Study: NCT01336699

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator: 1 or 1.5 ml of sterile normal saline 0.9% added to 30 mL of 0.9% sterile normal saline, given orally.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator: 1 or 1.5 ml of sterile normal saline 0.9% added to 30 mL of 0.9% sterile normal saline, given orally.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator: 1 or 1.5 ml of sterile normal saline 0.9% added to 30 mL of 0.9% sterile normal saline, given orally.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator: 1 or 1.5 ml of sterile normal saline 0.9% added to 30 mL of 0.9% sterile normal saline, given orally.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator: 1 or 1.5 ml of sterile normal saline 0.9% added to 30 mL of 0.9% sterile normal saline, given orally.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs2
Description: WRSs2 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs2
Description: WRSs2 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs2
Description: WRSs2 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs2
Description: WRSs2 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs2
Description: WRSs2 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs3
Description: WRSs3 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs3
Description: WRSs3 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs3
Description: WRSs3 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs3
Description: WRSs3 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: WRSs3
Description: WRSs3 is a live, attenuated Shigella sonnei vaccine product, given orally at five escalating doses from 1x10\^3 colony-forming units (cfu) to 1x10\^7 cfu.