TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT05111028

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Autologous Room Temperature stored Platelet transfusion
Description: An autologous transfusion of platelets stored at 22°C for 7 days.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Room Temperature stored Platelet transfusion
Description: An autologous transfusion of platelets stored at 22°C for 7 days.

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Autologous Cold Stored Platelet transfusion
Description: An autologous transfusion of platelets stored at 4°C for 7, 14, 21, or 28 days.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous Cold Stored Platelet transfusion
Description: An autologous transfusion of platelets stored at 4°C for 7, 14, 21, or 28 days.
Study: NCT02822261

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Coppertone (BAY987516)
Description: Each 50 cm\*2 test site area of a subject requires 100 mg of a test material to obtain a standard 2 mg/cm\*2 test application. (Formulation: SR15-66_R84-088)
Study: NCT03900273

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No Practice Effects (NPE) cognitive battery, and Miami Computerized Functional Assessment Scale (CFAS)
Description: Novel measures of Cognitive and Everyday function

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preclinical Alzheimer's Cognitive Composite (PACC), Alzheimer's Disease Assessment Scale-Cognitive Scale (ADAS-Cog), and Functional Assessment Questionnaire (FAQ)
Description: Established measures of Cognitive and Everyday Function
Study: NCT04354883

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: External Chest Compressions on Manikin in Underwater Setting
Description: Two different methods of CPR in an analogue model of mircogravity

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: External Chest Compressions on Manikin in Underwater Setting
Description: Two different methods of CPR in an analogue model of mircogravity
Study: NCT01745042

Intervention type: OTHER
Intervention: Clinical exams
Description: Physiological and biochemical tests; quality of life questionnaire; body composition measurement

Intervention type: OTHER
Intervention: Clinical exams
Description: Physiological and biochemical tests; quality of life questionnaire; body composition measurement
Study: NCT01122849

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Prototype Nasal Dilator
Description: Prototype nasal dilator AB2R11

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Marketed Nasal Strip
Description: Breathe Right Nasal Strip- Clear small/medium

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Nasal Strip
Description: Placebo strip
Study: NCT01569048

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol and dexmedetomidine
Description: Both group : propofol effect site TCI 2-4 mcg/ml, Remifentanil group : remifentanil effect site-TCI 2-4ng/ml Dexmedetomidine group: dexmedetomidine 0.5mcg/kg loading and 0.5mcg/kg/hr infusion

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: propofol and remifentanil
Description: Both group : propofol effect site TCI 2-4 mcg/ml, Remifentanil group : remifentanil effect site-TCI 2-4ng/ml Dexmedetomidine group: dexmedetomidine 0.5mcg/kg loading and 0.5mcg/kg/hr infusion
Study: NCT01846741

Intervention type: DEVICE
Group type: OTHER
Intervention: M106 VNS Therapy System
Study: NCT01853878

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant PRAME protein combined with the AS15 Adjuvant System GSK2302032A
Description: Intramuscular administration

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intramuscular administration
Study: NCT04020497

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Ensemble programme
Description: Ensemble is a individualized programme to address informal caregiver's specific unmet needs, emotions and social resources, in order to offer a targeted support in five sessions.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SAU
Description: Informal caregivers have often to manage the situation in usual different ways. Support as usual (SAU) alone consists of an informal support by patient's clinical team. Specific psychoeducational programs depending on patient's illnes (like Profamille for schizophrenia) or peer-support depending to the voluntary work of families' associations. Some general professional services focused on informal caregivers or relatives in order to inform and orient them if they are avaible in the study area. No attempts have been made to standardize this treatement as SAU depend to informal caregiver's need and knowledge of the health system, also her/his capacity or possibility to be in contact with patient's clinical team.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SAU
Description: Informal caregivers have often to manage the situation in usual different ways. Support as usual (SAU) alone consists of an informal support by patient's clinical team. Specific psychoeducational programs depending on patient's illnes (like Profamille for schizophrenia) or peer-support depending to the voluntary work of families' associations. Some general professional services focused on informal caregivers or relatives in order to inform and orient them if they are avaible in the study area. No attempts have been made to standardize this treatement as SAU depend to informal caregiver's need and knowledge of the health system, also her/his capacity or possibility to be in contact with patient's clinical team.
Study: NCT01678612

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Copper-alloy surfaced objects
Description: Room assigned to the Experimental arm will be furnished with copper-alloy surfaced objects,i.e. bed-rails, bed-rail levers, IV poles, nurse workstation, HCW clipboards, sink handles.
Study: NCT03779815

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]Florbetaben
Description: * Drug: \[18F\]Florbetaben~* \[18F\]Florbetaben PET/CT Imaging for detecting amyloidosis in multiple myeloma~* Other name: Neuraceq~* Amount: 300 MBq ± 20% bolus, 10mL intravenously
Study: NCT00516867

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: UV radiation
Description: UV radiation with 99.5% UVA and 0.5%UVB

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: UV radiation
Description: UVB 1.4 % and UVA 98.6
Study: NCT00902707

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mucinex 1200mg
Description: Compared to Placebo

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Compare to active Mucinex
Study: NCT02474407

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: diazepam nasal spray

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: diazepam rectal gel
Study: NCT05862311

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ELISA
Description: ELISA(enzyme-linked immunosorbent assay)

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ELISA
Description: ELISA(enzyme-linked immunosorbent assay)
Study: NCT04584957

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: VAC therapy
Description: Prophylactic ciNPWT therapy (Prevena® KCI) entails placement of the device over a closed incision immediately post-operatively. Prevena® KCI may be left in place with no additional intervention for up to 7 days.
Study: NCT01210586

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Part 2
Description: Comparing smoking symptomatology by HRT and nicotine patch status using a 2x2 randomized design.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Part 2
Description: Comparing smoking symptomatology by HRT and nicotine patch status using a 2x2 randomized design.
Study: NCT01036932

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Granulocyte Colony Stimulating Factor
Description: Dose of 5 µg/kg s/c at days 1, 2, 3, 4, 5, and then every 3rd day till day 28 (total 12 doses) along with the standard therapy.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: dose of 1ml s/c at days 1, 2, 3, 4, 5, and then every 3rd day till day 28 (total 12 doses) along with the standard therapy.
Study: NCT01145326

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: 4% lidocaine gel application with sham microneedle device
Description: Topical 4% lidocaine gel (LG4) applied to subject, after application of sham microneedle device (FMA).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microneedle-facilitated lidocaine application
Description: Application of 4% lidocaine gel (LG4), after application of microneedle (FMA) device
Study: NCT03861624

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intramedullary nailing with standard SIGN nail
Description: Patients meeting eligibility requirements are randomized to either study arm. Patients receive definitive fixation of AO/OTA-42 open tibia diaphyseal fractures using the standard SIGN nail (SIGN Fracture Care International, Richland, WA). The number of interlocking screws is at the discretion of the treating surgeon, who also has the option to use an external fixator for damage control, and later conversion to IMN when clinically appropriate. The experimental group procedure is less common in the study setting, and thus, viewed as the experimental group.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: External Fixation with uniplanar Dispofix external fixator
Description: Patients meeting eligibility requirements are randomized to either study arm. Patients receive definitive fixation of AO/OTA-42 open tibia diaphyseal fractures using the uniplanar Dispofix external fixator with two Shanz screws placed proximally and two Schanz screws placed distally to fracture site with a single stainless steel bar.The active comparator group procedure is more common in the study setting, and thus, viewed as the comparator group.
Study: NCT03408015

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lifitegrast
Description: Lifitegrast ophthalmic solution, 5.0%. 1 drop instilled into each eye once in the morning and once before bed.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lifitegrast
Description: Lifitegrast ophthalmic solution, 5.0%. 1 drop instilled into each eye once in the morning and once before bed.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lifitegrast
Description: Lifitegrast ophthalmic solution, 5.0%. 1 drop instilled into each eye once in the morning and once before bed.
Study: NCT02086669

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pneumatic dilatation

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic myotomy
Study: NCT01530321

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation
Description: 5 minutes of high velocity, low amplitude thrust to cervical and upper thoracic spine.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation
Description: 5 minutes of high velocity, low amplitude thrust to cervical and upper thoracic spine.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation
Description: 5 minutes of high velocity, low amplitude thrust to cervical and upper thoracic spine.
Study: NCT01923870

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Androxal 25 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Androxal 25 mg
Study: NCT04618653

Intervention type: OTHER
Intervention: assessment only
Description: Three assessment will include computerized assessments, interviews, and subset will provide daily reports of prescribed AA behaviors and practices
Study: NCT01530321

Intervention type: OTHER
Group type: OTHER
Intervention: Light Massage
Description: 5 minutes of light pressure massage to the neck and upper back

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Light Massage
Description: 5 minutes of light pressure massage to the neck and upper back

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Light Massage
Description: 5 minutes of light pressure massage to the neck and upper back
Study: NCT01188603

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: flibanserin 100 mg dose every evening
Description: all subjects receive flibanserin
Study: NCT04750837

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: debridement of the wound
Description: The edges and the floor of the wound were firstly debrided, and any callosities around the wound were removed. This was repeated if needed when callosities around the wound reappeared. By this technique, the chronic wound was transformed into an acute one

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: debridement of the wound
Description: The edges and the floor of the wound were firstly debrided, and any callosities around the wound were removed. This was repeated if needed when callosities around the wound reappeared. By this technique, the chronic wound was transformed into an acute one

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: platelet rich plasma
Description: Part of activated PRP was injected around the wound and under the base of the wound, while another portion of PRP was left over the floor of the wound and let to coagulate and form a gel.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional dressing
Description: The wound was irrigated by normal saline, covered by vaseline gauze then sterile dressing. Repeated dressing every two days till 20 weeks, if the wound failed to heal at that time

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: conventional dressing
Description: The wound was irrigated by normal saline, covered by vaseline gauze then sterile dressing. Repeated dressing every two days till 20 weeks, if the wound failed to heal at that time
Study: NCT02572466

Intervention type: OTHER
Intervention: Hemodialysis
Description: ESRD group received long-term hemodialysis
Study: NCT03323658

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bexarotene
Description: Given topically

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study: NCT00363454

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triciribine Phosphate Monohydrate
Description: 8 Cycles @ 28 days. Level 1: 15 mg/m\^2; Level 2: 25 mg/m\^2; 35 mg/m\^2; 45 mg/m\^2.
Study: NCT00881192

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: IABP
Description: preoperative IABP placement
Study: NCT04300569

Intervention type: OTHER
Intervention: Non-interventional
Description: No intervention will be administered.
Study: NCT01005004

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HuCNS-SC cells
Description: intracerebral transplantation
Study: NCT01132495

Intervention type: OTHER
Group type: OTHER
Intervention: Stenting plus OMT
Description: FFR guided PCI, plus OMT
Study: NCT03947073

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: Three cartoon illustrated educational videos with information on gestational diabetes will be provided to the patient in addition to standard of care.
Study: NCT01132495

Intervention type: OTHER
Group type: OTHER
Intervention: OMT
Description: OMT alone

Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care
Description: FFR \> 0.80; treatment according to local practice
Study: NCT04152967

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: new-designed PTFE valved conduits
Description: In this prospective comparative research, all patients will be divided into two groups randomly with 100 patients in each group. One group will use the new-designed PTFE valved conduits and another one will implant the bovine jugular vein valved conduits.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bovine jugular vein valved conduits
Description: In this prospective comparative research, all patients will be divided into two groups randomly with 100 patients in each group. One group will use the new-designed PTFE valved conduits and another one will implant the bovine jugular vein valved conduits.
Study: NCT01860235

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EMLA
Description: % eutectic mixture of 25mg/g lidocaine and 25 mg/g of prilocaine

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Injectable anesthesia
Description: Injectable anesthesia 2% lidocaine with epinephrine 1:100.000

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2% Benzocaine
Description: Topical anesthetic - 200mg/g of 2% benzocaine
Study: NCT01876485

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empowering Patients in Chronic Care (EPIC)
Description: EPIC group training sessions consisting of 6 one-hour group sessions occurring over a 6-month period. Group sessions will consist of behavioral coaching focused on diabetes management. Following each group-session, patients enrolled in the intervention arm will meet with a designated member of their primary care team to personalize diabetes goals and action plans.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care (EUC)
Description: Patients randomized to EUC will be referred to the PACT RN Care Manager for diabetes management, and will also receive a packet of educational materials regarding diabetes management, including a letter delineating the diabetes management resources available at their facility.
Study: NCT02800330

Intervention type: DRUG
Group type: OTHER
Intervention: Esomeprazole 40mg concomitantly
Description: During phase B the patients will use esomeprazole 40mg concomitantly with regorafenib for 5 days.

Intervention type: DRUG
Group type: OTHER
Intervention: Esomeprazole 40mg concomitantly
Description: During phase B the patients will use esomeprazole 40mg concomitantly with regorafenib for 5 days.

Intervention type: DRUG
Group type: OTHER
Intervention: Esomeprazole 40mg before
Description: During phase C the patients will use esomeprazole 40mg 3 hours before regorafenib for 5 days.

Intervention type: DRUG
Group type: OTHER
Intervention: Esomeprazole 40mg before
Description: During phase C the patients will use esomeprazole 40mg 3 hours before regorafenib for 5 days.

Intervention type: DRUG
Group type: OTHER
Intervention: Regorafenib 160mg or 120mg
Description: Patients will use regorafenib 160mg or 120mg during all phases (A, B, C)

Intervention type: DRUG
Group type: OTHER
Intervention: Regorafenib 160mg or 120mg
Description: Patients will use regorafenib 160mg or 120mg during all phases (A, B, C)
Study: NCT01074528

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mindfulness based stress reduction program
Description: 8-week mindfulness training program
Study: NCT03259126

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SCUT
Description: Two different home made curtains were attached to the angiographic table
Study: NCT01887002

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-2952
Description: ONO-2952 Active tablets, every day for 2 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo comparator
Description: ONO-2952 Matching Placebo every day for 2 weeks
Study: NCT03012035

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: positive treatment expectations
Description: Before participants undergo the exposure training their expectation of treatment efficacy is manipulated with different information regarding the following treatment. The experimental group will get positive treatment expectations induced with the accurate information, that exposure training refers to the gold standard in psychotherapy to reduce spider fear (= open administration of treatment).

Intervention type: OTHER
Group type: OTHER
Intervention: neutral treatment expectations
Description: The comparator group will get neutral expectations regarding treatment outcome. To induce neutral treatment expectations about the following exposure training, it is necessary to tell them they are in the comparator group and that they will receive a comparator condition exposure training for diagnostic purposes only (= hidden administration of treatment).
Study: NCT02805075

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fructooligosaccharide
Description: Given PO

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laboratory Biomarker Analysis
Description: Correlative studies
Study: NCT00916318

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Obesity-Children
Description: (A) internet based information and communication tool Sundabarn.se(B) psychologist directed seminars with different themes, giving parents tools to implement necessary changes in family-patterns and life style, combined with A, (C) occupational therapist directed group-treatment intended to help parents alter their daily life patterns and, combined with A, (D) control group.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Obesity-Children
Description: (A) internet based information and communication tool Sundabarn.se(B) psychologist directed seminars with different themes, giving parents tools to implement necessary changes in family-patterns and life style, combined with A, (C) occupational therapist directed group-treatment intended to help parents alter their daily life patterns and, combined with A, (D) control group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Obesity-Children
Description: (A) internet based information and communication tool Sundabarn.se(B) psychologist directed seminars with different themes, giving parents tools to implement necessary changes in family-patterns and life style, combined with A, (C) occupational therapist directed group-treatment intended to help parents alter their daily life patterns and, combined with A, (D) control group.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Obesity-Children
Description: (A) internet based information and communication tool Sundabarn.se(B) psychologist directed seminars with different themes, giving parents tools to implement necessary changes in family-patterns and life style, combined with A, (C) occupational therapist directed group-treatment intended to help parents alter their daily life patterns and, combined with A, (D) control group.
Study: NCT03230981

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optical imaging of the cornea in healthy subjects
Description: OCT vibrography and Brillouin microscopy