TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT02064257

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Listening Project Protocol
Description: The intervention will consist of listening to computer-altered acoustic stimulation, designed to modulate the frequency band of vocal music passed to the participant. The frequency characteristics of the acoustic stimulation are selected to emphasize the relative importance of specific frequencies in conveying the information embedded in human speech. Modulation of the acoustic energy within the frequencies of human voice, similar to an exaggerated vocal prosody, are hypothesized to recruit and modulate the neural regulation of the middle ear muscles and to functionally reduce sound hypersensitivities and improve auditory processing.
Study: NCT03951662

Intervention type: OTHER
Intervention: Alcoholic Hepatitis Group
Description: Alcoholic hepatitis is defined as having a total bilirubin level \>3mg/dL and AST level\>50U/L

Intervention type: OTHER
Intervention: Heavy Drinking Controls without Hepatitis
Description: Normal levels of AST, ALT and total bilirubin and without evidence of cirrhosis or hepatosplenomegaly
Study: NCT00515619

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacosamide
Description: 50 mg and 100 mg tablets up to 800 mg/day as twice day (BID) dosing throughout the trial
Study: NCT02282514

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Hematopoietic Stem Cells
Description: The stem cells will be collected from patient's blood during mobilization. Then the patient will be given high dose chemotherapy in accordance with approved recommendations for use in conditioning regimens for stem cell transplant in autoimmune diseases. Autologous Hematopoietic Stem Cell Transplantation is to re-infuse immature cells that can re-establish blood production and patient's immune system.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: An alkylating agent which causes prevention of cell division by forming adducts with DNA

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesna
Description: Medication used to decrease the risk of hemorrhagic cystitis prophylaxis

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rATG
Description: A predominantly lymphocyte-specific immunosuppressive agent which contains antibodies specific to the antigens commonly found on the surface of T cells

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone
Description: Steroid

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: G-CSF
Description: Granulocyte-colony stimulating factor; a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituxan
Description: A chimeric monoclonal antibody used in the treatment of B cell non-Hodgkin's lymphoma, B cell leukemia, and some autoimmune disorders
Study: NCT01103752

Intervention type: OTHER
Intervention: no intervention, descriptive study
Description: no intervention, descriptive study
Study: NCT02379091

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Namilumab
Description: Namilumab subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Namilumab
Description: Namilumab subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Namilumab
Description: Namilumab subcutaneous injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Namilumab placebo-matching subcutaneous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Methotrexate tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Methotrexate tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Methotrexate tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methotrexate
Description: Methotrexate tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Folic/folinic acid
Description: Folic/folinic acid tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Folic/folinic acid
Description: Folic/folinic acid tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Folic/folinic acid
Description: Folic/folinic acid tablets

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Folic/folinic acid
Description: Folic/folinic acid tablets
Study: NCT02410226

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Double-space combined spinal-epidural anesthesia
Description: Epidural space identification in Lumbar 2-3 or 3-4 space using loss of resistance to air technique with 18-gauge Tuohy needle, then threading a 20-gauge multi-orifice epidural catheter 4-5 cm into the epidural space. Spinal anesthesia administration in an appropriate lower intervertebral space with intrathecal bupivacaine 12.5 mg and fentanyl 10 mcg through a 27-gauge spinal needle.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Double-space combined spinal-epidural anesthesia
Description: Epidural space identification in Lumbar 2-3 or 3-4 space using loss of resistance to air technique with 18-gauge Tuohy needle, then threading a 20-gauge multi-orifice epidural catheter 4-5 cm into the epidural space. Spinal anesthesia administration in an appropriate lower intervertebral space with intrathecal bupivacaine 12.5 mg and fentanyl 10 mcg through a 27-gauge spinal needle.

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Preprocedure spinal ultrasound
Description: Lumbar spinal ultrasound using the 2-5 MHz curved probe, performed in both the longitudinal and transverse planes for identification of the appropriate intervertebral spce, estimation of the depth to the epidural space, and noting the proper angle for subsequent needle insertion. Then skin markings relying on the ultrasound procedure are made identifying 2 intervertebral spaces.

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Sham ultrasound procedure
Description: Applying the ultrasound probe on the patient's back while the ultrasound machine is on the freeze position.Then skin markings relying on landmark palpation are made identifying 2 intervertebral spaces.
Study: NCT04015544

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Watermelon
Description: Pureed whole (100%) watermelon
Study: NCT03519633

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sugammadex
Description: Reversal of deep NMB

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neostigmine
Description: Reversal of moderate NMB
Study: NCT01698398

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Incremental pump speed of CF-LVAD.
Description: Peak oxygen consumption with fixed versus incremental pump speed.
Study: NCT03585751

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulpectomy for primary molars + triple antibiotic mix
Description: complete extirpation of infected pulp from primary molars. Following instrumentation and copious irrigation ,the root canals are filled with one of .Following instrumentation and copious irrigation ,the root canals are filled with a triple antibiotic mix mixed with a Carrier ( MP) as an obturating material

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpectomy for primary molars + 3mixstatin
Description: complete extirpation of infected pulp from primary molars. Following instrumentation and copious irrigation ,the root canals are filled with one of .Following instrumentation and copious irrigation ,the root canals are filled with 3mixstatin (triple antibiotic mix + simvastatin) as an obturating material mixed with a Carrier ( MP) as an obturating material

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpectomy for primary molars + simvastatin
Description: complete extirpation of infected pulp from primary molars. Following instrumentation and copious irrigation ,the root canals are filled with simvastatin as mixed with a Carrier ( MP) as an obturating material
Study: NCT04202107

Intervention type: OTHER
Intervention: Food Frequency Questionnaire
Description: Food frequency questionnaires (FFQs) are a common method for measuring dietary intake in large epidemiological studies, in particular in low literacy settings were diaries and food history would not be viable.

Intervention type: OTHER
Intervention: Food Frequency Questionnaire
Description: Food frequency questionnaires (FFQs) are a common method for measuring dietary intake in large epidemiological studies, in particular in low literacy settings were diaries and food history would not be viable.

Intervention type: OTHER
Intervention: 24 Hour food recall
Description: Standardized and validated approach of collecting all foods, beverages, and supplements consumed during the past 24 hours

Intervention type: OTHER
Intervention: 24 Hour food recall
Description: Standardized and validated approach of collecting all foods, beverages, and supplements consumed during the past 24 hours
Study: NCT03120897

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RAM sensor
Description: Rainbow Acoustic Monitoring sensor for measurement of respiratory rate
Study: NCT03710577

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yoga
Description: 1 session

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Quiet Rest
Description: 1 session
Study: NCT04258267

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Early mobilization
Description: Patients will wear an adduction sling to immobilize the shoulder during the first 4 weeks post-operative

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Delayed mobilization
Description: Patients will wear an abduction sling to immobilize the shoulder during the first 4 weeks post-operative, followed by an adduction sling for 2 weeks.
Study: NCT04382352

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Humanized Anti-HER2 Monoclonal Antibody Compound for Injection .R&D code: B002.
Description: Usage: intravenous infusion; B002, doses 2, 6, 12, 16, 20 mg / kg, intravenous drip. The infusion time was 120 ± 10 minutes for the first time; if the patient was tolerated, the follow-up time was adjusted to 60 ± 10 minutes. Pre-treatment was performed using phenergan (25 mg, intramuscular) within 30 minutes prior to each study drug infusion. The dosing cycle is administered once every 3 weeks for one cycle and can be administered continuously until the disease progresses or is intolerable.
Study: NCT04773535

Intervention type: DEVICE
Intervention: 3D Motion analysis
Description: Motion analysis using DyCare® Lynx system with inertial based sensors as well as an optoelectronic motion analysis system based on infrared cameras (11x Vicon infrared high speed cameras)
Study: NCT02173899

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: varicella-1
Description: Give the second varicella vaccine (a single 0.5 ml) and get blood samples at 0, 35-42 day

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: varicella-3
Description: Give the second varicella vaccine (a single 0.5 ml) and get blood samples at 0, 35-42 day

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: varicella-5
Description: Give the second varicella vaccine (a single 0.5 ml) and get blood samples at 0, 35-42 day
Study: NCT00332176

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Celgosivir
Description: 400mg qd + standard of care for 12 weeks

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Celgosivir
Description: 600mg qd + standard of care for 12 weeks

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Peginterferon alfa 2b + ribavirin
Description: Standard of care for 12 weeks
Study: NCT03237455

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic spine x-rays+whole spine MRI
Description: PA radiographs of the thoracic spine and MRI of the whole spine and sacroiliac joints

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Thoracic spine x-rays+whole spine MRI
Description: PA radiographs of the thoracic spine and MRI of the whole spine and sacroiliac joints

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: blood tests
Description: blood chemistry including total cholesterol, LDL HDL, CBC, HbA1C, fasting glucose, TG, and insulin levels, HLA-B27, 2 vials of frozen serum for future studies.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: blood tests
Description: blood chemistry including total cholesterol, LDL HDL, CBC, HbA1C, fasting glucose, TG, and insulin levels, HLA-B27, 2 vials of frozen serum for future studies.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: constitutional and demographic data collection
Description: demographics, concomitant diseases (in particular type 2 DM, hypertension, hyperlipidemia) concomitant medications, height and weight (BMI), waist circumference

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: constitutional and demographic data collection
Description: demographics, concomitant diseases (in particular type 2 DM, hypertension, hyperlipidemia) concomitant medications, height and weight (BMI), waist circumference
Study: NCT02716480

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobility coaching
Description: The intensive follow-up for the patients of Mobility Coaching  arm will consist on a monthly remote coaching of 20 to 30 minutes led by a Mobility coach. The web platform allows self-administration of a questionnaire to establish patient's diagnosis of mobility to enable personalized coaching. The web platform can also track the parameters collected by connected devices (pedometer and connected scale), organize appointments with patients and ensure the traceability of exchanges with patients. A smartphone application tracks different modes of locomotion used.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diet coaching
Description: The intensive follow-up for the patients of Diet Coaching  arm will consist on a monthly remote coaching of 20 to 30 minutes led by dietitian trained in the care of patients undergoing bariatric surgery.
Study: NCT02641288

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine irrigation
Description: Using a standard irrigation device (no specific device is being used), 300 mg total of ropivacaine in 200ml normal saline will be instilled into the abdomen after surgical dissection, just before abdominal wall closure. Under direct visualization, the solution is delivered over the oesophageal hiatus, over both anastomoses and in both subdiaphragmatic spaces.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline irrigation
Description: Using a standard irrigation device (no specific device is being used), 200ml normal saline will be instilled into the abdomen after surgical dissection, just before abdominal wall closure.
Study: NCT04657393

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mechanical ventilation
Description: change of ventilation frequency

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mechanical ventilation
Description: change of ventilation frequency
Study: NCT00518765

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aliskiren

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aliskiren plus placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aliskiren

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aliskiren plus placebo
Study: NCT00654771

Intervention type: OTHER
Intervention: urine collection
Description: clean catch urine collection and catheterized urine collection
Study: NCT02447003

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion of 200 mg.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion of 200 mg.
Study: NCT02747836

Intervention type: OTHER
Intervention: Ultrasound of the wrist
Description: using sound waves to create images capturing the movement of the SSCT and flexor tendon and transformation of the median nerve in the wrist

Intervention type: OTHER
Intervention: Ultrasound of the wrist
Description: using sound waves to create images capturing the movement of the SSCT and flexor tendon and transformation of the median nerve in the wrist
Study: NCT03739723

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resource allocation to improve surgical learning environments
Description: If a hospital/program is assigned to the intervention arm, they will receive numerous resources including a program-specific learning environment and resident well-being report, a Wellness Toolkit, coaching webinars, and in-person/virtual conferences to help improve their surgery learning environment and residents' well-being.
Study: NCT01120964

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravenous L-Citrulline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of Intravenous L-Citrulline
Description: Placebo of intravenous L-Citrulline given at the same prescribed times as L-Citrullne Drug
Study: NCT01003769

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: R-(-)-Gossypol Acetic Acid
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laboratory Biomarker Analysis
Description: Correlative studies
Study: NCT04161157

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pathways
Description: Goal-setting intervention to help patients identify personal values, value-consistent goals, and ways to pursue goals and address goal obstacles. Although potential refinements may occur based on aim 1 (refining procedures and content with 6 patients), Pathways is designed to consist primarily of 2 in-person sessions (\~30-60 minutes) delivered when patients are in clinic for cancer treatment, with supporting phone calls and contact in between sessions.
Study: NCT04606602

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SLN360
Description: SLN360 for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sodium chloride for subcutaneous (s.c.) injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sodium chloride for subcutaneous (s.c.) injection
Study: NCT01393392

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive, tailored intervention
Description: Eight, 45 minute counseling sessions, tailored to the individual and based on the Information-Motivation-Behavioral Skills model of behavior change. Incorporates motivational interviewing, education, cognitive-behavioral skills training. 12 week course of nicotine replacement patches provided. Nicotine lozenges also provided.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: NJ Quitline Referral
Description: Participants will receive a facilitated referral to the NJ Quitline (i.e. fax to quit).
Study: NCT04302077

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: virtual doctor visit
Description: interactive live-video feed at home through EPIC

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care doctor's visit
Description: In person visit as per standard of care
Study: NCT06212128

Intervention type: COMBINATION_PRODUCT
Intervention: RAPIDO TNT
Description: neoadjuvant therapy per RAPIDO protocol (Patients under RAPIDO group underwent 25Gy/5 sessions of short course radiotherapy followed by 6 cycles of neoadjuvant XELOX similar to that of the RAPIDO trial protocol)

Intervention type: COMBINATION_PRODUCT
Intervention: LCRT
Description: LCRT group underwent conventional 50Gy/25-28 sessions of long course radiotherapy with concurrent oral capecitabine
Study: NCT02840461

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin Cream, 1%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ivermectin Cream, 1%

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo/Vehicle cream
Study: NCT03810924

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trier Social Stress Test
Description: Test to induce high levels of acute social stress, including actors and a faked exam situation

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ergometer
Description: Riding ergometer

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Barlab-Exposure
Description: Participants are exposed to a bar situation with different sorts of alcohol available. They sniff at water and at one alcoholic drink.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Barlab-Exposure
Description: Participants are exposed to a bar situation with different sorts of alcohol available. They sniff at water and at one alcoholic drink.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Barlab-Exposure
Description: Participants are exposed to a bar situation with different sorts of alcohol available. They sniff at water and at one alcoholic drink.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Reading Newspaper
Description: Participants read newspaper
Study: NCT00735488

Intervention type: OTHER
Intervention: Observational
Description: Summary of data

Intervention type: OTHER
Intervention: Observational
Description: Summary of data
Study: NCT02773316

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MR902

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MR902

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IR morphine sulphate
Study: NCT01582269

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY2157299 monohydrate
Description: Orally administered as tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY2157299 monohydrate
Description: Orally administered as tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lomustine
Description: Orally administered as capsules

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lomustine
Description: Orally administered as capsules

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Orally administered as tablets