Study: NCT04439370

Intervention type: DIAGNOSTIC_TEST
Intervention: Microneurography to measure muscle sympathetic nerve activity (MSNA)
Description: Microneurography is a direct measurement of electrical activity of peripheral sympathetic nerves

Intervention type: DIAGNOSTIC_TEST
Intervention: Microneurography to measure muscle sympathetic nerve activity (MSNA)
Description: Microneurography is a direct measurement of electrical activity of peripheral sympathetic nerves

Intervention type: DIAGNOSTIC_TEST
Intervention: Microneurography to measure muscle sympathetic nerve activity (MSNA)
Description: Microneurography is a direct measurement of electrical activity of peripheral sympathetic nerves

Intervention type: DIAGNOSTIC_TEST
Intervention: Microneurography to measure muscle sympathetic nerve activity (MSNA)
Description: Microneurography is a direct measurement of electrical activity of peripheral sympathetic nerves

Intervention type: DIAGNOSTIC_TEST
Intervention: Baroreflex sensitivity testing
Description: Two arms of the baroreflex that will be tested in this study are sympathetic and cardiovagal. Static baroreflex is tested during baseline resting conditions and dynamic baroreflex is tested during Valsalva maneuvers.

Intervention type: DIAGNOSTIC_TEST
Intervention: Baroreflex sensitivity testing
Description: Two arms of the baroreflex that will be tested in this study are sympathetic and cardiovagal. Static baroreflex is tested during baseline resting conditions and dynamic baroreflex is tested during Valsalva maneuvers.

Intervention type: DIAGNOSTIC_TEST
Intervention: Baroreflex sensitivity testing
Description: Two arms of the baroreflex that will be tested in this study are sympathetic and cardiovagal. Static baroreflex is tested during baseline resting conditions and dynamic baroreflex is tested during Valsalva maneuvers.

Intervention type: DIAGNOSTIC_TEST
Intervention: Baroreflex sensitivity testing
Description: Two arms of the baroreflex that will be tested in this study are sympathetic and cardiovagal. Static baroreflex is tested during baseline resting conditions and dynamic baroreflex is tested during Valsalva maneuvers.

Intervention type: DIAGNOSTIC_TEST
Intervention: Sympathoexcitatory Maneuvers
Description: Cold Pressor Test (CPT) and Upper extremity fatiguing contraction with post exercise circulatory occlusion (PECO) will be performed

Intervention type: DIAGNOSTIC_TEST
Intervention: Sympathoexcitatory Maneuvers
Description: Cold Pressor Test (CPT) and Upper extremity fatiguing contraction with post exercise circulatory occlusion (PECO) will be performed

Intervention type: DIAGNOSTIC_TEST
Intervention: Sympathoexcitatory Maneuvers
Description: Cold Pressor Test (CPT) and Upper extremity fatiguing contraction with post exercise circulatory occlusion (PECO) will be performed

Intervention type: DIAGNOSTIC_TEST
Intervention: Sympathoexcitatory Maneuvers
Description: Cold Pressor Test (CPT) and Upper extremity fatiguing contraction with post exercise circulatory occlusion (PECO) will be performed

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood tests
Description: Serum FSH, estrogen, progesterone, and testosterone will be measured

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood tests
Description: Serum FSH, estrogen, progesterone, and testosterone will be measured

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood tests
Description: Serum FSH, estrogen, progesterone, and testosterone will be measured

Intervention type: DIAGNOSTIC_TEST
Intervention: Blood tests
Description: Serum FSH, estrogen, progesterone, and testosterone will be measured