Study: NCT03766399

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD0449
Description: Participants will receive single inhaled AZD0449 nebulizer suspension and single IV dose of AZD0449 solution.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive single dose of placebo for AZD0449 (nebulizer suspension).