Study: NCT03519867

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-8616
Description: MK-8616 will be administered at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg/kg iv as a 30-second infusion. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zemuron®
Description: Zemuron® (0.6 or 1.2 mg/kg, iv) will be administered as a 10-second bolus infusion to achieve 1 to 2 PTCs. If needed, a maintenance dose of 0.15 mg/kg will be given. Doses are based on actual body weight.