Study: NCT02154880

Intervention type: PROCEDURE
Intervention: PFT
Description: Lung function endpoints of FVC, FEV1, FEV1/FVC, and FEF25-75% will be measured with the flow-volume loop recorder on a NDD EasyOne Pro system before and after bronchodilator administration.

Intervention type: PROCEDURE
Intervention: PFT
Description: Lung function endpoints of FVC, FEV1, FEV1/FVC, and FEF25-75% will be measured with the flow-volume loop recorder on a NDD EasyOne Pro system before and after bronchodilator administration.

Intervention type: PROCEDURE
Intervention: PFT
Description: Lung function endpoints of FVC, FEV1, FEV1/FVC, and FEF25-75% will be measured with the flow-volume loop recorder on a NDD EasyOne Pro system before and after bronchodilator administration.

Intervention type: PROCEDURE
Intervention: PFT
Description: Lung function endpoints of FVC, FEV1, FEV1/FVC, and FEF25-75% will be measured with the flow-volume loop recorder on a NDD EasyOne Pro system before and after bronchodilator administration.

Intervention type: PROCEDURE
Intervention: lab work
Description: The blood will be processed for serum, plasma, and PBMCS, and a portion stored to be used for future use. A hemoglobin and Carboxyhemoglobin will be done in order to calculate the DLCO.

Intervention type: PROCEDURE
Intervention: lab work
Description: The blood will be processed for serum, plasma, and PBMCS, and a portion stored to be used for future use. A hemoglobin and Carboxyhemoglobin will be done in order to calculate the DLCO.

Intervention type: PROCEDURE
Intervention: lab work
Description: The blood will be processed for serum, plasma, and PBMCS, and a portion stored to be used for future use. A hemoglobin and Carboxyhemoglobin will be done in order to calculate the DLCO.

Intervention type: PROCEDURE
Intervention: lab work
Description: The blood will be processed for serum, plasma, and PBMCS, and a portion stored to be used for future use. A hemoglobin and Carboxyhemoglobin will be done in order to calculate the DLCO.

Intervention type: PROCEDURE
Intervention: 6MWT
Description: The six-minute walk tests are performed in a 100-foot segment of straight hallway marked at 1-foot intervals.

Intervention type: PROCEDURE
Intervention: 6MWT
Description: The six-minute walk tests are performed in a 100-foot segment of straight hallway marked at 1-foot intervals.

Intervention type: PROCEDURE
Intervention: 6MWT
Description: The six-minute walk tests are performed in a 100-foot segment of straight hallway marked at 1-foot intervals.

Intervention type: PROCEDURE
Intervention: 6MWT
Description: The six-minute walk tests are performed in a 100-foot segment of straight hallway marked at 1-foot intervals.

Intervention type: OTHER
Intervention: questionnaires
Description: TEAL, MMRC and ST. George's Questionnaire will be administered. They are paper questionnaires that inquire about respiratory symptoms, quality of life, smoking history and other health issues

Intervention type: OTHER
Intervention: questionnaires
Description: TEAL, MMRC and ST. George's Questionnaire will be administered. They are paper questionnaires that inquire about respiratory symptoms, quality of life, smoking history and other health issues

Intervention type: OTHER
Intervention: questionnaires
Description: TEAL, MMRC and ST. George's Questionnaire will be administered. They are paper questionnaires that inquire about respiratory symptoms, quality of life, smoking history and other health issues