TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04496921

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin K supplementation, dose #1
Description: Vitamin K supplement : 2mg, once a day, for 6 months. Complete biochemical profile, weight and size (body mass index), drugs list, pulmonary function by spirometry (FEV, etc.). Food frequency questionnaire.

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin K supplementation, dose #2
Description: Vitamin K supplement : 7mg, twice a week, for 6 months. Complete biochemical profile, weight and size (body mass index), drugs list, pulmonary function by spirometry (FEV, etc.). Food frequency questionnaire.
Study: NCT02755675

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 68Ga-NOTA-AE105 PET/CT
Description: Following injection of 68Ga-NOTA-AE105 the patients will be subjected to PET/CT
Study: NCT01049919

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bone marrow concentration device
Description: Concentration of autologous bone marrow aspirate for intramuscular delivery to affected limb

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Placebo procedure (sham)
Description: Sham bone marrow aspiration, sham delivery to affected limb
Study: NCT01751464

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WrapAround Case Management
Description: Youth Injured by Violence will be paired with a support worker who has extensive experience working with youth affected by violence.It is important to note that the wraparound concept involves individualized care planning and management. As such, the specific care plan will be different for each participant. Through early intensive meetings, they will develop a mentoring relationship. They will work with the youth to develop a support team, which may include family, teachers, child welfare workers and truly anyone the youth has decided can help them in their path to making positive choices.
Study: NCT02634294

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peg interferon alfa-2b
Description: Eligible patients were treated with pegylated interferon alpha-2b (Peg Intron®; Schering-Plough (Brinny) Company, Innishannon, County Cork, Ireland) 1\~1.5ug/kg qw, until occurrence of grade II or higher grade of acute graft versus host disease, or no response to treatment after 8 doses of treatments.
Study: NCT00901329

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NexGen Gender Fixed Bearing Knee prosthesis
Description: new female prosthesis

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NexGen LPS-Flex Fixed Bearing Knee prosthesis
Description: standard knee prosthesis
Study: NCT05521893

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telemedicine care
Description: In the telemedicine group, the appointments are performed online via scheduled videoconferences, on a monthly basis.~All women in the telemedicine group receive a smartphone with the installed application that enable transfer of the measured capillary glucose concentration.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care
Description: In the standard care group, visits are scheduled at the diabetes clinic on a monthly basis.
Study: NCT01276327

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linagliptin + Pioglitazone
Description: Medium doses, oral administration
Study: NCT02811965

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Offloading Device B
Description: Heel offloading device that utilizes pressure absorbing filling to offload the heel. Device has a published clinical study demonstrating effectiveness at reducing heel ulceration rate

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Offloading Device C
Description: Heel offloading device that utilizes a similar pressure absorbing filling to Offloading Device B; however this device does not have published clinical literature demonstrating effectiveness at reducing heel ulceration in the clinic.
Study: NCT04181697

Intervention type: DEVICE
Intervention: PA measurement with Fitbit Charge 3
Description: Measurement of PA with Fitbit for all participants and controls.

Intervention type: DEVICE
Intervention: PA measurement with Fitbit Charge 3
Description: Measurement of PA with Fitbit for all participants and controls.

Intervention type: DEVICE
Intervention: PA measurement with Fitbit and ActiGraph GT3X
Description: Measurement of PA with ActiGraph for a subgroup of 20 participants.
Study: NCT00944125

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dual Site LV Pacing
Description: Dual Site LV Pacing vs. BiV Pacing for a total of six months which includes two three crossover periods.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dual Site LV Pacing
Description: Dual Site LV Pacing vs. BiV Pacing for a total of six months which includes two three crossover periods.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BiV Pacing
Description: Dual Site LV Pacing vs. BiV Pacing for a total of six months which includes two three crossover periods.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BiV Pacing
Description: Dual Site LV Pacing vs. BiV Pacing for a total of six months which includes two three crossover periods.
Study: NCT03285152

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic Diet (KD)
Description: specially-formulated very low carbohydrate meals (KD)

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Diet (SD)
Description: counseling on maintaining adequate nutritional intake from a normal diet (SD)
Study: NCT02700217

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bupivacaine and Diamorphine

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Remifentanil, Propofol and Cistracurium

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Remifentanil, Propofol and Cistracurium

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine and Rectus Sheath injection
Study: NCT02548156

Intervention type: OTHER
Group type: OTHER
Intervention: Test Dentifrice
Description: Marketed dentifrice containing 1150ppm fluoride and 5% w/w KNO3

Intervention type: OTHER
Group type: OTHER
Intervention: Reference Dentifrice
Description: Marketed dentifrice containing 1150ppm fluoride and 5% w/w KNO3

Intervention type: OTHER
Group type: OTHER
Intervention: Comparator Dentifrice
Description: Marketed dentifrice containing 1150ppm fluoride and 5% w/w KNO3

Intervention type: OTHER
Group type: OTHER
Intervention: Orange Juice
Description: Teeth will be rinsed with orange juice followed by rinsing with de-ionised water in test dentifrice and comparator dentifrice arms.

Intervention type: OTHER
Group type: OTHER
Intervention: Orange Juice
Description: Teeth will be rinsed with orange juice followed by rinsing with de-ionised water in test dentifrice and comparator dentifrice arms.

Intervention type: OTHER
Group type: OTHER
Intervention: De-ionised water
Description: Teeth will be rinsed with de-ionised water followed by reference dentifrice and followed by rinsing with orange juice in test dentifrice and comparator dentifrice arms.

Intervention type: OTHER
Group type: OTHER
Intervention: De-ionised water
Description: Teeth will be rinsed with de-ionised water followed by reference dentifrice and followed by rinsing with orange juice in test dentifrice and comparator dentifrice arms.

Intervention type: OTHER
Group type: OTHER
Intervention: De-ionised water
Description: Teeth will be rinsed with de-ionised water followed by reference dentifrice and followed by rinsing with orange juice in test dentifrice and comparator dentifrice arms.
Study: NCT03243110

Intervention type: DIAGNOSTIC_TEST
Intervention: breathing test
Description: Spirometry is a non-invasive means of measuring lung function: The participant is asked to take a deep breath and then exhale into the sensor as hard and as long as possible. Soft nose clips may be used to prevent air escaping through the nose. If the participant does not show a definitive diagnosis of asthma, a methacholine challenge test will be performed to elicit bronchoconstriction in participants. In methacholine challenge test, the participant breaths in standardized dose of nebulized methacholine again. Methacholine challenge test is widely accepted and standardized method for assisting the diagnosis of asthma and there will be no experimental altercation in the method methacholine challenge is performed.
Study: NCT03871543

Intervention type: DEVICE
Group type: OTHER
Intervention: AquaComfort Plus
Description: Test Lens 1

Intervention type: DEVICE
Group type: OTHER
Intervention: Acuvue Oasys 1-Day
Description: Test Lens 2
Study: NCT02671838

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Musculoskeletal ultrasound program
Description: Using a musculoskeletal ultrasound program to help improve medication adherence
Study: NCT02743325

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SVT ablation by ALARA protocol
Description: Catheter ablation is a procedure that uses radiofrequency energy (similar to microwave heat) to destroy a small area of heart tissue that is causing arrhythmias. Destroying this tissue helps restore your heart's regular rhythm. The usage of CartoUnivuTM allows a seamless combination of a fluoro image and Carto® 3 System maps into a single view.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: SVT ablation by conventional protocol
Description: Catheter ablation is a procedure that uses radiofrequency energy (similar to microwave heat) to destroy a small area of heart tissue that is causing arrhythmias. Destroying this tissue helps restore your heart's regular rhythm. The convention Ablation procedure works without a 3D navigation System.
Study: NCT02767167

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Semi-skimmed cow's milk
Description: 430ml of semi-skimmed cow's milk / day for 12 weeks
Study: NCT02172443

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tiotropium inhalation powder capsules

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atrovent

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: placebo to Atrovent

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo to tiotropium inhalation capsules
Study: NCT02976129

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: V565
Description: Daily dosing of V565 three times a day orally for 6 weeks
Study: NCT01600612

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: carbetocin
Description: 10 ug of carbetocin will be given intravenously to patients with atonic postpartum hemorrhage

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: misopristol
Description: 600 ug of misopristol will be given sublingually to patients with atonic postpartum hemorrhage

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: oxytocin
Description: 30 IU of oxytocin will be given intravenously to patients with atonic postpartum hemorrhage
Study: NCT01510587

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 4-Health Educational curriculum
Description: During the intervention, parents meet about every 3 weeks (90 min/session) in small groups with facilitators. During meetings classroom activities aim to integrate 3 areas: 1) parents' knowledge about healthy diets, physical activity and improved body image; 2) parents' understanding, skills and potential roles as positive change-agents (i.e., parenting and behavior management); and 3) parents' learning and practicing cognitive-behavioral exercises that encourage specific skills within the family/home setting. Between monthly meetings, participants explore a suggested online websites or facilitator-assigned questions and provide feedback. The majority of outside time/assignments for parents is spent doing take-home activities with their preteen child and family.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Living Information
Description: During the Healthy Living Information intervention, participants receive packets delivered to their homes by mail at intervals similar to the meeting intervals for the educational curriculum intervention. (10 total packets.) Approximately every three weeks between late September 2011 and April 2012, corresponding approximately to the meeting times for the 4-Health Educational Program, participants in the Healthy Living Information control group receive mailed packets of information.
Study: NCT02159534

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Primebrain
Description: Primebrain stimulation programme aims to facilitate the infant's self-organization of postural competences by proposing varied sensorimotor experiences in a context supporting parent-child interaction.

Intervention type: OTHER
Group type: OTHER
Intervention: Primebrain
Description: Primebrain stimulation programme aims to facilitate the infant's self-organization of postural competences by proposing varied sensorimotor experiences in a context supporting parent-child interaction.
Study: NCT01276327

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linagliptin/Pioglitazone
Description: Medium dose oral administration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linagliptin/Pioglitazone
Description: Medium dose oral administration
Study: NCT03533400

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Jamboxx Respiratory Therapy Device
Description: Jamboxx Respiratory Therapy Device is a novel device that uses interactive gaming to encourage patient compliance with their prescribed respiratory therapy routines. The device consists of a computer game controller with mouthpiece containing a breath flow sensor that connects to a tablet. With the Jamboxx respiratory therapy device, users can choose from a suite of breath controlled respiratory therapy games to guide them through their routines while receiving real-time feedback, and long-term progress tracking.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Jamboxx Musical Device
Description: Jamboxx musical device is a hands free, breath controlled music device designed for people with quadriplegia. It resembles a common harmonica in that the user slides a mouthpiece along its horizontal axis to change the pitch of the instrument. The device connects to a personal computer via a mini USB to USB cable to interface with software that provides visual feedback for playing notes and sends the information to the computer speakers. The mouthpiece acts as a transducer, changing air pressure created by the user's lungs to a joystick signal to the computer via a differential pressure sensor. The Jamboxx musical device can produce musical sounds of many instruments (trumpet, drums, etc.) in many different scales and in any key

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Jamboxx Musical Device
Description: Jamboxx musical device is a hands free, breath controlled music device designed for people with quadriplegia. It resembles a common harmonica in that the user slides a mouthpiece along its horizontal axis to change the pitch of the instrument. The device connects to a personal computer via a mini USB to USB cable to interface with software that provides visual feedback for playing notes and sends the information to the computer speakers. The mouthpiece acts as a transducer, changing air pressure created by the user's lungs to a joystick signal to the computer via a differential pressure sensor. The Jamboxx musical device can produce musical sounds of many instruments (trumpet, drums, etc.) in many different scales and in any key
Study: NCT03861468

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care pathway
Description: Screening for OSA using a combination of bicarbonate assay and STOP-BANG questionnaire and further management by a pneumologist as necessary
Study: NCT01423513

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fibular Taping
Description: Tape with be applied with tension.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Taping
Description: Tape will be applied without tension
Study: NCT01570075

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: HR
Description: SR was carried out under general anesthesia using a right subcostal incision with a midline extension. Intra-operative ultrasonography was performed routinely to evaluate the tumor burden, liver remnant, and the possibility of a negative resection margin. Anatomic resection, in the form of segmentectomy and/or subsegmentectomy as described by Makuuchi et al. (16) was the preferred surgical method of liver resection. Pringle's maneuver was routinely used with a clamp and unclamp time of 10 min and 5 min, respectively; this technique was used repeatedly throughout the entire procedure.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: RFA
Description: For PRFA, we used a commercially available system with a 375-KHz computer-assisted radiofrequency generator (Elektrotom HiTT 106, Berchtold, Medizinelektronik, Germany) and an open-perfused electrode (Berchtold, Tuttlingen, Germany) of 15 cm (or 20 cm), 14 Ga, and a 15 mm (or 20 mm) active electrode tip with microbores.
Study: NCT02713217

Intervention type: OTHER
Intervention: Usual Care
Description: This condition is defined as usual care occurring within Community Based Outpatient Clinics (CBOCs), which typically does not involve substantial integration of mental health care and primary care.

Intervention type: OTHER
Intervention: Blended Telemedicine-Based Integrated Care
Description: This condition involves exposure to a blended collaborative care model that includes care management for depression and alcohol disorders and virtual co-location of doctoral-level mental health providers with prompt access through tele-video or telephone communication.
Study: NCT04007393

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Lifestyle Modification Therapy (LSMT)
Description: LSMT will consist of both in-person and by telephone sessions delivered throughout the entirety of the 48-week intervention phase. Each session will last 30-60 minutes. A trained study coordinator (a registered dietician or someone trained by our registered dietician) will delivery this therapy which consists of counseling using education, goal setting and barrier reduction. Topics covered will include calories, tracking, healthy food choices, reducing high fat, added sugar foods, setting goals and portions, changing the quality of your diet, volumetrics, purposeful activity, quick and easy meals, problem solving, food cues and eating patterns, emotional eating, accurate tracking, eating away from home, unhelpful thoughts, structured menus and the role of protein, social cues, managing stress, slips and relapse prevention, long-term physical activity and overcoming obstacles, high-risk situation and keys to success, motivation and looking to the future (long-term plans).

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Lifestyle Modification Therapy (LSMT)
Description: LSMT will consist of both in-person and by telephone sessions delivered throughout the entirety of the 48-week intervention phase. Each session will last 30-60 minutes. A trained study coordinator (a registered dietician or someone trained by our registered dietician) will delivery this therapy which consists of counseling using education, goal setting and barrier reduction. Topics covered will include calories, tracking, healthy food choices, reducing high fat, added sugar foods, setting goals and portions, changing the quality of your diet, volumetrics, purposeful activity, quick and easy meals, problem solving, food cues and eating patterns, emotional eating, accurate tracking, eating away from home, unhelpful thoughts, structured menus and the role of protein, social cues, managing stress, slips and relapse prevention, long-term physical activity and overcoming obstacles, high-risk situation and keys to success, motivation and looking to the future (long-term plans).

Intervention type: DRUG
Group type: OTHER
Intervention: Phentermine Pill
Description: Phentermine will be started only if a participant does not lose 5% of BMI after 12 or 24 weeks of LSMT depending on their random assignment. Subjects will take 15 mg of phentermine every morning for 12 weeks at which time there will be an assessment of weight loss. Subjects who achieve 5% or more BMI reduction after 12 weeks of phentermine will continue 15 mg every morning for the remainder of the study (through week 48) along with their LSMT.
Study: NCT03009071

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Doin (conduction exercise)
Description: Doin (conduction exercise) will be combined with acupuncture as active and passive movement to the aim of effective treatment of pain and functional disability. Doin (conduction exercise) sessions will be conducted 2 times a week for 5 weeks.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture
Description: Acupuncture will be performed with manual stimulation (needle twirling) to evoke de-qi sensation. Acupuncture sessions will be conducted 2 times a week for 5 weeks.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture will be performed with manual stimulation (needle twirling) to evoke de-qi sensation. Acupuncture sessions will be conducted 2 times a week for 5 weeks.
Study: NCT02640794

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clopidogrel
Description: Clopidogrel therapy will start within 24 hrs before the TAVI procedure in cases where a transfemoral approach is used and within 24 hrs after the TAVI procedure in cases where a transapical approach is used. The initial dose of clopidogrel will be of 300 mg followed by 75 mg/die. The duration of clopidogrel treatment will be of 3 months.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin
Description: Aspirin/acetylsalicylic acid (80-325 mg/d). Aspirin/acetylsalicylic acid therapy will start at least 24 hrs before the TAVI procedure and continued for at least 6 months.
Study: NCT04007393

Intervention type: DRUG
Group type: OTHER
Intervention: Phentermine Pill
Description: Phentermine will be started only if a participant does not lose 5% of BMI after 12 or 24 weeks of LSMT depending on their random assignment. Subjects will take 15 mg of phentermine every morning for 12 weeks at which time there will be an assessment of weight loss. Subjects who achieve 5% or more BMI reduction after 12 weeks of phentermine will continue 15 mg every morning for the remainder of the study (through week 48) along with their LSMT.

Intervention type: DRUG
Group type: OTHER
Intervention: Topiramate Pill
Description: Participants who do no not achieve at least 5% BMI reduction after 12 weeks of phentermine+LSMT will be re-randomized 1:1 to either topiramate+phentermine+LSMT or topiramate+placebo+LSMT. Topiramate dosing will begin at 50 mg every morning for the first 7 days, and then increase to 100 mg every morning through week 48. At the end of week 48 the taper off will be 50 mg every morning for 7 days and then discontinue.

Intervention type: DRUG
Group type: OTHER
Intervention: Topiramate Pill
Description: Participants who do no not achieve at least 5% BMI reduction after 12 weeks of phentermine+LSMT will be re-randomized 1:1 to either topiramate+phentermine+LSMT or topiramate+placebo+LSMT. Topiramate dosing will begin at 50 mg every morning for the first 7 days, and then increase to 100 mg every morning through week 48. At the end of week 48 the taper off will be 50 mg every morning for 7 days and then discontinue.