TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03380585

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Reciprocating single-file system
Description: After determining the working length, a flexible size 30 K-file will be inserted 1 mm beyond the WL and the apical foramen will be enlarged.The device in the experimental group moves in CW and CCW direction with different angles. It is a single-file endodontic file system. The intervention is reciprocating single-file system. A Reciproc single-file will be used for enlarging apical foramen. In the active comparator group, a continuous rotational multi-file system, ProTaper Next, will be used in enlarging apical foramen.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rotational multi-file system.
Description: After determining the working length, a flexible size 30 K-file will be inserted 1 mm beyond the WL and the apical foramen will be enlarged. In this group, a continuous rotational multi-file system, ProTaper Next, will be used in enlarging apical foramen.
Study: NCT04026477

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Immediate Universal Trauma-Informed Care and Cultural Humility Training
Description: Instructional video and workshop

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Waitlisted Universal Trauma-Informed Care and Cultural Humility Training
Description: Instructional video and workshop following waitlist period
Study: NCT02695199

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic varicocelectomy
Description: Traditional laparoscopic varicocelectomy assisted by laparoscopic Doppler ultrasound

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Microscopic Subinguinal varicocelectomy
Description: Infertile patients with clinically palpable varicoceles were selected to receive microscopic Subinguinal varicocelectomy
Study: NCT02003872

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spatz 3 intragastric balloon
Description: Intra gastric balloon implanted using gastroscopy
Study: NCT03138005

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: target SpO2 98-100%
Description: Prehospital, post-ROSC oxygen maintained at ≥10L/minute of oxygen (equivalent to \~100% oxygen) into SGA/ETT if hand ventilated or 100% (i.e. FiO2 of 1.0) oxygen settings if mechanically ventilated. Patients will continue on treatment to handover in the ED. Between arrival at ED and first ABG in ICU, the oxygen setting may then be decreased provided SpO2 is maintained between 98-100%.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: target SpO2 90-94%
Description: Prehospital, post-ROSC oxygen reduced initially to 4L/minute (i.e. approximately 70% oxygen) into SGA/ETT if hand ventilated or an air mix setting if mechanically ventilated. If oxygen saturation remains ≥94% for 5 minutes, the oxygen flow rate will be further reduced to 2L/minute (i.e. approximately 46% oxygen) and hand ventilated to target an oxygen saturation between 90-94%. This treatment will continue to patient handover in the emergency department. Between arrival at ED and first ABG in ICU, oxygen will be titrated to target a oxygen saturation of 90-94%.
Study: NCT02424968

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-Thymocyte Globulin
Description: Given per standard institutional practice

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Mofetil
Description: Given PO

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplant
Description: Undergo nonmyeloablative allogeneic HSCT

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic Cluster of Differentiation 8 (CD8)+ Memory T-cells
Description: Receive CD8+ memory T-cells via IV
Study: NCT03475992

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low-power microwave breast imaging system
Description: Investigate the capacity of microwave imaging to detect and characterise diagnosed palpable breast lump
Study: NCT02598921

Intervention type: RADIATION
Group type: OTHER
Intervention: three dimensional ultrasound

Intervention type: DEVICE
Group type: OTHER
Intervention: Office hysteroscopy
Study: NCT00121641

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Tablets, Oral, 500-2000 mg (as needed for rescue)
Study: NCT01732913

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Tablets administered orally twice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rituximab
Description: 375 mg/m\^2 administered intravenously weekly for 4 weeks, then every 8 weeks (up to a total of 8 infusions)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: 375 mg/m\^2 administered intravenously weekly for 4 weeks, then every 8 weeks (up to a total of 8 infusions)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Idelalisib
Description: 150 mg tablets administered orally twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Idelalisib
Description: 150 mg tablets administered orally twice daily
Study: NCT03228485

Intervention type: DEVICE
Intervention: MyBPH Care mobile app
Description: The application that will give daily medication reminders and via which the questionnaires can be filled out.
Study: NCT00697281

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OC000459
Description: Tablets twice daily for 8 days~Dose level 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OC000459
Description: Tablets twice daily for 8 days~Dose level 2

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OC000459
Description: Tablets twice daily for 8 days~Dose level 3

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OC000459
Description: Tablets twice daily for 8 days~Dose level 4

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Tablets twice daily for 8 days~Dose level 5
Study: NCT02831322

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Percutaneous coronary intervention
Description: Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous coronary intervention
Description: Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease
Study: NCT04356482

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: convalescent plasma
Description: In phase 1, different amounts of convalescent plasma will be evaluated depending on the severity of the case.~In phase 2, both clinical, laboratory, imaging and viral presence (effectiveness) and safety will be evaluated.
Study: NCT01409369

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RO4995819
Description: single oral dose

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RO4995819
Description: single oral dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: activated charcoal
Description: orally 3 times daily, Days 1-7
Study: NCT02904655

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: healthy diet
Description: Participants were provided meals and snacks for one month that represented a healthy diet that is high in unsaturated fats, approximating a Mediterranean diet
Study: NCT01146964

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MSSICS
Description: Manual super small incision cataract surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Phacoemulsification
Description: cataract surgery with Phacoemulsification
Study: NCT01171209

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Interferon-beta and human leukocyte Interferon-α
Description: One single injection of interferon(IFN)- β and one single injection of human leukocyte IFN-α (Multiferon® ) 6 MIU s.c. with 1-7 days follow-up.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Interferon-beta and human leukocyte Interferon-α
Description: One single injection of interferon(IFN)- β and one single injection of human leukocyte IFN-α (Multiferon® ) 6 MIU s.c. with 1-7 days follow-up.
Study: NCT02106728

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-Family Therapy
Description: Multi-Family Therapy is conducted once per week over the course of 8 weeks for 1.5 hours per session. Therapy is provided to a minimum of 3 families and a maximum of 6 families with the aid of two to three therapist group leaders. Group topics are set and cover material on eating disorder psychoeducation, care-giving styles, meal support, and relapse prevention.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Supportive Family Therapy
Description: Supportive Family Therapy is treatment as usual in the eating disorders program at TGH. Families meet independently with a therapist once per week for 1 hour per session. The length of the therapy and the topics of therapy are decided upon collaboratively with the therapist and the family.
Study: NCT01412203

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Action Schools! BC
Description: AS! BC applies a socioecological, whole school approach to promote healthy living within the elementary school context. Schools are provided with the tools and support needed to create customized action plans that promote physical activity (PA) and healthy living across six Action Zones (School Environment, Scheduled Physical Education (PE), Classroom Action, Family and Community, Extra-curricular, School Spirit). Generalist teachers receive training and resources to implement their Action Plan with the ultimate goal of providing students with 150 minutes of PA/week. The model is choice-based; teachers are asked to provide 15 additional minutes of PA/day within the Classroom Action Zone. The activities require minimal equipment and can be performed in the classroom, hallway or on the school playground.
Study: NCT03054857

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: After skin incision, the dexmedetomidine group received a loading dose of 0.5 mcg/kg of Dexmedetomidine in 20 minutes followed by a continuous IV infusion at 0.4 mcg/kg/hr until the end of operation.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The control group received a loading dose and continuous IV infusion of normal saline at the same volume and rate as in the dexmedetomidine group
Study: NCT02057471

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravenous ferric carboxymaltose
Description: 1 gram intravenous ferric carboxymaltose (FERINJECT) will be administered to all patients within the study
Study: NCT02482987

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dense polytetrafluoroethylene (dPTFE) membrane Cytoplast
Description: ridge preservation intervention using the dPTFE membrane device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: human amniotic-tissue derived membrane BioXclude
Description: ridge preservation intervention using the dPTFE membrane device

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ridge Preservation with overlay graft
Description: ridge preservation intervention with additional freeze dried bone allograft (FDBA) placed buccal to the socket

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ridge Preservation with overlay graft
Description: ridge preservation intervention with additional freeze dried bone allograft (FDBA) placed buccal to the socket

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ridge Preservation without overlay graft
Description: ridge preservation without overlay graft / traditional FDBA placement into the socket only

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ridge Preservation without overlay graft
Description: ridge preservation without overlay graft / traditional FDBA placement into the socket only
Study: NCT02389998

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo Suspension
Description: The study is divided into three phases: 1 one-week baseline assessment followed by 2 three-week study phases (phase A and phase B). Phase A will require subjects to take 1/4 teaspoon placebo suspension 2 times a day (morning and night), and a third dose if necessary. In phase B subjects will not take the placebo. After 3 weeks in initial phase (either Phase A or B), subjects will switch to the alternate phase and continue the study for another 3 weeks. Hyoscyamine is available as a rescue medication during Phase A and Phase B. Half of the subjects will be randomized to begin with Phase A and half will be randomized to begin with Phase B.

Intervention type: DRUG
Group type: OTHER
Intervention: Hyoscyamine
Description: While not an intervention of interest to our study, patients will have hyoscyamine available as a rescue medication throughout the study. This can be taken on a PRN basis for breakthrough pain a maximum of 4x daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyoscyamine
Description: While not an intervention of interest to our study, patients will have hyoscyamine available as a rescue medication throughout the study. This can be taken on a PRN basis for breakthrough pain a maximum of 4x daily.
Study: NCT00373867

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard physical therapy
Description: Treatment-based classification physical therapy

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Graded exercise
Description: Graded exercise increases an individual's tolerance to activity over time

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Graded exposure
Description: Graded exposure places the individual in fearful situations and gradually increases their exposure to such situations.
Study: NCT02428413

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ISO-Gard Mask
Description: to scavenge waste anesthetic gases from patients and provide supplemental oxygen

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard oxygen mask
Description: Provide supplemental oxygen
Study: NCT04496661

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation on M1 and Peripheral Electrical Stimulation
Description: Patients will be submitted to 10 treatment sessions, five days a week, for 30 minutes, paired to the same PES protocol. The participants will be positioned in ventral decubitus position. The direct current (2 mA) will be transferred through a neuro-stimulator (TransCranial Technologies, Hong Kong, China), with the use of electrodes and 4x4 cm sponges moistened with 0.9% saline solution. The anodic electrode will be placed on C3 to stimulate the left primary motor cortex according to the international 10-20 EEG system. The reference electrode will be positioned in the supra orbital contralateral region. For the PES, four self-adhesive electrodes with dimensions of 5 x 5 cm will be placed at the height between the T12 and S1 vertebrae in order to cover the entire lumbar area. A 20Hz frequency and pulse duration of 330ms will be provided by means of two channels from an electro-stimulator (Neurodyn, Ibramed).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation on DLPFC and Peripheral Electrical Stimulation
Description: Patients will be submitted to 10 treatment sessions, five days a week, for 30 minutes, paired to the same PES protocol. The direct current (2 mA) will be transferred through a neuro-stimulator (TransCranial Technologies, Hong Kong, China), with the use of electrodes and 4x4 cm sponges moistened with 0.9% saline solution. The anodic electrode will be placed on F3 to stimulate the left dorsolateral cortex according to the international 10-20 EEG system. The reference electrode will be positioned in the supra orbital contralateral region. For the PES, four self-adhesive electrodes with dimensions of 5 x 5 cm will be placed at the height between the T12 and S1 vertebrae in order to cover the entire lumbar area. A 20Hz frequency and pulse duration of 330ms will be provided by means of two channels from an electro-stimulator (Neurodyn, Ibramed).

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham tDCS and PES
Description: For sham tDCS and PES stimulation, patients will be submitted to 10 treatment sessions, five days a week, for 30 minutes. The anodic electrode will be positioned on the left primary motor cortex, but the current will be turned off automatically after 30 seconds. The reference electrode will be positioned in the supra orbital contralateral region. For sham PES stimulations, four self-adhesive electrodes with dimensions of 5 x 5 cm will be placed at the height between the T12 and S1 vertebrae in order to cover the entire lumbar area. A 20Hz frequency and pulse duration of 330ms will be provided by means of two channels from an electro-stimulator (Neurodyn, Ibramed), but the current will be turned off automatically after 30 seconds.
Study: NCT02925741

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Silk-Like Linens
Description: Synthetic moisture-wicking fabric
Study: NCT01248871

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: procedure:sevoflurane-remifentanil/sufentanil
Description: Active Comparator
Study: NCT00379626

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cognitive and hormone treatment
Description: cognitive and hormone (Leuprorelin) treatment
Study: NCT03034720

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Care
Description: Intervention subjects will receive treatment from an MSW-trained care manager over the course of 6-months after randomization. Intervention team members will work collaboratively with primary care providers to link physical and mental health care longitudinally through outpatient follow-up and community rehabilitation. Intervention subjects and their families and collaborative team members will share information and deliberate treatment decisions with each other in order to develop an individually tailored treatment plan. Stepped, higher intensity care will be available for intervention subjects with recurrent symptoms. Stepped up care will include CBT booster sessions targeting post-concussive and related symptom comorbidity as well as psychopharmacologic assessment and treatment.
Study: NCT03644199

Intervention type: OTHER
Group type: OTHER
Intervention: Oral Glucose Tolerance Test (OGTT) assessment arm
Description: Hormonal and motility responses to a standard OGTT evaluation arm

Intervention type: OTHER
Group type: OTHER
Intervention: Mixed meal test evaluation test arm
Description: Evaluate the hormonal and motility responses to a standard mixed meal test through the day
Study: NCT00746993

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structured contraceptive counseling
Description: Uniform set of visual information about contraception which a counselor will read out loud with each participant and answer questions.
Study: NCT02424968

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Total Nodal Irradiation
Description: Undergo TLI
Study: NCT05028465

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic Papillectomy
Description: A snare devicewas inserted via the working channel, and the endoscopist adjusted the snare to securely grasp the lesion, which was then excised by using standard electrocautery.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endobiliary Radiofrequency Ablation
Description: The RFA catheter was then placed under fluoroscopic guidance across the distal common bile duct. An ERBE VIO200D generator (ERBE Elktromedizin, Tubingen, Germany) was connected for RFA at 10 W for 90 seconds.
Study: NCT00691691

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiation Therapy
Description: Radiation Dose: 48 Gy in 4 fractions in 2 weeks. A minimum of 48 hours should separate each treatment (e.g. every Tuesday and Friday). The dose is prescribed to the marginal isodose (80-90%) that encompasses the entire target lesion (GTV). Treatment will be delivered using a linear accelerator. For verification of the accuracy of these external skin fiducial markers, 10 patients will also have implanted internal gold coil markers. The implantable gold coil markers will be implanted into the liver in the proximity of the target lesions via a percutaneous transhepatic route under fluoroscopy guidance.
Study: NCT04377191

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exergame
Description: Microsoft Xbox 360 Kinect The exercises were advanced from simple to complex. The program started with exercises in a sitting position. In the next stage, the games requiring weight transfer and use of upper limbs in standing position were continued. The program ended with games that require more complex movements such as lunge and mini squats.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exergame
Description: ALDA In the training, games that could be controlled by balance swing, trunk movements and weight transfer in sitting or standing position were used.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercise
Description: Standard Exercise Program The program included warm-up, main exercise and cooling. Warm-up and cooling included neck, trunk, upper-lower extremity range of movement (ROM) exercises and stretching exercises. Main exercise included postural alignment, strengthening for trunk and lower extremity, balance and walking exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: Standard Exercise Program The program included warm-up, main exercise and cooling. Warm-up and cooling included neck, trunk, upper-lower extremity range of movement (ROM) exercises and stretching exercises. Main exercise included postural alignment, strengthening for trunk and lower extremity, balance and walking exercises.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: Standard Exercise Program The program included warm-up, main exercise and cooling. Warm-up and cooling included neck, trunk, upper-lower extremity range of movement (ROM) exercises and stretching exercises. Main exercise included postural alignment, strengthening for trunk and lower extremity, balance and walking exercises.
Study: NCT01976507

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dabigatran etexilate mesylate
Description: Immediately following the ablation procedure (4-6 hours after sheath pull and vascular hemostasis), dabigatran etexilate 150mg bid, or 75mg twice daily based on creatinine clearance in the Use in Specified Populations (USPI), will be administered for a minimum of 3 months post RF ablation.
Study: NCT02858115

Intervention type: OTHER
Intervention: Fluid challenge
Description: 100 ml of crystalloid was infused over 1-min
Study: NCT01248871

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: volatile agent only during reperfusion
Description: Active Comparator

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: propofol-remifentanil/sufentanil
Description: Active Comparator
Study: NCT02858115

Intervention type: OTHER
Intervention: Trans-oesophageal echography
Description: an echocardiographic assessment at 1-min,