TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT02785094

Intervention type: BEHAVIORAL
Intervention: Observation
Description: Observation of Participants' behaviour

Intervention type: BEHAVIORAL
Intervention: Observation
Description: Observation of Participants' behaviour

Intervention type: BEHAVIORAL
Intervention: Observation
Description: Observation of Participants' behaviour

Intervention type: BEHAVIORAL
Intervention: Observation
Description: Observation of Participants' behaviour
Study: NCT02536209

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 low dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 low dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 low dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 low dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-8554 high dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone hydrochloride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone hydrochloride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone hydrochloride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone hydrochloride

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Study: NCT00811239

Intervention type: OTHER
Group type: OTHER
Intervention: Supportive Care
Description: Supportive Care only (endotracheal intubation, mechanical ventilation...)
Study: NCT04119700

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Muco-muscular endorectal advancement flap after fistulectomy
Description: After fistulectomy muco-muscular flap of the rectal wall will be mobilized. The muscular defect is sutured with separate interrupted sutures (Vicryl / Polysorb 2/0, 0/0, 3/0). The muco-muscular flap is fixed to the anoderm without tension by interrupted sutures (Vicryl / Polysorb 4/0). The wound of the perianal area is not sutured.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Primary sphincter reconstruction after fistulectomy
Description: Fistulectomy will be performed. The affected gland is visualized and removed. If there are secondary extensions, they are excised also. Sphincter defect with stitches (suture material Vicryl / Polysorb 2/0, 0/0, 3/0) with restoration of the anal canal profile (suturing of the anodermal-skin border). The skin is not suturing.
Study: NCT00950235

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight Management
Description: Two individual counseling session on nutrition and once weekly group sessions including use of food diaries for the remaining weeks of their pregnancy

Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care
Description: Standard nutrition counseling from Health Plan
Study: NCT00992745

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 123-I-MIP-1072
Description: Single 10 mCi intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 123-I-MIP-1072
Description: Single 10 mCi intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 111-In capromab pendetide
Description: Single 5 mCi intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 123-I-MIP-1072
Description: Single 5 mCi intravenous injection

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 123-I-MIP-1072
Description: Single 5 mCi intravenous injection
Study: NCT03708302

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Unilateral parasternal infrapectoral block
Description: Ultrasound guided unilateral serratus plane block will be performed at the level of 4th rib in anterior axillary line. After skin infiltration with 1% lidocaine, 80mm 22G block needle will be inserted at the caudal aspect of the ultrasound probe and advanced in-plane to target the fascial plane directly below the serratus muscle. Once the tip is verified in the correct position, 20 mls of 0.9% saline will be injected in the plane in 5 mls aliquot after aspiration.~Ultrasound guided unilateral parasternal infrapectoral plane block will be performed at the level of 4th rib, lateral to the sterum. After skin infiltration with 1% lidocaine, 80mm 22G block needle will be inserted at the caudal aspect of the ultrasound probe and advanced in-plane to target the fascial plane directly below the pectoralis major muscle. Once the tip is verified in the correct position, 20 mls of 0.9% saline will be injected in the plane slowly in 5 ml aliquots after aspiration.
Study: NCT01554332

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Motor Cortex Stimulation using SJM EonC Stimulator
Description: Patients will be randomized to receive either active stimulation the first 3 months followed by a one-month washout, followed by Sham Stimulation the next 3 months, vs. the reverse order of treatment, followed by single blind stimulation, and an open label phase.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Motor Cortex Stimulation using SJM EonC Stimulator
Description: Patients will be randomized to receive either active stimulation the first 3 months followed by a one-month washout, followed by Sham Stimulation the next 3 months, vs. the reverse order of treatment, followed by single blind stimulation, and an open label phase.
Study: NCT04830345

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ATGC-100 100U
Description: Clostridium botulinum toxin type A

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Botox 100U
Description: Clostridium botulinum toxin type A
Study: NCT03948958

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evaluation of the catheter function
Description: Catheter function will be measured by the CINAS (Catheter injection and aspiration classification)
Study: NCT03708302

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Unilateral parasternal infrapectoral block
Description: Ultrasound guided unilateral serratus plane block will be performed at the level of 4th rib in anterior axillary line. After skin infiltration with 1% lidocaine, 80mm 22G block needle will be inserted at the caudal aspect of the ultrasound probe and advanced in-plane to target the fascial plane directly below the serratus muscle. Once the tip is verified in the correct position, 20 mls of 0.9% saline will be injected in the plane in 5 mls aliquot after aspiration.~Ultrasound guided unilateral parasternal infrapectoral plane block will be performed at the level of 4th rib, lateral to the sterum. After skin infiltration with 1% lidocaine, 80mm 22G block needle will be inserted at the caudal aspect of the ultrasound probe and advanced in-plane to target the fascial plane directly below the pectoralis major muscle. Once the tip is verified in the correct position, 20 mls of 0.9% saline will be injected in the plane slowly in 5 ml aliquots after aspiration.
Study: NCT03791684

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cross linking
Description: Cross linking strategy either standard or accelerated
Study: NCT03948958

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Catheter tip location, thrombus, sleeve and device damage visualization
Description: Catheter tip location, thrombus, sleeve and device damage will be visualized by linogram

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Catheter-related colonization
Description: TIVAD colonization will be investigated by microbiological culture of the tip and chamber content

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: patient-reported outcome measures (PROM) related to the presence of the TIVAD
Description: PROM will evaluate patient's experiences regarding the TIVAD insertion, dwell time, and removal using the Leuven Patient Reported Experiences at Port removal (Leuven PREP) questionnaire.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Macroscopic evaluation of the port chamber and catheter
Description: Macroscopic evaluation of the port chamber and catheter will be performed after port removal.
Study: NCT04410445

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bempegaldesleukin
Description: Specified dose on specified days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified dose on specified days
Study: NCT00809653

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: No Face Mask
Description: Subjects will not wear a face mask to reduce their personal air pollution exposure

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Face Mask
Description: Subjects will be asked to wear a simple face mask to reduce personal exposure to particulate air pollution. Subjects will be asked to wear the mask for 24 hours prior to the study day and the 24 hours of the study day. They will be instructed to wear the mask at all times when outdoors and as much as possible when indoors.
Study: NCT04410445

Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Nivolumab
Description: Specified dose on specified days
Study: NCT03655366

Intervention type: OTHER
Intervention: Questionnaire for Dog owners
Description: Questionnaire directed to epileptic patients, parents of epileptic children and legal representatives of epileptic patients with intellectual disabilities. It includes questions about demographics, epilepsy diagnosis, seizures, the behavior of their dogs around the time they have a seizure and a validates scale to measure dog personality traits.

Intervention type: OTHER
Intervention: Questionnaire for Dog trainers
Description: Questionnaire for seizure response and seizure alert dog trainers including information on number of active working dogs, dog demographic information and selection criteria, the type of patient inclusion criteria they use, training methods used.
Study: NCT00088166

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hCRF
Description: hCRF ; open-label dexamethasone that the patient is currently taking

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo hCRF
Description: placebo hCRF 2mg/day and open-label dexamethasone that they are taking
Study: NCT01581099

Intervention type: PROCEDURE
Intervention: Digestive Adaptations III surgery
Study: NCT00651703

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CYT004-MelQbG10 + Montanide

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CYT004-MelQbG10 + Montanide + Imiquimod
Study: NCT03594760

Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-DCFPyL IV injection
Description: Patient will receive one injection of 18F-DCFPyL and undergo PET-CT imaging
Study: NCT04113018

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfilzomib, lenalidomide, dexamethasone (KRd) + Daratumumab
Description: Experimental
Study: NCT03513094

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transversus Abdominis Contraction
Description: Participants were educated on how to contract their transversus abdominis (TA) muscle after having a surface EMG biofeedback device placed on their abdomen to provide audible biofeedback. Participants were asked to ambulate while maintaining TA contraction while ambulating at 50% of maximal volitional isometric contraction.
Study: NCT01346293

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Diphtheria and Tetanus Toxoids and Acellular Pertussis + Measles, Mumps, Rubella + Varicella Virus
Description: 0.5 mL, Intramuscular (DTap-IPV); Subcutaneous (M-M-R®II and VARIVAX®)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Diphtheria and Tetanus Toxoids and Acellular Pertussis + Poliovirus + MMR + Varicella Virus
Description: 0.5 mL, Intramuscular (IM) DAPTACEL®; Subcutaneous (SC) MMR®II and VARIVAX®; IM or SC IPOL®

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Diphtheria and Tetanus Toxoids and Acellular Pertussis + Measles, Mumps, Rubella + Varicella Virus
Description: 0.5 mL, Intramuscular (DTap-IPV); Subcutaneous (M-M-R®II and VARIVAX®)

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Diphtheria and Tetanus Toxoids and Acellular Pertussis + Poliovirus + MMR + Varicella Virus
Description: 0.5 mL, Intramuscular (IM) DAPTACEL®; Subcutaneous (SC) MMR®II and VARIVAX®; IM or SC IPOL®
Study: NCT01391897

Intervention type: BEHAVIORAL
Intervention: psychotherapy
Description: multimodal complex psychotherapy
Study: NCT03062761

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Infant Formula with prebiotics
Description: Intervention group: Partially hydrolysed whey protein based infant formula containing prebiotics.

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Infant Formula
Description: Control group: Intact cow's milk protein based infant formula containing prebiotics
Study: NCT02521805

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Animal protein

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Animal protein

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Animal protein

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vegetable protein

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary fiber (cereal food matrice)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary fiber (meat food matrice)

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary fiber (vegetable food matrice)
Study: NCT04388553

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: single shot lumbar Erector Spinae Plane block
Description: unilateral (operative side), performed at L1 level, under ultrasound guidance
Study: NCT02100488

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Closed-loop insulin infusion system
Description: Each subject will undergo two Open-loop and two Closed-loop meal tests, each one at 1-2 week intervals, thus completing the 4 experiments in about 6 weeks. The day of the experiment, a standard mixed meal test containing 60 g of carbohydrates (CHO), will be administered. On two occasions, patients will receive in a randomized order the standard insulin bolus based on the individual insulin to CHO ratio (First arm, Open-loop study). On the other two occasions they will receive a Sliding Mode Reference Conditioning (SMRC) Closed-loop insulin administration, based on subcutaneous continuous glucose monitoring (Second arm, Closed-loop study). Commercial insulin infusion systems and continuous glucose monitoring devices will be used.
Study: NCT03499327

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Wheat germ oil (UV treated)
Description: Wheat germ oil is naturally rich in vitamin D precursors (ergosterol and 7-dehydrocholesterol), which are converted into vitamin D2 and vitamin D3 by a defined UV light irradiation for the present study (wheat germ oil (UV treated).~The wheat germ oil (UV treated) is dispensed in dark glass bottles without label. The distinction between the groups is based on the expiration date (08.05.2018 vs. 09.05.2018). The distinction between the groups is not possible for the participants.~The daily dosage of wheat germ oil is 10 ml and the study products will be consumed over an entire period of 6 weeks (no follow-up).~Recommendation for intake: pure before a main meal.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Wheat germ oil (untreated)
Description: commercial available wheat germ oil The wheat germ oil (untreated) is dispensed in dark glass bottles without label. The distinction between the groups is based on the expiration date (08.05.2018 vs. 09.05.2018). The distinction between the groups is not possible for the participants.~The daily dosage of wheat germ oil is 10 ml and the study products will be consumed over an entire period of 6 weeks (no follow-up).~Recommendation for intake: pure before a main meal.
Study: NCT04166539

Intervention type: BEHAVIORAL
Intervention: Questionnaires
Description: You will be asked to complete a questionnaire about your family history of neurological diseases and current and past physical thinking activities.

Intervention type: BEHAVIORAL
Intervention: Questionnaires
Description: You will be asked to complete a questionnaire about your family history of neurological diseases and current and past physical thinking activities.
Study: NCT02100488

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Open-loop insulin infusion system
Description: Standard subcutaneous insulin infusion based on the individual insulin to carbohydrate ratio. Commercial insulin infusion systems and continuous glucose monitoring devices will be used.
Study: NCT04166539

Intervention type: BEHAVIORAL
Intervention: Interviews
Description: Behavioral and Memory interviews will take place with the patient.

Intervention type: BEHAVIORAL
Intervention: Interviews
Description: Behavioral and Memory interviews will take place with the patient.

Intervention type: OTHER
Intervention: Blood draw
Description: Have a sample of blood drawn (4.2-5 tablespoons) for clinical and research tests.

Intervention type: OTHER
Intervention: Blood draw
Description: Have a sample of blood drawn (4.2-5 tablespoons) for clinical and research tests.

Intervention type: RADIATION
Intervention: Magnetic Resonance Imaging
Description: Each MR examination takes about 45 minutes and does not require the use of needles, medication or contrast enhancement. You will lie on your back and enter the MR scanner for the study, during which time you will hear knocking noises. People with pacemakers, aneurysm clips, cochlear implants, or metal/foreign objects in their eyes are not permitted to undergo MR studies. We will review your implants and determine your eligibility.

Intervention type: RADIATION
Intervention: Magnetic Resonance Imaging
Description: Each MR examination takes about 45 minutes and does not require the use of needles, medication or contrast enhancement. You will lie on your back and enter the MR scanner for the study, during which time you will hear knocking noises. People with pacemakers, aneurysm clips, cochlear implants, or metal/foreign objects in their eyes are not permitted to undergo MR studies. We will review your implants and determine your eligibility.

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiogram
Description: Each echocardiogram takes about 30 minutes. This test uses sound waves to look at your heart. The person doing the test will press on your chest with a machine to obtain the pictures. The pressure may be uncomfortable. The echocardiogram will involve an image enhancement agent infusion to obtain better images.

Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiogram
Description: Each echocardiogram takes about 30 minutes. This test uses sound waves to look at your heart. The person doing the test will press on your chest with a machine to obtain the pictures. The pressure may be uncomfortable. The echocardiogram will involve an image enhancement agent infusion to obtain better images.
Study: NCT01257035

Intervention type: OTHER
Intervention: 18F-FAZA-PET/CT
Description: Contrast fluid injected prior to scan
Study: NCT00206934

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Escitalopram
Description: Either 10 mg of escitalopram or placebo will be administered to a group of healthy volunteers

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: escitaolpram
Description: Either 15 mg of escitalopram or placebo will be administered to healthy volunteers
Study: NCT05019768

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: accelerated custom-fast CXL
Description: The accelerated custom fast CXL (aCFXL) has been developed on a published mathematical model that takes into consideration objective variables such as the equation governing the UVA-induced riboflavin consumption rate and the corneal thickness at its thinnest point. By knowing both values, the mathematical model allows to objectively calculate both the exact UVA irradiation value (intensity), expressed in mW/cm2, and the irradiation time

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard CXL
Description: The standard CXL procedure has been carried on following the Dresden protocol
Study: NCT02772770

Intervention type: OTHER
Intervention: Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions
Description: The non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions.

Intervention type: PROCEDURE
Intervention: Surgical technique: Transphyseal reconstruction
Description: Study physicians will have the option to treat ACL injuries operatively or non-operatively, according to their standard of care. However, once the decision is made to manage the injury operatively or non-operatively, the physician must follow the appropriate standardized treatment protocol developed for the study. The operative treatment protocol will include standardized surgical techniques for transphyseal reconstruction with soft tissue graft and metaphyseal fixation.

Intervention type: PROCEDURE
Intervention: Surgical technique: Partial transphyseal reconstruction
Description: Study physicians will have the option to treat ACL injuries operatively or non-operatively, according to their standard of care. However, once the decision is made to manage the injury operatively or non-operatively, the physician must follow the appropriate standardized treatment protocol developed for the study. The operative treatment protocol will include partial transphyseal reconstruction (tibial transphyseal and femoral epiphyseal) with soft tissue graft.

Intervention type: PROCEDURE
Intervention: Surgical technique: Physeal sparing reconstruction by the Anderson method
Description: Study physicians will have the option to treat ACL injuries operatively or non-operatively, according to their standard of care. However, once the decision is made to manage the injury operatively or non-operatively, the physician must follow the appropriate standardized treatment protocol developed for the study. The operative treatment protocol will include standardized surgical techniques for physeal sparing epiphyseal reconstruction with soft tissue graft (Anderson technique).

Intervention type: PROCEDURE
Intervention: Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method
Description: Study physicians will have the option to treat ACL injuries operatively or non-operatively, according to their standard of care. However, once the decision is made to manage the injury operatively or non-operatively, the physician must follow the appropriate standardized treatment protocol developed for the study. The operative treatment protocol will include physeal-sparing with Iliotibial band combined extra-articular and intra-articular reconstructions (Micheli/Kocher Technique).