TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT01454557

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auditory Stimuli
Description: Auditory Stimuli during rest and during physical activity

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auditory Stimuli
Description: Auditory Stimuli during rest and during physical activity
Study: NCT04086615

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NMES and exercise supplemented with high BFR
Description: The BFR-NMES-Exercise training consists of 20-min sessions performed concurrently with NMES and exercise in the clinic 2x a week for a total of 18 in-clinic sessions. Using the Delfi PTS Personalized Tourniquet System for Blood Flow Restriction at 80% of LOP, the participant performs 4 exercise sets of 60 repetitions (5 seconds ea) for 5 minutes, with a 1-minute BFR deflation between sets. The standard exercise rehabilitation protocol for PFPS combines open chain and closed chain quadriceps strengthening exercises: active straight leg raises, quadriceps straightening, step up, and squats. NMES training consists of 20-minute sessions: a 2-min warm-up, 15-min work-out, and a 3-min cool down using the KneeHAB® XP Multipath stimulation system which changes the current pathways between the electrodes for preset periods within each pulse, allowing for higher stimulation intensities that maximizes muscle fibre recruitment and minimizes muscle fatigue.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: NMES and exercise supplemented with low BFR
Description: The BFR-NMES-Exercise training consists of 20-min sessions performed concurrently with NMES and exercise in the clinic 2x a week for a total of 18 in-clinic sessions. Using the Delfi PTS Personalized Tourniquet System for Blood Flow Restriction at 20mmHG venous pressure (no blood flow restricted), the participant performs 4 exercise sets of 60 repetitions (5 seconds ea) for 5 minutes, with a 1-minute BFR deflation between sets. The standard exercise rehabilitation protocol for PFPS combines open chain and closed chain quadriceps strengthening exercises: active straight leg raises, quadriceps straightening, step up, and squats. NMES training consists of 20-minute sessions: a 2-min warm-up, 15-min work-out, and a 3-min cool down using the KneeHAB® XP Multipath stimulation system which changes the current pathways between the electrodes for preset periods within each pulse, allowing for higher stimulation intensities that maximizes muscle fibre recruitment and minimizes muscle fatigue.
Study: NCT03622931

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard chemotherapy
Description: Chemotherapy

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Standard chemotherapy
Description: Chemotherapy

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Romiplostim

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebos
Study: NCT02282033

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The Moderato System
Description: The BackBeat Moderato System incorporates traditional pacing modes and algorithms to provide pacing support to patients with all conditions currently indicated for dual chamber pacing. In addition, a special pacing algorithm was developed to reduce blood pressure.
Study: NCT00311168

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intervention/treatment
Description: Device: VIP On~Device: VIP Off

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intervention/treatment
Description: Device: VIP On~Device: VIP Off
Study: NCT02192697

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP8273
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP8273
Description: Oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ASP8273
Description: Oral administration
Study: NCT01426451

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group tutoring program
Description: Academic in-class intervention that focuses on differentiated academic instruction and improved overall academic adjustment. In each classroom assigned to the tutorship intervention, two academic resource assistants will provide weekly in-class support to students for the same length of time than the drama workshop (75 minutes, once a week), with the teacher present in the classroom.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Theatre workshops
Description: The theatre expression workshops will run for 12 weeks, with one 75-minute workshop per week. They will be incorporated into the regular class timetable and will be run by the two members of the intervention team who have training in theatre and psychology, and the homeroom teacher, whose level of direct involvement will increase gradually as he or she becomes familiar with the workshops.
Study: NCT04268966

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brincidofovir
Study: NCT03248804

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Soy group

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Non-soy group
Study: NCT04267315

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Trigger point injection
Description: 1mL injections of 1% lidocaine in the muscles identified active trigger points at the day of intervention (pectoralis major, serratus anterior, levator scapulae, latissimus dorsi, infraspinatus).

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Subcutaneous saline injection
Description: 0.2mL subcutaneous saline injections superficial to the muscles identified with active trigger points at the day of intervention (pectoralis major, serratus anterior, levator scapulae, latissimus dorsi, infraspinatus).

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Comprehensive Rehabilitation program
Description: Patients in both groups will undergo standard of care rehabilitation delivered by a Physiatrist, which may include Physical Therapy, Occupational Therapy, Exercise Physiologist, Rehabilitation Nurse, Psychologist, as per Physiatrist's prescription. Both the comprehensive rehabilitation program and pain medications will continue to be managed by participant's Physiatrist, who will be blinded to patient's allocation. The researchers will be responsible for TPI and for data collection.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Comprehensive Rehabilitation program
Description: Patients in both groups will undergo standard of care rehabilitation delivered by a Physiatrist, which may include Physical Therapy, Occupational Therapy, Exercise Physiologist, Rehabilitation Nurse, Psychologist, as per Physiatrist's prescription. Both the comprehensive rehabilitation program and pain medications will continue to be managed by participant's Physiatrist, who will be blinded to patient's allocation. The researchers will be responsible for TPI and for data collection.
Study: NCT02346422

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: MYDICAR Phase 1
Description: Single dose of MYDICAR

Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: MYDICAR Phase 2
Description: Single dose of MYDICAR

Intervention type: GENETIC
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Phase 2 only
Description: Single dose of placebo
Study: NCT04342585

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Micronised vaginal progesterone
Description: A diary will be given to participants to ensure compliance.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal pessary
Description: The internal diameter size will be decided based on the clinical assessment of the cervix.
Study: NCT03888079

Intervention type: DRUG
Intervention: Local anesthetic
Description: 1% or 2% lidocaine with 1:100,000 epinephrine, augmented by intravenous sedation and analgesia

Intervention type: DRUG
Intervention: general anesthetic
Description: Endotracheal intubation, intravenous narcotic agents, and inhaled agents
Study: NCT03238872

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Study: NCT01945242

Intervention type: DRUG
Intervention: Alogliptin
Description: Alogliptin tablets
Study: NCT02813720

Intervention type: RADIATION
Intervention: HR-pQCT High resolution peripheral quantitative CT-scan
Description: HR-pQCT is a powerful device providing low dose irradiation already used in bone field.~It is a high resolution tool (voxel size=82µm) that the investigators adapted to look after the distal joint involved by onycholysis. An anteroposterior scout view is used to define the region of interest (ROI), which spanned from the top of the distal phalange to the distal part of the intermediate phalange in order to contain the distal joint of the target finger. Images are then analysed for erosions, osteophytes and volumetric bone mineral density.

Intervention type: RADIATION
Intervention: HR-pQCT High resolution peripheral quantitative CT-scan
Description: HR-pQCT is a powerful device providing low dose irradiation already used in bone field.~It is a high resolution tool (voxel size=82µm) that the investigators adapted to look after the distal joint involved by onycholysis. An anteroposterior scout view is used to define the region of interest (ROI), which spanned from the top of the distal phalange to the distal part of the intermediate phalange in order to contain the distal joint of the target finger. Images are then analysed for erosions, osteophytes and volumetric bone mineral density.

Intervention type: RADIATION
Intervention: HR-pQCT High resolution peripheral quantitative CT-scan
Description: HR-pQCT is a powerful device providing low dose irradiation already used in bone field.~It is a high resolution tool (voxel size=82µm) that the investigators adapted to look after the distal joint involved by onycholysis. An anteroposterior scout view is used to define the region of interest (ROI), which spanned from the top of the distal phalange to the distal part of the intermediate phalange in order to contain the distal joint of the target finger. Images are then analysed for erosions, osteophytes and volumetric bone mineral density.

Intervention type: RADIATION
Intervention: HR-pQCT High resolution peripheral quantitative CT-scan
Description: HR-pQCT is a powerful device providing low dose irradiation already used in bone field.~It is a high resolution tool (voxel size=82µm) that the investigators adapted to look after the distal joint involved by onycholysis. An anteroposterior scout view is used to define the region of interest (ROI), which spanned from the top of the distal phalange to the distal part of the intermediate phalange in order to contain the distal joint of the target finger. Images are then analysed for erosions, osteophytes and volumetric bone mineral density.
Study: NCT02318277

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MEDI4736
Description: MEDI4736 administered intravenously (IV) every two weeks (q2w)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB024360
Description: INCB024360: Oral daily dosing
Study: NCT04107363

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Oropharyngeal aspiration before changing the position of the patient
Description: Patients in the experimental group underwent oropharyngeal aspiration prior to each position change in addition to routine nursing care (Endotracheal aspiration in case of indication and oropharyngeal aspiration in the follow-up; routine and non-routine position changes every 2 hours during the day and 4 hours during the night; oral care).~Patients in this group underwent oropharyngeal aspiration at least 9 times in 24 hours with a pressure of 100-120 mmHg for 10 seconds prior to routine (2 hours a day, 4 hours a night) and non-routine position changes. After the oropharyngeal aspiration was completed, the patient's position was changed.

Intervention type: OTHER
Group type: OTHER
Intervention: Control group:
Description: The patients in the control group received routine nursing care in the unit. (Endotracheal aspiration in case of indication and oropharyngeal aspiration in the follow-up; routine and non-routine position changes every 2 hours during the day and 4 hours during the night; oral care).
Study: NCT01475500

Intervention type: PROCEDURE
Intervention: Sputum sample
Description: This is a collection of sputum (mucous) you cough up. Three morning samples will be collected at one time. Sputum will be collected at baseline, year 1, year 2 and year 5.
Study: NCT05016180

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ropivacaine
Description: Before the induction of anesthesia, ropivacaine is used for bilateral transversus abdominis plane block in a volume of 20 mL of each side

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine
Description: Before the induction of anesthesia, ropivacaine is used for bilateral transversus abdominis plane block in a volume of 20 mL of each side
Study: NCT01475500

Intervention type: PROCEDURE
Intervention: Pulmonary function tests
Description: A series of different breathing tests designed to measure lung function and to determine the presence or absence of chronic obstructive pulmonary disease will be performed at baseline.

Intervention type: RADIATION
Intervention: Computerized tomography (CT) scan of the chest
Description: A CT scan uses x-rays to take detailed pictures of the chest. Performed at baseline, year 2 and year 5. If nodules are present, CT scans will be performed every 3 months for the first year of the study.

Intervention type: OTHER
Intervention: Buccal epithelium collection
Description: Collect cells from the inside of the cheek. Samples will be collected at baseline and yearly to year 5.

Intervention type: PROCEDURE
Intervention: Nasal brushings
Description: A cytobrush is used to remove cells on the surface of the inside of the nose. Samples will be collected at baseline and yearly to year 5.

Intervention type: PROCEDURE
Intervention: Bronchoscopy
Description: A flexible tube with a light and a camera will be inserted through the nose or mouth, and into the lungs to look at the airway. Bronchial tissue will be obtained.

Intervention type: PROCEDURE
Intervention: Bronchoalveolar lavage
Description: During a bronchoscopy, a flexible tube with a light and a camera is passed through the mouth or nose into the lungs and fluid is squirted into a small part of the lung and collected for examination. Bronchoscopies will be performed at baseline and at year 5.

Intervention type: PROCEDURE
Intervention: Blood sample collection
Description: A venous blood sample will be collected for testing of biomarkers and other relevant tests. Blood will be taken at baseline and yearly to year 5.

Intervention type: PROCEDURE
Intervention: Urine sample
Description: Urine will be collected for routine urine tests at baseline and yearly to year 5.

Intervention type: PROCEDURE
Intervention: Questionnaire-data collection
Description: A questionnaire about the patient's health, medical, and smoking history. Administered at baseline and yearly to year 5. Data will be taken from patient interviews and from the medical record.
Study: NCT04599257

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-899
Description: The device applicator combines high-intensity focused electromagnetic procedure and radiofrequency energy to induce visible muscle contractions along with heating of the subcutaneous fat.
Study: NCT01118598

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: tredaptive (nicotinic acid/ laropiprant)
Description: tablet of nicotinic acid 1000 mg/laropiprant 20 mg one tablet of for 4 weeks followed by two tablets od for 8 weeks

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo tablet one a day for first 4 weeks followed by two a day for 8 weeks
Study: NCT00585286

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 10,600 nm fractional carbon dioxide laser system
Description: 1-3 laser treatments using 20-100 millijoules (mJ) with 100-400 microscopic treatment zones (MTZ)/cm2 per pass and total density of 600-1200 MTZ/cm2
Study: NCT00967135

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pregabalin
Description: 150 mg oral dose of pregabalin twice daily for 5 consecutive days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching oral placebo twice daily for 5 consecutive days.
Study: NCT02502071

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sodium bicarbonate
Description: All participants will receive 2 doses of 1950mg sodium bicarbonate
Study: NCT02571244

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interview plus text message
Description: After discharge the experimental group has received extended care including a counseling session and text messages. The session provided basic information about smoking and successful quitting. The counselor has used motivational interview techniques to build coping skills with the goal of helping the participant build and implement a quit plan. The focus was to increase motivation to make quit attempt, including confidence building, medication use, and cessation planning. The session lasted approximately 30 minutes. Participants in the experimental arm were offered up to 30 text messages to help them to implement the quit plan discussed during the phone call. Patients motivated to quit in the next 30 days or those that had already quit have received 30 messages (2 per day) and patients unwilling to quit 16 (2 per day). The messages followed the self efficacy theory.
Study: NCT02990143

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ologen
Description: Ologen® CM,a biodegradable scaffold matrix, induces a regenerative non-scarring wound healing process without using anti-fibrotic agents.
Study: NCT03640026

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Tacrolimus will be initiated at 0.1 mg/kg/day in two separate 12-hour oral doses (capsules) for 14 days.
Study: NCT01503957

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nasya
Description: Thixotropic nasal spray suspension, 2 sprays in each nostril

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Saline solution
Description: Nasal spray, 2 sprays in each nostril
Study: NCT01261039

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: UV radiation
Description: Subjects in both groups will be exposed to light in a solar bed for approximately 10 minutes (depending on Fitzpatrick skin type test) on the first day, but only one of the solar beds wields ultraviolet rays. The other has a filter, which filters out the ultraviolet rays.

Intervention type: RADIATION
Group type: SHAM_COMPARATOR
Intervention: UV radiation
Description: Subjects in both groups will be exposed to light in a solar bed for approximately 10 minutes (depending on Fitzpatrick skin type test) on the first day, but only one of the solar beds wields ultraviolet rays. The other has a filter, which filters out the ultraviolet rays.
Study: NCT04125186

Intervention type: DIAGNOSTIC_TEST
Intervention: Baseline EpiNP survey
Description: The survey takes approximately 20 to 30 minutes to complete, and consists of the following: Short Form Health Survey version 2.0 (SF-12v2.0); Lower Urinary Tract Symptoms (LUTS) Tool; Patient Perception of Bladder Condition (PPBC); Self-report Medical History and Current Medication Form; Nocturia Impact Diary (NID); Disease-Specific Healthcare-Seeking Behavior and Treatment; Epworth Sleepiness Questionnaire (ESS); Patient Reported Outcome Measurement Information System Fatigue-Short Form version 1.0 (PROMIS F-SFv1.0); Patient Health Questionnaire (PHQ-8); Work Productivity and Activity Index (WPAI-SHP); Sexual health questions; lifestyle and sociodemographic questions; additionally, only men will complete the International Prostate Symptom Score (IPSS).

Intervention type: DIAGNOSTIC_TEST
Intervention: Bladder diary
Description: It consists of four components: measurement of waist and neck circumference, daily voiding diary (to assess voiding patterns, including frequency, volume, associated urgency, and incontinence episodes over a 24-hour period), NID (to assess nocturia impact), and assessment of morning sleepiness for 3 consecutive days and nights (including the morning of the fourth day).

Intervention type: DIAGNOSTIC_TEST
Intervention: Testing of EpiNP baseline survey, bladder diary and a qualitative interview
Description: This part briefly reviews the usability of the EpiNP survey and bladder diary. The feedback obtained after qualitative interview will be used to refine and finalize the instructions sent to the participants in the main part.

Intervention type: OTHER
Intervention: No other intervention
Description: No other intervention

Intervention type: OTHER
Intervention: No other intervention
Description: No other intervention
Study: NCT03418753

Intervention type: DIAGNOSTIC_TEST
Intervention: EyeBOX for ICP
Description: non-invasive ICP Score algorithm using eye-tracking data from the EyeBOX(TM) device, which tracks the movement of the pupils over time
Study: NCT01075282

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin Glargine

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY2189265

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY2189265

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glimepiride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glimepiride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glimepiride
Study: NCT03899935

Intervention type: PROCEDURE
Intervention: Laparoscopy
Description: Laparoscopy for endometriosis

Intervention type: PROCEDURE
Intervention: Laparoscopy
Description: Laparoscopy for endometriosis
Study: NCT02630797

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Blueberry Baseline
Description: Before the study beginning, eligible participants will receive a radioactive tracer, Ca-41, by iv infusion. A total of 150 days will be required for the equilibration of tracer in the body i.e. elimination from soft tissue and deposition in the bone. After equilibration, a baseline period of 42 days will occur, during which no blueberry products will be provided.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Blueberry Low
Description: One food or beverage product containing freeze-dried blueberry powder equivalent to 0.75 cups of fresh blueberries will be provided daily for 42 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Blueberry Medium
Description: Two food or beverage products containing freeze-dried blueberry powder equivalent to 1.5 cups of fresh blueberries will be provided daily for 42 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Blueberry High
Description: Four food or beverage products containing freeze-dried blueberry powder equivalent to 3 cups of fresh blueberries will be provided daily for 42 days.