TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03507426

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Retrobulbar block
Description: Patients will receive a single retrobulbar injection with 3-4ml of an equal mixture of Lidocaine 2% \& Bupivacaine 0.5% + Hyaluronidase (10 IU/ml), after induction of general anesthesia.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine
Description: Patients will receive a 0.5 mg/kg bolus followed by an infusion of 0.25 mg/kg/h of intravenous Ketamine, after induction of general anesthesia.
Study: NCT02503241

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PEEP INCREMENTAL
Description: PEEP was progressively increased by steps of 2 cmH2O every 60 second until the end-expiratory transpulmonary pressure became positive between 0-2 cmH2O.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PEEP INCREMENTAL
Description: PEEP was progressively increased by steps of 2 cmH2O every 60 second until the end-expiratory transpulmonary pressure became positive between 0-2 cmH2O.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PEEP DECREMENTAL
Description: Lung recruitment maneuver (LRM) is a transitory and controlled increase in airway pressure to open collapsed alveoli. LRM is the first step of the PEEP DECREMENTAL method. After LRM, PEEP is systematically decreased, in small decrements, until the best respiratory system mechanics is identified.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PEEP DECREMENTAL
Description: Lung recruitment maneuver (LRM) is a transitory and controlled increase in airway pressure to open collapsed alveoli. LRM is the first step of the PEEP DECREMENTAL method. After LRM, PEEP is systematically decreased, in small decrements, until the best respiratory system mechanics is identified.
Study: NCT02470780

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifaximin
Description: Rifaximin is an antibiotic used to treat SIBO. It is a 7-day course of treatment followed by three or six months of follow-up. This is a placebo-controlled study designed so that all participants will receive the active drug at least once during the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifaximin
Description: Rifaximin is an antibiotic used to treat SIBO. It is a 7-day course of treatment followed by three or six months of follow-up. This is a placebo-controlled study designed so that all participants will receive the active drug at least once during the study.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo matching Rifaximin treatment.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo matching Rifaximin treatment.
Study: NCT02159040

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Azacitidine
Description: SC or IV AZA at 75mg/m2 7 days/28 day cycle

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine plus Deferasirox
Description: SC or IV AZA at 75mg/m2 7 days/28 day cycle DFX 10mg/kg/day
Study: NCT01624077

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Regulatory T cells
Description: Tregs will inject after liver transplantation
Study: NCT00819702

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Model Care
Description: The Model Care provided training to pediatric health care providers to assess parental psychosocial risk factors to child maltreatment.
Study: NCT03614260

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Paradise Renal Denervation System
Description: Following renal angiogram according to standard procedures, subjects remain blinded and are immediately treated with the renal denervation procedure after randomization.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Renal Angiogram
Description: Following renal angiogram to standard procedures, subjects remain blinded and renal angiogram is considered the sham procedure.
Study: NCT02028325

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorescein Sodium
Description: All patients enrolled in the study will prepare for surgery as per standard neurosurgical indications, procedures and institution protocols. At the time of the anesthesia induction, with the patient under general anesthesia, Fluorescein Sodium 10% (100mg/1mL) at a dose of 3-20 mg/kg will be administered intravenously (the optimal dosage will be determined within the study as the most minimal dose for adequate visualization will be used). For vascular lesions, fluorescein sodium 10% (100mg/1mL) will be injected and used to assess its application after the conventional methods have confirmed the exclusion of the aneurysm. No patient's care will be affected by the results of the Fluorescein angiography.
Study: NCT01871337

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Paula method
Description: The Paula method will be taught to the participants by several registered Paula instructors. Subjects allocated to this intervention will receive one 45-minute group session per week for 12 weeks (with up to 30 minutes for personal questions regarding the exercises). This length of time is crucial because it has been demonstrated that it take three months for women to adequately learn the exercises in order for them to practice independently at home. Participants will be encouraged to practice daily for 15 minutes and report their at- home training.
Study: NCT04653233

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D Systems Touch Haptic Simulator
Description: This simulator is computer-aided and allows us to see this application on the computer screen while practicing with a haptic arm. It gives real-like feedback in hand manipulations. The simulator has a choice of 45 minutes of full instruction, 5 minutes of haptic arm only, or the option.
Study: NCT05715749

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In-home body weight support harness system
Description: A portable, adjustable body weight support harness system that occupies roughly 9 feet x 9 feet space in the home. The system allows 360 degrees of mobility anywhere within the footprint of the frame. The amount of body weight support is adjustable.
Study: NCT03495973

Intervention type: DRUG
Intervention: Ustekinumab
Description: Participants that are initiated on treatment with ustekinumab and are registered in Swibreg will be recruited into the cohort. All aspects of treatment and clinical management of participants will be in accordance with local clinical practice and applicable local regulations, and at the discretion of the participating physician.
Study: NCT03362983

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CareHND
Description: Multidisciplinary, integrated, person-centered care at the integrated HND-clinic
Study: NCT03392168

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARQ-151 cream 0.5%
Description: 0.5% active concentration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARQ-151 cream 0.5%
Description: 0.5% active concentration

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARQ-151 cream 0.15%
Description: 0.15% active concentration

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: ARQ-151 vehicle cream
Description: Vehicle cream
Study: NCT04341129

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abbreviated MRI protocol: initial experience with Dotarem® (Gadoterate Meglumine)
Description: To test the diagnostic effectiveness of an abbreviated MRI to a full MRI in the evaluation of breast lesions using Dotarem
Study: NCT03101202

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SSD tube
Description: The SSD tube allows the suction of subglottic secretions that collect above the cuff of the endotracheal tube
Study: NCT03128281

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaires
Description: Questionnaires completed 30 days before surgery, two (2) hours after surgery, when leaving the post-anesthesia care unit (PACU), and at hospital discharge.~Questionnaires ask about pain level and any drugs taken for it. It should take about 5 minutes to complete.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: Questionnaires completed 30 days before surgery, two (2) hours after surgery, when leaving the post-anesthesia care unit (PACU), and at hospital discharge.~Questionnaires ask about pain level and any drugs taken for it. It should take about 5 minutes to complete.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: Questionnaires completed 30 days before surgery, two (2) hours after surgery, when leaving the post-anesthesia care unit (PACU), and at hospital discharge.~Questionnaires ask about pain level and any drugs taken for it. It should take about 5 minutes to complete.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional Insufflation System (CIS)
Description: CIS with pressure target of 15±1 mmHg used for pneumoperitoneum during laparoscopic/robotic surgery.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ConMed AirSeal Insufflation System (AIS) at Low Pressure
Description: AIS with an insufflation pressure target of 9±1 mmHg used for pneumoperitoneum during laparoscopic/robotic surgery.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ConMed AirSeal Insufflation System (AIS) at Higher Pressure
Description: AIS with an insufflation pressure target of 15±1 mmHg used for pneumoperitoneum during laparoscopic/robotic surgery.
Study: NCT02744248

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IOP Injection
Description: IOP Injection 20 mg Fe/ml, intravenous injection

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% normal saline
Description: 0.9% normal saline 10 ml, intravenous injection
Study: NCT01724034

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abolish Lung Sliding
Description: If there is no lung sliding, the patient will be promptly evaluated for pneumothorax or mainstream intubation.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal Lung Ultrasound
Description: If the patient fails the spontaneous breathing trial and the lung ultrasound examination is normal - researchers will investigate venous thrombosis (deep vein thrombosis and/or pulmonary embolism) and rule out reversible airway obstruction. If the patient has the previous diagnosis of COPD, non invasive mechanical ventilation is indicated for facilitate weaning.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary Interstitial Syndrome
Description: If lung ultrasound shows B pattern - cardiogenic pulmonary edema will be differentiated from Acute Respiratory Distress Syndrome (ARDS). If cardiogenic edema is a possibility, diuretics will be administrated (at least 40 mg of furosemide) or ultrafiltration will be performed. The main target is a negative fluid balance of, at least, 1000 ml before the next spontaneous breathing trial. Another possibility is to titrate vasodilators (at least a 20% reduction in the systolic blood pressure) before the next spontaneous breathing trial.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Asymmetrical Lung Ultrasound
Description: If lung ultrasound shows asymmetrical findings, the occurence of new or uncontrolled infection (pulmonary or extrapulmonary) will be investigated.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Simple Pleural Effusion
Description: If the patient has pleural effusion without ultrasonographic signs of complications (any hyperechoic pattern or complex septated pattern), researchers will administrate diuretics (at least 40 mg of furosemide in 24 hours) or increase ultrafiltration - to achieve a negative fluid balance of, at least, 1000 ml before the next spontaneous breathing trial. Another possibility is to perform pleural drainage.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Complex Pleural Effusion
Description: If there is pleural effusion with hyperechoic or septated pattern, another image exam will be performed and evaluated by the surgical team.
Study: NCT02847390

Intervention type: OTHER
Intervention: Education intervention
Description: The investigators will develop and deliver a diabetes physician and nursing inpatient diabetes superuser educational curriculum focused on delivering safe, evidence-based diabetes care in the hospital setting. The physician educational curriculum will consist of 10 case-based modules taught to internal medicine residents at two academic hospitals and taught to hospitalists at two academic hospitals and one community hospital. The nursing educational curriculum will consistent of 12 case-based modules taught to unit-based nurses at two academic hospitals and one community hospital. These educational interventions will be delivered over a 6-month time frame from August 2016-April 2017.
Study: NCT03931759

Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: laparoscopic surgery
Description: patients with diabetes mellitus in laparoscopic surgery
Study: NCT03610347

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bare metal Stent plus Paclitaxel Balloon

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Drug Eluting Stent
Study: NCT02437942

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biomechanics led physical therapy rehabilitation
Description: Rehabilitation intervention will consist of movement control (3 days per week), whole body strength and power (2 days per week), linear running mechanics (3 days per week), multi-directional mechanics (3 days per week), conditioning sessions (2 days per week). Rehabilitation will continue until physical therapist deems the athlete ready to return to sport.
Study: NCT01543542

Intervention type: RADIATION
Group type: OTHER
Intervention: Whole Brain XRT 30Gy/10 fractions with
Description: 30 Gy of whole brain external beam radiation delivered in 10 fractions. Simultaneous in-field boost of brain lesions to 60 Gy.
Study: NCT01195623

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: preoperative duplex examination

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Preoperative duplex
Study: NCT06126679

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 1-year dietary and physical activity intervention of childhood obesity
Description: The 1-year lifestyle intervention includes intensive, family-based diet and physical activity counselling. Children with their parents meet the pediatrician two times, the specialist nurse five times and the clinical nutritionist three times during the 1-year intervention. One of the meetings with the clinical nutritionist is only for parents and the child is with the nurse at the same time.~The participants in the intervention group are advised and motivated to increase their regular daily physical activity and to reduce sedentary habits. They have one group session for the training in the gymnasium with physical education instructor. The physical education instructor gives a voluntary lecture for parents about increasing physical activity and reducing sedentary time.
Study: NCT02499523

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: THR with conventional technique
Description: THR with conventional technique.
Study: NCT03695263

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Choice of one of five behavioral interventions
Description: All participants will choose one of the five intervention options.
Study: NCT02499523

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: THR with Acetabular Cup Orientation Guides (ACOG)
Description: THR with the ACOG System.
Study: NCT04557358

Intervention type: OTHER
Intervention: COVID-19 survey
Description: A questionnaire locally developed to explore access to medical care and to medications, access to communication with their primary rheumatologist, and patients risk perception about COVID-19 disease

Intervention type: OTHER
Intervention: RAPID-3
Description: The instrument measures function, pain, and patient global estimate of status, with correspond to activity disease

Intervention type: OTHER
Intervention: WHOQOL-BREF
Description: The instrument measures the patient´s quality of life (4 dimensions: physics, phycological, social, and environment)

Intervention type: OTHER
Intervention: DASS-21 instrument (depression and anxiety)
Description: The instrument measures the presence of depression and anxiety
Study: NCT02830412

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Postoperative nausea and vomiting (PONV) reminder
Description: The postoperative nausea and vomiting (PONV) electronic reminder will be programmed to assess the patient risk for PONV according to the risk factors identified by Apfel and Koivuranta. The PONV risk assessment and current guidelines will be displayed electronically for patients randomized to receive the reminder.
Study: NCT00101868

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Discharge communication software
Description: Computerized physician order entry software used by discharging physician

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care discharge process
Description: Handwritten
Study: NCT01619878

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemether-lumefantrine (COA566)
Description: One dispersible tablet taken orally twice a day during 3 days.
Study: NCT02155699

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise 1
Description: 65% of VO2max and 2 sessions per week

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise 2
Description: 85% intensity and 3 sessions per peek
Study: NCT01167400

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cybercycling
Description: exercising on a videogame-enhanced interactive 3D stationary bicycle for 3 months, 3-5x/wk

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional exercise
Description: exercising on a traditional stationary bike for 3 months, 3-5x/wk
Study: NCT02619097

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegol-sihematide injection
Description: single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegol-sihematide injection
Description: single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegol-sihematide injection
Description: single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegol-sihematide injection
Description: single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegol-sihematide injection
Description: single dose
Study: NCT03839394

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telephone
Description: A series of educational pamphlets on CVD risk reduction plus a telephone-based CVD risk reduction curriculum will be administered by Clinic-Based Case Managers (CCMs). Six modules will be given over 24 weeks in a rotating fashion on topics relevant to CVD risk. Subjects will be given the pamphlets every 2 weeks corresponding with the first time they receive the telephone - based module.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Educational pamphlets
Description: A series of 6 handouts will be given to controls once monthly over 6 months on the same topics presented in the telephone modules. Educational packets will be primarily drawn from free printed material available at www.learningaboutdiabetes.org and the American Heart Association website.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational pamphlets
Description: A series of 6 handouts will be given to controls once monthly over 6 months on the same topics presented in the telephone modules. Educational packets will be primarily drawn from free printed material available at www.learningaboutdiabetes.org and the American Heart Association website.
Study: NCT00941304

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxycodone
Description: Single-dose of over-encapsulated oral 5-mg oxycodone capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buprenorphine
Description: Single-dose of buprenorphine HCl buccal film

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buprenorphine
Description: Single-dose of buprenorphine HCl buccal film

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buprenorphine
Description: Single-dose of buprenorphine HCl buccal film

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Film
Description: Single-dose of placebo buccal film

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Film
Description: Single-dose of placebo buccal film

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Film
Description: Single-dose of placebo buccal film

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Film
Description: Single-dose of placebo buccal film

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo Film
Description: Single-dose of placebo buccal film

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Capsule
Description: Single-dose of oral placebo capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Capsule
Description: Single-dose of oral placebo capsule

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Capsule
Description: Single-dose of oral placebo capsule

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Capsule
Description: Single-dose of oral placebo capsule
Study: NCT05923710

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary anterior cruciate ligament repair
Description: Only arthroscopic primary anterior cruciate ligament repair was performed in patients with proximal anterior cruciate ligament tear.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary anterior cruciate ligament repair
Description: Only arthroscopic primary anterior cruciate ligament repair was performed in patients with proximal anterior cruciate ligament tear.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band
Description: In addition to primary anterior cruciate ligament repair, lateral extraarticular tenodesis was performed using the iliotibial band.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band
Description: In addition to primary anterior cruciate ligament repair, lateral extraarticular tenodesis was performed using the iliotibial band.
Study: NCT00595543

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bromfenac
Description: 1 drop (in the eye) Instill one drop in the affected eye twice daily for three months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketorolac
Description: 1 drop (in the eye) Instill one drop in the affected eye four times daily for three months

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Diclofenac
Description: 1 drop (in the eye) Instill one drop in the affected eye four times daily for three months