Study: NCT03641768

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: You will be asked to undergo a scan of your brain called an MRI. The MRI scan can measure the functioning of your brain.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: You will be asked to undergo a scan of your brain called an MRI. The MRI scan can measure the functioning of your brain.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: You will be asked to undergo a scan of your brain called an MRI. The MRI scan can measure the functioning of your brain.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: You will be asked to undergo a scan of your brain called an MRI. The MRI scan can measure the functioning of your brain.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PET
Description: You will be asked to undergo a scan of brain called a positron emission tomography (PET) scan. The PET scan is a test that uses radioactive glucose (sugar) and a computer to create images of how your brain is functioning. Abnormal cells in the body use glucose at a different rate than normal cells and this allows the scanner to create a detailed picture of how your body is working.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PET
Description: You will be asked to undergo a scan of brain called a positron emission tomography (PET) scan. The PET scan is a test that uses radioactive glucose (sugar) and a computer to create images of how your brain is functioning. Abnormal cells in the body use glucose at a different rate than normal cells and this allows the scanner to create a detailed picture of how your body is working.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PET
Description: You will be asked to undergo a scan of brain called a positron emission tomography (PET) scan. The PET scan is a test that uses radioactive glucose (sugar) and a computer to create images of how your brain is functioning. Abnormal cells in the body use glucose at a different rate than normal cells and this allows the scanner to create a detailed picture of how your body is working.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PET
Description: You will be asked to undergo a scan of brain called a positron emission tomography (PET) scan. The PET scan is a test that uses radioactive glucose (sugar) and a computer to create images of how your brain is functioning. Abnormal cells in the body use glucose at a different rate than normal cells and this allows the scanner to create a detailed picture of how your body is working.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 18F-Florbetapir
Description: At the Duke University PET Center you will be in a quiet dimly lit space with only ambient room sound, with your eyes open and ears unplugged. Your safety will be monitored by a physician and nurse. 18F-florbetapir will be administered to you as a bolus injection through a peripheral vein followed by a flush and 10 minute continuous brain PET imaging will begin 50 minutes post-injection.