Study: NCT02632110

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALA
Description: 20% ALA applied to face prior to light treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALA
Description: 20% ALA applied to face prior to light treatment

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALA
Description: 20% ALA applied to face prior to light treatment

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Topical Solution Vehicle
Description: Levulan Kerastick containing vehicle ingredients only. Vehicle solution applied to face prior to light treatment

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Topical Solution Vehicle
Description: Levulan Kerastick containing vehicle ingredients only. Vehicle solution applied to face prior to light treatment

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 10 mW
Description: 10 J/cm2 blue light delivered at 10 mW/cm2 for 16 minutes 40 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 10 mW
Description: 10 J/cm2 blue light delivered at 10 mW/cm2 for 16 minutes 40 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 10 mW
Description: 10 J/cm2 blue light delivered at 10 mW/cm2 for 16 minutes 40 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 10 mW
Description: 10 J/cm2 blue light delivered at 10 mW/cm2 for 16 minutes 40 seconds

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: IBL 10 mW
Description: 10 J/cm2 blue light delivered at 10 mW/cm2 for 16 minutes 40 seconds

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: IBL 10 mW
Description: 10 J/cm2 blue light delivered at 10 mW/cm2 for 16 minutes 40 seconds

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microneedle lesion preparation
Description: Microneedling of all visible/palpable AK lesions prior to solution application.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microneedle lesion preparation
Description: Microneedling of all visible/palpable AK lesions prior to solution application.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microneedle lesion preparation
Description: Microneedling of all visible/palpable AK lesions prior to solution application.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microneedle lesion preparation
Description: Microneedling of all visible/palpable AK lesions prior to solution application.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Microneedle lesion preparation
Description: Microneedling of all visible/palpable AK lesions prior to solution application.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 20 mW
Description: 10 J/cm2 blue light delivered at 20 mW/cm2 for 8 minutes 20 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 20 mW
Description: 10 J/cm2 blue light delivered at 20 mW/cm2 for 8 minutes 20 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 20 mW
Description: 10 J/cm2 blue light delivered at 20 mW/cm2 for 8 minutes 20 seconds

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IBL 20 mW
Description: 10 J/cm2 blue light delivered at 20 mW/cm2 for 8 minutes 20 seconds