TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04566510

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard))
Description: Next-generation bed net combining insecticides with different modes of action

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0))
Description: Next-generation bed net combining an insecticide with a synergist

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Social behaviour change communication
Description: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social behaviour change communication
Description: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
Study: NCT02769416

Intervention type: OTHER
Intervention: Data and sample repository
Description: Subjects with spinal cord and/or traumatic brain injury, family members and healthy volunteers will provide data and samples.

Intervention type: OTHER
Intervention: Data and sample repository
Description: Subjects with spinal cord and/or traumatic brain injury, family members and healthy volunteers will provide data and samples.
Study: NCT03279250

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apalutamide
Description: Given PO

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Gonadotropin-releasing Hormone Analog
Description: Given IM
Study: NCT03984448

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT scan

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT scan

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin Hydrochloride
Description: Given IV

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Etoposide
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Given IV
Study: NCT05882162

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Coronectomy
Description: Removal of crown part of the mandibular third molar

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coronectomy
Description: Removal of crown part of the mandibular third molar

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulp Capping with calcium silicate
Description: Application of a pulp capping material (BiodentineTM, Septodont, St Maur-des-Fosses, France) on pulp tissue to preserve the vitality of the residual pulp and prevent inflammation
Study: NCT00375934

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: diclofenac potassium (XP21L)
Description: 25 mg capsule, every 6 hours

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral placebo capsule, every 6 hours
Study: NCT03442426

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated model of primary care
Description: Intervention includes: 1) consistent risk screening and assessment; 2) care coordination and system navigation; 3) patient/caregiver engagement and shared decision-making; and 4) enabling technology supports.
Study: NCT03640897

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Liniderm
Description: Cleaning of the diaper area with Liniderm at each diaper change during 28 days

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Wipes
Description: Cleaning of the diaper area with wipes at each diaper change during 28 days

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Water
Description: Cleaning of the diaper area with water and cotton pads at each diaper change during 28 days
Study: NCT04522427

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use Multifocal and Extended Depth-of-Focus Intraocular Lenses(IOLs)
Description: IOLs include AT LISA tri 839MP, AcrySof IQ PanOptix IOL, TECNIS Symfony EDOF

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Use Monofocal intraocular lenses(IOLs)
Description: Monofocal IOLs include 409(Zeiss), AcrySof, TECNIS IOLS
Study: NCT04052958

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: IMT - inspiratory muscle training
Description: respiratory strength or indurance training with respiratory therapy device

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: IMT - inspiratory muscle training
Description: respiratory strength or indurance training with respiratory therapy device
Study: NCT01019590

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Benicar HCT ® Tablets 40 mg/25 mg
Study: NCT01134887

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Informational Guide for Patients
Description: Veterans received a copy of the NIA guide for Talking with Your Doctor. This pamphlet was specifically developed for this purpose (updated in 2002). It has pictorials and is written at an 8th grade level.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Informational Guide for Patients
Description: Veterans received a copy of the NIA guide for Talking with Your Doctor. This pamphlet was specifically developed for this purpose (updated in 2002). It has pictorials and is written at an 8th grade level.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video-Assisted Coaching
Description: Physicians participated in an audiotaped intensive 30 minute, one-on-one educational intervention with PI Frankel after their first set of visits from their three participating patients, but before seeing them for follow-ups. The main goal of this video-assisted coaching session was to review and discuss the analysis of the physician's videotaped visits using the Four Habits framework, with a particular focus on improving communication about self-management.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Monograph for Physicians
Description: Primary care providers randomly assigned to the Intervention-Physicians arm of this study received a copy of the Four Habits of Highly Effective Physicians. The Four Habits provided practical evidence-based advice for improving patient-physician communication.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational Coaching
Description: an educator met with each Veteran in the intervention arm individually for 20-30 minutes to review the material in the pamphlet and develop a plan for enhancing communication about self-management of hypertension with their doctor \[Coaching\]. To facilitate communication change, the educator assisted the patient in setting a goal to achieve during their visit. The educator also provided telephone follow-up within 24 hours to review satisfaction and effectiveness of the visit and assess barriers and facilitators to communicating about self-management.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The primary care providers randomly assigned to the Control-Physicians arm did not receive any additional coaching or resources and conducted their practice as usual.
Study: NCT04634968

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Motivational Interviewing interaction
Description: Telephone peer counselling+ Brief Motivational Interviewing interaction, and telephone-based interview after receiving all information.

Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: General health communication
Description: Telephone peer counselling+ General health communication, and telephone-based interview, and telephone-based interview after receiving all information.
Study: NCT04295304

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Retinal surgery with implantation of epi-retinal device
Description: Retinal surgery and implantation of epi-retinal prosthesis
Study: NCT02392546

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: elobixibat

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: elobixibat

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: elobixibat

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Study: NCT01898546

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary angioplasty
Description: Primary angioplasty preceded by 300 mg aspirin plus 600 mg clopidogrel oral load doses. The radial approach and the use of thrombus aspiration catheters will be recommended. Stent will be implanted in all cases. Balloon pre-dilatation or direct stenting will be decided according to lesion characteristics.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Primary angioplasty
Description: Primary angioplasty preceded by 300 mg aspirin plus 600 mg clopidogrel oral load doses. The radial approach and the use of thrombus aspiration catheters will be recommended. Stent will be implanted in all cases. Balloon pre-dilatation or direct stenting will be decided according to lesion characteristics.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Postconditioning
Description: 1 min after stent deployment, the angioplasty balloon will be re-inflated 4 times during 1 min at low-pressure (4 to 6 atmospheres), each separated by 1 min of reflow.
Study: NCT00087204

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: becatecarin
Description: Given IV

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: laboratory biomarker analysis
Description: Correlative studies
Study: NCT01852344

Intervention type: DRUG
Group type: OTHER
Intervention: Methylphenidate
Description: 20 mgs of methylphenidate or placebo to be administered one hour before task performance

Intervention type: DRUG
Group type: OTHER
Intervention: Methylphenidate
Description: 20 mgs of methylphenidate or placebo to be administered one hour before task performance

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: 20 mgs of methylphenidate or a placebo to be administered one hour before task performance

Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: 20 mgs of methylphenidate or a placebo to be administered one hour before task performance

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Easy Behavioral Task
Description: Subjects do an easy version of the Letter E Task.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Easy Behavioral Task
Description: Subjects do an easy version of the Letter E Task.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Hard Behavioral Task
Description: Subjects do a hard version of the Letter E Task.

Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Hard Behavioral Task
Description: Subjects do a hard version of the Letter E Task.
Study: NCT00410280

Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: IMA-638 is a biologic
Study: NCT03482310

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Using the Neuroport cortical recording array to determine the desired grasp pattern for a functional electrical stimulation (FES) system
Description: Participants will be asked to think about holding different shaped objects, and the recorded cortical signal patterns will be decoded to match those grasp shapes
Study: NCT00790296

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thyrotropin releasing hormone (TRH)
Description: 0.5mg and 1.5mg

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline
Study: NCT02183298

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1356 BS - intravenous

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1356 BS - Tablet

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study: NCT02225067

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium (13C)Carbonate
Description: Visit 1 and Visit 2, 24-hour gastric pH monitoring and C13-CAC breath test containing 200 mg of Calcium (13C)Carbonate
Study: NCT02014532

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Montelukast
Description: Patients in Montelukast Group were treated with scaling and root planing (SRP) along with Montelukast (Montair 10mg), 1 tablet twice daily for 3 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients in Placebo Group were treated with scaling and root planing (SRP) along with Placebo therapy, 1 tablet twice daily for 3 weeks.
Study: NCT04561817

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ipatasertib
Description: 400mg PO daily: day 1-21 of 28 day cycle

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ipatasertib
Description: 400mg PO daily: day 1-21 of 28 day cycle

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: 80 mg/m2 IV weekly: day 1, 8, 15 of 28 day cycle

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: 80 mg/m2 IV weekly: day 1, 8, 15 of 28 day cycle
Study: NCT03550716

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: mTESE
Description: mTESE is performed according to the initial description by Schlegel (4). General anesthesia is used. Midline incision of the scrotum is made and carried down to the level of the tunica vaginalis, which is opened to deliver the testis. Equatorial incision is made and the testis bivalved. The operating microscope is used to identify plump-appearing seminiferous tubules, and biopsies are taken from these areas. These samples are examined by an embryologist in the operating room after initial gross dispersion by passing the tissue through a 24G angiocatheter. The procedure is stopped if spermatozoa are found. If no plump tubules are found, random biopsies targeting every area of the testis are taken. If necessary the procedure is carried out on the contralateral testis. Hemostasis is obtained with careful bipolar cautery, and the tunica albuginea and the tunica vaginalis are closed with a running 4-0 Vicryl. Standard scrotal closure is performed and gentle pressure dressing is applied.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TESA
Description: In general anesthesia an 18 gauge needle is introduced into each testis, and negative pressure applied with a 10 ml syringe. Multiple passes throughout the entire testis, numbering 50-100 passes, are made through a single percutaneous/tunical entry and continued until tissue is visible in the hub of the needle. This is removed by brisk extraction of the needle and pressure held to tamponade bleeding. The aspirated tissue is examined by an embryologist in the operating room after initial gross dispersion by passing the tissue through a 24 gauge angiocatheter.
Study: NCT01214616

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: afatinib 20mg
Description: patient to receive afatinib low dose po daily in combination with vinorelbine iv

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: afatinib 40mg
Description: patient to receive afatinib high dose po daily in combination with vinorelbine iv

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: vinorelbine IV 25 or 20mg/m2
Description: patient to receive standard dose vinorelbine once a week for four times per cycle
Study: NCT01116245

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ADXS11-001 (Lm-LLO-E7)
Description: ADXS11-001 at one of three dose levels given as 3 vaccinations separated by 4 weeks with an oral antibiotic regimen subsequent to dosing.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ADXS11-001 (Lm-LLO-E7)
Description: ADXS11-001 at one of three dose levels given as 3 vaccinations separated by 4 weeks with an oral antibiotic regimen subsequent to dosing.

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ADXS11-001 (Lm-LLO-E7)
Description: ADXS11-001 at one of three dose levels given as 3 vaccinations separated by 4 weeks with an oral antibiotic regimen subsequent to dosing.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control
Description: 3 intravenous infusions of normal saline at 28 day intervals. All infusions will be preceded by prophylactic NSAID and antihistamine, and followed 3d later with antibiotic.
Study: NCT02596347

Intervention type: PROCEDURE
Intervention: Blood draw
Description: We will draw 4 heparin tubes for peripheral blood mononuclear cells (PBMC)

Intervention type: PROCEDURE
Intervention: Blood draw
Description: We will draw 4 heparin tubes for peripheral blood mononuclear cells (PBMC)

Intervention type: PROCEDURE
Intervention: bronchoscopy
Description: CBD subjects will undergo a bronchoscopy with lavage. This is the passage of a think flexible tube through the nose into the windpipe then into the bronchial tubes. Sterile saltwater solution is through the flexible tube then immediately removed.
Study: NCT05775692

Intervention type: DRUG
Intervention: fluconazole
Description: According to the models of population pharmacokinetics,the investigators and want to correlate use of fluconazole with treatment effectiveness and safety in newborns
Study: NCT04533763

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Technology-based Mindful Living program
Description: The program is delivered using web-based group conferencing. During each session, participants are taught new stress management and coping techniques. Each week there is opportunity to apply techniques to real world situations for practice. Participants have a group orientation session, and then meet for 10 weeks. Group sessions last 1.5 - 2 hours. Booster sessions occur approximately 4.5 and 9 months post- randomization. Program includes training in mindfulness, cognitive behavioral stress management, relaxation, imagery, prioritizing meaningful activities, communication, and coping strategies. Content is geared toward concerns of cancer survivors.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Technology-based Healthy Lifestyles program
Description: The program is delivered using web-based group conferencing. Sessions include content from the National Cancer Institute, American Cancer Society, and health care providers with expertise in oncology. All content is geared to promoting healthy living among ovarian cancer survivors. Participants have a group orientation session, and then meet for 10 weeks, with group sessions lasting 1.5 - 2 hours. Booster sessions occur approximately 4.5 and 9 months post-randomization. Healthy Lifestyle sessions include topics such as nutrition, exercise, sleep, quality of life, survivorship, and cognitive function with content geared toward concerns of cancer survivors.
Study: NCT03984448

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lumbar Puncture
Description: Undergo lumbar puncture

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Positron Emission Tomography
Description: Undergo PET scan

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET scan

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisone
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Given PO

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: Given IV

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vincristine Sulfate
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine Sulfate
Description: Given IV
Study: NCT02844465

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Visualase MRI-Guided Laser Ablation
Description: All subjects will undergo MRI-guided laser ablation of the amygdala and hippocampus with the Visualase System.
Study: NCT01919554

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 500 IR house dust mites allergen extract tablet
Description: One sublingual tablet daily during 10 days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 1000 IR house dust mites allergen extract tablet
Description: Two sublingual tablets daily during 10 days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 1500 IR house dust mites allergen extract tablet
Description: Three sublingual tablets daily during 10 days

Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet
Description: One, two or three sublingual placebo tablets daily during 10 days matching with the sublingual immunotherapy tablets