Study: NCT00283816

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Metformin 500 mg. tabs 2 tabs BID for duration of study

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oral Contraceptive Pill
Description: Yasmin, drospirenone and ethinyl estradiol 28 tablets~1 tab daily for duration of study

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral Contraceptive Pill
Description: Yasmin, drospirenone and ethinyl estradiol 28 tablets~1 tab daily for duration of study

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Lifestyle Management Program
Description: Subjects and a parent/guardian will participate in a series of classes for training in diet, exercise \& behavior modification skills on a regular weekly basis over the 24 week study

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle Management Program
Description: Subjects and a parent/guardian will participate in a series of classes for training in diet, exercise \& behavior modification skills on a regular weekly basis over the 24 week study

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Quality of Life Questionnaire
Description: Quality of Life questionnaire designed for women with Polycystic Ovary Syndrome. Questions concern health and health related issues Performed twice during study, at baseline and conclusion

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Quality of Life Questionnaire
Description: Quality of Life questionnaire designed for women with Polycystic Ovary Syndrome. Questions concern health and health related issues Performed twice during study, at baseline and conclusion

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Oral Glucose Tolerance Test
Description: Insulin response to a glucose challenge in an oral glucose tolerance test (OGTT), as measured by area under the curve (AUC). In this study we will administer an OGTT and calculate the AUC as a measure of insulin resistance.~Performed twice during study, at baseline and conclusion

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Oral Glucose Tolerance Test
Description: Insulin response to a glucose challenge in an oral glucose tolerance test (OGTT), as measured by area under the curve (AUC). In this study we will administer an OGTT and calculate the AUC as a measure of insulin resistance.~Performed twice during study, at baseline and conclusion

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Blood work
Description: Initial and conclusion blood draws include; comprehensive metabolic profile, CBC and platelet,hormonal assessment and lipids.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Blood work
Description: Initial and conclusion blood draws include; comprehensive metabolic profile, CBC and platelet,hormonal assessment and lipids.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Abdominal Ultra Sound
Description: transabdominal transducer, which contains integrated software for volume calculation will be used to assess ovarian volume.~Performed twice during study, at baseline and conclusion

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Abdominal Ultra Sound
Description: transabdominal transducer, which contains integrated software for volume calculation will be used to assess ovarian volume.~Performed twice during study, at baseline and conclusion

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Dual-energy x-ray absorptiometry (DEXA scan)
Description: Dual-energy x-ray absorptiometry (DEXA) will be used to assess percent body fat Performed twice during study, at baseline and conclusion

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dual-energy x-ray absorptiometry (DEXA scan)
Description: Dual-energy x-ray absorptiometry (DEXA) will be used to assess percent body fat Performed twice during study, at baseline and conclusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo capsules, two capsules BID