TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03496545

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bromocriptine 5 MG
Description: Bromocriptine 5 mg every 4 hours PO/NG/FT

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen 650 MG
Description: Acetaminophen 650 mg every 4 hours PO/NG/FT for 48 hours

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetaminophen 650 MG
Description: Acetaminophen 650 mg every 4 hours PO/NG/FT for 48 hours
Study: NCT01847859

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound examination by nurses
Description: Focused examination of the pleural space and inferior vena cava.Reference method: Cardiologists performed ultrasound examinations.
Study: NCT02285218

Intervention type: OTHER
Intervention: serum blood sampling

Intervention type: OTHER
Intervention: serum blood sampling

Intervention type: OTHER
Intervention: serum blood sampling

Intervention type: OTHER
Intervention: serum blood sampling
Study: NCT00595959

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CLiRpath Photoablation System
Description: Use of CLiRpath Laser Catheter to improve vessel lumen diameter.
Study: NCT02540369

Intervention type: DRUG
Intervention: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Description: Administration by intravitreal injection.Muti-target Anti-VEGF agent. Dosing would be at physicians discretion.

Intervention type: DRUG
Intervention: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Description: Administration by intravitreal injection.Muti-target Anti-VEGF agent. Dosing would be at physicians discretion.
Study: NCT01051271

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: midazolam
Description: midazolam 1.5 mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: midazolam
Description: midazolam 1.5 mg
Study: NCT03849066

Intervention type: OTHER
Intervention: Parent-Reported Symptom Assessment
Description: As the basis for PRSA, the investigator will use the PediQuest Memorial Symptom Assessment Scale (PQ-MSAS), which is an adapted pediatric-specific version of the validated adult MSAS that assesses 28 physical and psychological symptoms over the past week. The study instrument is designed to be completed by a full-proxy parent, and 2 versions tailored for specific age groups are available (0-3, 3-18 years-old). Spanish versions are available for both instruments. The PQ-MSAS contains 28 symptom items, each with 4-point scores for domains of frequency, severity, and extent of bother. Based on these components, a global symptom score and individual symptom scores can be calculated (0-100 scale, with 100 being the worst).
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Zopiclone

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Alprazolam
Study: NCT03989427

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Flossing first and Brushing later (FB)
Description: Participants will follow Flossing first and Brushing later (FB) sequence for 2 weeks, and after 1 week wash out period, Brushing first and flossing later (BF) sequence for another 2 weeks.
Study: NCT02709187

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DP-R208
Description: Investigational product is prescribed to all of randomized subjects

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DP-R208
Description: Investigational product is prescribed to all of randomized subjects

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Candesartan cilexetil
Description: Investigational product is prescribed to all of randomized subjects

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Candesartan cilexetil
Description: Investigational product is prescribed to all of randomized subjects

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin
Description: Investigational product is prescribed to all of randomized subjects

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin
Description: Investigational product is prescribed to all of randomized subjects
Study: NCT00642369

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: quetiapine fumarate
Description: 600-750mg/day

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: haloperidol
Description: 6-40mg/day
Study: NCT03788447

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High end-tidal CO2
Description: maintaining of end-tidal CO2 with the range of 40-45 mmHg

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Low CO2 group
Description: maintaining of end-tidal CO2 with the range of 30-35 mmHg
Study: NCT04174300

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual Therapy
Description: 8 sessions of manual therapy (twice weekly) of 25 minutes including pressure maneuvers of about 4,5 N
Study: NCT00847665

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: repositioning
Description: Turning every 4 or 2 hours

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: repositioning
Description: Turning every 4 or 2 hours
Study: NCT00827281

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: D-cycloserine
Description: Single dosage prior to sessions 3, 4 \& 5

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single dosage prior to sessions 3, 4 \& 5
Study: NCT01189058

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: TMS can affect discrete functional ares of motor cortex offering non-invasive, painless mapping and modulation of motor systems. Inhibitory rTMS (1Hz)has been shown to safely lower motor cortex excitability in normal patients as well as adult and pediatric stroke patients. Dose is 20 minutes per day (1200 stimulations) x 10 days administered over the non-lesioned M1.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: TMS can affect discrete functional ares of motor cortex offering non-invasive, painless mapping and modulation of motor systems. Inhibitory rTMS (1Hz)has been shown to safely lower motor cortex excitability in normal patients as well as adult and pediatric stroke patients. Dose is 20 minutes per day (1200 stimulations) x 10 days administered over the non-lesioned M1.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Constraint-induced movement therapy (CIMT)
Description: CIMT uses gentle restraint of the fully functional upper extremity to promote functional gains in the affected upper extremity. CIMT is well established to be safe and is likely effective in children with hemiplegic cerebral palsy, many of whom have perinatal stroke as studied here. A custom-fitted, bivalved cast is applied and worn for \>90% of waking hours for the 2 weeks of active treatment according to protocol with daily assessments for comfort.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Constraint-induced movement therapy (CIMT)
Description: CIMT uses gentle restraint of the fully functional upper extremity to promote functional gains in the affected upper extremity. CIMT is well established to be safe and is likely effective in children with hemiplegic cerebral palsy, many of whom have perinatal stroke as studied here. A custom-fitted, bivalved cast is applied and worn for \>90% of waking hours for the 2 weeks of active treatment according to protocol with daily assessments for comfort.
Study: NCT01264172

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PCCP
Description: PCCP: an minimal-invasive surgery technique, in wich a special plate is pushed in position and fixed through 2 small approaches only (about 2 cm long)
Study: NCT01973647

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy for Insomnia
Description: Six weekly sessions of cognitive behavioral therapy for insomnia
Study: NCT01264172

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: DHS
Description: Conventional surgical treatment of proximal femur fracture including one longer approach from lateral
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil
Study: NCT01264172

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Osteosynthesis with nails
Description: Osteosynthesis with nails is a minimal-invasive surgery technique for proximal femur fractures.
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil
Study: NCT01973647

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy for Insomnia
Description: Six weekly sessions of cognitive behavioral therapy for insomnia

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COPD Education
Description: Six weekly sessions of COPD education

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COPD Education
Description: Six weekly sessions of COPD education

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Attention Control
Description: Six weekly sessions of non-sleep, non-COPD health education
Study: NCT03947944

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SMILE using vector planning
Description: The treatments of astigmatism were planned using either the manifest refraction (manifest refraction group) or the vector planning method (vector planning group). The surgery was performed with standardized techniques with triple centration technique using the 500-KHz VisuMax system (Carl Zeiss Meditec AG, Jena, Germany). The superior cap depth was set as 120 µm, and the length of the side cut was set to 2 mm. Once the anterior (upper) and posterior (lower) planes of the lenticule were defined, the anterior and posterior interfaces were dissected using a microspatula with a blunt circular tip and extracted with microforceps. The integrity of the lenticule was assessed subsequently. The treatment plan for the vector planning group involved a combination of refractive astigmatism with 60 % emphasis and corneal astigmatism with 40 % emphasis.
Study: NCT00340678

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan
Description: Treatment with losartan began at 50 mg daily, with the dose increasing to 100 mg daily after 1 week if symptomatic hypotension did not develop.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan
Description: Treatment with losartan began at 50 mg daily, with the dose increasing to 100 mg daily after 1 week if symptomatic hypotension did not develop.
Study: NCT05070117

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Study participants perform resistance/strength exercises 2-3 times per week for one hour, for one year.
Study: NCT02845245

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D printed plastic model prototype

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D CT scan
Study: NCT00340678

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Treatment with placebo corresponding to each dose of losartan.
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil
Study: NCT02845245

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 3D CT scan

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plain film radiographs

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Plain film radiographs
Study: NCT02014896

Intervention type: OTHER
Intervention: Biomarker blood draw
Description: Comparison of gene expression profiles using RNA isolated from whole blood.

Intervention type: OTHER
Intervention: Biomarker blood draw
Description: Comparison of gene expression profiles using RNA isolated from whole blood.
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil
Study: NCT01345578

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: human hepatocyte transplantation
Description: Transplantation of hepatocytes into the liver will be through the portal vein. The portal vein will be accessed transhepatically, by umbilical vein, or surgically by a peripheral mesenteric vein.~The subject will be evaluated de novo and if they are a candidate for orthotopic liver transplantation they will receive the transplant. Even if the subject receives the hepatocyte transplant and it does not work, they will be evaluated for orthotopic liver transplantation as if they never received the hepatocyte transplant.~If at 6 months we see an improvement in disease, we will recommend a re-transplantation with a goal of complete correction of disease and until the subject is no longer required to be a candidate for organ transplantation. Subjects will be re-evaluated every 6 months for re-transplantation. Subjects will remain on the waiting list for organ transplantation. Further radiation therapy will not be needed prior to re-transplantation.
Study: NCT02014896

Intervention type: OTHER
Intervention: Biomarker blood draw
Description: Comparison of gene expression profiles using RNA isolated from whole blood.
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Apple compote Donepezil
Study: NCT02570581

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Donepezil

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel
Study: NCT01345578

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Preparative Radiation Therapy
Description: Just prior to the hepatocyte transplant, a portion of the right hepatic lobe comprising between 35-50% of the entire liver volume will be irradiated to a dose of 7.5-10 Gy in a single fraction using a linear accelerator-based stereotactic radiosurgery system with intensity-modulated radiation therapy planning (IMRT).
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel
Study: NCT00627510

Intervention type: OTHER
Intervention: Routine psychiatric inpatient treatment
Description: Routine psychiatric inpatient treatment. This is not an interventional study.
Study: NCT04590352

Intervention type: PROCEDURE
Intervention: nasopharyngeal and throat swab
Description: diagnostic specimens via nasopharyngeal swab and throat swab were collected following the current standard operating procedures.
Study: NCT02570581

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Apple compote Clopidogrel
Study: NCT01601249

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Embryo selection based on polscope grading or morphology
Description: In the experimental arm embryo grading will be performed by polscope rather than conventional morphology, and the best embryo/s for transfer will be selected by this method.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Embryo selection based on polscope grading or morphology
Description: In the experimental arm embryo grading will be performed by polscope rather than conventional morphology, and the best embryo/s for transfer will be selected by this method.
Study: NCT01842256

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Telmisartan 80mg, S-amlodipine 5mg and Atorvastatin 40mg
Description: * 3 Tablets (telmisartan 80mg, amlodipine 5mg, atorvastatin 40mg each one),~* oral intake, once in a period~* over the period Ⅰ\&Ⅱ(crossover)
Study: NCT04590352

Intervention type: PROCEDURE
Intervention: collection of mucosal lining fluid
Description: MLF will be collected via nasal absorption at the inclusion visit by study staff and four more time points by the parents or by the children themselves. Nasal absorption is performed by maneuvering a strip of synthetic absorptive matrices (SAM) into the lumen of the nostril, avoiding rubbing against the nasal mucosa. The outside of the nose is then pressed with a finger to cause apposition of the SAM against the mucosa.

Intervention type: PROCEDURE
Intervention: blood collection via fingerprick
Description: Participants will be asked to wash their hands with soap and warm water. The procedure involves cleaning the ball of the fingertip with an alcohol swab, then using a sterile disposable lancet to pierce the skin (BD Microtainer Lancet or similar). The lancet is placed in a spring-loaded device, which propels the lancet a fixed distance (a few mm) into the skin when the trigger is pressed. Approximately 10-20 drops of blood (0.3 ml) will then be collected with a sterile capillary tube. The participant is given a cotton wool pad to mop up any extra blood, and an elastoplast-type bandage is placed over the finger if necessary. Fingerprick blood samples will only be collected from participants older than 6 months at 28-32 days after the first home visit (d0). Lancet length will be adjusted for age (2.0 mm for participants 8 years and older, 1.5 mm for participants older than 6 months and younger than 8 years).
Study: NCT01842256

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Telmisartan 80mg, S-amlodipine 5mg and Atorvastatin 40mg
Description: * 3 Tablets (telmisartan 80mg, amlodipine 5mg, atorvastatin 40mg each one),~* oral intake, once in a period~* over the period Ⅰ\&Ⅱ(crossover)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: atorvastatin 40mg
Description: * 1 Tablet (atorvastatin 40mg),~* oral intake, once in a period~* over the period Ⅰ\&Ⅱ(crossover)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: atorvastatin 40mg
Description: * 1 Tablet (atorvastatin 40mg),~* oral intake, once in a period~* over the period Ⅰ\&Ⅱ(crossover)
Study: NCT02781051

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Print-based education
Description: All subjects will be given a copy of Exercise for Health: An Exercise Guide for Breast Cancer Survivors. Topics covered within the book include benefits of exercise in breast cancer survivors; recommendations on type, duration, frequency and intensity of exercise; goal-setting; and advice on overcoming barriers.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fitbit
Description: Subjects will be provided with a commercially available activity monitor (i.e., Fitbit) and instructed to wear the device daily.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Living counseling
Description: The Active Living counseling program consists of 12 weekly group educational sessions, facilitated by project interventionists. These sessions will involve discussion of topics related to increasing physical activity, including: identifying and overcoming barriers, setting goals, and time management.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facility Access
Description: Subjects will have access to the exercise lab in the UT Southwestern Depression Center consisting of equipment for aerobic exercise (treadmills, stationary bikes, etc.).
Study: NCT03637972

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ventilated cigarettes only
Description: Participants given vouchers that are exchanged for ventilated cigarettes study cigarettes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unventilated cigarettes only
Description: Participants given vouchers that are exchanged for unventilated cigarettes study cigarettes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Access to Experimental Marketplace: Ventilated cigarettes + alternative nicotine delivery systems
Description: Participants given vouchers that are exchanged for ventilated cigarettes + alternative nicotine delivery systems cigarettes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Access to Experimental Marketplace: Unventilated cigarettes + ANDS
Description: Participants given vouchers that are exchanged for unventilated cigarettes + ANDS.
Study: NCT03263442

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thiamine
Description: 200 mg IV three times daily for seven days

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Normal saline IV three times daily for seven days