Study: NCT03432806

Intervention type: OTHER
Intervention: blood draws
Description: Patients will have 10 mL of peripheral venous blood drawn immediately prior to surgery, in the post anesthesia care unit (PACU), and at the first postoperative clinic visit for a total of 30 mL.

Intervention type: OTHER
Intervention: blood draws
Description: Patients will have 10 mL of peripheral venous blood drawn immediately prior to surgery, in the post anesthesia care unit (PACU), and at the first postoperative clinic visit for a total of 30 mL.

Intervention type: OTHER
Intervention: blood draws
Description: Patients will have 10 mL of peripheral venous blood drawn immediately prior to surgery, in the post anesthesia care unit (PACU), and at the first postoperative clinic visit for a total of 30 mL.

Intervention type: PROCEDURE
Intervention: colectomy or hepatectomy
Description: Three small pieces of otherwise normal-appearing liver of 0.5-1 cm3 collected intraoperatively from patients in all four groups (including Group D). Because liver biopsy is less frequently performed during operations for benign colon lesions or Stage I-III colon cancers, this single aspect of the protocol can be made optional at the discretion of the surgical attending or the patient, however bloods and tissue from pathology will still be collected.

Intervention type: PROCEDURE
Intervention: colectomy or hepatectomy
Description: Three small pieces of otherwise normal-appearing liver of 0.5-1 cm3 collected intraoperatively from patients in all four groups (including Group D). Because liver biopsy is less frequently performed during operations for benign colon lesions or Stage I-III colon cancers, this single aspect of the protocol can be made optional at the discretion of the surgical attending or the patient, however bloods and tissue from pathology will still be collected.

Intervention type: PROCEDURE
Intervention: colectomy or hepatectomy
Description: Three small pieces of otherwise normal-appearing liver of 0.5-1 cm3 collected intraoperatively from patients in all four groups (including Group D). Because liver biopsy is less frequently performed during operations for benign colon lesions or Stage I-III colon cancers, this single aspect of the protocol can be made optional at the discretion of the surgical attending or the patient, however bloods and tissue from pathology will still be collected.

Intervention type: PROCEDURE
Intervention: colectomy or hepatectomy
Description: Three small pieces of otherwise normal-appearing liver of 0.5-1 cm3 collected intraoperatively from patients in all four groups (including Group D). Because liver biopsy is less frequently performed during operations for benign colon lesions or Stage I-III colon cancers, this single aspect of the protocol can be made optional at the discretion of the surgical attending or the patient, however bloods and tissue from pathology will still be collected.

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibroscan test
Description: This may be done either at a preoperative clinic setting or immediately prior to surgery.

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibroscan test
Description: This may be done either at a preoperative clinic setting or immediately prior to surgery.

Intervention type: DIAGNOSTIC_TEST
Intervention: Fibroscan test
Description: This may be done either at a preoperative clinic setting or immediately prior to surgery.