TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04706364

Intervention type: BEHAVIORAL
Intervention: Neuropsychological Testing
Description: Includes an IQ test, Autism Diagnostic Observation Schedule-2 (ADOS-2), and Autism Diagnostic Interview-Revised (ADI-R) assessments.

Intervention type: BEHAVIORAL
Intervention: Neuropsychological Testing
Description: Includes an IQ test, Autism Diagnostic Observation Schedule-2 (ADOS-2), and Autism Diagnostic Interview-Revised (ADI-R) assessments.

Intervention type: GENETIC
Intervention: (Optional) Saliva Collection
Description: The sample is to test for genes (BDNF/APOE/COMT) that everyone has, but people have different varieties of these genes.~Genetic testing is funded by Boston Children's Hospital.

Intervention type: GENETIC
Intervention: (Optional) Saliva Collection
Description: The sample is to test for genes (BDNF/APOE/COMT) that everyone has, but people have different varieties of these genes.~Genetic testing is funded by Boston Children's Hospital.

Intervention type: DEVICE
Intervention: Sensory Testing
Description: Three different tests will be completed:~the tactile prepulse inhibition test (PPI) texture perception indentation testing (Mechanical Detection Threshold).~Investigators will also apply mild electrical stimulation to the median nerve of the hand (on the wrist).~The second sensory visit will be another version of the PPI testing involving hearing and sound.

Intervention type: DEVICE
Intervention: Sensory Testing
Description: Three different tests will be completed:~the tactile prepulse inhibition test (PPI) texture perception indentation testing (Mechanical Detection Threshold).~Investigators will also apply mild electrical stimulation to the median nerve of the hand (on the wrist).~The second sensory visit will be another version of the PPI testing involving hearing and sound.

Intervention type: DEVICE
Intervention: Electroencephalogram (EEG)
Description: A cap will be placed on the participants head that will be filled with electrodes (small discs). The EEG will allow investigators to measure how the brain reacts to the sensory testing.

Intervention type: DEVICE
Intervention: Electroencephalogram (EEG)
Description: A cap will be placed on the participants head that will be filled with electrodes (small discs). The EEG will allow investigators to measure how the brain reacts to the sensory testing.

Intervention type: DEVICE
Intervention: Transcranial Magnetic Stimulation
Description: Single pulses of TMS, as well as PAS (a second type of TMS), will be applied to the cortex.~There will be two - four identical TMS testing visits.

Intervention type: DEVICE
Intervention: Transcranial Magnetic Stimulation
Description: Single pulses of TMS, as well as PAS (a second type of TMS), will be applied to the cortex.~There will be two - four identical TMS testing visits.
Study: NCT03572920

Intervention type: DEVICE
Intervention: Objective sleep evaluation by actigraphy
Description: Each subject will wear a wrist activity monitor (actigraphy) to detect his/her sleep behaviour during hospitalization.

Intervention type: OTHER
Intervention: Pittsburgh Sleep Quality Index (PSQI)
Description: Each subject will fill twice the Pittsburgh Sleep Quality Index (PSQI), before hospitalization and after the 10th day, to evaluate his/her subjective sleep quality.
Study: NCT04162249

Intervention type: OTHER
Intervention: Conventional LSI/AI-guided pulmonary veins ablation.
Description: Conventional (low-power and long-duration) radiofrequency application.

Intervention type: OTHER
Intervention: High-power pulmonary veins ablation.
Description: Experimental (high-power and short-duration) radiofrequency application.

Intervention type: OTHER
Intervention: Esophageal temperature monitoring
Description: Two probes were simultaneously used: a deflectable one and a non-deflectable one.

Intervention type: DIAGNOSTIC_TEST
Intervention: Esophageal endoscopy
Description: Esophageal endoscopy for acute detection of esophageal thermal lesions \<72 hours after ablation.

Intervention type: DIAGNOSTIC_TEST
Intervention: Esophageal endoscopy
Description: Esophageal endoscopy for acute detection of esophageal thermal lesions \<72 hours after ablation.
Study: NCT01383928

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ixazomib
Description: Ixazomib capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ixazomib
Description: Ixazomib capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide capsules

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone Tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone Tablets
Study: NCT02535312

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methoxyamine
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methoxyamine
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed Disodium
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed Disodium
Description: Given IV
Study: NCT04039087

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sildenafil 40mg oral capsule
Description: 40 mg, sildenafil capsule taken by mouth thrice daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral capsule
Description: Placebo capsule taken by mouth thrice daily
Study: NCT02843893

Intervention type: DEVICE
Group type: OTHER
Intervention: Measure the minimum intensity of a painful stimulation
Description: With Neurolight device.
Study: NCT00626301

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LPV/r
Description: LPV/r 230/57.5 mg/m2 orally q12h or the adjusted dose based on therapeutic drug monitoring of LPV/r prior to enrollment as maintenance monotherapy
Study: NCT01045343

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated diagnositic system
Description: Heart failure will be managed using the integrated diagnostic system which consists of patient tools and a new Heart Failure Clinician's website which displays a new Heart Failure Risk score. This Heart Failure Clinician's website will be reviewed every 2 weeks in addition to scheduled in-office visits every three months.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine in office visits
Description: Heart failure will be managed with scheduled in-office visits every three months.
Study: NCT03887078

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Coach for Bariatric Health
Description: Noom Coach for Bariatric Health offers a sustainable, low-cost, coach-led intervention, and an innovative solution to issues with pre-bariatric surgery weight loss. The intervention will take place over 8 weeks pre and or post-surgery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Coach for Bariatric Health
Description: Noom Coach for Bariatric Health offers a sustainable, low-cost, coach-led intervention, and an innovative solution to issues with pre-bariatric surgery weight loss. The intervention will take place over 8 weeks pre and or post-surgery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Coach for Bariatric Health
Description: Noom Coach for Bariatric Health offers a sustainable, low-cost, coach-led intervention, and an innovative solution to issues with pre-bariatric surgery weight loss. The intervention will take place over 8 weeks pre and or post-surgery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Coach for Bariatric Health
Description: Noom Coach for Bariatric Health offers a sustainable, low-cost, coach-led intervention, and an innovative solution to issues with pre-bariatric surgery weight loss. The intervention will take place over 8 weeks pre and or post-surgery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Coach for Bariatric Health
Description: Noom Coach for Bariatric Health offers a sustainable, low-cost, coach-led intervention, and an innovative solution to issues with pre-bariatric surgery weight loss. The intervention will take place over 8 weeks pre and or post-surgery.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Coach for Bariatric Health
Description: Noom Coach for Bariatric Health offers a sustainable, low-cost, coach-led intervention, and an innovative solution to issues with pre-bariatric surgery weight loss. The intervention will take place over 8 weeks pre and or post-surgery.
Study: NCT04223739

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Landiolol
Description: Landiolol infusion with incremental doses (range from 2,5µg/kg/min to 80 µg/kg/min) with go of heart rate \< 90 bpm. Doses are modified every 10 minutes if necessary.~Once heart rate goal is obtained, switch to an oral dose of Bisoprolol.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amiodarone
Description: Amiodarone loading dose of 5-7 mg/kg in 1 hour followed by an infusion of 1 g/day until conversion to sinus rhythm. Once sinus rhythm is obtained, switch to an oral dose of 200mg/day
Study: NCT00116883

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GW685698X aqueous nasal spray
Study: NCT02232607

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacidipine, low dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacidipine, medium dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lacidipine, high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Study: NCT00795366

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: arginine vasopressin
Description: Titrated to cerebral perfusion pressure greater than 60 mm Hg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard catecholamine
Description: Titrated catecholamine of attending physicians preference to cerebral perfusion pressure greater than 60 mm Hg.
Study: NCT04221399

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001
Description: Tablets, Oral, Once daily, Single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001
Description: Tablets, Oral, Once daily, Multiple dose
Study: NCT02387229

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rivaroxaban
Description: 15 mg

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: standard of care
Study: NCT02469389

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Engaging in Community Roles and Experiences (ENCoRE)
Description: Engaging in Community Roles and Experiences (ENCoRE) includes evidence-based psychosocial treatment strategies to target the affective-motivational deficits, negative expectancies, and behavioral skills deficits that are central to the maintenance of negative symptoms. Behavioral strategies include motivational enhancement, psychoeducation, cognitive therapy, and social skills training.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health & Wellness (H&W)
Description: Health \& Wellness (H\&W) will focus on health and wellness issues and education on ways to better manage health-related concerns following a basic structure that includes: review of the previous session's material, new educational content, and discussion/application.~Topics will include: 1) Overview, 2) Physical Activity (3 sessions), 3) Nutrition/Healthy Eating (3 sessions), 4) Managing Fatigue/Sleep (3 sessions), 5) Relaxation (3 sessions), 6) Tobacco cessation (3 sessions), 7) Substance Use (3 sessions), 8) Medication/Side Effects (3 sessions), 9) Review (1 session), and Closing (1session).
Study: NCT01018303

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: AquADEK
Description: Two AquADEK softgel vitamins on a daily basis x 12 weeks
Study: NCT03254485

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IW-1973
Description: Oral Tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral Tablet
Description: Oral Tablet
Study: NCT03831373

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: Three physical exercise programs, two of resistance training with elastic bands and one of stretching exercises, all performed in a sitting position.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical exercise
Description: Three physical exercise programs, two of resistance training with elastic bands and one of stretching exercises, all performed in a sitting position.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: Three physical exercise programs, two of resistance training with elastic bands and one of stretching exercises, all performed in a sitting position.
Study: NCT04371198

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Tissue biopsy
Study: NCT01604629

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reduced doses of anti-TNF
Description: Standardized schedule of reduced doses of anti-TNF, reached either through the interval spacing of administration (adalimumab, etanercept or golimumab) or reducing doses of infliximab

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Stable doses of anti-TNF
Description: Stable doses of anti-TNF according clinical practice based on approved summary product characteristics (SPC) and SER consensus about biological therapies in Ankylosing Spondylitis and other Spondylarthropathies, except Psoriatic Arthritis
Study: NCT01455805

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Minuteman Fusion Implant
Description: The Minuteman™ interspinous interlaminar fusion device consists of a central threaded portion that has a two-part wing plate hinged near its proximal end, with spikes on the extended distal end of the wing plate, and a multi-spiked end cap plate that is located at the distal end of the device and is retained and tightened in place with a locking hex nut. Compression between the spiked wing plate and the spiked end cap plate serves to fix the spinous processes in place and to facilitate fusion, together with bone graft fusion material placed within the device. The threaded external body has been designed to provide ease of distraction and insertion via a minimally invasive surgical procedure.

Intervention type: PROCEDURE
Group type: OTHER
Intervention: surgical decompression
Description: Surgical decompression refers to the following operations Laminectomy, Foraminotomy, Discectomy or any other surgical procedure that the clinician feels is relevant for the decompression of lumbar spinal stenosis
Study: NCT02015182

Intervention type: OTHER
Intervention: Blood sample for bupivicaine pharmacokinetics
Description: Bupivacaine levels will be measured with an assay developed on the 4000 QTrap Tandem Mass Spectrometer (Applied Biosystems/ MDS Sciex).~Data will be collected and analyzed using the Agilent ChemStation software (Rev A.10.02). The analytical column is an Agilent Zorbax Eclipse XDB-C8 (4.6 x 150mm, 5µm).Quantification of bupivacaine is based on analyzing a six point calibration curve (0 to 4.0 mg/L). An internal standard (Prilocaine 221.2/86.1) is included with each calibrator, quality control or patient sample. Instrumentation and Chromatographic conditions: The HPLC system consists of a Specta-System P1000 Isocratic Pump and an AS3000 Autosampler (Thermo Electron Corporation, Waltham MA).
Study: NCT00050037

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CBT

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CBT
Study: NCT01878214

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted messaging
Description: 6 targeted mailed messages and 6 booster text messages

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard messaging
Description: 1 informational letter

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard messaging
Description: 1 informational letter
Study: NCT04962243

Intervention type: PROCEDURE
Intervention: Repair surgery for Achilles tendon rupture
Description: Repair surgery for Achilles tendon rupture
Study: NCT04646538

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Regenerative Endodontics Procedures (REPs)
Description: REPs was done for 10 mature maxillary necrotic teeth with periapical lesions. Instrumentation was done using Protaper Next system till size X3. Irrigation with 1.5 % NaOCl was done in the first visit. in the second visit, bleeding was induced in the canal by irritating the periapical area followed by the application of Biodentine as cervical plug then completion of the coronal restoration.
Study: NCT01928251

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Informed early monetary incentive
Description: Participants will be informed at 1 week after the baseline recruitment about the monetary incentive of quitting.~Apart from the different arrangement of monetary incentives for the three RCT arms, all participants of the Quit to Win Contest will receive self-help materials on smoking cessation, including a COSH-developed self-help smoking cessation booklet, a health education card, and the quitline (i.e. 1833183). The theory-based health education card (pocket size), which guided by the HAPA, will be developed and distributed to the participants as a reminder and a 'homework assignment' to be completed at home, for the purpose of enhancing their intention and practice of the suggested behaviour (quitting smoking).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Uninformed early monetary incentive
Description: Participants will be informed at 3 months after the baseline recruitment about the monetary incentive of quitting.~Apart from the different arrangement of monetary incentives for the three RCT arms, all participants of the Quit to Win Contest will receive self-help materials on smoking cessation, including a COSH-developed self-help smoking cessation booklet, a health education card, and the quitline (i.e. 1833183). The theory-based health education card (pocket size), which guided by the HAPA, will be developed and distributed to the participants as a reminder and a 'homework assignment' to be completed at home, for the purpose of enhancing their intention and practice of the suggested behaviour (quitting smoking).
Study: NCT04565847

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Salbutamol 5mg/mL
Description: Nebulized salbutamol given prior to Mannitol-Induced Cough Challenge

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sodium Chloride 0.9% Inhl 3Ml
Description: Nebulized 0.9% saline given prior to Mannitol-Induced Cough Challenge
Study: NCT04042493

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Connect for Health
Description: The program includes (1) electronic health record (EHR)-based clinical decision support tools to guide pediatric providers in child weight management; (2) clinician and medical staff training in obesity management best practices, (3) family educational materials focused on evidence-based behavioral targets; and (4) social- and community-informed text messages for parents to support behavior change.
Study: NCT03117322

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: agave inulin
Description: Duration: four weeks Dosage: powder 4 g/d

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: agave inulin
Description: Duration: four weeks Dosage: powder 4 g/d

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lactobacillus reuteri DSM 17938
Description: Duration: four weeks Dosage: 5 drops/d

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lactobacillus reuteri DSM 17938
Description: Duration: four weeks Dosage: 5 drops/d

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: maltodextrin
Description: Duration: four weeks Dosage: powder 4 g/d

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: maltodextrin
Description: Duration: four weeks Dosage: powder 4 g/d

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Oil mix (medium chain triglycerides and sunflower oil)
Description: Duration: four weeks Dosage: 5 drops/d

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oil mix (medium chain triglycerides and sunflower oil)
Description: Duration: four weeks Dosage: 5 drops/d
Study: NCT03141723

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: KMC & WHO protocol (0-1 hour)
Description: WHO thermoregulation care - warm delivery rooms, immediate drying after birth, early and exclusive breastfeeding, postponement of bathing and weighing, and appropriate bundling.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: KMC, WHO protocol & bag (0-1 hour)
Description: In addition infants will be placed in a plastic bag (clear polyethylene nonmedical low-cost \[3 cents per bag\] linear low-density bag measuring 10 × 8 × 24 in. and 1.2 mil thick) that will cover the infant's torso and lower extremities.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: KMC & WHO protocol (1-24 hours)
Description: WHO thermoregulation care - warm delivery rooms, immediate drying after birth, early and exclusive

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: KMC, WHO protocol & bag (1-24 hours)
Description: In addition infants will be placed in a plastic bag (clear polyethylene nonmedical low-cost \[3 cents per bag\]
Study: NCT00249002

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABI-007
Study: NCT03256851

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telephone-Delivered Exercise Therapy
Description: A combination of aerobic and resistance training has been shown to be most effective for reducing fatigue in persons with MS.~Aerobic training will consist of: 30 minutes of either cycling, treadmill walking or overground walking, 2x/week. Participants will be given a wrist-worn pedometer with heart-rate monitor to track their heart rate during training. Participants will be progressed to reach 60-70% of their maximal heart rate during aerobic training over the course of the study.~Strength training will consist of hip extension, hip flexion, hip abduction, knee extension and knee flexion movements with resistance bands performed 3x/week.~This home exercise program will be paired with a 1x/week telephone call with an investigator.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: In-Person Delivered Exercise Therapy
Description: A combination of aerobic and resistance training has been shown to be most effective for reducing fatigue in persons with MS.~Aerobic training will consist of: 30 minutes of either cycling, treadmill walking or overground walking, 2x/week. Participants will be given a wrist-worn pedometer with heart-rate monitor to track their heart rate during training. Participants will be progressed to reach 60-70% of their maximal heart rate during aerobic training over the course of the study.~Strength training will consist of hip extension, hip flexion, hip abduction, knee extension and knee flexion movements with resistance bands performed 3x/week.~This home exercise program will be paired with a 1x/week visit to the laboratory to work with a physical therapist or trained team member.