Study: NCT03772249

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-HBVS
Description: DCR-HBVS is a synthetic ribonucleic acid interference (RNAi) drug that consists of a double-stranded oligonucleotide conjugated to N-acetyl-D-galactosamine (GalNAc) ligands. DCR-HBVS is a sterile solution of the siRNA (DCR-S219) at a concentration of 195 mg/mL in water for injection (WFI).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for DCR-HBVS
Description: Sterile 9% saline for injection.