Study: NCT02141763

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 40 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: UCB4940 40 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 80 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 80 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: UCB4940 80 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 160 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 160 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: UCB4940 160 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 240 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: UCB4940 240 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 320 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: UCB4940 320 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UCB4940 560 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: UCB4940 560 mg
Description: * Active Substance: UCB4940~* Pharmaceutical Form: solution~* Concentration: vials at 80 mg/mL will be diluted with 0.9 % sodium chloride to a final concentration calculated to achieve the correct dose~* Route of Administration: intravenous

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: * Pharmaceutical Form: solution~* Concentration: 0.9 % sodium chloride~* Route of Administration: intravenous

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: * Pharmaceutical Form: solution~* Concentration: 0.9 % sodium chloride~* Route of Administration: intravenous

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: * Pharmaceutical Form: solution~* Concentration: 0.9 % sodium chloride~* Route of Administration: intravenous

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: * Pharmaceutical Form: solution~* Concentration: 0.9 % sodium chloride~* Route of Administration: intravenous