TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03665051

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Muscle Tissue Biopsy
Description: A biopsy of the Vastus Lateralis muscle will be performed on the left leg using the Bergstrom technique.The skin will be incised (approximately 0.75 cm) with a #11 scalpel, and the Bergstrom needle will be inserted into the Vastus Lateralis. Approximately 150 mg of muscle tissue will be obtained under suction. After the biopsy, pressure will be applied to stop bleeding and the skin will be closed with Steri strips (suture(s) if allergy to steri strips and removal 7-10 days post biopsy). A sterile dressing will be applied. Ace bandage may also be used along with applied pressure and an ice pack for any swelling and pain relief.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Muscle Tissue Biopsy
Description: A biopsy of the Vastus Lateralis muscle will be performed on the left leg using the Bergstrom technique.The skin will be incised (approximately 0.75 cm) with a #11 scalpel, and the Bergstrom needle will be inserted into the Vastus Lateralis. Approximately 150 mg of muscle tissue will be obtained under suction. After the biopsy, pressure will be applied to stop bleeding and the skin will be closed with Steri strips (suture(s) if allergy to steri strips and removal 7-10 days post biopsy). A sterile dressing will be applied. Ace bandage may also be used along with applied pressure and an ice pack for any swelling and pain relief.

Intervention type: OTHER
Group type: OTHER
Intervention: Maximal Oxygen Consumption (V02max)
Description: Aerobic fitness will be determined by measuring maximal O2 consumption (VO2max) during a stationary bicycle exercise test. Heart rate, blood pressure and ECG will be recorded throughout this test. Subjects will breathe through a low resistance mouthpiece and wear a nose clip. Expired gases will be measured by indirect calorimetry and heart rate monitored by a portable heart rate monitor. Following a standardized warm up, subjects will begin exercising at a moderate intensity with the workload increased every minute until the subject can no longer continue. A leveling-off (plateau) or decline in oxygen uptake should be demonstrated in order to be reasonably sure that a subject has achieved the maximum capacity for aerobic metabolism.

Intervention type: OTHER
Group type: OTHER
Intervention: Maximal Oxygen Consumption (V02max)
Description: Aerobic fitness will be determined by measuring maximal O2 consumption (VO2max) during a stationary bicycle exercise test. Heart rate, blood pressure and ECG will be recorded throughout this test. Subjects will breathe through a low resistance mouthpiece and wear a nose clip. Expired gases will be measured by indirect calorimetry and heart rate monitored by a portable heart rate monitor. Following a standardized warm up, subjects will begin exercising at a moderate intensity with the workload increased every minute until the subject can no longer continue. A leveling-off (plateau) or decline in oxygen uptake should be demonstrated in order to be reasonably sure that a subject has achieved the maximum capacity for aerobic metabolism.
Study: NCT02849756

Intervention type: OTHER
Intervention: older in intensive care unit
Description: It is an observational study with no intervention.
Study: NCT00570102

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: A highly hydrolyzed formula
Description: Weaning to a highly hydrolyzed formula, avoidance of all supplemental food containing cow's milk proteins and/or bovine serum albumin up to the age of 6-8 months

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: A regular cow's milk based formula
Description: Weaning to a regular cow's milk based formula supplemented with 20% of the highly hydrolyzed formula used in arm 1 to make the study formulas similar in smell and taste, avoidance of all supplemental food containing cow's milk proteins and/or bovine serum albumin
Study: NCT03419715

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bimatoprost Topical Solution
Description: One drop of bimatoprost topical solution is applied daily to the lunula region of the fingernail bed

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: One drop of saline solution is applied daily to the lunula of the fingernail bed on one hand.
Study: NCT02087787

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BMT Legal Clinic
Description: 2 hour consultation with an attorney in the BMT Legal Clinic with potential follow-up as needed.
Study: NCT03783260

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet
Description: During both Mediterranean diet periods, participants will be provided with meals and snacks representative of the Mediterranean nutritional habits. Participants will be required to eat only the meals provided.
Study: NCT04203485

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Camrelizumab 200mg
Description: Camrelizumab 200mg q2w ivgtt

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Camrelizumab 200mg
Description: Camrelizumab 200mg q2w ivgtt

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apatinib Mesylate 250mg
Description: Apatinib Mesylate 250mg po qd

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pemetrexed disodium for injection
Description: Pemetrexed disodium for injection 500 mg/m2 q3w

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel injection
Description: Paclitaxel injection 175 mg/m2 q3w
Study: NCT02351427

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Steroid
Description: Investigators administer steroid in both groups for conventional treatment of acute cellular rejection.
Study: NCT04203485

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Carboplatin AUC 5 mg/mL/min q3w
Study: NCT01392807

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-118
Description: 25 mg Oral tablets, single dose
Study: NCT03297411

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Brief Temporoparietal ECT
Description: Electroconvulsive Therapy (Brief pulse width, Temporoparietal) The intervention in this study is different combinations of pulse width and ECT electrode placements.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrabrief Temporoparietal ECT
Description: Electroconvulsive Therapy (Ultrabrief pulse width, Temporoparietal) The intervention in this study is different combinations of pulse width and ECT electrode placements.
Study: NCT01392807

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-118
Description: 25 mg Oral tablets, single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-118
Description: 25 mg Oral tablets, single dose
Study: NCT04557852

Intervention type: PROCEDURE
Intervention: ATVM
Description: Tailored anterior transvaginal mesh for pelvic organ prolapse
Study: NCT02416557

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PEEP
Description: application of 10 cmH2O (centimeter of water) positive end expiratory pressure during mechanical ventilation
Study: NCT04528121

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CoDuSe balance training and step square exercises
Description: The standardized intervention targeted visual, somatosensory, and vestibular aspects of balance and will be included with balance exercises~Examples of core stability exercises as follows: in supine position with knees bent, slowly slide one heel forward to straighten leg; and, in four-point kneeling position, slide one foot in a straight line away from the body and lift the leg off the floor.~Examples of dual-task exercises as walking while turning one's head and juggling a balloon.~Examples of sensory strategies as standing and walking on uneven surfaces and standing with eyes closed.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional balance training
Description: static and dynamic balance training exercises from sitting, standing and ambulation activities
Study: NCT03297411

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Brief Frontoparietal ECT
Description: Electroconvulsive Therapy (Brief pulse width, Frontoparietal) The intervention in this study is different combinations of pulse width and ECT electrode placements.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrabrief Frontoparietal ECT
Description: Electroconvulsive Therapy (Ultrabrief pulse width, Frontoparietal) The intervention in this study is different combinations of pulse width and ECT electrode placements.
Study: NCT00945828

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Annual Intervention Group
Description: Parents/caregivers and the teacher of participants will be asked to evaluate the effectiveness of the child's IEP once per academic calendar year. The evaluation is done through the use of an IEP Questionnaire developed for this study. This questionnaire addresses the child's academic performance, progress, and adherence to the IEP developed.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Quarterly Monitoring of IEP
Description: Parents/caregivers and the teacher of participants will be asked to evaluate the effectiveness of the child's IEP four times per academic calendar year. The evaluation is done through the use of an IEP Questionnaire developed for this study. This questionnaire addresses the child's academic performance, progress, and adherence to the IEP developed.
Study: NCT04528121

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional balance training
Description: static and dynamic balance training exercises from sitting, standing and ambulation activities
Study: NCT00661271

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based stress reduction (MBSR)
Description: 8 weekly sessions with instruction designed to enhance mindfulness--mindful meditation, mindful yoga, and discussion of mindfulness practice, with one retreat session.
Study: NCT02076425

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PCIT-ED
Study: NCT03219775

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab/Ipilimumab
Description: * Induction: Mono-Therapy with Nivolumab (240 mg i.V. / Q2W x 4)~* If CR/PR: Nivolumab Maintenance Mono-Therapy (240 mg i.V. / Q2W)~* If SD/PD: Nivolumab/Ipilimumab Boost 1+2-Combination Therapy (Nivo1 mg/kg i.V. and Ipi3 mg/kg i.V. / Q3W x 2)\*~* If CR/PR: Nivolumab Maintenance Mono-Therapy (240 mg i.V. / Q2W)~* If SD/PD: Nivolumab/Ipilimumab Boost 3+4-Combination Therapy (Nivo 1 mg/kg i.V. and Ipi 3 mg/kg i.V. / Q3W x 2)~* If CR/PR/SD: Nivolumab Maintenance Mono-Therapy (240 mg i.V. / Q2W)~  * since June 5, 2019, the treatment in all four boost cycles (1+2) and (3+4) is performed with nivolumab 1 mg/kg + ipilimumab 3 mg/kg (NIVO1/IPI3)
Study: NCT00661271

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy topics
Description: 8 week health education program with one retreat session
Study: NCT04279106

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 0.05%chlorhexidine mouthwash
Description: All subjects were instructed to rinse once a day, in the morning, with 15 ml solution for 60 seconds, after which they expectorated. Subsequent rinsing with water was not allowed.
Study: NCT00136591

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bortezomib
Description: Arm A: a 21-day cycle of 1.5 mg/m2 Velcade™ twice weekly for 2 weeks. Days 1, 4, 8, and 11 of a 21-day cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Arm B: a 35-day cycle of 1.6 mg/m2 Velcade™once weekly for 4 weeks. Days 1, 8, 15, and 22 of a 35-day cycle. Subjects in this treatment arm will receive a total of 6 cycles of treatment, approximately 30 weeks.
Study: NCT04503876

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Increasing PEEP setting
Description: End expiratory lung volume and lung aeration measurements will be conducted using electrical impedance tomography and nitrogen washin-washout method. Measurements will be conducted during the last minute of each step.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Decreasing PEEP setting
Description: End expiratory lung volume and lung aeration measurements will be conducted using electrical impedance tomography and nitrogen washin-washout method. Measurements will be conducted during the last minute of each step.
Study: NCT02076542

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education - Diabetes and Sports
Description: Based on the treatment and education programme PRIMAS a problem-specific education module regarding Diabetes and Sports was created. The module covers specific and detailed aspects of the topic sports such as insulin reduction, hypoglycemia awareness during physical activity, and blood glucose values prior to physical activity. With this module, a more comprehensive education of patients with specific interest is possible.
Study: NCT02702648

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AC-082
Description: Hard gelatin capsules for oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AC-082
Description: Hard gelatin capsules for oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo capsules for oral administration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo capsules for oral administration
Study: NCT01164722

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: clinical observation
Description: Patients undergo observation

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: infrared photocoagulation therapy
Description: Anal infrared coagulator ablation
Study: NCT04279106

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 0.05% sodium fluoride mouthwash
Description: All subjects were instructed to rinse once a day, in the morning, with 15 ml solution for 60 seconds, after which they expectorated. Subsequent rinsing with water was not allowed.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: alcohol free essential oils mouthwash
Description: All subjects were instructed to rinse once a day, in the morning, with 15 ml solution for 60 seconds, after which they expectorated. Subsequent rinsing with water was not allowed.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: All subjects were instructed to rinse once a day, in the morning, with 15 ml solution for 60 seconds, after which they expectorated. Subsequent rinsing with water was not allowed.
Study: NCT00680641

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Simvastatin
Description: 40mg of Simvastatin once daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 40mg of placebo once daily
Study: NCT01395524

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-118
Description: 12.5 mg oral tablet once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-118
Description: 25 mg oral tablet once daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral tablet intake once daily
Study: NCT06529926

Intervention type: OTHER
Group type: OTHER
Intervention: Observational
Description: Only classical physiotherapy application for 4 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IASTM Technique Application
Description: IASTM application for 2 sessions per week with classical physiotherapy for 4 weeks.
Study: NCT01149668

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PCI-24781
Description: Subjects enrolled in this study will receive PCI-24781 administered orally at the schedule and dosage from their prior protocol.
Study: NCT04384133

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Impulse oscillometry
Description: Impulse oscillometry is a pulmonary function test. During the test, the participant is told to breathe normally.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Impulse oscillometry
Description: Impulse oscillometry is a pulmonary function test. During the test, the participant is told to breathe normally.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Impulse oscillometry
Description: Impulse oscillometry is a pulmonary function test. During the test, the participant is told to breathe normally.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Spirometric pulmonary function test
Description: In the spirometric pulmonary function test, the participant is asked to perform respiratory maneuvers such as breathing deeply.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Spirometric pulmonary function test
Description: In the spirometric pulmonary function test, the participant is asked to perform respiratory maneuvers such as breathing deeply.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Spirometric pulmonary function test
Description: In the spirometric pulmonary function test, the participant is asked to perform respiratory maneuvers such as breathing deeply.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Fractional exhaled nitric oxide (FENO) test
Description: In the FENO test, the participant is asked to perform respiratory maneuvers such as breathing deeply.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Thorax Computed Tomography
Description: Computed tomography is a radiological examination.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Chest X Ray
Description: Chest X ray is a radiological examination.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Chest X Ray
Description: Chest X ray is a radiological examination.

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Blood eosinophil level
Description: A tube of blood will be drawn from the participant.

Intervention type: OTHER
Group type: OTHER
Intervention: CAT
Description: It consists of 8 questions.
Study: NCT00999908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indacaterol 150 μg
Description: Indacaterol was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indacaterol 150 μg
Description: Indacaterol was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indacaterol 150 μg
Description: Indacaterol was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tiotropium 18 μg
Description: Tiotropium was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tiotropium 18 μg
Description: Tiotropium was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tiotropium 18 μg
Description: Tiotropium was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.
Study: NCT04384133

Intervention type: OTHER
Group type: OTHER
Intervention: mMRC
Description: It is the scale used to measure the severity of shortness of breath.
Study: NCT02602756

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Protontherapy
Description: Proton-therapy consists in four consecutive sessions. The experimental arm consists in eight sessions. Irradiation is administered over two weeks, delivering a total dose of 60 Cobalt Gris Equivalent (CGE is the physical Gray dose multiplied by a biological factor of relative efficiency of 1.1 for protons compared to photons).

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Protontherapy
Description: Proton-therapy consists in four consecutive sessions. The experimental arm consists in eight sessions. Irradiation is administered over two weeks, delivering a total dose of 60 Cobalt Gris Equivalent (CGE is the physical Gray dose multiplied by a biological factor of relative efficiency of 1.1 for protons compared to photons).
Study: NCT00999908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo (matching indacaterol) was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.
Study: NCT04635800

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHU650
Description: MHU650 powder for solution for injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHU650
Description: MHU650 powder for solution for injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHU650
Description: MHU650 powder for solution for injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHU650
Description: MHU650 powder for solution for injection
Study: NCT03796520

Intervention type: DIAGNOSTIC_TEST
Intervention: EpiPick simplified seizure classification algorithm
Description: EpiPick simplified seizure classification algorithm input:~Grey matter brain lesion Exclusively nocturnal seizures First seizure at age \> 20 years Lip smacking or chewing during seizures Staring with impaired awareness, lasting less than 20s without postictal confusion Sudden irregular jerks, in isolation or brief series, if none of the following applies: Are the jerks consistently in the same limb? When resting in bed when falling asleep? Bilateral tonic-clonic seizures within 1h of awakening or immediately preceded by irregular jerks Any of the following is present: Skin turning pale pre-ictally; Loss of consciousness immediately after urination or defecation; Sudden slump with loss of awareness, lasting less than 10 seconds; Seizure lasting longer than 10 minutes, with eyes closed throughout the seizure; Severe pre-ictal headache; Episodes consisting of falls that occur always after change in posture to the upright position, or coughing or feeling pain.
Study: NCT00999908

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo (matching indacaterol) was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo (matching indacaterol) was supplied in powder filled capsules together with a single dose dry powder inhaler (SDDPI) device.
Study: NCT02254889

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: proton pump inhibitor
Description: ). In the pre-ESD therapeutic group, a standard intravenous dose of PPI was given 2 hours before ESD. In the post-ESD therapeutic group, patients also received intravenous PPI in standard doses, once in the evening after ESD.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: proton pump inhibitor
Description: ). In the pre-ESD therapeutic group, a standard intravenous dose of PPI was given 2 hours before ESD. In the post-ESD therapeutic group, patients also received intravenous PPI in standard doses, once in the evening after ESD.
Study: NCT00624390

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sepraspray