Study: NCT02624973

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant tamoxifen + goserelin (premenopausal women)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant letrozole (postmenopausal women)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant endocrine therapy + palbociclib (if lack of response to endocrine therapy alone)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant docetaxel + cyclophosphamide

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant docetaxel + cyclophosphamide

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant docetaxel

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant docetaxel + trastuzumab + pertuzumab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant docetaxel + cyclophosphamide + trastuzumab + pertuzumab

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant olaparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant olaparib

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant cyclophosphamide (after 10 weeks of olaparib alone)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant cyclophosphamide (after 10 weeks of olaparib alone)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Breast conserving surgery or mastectomy + SNB/axillary dissection
Description: After response to neoadjuvant treatment

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Postoperative radiotherapy breast/chest wall + regional lymph nodes

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Postoperative radiotherapy breast/chest wall + regional lymph nodes

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Postoperative radiotherapy breast/chest wall + regional lymph nodes

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Postoperative radiotherapy breast/chest wall + regional lymph nodes

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Postoperative radiotherapy breast/chest wall + regional lymph nodes