Study: NCT01878617

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Craniospinal Irradiation with boost to the primary tumor site
Description: All participants will undergo craniospinal irradiation (CSI) with boost to the primary tumor site. The dose given is based on the molecular and risk group as noted in the arm descriptions. The type of radiation used includes conformal radiation therapy (photons) or intensity modulated radiation therapy (IMRT) or proton beam therapy.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Route of Administration (ROA): Intravenously (IV)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: ROA: IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: ROA: IV