TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03768440

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: continuous erector spinae block (ESB)
Description: Erector spinae block: T4/5 transverse process is identified with the ultrasound transducer in a parasagittal orientation; the needle tip is advanced until it contacts the transverse process, just below the erector spinae muscle complex; the erector spinae muscle is visualized to be elevated up off of the transverse process with normal saline injection. Following a bolus injection of 2ml/kg of 0.2% ropivacaine, a catheter is threaded into the space occupied by the local anesthetic bolus.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: continuous paravertebral block (PVB)
Description: The paravertebral space (bound medially by the bodies of the vertebrae, intervertebral discs, and intervertebral foraminae; anterolaterally by the parietal pleura and the innermost intercostal membrane; posteriorly by the transverse processes of the thoracic vertebrae, heads of the ribs, and the superior costotransverse ligament) laying between T4/5 is identified using the ultrasound transducer in a transverse orientation; the needle tip is advanced until it is seen passing under the transverse process, immediately superior to the pleura; the pleura is seen to deflect downward with normal saline injection. Following a bolus injection of 2ml/kg of 0.2% ropivacaine, a catheter is threaded into the space occupied by the local anesthetic bolus.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine
Description: Ropivacaine 0.2% will be the drug used for each group (ESB group and PVB group)

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine
Description: Ropivacaine 0.2% will be the drug used for each group (ESB group and PVB group)
Study: NCT03552224

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Recording of auditory nerve activity
Description: near field recording of auditory nerve activity with contact electrode

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Recording of auditory nerve activity
Description: near field recording of auditory nerve activity with contact electrode
Study: NCT03530787

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Acetyl Zingerone Topical Cream
Description: Topical cream with an active acetyl zingerone component.

Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Topical cream
Description: Topical cream without an active acetyl zingerone component and just the carrier cream.
Study: NCT02453217

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chinese CHIP
Description: The CHIP physical health screening tool will be used by community psychiatric nurses in the treatment group to assess patients' physical health risk and identify problematic lifestyle behaviours. The findings from the assessment will be used to devise an individualized care plan with patients. This treatment plan may involve community psychiatric nurses collaborated with psychiatrists, drawing patients attention to indicators of physical health risk by using a traffic light system The community nurses will use motivational interviewing approaches to make patients be aware of their physical health risks and enhance their motivation to adopt healthier behaviours.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment as usual
Description: The routine community mental health care provided by the community psychiatric nursing service and outpatient clinic.
Study: NCT03150992

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Elemental 028 Extra Liquid
Description: A nutritionally complete, liquid elemental diet consisting of a mixture of essential and non-essential amino acids, carbohydrate, fat, vitamins, minerals, trace elements and flavourings with sugars \& sweeteners.
Study: NCT01875627

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Konjac noodles
Description: Replacement of carbohydrate noodles with non-caloric Konjac noodles (viscous gel meal)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Konjac noodles
Description: Replacement of carbohydrate noodles with non-caloric Konjac noodles (viscous gel meal)

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Konjac noodles
Description: Replacement of carbohydrate noodles with non-caloric Konjac noodles (viscous gel meal)

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Carbohydrate and Konjac Noodles

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carbohydrate and Konjac Noodles

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carbohydrate and Konjac Noodles

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Carbohydrate noodles

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carbohydrate noodles

Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carbohydrate noodles
Study: NCT00375050

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Riluzole

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo
Study: NCT01335880

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coupons for use within the next week
Description: Participants who attend an exercise class will receive a coupon for a free exercise class to be used within the next week.

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Coupons for use within the next 3 months
Description: Participants who attend an exercise class will receive a coupon to attend an exercise class for free within the next 3 months.
Study: NCT01654653

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hypertonic sodium lactate
Description: Administered at beginning of surgery as loading dose at 3 mL/kg body weight within 15 minutes. Additional fluid administered if needed and this was was managed similarly in both groups; the types and amount of additional fluid was measured and recorded. Surgery procedure and concomitant medication was managed similarly.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 6% Hydroxy Ethyl Starch
Description: Administered at beginning of surgery as loading dose at 3 mL/kgBW within 15 minutes. Additional fluid given if needed and this was managed similarly in both groups; the types and amount of additional fluid was measured and recorded. Surgery procedure and concomitant medication was managed similarly
Study: NCT02615015

Intervention type: OTHER
Intervention: Blood draw

Intervention type: OTHER
Intervention: Blood draw
Study: NCT00420277

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hemospan (MP4OX)
Description: 250 mL unit dose, up to 500 mL total dose as needed at protocol-defined dosing triggers

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Voluven (HES 130/0.4)
Description: 250 mL unit dose, up to 500 mL total dose as needed at protocol-defined dosing triggers
Study: NCT02952989

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SGN-2FF
Description: SGN-2FF oral daily dosing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SGN-2FF
Description: SGN-2FF oral daily dosing.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pembrolizumab
Description: 200 mg every 3 weeks by IV infusion
Study: NCT03541954

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of lower urinary tract.
Description: Non invasive lower urinary tract sensitivity testing: provoked diuresis with sonographic estimates of sensory thresholds.

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of lower urinary tract.
Description: Non invasive lower urinary tract sensitivity testing: provoked diuresis with sonographic estimates of sensory thresholds.

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of lower rectal tract
Description: Lower digestive tract sensitivity testing: rectal electronic barostat with ascending pressure (phasic distension).

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of lower rectal tract
Description: Lower digestive tract sensitivity testing: rectal electronic barostat with ascending pressure (phasic distension).

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of vulva muscles
Description: Vulvar sensitivity testing: pressure pain threshold evaluated using vulvagesiometer.

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of vulva muscles
Description: Vulvar sensitivity testing: pressure pain threshold evaluated using vulvagesiometer.

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of pelvic muscles
Description: Myofascial sensitivity testing: piriformis, levator ani and obturator internus muscles pressure pain threshold evaluated using intra-vaginal algometer.

Intervention type: OTHER
Group type: OTHER
Intervention: Sensory testing of pelvic muscles
Description: Myofascial sensitivity testing: piriformis, levator ani and obturator internus muscles pressure pain threshold evaluated using intra-vaginal algometer.
Study: NCT01820507

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optiflow (Fisher&Paykel)
Description: The described method of oxygen supply will be maintained continuously for the first 24 hours after extubation.

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasal cannulae or controlled oxygen concentration mask
Description: The described method of oxygen supply will be maintained continuously for the first 24 hours after extubation.
Study: NCT02252900

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Magnetic resonance imaging
Description: All patients will undergo the diagnostic test specific to the study
Study: NCT04543097

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vocational Support
Description: Participants randomised to receive vocational advice will all be offered:~Step 1, contact by phone to undertake an assessment with a trained Vocational Support Worker (VSW) to identify obstacles to Return to Work (RTW) and support RTW planning.~Step 2, face-to-face (in person or by videoconference) in-depth discussion of obstacles to RTW and further support for RTW planning.~Step 3, contact by the VSW (with participant consent) with the participants' workplace.~The frequency of contact will be individualised to the needs of participants and the offer of support continued until sustained RTW (defined as return to any work for at least 4 weeks) or until 6 months of absence, after which participants will be signposted to other services.
Study: NCT01296542

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin Ophthalmic

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Besifloxacin Ophthalmic
Study: NCT00474786

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sorafenib
Description: Subjects randomized to arm B will take sorafenib 400 mg (2 x 200 mg tablets) PO, BID (total daily dose of 800 mg).

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: temsirolimus (Torisel)
Description: Subjects randomized to arm A will receive temsirolimus (Torisel) 25 mg via IV infusion once weekly. This infusion is to be administered over a 30-60 minute period. Subjects are to be pre-treated with 25-50 mg IV diphenhydramine (or comparable IV antihistamine) approximately 30 minutes before temsirolimus infusion.
Study: NCT03885180

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Warfarin Sodium
Description: Extending warfarin anticoagulation
Study: NCT02756780

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tenovus Cancer Choir
Description: Choir sessions will take place at both of the Royal Marsden Hospital sites on a weekly basis. Sessions typically consist of learning popular songs with messages of support. Songs are learnt without sheet music, using specially created backing tracks. These are also made available to participants at home so they can continue singing away from the sessions. No singing experience is required and the main aim of the sessions is enjoyment and meeting other people. Sessions will take place in the early evening so that participants have the option of staying to socialise afterwards.
Study: NCT03369028

Intervention type: OTHER
Intervention: 2D and 3D image of infants´ faces
Description: 2D and 3D image of infants´ faces
Study: NCT00725790

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vardenafil
Description: 10 mg vardenafil on demand treatment for first 4 weeks.~A decision is made at week 4 to either maintain the previous dosage regimen or to up-titrate to 20 mg per dose of vardenafil or down-titrate to 5 mg per dose of vardenafil during the subsequent 4 week double-blind treatment period.~A decision is made at week 8 to either maintain the previous dosage regimen or to up-titrate to 20 mg per dose of vardenafil or down-titrate to 5 mg per dose of vardenafil during the subsequent 4 week double-blind treatment period.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 10 mg placebo on demand treatment for first 4 weeks.~A decision is made at week 4 to either maintain the previous dosage regimen or to up-titrate to 20 mg per dose of placebo or down-titrate to 5 mg per dose of placebo during the subsequent 4 week double-blind treatment period.~A decision is made at week 8 to either maintain the previous dosage regimen or to up-titrate to 20 mg per dose of placebo or down-titrate to 5 mg per dose of placebo during the subsequent 4 week double-blind treatment period.
Study: NCT04537117

Intervention type: OTHER
Intervention: Questionaire
Description: Questionnaire addressing pediatric dentists behaviors and practices during the COVID-19 pandemic
Study: NCT03347734

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eye exercises group
Description: * 20 times hot water, 20 times cold water washing face in the morning and evening.~* Palming; 2 hands are rubbed together and warmed up, and the eyes are closed, and 8 digits are drawn with eyes in darkness.~* 20 blinks~* Looking at a clock in a circular shape, from 12 to 6, from 6 to 12, from 3 to 9, from 9 to 3, from 2 to 8, from 8 to 2, oblique from 10 to 4, from 4 to 10, and turning the eyes starting from 12 clockwise and counterclockwise. At the end of the exercises, 2-3 minutes of light massage around the eyes and on sunny days, sunbathing was recommended by closing the eyes for 3-5 minutes and swinging to the left and right.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Convergence exercise group
Description: * Close eyes for 15 s,~* Focus on a point 1 to 1.5 ft away for 10 s,~* Close eyes for 5 s,~* Focus on a point 20 ft away for 10 s,~* Close eyes for 5 s,~* Focus on a point 1 to 1.5 ft away for 10 s,~* Blink for 5 s,~* Close eyes for 5 s.

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oculomotor Exercise Group (OMEG)
Description: * The saccadic eye movement exercise included moving the eyes horizontally between two stationary targets while keeping the head still.~* The smooth pursuit exercise included moving the target horizontally and tracking it with the eyes while keeping the head still.~* The adaptation X1 exercise included moving the head horizontally while keeping the stationary target in focus.~* The adaptation X2 exercise included moving the head and target in opposite directions horizontally while tracking the target with the eyes.
Study: NCT01828333

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT03713008

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Fluid bolus
Description: All patients included in the study will receive 5 ml/kg fluid bolus of a balanced crystalloid solution.
Study: NCT02290834

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive, functional and subjective assessments
Description: Cognitive and functional assessments

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive, functional and subjective assessments
Description: Cognitive and functional assessments

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive, functional and subjective assessments
Description: Cognitive and functional assessments

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: Magnetic Resonance Imaging (MRI) Scan
Study: NCT03707873

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: Education + Medication adherence monitoring + Feedback when low adherence
Study: NCT02290834

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: Magnetic Resonance Imaging (MRI) Scan

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: Magnetic Resonance Imaging (MRI) Scan
Study: NCT03812081

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Group A : Baska Mask Airway
Description: Size selection is based on the manufacturer's recommendation of weight-based estimate plus clinical judgment. The Baska Mask is available in four sizes: size three (30 to 50 kg), size four (50 to 70 kg), size five (70 to 100 kg),The membranous cuff of the Baska Mask appears bulkier than the equivalent inflatable cuff on cuffed laryngeal masks. The mask can easily be decreased in size during insertion by compressing the proximal, firmer part of the mask below the airway tube, between the thumb and two fingers

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Group B: Proseal Laryngeal Mask Airway
Description: Proseal LMA (size 3,4,5) was used for ventilation according of patient body weight.Size selection is based on the manufacturer's recommendation of weight-based estimate plus clinical judgment.
Study: NCT01958281

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOF
Description: Tablet(s) administered orally once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOF
Description: Tablet(s) administered orally once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RBV
Description: 200 mg tablet administered orally once daily

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RBV
Description: 200 mg tablet administered orally once daily
Study: NCT02290834

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: PET Scan
Description: Positron Emission Tomography (PET) Scan
Study: NCT01958281

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LDV/SOF
Description: 90/400 mg fixed-dose combination (FDC) tablet administered orally once daily
Study: NCT02290834

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: PET Scan
Description: Positron Emission Tomography (PET) Scan

Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: PET Scan
Description: Positron Emission Tomography (PET) Scan
Study: NCT04115917

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Schocket scleral depressor
Description: Scleral Depression on eye with Schocket scleral depressor

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cotton tipped applicator
Description: Scleral Depression on eye with cotton tipped applicator
Study: NCT03653949

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Educational intervention
Description: It will be an interactive lecture, 60 minutes long. The class will cover physiopathology, complications, treatment and prevention of exacerbations. Audiovisual resources and practical demonstrations of usual care will be used. Individual questions will be answered during the class.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational intervention
Description: It will be an interactive lecture, 60 minutes long. The class will cover physiopathology, complications, treatment and prevention of exacerbations. Audiovisual resources and practical demonstrations of usual care will be used. Individual questions will be answered during the class.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise
Description: The aerobic exercise program will be performed at home, on a cycle ergometer for lower limbs between 24 and 35 minutes: 5 minutes of warm-up, 14 to 25 minutes of high-intensity interval exercise and 5 minutes of cool down.
Study: NCT02350946

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Study: NCT01798407

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Activa Tremor Control Sys (DBS Implant)
Description: DBS system consists of the Activa RC 37612 System (Implantable Pulse Generator with Model 37085 Extensions (40 to 95cm), Activa Patient Programmer, and Medtronic Model 3389 DBS Lead). This system is commercially approved for the treatment of chronic, intractable Parkinson's Disease. It will be used with the Model SP-10344 Memory Mod Software which enables the physician to program the Implantable Pulse Generator to a higher frequency.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Randomized, staggered withdrawal phase
Description: For responders only: double blind discontinuation will be attempted on either the 12 or 13 month visit. Stimulation intensity will be decreased by 50% and then completely discontinued two weeks later. Subjects will be seen biweekly until 15 months post activation or escape criteria are met. These escape criteria include relapse at 2 visits, hospitalization, active suicidal ideation, or withdrawing consent. If any of these criteria are met, the blind will be broken and open treatment will be resumed.
Study: NCT03419598

Intervention type: PROCEDURE
Intervention: Opening wedge high tibial osteotomy
Description: Realignment of knee by creating an opening wedge osteotomy in the upper part of the tibia. Since this is a virtual trial, the virtual patients were duplicated and enrolled into both arms

Intervention type: DEVICE
Intervention: Personalised subject specific custom HTO plate
Description: Subject specific custom plate for stabilizing an open wedge HTO

Intervention type: DEVICE
Intervention: Generic HTO plate
Description: Generic plate for stabilizing an open wedge HTO
Study: NCT04843670

Intervention type: PROCEDURE
Intervention: duodenopancreatectomy
Description: resection of the head of the pancreas, the mower part of the biliary duct, and antrectomy
Study: NCT02770950

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zushima plaster with high dose
Description: Patients in high dose Zushima plaster group will use Zushima plaster topically on knee(s) for 24h per day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zushima plaster with low dose
Description: Patients in low dose Zushima plaster group will use Zushima plaster topically on knee(s) for 12h per day.

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Indometacin Cataplasms
Description: Patients in Indometacin Cataplasms group will use Indometacin Cataplasms on knee(s)for 24h per day.
Study: NCT04632823

Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Comprehensive Non-pharmacological Treatment Program
Description: dietary supplement, specific type of exercise, self-management education