TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT02620475

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SutureSafe
Description: SutureSafe dressing are designed to apply a constant gentle inward pressure on the incision to reduce separating tension on newly formed incisions, stabilizing the healing environment.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SutureSafe
Description: SutureSafe dressing are designed to apply a constant gentle inward pressure on the incision to reduce separating tension on newly formed incisions, stabilizing the healing environment.
Study: NCT00854789

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: E75 + GM-CSF vaccine
Description: The 1 ml by volume vaccine is administered intradermally in 0.5 ml inoculums at two different sites within 5 cm of each other on an extremity. Vaccinations will be given according to the schedule the patient has been assigned and will be administered in the same lymph node draining area (same arm or thigh). In addition, an optional booster inoculation as requested by previously vaccinated patients will be offered every 6 months for the duration of the protocol. The dose will be determined by the PI based on the patient's response to the initial vaccination series.
Study: NCT02983799

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OLAPARIB
Description: 300 mg olaparib tablets taken orally twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OLAPARIB
Description: 300 mg olaparib tablets taken orally twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OLAPARIB
Description: 300 mg olaparib tablets taken orally twice daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OLAPARIB
Description: 300 mg olaparib tablets taken orally twice daily
Study: NCT01205919

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-based guided self-help for tinnitus
Description: Internet-based guided self-help for tinnitus: provided via Internet, duration of 10 weeks
Study: NCT03805061

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 'aerobic exercise'
Description: The aerobic exercise group by using treadmill their walking speeds were adjusted according to the maximum speed at which the person could walk was performed a period of; 8 weeks, 3 days a week, 30-45 minutes each patient.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 'isokinetic exercise'
Description: Patients in the isokinetic exercise group pedaled a bicycle ergometer for warming with low exercise and exercise was applied for 5-10 minutes to cool down at the end of the study. were included in a rehabilitation program that they would apply for 3 days per week for 8 weeks.The measuring of isokinetic muscle strength, CSMI Humac Norm isokinetic dynamometer's commonly used angular velocities of 60 ° and 180 ° / sec was used.
Study: NCT03942198

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Taodan Granules
Description: Put each bag of medicine in the same amount into the same container, pour about 50 ml of warm water, stir until the particles are basically dissolved, and then add appropriate amount of boiling water to dilute.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Taodan Granules Placebo
Description: Put each bag of medicine in the same amount into the same container, pour about 50 ml of warm water, stir until the particles are basically dissolved, and then add appropriate amount of boiling water to dilute.
Study: NCT04188782

Intervention type: DRUG
Intervention: Sevoflurane
Description: Describe how a reiterative anesthesia exposure could induce tolerance to the anesthetic.
Study: NCT02650856

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group 1 Tranexamic Acid
Description: 2 gr of tranexamic acid will be applied on the surgical site.
Study: NCT03814356

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate
Description: IV MPH
Study: NCT05672940

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic plus resistance training
Description: Aerobic plus resistance training

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stretching plus breathing training
Description: Stretching plus breathing training
Study: NCT03051295

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dental health information form
Description: The format in which dentists receive information about diagnostic test results and efficacy of treatment.
Study: NCT01205919

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Internet discussion forum
Description: Tinnitus-specific internet discussion forum over 10 weeks (no therapeutic intervention)
Study: NCT03051295

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dental health information form
Description: The format in which dentists receive information about diagnostic test results and efficacy of treatment.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dental health information form
Description: The format in which dentists receive information about diagnostic test results and efficacy of treatment.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dental health information form
Description: The format in which dentists receive information about diagnostic test results and efficacy of treatment.
Study: NCT02103127

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 755nm Alexandrite laser with lens array
Study: NCT03663309

Intervention type: DIAGNOSTIC_TEST
Intervention: detecting Gluten peptides in faecal and urine samples
Description: At each visit patient will:~* Bring 4-day food diary (attached)~* Fill symptoms and complaints questionnaire (attached)~* Provide 24 h diet recall in case a food diary absents~* Fill Biagi score questionnaire (attached)~* Perform blood test of TTG~* Provide stool and urine samples
Study: NCT01069393

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DAFNE course (Timing of delivery of education)
Description: Education delivered over one day a week for 5 consecutive weeks, as opposed to 5 consecutive days over 1 week.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: DAFNE course (Timing of delivery of education)
Description: Education delivered over one day a week for 5 consecutive weeks, as opposed to 5 consecutive days over 1 week.
Study: NCT03699566

Intervention type: OTHER
Intervention: Assessment of Respiratory Muscle Strength
Description: The maximal voluntary inspiratory (PImax) and expiratory (PEmax) pressure measurements of the subjects were performed using Cosmed Pony FX model (Italy 2001) while the subjects were in the sitting position with a nose clip.

Intervention type: OTHER
Intervention: Spirometer
Description: Spirometric measurements were conducted with Cosmed, Pony FX (descopt spirometer- Italy 2001) spirometer using a nose clips while the subjects were in 90 degree relaxed sitting position.

Intervention type: OTHER
Intervention: Trunk Muscles Endurance Tests
Description: Trunk muscle endurance of the subjects was measured using four different tests (Side Bridge Test- SBT, Prone Bridge Test- PBT, Flexor Endurance Test- FET, Sorenson Test- ST).
Study: NCT00856635

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glatiramer Acetate
Description: 20 mg injected daily subcutaneously

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: injected daily subcutaneously
Study: NCT04909840

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instructions oral hygiene with toothbrush plus dental floss
Description: Instructions of oral hygiene with toothbrush plus dental floss

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Instructions oral hygiene with toothbrush only
Description: Instructions only with toothbrush
Study: NCT04058015

Intervention type: OTHER
Intervention: Stress-induced hyperglycemia
Description: Stress-induced hyperglycemia (SIH)was defined as a serum glucose ≥ 200 mg/dL in the patients without Diabetes mellitus.

Intervention type: OTHER
Intervention: Diabetic hyperglycemia
Description: Diabetic hyperglycemia (DH) which indicated a serum glucose ≥ 200 mg/dL in patients with Diabetes mellitus.

Intervention type: OTHER
Intervention: Diabetic normoglycemia
Description: Diabetic normoglycemia (DN), which was defined when there was a serum glucose \< 200 mg/dL in the patients with Diabetes mellitus.

Intervention type: OTHER
Intervention: Non-diabetic normoglycemia
Description: Non-diabetic normoglycemia (NDN) indicating a serum glucose \< 200 mg/dL in patients who were absent of Diabetes mellitus.
Study: NCT02424058

Intervention type: DEVICE
Intervention: Spinal Mouse® measurement
Description: The sagittal thoracic spinal curvature and mobility of all participants were assessed with Spinal Mouse® (Idiag, Fehraltorf, Switzerland) in standing position.

Intervention type: DEVICE
Intervention: Spinal Mouse® measurement
Description: The sagittal thoracic spinal curvature and mobility of all participants were assessed with Spinal Mouse® (Idiag, Fehraltorf, Switzerland) in standing position.

Intervention type: BEHAVIORAL
Intervention: Neck pain intensity measurement
Description: The neck pain intensity of the patients was questioned by Visual Analogue Scale
Study: NCT00986791

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GSP-A
Description: 6-week Gold Standard Programme (5 meetings in total) consisting a structured education programme, hotline, thiamine and B-vitamins (300 mg daily), Alcohol Withdrawal Prophylaxis and intervention (Benzodiazepines)and controlled Disulfiram support (200 mg x 2 weekly)
Study: NCT02536144

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: magnetic-controlled capsule endoscopy system
Description: 1. A magnetic-controlled capsule endoscopy(MCCE) included camera,magnet,batter and high polymer material shell.~2. The MCCE would be turned to sleeping mode capturing picture at a rate of 0.5 frame per second after being swallowed.~3. While reaching cecum, the MCCE would be turned to a working mode capturing picture at a rate of 2 frame per second.~4. The MCCE would be controlled by the Magnetic-manipulator out of body to finish the motion of e rotation, somersault, Bird's-eye view, worm's eye view from cecum to anus.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Colonoscopy
Description: 1. Bowel preparation should be well done before the examination.~2. A tube with illumination and camera system would insert into colon from anus.~3. From the pictures captured by the camera ,the doctor would see the mucous of the colon.
Study: NCT02366676

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hyaluronic acid and chondroitin sulphate
Description: IALURIL Intravesical instillation with cystoscope ( 1st month: once a week, 2nd\~5th month:once a month)
Study: NCT00833469

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram
Description: Once daily by mouth
Study: NCT00813917

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: varenicline
Description: 12 weeks of varenicline 1 mg by mouth twice per day

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: 12 weeks of placebo (double blinded) by mouth twice per day
Study: NCT02228044

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prevention program
Study: NCT02650856

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Group 2 Platelet rich plasma
Description: 16ml of platelet rich plasma will be applied of the surgical site
Study: NCT01665911

Intervention type: OTHER
Group type: OTHER
Intervention: Non-fluoridated milk, 200 ml
Description: Each subject will use this product during one of the five treatment periods in the crossover study design.

Intervention type: OTHER
Group type: OTHER
Intervention: Non-fluoridated milk, 200 ml
Description: Each subject will use this product during one of the five treatment periods in the crossover study design.
Study: NCT03450993

Intervention type: OTHER
Group type: OTHER
Intervention: SMART Program
Description: This is an 8-week, multimodal resiliency program that targets stress with 4 main components: mind-body skills (participants learn a variety of meditation techniques, mini relaxations, walking meditation, and yoga), traditional stress management techniques, healthy lifestyle behaviors (sleep, exercise, nutrition, and social support), and cognitive reappraisal and adaptive coping skills (borrowed from cognitive behavioral therapy, acceptance and commitment therapy, and positive psychology)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SMART Program
Description: This is an 8-week, multimodal resiliency program that targets stress with 4 main components: mind-body skills (participants learn a variety of meditation techniques, mini relaxations, walking meditation, and yoga), traditional stress management techniques, healthy lifestyle behaviors (sleep, exercise, nutrition, and social support), and cognitive reappraisal and adaptive coping skills (borrowed from cognitive behavioral therapy, acceptance and commitment therapy, and positive psychology)
Study: NCT01699646

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neoventa S 21 ST-ANalysis of fetal heart
Description: Application of gold-trace scalp electrode

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CTG + FBS
Description: Cardiotocography and fetal blood sampling on/from fetal skalp
Study: NCT03886922

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levcromakalim
Description: Intravenous infusion of levcromakalim or placebo for 20 minutes. To investigate the role of levcromakalim/placebo on cranial arteries in healthy volunteers after glibenclamide administration.
Study: NCT01665911

Intervention type: OTHER
Group type: OTHER
Intervention: Non-fluoridated milk, 200 ml
Description: Each subject will use this product during one of the five treatment periods in the crossover study design.

Intervention type: OTHER
Group type: OTHER
Intervention: Non-fluoridated milk, 200 ml
Description: Each subject will use this product during one of the five treatment periods in the crossover study design.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Non-fluoridated milk, 200 ml
Description: Each subject will use this product during one of the five treatment periods in the crossover study design.
Study: NCT00348946

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: androgen oxandrolone
Description: Oxandrolone ,06 \>mg/kg/day, orally, for 2 years

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: an inactive substance
Study: NCT03677362

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight loss intervention
Description: In the WLI, energy intake will be prescribed at 1200-1500 kcal/d using commercially available portion-controlled entrées, low calorie shakes, fruits/vegetables, and ad-libitum non-caloric beverages. Participants will be asked to consume a minimum daily total of 2 entrées (\~200 to 300 kcal each, saturated fat ≤ 3g), 3 shakes (\~100 kcal each), five 1-cup servings of fruits/vegetables, and ad libitum non-caloric beverages. Additionally, they will be asked to complete 225 min of moderate intensity PA, and self-monitor diet, PA (self-report) and body weight (home scale) across the 6 mo. intervention. Weekly behavioral counseling sessions (45 min) via group phone callsSkype will be delivered by a professional health educator (HE) to participants in their homes.
Study: NCT05483959

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BIPAP mode/SIMV PC mode
Description: BIPAP is a mode of ventilation recently used in ARDS

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BIPAP mode/SIMV PC mode
Description: BIPAP is a mode of ventilation recently used in ARDS
Study: NCT03700164

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temperature
Description: Water-perfused suit.

Intervention type: OTHER
Group type: OTHER
Intervention: Temperature
Description: Water-perfused suit.
Study: NCT02621476

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standardized intervention
Description: Standardized intervention to encourage mail order use and provide easily accessible information on how to access the service

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care
Study: NCT01484496

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Belimumab 200 mg SC
Description: Belimumab 200 mg SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard therapy
Description: Standard therapy comprises any of the following (alone or in combination): corticosteroids, antimalarials, non-steroidal anti-inflammatory drugs (NSAIDs), and immunosuppressives; biologics and intravenous cyclophosphamide are not permitted.
Study: NCT01377883

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: standard
Description: Preparation and information regarding the BTX procedure: placing EMG electrodes, wiping the area with an alcohol swab, cooling with ethyl chloride, needle insertion into the muscle and the importance of EMG noise.~Injection performed under EMG guidance. Two sites of injection per muscle were used to enhance diffusion. The child could often see the procedure when the upper limb was treated but not during lower limb injections.~Memory change and positive reinforcement: Following the BTX injection, the medical staff present spoke to the child positively and offered prizes Volunteer attendance: In the daycare unit there are young volunteers routinely present, assisting with technical aspects of the procedure.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: clown care
Description: Cognitive coping Imagery Empowerment Reflecting emotions
Study: NCT02462460

Intervention type: DEVICE
Intervention: MRI
Study: NCT01484496

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Standard therapy
Description: Standard therapy comprises any of the following (alone or in combination): corticosteroids, antimalarials, non-steroidal anti-inflammatory drugs (NSAIDs), and immunosuppressives; biologics and intravenous cyclophosphamide are not permitted.
Study: NCT02462460

Intervention type: BEHAVIORAL
Intervention: Optional Screening Questionnaire
Study: NCT05202652

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: HealthSpan
Description: The intervention was conducted on a group of healthy volunteers of age 29-85 with a once-daily administration of the oral capsule containing the active ingredients, for three consecutive months.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The intervention was conducted on a group of healthy volunteers of age 29-85 with a once-daily administration of the placebo, for three consecutive months.
Study: NCT01930123

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: intravenous fructose challenge
Description: Patients will be admitted to our Duke Clinical Research Unit (DCRU) at least 12 hours prior to morning intravenous fructose challenge. All patients will have a standard meal in order to control for dietary composition and calorie intake prior to intravenous fructose challenge. Patients will be NPO (nothing by mouth) after midnight for morning IV fructose MR biomarker measures. Patients with suspected NAFLD will have had an historical standard of care liver biopsy in the past and will have IV fructose Magnetic Resonance biomarker measures in the morning.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intravenous fructose challenge
Description: Patients will be admitted to our Duke Clinical Research Unit (DCRU) at least 12 hours prior to morning intravenous fructose challenge. All patients will have a standard meal in order to control for dietary composition and calorie intake prior to intravenous fructose challenge. Patients will be NPO (nothing by mouth) after midnight for morning IV fructose MR biomarker measures. Patients with suspected NAFLD will have had an historical standard of care liver biopsy in the past and will have IV fructose Magnetic Resonance biomarker measures in the morning.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood Draw
Description: Fasting bloodwork will be obtained before and after the IV fructose challenge.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood Draw
Description: Fasting bloodwork will be obtained before and after the IV fructose challenge.
Study: NCT04600375

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Verbal consultation
Description: Verbal consultation only without written information before receiving written action plan

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Written Action Plan
Description: Written handout of treatment plan and disease management strategies

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Written Action Plan
Description: Written handout of treatment plan and disease management strategies
Study: NCT04273204

Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: one leg standing test, gross motor function measurement, pedobarographic measurement
Description: OLST:During the OLST,the participants were asked to shoes off,place both hands on their hips and look at a point on the wall at eye level.A recording stopwatch was used to assess their standing duration on one leg while keeping the other leg in 90 degrees of knee flexion.The test was stopped when the contralateral foot touched the ground or when the participant broke 90 degrees of knee flexion.The OLST was repeated three times for each leg.GMFM:To assess standing and walking,running and jumping functions of the UCP group,the D and E dimensions of GMFM were utilized by a certificated physiotherapist.Each item was tested by three trials and the best trial was used.Pedobarography:The participants' plantar pressure was analyzed using pedobarography.For each participant, the pedobarography was calibrated before the assessment.During the pedobarographic analysis, the participants walked barefoot in 90 BPM cadence. Three steps were analyzed for each side.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: one leg standing test, gross motor function measurement, pedobarographic measurement
Description: OLST:During the OLST,the participants were asked to shoes off,place both hands on their hips and look at a point on the wall at eye level.A recording stopwatch was used to assess their standing duration on one leg while keeping the other leg in 90 degrees of knee flexion.The test was stopped when the contralateral foot touched the ground or when the participant broke 90 degrees of knee flexion.The OLST was repeated three times for each leg.GMFM:To assess standing and walking,running and jumping functions of the UCP group,the D and E dimensions of GMFM were utilized by a certificated physiotherapist.Each item was tested by three trials and the best trial was used.Pedobarography:The participants' plantar pressure was analyzed using pedobarography.For each participant, the pedobarography was calibrated before the assessment.During the pedobarographic analysis, the participants walked barefoot in 90 BPM cadence. Three steps were analyzed for each side.