Study: NCT02407314

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous Peripheral Intervention
Description: Percutaneous peripheral intervention is a common procedure performed by cardiologists to revascularize peripheral arterial lesions in patients (stent placement). This procedure is considered standard of care and is not experimental.

Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Percutaneous Peripheral Intervention
Description: Percutaneous peripheral intervention is a common procedure performed by cardiologists to revascularize peripheral arterial lesions in patients (stent placement). This procedure is considered standard of care and is not experimental.

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optical Coherence Tomography
Description: This is an established medical imaging technique that uses light to capture micrometer-resolution, three-dimensional images from within optical scattering media. The device used is a cardiac catheter with OCT sensors on the tip of it. It will be used to assess the artery vessels after Percutaneous Peripheral Intervention.

Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Optical Coherence Tomography
Description: This is an established medical imaging technique that uses light to capture micrometer-resolution, three-dimensional images from within optical scattering media. The device used is a cardiac catheter with OCT sensors on the tip of it. It will be used to assess the artery vessels after Percutaneous Peripheral Intervention.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ankle Brachial Index
Description: This a clinical assessment and consists of the calculation of the ratio of the blood pressure in the lower legs to the blood pressure in the arms. The ABI is calculated by dividing the systolic blood pressure at the ankle by the systolic blood pressures in the arm.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Ankle Brachial Index
Description: This a clinical assessment and consists of the calculation of the ratio of the blood pressure in the lower legs to the blood pressure in the arms. The ABI is calculated by dividing the systolic blood pressure at the ankle by the systolic blood pressures in the arm.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Six minute walk distance
Description: Assessment of the walking distance in 6 minutes.

Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Six minute walk distance
Description: Assessment of the walking distance in 6 minutes.

Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Aspirin
Description: Aspirin, also known as acetylsalicylic acid \[ASA\], is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin + Ticagrelor
Description: This is a combination of drugs (Aspirin + Ticagrelor). Ticagrelor is a platelet aggregation inhibitor due to its properties as an antagonist of the P2Y12 receptor. Ticagrelor is a nucleoside analogue: the cyclopentane ring is similar to the sugar ribose, and the nitrogen rich aromatic ring system resembles the nucleobase purine, giving the molecule an overall similarity to adenosine.