TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT00790192

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lurasidone
Description: Lurasidone 80 mg tablets

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lurasidone
Description: Lurasidone 4 40 mg tablets

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Quetiapine XR
Description: Quetiapine XR 600mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo to Lurasidone or Quetiapine
Study: NCT03550274

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: App-based exercise rehabilitation
Description: App-based exercise rehabilitation available on any mobile device and/or tablet using Android or iOS operating systems. The app Injurymap© is hosting the exercise program. The app requires user-registrations and a monthly paid subscription fee to access the exercise program. The participants in this study will not be charged for using the app.~The exercise program consists of three phases with increasing difficulty. Each phase consists of several categories of exercise types. The categories are 1) mobility, 2) stability/balance, 3) strength and 4) stretching. Within each phase, there can be more than one exercise for each category. This makes it possible to adjust the difficulty of the exercises depending on user-feedback.
Study: NCT03769259

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Cognitive Behavioral Therapy (BCBT)
Description: Participants in BCBT receive 12 outpatient individual psychotherapy sessions scheduled on a weekly or biweekly basis, with the first session lasting 90 minutes and subsequent sessions lasting 60 minutes. BCBT was is delivered in three sequential phases. In phase I (5 sessions), the therapist identifies patient-specific factors that contribute to and maintain suicidal behaviors, provides a cognitive-behavioral conceptualization, collaboratively develops a crisis response plan, and teaches basic emotion regulation skills. In phase II (5 sessions), the therapist applies cognitive strategies to reduce beliefs and assumptions that serve as vulnerabilities to suicidal behavior. In phase III (2 sessions), a relapse prevention task is conducted.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Present-Centered Therapy (PCT)
Description: Participants in PCT will receive will include 12 outpatient individual psychotherapy sessions scheduled on a weekly or biweekly basis, with the first session lasting 90 minutes and subsequent sessions lasting 60 minutes. PCT consists of (1) psychoeducation about the typical symptoms and features associated with suicidal thoughts and behaviors among military personnel; (2) normalization of symptoms; (3) experience of receipt of support and feedback from a licensed professional; and (4) positive interpersonal interactions.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treatment as Usual (TAU)
Description: All participants will receive the following interventions or procedures, regardless of treatment assignment:~* Suicide risk assessment using the Columbia Suicide Severity Rating Scale~* VA's safety planning intervention, which include Military Crisis Line contact information and lethal means access reduction~* Caring contacts and outreach~* Psychotropic medication, group therapy, substance abuse counseling, and other mental health interventions provided routinely as a part of treatment as usual

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual (TAU)
Description: All participants will receive the following interventions or procedures, regardless of treatment assignment:~* Suicide risk assessment using the Columbia Suicide Severity Rating Scale~* VA's safety planning intervention, which include Military Crisis Line contact information and lethal means access reduction~* Caring contacts and outreach~* Psychotropic medication, group therapy, substance abuse counseling, and other mental health interventions provided routinely as a part of treatment as usual
Study: NCT04590560

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: screening for breast cancer with tomosynthesis and synthetic 2D mammography performed at different interval compared to actual clinical practice
Description: women will be screened for breast cancer using tomosynthesis and synthetic 2D mammography with an interval defined according to their randomization arm for a follow-up period of 6 years;

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: screening for breast cancer with tomosynthesis and synthetic 2D mammography performed at different interval compared to actual clinical practice
Description: women will be screened for breast cancer using tomosynthesis and synthetic 2D mammography with an interval defined according to their randomization arm for a follow-up period of 6 years;
Study: NCT01101789

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: triclosan coated suture for surgical wound closure
Description: triclosan coated suture for surgical wound closure

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: regular sutures for surgical wound closure
Study: NCT00056693

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sunitinib
Description: Sunitinib 50 mg by oral capsule daily for 4 weeks in every 6 week cycle until progression or unacceptable toxicity
Study: NCT02766712

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pace During 1st Half of Lesion

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pace During 2nd Half of Lesion
Study: NCT02847559

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Given IV

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electric Field Therapy
Description: Undergo electric field therapy using Optune device

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NovoTTF-200A Device
Description: Undergo electric field therapy using Optune device

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study: NCT04372420

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RhBMP-2 absorbable sponge in grade II furcation
Description: The collagen sponge is impregnated with rhBMP-2 at a concentration of 0.5 μg/ml/1cm3 and were stored at 4°C. This rhBMP-2 impregnated collagen sponge was then dispensed at grade II furcation site

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: PLATELET RICH FIBRIN in grade II furcation
Description: For preparation of PRF, patient's venous blood is collected into 10ml glass tube or glass-coated plastic tube and centrifuged at 2700 rpm for 12min which leads to two different layers in the test tube, the upper platelet rich fibrin and the lower RBC portion. The formed PRF clot could then be removed from the glass tube and used in grade II furcation
Study: NCT01839058

Intervention type: OTHER
Intervention: Esophageal Manometry
Description: Both cohorts will undergo standard high resolution esophageal manometry testing. This entails a catheter passed through the nose into the esophagus and measures pressure changes with a series of wet swallows. As part of the study, we will also be instilling both weak acid and saline into the esophagus.

Intervention type: OTHER
Intervention: Esophageal Manometry
Description: Both cohorts will undergo standard high resolution esophageal manometry testing. This entails a catheter passed through the nose into the esophagus and measures pressure changes with a series of wet swallows. As part of the study, we will also be instilling both weak acid and saline into the esophagus.
Study: NCT03029468

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive behavioral therapy
Description: CBT teaches users how to recognize negative thoughts and emotions, use cognitive skills and problem-solving, and apply coping behaviors such as distraction, activity scheduling, and relaxation.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: eEducation
Description: Pain and sickle cell disease education delivered through a mobile electronic device
Study: NCT02538601

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT-A
Description: CBT-A was an 8-session (1.5 hours/session) group treatment for quitting smoking comprised of an optimized protocol that incorporated all elements of the CBT-S treatment plus skills for reducing PTSD/anxiety symptoms and improving tolerance to withdrawal. The CBT-A intervention included skills based on a transdiagnostic approach: (1) repeated interoceptive exposures to feared bodily sensations (e.g., dizziness, racing heart); (2) corrective information about anxiety and cognitive restructuring of catastrophic misinterpretations of somatic sensations (e.g., I will lose control.); and (3) use of graduated in-vivo exposure to feared and avoided situational experiences related to anxiety, WTC-related PTSD triggers, and smoking (e.g., going to lower Manhattan; driving without smoking).

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CBT-S
Description: CBT-S was an adapted group-based CBT smoking cessation treatment delivered in 8 sessions (1.5 hours/session) based on the most recent clinical practice guidelines from the United States Department of Health and Human Services (USDHHS), Treating Tobacco Use and Dependence. Standard cessation elements included psychoeducation on reasons for smoking and barriers to quitting, enlisting social support, monitoring and tapering cigarette use, and counseling regarding high-risk smoking situations and unhelpful ways of thinking about smoking and abstinence. The treatment was similar to protocols used in other smoking cessation research.
Study: NCT04414163

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMC-001
Description: Single dose level for enrollment subject (IMC-001 20mg/kg every 2 weeks)
Study: NCT00980356

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vildagliptin
Description: Patients receive once daily 50 mg Vildagliptin
Study: NCT02361333

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Teaching Intervention
Description: Patients will be taught how to install and use a remote monitor
Study: NCT00106327

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 6 months of supervised treadmill exercise or strength training, three times per week, followed by a 6 month home-based program.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 6 months of supervised treadmill exercise or strength training, three times per week, followed by a 6 month home-based program.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diet
Description: 11 nutrition education sessions
Study: NCT04469712

Intervention type: PROCEDURE
Intervention: SASI Bipartition
Description: SASI Bipartition is performed with a sleeve gastrectomy over a 32 French gastric bougie and a 300 cm common limb. Side-to-side gastroileostomy with a diameter of approximately 2.5 cm at the anterior part of antrum, 6 cm proximal to pylorus.

Intervention type: PROCEDURE
Intervention: Gastric bypass
Description: A small gastric pouch (15 mL) is created, and the jejunum brought up as an antecolic and antegastric fashion. Routine limb lengths were 150 cm for the alimentary limb and 60 cm for the bilio-pancreatic limb. Both mesenteric defects are closed with the Endohernia® stapler.
Study: NCT04389008

Intervention type: OTHER
Intervention: no interventions
Description: no interventions

Intervention type: OTHER
Intervention: no interventions
Description: no interventions
Study: NCT00347776

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: azithromycin
Description: oral antibiotic

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: azithromycin
Description: oral antibiotic

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: topical tetracycline
Study: NCT03735680

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONM-100
Description: A polymer micelle covalently conjugated to indocyanine green.
Study: NCT01159652

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: zaleplon
Description: 10 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: zolpidem extended release
Description: 12.5 mg
Study: NCT00819936

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: forward walking
Description: comparison forward walking vs backward walking in the physiotherapy after after abdominal surgery
Study: NCT02896153

Intervention type: OTHER
Intervention: Questionnaire
Study: NCT02480283

Intervention type: PROCEDURE
Intervention: Bronchoscopy
Description: Passage of a thin flexible tube through the mouth, into the windpipe and then into the bronchial tubes so that the study doctor can look into the lungs to perform Bronchoalveolar lavage (BAL), cytologic brushing, and protected specimen brushing.
Study: NCT00819936

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: backward walking
Description: physiotherapy with use a backward walking type of physiotherapy
Study: NCT01159652

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: bedtime placebo
Description: placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: middle of the night placebo
Description: placebo
Study: NCT01366599

Intervention type: DRUG
Intervention: HEC or MEC
Description: Any HEC or MEC, including aprepitant
Study: NCT03273816

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sessions of sophrology
Description: 10 sessions of sophrology in preparation for the intervention 5 weeks before this one.
Study: NCT03500029

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Transcranial magnetic stimulation (TMS)
Description: TMS treatment group is treated with TMS for 20-40 minutes a time, 5 times a week. The stimulation parameters were 20 Hz and 80% MT. Each stimulation continues for 2 seconds, and the interval time of stimulation is 58 seconds.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: antidepressants
Description: Medication group is treated with anti-depression for 6 weeks. The drugs and their doses belong to the first-line treatment for depression in the current guideline .
Study: NCT01250418

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine group
Description: ketamine bolus of 0.25mg/kg followed by an infusion set at 1.5 mcg /kg/min.
Study: NCT04566965

Intervention type: DIAGNOSTIC_TEST
Intervention: SARS-CoV-2
Description: 1. Testing weekly samples from nasal swabs to promptly diagnose acute COVID-19 infection.~2. Testing monthly serum samples to document post-viral infection.
Study: NCT02026986

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sleep deprivation
Description: sleep deprivation for one night
Study: NCT05330832

Intervention type: DIAGNOSTIC_TEST
Intervention: Thrombodynamics test
Description: Thrombodynamics test is a global hemostasis test that allows to register the dynamics of fibrin clot formation in time and space. It requires whole blood samples from included patients.
Study: NCT01645254

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Argemone mexicana
Description: 30g, the powder decoction 2 times a day for 14 days
Study: NCT02373488

Intervention type: OTHER
Group type: OTHER
Intervention: lifestyle advice
Description: lifestyle advices such as increasing fluid and fibre intake, improving physical activity level, and taking the ideal posture for defecation (squatting position) with a two-pages document.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: lifestyle advice
Description: lifestyle advices such as increasing fluid and fibre intake, improving physical activity level, and taking the ideal posture for defecation (squatting position) with a two-pages document.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: lifestyle advice
Description: lifestyle advices such as increasing fluid and fibre intake, improving physical activity level, and taking the ideal posture for defecation (squatting position) with a two-pages document.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: connective tissue manipulation
Description: CTM wil be applied five days per week, a total of 20 sessions for 4 weeks. Each session lasted around 15-20 minutes. While patients are in a sitting position, starting from the lumbosacral region, lower thoracic, scapular, inter-scapular and cervical regions will be included in the treatment, respectively.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: abdominal massage
Description: Abdominal massage will be applied five days a week for four weeks. Each session will last around 15-20 minutes.
Study: NCT03594773

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy
Description: Participants will receive 8 one-on-one sessions over 8 to 12 weeks.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interpersonal Psychotherapy
Description: Participants will receive 8 one-on-one sessions over 8 to 12 weeks.
Study: NCT03255317

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Reinforcers
Description: Memes/Gifs: Immediately after completing their daily ecological momentary assessment using the app, each participant is randomized to receive an inspirational or funny meme or gif that is displayed within the app. Life Insights: Immediately after completing both daily active tasks using the app, each participant is randomized to unlock a life insight. Life insights track data provided by the participant, are stored in a virtual library within the app, and are regularly updated with recent data points.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Notifications
Description: Reminder Push Notifications: All participants receive a push notification reminder from the app at 6pm (the time at which data collection opens) to complete their daily data collection activities. Each day, each participant will be randomized to receive either a generic reminder or a reminder that contains more detailed information (e.g., about upcoming incentives). Inspirational Push Notifications: Each day, each participant will be randomized to receive a push notification at 4pm that contains inspirational song lyrics or celebrity quotes.
Study: NCT03191630

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fitbit (Control)
Description: Study procedures include group sessions at the OSU Transplant Clinic with 10-12 participants for 6 months and a 6-month maintenance phase without contact from study personnel until month 12. Session 1 for the control group will be identical to the Intervention with the only exception being that participants in the control group will not be asked to increase their step goal. Throughout their participation, subjects will be asked questions only about their use of the Fitbit activity tracker. The research team will not be in contact with them for 6 months, after which time there will be a final group session.
Study: NCT02335138

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: at-home test kit
Description: Male couples in the control group will receive test kits, but will not receive any testing intervention. Once individual results are reported,participants will be contacted via phone by study staff with options for referrals to services for the reactive partner(s). Participants will complete follow-up surveys at 3 and 6 months post-testing.
Study: NCT03191630

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SystemCHANGE and Fitbit (Intervention)
Description: Study procedures include group sessions with 10-12 participants for 6 months and a 6-month maintenance phase without contact from study personnel until month 12. Study personnel will demonstrate proper Fitbit activity tracker use, and teach participants to sync to their smartphone and retrieve data from their Fitbit. Subjects will be called to encourage them to increase their step goal 5% each month. Fitbit activity tracker reports will be reviewed and participants will be asked to identify what people or things influence their physical activity. Subjects will be asked what they are learning about physical activity, their contentment level with current physical activity, and if they want to make changes. Participants will continue for months, after which time there will be a final group session.
Study: NCT04359199

Intervention type: RADIATION
Intervention: Radiation Therapy
Description: Routine radiation dosing (approximately 70 Gy in 35 fractions over 6.5 weeks) to the head and neck for the treatment of head and neck cancer
Study: NCT01086592

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No intervention
Description: Daily life activities

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strong progressive strengthening exercises of lower limbs
Description: Lower limb weight

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrotherapy
Description: Neuromuscular Electrical Nerve Stimulation

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrotherapy+weights
Description: Superimposed Neuromuscular Electric Nerve Stimulation
Study: NCT03434756

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Propioceptive training of the abdominal wall muscles
Description: At the beginning, patients will be in a supine position, the lower edge of the StabilizerTM will be placed between the posterior superior iliac spines, aligned with the sacral base. Abdominal manoeuvre will be developed by the patients until they reach 40 mmHg and hold steadily for 10 seconds. Prior the examination, each subject practiced the abdominal manoeuvre three times with an ultrasound image feedback.
Study: NCT00816166

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pharos Vitesse Neurovascular Stent System (Stent implantation) + Medical therapy (Aspirin and Clopidogrel)
Description: Implantation of one or more balloon-expandable Pharos Vitesse stents to treat neurovascular ischemic lesions + Medical therapy \[Treatment with aspirin (81-325 mg daily for the duration of the study) and Clopidogrel (75 mg daily for first 3 months)\]

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin and Clopidogrel (Medical therapy)
Description: Medical therapy alone \[Treatment with aspirin (81-325 mg daily for the duration of the study) and Clopidogrel (75 mg daily for first 3 months)\]
Study: NCT02823223

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Zephyr endobronchial valve placement
Description: Patients will have ELVR (Endoscopic Lung Volume Reduction) with Zephyr valve inserted into the target lobe of the lung with the aim of complete lobar exclusion.