TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04468932

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: Aim 1: To determine the clinical effects of rTMS targeting the cerebellum on postural instability in PSP. The hypothesis to be tested is that TMS augmentation of cerebellar inhibition will improve cerebellum-dependent balance symptoms of PSP for a period of time sufficient to improve rehabilitation outcomes. The investigators will measure a battery of objective posturography metrics and other measures of motor control, including sway and center of pressure changes to backward tilt and forward translation.~Aim 2: We will use functional near infrared spectroscopy (fNIRS) to examine changes in motor and premotor cortical activity after cerebellar rTMS. The hypothesis to be tested is that premotor and motor cortical activity will decrease after cerebellar rTMS compared to sham TMS, reflecting improved cerebellar inhibition of the motor cortex after the intervention.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: Aim 1: To determine the clinical effects of rTMS targeting the cerebellum on postural instability in PSP. The hypothesis to be tested is that TMS augmentation of cerebellar inhibition will improve cerebellum-dependent balance symptoms of PSP for a period of time sufficient to improve rehabilitation outcomes. The investigators will measure a battery of objective posturography metrics and other measures of motor control, including sway and center of pressure changes to backward tilt and forward translation.~Aim 2: We will use functional near infrared spectroscopy (fNIRS) to examine changes in motor and premotor cortical activity after cerebellar rTMS. The hypothesis to be tested is that premotor and motor cortical activity will decrease after cerebellar rTMS compared to sham TMS, reflecting improved cerebellar inhibition of the motor cortex after the intervention.
Study: NCT03794037

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dydrgesterone 10 mg( tab)/12hs/14 days
Description: Dydrogesterone Oral Tablet 10 mg twice daily for 14 days to be taken from the day of ovum pickup

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: montelukast 10 mg(tab) oral/24hs/ 7 days dydrgesterone 10 mg( tab) oral/12hs/14 days
Description: montelukast 10 mg(tab) once daily oral for 7 days \& dydrgesterone 10 mg (tab) twice daily oral for 14 days \&
Study: NCT03499392

Intervention type: OTHER
Group type: OTHER
Intervention: psychological tests
Description: psychological tests psychological interviews
Study: NCT01889316

Intervention type: DEVICE
Group type: OTHER
Intervention: Novii
Description: The Novii is a modified device with similar technology to the AN24 device already being used in the USA.

Intervention type: DEVICE
Group type: OTHER
Intervention: AN24
Study: NCT03951922

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Horticultural activity
Description: Therapeutic horticulture activities are plant-related activities that include but not limited to digging, watering, planting, weeding, trimming, fertilizing, mulching, harvesting, learning about organic farming, and exploring options to incorporate horticulture into daily activities
Study: NCT01687894

Intervention type: DRUG
Intervention: propofol
Description: vasopressin propofol \& placebo propofol

Intervention type: DRUG
Intervention: propofol
Description: vasopressin propofol \& placebo propofol
Study: NCT03748199

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: POL6014
Description: DL1 80 mg cohorts 1A and 1B (80 mg QD and 40 mg BID) DL2 160 mg cohorts 2A and 2B (160 mg QD and 80 mg BID) DL3 40 mg QD cohort C~DL = dose Level QD= quaque die (once daily) BID= bis in die (twice daily)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered orally at a dose and frequency matched to POL6014
Study: NCT01162382

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Magnetic Stimulation
Description: Four 100-second trains and then one 65-second train, with 30-second inter-train intervals, at 1 Hz and 120% of the resting motor threshold will be applied over the right dorsolateral prefrontal cortex. Subsequently, twenty-five 30-second trains, with a 30-second inter-train interval, at 10 Hz and 120% of the resting motor threshold will be applied over the left dorsolateral prefrontal cortex.
Study: NCT00882258

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 12.5 mg Proellex
Description: 12.5 mg Proellex administered orally daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 25 mg Proellex
Description: 25 mg Proellex administered orally daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally daily
Study: NCT03718442

Intervention type: DEVICE
Intervention: PhotonBlade vs Bovie for lumpectomy shaved surgical margins
Description: For each enrolled patient, six shaved margins will be obtained (superior, inferior, medial, lateral, anterior, and posterior). For each patient, electrocautery will be used to obtain 3 of the shaved margins, and PhotonBlade to obtain the other 3 shaved margins. Once the lumpectomy site shaved margins have been obtained, the shaved surgical margins will be evaluated by a pathologist whom is blinded in regards to the dissection device that was used for each margin. The pathologist will be evaluating each shaved margin and reporting the outcomes (qualitative severity and depth of thermal artifact)
Study: NCT02678676

Intervention type: OTHER
Intervention: No Intervention
Description: Participants who previously received Pioglitazone in the PROactive study (NCT00174993).

Intervention type: OTHER
Intervention: No Intervention
Description: Participants who previously received pioglitazone-matching placebo in the PROactive study (NCT00174993).
Study: NCT02029534

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin 20 mg

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin 80 mg
Study: NCT03886558

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A multicomponent intervention program was developed consisting of two 60-minute sessions per week, held on non-consecutive days, for a period of 8 months.
Description: The sessions consisted of a warm-up phase (10') in which individuals performed joint mobility exercises and walked at a rate of 3 km/h. Afterwards, muscular strength work was carried out on the upper and lower limbs, including calisthenic exercises, and the use of dumbbells or medicine balls (1-3kg). Generally, the exercises were organized in two sets of 10-15 repetitions, resting for two minutes between sets. Communal ball games and relay games were then practiced (over a distance of 30 meters). Finally, 10 minutes were devoted to relaxation and stretching exercises. multicomponent intervention program was designed and monitored by a specialist in gerontogymnastics.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A multicomponent intervention program was developed consisting of two 60-minute sessions per week, held on non-consecutive days, for a period of 8 months.
Description: The sessions consisted of a warm-up phase (10') in which individuals performed joint mobility exercises and walked at a rate of 3 km/h. Afterwards, muscular strength work was carried out on the upper and lower limbs, including calisthenic exercises, and the use of dumbbells or medicine balls (1-3kg). Generally, the exercises were organized in two sets of 10-15 repetitions, resting for two minutes between sets. Communal ball games and relay games were then practiced (over a distance of 30 meters). Finally, 10 minutes were devoted to relaxation and stretching exercises. multicomponent intervention program was designed and monitored by a specialist in gerontogymnastics.
Study: NCT01955057

Intervention type: BEHAVIORAL
Intervention: Research interviews

Intervention type: BEHAVIORAL
Intervention: Tests (Fagerström, Q-MAT, H.A.D.S, SCL 90-R)

Intervention type: BEHAVIORAL
Intervention: Projective methods (Thematic apperception Test, Rorschach)

Intervention type: BEHAVIORAL
Intervention: Carbon monoxide test
Study: NCT02194868

Intervention type: BIOLOGICAL
Intervention: Recipients
Description: 1. Adult recipient:~   * collected 20 ml pre-transplant~  * collected 30 ml for adults on day 20 post-transplant at engraftment for cell phenotype,~  * collected 30 ml on days 30, 60, 90, 180, 360 days post-HSCT for cell phenotyping at all time points, functional INKT at day 60 or 90 depending on the number of cells collected and anti-viral ELISPOT studies on days 180 and 360~2. Children recipients~   * collected residual blood pre-transplant~  * collected residual blood on day 20 post-transplant at engraftment for cell phenotype,~  * collected residual blood on days 20, 30, 90, 180 and 360 post-HSCT

Intervention type: BIOLOGICAL
Intervention: Donors
Description: 1. Adult donors :~   * collected 20 ml of blood, (if possible before granulocyte colony-stimulating factor (GCSF) administration)~  * collected 1 ml of the stem cell graft for adult recipient or 2 ml of bone marrow for children recipients These samples will be collected at the same time of those needed for transplant.~2. Children donors samples~   * collected residual blood~  * 2ml of bone marrow (bottom of tube)
Study: NCT00543764

Intervention type: OTHER
Intervention: pathway
Description: Comparison of pre and post pathway
Study: NCT02692677

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-42756493
Description: Participants will receive a single oral solution at a dose of 12 milligram (mg) of unlabeled JNJ--42756493 admixed with 14C- labeled JNJ--42756493.
Study: NCT05300295

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mentoring Program
Description: The Autism Mentorship Program is a psychosocial intervention that pairs adults and adolescents with autism spectrum disorder (ASD) in one-to-one mentoring relationships. AMP involves weekly meetings in an afterschool setting and targets the socio-emotional health and social connectedness of adolescents and adults with ASD.
Study: NCT02330796

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bucillamine
Description: Bucillamine Tablets
Study: NCT01786915

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Study: NCT04109573

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: high resolution anal manometry
Description: functional studies before and after anal laser ablation
Study: NCT01791166

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood test for detecting the circulatory anti-HLA antibodies by ELISA and LUMINEX tests
Study: NCT05103462

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telehealth Physical Therapy
Description: Weekly sessions of physical therapy provided using two-way, interactive, video technology consisting of education, advice and exercise instruction.
Study: NCT03142282

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: maintenance chemotherapy
Description: National Comprehensive Cancer Network (NCCN) or European Society for Medical Oncology (ESMO) suggested maintenance chemotherapy regimens: xeloda, bevacizumab

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Consolidative Radiotherapy
Description: Stereotacticbodyradiationtherapy (SBRT) or intensity modulated radiation therapy (IMRT) for metastatic sites (less than 5)
Study: NCT01136317

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole
Study: NCT02330796

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colchicine
Study: NCT02630784

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non-Invasive Ventilation with Homecare ventilator

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-Invasive Ventilation with ICU ventilator
Study: NCT02239809

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Stimulation of the trigeminal nerve (active stimulation)
Description: Participants will be randomized to active vs. sham stimulation during a period of 24 weeks with a one-way cross over at 12 weeks.~After 12 weeks, the participants receiving active electrical stimulation will continue under active stimulation until completion of the study.~Participants randomized to sham stimulation will be shifted to active stimulation and will be followed-up until completion of the study.~The study will be unblinded after 6 months of randomized stimulation. The second part of the study will be an open label prospective trial for evaluate long-term follow-up. The duration of the open label trial will be more 24 weeks.

Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo stimulation of the trigeminal nerve (placebo)
Description: Participants will be randomized to active vs. sham stimulation during a period of 24 weeks with a one-way cross over at 12 weeks. Patients of the placebo group will be implanted with a lead in the V1 branch of the trigeminal nerve, but will not receive stimulation.~After 12 weeks, the participants receiving active electrical stimulation will continue under active stimulation until completion of the study.~Participants randomized to placebo stimulation will be shifted to active stimulation and will be followed-up until completion of the study.~The study will be unblinded after 6 months of randomized stimulation. The second part of the study will be an open label prospective trial for evaluate long-term follow-up. The duration of the open label trial will be more 24 weeks.
Study: NCT03258827

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exercise with a towel
Description: Exercise program composes with warm-up, strengthening exercise, cold-down, 60 minutes/time, 3 times/week. A towel is an important tool for exercise. Total duration of the program is 3 months.
Study: NCT01786915

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study: NCT04453137

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Adalimumab originator
Description: Subcutaneous injection every other week

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Adalimumab originator
Description: Subcutaneous injection every other week

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adalimumab originator
Description: Subcutaneous injection every other week

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adalimumab biosimilar
Description: Subcutaneous injection every other week

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adalimumab biosimilar
Description: Subcutaneous injection every other week
Study: NCT00959634

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABT-126
Description: Dose administered twice daily on Study Days 1-10
Study: NCT01136317

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rabeprazole

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lactose
Study: NCT04058665

Intervention type: DEVICE
Intervention: Floseal
Description: Hemostatic agent
Study: NCT03292770

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Flushing Catheter
Description: A catheter will be used to performed a flushing of the cervical canal with culture media.
Study: NCT03364699

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: dietary supplementation
Description: The volunteers ingested 3 g daily of Soybean lecithin or fish oil rich in docosa-hexanoic acid (DHA) containing 1.5 g DHA and 0.3 g EPA (DHA:EPA = 5:1) or fish oil rich in eicosapentaenoic acid (EPA) containing 1.6 g EPA and 0.3 g DHA (EPA:DHA = 5.4:1) during 60 days.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: dietary supplementation
Description: The volunteers ingested 3 g daily of Soybean lecithin or fish oil rich in docosa-hexanoic acid (DHA) containing 1.5 g DHA and 0.3 g EPA (DHA:EPA = 5:1) or fish oil rich in eicosapentaenoic acid (EPA) containing 1.6 g EPA and 0.3 g DHA (EPA:DHA = 5.4:1) during 60 days.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: All volunteers performed two half-marathons. In the first half-marathon, all participants were not supplemented. In the second half-marathon, all participants were supplemented. Blood samples were collected before and after both half-marathon race.
Study: NCT04899531

Intervention type: OTHER
Intervention: Longitudinal observation
Description: No specific intervention, longitudinal (pre-post measurements) only
Study: NCT03698058

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Toddler milk
Description: Commercially available toddler milk

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Toddler milk
Description: Commercially available toddler milk
Study: NCT05298527

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Back Massage
Description: The woman lies face down and a pillow is placed under her forehead. Massage begins with effleurage. Petrissage is started from the sacrum and the hands are lifted up to the nape and repeated 4 times. After the petrissage movement is completed, effusion is applied to the area once. Friction is applied. After rubbing, tapotement is applied to the entire back.
Study: NCT02876211

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paricalcitol
Description: Paricalcitol 2 capsules/three times per week

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epoetin beta
Description: epoetin 1-3 times per week

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Epoetin beta
Description: epoetin 1-3 times per week

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 2 capsules/three times per week
Study: NCT00712608

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Infant formula
Description: Marketed cow's milk base infant formula 20 kcal/oz

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Infant formula
Description: cow's milk based infant formula with prebiotics, different level of fatty acids and fat and a different calcium source

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cow's milk infant formula
Description: Cow's milk based formula with prebiotics, different level of fatty acids and fat and a different calcium source
Study: NCT04620356

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DryNites Pyjama Pants
Description: DryNites Pyjama Pants are disposable, absorbent youth pants designed to help children manage bed wetting by absorbing involuntary urine loss and protecting the child's garments and bedding. DryNites Pyjama Pants are underwear-like alternatives that can be discreetly worn beneath pyjamas or nightwear during the bedwetting phase.
Study: NCT01939236

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: traditional Chinese medicine
Description: 1 bag of drug 2 times per day for 28 days according to syndrome differentiation. For example, the syndrome of one patient is qi deficiency and blood stasis, he will take drugs of qi deficiency and blood stasis each bag 2 times per day for 28days.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (gummeline)
Description: Placebo of each syndrome differentiation has the same weight and smell as traditional Chinese medicine of corresponding syndrome differentiation.~1 bag of drug 2 times per day for 28 days according to syndrome differentiation.~For example, the syndrome of one patient is qi deficiency and blood stasis, he will take drugs of qi deficiency and blood stasis each bag 2 times per day for 28 days.
Study: NCT02358720

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Arm A
Description: 1x24Gy high dose IMRT on spinal bone metastasis

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Arm B
Description: fractionated conformal RT 10 x 3 Gy on spinal bone metastasis
Study: NCT02138227

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Assisted CEaD Condition
Description: In the assisted condition, participants use the CEaD training materials supplemented with simulators to practice the communication skills. OPO requesters will be assisted by having the CEaD DVD supplemented through working the scenarios with live simulated patients who will be trained to act out the scenarios with the OPO requesters and provide feedback.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Autonomous CEaD Condition
Description: In the autonomous condition, participants view the CEaD training materials on a DVD along with a self-training guide.
Study: NCT02551900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Warm water exercise
Description: Warm water based cycling exercise training program will be based on cycling in warm water (temperature 34◦C ). Warm water exercise will be conducted at moderate intensity (60-70% maximum heart rate). The three groups were exercise 15 minutes on the first month, second month will be increased to 20 minutes and the last month will be increased to 30 minutes. The training program will be performed 3 times per week for 12 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Warm water exercise
Description: Warm water based cycling exercise training program will be based on cycling in warm water (temperature 34◦C ). Warm water exercise will be conducted at moderate intensity (60-70% maximum heart rate). The three groups were exercise 15 minutes on the first month, second month will be increased to 20 minutes and the last month will be increased to 30 minutes. The training program will be performed 3 times per week for 12 weeks.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold water exercise
Description: Cold water based cycling exercise training will be based on cycling in cold water (temperature 20◦C ). Cold water exercise will be conducted at moderate intensity (60-70% maximum heart rate). The three groups were exercise 15 minutes on the first month, second month will be increased to 20 minutes and the last month will be increased to 30 minutes. The training program will be performed 3 times per week for 12 weeks.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Land based cycling exercise
Description: Land based cycling exercise training will be based on ride a bicycle ergometer (Monark 894e, Sweden). Land based cycling exercise training will be conducted at moderate intensity (60-70% maximum heart rate). The three groups were exercise 15 minutes on the first month, second month will be increased to 20 minutes and the last month will be increased to 30 minutes. The training program will be performed 3 times per week for 12 weeks.