Study: NCT00673309

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stable Isotope Infusion study
Description: Stable isotope infusion study to be done following each surgery. Tagged isotopes to assess uptake into blood and tissues. Includes collection of blood and tissues (muscle)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin High Dose
Description: Insulin IV administered continuously throughout hospitalization until wounds are 95% healed.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: oxandrolone
Description: Oxandrolone given daily throughout hospitalization until 95% wound healing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Propranolol to be given daily throughout hospitalization until 95% wound healing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Growth Hormone
Description: Recombinant Human Growth hormone to be administered daily until 95% wound healing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Low Dose
Description: Insulin administered IV until 95% wound healing

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IGF-1/IGFBP-3
Description: Insulin Like Growth Factor-1/Insulin like Growth Factor Binding Protein 3 administered until 95% wound healing

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Itraconazole administered until 95% wound healing

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Growth Hormone and Propranolol
Description: Growth Hormone and Propranolol given until 95% wound healing

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxandrolone and Propranolol
Description: Oxandrolone and Propranolol

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo or Control
Description: Administration of Placebo or Control until 95% wound healing