Study: NCT02479412

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 250 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 250 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 250 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 250 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 58 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 58 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 58 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 58 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 58 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 58 µg AZD7594 once daily
Description: Once daily dosing of 800 µg AZD7594 for 14 days; each dose of AZD7594 inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo once daily
Description: Once daily dosing of Placebo to AZD7594 for 14 days; each dose of Placebo inhalation powder will be administered via a dry powder monodose inhaler as 2 hard capsules with 2 inhalations per capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salbutamol
Description: Inhalation as needed