Study: NCT04183686

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (SAD)
Description: Single dose of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (SAD)
Description: Single dose of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (SAD)
Description: Single dose of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (SAD)
Description: Single dose of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (SAD)
Description: Single dose of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (SAD)
Description: Single dose of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (MAD)
Description: Multiple doses of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (MAD)
Description: Multiple doses of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (MAD)
Description: Multiple doses of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACT-1014-6470 (MAD)
Description: Multiple doses of ACT-1014-6470; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (SAD)
Description: Single dose of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (SAD)
Description: Single dose of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (SAD)
Description: Single dose of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (SAD)
Description: Single dose of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (SAD)
Description: Single dose of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (SAD)
Description: Single dose of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (MAD)
Description: Multiple doses of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (MAD)
Description: Multiple doses of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (MAD)
Description: Multiple doses of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (MAD)
Description: Multiple doses of matching placebo; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 14C-ACT-1014-6470 microtracer
Description: Single dose of 14C-ACT-1014-6470 microtracer; soft capsules for oral use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 14C-ACT-1014-6470 microtracer placebo
Description: Single dose of matching placebo; soft capsules for oral use.