TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05670522

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation
Description: Transcranial direct-current stimulation (tDCS), over the motor cortex, is a potential therapy option for motor control deficits in children with CP. The application of tDCS involves positioning 2 rubber electrodes sheathed in saline-soaked pads onto the scalp, held in place by a rubber strap. Low-intensity, direct-current, of 1 to 2 mA, is delivered to cortical areas from the device.~The standard-of-care gait training included various gait training and balance tasks as well as resistive exercises and passive stretching as necessary. Task-specific gait exercises included: walking in a closed indoor environment, walking in an open indoor environment, walking on various floor surfaces, and climbing stairs up and down without assistance. The children also performed dynamic balance exercises by walking on a balance board.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Virtual reality rehabilitation is an emerging therapy for motor rehabilitation of children with CP. The therapy is provided through a computer-simulated environment where they interact with real-world-like objects and events through sight, sound, and touch. The Wii Remote was used as the interactive interface, and standard computer/television screens were used as the display hardware. Therefore, VR therapy was of the non-immersive type.~The standard-of-care gait training included various gait training and balance tasks as well as resistive exercises and passive stretching as necessary. Task-specific gait exercises included: walking in a closed indoor environment, walking in an open indoor environment, walking on various floor surfaces, and climbing stairs up and down without assistance. The children also performed dynamic balance exercises by walking on a balance board.
Study: NCT04113850

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile Acoustic startle Reflex monitoring System (MARS)
Description: Acoustic startle testing

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile Acoustic startle Reflex monitoring System (MARS)
Description: Acoustic startle testing
Study: NCT03957148

Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sugar-sweetened beverage reduction education for preschool children
Description: Participants in the SSB-IMB program will receive 10 weeks of SSB related nutrition education at their child's preschool. Each week a different lesson pertaining to parental information, motivation, or behavioral skills related to SSBs will be presented via an interactive display board. Twice a week, two student educators will stand by display boards for two hours and deliver the lessons that will last 5-10 minutes with each parent. These displays will include an activity for parents to apply knowledge and skills learned during the short lesson. Educators will also provide parents with informational handouts pertaining to each lesson to reinforce concepts learned. Display board education is flexible, so that if a parent arrives while another parent is receiving education, the second educator can begin the lesson with the new parent. Multiple parents can participate in a lesson at the same time. Groups of 2-3 parents can review the lesson together, learning from each other.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sugar-sweetened beverage reduction education for preschool children
Description: Participants in the SSB-IMB program will receive 10 weeks of SSB related nutrition education at their child's preschool. Each week a different lesson pertaining to parental information, motivation, or behavioral skills related to SSBs will be presented via an interactive display board. Twice a week, two student educators will stand by display boards for two hours and deliver the lessons that will last 5-10 minutes with each parent. These displays will include an activity for parents to apply knowledge and skills learned during the short lesson. Educators will also provide parents with informational handouts pertaining to each lesson to reinforce concepts learned. Display board education is flexible, so that if a parent arrives while another parent is receiving education, the second educator can begin the lesson with the new parent. Multiple parents can participate in a lesson at the same time. Groups of 2-3 parents can review the lesson together, learning from each other.
Study: NCT00934453

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lactobacillus rhamnosus GG ATCC 53103
Description: Study drug capsules (1x10\^10 LGG/capsule) are to be taken orally twice a day every day dissolved in cow's milk or soy milk on an outpatient basis for six months.

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsules composed of microcrystalline cellulose are to be taken orally twice a day dissolved in cow's milk or soy milk on an outpatient basis for six months.
Study: NCT03899714

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cryotherapy
Description: Crushed ice in a plastic bag will be used, as it is a widely accessible and financially convenient method of cryotherapy. One half of a kilogram of ice will be placed in a plastic bag. The plastic bags will be 17 cm wide and 22 cm long. The air will be squeezed out of the bag and it will be sealed. The bag will be wrapped in a wet towel and applied to the tested area. Every five bags of crushed ice will be kept in an insulated foam container containing one kilogram of dry ice. Dry ice has a temperature of negative 80 degrees Celsius, and is used to keep the bags of crushed ice in a frozen state till the participants are briefed and the testing began.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cryotherapy
Description: Crushed ice in a plastic bag will be used, as it is a widely accessible and financially convenient method of cryotherapy. One half of a kilogram of ice will be placed in a plastic bag. The plastic bags will be 17 cm wide and 22 cm long. The air will be squeezed out of the bag and it will be sealed. The bag will be wrapped in a wet towel and applied to the tested area. Every five bags of crushed ice will be kept in an insulated foam container containing one kilogram of dry ice. Dry ice has a temperature of negative 80 degrees Celsius, and is used to keep the bags of crushed ice in a frozen state till the participants are briefed and the testing began.
Study: NCT04816448

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cervical mobilization (Headache SNAG)
Description: For cervical mobilization the patient's position is sitting on a chair in the erect posture. The therapist handled C2 spinous process with the middle phalanx of one hand. With the other hand, he performed ventral glide asked the patient to move neck in all directions (Flexion, Extension, Side bending and rotation) one by one and then slowly move the neck back to its starting position while the therapist maintained the ventral glide.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sub-occipital myofascial release
Description: For the application of the technique , the patient position is supine lying with the head fully supported on therapist's hands and therapist places 3 middle fingers just inferior to the nuchal line, lifts the fingers tips towards the ceiling while resting the head on the table and then therapist will apply a gentle upward pull. This procedure done for 2 to 3 minutes and 5 to 7 repetitions, 3 sessions per week on alternate days were given for 6 weeks.~Evaluation was done before treatment, during treatment at 4th week and after treatment at 6th week. Outcomes will be measured by NDI, PNRS and Universal Goniometer.
Study: NCT02462044

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 240 mg Iodine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 300 mg Iodine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 370 mg Iodine
Study: NCT02710656

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Legflow® balloon
Description: Percutaneous angioplasty performed with a Drug coated balloon (DCB) with Paclitaxel

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard PTA
Description: Percutaneous angioplasty performed with a standard balloon
Study: NCT00683111

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: esomeprazole 20 mg daily
Description: oral famotidine 40 mg daily vs. oral esomeprazole 20 mg daily for up to 12 months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: famotidine 40 mg daily
Description: oral famotidine 40 mg daily vs. oral esomeprazole 20 mg daily for up to 12 months
Study: NCT03072446

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gel-Beads embolic material
Description: Patients will receive embolization of their uterine fibroids using Gel-Beads.
Study: NCT02027012

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percutaneous renal denervation with the Vessix™ Renal Denervation System
Study: NCT04013308

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Iontophoresis with 2% potassium iodide
Description: 10 iontophoresis treatments with 2% potassium iodide on the area of thyroid gland; electrodes with tin foil (Amperage:2mA, duration: 30min)
Study: NCT03853330

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound
Description: Ultrasound-guided Thoracic Epidural Analgesia and Erector spinae plane block.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound
Description: Ultrasound-guided Thoracic Epidural Analgesia and Erector spinae plane block.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl Inj 0.25%
Description: Bupivacaine HCl Inj 0.25% will be used in both blocks by the same dose of 7.5-12 ml

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine HCl Inj 0.25%
Description: Bupivacaine HCl Inj 0.25% will be used in both blocks by the same dose of 7.5-12 ml

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution
Description: infusion of Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution at 5-7 ml/h will be used in both blocks and also for breakthrough pain after both blocks as a bolus of 5-10 ml.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution
Description: infusion of Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution at 5-7 ml/h will be used in both blocks and also for breakthrough pain after both blocks as a bolus of 5-10 ml.
Study: NCT03806192

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telephone-Based Intervention
Description: Attend psychoeducational counseling sessions via telephone

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Behavioral, Psychological or Informational Intervention
Description: Attend psychoeducational counseling sessions via video teleconference

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT03032562

Intervention type: DIAGNOSTIC_TEST
Intervention: Multimodal measurement of respiratory muscle function and strength
Description: Sleep-studies, capnography, spiromanometry, phrenic nerve conduction studies, magnetic phrenic nerve stimulation, diaphragmatic ultrasound

Intervention type: DIAGNOSTIC_TEST
Intervention: Multimodal measurement of respiratory muscle function and strength
Description: Sleep-studies, capnography, spiromanometry, phrenic nerve conduction studies, magnetic phrenic nerve stimulation, diaphragmatic ultrasound
Study: NCT02732600

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facilitated Implementation
Description: Facilitated Implementation sites will receive one year of support based on the i-PARIHS implementation model which includes training, implementation planning, ongoing external facilitation, feedback and consultation
Study: NCT01258777

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 400 mg golimumab or placebo
Description: Single dose of 400 mg subcutaneously

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 200 mg golimumab or placebo
Description: Single dose of 200 mg subcutaneously
Study: NCT03289793

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurofeedback training
Description: Children in group A will receive BCI-based training implemented through original P300-based controlled games.~They will attend 30 1-hour long training sessions at a pace of 2 sessions per week.~Each session includes: installation of the child, the EEG system and an eye-tracking system, a 5-minutes relaxation phase, a short EEG recording at rest, a brief reminder of the instructions, 30 minutes of training by playing video games and finally a time for the child to wash her/his hair.~Moreover, 4 neuropsychological sessions will complement the 30 training sessions. During these sessions neuropsychological tests and quality of life questionnaires will be answered.
Study: NCT02341131

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Remediation Therapy
Description: The program has a duration of 40 sessions (one hour of duration), with two sessions for week during four months. It is carried out individually and utilizes paper and pencil tasks. The main technique utilized is the scaffolding (to provide strategies when the patient cannot carry out the task and to withdraw him when he is yet able of doing it alone) in a context of learning without errors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychoeducation
Description: The program has a duration of 40 sessions (one hour of duration), with two sessions for week during four months. It is carried out individually and utilizes teaching information and coping skills and neuropsychological issues are not addressed.
Study: NCT03309462

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Miseq sequencer
Description: The sequencer will be used to detect the gene mutations of the re-biopsy tissue samples and peripheral blood samples obtained from patients.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Miseq sequencer
Description: The sequencer will be used to detect the gene mutations of the re-biopsy tissue samples and peripheral blood samples obtained from patients.
Study: NCT04326166

Intervention type: DRUG
Intervention: Evogliptin
Description: Evogliptin

Intervention type: DRUG
Intervention: Evogliptin
Description: Evogliptin
Study: NCT03289793

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Sham control
Description: Children in group B will receive a training that is not based on brain activity, but in a blind fashion. They will attend 30 1-hour long training sessions at a pace of 2 sessions per week.~Each session includes: installation of the child, setting up the EEG and eye-tracking systems, a 5-minutes relaxation phase, short EEG recording at rest, a brief reminder of the instructions, 30 minutes of video game based training and finally a time for the child to wash her/his hair.~Besides, 4 neuropsychological sessions will complement the 30 training sessions. During these sessions neuropsychological tests and quality of life questionnaires will be performed.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Baseline control group
Description: The children included in this group will not receive any training. They only take part to the 4 neuropsychological sessions. Like others, they will attend 1 neuropsychological session every two months over six months.
Study: NCT02826746

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium Sulfate
Description: adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: the same bolus and infusion volumes of normal saline
Study: NCT02919228

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visible light exposure
Description: Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.
Study: NCT03630796

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: Use of sevoflurane (compared to total intravenous anesthesia) in congenital heart deffects surgeries.

Intervention type: DRUG
Group type: OTHER
Intervention: TIVA
Description: Total intravenous anesthesia
Study: NCT05039749

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Human Centric Lights
Description: Bright light is emitted during the day from 06:00, then auto-dimmed light is used at night, beginning 19:00.
Study: NCT04279886

Intervention type: OTHER
Group type: OTHER
Intervention: Three-dimensional scans
Description: All included healthy volunteers received 6 three-dimensional scans, utilizing 3 different scanning systems (2 scans per system)
Study: NCT03820544

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic Retrograde Cholangiopancreatography
Description: Undergo ERCP with SEMS placement

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Undergo standard of care surgical resection
Study: NCT03771755

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuprofen
Description: 800 mg IV - Ibuprofen every 6 hours. In case required - followed with Morphine (PCA) 1-2 mg every 5 minutes

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Acetaminophen
Description: 1000mg IV Acetaminophen every 6 hours. In case required - followed with Morphine (PCA) 1-2 mg every 5 minutes
Study: NCT01386164

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Gardasil
Description: Subjects will receive three doses of the study vaccine administered intramuscularly according to a Day 0, Week 6, and Month 6 vaccination schedule.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cervarix
Description: Subjects will receive three doses of the study vaccine administered intramuscularly according to a Day 0, Week 6, and Month 6 vaccination schedule.
Study: NCT03678272

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HERNIOPLASTY WITH PANAVALE MESH
Description: Polypropylene mesh fixed with 3 points. Preformed polypropylene mesh will be used by fixing it with one point to the pubis, another to the inguinal ligament and another to the joint tendon.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HERNIOPLASTY WITH PARIETEX PROGRIP MESH
Description: Preformed polypropylene mesh will be used which presents a self adhesive system not based on glue, but on the arrangement of the fibers of the mesh as hooks, and to which we will give a single point to the pubis.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HERNIOPLASTY WITH ADHESIX MESH
Description: It will use a self-adhesive mesh without giving points to fix this one, since it is a mesh that integrates the glue.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HERNIOPLASTY WITH TIMESH MESH
Description: Titaniumized polypropylene mesh will be used without fixing points, since liquid cyanoacrylate (Ifabond) will be used to fix it.
Study: NCT00531765

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: sodium bicarbonate infusion
Description: short infusion of sodium bicarbonate

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sodium bicarbonate infusion
Description: short infusion of sodium bicarbonate
Study: NCT01539759

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Immediate Postplacental Placement of an IUD during cesarean delivery
Description: Women randomized to this arm will have an IUD placed during their cesarean delivery, immediately after delivery of the placenta
Study: NCT03602677

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ICG fluorescence imaging
Description: The use of indocyanine green fluorescence imaging as an addition to standard surgical procedure.
Study: NCT01862146

Intervention type: PROCEDURE
Intervention: smoke expose
Study: NCT00871767

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5672
Description: 40 mg tablet (Test formulation)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5672
Description: 40 mg tablet (Reference formulation)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5672
Description: 100 mg tablet (Test formulation)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5672
Description: 100 mg (2 x 50 mg tablet (Reference Formulation)
Study: NCT04508946

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: vitamin c - thiamine- hydrocortisone
Description: Triple therapy regimen (vitamin c - thiamine- hydrocortisone)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: vitamin c - thiamine- hydrocortisone
Description: Triple therapy regimen (vitamin c - thiamine- hydrocortisone)
Study: NCT01335776

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction
Description: This intervention is provided over the course of eight, weekly, 90 minute sessions, plus one 6 hour silent retreat.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavior Therapy
Description: This treatment is delivered to small groups over the course of 8 weekly, 90 minute sessions
Study: NCT05195307

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music Group
Description: Pregnant women included in the practice group were given 20 minutes of music every day for ten days. Anxiety and stress levels of pregnant women were measured before and after the intervention.