Study: NCT02994082

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tailored behavioral intervention
Description: Participants will receive a standard six session cognitive behavioral intervention for smokeless tobacco cessation combined with supplemental treatment modules based on individual need and preferences.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral activation for elevated depressive symptoms
Description: Participants with elevated depressive symptoms may receive this six session telephone-based behavioral activation intervention.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Post-cessation weight gain management
Description: Participants with concerns about gaining weight after quitting smokeless tobacco use may receive this six session telephone-based behavioral self-management intervention designed to help attenuate post-cessation weight gain.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol use risk reduction
Description: Participants engaging in risky alcohol use may receive this six session telephone-based behavioral intervention for reducing alcohol use.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy - transdermal nicotine patch
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy - nicotine lozenge
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine replacement therapy - nicotine gum
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupropion sustained release
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Varenicline
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination nicotine replacement therapy
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications. Possible combinations include nicotine patch + nicotine lozenge and nicotine patch + nicotine gum.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination nicotine replacement therapy + bupropion
Description: Medication selection will be based on individual participant preferences, medical history, and contraindications. Possible combinations include nicotine patch + bupropion, nicotine gum + bupropion, and nicotine lozenge + bupropion.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tobacco quit line
Description: Referral to the Department of Veterans Affairs tobacco telephone quit line.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational materials
Description: Information regarding the VA tobacco quit line and associated treatment services, self-help materials for tobacco cessation, and information about tobacco cessation medications available in the VA,