Study: NCT01768910

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI
Description: 2 measurements using functional magnetic resonance imaging in a 3T scanner

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI
Description: 2 measurements using functional magnetic resonance imaging in a 3T scanner

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI
Description: 2 measurements using functional magnetic resonance imaging in a 3T scanner

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI
Description: 2 measurements using functional magnetic resonance imaging in a 3T scanner

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI
Description: 2 measurements using functional magnetic resonance imaging in a 3T scanner

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder filling
Description: Repetitive retrograde bladder filling via transurethral catheter with different filling volumes using body warm saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder filling
Description: Repetitive retrograde bladder filling via transurethral catheter with different filling volumes using body warm saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder filling
Description: Repetitive retrograde bladder filling via transurethral catheter with different filling volumes using body warm saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder filling
Description: Repetitive retrograde bladder filling via transurethral catheter with different filling volumes using body warm saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder filling
Description: Repetitive retrograde bladder filling via transurethral catheter with different filling volumes using body warm saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder cooling
Description: Retrograde bladder filling via transurethral catheter with 4-8°C saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder cooling
Description: Retrograde bladder filling via transurethral catheter with 4-8°C saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder cooling
Description: Retrograde bladder filling via transurethral catheter with 4-8°C saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder cooling
Description: Retrograde bladder filling via transurethral catheter with 4-8°C saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bladder cooling
Description: Retrograde bladder filling via transurethral catheter with 4-8°C saline during each of the fMRI measurements.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: additional post-treatment fMRI scan
Description: Should NNOAB or SCI patients receive a study independent OAB therapy by their treating physician after the 2nd fMRI scan, they will be invited for an additional third fMRI scan.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: additional post-treatment fMRI scan
Description: Should NNOAB or SCI patients receive a study independent OAB therapy by their treating physician after the 2nd fMRI scan, they will be invited for an additional third fMRI scan.