Study: NCT02143687

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate altitude sojourn
Description: Participants will travel from Zurich (490 m) to St. Moritz Salastrains (2048 m) and stay there for 2 days

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate altitude sojourn
Description: Participants will travel from Zurich (490 m) to St. Moritz Salastrains (2048 m) and stay there for 2 days

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Moderate altitude sojourn
Description: Participants will travel from Zurich (490 m) to St. Moritz Salastrains (2048 m) and stay there for 2 days

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Moderate altitude sojourn
Description: Participants will travel from Zurich (490 m) to St. Moritz Salastrains (2048 m) and stay there for 2 days

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low altitude sojourn
Description: Low altitude baseline evaluations will be performed during a stay at Zurich (490)

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low altitude sojourn
Description: Low altitude baseline evaluations will be performed during a stay at Zurich (490)

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Low altitude sojourn
Description: Low altitude baseline evaluations will be performed during a stay at Zurich (490)

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Low altitude sojourn
Description: Low altitude baseline evaluations will be performed during a stay at Zurich (490)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxygen
Description: Oxygen administration via a nasal cannula at a rate of 3 L/min during nights spent at 2048 m

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxygen
Description: Oxygen administration via a nasal cannula at a rate of 3 L/min during nights spent at 2048 m

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen
Description: Oxygen administration via a nasal cannula at a rate of 3 L/min during nights spent at 2048 m

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxygen
Description: Oxygen administration via a nasal cannula at a rate of 3 L/min during nights spent at 2048 m

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sham oxygen (room air)
Description: Sham oxygen (room air) administration via a nasal cannula at a rate of 3 L/min during nights at 490 m and 2048 m

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sham oxygen (room air)
Description: Sham oxygen (room air) administration via a nasal cannula at a rate of 3 L/min during nights at 490 m and 2048 m

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sham oxygen (room air)
Description: Sham oxygen (room air) administration via a nasal cannula at a rate of 3 L/min during nights at 490 m and 2048 m

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sham oxygen (room air)
Description: Sham oxygen (room air) administration via a nasal cannula at a rate of 3 L/min during nights at 490 m and 2048 m