Study: NCT04513717

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apalutamide
Description: Nonsteroidal Antiandrogen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bicalutamide
Description: Antiandrogen

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bicalutamide
Description: Antiandrogen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bicalutamide
Description: Antiandrogen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Buserelin
Description: Luteinizing hormone-releasing hormone (LHRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buserelin
Description: Luteinizing hormone-releasing hormone (LHRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Buserelin
Description: Luteinizing hormone-releasing hormone (LHRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buserelin
Description: Luteinizing hormone-releasing hormone (LHRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Degarelix
Description: Gonadotropin-releasing hormone (GnRH) antagonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Degarelix
Description: Gonadotropin-releasing hormone (GnRH) antagonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Degarelix
Description: Gonadotropin-releasing hormone (GnRH) antagonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Degarelix
Description: Gonadotropin-releasing hormone (GnRH) antagonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Flutamide
Description: Antiandrogen

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Flutamide
Description: Antiandrogen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Flutamide
Description: Antiandrogen

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Goserelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Goserelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Histrelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Histrelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Histrelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Histrelin
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leuprolide
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leuprolide
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leuprolide
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leuprolide
Description: Gonadotropin-releasing hormone (GnRH) agonist

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies