Study: NCT02390063

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.5T4
Description: A recombinant simian adenovirus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.5T4
Description: A recombinant simian adenovirus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.5T4
Description: A recombinant simian adenovirus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.5T4
Description: A recombinant simian adenovirus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.5T4
Description: A recombinant simian adenovirus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAdOx1.5T4
Description: A recombinant simian adenovirus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: MVA.5T4
Description: A recombinant replication deficient Modified Vaccinia Ankara virus encoding human tumour-associated antigen 5T4

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Metronomic cyclophosphamide (50mg bd)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Metronomic cyclophosphamide (50mg bd)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Metronomic cyclophosphamide (50mg bd)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide
Description: Metronomic cyclophosphamide (50mg bd)