TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04884412

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery under general anesthesia with experimental targeting
Description: Surgery will be performed under general anesthesia. The electrodes will be inserted directly on the targets without MER, with PARKEO_2 targets provided by the Bordeaux University Hospital, based on the machine-learning model developed in Bordeaux.
Study: NCT06294470

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Colonic transit time
Description: Patients ingested capsules with 24 radiopaque markers and underwent standing abdominal radiographs on Day 3 and Day 5. Over 80% expulsion within five days was considered normal, while retention indicated defecatory obstruction.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Stapled hemorrhodopexy
Description: Circumferential stapled hemorrhoidopexy with a 34mm circular stapler is a surgical procedure used to treat mucohemorrhoidal prolapse.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stapled hemorrhodopexy
Description: Circumferential stapled hemorrhoidopexy with a 34mm circular stapler is a surgical procedure used to treat mucohemorrhoidal prolapse.
Study: NCT04884412

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Usual Surgery
Description: In the control group, surgery will be performed as usual in each centre under local or general anaesthesia. This group represents the current state of the art of deep brain stimulation in these centres.
Study: NCT05712772

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blue Light
Description: Blue light exposure

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blue Light
Description: Blue light exposure
Study: NCT05161390

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM-302 Injection
Description: LM-302 Injection with dose escalation stage of different dose levels, as well as dose expansion stage with recommended dose level from dose escalation stage.
Study: NCT05712772

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Red Light
Description: Red light exposure

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Red Light
Description: Red light exposure
Study: NCT04976725

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Therapy
Description: 75 individuals will be included in our study, including 3 groups: control group (N= 25), osteopathic manipulative technique (n= 25), myofascial relaxation group (n=25). Which group of individuals will be determined by randomizing them with closed envelope method.~Osteopathic Manipulative Therapy and myofascial relaxation treatment applications will be applied 2 days a week, for periods of 30 min for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Therapy
Description: 75 individuals will be included in our study, including 3 groups: control group (N= 25), osteopathic manipulative technique (n= 25), myofascial relaxation group (n=25). Which group of individuals will be determined by randomizing them with closed envelope method.~Osteopathic Manipulative Therapy and myofascial relaxation treatment applications will be applied 2 days a week, for periods of 30 min for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Therapy
Description: 75 individuals will be included in our study, including 3 groups: control group (N= 25), osteopathic manipulative technique (n= 25), myofascial relaxation group (n=25). Which group of individuals will be determined by randomizing them with closed envelope method.~Osteopathic Manipulative Therapy and myofascial relaxation treatment applications will be applied 2 days a week, for periods of 30 min for 4 weeks.
Study: NCT05696600

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Scaling and root planing and open flap debridement
Description: Scaling and root planing involves removal of plaque and calculus.~Open Flap debridement involves reflection of full thickness mucoperiosteal flap, thorough debridement of the surgical site and approximation and suturing of the flap at the original position.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Scaling and root planing and open flap debridement
Description: Scaling and root planing involves removal of plaque and calculus.~Open Flap debridement involves reflection of full thickness mucoperiosteal flap, thorough debridement of the surgical site and approximation and suturing of the flap at the original position.
Study: NCT04559230

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacituzumab Govitecan
Description: Sacituzumab Govitecan will be administered by IV infusion over 3 hours for first administration and over 1 hour if tolerated. Subjects will be allowed to continue treatment until they have evidence of significant treatment-related toxicity or progressive disease.
Study: NCT04820218

Intervention type: DEVICE
Group type: OTHER
Intervention: With Try-on glasses
Description: Subjects will be asked to measure their visual acuity with their try-on glasses
Study: NCT05352243

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Expressive Disclosure
Description: Prior to each writing session, participants will receive general instructions for completing the writing (e.g., write continuously for 20 minutes, do not worry about grammar, sentence structure, repetition), and be reminded that their writing will remain confidential. Three writing sessions will be spaced 1-2 weeks apart. A weekly writing prompt will instruct participants to write about their deepest thoughts and feelings surrounding their bereavement experience.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Expressive Helping
Description: Prior to each writing session, participants will receive general instructions for completing the writing (e.g., write continuously for 20 minutes, do not worry about grammar, sentence structure, repetition), and be reminded that their first two writing will remain confidential, and their final essay will be de-identified before being provided to newly bereaved young adults. Three writing sessions will be spaced 1-2 weeks apart. In the first two writing sessions, participants will receive a writing prompt that will instruct them to write about their deepest thoughts and feelings surrounding their bereavement experience. For the final writing session, participants will receive a writing prompt instructing them to provide advice and support for a newly bereaved young adult.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Fact-Writing
Description: Prior to each writing session, participants will receive general instructions for completing the writing (e.g., write continuously for 20 minutes, do not worry about grammar, sentence structure, repetition), and be reminded that their writing will remain confidential. Three writing sessions will be spaced 1-2 weeks apart. A weekly writing prompt will instruct participants to write objectively about different time frames (e.g., routine for getting up in the morning, routine for going to sleep at night).
Study: NCT05776667

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiation Therapy
Description: Participants will receive preoperative 5-day HFRT (30Gy/5fx once daily over consecutive weekdays) followed by standard of care wide local excision 2-6 weeks later.
Study: NCT06233825

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Omega-3 Fatty Acids and Essential Amino Acids
Description: Oil consumed as capsules. EAA come as powder to be mixed with water before drinking. 4 g of leucine per EAA dose.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Safflower Oil and Non-Essential Amino Acids
Description: Oil consumed as capsules. NEAA are isonitrogenous to intervention condition. Both supplement types are isoenergetic to intervention. NEAA come as powder to be mixed with water before drinking.
Study: NCT06380569

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: KF-STRIDE®
Description: Treatment group will receive 10 web based sessions of a strength-based training tool (once or twice a week). Sessions are approximately 60 minutes long.
Study: NCT05724992

Intervention type: GENETIC
Group type: OTHER
Intervention: Saliva swab testing
Description: 41 pancreatic cancer predisposition genes will be tested through a saliva-based swab
Study: NCT05623527

Intervention type: DEVICE
Intervention: cardiac electronic implants
Description: Cardiac electronic implants(CIED) includes permanent pacemaker (PPM), implantable cardioverter defibrillator (ICD), three-chamber pacemaker for cardiac resynchronization therapy defibrillator, lead free pacemaker, etc.

Intervention type: DEVICE
Intervention: cardiac electronic implants
Description: Cardiac electronic implants(CIED) includes permanent pacemaker (PPM), implantable cardioverter defibrillator (ICD), three-chamber pacemaker for cardiac resynchronization therapy defibrillator, lead free pacemaker, etc.

Intervention type: DEVICE
Intervention: cardiac electronic implants
Description: Cardiac electronic implants(CIED) includes permanent pacemaker (PPM), implantable cardioverter defibrillator (ICD), three-chamber pacemaker for cardiac resynchronization therapy defibrillator, lead free pacemaker, etc.
Study: NCT05968378

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard healthy eating advice
Description: Subjects in this group will be provided with standard healthy eating advice according to the Irish National Healthy Eating Guidelines and Food Pyramid and will be asked to follow this advice for 8-weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: eTRE plus Mediterranean diet
Description: Subjects in this group will be asked to consume all meals between 8am - 4pm and to adhere to a Mediterranean style diet daily for 8-weeks.
Study: NCT06432322

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine nasal spray
Description: Nasal spray solution, 56mg (28mg per nostril), intranasal

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Nasal spray solution, 0.9% NaCl, intranasal
Study: NCT05399277

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban
Description: 15mg oral daily for 7 days
Study: NCT05110027

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enpatoran
Description: Participants will receive single oral dose of enpatoran tablet on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enpatoran
Description: Participants will receive single oral dose of enpatoran tablet on Day 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]enpatoran microtracer
Description: Participants will receive single oral dose of non-labeled enpatoran solution spiked with microtracer of \[14C\]enpatoran on Day 1 of Period 1.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]enpatoran microdose
Description: Participants will receive intravenous \[14C\]enpatoran microdose administered at 1.5 hours after the oral dose of enpatoran on Day 1 of Period 2.
Study: NCT05076084

Intervention type: PROCEDURE
Intervention: QUICK questionnaire and 6 additional questions
Description: QUICK questionnaire and 6 additional questions

Intervention type: OTHER
Intervention: Retrospective collection of clinical data from the patients' medical records
Description: Retrospective collection of clinical data from the patients' medical records
Study: NCT05565027

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dynamic digital radiography
Description: The use of advanced dynamic X-ray photography and acquisition technology can obtain high-definition dynamic lung images of patients throughout the respiratory cycle for analysis.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pneumotachograph
Description: The pneumotachograph monitors the flow rate, and the lung volume is calculated by integrating.
Study: NCT05489042

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: 5 Sessions of rTMS - brief single pulse TMS or short TMS pulse bursts consisting of 2-5 pulses delivered per second at a standard intensity. If a brief single pulse TMS is applied, a standard single pulse TMS procedure will be used - This procedure consists of 10 trains of 180 seconds duration and each train will be separated by at least 30 seconds. If short TMS pulse bursts are applied, a standard theta-burst TMS procedure will be used - This procedure consists of TMS triplets (i.e., 3 pulses) that repeat for 10 trains of a total duration of 40-190 seconds and these bursts will be separated by at least 6 seconds and each train will be separated by at least 30 seconds

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham rTMS
Description: 5 sessions of sham rTMS
Study: NCT05901974

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax orally once daily (100 mg d1, 200 mg d2, 400 mg d3-28);

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: azactidine
Description: azacitidine 75 mg/m2 subcutaneously once daily on days 1-7
Study: NCT04616534

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy (dose expansion cohort only)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diagnostic Imaging
Description: Undergo medical imaging scans

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elimusertib
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Given IV
Study: NCT05203185

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary Embolism Risk Kalculator (PERK)
Description: Nudges are applications of behavioral science, defined as positive reinforcement and indirect suggestions that have a non-forced effect on decision making. Nudges will be to the PE CALC CDS tool to develop the new CDS tool, PERK.
Study: NCT05869474

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Iodine125-Seeds implantation
Description: Endoscopic ultrasound-guided intratumoral iodine125-Seeds implantation

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gem/nab-P Chemotherapy
Description: nab-paclitaxel (125 mg per square meter of body-surface area) followed by gemcitabine (1000 mg per square meter) on days 1, 8 every 3 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gem/nab-P Chemotherapy
Description: nab-paclitaxel (125 mg per square meter of body-surface area) followed by gemcitabine (1000 mg per square meter) on days 1, 8 every 3 weeks
Study: NCT05172570

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gabapentin
Description: Gabapentin is a common medication used preoperatively and postoperatively as part of multimodal analgesia to help with acute pain.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gabapentin
Description: Gabapentin is a common medication used preoperatively and postoperatively as part of multimodal analgesia to help with acute pain.
Study: NCT05147844

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Toripalimab: 240mg, iv. Q3W for 1 year or until disease progression/intolerable toxicity~Radiotherapy:~Newly diagnosed patients: IMRT for nasopharynx lesions and cervical lymph nodes, pGTVnx 70 Gy, pGTVnd 99Gy, pCTV1, 60 Gy, pCTV2, 54 Gy, 33 times, completed in 7 weeks.~Relapsed patients: IMRT for nasopharynx lesions and cervical lymph nodes, pGTVnx 60Gy, pGTVnd 60Gy, 20-25 times, completed in 4-5 weeks.~Newly diagnosed and relapsed patients: SBRT for oligometastatic lesions, pGTV 25-40 Gy, 3-5 times, completed in 1-2 weeks.
Study: NCT06092476

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Revita® DMR Treatment
Description: The Revita® System is an endoscopic treatment consisting of a single catheter and console designed to lift the duodenal mucosa with saline followed by controlled circumferential hydrothermal ablation of the mucosa. For this study Revita® DMR procedure will be conducted as follows:~DMR Treatment Paradigm 1- After initial 2 Lift and Ablate step, remaining Lift: Ablate steps will be conducted in 1:1 manner.
Study: NCT04948047

Intervention type: DIAGNOSTIC_TEST
Intervention: Pathological examinations as the golden diagnosis criteria
Description: Pathological diagnosis, as the golden standard for diagnosing pulmonary nodules, is achieved by two experienced pathologists and validated by the third senior pathologist.
Study: NCT06092476

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham procedure
Description: The sham control for the Revita DMR procedure.
Study: NCT05108129

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: M-TAPA block
Description: After tracheal intubation, a high-frequency linear probe will be placed in the sagittal direction at the 10th costal margin, and transversus abdominis, internal oblique, and external oblique muscles will be identified. A block needle will be inserted with in-plane technique and 25 ml 0.25% bupivacaine will be injected between the transversus abdominis muscle and the lower aspect of the costal cartilage. The same procedure will be repeated on the contralateral side.~Standard perioperative and postoperative multimodal analgesia The pain intensity during rest and motion will be evaluated with the 0-10 Numeric Rating Scale (NRS). Patients will receive standard multimodal analgesia comprising paracetamol, dexketoprofen, and tramadol.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: OSTAP block
Description: The patients will receive oblique subcostal TAP block in the supine position immediately after the endotracheal intubation. The anesthesiologist of the operating room will place the ultrasound with a linear probe subcostally and from the xiphoid to the right iliac crest obliquely. Rectus abdominis muscle and underlying transversus abdominis muscle, will be identified near the costal margin. The needle will be directed to the transversus abdominis fascia. Local anesthetic solution of 25 ml 0.25% will be injected to between rectus abdominis and transversus abdominis muscles along the oblique subcostal line. The same procedure will repeated to the contralateral side.~Standard perioperative and postoperative multimodal analgesia The pain intensity during rest and motion will be evaluated with the 0-10 Numeric Rating Scale (NRS). Patients will receive standard multimodal analgesia comprising paracetamol, dexketoprofen, and tramadol.
Study: NCT04472559

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-acupressure
Description: Self-acupressure
Study: NCT06473805

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: VISTA technique and 3D printed PMMA implant
Description: Intraoral scanning and radiographic examination (CBCT) will be performed to assess the anatomy of the sub nasal area and plan the position, size and thickness of PMMA implant The data will be transferred to 3D planning software to create digital model that fit in the defect followed by 3D printing of the implant using VISTA technique

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: VISTA technique and 3D printed PEEK implant
Description: Intraoral scanning and radiographic examination (CBCT) will be performed to assess the anatomy of the subnasal area and plan the position, size and thickness of PEEK implant The data will be transferred to 3D planning software to create digital model that fit in the defect followed by 3D printing of the implant using VISTA technique
Study: NCT04948047

Intervention type: DIAGNOSTIC_TEST
Intervention: Breath test combined with computed tomography
Description: Exhaled breath of each participant will be collected with Tedlar bags. The volatile organic compounds will be detected by a high-resolution high-pressure photon ionization time-of-ﬂight mass spectrometry (HPPI-TOFMS).~The Imaging markers of pulmonary nodules, including the size, three-dimensional shape, and appearance characteristics, are derived from the chest computed tomography within 2 weeks before surgery resection.

Intervention type: DIAGNOSTIC_TEST
Intervention: Breath test combined with computed tomography
Description: Exhaled breath of each participant will be collected with Tedlar bags. The volatile organic compounds will be detected by a high-resolution high-pressure photon ionization time-of-ﬂight mass spectrometry (HPPI-TOFMS).~The Imaging markers of pulmonary nodules, including the size, three-dimensional shape, and appearance characteristics, are derived from the chest computed tomography within 2 weeks before surgery resection.
Study: NCT05502913

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: Recipients will undergo bowel preconditioning with antibiotics (Rifaximin) following randomization.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FMT (Fecal Microbiota Transplantation)
Description: FMT involves the transplantation of fecal bacteria from a screened donor to a recipient. This will be achieved per os in the form of a capsule containing freeze-dried stool obtained from the donor.
Study: NCT05882552

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Tilted Gaze Target Tast
Description: Tilted gaze target tast is playing a small animated video with a visual mobile device at a distance of 33 cm and 3 m, respectively, to determine the optimal angle of head position improvement and the spatial tilt angle of the screen relative to the orthostatic position.It will be conducted during the first visit. Preoperative intervention will also be conducted before surgery. Postoperative interventions will be conducted at one day, one month, and six months after surgery.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Tilted Gaze Target Tast
Description: Tilted gaze target tast is playing a small animated video with a visual mobile device at a distance of 33 cm and 3 m, respectively, to determine the optimal angle of head position improvement and the spatial tilt angle of the screen relative to the orthostatic position.It will be conducted during the first visit. Preoperative intervention will also be conducted before surgery. Postoperative interventions will be conducted at one day, one month, and six months after surgery.

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Examination Methods
Description: The conventional examination methods include oculomotor examination, Bielschowsky head tilt test, alternate prism cover test, prism adaptation test, and monocular cover test. They will be conducted during the first visit. Preoperative intervention will also be conducted before surgery.Postoperative interventions will be conducted at one day, one month, and six months after surgery.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Conventional Examination Methods
Description: The conventional examination methods include oculomotor examination, Bielschowsky head tilt test, alternate prism cover test, prism adaptation test, and monocular cover test. They will be conducted during the first visit. Preoperative intervention will also be conducted before surgery.Postoperative interventions will be conducted at one day, one month, and six months after surgery.