TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04263337

Intervention type: DRUG
Group type: OTHER
Intervention: [18F] Flortaucipir
Description: Per study protocol static PET images will be acquired after IV infusion of F-T807 to generate standard uptake values (SUVs). PET imaging is necessary in order to address the primary and secondary outcome measures as a component of neurological health (i.e., presence of proteinopathies empirically associated with neurodegenerative disease, cognitive decline, and neurological signs/symptoms). All groups will participate in this portion of the protocol.

Intervention type: DRUG
Group type: OTHER
Intervention: [18F] Flortaucipir
Description: Per study protocol static PET images will be acquired after IV infusion of F-T807 to generate standard uptake values (SUVs). PET imaging is necessary in order to address the primary and secondary outcome measures as a component of neurological health (i.e., presence of proteinopathies empirically associated with neurodegenerative disease, cognitive decline, and neurological signs/symptoms). All groups will participate in this portion of the protocol.

Intervention type: DRUG
Group type: OTHER
Intervention: [18F] Flortaucipir
Description: Per study protocol static PET images will be acquired after IV infusion of F-T807 to generate standard uptake values (SUVs). PET imaging is necessary in order to address the primary and secondary outcome measures as a component of neurological health (i.e., presence of proteinopathies empirically associated with neurodegenerative disease, cognitive decline, and neurological signs/symptoms). All groups will participate in this portion of the protocol.

Intervention type: DRUG
Group type: OTHER
Intervention: [18F] Flortaucipir
Description: Per study protocol static PET images will be acquired after IV infusion of F-T807 to generate standard uptake values (SUVs). PET imaging is necessary in order to address the primary and secondary outcome measures as a component of neurological health (i.e., presence of proteinopathies empirically associated with neurodegenerative disease, cognitive decline, and neurological signs/symptoms). All groups will participate in this portion of the protocol.
Study: NCT00457301

Intervention type: BEHAVIORAL
Intervention: HUI score card
Description: Patients completed the HUI2 and HUI3 before the encounter with the clinician, the result was graphically represented in the HUI score card. Clinicians used the HUI score card as an extra tool to help them in the management of the patients
Study: NCT04530526

Intervention type: PROCEDURE
Group type: OTHER
Intervention: Regenerative Peripheral Nerve Interface
Description: The regenerative peripheral nerve interface (RPNI) has emerged as a novel strategy to treat neuromas in peripheral nerves. The RPNI consists of the residual peripheral nerve end implanted in a skeletal muscle graft, following surgical resection of the injured terminal nerve portion (neuroma). The free muscle graft is separated from its native nerve innervation, leaving open neuromuscular junctions for ingrowth and attachment of nerve fibers from the implanted nerve.
Study: NCT01790893

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: aflibercept

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: aflibercept
Study: NCT04822324

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spencer Muscle energy technique with conventional Physiotherapy
Description: shoulder extension with elbow flexion. shoulder flexion with elbow extension. circumduction with compression circumduction with distraction shoulder abduction and internal rotation with elbow flexion. shoulder adduction and external rotation with elbow flexion stretching tissue and pumping fluids with the arm extended: therapist interlocks his fingertips over the deltoid muscle, patient's hand was placed over the therapist shoulder, and the therapist slowly moved the arm away from the shoulder and released.~During all the movements patient is asked to use their muscle energy against the slight resistance offered by the therapist for 6-8 sec.~conventional therapy Joint mobilization~Exercise therapy:~Self stretching and strengthening exercises

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Strain counter strain along with conventional Physiotherapy and Spencer Muscle energy technique
Description: Palpate surrounding and opposing tissues to locate tender point for both shoulder abduction and external rotation.~Use one or two finger pads to monitor fasciculation and TP. Fine-tune position with rotation. Hold the POC (position of comfort) until fasciculation decreases significantly or ceases.~Average positions hold time while pressure is 90 s to 3 min. Transient periods of brief tingling, numbness, and temperature changes might occur. Release tissue or joint slowly and reassess.
Study: NCT00364845

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Darbepoetin alfa
Description: Starting dose was calculated at 0.75 micrograms per kilogram (μg/kg) body weight at randomization, rounded to nearest prefilled syringe dose unit. Dose was titrated incrementally. Monthly dose was initially double the every 2 week dose at time of conversion.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Prefilled syringe placebo, to match active arm
Study: NCT00034541

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: cetuximab
Description: 400 mg/m2 i.v. over 120 minutes

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: paclitaxel
Description: 225 mg/m2, infusion

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: carboplatin
Description: 30-minute AUC = 6, infusion.
Study: NCT04734938

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Huel Powder
Description: Huel is made of an ultra-fine blend of sustainable ingredients. Oats, rice, peas, coconut, flaxseed, and our unique mix of vitamins and nutrients to provide you a meal with all the carbohydrates, protein, essential fats, fibre, and all the 26 essential vitamins and minerals your body needs to thrive. Volunteers will consume only Huel as their food source for the final four weeks of the study.
Study: NCT03697473

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Nordic hamstring exercise
Description: The exercise protocol consisted of the following sets and repetitions Week 1 - 2 sessions with 2 sets of 6 repetitions. Week 2 - 2 sessions with 3 sets of 6 repetitions Week 3 - 2 sessions with 4 sets of 8 repetitions. Week 4 - 2 sessions with 4 sets of 10 repetitions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hip extension exercise
Description: The exercise protocol consisted of the following sets and repetitions Week 1 - 2 sessions with 2 sets of 6 repetitions. Week 2 - 2 sessions with 3 sets of 6 repetitions Week 3 - 2 sessions with 4 sets of 8 repetitions. Week 4 - 2 sessions with 4 sets of 10 repetitions.
Study: NCT03999177

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kinect-TOLF Training System
Description: This system will teach patients to perform the lymphatic exercises correctly. Like playing the video games, patients follow the avatar model in the video to perform the lymphatic exercises. The Kinect system can automatically detect whether a user is performing the set of lymphatic exercises correctly in real time and provide instantaneous feedback to the user, thus enhancing patients' self-efficacy to perform the lymphatic exercises correctly. Patients will be asked to conduct two types of usability testing: heuristic evaluation and end-user testing.
Study: NCT00113503

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Azathioprine weight-based dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azathioprine individualised dose
Study: NCT03947801

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Greek Yogurt
Description: Female competitive soccer players (11-16y) will consume 0% plain Greek yogurt immediately following the training session, 1 h prior to bedtime, as well as one serving between breakfast and lunch on the subsequent day.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Isoenergetic carbohydrate
Description: Female competitive soccer players (11-16y) will consume an isoenergetic carbohydrate supplement immediately following the training session, 1 h prior to bedtime, as well as one serving between breakfast and lunch on the subsequent day.
Study: NCT03108677

Intervention type: OTHER
Intervention: Blood samples
Description: 15 ml peripheral blood

Intervention type: OTHER
Intervention: Blood samples
Description: 15 ml peripheral blood
Study: NCT04345991

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transfusion of COVID-19 convalescent plasma
Description: Two convalescent plasma units of 200 to 220 ml each will be transfused i.v. as early as possible and no later than 10 days after onset of clinical symptoms. In the absence of acute unforeseen adverse events in the first 3 patients, an additional 2 plasma units of 200/220 ml each will be transfused 24 hours after first 2 units: a total of 4 units / patient
Study: NCT04629807

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anterior Lumbar Interbody Fusion (ALIF)
Description: Intra-Operative Anterior Lumbar Interbody Fusion (ALIF)

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anterior Lumbar Interbody Fusion (ALIF)
Description: Intra-Operative Anterior Lumbar Interbody Fusion (ALIF)
Study: NCT01268969

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: KARYDAKIS GROUP
Description: The technique consisted of a vertical eccentric elliptical incision carried down to the post sacral fascia, complete removal of unhealthy tissue with the normal tissue around the cyst and sinus tracts, mobilization of the medial wound edge by undercutting the adipose tissue at a depth of 1 cm, the advancement of the flap across the midline to the post sacral fascia and suturing of its edge to the lateral one

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Lamberg flap technique
Description: The area to be excised was mapped on the skin in a rhomboid form . The skin incision was deepened to the presacral fascia centrally and to the gluteal fascia laterally. After removing the specimen, the Limberg fasciocutaneous flap was prepared by extending the incision down to and through the right gluteus maximus fascia
Study: NCT00207103

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivanib
Description: Tablets, Oral, 180 mg, once daily, until disease progression
Study: NCT00255112

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: family based cognitive behavior therapy
Description: newly developed family based cognitive behavior therapy for children with separation anxiety disorder over 5 years old
Study: NCT03925857

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allocetra-OTS
Description: Allocetra-OTS contains allogeneic donor mononuclear enriched cells in the form of a liquid suspension with at least 40% early apoptotic cells. The suspension is prepared with Ringer's lactate solution.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allocetra-OTS
Description: Allocetra-OTS contains allogeneic donor mononuclear enriched cells in the form of a liquid suspension with at least 40% early apoptotic cells. The suspension is prepared with Ringer's lactate solution.
Study: NCT01262911

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SRT2379
Description: SRT2379 will be supplied as hard gelatin capsules, with each containing 250mg.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo will be supplied as hard gelatin capsules, with each containing an appropriate amount of placebo.
Study: NCT02012283

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food consumption
Description: Cooked vegetables with spices or without spices

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Food consumption
Description: Cooked vegetables with spices or without spices
Study: NCT05108285

Intervention type: DIAGNOSTIC_TEST
Intervention: Optical Coherence Tomography Angiography (OCTA) and indocyanine green angiography (ICGA)
Description: OCTA and ICGA is able to detect the dark halo as a area of reduced perfusion around MVN
Study: NCT00207103

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivanib
Description: Tablets, Oral, 320 mg, once daily, until disease progression

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivanib
Description: Tablets, Oral, 600 mg, once daily, until disease progression

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivanib
Description: Tablets, Oral, 800 mg, once daily, until disease progression

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivanib
Description: Tablets, Oral, 800 mg, once daily (5 days on, 2 days off), until disease progression
Study: NCT02369016

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Copanlisib (BAY 80-6946)
Description: 60 mg of experimental drug in solution administered intravenously on Days 1, 8 and 15 of each 28-day treatment cycle
Study: NCT01702961

Intervention type: DRUG
Group type: OTHER
Intervention: Melphalan
Description: Given on Day -1~Melphalan is administered according to the current SOP.

Intervention type: DRUG
Group type: OTHER
Intervention: Ara-C
Description: 200 mg/m2 IB BID given on Days -5, -4, -3, -2

Intervention type: DRUG
Group type: OTHER
Intervention: VP-16
Description: 200 mg/m2 IV BID given on Days -5, -4, -3, -2

Intervention type: DRUG
Group type: OTHER
Intervention: BCNU
Description: BCNU 300 mg/m2 IV given on Day -6

Intervention type: DRUG
Group type: OTHER
Intervention: Rituxan
Description: 375 mg/m2 IB given on Days -6, +14, +21, +28

Intervention type: DRUG
Group type: OTHER
Intervention: Stem Cells
Description: Stem cells given on Day 0
Study: NCT04431180

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: blood donation SMS
Description: The literature shows that the information extraction and processing in emergency is different from the normal situation. To find the most effective emergency recruitment method during an outbreak, we intervened with a well-balanced group of donors by presenting different emergency recruitment text messages.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: blood donation SMS
Description: The literature shows that the information extraction and processing in emergency is different from the normal situation. To find the most effective emergency recruitment method during an outbreak, we intervened with a well-balanced group of donors by presenting different emergency recruitment text messages.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: blood donation SMS
Description: The literature shows that the information extraction and processing in emergency is different from the normal situation. To find the most effective emergency recruitment method during an outbreak, we intervened with a well-balanced group of donors by presenting different emergency recruitment text messages.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: blood donation SMS
Description: The literature shows that the information extraction and processing in emergency is different from the normal situation. To find the most effective emergency recruitment method during an outbreak, we intervened with a well-balanced group of donors by presenting different emergency recruitment text messages.
Study: NCT03277664

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: intervention group
Description: All the device-monitored adherence data from the previous week were downloaded from the background database and calculated by a qualified asthma nurse. Through free IMS (WeChat; Tencent, Shenzhen, CHN) available on mobile, the nurse offered feedback to the caregivers weekly according to the adherence rate and reminded them to keep taking the ICS. Caregivers were asked monthly Has our child inhaled the medicine according to the doctor's instructions? and How about the frequency? by telephone.
Study: NCT00207103

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brivanab
Description: Tablets, Oral, 1000 mg, once daily, until disease progression
Study: NCT02496728

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Health Application
Description: An application on a smart phone that is designed to help individuals self-monitor health behaviors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mobile Health Application
Description: An application on a smart phone that is designed to help individuals self-monitor health behaviors.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Environmental Cues
Description: Text messages, informational posts and reminders supporting healthy behaviors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Environmental Cues
Description: Text messages, informational posts and reminders supporting healthy behaviors.
Study: NCT01593657

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindful Movement and Breathing program
Description: Participate Mindful Movement and Breathing program with an experienced yoga instructor. All movements can be done while in a bed (e.g. turning head, shrugging shoulders, bending knees, etc). Each session lasts approximately 15 minutes.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire administration
Description: Collected at baseline (before surgery), before and after each YST session, and at follow-up (two days after surgery).

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: The Observer Mobility Scale
Description: Conducted by nurse and study coordinator prior to surgery and two days after surgery to assess mobility. Will ask patient to turn, sit, stand and walk as they are able.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Volumetric Incentive Spirometry
Description: Conducted twice before and after each Mindful Movement and Breathing program to measure lung function. Mean of the two readings used.
Study: NCT02496728

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Support
Description: Participants may interact with each other through a private Facebook group.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Social Support
Description: Participants may interact with each other through a private Facebook group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational Materials
Description: Educational materials regarding healthy behaviors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational Materials
Description: Educational materials regarding healthy behaviors.
Study: NCT01716468

Intervention type: OTHER
Group type: OTHER
Intervention: Ketogenic Diet
Description: modified ketogenic diet
Study: NCT01276665

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: restrictive intraoperative fluid substitution
Description: to analyze the impact of a restrictive volume regimen using advanced balanced electrolyte solution (which is by far more restrictive than the published data) combined with noradrenaline. We include only radical cystectomy and so nearly exclude surgical bias

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: assessment of the pelvic venous pressure
Description: A 20 G catheter will be introduced into a small collateral vein of the internal iliacal vein to monitor pelvic venous pressure
Study: NCT05329181

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Integrated cognitive behavioral treatment
Description: Integrated cognitive behavioral treatment adapted specifically for homeless individuals and developed to treat substance use and depressive symptoms simultaneously
Study: NCT03803852

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraocular Lens Implantation
Description: Implantation of an intraocular lens Rayner RayOne or Hoya Nanex or Hoya Vivinex Impressinto the capsular bag using an injector, after removing of the human cristalline lens.~Implantation of the Alcon Clareon toric and Rayner RayOne EMV toric IOL on the axis according to the steep meridian of the cornea

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraocular Lens Implantation
Description: Implantation of an intraocular lens Rayner RayOne or Hoya Nanex or Hoya Vivinex Impressinto the capsular bag using an injector, after removing of the human cristalline lens.~Implantation of the Alcon Clareon toric and Rayner RayOne EMV toric IOL on the axis according to the steep meridian of the cornea
Study: NCT02706184

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E. coli Nissle suspension
Description: Patients receive E. coli Nissle suspension

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study: NCT02530359

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pirfenidone extended release
Description: Pirfenidone extended release 600mg per mouth

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pirfenidone extended release
Description: Pirfenidone extended release 600mg per mouth
Study: NCT01933191

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic treadmill exercise
Description: Experimental training: Aerobic treadmill exercise (30 minutes, 70% VO2max) prior to an elective minor dental procedures (e.g., extractions, endodontics, apicoectomies, dental restorations, periodontal treatment, dental implants).

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Aerobic treadmill exercise
Description: Experimental training: Aerobic treadmill exercise (30 minutes, 70% VO2max) prior to an elective minor dental procedures (e.g., extractions, endodontics, apicoectomies, dental restorations, periodontal treatment, dental implants).

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: placebo exercise
Description: placebo exercise: Aerobic treadmill exercise (30 minutes, 20% VO2max) prior to an elective minor dental procedures (e.g., extractions, endodontics, apicoectomies, dental restorations, periodontal treatment, dental implants).

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo exercise
Description: placebo exercise: Aerobic treadmill exercise (30 minutes, 20% VO2max) prior to an elective minor dental procedures (e.g., extractions, endodontics, apicoectomies, dental restorations, periodontal treatment, dental implants).
Study: NCT02742922

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally adapted therapy (C-MAP)
Description: C-MAP is a brief problem focused therapy, comprising of six sessions delivered within three months. C-MAP is a manual assisted intervention based on the principles of CBT .In this intervention there is an evaluation of the self-harm attempt, crisis skills, problem solving and basic cognitive techniques to manage emotions, negative thinking and relapse prevention strategies.
Study: NCT03928834

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adapted Nzira Itsva
Description: Adolescents will be provided an enhanced adherence package consisting of VL testing using DBS, including the NI intervention and low-cost genotyping and drug resistance monitoring. Participants receiving the intervention will have their first session after recruitment and enrollment, and will schedule up to 4 additional booster sessions at a time convenient for them spaced approximately 1 month apart. This may be modified after the formative assessment.