Study: NCT02632526

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension crystalline form (1 to 100 mg/mL) (Part A)
Description: Oral suspension single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension crystalline form (1 to 100 mg/mL) (Part A)
Description: Oral suspension single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension crystalline form (1 to 100 mg/mL) (Part A)
Description: Oral suspension single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension crystalline form (1 to 100 mg/mL) (Part A)
Description: Oral suspension single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension crystalline form (1 to 100 mg/mL) (Part A)
Description: Oral suspension single dose

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part A)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 placebo oral suspension
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Description: Single and multiple doses

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718 oral suspension amorphous (1 to 100 mg/mL) (Part B)
Description: Single and multiple doses