Study: NCT01487512

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment A: Hydromorphone 8 mg
Description: type= exact number, unit= mg, number= 8, form= tablet, route= oral use. One tablet of Hydromorphone 8 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment A: Hydromorphone 8 mg
Description: type= exact number, unit= mg, number= 8, form= tablet, route= oral use. One tablet of Hydromorphone 8 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment A: Hydromorphone 8 mg
Description: type= exact number, unit= mg, number= 8, form= tablet, route= oral use. One tablet of Hydromorphone 8 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment A: Hydromorphone 8 mg
Description: type= exact number, unit= mg, number= 8, form= tablet, route= oral use. One tablet of Hydromorphone 8 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment B: Hydromorphone 16 mg
Description: type= exact number, unit= mg, number= 16, form= tablet, route= oral use. One tablet of Hydromorphone 16 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment B: Hydromorphone 16 mg
Description: type= exact number, unit= mg, number= 16, form= tablet, route= oral use. One tablet of Hydromorphone 16 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment B: Hydromorphone 16 mg
Description: type= exact number, unit= mg, number= 16, form= tablet, route= oral use. One tablet of Hydromorphone 16 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment B: Hydromorphone 16 mg
Description: type= exact number, unit= mg, number= 16, form= tablet, route= oral use. One tablet of Hydromorphone 16 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment C: Hydromorphone 32 mg
Description: type= exact number, unit= mg, number= 32, form= tablet, route= oral use. One tablet of Hydromorphone 32 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment C: Hydromorphone 32 mg
Description: type= exact number, unit= mg, number= 32, form= tablet, route= oral use. One tablet of Hydromorphone 32 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment C: Hydromorphone 32 mg
Description: type= exact number, unit= mg, number= 32, form= tablet, route= oral use. One tablet of Hydromorphone 32 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment C: Hydromorphone 32 mg
Description: type= exact number, unit= mg, number= 32, form= tablet, route= oral use. One tablet of Hydromorphone 32 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment D: Hydromorphone 64 mg
Description: type= exact number, unit= mg, number= 64, form= tablet, route= oral use. One tablet of Hydromorphone 64 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment D: Hydromorphone 64 mg
Description: type= exact number, unit= mg, number= 64, form= tablet, route= oral use. One tablet of Hydromorphone 64 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment D: Hydromorphone 64 mg
Description: type= exact number, unit= mg, number= 64, form= tablet, route= oral use. One tablet of Hydromorphone 64 mg in each of 4 treatment sequences.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment D: Hydromorphone 64 mg
Description: type= exact number, unit= mg, number= 64, form= tablet, route= oral use. One tablet of Hydromorphone 64 mg in each of 4 treatment sequences.