Study: NCT03699644

Intervention type: DEVICE
Intervention: Spectral-Domain Optical Coherence Tomography (SD-OCT)
Description: Each participant in this study will undergo Optical coherence tomography (OCT), a non-invasive imaging test of the eye, one time. OCT uses light waves to take cross-section pictures of the retina, which are generated using scattered light waves.

Intervention type: DEVICE
Intervention: Spectral-Domain Optical Coherence Tomography (SD-OCT)
Description: Each participant in this study will undergo Optical coherence tomography (OCT), a non-invasive imaging test of the eye, one time. OCT uses light waves to take cross-section pictures of the retina, which are generated using scattered light waves.

Intervention type: DEVICE
Intervention: Spectral-Domain Optical Coherence Tomography (SD-OCT)
Description: Each participant in this study will undergo Optical coherence tomography (OCT), a non-invasive imaging test of the eye, one time. OCT uses light waves to take cross-section pictures of the retina, which are generated using scattered light waves.

Intervention type: DEVICE
Intervention: Magnetic Resonance Imaging (MRI)
Description: Each participant in this study will undergo a single Magnetic resonance imaging (MRI) scan, a scanning technique for creating detailed images of the human body. The scan uses a magnetic field and radio waves to generate images of the brain.

Intervention type: DEVICE
Intervention: Magnetic Resonance Imaging (MRI)
Description: Each participant in this study will undergo a single Magnetic resonance imaging (MRI) scan, a scanning technique for creating detailed images of the human body. The scan uses a magnetic field and radio waves to generate images of the brain.

Intervention type: DEVICE
Intervention: Magnetic Resonance Imaging (MRI)
Description: Each participant in this study will undergo a single Magnetic resonance imaging (MRI) scan, a scanning technique for creating detailed images of the human body. The scan uses a magnetic field and radio waves to generate images of the brain.

Intervention type: DEVICE
Intervention: Positron Emission Tomography (PET)
Description: Each participant in this study will undergo a single Positron emission tomography (PET) scan of the brain. PET is a nuclear medicine functional imaging technique that is used to observe metabolic processes in the brain as an aid to the diagnosis of disease using the combination of a radioactive tracer, camera, and a computer.

Intervention type: DEVICE
Intervention: Positron Emission Tomography (PET)
Description: Each participant in this study will undergo a single Positron emission tomography (PET) scan of the brain. PET is a nuclear medicine functional imaging technique that is used to observe metabolic processes in the brain as an aid to the diagnosis of disease using the combination of a radioactive tracer, camera, and a computer.

Intervention type: DEVICE
Intervention: Positron Emission Tomography (PET)
Description: Each participant in this study will undergo a single Positron emission tomography (PET) scan of the brain. PET is a nuclear medicine functional imaging technique that is used to observe metabolic processes in the brain as an aid to the diagnosis of disease using the combination of a radioactive tracer, camera, and a computer.

Intervention type: DIAGNOSTIC_TEST
Intervention: Comprehensive Ophthalmic Examination
Description: Each participant in this study will receive one comprehensive eye examination which will be performed by a licensed ophthalmologist at the University of Michigan. This examination will include the assessment of the participant's visual acuity, a slit lamp examination which will look at the anterior and posterior tissues of the eye including the retina using various lights and lenses, and intraocular pressures.

Intervention type: DIAGNOSTIC_TEST
Intervention: Comprehensive Ophthalmic Examination
Description: Each participant in this study will receive one comprehensive eye examination which will be performed by a licensed ophthalmologist at the University of Michigan. This examination will include the assessment of the participant's visual acuity, a slit lamp examination which will look at the anterior and posterior tissues of the eye including the retina using various lights and lenses, and intraocular pressures.

Intervention type: DIAGNOSTIC_TEST
Intervention: Comprehensive Ophthalmic Examination
Description: Each participant in this study will receive one comprehensive eye examination which will be performed by a licensed ophthalmologist at the University of Michigan. This examination will include the assessment of the participant's visual acuity, a slit lamp examination which will look at the anterior and posterior tissues of the eye including the retina using various lights and lenses, and intraocular pressures.

Intervention type: DEVICE
Intervention: Fundus Photography
Description: Each participant in this study will undergo fundus photography of each eye. Fundus photography involves the use of a retinal camera coupled with a low power microscope to capture photographs of the retina.

Intervention type: DEVICE
Intervention: Fundus Photography
Description: Each participant in this study will undergo fundus photography of each eye. Fundus photography involves the use of a retinal camera coupled with a low power microscope to capture photographs of the retina.

Intervention type: DEVICE
Intervention: Fundus Photography
Description: Each participant in this study will undergo fundus photography of each eye. Fundus photography involves the use of a retinal camera coupled with a low power microscope to capture photographs of the retina.