TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04923685

Intervention type: OTHER
Intervention: Trier Social Stress Test
Description: The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.

Intervention type: OTHER
Intervention: Trier Social Stress Test
Description: The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.

Intervention type: OTHER
Intervention: Trier Social Stress Test
Description: The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.

Intervention type: OTHER
Intervention: Trier Social Stress Test
Description: The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.

Intervention type: OTHER
Intervention: Trier Social Stress Test
Description: The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.

Intervention type: OTHER
Intervention: Trier Social Stress Test
Description: The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.
Study: NCT04621279

Intervention type: PROCEDURE
Intervention: Normothermia
Description: Usual care for first 72 hours for neonates with mild encephalopathy maintaining core temperature (36.5°C ± 1 C).

Intervention type: PROCEDURE
Intervention: Whole body therapeutic hypothermia
Description: Whole-body therapeutic hypothermia (33.5°C ± 0.5°C) for 72 hours began by 6 hours of age for neonates with mild encephalopathy per site standard of care practice.
Study: NCT06420349

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Heat Shock Factor 1 Pathway Inhibitor NXP800
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-Guided Biopsy
Description: Undergo ultrasound-guided liver biopsy
Study: NCT05034289

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PINPOINT Digital Educational Tool
Description: The intervention prototype called the PINPOINT Digital Educational Tool will be comprised of four main sections that include information about: 1) precision oncology; 2) clinical trials; 3) Learn More screens; and 4) discussion points and questions for the treating clinician. The intervention prototype will also include a search function, short videos of patient testimonials, patient-provider interaction about immunotherapy and clinical trials, as well as a list of questions/concerns that the patient could print (or save electronically) and take with them to their provider visit. An optional chatbot will be available in the corner of the screen. Users can ask the chatbot questions about any of the material on the website or request additional information. The chatbot will also be able to help patients search for molecularly targeted and immunotherapy clinical trials and offer additional resources (such as websites and online support groups).
Study: NCT05710328

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Receive standard of care chemotherapy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo PET/CT

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fludeoxyglucose F-18
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Procedure
Description: Undergo standard of care surgery
Study: NCT05710627

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TENEX
Description: Use of TENEX device for sectioning of the gluteus medius and ITB tendons.
Study: NCT06183944

Intervention type: OTHER
Intervention: Hierarchical clustering methods
Description: Hierarchical clustering methods will be used to form homogeneous groups of patients based on their data at diagnosis: presence or absence of symptoms, clinical and biological data, and presence or absence of favouring factors. Patient evolution at 6 months can fall into categories: stable, aggravation or progress, which are determined by events such as recurrence, hemorrhage, functional sequelae or death.
Study: NCT06308718

Intervention type: BIOLOGICAL
Intervention: FBX-101
Description: A replication-deficient adeno-associated virus gene transfer vector expressing the human galactocerebrosidase (hGALC) cDNA will be delivered one-time through a venous catheter inserted into a peripheral limb vein.
Study: NCT05290064

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, high energy density
Description: Ultra-processed diet that is high in non-beverage energy density and low in hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, high energy density
Description: Ultra-processed diet that is high in non-beverage energy density and low in hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, high energy density
Description: Ultra-processed diet that is high in non-beverage energy density and low in hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, high energy density
Description: Ultra-processed diet that is high in non-beverage energy density and low in hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both low
Description: Ultra-processed diet that is low in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both low
Description: Ultra-processed diet that is low in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both low
Description: Ultra-processed diet that is low in both non-beverage energy density and hyperpalatable foods
Study: NCT06101342

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenacapavir Injection
Description: Administered subcutaneously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenacapavir Injection
Description: Administered subcutaneously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenacapavir Tablet
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenacapavir Tablet
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
Description: Administered orally

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
Description: Administered orally
Study: NCT04585269

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bright IDEAS-YA
Description: Bright IDEAS-YA is a manualized problem-solving skills training intervention conducted by a trainer who teaches the participant the Bright IDEAS stepwise approach to problem-solving and guides the participant through solving their own problems using the Bright IDEAS approach.
Study: NCT06157177

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metaxalone 640 mg Oral Tablet
Description: Metaxalone 640 mg used for the treatment of discomforts associated with acute, musculoskeletal pain.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Metaxalone 640 mg Oral Tablet
Description: Metaxalone 640 mg used for the treatment of discomforts associated with acute, musculoskeletal pain.
Study: NCT06039930

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele PROTECT
Description: Tele-PROTECT is a behavioral intervention delivered virtually over nine 45-minute sessions for depressed elder abuse (EA) victims. It is designed to work in synergy with EA resolution services that provide safety planning, support services, and links to legal services.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Depression Education
Description: DepEd is designed as an intervention delivered virtually over nine 45-minute sessions with active therapeutic ingredients (education, support, empathy). It is designed to be what a good clinician providing education would do with an individual with depression.
Study: NCT05638269

Intervention type: OTHER
Intervention: no intervention
Description: Observational studies, no intervention

Intervention type: OTHER
Intervention: no intervention
Description: Observational studies, no intervention
Study: NCT04445883

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feeding Assistance
Description: Patients will be receiving assistance during mealtimes. This includes assistance by opening packages, listing/explaining the food products on the tray, providing encouragement and companionship during mealtimes and directly feed patients.
Study: NCT06172803

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Restoring Energy with Sub-symptom Threshold Aerobic Rehabilitation Exercise
Description: 8 week exercise program. 20 minutes of home aerobic exercise most days, phone- based motivational exercise coaching and supervised exercise with our team exercise physiologist.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Light Stretching/Breathing Exercises
Description: The control group will receive 8-week, attention-matched, stretching and breathing exercises, supervised by a rehabilitation clinician (via 20-minute weekly video visits). Exercises performed 5 days a week will not increase HR significantly. Participants will record and track their HR with Apple watch and app; like RESToRE, fidelity of treatment will be objectively measured using HR data.
Study: NCT06523218

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MindMD Supplement
Description: Participants will take two capsules of the MindMD supplement once daily with their morning meal for a duration of 3 months. The supplement is designed to improve and maintain cognitive function and memory.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will take two capsules of the placebo once daily with their morning meal for a duration of 3 months. The placebo is designed to be indistinguishable in appearance and administration from the MindMD supplement to ensure blinding.
Study: NCT06481878

Intervention type: DIAGNOSTIC_TEST
Intervention: faecal analysis
Description: Collection of medical data and stool sampling

Intervention type: DIAGNOSTIC_TEST
Intervention: faecal analysis
Description: Collection of medical data and stool sampling

Intervention type: DIAGNOSTIC_TEST
Intervention: faecal analysis
Description: Collection of medical data and stool sampling

Intervention type: DIAGNOSTIC_TEST
Intervention: faecal analysis
Description: Collection of medical data and stool sampling
Study: NCT06648915

Intervention type: DIAGNOSTIC_TEST
Intervention: Lipoprotein(a)
Description: Measurement of Lp(a) was performed at the time of entry to the registry. Lp(a) level was measured using immunenephelometric assay
Study: NCT05290064

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both low
Description: Ultra-processed diet that is low in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both high
Description: Ultra-processed diet that is high in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both high
Description: Ultra-processed diet that is high in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both high
Description: Ultra-processed diet that is high in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultra-processed food, both high
Description: Ultra-processed diet that is high in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unprocessed food diet
Description: Unprocessed diet that is low in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unprocessed food diet
Description: Unprocessed diet that is low in both non-beverage energy density and hyperpalatable foods
Study: NCT06481878

Intervention type: DIAGNOSTIC_TEST
Intervention: faecal analysis
Description: Collection of medical data and stool sampling
Study: NCT06107816

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: Visit with a primary care provider and referral for diabetes self-management education and support (DSME/S) sessions

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: F&V Rx alone
Description: Usual Care plus four F\&V prescriptions that are independent of DSME/S attendance

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: F&V Rx plus DSME/S
Description: Usual Care plus four F\&V prescriptions that are dependent on DSME/S attendance
Study: NCT05724966

Intervention type: DEVICE
Intervention: mHealth app
Description: We wish to examine the perspectives of patients with multiple myeloma and healthcare professionals of this new method for reporting side effects, and to assess organizational aspects. Usual procedure to assess side effect prior to cancer treatment with Bortezomib is a telephone call the day before.
Study: NCT05670821

Intervention type: DRUG
Intervention: Spesolimab
Description: Spesolimab
Study: NCT05456932

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravenous iron
Description: Included participants will receive intravenous iron therapy, the dosage will be based on national pharmaceutical formulary.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ferric maltol
Description: Included participants will receive oral iron therapy with ferric maltol (twice a day 30mg for 12 weeks)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ferrous fumarate
Description: Included participants will receive oral iron therapy with ferrous fumarate (twice a day 100mg for 12 weeks)
Study: NCT05717127

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time restricted feeding
Description: Restricted feeding with 20 hours of fasting and a 4 hour window of feeding (between 4 and 8 PM or between 5 to 9 PM).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard lifestyle
Description: Standard lifestyle recommendations
Study: NCT05290064

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unprocessed food diet
Description: Unprocessed diet that is low in both non-beverage energy density and hyperpalatable foods

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unprocessed food diet
Description: Unprocessed diet that is low in both non-beverage energy density and hyperpalatable foods
Study: NCT04922320

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Priorities Care
Description: A facilitator will schedule a PPC facilitation encounter 2-3 weeks before an upcoming PCP visit. The facilitator conducts a structured assessment using a written conversation guide that begins with general questions establishing what is most important to Veterans about their health and moves toward establishing specific goals (actionable outcomes), and what patients are willing/not willing to do to achieve these goals (care preferences). The result is a structured patient priorities report delivered to PCPs designed to facilitate changes in the patient's care plan to align it with his/her priorities. In the subsequent visit, the PCP will use one or more of the established PPC decisional strategies to align care with patients' priorities. Education for PCPs about the facilitation process, the patient priorities report, and the decisional strategies occurs prior to the PCP seeing any intervention patients. The PCP will document changes in care made to achieve the identified priorities.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: PCPs will not be alerted when an encounter involves a UC group participant. UC participant visits will appear the same as all other unenrolled patient encounters. PCPs will be trained to address the needs of UC participants based on their typical approach without the use of a facilitator or explicit process for identifying patient priorities. UC participants will not receive any additional preparation
Study: NCT06150599

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sacral neuromodulation
Description: Interstim X, which includes an implantable pulse generator and lead, will be implanted surgically in a single-stage procedure.
Study: NCT05098197

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tumor Infiltrating Lymphocyte
Description: Adoptive transfer of 1x10\^9-5x10\^10 autologous TILs to patients i.v. in 30-120 minutes.
Study: NCT05664594

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Computerized Cognitive Training
Description: Participants will complete computerized cognitive training developed by Posit Science Corporation. For a description of the training paradigms please review arm descriptions.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Computerized Cognitive Training
Description: Participants will complete computerized cognitive training developed by Posit Science Corporation. For a description of the training paradigms please review arm descriptions.
Study: NCT05767658

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Safe Sleep
Description: Participants will be part of a private Facebook group from approximately 32 weeks gestation to 6 months postpartum. The Facebook group will provide a) evidence-based education through videos and other multi-media supporting best practices for infant safe sleep and b) an online community and social network of other pregnant WIC clients and new parents.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Safe Sleep
Description: Participants will be part of a private Facebook group from approximately 32 weeks gestation to 6 months postpartum. The Facebook group will provide a) evidence-based education through videos and other multi-media supporting best practices for infant safe sleep and b) an online community and social network of other pregnant WIC clients and new parents.
Study: NCT05706233

Intervention type: PROCEDURE
Intervention: Erector Spina Plane Group
Description: ESPB had been applied postoperatively: from T8 level, 20mL bupivacaine %0,5 + 5ml %2 lidocaine was applied.

Intervention type: PROCEDURE
Intervention: IV analgesic intervention
Description: IV analgesics had been applied: All meperidine boluses are dosed in line with the pain intensity as follows: 10 mg if NRS \> 3, 20 mg if NRS \> 5, 30 mg if NRS \> 8. If NRS score is not reduced at least 20% when compared to prior one, additional meperidine bolus is applied.
Study: NCT05767658

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding
Description: Participants will be part of a private Facebook group from approximately 32 weeks gestation to 6 months postpartum. The Facebook group will provide a) evidence-based education through videos and other multi-media supporting best practices for breastfeeding and b) an online community and social network of other pregnant WIC clients and new parents.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding
Description: Participants will be part of a private Facebook group from approximately 32 weeks gestation to 6 months postpartum. The Facebook group will provide a) evidence-based education through videos and other multi-media supporting best practices for breastfeeding and b) an online community and social network of other pregnant WIC clients and new parents.