Study: NCT02007434

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deoxycholic Acid Injection
Description: Formulated as an injectable solution containing deoxycholic acid at a concentration of 10 mg/mL.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Phosphate buffered saline placebo for injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Phosphate buffered saline placebo for injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Phosphate buffered saline placebo for injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Phosphate buffered saline placebo for injection

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Cold Compress
Description: A cold compress was applied to the injection area for 10 minutes before dosing and for 15 minutes after dosing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine / Epinephrine
Description: Lidocaine 4% topical cream applied 45 minutes prior to dosing across the area to be treated, followed by 0.4 mL SC injections of lidocaine HCl 1% / epinephrine 1:100,000 around the perimeter of the treatment area and across the treatment area in a regular pattern 25 minutes before dosing.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lidocaine / Epinephrine
Description: Lidocaine 4% topical cream applied 45 minutes prior to dosing across the area to be treated, followed by 0.4 mL SC injections of lidocaine HCl 1% / epinephrine 1:100,000 around the perimeter of the treatment area and across the treatment area in a regular pattern 25 minutes before dosing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine / Epinephrine
Description: Lidocaine 4% topical cream applied 45 minutes prior to dosing across the area to be treated, followed by 0.4 mL SC injections of lidocaine HCl 1% / epinephrine 1:100,000 around the perimeter of the treatment area and across the treatment area in a regular pattern 25 minutes before dosing.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lidocaine / Epinephrine
Description: Lidocaine 4% topical cream applied 45 minutes prior to dosing across the area to be treated, followed by 0.4 mL SC injections of lidocaine HCl 1% / epinephrine 1:100,000 around the perimeter of the treatment area and across the treatment area in a regular pattern 25 minutes before dosing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine / Epinephrine
Description: Lidocaine 4% topical cream applied 45 minutes prior to dosing across the area to be treated, followed by 0.4 mL SC injections of lidocaine HCl 1% / epinephrine 1:100,000 around the perimeter of the treatment area and across the treatment area in a regular pattern 25 minutes before dosing.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lidocaine / Epinephrine
Description: Lidocaine 4% topical cream applied 45 minutes prior to dosing across the area to be treated, followed by 0.4 mL SC injections of lidocaine HCl 1% / epinephrine 1:100,000 around the perimeter of the treatment area and across the treatment area in a regular pattern 25 minutes before dosing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Loratadine
Description: Loratadine 10 mg orally from Day -7 until Day 7

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Loratadine
Description: Loratadine 10 mg orally from Day -7 until Day 7