Study: NCT00262470

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetazolamide
Description: 250 mg PO x 1

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atomoxetine
Description: 10-40 mg PO x 1 dose

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NO Drug
Description: No intervention - just monitoring

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clonidine
Description: Clonidine 0.05-0.3 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Entacapone
Description: Entacapone 200-400 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Entacapone & Propranolol
Description: Entacapone 200-400 mg PO x 1 dose AND propranolol 20 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Entacapone & Propranolol
Description: Entacapone 200-400 mg PO x 1 dose AND propranolol 20 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atomoxetine & Propranolol
Description: Atomoxetine 10-40 mg PO x 1 dose AND propranolol 20 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atomoxetine & Propranolol
Description: Atomoxetine 10-40 mg PO x 1 dose AND propranolol 20 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indomethacin
Description: Indomethacin 25-50 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mecamylamine
Description: mecamylamine 1.25-5 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Isosorbide Dinitrate
Description: Isosorbide dinitrate 5-20 mg PO x 1 dose

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Melatonin
Description: melatonin 3 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midodrine
Description: midodrine 2.5-10 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modafinil
Description: modafinil 100-200 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Octreotide
Description: octreotide 12.5-50 mcg Subcutaneous x 1 dose

Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: lactose tablet x 1 pill

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Propranolol 10-80 mg PO x 1-2 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modafinil & Propranolol
Description: Modafinil 100-200 mg PO x 1 dose AND Propranolol 20 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modafinil & Propranolol
Description: Modafinil 100-200 mg PO x 1 dose AND Propranolol 20 mg PO x 1 dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sertraline
Description: sertraline 25-50 mg PO x 1 dose

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IV Saline
Description: 1 liter IV over 2 hours

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Drinking Water
Description: 16 fluid ounces

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Breathing Device
Description: Breathing through a dead space tube

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: memantine
Description: memantine 5-20 mg PO x 1 dose

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Abdominal binder
Description: Using large blood pressure cuffs linked together, they are wrapped around the subjects abdomen and inflated to generate increased pressure to below tolerably threshold.