TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04341922

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-delivered cognitive behavior therapy (ICBT) for dysfunctional worry related to the Covid-19 pandemic
Description: The intervention focuses on 1) teaching participants how to discriminate between functional and dysfunctional worry (what are solvable problems vs. what is worry, i.e. unsolvable thoughts?) 2) providing participants with skills to solve functional worry topics (e.g. set time and make a workable plan to be prepared for possible negative outcomes \[e.g. becoming unemployed\]), 3) helping participants to reduce unhelpful behaviors that may reinforce worry (e.g., limit excessive news consumption, refrain from assurance seeking behaviors), 4) providing participants with skills to approach dysfunctional worry (e.g., not engage in worrisome thoughts, just leave them), and 5) increase the behavioral repertoire (take walks, engage in activities that promote health without putting oneself at risk to become infected).
Study: NCT03884972

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trabectedin
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trabectedin
Description: Given IV

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study: NCT01743937

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Coronary occlusion with balloon inflation
Study: NCT02676739

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adderall XR

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adderall XR

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Adderall XR
Study: NCT03770338

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Teriparatide
Description: 20ug dosage daily injection, 1-month preoperative
Study: NCT02747459

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sensory Supported Swimming
Description: A swimming and water safety program for children with autism spectrum disorders. Individualized instruction utilizing evidence-based teaching methods and sensory modifications.
Study: NCT03376204

Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study: NCT06719648

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acellular dermal matrix + L-Prf
Description: Incisions: Incisions were made in the gums using a specialized scalpel. Flap Elevation: The gum tissue was lifted away from the underlying bone using a dental elevator.~Partial Thickness Dissection: The tissue was cut to release tension and allow for easier repositioning.~Interdental Papilla Elevation: The gum tissue between the teeth was partially lifted.~Flap Extension: The flap was extended to cover more teeth for better coverage. Tissue Separation: The flap was carefully separated from underlying tissues to allow for proper positioning.~Root Preparation: The exposed root surfaces were smoothed and cleaned.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Connective Tissue graft + L-Prf
Description: Incisions: Incisions were made in the gums using a specialized scalpel. Flap Elevation: The gum tissue was lifted away from the underlying bone using a dental elevator.~Partial Thickness Dissection: The tissue was cut to release tension and allow for easier repositioning.~Interdental Papilla Elevation: The gum tissue between the teeth was partially lifted.~Flap Extension: The flap was extended to cover more teeth for better coverage. Tissue Separation: The flap was carefully separated from underlying tissues to allow for proper positioning.~Root Preparation: The exposed root surfaces were smoothed and cleaned.
Study: NCT00967187

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bevirimat dimeglumine
Description: Patients will be treated with MPC-4326 200mg monotherapy for 14 days. Once the Day 15 viral load results become available, patients, who achieve at least a 0.5 log10 reduction in viral load by Day 15 will have the option to continue on both MPC-4326 and an optimized background regimen (OBR) through Week 72.

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bevirimat dimeglumine
Description: Patients will be treated with MPC-4326, 300 mg monotherapy for 14 days. Once the Day 15 viral load results become available patients who achieve at least a 0.5 log10 reduction in viral load by Day 15 will have the option to continue on both MPC-4326 and an optimized background regimen (OBR) through Week 72.
Study: NCT01543269

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ZYT1
Description: Oral dose of ZYT1 in fasting condition with 240±10 ml of water at sitting position in ambient temperature.

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablets
Description: Oral dose of Placebo in fasting condition with 240±10 ml of water at sitting position in ambient temperature.
Study: NCT04596358

Intervention type: OTHER
Intervention: Observational
Description: Evaluation of adherence to the Mediterranean diet through the administration of the Med Diet Score questionnaire.

Intervention type: OTHER
Intervention: Observational
Description: Evaluation of adherence to the Mediterranean diet through the administration of the Med Diet Score questionnaire.
Study: NCT01825499

Intervention type: OTHER
Intervention: Registry
Study: NCT03559452

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Eccentric exercise
Description: 300 eccentric contractions of the knee extensors
Study: NCT03345459

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ICare Prevent (internet-based treatment for depression in college students)
Description: ICare Prevent (internet-based treatment for depression in college students): 7 weekly sessions and 1 booster session. Each session requires about 30-45 minutes to complete. All sessions are accessed online, and it is a guided treatment (i.e., each patient provided an eCoach).
Study: NCT04449549

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nilotinib and Paclitaxel
Description: The BCR-Abl kinase inhibitor nilotinib demonstrated greater than additive activity in combination with the anti-tubulin agent paclitaxel in preclinical xenograft models, justifying the clinical evaluation of this combination for its antitumor activity
Study: NCT03414515

Intervention type: DEVICE
Intervention: Endovascular intervention
Description: Endovascular treatment with stent or balloon according to current practice
Study: NCT05134142

Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Undergo medical record review

Intervention type: OTHER
Intervention: Physical Performance Testing
Description: Undergo physical performance testing

Intervention type: OTHER
Intervention: Quality-of-Life Assessment
Description: Complete assessments
Study: NCT02439086

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PET-CT Scan
Description: patients will have 2 PET CT scans: one before radiotherapy, and one 9 weeks after.
Study: NCT05134142

Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Complete questionnaire
Study: NCT04512352

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online curriculum
Description: The psychologist and our advisory team had successfully developed a total of 100 hours of parenting curriculum.~The adopted curriculum had focused on using play to facilitate parents in promoting their children's development in cognitive, motor, emotional and social aspects. Play-based activities are instrumental in improving children's development. Given that parents in poverty had difficulties spending time and money travelling back-and-forth to the training site and their homes, the research team decided to use e-learning as the medium of learning for our parenting programme. Web-based learning has the advantage of cutting time and travelling costs, which are luxuries to many parents in poverty.
Study: NCT01592968

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive Assessment
Description: Ancillary studies
Study: NCT01458171

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Immune globulin subcutaneous (Human)
Description: IgPro20 is a 20% (weight per volume \[w/v\]) liquid formulation of human immunoglobulin for subcutaneous (SC) use. Subjects will receive weekly infusions of IgPro20 for a total of 24 weeks at a dose based on the subject's IgPro20 dose in the pivotal study ZLB06_002CR (NCT01199705).
Study: NCT00022776

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical decompression
Description: Simple decompression not requiring fusion.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Physical therapy
Description: 2 physical therapy sessions per week for 6 weeks Followed by home program.
Study: NCT04736784

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food-based - beetroot juice
Description: Beetroot juice containing approximately 340 mg nitrate daily
Study: NCT03457168

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Treatment of elevated asleep SBP mean
Description: To reduce asleep SBP mean determined by 48h ambulatory blood pressure monitoring up to the randomly assigned target by hypertension treatment intensification when required

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Treatment of elevated asleep SBP mean
Description: To reduce asleep SBP mean determined by 48h ambulatory blood pressure monitoring up to the randomly assigned target by hypertension treatment intensification when required
Study: NCT03809169

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rapid on-site evaluation (ROSE)
Description: Pathologist on site for direct evaluation of specimen adequacy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rapid on-site evaluation (ROSE)
Description: Pathologist on site for direct evaluation of specimen adequacy

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Slim bronchoscope without a guide sheath
Description: peripheral endobronchial ultrasound performed with a slim bronchoscope (3.0 mm outer diameter with a 1.7mm channel) combined with a radial ultrasound probe but without the use of a guide sheath.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Slim bronchoscope without a guide sheath
Description: peripheral endobronchial ultrasound performed with a slim bronchoscope (3.0 mm outer diameter with a 1.7mm channel) combined with a radial ultrasound probe but without the use of a guide sheath.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard pEBUS with guide sheath
Description: Using a flexible bronchoscope with minimal outer diameter of 4.2mm.
Study: NCT04736784

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food-based - leafy green vegetable juice
Description: Leafy green vegetable juice containing approximately 340 mg nitrate daily
Study: NCT02466945

Intervention type: DEVICE
Group type: OTHER
Intervention: V063B-DP3003
Description: The medical device V063B-DP3003 has been developed to relieve and decrease dentinal hypersensitivity in patients by creating a film around the sensitive tooth in order to prevent pain. Application modalities: apply a pea size amount of product (around 0.5g) onto each of the sensitive teeth, 3 times a day, by gentle massage with clean finger after each brushing of teeth. Do not rinse
Study: NCT02659059

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified Dose on Specified Days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified Dose on Specified Days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Specified Dose on Specified Days

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Specified Dose on Specified Days

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Platinum Doublet Chemotherapy
Study: NCT03976102

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DRL_RI (Proposed rituximab biosimilar)
Description: Proposed rituximab biosimilar, 100mg and 500mg, concentrate for solution for infusion

Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MabThera®
Description: Reference product rituximab, 100mg and 500mg, concentrate for solution for infusion
Study: NCT00761059

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glucose 20%
Description: The oral application of 0,3 ml/kg Glucose 20% 3 minutes before nasopharyngeal suctioning

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Aqua
Description: The oral application of 0,3 ml/kg Aqua 3 minutes before nasopharyngeal suctioning
Study: NCT01739322

Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Prick test Platanus acerifolia allergen extract
Description: This is an open, unblinded and non randomized biological as proposed by the Nordic Guidelines.~Four concentrations of Platanus acerifolia allergen extract, together with a positive and negative control, using 10 mg/ml histamine dihydrochloride solution and a glycerinated phenol saline solution, respectively, will be tested in every patient in duplicate on the volar surface of the forearm. This test will be referred to as the Titrated Skin Prick test.
Study: NCT02041455

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin and Placebo

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amitriptyline and Placebo

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Melatonin and Amitriptylin
Study: NCT01541657

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ankle Joint Mobilization
Description: The posterior ankle mobilization treatment is a manual therapy technique that consists of gently gliding your ankle in the backward direction through a pain free range of motion. This is a common therapy technique used by athletic trainers for the treatment of ankle sprains. The objective of this therapy technique is to glide the ankle into the area which restricts range of motion and gently stretch the restricted area. To begin this treatment, a certified athletic trainer with experience in applying this therapy technique will provide mild traction to the ankle joint to lightly distract the bones of the ankle joint. The athletic trainer will then apply two sets of joint mobilizations which will each last 2 minutes. Each repetition will consist of gently gliding the ankle joint in the backward direction until an area of restriction is reached. The athletic trainer will push into the restriction and then glide the ankle back to the starting position.

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Foot Massage
Description: The foot massage treatment is a manual therapy technique that consists of gently rubbing the bottom of your feet with both hands like kneading dough. To begin the treatment, you will be asked to lie comfortably on a treatment table you're your feet hanging slightly off the edge. The athletic trainer with experience in applying this therapy will place his hands on the bottom of your foot and begin to massage your feet from your toes down to your heel. The athletic trainer will perform 2 sets of 2 minutes of massage with 1 minute rest in between sets.
Study: NCT03662737

Intervention type: DIAGNOSTIC_TEST
Intervention: Visuomotor adaptation task
Description: We will measure performance of the subjects of each group on the visuomotor adaptation task, especially in the rotation condition, in which a perturbation will be induced between the anticipated location of the hand and the provided visual feedback, and in the washout condition, in which the rotation will be removed. We expect that subjects with cannabis use disorder will not show the expected implicit motor adaptation to the perturbation and consequently no deterioration of performance on the task, due to cannabis-induced cerebellar damage. In other words, we want to show that this visuomotor task is a cheap and quick biomarker of cerebellar dysfunction in chronic cannabis users.
Study: NCT01541657

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calf Stretching
Description: The calf stretching treatment is a technique that is commonly used in sports and rehabilitation. You will be asked to place your foot on a slant board located next to a wall with your heel positioned below your toes on the slant board. You will be asked to lean towards the wall until you feel tension in your calf muscles that feels like a good stretch. You will perform 2 sets of 3 stretches that are held for 30 seconds each. Between each stretch, you will rest for 10 seconds. Between each set, you will rest for 1 minute.
Study: NCT03662737

Intervention type: DIAGNOSTIC_TEST
Intervention: Visuomotor adaptation task
Description: We will measure performance of the subjects of each group on the visuomotor adaptation task, especially in the rotation condition, in which a perturbation will be induced between the anticipated location of the hand and the provided visual feedback, and in the washout condition, in which the rotation will be removed. We expect that subjects with cannabis use disorder will not show the expected implicit motor adaptation to the perturbation and consequently no deterioration of performance on the task, due to cannabis-induced cerebellar damage. In other words, we want to show that this visuomotor task is a cheap and quick biomarker of cerebellar dysfunction in chronic cannabis users.

Intervention type: DIAGNOSTIC_TEST
Intervention: Visuomotor adaptation task
Description: We will measure performance of the subjects of each group on the visuomotor adaptation task, especially in the rotation condition, in which a perturbation will be induced between the anticipated location of the hand and the provided visual feedback, and in the washout condition, in which the rotation will be removed. We expect that subjects with cannabis use disorder will not show the expected implicit motor adaptation to the perturbation and consequently no deterioration of performance on the task, due to cannabis-induced cerebellar damage. In other words, we want to show that this visuomotor task is a cheap and quick biomarker of cerebellar dysfunction in chronic cannabis users.
Study: NCT00755716

Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (sugar pill)
Description: patients receive

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topiramate
Description: 25 mg per day for one week, 50 mg per day for one week, 100 mg per day for one week, 200 mg per day for 5 weeks, then one week taper
Study: NCT01224496

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chinese herbal concoction twice a day for 6 months
Description: Definition of each TCM syndrome is based on TCM theory. Formulation composition is based on each defined TCM syndrome with addition or removal of herbs as indicated by the patient's manifestation
Study: NCT03293342

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: D CBT
Description: Intervention:~a 3-5 session treatment of dental fear.~* Psychoeducation about anxiety~* Exploration of the individual anxiety~* Exposure to the frightening stimuli (no hiding, but actively showing in detail all components of dental treatment, preferably utilizing a mirror while doing treatment).

Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Intervention:~Traditional treatment of dental fear common sense/ benzodiazepine
Study: NCT00575848

Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Glycine
Description: Subjects will consume glycine twice daily, once with breakfast and once with dinner. The medication is in liquid form. They will be instructed to refrigerate the liquid until the time that they take it. Subjects start by taking 10g per day for the first 2 days. Starting on the 3rd day, subjects take 0.2g/kg (15g for a 75kg adult) per day, and increase dosage by 0.2g/kg every two days, until they reach 0.8g/kg per day, which they take for the remainder of the 6-week period.

Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will consume placebo twice daily, once with breakfast and once with dinner. The placebo is in liquid form. They will be instructed to refrigerate the liquid until the time that they take it. Subjects start by taking 10g per day for the first 2 days. Starting on the 3rd day, subjects take 0.2g/kg (15g for a 75kg adult) per day, and increase dosage by 0.2g/kg every two days, until they reach 0.8g/kg per day, which they take for the remainder of the 6-week period.
Study: NCT00755716

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topiramate
Description: 25 mg per day for one week, 50 mg per day for one week, 100 mg per day for one week, 200 mg per day for 5 weeks, then one week taper

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine patch
Description: On the quit date (after 2 weeks of Topiramate medication use), subjects also use 21 mg patch for 7 weeks and on week 8 subjects received 14 mg/day for 3 days then 7 mg for 4 days.
Study: NCT00977041

Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neurofeedback
Description: Electrodes will be placed over the temporal lobes bilaterally and a ground electrode placed on the left earlobe. EEG activity will be amplified using a Procomp 2 or Nexus amplifier, and EEGer software will be used to provide subjects with feedback. Contingencies will be set such that alpha brain activity will be reinforced, and high beta and theta brain activity will be inhibited. Standard NF training procedures will be used, which involve simply asking subjects to relax while looking at the feedback screen and Do whatever is necessary to make and keep the bar wide. This protocol will be repeated for up to 40 60-minute sessions (that will include 30 minutes of NF training), scheduled at least weekly.
Study: NCT01592968

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies

Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: Undergo SRS
Study: NCT03191344

Intervention type: BEHAVIORAL
Intervention: with IPSS
Description: all patient in one group use IPSS to record the parathyroid status. the other group operation as ordinary. record the parathyroid status in verbal description
Study: NCT03209908

Intervention type: DRUG
Intervention: Tenofovir Disoproxil Fumarate
Description: Tenofovir Disoproxil Fumarate was used for the experimental group of pregnancy women in the 32 weeks during pregnancy
Study: NCT01390246

Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupropion SR
Description: Bupropion SR 150 mg tablet

Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Smoking Cessation Counseling
Description: 35-min counseling by trained research nurse
Study: NCT04641156

Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Therapy program added to laser therapy
Description: a supervised physical therapy exercise program for the neck muscles in the form of manual mobilizations for sternocleidomastoid muscle and upper fibers of trapezius in addition to myofascial trigger point release