Study: NCT04790708

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Lutetium-177 (177Lu)-DOTATOC
Description: 5 cycles of 3,7 e 5,55 gigabequerel (GBq) of 177Lu-DOTATOC every 8-10 weeks. Cumulative activity: 18,5 e 27,75 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Lutetium-177 (177Lu)-DOTATOC
Description: 5 cycles of 3,7 e 5,55 gigabequerel (GBq) of 177Lu-DOTATOC every 8-10 weeks. Cumulative activity: 18,5 e 27,75 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Lutetium-177 (177Lu)-DOTATOC
Description: 5 cycles of 3,7 e 5,55 gigabequerel (GBq) of 177Lu-DOTATOC every 8-10 weeks. Cumulative activity: 18,5 e 27,75 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Lutetium-177 (177Lu)-DOTATOC
Description: 5 cycles of 3,7 e 5,55 gigabequerel (GBq) of 177Lu-DOTATOC every 8-10 weeks. Cumulative activity: 18,5 e 27,75 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Lutetium-177 (177Lu)-DOTATOC
Description: 5 cycles of 3,7 e 5,55 gigabequerel (GBq) of 177Lu-DOTATOC every 8-10 weeks. Cumulative activity: 18,5 e 27,75 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Lutetium-177 (177Lu)-DOTATOC
Description: 5 cycles of 3,7 e 5,55 gigabequerel (GBq) of 177Lu-DOTATOC every 8-10 weeks. Cumulative activity: 18,5 e 27,75 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Yttrium-90 (90Y)-DOTATOC
Description: 5 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks. Cumulative activity: 9,25 e 13,875 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Yttrium-90 (90Y)-DOTATOC
Description: 5 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks. Cumulative activity: 9,25 e 13,875 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Yttrium-90 (90Y)-DOTATOC
Description: 5 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks. Cumulative activity: 9,25 e 13,875 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Yttrium-90 (90Y)-DOTATOC
Description: 5 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks. Cumulative activity: 9,25 e 13,875 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Yttrium-90 (90Y)-DOTATOC
Description: 5 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks. Cumulative activity: 9,25 e 13,875 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Yttrium-90 (90Y)-DOTATOC
Description: 5 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks. Cumulative activity: 9,25 e 13,875 GBq

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTATOC + 90Y-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC alternated with 2 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks.~Cumulative activity: 18,5 e 27,75 GBq of 177Lu-DOTATOC and 9,25 e 13,875 GBq of 90Y-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTATOC + 90Y-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC alternated with 2 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks.~Cumulative activity: 18,5 e 27,75 GBq of 177Lu-DOTATOC and 9,25 e 13,875 GBq of 90Y-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTATOC + 90Y-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC alternated with 2 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks.~Cumulative activity: 18,5 e 27,75 GBq of 177Lu-DOTATOC and 9,25 e 13,875 GBq of 90Y-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTATOC + 90Y-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC alternated with 2 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks.~Cumulative activity: 18,5 e 27,75 GBq of 177Lu-DOTATOC and 9,25 e 13,875 GBq of 90Y-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTATOC + 90Y-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC alternated with 2 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks.~Cumulative activity: 18,5 e 27,75 GBq of 177Lu-DOTATOC and 9,25 e 13,875 GBq of 90Y-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTATOC + 90Y-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC alternated with 2 cycles of 1,85 e 2,775 GBq of 90Y-DOTATOC every 8-10 weeks.~Cumulative activity: 18,5 e 27,75 GBq of 177Lu-DOTATOC and 9,25 e 13,875 GBq of 90Y-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-treatment 177Lu-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC every 8-10weeks. Cumulative activity: 11,1 e 16,65 GBq of 177Lu-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-treatment 177Lu-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC every 8-10weeks. Cumulative activity: 11,1 e 16,65 GBq of 177Lu-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-treatment 177Lu-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC every 8-10weeks. Cumulative activity: 11,1 e 16,65 GBq of 177Lu-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-treatment 177Lu-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC every 8-10weeks. Cumulative activity: 11,1 e 16,65 GBq of 177Lu-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-treatment 177Lu-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC every 8-10weeks. Cumulative activity: 11,1 e 16,65 GBq of 177Lu-DOTATOC

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-treatment 177Lu-DOTATOC
Description: 3 cycles of 3,7 e 5,55 GBq of 177Lu-DOTATOC every 8-10weeks. Cumulative activity: 11,1 e 16,65 GBq of 177Lu-DOTATOC