Study: NCT03621696

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity modulated radiation therapy
Description: -IMRT or IMPT can be used

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity modulated proton therapy
Description: -IMRT or IMPT can be used

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity modulated proton therapy
Description: -IMRT or IMPT can be used

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Intensity modulated proton therapy
Description: -IMRT or IMPT can be used

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: -Standard of care

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: -Standard of care

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: -Standard of care

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FACT-H&N
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FACT-H&N
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FACT-H&N
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MD Anderson Dysphagia Inventory
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MD Anderson Dysphagia Inventory
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MD Anderson Dysphagia Inventory
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: University of Michigan Xerostomia Index
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: University of Michigan Xerostomia Index
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: University of Michigan Xerostomia Index
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scale of Subjective Total Taste Acuity
Description: -Baseline, interim assessment (14-42 days post-surgery), day 1 of radiation, day 21 of radiation, day 36 of radiation, 6 weeks after completion of adjuvant therapy, 4 months after the completion of adjuvant therapy, 6 months after the completion of adjuvant therapy, 12 months after the completion of adjuvant therapy, and 24 months after completion of adjuvant therapy