Study: NCT02584751

Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole
Description: Omeprazole is a commonly prescribed anti-reflux medication. If a SCI patient has GERD, they will be prescribed with 40mg omeprazole twice daily for two months

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 24 Hour pH Monitor
Description: Monitors the acidity and levels of pH in the esophagus for 24hours and helps diagnose people with GERD

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 24 Hour pH Monitor
Description: Monitors the acidity and levels of pH in the esophagus for 24hours and helps diagnose people with GERD

Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 24 Hour pH Monitor
Description: Monitors the acidity and levels of pH in the esophagus for 24hours and helps diagnose people with GERD

Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 24 Hour pH Monitor
Description: Monitors the acidity and levels of pH in the esophagus for 24hours and helps diagnose people with GERD

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary Function Examination
Description: Assess pulmonary function such as lung volumes, spirometry, and max inspiration/expiration pressures.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary Function Examination
Description: Assess pulmonary function such as lung volumes, spirometry, and max inspiration/expiration pressures.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary Function Examination
Description: Assess pulmonary function such as lung volumes, spirometry, and max inspiration/expiration pressures.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary Function Examination
Description: Assess pulmonary function such as lung volumes, spirometry, and max inspiration/expiration pressures.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exhaled Nitric Oxide
Description: Used to measure inflammation markers for airway resistance.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exhaled Nitric Oxide
Description: Used to measure inflammation markers for airway resistance.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exhaled Nitric Oxide
Description: Used to measure inflammation markers for airway resistance.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exhaled Nitric Oxide
Description: Used to measure inflammation markers for airway resistance.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exhaled Breath Concentrate (EBC)
Description: EBC will be used to measure airway inflammation via specific markers, such as 8-isoprostane. This marker, if elevated, has been identified as an indicator for asthma inflammation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exhaled Breath Concentrate (EBC)
Description: EBC will be used to measure airway inflammation via specific markers, such as 8-isoprostane. This marker, if elevated, has been identified as an indicator for asthma inflammation.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exhaled Breath Concentrate (EBC)
Description: EBC will be used to measure airway inflammation via specific markers, such as 8-isoprostane. This marker, if elevated, has been identified as an indicator for asthma inflammation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exhaled Breath Concentrate (EBC)
Description: EBC will be used to measure airway inflammation via specific markers, such as 8-isoprostane. This marker, if elevated, has been identified as an indicator for asthma inflammation.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bernstein's Acid Clearance Test
Description: Bernstein test is a clinical test for the diagnosis of chest pain in association with gastric acid exposure

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bernstein's Acid Clearance Test
Description: Bernstein test is a clinical test for the diagnosis of chest pain in association with gastric acid exposure

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bernstein's Acid Clearance Test
Description: Bernstein test is a clinical test for the diagnosis of chest pain in association with gastric acid exposure

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bernstein's Acid Clearance Test
Description: Bernstein test is a clinical test for the diagnosis of chest pain in association with gastric acid exposure

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Esophageal Motility
Description: Esophageal Motility will be used to measure a subject's ability to swallow a bolus (i.e. saline solution) and record pressure changes throughout the esophagus during the swallow. This will also be used to identify anatomical landmarks, such as lower esophageal sphincter, which are necessary for proper placement of 24hr pH catheter.

Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Esophageal Motility
Description: Esophageal Motility will be used to measure a subject's ability to swallow a bolus (i.e. saline solution) and record pressure changes throughout the esophagus during the swallow. This will also be used to identify anatomical landmarks, such as lower esophageal sphincter, which are necessary for proper placement of 24hr pH catheter.

Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Esophageal Motility
Description: Esophageal Motility will be used to measure a subject's ability to swallow a bolus (i.e. saline solution) and record pressure changes throughout the esophagus during the swallow. This will also be used to identify anatomical landmarks, such as lower esophageal sphincter, which are necessary for proper placement of 24hr pH catheter.