Study: NCT01208207

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - etoricoxib 60 mg
Description: etoricoxib 60 mg oral tablet once daily for 6 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - etoricoxib 60 mg
Description: etoricoxib 60 mg oral tablet once daily for 6 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - etoricoxib 90 mg
Description: etoricoxib 90 mg oral tablet once daily for 6 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Part I- naproxen 1000 mg
Description: naproxen 500 mg oral tablet twice daily for 6 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - Placebo to naproxen 500 mg
Description: Placebo to naproxen 500 mg oral tablet twice daily for 6 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - Placebo to naproxen 500 mg
Description: Placebo to naproxen 500 mg oral tablet twice daily for 6 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - Placebo to naproxen 500 mg
Description: Placebo to naproxen 500 mg oral tablet twice daily for 6 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- etoricoxib 60 mg
Description: etoricoxib 60 mg oral tablet once daily for 20 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- etoricoxib 90 mg
Description: etoricoxib 90 mg oral tablet once daily for 20 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- etoricoxib 90 mg
Description: etoricoxib 90 mg oral tablet once daily for 20 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Part II- naproxen 1000 mg
Description: naproxen 500 mg oral tablet twice daily for 20 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - Placebo to etoricoxib 60 mg
Description: Placebo to etoricoxib 60 mg oral tablet once daily for 6 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Part I - Placebo to etoricoxib 60 mg
Description: Placebo to etoricoxib 60 mg oral tablet once daily for 6 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - Placebo to etoricoxib 90 mg
Description: Placebo to etoricoxib 90 mg oral tablet once daily for 6 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part I - Placebo to etoricoxib 90 mg
Description: Placebo to etoricoxib 90 mg oral tablet once daily for 6 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Part I - Placebo to etoricoxib 90 mg
Description: Placebo to etoricoxib 90 mg oral tablet once daily for 6 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- Placebo to etoricoxib 60 mg
Description: Placebo to etoricoxib 60 mg oral tablet once daily for 20 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- Placebo to etoricoxib 60 mg
Description: Placebo to etoricoxib 60 mg oral tablet once daily for 20 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Part II- Placebo to etoricoxib 60 mg
Description: Placebo to etoricoxib 60 mg oral tablet once daily for 20 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II - Placebo to etoricoxib 90 mg
Description: Placebo to etoricoxib 90 mg oral tablet once daily for 20 weeks.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Part II - Placebo to etoricoxib 90 mg
Description: Placebo to etoricoxib 90 mg oral tablet once daily for 20 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- Placebo to naproxen 500 mg
Description: Placebo to naproxen 500 mg orally twice daily for 20 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- Placebo to naproxen 500 mg
Description: Placebo to naproxen 500 mg orally twice daily for 20 weeks.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Part II- Placebo to naproxen 500 mg
Description: Placebo to naproxen 500 mg orally twice daily for 20 weeks.