Study: NCT00493220

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC HYLENEX and Ceftriaxone
Description: single, subcutaneous, 150 U dose of HYLENEX; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC HYLENEX and Ceftriaxone
Description: single, subcutaneous, 150 U dose of HYLENEX; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC HYLENEX and Ceftriaxone
Description: single, subcutaneous, 150 U dose of HYLENEX; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC HYLENEX and Ceftriaxone
Description: single, subcutaneous, 150 U dose of HYLENEX; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC HYLENEX and Ceftriaxone
Description: single, subcutaneous, 150 U dose of HYLENEX; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC HYLENEX and Ceftriaxone
Description: single, subcutaneous, 150 U dose of HYLENEX; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC Placebo and Ceftriaxone
Description: single, subcutaneous injection of 1 mL 0.9% sodium chloride solution; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC Placebo and Ceftriaxone
Description: single, subcutaneous injection of 1 mL 0.9% sodium chloride solution; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC Placebo and Ceftriaxone
Description: single, subcutaneous injection of 1 mL 0.9% sodium chloride solution; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC Placebo and Ceftriaxone
Description: single, subcutaneous injection of 1 mL 0.9% sodium chloride solution; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC Placebo and Ceftriaxone
Description: single, subcutaneous injection of 1 mL 0.9% sodium chloride solution; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SC Placebo and Ceftriaxone
Description: single, subcutaneous injection of 1 mL 0.9% sodium chloride solution; followed by single, subcutaneous, 1 gm dose of ceftriaxone (350 mg/mL solution administered at 2.5 mL/min over 1.14 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Ceftriaxone
Description: single, intravenous infusion of 1 gm ceftriaxone (40 mg/mL solution administered at 0.83 mL/min over 30 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Ceftriaxone
Description: single, intravenous infusion of 1 gm ceftriaxone (40 mg/mL solution administered at 0.83 mL/min over 30 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Ceftriaxone
Description: single, intravenous infusion of 1 gm ceftriaxone (40 mg/mL solution administered at 0.83 mL/min over 30 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Ceftriaxone
Description: single, intravenous infusion of 1 gm ceftriaxone (40 mg/mL solution administered at 0.83 mL/min over 30 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Ceftriaxone
Description: single, intravenous infusion of 1 gm ceftriaxone (40 mg/mL solution administered at 0.83 mL/min over 30 minutes)

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IV Ceftriaxone
Description: single, intravenous infusion of 1 gm ceftriaxone (40 mg/mL solution administered at 0.83 mL/min over 30 minutes)