Study: NCT03258593

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antihistamine
Description: Antihistamine (e.g., diphenhydramine) or equivalent medications per institutional standard may be administered at the discretion of the investigator.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bladder Biopsy
Description: Bladder biopsy at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bladder Biopsy
Description: Bladder biopsy at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bladder Biopsy
Description: Bladder biopsy at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bladder Biopsy
Description: Bladder biopsy at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TURBT
Description: Transurethral resection of a bladder tumor (TURBT) at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TURBT
Description: Transurethral resection of a bladder tumor (TURBT) at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TURBT
Description: Transurethral resection of a bladder tumor (TURBT) at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TURBT
Description: Transurethral resection of a bladder tumor (TURBT) at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cystoscopy
Description: Urine cytology at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cystoscopy
Description: Urine cytology at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cystoscopy
Description: Urine cytology at screening and every 3 months before each cystoscopy per schema.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cystoscopy
Description: Urine cytology at screening and every 3 months before each cystoscopy per schema.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Urine cytology
Description: Urine cytology at baseline and every 3 months before each cystoscopy per schema.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Urine cytology
Description: Urine cytology at baseline and every 3 months before each cystoscopy per schema.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Urine cytology
Description: Urine cytology at baseline and every 3 months before each cystoscopy per schema.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Urine cytology
Description: Urine cytology at baseline and every 3 months before each cystoscopy per schema.

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Electrocardiogram
Description: Electrocardiogram (ECG) at screening, pre-durvalumb infusion and as clinically indicated during the trial.