Study: NCT02971228

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Lispro
Description: Used to lower blood glucose. Commercially available by prescription and is indicated for patients with type 1 diabetes mellitus (T1DM), but not for use in a bionic pancreas. Individualized dose based on metabolic needs and frequent monitoring of blood glucose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Lispro
Description: Used to lower blood glucose. Commercially available by prescription and is indicated for patients with type 1 diabetes mellitus (T1DM), but not for use in a bionic pancreas. Individualized dose based on metabolic needs and frequent monitoring of blood glucose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Lispro
Description: Used to lower blood glucose. Commercially available by prescription and is indicated for patients with type 1 diabetes mellitus (T1DM), but not for use in a bionic pancreas. Individualized dose based on metabolic needs and frequent monitoring of blood glucose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Lispro
Description: Used to lower blood glucose. Commercially available by prescription and is indicated for patients with type 1 diabetes mellitus (T1DM), but not for use in a bionic pancreas. Individualized dose based on metabolic needs and frequent monitoring of blood glucose.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZP4207 (dasiglucagon)
Description: A glucagon analog not yet approved by the FDA. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZP4207 (dasiglucagon)
Description: A glucagon analog not yet approved by the FDA. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZP4207 (dasiglucagon)
Description: A glucagon analog not yet approved by the FDA. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZP4207 (dasiglucagon)
Description: A glucagon analog not yet approved by the FDA. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucagon
Description: A hormone normally made by the pancreas to raise blood glucose. Used to treat low blood sugar. Commercially available by prescription and is indicated for patients with T1DM in severe hypoglycemia, but not for use in a BP. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucagon
Description: A hormone normally made by the pancreas to raise blood glucose. Used to treat low blood sugar. Commercially available by prescription and is indicated for patients with T1DM in severe hypoglycemia, but not for use in a BP. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucagon
Description: A hormone normally made by the pancreas to raise blood glucose. Used to treat low blood sugar. Commercially available by prescription and is indicated for patients with T1DM in severe hypoglycemia, but not for use in a BP. Subcutaneous administration in one BP arm.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucagon
Description: A hormone normally made by the pancreas to raise blood glucose. Used to treat low blood sugar. Commercially available by prescription and is indicated for patients with T1DM in severe hypoglycemia, but not for use in a BP. Subcutaneous administration in one BP arm.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iPhone-based bionic pancreas
Description: An experimental device.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iPhone-based bionic pancreas
Description: An experimental device.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iLet-based bionic pancreas
Description: An experimental device.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iLet-based bionic pancreas
Description: An experimental device.