TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04056832

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single Strip Pericardium
Description: The anterior pericardium is taken in accordance with the measurements made using an aortic annulus sizer or Ismail sizer. The diameter of the annulus valve is converted to circumference of the aortic valve according as a measure of the length of the pericardium. Measurement of aortic commissure height is done by measuring the distance between the lowest point of the valve attachment to the highest point on the commissure as a measure of pericardium width. The pericardium is immersed in 0.6% glutaraldehyde solution for 10 minutes, then rinsed and soaked with saline solution 3 times for 6 minutes each. After the pericardium becomes firm it is cut to be a single strip according to the length and width in the previous measurement. It is then sutured to the aortic valve annulus.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical Prosthetic Valve
Description: Median incision is performed at the surgical site. Sternal retractor is placed at the sternum after median sternotomy being performed. Aortic valve is measured using aortic annulus sizer. Pledgeted suture is performed for the mattress. Sutures are performed to attach the mechanical prosthetic to the aortic annulus.
Study: NCT00674713

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ondansetron

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Physiological saline solution

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sham acupuncture

Intervention type: DRUG
Group type: OTHER
Intervention: Ondansetron

Intervention type: OTHER
Group type: OTHER
Intervention: Acupuncture at P6 point

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Physiological saline solution

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham acupuncture
Study: NCT02239549

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Jumbo cold forceps polypectomy
Description: The specific jumbo cold forceps used are the Olympus EndoJaw Biopsy Forceps (open jaw diameter 8.5 mm) and the Boston Scientific RJ4 Biopsy Forceps (open jaw diameter 8.8 mm).

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cold snare polypectomy
Description: The specific cold snares used are the Boston Scientific Captiflex Extra Small Oval Flexible Snare (loop width 11 mm), the US Endoscopy Dsnare Dimunitive Polypectomy and Suction System (loop width 9 mm), or the Boston Scientific Sensation Short Throw Oval Flexible Snare (loop width of 13 mm, 27 mm, or 30 mm).
Study: NCT03755128

Intervention type: OTHER
Intervention: No intervention
Description: No investigational drugs will be administered as part of the study
Study: NCT03702881

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bonded Spurs associated with posterior build-ups
Description: Twenty-five patients will be treated with bonded spurs associated with posterior build-ups. The cervical portion of the palatal surfaces of the maxillary incisors and the incisal portion of the lingual surfaces of the mandibular incisors will be pumiced, rinsed, dried, and acid etched with 37% phosphoric acid. The etched surfaces will be subsequently rinsed and carefully dried. Then, the spurs will be bonded using Transbond primer/adhesive. The positions for the spurs will be chose to prevent possible future occlusal interferences The spurs will be sharpened with a carborundum disk before bonding. In addition, posterior build-ups (resin blocks) will be cemented on the functional cusps of all maxillary posterior teeth. The treatment time will be 12 months. After this time, the posterior build ups will be removed and the bonded spurs will be maintained for 12 months more, as active retention.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional bonded spurs
Description: Twenty-five patients will be treated only with bonded spurs. The bonding of the spurs will follow the same protocol described for the experimental group. The treatment time will be 12 months. After this time, the bonded spurs will be maintained for 12 months more, as active retention.
Study: NCT02469545

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactobacillus Plantarum 299v
Description: Administering antidepressant drug (SSRI - selective serotonin reuptake inhibitor) and probiotic - 2x1 caps. per day of Lactobacillus Plantarum 299V (10mld colony forming units in 1 caps.) for 8 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Crystalline cellulose powder
Description: Administering antidepressant drug (SSRI - selective serotonin reuptake inhibitor) and placebo of probiotic - 2x1 placebo caps. filled with micro-crystalline cellulose powder for 8 weeks.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Escitalopram
Description: 5-20mg daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Escitalopram
Description: 5-20mg daily

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sertraline
Description: 50-100mg daily

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sertraline
Description: 50-100mg daily
Study: NCT04367623

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Brain computer interface based therapy
Description: Participants who decide to take part will be assigned to a treatment or a control group. Both groups will have the same assessments and the same number of therapy sessions. Therapy group will have a training that consists of Brain Computer Interface controlled Functional Electrical Stimulation followed by a physical practice of the dominant upper limb, while the control group will have a physical practice only. One experimental session will last about 60 min for both groups (including setup and therapy) and participants in each group will receive 20 sessions, about 3 times per week. The expected time needed for completion of 20 sessions is 7 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Brain computer interface based therapy
Description: Participants who decide to take part will be assigned to a treatment or a control group. Both groups will have the same assessments and the same number of therapy sessions. Therapy group will have a training that consists of Brain Computer Interface controlled Functional Electrical Stimulation followed by a physical practice of the dominant upper limb, while the control group will have a physical practice only. One experimental session will last about 60 min for both groups (including setup and therapy) and participants in each group will receive 20 sessions, about 3 times per week. The expected time needed for completion of 20 sessions is 7 weeks
Study: NCT01423747

Intervention type: DRUG
Group type: OTHER
Intervention: VP16
Description: patients with MSD receive as conditioning VP16 60mg/kg/d on day -3

Intervention type: RADIATION
Group type: OTHER
Intervention: TBI
Description: patients with a MSD receive TBI (12Gy in 6 fractions) as conditioning

Intervention type: DRUG
Group type: OTHER
Intervention: VP16, ATG
Description: patients with a HLA matched unrelated Donor (9/10 oder 10/10) receive VP16 60mg/kg/d on day -3 and ATG fresenius 20mg/kg/d on day -3,-2,-1

Intervention type: RADIATION
Group type: OTHER
Intervention: TBI
Description: patients with a HLA matched unrelated Donor (9/10 oder 10/10) receive TBI (12Gy in 6 fractions)

Intervention type: DRUG
Group type: OTHER
Intervention: Fludarabine, OKT3, Treosulfan, Thiotepa
Description: patients with a MMD (haploidentical or cord blood) receive Fludarabine 30mg/m²/d on day -9 to -5, ATG 20mg/kd/d on day -3 to day -1, Treosulfan 14g/m²/d on day -7 to -5 and Thiotepa 2x5mg/kg/d on day -4

Intervention type: DRUG
Group type: OTHER
Intervention: VP16, ATG
Description: patients with MMD-transplantation (8/10)receive VP16 60mg/kg/d on day -4, ATG from day -3 to day-1 20mg/kg/d

Intervention type: RADIATION
Group type: OTHER
Intervention: TBI
Description: patients with a MMD-transplantation (8/10) receive 12 Gy in 6 fractions
Study: NCT00567398

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dianeal
Description: Dianeal 1.5% Dextrose (1.38% Glucose), 2.5% Dextrose (2.27% Glucose), 4.25% Dextrose (3.86% Glucose)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Physioneal
Description: Physioneal 40 or Physioneal 35

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Extraneal
Description: Extraneal - 7.5% Icodextrin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nutrineal
Description: Nutrineal - 1.1% Amino Acids
Study: NCT01118000

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: limb ischemia preconditioning
Description: limb ischemic preconditioning consists of three 5-min cycles of left upper limb ischemia induced by a blood pressure cuff placed on the left upper arm and inflated to 200 mmHg,with an intervention 5-min of reperfusion during which the cuff was deflated.
Study: NCT00587496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: valacyclovir hydrochloride
Description: 500 mg capsule, one per day for 30 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo
Description: lactose placebo capsule, six per day for 30 days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: valacyclovir plus aspirin
Description: 500 mg valacyclovir capsule, one per day for 30 days 325 mg acetyl salicylic acid (aspirin) capsule, three per day for 30 days placebo capsule, two per day for 30 days
Study: NCT01402102

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Aged garlic powder
Description: Aged garlic powder(6.0g/day)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo powder
Description: Placebo powder(6.0g/day)
Study: NCT03264729

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Isometric exercise
Description: The isometric exercise is performed standing with the forefoot on a step. The participant is instructed to stand still with the ankle joint in neutral and hold this position. Supporting oneself for balance by placing the hands on a wall or a rail is allowed. The participant performs 5 sets of 45-second isometric holds. The load used is the heaviest possible load that the participant is able to withstand for 1 minute. As with the isotonic exercise, if the participant's body weight is inadequate the participant is fitted with a backpack with books and/or weights.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Isotonic exercise
Description: The isotonic exercise is performed standing with the forefoot on a step. The toes are maximally dorsi-flexed by placing a towel underneath them. The participant is instructed to perform a heel-raise to a maximal plantar flexion in the ankle joint, and afterwards to lower the heel to maximal dorsi flexion. Supporting oneself for balance by placing the hands on a wall or a rail is allowed. The participant performs 4 sets of 8 repetitions with a load of 8RM. The contraction time is 3s concentric, 2s isometric and 3s eccentric and will be guided by a metronome.~If the participant's body weight is inadequate to reach sufficient loading during the exercises the participant is fitted with a backpack with books and/or weights.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walking
Description: The walking will be performed barefoot and the participant will be instructed in walking at a pace similar to the pace they would use when walking around in their home. The duration of the walking session will be four minutes to match the duration during the exercises.
Study: NCT02214394

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-performance liquid chromatography Analysis
Description: Blood samples will be collected for HPLC analysis to compare with the breath samples.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SMART Device
Description: Breath collection for GC-MS analysis to compare with Blood collection.
Study: NCT01452841

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Grapefruit
Description: 1.5 Rio Red Grapefruit consumed daily for 6 weeks

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants followed a diet low in bioactive rich fruits and vegetables and avoided citrus for six weeks
Study: NCT01344525

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic gastric sleeve
Description: Laparoscopic gastric sleeve

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Gastric Banding
Description: Gastric Banding

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multidisciplinary lifstyle intervention
Description: Multidisciplinary lifstyle intervention (OPTIFAST®52-program)

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Roux-en-Y Bypass
Description: Roux-en-Y Bypass
Study: NCT02216604

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimodal Exercise Intervention
Description: During their inpatient hospitalization the participants perform 3-5x weekly guided training sessions about 15-30min. The intervention includes: game console-based training using Nintendo Wii® (endurance, strength endurance and balance), age-specific resistance training and sessions of body awareness. During the outpatient phases the participants perform a home-based exercise training 3-5x weekly using a training manual. In addition, the patients obtain a movement diary and a pedometer for documenting their activity level.
Study: NCT05808569

Intervention type: BEHAVIORAL
Intervention: Test
Description: A specific self-test composed by 16 questions , will be administered to BC patients undergoing adjuvant RT.
Study: NCT02223858

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive Activities (PA) Program
Description: 6-week program of at-home activities (1 per week) that have been shown to increase positivity. Activities were delivered via activity booklets and oral instructions provided during weekly telephone calls from trained interventionists. Interventionist oriented participants to the booklets and reviewed the first activity at the end of an in-person baseline visit. Booklets contained all instructions patients needed to complete the full program. Interventionists also provided support via weekly calls in which they assessed completion of the previous week's activity, reviewed instructions for the next activity, and helped participants trouble-shoot anticipated barriers.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attention Control (AC) Program
Description: 6-week program of at-home activities (1 per week) based on affectively neutral activities from control conditions in studies of positive activities interventions. Activities were delivered via activity booklets and oral instructions provided during weekly telephone calls from trained interventionists. Interventionist oriented participants to the booklets and reviewed the first activity at the end of an in-person baseline visit. Booklets contained all instructions patients needed to complete the full program. Interventionists also provided support via weekly calls in which they assessed completion of the previous week's activity, reviewed instructions for the next activity, and helped participants trouble-shoot anticipated barriers.
Study: NCT02901704

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Renal Denervation System (AngioCare)
Description: After a renal angiography according to standard procedures, subjects remain blinded and are immediately treated with the renal denervation procedure after randomization.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham procedure
Description: After a renal angiography according to standard procedures, subjects remain blinded and remain on the catheterization lab table for at least 10 minutes prior to introducer sheath removal.
Study: NCT04936087

Intervention type: OTHER
Group type: OTHER
Intervention: The World Health Organization 8 steps for manual wheelchair service delivery
Description: All study participants were provided with a new wheelchair, a wheelchair cushion, and wheelchair services, delivered by trained wheelchair service providers, according to the WHO 8-step wheelchair service delivery process including assessment, fitting, and a 30-minute individual or group training on 7 wheelchair skills, device care, and pressure injury prevention techniques. Additionally, wheelchair maintenance reminders were sent through a text message service (SMS) to a sub-cohort of participants.~Wheelchair users were provided with one of three different, International Standards Organization (ISO) tested, wheelchair models according to the users' needs and availability: standard, active, and all-terrain models. All wheelchairs were provided with a basic contour cushion made of polyurethane foam. However, whenever a risk of pressure injury was identified for a study participant, wheelchair providers fabricated a pressure-relief cushion.
Study: NCT03338127

Intervention type: DIAGNOSTIC_TEST
Intervention: renal function test
Description: 2 ml blood sample to be investigated for renal function test
Study: NCT00194493

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ESRA-C
Description: Graphical summary of patient symptoms and quality of life
Study: NCT02288455

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GTU Artificial Urinary Sphincter
Description: A totally implantable Artificial Urinary Sphincter (AUS) for the treatment of male Stress Urinary Incontinence (SUI)
Study: NCT01254708

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ambisome ®
Description: liposomal amphotericin B

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Regular standard of care medication
Description: Drug for this group is at the physician's discretion. Patients in this group receive the standard of care medication currently implemented at the Institution. Example would be voriconazole
Study: NCT01984528

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: four differente concentrations of Alternaria alternata allergen extract, positive control and negative control
Description: This concentrations will be tested in every patient in duplicate on the volar surface of the forearm.
Study: NCT01094145

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Deep brain stimulation
Description: DBS in the Nucleus basalis Meynert

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Deep brain stimulation
Description: DBS in the Nucleus basalis Meynert
Study: NCT04422158

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nuun electrolyte tablet
Description: Each table contains 2 grams of carbohydrate and a combination of electrolytes. calcium (13mg, 1%DV), sodium (300mg, 13%DV), potassium (150mg, 3%DV), magnesium (25mg, 6%DV), and chloride (40mg, 2%DV).

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nuun electrolyte tablet
Description: Each table contains 2 grams of carbohydrate and a combination of electrolytes. calcium (13mg, 1%DV), sodium (300mg, 13%DV), potassium (150mg, 3%DV), magnesium (25mg, 6%DV), and chloride (40mg, 2%DV).

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: water
Description: water

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: water
Description: water

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: water
Description: water
Study: NCT02465827

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nerve block with ropivacaine
Description: Ultrasound guided nerve blocks of the saphenous and obturator nerve, posterior branch with ropivacaine 0.75% for both nerve branches

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nerve block with ropivacaine and with saline
Description: nerve blocks of the saphenous nerve with ropivacaine 0.75% and obturator nerve, posterior branch with saline

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: nerve block with saline
Description: Ultrasound guided nerve blocks of the saphenous and obturator nerve, posterior branch with saline for both nerve branches
Study: NCT01644357

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmaceutical care
Description: Pharmacist intervention, focused on the optimization of drug therapy, identification and resolution of drug related problems, resulting in best asthma control and quality of life. Pharmacists document their initial and monthly follow up encounters using a specified form. An action plan for self management of these patients was prepared and discussed aiming at early identification and treatment of an exacerbation episode. Meetings will be held weekly with intervention team to discuss action plan and measure of outcomes of all problems identified.
Study: NCT05155514

Intervention type: PROCEDURE
Intervention: Mobil-O-Graph PWA
Description: After resting in a quiet room preoperatively, blood pressure was measured on the right arm using an oscillometric method.

Intervention type: PROCEDURE
Intervention: Mobil-O-Graph PWA
Description: After resting in a quiet room preoperatively, blood pressure was measured on the right arm using an oscillometric method.
Study: NCT00473382

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ranibizumab
Description: Sterile solution for intravitreal injection.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ranibizumab
Description: Sterile solution for intravitreal injection.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Sham injection
Study: NCT01019083

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be given according to randomization list

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be given according to randomization list

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Control will be selected from the Arsenic non contaminated Area

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zinc Sulphate
Description: Zinc Sulphate will be given according to randomization list

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albendazole and Secnidazole
Description: Albendazole and Secnidazole will be given according to randomization list

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Arsenic
Description: Participant will be selected from the Arsenic Contaminated Area
Study: NCT03588884

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcifediol Oral Capsule
Description: Capsule, daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcifediol Oral Product
Description: Capsule, once a month

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cholecalciferol
Description: Capsule, once a month

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cholecalciferol
Description: Capsule, once a month

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paricalcitol Oral Capsule
Description: Capsule, daily
Study: NCT01302249

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Latanoprost 0.005%
Description: q.d.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Latanoprost 0.005%
Description: q.d.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AR-12286 Ophthalmic Solution 0.5%

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Timolol maleate ophthalmic solution 0.5%