional way (cognitive restructuring).~Session 9: share the experience of the previous meetings and to recap strategies and skills which could be implemented in FM participants' daily life to cope with their illness.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Experimental and control condition: Museum therapy
Description: Session 5-6-7: preselected painting works from the Uffizi Galleries (Florence) will be presented to the participants in order to trigger reflections and emotional responses on specific pain related topics. Session 8: visit the Galleria di Arte Moderna at Palazzo Pitti, in person. Each session will be aimed at facilitating emotional expressions and partecipants' behavioral activation and identifying thoughts associated with those emotions and, if appropriate, remodulating them in a functional way (cognitive restructuring).~Session 9: share the experience of the previous meetings and to recap strategies and skills which could be implemented in FM participants' daily life to cope with their illness.
Study: NCT06129838

Intervention type: DRUG
Intervention: [11C]-CS1P1
Description: Participants will receive a single intravenous bolus injection of 12.0 - 17.0 milliCurie (mCi) of the investigational radiotracer \[11C\]-CS1P1. Participants will then undergo a brain \[11C\]-CS1P1 PET scan

Intervention type: DRUG
Intervention: [11C]-CS1P1
Description: Participants will receive a single intravenous bolus injection of 12.0 - 17.0 milliCurie (mCi) of the investigational radiotracer \[11C\]-CS1P1. Participants will then undergo a brain \[11C\]-CS1P1 PET scan
Study: NCT05448846

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based multicomponent exercise program (EXE)
Description: Home-based multicomponent exercise program:~A) Strength and balance (20 to 40 minutes, 2 days/week):~* Chair sit to stand exercise \| 1 to 3 sets completing repetitions until rating 5 to 8 in the Rated of Perceived Exertion, 0-10 scale (RPE).~* Seated curl to press exercise \| 1 to 3 sets completing repetitions until rating 5 to 8 RPE.~* Monopodal balance \| 1 to 3 sets with progressive time targets up to 60-second for each leg.~B) Gait (at least 30 minutes at an intensity that allows for comfortable conversation, 2 days/week on separate days from strength and balance exercise)~C) Inspiratory Muscle Training: 30 inspirations at 40% of maximal inspiratory pressure through a Power Breathe device, 2 times per day)
Study: NCT05078073

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyperbaric oxygen therapy
Description: Patients with aGVHD treated with HBOT every two days
Study: NCT04496479

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LYG-LIV0001
Description: Allogenic hepatocytes suspended in a buffered cell preservation solution with increasing number of lymph nodes being transplanted for the dose escalation. Subjects will also receive immune suppression, including tacrolimus capsules to follow the dose prescribed by the investigator as well as a short course of prednisone.
Study: NCT04810299

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aromatherapy
Description: Aromatherapy; It is one of the complementary therapy methods defined as the therapeutic use of essential oils obtained from parts of plants such as root, seed, leaf, flower, shell with appropriate methods.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Classical foot massage
Description: Classical foot massage; It is defined as a massage technique based on the principle of systematic relaxation
Study: NCT06134713

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cryotherapy with sterile saline at 2.5ºC
Description: In the cryotherapy (experimental group), final irrigation will be performed with 5 ml of 0.9% physiological sterile saline kept refrigerated at 2.5ºC and will be delivered for 1 or 4 minutes with a side vented needle inserted at working length for each canal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cryotherapy with sterile saline at 2.5ºC
Description: In the cryotherapy (experimental group), final irrigation will be performed with 5 ml of 0.9% physiological sterile saline kept refrigerated at 2.5ºC and will be delivered for 1 or 4 minutes with a side vented needle inserted at working length for each canal.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: control with sterile saline at room temperature
Description: In the control group, final irrigation will be performed with 5 ml of 0.9% physiological sterile saline kept at room temperature and will be delivered for 1 or 4 minutes with a side vented needle inserted at working length for each canal.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: control with sterile saline at room temperature
Description: In the control group, final irrigation will be performed with 5 ml of 0.9% physiological sterile saline kept at room temperature and will be delivered for 1 or 4 minutes with a side vented needle inserted at working length for each canal.
Study: NCT06159829

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: experimental
Description: intervention group used VR with a natural landscape and relaxing musical accompaniment during the upper endoscopy procedure.
Study: NCT05717959

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Oropharyngeal Exercises
Description: Oropharyngeal Exercises

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oropharyngeal Exercises
Description: Oropharyngeal Exercises
Study: NCT06069011

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interdisciplinary management
Description: assessment and treatment in an interdisciplinary model

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: usual care
Description: assessment and treatment in usual care model
Study: NCT05465642

Intervention type: OTHER
Intervention: Collect stool and blood samples from patients
Description: Collect stool and blood samples from patients

Intervention type: OTHER
Intervention: Collect stool and blood samples from patients
Description: Collect stool and blood samples from patients
Study: NCT04718194

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ESTEEM iCBT
Description: The online CBT treatment consists of 10 weekly modules that participants will complete over the course of 10 weeks.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Self-monitoring control
Description: Participants will be asked to indicate their past 7-day mood; stress experiences; and mental and behavioral health on an online survey experience once per week for 10 weeks
Study: NCT06389214

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reproxalap Ophthalmic Solution (0.25%)
Description: Reproxalap Ophthalmic Solution (0.25%) administered six times over two consecutive days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Ophthalmic Solution
Description: Vehicle Ophthalmic Solution administered six times over two consecutive days
Study: NCT04803279

Intervention type: DEVICE
Intervention: Collection of Pure tone thresholds from audiogram measured prior to fitting of Ponto 3 SuperPower
Description: Unmasked and if available masked BC thresholds from audiogram obtained prior to Ponto 3 SuperPower were fitted.

Intervention type: DEVICE
Intervention: Collection of BC In-situ thresholds from BC In-situ audiogram measured during fitting of Ponto 3 SuperPower
Description: BC In-situ thresholds will be collected from the BC In-situ audiogram obtained when Ponto 3 SuperPower were fitted

Intervention type: DEVICE
Intervention: Collection of Aided sound field thresholds measured with the Ponto 3 SuperPower
Description: Sound field thresholds for frequencies 500Hz, 1kHz, 2 kHz, 3kHz and 4kHz will be collected from sound field audiogram obtained as follow-up after Ponto 3 SuperPower fitting, typically this is collected 3 months post fitting, alternatively from the fitting visit. Thresholds will be obtained aided, and when available unaided

Intervention type: DEVICE
Intervention: Collection of speech intelligibility scores
Description: Speech intelligibility is measured in a sound treated room using sentence tests. The sentence tests used at Norwich and Norfolk hospital is the BKB (Bamford-Kowal-Bench) and/or the The AB\[s\] Isophonemic Monosyllabic Word test (7).~The sentence tests are measured in quiet and/or with background speech-weighted noise.

Intervention type: DEVICE
Intervention: Skin reaction
Description: Classification of skin reactions around skin penetrating implants will be made using the Holgers score. The Holgers classification is a scale from 0 to 4 that is used to grade skin reactions

Intervention type: DEVICE
Intervention: Collection of Glasgow Benefit Inventory
Description: The Glasgow Benefit Inventory (GBI) contains 18 health status questions, which ask specific questions about how the health problem, in this study hearing loss, has affected their quality of life at the time the GBI is completed. In this study GBI has been collected on patients before intervention and 3 months after fitting of Ponto 3 SuperPower on abutment.

Intervention type: DEVICE
Intervention: Collection of power-on usage time with Ponto 3 SuperPower
Description: Average power-on usage hours from Ponto 3 SuperPower will be collected.