Study: NCT03611101

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ¹³C-Methacetin Breath Test
Description: A breath analyzer will be used to measure changes in 12C (carbon 12) to 13C (carbon 13) ratio as a result of metabolism of the Methacetin substrate before and after treatment.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ¹³C-Methacetin Breath Test
Description: A breath analyzer will be used to measure changes in 12C (carbon 12) to 13C (carbon 13) ratio as a result of metabolism of the Methacetin substrate before and after treatment.

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ¹³C-Methacetin Breath Test
Description: A breath analyzer will be used to measure changes in 12C (carbon 12) to 13C (carbon 13) ratio as a result of metabolism of the Methacetin substrate before and after treatment.

Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: ¹³C-Methacetin Breath Test
Description: A breath analyzer will be used to measure changes in 12C (carbon 12) to 13C (carbon 13) ratio as a result of metabolism of the Methacetin substrate before and after treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986036
Description: Investigational drug for NASH treatment in Main BMS protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986036
Description: Investigational drug for NASH treatment in Main BMS protocol

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986036
Description: Investigational drug for NASH treatment in Main BMS protocol

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: BMS-986036
Description: Investigational drug for NASH treatment in Main BMS protocol

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BreathID MCS device
Description: The BreathID MCS device is a breath analyzer specifically used for measuring changes in the ratio of 13CO2 and 12CO2 isotopes of carbon dioxide. The device is connected to the subject via a nasal cannula and breath is passively collected before and after ingestion of labelled 13C- Methacetin substrate.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BreathID MCS device
Description: The BreathID MCS device is a breath analyzer specifically used for measuring changes in the ratio of 13CO2 and 12CO2 isotopes of carbon dioxide. The device is connected to the subject via a nasal cannula and breath is passively collected before and after ingestion of labelled 13C- Methacetin substrate.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BreathID MCS device
Description: The BreathID MCS device is a breath analyzer specifically used for measuring changes in the ratio of 13CO2 and 12CO2 isotopes of carbon dioxide. The device is connected to the subject via a nasal cannula and breath is passively collected before and after ingestion of labelled 13C- Methacetin substrate.

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: BreathID MCS device
Description: The BreathID MCS device is a breath analyzer specifically used for measuring changes in the ratio of 13CO2 and 12CO2 isotopes of carbon dioxide. The device is connected to the subject via a nasal cannula and breath is passively collected before and after ingestion of labelled 13C- Methacetin substrate.