Study: NCT03246724

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: This will be used for intravenous sedation. This injection or sodium chloride 0.9% will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1.0 mg~Dose for BMI greater than or equal to 35: 2.0 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: This will be used for intravenous sedation. This injection or sodium chloride 0.9% will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1.0 mg~Dose for BMI greater than or equal to 35: 2.0 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: This will be used for intravenous sedation. This injection or sodium chloride 0.9% will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1.0 mg~Dose for BMI greater than or equal to 35: 2.0 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microcrystalline Cellulose
Description: This will be used for the oral placebo. This capsule or a triazolam capsule will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1 capsule~Dose for BMI greater than or equal to 35: 2 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microcrystalline Cellulose
Description: This will be used for the oral placebo. This capsule or a triazolam capsule will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1 capsule~Dose for BMI greater than or equal to 35: 2 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microcrystalline Cellulose
Description: This will be used for the oral placebo. This capsule or a triazolam capsule will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1 capsule~Dose for BMI greater than or equal to 35: 2 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microcrystalline Cellulose
Description: This will be used for the oral placebo. This capsule or a triazolam capsule will be administered depending on the randomized treatment group.~Dose for BMI less than 35: 1 capsule~Dose for BMI greater than or equal to 35: 2 capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium chloride 0.9%
Description: This will be used for the intravenous placebo.This injection or midazolam will be administered depending on the randomized treatment group.~Dose for BMI less than 35: volume to match volume of active intravenous medication~Dose for BMI greater than or equal to 35: volume to match volume of active intravenous medication

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium chloride 0.9%
Description: This will be used for the intravenous placebo.This injection or midazolam will be administered depending on the randomized treatment group.~Dose for BMI less than 35: volume to match volume of active intravenous medication~Dose for BMI greater than or equal to 35: volume to match volume of active intravenous medication

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium chloride 0.9%
Description: This will be used for the intravenous placebo.This injection or midazolam will be administered depending on the randomized treatment group.~Dose for BMI less than 35: volume to match volume of active intravenous medication~Dose for BMI greater than or equal to 35: volume to match volume of active intravenous medication

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium chloride 0.9%
Description: This will be used for the intravenous placebo.This injection or midazolam will be administered depending on the randomized treatment group.~Dose for BMI less than 35: volume to match volume of active intravenous medication~Dose for BMI greater than or equal to 35: volume to match volume of active intravenous medication