Study: NCT03522207

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: polysomnography
Description: BASELINE PSG Patient has to sleep over at the hospital (sleep lab). The technician will place several sensors on your scalp, temples, chest and legs to record all the data needed for your evaluation. You will be monitored throughout the duration of the test (approximately 6 hours). Brain waves, eye movements, chin muscle tone, breathing patterns, snoring, heart rate, blood pressure, blood oxygen level, body position and muscle activity will be recorded.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: polysomnography
Description: BASELINE PSG Patient has to sleep over at the hospital (sleep lab). The technician will place several sensors on your scalp, temples, chest and legs to record all the data needed for your evaluation. You will be monitored throughout the duration of the test (approximately 6 hours). Brain waves, eye movements, chin muscle tone, breathing patterns, snoring, heart rate, blood pressure, blood oxygen level, body position and muscle activity will be recorded.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trazodone
Description: 100 mg trazodone or placebo given once 30 minutes prior to 2nd PSG

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebos
Description: placebo per os 30 minutes prior to 2nd PSG

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: polysomnography
Description: 2nd psg, done 1 week after baseline. Patient has to sleep over at the hospital (sleep lab). The technician will place several sensors on your scalp, temples, chest and legs to record all the data needed for your evaluation. You will be monitored throughout the duration of the test (approximately 6 hours). Brain waves, eye movements, chin muscle tone, breathing patterns, snoring, heart rate, blood pressure, blood oxygen level, body position and muscle activity will be recorded.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: polysomnography
Description: 2nd psg, done 1 week after baseline. Patient has to sleep over at the hospital (sleep lab). The technician will place several sensors on your scalp, temples, chest and legs to record all the data needed for your evaluation. You will be monitored throughout the duration of the test (approximately 6 hours). Brain waves, eye movements, chin muscle tone, breathing patterns, snoring, heart rate, blood pressure, blood oxygen level, body position and muscle activity will be recorded.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trazodone
Description: 100 mg trazodone per os 30 minutes prior to 3rd PSG

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebos
Description: 100 mg placebo per os 30 minutes prior to 3rd PSG

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: polysomnography
Description: 3rd PSG, done 2 weeks after baseline. Patient has to sleep over at the hospital (sleep lab). The technician will place several sensors on your scalp, temples, chest and legs to record all the data needed for your evaluation. You will be monitored throughout the duration of the test (approximately 6 hours). Brain waves, eye movements, chin muscle tone, breathing patterns, snoring, heart rate, blood pressure, blood oxygen level, body position and muscle activity will be recorded.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: polysomnography
Description: 3rd PSG, done 2 weeks after baseline. Patient has to sleep over at the hospital (sleep lab). The technician will place several sensors on your scalp, temples, chest and legs to record all the data needed for your evaluation. You will be monitored throughout the duration of the test (approximately 6 hours). Brain waves, eye movements, chin muscle tone, breathing patterns, snoring, heart rate, blood pressure, blood oxygen level, body position and muscle activity will be recorded.