TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05693337

Intervention type: DEVICE
Intervention: Forward Looking Infrared Radar (FLIR) thermal imaging
Description: The FLIR camera will collect temperature recordings pre-procedure and 5 minutes post-procedure, which will be used to calculate a delta T to assess achievement of a successful sympathetic block.
Study: NCT06624137

Intervention type: DRUG
Intervention: Serotonergic Psychedelic
Description: Any serotonergic or classic psychedelic that exhibits mainly Serotonin 2A receptor (5-HT2AR) agonism and is judged to produce subjectively similar effects.

Intervention type: DRUG
Intervention: Placebo
Description: Matched Placebo
Study: NCT06597487

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Full pulpotomy
Description: The patients will receive full pulpotomy as follows:~-Under rubber dam isolation, the operator will perform caries removal, complete the access cavity preparation, achieve hemostasis from all canals, and apply the bioceramic material. The operator will seal the cavity with glass ionomer restoration.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional root canal treatment
Description: The patients will receive conventional root canal treatment, which is the gold standard treatment protocol in cases with irreversible pulpitis.
Study: NCT06682234

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: obeldesivir
Description: Tablets administered orally
Study: NCT06684080

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A care bundle
Description: 1. Risk evaluation for PPH and Reserve plan;~2. Assess blood loss using Estimated Blood Loss Form and amnion fluid collection drape;~3. Satisfy any of the following conditions: i. If the estimated blood loss reaches 500ml but is less than 1000ml, and any of the following abnormal indicators are present; ii. If the estimated blood loss reaches 1000ml, no other indicators need to be considered: 1） Lack of uterine contractions 2） Persistent bleeding 3）Shock index (heart rate/systolic blood pressure) was greater than 0.9 Initiate the following protocols①, ②, ③, ④~   * Maintain uterus tone (Administration of Oxytocin and second-line medications to promote uterine contraction)~     * Intravenous infusion ③ Administered tranexamic acid ④ Multi-methods and Multi-disciplinary
Study: NCT06235203

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: endoscopic surgery
Description: The tumor was resected by endoscopic nasopharyngectomy.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endoscopic surgery
Description: The tumor was resected by endoscopic nasopharyngectomy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant therapy,Toripalimab Injection and Gemcitabine based therapy
Description: Two courses of Toripalimab Injection and two courses of Toripalimab Injection and Gemcitabine based chemotherapy were given before endoscopic surgery.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adjuvant therapy in experimental group,Toripalimab Injection and Gemcitabine based therapy
Description: Eight courses of Toripalimab Injection and two to four courses of chemotherapy, or until unacceptable side effects.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adjuvant therapy in control group,Toripalimab Injection and Gemcitabine based therapy
Description: Ten courses of Toripalimab Injection and four to six courses of chemotherapy,or until unacceptable side effects.
Study: NCT06442956

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rapid Heat Condition
Description: The heat condition is the intervention. Personal protective equipment will be used to create the rapid heat stress condition, resulting in a rapid rise in core temperature. This will be in combination with the physiological heat produced by the treadmill protocol.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Gradual Heat Condition
Description: The gradual heat condition is the control. Physiological heat will be produced by exercise on a treadmill, and light exercise clothing will help moderate the rise in core temperature.
Study: NCT06485076

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early Palliative Care
Description: see previous description
Study: NCT06701994

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Innovative Kinesiotaping Bandage Group
Description: This group will receive an innovative kinesiotaping bandage developed specifically for this study. The kinesiotape will be applied directly to the skin on the ankle, combining water resistance with restrictive properties to stabilise the joint while maintaining flexibility. Unlike traditional tape, the kinesiotape is designed to perform well in aquatic conditions, making it suitable for triathlon demands. It provides joint support while allowing a greater range of motion, aiming to enhance performance across all phases of the sport. To maintain blinding, the bandage will also be covered with an opaque stocking.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Tape Bandage Group
Description: Participants in this group will receive a traditional ankle bandage using functional tape. The bandage is applied directly to the skin and is designed to restrict ankle inversion and plantar flexion, providing stability to prevent recurrent injuries. Traditional tape bandages are widely used in sports due to their effective joint stabilisation. However, they have significant limitations in aquatic environments as they lack water resistance, which makes them less effective during the swimming phase of triathlons. The bandage will be covered with an opaque stocking to ensure blinding, preventing participants or evaluators from identifying the type of intervention.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Bandage Group
Description: Participants in this group will receive a placebo bandage consisting of a simple gauze wrap applied directly to the ankle. The gauze lacks stabilising or therapeutic properties and is used as a control to account for potential placebo effects. Although it mimics the application process of the other bandages, it does not provide functional or structural support to the ankle joint. An opaque stocking will cover the gauze to ensure that neither participants nor evaluators can distinguish the placebo bandage from the others, maintaining the integrity of the blinding process.
Study: NCT06682299

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transmagnetic Stimulation
Description: TMS will be given for the maintenance treatment of treatment resistant depression following successful course of ECT (8-12 treatments).

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electroconvulsive Therapy
Description: Patients will remain in standard of care treatment and receive maintenance ECT treatments for treatment resistant depression
Study: NCT06722222

Intervention type: PROCEDURE
Intervention: Gao's triple eversion carotid endarterectomy
Description: The carotid sheath is dissected in front of the sternocleidomastoid muscle to expose sufficient lengths of the CCA, ECA, and ICA. After raising the systolic blood pressure to 180 mmHg and intravenously injecting 1 mg/kg heparin, the superior thyroid artery is lapped and severed, and the CCA is occluded proximally to the CCA plaque, based on the plaque location shown by preoperative CTA and by intraoperative arterial exploration. Subsequently, the ECA and ICA are blocked individually. The ICA is cut diagonally at the CCA fork and the ECA is transected approximately 5 mm above its beginning. The plaque is removed with tweezers after eversion of the ICA. This process is repeated for the ECA. Finally, the long segment of plaque in the CCA is stripped proximally, followed by thorough removal of the debris on the peeling surface using heparin irrigation.
Study: NCT05031702

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Camellia Sinensis leaf extract
Description: 2 tablets per day of 150 mg (1 before lunch and 1 before dinner)

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 tablets per day of 150 mg (1 before lunch and 1 before dinner)
Study: NCT04603352

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hip Helpers home program
Description: Home program: Infants will wear Hip Helpers 30 minutes, twice per day.
Study: NCT05199571

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ofatumumab
Description: Solution for injection in an autoinjector (pre-filled pen) containing 20 mg ofatumumab
Study: NCT06431802

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional intervention
Description: A nursing specialist with extensive clinical and teaching experience will provide on-site course training. The training will cover topics related to pain and pain assessment, such as: pain definition, types, physiological mechanisms, performance, pain assessment tools, and frequency of pain assessment. Interventions will be provided once a week for 4 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Platform intervention
Description: Using a pre-assigned account to log in to the platform, read the guidance instructions and enter the platform to start training. Basic knowledge of pain and pain assessment can be learnt through the Learning Resources module on the platform, and pain assessment training can be conducted through the Pain Assessment Exercise module. During pain assessment training the platform provides instant feedback based on the participant's exercises. Interventions will be completed in 4 weeks.
Study: NCT06386770

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine Injection [Precedex]
Description: Group ΙI (group DL): erector spinae block will receive 30 ml (28 ml bupivacaine 0.25% plus dexamedetomedine (0.5µg/kg) diluted in 2ml normal saline Na cl 0,9% ) + 10ml IV normal saline will be injected over 10 min after 10 min from the induction of general anesthesia

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: .Group Ι Block only (group BO) (control group): erector spinae block will receive 30 ml ( 28 ml bupivacaine 0.25% +2ml normal saline Na cl 0,9 %) +10ml IV normal saline will be injected over 10 min after 10 min from the induction of general anesthesia

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine in 0.9 % NaCl 200 Mcg/50 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)
Description: Group III (group D IV): erector spinea block will receive 30 ml ( 28 ml bupivacaine 0.25% +2ml normal saline Na cl 0,9%) + dexamedetomedine (0.5µg/kg) diluted with 10 ml normal saline IV infusion by syringe pump over 10 min after 10 min from the induction of general anesthesia.
Study: NCT05735067

Intervention type: OTHER
Intervention: Blood sample collection
Description: 5 ml of blood samples were withdrawn from RRMS patients

Intervention type: OTHER
Intervention: Blood sample collection
Description: 5 ml of blood samples were withdrawn from RRMS patients
Study: NCT06005766

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Metacognitive Skills Training (MCT)
Description: The goal of the metacognitive skills training group developed by Moritz and co. is to strengthen the social and metacognitive skills of the patients participating in the group. The group consists of 10 sessions during which exercises and discussion are emphasized. The themes of the group sessions are, for example, jumping to conclusions -bias, empathy, and memory. Detailed information is available from the MCT website (https://clinical-neuropsychology.de/metacognitive_training-psychosis/). Overall there is meta-analysis-level evidence for the moderate effectiveness of MCT on positive symptoms of psychotic illnesses, such as delusions. Prior studies have argued that the unique factor underpinning MCT's efficacy is its impact on various cognitive biases, and that participating in the group especially reduces patients' tendency to jump to conclusions, which is a cognitive style associated with delusions and deficits in social perception and reasoning.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as usual
Description: Medicinal treatment deemed appropriate by the attending physician, psychiatric ward treatment, and others forms of treatment recommended to the patients based on their treatment plans (e.g., work therapy, dialectical behavior therapy, talk therapy)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: Medicinal treatment deemed appropriate by the attending physician, psychiatric ward treatment, and others forms of treatment recommended to the patients based on their treatment plans (e.g., work therapy, dialectical behavior therapy, talk therapy)
Study: NCT05858996

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pain-CPG-EIT
Description: Following randomization champions and stakeholder team members from the communities will be identified. The investigators will recommend the following individuals to be members of the stakeholder team: a nurse in a leadership position (e.g., director of nursing); the designated champion(s); nursing home administrator; physician/medical director, nurse practitioner and/or physician assistant; unit nurse; nursing assistant; activity staff; social worker; pharmacist; and rehabilitation therapists.~Following the first stakeholder team meeting, treatment communities will be provided with a research nurse facilitator to work 8 hours weekly during months one and two and then for four hours weekly starting in month three for a total of 12 months to provide the four components of the PAIN-CPG-EIT.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pain-CPG-Education Only
Description: The Pain-CPG-Education only group will be provided with the same education as used in Component II of the Pain-CPG-EIT intervention. The education will be provided based on the preferences of the community (this may be face-to-face; online; or via handouts).
Study: NCT05203926

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MRI scan
Description: Subjects will undergo T1 and STIR sequence MRI of sacroiliac joints (SIJ ) (pelvis MRI) as well as SIJ plain X-ray for assessment of radiographic sacroiliitis. The study will utilize 3 Tesla with phased array coil to maximize signal to noise ratio for image quality. This is a single procedure, which takes about 60 minutes. 1 radiologists, blinded to all clinical information, will evaluate for presence of acute and structural lesions. Images will be scored for presence or absence of acute and/or structural lesions in a global manner.
Study: NCT05670899

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CAD PEEK frame-work
Description: Construction of PEEK framework will be done conventionally by lost wax technique using a vacuum press device. The wax pattern will be invested in a mold using special investment. Then it will be heated and melted to produce a mold into which PEEK will be vacuum pressed. The framework will be fitted on the master cast

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CAD PEEK frame-work
Description: Construction of PEEK framework will be done conventionally by lost wax technique using a vacuum press device. The wax pattern will be invested in a mold using special investment. Then it will be heated and melted to produce a mold into which PEEK will be vacuum pressed. The framework will be fitted on the master cast
Study: NCT05786690

Intervention type: OTHER
Intervention: Interventions
Description: the temporospatial and kinematic gait characteristics

Intervention type: OTHER
Intervention: Interventions
Description: the temporospatial and kinematic gait characteristics
Study: NCT06484478

Intervention type: OTHER
Intervention: Wearable technology monitoring
Description: Observational study (no intervention delivered)
Study: NCT06488859

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive Affect Treatment
Description: Sessions 1-8: Pleasurable activities + imaginal recounting and reinforcement of positive mood effects

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Positive Affect Treatment and Negative Affect Treatment
Description: Sessions 1-4: Pleasurable activities + imaginal recounting and reinforcement of positive mood effects Sessions 5-8: Exposure therapy to feared or avoided situations, sensations, or memories
Study: NCT05530551

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Antibiotic dosage practice
Description: Patient inclusion starts day one, cross-over of departments from treatment A (single-dose) to B (multiple-dose) or vice versa after one year and end of inclusion happens after 2 years.~All centers in Denmark use either Cloxacillin/Dicloxacillin, Cefuroxime or both drugs as standard prophylactic antibiotic practice for THA. In cases of cephalosporin allergy or general beta lactam allergy, the antibiotic clindamycin may be administered.~In this trial, patients will be administered the standard prophylactic antibiotic practice of either single-dose (A) or multiple-doses (B) of antibiotics administered at each respective cluster that respective year. Both practices of dose administration for antibiotic prophylaxis (i.e. single- or multiple-dose) follow current standards of treatment and are based on present clinical practice guidelines.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Antibiotic dosage practice
Description: Patient inclusion starts day one, cross-over of departments from treatment A (single-dose) to B (multiple-dose) or vice versa after one year and end of inclusion happens after 2 years.~All centers in Denmark use either Cloxacillin/Dicloxacillin, Cefuroxime or both drugs as standard prophylactic antibiotic practice for THA. In cases of cephalosporin allergy or general beta lactam allergy, the antibiotic clindamycin may be administered.~In this trial, patients will be administered the standard prophylactic antibiotic practice of either single-dose (A) or multiple-doses (B) of antibiotics administered at each respective cluster that respective year. Both practices of dose administration for antibiotic prophylaxis (i.e. single- or multiple-dose) follow current standards of treatment and are based on present clinical practice guidelines.
Study: NCT05552651

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envafolimab
Description: 300mg,sc,d1,Q3W;

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin-Bound Paclitaxel
Description: 130mg/m2,iv,D1,D8,Q3W

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: AUC=5, iv,D1,Q3W
Study: NCT06240962

Intervention type: OTHER
Group type: OTHER
Intervention: Strength Training
Description: They will receive the strength training only (6 weeks, 3 sessions/week) that feature training modifications to help control injury-related symptoms.

Intervention type: OTHER
Group type: OTHER
Intervention: Mindfulness Exercise
Description: They will receive mindfulness-exercise for 6-week mindfulness intervention in addition to the strength training protocol.
Study: NCT04967313

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Change Techniques
Description: Four behavioral changes techniques (BCTs) will be administered to participants in random order. The BCTs are defined as follows:~1. Goal setting: set or agree on a goal defined in terms of behavior to be achieved. Example: Set the goal of walking 2,000 steps more per day.~2. Action planning: prompt detailed planning of performance of behavior (must include a setting \[walking to the mailbox\], frequency, duration, and intensity. Example: Develop a plan to walk today.~3. Self-Monitoring of behavior: establish a method for person to monitor and record their number of steps based on their Fitbit. Example: Did you check your Fitbit and record daily total number of steps?~4. Feedback on behavior: Monitor and provide informative or evaluative feedback on performance of the behavior (e.g. form, frequency, duration, intensity). Example: You walked 6,000 steps today. This is 1,000 steps above your baseline.
Study: NCT05547230

Intervention type: OTHER
Intervention: questionnaires
Description: The same tests will be applied to all participants in an objective way.
Study: NCT02735083

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: UCART19 follow-up
Description: UCART19 will not be administered during the study period. Patients who will be rolled-over from the parent study to this long term follow-up study, have previously received UCART19. The roll-over occurs at the end of the parent study, or at any time after UCART19 administration, in case of premature discontinuation from the parent study.
Study: NCT05549973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anlotinib Hydrochloride Capsule
Description: Anlotinib hydrochloride is a muti-target tyrosine kinase inhibitor.
Study: NCT04578990

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Walking intervention
Description: It will consist of performing the Treadmill training progression for 36-72 sessions. 3 sessions of 60 minutes, will be held weekly.~Depending on the data obtained in Visit 1, the speed will be determined for each patient and the degree of the initial slope that is comfortable when walking until it induces symptoms of moderate intermittent claudication. The progression of the intensity of the speed and incline of the slope will be increased progressively and individually for each patient.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strength intervention
Description: The training program consists of performing a training program with resistance exercises for 36-72 weeks. There will be 3 weekly sessions of 60 minutes, where exercises with resistance will be applied. The same guidelines will be followed as in the walking exercise, but in this case, applying force stimuli. If symptoms of moderate intermittent claudication occur (3-4) based on the Claudication Symptom Rating Scale in 5-10 minutes, a period of rest (sitting or standing) will be performed until the pain disappears at the level of the lower limb. This sequence will be repeated until the strength training session is completed. The progression of force stimuli will be increased weekly depending on the subjective perception of the patient's effort and according to the guidelines set by our group of investigation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Concurrent intervention
Description: The training program consists of alternating strength and resistance stimuli in the same session for 36-72 weeks. There will be 3 weekly sessions of 60 minutes, where exercises with resistance will be applied for 35 minutes and to complete the 60 minutes, the same guidelines will be followed as in the walking exercise, applying resistance stimuli. If claudication symptoms occur moderate intermittent (3-4) based on the Claudication Symptom Rating Scale in 5-10 minutes, a period of rest (sitting or standing) will be performed until the pain in the lower extremity disappears. This sequence will be repeated until the 20 minutes established to end the session are completed concurrent training. The progression of the strength and resistance stimuli will be increased weekly depending on the perception subjective effort of the patient and according to the guidelines established by our research group.