Study: NCT03287310

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3511294
Description: GSK3511294 will be available as a clear or opalescent, colorless or yellow to brown solution for injection at unit dose strength of 150 milligrams per milliliter (mg/mL). GSK3511294 will be diluted in 0.9% weight by volume (w/v) sodium chloride to achieve the desired concentration for administration. GSK3511294 will be administered by SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3511294
Description: GSK3511294 will be available as a clear or opalescent, colorless or yellow to brown solution for injection at unit dose strength of 150 milligrams per milliliter (mg/mL). GSK3511294 will be diluted in 0.9% weight by volume (w/v) sodium chloride to achieve the desired concentration for administration. GSK3511294 will be administered by SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3511294
Description: GSK3511294 will be available as a clear or opalescent, colorless or yellow to brown solution for injection at unit dose strength of 150 milligrams per milliliter (mg/mL). GSK3511294 will be diluted in 0.9% weight by volume (w/v) sodium chloride to achieve the desired concentration for administration. GSK3511294 will be administered by SC injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK3511294
Description: GSK3511294 will be available as a clear or opalescent, colorless or yellow to brown solution for injection at unit dose strength of 150 milligrams per milliliter (mg/mL). GSK3511294 will be diluted in 0.9% weight by volume (w/v) sodium chloride to achieve the desired concentration for administration. GSK3511294 will be administered by SC injection.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Salbutamol/albuterol
Description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.