Study: NCT02609724

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Information
Description: During intensive phase: a leaflet with information about the lymphatic system and lymphoedema, clinical evaluation and conservative treatment of lymphoedema During maintenance phase: two informational sessions about self-management and about compression sleeves and other compression material

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Information
Description: During intensive phase: a leaflet with information about the lymphatic system and lymphoedema, clinical evaluation and conservative treatment of lymphoedema During maintenance phase: two informational sessions about self-management and about compression sleeves and other compression material

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information
Description: During intensive phase: a leaflet with information about the lymphatic system and lymphoedema, clinical evaluation and conservative treatment of lymphoedema During maintenance phase: two informational sessions about self-management and about compression sleeves and other compression material

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Skin care
Description: The skin is hydrated during the session. If wounds are present, the wound is cared.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Skin care
Description: The skin is hydrated during the session. If wounds are present, the wound is cared.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Skin care
Description: The skin is hydrated during the session. If wounds are present, the wound is cared.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Compression therapy
Description: During intensive phase: application of multi-layer, multi-component bandages During maintenance phase: wearing custom-made compression garment

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Compression therapy
Description: During intensive phase: application of multi-layer, multi-component bandages During maintenance phase: wearing custom-made compression garment

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Compression therapy
Description: During intensive phase: application of multi-layer, multi-component bandages During maintenance phase: wearing custom-made compression garment

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fluoroscopy-guided MLD
Description: Fluoroscopy-guided MLD is applied on patient-specific lymphatic system (known from lymphofluoroscopy) by applying cleaning techniques on lymph nodes, resorption techniques to stimulate resorption of lymph by lymph capillaries and gliding technique to stimulate transport of lymph through lymph collectors

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional MLD
Description: Traditional MLD is applied without knowledge of the patient-specific lymphatic architecture. During MLD no cream or oil is used. A pressure with the hands up to 40 mmHg is applied. Drainage is performed at the level of the jugular and occipital region and the belly (in the depth). Draining techniques are applied on the retroclavicular lymph nodes, axillary lymph nodes, humeral lymph nodes and cubital lymph nodes. At the level of the hand, arm, shoulder and trunk, hand movements are applied to stimulate lymphatic transport through the lymph collectors. The therapist's hands perform 'pumping-movements' while stretching the skin.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo MLD
Description: During placebo MLD a superficial massage with massage cream is performed on the patient's contralateral arm and on the belly.