TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT01514032

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extracorporal shockwave lithotripsy
Description: Extracorporal shockwave lithotripsy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Retrograde intrarenal surgery
Description: Retrograde intrarenal surgery
Study: NCT01954693

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 5mg daily administered for 6 months as two oral 2.5 mg tablets once daily.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus (RAD001)
Description: 5mg daily administered for 6 months as two oral 2.5 mg tablets once daily
Study: NCT02415712

Intervention type: DRUG
Intervention: Fomepizole
Description: The first dose of fomepizole is administered at a dose of 15 mg/kg, followed by the second to fifth doses administered at a dose of 10 mg/kg. The sixth and subsequent doses are administered at a dose of 15 mg/kg. The interval of the intravenous doses is 12 hours with one administration lasting more than 30 minutes.
Study: NCT02009644

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Subjects who receive the Treovance stent-graft
Description: Eligible subjects will be implanted with the Treovance Stent-Graft
Study: NCT02440815

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Problem Solving Therapy
Description: Problem Solving Therapy (PST) is a brief evidence based psychotherapy that is commonly utilized for treatment of LLD. The problem solving therapy includes 12 weekly in person 50 minute sessions.
Study: NCT00670592

Intervention type: DRUG
Group type: OTHER
Intervention: HCD122
Study: NCT01641614

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mitral valve replacement
Description: Mitral valve replacement (MVR) was performed using a metallic or bioprostheses substitution by interrupted suture. For the beating heart the prostheses was functionally tested before removal of the retrograde perfusion catheter and for the arrested heart the prosthesis was artificially tested by pumping saline into the left ventricle. The tricuspid valve repair was done following De Vegas' technique in both groups

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mitral valve replacement
Description: Mitral valve replacement (MVR) was performed using a metallic or bioprostheses substitution by interrupted suture. For the beating heart the prostheses was functionally tested before removal of the retrograde perfusion catheter and for the arrested heart the prosthesis was artificially tested by pumping saline into the left ventricle. The tricuspid valve repair was done following De Vegas' technique in both groups
Study: NCT01345331

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Real stimulation VS Sham
Description: Ear stimulation at specific points should work by stimulating a nerve called the vagus nerve. Previous research has shown that stimulating this nerve can help patients feel less pain. During any testing session, participants may receive either the real ear stimulation or a sham (placebo) treatment. The sham treatment will use the same equipment as the real treatment, but will not deliver any real stimulation to the ear. We use placebo/sham procedures in research to make sure that the study results are related to the study procedure, and not to other reasons.

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Real stimulation VS Sham
Description: Ear stimulation at specific points should work by stimulating a nerve called the vagus nerve. Previous research has shown that stimulating this nerve can help patients feel less pain. During any testing session, participants may receive either the real ear stimulation or a sham (placebo) treatment. The sham treatment will use the same equipment as the real treatment, but will not deliver any real stimulation to the ear. We use placebo/sham procedures in research to make sure that the study results are related to the study procedure, and not to other reasons.
Study: NCT04934761

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fluid challenge strategy
Description: Patients received 2ml/kg of succinylateol gelatin within 10 min for fluid shock therapy after grouping, taking SVV as the management target. If SVV\< 13% after shock therapy, the shock therapy was stopped and the infusion was maintained with 4ml/kg/h of crystal solution. If SVV ≥ 13% and ΔSV \<10%, the individual would be excluded from the experiment. If SVV ≥ 13% but ΔSV≥10%, 2ml/kg of succinylateol gelatin was given again within 10 min for liquid shock therapy until SVV\<13%, and 4ml/kg/h of crystal solution was maintained after reaching the target. If SVV≥ 13% after two shock treatments, they were excluded from the experiment. We excluded patients whose intraoperative bleeding ≥400ml and operative time ≥5 hours from the group.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: conventional strategy
Description: 4ml/kg/h of crystal solution was maintained. We excluded patients whose intraoperative bleeding ≥400ml and operative time ≥5 hours from the group.
Study: NCT00057473

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: carboplatin + irinotecan
Description: Solution, IV, Carbopaltin AUC 4 mg/ml.min every 21 days; irinotecan 12 mg/m2/day x 10 days , Minimum of two cycles of chemotherapy projected to be up to 6.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: irinotecan
Description: Solution, IV, irinotecan 12 mg/m2/day x 10 days, minimum of two cycles of chemotherapy projected to be up to 6.
Study: NCT02085499

Intervention type: OTHER
Group type: OTHER
Intervention: non-synchronized NIMV
Description: During the study each infant will undergo a 2-hour period of NIMV at a frequency of 30 cycles per minute.~NIMV will be provided by a time cycled, pressure limited neonatal ventilator (Puritan Bennett 840, Covidien, Boulder, CO).

Intervention type: OTHER
Group type: OTHER
Intervention: non-synchronized NIMV
Description: During the study each infant will undergo a 2-hour period of NIMV at a frequency of 30 cycles per minute.~NIMV will be provided by a time cycled, pressure limited neonatal ventilator (Puritan Bennett 840, Covidien, Boulder, CO).

Intervention type: OTHER
Group type: OTHER
Intervention: Synchronized NIMV
Description: During the study each infant will undergo a 2-hour period of S-NIMV at a frequency of 30 cycles per minute.~S-NIMV will be provided by a time cycled, pressure limited neonatal ventilator, with leak compensation capacity and nasal flow triggered ventilation (Puritan Bennett 840, Covidien, Boulder, CO). Synchronization will be achieved by the leak compensation software and the internal sensor of the ventilator.

Intervention type: OTHER
Group type: OTHER
Intervention: Synchronized NIMV
Description: During the study each infant will undergo a 2-hour period of S-NIMV at a frequency of 30 cycles per minute.~S-NIMV will be provided by a time cycled, pressure limited neonatal ventilator, with leak compensation capacity and nasal flow triggered ventilation (Puritan Bennett 840, Covidien, Boulder, CO). Synchronization will be achieved by the leak compensation software and the internal sensor of the ventilator.
Study: NCT05359978

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: To with significance activities
Description: activities with purpose with people who are diagnosed of dementia 2 days at week during 30 minutes

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: To with significance activities
Description: activities with purpose with people who are diagnosed of dementia 2 days at week during 30 minutes
Study: NCT00556660

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [123I] AV-151
Description: To assess the dynamic uptake and washout of 123-I AV151, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT) in similarly aged healthy controls and Alzheimer's (AD) subjects
Study: NCT05991856

Intervention type: PROCEDURE
Intervention: radiofrequency ablation
Description: The subjects is placed in a prone or lateral position under local anesthesia, and the electrodes are placed in the adrenal nodules under ultrasound guidance. A rapidly alternating radiofrequency current (300-500khz) generated around the electrode propagates through the adrenal nodules, causing resistance heating (Joule effect) and inducing cell death through coagulation necrosis. The choice of ablation time and frequency depends on the size, shape and location of the nodules within the adrenal gland.

Intervention type: PROCEDURE
Intervention: laparoscopic adrenalectomy
Description: The subjects was placed in a lateral position under general anesthesia. Using harmonic scalpel carefully separates the adrenal vessels and lates them. The adipose tissue around the adrenal gland is dissected carefully, the surrounding tissue is bluntly separated, and the adrenal gland is fully exposed and dissected. After adrenalectomy was completed, hemostasis was rechecked and specimens were removed.

Intervention type: DRUG
Intervention: Hypotensive Drugs
Description: All subjects in the study selected appropriate antihypertensive drugs based on factors such as blood pressure level.

Intervention type: DRUG
Intervention: Hypotensive Drugs
Description: All subjects in the study selected appropriate antihypertensive drugs based on factors such as blood pressure level.
Study: NCT03872804

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autologous punch mini grafts:
Description: Under local anesthesia, multiple 1mm holes will be made in the depigmented treatment area using 1mm punch graft instrument inserted to a depth of 2-4 mm to remove a small column of depigmented skin that is to be discarded. The punches will be situated at or very close to the border of the lesion to avoid leaving an achromic fissure and will be separated by 5-8 mm distance from each other.~On the donor area mostly is the gluteal area, punches will be harvested using the same sized punches very close to each other so that maximum number of grafts can be taken from a small area.~Then the harvested-punch minigrafts will be inserted into the recipient chambers, pressed firmly by saline soaked gauge for hemostasis and secured by sterile strips or a compression bandage if applicable.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transverse needling
Description: Needling will be done for selected treatment patch using a 30 G disposable insulin syringe, going from the pigmented margins of the lesion into the vitiliginous patch, Position of the needle will be kept close to the dermoepidermal junction and movement will be from normal skin towards the lesion. Needle pricks may lead to oozing of a small drop of blood which will be managed by physical pressure. No dressings will be needed. The procedure will be repeated for selected lesions weekly for a duration of 3 months.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Punch minigrafts followed by transverse needling
Description: In a third lesion, punch minigrafts will be done as mentioned in line 1 and will be left to stabilize for 3 months then transverse needling will be done weekly for the margins of the lesion as well as the areas of the punch grafts toward the vitiliginous area.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral pulse steroid with narrow band
Description: * A fourth lesion will be chosen as a control lesion, to which no surgical treatment will ba attempted.~* All lesions will receive NB-UVB therapy according to standard protocol twice weekly and the patients will continue on the oral mini pulse dexamethasone at 2.5 mg dose for two consecutive days weekly all through the study period
Study: NCT00041093

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Given IV
Study: NCT01608412

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tacrolimus
Description: TACROLIMUS (C0 = 5-10 ng/mL) + MPS 1440 mg + Pred

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Everolimus
Description: Everolimus (C0 = 6-10 ng/mL) + MPS 1440 mg + Pred
Study: NCT03826927

Intervention type: OTHER
Intervention: treatment with NOACs or VKAs
Description: treatment with NOACs or VKAs initiated or continued for prevention of ischemic events
Study: NCT01226238

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online self-help
Description: Provision of online self-help
Study: NCT00584194

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TSI-GSD 200 RVF Vaccine
Description: Part A: Inactivated, Dried (TSI-GSD 200) RVF vaccine will be given as three 1.0-ml subcutaneous primary series injections, with doses on day 0, once on days 7-14, once on days 28-42 (the third dose will be given at least 21 days after the second dose).Part B: Subcutaneous 1.0-ml booster doses (maximum of four boosters over 12 months) will be given if the volunteer fails to respond to the primary series with a PRNT80 ≥ 1:40 or annually if titer wanes to \< 1:40.
Study: NCT03011333

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: HTX-011 (bupivacaine/meloxicam) via nerve block or instillation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: HTX-011 (bupivacaine/meloxicam) via nerve block or instillation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: HTX-011 (bupivacaine/meloxicam) via nerve block or instillation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: HTX-011 (bupivacaine/meloxicam) via nerve block or instillation.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTX-011
Description: HTX-011 (bupivacaine/meloxicam) via nerve block or instillation.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl without epinephrine
Description: Bupivacaine HCl without epinephrine, 50 mg via nerve block.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline Placebo
Description: Saline placebo via nerve block.
Study: NCT03178487

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Upadacitinib
Description: Tablet

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Upadacitinib
Description: Tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Tablet
Study: NCT03315923

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Patients will receive 1 g of rituximab (two vials of Zytux 500 mg/50 ml) in 500 cc normal saline serum through intravenous infusion as one treatment cycle. This cycle will be repeated every 6 months. Along with rituximab, patients will receive 100 mg of methylprednisolone, 10 mg of chlorpheniramine, and 500 mg of acetaminophen. Before each cycle, patients will be evaluated regarding complete blood count (CBC)-diff, blood urea nitrogen (BUN), Cr, and liver function tests.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glatiramer Acetate
Description: Patients will receive 40 mg of glatiramer acetate three times per week through subcutaneous injection. Patients will undergo electrocardiography before starting the treatment to find any abnormal finding. Also, lab tests will be checked for them prior to the treatment, including CBC-diff, BUN, Cr, and liver function tests.
Study: NCT04093531

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ustekinumab
Description: Up to 15 subjects will receive an infusion loading dose of 6 mg/kg of ustekinumab at baseline, and 90 mg of ustekinumab subcutaneously at week 4, week 12 and week 20. Subjects will be followed for 24 weeks.
Study: NCT00634491

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: sodium bicarbonate
Description: 150 meq/l Sodium bicarbonate 3cc/kg/hr before and 1cc/kg/hr after angiography

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetazolamide
Description: Acetazolamide 250 mg+ 1 cc/kg/hr normal salin before and after angiography

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: normal salin
Description: 1 cc/kg/hr 6 hour before and after angiography
Study: NCT02070042

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omega 3 Fatty Acid
Description: Trunature® Triple Strength Omega-3, given twice a day. Each capsule contains 647 mg Eicosapentaenoic Acid (EPA) and 253 mg Docosahexaenoic Acid (DHA).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsules (olive oil) twice a day
Study: NCT01262846

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Fluzone®
Description: Fluzone® Standard dose in a blinded manner as single-0.5mL injection intramuscularly into one of the subject's deltoid muscles.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Fluzone®
Description: Fluzone® High dose or Standard dose in a blinded manner as single-0.5mL injection intramuscularly into one of the subject's deltoid muscles.
Study: NCT01285908

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous Norepinephrine Infusion

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Intravenous Norepinephrine Infusion
Study: NCT02559687

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: pembrolizumab
Description: IV Q3W
Study: NCT02163473

Intervention type: PROCEDURE
Intervention: Septic patients
Description: The investigators will draw two sets of blood samples. One at baseline, 10 mL, and another, 24 hours later, 10 mL, for a total of 20 mL.

Intervention type: PROCEDURE
Intervention: Healthy Control
Description: The investigators will draw 10 mL, once, during baseline for a total of 10 mL among the healthy control group.
Study: NCT03406221

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Information Communication Technology Continuum of Care Service
Description: Mobile phones were made available to community health workers in the intervention arms that integrated a comprehensive set of functions to assist them in their duties, including registration and tracking of beneficiaries, automated scheduling of home visits, provision of health information through videos, guided protocols for conducting home visits through checklists, a feature to track child immunizations, and supervisory tools.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Condition
Description: Standard of care
Study: NCT01184482

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cetuximab and lapatinib
Description: Cetuximab: 400 mg/m2 on Day 1 then 250 mg/m2 weekly~Lapatinib: Start once daily on Day 1. Dose escalating cohorts:~1. 750 mg (3 tabs)~2. 1000 mg (4 tabs)~3. 1250 mg (5 tabs)
Study: NCT01978093

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Hib-MenCY-TT (MenHibrix®)
Description: 4 doses administered intramuscularly (IM) in the right upper anterolateral thigh at Day 0, Month 2, Month 4 and Month 10-13 in the HibCY Group.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pediarix®
Description: 3 doses administered IM in the left upper anterolateral thigh at Day 0, Month 2 and Month 4. 2 doses administered IM in the left upper anterolateral thigh at Day 0 and Month 2 and 1 dose administered IM in the right upper anterolateral thigh at Month 4 in the PedHIB Group.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pediarix®
Description: 3 doses administered IM in the left upper anterolateral thigh at Day 0, Month 2 and Month 4. 2 doses administered IM in the left upper anterolateral thigh at Day 0 and Month 2 and 1 dose administered IM in the right upper anterolateral thigh at Month 4 in the PedHIB Group.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rotarix®
Description: 2 doses administered orally at Day 0 and Month 2 each in the HibCY Group and PedHIB Group.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Rotarix®
Description: 2 doses administered orally at Day 0 and Month 2 each in the HibCY Group and PedHIB Group.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Prevnar 13®
Description: 4 doses administered IM in the left lower anterolateral thigh at Day 0, Month 2, Month 4 and Month 10-13 each in the HibCY Group and PedHIB Group.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevnar 13®
Description: 4 doses administered IM in the left lower anterolateral thigh at Day 0, Month 2, Month 4 and Month 10-13 each in the HibCY Group and PedHIB Group.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: PedvaxHIB®
Description: 3 doses administered IM in the right upper anterolateral thigh at Day 0, Month 2 and Month 10-13 in the PedHIB Group.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Havrix®
Description: 2 doses administered IM in the left upper anterolateral thigh at Month 10-13 and Month 16-19 each in the HibCY Group and PedHIB Group.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Havrix®
Description: 2 doses administered IM in the left upper anterolateral thigh at Month 10-13 and Month 16-19 each in the HibCY Group and PedHIB Group.
Study: NCT02956668

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blindsight Training associated to tDCS
Description: The patient undergo visual rehabilitation while his brain is electrically stimulated with tDCS.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blindsight Training alone
Description: The patient undergo visual rehabilitation
Study: NCT02570633

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Extract of ginger
Description: Migraine patients (both genders) will receive capsules of 200 mg of ginger extract (5% gingerols) to be taken three times a day for 12 weeks.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Cellulose
Description: Migraine patients (both genders) will receive capsules of 200 mg of placebo (cellulose) to be taken three times a day for 12 weeks.
Study: NCT01239160

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Flexitouch System
Description: A segmental, programmable, gradient pneumatic compression device. It consists of a controller and garment set. The garments are constructed of nylon and have 27-32 chambers, depending upon garment size. The pressure setting is variable between normal and increased. The device is intended to be used for 60 minutes per day

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hydroven FPR
Description: The FH is an intermittent sequential external pneumatic compression system. The garment contains 3 compression chambers. The pressure range of the compressor device is 30-100 mmHg. It is intended to be used for 60 minutes per day.
Study: NCT00000511

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: mineral supplements

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Trial 1: fatty acids, omega-3; Trial 2: Mineral supplements

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: dietary supplements
Study: NCT01826682

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy program+medical treatment
Description: Patients included in this group are going to receive physiotherapy during their hospital stay 45 minutes every day. The physical training is based on respiratory exercises, the use of a flutter (positive expiratory pressure), pedaling and theraband exercises.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Medical treatment
Description: Standard medical treatment without physiotherapy.