Study: NCT03534895

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam Injectable Solution
Description: intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam Injectable Solution
Description: intravenous

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: intravenous

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal saline
Description: intravenous

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal saline
Description: intravenous

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Spinal anesthesia
Description: 8mg of heavy bupivacaine 0.5% injected in the subarachnoid space, during lateral decubitus

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spinal anesthesia
Description: 8mg of heavy bupivacaine 0.5% injected in the subarachnoid space, during lateral decubitus

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spinal anesthesia
Description: 8mg of heavy bupivacaine 0.5% injected in the subarachnoid space, during lateral decubitus

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Surgery
Description: Open inguinal hernia repair, varicose vein stripping, knee arthroscopy or hallux valgus surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Open inguinal hernia repair, varicose vein stripping, knee arthroscopy or hallux valgus surgery

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Open inguinal hernia repair, varicose vein stripping, knee arthroscopy or hallux valgus surgery

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Postoperative analgesia
Description: IV acetaminophen 1g + IV ketorolac 30mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Postoperative analgesia
Description: IV acetaminophen 1g + IV ketorolac 30mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Postoperative analgesia
Description: IV acetaminophen 1g + IV ketorolac 30mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rescue analgesia
Description: Tramadol 2mg/Kg IV in 100mL of normal saline, if pain NRS\>3.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rescue analgesia
Description: Tramadol 2mg/Kg IV in 100mL of normal saline, if pain NRS\>3.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rescue analgesia
Description: Tramadol 2mg/Kg IV in 100mL of normal saline, if pain NRS\>3.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Wound infiltration
Description: Wound infiltration with 10mL of ropivacaine 0.75%, in open inguinal hernia repair

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Wound infiltration
Description: Wound infiltration with 10mL of ropivacaine 0.75%, in open inguinal hernia repair

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Wound infiltration
Description: Wound infiltration with 10mL of ropivacaine 0.75%, in open inguinal hernia repair

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Analgesia at home
Description: Oral acetaminophen 1g 6/6h + ibuprofen 400mg 8/8h (+ rescue analgesia with tramadol 50mg 6/6h)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Analgesia at home
Description: Oral acetaminophen 1g 6/6h + ibuprofen 400mg 8/8h (+ rescue analgesia with tramadol 50mg 6/6h)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Analgesia at home
Description: Oral acetaminophen 1g 6/6h + ibuprofen 400mg 8/8h (+ rescue analgesia with tramadol 50mg 6/6h)