TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03776721

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Liposuction
Description: Liposuction is performed on the abdomen or thighs.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Liposuction
Description: Liposuction is performed on the abdomen or thighs.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fat graft
Description: 30mL harvested lipoaspirate is injected at the affected axillary site.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Sham graf (Saline injection)
Description: 30mL saline is injected at the affected axillary site.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Stem cell injection
Description: 4mL stem cell suspension injected at the affected axillary site.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Saline injection
Description: 4mL saline injected at the affected axillary site.
Study: NCT03045159

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strong Families Strong Forces
Description: Parenting program

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Strong Parents
Description: self-care program
Study: NCT01401049

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fospropofol
Description: To compare the incidence and intensity of pain on injection that is caused by propofol (lipid emulsion) versus the test drug fospropofol. A third arm will also be included using a current standard (propofol plus lidocaine) as a methodological control.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol/Lidocaine
Description: We plan to assess the incidence and intensity of pain on injection that is caused by propofol (lipid emulsion).
Study: NCT03370874

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ALLO-ASC-DFU
Description: Application of ALLO-ASC-DFU sheet to diabetic foot ulcer

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle sheet
Description: Application of Vehicle sheet to diabetic foot ulcer
Study: NCT03535675

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Muscadine Plus
Description: Ellagic acid inhibits DNA Methyltransferase. DNA Methyltransferases (DNMTs) are a family of enzymes that regulate chromatin methylation and use S-adenosyl methionine (SAM) as the methyl donor. Ellagic acid's metabolite, urolithin-A inhibits the protein complex nuclear factor kappa-light-enhancer of activated B-cells (NFkB), potentially leading to increased rates of apoptosis and decreases in cancer cell proliferation. Extracts from Vitis rotundifolia have shown inhibition of the phosphatidylinositol 3-kinase-Akt pathway.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebos
Description: The placebo capsules are rice flour that will be placed in white opaque capsules identical to the ones used for MPX.
Study: NCT01884662

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual walking
Description: As in mirror therapy for amputee phantom pain, there is evidence that neuropathic SCI pain responds to images of the person with SCI's legs walking; we achieve this via a virtual reality approach where the subject perceives it is his/her legs walking.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Wheeling tape
Description: This control condition mirrors the experimental condition in all respects except it shows still legs in a wheelchair traversing the same path as the virtual walking condition
Study: NCT01409590

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Exercise program
Description: Homogenous exercise program in local fitness centers

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Diet
Description: Weigh loss diet program prescribed by a professional nutritionist
Study: NCT02616081

Intervention type: OTHER
Intervention: Surgery
Description: Bladder surgery is a standard of care.

Intervention type: OTHER
Intervention: Voiding
Description: Voiding spontaneously is a standard of care.
Study: NCT01626521

Intervention type: OTHER
Intervention: CT pulmonary angio, blood tests
Description: CT pulmonary angiography to determine PE and laboratory blood tests to determine prothrombin fragments F1+2 in blood of COPD patients
Study: NCT04813315

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kendall exercise
Description: consist of stretch of pectoralis major and neck extensor strengthening of deep neck flexors and scapular retractor

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gong's mobilization
Description: it is combination of glide along the facet joint and concurrent movement of cervical spine
Study: NCT03863093

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electro Medical Systems AIRFLOW®
Description: An erythritol powder will be used by Electro Medical Systems AIRFLOW® and then Electro Medical Systems Piezo will be used for supra- and subgingival ultrasonic instrumentation

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electro Medical Systems Piezo
Description: Electro Medical Systems Piezo will be used for supra- and subgingival ultrasonic instrumentation

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electro Medical Systems Piezo
Description: Electro Medical Systems Piezo will be used for supra- and subgingival ultrasonic instrumentation
Study: NCT01227759

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug containing the active ingredient
Description: The topical application is performed once daily during a 12-day treatment.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo containing no active ingredient
Study: NCT03236285

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-intensity interval exercise training in the fed state
Description: High-intensity interval exercise training in the fed state

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Continous exercise training in the fed state
Description: Continous exercise training in the fed state

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-intensity interval exercise training in the fasting state
Description: High-intensity interval exercise training in the fasting state

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Continous exercise training in the fasting state
Description: Continous exercise training in the fasting state
Study: NCT02477150

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Zostavax
Description: Vaccination of a zoster vaccine (Zostavax)

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo administration
Study: NCT01496248

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Korean Red Ginseng
Description: 100% of the past psychiatric medication dose will be maintained during 8 week study period. Korean Red ginseng will be started with 2g/day and then maintained using flexible dosing of 2-3g/day during the study period.
Study: NCT02234726

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early Childhood Development Program
Description: A cadre of community-based health workers, Child Development Agents (CDAs), have four main tasks and responsibilities: 1) biweekly screening and management (including referral) of acute malnutrition in children; 2) encouragement of caregivers to utilize routine care services for children; 3) screening for symptoms of acute diseases and referral for diagnosis and treatment; and 4) organization and mentoring of weekly meetings for caregivers to discuss parenting issues and promote early childhood cognitive stimulation.~Amendment: during second year extension, CDAs are responsible for organizing and mentoring biweekly (i.e., fortnightly) caregiver meetings. They no longer conduct household visits.
Study: NCT02559648

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Denosumab
Description: Patients will be randomly assigned, in a 1:1 fashion, to the two therapeutic arms (Group A, Group B, respectively), upon enrollment in the study.~The effect of denosumab on lumbar spine BMD (bone mineral density) in patients with Thalassemia Major and Osteoporosis as compared with control at 12 months will be evaluated.
Study: NCT02974036

Intervention type: OTHER
Intervention: Patient education for osteoarthritis
Description: Group sessions and optional supervised exercise.
Study: NCT02400671

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMS messaging

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMS messaging
Study: NCT03880773

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Stapler
Description: for transection of the pancreas and pancreatic stump treatment

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ultrasonic shears
Description: for transection of the pancreas and pancreatic stump treatment
Study: NCT02559648

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will be randomly assigned, in a 1:1 fashion, to the two therapeutic arms (Group A, Group B, respectively), upon enrollment in the study.~The effect of denosumab on lumbar spine BMD (bone mineral density) in patients with Thalassemia Major and Osteoporosis as compared with control at 12 months will be evaluated.
Study: NCT05542459

Intervention type: DRUG
Intervention: Biologics
Description: Infliximab, adalimumab, vedolizumab, ustekinumab, and other biologics approved for IBD

Intervention type: DRUG
Intervention: Biologics
Description: Infliximab, adalimumab, vedolizumab, ustekinumab, and other biologics approved for IBD
Study: NCT03037866

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LifeSkills Training for College
Description: The intervention will consist of e-learning modules (self-guided) and small-group sessions (facilitator led). The intervention is designed for new college students and is aimed at providing tools and strategies to help them maximize opportunities and adeptly handle the challenges ahead. The intervention will teach them the knowledge and skills needed to stay safe from problems that are prevalent among new students on college campuses, such as alcohol and drug abuse and sexual violence.
Study: NCT03087175

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MGuard stent
Description: MGuard micronet mesh-covered stent in treatment of STE and NSTE-ACS

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Drug eluting stent and bare metal stent
Description: Drug eluting stent and bare metal stent in treatment of STE and NSTE-ACS For example, Resolute Onyx
Study: NCT02129712

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive training
Study: NCT03830086

Intervention type: DRUG
Group type: OTHER
Intervention: Bupivacaine
Description: Used for regional anesthesia (spinal or combined spinal-epidural anesthesia) for gynecological laparoscopic procedures, together with Sufentanil
Study: NCT02129712

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Cognitive training
Study: NCT04653974

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Needle-free injection
Description: This study was performed among children aged 4-11 years who required dental treatment and were treated at the Department of Pedodontics, Faculty of Dentistry, Gaziosmanpasa University. A total of 70 patients were evaluated in accordance with the exclusion criteria and 56 children (31 girls and 25 boys) were included in this study. Children who needed dental treatment were randomly divided into two groups. All dental injections were administered by the same operator (MB), a pediatric dentist with two years of experience in using the Comfort-In system.~In both groups, the children were asked to rate their pain intensity by choosing the closest statement on the Wong-Baker Pain Scale at three time points: immediately after injection (Pain 1), during treatment (Pain 2), and at the end of the treatment (Pain 3).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Needle-free injection
Description: This study was performed among children aged 4-11 years who required dental treatment and were treated at the Department of Pedodontics, Faculty of Dentistry, Gaziosmanpasa University. A total of 70 patients were evaluated in accordance with the exclusion criteria and 56 children (31 girls and 25 boys) were included in this study. Children who needed dental treatment were randomly divided into two groups. All dental injections were administered by the same operator (MB), a pediatric dentist with two years of experience in using the Comfort-In system.~In both groups, the children were asked to rate their pain intensity by choosing the closest statement on the Wong-Baker Pain Scale at three time points: immediately after injection (Pain 1), during treatment (Pain 2), and at the end of the treatment (Pain 3).
Study: NCT01119287

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone 0.1% ophthalmic suspension
Description: Maxidex
Study: NCT04688866

Intervention type: OTHER
Intervention: Sequencing
Description: This is an observational study, since the assignment of the medical intervention (e.g. cerclage or pessary) is not at the discretion of the investigator. However, cervical samples collected from both groups are subjected to amplicon sequencing for taxonomic classification of microorganisms.
Study: NCT01119287

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olopatadine hydrochloride 0.1% ophthalmic solution
Description: Patanol

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Inactive ingredients, used as placebo
Description: Tears Naturale II
Study: NCT04731948

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Folic Acid
Description: 400µg Folic Acid per day for 16 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Folic Acid
Description: 400µg Folic Acid per day for 16 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Folic Acid
Description: 400µg Folic Acid per day for 16 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Folic Acid
Description: 400µg Folic Acid per day for 16 weeks
Study: NCT04957004

Intervention type: DEVICE
Intervention: CPAP
Description: CPAP ventilator was worn at nigh
Study: NCT03172442

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vacuum plate
Description: Vacuum plate with two hooks between lateral incisor and canine in each side will be applied on the lower arch.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rapid maxillary expander
Description: Rapid maxillary expander will be applied in the maxilla to disarticulate maxillary sutures to allow more efficient forward protraction of the maxilla.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Class III elastics
Description: Class III elastic traction from upper first molar to the hook in both side will be applied.
Study: NCT01424943

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Stepping Stones Triple P
Description: 10-12 session manualized intervention delivered in client homes
Study: NCT04636229

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Amniotic Suspension Allograft
Description: This investigational product is a cryopreserved product derived from human amnion and cells from the amniotic fluid.
Study: NCT01687582

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLP-1 analog
Description: GLP-1 analog treatment
Study: NCT01424943

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stepping Stones Triple P
Description: 10-12 session manualized intervention delivered in client homes

Intervention type: OTHER
Group type: OTHER
Intervention: BabyNet Services As usual
Description: BabyNet services as usual based on IFSP
Study: NCT04130412

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: open release
Description: Open release of lateral retinaculae
Study: NCT03903744

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cardioneuroablation
Description: The electroanatomical map of the right (RA) and left (LA) atrium will be created and anatomically-based ablation of GP will be performed. Ablation in the RA is started from the supero-posterior area (superior right atrial GP), to the middle-posterior area (posterior right atrial GP). In the LA, ablation is started at the site of the anterior right GP and is continued downwards along the anterior part of a common vestibulum of the right pulmonary veins (PV), opposite to the right-sided ablation lesions. Finally, area of right inferior GP, close to the RIPV is ablated under intracardiac echocardiography control. Using this technique, GP's located close to the left PV are not ablated. We use a pure anatomic approach without identification of GP.
Study: NCT03601208

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Mitra
Description: When the patients have their bloods done through venepuncture, an additional 5-10mls will be taken (one EDTA bottle for tacrolimus and one serum bottle for creatinine; and two Mitra VAMs). Patients will also have a fingerprick test and 20 microlitres of blood taken using Mitra volumetric absorptive microsampling (VAMs)
Study: NCT03912610

Intervention type: DIAGNOSTIC_TEST
Intervention: Functional magnetic resonance examination
Description: Functional magnetic resonance examination by a Ultra high field magnetic resonance instrument named MAGNATOM 7T.

Intervention type: DIAGNOSTIC_TEST
Intervention: Functional magnetic resonance examination
Description: Functional magnetic resonance examination by a Ultra high field magnetic resonance instrument named MAGNATOM 7T.
Study: NCT00537472

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low dose bupivicaine in spinal anesthetic
Description: Bupivacaine 9 mg intrathecal single shot injection at start of surgery

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard dose bupivacaine in spinal anesthetic
Description: Bupivacaine 13 mg intrathecal single shot injection at start of surgery
Study: NCT01175343

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gamma-Secretase Inhibitor RO4929097
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laboratory Biomarker Analysis
Description: Correlative studies
Study: NCT02398526

Intervention type: DRUG
Intervention: Radium-223 dichloride, (Xofigo, BAY88-8223)
Description: Dosage and treatment duration according to the decision of the treating physician
Study: NCT03273907

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CyPass Micro-Stent implanted with CyPass 241-S applier
Description: CyPass System (Model 241-S) consists of the CyPass Micro-Stent contained in a loading device (loader) and the CyPass applier.The CyPass Micro-Stent is an implantable medical device intended for long term use.
Study: NCT04636229

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo is 0.9% normal saline: 4 mL to be injected IA.
Study: NCT04446000

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CSL730
Description: solution for injection and infusion
Study: NCT02041091

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tabalumab Auto-Injector
Description: Administered SC

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tabalumab Prefilled Syringe
Description: Administered SC
Study: NCT04553861

Intervention type: DEVICE
Intervention: Ambulatory blood pressure monitoring
Description: Every 30 minutes from 7 AM to 10 PM and every 1 hour from 10 PM to 7 AM
Study: NCT04446000

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CSL730
Description: solution for injection and infusion

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CSL730
Description: solution for injection and infusion
Study: NCT04731948

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: 2 µg Vitamin B12
Description: 2 µg Vitamin B12 per day for 16 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: 10 µg Vitamin B12
Description: 10 µg Vitamin B12 per day for 16 weeks

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: 50 µg Vitamin B12
Description: 50 µg Vitamin B12 per day for 16 weeks
Study: NCT04589520

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HeartBot App
Description: HeartBot is an app designed to enable people 14 years and older to use relaxation tools offered by Heartfulness to deal with daily stress and anxiety in a healthy, productive manner.
Study: NCT04626011

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tooth extractions
Description: After blood collection tests, Periodontal analysis, Orthopantomography and Anamnestic record each group will receive a full mouth disinfection and needed extractions.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tooth extractions
Description: After blood collection tests, Periodontal analysis, Orthopantomography and Anamnestic record each group will receive a full mouth disinfection and needed extractions.
Study: NCT01969461

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Enhancement Therapy (MET)
Description: The 4-session MET intervention will address alcohol use and HIV medication (ART) adherence. Sessions will be delivered in the clinic or the home by a CHW (outreach worker, etc) already providing services in the clinic. In sessions 1 and 2 (each behavior will get its own session), CHW will elicit the client's view of the problem using MI techniques, building motivation for change by eliciting and reinforcing change talk. The CHW will deliver feedback and discuss the consideration of a behavior change plan option, and the client sets the change plan goal and consolidates commitment. In the last two sessions, the CHW will review the change plan, continue to elicit and reinforce change talk, problem-solve barriers, consolidate commitment, and consider strategies to maintain behavior change.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Motivational Enhancement Therapy (MET)
Description: The 4-session MET intervention will address alcohol use and HIV medication (ART) adherence. Sessions will be delivered in the clinic or the home by a CHW (outreach worker, etc) already providing services in the clinic. In sessions 1 and 2 (each behavior will get its own session), CHW will elicit the client's view of the problem using MI techniques, building motivation for change by eliciting and reinforcing change talk. The CHW will deliver feedback and discuss the consideration of a behavior change plan option, and the client sets the change plan goal and consolidates commitment. In the last two sessions, the CHW will review the change plan, continue to elicit and reinforce change talk, problem-solve barriers, consolidate commitment, and consider strategies to maintain behavior change.
Study: NCT04459897

Intervention type: OTHER
Intervention: Evaluation of epithelioid and gigantocellular granulomas within the hepatic parenchyma by histopathology approach.
Description: : Retrospective histopathology review done by an expert of histopathology analysis (DAPI cell labeling). Analysis of the percentage of epithelioid cells and the percentage of gigantocellular granulomas in hepatic parenchyma of patient diagnosed for Hepatitis Granulomatous