Study: NCT04274075

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Tablet, Fasted: Treatment A
Description: One dose of the GDC-9545 Phase 1 reference tablet formulation (three 10-mg tablets) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Tablet, Fasted: Treatment A
Description: One dose of the GDC-9545 Phase 1 reference tablet formulation (three 10-mg tablets) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fasted: Treatment B
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fasted: Treatment B
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fasted: Treatment B
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fasted: Treatment B
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fasted: Treatment B
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fasted: Treatment B
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water after at least an 8-hour fast.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fed: Treatment C
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water within 30 minutes of eating a high-fat meal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fed: Treatment C
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water within 30 minutes of eating a high-fat meal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fed: Treatment C
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water within 30 minutes of eating a high-fat meal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fed: Treatment C
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water within 30 minutes of eating a high-fat meal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fed: Treatment C
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water within 30 minutes of eating a high-fat meal.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GDC-9545 Capsule, Fed: Treatment C
Description: One dose of the GDC-9545 Phase 3 capsule formulation (one 30-mg capsule) administered orally with approximately 240 mL room temperature water within 30 minutes of eating a high-fat meal.