Study: NCT03974152

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine salt (protonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine salt (protonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine salt (protonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine salt (protonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine salt (protonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine salt (protonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine (unprotonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine (unprotonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine (unprotonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine (unprotonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine (unprotonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subox Mini C with Avail 18 mg nicotine (unprotonated)
Description: Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Own brand cigarette
Description: Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Own brand cigarette
Description: Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Own brand cigarette
Description: Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Own brand cigarette
Description: Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Own brand cigarette
Description: Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Own brand cigarette
Description: Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.