Study: NCT02727712

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: bilateral thoracic paravertebral block
Description: group A under TPVB((TPVB T2/3+T5/6) by ropivacaine(0.3%,10ml\*4)program

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Transesophageal Echocardiography（TEE）
Description: 1. Apply Transesophageal Echocardiography（TEE）after anesthesia induction and draw 400ml autologous blood (Haemonetics®)used for the postoperative transfusion;~2. Goal-directed fluid management

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transesophageal Echocardiography（TEE）
Description: 1. Apply Transesophageal Echocardiography（TEE）after anesthesia induction and draw 400ml autologous blood (Haemonetics®)used for the postoperative transfusion;~2. Goal-directed fluid management

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transesophageal Echocardiography（TEE）
Description: 1. Apply Transesophageal Echocardiography（TEE）after anesthesia induction and draw 400ml autologous blood (Haemonetics®)used for the postoperative transfusion;~2. Goal-directed fluid management

Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Lung protection measure during the surgery（Dräger Primus）
Description: Protective ventilation strategy(Low tidal volume about 6\~7ml/kg, joint use of PEEP)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lung protection measure during the surgery（Dräger Primus）
Description: Protective ventilation strategy(Low tidal volume about 6\~7ml/kg, joint use of PEEP)

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lung protection measure during the surgery（Dräger Primus）
Description: Protective ventilation strategy(Low tidal volume about 6\~7ml/kg, joint use of PEEP)

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Anesthesia drugs during the surgery
Description: 1. Bilateral thoracic paravertebral block before induction of anesthesia;~2. Fast channel anesthesia • Induction use Sufentanil 0.5\~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate 0.2\~0.6mg/kg; ②. Maintain use Sufentanil Hydrochloride for Injection 0.01\~0.04ug/kg•min, Sevoflurane 0.5\~1.5MAC（minimum alveolar concentration） and Infusing Dexmedetomidine which load dose 0.5μg/kg in 10min then changed into 0.5-1.0μg/kg•h,Vecuronium 0.06\~0.12mg/kg•h; ③. Intravenous hydromorphone Hydrochloride Injection 0.15mg/kg before surgery over.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anesthesia drugs during the surgery
Description: 1. Bilateral thoracic paravertebral block before induction of anesthesia;~2. Fast channel anesthesia • Induction use Sufentanil 0.5\~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate 0.2\~0.6mg/kg; ②. Maintain use Sufentanil Hydrochloride for Injection 0.01\~0.04ug/kg•min, Sevoflurane 0.5\~1.5MAC（minimum alveolar concentration） and Infusing Dexmedetomidine which load dose 0.5μg/kg in 10min then changed into 0.5-1.0μg/kg•h,Vecuronium 0.06\~0.12mg/kg•h; ③. Intravenous hydromorphone Hydrochloride Injection 0.15mg/kg before surgery over.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anesthesia drugs during the surgery
Description: 1. Bilateral thoracic paravertebral block before induction of anesthesia;~2. Fast channel anesthesia • Induction use Sufentanil 0.5\~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate 0.2\~0.6mg/kg; ②. Maintain use Sufentanil Hydrochloride for Injection 0.01\~0.04ug/kg•min, Sevoflurane 0.5\~1.5MAC（minimum alveolar concentration） and Infusing Dexmedetomidine which load dose 0.5μg/kg in 10min then changed into 0.5-1.0μg/kg•h,Vecuronium 0.06\~0.12mg/kg•h; ③. Intravenous hydromorphone Hydrochloride Injection 0.15mg/kg before surgery over.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: thoracic paravertebral block
Description: group B under(TPVB T3/4)by ropivacaine(0.3%,20ml\*2)program