Study: NCT01463514

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Right heart catheterization
Description: Oxygenation and hemodynamic parameters will be assessed during RHC according to standard procedures. All measurements will be noted as usual for PH assessment including: at rest breathing room air, during an oxygen challenge, under vasodilator testing with NO and/or during exercise. Room air, supplemental oxygen and NO will be applied over common breathing mask while patient is in a supine position. Oxygen will be taken as usual from the common adjustable hospital wall access, NO will be taken according to usual clinical practice during RHC from a gas cylinder connected to a reservoir, where adequate ppm concentration can be regulated. A dose of 40 ppm NO will be used according to common practise. Oxygen delivery to maintain the peripheral oxygen saturation between 88% and 90% will be adjusted over a 3 minute period of time.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Right heart catheterization
Description: Oxygenation and hemodynamic parameters will be assessed during RHC according to standard procedures. All measurements will be noted as usual for PH assessment including: at rest breathing room air, during an oxygen challenge, under vasodilator testing with NO and/or during exercise. Room air, supplemental oxygen and NO will be applied over common breathing mask while patient is in a supine position. Oxygen will be taken as usual from the common adjustable hospital wall access, NO will be taken according to usual clinical practice during RHC from a gas cylinder connected to a reservoir, where adequate ppm concentration can be regulated. A dose of 40 ppm NO will be used according to common practise. Oxygen delivery to maintain the peripheral oxygen saturation between 88% and 90% will be adjusted over a 3 minute period of time.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Right heart catheterization
Description: Oxygenation and hemodynamic parameters will be assessed during RHC according to standard procedures. All measurements will be noted as usual for PH assessment including: at rest breathing room air, during an oxygen challenge, under vasodilator testing with NO and/or during exercise. Room air, supplemental oxygen and NO will be applied over common breathing mask while patient is in a supine position. Oxygen will be taken as usual from the common adjustable hospital wall access, NO will be taken according to usual clinical practice during RHC from a gas cylinder connected to a reservoir, where adequate ppm concentration can be regulated. A dose of 40 ppm NO will be used according to common practise. Oxygen delivery to maintain the peripheral oxygen saturation between 88% and 90% will be adjusted over a 3 minute period of time.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Right heart catheterization
Description: Oxygenation and hemodynamic parameters will be assessed during RHC according to standard procedures. All measurements will be noted as usual for PH assessment including: at rest breathing room air, during an oxygen challenge, under vasodilator testing with NO and/or during exercise. Room air, supplemental oxygen and NO will be applied over common breathing mask while patient is in a supine position. Oxygen will be taken as usual from the common adjustable hospital wall access, NO will be taken according to usual clinical practice during RHC from a gas cylinder connected to a reservoir, where adequate ppm concentration can be regulated. A dose of 40 ppm NO will be used according to common practise. Oxygen delivery to maintain the peripheral oxygen saturation between 88% and 90% will be adjusted over a 3 minute period of time.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Near-infrared spectroscopy
Description: For study purpose, patients will have additional non-invasive NIRS assessment. The measurement will take place during right heart catheterization.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Near-infrared spectroscopy
Description: For study purpose, patients will have additional non-invasive NIRS assessment. The measurement will take place during right heart catheterization.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Near-infrared spectroscopy
Description: For study purpose, patients will have additional non-invasive NIRS assessment. The measurement will take place during right heart catheterization.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Near-infrared spectroscopy
Description: For study purpose, patients will have additional non-invasive NIRS assessment. The measurement will take place during right heart catheterization.